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ISO New England maintains an ongoing 10-year plan for the region to ensure the power grid will continue to meet New England's evolving needs. The plan is built on a foundation of standards and criteria for reliability set by the ISO, Northeast Power Coordinating Council, and North American Electric Reliability Corporation. The plan is refined and finalized through an open and collaborative process with the region's stakeholders, including generator and transmission-owning entities, as well as state representatives. Careful studies and analyses inform the plan and are also used to evaluate proposed projects initiated in response to the plan or market signals.
The Regional System Plan (RSP) is a comprehensive planning report on system needs and the resource and transmission facilities needed to maintain the reliable operation of New England's power system over a 10-year horizon. The RSP also accounts for market efficiencies in addition to economic and environmental considerations
The CELT Report is ISO's annual 10-year forecast of capacity, energy, loads, and transmission—a source for planning and reliability study assumptions
In accordance with Attachment K, Section 4.1(b) of the ISO's Open-Access Transmission Tariff (OATT), the ISO performs Economic Study analyses to inform stakeholders about different future systems
The Future Grid Initiative is a key project to assess the prospective needs of the regional power system in light of state energy and environmental laws; exploring potential pathways forward to ensuring a reliable, efficient, and sustainable clean-energy grid
Environmental and Emissions reports provide the ISO's annual assessments of air emissions from regional electricity generators


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Address: 261 Mulgoa Road, Penrith NSW 2750
Book Direct with the Owner at Quality Inn Penrith in Penrith with Accommodation Bookings. Click on the Email or Call Now button to get your special price, talk with the owner to get a special price.
We are a near new 60 room 4 star property situated at the foot of the Blue Mountains about 500 mts off the M4 motorway. Our rooms feature well lit work desks, data modem ports, electronic in room safes large enough for a laptop computer, coffee, tea and ironing facilities, hair dryers. Free Foxtel to all rooms.Quality Inn Penrith shares the site with the Grey Gums Hotel which offers a fantastic bistro (room service avaiable), casino lounge, sports bar and lounge bar, TAB and bottle shop. Also on the property is Chili's and Hungry Jacks then across the road we have Red Rooster, Pizza Hut, Subway and Vaby's Restaurant. Over the road is the Oxigen mind & body fitness centre including Day Spa. We are 10 minutes to the Olympic White Water Rafting and International Regatta Centre, the Museum of Fire. Also Eastern Creek and Oran Park raceways are 25 minutes and Katoomba (Three Sisters etc.) is 45 minutes. We are also close to Nepean Hospital, several golf courses and University of Western Sydney.
Accommodation Bookings welcomes Quality Inn Penrith, the ideal Penrith NSW Holiday outlet for all the family to enjoy. We have made sure that we have thought of everything you would expect from your vacation with many features, click on the email or phone now button to get in touch with the owner.Is Quality Inn Penrith in Penrith your property on Accommodation Bookings, please claim your listing and subscribe to update your contact details and receive your phone calls and emails from your clients.

subset: commoncrawl


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-Thomas Merton
A Facebook friend posted this quote on her "Wall". Yesterday, while I was taking my morning Zen walk, I saw this friend coming into my building. We quickly got into a very engaging conversation about Merton, the Dalai Lama, Buddhism, and spirituality in general. Thomas Merton has been one of the most influential people in my life. He was a Christian monk and he lived in the same monastery that I lived in although we were not there at the same time. Although a Christian monk he is the person who introduced me to Zen and Buddhist thinking. Shortly before his death in 1968 he met with a then young Dalai Lama in India. Today the Dalai Lama thinks Merton was the bridge between Eastern and Western spirituality. Before leaving for Asia to meet with various spiritual leaders, Merton spent the last three years of his life living as a hermit on the monastery grounds. He had a small house in the woods away from the main monastery. I have been fortunate to make two retreats, completely alone, in Merton's Hermitage. To live and sleep in the very space where one of my biggest influences lived was very meaningful to me.


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To coincide with Open Eye Gallery's current exhibition Breaking the Code of Silence, Redeye brings you a talk by Michael MacKenzie on his project Valley of Light. Michael will discuss this unfinished body of work, which explores his Italian mother's life in a small village in Southern Italy, Valleluce.
Through the use of landscape and still life photography Michael Mackenzie has documented the places and spaces his mother would regularly frequent in her daily life during her educational, domestic, social, religious and leisure times. The work is a personal journey to give Michael a better understanding of his mother's life and surroundings when she was growing up and how these shaped her life before she came over to England in the 1950s.
This ongoing work also explores the migration of other Italians from Southern Italy to the North West of England and in particular Michael's continuing work with the Italian community in Ancoats (Little Italy), Manchester.


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Penske to Attend Milicruit Online Career Fair
Penske will participate in a Milicruit online career fair on Nov. 13, from 1 p.m. to 4 p.m. ET.Milicruit is a website devoted to pairing U.S. military veterans with prospective employers. This event is open to both military veterans and military spouses. Visit http://www.veteranscareerfair.com/to register.
Penske's human resources staff will host real-time chats with prospective associates, seeking to hire for U.S. jobs like: technicians/mechanics, vehicle maintenance supervisors/managers, drivers, sales and customer service.
Penske is on the current G.I. Jobs magazine Top 100 Military-Friendly Employers® list.
For additional information visit Penske's careers page or follow the company on Twitter, @GoPenskeCareers. The company offers competitive wages and a wide range of benefits. Penske is an Equal Opportunity Employer.
By "Move Ahead" Staff


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New product
Exclusive table of cheeses of three milks. A delight for lovers of cheeses. Port Gamoneu, blue Pria three milk, and Picon Bejes - Tresviso.
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Platter of three milks cheese
Exclusive table of cheeses of three milks. A delight for lovers of cheeses. Port Gamoneu, blue Pria three milk, and Picon Bejes - Tresviso.
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A combination that will delight the cheese maker. With exclusive and hard to find products. All of them are produced with three types of milk: cow, goat and sheep. This includes the exclusive Gamoneu Port, blue Pria three milk and the spicy and strong Picon of Bejes - Tresviso.
Picón Bejes-Tresviso artisan cheese, is a blue cheese made with cow's milk, milk from sheep and from goats that have been grass-fed. The cheese is left to mature for 2 months in natural caves with high humidity in the region of Liébana (Cantabria). It is an intense, slightly acidic and spicy tasting cheese that is a little firm, almost soft, since it is...
The Gamoneu del Puerto or the Gamonedo del Puerto is one of the most exclusive cheeses made in Spain. It is made in the Western Massif mountains of the European peaks in Onis and Cangas de Onis, in shepherds' cabins who produce it there along with the milk of their own livestock, and it is aged in caves also located in the mountains. Today there are only...
Delicious blue cheese made from cow's milk to which sheep's milk cream and goat's milk cream are added. A traditional but surprising three-milk cheese that is lightly smoked and has the presence of penicillium mold. You can buy it in the next LINK


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Friday, November 09, 2012
Crowdfunding Journey: Patience Is A Virtue
This week is all about not forgetting the details and creating a calm and relaxing place and most importantly, having patience!
While it is very easy to say "be patient," it is quite another to actually be it…. especially when you're ready to launch a crowdfunding campaign.
Right now I am going over campaign materials with a fine tooth comb. I am dealing with technical issues as this is happening! Yikes.
I am more than ready in my mind to launch but must, must make sure that everything is truly in place and checked off for a successful launch.
Hint: Make sure you have step by step donating instructions in your copy for all those recipients that have never given to a crowdfunding campaign.
Patience is my meditation!
Start breathing deeply.
Thank you all again for your amazing support, I appreciate it more than you can ever image! Please visit the link below to watch as I discuss what has been happening this week with my crowdfunding journey.
Looking forward to your feedback and speaking with you again soon!
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Robert Moyes
Monday Magazine columnist
It's been 25 years since Steven Spielberg first invited audiences to marvel – and then scream, again and again – at dinosaurs brought back to life via genetic manipulation.
That popcorn classic has been clumsily cloned a few times since – but with over $4 billion to show for it, who can blame them? A decent reboot of the series landed in the theatres in 2015 and now we have Jurassic World: Fallen Kingdom to entertain us with a thrill-a-minute reminder that messing with prehistoric über-predators is always a bad idea.
In the original World, a Disneyfied theme park for dinosaurs came to a spectacularly gory end; in Kingdom we learn that the abandoned island, still inhabited by dozens of dinosaur species, is being torn apart by extreme volcanic activity.
Enter the deeply concerned Claire Dearing (Bryce Dallas Howard), who played a corporate loyalist in the earlier film but has reinvented herself as a "dinosaur rights" activist desperately hoping to save at least some of the toothy critters from destruction. But the last minute, military-scale rescue evacuation that gets put together has a sinister agenda lurking beneath its benign façade, and Claire and returning velociraptor-wrangler Owen Grady (Chris Pratt) spend the rest of the movie struggling to outwit a large number of human and reptilian opponents.
There are lots of technically impressive set pieces, although they tend to evoke memories of the Jurassic original rather than showing much fresh imagination.
That said, it's always satisfying when vile scoundrels scream their last as massive dino jaws start chomping away, and director J.A. Bayona dispatches key villains with gory gusto. (Hey, greedy fools, we told you not to mess with Mother Nature!) There are some good comedic touches too, especially involving a thickheaded dinosaur that butts like a billy goat.
Although many critics have harrumphed that Kingdom seems to have emerged from the Cretinaceous Period, this is perfectly adequate escapist fare.
Pratt has a sturdy, utilitarian charisma, Howard has become more than just a pretty face and the action-heavy plot – although often predictable – chugs along efficiently. And even if the scenes with the delightfully weird Jeff Goldblum testifying to Congress fall flat, Toby Jones picks up the slack as the sinister and deliciously slimy businessman with a wild scheme to profit from all those dinosaur refugees.
Rating: **1/2
Stars: Chris Pratt, Bryce Dallas Howard; Director: J.A. Bayona
Playing now at the Cineplex Odeon, SilverCity Victoria and Landmark Cinemas 4 University Heights.
–– Don't Worry, He Won't Get Far on Foot
Soulful director Gus Van Sant should deliver the goods in this true-life drama about famed cartoonist John Callahan (Joaquin Phoenix) who only discovers his talent after a drunk-driving accident leaves him a quadriplegic. With Jonah Hill, Rooney Mara, and Jack Black.
–– Equalizer 2
Denzel Washington reunites with hard-edged action stylist Antoine Fuqua (Training Day) to repeat his role as a former CIA operative who goes from benign to brutal when circumstances demand a vigilante hero.
–– Mamma Mia: Here We Go Again!
Meryl Streep, Amanda Seyfried, Pierce Brosnan, Colin Firth, Stellan Skarsgard – and a new-to-the-party Cher! –sing up a storm in this ABBA-tastic musical comedy sequel.
–– Mission: Impossible – Fallout
Expect twisty plotting and ferociously adrenalized stunts as Ethan Hunt (Tom Cruise) and his crew of spy guys race against time to prevent a global catastrophe. With Henry Cavill, Simon Pegg, Ving Rhames and Rebecca Ferguson.
–– Skyscraper
As if Jumanji wasn't enough excitement for 2018, amiable action-meister Dwayne Johnson plays a former FBI agent who has to save his family from a blazing fire in the world's tallest building.


text: Last night I crossed of Mill City Nights and seeing Nikki Sixx from my bucket list! 93X Live Nation hosted the Vamps, Apocalyptica (um, wow) and Sixx Am (think, Heroin Diaries, Vegas style). If you take New Age Hair Metal, sprinkle in a little Heavy Rock, add some Steven Tyler Dance moves, throw in some incredibly talented musicians and play up the already amazing stage presence, you will get the Modern Vintage Tour. So good.


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The Holy Family fled to Egypt because Saint Joseph had been warned in a dream that Herod wanted to kill the Christ Child. New Testament (Matthew 2: 13-15). Here, they are shown resting on the journey, close to a waterfall. The rest on the flight is not described in the Bible, yet it was a very popular subject in European painting. The apple Joseph is holding refers to the original sin of Adam and Eve, from which Christ, as the new saviour, will redeem mankind. Lastman was the leading painter of biblical and mythological subjects in Amsterdam in the early 17th century and the teacher of Rembrandt and Jan Lievens. In this important dated work the landscape is more extensive than is usual in his biblical scenes: it displays his study of the landscapes of Adam Elsheimer (1578 - 1610) and his contemporary Jacob Pynas (born about 1585; died after 1648), whose works are represented in the National Gallery's Collection.
The National Gallery has endeavoured to make as many images of the collection as possible available for non-commercial use. However, an image of this painting is not available to download. This may be due to third party copyright restrictions.
If you require a license for commercial use of this image, please use the National Gallery Company's Online Picture Library or contact them using the following:


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Found 42 collections related to Rodgers, Richard, 1902-1979
Page 1 of 2
Rodgers, Richard, 1902-1979
Music Division | JPB 13-30
3.54 linear feet (10 boxes)
Richard Rodgers (1902-1979) was an American composer and producer, well known for his collaborations with lyricists Lorenz Hart and Oscar Hammerstein II. The Richard Rodgers music papers contain scrapbooks, published vocal scores, and drafts of... more
Mielziner, Jo, 1901-1976
Billy Rose Theatre Division | *T-Mss 1993-002
Jo Mielziner, set and lighting designer, theater architect and consultant. The collection consists of personal papers, personal and professional correspondence, production materials, office and financial files, writings, professional appearance... more
Bay, Howard
Billy Rose Theatre Division | *T-Vim 1986-007
53 linear feet (43 flat boxes)
Howard Bay, set and lighting designer, theater architect, teacher and consultant. The collection consists of set and costume designs, technical drawings, elevations and whiteprints documenting the work of Howard Bay.
Rodgers, Richard, 1902-1979
Billy Rose Theatre Division | *T-Mss 1987-006
The Richard Rodgers Papers consist of correspondence, photographs, posters, newspaper clippings, and other material related to the career of Richard Rodgers. There is a small series of production files which includes materials on THE KING AND I,... more
Wilson, Robert A. (Robert Alfred), 1922-2016
Billy Rose Theatre Division | *T-Vim 1985-004
Robert A. Wilson, proprietor of the Phoenix Bookshop (New York, N.Y.). Color slides of Broadway and Off-Broadway productions.
Found in
Hayward, Leland, 1902-1971
Billy Rose Theatre Division | *T-Mss 1971-002
179 linear feet (332 boxes)
The Leland Hayward Papers reflect the activities of Hayward's business office during his active years as a theatrical, motion picture and television producer. The majority of the collection relates to the various works Hayward produced in those... more
Burns, Ethel
Music Division | LPA Mss 2011-001
10.29 linear feet (25 boxes)
The Ethel Burns papers document the music, arts and children's programs Burns produced and directed at radio/television station WNYE and television station WCBS in New York City. The files include scripts, correspondence, production information,... more
Struble, Helen Gates
Billy Rose Theatre Division | *T-Mss 1995-031
Helen Gates Struble was an actress who began her career as a Ziegfeld girl. The collection contains ephemera from her career in the theater.
Van Druten, John, 1901-1957
Billy Rose Theatre Division | *T-Mss 1958-002
The John Van Druten papers consist of diaries, correspondence, writings, scrapbooks and ephemera documenting his life and career. The papers span the years 1901-1957 and give excellent insight into Van Druten's creative processes. Missing from the... more
Abarbanell, Lina, 1880-1963
Billy Rose Theatre Division | *T-Mss 1963-001
.8 linear feet
The Lina Abarbanell Papers consist of production files, correspondence, manuscripts and outlines of plays and other writings of her husband, Edward Goldbeck and her daughter, Eva. The papers span the years 1886 to 1963. However, the materials are... more
Rodgers, Richard, 1902-1979
Music Division | JPB 82-75 no. 6
1 ms. score (47 items in 4 boxes), 53 x 43 x 8 cm; 1 ms. score (47 items in 4 boxes), 53 x 43 x 8 cm
Lewine, Richard
Billy Rose Theatre Division | *T-Mss 2006-008
35.5 linear feet (42 boxes, 1 tube)
Richard Lewine was a musical theater composer, an author of works of scholarship on musical theater and a theater and television producer, working mainly from the 1930s through the 1980s. This collection includes personal files, scores, scripts,... more
Ager, Milton, 1893-1979
Mrs. Astor's pet horse / Milton Ager and Richard Rodgers ; orchestrations principally by J. Toliver, Charles L. Cooke, 1942
Music Division | JPB 82-75 no. 8
1 ms. score (12 items in 1 box), 53 x 43 x 8 cm; 1 ms. score (12 items in 1 box), 53 x 43 x 8 cm
Donehue, Vincent J., -1966
Billy Rose Theatre Division | *T-MSS 1967-002
Donehue was a director working primarily for the New York stage and television in the 1950s and 1960s. He also directed two films in Hollywood. The collection includes personal correspondence; production files containing notes, letters, partial... more
Schuman, William, 1910-1992
Music Division | JPB 87-33
50 linear feet (195 boxes)
Correspondence; memoranda; reports; minutes of meetings; press releases; drafts and final copies of articles, speeches, and statements; awards and certificates; diaries; photographs; magazines; clippings; pamphlets and papers; programs; posters;... more
Blaine, Vivian, 1921-1995
Billy Rose Theatre Division | *T-Mss 1996-053
14 linear feet (18 boxes)
Vivian Blaine was a singer in concerts and nightclubs and an actress in film, television and theater from the late 1930s through the mid 1980s. She is best remembered for having originated the role of Miss Adelaide in Guys and... more
Morehouse, Ward, 1898-1966
Billy Rose Theatre Division | *T-Mss 1971-001
Ward Morehouse, journalist and playwright. The papers include correspondence, interviews, writings articles and ephemera documenting his career in the theater world.
Wiman, Dwight Deere, 1895-1951
Billy Rose Theatre Division | *ZC-310
37 reels of microfilm (35mm)
Theatrical producer, Dwight Deere Wiman produced 56 plays and musicals in 26 years on Broadway making his most distinctive imprint in the musical comedy and revue fields. He was born on August 8, 1895 in Moline, IL, a direct descendant of John... more
Oppenheimer, George
Billy Rose Theatre Division | 8MWEZ/25001-011
3 linear feet (4 boxes, 7 scrapbooks)
The George Oppenheimer papers consist of correspondence, clippings, writings, research notes and annotated playbills from his professional career as a writer and drama critic. The papers span the years 1943-1977, though there is not much from his... more
Bottari, Michael
Billy Rose Theatre Division | *T-Vim 1996-037
.1 linear feet. (1 portfolio)
Costume designers, Michael Bottari and Ronald Case. Collection consists of ten color laser prints of costume designs for the 1995 revival of the Rodgers and Hammerstein musical State Fair.
Mok, Michel, 1889?-1961
Manuscripts and Archives Division | MssCol 2029
1.3 linear feet (2 boxes)
Michel Mok (1889?-1961) was a theatrical press agent and journalist. Born in the Netherlands, he immigrated to Canada and later to the U.S. where he worked as a reporter for the New York Post. In the mid-1940s he associated himself with Richard... more
Dolbin, Benedikt F.
Music Division | JOB 84-4
1 linear foot (2 boxes)
Benedikt Fred Dolbin (1883-1971) was a graphic artist from Vienna, Austria who emigrated to New York City during the Nazi era of the 1930s. While in Austria, he had studied music composition with Arnold Schoenberg. He specialized in caricatures of... more
Lillie, Beatrice, 1894-1989
Billy Rose Theatre Division | *T-Mss 2000-012
37.8 linear feet (75 boxes)
Beatrice Lillie, comedienne, actress, singer and author, was born May 29, 1894 in Toronto, Ontario, Canada. The Beatrice Lillie papers consist of 37.8 linear feet spanning the 1910s to the 1990s. The collection consists of correspondence,... more
Mielziner, Jo, 1901-1976
Billy Rose Theatre Division | *T-Vim 1993-002
Jo Mielziner, set and lighting designer, theater architect and consultant. The collection consists of set and costume designs, technical drawings, elevations and whiteprints documenting the work of Jo Mielziner.
New Amsterdam Theatre Company
Rodgers and Hammerstein Archives of Recorded Sound | *LTC 1242-1251
10 sound cassettes : analog, 1 7/8 ips Dolby B processed
Recordings of five musical theatre revivals at the Town Hall concert hall in New York (N.Y.) in 1985 and 1986. Included are recordings of: Jerome Kern's Music in the air, Sweet Adeline, and Leave it to Jane; Richard Rodgers' I married an angel;... more
Rodgers, Richard, 1902-1979
Music Division | JPH 85-5
60 v : ill, music ; 44 cm
The Richard Rodgers scrapbooks contain materials collected by Richard Rodgers, generally pertaining to his shows and other professional activities.
Rodgers, Richard, 1902-1979
Rodgers and Hammerstein Archives of Recorded Sound | *L (Special) 89-19
362 sound recordings : analog
The collection contains commercial discs and noncommercial recordings; the latter containing interviews with Rodgers and his family and friends, performances of his music by contemporary performers, as well as radio and television programs that... more
Ryskind, Morrie, 1895-1985
Billy Rose Theatre Division | *T-Mss 1996-024
Morrie Ryskind, poet, playwright, and columnist. Awarded the 1932 Pultizer Prize for drama for Of Thee I Sing co-written with George Kaufman, Ira Gershwin, and George Gershwin. Testified before the House Un-American... more
Stewart, Michael, 1929-1987
Billy Rose Theatre Division | *T-Mss 1990-018
Michael Stewart (nee Rubin), librettist, lyricist, playwright, and novelist, was born in New York City, where he attended Queens College. He received a Master of Fine Arts in drama from Yale in 1953. Prior to his work on Broadway, Stewart wrote... more
Brent, Romney, 1902-1976
Billy Rose Theatre Division | *T-Mss 1998-011
The Romney Brent papers document his career and contain correspondence, photographs and two scrapbooks. The collection is incomplete in that it contains only correspondence from his later years and photographs and scrapbooks from his early career.... more
Page 1 of 2
Indicates that portions of this collection have been
digitized and are available online.
digitized and are available online.


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The Camp Kit was featured on ABC's FABLife! A few weeks ago we went down to LA to deliver a Camp Kit to ABC Studios. We had such a fun time hanging out with the...Read More


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Maastricht University is expanding its range of programmes with the addition of a bachelor's degree in Brain Science. The course will start in September 2024 and is open for enrolment from today.
At the CARIM research institute (school for cardiovascular diseases) in Maastricht, a group of researchers – led by Joost Lumens - is working with 'het digitale tweelinghart' (the digital twin heart): a computer model that simulates the human heart. This research gives rise to a great deal of...
Christian Ernsten and Claartje Rasterhoff, in collaboration with Natuurmonumenten, receive €100,000 for their project 'Rivier Atelier at the Geuldal: heritage management in times of climate change'.
In light of the fast developments within the use of generative AI, the SHE Management Team has developed guidelines for the use of AI.
Marieke Dewitte is one of the scientists performing at the Maastricht Theater aan het Vrijthof on Tuesday, Oct. 10, during the theatre tour of the University of the Netherlands.
In this inaugural lecture, Lars van Vliet addressed the question of how legal proceedings surrounding Nazi looted art should be shaped in a balanced way to ensure a fair trial.
Lee Bouwman, a vascular surgeon, works as a researcher on the implementation of new techniques in healthcare. As professor by special appointment of Clinical Engineering at the Faculty of Science and Engineering (FSE) and the Zuyderland Medical Centre, he seeks collaboration between engineers and...
The EU-funded project FullCompensation aims to make the compensation of pain and suffering damages more equitable and efficient. To this end, the project led to the development of a model legislative proposal and guidelines, based on comparative and empirical evidence. These documents are intended...
"Wie als slachtoffer zijn recht zoekt, verdwaalt gemakkelijk in juristerij en een wereld waarin veel onbestraft blijft", aldus Steven van de Put, promovendus aan de universiteit Maastricht. "Dit moet én kan anders. Het kan niet zo zijn dat individuen of groepen van individuen die iets ergs is...


text:
I'd have to refuse, too."
In order to catch Rowaine, Herman had to pester her in various ways because it was not enough for him to engulf her with the sweet talk.
Still, it was not in vain as he managed to succeed in holding her.
'Still, that look… it isn't my expectation.'
Smiling to himself, he shook his head slightly.
He could not believe he was rejected by Rowaine.
After all, she was always the one who was insisting on him to go play with him first because she was always bored.
As he thought so, Herman glanced at Rowaine, who was standing in front of a large window in the drawing room with languid eyes.
He could not smell her perfume, which usually stung his nose whenever he saw her, like usual, and that somehow made her feel even more unfamiliar.
'She's different.'
Rowaine was such a fickle person, so he thought that she was just pretending to be changed because of some tide this time because she liked to show him a new side — one day, she would act like a shy girl, and another day, she would act like a bewitching woman.
Even after, she would act like a virtuous lady.
…So, what is it this time What was her plan of going to Blois Had she gotten tired of playing around with the Emperor
Although Herman was curious, he did not care much since he thought Rowaine would soon get bored and come back to beg him to play with her.
However, that was a mistake… It was because this time, Rowaine has not shown her face to him for quite some time.
'What could it be'
As he was lost in his thoughts about Rowaine, the wine glass in his hand quivered a little.
The blood-colored liquid was very fragrant though Herman's mind was all directed at the person in front of him.
She was the one who liked his smiling face.
But now, no matter how determined and smiling he was, it was difficult to attract Rowaine's attention.
Somehow, he did not like it.
It felt like he was looking for something that you normally don't even know existed when you have already lost it.
Watching her, who kept staring out the window, made his nerves a little sensitive.
Erman whispered softly, hiding his sharp feelings behind his smile.
"You've changed, Duchess—like someone else wearing Rowaine's shell."
"Because I'm married."
Rowaine had an awkward expression stained on her face.
Even that expression was unfamiliar to Herman.
It was the first time he knew she could make that kind of look….
Or, perhaps, it was because she was using honorifics Even the way she spoke was unfamiliar.
"People change when they find true love, don't they"
Herman's eyes narrowed.
At that moment, Duke Blois entered the drawing room.
'He must've come here after hearing that she was alone with me like a demon*.'
[ T/N: Here, it meant specifically, 'In a manner of being amazingly precise and accurate in action or guess.' ]
Rowiane rejoiced to see the Duke of Blois, who was staring at Herman with pleased eyes, emitting wariness against him as if protecting a treasure in front of him that no one was allowed to touch.
Was he not like a stranger to Rowaine The Duke of Blois would not even know her true self.
When Rowaine reached out her hand, Duke of Bloise wrapped his hand around her waist as if he had been waiting.
Even though she seemed a little surprised at first, she soon gazed up at Duke of Blois with a face like she was falling in love.
As though he was concerned, the Duke whispered to her ears softly the next moment.
"Didn't you say you weren't feeling well"
"It's better to rest early because you're ill."
"Oh, right.
I did.
That'd be nice."
Herman laughed to himself.
'Is that what you call acting now'
He knew that Rowaine would try to provoke his jealousy by flirting with the Emperor.
At the time, he did not think much of it… but why was his stomach feeling so twisted now
With an unpleasant feeling crept into him, he suddenly opened his mouth and spoke of Rowaine's preference that he knew.
"The Duchess, Rowaine, has always loved stormy days.
I guess the Duke doesn't seem to know that yet."
At his arrogant tone, the Duke of Blois narrowed his brow.
"You say you've been friends for a long time though you don't know much about my wife, do you She doesn't like days like this."
"Is that possible On days like this, we would all gather together and enjoy scary stories until late at night.
If you listen to the story I've prepared, you'll forget about being sick and enjoy it."
Saying so, Herman reached out his hand towards Rowiane.
'Hold it, Rowaine.
As you always do.'
Even when she was playing around with the Emperor, she never wavered at his outstretched hand.
Because of that, he was confident.
"I'm sorry.
But, I'm tired today, so I need to rest early."
…He was rejected.
This time, it was a real refusal that would not work, even if he pestered or squeezed her.
Herman stared blankly at the back of Rowaine, who was leaving the drawing room with the Duke of Blois.
At the same time, his mask, which had been smiling tenderly the whole time, was crumpled.
'…Is she really Rowaine'
At this moment, he thought back to how the dog shapeshifter and Rowaine were looking at each other earlier.
゚・ : * ✧ * :・ ゚
As night fell, the wind grew stronger, and the rain streamed down like a torrential downpour.
I was in the room chatting a little bit with Agwen about the employees, and at some point, the rain got so loud that her voice was barely audible.
By the time I realized that I was speaking with a loud voice, the wind rumbled and shook the window.
Startled, I muttered quietly and glanced out the window.
At that moment, lightning flashed behind the curtains, and a loud bang was heard as if something exploded somewhere.
"The thunder is loud."
"…I know.
It wouldn't break the windows, would it"
"It's a sturdy window that survived last year's typhoon without any ambivalence, so it'll be fine.
If you're worried, should I have your servants hang up the shutters"
"Oh, my God.
Do you want to kill someone"
The wooden shutters were used to increase the thermal effect by hanging outside the window.
Because of my anxiety, I could not help but imagine people hanging from windows in this weather, trying to install the wooden shutters.
"I'm okay.
Just… can you bring me some of the lights that decorated the bathroom back then"
I thought that if I slept with a small light on, I might be less afraid.
On a thundering night like this, I was not confident if I could sleep alone in this spacious bedroom.
'It's really scary.'
However, to ask Agwen to sleep with me…
'It's a job that requires overtime pay.
How much does she want to get off work'
I wanted to keep the time off to the employees.
'I'm not young enough to cause trouble to others just because I'm afraid of thunder.'
After Agwen turned on the lights and left the room, I laid down on the bed before pulling the blanket up to my neck.
'Come to think of it, what are Coco and Sasha doing now…'
At dinner, the two of them seemed excited about playing the new card game they had learned from Liddell in the evening as if they couldn't care less about the weather.
'If Sasha came to see me because she was afraid, she would hug her and sleep with her.'
Nonetheless, it seemed like Sasha's valiant personality would not make her afraid of thunder and lightning.
At the terrifying sound of the wind, I hurriedly pulled out the blanket more and covered my face up half way.
"I'm scared…"
I mumbled without realizing it, then shook my head and alluded to myself in a slightly louder voice.
"I'm not scared! I'm not afraid of anything! Haha! It's just wind and thunder! No, I'm afraid…"
…It seemed like it was going to be a long night.
゚・ : * ✧ * :・ ゚
Before falling asleep, Dimitri, who had transformed into a cat, was lying curled up in a box while hugging the cat cushion he had taken from Rowaine previously.
No matter how much he sniffed, the cushion no longer smelled of grass from her.
As he was smacking his lips*, he could suddenly hear a voice from the secret door that connected to Rowaine's room.
[ T/N: It's an idiom which means, 'To be dissatisfied or embarrassed because something does not go as one wishes.' ]
"I'm not scared! I'm not afraid of anything! Haha! It's just wind and thunder! No, I'm afraid…"
Resting his face with a languid expression, he glanced at the door.
'She's more scared than I thought.'
He could hear the occasional murmurs of 'not scary' or 'scary' coming and going.
When the thunder rumbled, a small groan was heard, and Dimitri ran to the secret door.
However, he could not open the door and just stand in front of it.
'If I go, she'd feel burdened.'
Rather than put her to sleep, he would make her wake up completely.
'Should I bring Sasha'
As he was thinking about it, Dimitri suddenly saw his reflection in the mirror.
He then stroked his chin with his round paw.
Even though it was absolutely unacceptable—to quote Rowaine, he was now 'Blue, the cute little gray cat.' Additionally, she also did not know that Blue was Dimitri… and he wanted to fall asleep smelling Rowaine.
After telling the devil to open the door, he went out proudly and scratched the door of Rowaine's room next door with his paws.
There was a rustling sound from inside before the overly cautious footsteps got closer and closer.
As the doorknob crept open, it seemed as if he could feel the inner feelings of Rowaine, who was not sure.
When the door was opened just a little, she then peered into the thin crevice with fearful eyes.
Seeing him sitting at the door, she opened the door wide with joy.
"Blue! It was you! Oh, I thought something was coming."
Rowaine, rubbing her chest, sat down in front of Dimitri and held out her hand.
"Were you in the mansion What kind of person opened the door for you And, how did you get to the fourth floor How do you know my room Oh, did you smell me This is so amazing."
At her questions, Dimitri approached the delighted Rowaine and rubbed his body against her, lighting abruptly flashed.
Because of that, Rowaine flinched before hugging him without realizing it.
Dimitri, being embraced in her arms wide, widened his eyes.
Not only that she was not even wearing a shawl, but her nightgown was also relatively thin with a deep chest cut.
Dimitri's body stiffened as he could feel his cheek pressed against her bare chest.
"I'm sorry, Blue.
I was so surprised that I didn't even realize."
Rowaine, who quickly calmed down, put down Dimitri with a sigh.
It was a strange feeling.
Obviously, he tended to avoid physical contact with others, but what was this disappointment…
While he was distracted by his thoughts, all of a sudden, Rowaine whispered to him in a subtly voiced voice.
"Would you like to sleep with me"


text:
Editor's Note: A version of this story appeared in the January 20 edition of CNN's Royal News, a weekly dispatch bringing you the inside track on Britain's royal family. Sign up here.
Last week was all about the Duke of Sussex. This week, it's the royal family's turn.
Considering the disclosures from the vexed prince – both in his book, "Spare," and his promotional media appearances – many were curious about how the clan would handle returning to the public eye after the holidays.
When asked by US comedian Stephen Colbert last week, Prince Harry said "of course" his family, along with the British media, is actively campaigning to undermine his book. The royal added: "After 38 years, they have told their side of the story. This is the other side of the story and there's a lot in there that perhaps makes people feel uncomfortable and scared."
However, the reality is not quite as black and white. Certainly, multiple British newspapers are still running frequent follow-up headlines using sound-bites from commentators. But there appears little evidence of a coordinated effort from an army of unnamed palace sources, as Harry has asserted, to debunk his grievances. And, of course, there continues to be radio silence from the palace whenever the book is raised.
What we have seen is the Windsors throwing themselves into lots of walkabouts and meetings as they embarked on their first engagements of the year.
King Charles and the Prince and Princess of Wales kicked things off two days after "Spare" hit bookshelves. Up in Scotland, the monarch laughed heartily with members of the public while at a local community space aiming to combat rural loneliness.
The same day, William and Kate appeared at ease as they called in at the new Royal Liverpool University Hospital and the mental health charity Open Door in Merseyside, northern England. There were no signs of apparent sadness over their disgruntled relative in California and questions shouted toward the couple asking if they had been "hurt by the comments in Harry's book" went unanswered.
In the days since, senior royals have conducted engagements at schools, youth charities and other royal patronages.
The prince's tell-all has gone on to break records, with its publisher claiming Tuesday that it had sold three quarters of a million copies in the UK since its release. Larry Finlay, managing director of Transworld Penguin Random House, said: "We announced last week that SPARE was the fastest selling non-fiction book ever on its first day of publication, a record that has been confirmed by Guinness World Records. We now know that it is also the biggest selling memoir ever in its first week of publication."
That doesn't appear to have fazed the royals. They will be keenly aware of the optics following the book's publication. But rather than be dragged deeper into the soap opera by releasing statements or canceling planned events, they have focused on earning back any civic trust that may have been damaged – by getting back to work.
The royals know "the power of our platform," as Harry so succinctly put it in his memoir. They know that they need to be seen, that personally greeting the public at events they care about resonates long after they leave and that throwing the royal spotlight on local enterprises can amplify an organization's message and needs like nothing else.
Their actions this past week have served as a reminder to the public that family feuds aren't stealing their attention. It remains firmly on the British people and the challenges they face as the new year gets underway. King Charles' recent request to use some of the Crown Estate profits for "the wider public good," instead of reinforcing the royal coffers, is another example of this.
The Crown Estate announced Thursday that six new offshore wind energy lease agreements had generated a large windfall. Through an arrangement established in 1760, the monarch surrenders all profits from the estate to the UK government in return for a slice called the Sovereign Grant – which is essentially the King's expense account.
However, a Buckingham Palace spokesperson told CNN: "In view of the offshore energy windfall, The Keeper of the Privy Purse has written to the Prime Minister and Chancellor to share The King's wish that this windfall be directed for wider public good, rather than to the Sovereign Grant, through an appropriate reduction in the proportion of Crown Estate surplus that funds the Sovereign Grant."
As royal trustees of the fund, Prime Minister Rishi Sunak, Chancellor of the Exchequer Jeremy Hunt and Keeper of the Privy Purse Michael Stevens determine the actual amount of the grant. The fund is currently set at 25% of the annual net profits of the Crown Estate. That means that in the past financial year the UK Treasury paid out £86.3 million, which is used to cover official travel, staff costs and palace expenses.
The exact sum headed to the public purse from the King is not yet clear. It also won't leave him worse off this year because the amount he receives is based on the two financial years prior – so the impact of the monarch's moves won't hit the grant until 2024-2025. But it will probably be seen as a welcome symbolic gesture at a time when families across the nation are grappling with financial hardship.
King Charles has previously shown himself to be mindful of the ongoing cost-of-living crisis, having acknowledged how people in the UK may have struggled to pay their bills and "keep their families fed and warm" in his first Christmas broadcast.
And without complaining or explaining, the family have chosen their response – to lean into their value through service rather than engage in a war of words that would do them more harm than good.
In the past few years, Prince Harry and wife, Meghan, Duchess of Sussex have traded their broken relationship with the UK press system for the celebrity industrial complex of the US. This week on "The Assignment," host Audie Cornish turns to insiders from both media ecosystems to discuss how the duke and duchess are using the press to reshape their narrative. We hear from Los Angeles Times culture critic Mary McNamara and Newsweek's Chief Royal Correspondent, Jack Royston. Check out the podcast here.
Prince Harry dragged into execution spat after book admission.
The Duke of Sussex has found himself pulled into a quarrel between the UK and Iran over the execution of a British citizen, after claiming in his memoir that he killed Taliban fighters during his military career. Harry wrote in "Spare" that he killed 25 of the insurgent group's fighters in Afghanistan while serving in the British Army. His words have drawn criticism from some British security and military experts. Iran said this week that the UK is in no position to preach human rights after Harry's confession and accused Britain of turning a blind eye to this "war crime." Iran's Foreign Ministry wrote on its Twitter page Monday, "The British regime, whose royal family member, sees the killing of 25 innocent people as removal of chess pieces and has no regrets over the issue, and those who turn a blind eye to this war crime, are in no position to preach others on human rights." The tweets came after British Foreign Secretary James Cleverly warned Iran that it "will be held to account" for the execution of dual British-Iranian citizen Alireza Akbari. Akbari was hanged by Tehran on charges of espionage and corruption, according to a state-affiliated media outlet over the weekend.
Kim Kardashian buys Princess Diana pendant.
The Skims founder and reality TV star has acquired the diamond-lined Attallah Cross pendant worn on several occasions by Diana, Princess of Wales for £163,800 (about $200,000). In the last five minutes of the Royal and Noble collection sale at Sotheby's auction house in London on Wednesday, a representative for Kardashian successfully outbid others vying for the amethyst cross. The item sold for more than double its pre-auction estimate, Sotheby's said. Made by court jewelers Garrard in 1920, according to the auction house, the pendant features square-cut amethyst stones in the shape of a cross, decorated with circular-cut diamonds in a distinctive flowery design. It was bought from Garrard in the 1980s by the late businessman Naim Attallah, who lent the item to his friend, Princess Diana, several times to wear to events, according to Sotheby's. Read more on this story here.
A local council has been slammed for wasting money on a mural in Northampton, England depicting the late Queen Elizabeth II and King Charles III, with critics saying the street art bears little resemblance to the monarchs. The mural was commissioned by the town council to mark Charles' accession to the crown.
The Duke and Duchess of Sussex this week dismissed the latest apology from TV host Jeremy Clarkson for penning a widely condemned article about Meghan in Britain's Sun newspaper last month. The pair said it fails to address "his long standing pattern of writing articles that spread hate rhetoric, dangerous conspiracy theories, and misogyny," according to a spokesperson for the couple.
"Unless each of his other pieces were also written 'in a hurry', as he states, it is clear that this is not an isolated incident shared in haste, but rather a series of articles shared in hate," the statement released Monday continued.
The Sussexes also rejected Clarkson's claim that a letter he sent on Christmas Day to apologize for the article – in which he expressed his hatred for the duchess and wrote about wanting to see a naked Meghan being pelted with excrement – was addressed to both the duke and duchess. According to the couple's spokesperson, it was sent "solely to Prince Harry, The Duke of Sussex." The letter was marked "Private and Confidential," the statement added.
Clarkson previously apologized publicly shortly after the publication of the column, as did the newspaper, which also removed it from its website.
The King's wife this week visited the new Science Teaching Hub at the University of Aberdeen, where she has been Chancellor for the past decade and in 2020 was conferred with an honorary degree.
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text:
Wife reveals hidden herbal solution that completely treats heavy growth of staph aureus, flushes out syphilis, gonorrhea, STD infections (Sponsored)
3 years ago, I was diagnosed of having heavy growth of staph infection. Believe me, I spent close to 250,000 moving from one specialist hospital to another just looking for a cure.
But sadly, I discovered that this infection was different from anything that I have ever encountered before.
It affected my marriage, destroyed my immune system, made me infertile and also made me suffer painful symptoms.
Click Here now to see the Herbal Treatment that eliminates Staphylococcus and other infections permanently
Get it here >> http://naturehealthreach.com/staphcure
After spending so much money in hospital, we didn't give up.
My husband and I continued searching on and on, looking for a permanent solution to this menace.
The problem is, each time we visit urologist, they would recommend special expensive antibiotics for us.
After using it for some months, we would go for lab tests, the result would say scanty. Then just few months later, the symptoms come back… much heavier than before.
Some of the symptoms includes…
– itching of the private part
– painful boils
– vaginal discharge
– weakness
– wormlike movement in the body system
Truth be told, after much research, I discovered 3 things about Staph infection which I overlooked for those 3 years….
1) Staphylococcus could be stubborn especially when it gets to the stage of MRSA – Methicilin resistant Staphylococcus aureus.
So, it's becoming more resistant to high powered antibiotics.
2) Its not really an STD because one can easily be infected by using an unclean toilet or in public places from wounds, or sores.
3) Staph infection is now becoming more popular among couples in Nigeria. It's really spreading at an alarming rate and sadly antibiotics can only suppress it, but mind you it will come back heavier than before!
Fortunately for me, through the help of my mum based in UK, she discussed with a health expert friend of hers that recommended a natural herbal remedy that helps treats staphylococcus, gonorrhea, syphilis and other infections that are drug-resistant.
Here's where to get the Natural Herbal Remedy That Completely Cure Staphylococcus and other Drug Resistant Infection
Visit http://naturehealthreach.com/staphcure
At first, I was really skeptical when she introduced me and my husband to this treatment, because we have tried lots of medicines that do not really work.
We used it for the first few weeks; we noticed rapid relief and decided to finish it for a month, then waited 2 weeks and went for a test.
The whole test results came out negative.
To still confirm the results, we decided to get more of the exact same herbal anti-infection remedy and gave it to our inner circle of friends and colleagues that have similar issues of STD or urinary tract infections that had discussed the matter with us in private…"
Likewise, they all came back and were marveled about how the herbal treatment helped flush off infections from their body system, and completely wipes out stubborn infections that are resistant to over-the-counter antibiotic drugs and injections.
Go here now to see the herbal remedy that cure staphylococcus and other infections.
Click here >> http://naturehealthreach.com/staphcure
And the best part of all is that they never felt even a slight headache when using it (no side effects at all).
At this point, let me introduce you to the Herbal Treatment Solution that worked for me, and helped me completely cure infections without any side effects at all…
"MAXI FLUSHA Herbal Capsules"
Effective Natural Herbal Treatment to Completely Flush off Drug-resistant Staphylococcus Infection, Sexually Transmitted Diseases, Urinary Tract
Infections, Toilet Infections From Your Body System …
Without Any Possible Comeback Ever Again!
"100% Natural HERBAL REMEDY for Staph Infection, STD and UTI"
The MAXI FLUSHA Herbal Capsules have been proven to help fight and flush off drug-resistant infections such as staphylococcus, syphilis, gonorrhea, herpes, Chlamydia, trichomoniasis, and other toilet infections etc.
It's purely herbal, NAFDAC Approved and certified, and it has no side effects on you.
Both men and women can use it for herbal treatment of infections and stubborn drug resistant diseases. To be taken 2 capsules morning before breakfast, and 2 capsules in the evening before dinner.
MAXI FLUSHA Herbal Capsules contains a powerful ingredient and extremely effective for the treatment of sexually transmitted infections and will help to boost your immune system to fight these antibiotic-resistant infections and venereal diseases.
You no longer have to bear the pains of the symptoms of these stubborn infections like discharge or drip from the vaginal or penis, burning sensation when urinating, frequent urinating, and itching on the private part.
MAXI FLUSHA Herbal Capsules have a strong impact in your body immune system to help flush off these infections… without any comeback!
One of the main ingredients that the Maxi Flusha Herbal Capsule contains is a powerful herb known as "Adansonia digitata" that can be found only in dry, hot savannahs of Sub-Saharan Africa.
One of the most well known effects of this powerful herb has to do with fighting infections/diseases and preventing it spread.
Once you start using this anti-infection herbal treatment, you will able to clear off stubborn, resistant infections and put an end to the symptoms in your body system.
You would see for yourself how far you have gone in helping yourself get rid of staph infection, STDs and urinary tract infections without any side effects at all.
But don't take my word for it, Below are actual testimonials we have received from people who used this MAXI FLUSHA Herbal Capsules Anti-Infection Solution and what they are saying about it…
I picked up the maxi flusha capsules from your store and I'm grateful to say it really worked for my husband to clear off his stubborn infections.
we've used other antibiotics for a long time now
to treat it but the symptoms kept coming back.
until a friend recommended d maxi flusha for us,this gets my highest recommendation n I will send more of my friends down to your office
Mrs. Edith – Maitama, Abuja
my wife and I order for your maxi flusha herbal capsules, all the way from katsina-ala lga in benue stae, the complete pack supply, and we are happy about the results we got.
After our last test, we were cleared, so I decided to let you know that this product did well for us. I have recommended it to our doctor so he can tell his other patients that are experiencing similar conditions.
am so glad to come accross your product, after spending heavily on this infection without any result. Thanks so much sir
Mr.& Mrs Nicholas (Benue state)
I had a concern that I have gonorrhea
my husband also gets a white milky discharge from the tip of his penis in the morning and some come out after urination.
we used 500mg of an antibiotic for some time, but unfortunately did not work
I stumbled upon your write-up online and with faith, I ordered for the Maxi Flusha anti-infection complete supply and we started using it
within 3 weeks of using the herbal treatment, the symptoms are gone. we also went for medical check up, and we were cleared. thanks so much easing our pains and saving us from this embarrassment
Anna (Warri, Delta state)
God is good! I had the same STD for almost 4 years and it caused me much turmoil and mental anguish. I tried several antibiotics but most of them were the same. After a week or 2, the symptoms are back.
The most embarrassing thing is the constant itching of my private part, even inside my sitting room.
I came across the Maxi Flusha herbal remedy for STD and decided to give it a try as something different. I went to the hospital and the result came out negative.
Now, I can say I am healed of the STD. I've ordered some for my wife to use as well, I'm so grateful and want other of my friends to know about the product
Mr. Sunnie – CBD, Abuja
for several years, my fiance' and I have been battling with heavy growth of staph infection.
it made us delay our marriage, affected my fertility and we were spending some good amount of money to treat it, not until I came across ur
site, and decided to try d maxi flusha
within d first 2 weeks, d discharge has stopped,
and no more itching or wormlike movement
after completing the required dosage, I decided
to do a test and the staph infection is now scanty
for both of us, and d entire symptoms have stopped.
within few weeks we repeated d test n it came
out negative
thanks for helping people with this wonderful product
seun – Gwarimpa estate, abuja fct
As you've just read, these people have experienced cure and permanent relief from staphylococcus, urinary tract infections and it symptoms after using the Anti-infection herbal capsules.
I wonder what happens when people begin to post experiences and testimonials on social media (Facebook, Instagram, Twitter etc.)
By word of mouth, there's so much huge demand… my inner circle friends and colleagues picked up 43 bottles of the anti-infection herbal treatment.
So, there are just 157 bottles remaining!
The anti-infection solution is spreading like wildfire… and demand is so heavy that most of the stocks are running out fast.
Right now, thousands of people will be seeing this website, that means the available stocks are extremely limited. I cannot assure you that you will be able to get it at the same discount price if you procrastinate.
So, go ahead and place your order now…
And if you go ahead and get it now, you will enjoy…
=> the discount introductory price
=> 100% FREE Shipping to every state in Nigeria
=> Payment at the point of delivery (or at your DOORSTEP)
This means you will pay for the products only when it has been brought down to you face to face by our courier company or delivery man.
Here's a breakdown of the price (depending on the option you're ordering for)…
2 bottles (60 capsules)
4 bottles (120 capsules)
(plus special bonus)
Yes, at this affordable discount price, you can say goodbye to infections, completely cure yourself of staph aureus, STDs and UTI, boost fertility and start living a healthy life.
NOTICE: Go Ahead and Order the Complete Package Supply
and Get Instant Access to a FREE BONUS
(Value: N7,500 – YOURS FREE!)
Here's how to get it: When you order for COMPLETE PACKAGE supply
of the Maxi Flusha Anti-Infection Capsules at N29,000… you will get
your own free bonus of the NADI CAPSULES for boosting immune system.
When you order today, you will get the Nadi capsules for free.
Remember, the free bonus is ONLY available to those that place their order right away. Don't procrastinate, else you may not get it.
So the deal is, place your order for the Maxi Flusha Anti-Infection Complete Package today, and you get access to the extra BONUS, absolutely FREE!
But there's one thing you should know… this is a limited time offer and will not be available for long.
It's either the prices goes up or we go out of stock…
When we go out of stock, you may have to wait until the next shipment, and it might be at a much increased price.
So, go ahead, order now and start using the herbal treatment to get rid of staphylococcus, sexual transmitted diseases and urinary tract infections, and start living a healthy life.
Best part is, there's absolutely no risk on your part.
Here's what I mean: You don't have to pay first before you get this product. We have payment on delivery option for you get the items. Once you place your order, my company sends the item to your state through our courier delivery service.
Once it get to your state, our delivery man picks up item and bring it to your provided address. Next, you collect your item and pay the money to the delivery man that brings it for you. No extra cost, no risk whatsoever!
Depending on your location in your state, delivery takes within 2 – 4 business days after you've placed an order.
Warning, for payment on delivery option (please, serious buyers only):
- Ensure that you have the cash available with you before placing order
- Ensure that you have gone through the website, understood the supply and prices for each option
- Make sure you are available for the delivery (nationwide delivery is within 2 to 4 working days, while Lagos receives it within the next day)
Follow the instructions below to place order, and get
the products delivered to your doorstep
(payment on delivery)
This means you will pay for the products only when it has been brought
down to you face to face by our courier service agent
Pay on Delivery Option Available to All States in Nigeria
Here's How to Order for Your MAXI FLUSHA HERBAL CAPSULES Today at the Special Discount Price
Depending on the option that you are ordering for…
*If you are ordering for "MINI PACKAGE"… indicate the code "MAXI FLUSHA MINI PACKAGE" in your text message…
*If you are ordering for "COMPLETE PACKAGE"… indicate it "MAXI FLUSHA COMPLETE PACKAGE" in your text message…
MAXI FLUSHA COMPLETE PACKAGE + Nadi – N29,000
Here's what to send to us…
Text the (the option you are ordering for) with the following information below…
that is, Maxi flusha complete package or mini package
- Your Full Name
2. Your Phone Number
3. Delivery Address (home or office address)
Send This Information as a text message to 081-7118-2702
Please Note: Your delivery address must include (your street name, town, local govt and state). Detailed Enough to make it traceable by our courier delivery man that will come around to deliver to you.
You will get a SMS and Call from us within 24 hours to confirm your Order Before we Parcel It Across to You.
Once we received your order, and your details are correct, you will receive an sms or call confirmation from us.
Your products will then be sent to our courier delivery and the items should get to you within 2-4 Days for nationwide delivery to other state, and 1-2 days for orders within Lagos state.
Note: The product will be packaged discreetly and no one else will know
what's inside, and every other information will be kept
private and 100% confidential.
Option 2
If you live in Abuja or Lagos, or nearby, you can also walk into our
marketing department office to pick up the products.
You will meet our team ready to give you these products at same price…
That is you Pay at our office, and get it instantly
Vantagesoft Marketing Enterprises
Block B, Suite 9, Primal Tek Plaza, Beside ECO centre,
by Mokola Bus stop, opposite Gowon Estate Market,
Egbeda-Idimu road, Egbeda, Lagos.
Suite 3B, First Floor, Shopping plaza beside NNPC Filling station,
opposite LHS school, Ilo awela road, by Toll Gate Bus stop, Ota
off Lagos-Abeokuta Expressway
Abuja office Hub: EFAB MALL Extension, suite A-75,
3rd Floor, off Gimbiya street, Garki, Area 11, Abuja, Fct
(Monday – Saturday 9am – 5pm)
Customer support line: 081-7118-2702
That is all you have to do to get access to the Maxi Flusha Anti-Infection herbal capsules.
Remember, staphylococcus and other drug-resistant infection are dangerous, life threatening diseases… they can damage your body system and make you infertile for life (whether you are male or female).
Do not waste another money on pharmacy drugs, antibiotics and injections that silently suspend the symptoms of staphylococcus, STDs and urinary tract infections, but make them remain in your body system… only for them to comeback bigger in the future or cause more havoc like infertility!
Why allow such menace destroy your marriage, home and life… when you can treat it once and for all using this specially formulated herbal remedy.
Maxi Flusha anti-infection herbal capsules have helped lots of Nigerian men and women permanently cure staph infection, sexually transmitted diseases and urinary tract infections, they testify it works effectively and saw results very fast.
Definitely your own case will not be different… it will cure you too!
Remember, the low discount price will only be available for an extremely limited time and once the available stocks are sold out, the price goes up.
Here's How to Order for Your MAXI FLUSHA HERBAL CAPSULES Today at the Special Discount Price
Depending on the option that you are ordering for…
*If you are ordering for "MINI PACKAGE"… indicate the code "MAXI FLUSHA MINI PACKAGE" in your text message…
*If you are ordering for "COMPLETE PACKAGE"… indicate it "MAXI FLUSHA COMPLETE PACKAGE" in your text message…
MAXI FLUSHA COMPLETE PACKAGE + Nadi – N29,000
Here's what to send to us…
Text the (the option you are ordering for) with the following information below…
that is, Maxi flusha complete package or mini package
- Your Full Name
2. Your Phone Number
3. Delivery Address (home or office address)
Send This Information as a text message to 081-7118-2702
Please Note: Your delivery address must include (your street name, town, local govt and state). Detailed Enough to make it traceable by our courier delivery man that will come around to deliver to you.
You will get a SMS and Call from us within 24 hours to confirm your Order Before we Parcel It Across to You.
Once we received your order, and your details are correct, you will receive an sms or call confirmation from us.
Your products will then be sent to our courier delivery and the items should get to you within 2-4 Days for nationwide delivery to other state, and 1-2 days for orders within Lagos state.
Go ahead, place order now to get the Anti-infection solution herbal capsules and start using them.
Be rest assured that this is the final destination to cure your staphylococcus, gonorrhea, syphilis, or any other urinary tract infections that you have or been battling with for months or years.
Get it here http://naturehealthreach.com/staphcure
Take 2 capsules, twice daily, send in your testimonials.
Mrs. Esther – customer support line 081-7118-2702


text:
Praise for Narthex & Other Stories
"This is H.D. at her best, speaking, making real for us the range of feeling of those possibilities at the edge of our known and defined experience which have not been spoken before. It is what I have called to myself the 'courage of the tenuous'—the quality in her which has most value for me as an artist, especially as a woman artist; the willingness to speak of what cannot be proved. What cannot, even, to be pointed to in the consensus world we precariously share with each other." —Diane Di Prima
H.D. (Hilda Doolittle) was a writer who is most famous for her Imagist poems, though her oeuvre extends far beyond this work. Living a life filled with close friends and stricken with relationship difficulties, Doolittle poured her personal stories into her many memoirs, novels, and verse and became a central figure of the Modernism. She was born in Bethlehem, Pennsylvania on September 10, 1886, and stayed in the state until she left Bryn Mawr College in 1911. After leaving the United States, H.D. spent the rest of her life writing, which ended on September 21, 1961, in Europe.
Michael Boughn has taught literature courses at the University of Toronto for 19 years. His own writing includes poetry, fiction, non-fiction, and essays. He is the author of H.D.: A Bibliography 1905–1990 (1993) and co-editor (with Victor Coleman) of Robert Duncan's The H.D. Book (2011). His recent book of poetry, Cosmographia: A Post-Lucretian Faux Micro-Epic, was shortlisted for the 2011 Governor General's Award for Poetry. His mystery novel, Business As Usual, was published in 2011. Great Canadian Poems for the Aged Vol.1 Illus. Ed is forthcoming from BookThug in 2012.
October 2011 | Fiction
5.25×8 inches | 130 pages
Condition: New


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For nearly 60 years, the Ford Motor Co. plant in Hazelwood, Mo., stood as a symbol of the St. Louis area's strength in auto manufacturing. Today, the shuttered plant is a symbol of an effective public-private partnership to transform a dormant property into an economic asset again.
Two years after the plant closed in 2006, Ford sold the site to Sacramento, Calif.-based Panattoni Development Co. The city of Hazelwood, meanwhile, took proactive measures to support a redevelopment vision.


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Tuesday, March 1, 2011
Sunset Glorious
5 comments:
All more beautiful than the next - thanks for sharing, lg. :)ReplyDelete
What a catalog, lg! These would make an amazing calendar! Just stunning...as Lynn said, one more beautiful than the next!!ReplyDelete
Wow! Excellent new re-branding, beautiful photos, and an absolutely marvelous header photo. I am happy.ReplyDelete
Hey Rob & Mandy-Thank you!ReplyDelete
Hey Talon & Lynn~ Glad that I could send you a sunset...or two!!ReplyDelete
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This artwork is my mother's. It touches my heart. (So gentle.) A thoughtful depiction of something sweet, tiny, and cute. 'Wa...
( works of art from the Art Institute of Chicago .) Top : "Two Sisters (On the Terrace)" by French artist...
Sunrise (Glorious!) Through the Thicket ... Through the Pines ... Through the Window (Veil) What do you see... through your veil? Today, s...


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Galaxy Digital saw first three quarter net income surge by 133% in 2019
Galaxy Digital, the cryptocurrency investment bank helmed by Mike Novogratz, pocketed $58.4 million in net income in the first three quarters of 2019, a 133% jump from the same period last year.
In a Q3 Financial report, the firm disclosed that it hit a net loss of $68.2 million in Q3, despite the overall gain in the first nine months of 2019. Over-the-counter trading, one of Galaxy Digital's three business lines, largely accounted for this loss with $43.3 million.
Still, there were some bright spots. The trading arm saw a 47% increase in total onboarded counterparties in Q3 over Q2.
Meanwhile, the asset management arm of Galaxy Digital had a total of $336 million assets under management by the of September 2019, $325 million of which was for the EOS Fund. The fund made several venture investments in Q3, include venture fundings to Loopland Group Holding, Versiart, Immutable, Predictive Pop, and FinCo Services.
As of September 30, 2019, the firm has made a total investment of $156.5 million, a $22,9 million decrease from the end of 2018, and had a total digital asset holding of $133.5 million, a $63.7 million increase from the end of last year.


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March 4th is still a few weeks away but it can?t come quick enough for me.
I?ve become wrapped up in all the intrigue that surrounds the heavyweight fight between the former world heavyweight champion David Haye and the WBC cruiserweight champion Tony Bellew.
Haye, who has ambitions of becoming a heavyweight world champion again, is of the opinion that he can dispose of the threat Bellew poses quite quickly, with Haye remarking to the media,
?I don?t think my fight with Bellew is any kind of test for me. It?s a fun fight for the fans, that?s all it is. A fight doesn?t have to be a test to be fun. Even if I have my worst night ever and he has his best. I?ll still knock him out.
?But that doesn?t mean I?m not going to prepare properly as I respect every fighter who climbs through the ropes.?
There also seems to be a mutual dislike between the two and Haye, talking about the current WBC cruiserweight champion, had this to say,
?Bellew won the WBC title but he did have a lot more help to the top than I did.
?I had to fight in final eliminators, I had to go to foreign soil and fight on a Don King promotion. I had everything against me.
?Bellew had his fight at his home football club for a vacant title. He had things a lot easier.?
Or maybe he just took the opportunity that befell him.
As for the future, Haye is aiming high, remarking,
?I need five more fights to prove I?m the best before I retire.
?The #1 target is IBF world heavyweight champion Anthony Joshua.
?Next is Tyson Fury. If he makes that comeback it will either be myself or Joshua in the opposite corner ? there?s two big fights to be going on with.?
It?ll certainly be interesting to see if Tyson Fury, after two fights with Haye were postponed due to injury, would ever entertain the idea of making it third time lucky.
As for Hayes objectives, let?s see if he can get past Bellew first shall we!
Haye Talks Bellew, Fury and Joshua
March 4th is still a few weeks away but it can?t come quick enough for me.


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Huge cash payments were made to Iraqi contractors out of the back of pick-up trucks, in scenes reminiscent of the "Wild West," he said.
Former CPA officials told the US Senate that sackfuls of money were often "tossed about like footballs".
The former head of the CPA and the administration have denied wrongdoing.
The CPA ran Iraq for a year between June 2003 and June 2004.
Paying cash
The allegations were made on Monday at a Senate hearing into the authority's practices called by Senate Democrats.
The senators described the management of the CPA's multi-billion dollar reconstruction programme as a "scandal".
Senator Byron Dorgan, who heads the Senate Democratic Policy Committee that held Monday's hearing, said "millions, perhaps billions of dollars have been wasted and pilfered".
Former CPA official Franklin Willis told the hearing there had been widespread abuse and waste of money at the authority.
He showed pictures of himself and other US officials holding plastic-wrapped bundles of $100 notes totalling $2m, which he said was used to pay a security contractor.
"We told them to come in and bring a bag," Mr Willis said.
He added that "a combination of inexperienced officials, fear of decision-making, lack of communications, minimal security, no banks and lots of money to spend" led to chaos that was typical of the Wild West.
The hearing also heard reports of overcharging and fraud.
The allegations follow a report by the inspector general which said the CPA had transferred nearly $9bn to the interim Iraqi government without any controls.
Two years after the fall of Baghdad, 80% of the $18bn earmarked by the US Congress for Iraq's reconstruction remains unspent.
In a reply to the inspector general's report, former CPA head Paul Bremer said it was wrong to assume that "western-style budgeting and accounting procedures could be immediately and fully implemented in the midst of a war".
Bremer said there was no functioning Iraqi government and services were primitive or nonexistent when the authority took over in 2003.
A Pentagon spokesman also denied that the CPA has provided inadequate financial controls.


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Harold J Kornblut, CPA in Latta, SC
Welcome to the Harold J Kornblut CPA website! Since our founding in 1982, we have grown steadily and rapidly, with a large team of accounting professionals ready to serve a continuously growing clientele.


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Michael Steven Green, Nietzsche and the Transcendental Tradition
Urbana, Illinois: University of Illinois Press, 2002. 216 pp. ISBN 10: 0252027353. Cloth: $29.95 (US)
Reviewed by R. Kevin Hill
As the title of the book suggests, Michael Green reads Nietzsche as deeply embedded in Kantian and Neo-Kantian patterns of assumption and argument. The argument proceeds in two stages. The first stage of the argument is to show this textually by tracing many of Nietzsche's characteristic philosophical concerns to his early encounter with the Neo-Kantian Afrikan Spir. Though one could argue from the same evidence that other Neo-Kantians, e.g., Kuno Fischer and Friedrich Lange, are equally important in shaping Nietzsche's thought (and a thorough historical study of this sort, which to my knowledge has not yet been attempted, would be a welcome addition to the Nietzsche literature), Green's emphasis on Spir is far from misplaced, for it is from Spir that Nietzsche appropriated arguments against the transcendental ideality of time (along with much else besides), and on the basis of which Nietzsche made his first move from a kind of transcendental idealism to the naturalism that would characterize his thought from this point forward.
Green also argues that naturalism, when combined with a Kantian epistemology of judgment, leads to the impossibility of true judgments, a position Green calls "noncognitivism" on an analogy with emotivist metaethical theories. To see why this is so, recall that for Kant, the attempt to vindicate non-empirical concepts like causality without providing a Lockean empirical genesis for them or taking them as brute innate ideas, depends upon their special relationship with the Kantian categories. The Kantian categories can be understood as syntactical forms (forms of judgment) which, when imposed upon the data of sense and the stuff of thought, yield fact-like truth conditions and sentence-like thoughts for them to correspond to, and it is only in this way that elements of thought can function as referring expressions and collections of sensory states can function as objects of reference. Without all this, there are neither facts nor thoughts to correspond to them, and hence no (empirical) truth. Yet the idea that the construction of, for example, causal connections and judgments about them can take place in time is difficult to make sense of. Fortunately for Kant, having already argued for the transcendental ideality of time, the idea that the data of sense are received and operated upon by the understanding atemporally in some sense is at least intelligible. Unfortunately for Kant, Spir argues quite persuasively that the transcendental ideality of time makes little sense itself.
At this juncture, a Neo-Kantian persuaded of the plausibility of both the Kantian account of the categories in the Transcendental Deduction and the implausibility of the Transcendental Aesthetic (at least as regards time) would appear to have two choices. The first choice would be to abandon Kantian epistemology in favor of some form of empiricism (though one might continue to regard some naturalized version of Kant's cognitive psychology as an empirical hypothesis). Though this option would allow Nietzsche to continue to write as if he regarded Kant as possessing some genuine insights into the workings of the mind, by strictly speaking abandoning Kant as epistemology, it would allow Nietzsche to avoid thorny questions of self-referential incoherence. For if it is true that the Transcendental Deduction reveals the necessity of an atemporal synthesizing self as a condition of the possibility of true empirical judgments, and naturalism is true, so that there cannot be any such self, then it is true that there is no truth. The second option is to say that Nietzsche bites this bullet and regards truth, even merely empirical truth, as a kind of illusion. If we take this path, judgments of fact will turn out to be surprisingly similar to moral judgments as seen by emotivists: their surface grammar would misleadingly suggest that they are fact-stating when actually, they are merely expressions of attitude, the products of our "drives."
Green embraces this latter alternative, and argues quite convincingly that Nietzsche is precisely such a global "noncognitivist." And it is the case that Nietzsche, even very late in his authorship, extensively in his unpublished notes but occasionally in his published works as well, writes as if there is some sort of deep problem with our truth-claiming practices. What is more, most of Nietzsche's discussions of this sort do seem to wear a Kantian ancestry on their sleeve, not least in their choice of terminology. Since Nietzsche did not, on the whole, publish the notes in which these reflections take place, it may not be necessary to choose between these two options as a matter of intellectual history: Nietzsche himself may have been quite uncertain about the implications of his commitments, and may have been in the process of trying to sort out what to do with them when madness descended and he fell silent. However that may be, we are greatly indebted to Green for opening a discussion of this long-neglected "transcendental" side to Nietzsche's thought. One hopes that this will be but the first of many studies exploring it.
Portland State University


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Is There Hope for Improving Drug Development Productivity?
I was recently reading yet another paper bemoaning the dropping productivity in drug development. The authors were discussing the most likely explanations for the decline, which were
- tighter regulation
- illusory decline (no actual decline)
- depletion of low-hanging fruit
- increasing risk aversion by the drug companies
- rising hurdles on safety
I mention this only because the paper was written in 1978 (Grabowski, Estimating the Effect of Regulation on Innovation). Yes, 1978. The tighter regulation they were talking about was the 1962 amendment which for the first time required that drugs demonstrate efficacy before being marketed.
Apart from all the other questions this paper, by the virtue of being from 1978 yet asking the same questions begs, I think the most interesting is: can drug development productivity improve? Is there hope?
Being an optimist, I would like to believe so. Frankly, even a realist would say that with less ability to price drugs high, and with declining R&D budgets, productivity must improve if the industry is going to survive.
So what can be done? Well, many people have different ideas, and unfortunately, there is no way to prove what will work, but let me toss out a few ideas.
1) Learn from Other Industries
We tend to be fairly insular in our approach to work. There is a lot to know in our own sub-specialization, and drug development itself is very complicated so it's hard to even learn about other drug development disciplines. How many people fully understand medicinal chemistry, toxicology, PK, clinical operations, clinical science, regulatory science, pricing, marketing, sales, reimbursement, and pharmacovigilance? Exactly.
Now, many people believe that innovation industries are different from traditional industries. I believe that. I would go further and argue that in many ways, our industry is sui generis.
But not in all ways. In some areas, you could make an argument there is a lot we can learn from other industries. Let me give you one example. Clinical operations, which is the execution of clinical trials, is essentially a supply chain problem. You have to bring together drug, physician, patient, case report forms, and data together efficiently and at the right time while managing risk and minimizing redundancies and excess capacity. Many would argue that we are just now starting to use modern supply chain management tools when we do this. For example, Walmart vendors know when an item is sold at a store real-time and can adjust their production accordingly. This minimizes waste and capacity gaps. CROs often only learn there will be a clinical trial when they receive the RFP.
Risk-sharing and information-sharing to make sure the risk is borne by the party best equipped to bear it is honed to a fine art in other industries. We can probably learn a lot from them, but I would hazard a guess that the number of supply chain experts from Walmart who now work in clinical operations in the drug industry is not high.
Similarly, it probably wouldn't be a bad idea to have some more industry-wide standards and coordination. Some people talk about precompetitive space, and that is fine, but I would like to see some coordination on the other end. For example, is it really necessary that each sponsor audit very CRO and CMO separately? Is it necessary that every sponsor negotiate separate and customized contract with each and every clinical site?
2) Better Animal Models
Anything multiplied by zero is… zero. Anything multiplied by 0.05 is… small. When you have a 5% (or even 10%) success rate, then you're swimming upstream. We need to raise our success rate. And what do we need to do that? Probably, better animal models.
We use "models" like tumor cells injected into mice or irritants injected into joints to mimic cancer and arthritis. We feel better when these models work, but the longer I'm in the industry, the less stock I find myself putting in those studies. Those models are just not very predictive. And unless we come up with better models, it will be a challenge to increase the success rate in drug development. Please see See my post named "Castalia."
There are several issues with the models, including the fact they're not actually replicating the biology as well as the fact that we generally use genetically identical rodents in our studies. So when you do an experiment with 20 mice with tumor cells, you're actually putting a cell line from a single cell into a single mouse twenty times. You're doing 1 mouse, not 20 mice. Now that's what I call personalized medicine.
We need better animal models or some other way to better handicapping success. Could it be from in-silica modeling? Could it be from applying modern decision-making theories to portfolio decisions? I don't know.
3) Better Feedback
Drug development has a long cycle time, and I would argue that it is what Kahnemann would call a low validation environment. It is difficult to determine whether experts can predict outcomes. Experts themselves may not know if they can predict outcome because feedback is rare and diffuse.
Many people would argue that it is difficult to improve a process without feedback.
For example, let's say a master medicinal chemist believe that changing the structure of a molecule will improve its performance. He will not know whether he is correct or not for 10 to 15 years, and he will not know whether it was that change or something someone else did that made a difference.
We try to set up interim metrics so that we can measure the chemist's performance. Many would argue that the interim metrics are almost never validated. In other words, we may not know if the metric toward which the chemist is working will affect the performance of the product. Only other master medicinal chemists are in a position to judge, and they may not know if they are correct.
The best we can say may be that the decisions under the best circumstances are consistent. We may have good precision, yes. But can we can say that they are accurate? Without validation, it is not easy to tell whether what you're doing is helpful or detrimental. There are instances where the unintended consequences may be worse than the intended consequences. Please see my "New Thinking" post for discussion of P450 and Lipinski's rules and how they may lead us astray.
But let's not single out the chemists – these unvalidated metrics probably apply to just about every function, and more importantly, it's the clinical developers who are failing to give feedback to the early stage people. So there's lots of accountability to go around.
We need feedback, and we need feedback not on drugs that work but on drugs that fail. 90 – 95% of drugs fail. If you were to ask most people how much time they spend analyzing failed drugs, they would probably give a low number somewhere close to zero. Over 90% of the data necessary to improve drug development process lies in failed drugs. The remaining 5-10% of data may be of limited use without a comparator group. You could argue that looking at what successful drugs look like is less important than looking at the differences between successful drugs and unsuccessful one. Please see "Whence the Low Productivity" post for more discussion on feedback.
The point is that one of the most important things we need to do may be to spend a lot more time giving and getting feedback, and validating the interim metrics we work towards.
4) Design Thinking (Empiricism)
As I talk about in another post, and as others have noted, we probably think we know a lot more about biology than we actually do. I'm all for rational drug design and in-silico modeling but I think we need a lot more data and knowledge before we can make those work.
Instead, I'm in favor of what Trevor Mundel in April 2012 issue of Nature Review Drug Discovery said: it's hard to figure out what is going to work until you take it into people, so take them into people and get some data before making the decision. Some people call this experimental medicine.
In other fields, this is called design thinking (Ideo Labs), rapid prototyping, or lean startup. It's an engineering mindset, when you can't analytically solve a problem, you prototype and see what you get. It's really empiricism, but that I guess that word has a negative connotation in many circles.
5) Better Clinical Development
Clinical development is where the bulk of the spending is in drug development. We're not going to get the needle to move on productivity without improving clinical development. I touched on one aspect of clinical development that could be improved already in section 1. And of course, many people are working on lowering costs and timelines by outsourcing to developing countries.
In addition, I think adaptive clinical studies will help improve clinical development significantly. I have a textbook on adaptive clinical trials that goes into more detail.
One additional way to improve productivity which is in theory attractive but in practice difficult is multiplexing. Multiplexing in clinical development is called factorial design.
When I was in college, I recall that labs would have Drosophila screening parties. Dozens of graduate students would come together from all over the world, sit down, and sort through millions of irradiated fruit flies. Each student would be looking for a particular mutant, and if anyone saw one with that mutation, he would give it to the right student. This way, they wouldn't each have to sort through a million files.
Drugs are a bit like irradiated fruit flies in that sometimes they have biological activity but you don't know what indication they will work in. At the same time, multiple trials are often being run in for the same indication but for different drugs.
I know it's an unorthodox suggestion to test multiple drugs in the same study, and it's also discomfiting to think about putting a drug in multiple indications at the same time. And there are of course issues of IP, competing drug companies' interests, and potential issues with interactions. However, the way we're doing drug development, one drug in one study for one indication at a time is somewhat akin to a lone grad student screening a million fruit flies for one mutation. There has got to be a better way.


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In general the operation of unmanned aerial vehicles (UAV) for commercial purposes is illegal in the U.S. But in the last few months the Federal Aviation Administration (FAA) has issues grants of exemption to six companies for commercial UAVs for general aerial surveys (Trimble, Woolpert) and specifically for construction monitoring (Clayco, Inc), agriculture (Advanced Aviation Solutions), on and offshore oil and gas inspections (VDOS Global), and real estate (Douglas Trudeau, Realtor).
In 2011 the FAA fined a UAV operator $10,000 for flying a radio-controlled airplane recklessly over the University of Virginia campus to make a commercial for the University. Early in 2014 a National Transportation Safety Board (NTSB) Judge ruled that the FAA ban on flying UAVs was not legally binding. The judge said that the FAA had historically exempted model aircraft from the statutory definitions of aircraft. March 7 the FAA issued a notice saying that it was appealing the decision to the full National Transportation Safety Board. The FAA cited its regulation of model aircraft under the FAA Modernization and Reform Act of 2012 (FMRA) which states that "if a model aircraft operator endangers the safety of the National Airspace System, the FAA has the authority to take enforcement action against those operators for those safety violations." November 18 the NTSB supported the FAA saying that an unmanned aircraft is subject to enforcement of FAA regulations prohibiting reckless operation of aircraft.
The FAA has issued 14 grants of exemption for commercial operation of UAVs. The first was to a manufacturer of UAVs used in film production. The FAA found that a "grant of exemption is in the public interest. Therefore ... Astraeus Aerial is granted an exemption ... to the extent necessary to allow Astraeus to operate unmanned aircraft systems (UAS) for the purpose of scripted, closed-set filming for the motion picture and television industry."
The requirements for operation of the UAV imposed by the FAA are restrictive (Astraeus Aerial Grant of Exemption);
- The UAV must weigh less than 55 pounds.
- The UA can not be flown at a ground speed exceeding 50 knots.
- Flights must be operated at an altitude of no more than 400 feet above ground level (AGL).
- The UA must be operated within visual line of sight (VLOS) of the pilot at all times.
- All operations must utilize a visual observer (VO). The VO and the pilot must be able to communicate verbally at all times.
- The pilot must possess at least a private pilot certificate and at least a current third-class medical certificate.
- The pilot must have accumulated and logged a minimum of five hours operating the UAV.
- The UAV may not be operated directly (within 500 ft) over any person, except authorized and consenting production personnel.
- Each UAV operation must be completed within 30 minutes flight time or with 25% battery power remaining, whichever occurs first.
- The operator must obtain an Air Traffic Organization (ATO) issued Certificate of Waiver or Authorization (COA) prior to any operations under this grant of exemption.
- The UAV must remain clear and yield the right of way to all other manned operations and activities at all times (ultralight vehicles, parachute activities, parasailing activities, hang gliders, etc.).
- UAV operations may not be conducted at night.
- The UAV may not be operated by a pilot from a moving device or vehicle.
- The UAV may not be operated less than 500 feet below or less than 2,000 feet horizontally from a cloud or when visibility is less than 3 statute miles.
This is certainly not going to allow the deployment of long range UAVs like the Silent Falcon with a daytime endurance estimated to be 5 to 12 hours depending on wing configuration, weather, and flight profile. Night-time endurance is estimated at 3 to 5 hours. For example, equipped with LiDAR this could be used for transmission line monitoring for vegetation management at a much lower cost than a manned helicopter.
December 10 the FAA issued grants of exemption to four additional companies;
- Clayco, Inc. , a general contractor, to operate unmanned aircraft systems (UAS) for the purpose of aerial imaging to monitor and ensure safety of construction sites.
- Trimble Navigation Ltd, a provider of advanced location-based solutions, to allow Trimble to operate the UX5 UAS for the special purpose of precision aerial surveys that consist of still photographs taken by an onboard camera.
- VDOS Global, LLC, a provider of aerial inspection services to the on and off-shore oil & gas industry, to allow VDOS to operate unmanned aircraft systems for the purpose of flare stack inspections on 14 Shell Oil Gulf of Mexico production platforms with all platforms beyond 12 nautical miles of the coast of the United States.
- Woolpert, Inc, a design, geospatial and infrastructure management firm, to allow Woolpert to operate the Altavian Nova Block III unmanned aircraft system for the special purpose of precision aerial surveys that consist of still photographs taken by an onboard camera.
January 5 two more exemptions were granted;
- Douglas Trudeau, a realtor, to operate unmanned aircraft systems for the purpose of aerial videography/cinematography and augment real estate listing videos.
- Advanced Aviation Solutions to operate unmanned aircraft systems for the purpose of aerial imagery to support agriculture.


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