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Human organs 'could be grown in animals within a year'
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July 19th, 2013 (11:54 AM). Edited July 19th, 2013 by KriegStein.
Nuclear Reactor
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Originally Posted by
Looks like it's finally happening, folks. This issue is multifaceted and I will try to bring a number of themes to light:
1) What do you think about creating a human-animal chimera? Is this breaking the "barriers" of nature? Or is the only barrier what human ingenuity cannot accomplish?
2) I don't think this technique will be extended to humans, for obvious reasons. I can put that previous statement this way: these animals are being used quite simply because they are animals. Is this a step up from what we're used to in terms of using animals as resources? Would it make a difference if you harvested both the meat and the organs? Are animals more than things and are they being commodified too far? Does the need for organ transplants outweigh the ethics of using animals to harvest organs?
3) The United States is one of the most technologically advanced countries in the world - much of the high tech innovation going on still occurs there. This is no doubt on the cutting edge of the life sciences. Do you think such advances would be possible in the United States? Do the current political and social climate inhibit scientific development from occurring? If so, is this something worth changing?
I remember the thread about duck-chicken chimeras, and this is along the same vein, but at the same time quite different. Happy discussing!
Considering my lenient moral in science...
1. I say: Go for it dammit! I find these things always fun to study. (Although I like biomechanics more)
2. Hey if a pig can give a person a new heart I say go for it. And I think this technique WILL be extended to humans. But not in legal places o course.
3. Bah... It could but it wont. sadly...
EDIT: I meant Biomechatronics. not biomechanics.
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SEP 24, 2013 - San Francisco Chronicle
A Must Read - Share
BEIRUT (AP) — With the world's attention on Syria's chemical weapons stockpile, international aid organizations and opposition groups are warning of widespread food shortages across the country, especially in besieged rebel-held enclaves near the capital.
The suburbs, a major battlefront in Syria's civil war, were the site of the Aug. 21 attack that a U.N. report found included the use of the nerve agent sarin.
State-run SANA news agency said the blast hit the contested district of Tadamon, which has seen months of fighting between the military and rebels seeking to topple President Bashar
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subset: commoncrawl


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Staff Report
Published Sept. 27, 2012
A Massachusetts real estate investment trust has bought the Meridian Building, a 17-story office tower in downtown Columbia.
CommonWealth REIT paid $60 million for the class A office building at 1320 Main St., according to a deed transfer filed Sept. 18 in Fulton County, Ga. The building's developer, Holder Properties, is based in Atlanta.
The 333,000-square-foot Meridian Building is the second major real estate deal in the Central Business District in the past week.
Last Thursday, Sept. 20, locally based AgFirst Farm Credit Bank said it intended to buy the 17-story, 300,000-square-foot Bank of America Plaza at 1901 Main St. No purchase price has been announced.
AgFirst said it will move its operations and about 380 workers into 100,000 square feet of office space at the BOA Plaza.
In its quarterly report issued Aug. 8, CommonWealth announced that in May it had entered in an agreement to buy the Meridian Building, adding that it expected to close during the third quarter.
The property, CommonWealth noted in the report, is 92% leased to 17 tenants. The average lease term is 8.8 years, the report added.
Completed in 2004, the Meridian Building was the first high-rise at that time to be developed downtown in 15 years. The office building is Energy Star certified and features a rooftop garden, two pocket parks, a restaurant, banking facilities and a fitness center.
CommonWealth owns a number of properties in the Columbia area, including four buildings at the Synergy Business Park at Interstate 20 and Bush River Road.
CommonWealth is an office and industrial real estate investment trust. As of June 30, it owned $7.2 billion of office and industrial properties in 31 states, Washington, D.C., and Australia.
Besides the Meridian Building, Holder has developed three other properties in downtown Columbia. These properties are Adesso, a 110-unit condominium building at the corner of Main and Blossom streets, Aspyre at Assembly Station Apartments, a 400-unit student apartment complex at the corner of Assembly and Whaley streets, and Main & Gervais, a 205,000-square-foot, class A office building located across from the Statehouse.


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Cherry Crisp
From EatingWell: The Simple Art of EatingWell
A fruit crisp offers the luscious flavor of a fresh fruit pie without the fuss of making a crust. Celebrate the arrival of cherries with this rich-tasting crisp. The nut-studded topping works great with other fruit combinations too.
Makes: 8 servings, 1/2 cup each
Active Time:
Total Time:
Nutrition Profile
Heart healthy | Low sodium | Low cholesterol | Low saturated fat | High fiber |View Our Nutrition Guidelines »
- 1 1/2 pounds sweet cherries (5 cups), fresh or frozen, pitted
- 1 cup raspberries, fresh or frozen
- 1/3 cup granulated sugar
- 1 tablespoon cornstarch
- 1 tablespoon lemon juice
- 1 tablespoon kirsch or brandy (optional)
- 2/3 cup whole-wheat flour
- 1/2 cup old-fashioned rolled oats (not instant)
- 1/2 cup packed light brown sugar
- 1 teaspoon ground cinnamon
- Pinch of salt
- 1 tablespoon butter, cut into small pieces
- 1 tablespoon canola oil
- 3 tablespoons frozen orange juice concentrate
- 1 tablespoon chopped almonds or walnuts
- Preheat oven to 375°F. Coat an 8-inch-square baking dish (or similar 1 1/2- to 2-quart dish) with cooking spray.
- To prepare filling, combine cherries, raspberries, granulated sugar, cornstarch, lemon juice and kirsch (or brandy), if using, in a large bowl; toss to coat. Place the filling in the prepared baking dish. Cover with foil. Bake for 20 minutes.
- Meanwhile, make topping. Mix flour, oats, brown sugar, cinnamon and salt in a medium bowl with a fork. Add butter and blend with a pastry blender or your fingertips. Add oil and stir to coat. Add orange juice concentrate and blend with your fingertips until the dry ingredients are moistened.
- After 20 minutes, stir the fruit filling and sprinkle the topping evenly over it. Sprinkle with almonds (or walnuts). Bake, uncovered, until the fruit is bubbly and tender and the topping is lightly browned, 20 to 25 minutes more. Let cool for at least 10 minutes before serving. Serve warm or at room temperature.
Per serving: 245 calories; 5 g fat (1 g sat, 2 g mono); 4 mg cholesterol; 51 g carbohydrates; 22 g added sugars; 3 g protein; 4 g fiber; 36 mg sodium; 331 mg potassium.
Nutrition Bonus: Vitamin C (38% daily value)
Carbohydrate Servings: 3
Exchanges: 1 starch, 1 fruit, 1 carbohydrate, 1 fat
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Recipe Categories
- Health & Diet Considerations
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- Low sodium
- Heart healthy
- High fiber
- Low cholesterol
- Ease of Preparation
- Easy
- Total Time
- More than 1 hour
- Servings
- 8 or more
- Preparation/ Technique
- Bake
- Meal/Course
- Dessert
- Type of Dish
- Desserts, fruit
- Ethnic/Regional
- American
- Publication
- The Simple Art of EatingWell


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All Comments (21)
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Great pussy`s for my


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Does Literate Haskell support indexing function names, typeclasses and variable references? Is there a filter I can run on Literate Haskell source that will do this and give me either a nice PDF manual or a hyperlinked HTML document.
These are a really nice features of noweb and CWEB which I think it would spur widespread adoption of Literate Haskell.
As an example, look at the word count program written in CWEB. The code chunk on the first page in item #4 is footnoted with where that code is used. LHS doesn't support chunks but I'd like to know where the code is being used:
Comment describing func.
func = id
Used in: (X.Y.Z.f, A.B.C.g, Section 1.5)
func2 = indefined
Used in: (A.B.C.x, Section 2.1)
And additionally an index that aggregates all the function names and variables along where they're referenced in the document and by other functions etc.


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This topic is archived and can not be replied to any more.
|TAM : More 1 A332, A332 On GRU-EZE, GIG-EZE (A320) posted Sat Jun 10 2006 07:35:51 by LipeGIG
|CO To Put ERJ's On EWR-MSY (and Other Info) posted Fri Nov 18 2005 00:26:36 by MSYtristar
|LH To Drop FRA-GRU-SCL A340-600 Flight! posted Wed Dec 7 2005 00:34:44 by LipeGIG
|TAM Upgrading Onboard Service To EZE And SCL posted Sat May 7 2005 17:55:59 by EMB195ER
|TAM To Fly GRU-MXP Effective March 30 With A332 posted Fri Dec 8 2006 03:06:54 by LipeGIG
|TAM To Fly GIG-CDG And GRU-MXP (With B772?) posted Sat Aug 26 2006 13:30:48 by Hardiwv
|SAA Plans Return To EZE And Twice Daily To GRU posted Fri Aug 18 2006 13:15:58 by Hardiwv
|TAM Goes Double-daily On MIA-GRU posted Fri Feb 6 2004 08:23:47 by MAH4546
|AA Likely To Add More MIA-GRU/EZE Service posted Wed Feb 4 2004 05:06:27 by MAH4546
|SAA Soon To Go Daily On JNB-GRU Route! posted Mon Oct 27 2003 00:14:31 by Dellatorre


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May 24, 2016
The Mississippi Department of Transportation will temporarily close an Interstate 20 ramp in Meridian Wednesday and Thursday.
The I-20 westbound Exit ramp 154 in will be closed from 6 a.m. on Wednesday, Oct. 21 until noon Thursday, Oct. 22.
Exit 154 is the exit ramp for Highway 39 North, and Highway 19 South, and is the first exit when traveling westbound through Meridian.
This temporary closure is necessary for crews to do concrete inlay work at the intersection of the exit ramp and Highway 39 North.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


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Barrymore's Lifetime Friendship With Applegate
By Celeb Stink 6 years ago
Drew Barrymore on her longtime friendship with Going the Distance co-star Christina Applegate. She says "We were in the same dance troupe when we were kids... She taught me never to wear spandex with a belt." (KL/TG/IG)
Copyright 2010 WENN


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Megan Fox has two clubbed thumbs!
In 2008 Megan Fox become known as the sexiest woman in the world according FHM (after her appearance in the movie 'Tranformers'); today she is probably more well-known for her brachydactyly type d thumbs!
Megan Fox has a minor physical anomaly on both hands: the first super hot babe who has stubby toe thumbs - a.k.a. clubbed thumb, stub thumb, toe thumb, potter's thumb, hammer thumb or club thumb).
The essential characteristic concerns a rather remarkably broad nail phalange of the thumb (see the 1st and 2nd pic of this unique Megan Fox gallery below); in medical science this thumb characteristic is known as brachydactyly type-d.
Enjoy this unique Megan Fox toe thumb collection!
Megan Fox thumb impression from the Armani campaign:
After the Megan's thumbs got replaced by a standin the 2010 Superbowel commercial, a few months later her thumbs were photoshoped in the Armani jeans & underwear campaign. Enjoy the 'naughty' Armani jeans-movie in the right column!
Megan Fox thumbs - right hand pics:
Next to the 'clubbed thumb', Megan Fox's right hand appears to be featured with relatively long pointer finger (a typical characteristic of the hand of females - in males the ring finger is usually longer than the pointer finger).
Megan Fox thumbs - left hand pics:
Another typically characteristic is the 'independent head line' [in medical science: a 'distally displaced proximal transverse crease'].
Combined with the long pointer finger, this could be recognized as a typical characteristic of a woman who wants to be in control (according theories in modern hand analysis).
NOTICE: Megan Fox describe's herself as a "control freak".
Despite the Megan Fox thumb story, she has often been described as the "next Angelina Jolie" - for multiple reasons, including her 9 tattoes: featuring e.g. the face of Marilyn Monroe on her right forearm (see the 1st photo on the left - in 2012 Megan let it take away after she became a mother), a Yin-Yang on her left inner wrist, and a line adapted from William Shakespeare 's play King Lear at her right shoulder that reads: "We will all laugh at gilded butterflies".
In 2010 Megan's thumbs were also 'photoshoped' in the photoshoot of the Armani jeans & underwear campaign (one of the photoshopped Megan Fox pictures is presented on the left above a picture displaying the real shape of her thumb).
Her (sensual) acting skills become unfolded in this short-movie from the Armani jeans & underwear campaign... with not only her thumbs uncensored!
Megan Fox's Obsessive Compulsive Disorder (OCD) might relate to various structures of her hands (according PsychoDiagnostic Chirology).
More Megan Fox thumb stories:
• Megan Fox toe thumbs
• Megan Fox clubbed thumbs


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Authorities say a Newport man has been arrested after assaulting and kidnapping his pregnant ex-girlfriend.
Aaron Dean Brock, 18, of Clements Drive was arrested Thursday in Rowan County on warrants from Carteret County.
Brock was charged with communicating threats, second-degree kidnapping, assault on an unborn child and two charges of assault on a female.
Authorities say Brock fled Carteret County after the incident. The girlfriend's name is being withheld because she is a juvenile, according to Carteret County Sheriff's Office.
Brock is accused of punching and kicking the girl in the stomach while also holding her against her will and displaying a knife, according to the CCSO. The incident allegedly occurred on Clements Drive in the Riverwoods subdivision.
Bond was set at $10,000.
Location, ST | website.com


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Madhya Pradesh: Hoshangabad, Harda, Khandwa - The UPA government will struggle to take credit for the DBT scheme in BJP-ruled Madhya Pradesh, where schemes that seek to provide similar benefits are already in place. Simultaneously, should things go wrong, the UPA would be spared the flak because DBT is indistinguishable on the ground from the states measures electronic transfer of funds or enhancing the scope of financial inclusion, both of which necessitate opening of bank accounts.
The Madhya Pradesh Model of Financial Inclusion and Direct Benefit Transfer weaves in benefits of several state and central schemes. It has named the project Samagra Samajik Suraksha Mission.
The government has been depositing money in the accounts of farmers after purchasing wheat, starting before DBT was introduced, besides making electronic transfers of MNREGA payments. In the last few months, 1,700 ultra small banks (also called community service centres) have been opened and 1,300 more are being added.
Unlike DBT, which is being implemented in Hoshangabad, Harda and Khandwa districts, the states initiatives are relatively hassle-free because they are not linked to the Aadhar card yet. Using biometric authentication, the beneficiary is provided benefits at the nearest USB. The RBI norm of one USB for a population of 2,000 did not suit a large state like MP, so the government changed the criterion to one USB every 5 km.
The USB works to the banks advantage also because it does not have to spend on infrastructure. While distributing benefits of government schemes, it can also convert the no-frills accounts to regular savings accounts.
Against this background, the idea of opening accounts for benefits such as LPG or kerosene under DBT has not really enthused potential beneficiaries, who fail to understand how they stand to benefit. They dont know or care which government is behind the idea.
Daily wage earners like me will have to pool money to buy kerosene at the market rate and then wait for the subsidy to reach the bank. I dont see any benefit in it. What does my family eat till then? says Janardan Shravankar, who tarvels daily from Hoshangabad to work at a highway dhaba.
Shakti Singh Chouhan, sarpanch of Jasalpur, has an LPG cylinder in mind. Hamara paisa hamko vapas de rahe ho, he says questioning the DBT. He claims, Theres a rumour that the government will deduct tax before depositing the subsidy amount.
When a sarpanch is influenced


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The IRS deadline of April 18th is coming soon. File fast, for FREE with TurboTax Federal Free Edition.
BuddhaX is a new exercise concept that combines breakdance with power vinyasa yoga to create breakflow, a unique series of integrated dance moves and yoga poses. When done at a continuous, reasonable pace you can burn between 500 and 1,500 calories per hour (not to mention, look really cool doing it). Here, co-founder Japanese B-boy A.T.S of Rock Steady Crew demonstrates the BuddhaX CC Push-up, a core-focused movement that works out every single muscle. Try it — he swears anyone can do!
Move toward a seated pose, balancing on your left palm with your foot flat on the floor. Distribute about 65 percent of your weight on your foot (35 percent on your hand). Tighten your core muscles and breathe steadily throughout the progression of movements.
Bring your left heel down to the floor and start to shift your weight onto the left heel, beginning to twist your body to the left side.
Continue to shift your weight and twist your body to the left placing your right hand on the floor and pivoting your left foot so your weight shifts from the heel to the outside edge of the foot and then to the toes. As you shift your weight left, your right foot will naturally want to come off the ground. As it comes off the ground, carefully bend your knee.
Fully shift your weight and evenly distribute it between to your left toes and both hands, which are now flat on the floor making sure to keep your neck aligned as shown. Maintain the bend in your right knee.
With your chest facing the floor and maintaining the bended right knee, bend your elbows into a push-up and then push back up to almost straight arms (always have a micro-bend in the elbow for joint protection).
Slowly shift your weight back around back to the starting seated pose while maintaining the focus on a strong core. Make a goofy face and smile! (Then repeat on the other side.)


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Going with the flow
Religion | Bible Study Fellowship joins controversy by adopting the 2011 NIV Bible
When Kitty Oman heard that Bible Study Fellowship had decided to switch to the 2011 redo of the New International Version in its teaching materials, she was concerned. She had heard of the controversy surrounding that translation, so she did some research about the issue on her own.
What she found out eventually led her to write a letter of resignation from her position as a BSF small group leader. In it she said, "BSF has been an amazing tool in my life to grow in Christ and be blessed with godly relationships that are precious to me," but added "with sadness" that she thinks the decision to use the new NIV has "opened the door" for distortions of truth in the ministry. Others are also leaving BSF over this issue.
For readers who may not be aware of the controversy surrounding the 2011 NIV, it began in 1996 with publication of the NIV Inclusive Language Edition (now discontinued) and continued in the early 2000s with release of Today's New International Version (TNIV). Critics such as Wayne Grudem decried many of the changes made to the widely used 1984 NIV, particularly the use of "gender neutral" language that led to plural pronouns such as "they" replacing single masculine ones like "he."
Critics also disputed the translation of some important verses about gender issues. For example, 1 Timothy 2:12 changed from saying women should not "have authority" over men, to women should not "assume authority": That understanding could allow women to be pastors and elders as long as their church duly appoints them.
'It's one thing to translate God's Word in terms the culture will understand; it's another to do so in terms the culture will accept.' —Harry Reeder
The Committee on Bible Translation (CBT), which is responsible for the NIV, took the criticisms into account when it produced the 2011 update, but the changes it made were not sufficient for most of the critics, since many of the plural pronouns and the 1 Timothy 2:12 wording remained. The critics are complementarians—they say men and women have some roles that are different but complementary—but the CBT includes egalitarians who downplay differences.
Critics worry that the CBT is compromising the integrity of Scripture. For example, Birmingham pastor Harry Reeder says the 2011 NIV is "more committed to being affirmed by the culture than communicating God's Word to the culture. It's one thing to translate God's Word in terms the culture will understand; it's another to do so in terms the culture will accept."
But CBT member Craig Blomberg, a Denver Seminary professor who describes himself as a "mild complementarian," says the CBT sought to apply research findings on English language usage and to produce what he calls an "optimally equivalent" translation. Regarding the specific example of 1 Timothy 2:12, Blomberg says "assume authority" is a neutral translation that the CBT thought did not tilt the exegesis one way or the other.
BSF Executive Director Susan Rowan told me BSF "believes and teaches the full inerrancy of the original text of Scripture," and "the BSF leadership conducted thorough research and consulted with several scholars to assure that the NIV 2011 continued its tradition of accuracy to the original manuscripts."


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Dezhi Hong, Ben Zhang, Qiang Li, Shahriar Nirjon, Robert Dickerson, Guobin Shen, Xiaofan Jiang, and John A. Stankovic
April 2012
A mobile phone, as a pervasive device, has great potential in human wellness monitoring. In this demo, we first present the design and implementation of our hardware - SEPTIMU. SEPTIMU consists of a small baseboard and a pair of tiny sensor boards embedded inside conventional earphones. The baseboard provides power conversion and data communication through the normal audio jack interface. The embedded sensor board is 1×1cm2 and integrates 3-axis accelerometer, gyroscope, thermometer, photodiode and microphone. Secondly, we evaluate SEPTIMU using a mobile application that continuously monitors body posture and provides feedback to the user.
|Publication type
|Published in
|Proceedings of The 11th ACM/IEEE Conference on Information Processing in Sensor Networks


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55. "A Man For All Seasons" (1966)
A sincere and prestigious mounting of the Robert Bolt play about the staunchly Catholic Sir Thomas More's refusal to recognize King Henry VIII's divorce, it's every bit as stately as that description sounds, and every bit as dull. Paul Scofield reprises his theatrical role as Moore, and Orson Welles and John Hurt lift things in supporting roles, but Fred Zinnemann's game direction can't overcome the verbosity and heaviness of the film's stage origins.
54. "Million Dollar Baby" (2004)
The Academy's love for Clint Eastwood knows few limits, as evidenced by the 4-major-Oscar sweep for this extremely familiar-feeling underdog boxing story. That the boxer was a woman (Hilary Swank, getting her second Best Actress Oscar) was really the only unusual element to an admittedly solid, well-made drama, barring the sucker punch ending.
53. "Shakespeare In Love" (1998)
Much-denigrated after the fact when it beat "Saving Private Ryan" to the gold (especially after a bitter and bad-tempered Oscar campaign), "Shakespeare In Love" has aged reasonably well. It's hardly an all-time classic, but it's an enjoyable and moving upmarket rom-com, with a cast having a ball, and a sparkling script from Tom Stoppard.
52. "Ben Hur" (1959)
The most epic of all the epics (it's the longest Best Picture winner ever, beating 'Return Of The King' by ten minutes, and ties that film and "Titanic" for most ever Oscar-wins), "Ben Hur" remains a real wow on the big screen even now. It's overlong and preachy, and Charlton Heston is a bit ropey as the title character, but remains a staggering achievement, with some of the finest action sequences in the history of the medium.
51. "Mrs. Miniver" (1942)
Overshadowed a bit these days by some of its contemporaries, William Wyler's WWII melodrama, about the life of a well-to-do British woman in the early years of the war, is old-fashioned and unabashed in its role as propaganda. But it's well-executed, stirring, and has a great lead performance from Greer Garson (whose own six-minute acceptance speech remains the longest in Oscar history).
50. "The Sting" (1973)
A slick, thoroughly enjoyable, totally empty period con-caper re-teaming "Butch Cassidy and the Sundance Kid" stars Paul Newman and Robert Redford as grifters taking on Robert Shaw's hoodlum. Breezy and fun, with great chemistry between the stars, but so lightweight you fear a gust of wind might blow it off the screen.
49. "Slumdog Millionaire" (2008)
Danny Boyle's unexpected smash has its problems, we'll acknowledge, mainly in its scripting and the very occasional whiff of poverty porn. But it's hard to think of a recent Best Picture winner that's as bright and vibrant as this one, so full of energy and invention. We'd seen crowd-pleasers win Best Picture before, but never one that looked or sounded like "Slumdog Millionaire."
48. "Ordinary People" (1980)
Robert Redford, proving early how much time the Academy has for actors-turned-directors, won Best Director as well as Best Picture for this unassuming but very well-performed drama detailing the slow disintegration of a family in the wake of the death of a son. Among several notable elements is Timothy Hutton's performance that should have launched him to much greater heights of stardom than he subsequently achieved.
47. "Gandhi" (1982)
Richard Attenborough's ambitious three-hour epic telling of the legendary Indian political figure makes a decent run at chronicling the story of Gandhi's life, but doesn't do much beyond that. It's a rather shallow and personality-free take, afraid to ever take much of a viewpoint on anything. Still, it's impressive in the broad strokes, and in the occasional effective little scene too.
46. "Argo" (2012)
Facing the inevitable Best Picture backlash even before it won, we still stand beside the grown-up entertainment of Ben Affleck's "Argo." Sure, it tinkers with the truth a bit, and the director isn't the strongest choice in the lead, but it's genuinely, knuckle-gnawingly tense, and has a deep bench of supporting players, with fine work from everyone from Bryan Cranston to Scoot McNairy.
45. "The Departed" (2006)
A bit of a comic-book trifle when compared to Martin Scorsese's best work, with a couple of whopping misjudgements (god, that final shot...), but when "The Departed" works, it really works. Most notably in William Monahan's hilariously profane script, a couple of cracking suspense sequences, and a fantastic, perplexingly undervalued Matt Damon performance at the center.
44. "The Artist" (2011)
While the Michel Hazanavicius film seems on the surface to have been a challenge for the Academy, being in black and white and silent, it's still a very escapist film with not a huge amount of substance there once you take away the gimmicks of its presentation. Affectionate and perkily performed (Jean Dujardin got the Oscar, but we fell most for Bérénice Bejo), it still doesn't feel like one for the ages.
43. "Rain Man" (1988)
Two and a half decades later, what really stands out about this solid Barry Levinson film is not the much-parodied Best Actor-winning Dustin Hoffman performance, that became an early byword for goosing a character's disability or an affliction to an Oscar, but just how good Tom Cruise is, in the less obvious role as the conflicted brother.
42. "Titanic" (1997)
A phenomenon the likes of which hadn't been seen for decades, "Titanic" understandably attracts a lot of backlash today. But if you can separate yourself from the hype, the fact remains that it works, dammit. Sure, it's broad-strokes storytelling, but compare it to copycats like "Pearl Harbor" and "Australia" and you can see that James Cameron is someone who actually knows how to do this kind of old-fashioned melodrama and make it click with audiences. And he's got eleven Oscars and two billion dollars to prove it.
41. "Rocky" (1976)
We're fans of Sylvester Stallone's essential boxing flick, but the familiarity of the format which it helped define has gotten to the point now where some of its lustre has faded. The sequels became broader and more, well "Eye of the Tiger"-y, but the original still feels heartfelt: it's not subtle, but it is energetic, emotive filmmaking.


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What This Article Covers
- Using the deployment heuristic.
- Setting push or pull for deployment.
- The ways in which the push or pull deployment can be configured.
Background on the Deployment Heuristic
The deployment heuristic in SNP is one of the two ways that deployment is performed in SNP. The other method is the deployment optimizer, which is much less frequently used.
Push rules are used to calculate deployment in SNP if the ATD (Available to Deploy) quantity covers the demand. – SAP Help
This is where the distribution of deployment is determined. The Push Distribution field controls whether material is pushed or pulled.
Generally the controls are described by SAP as follows.
- Pull: Materials are distributed on the due dates specified at each demand location. Nothing is distributed to the demand location in advance of the demand date.
- Pull/Push: Supply is distributed immediately to the demand locations to cover all demand within the pull deployment horizon.
- Push by Demands: The supply chain is distributed immediately to the demand locations. – SAP Help
Pull deploys per demand, but not above demand (aside from what is necessary to meet the lot sizes). Push, attempt to move out material immediately from the sourcing facility. "Push by demands" is confusing because it is so similar to Pull. However here the Pull deployment horizon is ignored. "Push taking the safety stock horizon into account" is push but with a consideration for safety stock, which the other Push Distribution parameters do not take into account. "Push by quota arrangement" essentially allows quota arrangements to control the deployment.
However, the specific difference between Push and Push/Pull is a bit misleading. In essence, Pull/Push is Push functionality, but is performed for the pull horizon.
Essentially the Push Distribution field is highly confusing and the documentation needs to be rewritten. However, it surely will not be. I will be continuing to update this post with more detail on this field.{"error":"Not Found"}


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Chinese online retailer Alibaba is planning to open an office in Russia, and to invest part of the money raised from its public offering in the Russian market. The company has yet to make an official announcement, but sources maintain that the plans will be confirmed in mid-late August, and that the office will open after the IPO in September.
At the moment the company, one of whose shareholders is Yuri Milner of DST Global, is looking for someone to lead its Russian office. They would be expected to start by early 2015. Alibaba already invited Russian experts to join its team in 2013, to assist with analysis and planning its strategy for the Russian e-commerce market.
In July Alibaba was valued at $130 billion. It is expected to go public in September, which may well be the largest stock offering in history.
Source: RusBase.vc
Robin Munby
I'm a final year modern languages student at the University of Sheffield in the UK. I have spent the last year studying at Petrozavodsk State University in Russia and the University of Havana in Cuba. firstname.lastname@example.com
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text:
Razzies 2014: See the Full List of Nominees
Bad movies beware. Last year may be behind us but the memory of 2013's worst films lives on thanks to the Golden Raspberry Awards,. The nominees for The 34th Annual Razzies were revealed on January 15 with the "winners" to be announced March 1.
Taking the lead in this year's competition — not exactly a place of honor, mind you — is the Adam Sandler-fronted Growns Up 2. Not far behind is After Earth, Will Smith and Co's failed attempt at making sci-fi family-friendly. Both movies got a nod (with accompanying frown of disapproval) in the Worst Screen Combo category as voted on by Rotten Tomatoes readers.
Noted newcomers to this year's event are Johnny Depp and Naomi Watts as well as Jaden Smith and Selena Gomez. There are plenty of veteran Razzie noms too including Lindsay Lohan, Ashton Kutcher, and potential third Worst Actor "winner" in a row Adam Sandler.
We've got the whole list below for you to peruse. Think some entertainment flop should have made the cut? Are a few of the nominees not as bad as they seemed? Share your own suggestions in the comments below.
Worst Picture
After Earth
Grown-Ups 2
The Lone Ranger
A Madea Christmas
Movie 43
Worst Actor
Johnny Depp — The Lone Ranger
Ashton Kutcher — Jobs
Adam Sandler — Grown-Ups 2
Jaden Smith — After Earth
Sylvester Stallone — Bullet To The Head, Escape Plan, and Grudge Match
Worst Actress
Halle Berry — The Call and Movie 43
Selena Gomez — Getaway
Lindsay Lohan — The Canyons
Tyler Perry — A Madea Christmas
Naomi Watts — Diana and Movie 43
Worst Supporting Actor
Chris Brown — Battle of the Year
Larry the Cable Guy — A Madea Christmas
Taylor Lautner — Grown-Ups 2
Will Smith — After Earth
Nick Swardson — A Haunted House and Grown-Ups 2
Worst Supporting Actress
Lady Gaga — Machete Kills
Salma Hayek — Grown-Ups 2
Katherine Heigl — The Big Wedding
Kim Kardashian — Tyler Perry's Temptation
Lindsay Lohan — InAPPropriate Comedy and Scary Movie 5
Worst Screen Combo
The entire cast of Grown Ups 2
The entire cast of Movie 43
Lindsay Lohan and Charlie Sheen in Scary Movie 5
Tyler Perry and either Larry the Cable Guy or That Worn-Out Wig and Dress in A Madea Christmas
Jaden Smith and Will Smith on Planet Nepotism in After Earth
Worst Prequel, Remake, Rip-off, or Sequel
Grown Ups 2
Hangover III
The Lone Ranger
Scary Movie 5
Smurfs 2
Worst Director
Dennis Dugan — Grown Ups 2
Tyler Perry — A Madea Christmas and Temptation
M. Night Shyamalan — After Earth
The 13 people who directed Movie 43
Gore Verbinksi — The Lone Ranger
Worst Screenplay
After Earth (M. Night Shyamalan and Gary Whitta, story by Will Smith)
Grown Ups 2 (Adam Sandler, Tim Herlihy, and Fred Wolf)
The Lone Ranger (screenplay by Justin Haythe, Ted Elliott, and Terry Rossio)
A Madea Christmas (Tyler Perry)
Movie 43 (written by 19 "Screenwriters")
Source: The Razzies


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ISG reports that Playdom, one of the most dominant MySpace developers, has shuttered Overdrive and Bloodlines, two text-based role-playing games. The company will still run Mobsters, Sorority Life and World Series of Poker, but who knows for how long is MySpace keeps sinking. RockYou, the folks behind games like Gourmet Ranch, has essentially boarded up shop on MySpace in closing RockYou Pets, Speed Racing and a few more social applications.
Oddly enough, Zynga hasn't completely given up on Tom yet. According to Inside Social Games, it seems as if Zynga has only shut down Street Racing on MySpace (and Facebook), a role-playing game. At the moment, the company still dominates the MySpace Top 25 with seven games: Mafia Wars, YoVille, Zynga Poker, Vampires, Fashion Wars, Special Forces, and Friend Factory. How long these games will be around is entirely up to Zynga, but gaging the MySpace situation overall doesn't bode well for games on the platform.
[Image Credit: Don't Panic]
Are you a MySpace gamer? If so, how do you feel about the platform failing? Would you ever game elsewhere than Facebook? Sound off in the comments. Add Comment.


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Welcome to the Archived, Readonly Zimbra Collaboration forums. Heres the place where we talked about all things related to Zimbra email products. Registrations and postings are disabled here.
Be sure to visit https://www.zimbra.com/forums to start new discussions and to find the latest answers to questions being asked.
How I configure the Hotmail in Zimbra?
not yet supported. we are still debating whether to add the support since there's no officially supported way for 3rd party software to do this.
Originally Posted by rapb2003
How I configure the Hotmail in Zimbra?
Thanks you.
Forum Rules


text: GoldenBearSports.com No. 7 Bears Open Camp with Intensity Cal men's soccer began preparation for the 2014 season on Wednesday By Cal Athletics on Wed, August 13, 2014 Related Links Inside the Lair Follow @CalMensSoccer on Twitter Like Cal Men's Soccer on Facebook Follow @CalMensSoccer on Instagram By Jordan Stepp. Cal Athletic Communications BERKELEY – The No. 7 California Golden Bears men's soccer program opened camp on Wednesday with an early morning session, as the 2014 season approaches. The Bears begin preparation for the new campaign on a positive note, with a lot of familiar faces from the team that reached the 2013 NCAA Quarterfinals, but also have an injection of youth into their talented side. "Today was excellent," head coach Kevin Grimes said following training on Wednesday morning. "We've got nine new players that are all extremely talented and at some point they are going to contribute heavily to this program, whether it's this year or in the very near future. The seniors looked great, it was extremely competitive and we had a fantastic start this morning." Wednesday's early morning practice at Golden Bear Field was the culmination of a long offseason for the returning team members have been itching to get back on the field. The training session saw a familiar theme, which is the extremely strong work ethic and professional atmosphere that the team exudes. Right from the jump, the Golden Bears got after it, with a high level of competition. The blue team took the mini-game competition, with freshman defender Joshua Morton scoring 12 times over the four games of 2-v-2. "I think the team looks good, and getting back here (to Golden Bear) for training and it's good to get a start to what is hopefully a successful season," senior midfielder and co-captain Seth Casiple said. "The new group is learning and they are learning very quickly, which is positive. It's obviously nice to have experience, which we have, but we also have a lot of talent with the new guys and it is fun to see that naivety that some of the new guys have. It's a very good dynamic with this group, which is healthy and we are already starting to grow closer." Among the several new faces in Berkeley this year is sophomore defender Trevor Haberkorn. The former Furman Paladin appeared in all 18 games last year as a true freshman at center back and garnered honors as a member of the 2013 Top Drawer Soccer Freshman Best XI, was named second team All-Southern Conference and also was a member of the Southern Conference All-Freshman team. His first official practice as a Golden Bear did not disappoint. "It was awesome, very intense and it was great to finally get a practice with the coaches and the group. Everyone was really excited being out here and really getting a real session in. It's only going to get better as we continue, which I really look forward to and I consider myself very lucky to have this opportunity. We are always together as a team, and there is already great camaraderie and you couldn't ask for a better squad to go day-to-day with to work hard and hopefully do just as well or better than we did last year." Following a couple of days of work in Berkeley, Cal is headed to Southern California for some bonding and training, as well as a scrimmage against the UC Irvine Anteaters. Though the results are not paramount at this point in the preseason, UCI serves as a great early barometer for the Bears. The Anteaters, like the Bears, also fell to the Maryland Terrapins in the tournament, in the third round. The Bears then return home to host a pair of scrimmages against San Francisco (Aug. 20) and Cal Poly (Aug. 23). Once the preseason concludes, the Bears head across the country to open the 2014 season against the No. 22 North Carolina Tar Heels on Friday, Aug. 29. The Heels, and Cal's second opponent of the season, No. 11 Wake Forest, are two more teams that competed in the 2013 NCAA Tournament giving the opening matches of the season a tournament-level feel. After their cross-country jaunt to North Carolina, the Bears return home to Edwards Stadium to host their home opener on Friday, Sept. 12 against Cleveland State at 1 p.m. PT. They then appear for the first of 10 times on the Pac-12 Network on Sunday, Aug. 14 against Gonzaga. There is a new ticketing policy for the 2014 home season, as all Cal students with a valid identification card will again gain admittance for free, as will youth under the age of two and children aged 2-17 for all Friday home games, while they will be charged $5 for all non-Friday matches. Seniors (65+) will be charged $5, while all other adults will be $10 for all matches. More information on ticketing for the 2014 season is available here. RECOMMENDED STORIES < Never Out Of The Game Finish First, Last The Final Chapter > OFFICIAL ONLINE STORE < Men's Nike Gray Cal Bears Team Stripe T-Shirt $25.95 Buy Now > Cal Bears Nike Navy Blue Medium Training Duffle Bag $60.00 Buy Now > > Left Promo SHOP NOW > Right Promo MORE INFO > Bears On Pac-12 Networks Full TV Schedule Get Pac-12 Networks


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- Differential Diagnosis
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Possible Rule Outs For Cluster/migraine headache syndrome - Rule Outs
Available only to registered users.
- Suggest
- 13 possible rule outs found
- Trauma Causes
- Traumatic neuralgia, Facial
- Infectious Disorders (Specific Agent)
- Post-Herpetic Neuralgia/Face
- Infected organ, Abscesses
- Abscess, orbital
- Neoplastic Disorders
- Pheochromocytoma
- Allergic, Collagen, Auto-Immune Disorders
- Temporal/Craniotemporal arteritis
- Vegetative, Autonomic, Endocrine Disorders
- Migraine headaches/syndrome
- Glaucoma/acute angle closure/cyclic crs
- Cluster/hemicrania eye/headache variant
- Glaucoma
- Atypical facial pain syndrome
- Trigeminal neuralgia
- Vail's neuralgia/facial
- Migraine, hemiplegic type
- Synonyms
- BING-HORTON SYNDROME, CEPHALALGIA HISTAMINE, CEPHALALGIA PAROXYSMAL NOCTURNAL ORBITAL, Cephalgia Histamine, Cephalgias Histamine, Chronic Cluster Headache, Chronic cluster headache (disorder), Chronic Cluster Headaches, Ciliary neuralgia, Ciliary neuralgia (disorder), Ciliary Neuralgias, Cluster headache, Cluster headache (disorder), Cluster Headache Chronic, Cluster headache syndrome, Cluster headache syndrome (disorder), Cluster Headache Syndromes, CLUSTER HEADACHES, Cluster Headaches Chronic, ERYTHROPROSOPALGIA, Headache Chronic Cluster, HEADACHE CLUSTER, HEADACHE HISTAMINE, Headache Syndrome Cluster, Headache Syndromes Cluster, HEADACHE VASOMOTOR, Headaches Chronic Cluster, Headaches cluster, Histamine cephalgia, Histamine Cephalgias, Histamine headache, Horton, Horton Syndrome, Horton's headache, Horton's neuralgia, Hortons Syndrome, Horton's Syndrome, Migraine Neuralgic, Migraines Neuralgic, Migrainous neuralgia, Neuralgia ciliary, Neuralgia migrainous, Neuralgias Ciliary, Neuralgic Migraine, Neuralgic Migraines, Syndrome Cluster Headache, Syndrome Horton, Syndrome Horton's, Syndromes Cluster Headache, Vasomotor headache
- Definition
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- External Links Related to Cluster/migraine headache syndrome - Rule Outs
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)


text:
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For sites specifically geared towards the town of North Elba. Submitting a site based in another locality may prevent listing in the directory. Thank you for your cooperation.Areas include government agencies, local laws, taxes, and the military.
Tips for Faster Acceptance:
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- In your site description, stick to the facts and avoid hype or promotional language.
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text:
Slobodan Georgijev takes the measure of the man: ... Pavle was a man with an untainted biography, devoted to the work of the church. As Patriarch, he would travel to work on public transport shunning the luxury trappings and expensive cars that formerly came with the office. "If they drive around in such expensive cars having made a pledge to modesty," Pavle is reported to have said, "what … [Read more...]
A pious Patriarch
Editorial: Turkey's 'Mildly' Islamist Government
From today's Washington Post. Turkish journalists say that a pall of fear has fallen across their business. Editors practice self-censorship. Many journalists are believed to be among the more than 100,000 people whose phones have been tapped by the government in recent years. Some, including the chief executive of Dogan Yayin, have been swept up in a murky investigation of alleged coup … [Read more...]
Funeral Service for Patriarch Pavle
May his memory be eternal. (HT: Rocor United) [youtube]http://www.youtube.com/watch?v=2-ybeT_3ocw&feature=player_embedded[/youtube] … [Read more...]
Kasper: Anglicans not Uniates
Sandro Magister offers analysis of an interview with Cardinal Kasper in "L'Osservatore Romano" on November 15 in which the cardinal discusses Anglicans heading to Rome and the reaction of the Orthodox. In Cyprus, the news that the Catholic Church is ready to incorporate groups coming from Anglicanism also put the Orthodox on alert. Their fear is that a "Uniate" Church of the Anglican rite will … [Read more...]
A 'somber' time for Egypt's Copts
From the Times (UK): The first two months of the Coptic new year have been a somber time for Egypt's ancient Christian community. The new year fell on the inauspicious date of September 11. And a spate of attacks on this large and downtrodden community by Islamist extremists or villagers giving a religious pretext to petty quarrels have provoked accusations of officially tolerated … [Read more...]
Orthodox Worried Over 'No Crucifixes' Ruling
Update (Nov. 17): Italian Mayors Order Crucifixes Put in Classrooms in Revolt against European Court Ruling. Polish president and Greek Orthodox Church also hit out at decision against crucifixes in classrooms (Source: LifeSiteNews.com) ------- From the Zenit news service: ATHENS, Greece, NOV. 16, 2009 -- The leader of the Greek Orthodox Church is ready to convoke an extraordinary synod to … [Read more...]
Ecumenical Patriarch Bartholomew sums up visit with Greek 'diaspora' in America
Turkey, Nov. 10, 2009 Ecumenical Patriarch Bartholomew referred to the great progress made by the Greek Diaspora in statements he made upon his return from a two-week visit to the United States. Addressing the faithful in the Church of the Taxiarchs in Bosporus, the Ecumenical Patriarch stated that the progress achieved by the Greek Community, its dedication to the Mother Church and the … [Read more...]
Serbia's Patriarch Pavle (1914-2009)
BELGRADE (Reuters) - Patriarch Pavle, who headed the Serbian Orthodox Church during the breakup of Yugoslavia in the 1990s as Serbs warred with neighbors of other faiths, died on Sunday, a top church official said. Pavle, 95, died at a special apartment in Belgrade's Military Hospital where he had been treated since 2007 for various ailments, Bishop Amfilohije, the acting head of the church's … [Read more...]
Russian Orthodox launch the St. Gregory Nazianzus Foundation
Robert Moynihan, editor of the Inside the Vatican newsletter, is in Moscow visiting with Archbishop Hilarion of Volokolamsk and other church people. He reports that "the Russian Orthodox have now decided to engage with Catholics, and others, in a collaboration which can be compared to an actual alliance against the great social evils of our day, not only in Russia, but also throughout Europe and … [Read more...]
Archbishop Hilarion on Orthodox-Catholic relations
From the Moscow Patriarchate, Nov. 12, 2009: During his meeting with foreign media people on 11 November 2009, Archbishop Hilarion spoke on burning issues of inter-Christian relations. He said in particular that considerable improvements took shape in relations with the Roman Catholic Church in recent years. 'There is a regular mechanism of mutual consultations and high-level visits… We can … [Read more...]
Church of Greece rallies opposition to crucifix ban
From Malcolm Brabant reporting for the BBC in Athens: The Greek Orthodox Church is urging Christians across Europe to unite in an appeal against a ban on crucifixes in classrooms in Italy. The European Court of Human Rights in Strasbourg ruled last week that the presence of crucifixes violated a child's right to freedom of religion. Greece's Orthodox Church fears the Italian case will set … [Read more...]
Report: Greek Orthodox bishops in U.S. may take Turkish citizenship
Theodore Kalmoukos of the National Herald is reporting that "the government of Turkey seems to be willing to grant Turkish citizenship to all those hierarchs of the Ecumenical Patriarchate who serve outside of Turkey. Turkish citizenship will allow them to freely participate in all the administrative activities of the Patriarchate including the right to be candidates for the Ecumenical Throne when … [Read more...]


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Bush to Unveil New Plan for Health Care
The foundation of the president's plan rests on a tax deduction—$7,500 for individuals and $15,000 for families—for people who either purchase health insurance on the open market or receive it through their employer, the White House announced Monday, January 22. The president first spoke of his new tax plan during his weekly radio address Saturday, January 20.
Tax law has long favored corporations over individuals when it comes to purchasing health insurance. Individuals looking to purchase health insurance must do so with income that has already been taxed. Employers, meanwhile, can pay for health insurance with money that is not considered part of an employee's wages and therefore not subject to payroll taxes.
The president's plan would change that. Health insurance costs would be included as part of taxable compensation, from which the full deductible would be applied. This means employers and employees whose health plans come under the deductible would receive a tax break on the difference between the deductible and the cost of the insurance plan; those whose plans cost more than the deductible would have that portion added to their total taxable compensation, increasing payroll taxes for employer and employee alike. The employee would have the added burden of paying income tax on the increased compensation.
For example, if an employee earns $50,000 and has an individual health plan that costs $10,000, total compensation would equal $60,000. The $7,500 deductible would be applied to that total, meaning the employee and employer would face a payroll tax on $52,500. Likewise, if the health plan costs $5,000, that same employee would see his or her taxable compensation lowered to $47,500.
The Bush administration, which says 80 percent of employer-provided health insurance costs less than the deductibles, is calculating that such a tax structure would encourage employers and employees alike to purchase less expensive plans.
The White House hopes such a tax structure would encourage employers to offer health insurance with lower premiums, such as high-deductible plans with health savings accounts. (In December, Bush increased the maximum amount that can be contributed to those accounts.) The tax incentive to purchase less expensive health insurance is intended to bring down costs for employers, offer a tax saving for individuals and encourage those without insurance to purchase it.
"Our challenge is clear: We must address these rising costs, so that more Americans can afford basic health insurance," Bush said in his radio address. "And we need to do it without creating a new federal entitlement program or raising taxes."
Health policy analysts have offered differing visions on how such a policy would play out.
"This is the end of employer-based coverage as we know it," says Paul Fronstin, director for health research at the Employee Benefits Research Institute. "Employers looking for an excuse to get out of it. If they're tired of providing the benefit, this gives them an excuse."
Fronstin says he fears employers would prefer to give employees a wage increase equal to the deductible and then let individuals purchase health insurance in the indivdual market.
"The tax benefit is the same whether you get it from your employer or buy it on your own," he says of the Bush proposal.
The result, he predicts, is that if given the option to take the money and purchase insurance on their own, healthy individuals would find affordable coverage in the individual market (or forgo it altogether). Meanwhile, sicker employees would purchase through their employer at higher rates. Fronstin calls this the "death spiral," but others think that is unlikely to happen.
More likely, says Paul Ginsburg, the president of the Center for Studying Health System Change, employers will retain coverage.
"The incentive to provide coverage is still there," he says, because the tax deduction could lower the amount of income subject to the 7.5 percent payroll tax employers and employees each pay. Employers would simply offer more low-cost alternatives or eliminate high-cost coverage altogether. This would encourage high or medium deductibles or more restricted networks.
"There are lots of different ways to lower the premium," Ginsburg says. "This would remove the undesirable incentive to make plans more elaborate."
How employees react to the tax incentive remains to be seen, says Paul Dennett, vice president for health care policy at the American Benefits Council.
"The real question employers will be keenly interested in is, 'Will my employees respond by shifting to lower-cost coverage to eliminate tax exposure or will they want to continue to have higher-cost heath benefits and look to employer for higher wages?'
"Generally, people tend to highly value health insurance coverage, but in the past that's because there's been no tax consequence," Dennett says.
The idea to set a limit on how much of health care costs can be tax free has been around since the Nixon administration and was reintroduced, with overwhelming opposition from unions and businesses, in 1986 by President Reagan. Bush's proposal offers something new—not simply a limit, but a deductible and in essence a tax break as well.
The president has said he prefers to make tax changes and to help fund state initiatives rather than broaden government health care programs. But whether he gets to do either will depend largely on the Democrat-controlled Congress.
"At this point in his presidency, when he has ignored the issue in the first six years, to put out a proposal that doesn't excite conservatives and looks like a half a loaf to Democrats is not likely to cause consensus," says health care author-consultant Michael Millenson, who added that the proposal would be taken more seriously if it were part of a larger reform package to tackle skyrocketing health care costs and the high number of uninsured. "Whether or not it's a good idea, he doesn't have the political capital to do anything about it."


text:
More New and Used
from Private Sellers
Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
Single-Word Usage, Cognitive Development, and the Beginnings of Combinatorial Speech: A study of ten English-speaking children
ISBN13:by Maris Monitz Rodgon
Cambridge University Press
Questions About This Book?
What version or edition is this?
This is the 1st edition with a publication date of 8/27/2009.
What is included with this book?
- The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any CDs, lab manuals, study guides, etc.
Previous investigators have believed that there is a 'holophrastic period' during the normal course of language acquisition, i.e. a period in which a child uses a single-word utterance to express something similar to the meaning which adults convey through the use of a relation, such as Fillmore's case relations, which involve more than one word. Some investigators have even attributed to the holophrase the meaning conveyed by an entire adult sentence. Previous studies have also provided evidence that from the onset of the holophrastic period, at about the age of twelve months, until the appearance of combinatorial speech, at about the age of eighteen months, the use of holophrases undergoes considerable development. This research therefore has three major goals; To document the usage of holophrastic or relational single-word speech, to demonstrate continuity in three linguistic relations from the end of the holophrastic period into the beginnings of the combinatorial period and to provide some insight into the relationship between linguistic and cognitive abilities at the end of the holophrastic period, which, of course, coincides with the end of Piaget's sensory-motor period.
Table of Contents
|Earlier work on the origins of language
|The present research as it relates to earlier work
|Design and procedures for the present study
|The patterns of psycholinguistic and sensory-motor abilities
|Toward a theory of single-word usage
|Table of Contents provided by Publisher. All Rights Reserved.


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Hi, figured i'd finally de-lurk. So i've been using a recumbent workout machine in my bedroom for a few years, but I recently moved and discovered my new place has a ton of nice bike trails around it. Basically looking for leisure riding, not interested in doing massive megarides, it's more about using the bike as a secondary source of exercise (primary will probably remain the recumbent machine). So... I took the plunge and got a new bike. Based on a recommendation from the LBS, I got a Worksman Cycle cruiser. Ordered directly with Worksman through the LBS, not one of those ripoff "Big And Tall Bikes" sites that tries to charge you $2000 for a $600 bike. So far I like it, but i've replaced the standard swept-back cruiser bars with (of all things) BMX-style uprights. So... some general Worksman observations:
* Holy crap is the bike heavy. I'd guess it weighs about twice as much as the Surly my friend has.
* But the upside of the bike being heavy is I think it can take a direct tank shell and still survive. I've completely eaten it twice, once from a stealth pothole, and once from a nasty skid in the rain, and the bike is basically untouched. All I had to do was get the fenders re-centered (doable by hand).
* The 3-speed Nexus gear inside the rear hub is a mixed bag. Plus? No derailleur. Minus? Noisier. Plus? 2nd gear is essentially direct drive just like a fixie. Minus? 1st and 3rd really aren't *that* far off from 2nd.
* The wheels are really, really strange. The call them "clincher" rims, and the tires are massive, almost like the wheels came off an old moped or something.
* This thing would probably suck for extended rides, but as an "urban assault vehicle" it works really well.
*If you're in the Boston area and looking for a friendly bike shop that is Clydesdale-friendly, I 100% reccomend Ferris Wheels down in Jamaica Plain. Every single person there has been nothing but supportive, friendly, and encouraging.
I know the whole Worksman / cruiser thing is kind of different from the road / mountain bikes most people here are looking for, but in any case a pic of my bike is here:
In any case, just wanted to say "hey." After ~ 100 miles I'm liking the bike. I think with perfect hindsight I might have gone with a Surly instead, but i'm happy with this bike so far and plan to ride it into the ground, knowing that i'll break long before the bike does.


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Sunshine Cleaning is known snidely in some quarters as "Sundance Sunshine 2," a reference to the fact that, like Little Miss Sunshine, it debuted at Sundance (in 2008), mixes drama without offbeat comedy and is about a dysfunctional family from Albuquerque. Oh yes, it also features Alan Arkin as a crotchety grandpa.
But, really, for most of its length, Sunshine Cleaning is no clone. Written by Megan Holley and directed on a tight budget by tough-minded New Zealander Christine Jeffs (Sylvia, Rain), it offers an authentically melancholy view of America as a place where some people die lonely and often violently, their lives reduced to little more than the bloody mess they make when they go.
Two wonderfully emotionally alert actresses at their best, Amy Adams and Emily Blunt, play working-class sisters Rose and Norah, whose job it is to clean up that mess. As they go about their business, consoling a surviving spouse or finding a kitten left behind, the film achieves stretches of pathos. And the details of how they do their work are surprisingly engrossing, especially as Rose strikes up a friendship with Winston (Clifton Collins Jr.), the droll, one-armed owner of a cleaning-supplies shop. And the attraction that Norah begins to feel for another women (Mary Lynn Rajskub) also leads to several good scenes.
But just when the movie needs to go deeper and really test Rose and Norah's resolve, it wraps up too easily with an upbeat ending that seems unearned and unbelievable. Grade: B
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text:
Rank: 11 (tie)
Firm: Tudor
Investment Corporation Headquarters: Greenwich, Ct.
$200 million While Tudor
Investment Company's Tensor Fund returned a dismal -10.29% net of fees in 2011,
the firm's $8 billion flagship BVI Global Fund, managed by Jones himself,
produced a respectable 2.12% net return. Tudor is offering a new class of
shares in the fund that will allow investors to choose between fees of 2.75%
and 27% or the 4% and 23% he currently charges. The noted outdoorsman
apparently has developed a second hobby: updated tax rolls in Greenwich, Ct.,
revealed 16 cars registered in Jones' name in February.
Photo: Amanda Gordon/Bloomberg via Getty Images


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Whitaker Farm Fresh Market is reminiscent of an old-fashioned country store. It is a family owned and operated business striving to combine personal service and quality at an affordable price. Our store can be divided into three product lines: Local Foods, Organic Foods, and Bulk Foods.
Local Foods
There are numerous benefits of eating local food. Above all, the food is fresh. Food that has traveled hundreds or even thousands of miles cannot possibly be considered fresh. And when it is grown in healthy, mineral-rich soil and picked at the peak of ripeness, local food offers numerous nutritional advantages. In addition, buying local food supports local farmers. There are numerous personal and social benefits associated with supporting local growers who care for the soil and follow responsible production practices. Stop in and get some local beef, pork, chicken, dairy products, kim chi, popcorn, honey, and more.
Organic Foods
Mass production has gone far beyond automobiles and furniture! The old family farm has been widely replaced by large corporations that mass produce the world's food supply. The health repercussions of the chemicals and genetically modified seeds that make this possible are only beginning. We offer you over 30 products that are GMO- and chemical-free.
Bulk Foods
Like to cook from scratch? We have everything you need for your favorite recipes. Additionally, our bulk food selection includes some fun things like candy, trail mix, and snacks! Many of our customers have also noticed that some of our dried fruit is extremely fresh; stop in today for the freshest raisins in town!


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It's been one week since we launched the Lion Brand notebook and it's been a real thrill reading all the comments. I especially liked the one from Laura, who wrote from Argentina. She said, "even though your yarns are not available in Argentina, I just want to thank you for all the interest(ing) things I find at your place. . . I can't buy your products, but I love to see the patterns and all the tips you give us."
You may wonder why I was so pleased at a comment from someone who can't even buy our yarn. It's because when Lion Brand can encourage someone to knit and crochet, I believe we have done something good. I am thankful for the fact that I am part of a business that helps make peoples' lives better. Yarn provides people with a way to de-stress, a way to express themselves creatively with color and fiber, a way to share something handmade with others and so much more.
You may even be surprised to know that I work with my competitors (I like to refer to them as my friendly competitors) several times a year to come up with ways to promote and encourage crafting with yarn. I'm chairman of an organization called the Craft Yarn Council which, among other things, organizes the annual Knit Out, now held at the Mall of America in February.
Loving my work means loving the business I'm in as well as believing in our products.
Posted in Lion Staff | 5 Comments » Comments
This is our first Q & A post so we'd like to share how the questions come to us. Lion Brand customer service associates answer questions by phone and email. We respond to over 12,000 email questions each month. This Q & A feature is culled from the most commonly asked questions. If you would like to submit a question, kindly do so in any of the following ways, rather than through this blog:
You may email it to firstname.lastname@example.com. For questions about an order you already placed, you may email or call 800-661-7551. If you need phone support to help you work through a pattern, you may call 800-705-8636. Keep in mind that these phone numbers are available only weekdays from 9:00 a.m. to 5:00 p.m. Eastern Standard Time.
Q – I'm trying to find an crochet afghan in Vanna's Choice that is easy enough for someone who knows simple stitch patterns.
A – The best way to find just what you are looking for is to use our Pattern Finder. With over 1,900 patterns to choose from (and growing daily), this great tool will save you lots of time. We used the pull-down menus to select "crochet" as the craft, "Vanna's Choice" for the yarn, "easy" for the skill level and "afghans/throws/blankets" for the item type. The Pattern Finder located 14 afghans for you.
Try this with any requirement you have. Whether you looking for a baby blanket in Babysoft, a sweater in Wool-Ease or a scarf in Wool-Ease Thick & Quick, the Pattern Finder is the shortest route to get to those patterns.
If you want to fill in the search bar instead of using the drop-down menus, you can enter words describing what you want. The results will not be as accurate as they are when you use the drop-down menus, but if you prefer this method, use what works for you!
Give the Pattern Finder a try and let us know how it works or if you have any questions about it.
Posted in Tips & How To | 5 Comments » Comments
Our customer gallery is a spot on our site where you can see what other people are working on or upload your own images. Here's one we loved, submitted by Jessica Basciano, of a picture that she takes annually of her children wearing sweaters knit by her grandmother. Here's what she says: "My 84 year old Grandmother, Betty Harris, has made an annual event of making sweaters for 4 of her Great-Grandchildren, Cate, Julia, Colin & Aaron, and having their photo taken. She always uses Lion Brand Yarn and is thrilled to see her work displayed on your web-site. Thank You!
Posted in Community, Knitting | Comments Off on Sharing Your Handiwork Pictures Online Comments


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Deep-water Gulf of Mexico in comeback mode
Oil giants including BP are gearing up in a big way three years after explosion and enormous spillOctober 18, 2013
Photo: handout
Polluted by crude, crises and fears of ceaseless political entanglements, the Gulf of Mexico looked endangered as an oil hub after BP's massive 86-day spill three years ago.
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NEW DELHI: Power and steel plants of state-run companies like NTPC and Steel Authority of India Ltd that are ready for operations and are being set up in coal-starved states will get priority in coal block allocations.
The government will rate power and steel companies on a scale of 30 points based on criteria like their financials, past record in developing a coal block and proximity of the end use project to the coal block. Firms scoring the maximum points will bag the blocks.


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Headers And A Y-Pipe For LS1 F-CarsWritten on December 31, 2003 Best Bolt-Ons for Your Late-Model Musclecar
In our special Late Model Bolt-Ons section of the Feb. '03 issue, we showed how the addition of a set of Hooker headers and a high-flow off-road Y-pipe added 16.4 hp and 13.7 lb-ft to the rear tires of a 2001 Camaro SS test car. Though the Hooker catalog says its PN 2253-1HKR headers only fit '98-'99 LS1 F-cars, the guys at Morgan Motorsports found some simple tricks to make them work on later cars as well. Check it out.
More Photos From This Article View Slideshow
If your LS1 F-body is a 2000, you'll need a '98-'99 Z28 lower exhaust gas recirculation (EGR) tube. It's available as PN 12556643 (retail price $99.24) from your local GM dealer and bolts right in place. On '01 and '02 models, you'll have to make a simple EGR blockoff plate and bolt it to the EGR port on the passenger-side header because GM eliminated the EGR system on LS1 F-cars after the 2000 model year.The electric air-injection pump on all '98-'02 LS1 F-cars is located behind the driver-side headlight unit. It pumps air through a series of 3/4-inch rubber hoses and steel tubes to the exhaust manifolds/headers to aid catalytic converter light-off. Though the Hooker headers are ready to accept stock '98-'99 air injection tubes and fittings, later 2000-'02 tubes don't line up. To remedy the situation, place each steel tube in a vice, heat it, then twist it roughly 90 degrees. Presto, they're now ready to bridge the gap between the air-injection fittings on the headers and the feed hoses poking out from the firewall. Here a propane torch heats the tube prior to bending.Once the tube is cherry red, all you need is a pair of heat-resistant gloves and a firm grasp to set things right. Try to do this in one take to avoid excess metal fatigue and splitting. Compare the orientation of the air tube inlet in this photo to the last photo, and you'll see the result of the 90-degree twist. Remember, you have to do both tubes.Here's a modified air pump tube being bolted into position. Though the tubes deform a little and may look a bit ugly after twisting, the stock heat socks cover the scars, and Morgan Motorsports says emissions are unaffected.


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Digital Writing Month Focuses on New Forms of Writing
Marylhurst sponsors month-long challenge to encourage and inspire writers.
Whether you text and blog or write novels, you're a writer. And the digital space brings many new opportunities to convey meaning. Those are just two of the lessons Marylhurst University hopes to share during Digital Writing Month, the online writing challenge it is sponsoring throughout November to shine a spotlight on the nature and practice of digital writing.
The event is a challenge for participants, and also serves as a massive open online course and a research tool for those interested in the practice of digital writing. Participants in Digital Writing Month (www.digiwrimo.com) are encouraged to write 50,000 words throughout November. They'll have a lot of help along the way from event facilitators, who will post exercises and ideas to spur new writing habits and inspire fresh thinking about a range of projects, from blogs to poems to text and image combinations. On November 17, participants will have the opportunity to gather on the Marylhurst campus for "The Night of Writing Digitally," where they can meet their fellow writers and cheer each other on in their projects.
"Digital writing can affect the way people write for print and the way they read. It can even affect the author's voice and how the audience responds to the text," said Jesse Stommel, director of Marylhurst's English and digital humanities online program. "Digital Writing Month will allow participants to really delve into what makes writing in an online environment different. And they'll get some excellent writing practice that encourages community and collaboration."
The month-long online event is sponsored by Marylhurst's English and digital humanities online program, which is launching a new bachelor's degree in January 2013 that integrates writing, literary studies and the humanities in a digital environment; most of the degree will be earned through online courses, with only periodic trips to the Marylhurst campus. The writing challenge is inspired by National Novel Writing Month, a similar event that encourages participants to write novels of 50,000 words during November.
Digital Writing Month will bring together a diverse audience – from local high school and college students to teachers and writers from around the country and world – to participate in digital writing projects. Digital writing includes all text written, transferred and published electronically, from email and text messages to blog and Twitter posts and Facebook updates. With digital writing, it's not just the words that matter; the images, formats and channels writers choose all provide important context in conveying the message.
"Digital writing is a core practice for the emerging field of digital humanities. But it's also mostly misunderstood," added Stommel. "We can no longer write the way we used to write, because the writing itself isn't the same as it used to be. When people join us in our experiment with digital writing, I think they'll discover that writing has evolved in surprising ways."
To learn more, visit the Digital Writing Month website at www.digiwrimo.com or follow @DigitalEnglish and @DigiWriMo on Twitter. For more information about Marylhurst's English and digital humanities online program, visit www.marylhurst.edu/digitalenglish.
About Marylhurst University
Marylhurst University, a private liberal arts university 10 miles south of Portland, Ore., on Highway 43, is regionally accredited and nationally recognized for innovation and academic excellence in serving adult learners. Founded in 1893, Oregon's oldest Catholic university serves nearly 1,800 multigenerational students of all faiths and backgrounds. Marylhurst offers more than 50 undergraduate and graduate degrees and professional certificate programs on campus and online, all of which integrate the liberal arts with professional studies and prepare graduates to be ethical leaders who think critically and creatively.


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Research Profile: David Kaye
Research Profile: David Kaye
Moving Theater in New Directions: Theater for the 21st Century
While theater may be one of our most ancient forms of human artistic expression, David Kaye's latest project was anything but old-fashioned. Kaye teamed up with N.B. Aldrich and the University of Maine's Intermedia MFA program to present "eStranged," a 21st-century response to Albert Camus's "The Stranger."
Originally published in 1942, the novel explores themes of existential philosophy, societal systems of control, and alienation. "We are arguing that the systems of control that Camus discussed have shifted to the Internet," said Kaye, co-author and co-director.
But what made this already fascinating topic truly revolutionary was the way in which the play was presented. Two separate audiences viewed two groups of actors via a live feed. This new approach, known as a "telematic performance," is a form that allows artists to overcome traditional geographical limitations through the use of communications technology. By viewing projections of the actors on monitors, the audiences were able to see a work that formed a cohesive whole.
Fewer than ten telematic performances have been displayed internationally, and Kaye's project was in development for two years. Rehearsal proved to be both exciting and challenging for this production, which debuted on November 20, 2013. Because technology was essential to the storytelling, the necessary equipment needed to be set-up and synched before the actors and crew could begin work. However, the realization of a new form of theater that can link a human audience across a geographic space is a goal that Kaye and his colleagues have been thrilled to pursue.
Kaye's other projects include directing both inside and outside the university. In a typical year, Kaye will direct one play for UNH and two works for separate production companies. Recently, he worked with Maine-based actress and author Susan Poulin to direct her one-woman show, "I Married An Alien." He presents regularly at national conferences, sharing research on a broad range of topics including acting, directing, applied theater, and social justice. Two years ago, Kaye co-developed and directed "Bloodshed, Deliverance, Miracles, Good Food!" which had its premiere at the Theatronetto Festival in Tel Aviv before going on to performances in Haifa and New York City. The piece was created while he was in Israel as a Fulbright Scholar. He is currently developing a new play, "How I Brought Peace to the Middle East," based on his Fulbright experience.
Kaye's work is far from limited to the "traditional" realm of performance art and the humanities. Applied theater, which Kaye describes as "acting for non-actors," utilizes theater models and pedagogy (the science and art of education) to improve communication, address social issues, resolve conflict, and encourage professional and community development. He utilizes the work of Augusto Boal, who described these types of exercises as "rehearsal for the future." In collaboration with UNH's Carsey Institute, NH Listens (a UNH-based facilitation service), Kaye has organized an applied theater project to help develop the skills of people who facilitate public meetings. In June 2013, Kay and his theatre group, Powerplay Interactive Development, helped facilitation experts from UNH Cooperative Extension use this approach to practice new strategies for navigating difficult or contentious community conversations (pictured at right).
Currently, Kaye is working with UNH's ADVANCE program to tackle the topic of gender bias in the fields of science, technology, engineering, and mathematics (STEM). The audiences for these performances are made up of university professors in STEM, administrators, and other educators from departments across UNH. Each scenario is staged with actors and begins with a pre-planned scene about fifteen minutes in length. This sketch models the behavior of a university hiring committee and ultimately results in an unsatisfactory outcome. The action is paused at various points, and the audience is encouraged to ask questions of the involved characters. After a discussion, audience members have the opportunity to "rewrite" the scenario, either telling the actors how to perform or, if they feel inclined, jumping into the performance to participate.
Kaye explained that this activity helps participants articulate how gender bias functions in hiring situations. By witnessing a physical display of the action, the audience is able to break down the behavior. Kaye has seen professors become captivated by the opportunity provided by this outlet, which accommodates a trial of various techniques in a setting with peers.
Kaye's work breaks new artistic ground while also providing rich opportunities for the University community. Whether he is combining computers and Camus or facilitating a dialogue on the social issues that define the modern human experience, Kaye's passion and expertise is a great resource for the world of theater and UNH.
By Paige Belisle
This story first appeared on the UNH Research website


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Jan 7, 14 •
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I've been wondering about the impact of France's "millionaires tax." At first a 75% tax on individual incomes above €1 million ($1.37 million), the proposal had to be tweaked when France's Constitutional Council said it was...... [read more]
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More New and Used
from Private Sellers
Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
Fear of Food : A History of Why We Worry about What We Eat
ISBN13:by Levenstein, Harvey A.
Questions About This Book?
What version or edition is this?
This is the 1st edition with a publication date of 4/1/2012.
What is included with this book?
- The Used copy of this book is not guaranteed to include any supplemental materials. Typically, only the book itself is included.
There may be no greater source of anxiety for Americans today than the question of what to eat and drink. Are eggs the perfect protein, or are they cholesterol bombs? Is red wine good for my heart or bad for my liver? Will pesticides, additives, and processed foods kill me? Here with some very rare and very welcome advice is food historian Harvey Levenstein: Stop worrying! In Fear of FoodLevenstein reveals the people and interests who have created and exploited these worries, causing an extraordinary number of Americans to allow fear to trump pleasure in dictating their food choices. He tells of the prominent scientists who first warned about deadly germs and poisons in foods, and their successors who charged that processing foods robs them of life-giving vitamins and minerals. These include Nobel Prizewinner Eli Metchnikoff, who advised that yogurt would enable people to live to be 140 by killing the life-threatening germs in their intestines, and Elmer McCollum, the "discoverer" of vitamins, who tailored his warnings about vitamin deficiencies to suit the food producers who funded him. Levenstein also highlights how large food companies have taken advantage of these concerns by marketing their products to combat the fear of the moment. Such examples include the co-opting of the "natural foods" movement, which grew out of the belief that inhabitants of a remote Himalayan Shangri-la enjoyed remarkable health and longevity by avoiding the very kinds of processed food these corporations produced, and the physiologist Ancel Keys, originator of the Mediterranean Diet, who provided the basis for a powerful coalition of scientists, doctors, food producers, and others to convince Americans that high-fat foods were deadly. In Fear of Food,Levenstein offers a much-needed voice of reason; he expertly questions these stories of constantly changing advice to reveal that there are no hard-and-fast facts when it comes to eating. With this book, he hopes to free us from the fears that cloud so many of our food choices and allow us to finally rediscover the joys of eating something just because it tastes good.
Table of Contents
|p. vii
|p. 1
|p. 5
|Milk: "The Most Valuable and Dangerous Food"
|p. 17
|Autointoxication and Its Discontents
|p. 27
|Bacteria and Beef
|p. 43
|Lucrezia Borgias in the Kitchen?
|p. 61
|Vitamania and Its Deficiencies
|p. 79
|"Hidden Hunger" Stalks the Land
|p. 95
|Natural Foods in Shangri-la
|p. 107
|p. 125
|Creating a National Eating Disorder
|p. 139
|p. 161
|Abbreviations for Frequently Cited Sources
|p. 165
|p. 167
|p. 209
|Table of Contents provided by Ingram. All Rights Reserved.


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Paper and Envelope Size, Weight and Style Charts
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Use these exclusive paper and envelope size and weight charts and other helpful paper and envelope information to help you get the most out of your shopping experience with The Paper Mill Store Wisconsin based online shopping paper warehouse.
We hope you find this information helpful and please feel free to contact us with any questions you might have regarding any paper or envelope subject.


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Commercial & Residential Electrical Services
As your electrical concierge, At Your Service Electric and Ridgefield Electric have been providing outstanding electrical service to customers in Fairfield County, Connecticut and Westchester County, New York for nearly 30 years. We cater to both residential and commercial electrical work.
Our Electricians Specialize in:
- Installations
- Repairs
- Maintenance
- Inspections
We strive to ensure that our service exceeds our customers' expectations. No matter how small or large the job, you are very important to us! That's the reason why we are considered one of the most reliable independent service providers in the area. We will schedule the needed work at your convenience, and you can count on our highly-trained, uniformed electricians to be on time.
To save our customers time and money, we use upfront pricing. We also stock our trucks with thousands of the highest quality parts, so no time is wasted picking up supplies for your job (unless the situation is unusual). Emergency service is available 24 hours a day, and our phones are always answered by a live person– you will never talk to a machine.
At Your Service Electric and Ridgefield Electric are continually researching the latest electrical products & service offerings. If you have questions about our electrical services or would like to schedule an appointment, please contact us. We are dedicated to your satisfaction.
We hope you'll make us your resource for all things electrical!


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ATI announced their new architecture the Evergreen family of video cards in September of last year aboard the U.S.S. Hornet, a World War II-era aircraft carrier. The Evergreen family consists of many variants including the Cypress (5870, 5850), the Juniper (5770, 5750), the Hemlock (5970), the Redwood (5670) and the Cedar (55 series and 5450). Today marks the release of the Redwood version of their new architecture, the Radeon HD 5670.
XFX is a manufacturer of video cards based upon both NVIDIA and ATI chip. For the last year or so XFX has used ATI chips on their cards which is a wise choice as NVIDIA based cards are not competitive at the moment feature or performance wise. They have already released cards based upon every member of the Evergreen family and todays review is on the Redwood card, the RADEON HD 5670. This is the reference clocked version, with XFX normally releasing variants with higher clock speeds later.


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|Article Authors:
|Tobias Manigold; Eui-Cheol Shin; Eishiro Mizukoshi; Kathleen Mihalik; Krishna K Murthy; Charles M Rice; Ciriaco A Piccirillo; Barbara Rehermann
|Article Title:
|Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C.
|Reference Detail
|Reference ID:
|Hepatitis C virus (HCV) poses a global health problem because it readily establishes persistent infection and a vaccine is not available. CD4(+)CD25(+) T cells have been implicated in HCV persistence because their frequency is increased in the blood of HCV-infected patients and their in vitro depletion results in increased IFN-gamma production by HCV-specific T cells. Studying a well-characterized cohort of 16 chimpanzees, the sole animal model for HCV infection, we here demonstrate that the frequency of Foxp3(+)CD4(+)CD25(+) regulatory T cells (T(Regs)) and the extent of suppression was as high in spontaneously HCV-recovered chimpanzees as in persistently HCV-infected chimpanzees. Foxp3(+)CD4(+)CD25(+) T(Regs) suppressed IFN-gamma production, expansion, and activation-induced cell death of HCV-specific T cells after recovery from HCV infection and in persistent HCV infection. Thus, T(Reg) cells control HCV-specific T cells not only in persistent infection but also after recovery, where they may regulate memory T-cell responses by controlling their activation and preventing apoptosis. However, Foxp3(+)CD4(+)CD25(+) T(Reg) cells of both HCV-recovered and HCV-infected chimpanzees differed from Foxp3(+)CD4(+)CD25(+)T(Reg) cells of HCV-naive chimpanzees in increased IL-2 responsiveness and lower T-cell receptor excision circle content, implying a history of in vivo proliferation. This result suggests that HCV infection alters the population of Foxp3(+)CD4(+)CD25(+) T(Reg) cells.
|Immunology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
|Reference Type:
|PubMed ID:
|Journal Volume:
|Article Pages:
|Journal ISSN:
|Article Chemical List:
|Forkhead Transcription Factors;Interferon-gamma
|Article MeSH List:
|Animals; Apoptosis; Forkhead Transcription Factors(immunology; physiology); Hepacivirus(immunology); Hepatitis C(immunology); Immunologic Memory; Interferon-gamma; Lymphocyte Activation; Pan troglodytes; T-Cell Antigen Receptor Specificity; T-Lymphocytes(immunology); T-Lymphocytes, Regulatory(immunology; physiology)
|Curation Last Updated:
|2015-07-24 20:11:21


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Criminal Law
Criminal Law Questions? Ask a Criminal Lawyer.
Good evening Gabriel,I'm Doug, and I'm very sorry to hear of your situation. My goal is to provide you with excellent service today.Yes, absolutely, under NY law, what your ex is threatening constitutes criminal Coercion. Here is the law:N.Y. PEN. LAW § 135.60 Coercion in the second degree.A person is guilty of coercion in the second degree when he or she compels or induces a person to engage in conduct which the latter has a legal right to abstain from engaging in, or to abstain from engaging in conduct in which he or she has a legal right to engage, or compels or induces a person to join a group, organization or criminal enterprise which such latter person has a right to abstain from joining, by means of instilling in him or her a fear that, if the demand is not complied with, the actor or another will: 1. Cause physical injury to a person; or 2. Cause damage to property; or 3. Engage in other conduct constituting a crime; or 4. Accuse some person of a crime or cause criminal charges to be instituted against him or her; or 5. Expose a secret or publicize an asserted fact, whether true or false, tending to subject some person to hatred, contempt or ridicule; or 6. Cause a strike, boycott or other collective labor group action injurious to some person's business; except that such a threat shall not be deemed coercive when the act or omission compelled is for the benefit of the group in whose interest the actor purports to act; or 7. Testify or provide information or withhold testimony or information with respect to another's legal claim or defense; or 8. Use or abuse his or her position as a public servant by performing some act within or related to his or her official duties, or by failing or refusing to perform an official duty, in such manner as to affect some person adversely; or 9. Perform any other act which would not in itself materially benefit the actor but which is calculated to harm another person materially with respect to his or her health, safety, business, calling, career, financial condition, reputation or personal relationships. Coercion in the second degree is a class A misdemeanor. You may reply back to me again, using the Reply to Expert link, if you have additional questions.I wish you the best in your future,Doug
How do I deal with the police officers who do not feel that there is enough to arrest her at this time?
DISCLAIMER: Answers from Experts on JustAnswer are not substitutes for the advice of an attorney. JustAnswer is a public forum and questions and responses are not private or confidential or protected by the attorney-client privilege. The Expert above is not your attorney, and the response above is not legal advice. You should not read this response to propose specific action or address specific circumstances, but only to give you a sense of general principles of law that might affect the situation you describe. Application of these general principles to particular circumstances must be done by a lawyer who has spoken with you in confidence, learned all relevant information, and explored various options. Before acting on these general principles, you should hire a lawyer licensed to practice law in the jurisdiction to which your question pertains.
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