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Level Four needed a new logo design and created a contest on 99designs.
A winner was selected from 99 designs submitted by 38 freelance designers.
We are a website design and development company looking to rebrand.
Please read the brief carefully.
Level Four
Weare a website design and development company looking to rebrand.
There are currently four (4) sub-businesses under the Level Four 'brand'.
The 'brand name' of the business is 'Level Four', with four sub-businessesbeing:
- Level Four Media
- Level Four Direct
- Level Four Hosting
- Level Four Development
The new logo will be used for web (primary) and print (secondary).
We would like the logo to have both an image and stylised text; the image is tobe the logo for all the sub-businesses, and the text will represent theindividual sub-business.
We intend to add additional sub-businesses under the Level Four brand thereforethe text logo must be adaptable.
The design must as clean, simple and easy to reproduce (please do not use finelines).
The current logo can be seen at: http://www.levelfour.com.au
- Text inlogo must be all lower case.
- Colourversion and black/white version.
- Clean & simple.
- Scalable.
- Favicon.
- Adobe Illustrator files.
- Use Univers font (not 100% necessary).
- Stylised text that can be trademarked.
- The words 'levelfour' to appear as one word and in black – the sub-business asanother word in a different colour.
- Anything cliché.
- Do not use the numeral '4' in any way.
- Please do notuse fine lines.
Find out how a design contest works or learn more about our logo design services.


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Hi all
I just felt like dropping a line to say, things are really good for me at the moment.
I'm out of the disaster with Greek ex, though it took a few more rounds of chaos for me to finally break free. I've even run into Italian ex in my area, and feel balanced about it now; like I haven't gone back to him, either.
I've got a new job starting soon and it's really well paid and good for me, so I'm looking forward to that. I'm sort of seeing a nice German chap who so far is treating me well, but nothing serious yet.
Even my charity stuff is improving, and my brother now lives locally to me.
I seem to be making lots of new friends in my new area that I moved to about a month ago.
All in all, things are better than ever.

subset: commoncrawl


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posted by Thom Holwerda on Tue 11th Feb 2014 23:11 UTC
The Amiga Operating System implementation of FUSE has been realized via a project called Filesysbox by Leif Salomonsson. A special thanks goes out to Leif for allowing his hard work to be utilized.
Amiga programmer extraordinaire Fredrik Wikström was then commissioned to port Filesysbox over to AmigaOS. Fredrik took the original code and updated it to AmigaOS 4.1 standards. This work included utilizing advanced DOS features such as object notification and the new file system API which seeks to completely avoid the esoteric DOS packet interface. Colin Wenzel is the main man behind the advanced DOS features.
Since I'm sure at least some of you will do a double-take upon reading this summary: they're referring to another kind of DOS.


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Fusion Energy Sciences (FES)
Click here (83KB) (83.0KB) for a printable version of the map below showing locations across the United States where major fusion research is currently conducted. Click on the each institution or industry to be taken to the website.
This page includes links to various U.S. and International institutions -- including Academic Institutions, Government Laboratories, and Private Industry -- with fusion or plasma physics programs. Please send suggestions for additions to this list or for corrections / updates to firstname.lastname@example.com.
DOE National Laboratories
Other Government Laboratories
Private Industry
International Institutions
Please send suggestions for additions to this list or for corrections or updates to firstname.lastname@example.com .
The appearance of hyperlinks does not constitute endorsement by the Department of Energy of these web sites or the information, products or services contained therein.
The Office of Science (SC) is the single largest supporter of basic research in the physical sciences in the United States.


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The ! I received was very high in quality, It is better than anything out there I've seen in this price range. It is a great buy. The quality is great for the price!
I was searching for a gift to send someone in a secret santa exchange and as soon as I saw this folding bed I knew it would be perfect! So cute! Simple and elegant. Bought one for myself and for a friend and she loved it.
I can't say enough nice things about this folding bed. I appreciate the other reviewers noting that this runs large.This folding bed fits beautifully. The color is very rich. Love it! I will be purchasing another one of these in a different color.
I bought this folding bed as a New Year gift for my daughter. It is just as described online. folding bed looks nice although i feel it's over priced. Should come with nicer packaging for the price.
$407.98 $147.99 $228.99 $149.99 $446.99 $195.99


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Project Reader API v.1
Budget €750-1500 EUR
Build a joint API between three project file types.
Awarded to:
I can develop API and small demo application for this API. Relevant Skills and Experience I have about 10 years experience of C/C++ programming. Proposed Milestones €1300 EUR - Develop API, Fix errors
20 freelancers are bidding on average €1273 for this job
Database web applications are our main specialization. Please see our previous projects on this website, almost all of them were such systems. Relevant Skills and Experience Please pay attention: we completed many ex More
Hey there, I am able to develop a joint API between different project file types. Relevant Skills and Experience I have very complex API's behind my back. Proposed Milestones €1250 EUR - Milestone Are you able to p More
HI. I am new here but i am a programmer with over 8 years experience. I am very good at C++ and API. I am c++ king. Relevant Skills and Experience Please check check the following links to see about our work. All imag More
Hi, Let me keep this really short as I am sure you would be swamped with the proposals! First, please note that we have developed applications that backend in PHP (Laravel,Yii, CodeIgniter, CakePHP or Symfony) a More
Dear Client, I am an experienced mobile app & web developer who has great and various skills. I have built over 100+ apps so far and you can check them on my profile. I can manage native android & iOS, unity 3d ga More
[login to view URL] is not another mindless automated bid. I am a Visual Basic .NET programmer with 10 years experience. CV and see screenshots+videos of exe softwares i made> [login to view URL] Stay tuned, I'm is sti More
Hello, As per your requirement we are specialist in API integration and creating API Relevant Skills and Experience we are professional team of developer and designer. we can prove our skill in any kind of development More


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It was great for this group," Chambers said. "It was great for them to take a couple hits and get back up and throw some hits.
STATE COLLEGE, Pa. — Two grueling three-hour practices the last couple days following two Big Ten losses had Penn State refocused on rebounding and defense.
The drills paid off handsomely Thursday night in a 65-45 win over Purdue.
Billy Oliver scored a career-high 21 points and Penn State held the Boilermakers to a season-low 31-percent shooting to snap a six-game losing streak against Purdue and secure first-year coach Patrick Chambers' first Big Ten win with the Nittany Lions (9-7, 1-2).
"It was all about staples, defending and rebounding. Doing the little things," guard Tim Frazier, who added 15 points, said about the recent practices. "There was no doubt in my mind that we would go out and compete. I didn't know what the score would be at the end of the game, but I knew we would go out and compete."
Frazier hit a leaning banker in traffic in the lane to extend the lead to 54-38 with about 8 minutes left. The tough bucket capped an 18-6 run to put the game out of reach.
Robbie Hummel's 14 points and five rebounds paced Purdue (12-4, 2-1), which lost to Penn State for the first time since a 67-64 defeat three years ago in Happy Valley.
This one wasn't nearly as close. Playing with four fouls, Oliver hit back-to-back 3s with just 5 minutes left for a 19-point lead. The Nittany Lions outhustled their opponents and outrebounded them 38-26.
"Our guys won a couple games and they were fat and sassy," Purdue coach Matt Painter said.
Matt Glover led Penn State on the glass with 11 rebounds, to go with five assists and two steals.
"If we could get somebody to play as hard as Matt Glover," Painter lamented. "He made a lot of hustle plays for them and that's something we've really prided our program in, doing whatever it takes — guarding rebounding and being unselfish."
D.J. Byrd had 12 points for Purdue, which narrowed a 15-point deficit in the first half to 36-32 off Hummel's layup with 15:15 left.
But Penn State regrouped and went on a 7-0 run finished by Frazier's layup on the break following a steal by Glover.
An uncharacteristically sloppy first half left Purdue trailing 32-18 halftime, the Boilermakers' lowest-scoring half of the season. Penn State held Purdue without a field goal the final 6:46 of a half in which coach Matt Painter's club committed seven turnovers, or about three fewer than its average for an entire game.
The enthusiastic Chambers has used the word "attitude" as an energetic slogan for his squad all season. He relies on his players to battle under the boards and hustle for loose balls.
"It was great for this group," Chambers said. "It was great for them to take a couple hits and get back up and throw some hits."
Oliver, a 6-foot-8 forward who likes to roam the perimeter, scored 12 in the first half on 4-of-6 shooting from 3-point range.
"When Billy plays like that it really opens up a lot of things for" Frazier, Chambers said. "Now you don't know who to stop."
Penn State led by as much as 15 in the half on Sasa Borovnjak's layup with 3 minutes to go before Purdue made its second-half push.
Jermaine Marshall added 10 points and five rebounds for the Nittany Lions, who played without starting guard Cammeron Woodyard (left hamstring).


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Car Deals
Hatchback Deals: February 2014
If you're interested in excellent gas mileage and unrivaled practicality, it's hard to beat a hatchback. We certainly have a few favorites, and we've included them in our latest list of hatchback deals and special offers. It's a good place to start if you're searching for a hatchback.
Chevrolet Sonic
The Chevrolet Sonic is a subcompact car offered as a sedan or a 5-door hatchback. We prefer the hatchback. And through the end of the month, shoppers who feel the same way can get one with an excellent deal. For qualified drivers looking to finance, Chevrolet is offering 0 percent interest for up to 60 months on the 2013 Sonic, or 3.9 percent for up to 60 months on the 2014 model. For those paying in full, Chevrolet is offering up to $500 cash back on the 2014 model -- a deal that jumps to $1,500 back for the 2013 Sonic.
Find a Chevrolet Sonic for sale
Ford Fiesta
The Ford Fiesta is a subcompact car offered as a sedan or a 5-door hatchback. Due to its added practicality, we especially like the hatchback. And through the end of the month, the 2014 model is offered with several excellent deals. For qualified drivers interested in financing, Ford is offering 0 percent interest for up to 60 months. For drivers paying in full, Ford is touting up to $1,500 cash back -- a good deal considering the model's base price is in the mid-$15,000 range. And while Ford is only offering a special lease deal this month on the Fiesta sedan, we think hatchback buyers could get pretty close to the sedan's $179 monthly payment with some good negotiating.
Honda Fit
The Honda Fit is a 5-door hatchback that offers excellent gas mileage and clever interior packaging for ample room. With a new model on the way, the 2013 Fit is offered with several excellent deals in February. The best is a low-interest offer, which gives qualified shoppers 0.9 percent interest for up to 60 months, or 1.9 percent for 72 months. But lease shoppers don't miss out on the deals, as Honda has two lease incentives available: a 36-month term with nothing down and payments from $200 per month, or the same term with $1,999 down and monthly payments from $149.
The Mazda3 is a compact car offered in sedan or 5-door hatchback body styles. We prefer the hatchback, both for its excellent styling and its added practicality. We also like the fact that it's currently offered with two excellent deals. The best one is a low interest rate of just 0.9 percent, which is available to qualified shoppers for up to 36 months on the 2014 Mazda3 hatchback. If you'd rather lease, the 2014 Mazda3i Sport is available with payments from $209 per month for 36 months after $2,299 down at lease signing.
Toyota Prius c
The subcompact Prius c is a 5-door hatchback that holds the title of America's most efficient vehicle that doesn't need to be plugged in. In February, it's offered with two excellent incentives. For qualified drivers looking to finance, Toyota is touting 0 percent interest for up to 36 months on all 2013 Prius c models. For shoppers looking to lease, Toyota has a similarly enticing deal available: a 36-month term with payments from $179 per month. The only drawback is that taking advantage of the lease deal requires $2,578 down at lease signing.
Find a Toyota Prius C for sale
What it means to you: Some of today's best hatchback deals and incentives are currently available on many of our favorite new models.


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Deliver a Delivery Person in a clean white Carton
Similar images:
- Bright Light Shines from Open White Carton Background
- New Home boxed for sale in a clean white House Carton
- Shipping department icons & elements boxes & people
- Mystery Box - question mark in a clean white carton
- Woman Hand Picks Symbol Business Man from Row of Businessmen
- Team of Suits with Briefcases Symbol Business People Ready to Wo
- Hand selects business man silhouette from group of people
- Magnifying Glass Chooses Silhouette Person in People Row
- Magnifying Glass to Choose Person in Row of People on Background
- Magnifying Glass Chooses Inspects Man in Row of People
Vector of Deliver a Delivery Person in a clean white Carton
|For web use only – 72 dpi
|Social Media Mobile Applications Blogs / Websites
|For print or web use – 300 dpi
|Web Templates Invitations Presentation
|Brochures Publishing Billboards
|For print or web use - vector
Scalable to any size without losing image quality; can be used for any printing or online applications.Vector Closeup Pixels Closeup
Choose the right image size
When choosing an image size or EPS file to download, keep these simple rules in mind:
- All images can be reduced in size without losing image quality.
- Increasing the size of an image (up-sizing) will cause the image to become blurry and lose quality. The more you enlarge, the blurrier or more distorted the image can become.
- It's best to buy a size that's close to or one size larger than the final size you need.


text:
Our websites use cookies to make browsing as smooth as possible. For full details and options, just visit our cookies page.
Having trouble accessing some of our online products or demos? It could be because your internet connection is blocking some parts of the CGP website. Or you might need to upgrade to a newer browser. Still stuck? Just contact us and we will be happy to help.
The GCSE Range
Select a Subject or Book Type to browse our awesome GCSE range (Ages 14-16)


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Rating: 2.1/5 (Total votes: 30)
What's New in This Release:
· Fixed Night Mode's issue in RSS
· Fixed Night Mode crash on particular Android devices
· Improve compatibility with KitKat
What's New in 126.96.36.1990:
· Added search suggestions in the address bar
· Support for the Immersive Mode on KitKat
What's New in 22.214.171.1240:
· Added more websites for you to choose from and add to your Quick Access. Just click the + button to view the websites we handpicked for you.
What's New in 126.96.36.1990:
· Fixed text display issues in some languages.
· Improved the effect of Quick Access icon's carousel.
· Fixed the issue of cursor absence in address bar.
What's New in 18.104.22.1680:
· Scan any QR code by clicking on a button in the address bar
· Back up your Quick Access and NewsBites to secure your favorite websites during updates
What's New in 18.104.22.1680:
· Search in page and save pages easily, with new options in the long-tap menu.
· Launch Google Play app right from the browser.
· Faster speed and better performance.
What's New in 18.104.22.1680:
· Fixed display issues after long tap or moving icon in Quick Access.
· Fixed bugs about UA's setting.
· Fixed the upload issues for web forms.
· Fixed the media files' disappearance after downloaded.
What's New in 126.96.36.1990:
· Showing information in a new tab in first running.
What's New in 220.127.116.110:
· NewsBites Now: With this new feature you will never miss the most important local and global news. The NewsBites Now notification will appear every time new content is available and your content has been updated.
What's New in 18.104.22.1680:
· History timeline
What's New in 220.127.116.110:
· New full screen mode hides notification bar.
· Adding a helpful beauty circle in the full screen mode.
What's New in 18.104.22.1680:
· Sliding browser window on tablet.
· Adding NewBites into 7 inch tablet version.
» show all
FreewareAndroid - Free Downloads Android Market Apps, Applications, Games, APK, WiFi, Sync, GPS for Google Android OS


text:
Not only is Michelle Elaine one of New York's most sought-after wedding planners, but she's an avid marathoner and certified personal trainer. She loves helping brides whip into shape before the Big Day, and Michelle is sharing some of her favorite slim down moves you can do just about anywhere. Pair this nine-step circuit with a clean eating plan and you'll see big results in no time.
Lie on your right side keeping a steady form with your shoulders, chest, hips and legs in line with one another (*If you find yourself leaning forward or backward, and/or having difficulty keeping your balance just lean down on your elbow instead of fully extending your right arm.) You're going to hold this position for 30-60 seconds, then switch to your left side and hold for another 30-60 seconds.
Get into a full plank position, as if you are about to start a push-up. From here, bring down your right arm and then your left so you get yourself into a plank position, and then lift your arms back up, leading with your right arm into that full plank position. You will keep bringing your arms down and up for 30-60 seconds, then switch to start with your left arm & perform for another 30-60 seconds.
Similar to the Tree Plank except this time both legs are fully extended and you will now dip your side down to just touch the ground and then bring back up. Perform these dips for 30-60 seconds and then switch to your opposite side for another 30-60 seconds.
Get into a full plank position and just place your left arm behind your back. Hold your body steady, don't dip your hips down or push your butt up. Hold this position for 30-60 secondsand then switch arms.
This one is a little tough! Get into full plank position and then raise your right arm and left leg, hold for 30-60 seconds and then switch for left arm and right leg. (*This may be difficult to keep balance, if you need to, just kneel on the balancing leg.)
Get down on all fours and just lift your right foot to a 90-degree angle/hip height so that your foot is flat to the ceiling. Press up for a few inches as you bring that foot up and then lower back down and repeat for 30-60 seconds. Switch to your left foot & repeat for another 30-60 seconds.
Balance yourself into a full plank position with either a yoga ball or medicine ball and then lift your left leg and hold for 30-60 seconds while keeping balance. Then switch to your right leg & hold for another 30-60 seconds. (*The yoga ball, and/or a medicine ball will add difficulty so you can certainly opt for just having hands flat on the ground instead.)
Exactly what you're thinking, just a basic push-up! But push-ups can transform your upper body & muscle tone! Start in a full plank position and then bring your body down & push-up. (*If you feel your hips sinking or your butt pushing up, place both knees down for assistance & keep the body steady.) Perform 10-15 push-ups.
Stand straight, head, shoulders, hips and feet aligned. Cross left arm over right & hold at a 90-degree angle, then lunge forward with your left leg. Continue to lunge forward alternating legs for 30-60 seconds. Then hold the lunge for 30-60 seconds and switch, this time starting with the right leg.


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Luxury Hotels and Resorts in Miami
The Best in Miami Luxury
Whether you're looking to party in luxury, enjoy some of the best weather around, or simply indulge in some top world cuisine, a luxury hotel break in Miami ticks all those boxes and much more.
The beautiful people can be found lazing on Miami Beach and it's easy to see why they've made this their mecca. Some of the most exciting nightlife in the United States can be found here, including the 5 star clubbing experiences of Cameo, Mansion and Mynt Lounge. Expect celebs and superstar DJs, as well as the city's most discerning party animals.
It's doing Miami a disservice to suggest it's just one bit party, though. The boutique shopping outlets of Ocean Drive and Collins Avenue cater to all tastes and interests. If nature is what you seek, the Everglades is home to one of the most spectacular ranges of animals around.
Booking a luxury Miami break with Kiwi Collection will earn you VIP upgrades and services as well as our hand-picked selection of the best hotels. Why book anywhere else?
locations in Miami
Featured Hotels
Wow PicksHotels that made us say WOW!


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These Blu Dot Flume Side Table is very popular end table! We offer the special offer! you may buy it at special price from this page. Please check our special prices and compare prices. If you would like to order the end table today but you are worried about lastest price will be reduced, Please Don't care because you would like to own Blu Dot Flume Side Table Now and you have enough money to order it. you should ask yourself, Why do you waiting to order?, If you don't have a great reason, I think you can buy now but you would like to see any more information before to order.
1. Make sure to always select "Ship to: USA", because international shipping is much more expensive.
2. Prealert your packages. For packages under $100 save $3 of AeroProtect.
3. Use our online calculator to get an estimate of the import costs for the product you're interested in, and make sure it's more convenient to buy it online.
4. If you have a Basic account and you receive at least 2 packages per month, switch to a Gold, Platinum or Diamond account and save up to 25% in freight.
5. Ask your provider to send your order in as few shipments as possible.
6. Sign-up with your favorite online stores and receive their notifications when they have sales and special offers.
7. Take advantage of US holidays; it's when they offer the best sales.
Great end table! Love the material and fit! Will buy in other colors as well! I love this Blu Dot Flume Side Table. I bought the black first and then ordered the white. I love the fit,too. I may buy another color later if it continues to be available.
Love the design and color. Good quality for the price. I was looking at this end table for months and finally happy that I made the purchase! I get so many compliments on the color! Glad I made the decision to buy it... Great for everyday use! Super happy.
This is a beautiful end table and very high-quality. I have now bought this for my special one and it's one of their favorites that they wear all the time! You won't be disappointed!! It is very pretty, and appears to be a high quality piece. Beautiful!
$419.99 $251.99 $252.99 $309.99 $389.99 $349.99 $415.99


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The vice president for enrollment planning and management is responsible for the recruitment and enrollment of undergraduate and graduate students, as well as relevant marketing initiatives. In addition, the vice president is responsible for initiating and managing national and international collaborations, including enrollment at the University's satellite campuses in Massachusetts and Madrid, Spain.
Reporting to the vice president are:
- assistant vice president for enrollment and director of student financial services
- assistant vice president for enrollment and registrar for the colleges
- assistant vice president for enrollment and director of undergraduate admission
- director of graduate admission
- director of international enrollment services
- director of international student outreach


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SOURCE: Burrill & Company
January 02, 2013 08:45 ET
Best Performance Since 1996 as Orphan Drugs Step Into the Spotlight, Burrill & Company Reports
Best Performance Since 1996 as Orphan Drugs Step Into the Spotlight, Burrill & Company Reports
SAN FRANCISCO, CA--(Marketwire - Jan 2, 2013) - The U.S. Food and Drug Administration approved eight new drugs in December pushing the year's total to 39, its highest level since 1996 when the agency cleared a backlog of applications.
Though December's newly approved drugs cover a broad range of conditions, the agency had granted orphan drug status to six of the eight medicines. Orphan drug status confers financial and other benefits to a drug's sponsor to encourage the development of drugs to treat patient populations of 200,000 or less in the United States. In fact, nearly half of the 39 drugs approved in 2012 had orphan drug designations.
"We've seen drugmakers embrace orphan drugs for a variety of reasons including the opportunity to win faster approvals and run smaller, less costly clinical trials, and better chances of success," says G. Steven Burrill, CEO of Burrill & Company, a global financial services firm focused on the life sciences. "The passage in 2012 of new incentives for developing rare disease drugs will only further fuel this trend, particularly as more precision therapies are developed to target subpopulations of patients with a given disease."
Trading activity of biotech stocks echoed the positive year for new drug approvals as life sciences stocks soared in 2012. The Burrill Select Index ended the year up 40.5 percent. That compares to a 7.3 percent increase in the Dow Jones Industrial Average, a 13.4 percent gain for the S&P 500, and a 15.9 percent rise in the Nasdaq Composite Index. An improving economy, clinical advances, new product approvals, and M&A activity drove the gains. Sarepta Therapeutics posted the biggest gain in 2012 with its shares rising 477 percent. The company in 2012 reported that its mid-stage experimental muscular dystrophy drug demonstrably improved the ability to walk for boys taking the drug.
Congress also helped biotech stocks stay on track in 2012 with smooth passage of legislation to renew the Prescription Drug User Fee Act, which provides for the U.S. Food and Drug Administration authority to collect fees from industry for reviewing products in exchange for assurances that it will act on applications in a timely manner. The legislation, approved as part of the Food and Drug Administration Safety and Innovation Act, also provided for accelerated approval paths and other incentives for drugmakers developing new therapies to treat rare disease and could help the development of personalized medicines that target small subpopulations of patients.
With a U.S. Supreme Court decision that left most of President Barack Obama's landmark healthcare reform legislation intact, and Obama's reelection, the fight over healthcare reform is shifting from efforts to repeal the legislation to fights over its implementation.
The past year also saw the passage of the Jumpstart Our Business Startups or JOBS Act, which seeks to make it easier for emerging growth companies to access capital through the public markets. The act provides exemption from compliance with costly regulations for smaller companies. It also allows companies to test investor interest before having to make sensitive information public in securities regulatory filings.
U.S. life sciences companies raised a record amount of capital in 2012 with a total of $71.1 billion in public and private financings, up from $57.4 billion in 2011, a 23.9 percent increase. When the potential value of partnering transactions are included in the numbers, the total for 2012 grows to $91.7 billion, a 13.9 percent increase over the $80.4 billion raised through financings and partnering transactions in 2011.
Global life sciences venture financings totaled more than $12.4 billion in 2012, an increase of nearly 23 percent over 2011. Venture investors, however, are moving away from early-stage financings. Companies are relying more on alternative sources of financing, including accelerators, angel capital, corporate venture sources, and private equity investment. In fact, of the top 10 private financings in 2012, all but one had significant backing from private equity firms or strategic investors.
When venture investors do fund early-stage companies, increasingly they are providing large rounds to carry a company to proof-of-concept when investments can be exited or new financing at higher valuations can be raised. While privately held therapeutics developers grabbed the largest portion of funding with a total of $5.1 billion in 2012, digital health and life sciences information technology deals showed the biggest jump in activity, with a 58.5 percent increase to $748 million.
A total of 16 life sciences companies completed initial public offerings in the United States through December 31, the same as last year. Shares of U.S. life sciences IPOs returned an average of 15.3 percent from their initial offering price through the end of 2012. Of the 16 issues, 12 came in below their target range. Overall, these companies sold their shares at an average of 23.2 percent below the median of their target price. The 12 therapeutics companies that debuted in public markets in 2012 outperformed life sciences IPOs as a whole. Those issues rose 25.9 percent for the year.
Companies in 2012 announced a total of $109.2 billion in M&A transactions, down 31.2 percent from the activity a year ago. Big Pharma and Big Biotech continue to be the most active acquirers. While generic drugs and consumer health were big areas of activity, the top deals involving innovative biopharmaceuticals in 2012 included Bristol-Myers Squibb's $7 billion acquisition of Amylin Pharmaceuticals, GlaxoSmithKline's $3 billion purchase of Human Genome Sciences, and Dainippon Sumitomo Pharma's $2.6 acquisition of Boston Biomedical, which is developing drugs to target cancer stem cells.
Global partnering deals were valued at $37.6 billion in 2012, a 1.3 percent decline over the same period a year ago. Discovery deals led the way with a total of 70 transactions, followed by preclinical (45), phase 2 (43), already marketed (40), phase 1 (28), and phase 3 (25) transactions. Most deals are back-end loaded with significant milestones tied to the achievement of sales targets for drugs that are approved and marketed. Besides AstraZeneca's $3.4 billion buy-in to collaborate with Bristol-Myers' newly acquired Amylin diabetes franchise, Allergan's agreement with Swiss biotech Molecular Partners to develop and commercialize a class of biologics aimed at treating serious eye diseases was the largest deal of the year with $62.5 million in upfront payments and a potential total value of $1.4 billion.
The U.S. Food and Drug Administration's approval of 39 new drugs and biologics represented a 14.7 percent increase from the 34 approved in 2011. These approvals included Vertex Pharmaceuticals' Kalydeco, a targeted therapy for cystic fibrosis patients who have a specific gene mutation that drives their disease. Pfizer won approval for Xeljanz, the first oral disease-modifying drug for rheumatoid arthritis in more than a decade. The year also saw the European Medicines Agency issue the first approval in the western world for a gene therapy, UniQure's Glybera, a treatment for a rare, inherited disease where patients are unable to handle fat particles in their blood plasma.
There were also some notable innovations in 2012 in the way approved drugs were made. Pfizer, along with its partner Protalix Biotherapeutics, won approval for the Gaucher disease drug Elelyso, the first drug to be manufactured using genetically engineered plant cells. Novartis, notably won approval for Flucelvax, the first seasonal influenza vaccine licensed in the United States produced using cultured animal cells instead of fertilized chicken eggs.
Despite ongoing financial concerns in Europe and the United States, as well as tensions in the Middle East, the life sciences are poised for positive results in 2013. The arrival of the $1,000 genome is rapidly advancing the clinical applications of whole genome sequencing and the promise of personalized medicine to improve care and cut costs is starting to be realized.
Emerging digital health technologies are pushing this trend further. As the demand to transition healthcare to a value-based system continues, the importance of digital health technologies will reverberate through virtually every aspect of healthcare. In 2013, these technologies will grow in importance as they empower patients to take greater control over their own health and wellness, provide real-time monitoring to improve efforts to prevent disease and improve outcomes, and help payers and providers harness vast amounts of new data, transforming it into actionable information that improves care and reduces costs.
Burrill & Company's Predictions for 2013:
For the life sciences in 2013, Burrill expects the following:
Capital Markets
While the world economy continues to improve, turmoil in the Middle East, economic instability in Europe, and political dysfunction in the United States threaten to disrupt a tenuous recovery.
Expect to see the financing environment improve once the fight in the United States over budget cuts and taxes is resolved. In 2013, expect the industry to raise $100 billion in capital, with financings heavily weighted to the large companies and to the use of debt.
Private Financings
Traditional venture investors will become less relevant to start-ups as they continue to migrate not only toward later-stage deals, but public company investments as well. Angel, corporate venture, disease advocacy groups, and philanthropic organizations will fill the growing gap. In order to get funding, companies will need to convince investors they have a clear path to market, ability to get paid for their products, a way to demonstrate value to customers or payers, and an exit opportunity for their investors. Larger financing rounds that get a company to proof-of-concept will become the norm, not the step financings of the past.
With growing wealth in emerging markets, investors in these parts of the world will become more prominent and new cultures of entrepreneurship will give rise to a growing number of life sciences startups outside the United States. Expect private financings to grow 20 percent in 2013.
Bolstered with increased public market activity, the JOBS Act, and more realistic outlooks about the pricing of their offerings, the number of life sciences IPOs will grow to 25 in 2013.
Mergers & Acquisitions
Expect this number to increase by at least 20 percent with a pick-up in acquisitions of mid-cap life sciences companies and at least one Big Pharma or major biotech merger in 2013. Deals targeting drug companies that reach into Latin America, the Middle East, and Southeast Asia, will also drive activity.
Pharmaceutical companies in 2012 focused much of their partnering efforts on discovery collaborations as they worked to externalize their research operations. This trend will continue as drugmakers seek to reduce their costs and broaden their sources of innovative ideas.
Competition to license experimental drugs will increase; however, pharmaceutical companies will insist on sharing risk with their partners and provide small upfront payments with rewards coming only if milestones are met.
Global Dealmaking
As developing countries look to grow their economies and provide for their growing populations and rising middle classes, companies will have more opportunities to take advantage of local needs to obtain capital and market access on more attractive terms. Latin America will be hot, as life sciences companies look beyond just Brazil to other countries in the region. China will continue to be a desired place for dealmaking. India will be seen as a big opportunity for bioinformatics as the country's information technology strengths and lower cost services are embraced by the life sciences. Even Russia will become a bigger player with more acquisitions than sales of companies.
Clinical trials
In an effort to reduce development costs, drugmakers will increase their use of adaptive trial designs that allow them to modify studies in ways that make use of data as it is collected, but don't compromise the validity of the study.
Payers will increasingly reimburse whole genome sequencing selectively on an individual patient basis as the falling cost of sequencing drives doctors' interest in making use of the tool for diagnostic purposes.
Comparative effectiveness will become a reality for drugmakers in 2013 as they prepare to meet the growing demand of payers to demonstrate value and justify pricing of their new products. Investors will shift emphasis from a focus on whether a drug will be approved, to whether payers will see value in a product and if companies will be able to capture value.
We expect a total of 35 new drugs to be approved in 2013 as drugmakers take advantage of mechanisms to accelerate approval.
FDA will enter into public-private partnerships to reach earlier into the product development pipeline of both drug and device makers to work with industry to improve the tools they use to evaluate biomedical innovation.
Cooperation between regulators around the world will increase to improve post approval monitoring of regulated products.
National Institutes of Health
Regardless of what happens with sequestration, expect NIH funding to decrease in real dollars. It will force researchers that relied on grants to find alternative sources of funding and lead to new initiatives to fund academic research.
As there will be increasing pressure on drugmakers and payers to define the subpopulation of patients that respond to therapies, there will be a shift in value towards diagnostics from drugs.
Focus in 2013 will shift from the $1,000 genome to the $100 genome. It's real. It's happening. It's the diagnostic of tomorrow.
A new cost-consciousness will permeate patients and providers as new value-based approaches to healthcare take hold. Patients will look past the traditional delivery of healthcare and rely on new digital tools to comparison shop for services. Providers will place a greater emphasis on cost control within their facilities as they move toward billing for outcomes rather than services.
Digital Health
Digital health technologies will grow ubiquitous as doctors and patients grow comfortable with using their everyday digital devices to manage health. As comfort levels grow, increasing sophistication will be layered on to monitor patients and share information with doctors. The convergence of wireless technologies, social medial, and low-cost monitoring devices and sensors will provide consumers with new ways to take control of their own health and wellness.
In 2013, there will be expanded use of biopesticides to combat insects and microoganisms that damage crops. Plant breeders will harness emerging technologies, such as RNAi, to produce a new generation of products that allow for greater crop yields without the stigma of producing foods that are considered genetically modified.
Despite the defeat of California's Proposition 37, anti-GMO sentiment will continue to be a problem for the industry, particularly in Europe and increasingly in Asia.
The biorenewables industry will begin to see the first commercial projects come on line but until the industry starts to generate real revenues, raising capital will remain difficult and partnering will remain a critical lifeline for its growth.
Industrial Biotechnology
Advances in synthetic biology will begin to transform manufacturing of everything from fragrances to fabrics as engineered organisms produce materials traditionally derived from plants and petroleum.
About Burrill & Company
Founded in 1994, Burrill & Company is a diversified global financial services firm focused on the life sciences industry. With $1.5 billion in assets under management, the firm's businesses include venture capital/private equity, merchant banking, and media. By leveraging the scientific and business networks of its team, Burrill & Company has established unrivaled access and visibility in the life sciences industry. This unique combination of resources and capabilities enables the company to provide life sciences companies with capital, transactional support, management expertise, insight, market intelligence, and analysis through its investments, conferences, and publications. Headquartered in San Francisco, the company oversees a global network of offices throughout the United States, Latin America, Europe, and Asia. For more information visit: www.burrillandco.com.
Daniel Levine
Managing Director
Burrill & CompanyEmail Contact
Daniel Levine
Managing Director
Burrill & CompanyEmail Contact
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Brand Label: Re Done
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About StartPage
StartPage (www.startpage.com) combines the powerful search results of Google with the strong privacy features of Ixquick, the world's most private search engine. The result is great search results - with total privacy protection!
No IP addresses are stored, no personal data is gathered or passed on to third parties, and no identifying cookies are placed on your browser. StartPage also offers secure SSL encryption, a proxy option that allows anonymous web surfing, full third-party certification, and numerous other privacy features.
Company History
The Ixquick search engine was developed and launched in 1998 by David Bodnick in New York. In the year 2000, it was acquired by Surfboard Holding B.V, a privately held Dutch corporation whose only activities are operating Ixquick, and now Startpage. Since its inception in 1998, Ixquick has grown steadily, primarily as a result of word-of-mouth referrals. A number of awards have contributed to our growth, including:
- European Privacy Seal awarded by certifying authority Europrise
- Awarded best metasearch by Search Engine Watch in 2000, 2002, and 2004
StartPage and Ixquick, have steadily increased in popularity since becoming the first search engines dedicated to privacy in 2006. As of December 2013, StartPage and Ixquick had served over 3.7 billion searches. Since January 2012 our traffic number increased with over 400% to an average of well over 4,5 million searches per day.
The StartPage Name
StartPage was released in 2009 in the United States as a new name for the Ixquick search engine. Because the name Ixquick can be somewhat difficult to remember and spell, people asked us for an easier name, and we were happy to oblige. StartPage uses Ixquick's search methodologies and privacy features, and is governed by the same privacy policies.
StartPage has the industry's leading Privacy Policy:
- No recording of users' IP addresses.
- No identifying cookies.
- No collection of personal data.
- No sharing personal data with third parties.
- Offering secure, encrypted connections (HTTPS/SSL)
- And a free proxy service that allows anonymous browsing of websites.
Further details can be found on our Privacy page or in StartPage's Privacy Policy.
Privacy Background
The internet contains immense amounts of information that gives us unprecedented access to shopping, news, entertainment, and more. Search engines help us navigate all of that data to find what we're looking for quickly and efficiently. This convenience hasn't come without a price, however. A serious potential danger associated with the use of search engines is the loss of privacy.
In 2005, StartPage's parent company, Ixquick, undertook an audit to identify the company's liabilities. One shocking finding was that we had collected a huge amount of privacy-sensitive information on our users. Like other search engines, we had stored things like people's search terms, the times and dates of their visits, what links they had chosen to click on, their IP addresses, and their user ID cookies. The technical reasons for collecting the data were simple, and unfortunately widespread in today's IT environment: "It doesn't cost much, it's very easy to do, and the data may come in handy in the future".
Use Private Information
As we looked at that mountain of data, however, it began to look like more of a privacy liability than a business asset. We had never sold the information or used it commercially. Since we are an independent company focused solely on search, we were not interested in combining user data with other services we offer. In sum, we had a database full of user details we neither needed nor wanted.
Use Private Information
"We asked ourselves why we are storing all that privacy-sensitive information, and we realized there was no good reason for it"
That realization took the company in a bold new direction, and from that point forward we made protecting our user's privacy our number one priority. In June 2006, we purged our database and retroactively deleted all IP addresses and other stored search data. We began deleting all new IP addresses within 48 hours. And starting in January 2009, we stopped recording IP addresses at all.
We have now optimized our search processes to guarantee privacy and ensure that we never collect personal data on our users. We also work to ensure that user search data is not collected by other parties. We are the only leading search engine to offer Secure Socket Layer (SSL) or HTTPS encryption to prevent search queries from being eavesdropped on by Internet Service Providers (ISPs) or unscrupulous WiFi providers and hackers. In recognition of this unique feature, StartPage's parent company, Ixquick, received the first European Privacy Award from EU Privacy Commissioner, Mr. Peter Hustinx, in July 2008.
Our business model hinges on excellent search capabilities combined with complete privacy.
Going forward, StartPage will continue to offer innovative privacy-enhancing features and services.
Our Proxy service allows users to visit third-party websites anonymously through StartPage's servers without being tracked by those websites. And we are also exploring ways to offer a truly safe email service. As the Internet continues to evolve, StartPage will stand by its commitment to privacy.
Great search results
StartPage is enhanced by Google, offering the powerful Google search results many people have grown accustomed to. Google's advanced search capabilities are powerful and allow users to dig deeper into the Web. Adding the privacy of Ixquick is what makes StartPage truly special.
Independent Company
StartPage is owned by a privately held corporation, Surfboard Holding, BV, so it is completely independent of outside forces that might seek to exploit user data. StartPage and Ixquick are not affiliated with any national or international organization, corporation, commercial enterprise, government, or intelligence agency. Of course, StartPage would be obligated to comply with legal demands for information from proper government authorities, but because we have no personal information on file, there would be no data to deliver. Maybe that's why StartPage and Ixquick have never been subpoenaed for any user data.
Our Team
From our inception, the company has strived to stay small and flexible and to maintain the creative and innovative spirit of our founder, David Bodnick. We have offices in three countries, with staff and volunteers in the Netherlands, the US, and India. Website management, administrative, and financial work is mainly done from the Netherlands; technical architecture from New York; while our group of highly skilled software engineers in New Delhi, India, take care of most of the site's maintenance and development.
Currently, the management team consists of David Bodnick, our company's founder and technologist; Dr. Katherine Albrecht, who handles US media relations and marketing initiatives for StartPage; Robert Beens, Managing Director; Sally Page, Vice President of Operations; and Alex van Eesteren, Vice President of Marketing and Sales. Our growing arrays of servers are located in Amsterdam and Haarlem in the Netherlands as well as in Palo Alto, New York and Miami in the USA.
Surfboard's competitors are search engines offering similar search services to those offered by Startpage. We operate in the larger search field where Google of course is the household name that holds the lion's share of the search market, along with Yahoo and Bing. When it comes to privacy there are other players we don't consider competitors though because we are jointly trying to raise the level of global privacy awareness. StartPage and Ixquick are the only search engine worldwide to offer fully secure, third-party certified private Web search.
StartPage is a privately held company, so we do not report financial information. We can report that we are fiscally sound and have been profitable for the last five years. To facilitate the user experience, StartPage has opted for a clean and simple user interface with a minimum of advertisements. Some result pages show relevant sponsored results which are clearly indicated at the top of the page and limited to three sponsored results per page. The presentation of these ads has been carefully thought through to safeguard user's privacy, and at no point does StartPage ever share personal user data with any third party.
StartPage's profitability enables us to invest heavily in software development and further privacy enhancements.
Search engine privacy is a very important topic, even more so after the astonishing revelations by Ed Snowden in 2013. For 2014 and beyond, StartPage expects to continue expanding its privacy services which are in large demand. StartMail will offer a reliable encrypted web-mail service. Many other privacy-enhancing products are under consideration. We believe StartPage is a tremendous resource, and we are proud to offer an excellent search resource that protects privacy to the Internet Community.
"We believe StartPage is a tremendous resource."


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Thread: 2001 E46 M3 cost to maintain
2001 E46 M3 cost to maintain
Hey roadfly,
My names chris and I'm 22, I'm really considering buying an 2001 M3 but I'm curious to know the pros and cons of this car such as an good downpayment, cost to maintain, Gas, ETC. The help would be nice please reply especially people who actually own this car.
- Location
- San Mateo, CA, United StatesMember No: 24397
- Join Date
- Jan 2002
- Posts
- 5,074
- Rep Power
- 22
I have an '01 build early '02. Same car.
I keep a basic budget spreadsheet, which includes money I spend on gas, insurance, and my car (in the form of routine things, and repairs, and other stuff I might buy for the car).
I put about 22k miles on my car last year. Average gas cost was 14.4 cents per mile (gas alone). Mostly highway miles, and generally averaging about 23mpg. When I was last on Laguna Seca, I averaged about 9.5mpg... The car has a good electronic engine management system, and how you drive will alter your mileage significantly.
I spent $4567 in maintenance and repair last year on this car. That includes my registration of around $250 per year as well. This also includes 2 tires that I had to buy to replace one with a hole; and another that was really too warn down to leave mismatched (~$500 for the 2 tires total). The rest was repairing a few little issues including portions of an Inspection II service (valve adjustment), a basic tuneup that I did myself (plugs, belts, 1 new coil because the one I removed was not in good condition, etc), high pressure Power steering line needed to be replaced, a small oil return check valve in the block was leaking oil and I replaced that, and I had a leak in one of the throttle body boots, so I replaced all 6 of those. I change the oil every 7500 miles; oil and filters. The oil isn't cheap, around here it runs about $16 per quart. If I plan ahead I usually buy it online for about $11 per quart, plus shipping.
In that time, I also purchased the aluminum interior trim kit to replace the horrid painted stuff that was peeling and cracking badly. I think that kit was around $800.
In '09, I spent around $3900. But that included 4 new tires, at nearly $1k, a used suspension kit for around $800, and a set of used wheels for $1k. Damn... I sound cheap when I re-read that, buying all that used stuff. Oh well :)
In '08 my cost was $2800 for the year, and that was only routine services. Including the Rear Trailing Arm Bushings which go out fairly routinely if not reinforced. This causes the rear toe to go out and wears out the tires prematurely. Also leads to obvious handling issues as well.
It might be worth noting, I have tracked my car a few times. But, by some crazy thing, I have the original brake rotors (at min wear points now, need to be replaced), only on the second set of pads (still easily 8 to 10mm thick), and I still have 40% on my original clutch (6-speed).
My car needs an AC overhaul, the AC is completely out. It's the second time since buying this car in '01 that I have had to service it. My shift lever has too much play in it lately, I need all new bushings there. For the first time ever, when I shifted hard from first to second near redline, quickly; it ground ever so slightly. It could just be the shift mechanism bushing I mentioned earlier, or I suspect the transmission synchro for 1-2 might be going out. At 136k miles I wouldn't be too hopping mad if the tranny were starting to show some age, honestly.
In summary, the car can be purchased for a great price today. However, you need to consider that repair costs and parts are for a $45k+ car. It's not inexpensive to maintain this car. Oil changes cost right around $100. Tires are going to run you between $160 and $300 each, depending on your taste in tires. A brake maintenance, pads and rotors, is right around a grand. Checking my records back, it looks like I average right around $3400 per year in maintenance costs; and add to that about 14 cents a mile in gas, depending on how and where you are driving.
Hope this helps.
Re: 2001 E46 M3 cost to maintain
I believe that cost to operate per year will vary significantly depending on how you're using it. I've only put 34K miles on my 2004 but that's because I only use it on weekends or for the occasional trip. My expenses are limited to insurance, about 4K miles worth of fuel, one oil change, and registration. When I replaced the tires at 25K miles it was about $1200. I don't recall what the brakes cost to replace but I remember it being a significant cost.
Right now there are many e46 M3s on the market for a good price but keep in mind that these cars if driven as a daily driver can require some serious investments for regular maintenance. These cars were just under $60K when taken home from the dealer and parts costs are definitely in-line with that.
You should get some quotes on insurance before buying. I remember how horrible my insurance was before I turned 25 and can't imaging that an M3 registered to a 22 year old is going to come at a discount.
Good luck.
- Location
- San Mateo, CA, United StatesMember No: 24397
- Join Date
- Jan 2002
- Posts
- 5,074
- Rep Power
- 22
Hope to count you amoung the owners!
It's one of the most fun, refined feeling cars I have ever driven. Anymore, the power is good, but no longer remarkable, but it's still fast! It's the naturally aspirated, fat torque, that makes this thing deceptively fast for a 3.2L. Some of the best cars at the same price point are today still only just as fast. You can get a mustang to go faster in a straight line, but it's not the same thing.
beware, not saying "don't do it," just beware
BMW's, and E46 M3's in particular are "high maintenance."
Early E46 M3's had exploding engine problems. 2001's came with 5W-30 synthetic oil. They called everybody back in and switched them to 10W-60. But, the early 2002's started blowing up even more often. They eventually admitted there was a problem and changed out the connecting rod bearings and oil pumps. They later came back and changed out the connecting rod bearings a second time.
BMW's VANOS (variable valve timing) systems are problematic. If they go out of warranty, it's $4k to $5k. Cat' converters are another BMW problem.
Trim in another BMW problem. A lot of people have had window gaskets come loose, painted interior trim fall apart, floor mats, and the dreaded self-dimming rear view mirrors (see my thread below). I had the assembly that contains the rear tag lights and trunk switch break loose.
E46 M3's have solid valve lifters which require adjustemnt during "inspections." Inspections are required every 20k - 28k miles, depending on how you drive (based on MPG). Adjusting the valves requires a collection of shims and special tools. My last inspection was $1,300.
I've kept accurate maintenance and cost records on my car (an early 2002 with 88k miles). I've spent $8,142 on maintenance and repairs. Depreciation is the big one. My car's depreciated $42,667 during that time.
As a car gets older, the depreciation costs (per year or per mile) go down, and the maintenance costs up. Depreciation is a function of time and mileage. An older BMW's value is more dependent on mileage than a newer one's is.
I'm driving it less now (6-8k miles/year), then when it was new (12k miles/year). So, my total cost per mile (depreciation, maintenance, gas, insurance, capital costs (interest the money tied up in the car would have earned) has been very consistant, about $1/mile. My five year old, 83k mile Honda Accord has cost about $0.40/mile. My four year old Cobalt, about $0.37/mile (big deprecation, much higher than the Accord). The last year of my banged up Civic's life, it cost less than $0.20/mile.
I'd stay away from a high mileage E46 M3. I'd also look for one that has had in-between-oil-changes oil changes (about every 7k miles instead of the scheduled 13-14k miles). If you can find a low mileage one with good original paint, and you can tolerate $1/mile and the occasional $2k to $5k surprise, a lot of good ones are out there.
You set off an alarm when you mentioned a "good down payment." If buying a ten year old M3 requires a car loan... DON'T DO IT!!!! Relative to your income and net worth, the car could eat you alive. BMW's, either new or well maintained old ones, are cars for people with six-figure incomes. Otherwise, the car owns you instead of the other way around.
Expensive cars attract vandals, too. If you don't have a garage, safe parking at work, and a beater for trips to Walmart and the mall, it's not worth owning one.
- Location
- Inland Empire, CA,Member No: 139273
- Join Date
- Apr 2006
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- 350
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- 13
mine'll have 4 bald tires & inspection @110k miles
The struts will be toast then, too. I figure I'll find it a good home a few k-miles before then. I'm dialing back my driving now to make it last another three years.
I'm not sure what will replace it. The short list right now is a 911, a M-B E530 Blue TEC, or... my 2007 Cobalt.
There might be a window for me to retire later this year. If so, I'll take it, ease up on luxury purchases, and take time to smell the roses. But, if I'm working for another five or six years, I'm commuting in style... and smelling my boss's [Oops!] for a while instead of roses. (My old boss actually did stink. Fortunately, the new one has better hygene.)
- Location
- Mountain View, CA, United StatesMember No: 103022
- Join Date
- Mar 2004
- Posts
- 72
- Rep Power
- 0
AWESOME post goatboy. thanks for that and dead on.
Anyone buying an M3 should be doing it for love, going in knowing it is an expensive car to buy and maintain. I have a 2002 M3... absolutely LOVE it, but it is *expensive.* Would absolutely do it again, but I can afford it. When I was your age I was driving Preludes and Celica GTS... but if you have the $$$ it is one of the best all-around cars on the road.Reply With Quote 22.214.171.124
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At Shmoop HQ, we get a little giddy over literature and history. Imagine our excitement when it hit us that this year's Martin Luther King, Jr. Day (commemorating MLK's 80th birthday) is also Edgar Allan Poe's 200th birthday. Synchronicity. To mark this doubly-historic date, we lovingly put together these resources about two of our favorites – the spooky story-teller and the inspiring civil rights leader.
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- MLK biography
- Shmoop's fresh coverage of the Civil Rights Movement in the U.S.


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With the 9.0 version of PeopleSoft, new and upgraded features have been added. Faculty-specific information is available for using these new capabilities.
The Registrar's Office is offering training sessions on some of the newer features being delivered with the 9.0 LOUIE Upgrade. Below is a link to the listing of those sessions by day, along with a brief description of each class. Please distribute this information to others in your area who may be interested in attending these sessions over the next two weeks (Deans, Chairs, Faculty, Administrative Staff, etc.). , so please sign up early. If demand is high, we'll definitely look at extending these training sessions as needed.
Registration for these sessions will be available through the ITS Learning and Professional Development office. You may also view these sessions through this training link.
If you have any questions or concerns, please don't hesitate to contact the Registrar Business Analyst team at email@example.com.
Training Schedule for PeopleSoft 9.0-Word Format
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In the shadow of Sept. 11, the question was bound to be asked: who is ensuring the safety of the nation's food? The answer is 12 agencies under both USDA and FDA are using 35 laws while guard-dogging the produce.
Further, there are only 175 inspectors covering 300 U.S. ports of entry far too few to check all imported food items. In a recent report, the General Accounting Office (GAO) says barely 2 percent of imports are inspected. The few inspections that do take place, says the report, are "inconsistent and unreliable."
In numerous reports stretching back decades, the GAO has repeatedly warned that despite spending billions of dollars on food safety, America is woefully unprepared for a looming crisis.
If someone deliberately plants a hideous disease in food destined for U.S. tables, it won't just be consumers who suffer. Processors, retailers, marketers and markets would undoubtedly be hard hit.
Even without terrorism, the national Centers for Disease Control and Prevention (CDC) in Atlanta says despite spending $1 billion annually to prevent it, some 325,000 Americans are hospitalized and another 5,200 die yearly as a result of food contamination.
For these reasons, the current bulky yet undermanned system is not acceptable, say several politicians currently pushing bioterrorism legislation. Representatives Marion Berry, D-Ark., and Greg Ganske, R-Iowa, along with Senators Edward Kennedy, D-Mass., and Bill Frist, R-Tenn., have introduced bills asking for a solid, streamlined infrastructure to coordinate federal, state and local response efforts. The bills, claim their authors, take into account not only food safety but also investments in public health systems and pharmaceutical stockpiles.
"Since the events of Sept. 11th, we have learned that bioterrorism represents a severe threat to our national security and domestic tranquility," Berry said. "This legislation comprehensively addresses that threat and ensures we are prepared as a nation to respond."
The Berry-Ganske Bioterrorism Preparedness Act (H.R. 3310) calls for $3.2 billion to finance the comprehensive effort.
If passed, what would the legislation mean? The act would mean far more qualified personnel including food inspectors and lab technicians on the look-out, a far better ability to track food, and grants for vaccine development.
"The Bush Administration has indicated its support of the legislation, and many lawmakers from both parties have signed on as co-sponsors," Berry said. "Everyone agrees that this nation needs to prepare for the bioterrorism threat, and this bill presents the best way to accomplish that."
E-mail: [email protected]


text:
Friday, December 22, 2006
Varsity Centre Bubble Now Inflated
The new Varsity Centre bubble has now been inflated over the University of Toronto football field on Bloor Street. Students have been looking forward to this event for some time: it means they can now play Ultimate Frisbee all winter.
The press release talks exclusively about athletics but we all know the real reason for creating such a large, heated enclosure. In Canada, the gyms and arenas are stuffed with desks and chairs at this time of year and used for exams.
Rumor has it that the bubble is energy efficient. It recycles a lot of the hot air generated on campus.
2 comments :
- Mustafa Mond, FCDFriday, December 22, 2006 12:13:00 PM
it means they can now play Ultimate Frisbee all winter.ReplyDelete
The name of the sport is simply Ultimate. Frisbee is a registered trademark.
I'm assuming all that hot air is coming from first year philosophy students?ReplyDelete
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text:
O'FALLON, Mo. (AP) - A Missouri woman has paid a $100 fine for calling 911 to report her dog had collapsed.
The St. Louis Post-Dispatch reports that Rose Lakey of O'Fallon referred to the Great Dane as her "daughter" when she made the emergency call on Easter Sunday. She said Wednesday - the day she paid the fine - that the word "daughter" came out accidentally.
Regardless, Lakey was accused of misusing 911. After initially pleading not guilty, Lake decided to dispose of the municipal charge.
Lakey and her husband had just finished walking the 140-pound dog, Oreo, when the animal collapsed. She said she called 911 in a panic. Emergency workers helped get Oreo to an animal hospital, but the dog died.
(Copyright 2012 by The Associated Press. All Rights Reserved.)


text:
English 102:
Freshman Composition
Section 46
Spring 1999
The University of Mississippi
Department of English
Unless otherwise noted, all
information posted in this course website is
Copyright © 1999 by John B. Padgett.
Permission is granted to quote from original copyrighted material for academic purposes only.
For all other uses, send inquiries to email@example.com.
This page was last modified
on .


text:
Celebrating illustration, design, cartoon and comic art of the mid-20th century.
Friday, August 14, 2009
Science + Industry = ... what exactly?
Yes science is an essential part of industry. Why, if the scientists back in 1,000,000 B.C. hadn't done the research of rolling a log down a hill we'd all still be riding on dinosaurs like Alley Oop.
In the critical area of Research and Development, scientists do the research that uncovers new materials and processes, and industry takes those discoveries and develops them into products we can all use.
So its fun to look back half a century and see how industry imagined the world of "the future". A world built on scientific research packaged for a society of consumers -- our world.
Just what did all those R&D dollars give us anyway?
Flying chairs? Nope.
Flying saucers? Nope.
Flying buses? Nope.
Beer in cans? Yes!
And let's face it folks, if you've got beer in cans, what else do you really need?
* A brief history of the beer can.
* My Industry Flickr set.
13 comments:
Bubbly thing= model of a molecule.ReplyDelete
Beer in cans is very much a mixed blessing: I lived in Saskatchewan when that was introduced and the discarded aluminum cans damn near buried the landscape shortly afterward.
Tom Palmer sent the following email which he has given me permission to post:ReplyDelete
Today's Inspiration really caught my eye, especially the "Philadelphia Electric" multi-panel ad, the large panel and each of the others in the complete ad has the famous model, Steve Holland, posing in them. He's the scientist with glasses in the large detail panel, the guy on the right of the two in front of a panel board, and the guy above a glowing cauldron, etc.
If you don't know already, Steve Holland has to be the most ubiquitous model ever, illustrators used him for men's adventure illustrations, ads, and especially paperbacks, most notably, the Doc Savage series that Jim Bama illustrated. Bama probably used him the most overall and they were good friends. Frank Reilly had him come in to pose for photo shoots when we were doing class projects and he made an enormous professional impression on all of us.
I had the good fortune to use Steve as a model on many occasions in my career and found him to be not only one of the nicest and generous people I've met, but his acting skills that he used in posing made every shot perfect and you could cover a great deal of ground in an one hour session or less. He made a perfect model for Captain America by the way!
Really miss him!
Best regards,


text:
2013 Annual Meeting
Montréal, Québec, Canada | November 1-5, 2013
Jordan Boyd-Graber, University of Maryland
Kimberly A. Glasgow, University of Maryland
Jackie S. Zajac, University of Maryland
Monday, 1:30pm
Spoilers---critical plot information about works of fiction that ``spoil'' a viewer's enjoyment---have prompted elaborate social conventions on social media to allow readers to insulate themselves from spoilers. However, these solutions depend on the contentiousness of Internet posters and are thus an imperfect system. We create an automatic alternative that could alert users when a piece of text contains a spoiler. An automated spoiler detector serves not only as an additional protection against spoilers, but it also contributes to important problems in computational linguistics. We develop a new dataset of spoilers gathered from social media and create automatic classifiers using machine learning techniques. After establishing baseline performance using lexical features, we develop metadata-based features that substantially improve performance on the spoiler detection task.


text:
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text:
It's hard to describe the world's famous snowboarder. But to put it in nutshells: this rider is the icon of a sport, the rider who had possibly the most influence on a sport which progressed in the last years like a rocket launched to outer space.
It all began in 1986 when Shaun Roger White was born in San Diego, California. And the first months on earth didn't seem to be the ones of a super star decorated with X-Gmes Gold in skateboarding and snowboarding both won in the 2003, plus the Olympic Halfpipe Gold medal in 2006 and 2010 everyone expected him to bring home.
Before he was one year old, White endured two major surgeries to correct a heart defect.
Thereafter, the growing youngster quickly charged into surfing and snowboarding.
He took his first snow turns aged six when his mom Cathy had decided to put him on a snowboard in order to slow him down as Shaun had been racing down the slopes with his older brother Jesse on skis prety fast before.
However, that move didn't slow him down.
The seven years-old kid entered his first ever amateur competition, won and earned a wildcard for the nationals which he finished just outside the top-10.
After his mom had send a homemade video to Burton just as the brand was developing a kid-sized snowboard line, he got the company interested in him and became a pro at 13.
Ever since, an outstanding career started in which Shaun White became a role model for freestyle snowboarding not only making him the most successful rider of the last decade although he had missed the 2002 US Olympic rooster by only three tenths of a point.
He also pushed - and still does - the scene to the limits by inventing new tricks in the halfpipe like the back-to-back double cork 1080's or by revealing the double mctwist 1260 in an online video filmed in his private $ 500,000 halfpipe built by one of his sponsors in the Rocky Mountains - only about a month before the 2010 Olympics.
This also is the best proof for him having a nose for promoting himself. He has signed several major deals with worldwide operating brands; he has his own signature outerwear line which has been expanded since 2003 into gloves, boots, boards and bags as well as into women outerwear.
The leader of a deep US team who has more than 32,500,000 hits when searching the web for the redheaded athlete stars his own video game and impressed with covers on Sports Illustrated and Rolling Stone in the same week.
The young face of numerous advertising campaigns once said: "I'm not the underdog anymore. I have the pressure that everyone expects something outstanding. Everyone expects me to do the best." And so the world will at the 2014 Sochi Games. Just like in 2006 and 2010, once again, nothing more than Gold, in both halfpipe and slopestyle.
In order to be best-prepared for this, White and his sponsors once again built a private pipe worth some $ 500,000 in the Australian ski resort Perisher - this time, it didn't pay off... White placed fourth. But you never know what he might come up with over the next couple of years. It's pretty likely that he gives it another shot in 2022 in South Korea.


text:
In no particular order
Ongoing Series
One Piece
Hunter x Hunter
Hajime No Ippo
The World God Only Knows
Cage of Eden
Completed Series
20th Century Boys and 21st Century Boys
Midori No Hibi
Rurouni Kenshin
Any Mitsuru Adachi manga
There are probably others I'd interchange with the ones on this list but these are the ones that come to mind now.
AKB49: Renai Kinshi lourei (Cool and interesting)
Air Gear (awesome!)
Akumetsu (Holy Fu!)
Wolf Guy: Ookami No Monshou (Holy Fu!)
Ao No Exorcist/Blue Exorcist (Cool)
Berserk (Legend in my eyes)
Dragon Zakura (Awesome in its own way)
Full Metal Panic! (good)
Onani Master Kurosawa (easily On my top 5)
Vagabond (Seams to be good)
Usagi Drop (Awesome)
one piece
black lagoon
sayonara zetsubou sensei
welcome to the nhk
Ok, so after some VERY painful eliminations I think I finally got my list….
1. D. Gray man ( One of the best ongoing manga in my opinion , when a new chapter came out I literally jumped off my couch and ran around the room like an idiot)
2. Kuroko No Basuke (I first looked the manga series up after my obsession with ep.1 and I've even started a fanfic on it too!)
3. Kuroshitsuji (The art is amazing along with the most intriguing arcs, I absolutely LOVE this one)
4. Pandora Hearts (This is such a good manga when it comes to plot, twist, and angst!)
5. Witch Hunter (Absolutely got hooked on this by the 5th chapter)
6.Defense Devil (I love the characters and the twists and turns in this!)
7.Undertaker Riddle (I got hooked on the characters, plot, and it even has very small hints shonen ai)
8.Mother Keeper ( It really is a tearjerker and has a very good plot)
9.Are You Alice? (It really plays with the characters mind, as well as your own and it'll have your head turning in every direction with these twists!)
10.En Passent (It's a short series but it has action, mystery, comedy, school, the supernatural and it'll have you crying tears of joy at the end!)
11.Makai Ouji-Devils and Realists (Not only is the main character a noble with the highest grades in his class, but he can also communicate with demons!)
Bold is ongoing
Red is a MUST read
Skip Beat
Marmalade Boy
Kodomo no omocha
Detective Conan
Welcome to the NHK
Atashi wa bambi
Haruhi Suzumiya
ᕙ(͡°‿ ͡°)ᕗ
Zen Martial Arts Academy
Hajime No Ippo
The Breaker
The God Of High School
Eyeshield 21
Akame Ga Kiru
Surprised that no one has mentioned Yotsubato (aka Yotsuba&!). Probably the funniest manga I've ever read.
Just some of my favorites (: must read ones
I put labels them in categories..
1. Naruto-action,comedy,&adventure
2. Blue exorcist-action&comedy
3. No.6-Sci fi& hints of BL
4. Nisekoi-School love & mystery
5. Deathnote-Mystery,Adventure,&violence
6. Shugo Chara-adventure&comedy
7. Freezing-action,sci-fi,ecchi
8. Full metal alchemist-action&comedy
9. The One-mystery
10. Elfin Lied-mystery&violence
11. Kingdom Hearts-Sci-fi,mystery,comedy,&action
fk, gone
11 mangas? what a pain I have to eliminate some of my fav mangas. But finally I got 11 titles, list is not in order.
1. Vagabond
Wanna see Miyamoto Musashi as a rebel youngster? This is about Musashi's journey to become the invincible under heaven. This manga has a lot of great quotes and philosophy about life.
2. Beelzebub
I can't stop laughing when I read this manga. It's about a school thug that have to raise a demon king's child. The baby is absolutely cute but have an extraordinary power.
3. Slam Dunk
Really entertaining manga. Good sense of humor, great plot, interesting characters, and good graphic. But the ending is kinda rushed. Doesn't matter. I love this manga. Highly recomended!
4. Flower of Evil (manhwa)
The story is about a twin (boy and girl), who used to do things that behave like a couple. So this manhwa has incest story (if you don't like incest story or mentally not ready, don't read this). It really is a psycho, tragic, and mental-abusing manhwa.
5. Death Note
You know? About a genius honor student who found a death god's death note and use it to clean up the world from the criminals. Anyone whose name is written in that book will die within 60 seconds. And you can decide how the victim dead.
6. Yanki-kun to Megane-chan
Really funny manga about an ex-delinquent student who wants to be a honor student. But she can't really achieve that title because of her stupidity.
7. Fuan no Tane (and Fuan no Tane Plus)
Some horror story in a manga. It contains a really short story (about 3-5 pages each) but quite thrilling. Mostly about daily strangeness we rarely to notice and Japanese folk horror story.
8. Let Dai
A good and different shounen-ai story. Not cliche, good plot, complicated conflict, and I love it.
9. Ao Haru Ride
A sweet romance story about a girl and a boy who like each other, but got seprated due the boy's family problem. Finally they meet again in high school. And some feelings aren't the same anymore.
10. Cat Street
A romance story about an ex-artist who trying to move on after her best friend betrayed her. She meets some unique people in a cool school and be friends with them. And a love triangle story will follow. Not cliche love story for me.
11. Hideout
A lot of disturbing scene. About a writer who have a broken family, and wanted to kill his annyoing wife. When they wanted to start a "new beginning", they stucked in a weird cave, and everything will never be the same after that. A short horror story.
Red: ongoing
Green: completed
So many titles.... I'm too lazy to list 11 so here are 3 excellent ones:
≡ Black Jack
≡ Nausicaä of the Valley of the Wind
≡ Kurosagi Corpse Delivery Service
My top 11 are as follows (not in any particular order, and most are still ongoing):
These are GREAT for a good laugh!
1.) Lucky * Star (Pure moe and ADORABLE, as well!) -Unfortunately, the English release of this series has been cancelled with the downfall of BANDAI Entertainment in North America... The first 8 volumes are out, however, and they're DEFINITELY worth reading! And, of course, the series is still ongoing in Japan for those of you who can read Japanese. Volume 9 was released at the end of last year.-
2.) K-ON! (Again, pure more and adorable...) -First part of the series is complete and has been released in North America...-
3.) GinTama (Also a good action series...)
And these are my shounen action series of choice! (Sure, most of them may be completely mainstream, but popular series are popular for a reason, right ?...
6.) Rurouni Kenshin -COMPLETED-
7.) Beelzebub (Can also be good for a laugh, as well...)
8.) Fullmetal Alchemist -COMPLETED-
9.) InuYasha -COMPLETED-
10.) Usagi Drop -Bunny Drop- (A more realistic type of story that's also incredibly cute!) -Completed, but not yet fully released in North America...-
11.) Gin no Saji -Silver Spoon- (Basically, more along the lines of a slice-of-life comedy... Good for a laugh.)
Send me your 3DS Friend Codes! Playing Pokemon Omega Ruby and Smash Bros.!!
1.akame ga kiru
4.Watashi ni xx Shinasai!
5.medaka box
6.code breaker
7.witch hunter
Initial D
Ghost in the Shell (not SAC, just Ghost in the Shell. Only 2 volumes out so far).
Battle Royale
Eternal Sabbath
Skip Beat
Cowboy Bebop: Shooting Star (Original manga that the anime and Cowboy Bebop manga was based off of).
Black Lagoon
GTO: Great Teacher Onizuka
Black Butler
Fullmetal Alchemist
Chasing kitties.
Dragon Ball
One Piece
Death Note
Sailor Moon
Full Metal Alchemist
Detective Conan
Katekyo Hitman Reborn
Love Hina
Deadman Wonderland
One piece
Bleach ( only the rukia rescue arc. bleach starts good but ends bad)
Cowboy bepop
Feel free to chat with me.


text: American Learning Corporation has appointed Dr. Glenda Baskin Glover as a new member of the board of directors. She is a certified public accountant, an attorney and finance administrator and educator. Glover is currently the dean of the College of Business at Jackson State University. She was previously the chairperson of the Department of Accounting at Howard University. Her previous ...Read More »


text:
Matt B needed a new logo design and created a contest on 99designs.
A winner was selected from 102 designs submitted by 19 freelance designers.
The Cremation Society of Connecticut is an inexpensive alternative for those who wish to choose cremation. This will be our new logo.
Cremation Society of Connecticut
We want a logo that is professional and dignified. One that will be used for display on websites and print media. It should be able to be printed in both full color as well as black and white. It should attract attention so that members of the community take note of the service and know that it is available.
The Name: Cremation Society of Connecticut
Color scheme: we like blue, but we are not wed to anything.
Imagery: Something that highlights our New England location and demonstrates reliability. I was thinking a lighthouse, but again, feel free to be creative.
We would like a style that is contemporary, but elegant.
- Too many colors
- Overtly modern fonts
- All capital letter
- Anything that may be viewed as in bad taste.
- Any caskets, tombstones, hearses, etc.
Find out how a design contest works or learn more about our logo design services.