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SHAREHOLDER ALERT: Levi & Korsinsky, LLP Notifies Investors of Claims of Breaches of Fiduciary Duty by the Board of Kayak Software Corporation in Connection with the Sale of the Company to priceline.com Incorporated
Jan 04, 2013, 11:58 ET
NEW YORK, Jan. 4, 2013 /PRNewswire/ -- Levi & Korsinsky notifies investors of Kayak Software Corporation ("Kayak" or the "Company") (NasdaqGS: KYAK) of claims of breaches of fiduciary duty and other violations of state law against the board of directors of the Company in connection with the sale of the Company to priceline.com Incorporated (NasdaqGS: PCLN). A complaint was filed in Connecticut state court.
(Logo: http://photos.prnewswire.com/prnh/20120409/MM84375LOGO )
Click here to learn more about the investigation: http://zlk.9nl.com/kayak-software-kyak, or call: 877-363-5972. There is no cost or obligation to you.
Under the terms of the transaction, Kayak shareholders will receive $40 in cash and stock for each share of Kayak stock they own. The transaction has a total approximate value of $1.8 billion. The claims concern whether the Kayak Board of Directors breached their fiduciary duties to stockholders by failing to adequately shop the Company before entering into this transaction and whether priceline.com Incorporated is underpaying for Kayak shares, thus unlawfully harming Kayak stockholders.
If you own common stock in Kayak and wish to obtain additional information, please contact Joseph E. Levi, Esq. either via email at email@example.com or by telephone at (212) 363-7500, toll-free: (877) 363-5972, or visit http://zlk.9nl.com/kayak-software-kyak.
Levi & Korsinsky is a national firm with offices in New York and Washington D.C. The firm has extensive expertise in prosecuting securities litigation involving financial fraud, representing investors throughout the nation in securities and shareholder lawsuits. The attorneys at Levi & Korsinsky have been appointed by numerous courts throughout the country to serve as lead counsel on behalf of shareholders in major securities lawsuits and have successfully recovered multimillion-dollar damages awards on behalf of investors. For more information, please feel free to contact any of the attorneys listed below. Attorney advertising. Prior results do not guarantee similar outcomes.
Levi & Korsinsky, LLP
Joseph Levi, Esq.
Eduard Korsinsky, Esq.
30 Broad Street - 24th Floor
New York, NY 10004
Tel: (212) 363-7500
Toll Free: (877) 363-5972
Fax: (212) 363-7171
SOURCE Levi & Korsinsky, LLP


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NEA News 2005 Volume 23, Number 2
Download this article in pdf format
Nuclear energy and the security of supply
E. Bertel*
Security of energy supply was a major concern for OECD governments in the early 1970s. Since then, successive oil crises, volatility of hydrocarbon prices, as well as terrorist risks and natural disasters, have brought the issue back to the centre stage of policy agendas.
Security of energy supply is clearly part of current government concern. Most often, the issue takes on added importance in OECD countries with energy-intensive economies and/or lacking fossil fuel resources. Despite this, after more than three decades of apparent threats on oil supply and prices, the global dependency of OECD countries on imported oil and gas has not been reduced. In fact, their levels of imports have increased and at the same time the demand from non-member countries, China in particular, has progressed at a high rate. This suggests that so far neither market mechanisms nor government policy measures have tackled the security of supply issue completely. Some of the key questions to be asked in order to do so, as highlighted in the findings of a recent joint IEA/NEA workshop on "Security of energy supply for electricity generation"[1], are:
And, last but not least,
What is security of energy supply?
Defining security of energy supply is not an "academic" concern; it is a prerequisite, from a decision-making viewpoint, for designing adequate policy measures to ensure security of supply and for monitoring their effectiveness. The definition is needed up front to identify the risks raised by insecurity. Furthermore, the choice of the most efficient policy measures aiming at reducing those risks should rely on robust cost/benefit analyses that cannot be achieved without a clear definition of the goal pursued.
The notion of security of energy supply seems clear enough and may be defined in a broad sense as the lack of vulnerability of national economies to volatility in volume and price of imported energy. However, a precise definition of the concept specifying its boundaries is not easy to obtain. Security of energy supply has economic, social and political dimensions at the same time. Energy system analysts and economists can define the economic aspects, but the social and political dimensions are more difficult to capture. In addition, the analysis of energy system evolution shows that national policies aiming at security of energy supply have different objectives depending on the country context and global situation, and therefore follow different approaches.
It is generally agreed that insecurity of supply may result not only from physical disruptions, but also from increases in the prices of imported energy products. Physical disruptions may be caused by insufficient production or transport capabilities resulting from natural causes, socio-political conflicts or by abuse of market power on the part of monopolistic or oligopolistic producers. Similarly, a price increase might result from market mechanisms - demand exceeding supply - or from political decisions.
Can security of supply be measured and monitored?
Generally, to assess the importance of a concern and to measure progress towards addressing it, policy makers rely on indicators. Examples of indicators designed by analysts and commonly used by policy makers in the energy field to evaluate the efficiency of alternative policy measures include gross domestic product (GDP), as well as primary energy consumption per capita and per GDP. Regarding security of energy supply, although some indicators have been proposed by economists or other experts, there is no consensus on a set of relevant indicators and consequently no historical series of data available to assess trends in the field.
A number of energy dependency indicators exist which have been measured, reported and stored in databases together with other energy indicators. For example, it is easy to find time series covering, for each imported energy source, ratios of domestic supply versus total requirements and respective shares of each foreign supplier in total supply. The level of strategic inventories and physical capacities of storage are also relevant indicators which are monitored by some countries and international organisations. But indicators of security of energy supply should represent a degree of risk and the risk associated with dependency varies according to the geopolitical situation of the supplier and importer countries as much as, or even more than, the size of imports.
Another way to quantify the value of security of energy supply is to consider it as an externality and to apply the methods used for valuing other externalities such as environmental impacts. Traditionally, environmental externalities are valued either through damage cost estimates or through the "willingness to pay" for avoiding those damages. Both approaches have proven difficult to apply to security/insecurity of supply and published literature on the subject matter remains scarce.
The complexity of the issue explains why well-established and commonly agreed indicators of security of energy supply do not exist yet. Decision makers, therefore, generally rely on a basket of parameters and qualitative assessments. Ongoing academic studies and empirical analyses of past experience provide some insights into trends in security of energy supply, but more needs to be done to gain a better understanding of the impacts of various policy measures. It is generally agreed that more research is necessary on quantifying benefits of security of supply in order to support policy making.
What role for governments?
When the energy sector of OECD countries was regulated, governments were expected to take energy security into account by carefully planning the energy mix of their country, aiming at a diversified and secure portfolio of supply sources. As the liberalisation of energy markets is implemented progressively in all OECD countries, the role of governments in energy policy making is evolving. In liberalised markets, each supply source competes for shares on purely economic/competitiveness grounds, at least in principle, and decisions are taken by private investors not by governments.
In theory, the market should be sensitive to security risks and react accordingly. In the electricity sector, for example, if oil or gas supplies are interrupted or if prices rise dramatically, there is the possibility that electricity generating profits will suffer. However, the capabilities of liberalised markets to address security of supply concerns are not at all demonstrated. Recent trends, including the rush to gas for electricity generation, tend to demonstrate that markets are not very sensitive to security of supply risks.
Several reasons can explain the relative indifference of markets to security of supply. Maybe the market considers that the costs of reducing the risks of supply interruption would exceed the benefits of enhanced security. Or, perhaps the market relies on the government to alleviate the risks, confident that it will intervene for social and political reasons thereby eliminating economic consequences for private industry. Other reasons are quoted by experts but the point is that if markets fail to respond adequately, governments that wish to ensure security of energy supply for social as well as global macroeconomic reasons must address the issue.
It does not mean that government regulation is always needed. The rationales for intervention have multiplied in recent years - the environment, climate considerations, energy security, protecting vulnerable groups, regional balance, and more. Over-regulating may make the investment climate hostile and be counterproductive. On the other hand, government regulation is a means to internalise external costs and to integrate social concerns in the establishment of market prices. The difficulty is to find the right balance between market mechanisms and regulation to ensure the result at the lowest cost to society.
Measures for ensuring security of supply
Assuming that governments recognise the existence of security of supply risks and decide to address them, many policy measures are available to do so. Moreover, some measures that could address security of supply are also relevant for environmental protection and climate change risk mitigation purposes. The following non-exhaustive list of policy measures provides an overview of the main tools that governments may use to strengthen security of energy supply:
promoting energy efficiency and conservation through norms, standards, information campaigns, subsidies, etc.;
imposing a share of "secure" energy sources in new generation capacity;
introducing taxes on "insecure" energy sources;
subsidizing "secure/domestic" energy sources;
supporting investments in energy storage options through norms or regulation;
implementing tradable permits or certificates for secure energy sources.
Clearly, the list illustrates that the task for governments is to select a relevant policy taking into account uncertainties on indicators and potential adverse impacts of regulation on the effectiveness of energy markets. The adaptation of policy measures to the national context and the evolution of the security of supply risk also raise some issues. For example, political events beyond the control of energy policy makers, such as conflicts in major oil-producing regions of the world, may change drastically the security of oil supply and thereby the value of policy measures taken to alleviate the risks associated with imports from these regions.
As is the case with measures for environmental protection, measures aiming at energy efficiency are win/win options for security of supply as they reduce total demand. Measures to promote domestic sources enhance security of supply, but should be assessed taking into account the relative costs of domestic versus imported sources.
Comparisons between the costs and benefits of enhancing security of supply are essential in support of decision making. Indeed, if the costs are higher than the benefits, society as a whole is losing. The first part of the equation is simple to evaluate in general, but the second is not easy to quantify. Indeed, measuring in strict economic terms the cost of insecurity or the benefit for consumers of secure energy supply at affordable prices is not straightforward. Macroeconomic models and assessments provide some insights into the impact on the national economy of insecurity of energy supply. But ultimately, society's willingness to pay to avoid power cuts and/or gasoline price spikes should be estimated, albeit with some difficulty.
The role of nuclear energy
Nuclear energy offers opportunities for diversifying energy supply and ensuring long-term security. Once technology transfer, if needed, has been achieved, nuclear power plants provide a largely or entirely domestic supply of energy. For this reason, several OECD countries consider nuclear energy as a key policy option for improving security of supply.
The main advantages of nuclear energy in this regard are the limited importance of raw material - natural uranium - in the entire fuel chain producing nuclear electricity, the geopolitical distribution of uranium resources and production capabilities, and the easiness for users to maintain strategic stockpiles of fuel.
Natural uranium is widely available in the world, including in many countries where the geopolitical risk is limited. Its cost represents only a few per cent of the total cost of generating nuclear electricity and therefore uranium price volatility is not a major concern for nuclear power plant owners/operators. Furthermore, maintaining strategic stockpiles representing several years of consumption is physically easy and does not represent a significant financial burden for users.
Reasonably assured uranium resources recoverable at less than 40 USD/kgU represent 25 years of consumption at the present level, while known and total conventional resources recoverable at less than 130 USD/kgU represent respectively 65 and 200 years of consumption. Furthermore, advanced reactors have the potential to reduce significantly the specific consumption of uranium per kWh of electricity generated; fast neutron breeder reactors, for example, can multiply by 50 or so the amount of energy extracted from natural uranium.
In terms of security of supply the geopolitical distribution of uranium resources and production guarantees against risk of disruption. Known uranium resources are found in countries as diverse as Australia , Canada , the United States , Kazakhstan , the Russian Federation , Namibia , Niger and South Africa . Most producing countries, e.g., Kazakhstan , Niger , Namibia , the Russian Federation and the United States , contribute less than 10% to the total. The two major producers, Canada and Australia with 27% and 20% of the total respectively, are OECD countries.
* Total known resources recoverable at less than 130 USD/tU; ** in 2003.
The various other steps of the fuel cycle present different degrees of security of supply. Some fuel cycle services, such as fabrication and transport, are provided by a wide range of suppliers ensuring security and competitive prices. For others, such as enrichment and reprocessing, the number of suppliers is more limited and the competition less effective. However, there has been no example of supply disruption or signs of risk in this field in the past.
In addition to uranium resource availability, safety, physical protection and proliferation regulations may have an impact on the reliability of services delivered by nuclear power plants and the security of nuclear material supply. However, past experience with more than 10 000 reactor-years of operation has shown that such issues have not affected the reliability of nuclear electricity supply.
In countries where a large fleet of standardised reactors is in operation, generic safety problems could require shutting down simultaneously multiple units for refurbishment and upgrade. But such a threat has been a strong incentive for regulators and operators concerned to take efficient preventive measures. Similarly, the evolution of safety regulations could entail in principle extensive unavailability of nuclear power plants needing safety upgrades. However, operators have been able in the past to meet strengthened safety standards without jeopardizing reliability and security of electricity supply.
The international safeguards regime aiming at preventing proliferation of nuclear weapons creates some constraints on nuclear fuel markets associated with declaration, controls and verification of the peaceful uses of nuclear materials. The framework implemented under the auspices of the IAEA does provide, however, a well-defined set of stable rules. Within this framework, complemented by national laws and regulations, nuclear materials for peaceful uses can be traded freely between countries and operators.
Concluding remarks
Energy policy is based on many factors including economic competitiveness, social equity, environmental protection and industrial development goals. From a long-term perspective, the overarching goals of sustainable development will provide the framework for policy making in the energy field, as in other sectors of the economy.
In this context, security and diversity of supply, with their social, environmental and economic dimensions, will remain key drivers in the energy policies of most countries. Better understanding the challenges facing governments and the policy measures available to address them should help in designing and implementing efficient policies. Analysing the role of all energy options, including nuclear energy, is needed to base policy measures on comprehensive, robust assessments.
1. The proceedings of the workshop, held on 24 March 2005 at IEA Headquarters, are available on the IEA and NEA websites.
Related links
Table of contents, NEA News No. 23.2
* Dr. Evelyne Bertel works in the NEA Nuclear Development Division..

subset: commoncrawl


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Thunder at Reign
Faceoff: 7 p.m., Citizens Business Bank Arena (Ontario)
Records: 35-13-5, 75 points; Stockton 27-20-9, 63
Radio: stocktonthunder.com
Skinny: The Thunder's first three-game winning streak since late November will be tested during a busy week. Stockton plays four times in five days, and the logistics aren't easy. It plays today in Ontario, Thursday in Bakersfield, returns to Ontario on Friday and meets the Reign on Sunday at Stockton Arena. ... The Thunder is coming off a weekend of major contributions from two recent arrivals from Oklahoma City of the American Hockey League - goaltender Olivier Roy and defenseman Brandon Davidson. Roy, who played for Stockton last season, won 2-1 in overtime against Ontario on Friday and 4-0 against San Francisco on Saturday. His stats - a 2-0-0 record, 0.49 goals-against average and .984 save percentage - made him a runner-up for ECHL goaltender of the week. Davidson, who recently returned to the ice after a battle with testicular cancer, had both goals in Friday's win and scored three times in his first three games with the franchise. ... Stockton forward Gabriel Levesque is heating up, garnering seven points in the past seven games. ... The Reign has the second-best record in the ECHL's National Conference but has struggled recently and is on a four-game winless streak. ... Ontario's leading active scorer is forward C.J. Stretch, who has 54 points (26 goals, 28 assists) in 53 games.


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Hawks Valley is one of the latest new home communities in west Madison. Located across from Hawks Landing Golf & Swim, residents get to enjoy the peaceful sanctuary of "country life" but still enjoy the amenities of city living. The neighborhood is conveniently located with easy back road access to Epic Systems, Greenway Center, the new expansion to University Research Parks, schools, shops, golf & dining. Hawks Valley Neighborhood, exclusively single family homes include sidewalks & 2-acre park. Bring your OWN BUILDER!
Features Lots and Acreage
|Total Acres: 0.23
|Zoning: Res
|Present Zoning: Single family
|Lot Size:
|Lot Description:
|Taxes: $1,983
|Elementary School: Olson
|Middle School: Toki
|High School: Memorial
|School District: Madison Metropolitan
|Body of Water:
Estimate your monthly mortgage payment
How much can I borrow?
Speak with a mortgage consultant: 608-276-5210


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posted by Thom Holwerda on Mon 22nd Jan 2007 10:40 UTC
Yesterday we reported on 'Ten Reasons Not to Get Vista', featuring two rebuttals. APCMag, the publisher of the first article, now also published a rebuttal. "I've been running Vista at APC since the earliest leaked builds, and witnessed its extraordinary evolution as Microsoft meandered its way towards the final product. Sure, the earlier versions included some bold features which were dropped for the sake of familiarity in the final version, but there's still lots to appreciate about the 'RTM' version of Vista. I'm not talking here about a nicer user interface or security - I figure APC readers already know how to run a secure XP box and how to de-Fisher-Price it. Here are the real benefits: things that will actually make a difference to you day-to-day." Instant Update: The original author has now published a rebuttal to the two rebuttals. Isn't the internet fun?


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Dedicated fans have cried out for a return to his roots for over ten years. This may not be the desired sequel, but it's definitely going to give Spyro's early adventures another opportunity to shine.
spyro 1 and 2 are still fun till this day. feel like playin it right now.
Spyro 2 & 3 are probably the most fun I have had on the PS1. Not really a fan of the first one.
I love the Skelos Badlands level in Spyro 2. The flying powerup never gets old! Even better you can buy all 3 games on the EU PSN for 10 euros, a no brainer really.
Spyro 3 was the first one I played and it amazing, and because of it I went on to play the ratchet and clank series.


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Free Ground Shipping on Orders of $200 or More! Use Coupon Code: GIVETHANKS18
This offer for free shipping and handling applies to ground ship orders over $200 and is valid for orders placed online at www.etundra.com from 11/19/2018 12:00:00 AM thru 11/24/2018 12:00:00 AM UTC. This offer applies to standard ground shipping and handling within the U.S., excluding Hawaii, Alaska and U.S. Territories (other than Washington, D.C.). LTL/freight shipments are not eligible for this offer and may be subject to additional shipping and handling charges. Customers are responsible for all taxes and for all Rush Delivery upgrade fees for 3-Day Express, 2-Day Express and Next Day Delivery. Tundra Restaurant Supply reserves the right to modify or discontinue this offer at any time. Void where prohibited by law. This coupon does not apply to previous purchases, can only be applied to the website(s) listed above, and cannot be combined with other offers. The coupon code will need to be added to the shopping cart or during the checkout process.
Yay, you got a new mixer, but probably found out there are all of these really handy attachments that can improve the efficiency in your kitchen; and you're right, these attachments will have you falling in love with mixing, grating, and grinding all over again! Didn't know you could get a mixer addiction, did you?
Exclusive offers and product updates will be arriving to your inbox soon.


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I LOVE when fellow beauty whores send me their favorite products! That's a big reason for having this beauty blog... sharing!!!
Annah Cuthbert of the U.K. wrote in gushing over the skin and body line LUSH (and a fave conditioner from the local drugstore) and now I share it with you...
Here's what she had to say:
"It is such a fab line, the face packs are just amazing. At first i thought the whole organic, homemade tagline (which at the time was rather original) was just another gimmick but now I'm complete Lush addict.
The brazened honey face pack is a powerhouse of effective ingredients for all tired skins, it apparently exfoliates and detoxifies as well as stimulates and nourishes the skin.
Refreshing herbs and fruit juice are blended with warming Ayurvedic herbs and spices. With almonds to polish and moisturising honey, this blend leaves the skin vibrant and re-visited. You apply to clean skin, leave on for 20 minutes until dry, rinse and voila, glowing goddess.
Another great face pack by LUSH is the BB Seaweed, which has a lovely relaxing and reviving fragrant. It is a mineral rich mask to cleanse, soften and beautify all skin types. This blend contains fresh, nutritious seaweed and seaweed absolute. Cleansing kaolin, antiseptic honey, calming aloe vera and rose absolute make this a great mask for everyone. there are also masks for wrinkles, problem skin, you name it, it caters for all.
The dream cream is also really delish, it is an incredibly soothing body lotion for troubled skin. it is Lush`s best-selling product because it makes sore skin feel good again. It calms irritations, reduces redness and banishes blotches. It contains just about everything nature makes for soothing your skin.
I can use every product in LUSH with ease as I trust nature over science when it comes to skincare, and even though I have very sensitive cells, I have not received a single irritation from the line.
Another product I highly recommend which has transformed my thirsty head of highlights, is this leave in conditioner called, Vitapointe. I found it in my local drugstore, right at the bottom, behind some mainstream products. There were only two bottles left, which intrigued me. i asked the sales assistant and she told me it is a really popular product, but got discontinued ages ago, and due to all the latest array of options Vitapointe gets ignored. but the older generations snap it up like flies, and i always think the oldies knew their stuff when it came to beauty ( quality always). the product contains masses of different minerals, vitamins and ingredients such as beeswax, to feed your hair, no muss no fuss. you apply a tiny pearl sized drop onto dry hair and it makes such a huge difference after using it for a month my hair actually appears glossy and manageable which is rare for a highlight addict. the best bit is its so cheap it cost 2 pounds which i think is like $3 or $4. this should def be a beauty classic."
To view the entire LUSH line, click HERE!
Tuesday, March 11, 2008
Fellow Beauty Whore Recommendation...
I LOVE when fellow beauty whores send me their favorite products! That's a big reason for having this beauty blog... sharing!!!
Labels: fellow beauty whore recommendation, lushStumble This!
2 comments:
- Anonymous said...
I gotta tell ya, I've been using Boscia for nearly two weeks now and love it as well. My skin has honestly never looked better.
- Court said...
I'm intrigued by that conditioner--will have to look for it. Thanks for the recommmendation! :-)


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As CNN's Candy Crowley writes today, it's never too early for the political world to play veepstakes. So, join the game — but don't bet on Nikki Haley.
In an ABC "Nightline" interview set to air tomorrow at 11:35 p.m. ET, the South Carolina governor said she would turn down the vice presidential nomination if the eventual GOP nominee were to offer it to her. Her strong statement against the VP nod might help to diffuse some of the suspicion aroused by her early endorsement of Mitt Romney. Perhaps she didn't endorse him merely to position herself well in the Republican Party. Maybe she really did — and does — think he'd be the best person for the job of president. That's certainly the tone she struck in the "Nightline" interview:
A Tea Party favorite endorsed by Sarah Palin during her gubernatorial race in 2010, Haley's endorsement in the Republican primary was a highly coveted one. The South Carolina governor came out early for Mitt Romney, criss-crossing the state with him in the weeks before the state's January primary.
Despite her stalwart campaigning on his behalf, Haley claims she has no interest in being his running mate. If offered the vice presidential slot, Haley said she would not take it.
"I'd say, 'Thank you, but no,'" she said. "I made a promise to the people of this state. And I think that promise matters. And I intend to keep it."
But the governor fell short of delivering a South Carolina win to Romney. Instead the GOP presidential candidate suffered a substantial defeat in the Palmetto state, falling 13 percentage points behind Newt Gingrich.
Haley brushed off Romney's loss.
"South Carolinians are strong, independently-minded people," Haley said. "At the end of the day, they make their own decisions. And I respect them for that. And I welcome that. And I told him that from the very beginning."
Interestingly, Haley sounded more open to the possibility of a 2016 presidential run. She said it's not something she can imagine right now — but it's also not something she would rule out. "Life has surprised me constantly," she explained.
But would the GOP be open to her? Haley's seemingly premature endorsement of Romney was interpreted by some Tea Partiers as an almost-heretical enrollment in "the establishment," but she remains an inspiring figure in the Republican Party nevertheless. A low approval rating in South Carolina notwithstanding, she boasts at least one significant gubernatorial success. Under her administration, employers have created 22,000 new jobs in South Carolina. She's also still a conservative female politician in the Sarah Palin mold — tough, thick-skinned, still feminine. It's hard to think the governorship of South Carolina is the last important office she'll hold.


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Details Behind The Jake/Reese Split
Reese Witherspoon and Jake Gyllenhaal officially pulled the plug on their three-year relationship over a series of phone calls earlier this month.
Why over the phone? Jake has been in Pittsburgh the past three months shooting his new movie, Love And Other Drugs. Reese has been busy filming How Do You Know? in Los Angeles.
"It broke his heart," an insider reveals to Us Weekly. "[They] fought constantly in the past few months [but] no one cheated. There was no drama."
"She felt pressured to wed again but she wasn't ready," another insider adds. "She couldn't give Jake enough and she got cold feet. Jake wanted all of her. She really worried that they didn't have enough in common… He was great with the kids (Ava and Deacon), but she felt like he didn't get the whole scope of what that entailed."


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A new biopsy test can identify men at high risk of recurring prostate cancer with almost 80% accuracy, say scientists.
The test singles out patients likely to relapse after surgery or radiotherapy by looking for specific genetic changes at 100 sites in DNA.
Researchers believe the "genetic signature" test will help doctors determine which patients need extra help after initial treatment.
"Men who fail treatment within two years may be at the highest risk of dying from their prostate cancer," said lead scientist Professor Robert Bristow, from the University of Toronto, Canada.
"Existing methods for identifying high risk patients are imperfect, so new tests are required that are better at predicting which patients will have their cancer recur.
"These men can then be offered additional treatments, such as chemo and hormone therapy, that will combat the prostate cancer throughout their entire body, rather than therapies solely focused on the prostate, in order to improve their chances of survival.
"This is the first report of a test using information derived from biopsy samples that can predict with close to 80% accuracy which men are at high or low risk of their prostate cancer recurring."
Story continues below the slideshow:
The scientists analysed biopsy tissue samples taken from 126 treated men with prostate cancer who were thought to be at intermediate risk of their cancer returning.
They looked at each patient's whole genetic code, or genome, searching for missing, extra, or irregular sections of DNA.
From this information they were able to identify signature patterns linked to a high or low risk of recurring cancer.
The test was used to predict outcomes for a second group of 150 patients who had their prostate tumours removed by surgery.
See Also:
Popular Vitamin And Mineral Supplements 'Can Dramatically Increase Risk Of Prostate Cancer'
A secondary study by the same team found that tumours affected by hypoxia - starved of oxygen -were most associated with worse survival.
"Importantly, we found that when we combined the signature with the additional information about the tumour's oxygen content, this made the genetic test even more accurate," said Prof Bristow, who presented the results at ESTRO33, the 33rd meeting of the European Society for Radiotherapy and Oncology in Vienna, Austria.
Men with low levels of genetic changes and low hypoxia had the best outcomes, with 93% lasting five years without their cancer recurring.
Only 49% of men with high levels of genetic alterations and high hypoxia escaped a cancer recurrence for five years.
Prof Bristow said: "These results will enable us to develop a new way of personalising medicine, so that we can improve cure rates and reduce the chances of the cancer spreading to other parts of the body".
Dr Iain Frame, director of research at the charity Prostate Cancer UK, said: "Being able to distinguish aggressive cancers from those which are less so is one of many unanswered questions in prostate cancer research.
"A test which could do this would be hugely important for the 40,000 men diagnosed with the disease every year. For this reason Prostate Cancer UK has made this area a key part of its research strategy.
"This new research is interesting because it suggests that looking at the DNA from individual tumours as well as the surrounding environment could tell us early on whether a cancer is going to develop in to one of the more harmful forms.
"It's too early to tell for sure whether this method could help differentiate the tigers from the pussy cats but if further research shows that it can then it could help to ensure men are offered the best possible treatment options for their individual situation and ultimately improve outcomes."


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Agriculture, Food, and the Environment
Kathleen A. Brosnan and Jacob Blackwell
Throughout history, food needs bonded humans to nature. The transition to agriculture constituted slow, but revolutionary ecological transformations. After 1500
The American Antinuclear Movement
Paul Rubinson
Spanning countries across the globe, the antinuclear movement was the combined effort of millions of people to challenge the superpowers' reliance on nuclear weapons during the Cold War. Encompassing an array of tactics, from radical dissent to public protest to opposition within the government, this movement succeeded in constraining the arms race and helping to make the use of nuclear weapons politically unacceptable. Antinuclear activists were critical to the establishment of arms control treaties, although they failed to achieve the abolition of nuclear weapons, as anticommunists, national security officials, and proponents of nuclear deterrence within the United States and Soviet Union actively opposed the movement. Opposition to nuclear weapons evolved in tandem with the Cold War and the arms race, leading to a rapid decline in antinuclear activism after the Cold War ended.
American Environmental Diplomacy
Kurk Dorsey
From its inception as a nation in 1789, the United States has engaged in an environmental diplomacy that has included attempts to gain control of resources, as well as formal diplomatic efforts to regulate the use of resources shared with other nations and peoples. American environmental diplomacy has sought to gain control of natural resources, to conserve those resources for the future, and to protect environmental amenities from destruction. As an acquirer of natural resources, the United States has focused on arable land as well as on ocean fisheries, although around 1900, the focus on ocean fisheries turned into a desire to conserve marine resources from unregulated harvesting.
The main 20th-century U.S. goal was to extend beyond its borders its Progressive-era desire to utilize resources efficiently, meaning the greatest good for the greatest number for the longest time. For most of the 20th century, the United States was the leader in promoting global environmental protection through the best science, especially emphasizing wildlife. Near the end of the century, U.S. government science policy was increasingly out of step with global environmental thinking, and the United States often found itself on the outside. Most notably, the attempts to address climate change moved ahead with almost every country in the world except the United States.
While a few monographs focus squarely on environmental diplomacy, it is safe to say that historians have not come close to tapping the potential of the intersection of the environmental and diplomatic history of the United States.
American Environmental Policy since 1964
Richard N. L. Andrews
Between 1964 and 2017, the United States adopted the concept of environmental policy as a new focus for a broad range of previously disparate policy issues affecting human interactions with the natural environment. These policies ranged from environmental health, pollution, and toxic exposure to management of ecosystems, resources, and use of the public lands, environmental aspects of urbanization, agricultural practices, and energy use, and negotiation of international agreements to address global environmental problems. In doing so, it nationalized many responsibilities that had previously been considered primarily state or local matters. It changed the United States' approach to federalism by authorizing new powers for the federal government to set national minimum environmental standards and regulatory frameworks with the states mandated to participate in their implementation and compliance. Finally, it explicitly formalized administrative procedures for federal environmental decision-making with stricter requirements for scientific and economic justification rather than merely administrative discretion. In addition, it greatly increased public access to information and opportunities for input, as well as for judicial review, thus allowing citizen advocates for environmental protection and appreciative uses equal legitimacy with commodity producers to voice their preferences for use of public environmental resources.
These policies initially reflected widespread public demand and broad bipartisan support. Over several decades, however, they became flashpoints, first, between business interests and environmental advocacy groups and, subsequently, between increasingly ideological and partisan agendas concerning the role of the federal government. Beginning in the 1980s, the long-standing Progressive ideal of the "public interest" was increasingly supplanted by a narrative of "government overreach," and the 1990s witnessed campaigns to delegitimize the underlying evidence justifying environmental policies by labeling it "junk science" or a "hoax."
From the 1980s forward, the stated priorities of environmental policy vacillated repeatedly between presidential administrations and Congresses supporting continuation and expansion of environmental protection and preservation policies versus those seeking to weaken or even reverse protections in favor of private-property rights and more damaging uses of resources. Yet despite these apparent shifts, the basic environmental laws and policies enacted during the 1970s remained largely in place: political gridlock, in effect, maintained the status quo, with the addition of a very few innovations such as "cap and trade" policies. One reason was that environmental policies retained considerable latent public support: in electoral campaigns, they were often overshadowed by economic and other issues, but they still aroused widespread support in their defense when threatened. Another reason was that decisions by the courts also continued to reaffirm many existing policies and to reject attempts to dismantle them.
With the election of Donald Trump in 2016, along with conservative majorities in both houses of Congress, US environmental policy came under the most hostile and wide-ranging attack since its origins. More than almost any other issue, the incoming president targeted environmental policy for rhetorical attacks and budget cuts, and sought to eradicate the executive policies of his predecessor, weaken or rescind protective regulations, and undermine the regulatory and even the scientific capacity of the federal environmental agencies. In the early 21st century, it is as yet unclear how much of his agenda will actually be accomplished, or whether, as in past attempts, much of it will ultimately be blocked by Congress, the courts, public backlash, and business and state government interests seeking stable policy expectations rather than disruptive deregulation.
Cesar Chavez and the United Farm Workers Movement
Matt Garcia
In September 1962, the National Farm Workers Association (NFWA) held its first convention in Fresno, California, initiating a multiracial movement that would result in the creation of United Farm Workers (UFW) and the first contracts for farm workers in the state of California. Led by Cesar Chavez, the union contributed a number of innovations to the art of social protest, including the most successful consumer boycott in the history of the United States. Chavez welcomed contributions from numerous ethnic and racial groups, men and women, young and old. For a time, the UFW was the realization of Martin Luther King Jr.'s beloved community—people from different backgrounds coming together to create a socially just world. During the 1970s, Chavez struggled to maintain the momentum created by the boycott as the state of California became more involved in adjudicating labor disputes under the California Agricultural Labor Relations Act (ALRA). Although Chavez and the UFW ultimately failed to establish a permanent, national union, their successes and strategies continue to influence movements for farm worker justice today.
DDT and Pesticides
Frederick Rowe Davis
The history of DDT and pesticides in America is overshadowed by four broad myths. The first myth suggests that DDT was the first insecticide deployed widely by American farmers. The second indicates that DDT was the most toxic pesticide to wildlife and humans alike. The third myth assumes that Rachel Carson's Silent Spring (1962) was an exposé of the problems of DDT rather than a broad indictment of American dependency on chemical insecticides. The fourth and final myth reassures Americans that the ban on DDT late in 1972 resolved the pesticide paradox in America. Over the course of the 20th century, agricultural chemists have developed insecticides from plants with phytotoxic properties ("botanical" insecticides) and a range of chemicals including heavy metals such as lead and arsenic, chlorinated hydrocarbons like DDT, and organophosphates like parathion. All of the synthetic insecticides carried profound unintended consequences for landscapes and wildlife alike. More recently, chemists have returned to nature and developed chemical analogs of the botanical insecticides, first with the synthetic pyrethroids and now with the neonicotinoids. Despite recent introduction, neonics have become widely used in agriculture and there are suspicions that these chemicals contribute to declines in bees and grassland birds.
Energy in American History
Aaron Sachs
Energy systems have played a significant role in U.S. history; some scholars claim that they have determined a number of other developments. From the colonial period to the present, Americans have shifted from depending largely on wood and their own bodies, as well as the labor of draft animals; to harnessing water power; to building steam engines; to extracting fossil fuels—first coal and then oil; to distributing electrical power through a grid. Each shift has been accompanied by a number of other striking changes, especially in the modern period associated with fossil fuels. By the late 19th century, in part thanks to new energy systems, Americans were embracing industrialization, urbanization, consumerism, and, in a common contemporary phrase, "the annihilation of space and time." Today, in the era of climate change, the focus tends to be on the production or supply side of energy systems, but a historical perspective reminds us to consider the consumption or demand side as well. Just as important as the striking of oil in Beaumont, Texas, in 1901, was the development of new assumptions about how much energy people needed to sustain their lives and how much work they could be expected to do. Clearly, Americans are still grappling with the question of whether their society's heavy investment in coal- and petroleum-based energy systems has been worthwhile.
Environmental and Conservation Movements in Metropolitan America
Robert R. Gioielli
By the late 19th century, American cities like Chicago and New York were marvels of the industrializing world. The shock urbanization of the previous quarter century, however, brought on a host of environmental problems. Skies were acrid with coal smoke, and streams ran fetid with raw sewage. Disease outbreaks were as common as parks and green space was rare. In response to these hazards, particular groups of urban residents responded to them with a series of activist movements to reform public and private policies and practices, from the 1890s until the end of the 20th century. Those environmental burdens were never felt equally, with the working class, poor, immigrants, and minorities bearing an overwhelming share of the city's toxic load. By the 1930s, many of the Progressive era reform efforts were finally bearing fruit. Air pollution was regulated, access to clean water improved, and even America's smallest cities built robust networks of urban parks. But despite this invigoration of the public sphere, after World War II, for many the solution to the challenges of a dense modern city was a private choice: suburbanization. Rather than continue to work to reform and reimagine the city, they chose to leave it, retreating to the verdant (and pollution free) greenfields at the city's edge. These moves, encouraged and subsidized by local and federal policies, provided healthier environments for the mostly white, middle-class suburbanites, but created a new set of environmental problems for the poor, working-class, and minority residents they left behind. Drained of resources and capital, cities struggled to maintain aging infrastructure and regulate remaining industry and then exacerbated problems with destructive urban renewal and highway construction projects. These remaining urban residents responded with a dynamic series of activist movements that emerged out of the social and community activism of the 1960s and presaged the contemporary environmental justice movement.
The Environment in the Atomic Age
Rachel Rothschild
The development of nuclear technology had a profound influence on the global environment following the Second World War, with ramifications for scientific research, the modern environmental movement, and conceptualizations of pollution more broadly. Government sponsorship of studies on nuclear fallout and waste dramatically reconfigured the field of ecology, leading to the widespread adoption of the ecosystem concept and new understandings of food webs as well as biogeochemical cycles. These scientific endeavors of the atomic age came to play a key role in the formation of environmental research to address a variety of pollution problems in industrialized countries. Concern about invisible radiation served as a foundation for new ways of thinking about chemical risks for activists like Rachel Carson and Barry Commoner as well as many scientists, government officials, and the broader public. Their reservations were not unwarranted, as nuclear weapons and waste resulted in radioactive contamination of the environment around nuclear-testing sites and especially fuel-production facilities. Scholars date the start of the "Anthropocene" period, during which human activity began to have substantial effects on the environment, variously from the beginning of human farming roughly 8,000 years ago to the emergence of industrialism in the 19th century. But all agree that the advent of nuclear weapons and power has dramatically changed the potential for environmental alterations. Our ongoing attempts to harness the benefits of the atomic age while lessening its negative impacts will need to confront the substantial environmental and public-health issues that have plagued nuclear technology since its inception.
Epidemics in Indian Country
David S. Jones
Few developments in human history match the demographic consequences of the arrival of Europeans in the Americas. Between 1500 and 1900 the human populations of the Americas were traBnsformed. Countless American Indians died as Europeans established themselves, and imported Africans as slaves, in the Americas. Much of the mortality came from epidemics that swept through Indian country. The historical record is full of dramatic stories of smallpox, measles, influenza, and acute contagious diseases striking American Indian communities, causing untold suffering and facilitating European conquest. Some scholars have gone so far as to invoke the irresistible power of natural selection to explain what happened. They argue that the long isolation of Native Americans from other human populations left them uniquely susceptible to the Eurasian pathogens that accompanied European explorers and settlers; nothing could have been done to prevent the inevitable decimation of American Indians. The reality, however, is more complex. Scientists have not found convincing evidence that American Indians had a genetic susceptibility to infectious diseases. Meanwhile, it is clear that the conditions of life before and after colonization could have left Indians vulnerable to a host of diseases. Many American populations had been struggling to subsist, with declining populations, before Europeans arrived; the chaos, warfare, and demoralization that accompanied colonization made things worse. Seen from this perspective, the devastating mortality was not the result of the forces of evolution and natural selection but rather stemmed from social, economic, and political forces at work during encounter and colonization. Getting the story correct is essential. American Indians in the United States, and indigenous populations worldwide, still suffer dire health inequalities. Although smallpox is gone and many of the old infections are well controlled, new diseases have risen to prominence, especially heart disease, diabetes, cancer, substance abuse, and mental illness. The stories we tell about the history of epidemics in Indian country influence the policies we pursue to alleviate them today.
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Leveling Inscription from 1 - 375
Leveling Inscription from 1 - 375
With the new expansion WoTLK coming, many new features have been added since patch 3.0.2. The new profession Inscription is one of them.
Inscription is different from any profession to date while utilizes a lot of traits for other professions. The biggest difference between Inscription versus any other profession is at skill level 50+, you can start making "end game" items and glyphs (end game in the sense that level 70-80 players will want to use the items you've created). Glyphs are unique in that typically no Glyph is "better" then another Glyph - each have their benefits depending on the situation. So whether your making a skill level 75 Glyph or a skill level 375 Glyph both could equally desirable.
Image of the new Glyph Window
How it Works: The Three Part Process
Inscription is a three part process: Herbs -> Pigment -> Ink -> Glyphs. To create pigments you will have to use the new "Milling" ability to turn stacks of 5 herbs into 2-3 pigments. The type of herb directly affects the type of pigments it creates (see table below). From there you can use pigments to create inks - some inks require a combination of pigments and lower level inks to create. Finally Glyphs generally require a mix of certain inks, parchments (new purchasable item), and herbs to create.
Types of Ink and How to Obtain Them
● Ivory Ink = 1 Alabaster Pigment. (Peacebloom, Silverleaf, Earthroot)
● Moonglow = 2 Alabaster Pigment. (Peacebloom, Silverleaf, Earthroot)
● Midnight = 2 Dusky Pigment. (Mageroyal, Briarthorn, Swiftthistle, Bruiseweed, Stranglekelp)
● Hunter's = 1 Verdant Pigment. Uncommon (Mageroyal, Briarthorn, Swiftthistle, Bruiseweed, Stranglekelp)
● Lion's = 2 Golden Pigment. (Wild Steelbloom, Grave Moss, Kingsblood, Liferoot)
● Dawnstar = 1 Burnt Pigment. Uncommon (Wild Steelbloom, Grave Moss, Kingsblood, Liferoot)
● Jadefire = 2 Emerald Pigment. (Fadeleaf, Goldthorn, Khadgar's Whisker, Wintersbite)
● Royal = 1 Indigo Pigment. Uncommon (Fadeleaf, Goldthorn, Khadgar's Whisker, Wintersbite)
● Celestial = 2 Violet Pigment. (Firebloom, Purple Lotus, Arthas' Tears, Sungrass, Blindweed, Ghost Mushroom, Gromsblood)
● Fiery = 1 Ruby Pigment. Uncommon (Firebloom, Purple Lotus, Arthas' Tears, Sungrass, Blindweed, Ghost Mushroom, Gromsblood)
● Shimmering = 2 Silvery Pigment. (Golden Sansam, Dreamfoil, Mountain Silversage, Plaguebloom, Icecap)
● Ink of the Sky = 1 Sapphire Pigment. Uncommon (Golden Sansam, Dreamfoil, Mountain Silversage, Plaguebloom, Icecap)
● Ethereal = 2 Nether Pigment. (Found from herbs native to Outland)
● Darkflame = 1 Ebon Pigment. Uncommon (Found from herbs native to Outland)
What to Save for Power Leveling Inscription
If you follow the list below you will need the following to level 1-375:
Any combination of stacks of 5 of the "OR" herbs listed below will work. Example: 60x Liferoot, 100x Kingsblood, 60x Wild Steelboom and 20x Grave Moss would be a total of 240 herbs from that block.
● 140x Peacebloom OR Silverleaf OR Earthroot
● 80x Mageroyal OR Briarthorn OR Swiftthistle OR Bruiseweed OR Stranglekelp
● 240x Wild Steelbloom OR Grave Moss OR Kingsblood OR Liferoot
● 280x Fadeleaf OR Goldthorn OR Khadgar's Whisker OR Wintersbite
● 220(260 to be safe)x Firebloom OR Purple Lotus OR Arthas' Tears OR Sungrass OR Blindweed OR Ghost Mushroom OR Gromsblood
● 220x Golden Sansam OR Dreamfoil OR Mountain Silversage OR Plaguebloom OR Icecap
● 400x Any native Outland herbs
Inscription Trainers
There is an inscription 1-300 trainer in each of the 4 major cities in Azeroth (just ask a guard for the location) - to train from 300-375 you will need to head over to Hellfire Peninsula in Outland.
Elise Brightletter in Ironforge
Catarina Stanford in Stormwind City
Feyden Darkin in Darnassus
Thoth in The Exodar
Michael Schwan in Honor Hold (Master Trainer)
Jo'mah in Orgrimmar
Margaux Parchley in Undercity
Poshken Hardbinder in Thunder Bluff
Zantasia in Silvermoon City
Neferatti in Thrallmar (Master Trainer)
Leveling Inscription
Notes on the Guide
Scroll of XXXX = Scroll of Agility/Intellect/Spirit/Stamina/Strength
Glyph of XXXX = The glyphs that are currently Orange(or JUST turned yellow) and require only 1 Ink when possible. (100% skill up) They normally come in 2's or but occasionally come with just 1 glyph later on. You can do that one glyph or use some other glyph if you want. Any glyph will give 5 more 100% skill ups after it turns yellow, and the next 5 after that will be about 60% the time it will skill up.
1 to 20
Ivory Ink (1 Alabaster Pigment) x20
20 to ~38
Scroll of XXXX (1 Ivory Ink, 1 Light Parchment) x20
~38 to ~58
Moonglow Ink (2 Alabaster Pigment) x22
~58 to 75
Bleached Vellum (1 Moonglow Ink, 1 Light Parchment ) x~17
75 to 80
Midnight Ink (2 Dusky Pigment) x20
80 to 81
Minor Inscription Research (1 Moonglow Ink, 2 Light Parchment) x1 (and every 20 hours after that for quite a while)
81 to 100 - double check every glyph that requires 1 Midnight Ink, they change it up.
Glyph of XXXX (1 Midnight Ink, 1 Light Parchment) x20
100 to 105
Lion's Ink (2 Golden Pigment) x65
105 to 125
Glyph of XXXX (1 Lion's Ink, 1 Common Parchment) x26
125 to ~131
Dawnstar Ink (1 Burnt Pigment) x[All you found] (I had 14)
~131 to ~138
Strange Tarot (2 Dawnstar Ink, 1 Lion's Ink, 1 Common Parchment) x[All you can] (I had mats for 7)
~138 to 150
Glyph of XXXX (2 Lion's Ink, 1 Common Parchment) x13
150 to 155
Jadefire Ink (2 Emerald Pigment) x70
155 to 175
Glyph of XXXX (1 Jadefire Ink, 1 Common Parchment) x20
175 to 180
Royal Ink (1 Indigo Pigment) x[All you have] I had 15
180 to ~187
Arcane Tarot (2 Royal Ink, 1 Jadefire Ink, 1 Common Parchment) x[All you can] (I had mats for 7)
~187 to 200
Glyph of XXXX (2 Jadefire Ink, 1 Common Parchment) x20
200 to 205
Celestial Ink (1 Violet Pigment) x55
205 to 225
Glyph of XXXX (1 Celestial Ink, 1 Heavy Parchment) x20
225 to 235
Scroll of Agility IV (1 Celestial Ink, 2 Heavy Parchment) x11
235 to 240
Glyph of XXXX (2 Celestial Ink, 1 Heavy Parchment) x5
240 to 250 - Will probably be normalized to 2 Inks by live, but we'll see.
Glyph of Cleaving (1 Celestial Ink, 1 Heavy Parchment) x10
250 to 255
Shimmering Ink (2 Silvery Pigment) x55
255 to 260
Scroll of Spirit V (1 Shimmering Ink, 1 Heavy Parchment) x5
260 to 275
Glyph of XXXX (1 Shimmering Ink) x15
275 to 290
Ink of the Sky (1 Sapphire Pigment) x15
290 to 300 This seems crazy, but the Ink of the Sky levels make up for these last 10.
Glyph of XXXX (1 Shimmering Ink, 1 Heavy Parchment) x~35
300 to 305
Ethereal Ink (2 Nether Pigment) x65
305 to 310
Glyph of XXXX (1 Ethereal Ink, 1 Heavy Parchment) x5
310 to 329
Glyph of XXXX (1 Ethereal Ink, 1 Resilient Parchment) x20
329 to 345
Glyph of XXXX (2 Ethereal Ink, 1 Resilient Parchment) x16
345 to 355 (Glyph of Whirlwind)
Glyph of XXXX (1 Ethereal Ink, 1 Resilient Parchment) x5
355 to 365
Glyph of XXXX (2 Ethereal Ink, 1 Resilient Parchment) x30
And you are done! Note that there is a new ink at 350 as well as Glyphs that uses the new ink - but they all require Northrend materials so I skipped it for this guide. 360-365 is BRUTAL as everything is green at this point. At 365 EVERYTHING turns gray - it is not possible to hit 375 at the moment.
Note that I did not write this guide, I just edited it. I did the Text Formatting, removed some things, added some things like images, etcetra.
Please note that all links are courtesy of WoWhead!
Please, leave a comment if:
You have any additional information that I should add to this guide.
You have any suggestions about the Text Formatting.
You want to leave a comment about how it worked out.
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Patch 3.3.3 changes
Submitted by Lycander on Thu, 2010-03-25 01:25.
Heya, Shikamaru. As of patch 3.3.3, several of the glyphs have had their inks dropped form 2 to 1. You'd have to go through them all to check which ones exactly. Just thought I'd mention it.
Herb locations
Submitted by Blazeron on Mon, 2009-08-03 18:58.
Hey, Shikamaru,
I really like this guide, it really helped me. So just as a suggestion maybe you could add in which area(s) you can farm the herbs the best.
The guide is really good and keep on making such great guides
Just got here, will stay long...
Submitted by Becvar on Mon, 2009-04-13 09:50.
From 290-300 Scroll of Stamina VI is only 1 Shimmering Ink and 2 Heavy Parchment each, and is orange till 300. MUCH more efficient than making 35 or so glyphs for the same skillups.
Couple of things
Submitted by tovya on Sun, 2009-03-08 22:09.
Hey Shikamaru,
Great guide, I'm glad you found it for us to follow and edited it ^^ Couple of things I've noticed:
1. Celestial Ink requires x2 Violet Pigment not x1 (possibly changed in a patch after you pasted this here)
2. In comparing guides from the web (and because I just love this site and hate having to leave off of it) I noticed there are a few other guides out there that have more steps. Reason: (example) 120-125 Glyph of XXX 125-135 Glyph of XXX instead of going straight 120-135. Possibly might want to change it up if you get some free time on your hands?
So like A) 120-125 Glyph of XXX B) Train new Glyph's C) Glyph of XXX 125-135... I've noticed that doing this, changing up the glyph you skill from as soon as new ones are available even if every 5 levels will help save on loads of materials.
Just some thoughts ^.^ Otherwise, is perfect! I'm at 205 skill now, if I notice any other changes like the Celestial Inks, I'll post back!
Alliance - Gnomeregan
Tovya - 71 NE Rogue
Tovyard - 65 Dwarf Hunter
Aledris - 64 Draenei DK
Alliance - Gnomeregan
Tovya - 71 NE Rogue
Tovyard - 65 Dwarf Hunter
Aledris - 64 Draenei DK
Following your guide
Submitted by Adrobiel on Thu, 2009-03-05 04:09.
Following your guide currently to level my inscription. All good so far, except i have noticed near the start:
20 to ~38
Scroll of XXXX (1 Ivory Ink, 1 Common Parchment) x20
Those particular scrolls use Light Parchment.
Thanks fixed
Submitted by Jahwo on Sat, 2009-03-07 12:24.
Thanks fixed
I'm pretty sure Bleached
Submitted by Alarius on Sat, 2009-02-28 08:08.
I'm pretty sure Bleached Vellum doesn't exist in the game at the moment. All that is orange to me at 58 are Scroll of Recall and Armor Vellum. Scroll of Recall is probably the better choice since it only requires one parchment and one ink.
Might Want to Give Credit to the Original Writers?
Submitted by duckbyday on Wed, 2008-11-12 05:11.
http://www.wtbblue.com/profession-guides/204-inscription-1-375 funny since they have a leveling guide as well...
Glad you cleared that up
Submitted by Jame on Mon, 2008-11-17 22:28.
Glad you cleared that up
I'm sure shikmaru will make
Submitted by Jame on Wed, 2008-11-12 12:29.
I'm sure shikamaru will make the necessary modifications as soon as possible. Thanks for pointing this out.
Where you have the notes on
Submitted by Pharoahty on Thu, 2008-10-30 15:34.
Where you have the notes on the guide part you have one small typo.
"Leveling Inscription
Notes on the Guide
Scroll of XXXX = Scroll of Agility/Intellect/Spirit/Stamina/Strenght"
I couldn't think of a signature =(
can i say..
Submitted by mystk on Sat, 2009-02-21 23:32.
I noticed in the opening paragraph:
no Glyph is "better" then another (then should be than)
both could equally desirable. (could *be)
-- This guide is wonderful, so easy on the eyes to read and gave me great info
Im all ready to go farming for herbs now to get my inscription lvl up
Thanks for providing it, this page is going to be my reference from now on ^_^
Awesome, can't think of
Submitted by Jame on Thu, 2008-10-23 18:48.
Awesome, can't think of anything else right now
Looks great Here's my first
Submitted by Jame on Wed, 2008-10-22 19:41.
Looks great Here are my suggestions:
1. Add wowhead links for each item. I know it's a lot of work, but it makes the guide so much better. I've done it for the Ivory Ink to show you how it looks
2. For headlines and titles, I recommend not using underline and italics. Keep it simple like this:
Types of Ink and How to Obtain Them
It's just easier for the eyes to read, and it just looks neater overall
Size=15 / 16 / 17 / 18 is fine. More is too much.
Oh, it's really easy. It's
Submitted by Jame on Wed, 2008-10-22 20:21.
Oh, it's really easy. It's like a normal link, besides you use the wowhead url.
First write the name of the item (it doesn't even have to be the accurate name), like for example:
Arcanite Reaper
Then go to wowhead and search for Arcanite Reaper, copy the url. In this case, the url is http://www.wowhead.com/?item=12784
If you're using the text formatting toolbar, simply select the text, click on the "Add Code to format text as link" button, a window will pop up, paste the wowhead url in there.
Lots of suffering saved
Submitted by Trogdor on Sat, 2008-12-27 21:14.
at 290 now you can mill outland herbs and make them into the ethereal ink. This might not make a difference for those who are using this guide after leveling up an herbing toon from level 1 but on my dk I farmed up all the other levels of herb and this one I was doing in hellfire for the dreamfoil etc, and making ethereal inks for the last 10 levels to 300 seems easier then having to stockpile all those simmering inks for 10 levels.


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Jamie Williamson and Dustin Fisher, Pratt, announce the birth of their daughter, Amethyst Jean, at 12:53 p.m. Nov. 12, 2013, at Pratt Regional Medical Center. She weighed 7 pounds, 10 ounces and was 19 1/2 inches long.
Stephanie, 13, David, 11, and Grandon, 2, welcome their sister.
Grandparents are Becky and Bryon Cartwright, Don and Beverly Fisher and Vickie Fisher.
Great-grandparents are Eleanor Taylor, Wilma Fisher and Virgie Critzer.


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Greek1319. didaskalia -- instruction (the function or the information)
... didaskalos Definition instruction (the function or the information) NASB Word Usage
doctrine (9), doctrines (3), instruction (1), teaching (7), teachings (1). ...
//strongsnumbers.com/greek2/1319.htm - 7k
1322. didache -- doctrine, teaching
3544. nomikos -- relating to law, learned in the law
1129. gumnasia -- exercise
Strong's Hebrew8451. torah -- direction, instruction, law
... instruction, law NASB Word Usage custom (1), instruction (10), instructions (1),
Law (1), law (188), laws (10), ruling (1), teaching (7), teachings (1). ...
/hebrew/8451.htm - 6k
False Teachings of the Apostasy.
The Teachings of the Greek Poets and Philosophers Confirmatory of ...
The Character of Its Teachings Evidences the Divine Authorship of ...
The Rewards for Following Jesus' Teachings
Psalm 119 Part 9 Desire of Knowledge; Or, the Teachings of the ...
From Examples Tertullian Passes to Direct Dogmatic Teachings He ...
I Will Address the Master in one of his Own Phrases. Why, after ...
Psalm 119:09. Ninth Part. Desire of Knowledge; Or, the Teachings ...
The Bramble and the Agnos the Symbol of Chastity; the Four Gospels ...
A Short Repetition of all the Highest Teachings Written by the ...
ThesaurusTeachings (34 Occurrences)
... Multi-Version Concordance Teachings (34 Occurrences). ... (WEY). Matthew 15:9 but in
vain do they worship me, teaching as teachings commandments of men. ...
/t/teachings.htm - 15k
Tradition (13 Occurrences)
Commands (216 Occurrences)
Uncleanness (56 Occurrences)
Resemble (15 Occurrences)
Builds (18 Occurrences)
Education (4 Occurrences)
Election (6 Occurrences)
Bible ConcordanceTeachings (34 Occurrences)
Matthew 7:24 "Every one who hears these my teachings and acts upon them will be found to resemble a wise man who builds his house upon rock;
Matthew 7:26 And every one who hears these my teachings and does not act upon them will be found to resemble a fool who builds his house upon sand.
Matthew 15:9 but in vain do they worship me, teaching as teachings commandments of men.
Mark 7:7 But in vain do they worship me, teaching as their teachings commandments of men.
Mark 8:38 Every one, however, who has been ashamed of me and of my teachings in this faithless and sinful age, of him the Son of Man also will be ashamed when He comes in His Father's glory with the holy angels."
Luke 9:26 For whoever shall have been ashamed of me and my teachings, of him the Son of Man will be ashamed when He comes in His own and the Father's glory and in that of the holy angels.
John 6:68 "Master," replied Simon Peter, "to whom shall we go? Your teachings tell us of the Life of the Ages.
John 12:47 And if any one hears my teachings and regards them not, I do not judge him; for I did not come to judge the world, but to save the world.
John 12:48 He who sets me at naught and does not receive my teachings is not left without a judge: the Message which I have spoken will judge him on the last day.
1 Corinthians 11:2 Now I am pleased to see that you keep me in memory in all things, and that you give attention to the teaching which was handed down from me to you.
Galatians 5:20 Worship of images, use of strange powers, hates, fighting, desire for what another has, angry feelings, attempts to get the better of others, divisions, false teachings,
Colossians 2:22 referring to things which are all intended to be used up and perish--in obedience to mere human injunctions and teachings?
2 Thessalonians 2:15 So then, brethren, stand your ground, and hold fast to the teachings which you have received from us, whether by word of mouth or by letter.
1 Timothy 4:1 Now the Spirit expressly declares that in later times some will fall away from the faith, giving heed to deceiving spirits and the teachings of demons;
Hebrews 6:1 Therefore leaving the teaching of the first principles of Christ, let us press on to perfection-not laying again a foundation of repentance from dead works, of faith toward God,
Hebrews 13:9 Don't be carried away by various and strange teachings, for it is good that the heart be established by grace, not by food, through which those who were so occupied were not benefited.
2 Peter 2:1 But there were false prophets among the people, as there will be false teachers among you, who will secretly put forward wrong teachings for your destruction, even turning away from the Lord who gave himself for them; whose destruction will come quickly, and they themselves will be the cause of it.
Revelation 22:9 But he said to me, "Oh, do not do that. I am a fellow bondservant of yours, and a fellow bondservant of your brethren the Prophets and of those who are mindful of the teachings of this book. Worship God."
Psalms 119:19 I am living in a strange land: do not let your teachings be kept secret from me.
Psalms 119:35 Make me go in the way of your teachings; for they are my delight.
Psalms 119:47 And so that I may take delight in your teachings, to which I have given my love.
Psalms 119:66 Give me knowledge and good sense; for I have put my faith in your teachings.
Psalms 119:86 All your teachings are certain; they go after me with evil design; give me your help.
Psalms 119:115 Go far from me, you evil-doers; so that I may keep the teachings of my God.
Psalms 119:127 For this reason I have greater love far your teachings than for gold, even for shining gold.
Psalms 119:131 My mouth was open wide, waiting with great desire for your teachings.
Psalms 119:143 Pain and trouble have overcome me: but your teachings are my delight.
Psalms 119:151 You are near, O Lord; and all your teachings are true.
Psalms 119:166 Lord, my hope has been in your salvation; and I have kept your teachings.
Psalms 119:172 Let my tongue make songs in praise of your word; for all your teachings are righteousness.
Psalms 119:176 I have gone out of the way like a wandering sheep; make search for your servant; for I keep your teachings ever in mind.
Psalms 132:12 If your children keep my word, and the teachings which I will give them, their children will be rulers of your kingdom for ever.
Proverbs 7:2 Keep my commandments and live, and my teaching as the apple of thine eye.
Daniel 9:10 neither have we obeyed the voice of Yahweh our God, to walk in his laws, which he set before us by his servants the prophets.
Related Terms
Strengthened (113 Occurrences)
LinksBible Concordance • Bible Dictionary • Bible Encyclopedia • Topical Bible • Bible Thesuarus


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The original city of Palma dates back to Roman times, and modern day residents of the old quarter are still digging up artifacts in their gardens. Balanced on a seawall above the marina is the amazing gothic Cathedral, icon of the city, with some of the world's largest stained glass windows. Also high on the artistic scale is the Museum of Contemporary Spanish Art featuring works by masters including Picasso, Miró, Gris, and Dali. Mother Nature's aesthetic achievements can be found in the Caves of Drach – mystical caverns where the play of shadow and light on the rock formations stimulates the imagination.
Featured Voyages
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This massive gothic structure from the 13th century is known locally as La Seo. The beautiful stained glass windows are well worth the visit, and include the world's largest rose window.
Palacio Almudaina
Palacio Almudaina
Located opposite of the cathedral and on the site of an old Roman citadel, this former Arabic fortress was once used as a residence for Moorish kings. It's still used by the Spanish royal family for civil functions.
Drach Caves
Drach Caves
Travel to Porto Cristo, one of the oldest anchorages of the island, to the famous Caves del Drach. This series of mysterious caverns is a natural phenomenon that provides a play of shadow and light. Admire the largest underground lake in the world, Lake Martel, before learning about the Balearic Islands pearling history at a local pearl factory.About Shore Excursions +Book Now +
Featured Palma De Mallorca, Spain
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Obama - January 20th, 2009
By TotalPhoto.ca
by Leon Switzer + John MacDonald
This is the price your customers see. Edit list price
About the Book
This book covers the entire Inauguration day of President Barack Obama. We covered the entire distance of The Mall photographing all the events of the day. At 12 noon, we photographed many people from the steps of The Lincoln Memorial during the swearing in and speech of the new President of The United States, Barack Obama. We did not get to see President Obama, but, we have well over 200 photos of things you might not have seen or experienced. This is a large format book and notes a lot of the key monuments in Washington DC, and captures one of the great days in American history and is printed on premium paper. To see all of the photos in the book, please go to www.TotalPhoto.ca. Thank-you
Features & Details
- Category History
Large Format Landscape, 13×11 in, 33×28 cm
102 Pages
- Publish Date Feb 04, 2009
- Tags the mall, leon switzer, 20th 2009, potn, flickr, color, colour, pembroke, petawawa, travel, switzer, january, inauguration, barack, change, DC, nikon, canon, history, art, pictures, cnn, moment, biden, newspaper, flag, canada, ontario, ottawa, totalphoto, photography, capital, washington, 44th, president, obama
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About the Creator
Leon Switzer
Ontario, Canada
Owner of TotalPhoto.ca, a company started just a few short years ago, we can quote just about any job and cover it with speed and professionalizm. Please take the time and have a look.


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Couple Trying To Trademark Bitcoin Via Dubious Claims
from the any-penalties-for-such-filings? dept
Mouchon? Oh wait. Michel Mouchon is the person the original offer was made to... I'm sure that's just a coincidence, right?
Yeah, it's not hard to put two and two together here. I mean, just the fact that they're claiming the first use in commerce was June 22nd of this year should lead to the application not passing the laugh test. But I do wonder, are there penalties for trying to mislead the USPTO in a trademark filing?


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SJ.- The American Psychiatric Association formally recognizes ADHD as the clinical term for all attention deficit or hyperactivity issues. Adults who have trouble concentrating at work, feel they can never get fully organized or remember to keep appointments actually may be experiencing ADHD.
Thanks in part to widespread media coverage of Attention Deficit Disorder and Attention Deficit Hyperactivity Disorde among children, many inaccurately assume these conditions are exclusive to children. However, there are adults who experience similar symptoms. ADD and ADHD are often misunderstood and misdiagnosed. Characteristics of both conditions can be carried over into adulthood. ADD is the colloquial name given to the ADHD condition when hyperactivity or impulsive behaviors are not present. However, the American Psychiatric Association formally recognizes ADHD as the clinical term for all attention deficit or hyperactivity issues. Adults who have trouble concentrating at work, feel they can never get fully organized or remember to keep appointments actually may be experiencing ADHD. Many adults carry over ADHD tendencies from childhood. If the disorder was not diagnosed during childhood, an adult may not know he or she has it. The National Institute of Mental Health offers that roughly 4 percent of the adult U.S. population has ADHD. Of those people, around 40 percent have severe symptoms.
Just like children, adults can be assessed by a mental health professional to see if ADHD may be the culprit behind some of their problems. This person will use a ratings system to see if the person meets the diagnostic criteria for ADHD. Questions about childhood behaviors may be asked and a psychological test may be conducted. It can be important for an adult to receive a confirmation of ADHD, because only then can he or she begin treatment. This may include medications or behavioral therapy to alleviate symptoms. Left untreated, ADHD can have a profound impact on quality of life.
Many adults with the disorder find it is difficult to pay bills or manage money, leading to financial problems. Others may miss appointments or have trouble performing on the job. Behavioral issues may be frowned on by supervisors and seen as bucking the system. Adolescents and adult students may experience many of the same hurdles as younger children in school. The inability to concentrate or behave in a classroom setting can compromise learning ability and advancement. Adults with ADHD may find the disorder has negative effects on a marriage or other relationship. Getting a firm diagnosis can help the patient and the other person work on a system that helps them function and promote the relationship.
Symptoms of ADHD. Adults can experience impulsivity and hyperactivity and be easily distracted. Impulsivity in adults may include behaviors such as gambling or drinking, promiscuity or engaging in verbal outbursts. Hyperactivity is showcased through restlessness and fidgeting. A person may not be able to stay still for long or possibly have a nervous tick. With distractibility, adults may not be able to focus on one task, jumping from thing to thing and leaving projects unfinished. Boredom may come frequently. Recognizing the symptoms of adult ADHD can mean faster diagnosis and treatment options that can restore quality of life. CL


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Jane Goodall, now a world-renowned primatologist, blurred the lines between human and ape with her research. She discovered that chimps make tools, wage war, are omnivores and sometimes adopt unrelated youngsters. Behaviors and traits that were previously thought to be unique to humans were found in the tribes of chimps that Goodall observed during her years at what is today Tanzania's Gombe National Park.
On Sept. 28, Goodall will bring her life's work to La Jolla for a dinner to benefit the Jane Goodall Institute (JGI), a global nonprofit that empowers people to make a difference for all living things. Goodall will discuss the work of JGI, which continues her pioneering research and efforts to protect chimpanzees and their habitats. The institute, which celebrates its 35th ann-iversary this year, is widely recognized for establishing innovative community-centered conservation and development programs in Africa, as well as Jane Goodall's Roots & Shoots, a global environmental and humanitarian youth program.
Goodall, at 78, is still very much active in her work, both as a primatologist and as a conservationist. She travels at least 300 days a year, visiting every corner of the earth to raise awareness about the state of chimpanzees and the current threats to the planet. Though Goodall, who calls Gombe her favorite place on earth, would love to spend more time at the national park, she feels her time is better spent empowering youth to be better environmental stewards, said Mary Humphrey, CEO of JGI. Goodall still manages to return to Gombe twice a year, Humphrey said, to "observe the ongoing field work, visit with old friends — chimp and human — and recharge her batteries."
The work at Gombe, meanwhile, continues on without too many changes from Goodall's first efforts there starting in 1960.
"In some ways, the work is very much the same," Humphrey said. "Field staff, the majority of whom are Tanzanian, go into the forest each day and track select chimps and record their behavior."
What's different, however, is how technology has aided research. When Goodall first ventured into the jungle, she had little more than binoculars and a notepad. Today, the field staff uses geographic information system (GIS) technology and high-resolution satellite imagery to track chimpanzee populations and the impact human settlements are having on their environment. Data collected are scanned and sent digitally to the Jane Goodall Institute Center for Primate Studies at Duke University, where the information is entered into an archive of more than 50 years of data to be used by scientists from around the world. Additionally, Humphrey said, "The institute is working with Google Earth Outreach on a pilot climate-change effort that is enabling local communities to take a leadership role in protecting the restored forests surrounding Gombe and the larger nearby ecosystems where additional chimpanzee populations live."
Using Google technologies, Hum-phrey explained, forest monitors collect the data to prove their efforts are protecting the forest, "An essential requirement if the area is to participate in the global program for Reducing Emissions from Deforestation and Degradation (REDD) — which will qualify the communities for financial support for sustainable development plans," she said.
Since beginning her studies, Goodall's efforts have shifted from primatology to conservation — efforts that were particularly stepped up when high human birth rates and periodic influxes of people fleeing wars in Burundi and the Democratic Republic of the Congo led to high population density around the park. Deforestation and loss of chimp habitats became painfully clear when, in 1992, Goodall flew over Gombe and witnessed the almost total loss of trees.
"She realized the problems faced by the villagers, such as poverty, lack of clean water, education and primary healthcare, and overused farmland were intrinsically related to the environmental issues," Humphrey said. "She saw that there were more people living around the park than the land could support."
Today, Goodall works to keep the institute's various efforts afloat — a daunting challenge, given the significant resources needed to carry on the research and operations — while trying to impart her message of conservation to future generations.
At the Sept. 28 event, held at the home of Bill and Michelle Lerach in La Jolla Farms, guests will be treated to refreshments by Snake Oil Cocktail Co. and an intimate poolside dinner with Goodall.
The event will include a live auction with unique items like a trip to see the sandhill crane migration with Goodall; a VIP safari tour at the San Diego Zoo Safari Park with a private dinner prepared by celebrity chef Brian Malarkey; a framed tool used by a chimpanzee, featuring Goodall's signature; and more.
For more information about the benefit dinner and to purchase tickets, visit www.dinnerwithjane.com. For more information about Goodall and the JGI, visit www.janegoodall.org.


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Message Board
Flora Fraser Message Board
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Author Fraser's Book Reviews
Princesses: The Six Daughters of George III
Princesses: the six daughters of George III Flora Fraser John Murray, 2005 ISBN: 0719561094 King George III and Queen Charlotte of England (1760�1820) had 15 children, of which six were daughters. The King was devoted to them, but could not bear to let them go. Two of his sisters had married abroad, been ill-treated by their husbands and led very unhappy lives; the Royal Marriages Act of 1772 forbade princes and princesses to marry without the co...


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Author Robinson's Book Reviews
LEGEND Bantam, Mar 2001, 5.99 ISBN: 0553579649 In 1476 England, Galen de Marlowe hides in remote Durance Guarde so he can concentrate on the visions of a malevolent being threatening the royal family. He sees a shadow smothering two boys who Galen assumes are the sons of his friend Edward the King. Honor Stafford heads home after four mostly lonely years of marriage to Aymer Jennings, who recently died in an accident. She decides to t...
Never Trust a Lady
Bantam, Aug 2003, 6.50, 320 pp. ISBN: 0553584235 In 1861 Lady Eva Sparrow flees the boredom of aristocratic Victorian England to explore the United States. Her plan is to travel from New York to Texas and back before returning to her homeland. Though she heard of slavery and felt appalled that someone could treat another human as property, Eva becomes outraged to see the plight of blacks when she reaches Natchez, Mississippi, but has no idea ho...


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Show Events
The most striking, highly visible feature of the stadium is 133 metre tall arch that sits above the north stand. The steel arch is 315 metres long and will become the longest single roof structure in the world and will be visible right across London.
The arch supports all of the weight of the north roof and 60 per cent of the weight of the southern side. By using an arch to bear some of the weight of the southern roof it is possible to retract the south roof to allow light an air onto the pitch.
The arch also ensures that there are no pillars in the new stadium which could obstruct the views of fans.
One of the key challenges of the design team was to keep the famously high standard of the Wembley pitch while, at the same time, designing a stadium with stands that are higher and closer to the pitch than the original stadium and give better uninterrupted views.
Many new stadia have suffered from poor pitches as the stands in them stadia can leave large sections of the pitch in almost permanent shadow and grass demands direct sunlight to grow effectively.
For this reason, the sliding roof remains an integral part of the design for the new Wembley.
Instead, computer models have been made of air movement and sunlight on the existing pitch and the unique moving roof designed for the new Stadium.
One of the most recognised features of Wembley is the presentation of trophies from the Royal Box rather than on the pitch. The new Royal Box is in the traditional position - in the middle of the north stand - as in the old Wembley Stadium.
A key feature of the current stadium is that almost all spectators sit in a single bowl rather than four separate stands. This is a central feature of the new design with almost all supporters or concert-goers able to share the event with 90,000 other fans creating a more memorable atmosphere.
The acoustics of the new ground will take the original stadium as a benchmark. Recordings taken during the 1999 FA Cup Final and models of the Stadium created by using three blasts of white noise during the England v Poland game in 2000 will form the basis of sophisticated computer models that will allow the design team to finely tune the acoustics of the new stadium.
The orientation of the Stadium remains east west, with the main façade pointing north down Olympic Way. To accommodate an external concourse all around the Stadium, the new building will move 30 metres north, towards Wembley Park Station. This new stadium concourse will make it much easier, and safer, to enter and leave the stadium.
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