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How to Make Olive Oil Hair Gel at Home
Say hello to your new favorite hair gel.
Did you know that you can create your own gel infusions right at home? Okay, you may not have everything your favorite hair care brands have inside their labs, but you just might have the essentials to create a one-time product. Consider D.I.Y. hair products your go-to when you are all out of your favorite hair care or styling products, or when you just want to try the next best thing going viral on your Instagram, Pinterest, and Facebook feed.
Today we're talking about olive oil hair gel, the organic hair gel that many of our favorite YouTubers are ranting and raving about when it comes to defining their curls (and adding moisture while doing so), as well as styling their edges, smoothing them into place.
D.I.Y. Olive Oil Hair Gel: Here's How to Make Your Own
Don't you want to get in on all the goodness olive oil hair gel that seems to be delivered? Well, you can, and we've got everything you need to know in order to make your own right at home. Read on:
Why Use Olive Oil Hair Gel?
For many, many years, women have been using olive oil hair gel in their skin and hair care routines. Olive oil is lightweight and easily penetrates into skin and hair. No wonder curly-haired gals are obsessing over this key ingredient!
What kind of olive oil should you use?
Now here's the great debate: There are different versions of olive oils out there and it can be quite confusing to decide which form of the oil is best to use. We suggest going with extra virgin olive oil (EVOO). Why? Extra virgin olive oil contains antioxidants with vitamin E, which is beneficial to your hair. This form of oil is more expensive but worth every penny if you're looking for something that will benefit and add to the healthy look and feel of your hair.
How to make olive oil hair gel
Making the gel isn't rocket science, but there is definitely more than one way to create a concoction. An easy way to create this gel is to add 1-2 teaspoons of warm olive oil to your fave gel. Refrigerate after creating your mixture if needed.
Another way to create your homemade olive oil hair gel is to infuse your flaxseed gel into it during the process. While your flaxseed gel is boiling, add a few drops of olive oil into your pot and stir to mix well.
What kind of hairstyles can you create with olive oil hair gel?
Just about any style that calls for a gel is ideal for your D.I.Y. gel. The point of using this gel on your hair is to have a product that delivers moisture and doesn't dry your hair out. Use your gel to create wash-and-go styles, tame your edges, create sleek updos, and more.
Do you want to give more olive oil-infused hair care products a try? Our EIC has a lot to say about the Suave Professionals Avocado + Olive Oil Smoothing Shampoo and Conditioner. We also love the Suave Professionals Avocado + Olive Oil Smoothing Leave-In Conditioner. Read more about her experience with this line.
Have Color Commitment Issues? Colored Hair Gel May Be Your Answer
Give your hair a splash of color with wash-out-color hair gel.See article
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Andis Master Cordless Clipper #12470 & Cordless T-Outliner Li Trimmer #74000 & Cordless Titanium Foil Shaver TS-2 #17255
1-Andis Professional Cordless Master Clipper #12470
The classic performance you expect from the Master®, now with cordless freedom and convenience! Lithium-ion battery delivers over 90 minutes of nonstop run time; charges in just 1 hour. Extremely powerful, the high-speed rotary motor with blade speeds over 7,200 SPM, featuring constant speed technology; won't drag or stall. Unbreakable, lightweight aluminum housing for years of dependable use. The carbon-steel blade is adjustable from fine to coarse (#000–#1). Cord/cordless operation features an LED light to indicate battery power levels.
- Lithium-ion battery delivers over 90 minutes of nonstop run time.
- its also has a Extremely powerful, high-speed rotary motor.
- Unbreakable lightweight aluminum housing.
- Cord/Cordless operation features an LED light to indicate battery power levels
- Includes premium charging stand
2-Andis Cordless T-Outliner Li Trimmer #74000
- Charger Stand
- Tube of Blade Oil
- 4 Attachment Combs (1/16″, 1/8″, 1/4″, 3/8″)
3-Andis Profoil Lithium Plus Foil Shaver TS-2 #17255
- Best for finishing fades and removing stubble
- Lithium-ion battery provides maximum power with a charging stand
- Delivers up to 80 minutes of run time on a single charge – 2x longer than other shavers
- Lightweight – less than 5 ounces. Powerful and quiet rotary moto
- Equipped with gold titanium hypo-allergenic foils for irritation-free shaving
perfect for finishing fades and removing stubble for an ultra-close smooth shave. The staggered hypo-allergenic foil heads provide the perfect cut while the lithium-ion battery provides 80 minutes of nonstop run time on a single charge. Cord/cordless operation also guarantees that you never have to stop shaving even if your charge gets low. It has a powerful and quiet rotary motor and weighs less than 5 ounces. Gold titanium hypo-allergenic foil provides irritation-free shaving.

subset: commoncrawl


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Follow in the footsteps of Benjamin Franklin, George Washington and many other outstanding citizens. Volunteering at Bailey's Crossroads Volunteer Fire Department can be very rewarding. Regardless if you volunteer to be a firefighter, emergency medical technician, board member or quartermaster, knowing that you made a difference in people's lives when they need it the most is one of the best feelings you can ever have.
Our volunteers serve in two distinctive roles:
• Operational Volunteers provide immediate assistance at the scene of an emergency. The training http://www.fcvfra.org/recruit/training/ requirements for becoming a fully operational volunteer could be substantial. Great amounts of time and effort go into making an operational volunteer. Operational volunteers can serve in the following capacities:
• Administrative members work behind the scenes to make it all happen. Roles include, but not limited include: Board member, Quartermaster (Logistics), Fund-Raising, Public Education etc.
Membership Applicants must meet certain strict requirements to be considered eligible for membership. Active volunteers are also expected to fulfill several participation, certification, and compliance requirements to remain involved. To be considered eligible for membership, you must:
• Be a U.S. citizen or current legal resident with at least 24 months of U.S. residency (documentation may be required)
• Successfully pass a background investigation
• We recommend that you plan to live locally for at least 3 years, given the considerable time involved in training to become a competent volunteer.
• We also require attendance at regular departmental meetings and participation in administrative functions (e.g., fundraising).
• The minimum age is 18 Our Volunteers are community minded individuals just like you. Join us today. You'll learn a lot, help others and receive some nice benefits. http://www.fcvfra.org/recruit/benefits/
To apply or get more information about joining our station click here, Once on the form, please select Bailey's Crossroads VFD for the department and a member of our station will be in contact with you.
BXVFD is a not-for-profit 501(c)3 organization serving the citizens of Bailey's Crossroads and Fairfax County since 1942
Site Content © 2020


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Doctor of Pharmacy and Masters in Public Health
As the US and global populations increase and as diseases and therapies evolve, the need for leadership in health and wellness and healthcare institutions has grown. It is imperative that healthcare professionals seek to enhance community welfare and resolve complex health issues through advanced education, research, and service if we are to improve the well-being of communities in the United States and abroad. The University of Tennessee Health Science Center College of Pharmacy and The University of Memphis School of Public Health have established a dual degree program that allows students to jointly earn the Doctor of Pharmacy degree and a Masters of Public Health (MPH).
Masters in Public Health:
- Courses offered by the University of Memphis School of Public Health
- Core courses are available online
- Option to concentrate in one of 5 core areas (some core areas with face-to-face coursework)
- 42 credit program (8 credits can be applied to the elective requirement of the Doctor of Pharmacy degree, and 15 credits from UTHSC COP can apply to the 18 elective credits for the MPH)
- Requirements:
- Completion of 1 year of the Doctor of Pharmacy Program
- GPA 3.0 or higher
Contact information:
Vikki Nolan, DSc, MPH, at email@example.com (University of Memphis)


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When filing your yearly income tax returns, it is important to ensure that you provide details of all your income, deductions and investments. If the Income Tax Department finds any mismatch of information or mistakes in your tax return, it will send you a notice u/s 139(9).
If your return is found defective, then I-T department will send you a defective return notice under section 139(9) of the Income Tax Act. You will get 15 days of time from the date of receiving the notice to rectify the defect in your return.
The detailed process to submit the Response to defective notice is as below:
Step 1: Go to Income tax portal and Login to the same
Step 2: Now click on "e-File" tab and select the option "e-File in response to notice under section 139(9)".
Step 3: On successful validation if there is any defective notice raised by either CPC/AO, the below screen will be displayed, select submit for the concerned defective return for which you are going to submit a response.
Step 4: For defective notice raised by CPC, the below screen will be displayed:
Step 6: Now if you agree with the effect then just fill your Income Tax Return by rectifying the defect by selecting Return u/s 139(9) and mention date of original return, acknowledgement number, Notice number and Notice date. Once you do that then generate its xml file and upload it in the above screen. After that you'll see the below screen:


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Honey Garlic Pot Roast
There are some things that never get old. No matter how often they happen, you never get tired of them. You're always happy to see them coming, sad to see them gone, and waiting for the next time that they happen again.
Weekends. Football season. Christmas. Reruns of The Golden Girls. Cheap Honey Crisp Apples (the result of which was a wonderful Apple Cider Cinnamon Bread). I can never get enough of any of it.
Another thing that never gets old:
Pot Roast.
Pot roast is one of those things that just about everyone can relate to in some way. We've all had it. We all love it. It's everything we love about home, comfort food, and good memories. It's wonderful on Sundays. It's wonderful during the week after a long day after work. It's wonderful hot. It's wonderful cold. See where I'm going with this? It's just everything wonderful.
I haven't made a pot roast in a really long time. Why? I don't know. It's one of those unexplainable questions of the universe that we're just not supposed to make sense of, I guess. All I knew going to the grocery store this week was that I was buying a chuck roast, and I was making a pot roast out of it. I have some recipes for some 'unique' pot roasts that I have yet to test out, but this time around I wanted to stay pretty traditional with my approach. Nothing fancy. No fireworks. Sometimes it's the simplest things that have the best results.
My grandma was subscribed to this mailing database called Great American Recipes where she would receive several recipe cards in the mail for a while. Since she doesn't like to do as much cooking as she used to, she would just give the cards to me. As a result, I've got quite a collection of recipe cards from GAR now- they even sent a cute little binder to put it in.
This recipe was in one of the mailing packs that they sent. It seemed like a pretty straightforward pot roast recipe, and I liked the idea of rubbing honey over the meat before searing it off. So I tried it. Well, the smell alone was enough for me to decide that this was a good life choice. And the taste was enough to make me want to slap myself silly for letting such a long time pass since I've last made pot roast.
Long story short, this pot roast rocks. Don't be an idiot like me and take a prolonged hiatus from pot roast roast…ing. Do the right thing. Make this.
By the way, if you don't love pot roast, then I just don't know what you're doing with your life.
FEED(ME) BACK: What's one dish you like to cook that never gets old?
Honey Garlic Pot Roast
Recipe courtesy of Great American Recipes
Yield: 6 servings
*2 tbsp vegetable oil
*2 1/2 lb boneless beef chuck roast
*2 tbsp honey
*4 cloves garlic, minced
*3 cups beef broth
*1lb. baby red potatoes, (1-1 1/2 inches in diameter) scrubbed
*1 cup of baby carrots
*2 envelopes (1 1/4 oz each) beef gravy mix
*1 can (14.5 oz) diced tomatoes with roasted garlic, drained
1. Heat the oil in a Dutch oven over medium heat. Rub the roast with the honey. Firmly press the garlic onto the roast. Cook the roast until browned on both sides, about 10 minutes.
2. Pour the broth over the roast. Bring to a boil. Reduce heat to low and simmer for 1 hour. Turn the roast over and add the potatoes and carrots. Cover roast and simmer until the roast and vegetables are tender, 45-55 minutes longer.
3. Transfer the roast and vegetables to a large deep platter, using a slotted spoon. Discard all but 2 1/2 cups liquid from the pot. Whisk in the gravy mix and increase heat. Stir in tomatoes. Bring to a boil and cook for 2 minutes.
4. Pour half of the sauce over the roast and vegetables to serve. Pass the remaining sauce with the sauce.


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Acts 10, Acts 11:1-18.
Chapter 9
A Soldier's Desire; or, Prayer and its answer.
This is rather a long story, perhaps some of my hearers may say tonight, but it is a very interesting one. If it has no interest to you, my friend, it has a very deep interest for me; and for this reason, that the Spirit of God describes to us, in this remarkable narrative, the way in which the gospel of the grace of God first went out to the Gentiles. You must bear in mind that the Jew was nationally in relationship with God, but the Gentile — the heathen, for that is the meaning of the word — had no link with God. It is to such that the apostle Paul says, "Wherefore, remember, that ye being in time past Gentiles in the flesh, who are called Uncircumcision, by that which is called the Circumcision in the flesh made by hands; that at that time ye were without Christ, being aliens from the commonwealth of Israel, and strangers from the covenants of promise, having no hope, and without God in the world" (Eph. 2:11-12). As Gentiles, they had no link with God, and therefore you will not understand this chapter unless you see clearly, that God was beginning a new work of grace. It was an entirely new departure in the ways of God. He was sending out, and was determined to send out, beyond the limits of Israel, the gospel — the good news of His love. He was going to proclaim that glad tiding to nations who had never heard it before.
I do not know what you feel, but I can say, from the bottom of my heart, Thank God, that He has done so; because, I happen to be one of them, and, I suppose, you are too. If you are a Jew, there is a Saviour for you, but here is the first time that the news is proclaimed, that there is a Saviour, and an eternal salvation for the Gentiles, and we are introduced here to the first company of Gentiles who, as such, heard and received the gospel.
The first trophy of grace among the Gentiles was this remarkable centurion, Cornelius by name. Evidently he was an Italian, for he belonged to the Italian band. He was a Roman centurion, and a man of remarkable character, but then living in Palestine, at Caesarea, which was a most important military post, viewed from the standpoint of the Romans. He was there in charge of a company of soldiers. Somehow or other this man had a great longing to know God's salvation. He was a man seeking light, and no person can read this scripture without being impressed that this man was in downright, dead earnest; absolutely, red-hot earnest, as I might say. His character was quite unique for a Roman soldier, for he was "a devout man, and one that feared God, with all his house, which gave much alms to the people, and prayed to God alway" (ver. 2).
Now what about the man that never prays? God can save even that man, but it is interesting to see that this man was prayerful. He was not only prayerful, but it comes out that he was fasting until the ninth hour of the day. The man was, as I said, in downright earnest: he had not broken his fast until three o'clock in the afternoon. What was he about? He had spent his time in looking to God for light. No wonder that man got blessing: he was in such deep, downright earnestness, I repeat, before God. He wanted blessing, and he got it. Do you want blessing? For any sake, be in earnest then!
I see here the value of prayer. It is not that I would tell you, that you must pray in order to be saved: that would be to make salvation depend upon prayer, which it does not. But I find when a man is really awakened by the Spirit of God, and is exercised before God about his soul, that the longings of his heart will come out in prayer. He has not got much light; but he can pray. He wants Christ: he knows there is something to be had, which he does not possess. The centurion was a man, I have no doubt, who at this point was already converted, but had not peace with God. He had been quickened by the Spirit of God, but did not know the gospel. He was not a formalist, a cold Pharisee, dependent upon rites and ceremonies: he was a man whose outward character, I think, would bear very favourable comparison with that of any person in this building tonight. I do not know whether you are known as "a devout person; one that feared God with all his house" (mark that, for it was apparently a pretty big one), "which gave much alms to the people, and prayed to God always." He was a devout man, a God-fearing man, a benevolent man, and a prayerful man, and yet he was not saved.
But, you say, if that does not save a person, what will? Not all that, nor ten thousand times all that. That does not save. Yet, you say, you said yourself that he was a converted man. Yes, I believe he was: he was a man who had turned to God; but, when I say "saved," I use the word advisedly. I use it, as it is used in the New Testament, and by being a saved man, I mean, a man who is in the liberty of the new creation: a man who knows the liberty of the grace of God, who knows what it is to be brought to God: a man who knows that his sins are forgiven, that he is accepted of God, is His child, and can call Him Father. That is what Cornelius did not know. Oh, you say, could a man be converted, and yet not know that he was saved? There are hundreds of men, who are truly converted, and yet do not know that their sins are forgiven. Possibly, friend, you are one of them: you have had longings after Christ, and light for weeks past: you fear God: you are longing deeply to possess the blessing of God, you have turned your back upon the world, and still you have not peace. Why? You ought to have it. The fact is, you are not simply resting on Christ's finished work, and God's testimony to His satisfaction therein. That alone gives the soul solid peace.
Now Cornelius was a man who had never heard the gospel. You must not compare Cornelius with the men of Edinburgh; because the centurion was a man who had no right, or rather, felt that he had no right to salvation. He knew God was the God of the Jews, and he knew that salvation was of the Jews, and he no doubt said, I am a Gentile, and therefore have no right to it. You see, his very uprightness and honesty were the source of his distress. Look then how God loves to meet this anxious man! Look how He desires to meet the man who is in earnest. He takes all this trouble, if I may so speak, in order to bring liberty, and blessedness, and peace to this troubled man. My friends, I would that you knew the deep interest God takes in man's salvation. Oh! worldly man, you who think little of the Lord, if you only knew the love of His heart, and the infinite interest He takes in you, your heart would be captured by Him right away.
Look at this chapter! He sends an angel to the troubled man, and sends a vision to His praying servant, Peter.
In this chapter you have Cornelius on the one hand, praying at Caesarea, and another man praying forty miles away, on the house-top. Both are being prepared by God for each other. He sends to the anxious man an angel, and says, so to speak, I know what you want, Cornelius; you will get what you want. And He says, by the vision, to Peter on the house-top, I want you to get rid of all your old Jewish ideas; you must get all your old ideas and prejudices knocked out of your head, and you must go and do what I bid you. "Thus He prepares the servant, ere he comes in contact with the poor troubled Gentile, to whom he is to carry the gospel news.
Now a man may be turned to God, and his soul be quickened by the Spirit of God, he can have holy desires, and he may fear God, and yet he may never really know what the gospel is. You may say to me, "What is the gospel?" I think this chapter will unfold it; but, in brief, let me tell you what I mean by the gospel. The gospel that comes from God now is the fruit and result of the atoning work of the Lord Jesus Christ, and, by His grace now upon earth, there is the ministry of the Spirit of God, come down from heaven, a true and blessed witness who tells of forgiveness, and of redemption, and assures you that, if believing in the Lord Jesus, you are saved, that your sins are forgiven, and that you are a child of God. You, as a child of God, receive the Holy Ghost, who brings you into the joy, and the satisfaction that is provided by Christianity.
My idea of a Christian is that of a man who is brimful of joy from one year's end to another. You say, I do not meet many of that stamp. I admit that; but you have not got the right stamp before you. Look at Paul: you find him full of joy and peace. But you say, he was an apostle. I know that, but it was not his apostleship that filled him with joy; it was the knowledge of Christ dwelling in him. And what will fill your heart with joy? What has filled my heart with joy during these seven-and-thirty years? Christ! Aye, and He will fill your heart with joy: He will forgive your sins, where you sit, and He will save you, and will let you know you are saved through the work He has accomplished for you.
Let us see how Cornelius received blessing. He was in prayer, and evidently saw a vision, about three o'clock in the afternoon, of "an angel of God coming in to him, and saying to him, Cornelius" (ver. 3). He was frightened; so is every man when God gets near to him. Sinner, you will get frightened when you have the sense that God draws near to you. Jacob was afraid when God drew near that night on which he was left alone by the river's side. The shepherds were afraid when the angels were sent to tell them of the birth of the Saviour. Cornelius was afraid. There never was a man yet who was not afraid when the Lord drew near, because conscience tells him — just what conscience told me — that a sinner in his sins is not fit for God.
The angel addresses Cornelius, and says to him, "Thy prayers and thine alms are come up for a memorial before God" (ver. 4). Cornelius says, "What is it, Lord?" He is evidently surprised that God should visit him. The greatest surprise that ever I got in my life was when the Lord saved me. I never had such a surprise all my days as on the night the Lord saved me; and I believe if you get God's salvation now that it will be a most wonderful surprise to you, that He in His great and infinite goodness should save a wretched, ruined sinner like you.
I understand the man's feelings as he expresses them in these words, "Lord, what is it?" And what is God's answer? This, if I may put it into other language, I am going to bless you, Cornelius. He says: "Thy prayers and thine alms are come up for a memorial before God. And now send men to Joppa, and call for one Simon, whose surname is Peter: he lodges with one Simon, a tanner, whose house is by the sea-side: he shall tell thee what thou oughtest to do" (vers. 4-6).
And when Simon does come to the troubled soul, do you observe what he does tell him to do? "To him give all the prophets witness, that through his name, whosoever believes in him shall receive remission of sins" (ver. 43). What the messenger says to the troubled soul, when he gets into his presence, is, Believe in God's Son: believe in the One, whom the world has refused, and whom God has taken into glory. He tells him, that all the prophets bear witness to this blessed truth, that from Christ he will obtain forgiveness of his sins, and all he has "to do" is to believe in Him.
Well, what do I find the man does? The angel departs, and Cornelius, now in downright earnestness of soul, immediately calls "two of his household servants, and a devout soldier of them that waited on him continually, and when he had declared all these things to them, he sent them to Joppa" (vers. 7, 8). Not tomorrow — no! that same day, clearly. They went off that day. Cornelius was not like a great many lazy sinners nowadays, who put off the salvation of their souls until tomorrow. I met a young man of this sort some time ago, perhaps he is here tonight. A fortnight ago a friend of his died, and after he came home from the funeral, he said to a Christian: "That young man was converted on his death-bed. Do you believe in death-bed repentance?" "Yes," said the Christian. "Oh! then," said the young fellow, "that is capital, it will do." "What will do?" asked his friend. "I will put off being a Christian till my death-bed." Awful folly!
Friend, I suppose you mean to be converted some day? Do not put it off: no, no, do not put it off till your death-bed. There is only one death-bed repentance given us in Scripture, that no man may presume; but there is one, that none may despair. I have little faith in them. Rowland Hill called them not death-bed conversions, but death-bed fear of hell and damnation. He was not far wrong.
Oh! you say, I believe in the goodness of God. Yes, He is good, and infinitely better than you dream of, but is that a reason for you to refuse His grace, and put off your soul's eternal salvation till the moment of your death-bed? If so, you are like another foolish man I have heard of, and he was like you. He procrastinated, and he meant to come to Christ in the future, for he believed in the goodness of God. He was surrounded by Christian friends, and they often pleaded with him to come to the Lord. But he was like you — he loved the world, and he would do anything for the world. His world was pretty much wrapped up in the hunting-field: he did not care for anything but hunting. When his friends pressed on him to turn to God he replied: "Would not God bless me if I went to Him on my death-bed? I believe so in His goodness that if I were to turn to Him on my deathbed, the Lord would have mercy upon me; and then I will do it." So he calmed his soul, if troubled somewhat by the words that were spoken to him. One day he was hunting: he was on the back of an exceedingly fine horse, and, to make up to the hounds, he had to take a hedge. His horse sprang through the brushwood, but on the other side was a flock of sheep, which were frightened as he came over. They scampered right and left, and the horse was startled. It stumbled, and threw its rider. As he fell he was heard to say — not "God have mercy upon me" — not a bit of it! what he said was, "Devil take ye." He broke his neck, and died on the spot. Oh! procrastinating sinner! remember the last words of this man — so like you — were not, "God have mercy upon me," but, "Devil take ye." The devil did not take the sheep, but he took the godless rider that day. Take care, that he does not take you, my friend.
Now, Cornelius may well teach us a lesson here. He sends at once, when he learns that there is one who can tell him the way of salvation. That is what he wanted, and immediately he despatches his servants on their journey of about forty miles, for that was the distance between Caesarea and Joppa.
"On the morrow, as they went on their journey, and drew nigh to the city, Peter went up upon the house-top to pray, about the sixth hour." It is interesting to see how the Lord prepares His servant, in this chapter. He let him fall into a trance: he was not asleep; he was in a trance. God was going to teach Peter a wonderful lesson, and he sees this remarkable sheet coming down from heaven. Mark, it says, "And saw heaven opened." We find heaven opened four times in the New Testament.
Do you know that heaven is opened just now. It was once opened for the Father to look down upon Jesus on earth; to see the man in whom God delighted (Matt. 3:16). In the seventh of Acts it is opened for faith to look up, and see Jesus there. Stephen says, "Behold, I see the heavens opened, and the Son of Man standing on the right hand of God" (Acts 7:56). Here Peter "saw heaven opened, and a certain vessel descending to him," [Acts 10:11] and he says in the eleventh chapter, when he tells the story to the Church at Jerusalem, "And it came even to me" (Acts 11:5). It was a lesson to him; and there comes a lesson from heaven to you tonight, that Jesus is willing to save you where you are in this hall. "And it came even to me" — what was the lesson? That there was no limit to the grace of God. Peter "saw heaven opened, and a certain vessel descending to him, as it had been a great sheet, knit at the four corners, and let down to the earth wherein were all manner of four-footed beasts of the earth, and wild beasts, and creeping things, and fowls of the air" (vers. 11, 12). I do not doubt but that God here presents man as he is in his natural characteristics, but saved by grace, and taken to heaven. The fourth time heaven is seen opened is in the Book of Revelation, when the King of kings comes to reign, and all His saints with Him (Rev. 19:11).
But Peter says presently, "The vessel was received up again into heaven." God takes it back again, and that is just what one would expect; nothing goes into heaven but what comes out of it. And how, you ask me, do you expect to get to heaven? I will tell you. My Saviour came for me: He bled and died for my sins, and put them away, and the Spirit of God has begun His work of grace in my soul. Were it not so, I could not go to heaven. There is nothing in either you or me that fits us for heaven. "That which is born of the flesh is flesh," the third of John tells us; that is to say, man as such cannot go into heaven; he must be born again; there must be a work of God's Spirit in his soul, as well as a work wrought for him by the Son of God on the cross. The contents of the vessel just show us that there is no limit to the grace of God. His grace meets and saves the most unlikely, and the apparently most unsuited.
God's grace prepares Peter for the work before him, but he does not learn his lesson very quickly. He finds out, however, that the goodness of God is going to override all his former ideas, and that the blessed gospel is going into other spheres than the Judaism, of which he had thought so much. This lesson he does not learn immediately, for he "doubted in himself what this vision that he had seen should mean" (ver. 17). But "while Peter thought on the vision, the Spirit said to him, Behold, three men seek thee." Observe "the Spirit said," — it is not an angel who speaks. When it is a question of dealing with the soul, and carrying the truth to the soul, the Spirit speaks. The Holy Ghost whispers to Peter, and what does He say? "Behold, three men seek thee. Arise, therefore, and get thee down, and go with them, doubting nothing, for I have sent them" (vers. 19, 20). Immediately Peter goes down. There are the men at the door. They have found out the place where Simon lives: they are in search of the Evangelist, and meantime the Evangelist has been prepared by God to carry His message to an anxious soul.
Ah! friend, are you anxious tonight? Good! it is a sweet message I have for you — Pardon, Peace, Salvation! Nothing is so charming as preaching the gospel. Why do you preach? I have been asked. Well! I tell you honestly, I cannot say that I was bred, trained, or authorised by man to preach, but I have the sense of God's love to me, and I want you to share it, that is why I have asked you to come here tonight. Immediately you know what the grace of God is, you want others to have that knowledge too: you want others to have the same joy as yourself. Even Cornelius illustrates this, for when he knew he was to hear the way of salvation, he "called together his kinsmen and near friends" (ver. 24) to share the blessed news with them.
But let us follow Peter down from the house-top. He goes to the door and asks the men," What is the cause wherefore ye are come?" (ver. 21.) Peter greatly interests me: although he is so slow at his work. He had not fully realised this new departure in the ways of God. To this interrogation the three men reply: "Cornelius the centurion, a just man, and one that fears God, and of good report among all the nation of the Jews, was warned from God by an holy angel to send for thee into his house, and to hear words of thee" (ver. 22).
The ways of God with souls as presented in Scripture are beautiful, and you who are Christians, I think, will enjoy what I am now going to speak about, if you have not noticed it before. When God was going to send the gospel of His grace to the Gentiles, whom does He select as the first vessel, if I may so speak, into which He will put His treasure? It is not a scandalous man: it is not a blasphemer, or a cursing man. That would have been to awaken Jewish opposition. He selects a man, concerning whom the Jews had already issued a "good report," since he was a "devout man." Ah! said God, you go and tell that devout man the gospel, Peter! That is the man whom God selects here. If we be spared till another Lord's Day evening, we will see how His grace will go out to a man, who has not one single thing to commend him.
It is beautiful to see how the Lord sends His messenger to one whose outward character was blameless: even the Jews bear record of him, that he was a just man, and one that feared God, notwithstanding the fact that he was a Gentile, and a Roman, and very likely oppressing them in the execution of the laws of his master, the Emperor of Rome, — still the whole nation said he was a just man. He had not the gospel, it is true; but he was now to get it.
Peter lodges the strangers over-night, "and on the morrow Peter went away with them, and certain brethren from Joppa accompanied him" (ver. 23). His action in taking them was remarkable, for I should not have said that caution was Peter's leading feature; but on this occasion for manifest reasons he does not like to go into the business alone. Three men come to ask for the truth, Peter takes with him six brethren to be witnesses of what was going on. I have often said I should have liked to have been the seventh man to go down with Peter that day, and see the wonderful tide of blessing that was about to roll into the house of Cornelius. If any one here is bound on a gospel mission, and you are sure you are going to a household of downright anxious souls, if you will invite me, I will go with you. I do not know anything more charming than the scene I get in this chapter, as Peter goes down to this household of anxious souls: it is a most lovely sight.
It was clearly a two days' journey from Joppa to Caesarea, and four days had elapsed from the time the men were sent off for Peter, until he returned with them to Caesarea. "And Cornelius waited for them, and had called together his kinsmen and near friends. And as Peter was coming in, Cornelius met him, and fell down at his feet, and worshipped him" (vers. 24, 25). A wonderful thing that for a Roman to do: they would scarcely even salute a stranger, that is a well-known fact But here, Cornelius actually falls at the feet of this messenger, who, he knew, was the messenger of God to his soul: this only shows how earnest the man was. "But Peter took him up, saying, Stand up: I myself also am a man" (ver. 26). You are a man, and so am I: we are on the same level. "And as he talked with him, he went in, and found many that were come together" (ver. 27). You will always find it so: when a person is interested in the truth, about which they are not clear, they want some one else to come and hear about it too. I should not be surprised if there are men in this hall, who though not clear themselves as to the gospel, have said to others, Come along with us: we will go and hear what this preacher has to say. That was exactly Cornelius' position: he had not got the light himself, but he could say, I know I am going to get it: I have had a message from God, and light is coming, so he fills his house with his friends and kinsmen.
Peter "found many that were come together." I have seen many audiences, and I have seen many a multitude; but, to tell the truth, the one multitude that chains my eye, and charms my heart, is a multitude of men and women that want to hear about Christ. People have often said to me, "Have you been to the picture gallery this year yet, doctor?" "No!" "Why not?" "Because, I should not see the pictures I want to see." "And what are you looking for?" "I will tell you the pictures I want, — one is a company of happy saints enjoying Christ, and desirous to hear more of Him, and the other is a company of anxious sinners, longing to find Him. If you can show me these pictures I will come."
Here we have this beautiful picture, — a company of anxious souls, waiting to hear about Jesus, and in comes the preacher. He begins with a word of explanation: "Ye know how that it is an unlawful thing for a man that is a Jew to keep company, or come to one of another nation; but God has showed me that I should not call any man common or unclean. Therefore came I to you, without gainsaying, as soon as I was sent for: I ask therefore for what intent ye have sent for me?" (vers. 28, 29.) I must say that I never quite understood that question. I cannot understand a man, who knows the grace of God, and is in the presence of anxious people, asking, "For what intent ye have sent for me?" I think, if I got into such a gathering, I should know, and I would say, I know what you want; you want the gospel: the Lord help me to give it to you.
Cornelius stands up, and tells his story. He merely says, An angel came to me while I fasted, and prayed, and told me what to do, and immediately I did it. Perhaps, some of you thought I was going beyond Scripture when I said, Cornelius sent his servants off immediately; but I was not, for I read: "Immediately therefore I sent to thee; and thou hast well done that thou art come. Now therefore are we all here present before God" (I wonder if these words can be applied to the company here tonight) "to hear all things that are commanded of thee of God" (ver. 33). He had the sense that they were to hear from God, and that this servant of God had to declare His message.
"Then Peter opened his mouth, and said, Of a truth I perceive that God is no respecter of persons: but in every nation he that fears him, and works righteousness, is accepted with him. The word which God sent to the children of Israel, preaching peace by Jesus Christ: (he is Lord of all:) that word, I say, ye know" (vers. 34, 35). Peter was evidently perfectly conversant with what had taken place: that Cornelius and his household had heard some of the truth in regard to Israel; but, as I said before, whatever blessing or inheritance was Israel's, Cornelius, being a Gentile, in his uprightness of character, knew did not belong to him. He longed for peace, but thought only the Jew could get it. But what does the gospel bring to all now? Peace! When the Saviour was born, on that very day, the heavenly messengers proclaimed, "Glory to God in the highest, and on earth peace." What a priceless boon to weary sin-burdened souls! Peace! Let me ask you, Have you peace? Do you possess peace? Are your sins forgiven? Are you clear with God? Are you clear that you have escaped judgment? Answer these questions.
Beware of a false peace: I cannot deny that there are many men living in this city today, who have a false peace, for "when a strong man armed keeps his palace, his goods are in peace" (Luke 11:21). What does our Lord mean by these words? I think I understand. That palace is the world, and the strong man, who has his goods in peace, is the devil: he keeps his goods in peace. Young man, were you never troubled about your soul? Certainly not; why should I be? Your answer just illustrates this scripture, "When a strong man armed keeps his palace, his goods are in peace." The devil, let me tell you, has an uncommonly good, a very diversified, a splendid armoury. He does not hold every one with the same suit, if I may say so. He knows how to meet every one. He will give you what you want.
He will hold some with the wine-cup; others, he will snare with a pack of cards; others, he will entangle with the theatre, or, it may be, with the novel, or the love of gold, or the power of lust, or the charms of knowledge, or something of that sort. You have never perhaps felt sorrow for your sins; nor will you if he can keep you from thinking of these sins, and of the serious fact that you are a sinner. He will try all he can to keep you from being awakened to the fact that you are a guilty man, and by all means in his power rob you of the blessing of being born again, and brought to God. For many a long day a man may go on in false peace, thinking all is right, when all is wrong, for mark, "When a strong man armed keeps his palace, his goods are in peace." That is a false peace; the devil's lullaby for souls deceived by sin, and oft-times helped hell-ward by a Christless religion. Thank God! if you are troubled now about your sins and your lost estate. Better far is it for a man to be in soul-trouble now, and thus get the peace which God gives, than to go on through life in the delusive peace which the devil ministers, only to wake up in eternity to the awful discovery that the peace was a fraud, and that God's judgment of sin is everlasting.
What we have before us in this scripture, is God's peace — peace by Jesus Christ — the peace of the weary — the peace of the troubled — the peace that God alone can give. And what is that? The knowledge that He has nothing against me, and that there is nothing between Him and me; that the claims of His infinitely holy throne have all been met in regard to myself, and my sins, and I can look at that throne with the sense, I am perfectly fit for it; — I am ready to stand before it. You say, How? Because He is pleased with what I have done? No! But because of the finished work of Christ. The knowledge of that work has let me see that there is not a single thing left between the infinitely holy God, and the infinitely sinful man, whose sin has been divinely and definitively met by the atoning death of the blessed Son of God. Christ took my place in death and judgment, that God might give me His in life and glory. When that knowledge enters the heart, peace, like a river, surges through the soul; and that is the peace I have got.
But you say, Have you never any doubts? Doubts! What should I have doubts about? I do not doubt that by nature I am a guilty, godless, hell-deserving sinner, and till Christ met me I was bound there: I have not a doubt about that. Have you, as regards yourself? But since grace met and saved me, by the work of Another, why should I have a doubt? Have you any doubts, my friend? If so, I hope the Lord will dispel them tonight. If not saved you are on your road to hell; there can be no doubt as to that surely. If grace does not deliver you from the grip of Satan and the power of sin, you will spend eternity there. Oh, you say, I do not believe in such a place. You will have to believe it yet, mark that, my friends. You will be converted some day on that point, depend upon it. See to it that it be not too late.
That is a fine stratagem of the devil to tell you that there is no judgment — no hell — no punishment hereafter. The pathway of Christ refuted that folly. Jesus, the Son of God, came down from heaven to earth, and died to deliver men like you and me from hell. He agonised on the cross that He might rescue me from the consequences of my sin, and blessed be His name, He has rescued me! Why do you not allow Him to rescue you tonight? "He is Lord of all." Not merely of the Jew, but of the Gentile as well. "He is Lord of all." Lovely word! He is my Lord: the time was when I was under another master, and I served him faithfully, but now my master is changed. Time was when I had a bad master, and he had a very good servant. But now, I have an infinitely blessed Master, and He has a poor servant. Thank God! He is my Lord. Can you say the same? Do not be ashamed to say it.
A young woman came to me the other day, and said, "Four and a half years ago I was converted through your preaching, but I was ashamed to confess Jesus." "Ashamed of Jesus! Ashamed of the Lord! And what are you ashamed of now?" I asked. "Oh," said she, "I am ashamed now to confess that I ever was ashamed to own Him." Are you, my friend, ashamed of Jesus: ashamed to own your Lord: ashamed to own the Son of God? Wake up! wake up! There is an immense privilege open to you, to be on the Lord's side. "But," says somebody, "I am such a sinner." Never mind that: the deepest-dyed sinner may be saved by Jesus' grace. Let Him save you, and deliver you, and send you through this world as a witness of what grace can do.
People sometimes think it a poor thing to be a Christian. I think it a paltry thing not to be one: that is my decided conviction, and I advise every young man without any further delay to yield himself up to Him this evening, and be on His side, out-and-out I do not like half and half work — a backboneless kind of Christian is no good at all. Such are like the salt the Lord speaks of; they are of no use for the field, and of no use for the dunghill (Luke 14:34-35). There are a good many of this kind in the professing Church. They do not do the Church any good, and they do the worldling much harm, for their inconsistency and apathy encourage men in unbelief; in fact, they are stumbling-blocks over which sinners stumble into hell. They have too much of the world to really enjoy Christ, and witness for Him, and their consciences will not let them go the whole way in the world. A young convert said to me this morning, "I like to see the people of the world downright." "So do I," I replied, "and you can tell them that hell is the end of their journey." "And, sir," said he, "I like to see a Christian out-and-out." That is just exactly what I like. I want it for myself, and I want you to be out-and-out too.
Having announced Him as "Lord of all," Peter goes on to tell the history of Jesus, and unfolds three great truths — God with us; God for us; and God in us. First of all, you find the truth of God with us: "How God anointed Jesus of Nazareth with the Holy Ghost, and with power; who went about doing good, and healing all that were oppressed of the devil; for God was with him. And we are witnesses of all things which he did, both in the land of the Jews, and in Jerusalem: whom they slew and hanged on a tree" (vers. 38, 39). There you see the fulfilment of the scripture, "A virgin shall be with child, and shall bring forth a son, and they shall call his name Emmanuel, which being interpreted, is God with us" (Matt. 1:23).
Then Peter, from verse 40 to verse 43, brings out the truth, "God for us," while verse 44 gives us the truth, "God in us." "God for us" is shown in the death of Christ, and all the consequences of blessing which accrue to us from it. As the Holy Ghost falls upon all this assembly (ver. 44), we see the truth of "God in us." You must not forget that the Christian is a man in whose body the Holy Ghost dwells; and therefore it is a very solemn thing to be a Christian.
Just a word or two then, as to verse 40 and onwards. "Him God raised up the third day, and showed him openly." In the moment of His death Christ wrought atonement, when He bore the sinner's sins, and was made sin that we might escape its consequences. He sacrificed Himself, and thus infinitely glorified God; and what was the result? God raised Him up. I can tell you therefore of a risen, triumphant, victorious Saviour. That is the Saviour I know. He triumphed over sin, Satan, death, the grave, and the power of darkness; and as the risen man He lives before God. "Him God raised up the third day, and showed him openly; not to all the people, but to witnesses chosen before of God, even to us who did eat and drink with him after he rose from the dead." There was unmistakable evidence of the reality of His Person. "And he commanded us to preach to the people, and to testify that it is he, which was ordained of God to be the judge of quick and dead."
Observe, my friend, if you do not let Him save you, He will have to judge you. And you say, Will He not judge you too? No! blessed be His name, never! Why? Because He is my Saviour; that is the whole point. Judgment will not be a mockery. I quite admit, I shall have to give account of my walk and ways as a Christian; but, when you talk about judgment, that raises the question of the imputation of guilt; and do you think He is going to impute guilt to those for whom He died? Let Scripture answer: "Who shall lay anything to the charge of God's elect? It is God that justifies. Who is he that condemns? It is Christ that died, yea rather, that is risen again; who is even at the right hand of God, who also makes intercession for us" (Rom. 8:33-34). I have no fear of judgment; — fear is gone out of my heart, because Christ is my Saviour. Who shall lay anything to the charge of God's elect? is the challenge. Let Satan accuse; the devil will do it if he can, but God will justify the believer, and He will silence the accuser. Christ died, and He died for me that I might be delivered, and saved; and, what He died to do, blessed be His name, He has done. He died for me that He might be my Saviour, and He has saved me, for I trust Him. Do you not trust Him? If so, you are saved by Him, as the fruit of His perfect love, and finished work. Well wrote Steele —
"He took the guilty culprit's place,
And suffered in his stead;
For man (Oh miracle of grace!)
For man, the Saviour bled."
As the righteous outcome of His finished work, Peter now declares: "To him give all the prophets witness, that through his name whosoever believes in him shall receive remission of sins" (ver. 43). That is the very thing I wanted; and the very thing you need — Every prophet bears witness that the one who trusts Jesus has forgiveness of his or her sins. Are these not sweet words? "To him give all the prophets witness, that through his name whosoever believes in him shall receive remission of sins." And what did the listeners to that lovely gospel do? They were dear, simple people, and they believed the gospel, for "while Peter yet spake these words, the Holy Ghost fell on all them which heard the Word." This was the fulness of grace indeed. The triumph of grace is seen here.
There is nowhere in the ways of God with man, in which His grace sparkles with greater brilliancy, than in this scene, where the Gentile who had no claim on, and no link with Him, hears the gospel, in all its fulness, and the Holy Ghost falls on the believer, without either baptism, as in the case of the Jew (Acts 2:38), prayer, as in the case of the Samaritans (Acts 8:15), or laying on of hands, as in the case of the Jewish proselytes at Ephesus (Acts 19:6). The hearing of faith secured the blessing when the "words" Peter spake fell from his lips.
"Send men to Joppa and call for Simon, whose surname is Peter, who shall tell thee words, whereby thou and all thy house shall be saved" (Acts 11:13-14), was the command Cornelius received, and the obedience of faith soon heard the words of life. I sometimes say that the little letter K is responsible for a good deal of mischief WORDS and WORKS differ only in one letter. Knock out the D, and put in the K, and there is all the difference possible. WORDS were what Cornelius was to hear. He was not told to do any WORKS. Have you thought you had to do some WORKS, to obtain salvation? Not so, my friend. What you need is to hear words. You must knock that letter K out of your religion, or you will never be saved. But I hear some one say, Must I do nothing? Nothing, Christ has done everything; that is the whole point "Who shall tell thee words, whereby thou and all thy house shall be saved," is God's way of salvation. When saved you are careful to "maintain good works," not in order to salvation, but just because you possess it.
Peter told them lovely words. What were the words? Listen! "To him give all the prophets witness, that through his name, whosoever believes in him shall receive remission of sins." The forgiveness of sins, through the precious name of the Lord Jesus Christ, is the present possession of every soul, man or woman, that receives Him, and the Holy Ghost seals the faith of the believing one — He comes, and indwells all such. Peter's address was very short; but it had no sooner fallen from his lips, than the "Holy Ghost fell on all them which heard the word."
The Holy Ghost always seals the faith of a soul that trusts in Jesus. How then does a man get the Holy Ghost? By believing. He not only gets the forgiveness of his sins, but the Holy Ghost comes down and seals his faith. If I were you, I would not go away from this place without having the knowledge in your soul, that your sins were forgiven, and that you had received the Holy Ghost. It is your portion if you believe in the Lord Jesus Christ. Hear what Paul says, "In whom ye also trusted, after that ye heard the word of truth, the gospel of your salvation: in whom also after that ye believed, ye were sealed with the Holy Spirit of promise" (Eph. 1:13). When a man buys sheep, he is only wise to put his own mark upon them: but observe, the mark does not make the sheep his: the purchase-money makes them his. He puts his mark upon them, to show that the sheep do belong to him, and so God marks every one of His children by giving them the Holy Ghost. He has put His mark on every one in this hall that really believes in Jesus.
And you, my friend, can soon find out if you have His mark upon you; if you truly know that Jesus loved you, and died for you, and you simply trust in Him, I believe you have the Holy Ghost sealing the forgiveness of your sins. And now, I want you to join the choir tonight. What choir? The choir of the ransomed. People sometimes say, We have been asked to join the choir. Are you converted? I ask. If not, you cannot be in the choir of the redeemed, and that is the choir I want you to sing in. Every one who really believes in the name of Jesus, let him join in singing —"Come sing, my soul, and praise the Lord,


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07:00-08:30: Registration, Breakfast, and Networking. Thank you, CDO Club!
08:30-08:45: Keynote: David Mathison: Curator at CDO Summit
08:45-09:00: Welcome: Jay Rosenzweig: CEO of Rosenzweig & Company Inc.
09:00-09:15: Opening Remarks: Lisa Rowsell: Managing Director, Canada, Financial & Risk Business at Thomson Reuters
09:15-09:45: Keynote: Jessie Adcock: Chief Technology Officer of the City of Vancouver
09:45-10:15: Keynote: Hillary Hartley: Chief Digital Officer and Deputy Minister for Digital Government at Ontario Public Service
10:15-10:45: Mid-Morning Break Thank you, CDO Club!
10:45-11:15: Keynote: Cindy Forbes: EVP & Chief Analytics Officer at Manulife
11:15-12:00: Panel: Mining Real Value From Your Data Lake
12:00-13:30: Lunch Thank you, CDO Club!
13:00-13:15: Luncheon Keynote: TBA
13:15-13:30: Luncheon Keynote: Erin Janus: Video Journalist at YouTube
13:30-13:45: Impact Keynote: Amy Yee: Chief Digital Officer at Health Standards Organization (HSO)
13:45-14:00: Impact Keynote: David Corrigan: CEO of AllSight
14:00-14:15: Impact Keynote: Ana Serrano: Chief Digital Officer at Canadian Film Centre
14:15-15:00: Fireside Chat: Building Globally Competitive AI in Toronto
15:00-15:30: Mid-Afternoon Break Thank you, CDO Club!
15:30-15:45: Fireside Chat
15:45-16:00: Impact Keynote: Ash Fontana: Managing Director at Zetta Venture Partners
16:00-16:30: Keynote: Khalid Al-Kofahi: Vice President, R&D at Thomson Reuters
16:30-17:00: Keynote: Ted Graham: Head of Open Innovation at General Motors
17:00-17:05: Wrap up: Jay Rosenzweig: CEO of Rosenzweig & Company Inc.
17:05-END: Networking Cocktail Reception Thank you, CDO Club!


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NBC's "Today" got its African American quarterbacks confused this morning.
The program had an interview with Philadelphia Eagles quarterback Michael Vick, who has a new memoir out. Vick was one of the top quarterbacks in the NFL, and almost lost it all when he was convicted for his involvement in an illegal dog-fighting ring. After getting out of prison he was given a second chance at football by the Eagles.
Given his superstar athlete status, and his time in the news for the dog-fighting, Vick is one of the most recognizable people in the U.S. That did not stop NBC from showing b-roll of a completely different quarterback, however.
The quarterback in that video is not Vick, but rather former Eagles QB
Vince Young (as first noted by Guyism) Update: Guyism now reports that it was Jerrod Johnson, not Young. While they are both African American, and both played for the same team, Vick wears number seven, not eight, and Vick is (quite famously) a lefty, not a righty, as seen in the clip.


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RALLY For a lively, welcoming and popular Mediterranean - 23/06/19 at 12:30, Marseille
Sunday 23/06/19 at 12:30
MUCEM, 7 Prom. Robert Laffont, 13002 Marseille
While Emmanuel Macron organizes his Meeting of 2 Shores to celebrate the Nicolas Sarkozy's Mediterranean, the States General of Marseilles and the International Alliance of the Inhabitants come to claim a living Mediterranean, welcoming and popular, denouncing the dead in the Mediterranean and demanding policies of reception and solidarity.
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It is probably moving enough to make the branches on the trees sway slightly.
The weight of this air pressing down all around the earth produces air pressure.
If you live high up above sea level, or even if you go up to the top of a tall skyscraper, the air pressure is less. This is because there is less air above you, and therefore less air pressure.
On the surface of the earth, or near it, air always moves from areas of high pressure to areas of low pressure. Temperature has a great effect on air pressure. As warm air rises, it produces an area of low pressure near the ground. As the air pressure changes from place to place, and from day to day, it helps move air across the earth's surface all the time. As cooler air moves down, it leaves behind an area of high pressure.
The instrument used to measure changes in air pressure is called a barometer. If you have one at home, it is probably an aneroid barometer. There's a needle behind a glass-covered dial marked "Fine," "Fair" and "Stormy." If you tap the glass lightly in the morning, the needle points to the weather you can expect that day.
Inside the aneroid barometer is a metal box, or chamber, from which almost all the air has been removed. The metal of the chamber is so thin that small changes in the air pressure outside it make the metal bend. This makes the needle turn round and point to a new position on the dial.
A mercury barometer measures the air pressure more accurately. A long, glass tube is filled with mercury, a silvery liquid metal. The tube is sealed at one end, and placed open end down in a small dish of mercury. Some of the mercury stays in the tube. It is held there by the air pressure at the surface of the mercury in the dish. As the air pressure changes, the column of mercury moves up or down. A scale beside the tube shows the pressure measurements.


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There should be a word – one of those big, pretentious German words – for that joyous moment when you realize that you're one of eleven billion people, and don't have to be special. I first experienced this in my early thirties, and at first I was tempted to be depressed about it. Fortunately I had some preparation from the Gospels that helped me negotiate the ego blow of discovering that I was not, nor would ever be, the center of the world. I had been assured that God was counting every hair on my head, and even if I would never be known on television or in the world of literature, I would be intimately known to God. Just like everyone else.
Peter and John have more reason to think of themselves as special than I ever did. After all, they're healing people in the temple and helping the lame to walk. And the crowds that surround them are amazed. Yet Peter refuses to take credit. His response is essentially egoless. It wasn't me, he says, but Jesus. And in this simple encounter, he set the pattern for the church. He said, in effect, that the Beloved Community of the church had only one charismatic leader, and that leader is Jesus Christ, and the rest of us should be content to simply feel the hairs on our heads counted by the fingers of a gentle God.
Peter invites people to know Jesus, even those who rejected and crucified him. He does this because he realizes that God loves and knows them just as much as God loves and knows the disciples. All things, he says, all miracles, all history, all stories, point to Christ. We don't need leaders who are sunk in their own egos, making choices and exerting power in order to keep those egos defended. We need leaders who want to become thin, almost transparent with grace, like saints in stained glass windows. We want to be able to see through our leaders and see the light of God shining both in them and outside of them. For Peter, and for the Beloved Community, a true leader is exactly the opposite of the Pharisee in the parable of the Pharisee and the Publican. Instead of saying "I thank you God that I am not like other people," a true leader says "I thank you God that I am exactly like other people, as full of trouble and grace as them, as silly and as wise."


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Please join Dave Matthews Band's initiative to support the Local Food Hub and the BAMA Works Fund by requesting VIP Packages for the John Paul Jones Arena shows on December 14 and 15. The proceeds from the sale of the VIP packages will be contributed by DMB to both organizations.
Dec. 14 The Local Food Hub is an innovative Charlottesville-based nonprofit working to connect families, farms, and food grown close to home.
Dec. 15 BAMA Works, DMB's charitable fund administered by the Charlottesville Area Community Foundation, supports a wide variety of non-profit organizations locally, nationally and internationally. VIP packages are available to Warehouse members. VIP Packages are $275.00 per person (plus applicable convenience fees) and include the following:
- - one concert ticket (choice of Reserved seating or GA Floor Standing**)
- - one GA parking pass
- - access to an exclusive pre-show hospitality area with complimentary hors d'oeuvres, beverages and a fund-raising silent auction
- - one limited-edition souvenir laminate
*Package details subject to change without notice. **No dedicated VIP viewing area on the arena floor.


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Taylors Lake
Serving Australia and its suburb areas since decades Building property inspection Melbourne is being considered among one of the reputed Pre Auction Building and property Inspection across Taylor lake who is also member of the HIA -housing industry Association for over 15 years. Being equipped with highly qualified staff of building and pest inspection we cover all the below mentioned inspection services:
- pre- purchase inspections
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Along with all of these attributes there are many other factors taken in account when it comes to skilled property inspection Taylor Lake. Among which the top three are:
- Size of the dwelling
- Location and the type of construction
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Therefore, you can entirely depend on us as we are fully insured and guaranteed to the highest standards under AS4349.1:2007 (Pre-Purchase) and AS4349.3:2007 (Pest).
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Relenza 5mg/dose, inhalation powder, pre-dispensed.
Each pre-dispensed quantity of inhalation powder (one blister) contains 5 mg zanamivir. Each delivered inhalation (the amount that leaves the mouthpiece of the Diskhaler) contains 4.0 mg zanamivir.
Excipients with known effect:
Lactose monohydrate (approximately 20 mg which contains milk protein).
For the full list of excipients, see section 6.1.
Inhalation powder, pre-dispensed. White to off-white powder.
Treatment of influenza
Relenza is indicated for treatment of both influenza A and B in adults and children (≥ 5 years) who present with symptoms typical of influenza when influenza is circulating in the community.
Prevention of influenza
Relenza is indicated for post-exposure prophylaxis of influenza A and B in adults and children (≥ 5 years) following contact with a clinically diagnosed case in a household (see section 5.1 for children aged 5-11 years). In exceptional circumstances, Relenza may be considered for seasonal prophylaxis of influenza A and B during a community outbreak (e.g. in case of a mismatch between circulating and vaccine strains and a pandemic situation).
Relenza is not a substitute for influenza vaccination. The appropriate use of Relenza for prevention of influenza should be determined on a case-by-case basis depending on the circumstances and the population requiring protection.
The use of antivirals for the treatment and prevention of influenza should take into consideration official recommendations, the variability of epidemiology, and the impact of the disease in different geographical areas and patient populations.
Inhaled drugs, e.g. asthma medication, should be administered prior to administration of Relenza (see section 4.4).
Treatment of influenza
Treatment should begin as soon as possible, within 48 hours after onset of symptoms for adults, and within 36 hours after onset of symptoms for children.
Relenza is for administration to the respiratory tract by oral inhalation only, using the Diskhaler device provided. One blister should be utilised for each inhalation.
The recommended dose of Relenza for treatment of influenza in adults and children from the age of 5 years is two inhalations (2 x 5 mg) twice daily for five days, providing a total daily inhaled dose of 20 mg.
Prevention of influenza
Post-exposure prophylaxis
The recommended dose of Relenza for prevention of influenza, following close contact with an individual, is two inhalations (2 x 5 mg) once daily for 10 days. Therapy should begin as soon as possible and within 36 hours of exposure to an infected person.
Seasonal prophylaxis
The recommended dose of Relenza for prevention of influenza during a community outbreak is 2 inhalations (2 x 5 mg) once daily for up to 28 days.
Impaired Renal or Hepatic Function: No dose modification is required. (See section 5.2).
Older patients: No dose modification is required. (See section 5.2).
Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Contraindicated in patients with milk protein allergy.
Due to the limited number of patients with severe asthma or with other chronic respiratory disease, patients with unstable chronic illnesses or immunocompromised patients (see Section 5.1) who have been treated, it has not been possible to demonstrate the efficacy and safety of Relenza in these groups. Due to limited and inconclusive data, the efficacy of Relenza in the prevention of influenza in the nursing home setting has not been demonstrated. The efficacy of zanamivir for the treatment of elderly patients ≥ 65 years has also not been established (see section 5.1).
There have been very rare reports of patients being treated with Relenza who have experienced bronchospasm and/or decline in respiratory function which may be acute and/or serious. Some of these patients did not have any previous history of respiratory disease. Any patients experiencing such reactions should discontinue Relenza and seek medical evaluation immediately.
Due to the limited experience, patients with severe asthma require a careful consideration of the risk in relation to the expected benefit, and Relenza should not be administered unless close medical monitoring and appropriate clinical facilities are available in case of bronchoconstriction. In patients with persistent asthma or severe COPD, management of the underlying disease should be optimised during therapy with Relenza.
Should zanamivir be considered appropriate for patients with asthma or chronic obstructive pulmonary disease, the patient should be informed of the potential risk of bronchospasm with Relenza and should have a fast acting bronchodilator available. Patients on maintenance inhaled bronchodilating therapy should be advised to use their bronchodilators before taking Relenza (see section 4.2).
Zanamivir inhalation powder must not be made into an extemporaneous solution for administration by nebulisation or mechanical ventilation. There have been reports of hospitalised patients with influenza who received a solution made with zanamivir inhalation powder administered by nebulisation or mechanical ventilation, including a fatal case where it was reported that the lactose in this formulation obstructed the proper functioning of the equipment. Zanamivir inhalation powder must only be administered using the device provided (see section 4.2).
This medicinal product contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Relenza is not a substitute for influenza vaccination and the use of Relenza must not affect the evaluation of individuals for annual vaccination. The protection against influenza only lasts as long as Relenza is administered. Relenza should be used for the treatment and prevention of influenza only when reliable epidemiological data indicate that influenza is circulating in the community.
Relenza is effective only against illness caused by influenza viruses. There is no evidence for the efficacy of Relenza in any illness caused by agents other than influenza viruses.
Neuropsychiatric events have been reported during administration of Relenza in patients with influenza, especially in children and adolescents. Therefore, patients should be closely monitored for behavioural changes and the benefits and risks of continuing treatment should be carefully evaluated for each patient (see section 4.8).
Potential for other drugs to affect zanamivir
Zanamivir is eliminated through renal filtration. Clinically significant drug interactions are unlikely.
Potential for zanamivir to affect other drugs
Zanamivir does not inhibit the cytochrome P450 (CYP) enzymes CYP1A1/2, 2A6, 2C9, 2C19, 2D6, 2E1 and 3A4. Zanamivir does also not affect the renal transporters OAT1, 2, 3 and 4, OCT1 and 2, OCT2-A, OCT3 and the urate transporter hURAT1.
Zanamivir, when given for 28 days, did not impair the immune response to influenza vaccine.
Systemic exposure to zanamivir is low following administration by inhalation; however, there is no information on placental transfer of zanamivir in humans. There is a limited amount of data (less than 300 pregnancy outcomes) from the use of zanamivir in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity (see section 5.3).
As a precautionary measure, it is preferable to avoid the use of Relenza during pregnancy, unless the clinical condition of the woman is such that the potential benefit to the mother significantly outweighs the possible risk to the foetus.
Systemic exposure to zanamivir is low following administration by inhalation; however, there is no information on secretion of zanamivir into human breast milk. A risk to the breastfed child cannot be excluded. A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from Relenza therapy, taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Animal studies indicate no clinically meaningful effects of zanamivir on male or female fertility (see section 5.3).
Zanamivir has no or negligible influence on ability to drive and use machines.
There have been rare reports of patients with previous history of respiratory disease (asthma, COPD) and very rare reports of patients without previous history of respiratory disease, who have experienced acute bronchospasm and/or serious decline in respiratory function after use of Relenza (see section 4.4).
The adverse events considered at least possibly related to the treatment are listed below by body system, organ class and absolute frequency. Frequencies are defined as very common (≥1/10), common (>1/100, <1/10), uncommon≥ >1/1000, <1/100), rare (≥1/10,000, <1/1000), very rare (<1/10,000), not known (cannot be estimated from the available data).
Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.
Immune system disorders
allergic-type reactions including oropharyngeal oedema
Anaphylactic/Anaphylactoid reactions, facial oedema
Nervous systems disorders
vasovagal-like reactions have been reported in patients with influenza symptoms, such as fever and dehydration, shortly following inhalation of zanamivir.
Respiratory, thoracic and mediastinal disorders:
bronchospasm, dyspnea, throat tightness or constriction
Skin and subcutaneous tissue disorders:
Severe skin reactions including Erythema Multiforme, Stevens-Johnson syndrome and Toxic epidermal necrolysis
Psychiatric and nervous system disorders:
Convulsions and psychiatric events such as depressed level of consciousness, abnormal behaviour, hallucinations and delirium have been reported during Relenza administration in patients with influenza. The symptoms were mainly reported in children and adolescents. Convulsions and psychiatric symptoms have also been reported in patients with influenza not taking Relenza.
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
The clinical signs and symptoms reported with overdoses of inhaled zanamivir are similar to those reported with therapeutic doses of inhaled zanamivir and/or the underlying disease.
As zanamivir has a low molecular weight, low protein binding, and small volume of distribution, it is expected to be removed by haemodialysis. Further management should be as clinically indicated or as recommended by the national poisons centre.
Pharmacotherapeutic group: Antiviral, neuraminidase inhibitor
ATC code J05AH01
Mechanism of action
Zanamivir is a selective inhibitor of neuraminidase, the influenza virus surface enzyme. Neuraminidase inhibition occurred in vitro at very low zanamivir concentrations (50% inhibition at 0.64nM – 7.9nM against influenza A and B strains). Viral neuraminidase aids the release of newly formed virus particles from infected cells, and may facilitate access of virus through mucus to epithelial cell surfaces, to allow viral infection of other cells. The inhibition of this enzyme is reflected in both in vitro and in vivo activity against influenza A and B virus replication, and encompasses all of the known neuraminidase subtypes of influenza A viruses.
The activity of zanamivir is extracellular. It reduces the propagation of both influenza A and B viruses by inhibiting the release of infectious influenza virions from the epithelial cells of the respiratory tract. Influenza viral replication occurs in the superficial epithelium of the respiratory tract. The efficacy of topical administration of zanamivir to this site has been confirmed in clinical studies.
Resistance selection during zanamivir treatment is rare. Reduced susceptibility to zanamivir is associated with mutations that result in amino acid changes in the viral neuraminidase or viral hemagglutinin or both. Neuraminidase substitutions conferring reduced susceptibility to zanamivir have emerged during treatment with zanamivir in human viruses and those with zoonotic potential: E119D, E119G, I223R, R368G, G370D, N434S (A/H1N1); N294S, T325I (A/H3N2); R150K (B); R292K (A/H7N9). The neuraminidase substitution Q136K (A/H1N1 and A/H3N2), confers high level resistance to zanamivir but is selected during adaptation to cell culture and not during treatment.
The clinical impact of reduced susceptibility in these viruses is unknown, and the effects of specific substitutions on virus susceptibility to zanamivir may be strain-dependent.
Cross Resistance
Cross resistance between zanamivir and oseltamivir or peramivir has been observed in neuraminidase inhibition assays. A number of neuraminidase amino acid substitutions that arise during oseltamivir or peramivir treatment result in reduced susceptibility to zanamivir. The clinical impact of substitutions associated with reduced susceptibility to zanamivir and other neuraminidase inhibitors is variable and may be strain-dependent.
The H275Y substitution is the most common neuraminidase resistance substitution and is associated with reduced susceptibility to peramivir and oseltamivir. This substitution has no effect on zanamivir; therefore, viruses with the H275Y substitution retain full susceptibility to zanamivir.
Clinical experience
Treatment of influenza
Relenza alleviates the symptoms of influenza and reduces their median duration by 1.5 days (range 1.0 – 2.5 days) in adults as detailed in the table below. The median time to alleviation of influenza symptoms in elderly subjects (≥65 years) and in children aged 5-6 years, was not significantly reduced. The efficacy of Relenza has been demonstrated in otherwise healthy adults when treatment is initiated within 48 hours, and in otherwise healthy children when treatment is initiated within 36 hours, after the onset of symptoms. No treatment benefit has been documented for patients with afebrile disease (< 37.8°C).
1. Six key Phase III randomised, placebo-controlled, parallel-group, multicentre treatment studies (NAIB3001, NAIA3002, NAIB3002, NAI30008, NAI30012 and NAI30009) have been conducted with zanamivir for the treatment of naturally acquired influenza A and B. Study NAI30008 recruited only patients with asthma (n=399), COPD (n=87), or asthma and COPD (n=32), study NAI30012 recruited only elderly (≥65 years) patients (n=358) and study NAI30009 (n=471) recruited paediatric patients, 5-12 years. The Intent to Treat population of these six studies comprised 2942 patients of which 1490 received 10 mg zanamivir b.i.d by oral inhalation. The primary endpoint was identical for all six Phase III studies, i.e. time to alleviation of clinically significant signs and symptoms of influenza. For all six phase III studies, alleviation was defined as no fever, i.e. temperature <37.8°C and feverishness score of 'none'('same as normal/none' in NAI30012), and headache, myalgia, cough and sore throat recorded as 'none' ('same as normal/none' in NAI30012) or 'mild' and maintained for 24 hours.
Comparison of Median Time (Days) to Alleviation of Influenza Symptoms:Influenza Positive Population
10mg inhaled twice daily
Difference in Days
(0.5, 2.5)
(0.0, 1.5)
(1.0, 4.0)
Combined analysis of NAIB3001, NAIA3002, and NAIB3002
(1.0, 2.0)
Asthma/COPD study
(0.5, 3.25)
Elderly study
(-2.0 to 3.25)
Paediatric study
(0.5, 2.0)
In the Intent to Treat (ITT) population the difference in time to alleviation of symptoms was 1.0 day (95% CI: 0.5 to 1.5) in the combined analysis of NAIB3001, NAIA3002 and NAIB3002, 1.0 day (95% CI: 0 to 2) in study NAI30008, 1.0 day (95% CI –1.0 to 3.0) in study NAI30012 and 0.5 days (95% CI: 0 to 1.5) in study NAI30009. There are limited data in high risk children.
In a combined analysis of patients with influenza B (n=163), including 79 treated with zanamivir, a 2.0 day treatment benefit was observed (95%CI: 0.50 to 3.50).
In the pooled analysis of 3 phase III studies in influenza positive, predominantly healthy adults, the incidence of complications was 152/558 (27%) in placebo recipients and 119/609 (20%) in zanamivir recipients (relative risk zanamivir:placebo 0.73; 95% CI 0.59 to 0.90, p=0.004). In study NAI30008 enrolling patients with asthma and COPD the incidence of complications was 56/153 (37%) in influenza-positive placebo recipients and 52/160 (33%) in influenza positive zanamivir recipients (relative risk zanamivir:placebo 0.89; 95% CI: 0.65 to 1.21, p=0.520). In study NAI30012 enrolling elderly patients the incidence of complications was 46/114 (40%) in influenza positive placebo recipients and 39/120 (33%) in influenza positive zanamivir recipients (relative risk zanamivir:placebo 0.80, 95% CI: 0.57 to 1.13, p=0.256). In the paediatric study NAI30009, the incidence of complications was 41/182 (23%) in influenza-positive placebo recipients and 26/164 (16%) in influenza-positive zanamivir recipients (relative risk zanamivir:placebo 0.70; 95% CI: 0.45 to 1.10, p=0.151).
In a placebo controlled study in patients with predominantly mild/moderate asthma and/or Chronic Obstructive Pulmonary Disease (COPD) there was no clinically significant difference between zanamivir and placebo in forced expiratory volume in one second (FEV1) or peak expiratory flow rate (PEFR) measured during treatment or after the end of treatment.
Prevention of influenza
The efficacy of Relenza in preventing naturally occurring influenza illness has been demonstrated in two post-exposure prophylaxis studies in households and two seasonal prophylaxis studies during community outbreaks of influenza. The primary efficacy endpoint in these studies was the incidence of symptomatic, laboratory-confirmed influenza, defined as the presence of two or more of the following symptoms: oral temperature 37.8C or feverishness, cough, headache, sore throat, and myalgia; and laboratory confirmation of influenza by culture, PCR, or seroconversion (defined as a 4-fold increase in convalescent antibody titer from baseline).
Post exposure prophylaxis
Two studies assessed post-exposure prophylaxis in household contacts of an index case. Within 1.5 days of onset of symptoms in an index case, each household (including all family members ≥ 5 years of age) was randomized to Relenza 10 mg or placebo inhaled once daily for 10 days. In the first study only, each index case was randomized to the same treatment (Relenza or placebo) as the other household members. In this study, the proportion of households with at least one new case of symptomatic influenza was reduced from 19% (32 of 168 households) with placebo to 4% (7 of 169 households) with Relenza (79% protective efficacy ; 95% CI: 57% to 89%, p<0.001). In the second study, index cases were not treated and the incidence of symptomatic influenza was reduced from 19% (46 of 242 households) with placebo to 4% (10 of 245 households) with Relenza (81% protective efficacy; 95% CI: 64% to 90%, p<0.001). Results were similar in the subgroups with influenza A or B. In these studies, which included a total of 2128 contact cases, 553 children were aged 5-11 years, of which 123 children were 5-6 years. The incidence of symptomatic laboratory confirmed influenza in the 5- to 6-year-old group (placebo vs. zanamivir) was 4/33 (12%) vs. 1/28 (4%) in the first study and 4/26 (15%) vs. 1/36 (3%) in the second study, which seems to be consistent with older age categories. However, as the studies were not powered to establish protective efficacy in individual age categories, a formal subgroup analysis has not been performed.
Seasonal Prophylaxis
Two seasonal prophylaxis studies assessed Relenza 10 mg versus placebo inhaled once daily for 28 days during community outbreaks. In the first study, which involved unvaccinated, otherwise healthy adults aged ≥ 18 years, the incidence of symptomatic influenza was reduced from 6.1% (34 of 554) with placebo to 2.0% (11 of 553) with Relenza (67% protective efficacy; 95% CI: 39% to 83%, p<0.001). The second study involved community-dwelling subjects aged ≥ 12 years at high risk of complications from influenza, where 67% of participants had received vaccine in the season of the study. High risk was defined as subjects ≥ 65 years of age and subjects with chronic disorders of the pulmonary or cardiovascular systems or with diabetes mellitus. In this study, the incidence of symptomatic influenza was reduced from 1.4% (23 of 1,685) with placebo to 0.2% (4 of 1,678) with Relenza (83% protective efficacy; 95% CI: 56% to 93%, p<0.001).
Due to limited and inconclusive data, the efficacy of Relenza in the prevention of influenza in the nursing home setting has not been established.
Absorption: Pharmacokinetic studies in humans have shown that the absolute oral bioavailability of the drug is low (mean (min, max) is 2%(1%, 5%)). Similar studies of orally inhaled zanamivir indicate that approximately 4-17% of the dose is systemically absorbed, with serum concentrations generally peaking within 1-2 hours. The poor absorption of the drug results in low systemic concentrations and therefore there is no significant systemic exposure to zanamivir after oral inhalation. There is no evidence of modification in the kinetics after repeated dosing with oral inhaled administration.
Distribution: Zanamivir is not protein bound (<10%). The volume of distribution of zanamivir in adults is approximately 16 L, which approximates to the volume of extracellular water. After oral inhalation, zanamivir is widely deposited at high concentrations throughout the respiratory tract, thus delivering the drug to the site of influenza infection.
Biotransformation: Zanamivir has been shown to be renally excreted as unchanged drug, and does not undergo metabolism.
Elimination: The serum half-life of zanamivir following administration by oral inhalation ranges from 2.6 to 5.05 hours. It is eliminated entirely through renal filtration. Total clearance ranges from 2.5 to 10.9 L/h as approximated by urinary clearance. Renal elimination is completed within 24 hours.
Patients with renal impairment: Inhaled zanamivir results in approximately 4-17% of the inhaled dose being absorbed. In the severe renal impairment group from the single IV zanamivir dose trial subjects were sampled after a dose of 2 mg or twice to four times the expected exposure from inhalation. Using the normal dosing regimen (10 mg bid), the predicted exposure at Day 5 is 40-fold lower than what was tolerated in healthy subjects after repeated iv administration. Given the importance of local concentrations, the low systemic exposure, and the previous tolerance of much higher exposures no dose adjustment is advised.
Patients with hepatic impairment: Zanamivir is not metabolised, therefore dose adjustment in patients with hepatic impairment is not required.
Older patients: At the therapeutic daily dose of 20mg, bioavailability is low (4-17%), and as a result there is no significant systemic exposure of patients to zanamivir. Any alteration of pharmacokinetics that may occur with age is unlikely to be of clinical consequence and no dose modification is recommended.
Paediatric patients: In an open-label single-dose study the pharmacokinetics of zanamivir was evaluated in 16 paediatric subjects, aged 6 to12 years, using dry powder (10 mg) inhalation formulation (Diskhaler device). The systemic exposure was similar to 10 mg of inhaled powder in adults, but the variability was large in all age groups and more pronounced in the youngest children. Five patients were excluded due to undetectable serum concentrations at all time points or 1.5 hours post-dose, suggesting inadequate drug delivery.
General toxicity studies did not indicate any significant toxicity of zanamivir. Zanamivir was not genotoxic and no clinically relevant findings were observed in long term carcinogenicity studies in rats and mice.
No drug-related malformations, maternal toxicity or embryotoxicity were observed in pregnant rats or rabbits or their foetuses following intravenous administration of zanamivir at doses up to 90 mg/kg/day. Following subcutaneous administration of zanamivir in an additional rat embryofoetal development study, there was an increase in the incidence rates of a variety of minor skeletal and visceral alterations and variants in the exposed offspring at the highest dose 80 mg/kg, three times daily (240 mg/kg/day; total daily dose), most of which remained within the background rates of the historical occurrence in the strain studied. Based on AUC measurements, the 80 mg/kg dose (240 mg/kg/day) produced an exposure approximately 1000 times the human exposure at the clinical inhaled dose. In the peri- and post-natal developmental study conducted in rats, there was no clinically meaningful impairment of development of offspring.
Intravenous doses of up to 90mg/kg/day zanamivir produced no effect on fertility and reproductive function of the treated or subsequent generation in male and female rats.
Lactose monohydrate (which contains milk protein).
Not applicable
10 years
Do not store above 30°C.
Relenza inhalation powder is packed in a circular aluminium foil disk (a Rotadisk) with four regularly distributed blisters. An inspiration driven inhaler made of plastic (a Diskhaler) is used for administration of doses (the contents of 2 blisters constitute a dose) from these foil disks, and is provided in the pack.
The pack contains 1 or 5 foil disks and a Diskhaler.
The inhaler (Diskhaler) is loaded with a disk containing inhalation powder packed in individual blisters. These blisters are pierced when the inhaler is used, and with a deep inhalation the powder can then be inhaled through the mouthpiece down into the respiratory tract. Detailed instructions for use are enclosed in the pack.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Glaxo Wellcome UK Ltd trading as GlaxoSmithKline UK
GSK Medicines Research Centre
Gunnels Wood Road
Date of first authorisation: 24 June 1999
Date of last renewal: 02 October 2008
19 September 2023


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Book Description from Back CoverCarrying a photograph of the man she is to marry but has yet to meet, young Hana Omiya arrives in San Francisco, California, in 1 91 7, one of several hundred Japanese "picture brides" whose arranged marriages brought them to America in the early I 900s.
Her story is intertwined with others: her husband, Taro Takeda, an Oakland shopkeeper; Kiku and her husband Henry, who reject demeaning city work to become farmers; Dr. Kaneda, a respected community leader who is destroyed by the adopted land he loves. All are caught up in the cruel turmoil of World War II, when West Coast Japanese Americans are uprooted from their homes and imprisoned in desert detention camps. Although tragedy strikes each of them, the same spirit and strength that brought her to America enable Hana to survive.
Comments from Back Cover"Yoshiko Uchida is the foremost Japanese American woman writer of our time. Picture Bride is a tender, painful, exquisitely written novel... a very serious and important book."
-Barry Gifford
"A moving tribute.... A rare insight into the hearts and minds of Japanese immigrant women and the important role they played in the establishment and survival of ethnic family and community life in America. "
"With insight, pathos, and deep understanding, the author, in her graceful, dignified way, dares to expose Hana as a long-suffering, independent, assertive woman who is frustrated and stifled as she struggles to adjust to a hostile culture that is blind to her sense of values.
Background on Yoshiko UchidaYoshiko Uchida was born in Alameda, California, and spent most of her life in Berkeley. The author of more than 25 books, she chronicled her own World War II experiences in Desert Exile: The Uprooting of a Japanese-American Family
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Most recent revision July 11, 2008