text:
With less than two weeks before Christmas, the Rolla Police Department is trying to prove that it's not too late to help out those in need this holiday season.
With less than two weeks before Christmas, the Rolla Police Department is trying to prove that it's not too late to help out those in need this holiday season.
After learning that local food banks are in extremely low supply this year, RPD staff decided to do their part in collecting goods for families in need this time of year.
More than 10,000 users like the RPD Facebook page and the RPD is hoping that each fan can bring in one non-perishable item to be donated.
For fans of the page who don't live in town, if they know of someone from the Rolla area, they can have those individuals bring in an item on their behalf.
Even if not all 10,000-plus fans participate, if half of the fans brought in two items each, the RPD could reach its goal.
Among the items needed are canned goods, dry goods, toilet paper, cat food, dog food, kitty litter and toothpaste among other non-perishable items.
The dog and cat food and supplies will be provided to needy families who have pets.
For about $5, you can supply a food bank with approximately 10 cans of food.
Non-perishable items can be brought to the RPD lobby 24 hours a day, seven days a week. Donations will be accepted until noon Monday, Dec. 17.
People who would like to donate but cannot bring items may contact Detective Derrick Dillon at 573-308-1213 and the department will arrange to have their items picked up.
Dillon said the donations collected at the RPD will be given to Denny Ford, who will distribute to area food pantries.
"We're using Denny Ford as a reosurce to get the items to the pantries," Dillon said.
"We have a close-knit family here so when we hear about a need like this, we step up," said Sgt. Vince Giacolone.
People who donate at the RPD can sign up on a clipboard in the lobby for a chance to win a small giveaway.
Any person who brings in items will be eligible for the drawing.


text:
July 6, 2008
Third Sunday After Pentecost
Father Pat's Pastoral Ponderings
Because it appears first in his corpus--and is the longest of his letters--I suppose it is natural to begin studying St. Paul by reading Romans.
I want to suggest, nonetheless, that there is a serious problem--perhaps even a theological danger--in taking this approach, especially if it involves (as often is the case) using Romans as the master key to the interpretation of Paul as a whole. Perhaps the best way to identify this problem is to describe the defining characteristics of the Epistle to the Romans:
Romans is unique in the amount of attention given to what we may call phenomenological anthropology. That is to say, no other New Testament work goes to such lengths to describe the experience of living as a human being. Romans represents, in short, Paul's most extensive and mature reflection on the human condition.
There were apparently two germinating seeds that found rich fruit in that reflection: Paul's conversion (ca. 32) and the Galatian crisis (ca. 53).
First, there was Paul's experience of conversion. In the overpowering light revealed on the road to Damascus, he recognized, not only Jesus as Lord, but also himself as a deeply sinful man, someone at enmity with God: "Why do you persecute Me?" Until that point, where the searing truth of his condition was made manifest to him, Paul had imagined himself to be the Lord's faithful servant, a loyal adherent of the Law, and a man pleasing to the Most High by reason of that adherence.
After the revelatory experience of his conversion, however, Paul knew that he had been deceived. He realized, in a radical way, that his very adherence to the Law had caused him to fancy himself a righteous man. That is to say, the Law had not only failed to justify him before God; it also proved to be the occasion of his offending God.
In sum, the Apostle's conversion revealed to him, not only the lordship of Jesus, but also his own sinful state and the disadvantage of the Law.
Second, there was the Galatian crisis, in which Paul had to contend with the Judaizers, those who professed the observance of the Law as obligatory for Christians. Paul understandably examined and criticized that profession from the perspective of his conversion, and, in doing so, he adjusted the theological rudder that would guide the future history of the Church.
The crisis in Galatia laid bare two opposing views of salvation history. The Judaizers regarded the latter solely in term of continuity. Although they apparently accepted Jesus as the fulfillment of prophecy, they did not regard Him as also the fulfillment of the Law--in the sense of rendering superfluous the future observance of the Law.
Paul, however, whose experience of conversion was marked by a deep sense of "before and after," was disposed to look at salvation history from the same perspective--a before and an after. The first covenant, that of the Law, was symbolized in Abraham's elder son, Ishmael, the child of the slave girl. The covenant of the Gospel, on the other hand, was expressed in Isaac, the child of Sarah, the son of promise. These covenants were distinguished as representing two stages in history, divided by what Paul called "the fullness of time" (Galatians 4:4-31).
Between the writing of Galatians and the composition of Romans in early A. D. 58, Paul had had almost five years to think more deeply on the content of that earlier epistle. In particular, he had reflected on the anthropological implications of its thesis: justification by faith apart from the works of the Law. He deeply explored the psychology of man with and without Christ. This is the reason why Romans lays such immense stress on phenomenological anthropology, the experience of human existence with and without divine grace. This existential and psychological preoccupation is usually taken to be the chief characteristic of the Epistle to the Romans.
I want to suggest that it also poses the major difficulty of using Romans as the key to understanding Paul's theology. To put the matter simply, the existentialism of Romans presupposes an ontological basis of redemption, to which Paul gave greater attention in his earlier letters, notably the Macedonian and Corinthian literature. Inasmuch as these works laid greater stress on the objective work of Christ, I suggest they serve as better introductions to Paul's theology--his soteriology in particular. Otherwise, there is a danger that an anthropological preoccupation may overwhelm and dominate Christology in the study of Paul.
Indeed, as St. Paul has been interpreted throughout history, one may observe several instances in which the Christological center of soteriology has been displaced by considerations of religious psychology. It is easy to document, I believe, that some readers of Paul, taking Romans as their interpretive key, have reduced Christology to a mere subcategory of anthropology. They forgot that the letters to the Thessalonians and Corinthians (and, it seems to me, Philippians) were written before Romans. Romans should be unlocked with the key of those earlier letters, not the other way around.

subset: commoncrawl


text:
GameXplain: "The GameXplain crew talks about what little we know of The Legend of Zelda U, including what it will play like, how multiplayer might work, how the Gamepad might be taken advantage of, and much, much more!"
I really like these gamexplain videos. I hope they keep doing them.
They made some good points.
Also, good to see someone else notice the great voice acting in Fire Emblem games. Like I have been saying that series is what gives me confidence in Nintendo's ability to use full voice acting for a Zelda.
Again, if they do use voice acting please keep the fuzzy-squeaky-voiced-JarJar Binks-character's dialogue to a minimum.
Thank You
I'm hoping the gameplay be similar to Skyward Sword


text:
A nice article in Globe and Mail. A random quote:
"We have learned so much about language and learning to read. The same thing needs to happen with math," said Dr. Ansari, who notes that for every 14 studies on how children learn to read, only one is done on how they grasp math. Dyscalculia is as prevalent as dyslexia, a learning disorder that makes it hard for children to master reading, Dr. Ansari said. But parents, teachers and educational professionals have far less awareness about it.
[with thanks to Dennis Lomas]


text:
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text:
What is Acuvail?Acuvail discount prices start at just $309.87!
Commonly Used Brand Name(s)Acular, Acular LS, Acular PF, Acuvail, Bromday, Bromsite, Ilevro, Nevanac, Ocufen, Prolensa, Voltaren, Xibrom, Apo-Ketorolac, Ratio-Ketorolac, Vofenal, Voltaren Ophtha
- Overview
- Proper Use
- Dosing
- Missed Dose
- Use & Storage
- Allergies
- Pediatric
- Geriatric
- Pregnancy
- Breast Feeding
- Drug Interactions
- Other Interactions
- Other Medical Problems
- Precautions
Ophthalmic anti-inflammatory medicines are used in the eye to lessen problems that can occur during or after some kinds of eye surgery. Sometimes, the pupil of the eye gets smaller during an operation. This makes it more difficult for the surgeon to reach some areas of the eye. Some of these medicines are used to help prevent this. Also, some of them are used after eye surgery, to relieve effects such as inflammation or edema (too much fluid in the eye).
These medicines may also be used for other conditions, as determined by your ophthalmologist (eye doctor).
This medicine is available only with your doctor's prescription.
Proper UseTOP
To use:
- First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye.
- Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, always keep the container tightly closed.
Do not use this medicine more often or for a longer time than your doctor ordered. To do so may increase the chance of side effects.
Do not use any leftover medicine for future eye problems without first checking with your doctor. If certain kinds of infection are present, using this medicine may make the infection worse and possibly lead to eye damage.
The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- To treat photophobia (sensitivity to light) which may occur after incisional refractive surgery:
- Adults—Your health care professional will probably give you the medicine before the operation, starting with 1 drop in the eye within one hour of surgery, then 1 drop fifteen minutes after surgery, then 1 drop four times a day beginning four to six hours after surgery and continuing for up to three days as needed.
- Children—Use and dose must be determined by the doctor.
- To relieve inflammation in the eye following cataract surgery:
- Adults—1 drop in the eye four times a day beginning twenty-four hours after cataract surgery and throughout the first two weeks following the operation.
- Children—Use and dose must be determined by the doctor.
For diclofenac
- For use before an eye operation:
- Adults—Your health care professional will probably give you the medicine before your operation.
- Children—Use and dose must be determined by the doctor.
- To relieve inflammation:
- Adults and children—Use and dose must be determined by the doctor.
For flurbiprofen
- For use before an eye operation:
- Adults—Your health care professional will probably give you the medicine before your operation.
- Children—Use and dose must be determined by the doctor.
- To relieve inflammation or edema in the eye:
- Adults—1 drop in the eye four times a day.
- Children—Use and dose must be determined by the doctor.
For indomethacin
- For use before an eye operation:
- Adults—Your health care professional will probably give you the medicine before your operation.
- Children—Use and dose must be determined by the doctor.
For suprofen
Missed DoseTOP
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Use & StorageTOP
Keep out of the reach of children.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Do not keep outdated medicine or medicine no longer needed.
Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
These medicines have been studied only in adults, and there is no specific information about their use in children.
These medicines have been tested and have not been shown to cause different side effects or problems in older people than they do in younger adults.
Although studies on birth defects have not been done in pregnant women after use of these medicines in the eye, ophthalmic anti-inflammatory medicines have not been reported to cause birth defects or other problems. Studies have been done in animals receiving anti-inflammatory medicines by mouth in amounts that are much greater than the amounts used in the eye. These medicines did not cause birth defects in these studies. However, they decreased the weight or slowed the growth of the fetus and caused other, more serious, harmful effects on the fetus when they were given in amounts that were large enough to cause harmful effects in the mother. Also, when these medicines were given to animals late in pregnancy, they increased the length of pregnancy or prolonged labor.
Breast FeedingTOP
It is not known whether any of these medicines pass into the breast milk after they are placed in the eye. Diclofenac, indomethacin, and suprofen pass into the breast milk when they are are taken by mouth. It is not known whether flurbiprofen passes into the breast milk when it is taken by mouth. However, these medicines have not been shown to cause problems in nursing babies.
Drug InteractionsTOP
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.
- Aceclofenac
- Acemetacin
- Amtolmetin Guacil
- Aspirin
- Bromfenac
- Bufexamac
- Celecoxib
- Choline Salicylate
- Clonixin
- Dexibuprofen
- Dexketoprofen
- Diclofenac
- Diflunisal
- Dipyrone
- Droxicam
- Etodolac
- Etofenamate
- Etoricoxib
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Floctafenine
- Flufenamic Acid
- Flurbiprofen
- Ibuprofen
- Indomethacin
- Ketoprofen
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Meclofenamate
- Mefenamic Acid
- Meloxicam
- Morniflumate
- Nabumetone
- Naproxen
- Nepafenac
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Oxaprozin
- Oxyphenbutazone
- Parecoxib
- Pentoxifylline
- Phenylbutazone
- Piketoprofen
- Piroxicam
- Proglumetacin
- Propyphenazone
- Proquazone
- Rofecoxib
- Salicylic Acid
- Salsalate
- Sodium Salicylate
- Sulfasalazine
- Sulindac
- Tenoxicam
- Tiaprofenic Acid
- Tolfenamic Acid
- Tolmetin
- Valdecoxib
Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abciximab
- Acenocoumarol
- Anagrelide
- Apixaban
- Ardeparin
- Argatroban
- Bemiparin
- Betamethasone
- Bivalirudin
- Budesonide
- Cangrelor
- Certoparin
- Cilostazol
- Ciprofloxacin
- Citalopram
- Clopidogrel
- Cortisone
- Dabigatran Etexilate
- Dalteparin
- Danaparoid
- Deflazacort
- Desirudin
- Desvenlafaxine
- Dexamethasone
- Dipyridamole
- Duloxetine
- Edoxaban
- Enoxaparin
- Epoprostenol
- Eptifibatide
- Escitalopram
- Feverfew
- Fluocortolone
- Fluoxetine
- Fluvoxamine
- Fondaparinux
- Ginkgo
- Heparin
- Hydrocortisone
- Iloprost
- Lepirudin
- Levomilnacipran
- Meadowsweet
- Methotrexate
- Methylprednisolone
- Milnacipran
- Nadroparin
- Nefazodone
- Paramethasone
- Parnaparin
- Paroxetine
- Phenindione
- Phenprocoumon
- Prasugrel
- Prednisolone
- Prednisone
- Protein C
- Reboxetine
- Reviparin
- Rivaroxaban
- Sertraline
- Sibutramine
- Ticagrelor
- Ticlopidine
- Tinzaparin
- Tirofiban
- Treprostinil
- Venlafaxine
- Vilazodone
- Vorapaxar
- Vortioxetine
- Warfarin
Other InteractionsTOP
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical ProblemsTOP
The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:
- Hemophilia or other bleeding problems—The possibility of bleeding may be increased.
- Viral eye infection (epithelial herpes simplex keratitis), or a history of having a viral eye infection—It is possible that a current infection could be made worse or an old infection could return.
- Use of soft contact lenses—Eye irritation, such as redness and burning of the eyes, may occur.


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These organisms actually
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often should I use this
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I use this on my pets,
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While Paraway Plus is
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Gruenwald J, Brendler T,
Jaenicke C. Physician's
Desk Reference for
Herbal Medicines.
Medical Economics
Company, Inc. 1998.
The Lawrence Review of
Natural Products. Facts
and Comparisons, a
Wolters Kluwer Company.
Blumenthal M. The
Complete German
Commission E Monographs,
Therapeutic Guide to
Herbal Medicines.
American Botanical
Council. 1998.
Schulz V, Hansel R,
Tyler VE. Rational
Phytotherapy: A
Physicians Guide to
Herbal Medicine.
Heidelberg, Germany.
2001 Parasites and
Resources. Ohio State
University, College of
Biological Sciences.http://www.biosci.ohio-state.edu/~parasite/home.html
* These statements have
not been evaluated by
the Food and Drug
Administration. These
products are not
intended to diagnose,
cure, treat, or prevent
any disease.
* These
statements have not been evaluated by the
Food and Drug Administration. These products
are not intended to diagnose, cure, treat,
or prevent any disease.


text:
Write a News Story
Meet a Pioneer Pilot
Amelia Earhart Home
Back to
Story List
Amelia Earhart's Last Flight
By: Norman S.
Alabama, Age 15
Ameila was an overachiever. She was the first woman to fly solo, and now she did that she wanted to take it up a step and fly around the world. It was in a custom made Lockheed Model 10E Electra with her navigator Fed Noonan, that she began the attempt.
On May 21, she left Oakland, CA, and proceeded to fly across the country, staying over land as much as possible. They touched down in Miami, FL for a refuel, then left again, touching down occasionally in places such as San Juan, enegal, Africa, and Calcutta, India.
After leaving Lae, New Guinea, she headed for Howland Island far off in the Pacific Ocean. However, she never arrived.
She surely will go down in history as a famous aviator surely.
Back to
Story List


text:
The limbless, primarily soil-dwelling and tropical caecilian amphibians (Gymnophiona) comprise the least known order of tetrapods. On the basis of unprecedented extensive fieldwork, we report the discovery of a previously overlooked, ancient lineage and radiation of caecilians from threatened habitats in the underexplored states of northeast India. Molecular phylogenetic analyses of mitogenomic and nuclear DNA sequences, and comparative cranial anatomy indicate an unexpected sister-group relationship with the exclusively African family Herpelidae. Relaxed molecular clock analyses indicate that these lineages diverged in the Early Cretaceous, about 140 Ma. The discovery adds a major branch to the amphibian tree of life and sheds light on both the evolution and biogeography of caecilians and the biotic history of northeast India—an area generally interpreted as a gateway between biodiversity hotspots rather than a distinct biogeographic unit with its own ancient endemics. Because of its distinctive morphology, inferred age and phylogenetic relationships, we recognize the newly discovered caecilian radiation as a new family of modern amphibians.
1. Introduction
The ca 185 described extant species of caecilian amphibians (Gymnophiona) are concentrated in tropical regions of mostly Gondwanan origin. Like other amphibians, the limbless, mostly soil-dwelling caecilians have limited capacity for dispersal across salt-water barriers and are therefore expected to be useful in investigating vicariance in continental-scale biogeography. Additionally, because the distribution of modern caecilian lineages is highly regionalized [1] and almost entirely restricted to the wet tropics, the contemporary presence of caecilian lineages in a region can provide evidence of a long history of wet tropical environments in that region. Thus, our discovery of an ancient radiation of caecilians from northeast India prompts a re-evaluation of the biogeographic history and significance of this area.
The latest family-level classification of caecilians [1] recognized nine monophyletic, morphologically distinct and ancient (more than 60 Ma old) families. Only two of these families have representatives in Asia and both are thought to have reached Asia through continental drift by rafting on the Indian plate. The entirely Asian Ichthyophiidae dispersed 'Out of India' into southeast Asia [2]. By contrast, the teresomatan (i.e. non-rhinatrematid and non-ichthyophiid, or tail-less caecilians) Indotyphlidae has 12 species in the Western Ghats biodiversity hotspot in peninsular India [1,3,4] and only one poorly preserved and badly damaged specimen from Assam, northeast India, described in 1904 [5]. Our recent investigations of the caecilians of northeast India reveal the latter to be member of a previously unknown, yet widespread, radiation of teresomatan caecilians that is morphologically distinct from indotyphlids and more closely related to the African family Herpelidae than to any other caecilians. We propose that this radiation be recognized as a distinct new family.
2. Material and methods
During 2006–2010, we conducted, to our knowledge, the most extensive dedicated caecilian surveys ever attempted and the first in northeast India, comprising 1177 person-hours of digging soil at 238 localities. Vouchers were fixed in 4 per cent formalin and stored in 70 per cent ethanol, with tissue samples (liver and/or muscle) of representative specimens stored in absolute ethanol. Three main molecular phylogenetic analyses (using maximum likelihood and Bayesian inference) were carried out with various taxon and character sampling regimes; (i) representatives of all major caecilian lineages, including a single northeast Indian teresomatan, sequenced for the complete mitochondrial (mt) genome and the nuclear genes rag1 and slc8a1; (ii) representatives of all major caecilians, including 10 northeast Indian teresomatans from all major mt haplotype clades sequenced for mt cox1 and 16S; and (iii) 43 northeast Indian teresomatans sequenced for mt cox1 and 16S. Divergence times were estimated using a Bayesian relaxed clock method and all possible combinations of up to three calibrated nodes. Cranial osteology of four northeast Indian teresomatans was investigated using high-resolution X-ray computed tomography (voxel size 10 μm). Diagnostic cranial features were confirmed by gross dissection in single members of the other major mt haplotype clades. See the electronic supplementary material for detailed methods.
3. Results
More than 500 teresomatan caecilians were encountered at 58 of the 238 localities surveyed (see the electronic supplementary material, table S1), including, to our knowledge, the first teresomatans discovered from the states of Arunachal Pradesh, Meghalaya, Nagaland and Tripura (figure 1). Phylogenetic analyses of a large dataset of DNA sequence data comprising complete mt genomes and two nuclear markers reveal that these caecilians are more closely related to the African Herpelidae than to the Indotyphlidae and that they and the Herpelidae diverged about 140 ± ca 20 Ma (figure 2). Morphologically, the northeast Indian teresomatans differ from indotyphlids in having perforate stapes and separate premaxillae and nasals (figure 3), and lack the multiple antotic foramina that diagnoses the Herpelidae [1]. Thus, we recognize the northeast Indian teresomatans as a distinct, tenth family of caecilians.
Amphibia L., 1758
Gymnophiona Rafinesque, 1814
Stegokrotaphia Cannatella & Hillis, 1993
Teresomata Wilkinson & Nussbaum, 2006
Chikilidae fam. nov.
Chikila gen. nov.
Etymology. Chikila is a northeast (Meghalaya state) Indian tribal name for the included caecilians.
Type species. Herpele fulleri Alcock, 1904.
Diagnosis of family and genus. Caecilians that, like herpelids (Boulengerula and Herpele), have perforate stapes and no septomaxilla, but which differ from herpelids in having a single (undivided) antotic foramen on each side, frontals that do not contribute to the roof of the braincase posterior to the sphenethmoid and carotid foramina posterior to the crista marking the anterior limit of the insertion of the ventral trunk musculature onto the os basale (figures 3 and 4). They further differ from Herpele in lacking separate pterygoids, and from Boulengerula in retaining separate premaxillae and nasals, secondary annuli and annular scales. Additionally, Chikila are oviparous with direct development, lack prefrontals and have two rows of teeth in the lower jaws.
Phylogenetic definition. All caecilians more closely related to Chikila fulleri than to Herpele squalostoma.
Distribution. Chikila is a small but widespread radiation of relatively common caecilians in the northeast Indian states of Arunachal Pradesh, Assam, Meghalaya, Nagaland and Tripura (figures 1b and 5a). DNA barcoding of 43 individuals from 38 localities spanning the known range of the genus reveals it to be a monophyletic, multi-species radiation of as many as seven strongly supported, allopatric mt haplotype clades (figure 5b).
4. Discussion
Herpelidae comprises exclusively African caecilians whose distributions include the Eastern Arc (Boulengerula) and the Guinean Forests of West Africa (Herpele) biodiversity hotspots. Our timetree (figure 2) indicates that the divergence between Chikilidae and Herpelidae could have been caused by the separation of India from Africa 165–121 Ma [6]. By contrast, for a 'Gondwanan group' [7–9], it is striking how little signature of Gondwanan fragmentation is carried in the pattern and timing of other divergences between major caecilian lineages. In particular, the five oldest divergences appear to be independent of tectonic vicariance, and lead to several regionally restricted ancient lineages: rhinatrematids (South America), ichthyophiids (Asia), scolecomorphids (Africa) and caeciliids + typhlonectids (South America). Thus, if our timescale is correct, the caecilian fauna of Gondwana was markedly regionalized, and continental fragmentation largely reinforced spatial partitions rather than caused them.
Our analyses indicate that caecilian history is mostly characterized by the long persistence of geographically restricted lineages with limited dispersal and low net rates of speciation. Modern caecilians are mostly restricted to wet tropical regions, a constraint we interpret as suggesting that the presence of ancient caecilian lineages is an indicator of a continuous history of spatio-temporally connected wet tropical environments in that region.
Our discoveries indicate that Chikilidae was present in Greater India (Madagascar–India–Seychelles or Indigascar [10]) during isolation and northward drift of this landmass. However, the oldest divergence among extant chikilids probably occurred after India accreted with the rest of Asia ca 65–42 Ma [11] (figure 2). Many plant and animal groups that experienced isolation in Greater India are nowadays endemic to the Western Ghats–Sri Lanka biodiversity hotspot, suggesting that part of this mountain range acted as a refugium during the massive Deccan Traps volcanism around the Cretaceous–Tertiary (K–T) boundary [12]. The absence of chikilids in peninsular India and of any peninsular Indian indotyphlids (Gegeneophis, Indotyphlus) in northeast India suggests that both lineages radiated within their respective regions, potentially isolated by the Deccan Traps that separated these regions in the Early Cenozoic [13].
This in situ radiation of Chikilidae, combined with the apparently low rates of caecilian dispersal as evidenced by observed present and inferred past regionalism, is strongly suggestive of long-term relative environmental stability within northeast India. This identifies northeast India as an overlooked candidate unit in biogeography, containing a richer fauna than would be expected from a 'gateway' [14] lying between the Himalaya and Indo-Burma hotspots, and serving as a second refugium for fauna and flora during Cretaceous isolation of the Indian subcontinent. The Western Ghats is part of a relatively well-studied biodiversity hotspot [15]. By contrast, and as our research highlights, northeast India is very poorly documented and not well understood. Thus, although India is a recognized centre of global amphibian diversity and endemism [12,16] having more endemic families than any other country [17], this endemism has hitherto been documented only from the Western Ghats.
As well as having important implications for understanding amphibian evolution, the discovery of an endemic family of vertebrates, to our knowledge the first for northeast India, identifies this as a region with a potentially rich but still hidden biodiversity in need of improved inventories and robust phylogenies (currently lacking) of other taxa. If northeast India indeed harboured a special fauna and flora around the K-T transition, this region is likely to reveal more hidden treasures in the near future. Further explorations and conservation actions are urgent because the region's biodiversity is generally under high threat from the growing resident human population1 and rapid deforestation [18].
The research was supported by funding from the University of Delhi (support to faculty for strengthening R&D programme); DBT, Government of India; IUCN/ASG/SSC (lost amphibian species of India, 2007); The Percy Sladen Memorial Fund, The Linnaean Society, London to S.D.B; Critical Ecosystem Partnership Fund, Conservation International, USA; The Royal Society and Indian DST (to S.D.B. and D.J.G); Direct Senior Research Fellowship, Council of Scientific & Industrial Research (CSIR), India (9/45 (1082)/2011-EMR-I to R.G.K); European Union Marie Curie Mobility and Training Programme (PIEF-GA-2009-237658 to D.S.M.); Natural Environmental Research Council studentship (NE/F009011/1 to E.S.); European Research Council (Grant 204509, project TAPAS, to F.B.); the Fonds voor Wetenschappelijk Onderzoek Vlaanderen postdoctoral fellowship (FWOTM573 to I.V.B.). Forest departments (Arunachal Pradesh, Assam, Manipur, Meghalaya, Nagaland, Tripura and West Bengal) provided study permits to S.D.B.
↵1 Between 1961 and 2001, the human population in northeast India grew by a whopping 24 million (Census of India, retrieved from http://censusindia.gov.in/), an increase of ca 0.6 million people per year. This excludes the population of three districts of West Bengal viz. Cooch Behar, Jalpaiguri and Darjeeling, which are considered as part of the biogeographic part of northeast India.
- Received January 22, 2012.
- Accepted February 2, 2012.
- This journal is © 2012 The Royal Society


text:
Veselin Tasev is a Bulgarian DJ and producer. He is the most productive name on the Bulgarian trance scene, and his productions have brought him success in Europe and the United States. He is an artist with own label; TCD Recordings. In the early 90's, Veselin Tasev started working with Steve O - producer at the music company "JOE" – Sofia, which has contracts with music labels such as Hitland-Italy; Time-Italy; Dancework-Italy; ZYX-Germany; Media Records-UK and others. From 1992 to 2001, Tasev produced several CD compilations of music hits for major international companies, including MTel, a Bulgarian mobile operator.
He has sold more than 500,000 mix productions. Veselin Tasev can be defined as an EDM Producer and DJ and he works with styles as Tech House, Progressive House, Progressive Trance, and Uplifting Trance. In Bulgaria he also works with music styles like Pop, House, Progressive House, Progressive Trance and Uplifting Trance.
Veselin Tasev has three radio shows; Digital Trance World, Trance Culture and Danse Avec Moi. The show that gives him the greatest popularity as a Trance DJ is a Digital Trance World broadcast exclusive on Afterhours.FM. In the beginning in 2014, Digital Trance World was broadcast to nearly 300 listeners. He is also a Resident DJ on several other radio stations: Party107-USA, 1 Mix Radio-UK, Discover Trance Radio-UK, Radio Hi-Tec-Holland, TDP Radio-Belgium, Pulse Radio-Australia and Puresound.FM-Russia..
In May 2007, Veselin Tasev founded the first Bulgarian Trance label - TCD Recordings.
He was personally approved by the No1 DJ in the world for 2005 and 2006, Paul van Dyk, to support his gig in Sofia, part of World Tour 2009.
He played at parties along with many famous DJs like Paul van Dyk, Markus Schulz, Ferry Corsten, Aly& Fila, Chicane, Andy Moor, Ronski Speed, Cosmic Gate, Sander van Dorn, Menno de Jong, Pedro del Mar, Fast Distance, Cor Fijneman, Stoneface & Terminal, Mr. Pit and others.
Veselin Tasev's tracks are supported by:
Armin Van Buuren, Ferry Corsten, Markus Schulz, Sean Tyas, Aly & Fila, Adam Nickey, Fast Distance, Tom Colontonio, Ronski Speed, Roger Shah, Pedro del Mar, Suzy Solar, Manuel Le Saux, Jorn van Deynhoven, Philippe El Sisi, Claudia Cazacu, Ehren Stowers, Reorder and others.
In February 2010, his newest single "Pacific Waves" was included in the CD compilation "LAS VEGAS 10", presented by Markus Schulz (Armada Music).
In April 2010, "Pacific Waves" was included in the CD compilation "Global DJ Broadcast Top 15" (Armada Music)
In February 14th 2011, released newest single "Desire" by TCD Recordings and was included in the CD compilation "MELOMANIA 20" (Black Hole Recordings) presented by Pedro Del Mar.
In December 15th 2011, released newest single "Blue Light 2011" by TCD Recordings and was included in the CD compilation "MELOMANIA 21" (Black Hole Recordings) presented by Pedro Del Mar.
10th May 2012 is memorable for Veselin Tasev; the number one DJ Armin Van Buuren broadcast on his popular show ASOT episode 560 and support the new song Veselin Tasev "Sant Rafel de sa Creu (Original Eivissa Mix)". A long-awaited moment and recognises his work as a producer and DJ in the world. Again, on 17-05-2012 Veselin Tasev "Sant Rafel de sa Creu (Original Eivissa Mix)" was played on ASOT episode 561 and Top 5 Future Favorite ASOT 561.
Contracts with record company:
2012 A State Of Trance (Holland)
2012 Shah Music (Germany)
2011 Black Hole Recordings (Holland)
2011 Black Hole Recordings (Holland)
2010 Armada Music (Holland)
2010 Armada Music (Holland)
2009 Klubbstyle Records (Germany)
2007 Bonzai Music (Belgium)
Veselin Tasev "After Sunset" 7 place in the Top 100 Trance Tracks TrackItDown-UK
Veselin Tasev "Blue Light" 9 place in the Top 100 Trance Tracks JunoRecords-UK
Veselin Tasev "Pacific Waves" 3 place in the Top 100 Trance Tracks Armada Music , AudioJelly and JunoRecords-UK
Veselin Tasev "Desire" 5 place in the Top 100 Trance Tracks UK JunoRecords
Veselin Tasev "Sant Rafel de sa Creu (Original Eivissa Mix)" 3 place in the DJ Tunes Top 100 Trance
Paul Adams "The Green Valley (Veselin Tasev Remix)" 10 place Uplifting Trance Chart Top 50 Germany
2008 - DJ Mag-Top 100 DJ's (World)
2009 - DJ Mag-Top 100 DJ's (World)
2010 - DJ Mag-Top 100 DJ's (World)
2011 - DJ Mag-Top 100 DJ's (World)
2012 - DJ Mag-Top 100 DJ's (World)
2013 - DJ Mag-Top 100 DJ's (World)
2009 - SeeMe Awards 2009 (East Europe)
2010 - SeeMe Awards 2010 (East Europe)
2009 - Trance Awards 2009 (World)
Best South-East European Trance DJ at SEE-Me Festival 2010
Web Sites:
http://www.discogs.com/artist/Veselin Tasev
2. EDM Producer
3. Psychologist / Master – Psychology (Social Psychology) 2004 High Education
Contact: +359892989863
Ricardo Vaccarini Str. 10A
Sector "B" Floor "3" Apartment "6"
P.O. Box 6/B
Sofia City
1404 Sofia
Remember Me


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Reviewed By Ryan P (Spencer, IN) Reviewed for a 2008 Dodge Durango —11/28/2012 7:23 AM
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text:
|2006-05-30, 10:45
|Link #41
Gomen asobase desuwa!
Join Date: Nov 2003
Age: 37
Translated, that line becomes: "Here here oni-san, follow the clapping hands"
Obviously, this is a metaphor for Higurashi's storyline. It is an excellent way to portray the "blindness" of the mystery in a village that is rumored to have demons dwelling within it, and how the viewer can only rely on what is given.
|2006-05-30, 15:22
|Link #43
Join Date: May 2006
Location: where Grudge is Greatest, Rancour Endless and Malice Eternal(at school^^;;)
When the vocal is bad just focus away from the lyrics, set your mind on /ignore mode, and treat the voice like some other instrument you don't understand. Then it's usually not too bad.
|2006-05-30, 16:53
|Link #44
trainee archangel
Arimfe : Problem is, what should I do if I don't like the voice either.
|2006-05-31, 02:47
|Link #45
I don't mind the song actually, the relaxing tune normally suits my mood after watching one of the episodes (in a kind of 'need to relax after all that' way) but yeah, the singing is meh. It reminds me somewhat of the vocal song they used in the .hack//GU trailers... if anyone heard the E3 2005(?) trailer version, it was originally in English and, well, crap. By TGS they clearly realised it didn't work, and they changed it to Japanese but with the same tune. I love it now Shame the B-side to the single probably won't be a Japanese version though.
|2006-05-31, 09:13
|Link #47
Join Date: Dec 2005
Location: Kino's luggage
|2006-06-01, 23:01
|Link #49
Give me things to draw!!!
Here are lyrics to the vocal version of "you". I might go around translating it later, if I have time. I've never written out song lyrics before, so please tell me if I have done anything wrong.
Kanji version:
今まで私の心を埋めていたモノ 失って初めて気づいた
もう一度あの頃に戻ろう 今度はきっと大丈夫
いつもそばで笑っていよう あなたのすぐそばで・・・
Romaji version:
Anata wa ima doko de nani wo shiteimasu ka?
Kono sora no tsuzuku basho ni imasu ka?
Ima made watashi no kokoro wo umeteitamono Ushinatte hajimete kizuita
Konna ni mo watashi wo sasaete kuretaita koto Konna ni mo egao wo kureteita koto
Ushinatte shimatta daishou wa totetsu mo naku ookisugite
Torimodosou to hisshi ni Te wo nobashite mo gaku keredo
Marude kaze no you ni suri nukete todokisou de todokanai
Kodoku to zetsubou ni mune wo shimetsukerare kokoro ga kowaresou ni naru kedo
Omoide ni nokoru anata no egao ga watashi wo itsumo hagemashite kureru
Mou ichido ano koro ni modorou Kondo wa kitto daijoubu
Itsumo soba de waratteiyou Anata no sugu soba de
Anata wa ima doko de nani wo shiteimasu ka?
Kono sora no tsuzuku basho ni imasu ka?
Itsumo no you ni egao de ite kuremasu ka?
Ima wa tada sore wo negai tsuzukeru
Last edited by Rasuberi; 2006-06-02 at 19:39.
|2006-06-02, 01:26
|Link #51
This is my ____ face
You Translation
What are you doing now, at what place?
Are you at a place where this sky continues into?
I lost that which has buried my heart until now and noticed it for the first time
The fact that you had been supporting me this much
The fact that you had been giving me smiles this much
The price of having lost it is way too preposterously great
And I desperately reach out my hands and struggle to recover it, but-
It slips by just like the wind; it looks like I'll reach it but I don't
My chest is tightened by loneliness and despair and my heart seems to break
But your smiling face that remains in my memories always encourages me
Let's return to that time again; I'm sure that you'll be all right this time
I'll always laugh by your side, right by your side...
What are you doing now, at what place?
Are you at a place where this sky continues into?
Will you be there with a smile like always?
Now I simply keep wishing for that
EDIT: Thanks, Sushi-Y
Last edited by Li Jianliang; 2006-06-02 at 21:04.
|2006-06-10, 19:02
|Link #53
This is my ____ face
Lyrics to Nakanai Kimi to Nageki no Sekai - bewailing
Nakanai Kimi to Nageki no Sekai (You who Don't Cry and the World of Bewailing)
Song used in the music video:
Vocals: Shinra Etsuko
悲しみと 痛みだけ
忘れても 消せなくて
変わらずに 輝いて
壞しても 待ってる
悲しみも 痛みさえ
あぁ またひぐらしと夏の薫り
無くしても 消えなくて
Kizukeba Warai naita ano hibi ga
Modosenai mono ni barabara ni sarete
Uso to uso o kasaneta dake no
Kanashimi to Itami dake
Tsukimatou higurashi to natsu no kaori
Wasurete mo Kesenakute
Kiesaru basho wa akaku somatteku
Shiranu man ni chikazuku oto ga kitateru
Kirisakarete ita omoide dake
Kawarazu ni Kagayaite
Kono yuugure no nageki no naka ni
Kowashite mo Matteru
Nukeochite mienaku natte iku
Kanashimi mo Itami sae
Aa Mata higurashi to natsu no kaori
Nakushite mo Kienakute
If you'd notice, those days when we laughed and cried
Have been scattered into pieces of something unrestorable
Only the sadness and pain
Of just having one lie stacked on another lie
Even if we forget the cicadas and scent of summer that follow behind
We can't erase them
The vanishing place is being dyed red
Before we knew it, the approaching sound comes
Only my memories that were cleaved apart
Shine unchanged
Within the bewailing of this dusk
Even if I destroy them, you'll be waiting
They are being pulled off and turning invisible-
Sadness, and even pain, too
Ah, even if we lose the cicadas and scent of summer again
They won't disappear
...I'll post the lyrics to Tsuki wa Noboru, Watashi wa Utau (used in Nakanai Kimi to Nageki no Sekai -Soushunfu-) later.
Last edited by Li Jianliang; 2006-07-02 at 15:44.
|2006-06-13, 21:17
|Link #55
This is my ____ face
Is it possible to get the songs from the three Nakanai Kimi to Nageki no Sekai via web orders in U.S.? I'm interested in listening to higher-qualitied versions of the songs rather than the static-ish music from YouTube. ^^;;
Oh, the song to the second video is so sad. I wonder whose point of view the lyrics are from... Mion or Shion? And to whom? Keiichi or Satoshi?
Nakanai Kimi to Nageki no Sekai -Soushunfu- (You who Don't Cry and the World of Bewailing -Early Spring Ode-)
Song used in the music video:
Tsuki wa Noboru, Watashi wa Utau
The Moon Rises, I Sing
Vocals: Shinra Etsuko
悲しみの調べ携えた 白き光
救われぬ 運命の道だけ 照らし出す
気付いたの ほら あなたの手が
触れる度 そう 心揺れてた
話したい こと ふえていくよ
このままじゃ ただ積もるばかりで
忘れられない それが苦しくても
忘れたくない 「せめて」と願う
胸をさす壊れた幸せ きっと戻せない
会えなくて狂いそうだけど この気持ち伝えたくて…
目が合えば すぐ ふざけあって
誤魔化すことで 逃げてしまうの
強くなれない あなた傍にいると
強くなりたい 「せめて」と願う
ワガママでも変われるはず 信じていた
胸をさす壊れた幸せ きっと戻せない
例え、この身すべて偽りでも この気持ち伝えたくて…
二人 心 抱く悲鳴
今は 離れ 涙と共に…
凍えるくらいキレイな 白き光
救われぬ 運命の道だけ 照らし出す
もう届かない 想い儚く
ひぐらしの声だけは あの頃と変わらず 空へ
Kanashimi no shirabe tazusaete Shiroki hikari
Sukuwarenu Sadame no michi dake Terashidasu
Kizuita no Hora Anata no te ga
Fureru tabi Sou Kokoro yureteta
Hanashitai Koto Fuete yuku yo
Kono mama ja Tada tsumoru bakari de
Wasurerarenai Sore ga kurushikute mo
Wasuretakunai "Semete" to negau
Mune o sasu kowareta shiawase Kitto modosenai
Aenakute kuruisou da kedo Kono kimochi tsutaetakute...
Me ga aeba Sugu Fuzakeatte
Gomakasu koto de Nigete shimau no
Tsuyoku narenai Anata soba ni iru to
Tsuyoku naritai "Semete" to negau
Wagamama de mo kawareru hazu Shinjite ita
Sunao na egao de aitai dake na no ni
Mune o sasu kowareta shiawase Kitto modosenai
Tatoe kono mi subete itsuwari de mo Kono kimochi tsutaetakute...
Futari Kokoro Idaku himei
Ima wa Hanare Namida to tomo ni...
Kogoeru kurai kirei na Shiroki hikari
Sukuwarenu Sadame no michi dake Terashidasu
Mou todokanai Omoi hakanaku
Higurashi no koe dake wa Ano koro to kawarazu Sora e
The white light that sadness examines and carries
Only illuminates the unsalvageable path of fate
I've realized, look, that every time when your hands
Touched me, that's right, my heart wavered
Things that I want to tell you increase in number
While I remain like this, they simply accumulate
I can't forget it, even if it's painful
I don't want to forget it "at least", or so I wish
I'm sure that I can't restore the broken happiness that stabs at my chest
I can't meet you and I seem to go mad, but I want to tell you my feelings...
When our eyes meet, I immediately joke around with you
By deceiving you, I run away
I can't become strong if I'm by your side
I want to become strong "at least", or so I wish
I believed that even if I'm selfish, I would still be able to change
Even though I merely want to meet you with an honest, smiling face
I'm sure that I can't restore the broken happiness that stabs at my chest
Even if all of my body are falsehoods, I want to tell you my feelings...
Screams embrace, our, hearts
Now, separate, along with tears...
The beautiful, white light that appears to freeze
Only illuminates the unsalvageable path of fate
My feelings that don't reach you anymore are fleeting
Only the voices of cicadas are unchanged like back then, in the sky
Last edited by Li Jianliang; 2006-07-02 at 15:45.
|2006-06-13, 22:30
|Link #56
Join Date: Dec 2004
Location: Canada
Age: 33
(Each of these CDs included hi and low res versions of the movies, as well as 2 vocal tracks (one of which is used in the movie) + wallpapers)
Now, as for the "static-ish" thing, I can tell you this: that's pretty much what they really sound like. ^^; The only thing I did to compress the audio was converting the original audio source into 160kbps mp3, and as far as I can tell, the YouTube versions sounded pretty much the same as the originals.
I think the problem is with the track themselves (especially "bewailing", because of the intense sound ranges): these aren't the kind of tracks you'd want to play on crappy speakers or headphones, especially if you're the kind of person who likes to crank up the bass and treble settings. ^^; You should try adjusting your speaker or computer audio settings and then try listening to the tracks again. (A good test point would be the "嘘と嘘を重ねただけの (悲しみと) 痛みだけ" part of "bewailing", pay special attention to the cymbals) Both my speakers and headphone replays the audio from the YouTube videos beautifully.
As for the lyrics from Soushunfu, well, they probably describes both Shion and Mion's thoughts, depending on who's on screen at the time (for example, the second segment is the part about Mion (目が合えば すぐふざけあって)).
|2006-06-14, 06:50
|Link #57
Junior Member
Join Date: Jul 2004
Higurashi no Naku Koro ni Image Album - Kakera Musubi (still in production)
大嶋啓之 from Voltage of Imagination. Favours exotic-sounding compositions (...don't like his music much, actually)
Morrigan from "WAVE." Has the ability to compose and arrange in a very wide range of genres. Doujin music god. WAVE already released an ultra quality Higurashi doujin music CD some years back
zts, one of the composers of Higurashi no Naku Koro ni Kai fame
癒月 (Yuzuki-san), who sang the vocals on the "Thanks/you" soundtrack and plays Rena in the doujin radio drama version of Higurashi.
...that is an all-star cast from the doujin music world! Ryukishi-san is going to be working on the lyrics together with Katakiri-san as well. Can't wait for it to come out!
p.s. as long as Katakiri-san doesn't try to sing English/Engrish again...Katakiri-san only has average Engrish, but for some odd reason loves writing and singing Engrish lyrics. Japanese lyrics please! >.<
Updated members:
bermei.inazawa of "studio campanella." Old and well-respected composer.
interface. Lyric writer, works with studio campanella.
綾菓&来兎 of "風葉." ...who? Know nothing about them...
霜月はるかさん (Shimotsuki-san) of "Maple Leaf." Sang the EDs of the two Rozen Maiden series. My favourite singer ever. Like Rekka-san, mostly does professional work these days, but still occasionally cranks out the odd doujin music CD. Voice is perfect for fantasy world genre songs, and improving in other genres.
茶太 (Chata-san) of "茶太屋." Has a voice kinda similar to Shimotsuki-san's, but loves producing weird music. She, Rekka-san and Shimotsuki-san are friends, and are often involved in each other's music.
Last edited by Chaotic_Reign; 2006-06-19 at 02:15.
|2006-06-19, 16:48
|Link #60
Senior Member
I think the main reason the ending theme is sort of not given the respect it
could have is that they placed a phasing effect on the singer making her
unusual english pronunciating even even more strange. Try singing a song
and put your voice thru a phasing effect using something like Cooledit and
you'll see what I mean.
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Execution plans! Don't you just love them? They're the first thing you look at when tuning a query or a stored procedure. But what do you do if you have a gigantic query play with 10's of nodes? how do you find the most complex one? Where do you start?
What I've usually done in situations like that is to first find the node/statement with the highest cost and work from there. Now the highest cost can be IO, CPU, Row number or the good old SubTree cost which gives us a number based on all those counters. Let's see how.
posted @ Thursday, January 21, 2010 12:14 PM | Feedback (11) |
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Adam Machanic launced his second TSQL tuesday: Invitation for T-SQL Tuesday #002: A Puzzling Situation. The theme is to show something interesting and not expected by the first look. You can follow posts for this theme on Twitter by looking at #TSQL2sDay hashtag.
Ok here we go. Let me ask you this: How many times will the subquery in the below SQL statement be executed?
SELECT (SELECT COUNT(*) FROM Sales.SalesOrderDetail WHERE SalesOrderID = SOH.SalesOrderID) AS c, *FROM Sales.SalesOrderHeader SOHORDER BY c DESC
How about the subquery in this in the below SQL statement be executed? It's the same query...
posted @ Tuesday, January 12, 2010 2:05 PM | Feedback (1) |
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SQL Server
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Happy Thanksgiving to all! I absolutely LOVE Turkey Day, more so than any other holiday NOT named my birthday. Screw the gifts and hype of Christmas, Thanksgiving is where it's at in bringing people together. I've been disappointed as a kid on Christmas, but never on Thanksgiving. I spent this morning thinking about what I'm thankful for in Seahawks Land. Of course, I don't expect anyone to actually read this all through. Just a sort of skim and breeze through for those still jonesin' for some Hawks even on Thanksgiving.
It is important on this day to take time out and bring to light the things that one is thankful for. Or so they say. Usually on Thanksgiving, I just like to hang my head in shame while saying sorry to all of the Native Americans out there who got treated like they were Seahawks at a Super Bowl and got the shaft, big time. So without further ado, these are the things that I am thankful for...
Paul Allen: Not only does he own the Seahawks but he loves Jimi Hendrix. Sounds like a great guy to me. Seriously, he saved our team and now he's provided world class facilities, a beautiful state of the art stadium that we can proudly call home, excellent front office and coaching staffs, and the best part... he lets the football people make football decisions. We love you Paul! Thanks!
Doug Baldwin: I am thankful that you broke 2 of your teeth for this football team. If I were out there, I would've done the same. You embody what it means to be a "gamer" and not the Call of Duty kind. Keep working hard and it'll pay off.
Alan Branch: I am thankful for the fact that you do such a thankless job. Your name gets mentioned every once in a while but no where near the amount that Mebane and some of the other cats do. If you were a Stealer, we'd have to listen endlessly about how you "play the game the right way." Your demeanor is soooo "lunch pail" and I respect you for that.
Brandon Browner: Words can not describe what you mean to me. They will never do you justice. So I'll just stop. Thanks for never giving up and always chasing guys down from behind and would-be touchdowns, amongst other things.
Red Bryant: Thank you for being the definition of a leader and for never giving up when things looked bleak for your career way back when. You're like a giant, angry teddy bear and we love you for that. Also, thanks for high-stepping into the endzone last season in Chicago. Loved it.
James Carpenter: Thanks for looking like a rock monster and somehow being on the field this season. I honestly thought I wasn't going to see you for a while. Glad you made it back and look forward to the future.
Kam Chancellor: Thanks for being ONE OF THE HARDEST HITTING SAFETIES IN THE LEAGUE!! All I want for Christmas is for you to make Vernon Davis have to eat his food through a straw for a few weeks afterwards. Simple request.
Chris Clemons: Thanks for not taking plays off after your big payday. Not that I ever thought you would, but, you know. It kinda happens a lot these days. Also, thanks for the big hit on Sanchez with me in attendance. It was a thing of beauty.
Braylon Edwards: Thank you for that wonderful touchdown catch against the Patriots. I'm hoping we'll get to see more of that later this season.
Heath Farwell: You wanna talk about thankless? If you look it up in the dictionary you'll see a picture of Heath. The Heath Bar as I affectionately call him is severely underrated in the grand scheme of things. Thank you for being you, Heath.
Matt Flynn: Thanks for not standing out in the preseason. If you had, we might not have gotten a glimpse of the future. No, but seriously, here's to hoping you find a starting spot somewhere in the near future. Once we find a comparable, cheaper alternative for a backup of course.
Breno Giacomini: Thanks for giving me that one moment a game (sometimes more!) where I get to say "What the hell Breno?!" or "F'N Giacomini, again?!" Your name alone makes you a legend. Your ruthless style of play makes you one of my favorites.
Clint Gresham: I never notice you. My heart thanks you for that.
Winston Guy: Mitt Rooney? Seriously guy? It's all good. Hope your suspension stems from you wanting to beat out Jeron for his job next season. Thanks for the comic relief.
Steven Hauschka: Are you Polish? My Polish buddy always says that you're not. I need to know. I think you are. Thanks for not being Josh Brown.
Leroy Hill: Thanks for defying all logic and every analyst by still being on the team in 2012. You still hit like a freight train and you're one of the Seahawks I'd hate to run into in an alley.
Jaye Howard: Thanks for finally getting into a game this season. May there be many, many more to come.
Bruce Irvin: I'd like to personally thank your mother for naming you Bruce. It makes for a cool thing to yell at a game. Also, thanks for stickin' it to Mel Kiper and co. I am forever indebted to you.
Lemuel Jeanpierre: Thanks for having an amazing name, for allowing me to potentially sound sophisticated while watching the Seahawks at the same time, and for being rock solid whenever your number gets called.
Jeron Johnson: I wish you were a Vandal instead, but I still like you. You have a certain "Je ne sais Babs" air to your play. Thanks for always being around the ball.
Rishaw Johnson: I always think of Rickshaw when I hear your name. You're a big dude. Thanks for not committing accidental homicide on the field, yet.
Jason Jones: If you were a comic book character you'd be called "Metronome Jones." You allow the defense to truly execute exactly what it wants. Please stay healthy. Thanks for picking Seattle.
Jermaine Kearse: I appreciate your sense of humor after that dropped pass against Minnesota. Thanks for the laugh.
Jeremy Lane: At Seafense we're big fans of Jeremy Lane, as you can tell. Nobody seems to want to share their intimate Seahawks moments (I blame it on the Seattle Freeze) but some day I'm sure they will. Thanks for having a name that plays off of "trip down memory lane" so well. Oh, and I'm expecting you'll make a fine nickel or dime corner for us someday.
Marshawn Lynch: You had me at "what it do?" One of my favorite players of all-time. Thanks for being exactly what the Doc ordered after years of yearning for a smash mouth running back. No offense to SA37, but after years of watching Shaun, Marshawn is a refreshing change of pace. I'll never forget where I was for your earth shattering run against the Saints (Carlow East!)
Chris Maragos: Are you Greek? My Greek friend wants to know. Sounds like it. Very well then, thanks for being a demon on special teams and throwing your body around like you want to destroy it. Good times.
Charly Martin: Thanks for collapsing your lung for the good of the team. Bevell really hung you out to dry on that one. Here's hoping you start making some plays like you did in the preseason.
Byron Maxwell: See Chris Maragos, minus the part about being Greek.
Anthony McCoy: Your block in the preseason against Denver was amazing! Thanks for that one. Otherwise, I hate that you have the dreaded "p" word... potential. I'll now give you an insane amount of time to cash in on it before giving up on you completely as a player.
Clinton McDonald: I love that you remind me of Chartric Darby. I wonder what Chartric Darby is doing now? Thanks for guiding my mind down that path, Clint.
Paul McQuistan: Thanks for whatever that is you do with your hair. You not only accept the hair situation, but you embrace it. Seriously though, thanks for playing anywhere needed, at any time. Chris Gray 2.0 and that's a damn good thing.
Brandon Mebane: Me! Bane! Thanks for rewarding my unwavering confidence in you with a mammoth start to the season. I'm so proud of you. Keep up the good work, stud. Pro Bowl? I'm also thankful for the fact that there's a dude at Carlow East who wears your jersey. That's awesome.
Zach Miller: You are the consummate professional. If Kellen Winslow were you, he would've bitched and moaned his way out of town, but you haven't. You've just soldiered up (see what I did there?) and kept on truckin'. I appreciate that and want to thank you for being an excellent 6th Lineman. I get the feeling that sooner or later you're going to break out.
John Moffitt: You seem like the funniest guy on the Seahawks. I like funny. I heard a rumor that your uncle has been to Carlow East and told you about it and that you want to go there one day. That's awesome. Thanks for making it easy to root for you on Sunday's.
Evan Moore: Thanks for not being Kellen Winslow.
Mike Morgan: You flashed some skills in the preseason but you looked like a turkey against the Vikings in relief of K.J. It's okay though, everyone gets their shot at redemption, and you made the most of yours. Thanks for the great play on 4th and 1 against the Jets. Greene never stood a chance.
Ben Obomanu: A loyal servant to the Seattle Seahawks. Thanks for always being classy, Ben. I never thought that you'd last this long when the team drafted you under the Holmgren regime but alas, you've made it. Here's to a quick recovery and a valiant return next season.
Russell Okung: I won't jinx you and say anything about your health. What I will say is that, penalties aside, you've been nothing short of amazing this season. Thanks for putting in the hard work necessary to being on top of your game.
Frank Omiyale: I'll be honest Frank, I thought you were a poor signing and an even poorer selection for the 53 Man Roster. Funny thing though, I love crow! You've been solid as hell whenever needed and that deserves a heaping plate of gratitude.
Mike Person: Thank you for being a real Person. You also graduated from Montana State. There's a guy who comes to my bar who graduated from there. He's cool, so you must be cool too.
Josh Portis: I honestly thought you had a shot at being the Quarterback of the Future. I don't know if that says more about you or me, but whatever. Thanks for giving me that hope with your quarter of inspirational football in a preseason game in San Diego two seasons ago. You looked like Randall Cunnigham.
Sidney Rice: See part about health with Russell Okung. You've stepped up your game this season and good for you. You deserve it. You've been through a lot and the time in the weight room is paying off. Keep it up Sid. Thanks. You are also remarkable at spinning a football.
Michael Robinson: The Real Rob Report helped get me through the off-season. I don't know if I could have done it without you. Wanna talk about thankless job? How about using your body as a battering ram on every single offensive play. Often times taking on the biggest, fastest, or hardest hitting player on the opposing team head on. I'm sure Marshawn and Russell Wilson would say thanks a lot, big fella.
Jon Ryan: What can I say about Jon that hasn't been said before? The Ginger Bomber holds a special place in my heart right alongside the likes of Jeff Feagles and Isaiah Kacyvenski. For some reason, I'm just drawn to the dude. Could be the ginger locks or it could be the monster leg. Or it could be the fact that he's Canadian or the fact that he dove into the pile trying to recover a fumble during the preseason. Whatever it is, thanks Jon.
Greg Scruggs: Coolest athlete ever? Potentially. You asked 12's around the great State of Washington to hang out with you and show you around the city. If that's not cool, then I honestly don't know what is. Thanks for breaking down the 4th wall and being a real person. And for the awesome sack dance.
Steve Raible: Before I was old enough to drink and watch games at bars and before I could watch them at home, I listened to games on the radio while following NFL GameCenter simultaneously. There goes that word again. Steve Raible taught me how to love the Seahawks. His passion for the team and the game is contagious and I love it when he loses his shit. Thanks for the memories, Steve!
Richard "Ringworm" Sherman: Ohhhh Sherman, Sherman, Sherman! What a beast! The only thing more impressive than your meteoric rise to the top of the NFL is your legendary smack talk. You back it up every week, which is no small task. Thanks for reminding me of Muhammed Ali whenever I see you talkin smack out there. It's supposed to be a fun game and you keep it that way, while also layin' the smackdown.
Malcolm Smith: Your tireless work ethic is appreciated around these parts. You've endured a lot to even be in this position. Hopefully you're ready to seize the day when you get a chance to start on this team.
J.R. Sweezy: It ain't easy bein Sweezy! Thanks for punching an elderly man in the face and thanks for turning Tom Cable into a God! The sky's the limit!
Tanzania: Need I say more? I'm thankful for Mount Kilimanjaro and the inspiration it provides our players and fans. I'm thankful for Paul Allen giving a fudge about Tanzania. I'm thankful that the team is undefeated with the Tanzania banner up and especially thankful for the fact that whenever it makes an appearance on screen, something good for the Hawks usually follows. Tanzania All We Got, Tanzania All We Need!
Golden Tate: It's been a rollercoaster ride cheering for you. I loved you at first, then I hated you, then I loved you again, had hope, hated you... good work so far this season. Don't let it get to your head though. There's a ton of the dreaded P word in you, let's tap into all of it! Thanks for hurdling Kyle Wilson on the Jets so that I got to laugh at my friends.
Earl Thomas: You have the speed of a Jedi. You make the insane look routine. Watching you close down on an airborne pass is poetry in motion. A marvel to behold. I'll never get tired of watching you play, Earl. Despite your penchant for dropped interceptions, you are one of the most exciting players on the team. Thanks.
Walter Thurmond III: Thanks for having the balls to rock a high top fade. Seriously, respect. May your return be filled with pass deflections and interceptions.
Marcus Trufant: TRUUUU!!! I should, can, and will write more about you at length at some point because you deserve it. No joking around here, Tru deserves a giant thank you from everybody for all the work he's done with the Seahawks and the State of Washington. If he were a New York Yankee people would be lauding the fact that he's played in his hometown state for his ENTIRE LIFE. Think about that. That's unheard of in this day and age in sports. That's why I was so nervous when he was being courted by the Broncos to play safety. Please, never leave us Tru. Having a solid season as well, really great to see when many thought he was done.
Robert Turbin: I can't wait to watch you fully take off, Turbo. I love everything I've seen so far. I'm hoping that we'll get to see more of you as the season continues, since you'll be relatively fresh in comparison to the defenders that will be trying to stop you. Your arms are the size of my head and probably bigger actually. Thanks for being a freak of nature, Hulk.
Max Unger: There's something comforting in the fact that your center sounds like a robot. You are the anti-Tobeck, good sir, and I mean that in the most loving way possible. Thanks for taking your game to the next level and for persevering through the injuries that held you back early on in your career. This team wouldn't be the same without you.
Bobby Wagner: HOLY SHIT! I mean, I thought you'd be okay and everything but HOLY SHIT! I won't lie, I was disappointed when the Eagles swooped in and selected Mychal Kendricks with the pick before us. Can I take that back? I WAS WRONG. Wags is the real deal and will only continue to progress, in my opinion. Thanks for making me look like an ass clown, Bobby.
Leon Washington: You took the time to give me a shoutout on Twitter. That's pretty genuine and I'm extremely thankful for that. Plus, you've always been one of my favorite players, dating back to your time at Florida State. I always knew you'd have a better career than Reggie Bush. Can't wait for you to take one to the house! It's comin!
Russell Wilson: I could go on and on about #3 but I'll try and keep it as brief as possible. Everything I ever wanted in a quarterback. A leader, calm and collected, severely undersized, big arm, mobile, and you wear Levi's. That makes you a hero in my book sir. Now go out there and hoist some Lombardi's! Thanks in advance, sincerely the 12th Man.
K.J. Wright: What a steal you turned out to be. I'm all about overgrown linebackers, so when I saw that the Seahawks drafted you I had hope that you'd stick to the 53 Man Roster. You did that and much much more. Amazing potential. Thanks for making me forget about the existence of He Who Shall Not Be Named, Caaron Aurry.
Shoutout to all the guys on the Practice Squad as well. You deserve more ink but that will come in time. Keep workin' hard and the 12th Man appreciates the dedication and hard work. As for the 12th Man, I'm especially proud and thankful to be a part of you. What an amazing group of fans made up by an amazing group of people. It's going to feel so good when we finally win the big one, and I think it's going to happen sooner rather than later. There's just too much positive energy emanating from within for it not to. Most of all though, I'd like to thank Pete Carroll and John Schneider. We are so lucky and spoiled to have these two guys in Seattle. Without them and the rest of their amazing staff, NONE of this would be possible. We're 6-4 and competitive in every game, a far cry from years prior. You could even assess that we're hitting our stride at just the right time in the season. This team was built tough, fast, and physical and was built to withstand the marathon of an NFL season. The sky really is the limit with this team. Now enjoy your Thanksgiving and the time with your loved ones (or hated ones if you're with the in-laws, suck it up!) , eat a ton of turkey, and get ready to cheer your balls (or lady parts) off on Sunday! Oh, and I hope you leave some room for the Dolphin that will be served!


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Browse by Medical Category
Thursday, February 16, 2012
Better understanding of cancer-promoting pathway may lead to new strategy for treatment-resistant tumors
Researchers from the Massachusetts General Hospital (MGH) Cancer Center have identified a new potential strategy for treating colon tumors driven by mutations in the KRAS gene, which usually resist both conventional and targeted treatments. In a paper appearing in the Feb. 17 issue of Cell, the team reports that targeting a later step in the pathway leading from KRAS activation to tumor growth may be able to halt the process. "Not all KRAS-mutant colon cancers are the same," says Daniel Haber, MD, PhD, director of the MGH Cancer Center and co-corresponding author of the Cell report. "About half seem to be very dependent on the KRAS mutation for their survival, whereas the other half can continue growing even when KRAS is suppressed. In the KRAS-dependent tumors, we identified how the mutation augments a pathway well known to be involved in colon cancer and identified a key step toward that pathway which, if suppressed, can induce KRAS-dependent tumor cells to undergo apoptosis or programmed cell death." Mutations that activate KRAS expression are common in several types of cancer – most frequently colorectal and lung cancers – and are known to indicate treatment resistance. Drugs that directly target KRAS activity have not been successful, and attempts to identify other potential targets have been challenging, since KRAS mutations may function differently in different cancers. The MGH team first set out to determine the percentage of KRAS-mutant tumors that depend on the presence of the mutation for their growth. Analysis of a large panel of KRAS-mutant tumor cell lines revealed that about half of them die when KRAS-expression is blocked. More detailed analysis of the KRAS-dependent tumors identified several overexpressed genes, and found that blocking expression of a growth-factor-associated enzyme called TAK1 was the most effective way of inducing tumor cell death. The researchers then showed that treatment with a TAK1 inhibitor led to the death of cultured KRAS-dependent colon cancer cells and reduced the size of KRAS-dependent tumors implanted under the skin of mice. Further exploration revealed that KRAS activation contributes to tumor development through a pathway involving both TAK1 and the signaling molecule BMP, which serves to augment the Wnt pathway that is known to be involved in both embryonic development and cancer. "Not all genes that are mutated in cancer can be directly targeted by drugs, but this study shows that if you understand the interrelationships between all the signaling pathways in a particular type of tumor, you may uncover a vulnerability that allows you to bypass the 'undruggable target'," says Haber, who is the Kurt J. Isselbacher/Peter D. Schwartz Professor of Oncology at Harvard Medical School and a Howard Hughes Medical Institute Investigator. "The TAK1 inhibitor we used in this study is not suitable for human administration, but pharmaceutical companies have small-molecule TAK1 inhibitors which have not yet been developed because their potential application was not clear," Haber adds. "Now we need to establish dosage levels where these or related drugs can work against KRAS-dependent colon cancers without being toxic. Those studies, combined with better understanding of the mechanisms underlying this pathway and the consequences of its suppression, will bring us closer to planning for clinical trials." The lead author of the Cell paper is Anurag Singh, PhD, formerly a postdoctoral fellow at the MGH Cancer Center and now at Boston University's Cancer Research Center. Additional co-authors are Michael Sweeney, Min Yu, MD, PhD, Alexa Burger, PhD, Patricia Greninger and Cyril Benes, PhD, all of the MGH Cancer Center; and co-corresponding author Jeffrey Settleman, PhD, formerly of the MGH and now with Genentech, Inc. The study was supported by grants from the National Institutes of Health and the Lustgarten Foundation. Massachusetts General Hospital, founded in 1811, is the original and largest teaching hospital of Harvard Medical School. The MGH conducts the largest hospital-based research program in the United States, with an annual research budget of more than $750 million and major research centers in AIDS, cardiovascular research, cancer, computational and integrative biology, cutaneous biology, human genetics, medical imaging, neurodegenerative disorders, regenerative medicine, reproductive biology, systems biology, transplantation biology and photomedicine.
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Brand Factory - Hyderabad - Dilsukhnagar - Chitra Layout
Calling all Shopaholics!
Brand Factory's Free Shopping Weekend promises everyone the best deals on 200+ brands at unbelievable discounts, spanning brands such as Jack & Jones, Van Heusen, Park Avenue, ONLY, UCB, Vero Moda, Louis Philippe, US Polo and more. The Free Shopping Weekend will make every shoppers' dream of shopping for free, come true.
What you get
Buy merchandise worth INR 5000 (MRP), and pay only INR 2000. What's more, you get this amount back through free apparel worth INR 500, and gift vouchers of INR 1000 & INR 500 through Future Pay Wallet - making your entire shopping experience, effectively, free!
Please note: This offer is valid for a minimum purchase of INR 5000 and multiples thereof.
The two pass options
You need to buy a pass - Premium or Classic - in order to come for the sale. There are limited Premium Passes (INR 249) that admit two, and allow early entry to the store (8 AM - 11 AM) so that you can be the first to get your hands on all the best merchandise! The Classic Pass (INR 99) guarantees entry to the store after 11 AM. And don't worry, the cost for both types of passes will be refunded to you, in the form of Gift Vouchers.
Terms and conditions of Ticketing
Keep customer copy of entry pass with you which is redeemable for next month's shopping
Entry voucher is not refundable in cash or cheque
Management reserve the rights to restrict or withdraw entry at any given point
No duplicate voucher will be issued if lost or misplaced
Free entry for kids below 12 years
Premium passes have limited entry
Pass amount is refundable in the form of gift vouchers
Offer Terms and Conditions
Offer applicable to all merchandise in the store
Any number of merchandise can be clubbed together for the billing of INR 5000
No two offers can be clubbed together
Free Apparel available on select brands only
Correct mobile number is mandatory to avail cash back in future pay
For the free apparel, multiple pieces totaling with INR 500 is allowed
Customer has to pay difference amount if MRP of free merchandise is above INR 500 (for e.g. MRP of free merchandise is INR 799 customer will pay INR 299 (INR 799 - INR 500)
Taxes extra
Future pay cash back will be credited every month starting Jan'18 @ INR 250 per month
Maximum cash back of INR 3000 per bill download future pay app to get cash back
Q) What do I get free?
A) When you shop for Any apparel & footwear worth Rs. 5000 MRP and you pay only Rs. 2000. You get that amount back via an Apparel worth Rs. 500 (from free merchandise zone), 2 Gift vouchers Worth Rs. 500 & Future Pay wallet cashback of Rs. 500.
Q) What if my shopping is worth less than Rs. 5000 MRP?
A) In this case you get a Flat 60% discount on the MRP on ALL apparel and footwear.
Q) What if my shopping is worth more than Rs. 5000 MRP?
A) All multiples of 5000 MRP (10000, 15000, etc.) will be eligible for the offer. For e.g. if your bill value is 10000 MRP, you will get a Flat 60% discount (You pay Rs. 4000) and get 2 Apparel worth Rs. 500 free + 2 GVs worth 500 free & Future Pay wallet cashback of Rs. 500
Q) What if my shopping is worth Rs. 7000 MRP?
A) For e.g. if your bill value is 7000 MRP, you will get a Flat 60% discount and you will elgible for the Freebies of the 5000 MRP slab (get 2 Apparel worth Rs. 500 free + 2 GVs worth 500 free & Future Pay wallet cashback of Rs. 500)
Q) Can I redeem my Payback points for this offer?
A) Yes
Q) Can I pick any Apparel worth Rs. 500 in-store?
A) No, the select brands of Apparel will be placed at free merchandise Zone in the store and must have free merchandise tag. The store team can assist you to pick up your free Apparel before billing.
Q) Can I pick 2 apparel of Rs. 250 from the Free merchandise zone?
A) Yes
Q) Why does customer need to pay Difference amount of Apparel which is more than Rs. 500 MRP?
A) As per management decision, since there are only select merchandise available @ Rs. 500 & under. For e.g. If a customer selects an Apparel of Rs. 800 MRP, he/she will have to pay the difference amount of Rs. 300 at the time of billing. Alternatively, the customer can choose not to pay the difference amount and not opt for the Free Apparel
Q) Can I have some information on the Free GVs?
A) Every bill above Rs. 2000 is eligible for GVs. Each GV value is Rs. 500 (on the purchase of Rs. 1500). These can be redeemed in the months of January and February 2018.
Q) When will Future Pay cashback get credited?
A) For all customers eligible for future Pay cashback, will get credited in their Brand factory Future wallet. For e.g if customer eligible for Rs. 500 cashback, Rs. 250 will be credited on January 15th valid till 31st January 2018 and Rs. 250 on 15th February valid until 28th Feb 2018
Q) Is there a maximum cashback limit per customer?
A) Yes Maximum cashback eligible per user is Rs. 3000. Max cashback per month is Rs. 250 and will be credited every month starting from Jan 2018 depending on the total cashback amount due. For e.g. If a customer is eligible for Rs. 3000 cashback, he will get Rs. 250 cashback per month for 12 months
Q) What if I don't have Future Pay wallet?
A) To avail cashback customer needs to download Future pay wallet app from Play store for android phones and App store for iPhone users. The same will also be communicated to customer via SMS after billing
Q) Ticketing (Rs. 100 & Rs. 250) – online & offline
A) Free shopping Weekend this year will be a ticketed event. Tickets will be in denominations of Rs. 250 (Premium pass x admit 2 people) and Rs. 100 (Classic pass x admit 2 people). These tickets can be bought online at brandfactoryonline.com or on the Paytm App and at any of our stores through a physical ticket.
Q) What does the Rs. 250 Premium pass guarantee?
A) Rs. 250 early bird pass gives the customer the right to entry between 8-11 am before anyone else on any one specific day of the sale
Q) What does the Rs. 100 classic Pass guarantee?
A) Rs. 100 pass gives the customer guaranteed entry from 11 am onwards at any store
Q) Is there a cash refund on the ticket?
A) Tickets once bought cannot be refunded back in cash. Customer will be given fully redeemable Physical GV of the entire value of his ticket which will be valid between 5-31 Dec 2017
Q) How will I get Ticket Refund in Dec through Paytm?
A) If customer has bought Ticket online he will be given a Physical GV at the entry point of the value of his ticket
Q) How will I get Ticket Refund in Dec if I have bought ticket at store?
A) If customer has bought ticket at store he will get a fully redeemable Physical GV of the value of the ticket at store. This Physical GV can be redeemed from 5 to 31 Dec 2017
Brand Factory-Hyderabad-Dilsukh Nagar-Chitra Layout
Brand Factory-Hyderabad-Dilsukh Nagar-Chitra Layout Plot No.1/3 &1/4,CHITRA LAYOUT, SAROOR NAGAR,DILSUKH NAGAR,HYDERABAD-500033,Telangana