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Sunset at the Palms Resort and Spa
What to expect (based on 3116 reviews):
5 most recent TripAdvisor reviews:
Relaxing vacation
Reviewed by GlobeTrotting790951() on Feb 10, 2019
Overall it is a great and very relaxing resort. I'd call it all inclusive for people who normally don't do all inclusive. Number of rooms is limited, rooms are not sharing walls with each other, and surrounded by well manicured jungle. We've asked for the room in quiet location away from the road and the restaurant/pool, and were given one in 700 section. It was very quiet at night. Room was comfortable, had adequate storage and great shower. Water pressure was always good. Temperature was sometimes hot, sometimes warm, but always comfortable to take a shower. Best things about this resort are: beach, service, and food. All three were outstanding. Security at the resort and the beach was also very good. Restaurant did excellent job preparing traditional Jamaican dishes for breakfast and dinner in addition to standard resort "cousine". If you never tried this before, use this opportunity. You will not be disappointed. Beach grill is also excellent.
Great first stay...will likely return.
Reviewed by goddess of r(somewhere anonymous) on Feb 09, 2019
We stayed at this resort from Jan. 28 - Feb. 4, 2019. I'd been reading reviews for months, so I wasn't surprised by the features some people seem disappointed about (of course there's no pleasing some people). I highly recommend future visitors read many reviews so they know what to expect. Of course one's degree of satisfaction depends not only on expectations but one's values. On both counts, this resort delivered for us. As Canadian cottagers, we found the rooms and grounds splendid. The photos don't really do it justice. It's a magical place. And a nature-lover/birdwatcher's paradise. If you visit, don't forget to say hello to Cheech the lizard who hangs out on the lightpost by the smoking area nightly. Service was excellent. Was every detail of the resort perfect? No. But we felt we received good value. We're grateful to ALL the staff for their hard work and friendly, helpful attitude. They do an amazing job of making everyone feel welcome, and it's clear how much love goes into every aspect of the experience. We hope to see you again! One general comment for travelers (not related to the resort), I found the drive from Montego Bay to Negril stressful - narrow, winding cliff-side roads and traffic chaos (compared to what I'm used to). So, if you have fragile nerves be prepared for that.
Perfect Destination
Reviewed by Gary C(Salem, Oregon) on Feb 09, 2019
We just returned from our two week stay at SATP. This was our third stay at this location in as many years. We traveled with another couple who were there for their second time. All of us had a wonderful stay and would not hesitate to return. The Staff: First of all a tip of the hat to Stacey. What a wonderful way to start out the day. She is a gem. The same goes for Claudette. Both in the morning and at lunch, Claudette is there with her wonderful smile. Both of these ladies are the best. When we returned we were looking forward to seeing Vanessa again. We were not disappointed on our first night back. She is not only attentive and helpful, but a joy to be around. And then there is Duane. We met Duane for the first time last year and were thrilled to see him again this year. He just sparkled with his smile and laugh. He was so helpful and always there to make sure we had what we needed. And then there is Craig. From our first stay Craig has been a favorite and this year was no exception. All of the staff go above and beyond. There was also a young lady daily at the grill on the beach but I did not get her name. She was always so happy and friendly with a genuine smile and went out of her way to make sure we got what we wanted. We often ate our lunches there because of her. The food was again outstanding. We all truly felt there was something that put it above what we rememberd from previous visits. The food and selection were always great before, but there was just something this year that made it stand out. The prime rib on Italian night was the best I have had in years. The addition of the BBQ night at the beach was truly outstanding. The additional work all of the staff went to in order to make this happen was evident and it was wonderful. The resort and overall facilities were again clean and extremely well maintained. We had an issue when we first arrived with our air conditioner. We mentioned it and there was someone at our cabin within minutes to make sure it was taken care of, and it was. The beach was pristine. You walk either way on the beach and look as adjacent resorts to see beach debris all along the edge of the water. Not so at SATP. Everything is clean and freshly manicured in the morning and throughout the day. The same was true about the grounds at the resort. We were so happy so see Clinton again. Bottom line is, we are already talking about our return trip next year. We arrived towards the end of January 2019 and left February 7th.
Reviewed by 144sonya(Mandeville, Jamaica) on Feb 06, 2019
Had a very relaxing weekend. A quiet getaway for all workaholics. The beach is absolutely breathtaking and inviting. I would visit the Palms every month if I was able to. The staff is friendly and nice.
Great Vacation
Reviewed by jamaikafun(London, On) on Feb 06, 2019
Celebrating a retirement. We give this resort a 5. Everything was Irie, very nice. Great food, service, ..... We had a great time. Everyone was polite and wanted us to experience a wonderful vacation. All you read on trip reports are true. We have no complaints. Our treehouse was lovely, but I do have one suggestion for better lighting at the bottom of the stairs room 714, seemed to be very poorly lighted unlike the other treehouses, and I experienced a few near misses. We loved the gardens, the beautiful birds, the tree frogs at night and the Jamaica sun and blue sky and water. The beach was the best on the bay. The craft market on the bay was also nice and had fair prices. Bring your insect cream or spray, as even though the resort is fogged, you must remember the Great Morass is just behind the resort. We enjoyed the specialty restaurants, and the main buffet. Beach grill and red flag service was wonderful. Even a superbowl party to enjoy. The resort is very clean ans well kept. Yes, this was a very nice vacation. Sunset at the Palms -thank you we had a wonderful time.
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Reggae Fashion Style
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As noun
a room, set of rooms, or building where the business of a commercial or industrial organization or of a professional person is conducted:the main office of an insurance company; a doctor's office
a room assigned to a specific person or a group of persons in a commercial or industrial organization:Her office is next to mine
a business or professional organization:He went to work in an architect's office
the staff or designated part of a staff at a commercial or industrial organization:The whole office was at his wedding
a position of duty, trust, or authority, especially in the government, a corporation, a society, or the like:She was elected twice to the office of president
employment or position as an official:to seek office
the duty, function, or part of a particular person or agency:to act in the office of adviser
(initial capital letter) an operating agency or division of certain departments of the U
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(initial capital letter) British
a major administrative unit or department of the national government:the Foreign Office
hint, signal, or warning; high sign
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the prescribed order or form for a service of the church or for devotional use
the services so prescribed
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the prayers, readings from Scripture, and psalms that must be recited every day by all who are in major orders
a ceremony or rite, especially for the dead
a service or task to be performed; assignment; chore:little domestic offices
offices, Chiefly British
the parts of a house, as the kitchen, pantry, or laundry, devoted mainly to household work
the stables, barns, cowhouses, etc
, of a farm
Older Slang
As adjective
of or relating to the Ottoman Empire
of or relating to the lands, peoples, and possessions of the Ottoman Empire
As noun, plural Ottomans
Also, Othman (for defs , )
a Turk
a Turk of the family or tribe of Osman
(lowercase) a cushioned footstool
(lowercase) a low cushioned seat without back or arms
(lowercase) a kind of divan or sofa, with or without a back
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Garden Maintenance Springfield VA - Other Classified Ads in Springfield
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China It is turning into a first world power, and not only from the economic point of view. In the world of fashion every time it is taking more importance. A year ago, Karl Lagerfeld He chose the wall of china for the parade of Fendi, y luxury stores open more and more stores in the country, seeing the passion that the Chinese feel for the most popular brands such as Chanel or Louis Vuitton.
On the occasion of the delivery of Awards Fashion Icon of the hand of Vogue China, numerous well known faces moved to Beijing. As always, the most anticipated of all, Kate Moss, that came from the hand of Jamie Hince, which seems that it has made peace. She received one of the awards of the night, and was gorgeous with a long black dress, letting one of the shoulders to the air, as a Greek tunic.
Among the guests were also other models as Milla Jovovich, with a very original oriental headdress and a dress in pastel with details of ties.
The model Jessica Stam chose the always elegant black.
Sasha Pivovarova He wore a dress in white and black with fringe details. Like mile, he decorated his head with a headdress.
Lou Doillon He wore a very spring dress of chiffon and floral print of Nina Ricci, with the front shorter than the back (good way to show off legs and shoes).
Other attendees were designers Phillip Lim, Olivier Theyskens and Rouland Mouret. Finally, the celebrity Eugenie Niarchos, that already I talk long and hard one day, wore a warm fur bolero's Giambattista Valli.


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What a start to the week, we couldn't have wished for better conditions! The best conditions this season so far! Monday was a powder day; face shots and knee-deep powder. The best thing about it was the snow was set to keep falling all week!
Some had the rest of their first aid course to finish this week, while others started their work shadowing. As Harry kept saying, the majority of the time shadowing children's lessons consisted of him picking small children up out of the deep snow as they kept disappearing.
Tuesday brought The 3 Valleys' legendary band 'Bring your Sisters' back to play for a one-off gig as they stopped playing a couple of years ago. Brad, Andy and a few of the others knew who they were and knew they were in for a treat. Everyone went down to après, and what an après it was!
This week saw Andy leave us all behind to go back to good old Blighty as he was only here for the BASI Level 1. He will be missed by us all but we will be seeing him again shortly as he tells us he'll be back in the spring. We'll see you soon Andy!
As the snow was getting deeper some of the SnowSkoolers asked if the instructors would take the groups off-piste and do some avalanche training with them. Everyone one had fun in the pow and there were smiles all round.
Friday saw the start of the Six Nations, and everyone was keen to get down to the Tsaretta to watch. We have lots of rivalry between some of the SnowSkool gang with Scots, Irish, Welsh and English all included in the group.
Last but not least we should give a special mention to Rob for making it on 'Jerry of the Day' for his amazing big air fail!!! If you haven't had chance to see the video you should definitely head on to Jerry of the Day Instagram or Facebook.


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Song Review Posted On: 19th November 2018 2967 Views
The numerous award winning singer, vocalist and writer, the C.E.O of Kream Production Hajji Haruna Mubiru has released a new single titled Wefuule Malaaya. This new love single was mastered, produced and mixed by Producer Jonah specifically for the married and cohabiting couples.
Wefuule Malaaya which translates to Role Play As A Call Girl To Your Partner is new single that educates, informs and reminds married couples that new tricks, tactics and inventions are needed to keep the love flame burning.
This single which is receiving a warm reception because of its controversial title is released as Haruna Mubiru's 2nd main stream single this year after Ndimumalilivu, Sijja Kumulekelela and we hope it is going to perform way better than the former single.
On releasing this single Hajji Haruna Mubiru wrote,
Listen, Share and Download this song by clicking the link below...
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|Director :
|Jim Henson , , Randall Balsmeyer , Ken Diego
Explore the world of music and rhythm with your favorite Sesame Street characters featuring the cast of Stomp, the international percussion sensation! When Telly loses his tuba he thinks he will never make music again, but the Stomp cast members teach that everyday items can make music and that music can be made with almost anything! They even use Oscar's trash can! Learn about rhythm and add a little music to your life with the whole Sesame Street gang!
Sesame Street - Let's Make Music is a 2003 English Film stars Jim Henson , , Randall Balsmeyer , Ken Diego , Carlo Alban , Alan Arkin , Paul Benedict , Larry Block , , directed by Ken Diego & music by . 14-01-2003


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Regulatory Compliance Officer
Salary Negotiable
Location SingaporeFULL_TIME
Consultant Sabrina Yap (R1879576)
JobRef 1407540/001
Date posted 11 February 2019 2019-02-112019-04-12 financial-services Singapore SG SGD 4000 4080 4080 MONTH Robert Walters https://www.robertwalters.com.sg
An intriguing job opportunity as a Regulatory Compliance Officer for the APAC region has just been released with one of the global inter-dealer brokerage firms in Singapore. Reporting directly to the Head of Compliance, APAC, this role is looking for an individual with skillful knowledge of the regulatory compliance space.
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Key Responsibilities:
- Assist the Head of Compliance with regard to strategic direction, culture and activity
- Ensure that businesses receive a true 'value added' service from the Compliance function
- Assist with the implementation and management of the Compliance Monitoring Program in APAC
- Provide an active role as a member of the Compliance team, participating in relevant committees, groups and fora as required
- Review and assess any New Business Initiatives
- Carry out face to face training of front office staff and, as required, senior management
- Attend business and control committees as required
To succeed in the Regulatory Compliance Officer role, you will need to be up to date with MAS regulatory requirements and have the ability to implement the requirements into the business. As training of the various lines of business is important to the role, your communication and interpersonal skills will be required.
Key requirements:
- Over two years' experience within Compliance / Regulatory law across diverse fields of knowledge
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I remember as a child, going with my mother into the woods to gather Dandelions for dinner. This was a normal occurrence for us. I never even gave it a second thought, until I grew up and left home and then was faced with the realities of life.
A scalp massage is a simple and effective treatment for hair loss. It stimulates hair growth by increasing blood flow to the scalp. It also helps remove dirt and other debris which can clog the follicles. Spend about 10 minutes each day massaging your fingers throughout your scalp. Be sure to get the top of the head. This is the area of the body which is farthest from the heart and blood flow to this part of the head is often weak.
Encylopedia Britannica says that "iron is the most used and cheapest metal". However iron is soft by nature, very reactive and can corrode. Iron by itself is not effective as a metal, so clearly is not the answer for the rugged pull up bars we are seeking for our home, garage or commercial gyms. While iron and steel are often used interchangeably, they are not one in the same; so much for "pumping iron". Steel is an Lithium 12-hydroxystearate and copper iron alloys are mixtures of iron with other elements. In the case of most common steel, iron is mixed with carbon which gives it its strength and durability.
In the second nitride powder way metals occur out of remedy or are left exposed when the pH Complete Alkalinity and/or Calcium Hardness are left unchecked allowed to go reduced pH beneath seven.two Total Alkalinity below ppm non-Pristine Blue pools Calcium Hardness below ppm The drinking water becomes aggressive the metals are more vulnerable to oxidation. In quite a few scenarios, pool-owners don't properly examination their h2o & more probable depend on the "look" of the water (the water's clear, every thing should be alright). This is typically the situation with blonde hair turning green – very low pH helps bring copper out of option & "plates" it out on the person's hair! Then individuals blame the chlorine! It is really the copper in the drinking water.
Metal art is created by molding and shaping certain kinds of metals such as copper, iron, and sometimes a combination of both. It can be shaped into something that is realistic, while most artists take the abstract route. The result is an elegant piece of art that can be displayed almost anywhere. There are pieces of metal art that needs to be assembled. Some are even made to move while being balanced on a pedestal.
Here's what takes place: metals arrive into your pool each time fresh new, make-up h2o is extra. They're dissolved in the drinking water. Whether or not it's municipal drinking water or well h2o, metals can be current. As the metals accumulate, the greater the opportunity that they will at some point come out of remedy. Once out of remedy, they make the drinking water cloudy or worse, they "plate out" on the pool's surfaces & stain. Metals can occur out of solution as a result of a selection of strategies. But there's 2 that usually take place.
Cardiovascular, or aerobic, workouts have been traditionally defined as exercises that use the major muscles of the body over an extended period of time. This overall effort produced by many muscles working in unison results in greater energy expenditure by the body (that means a significant calorie burn). Cardio is great for burning calories, walking, running, swimming, biking, and rollerblading. And start toning with small weights, like 5 pounds, for arm exercises.
Wrought iron table lamps are formed by bending and wielding so there is an infinite possibility of designs. Whether you're looking for conventional or contemporary, plain or complex; the Wrought Iron's design will absolutely fit. It's modern and yet still looks classical. But, when in doubt, remember that there are interior designers.


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Takeda to Present Positive Data from TOURMALINE-MM3, First Pivotal Phase 3 Placebo Controlled Trial Evaluating Proteasome Inhibitor Treatment in Maintenance Setting
Takeda Pharmaceutical Company Limited (TSE:4502) today announced that data from the Phase 3 randomized, TOURMALINE-MM3 study evaluating the effect of single-agent oral NINLARO™ (ixazomib) as a maintenance therapy in adult patients diagnosed with multiple myeloma who previously responded to high-dose therapy (HDT) and autologous stem cell transplant (ASCT) will be presented at the 60th American Society of Hematology (ASH) annual meeting on Sunday, December 2, 2018 in San Diego, California. NINLARO is currently not approved as a maintenance therapy for multiple myeloma following ASCT.
The trial achieved its primary endpoint with NINLARO resulting in a statistically significant improvement in progression-free survival (PFS) versus placebo in adult patients diagnosed with multiple myeloma who responded to HDT and ASCT as assessed by an Independent Review Committee (IRC) (HR 0.72; p-value=0.002). This corresponds to a 28 percent reduction in risk of progression or death and a 39 percent improvement in PFS with NINLARO compared with placebo. The safety profile of NINLARO in the maintenance setting is consistent with previously reported results of single-agent NINLARO use.
"A growing body of evidence has shown that maintenance therapy in multiple myeloma may prolong the duration of disease control," said Meletios Dimopoulos, MD, Professor and Chairman of the Department of Clinical Therapeutics at the University Athens School of Medicine, Athens, Greece. "As currently approved options are limited and do not include a proteasome inhibitor, there is a need for additional maintenance treatments that can sustain response and have a tolerable safety profile. Data from the TOURMALINE-MM3 clinical trial supports single-agent NINLARO as a potential oral proteasome inhibitor maintenance therapy option post-ASCT."
"The positive results from this pivotal study – the first and only Phase 3 placebo controlled study evaluating a proteasome inhibitor in this setting – support NINLARO as a potential maintenance therapy for patients who have undergone a stem cell transplant," said Jesús Gómez Navarro, M.D., Vice President, Head of Oncology Clinical Research and Development, Takeda. "It is crucial that we continue to support patients by developing treatment options aimed to maintain or deepen response and delay disease progression. According to the findings, patients treated with NINLARO had improved progression-free survival over those in the control arm, which corresponds to a reduced risk of progression or death of nearly one-third."
"As a result of continued research, the multiple myeloma treatment landscape is constantly evolving. While this is encouraging news for the multiple myeloma community, there is still work to be done to further our goal of addressing the unmet needs of patients," said Brian GM Durie, M.D., Chairman of the Board, International Myeloma Foundation. "To that end, the development of additional safe and effective maintenance therapies is essential."
Maintenance Therapy With the Oral Proteasome Inhibitor (PI) Ixazomib Significantly Prolongs Progression-Free Survival (PFS) Following Autologous Stem Cell Transplantation (ASCT) in Patients With Newly Diagnosed Multiple Myeloma (NDMM): Phase 3 TOURMALINE-MM3 Trial Sunday, December 2, 2018, 7:30 – 9:00 a.m., Marriott Marquis San Diego Marina, Grand Ballroom 7
Key findings, which will be presented by Dr. Meletios Dimopoulos, include:
- The trial achieved its primary endpoint with NINLARO resulting in a statistically significant improvement in PFS versus placebo in adult patients diagnosed with multiple myeloma who responded to HDT and ASCT as assessed by an Independent Review Committee (IRC) (HR 0.72; 95% CI: 0.582, 0.890; p-value=0.002). This corresponds to a 28 percent reduction in risk of progression or death and a 39 percent improvement in PFS with NINLARO.
- Per IRC assessment, median PFS for patients in the NINLARO arm was 26.5 months compared to 21.3 months in the placebo arm.
- Conversion from documented minimal residual disease (MRD) positivity at study entry to MRD negativity occurred at a higher rate among patients treated with NINLARO compared with placebo (12 percent versus 7 percent, respectively).
- NINLARO maintenance led to higher rates of deepened response compared with placebo (relative risk 1.41; 95 percent CI: 1.10, 1.80; p=0.0042).
- PFS benefit was seen broadly across subgroups, including ISS III (HR 0.661), PI-exposed (HR 0.750), PI-naïve (HR 0.497), and patients with high-risk cytogenetics (HR 0.625).
- Secondary endpoints including median PFS2 and OS have not yet been reached in either arm. Median follow-up was 31 months.
- Global Quality of Life scores (EORTC QLQ-C30) for patients on NINLARO were similar to those on placebo.
The safety profile of NINLARO in the maintenance setting is consistent
with previously reported results of single-agent NINLARO use.
- Discontinuation of treatment due to adverse events (AE) was low, at 7 percent in the NINLARO arm compared to 5 percent in the placebo arm.
- Grade ≥3 AEs were experienced by 42 percent of patients receiving NINLARO versus 26 percent receiving placebo.
- Patients in the NINLARO arm experienced serious AEs at a rate of 27 percent versus 20 percent in the placebo arm.
- Common grade ≥3 AEs in both the NINLARO and placebo arms included infections (15 and 8 percent, respectively) including pneumonia (6 and 4 percent, respectively), gastrointestinal disorders (6 and 1 percent, respectively), neutropenia (5 and 3 percent, respectively) and thrombocytopenia (5 and <1 percent, respectively).
- On the NINLARO arm, peripheral neuropathy events were observed in 19 percent of patients versus 15 percent on the placebo arm. In the NINLARO arm, <1 percent of peripheral neuropathy events were Grade 3 compared with 0 in the placebo arm.
- The rate of second primary malignancies was 3 percent in both arms.
- One patient in the NINLARO arm died on study while no patients in the placebo arm did. The single study death was considered to be treatment-related and was due to pneumonia.
About the TOURMALINE-MM3 Trial
TOURMALINE-MM3 is a randomized, placebo-controlled, double-blind Phase 3 study of 656 patients, designed to determine the effect of NINLARO® (ixazomib) maintenance therapy on progression-free survival (PFS), compared to placebo, in participants with multiple myeloma who have had a response (complete response [CR], very good partial response [VGPR], or partial response [PR]) to induction therapy followed by high-dose therapy (HDT) and autologous stem cell transplant (ASCT). The primary endpoint is progression-free survival (PFS). A key secondary endpoint includes overall survival (OS). For additional information: https://www.clinicaltrials.gov/ct2/show/NCT02181413.
About NINLARO ™ (ixazomib) capsules
NINLARO™ (ixazomib) is an oral proteasome inhibitor which is also being studied across the continuum of multiple myeloma treatment settings as well as systemic light-chain (AL) amyloidosis. It was the first oral proteasome inhibitor to enter Phase 3 clinical trials and to receive approval. NINLARO was approved by the U.S. Food and Drug Administration (FDA) in November 2015 following a priority review and by the European Commission in November 2016. In the U.S. and Europe, NINLARO is indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received at least one prior therapy. NINLARO has received marketing authorization by regulatory authorities in more than 60 countries.
Ixazomib was granted orphan drug designation in multiple myeloma in both the U.S. and Europe in 2011 and for AL amyloidosis in both the U.S. and Europe in 2012. Ixazomib received Breakthrough Therapy status by the U.S. FDA for relapsed or refractory systemic light-chain (AL) amyloidosis, a related ultra orphan disease, in 2014. The Japanese Ministry of Health, Labour and Welfare granted Orphan Drug designation to ixazomib in 2016.
The comprehensive ixazomib clinical development program, TOURMALINE, includes a total of six ongoing pivotal trials – five, which together are investigating every major multiple myeloma patient population, and one in light-chain amyloidosis:
- TOURMALINE-MM1, investigating ixazomib versus placebo in combination with lenalidomide and dexamethasone in relapsed and/or refractory multiple myeloma
- TOURMALINE-MM2, investigating ixazomib versus placebo in combination with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma
- TOURMALINE-MM3, investigating ixazomib versus placebo as maintenance therapy in patients with newly diagnosed multiple myeloma following induction therapy and autologous stem cell transplant (ASCT)
- TOURMALINE-MM4, investigating ixazomib versus placebo as maintenance therapy in patients with newly diagnosed multiple myeloma who have not undergone ASCT
- TOURMALINE-AL1, investigating ixazomib plus dexamethasone versus physician choice of selected regimens in patients with relapsed or refractory AL amyloidosis; this study is currently enrolling
- TOURMALINE-MM5, investigating ixazomib plus dexamethasone versus pomalidomide plus dexamethasone in patients with relapsed and/or refractory multiple myeloma who have become resistant to lenalidomide; this study is currently enrolling
For more information about actively enrolling Phase 3 studies please visit: https://www.tourmalinetrials.com/
In addition to the TOURMALINE program, ixazomib is being evaluated in multiple therapeutic combinations for various patient populations in investigator initiated studies globally.
NINLARO ™ (ixazomib) capsules: Global Important Safety Information
Thrombocytopenia has been reported with NINLARO (28% vs. 14% in the NINLARO and placebo regimens, respectively) with platelet nadirs typically occurring between Days 14-21 of each 28-day cycle and recovery to baseline by the start of the next cycle. It did not result in an increase in hemorrhagic events or platelet transfusions. Monitor platelet counts at least monthly during treatment with NINLARO and consider more frequent monitoring during the first three cycles. Manage with dose modifications and platelet transfusions as per standard medical guidelines.
Gastrointestinal toxicities have been reported in the NINLARO and placebo regimens respectively, such as diarrhea (42% vs. 36%), constipation (34% vs. 25%), nausea (26% vs. 21%), and vomiting (22% vs. 11%), occasionally requiring use of antiemetic and anti-diarrheal medications, and supportive care.
Peripheral neuropathy was reported with NINLARO (28% vs. 21% in the NINLARO and placebo regimens, respectively). The most commonly reported reaction was peripheral sensory neuropathy (19% and 14% in the NINLARO and placebo regimens, respectively). Peripheral motor neuropathy was not commonly reported in either regimen (< 1%). Monitor patients for symptoms of peripheral neuropathy and adjust dosing as needed.
Peripheral edema was reported with NINLARO (25% vs. 18% in the NINLARO and placebo regimens, respectively). Evaluate patients for underlying causes and provide supportive care, as necessary. Adjust the dose of dexamethasone per its prescribing information or the dose of NINLARO for severe symptoms.
Cutaneous reactions occurred in 19% of patients in the NINLARO regimen compared to 11% of patients in the placebo regimen. The most common type of rash reported in both regimens was maculo-papular and macular rash. Manage rash with supportive care, dose modification or discontinuation.
Hepatotoxicity, drug-induced liver injury, hepatocellular injury, hepatic steatosis, and hepatitis cholestatic have been uncommonly reported with NINLARO. Monitor hepatic enzymes regularly and adjust dose for Grade 3 or 4 symptoms.
Pregnancy- NINLARO can cause fetal harm. Advise male and females patients of reproductive potential to use contraceptive measures during treatment and for an additional 90 days after the final dose of NINLARO. Women of childbearing potential should avoid becoming pregnant while taking NINLARO due to potential hazard to the fetus. Women using hormonal contraceptives should use an additional barrier method of contraception.
Lactation- It is not known whether NINLARO or its metabolites are excreted in human milk. There could be potential adverse events in nursing infants and therefore breastfeeding should be discontinued.
Hepatic Impairment: Reduce the NINLARO starting dose to 3 mg in patients with moderate or severe hepatic impairment.
Renal Impairment: Reduce the NINLARO starting dose to 3 mg in patients with severe renal impairment or end-stage renal disease (ESRD) requiring dialysis. NINLARO is not dialyzable and, therefore, can be administered without regard to the timing of dialysis.
Co-administration of strong CYP3A inducers with NINLARO is not recommended.
The most frequently reported adverse reactions (≥ 20%) in the NINLARO regimen, and greater than in the placebo regimen, were diarrhea (42% vs. 36%), constipation (34% vs. 25%), thrombocytopenia (28% vs. 14%), peripheral neuropathy (28% vs. 21%), nausea (26% vs. 21%), peripheral edema (25% vs. 18%), vomiting (22% vs. 11%), and back pain (21% vs. 16%). Serious adverse reactions reported in ≥ 2% of patients included thrombocytopenia (2%) and diarrhea (2%). For each adverse reaction, one or more of the three drugs was discontinued in ≤ 1% of patients in the NINLARO regimen.
For European Union Summary of Product Characteristics: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/003844/WC500217620.pdf
For US Prescribing Information: https://www.ninlarohcp.com/pdf/prescribing-information.pdf
For Canada Product Monograph: http://www.takedacanada.com/ninlaropm
About Takeda Pharmaceutical Company
Takeda Pharmaceutical Company Limited (TSE: 4502) is a global, research and development-driven pharmaceutical company committed to bringing better health and a brighter future to patients by translating science into life-changing medicines. Takeda focuses its R&D efforts on oncology, gastroenterology and neuroscience therapeutic areas plus vaccines. Takeda conducts R&D both internally and with partners to stay at the leading edge of innovation. Innovative products, especially in oncology and gastroenterology, as well as Takeda's presence in emerging markets, are currently fueling the growth of Takeda. Approximately 30,000 Takeda employees are committed to improving quality of life for patients, working with Takeda's partners in health care in more than 70 countries.
For more information, visit https://www.takeda.com/newsroom/.
Additional information about Takeda is available through its corporate website, www.takeda.com, and additional information about Takeda Oncology, the brand for the global oncology business unit of Takeda Pharmaceutical Company Limited, is available through its website, www.takedaoncology.com.
View source version on businesswire.com: https://www.businesswire.com/news/home/20181202005031/en/
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text:
The story is about three close friends growing apart and becoming each enemies, while unaware that they used to be very close friends when they used to be orphans. Will they found out their true identities?
Type: Scripted
Languages: Turkish
Status: Ended
Runtime: 60 minutes
Premier: 2006-04-14
Kaybolan Yillar - RTV21 - Netflix
RTV21 (an acronym for Radio Televizioni 21; English: Radio and Television 21) is a media company based in Pristina, Kosovo, which includes a radio (est. 1998), a television (est. 1999), and a website (est. 2001).


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Senior Administrative Assistant
POSITION: Senior Administrative Assistant
DEPARTMENT: School of Music
REPORTS TO: Director, School of Music
Under the supervision of the Director of the School of Music, this position will facilitate the daily operation of the School of Music. Administrative tasks include scheduling of courses and rooms, overseeing student advising and registration, preparation of faculty contracts, and budget management. The Senior Administrative Assistant works with numerous administrative and academic offices across campus including the Dean of the College of Performing Arts, Registrar, Finance, Admissions, Student Services, and Advancement. This position supervises work study students.
- Advising & Registration
- Manages and coordinates all administrative aspects of Academic Advising and Registration for the School of Music.
- Handles pre-advising and registration of new students; assists with transfer students. Coordinates class placements with various Division Heads and Area Coordinators. Additional advising during Orientation.
- Oversees current student registration materials, corrects errors as necessary.
- Manages the submission of the Course Section Offerings bulletin: creates new semester, manages room assignments, and updates any changes throughout the semester. Ensures that the necessary equipment is available in each room used by the School of Music.
- Consults with Director on program curricula and course listings; manages curricular tables for each degree program; submits changes as necessary.
- Oversees pre-advising and other curricular tasks related to the School of Music programs, such as transfer credits, electives, and course schedules.
- Oversees the timely submission of materials and forms to the Registrar's Office, including Drop/Add forms, grade rosters, and Change of Grade forms.
- Corresponds with students and faculty during Registration and Drop/Add periods to assist with scheduling and registration issues.
- Works with School's Chief Advisor to train new advisors.
- Manages all aspects of School of Music Advising Blockout, including distribution of materials and information to students and advisors, coordinates and leads pre-Advising meetings, and other related activities.
- Oversees the completion of forms and graduation approval for the Graduate programs in the School of Music. Assists the Head of Music Education in advising, registration and scheduling of courses in the (summer) MM in Music Education program.
- Works closely with the Dean's office of the College of Performing Arts to prepare the School and College for New Student Orientation.
- Creates jury schedules in conjunction with Department Chairs; confirms student registration for juries. Using Remark software, scans and processes jury results to be used for assessment.
- Recruitment
- Assists Chief Advisors with Transfer Credit Evaluations.
- Coordinates, in consultation with Director, activities and materials for School of Music presence at Open House.
- Assists in coordinating off-campus recruitment efforts, as needed.
- Assists with Audition Day as needed; includes managing Audition Day in the absence of the Administrative Assistant.
- Faculty (Payroll, Contracts, Management)
- In consultation with Director, oversees all Part-Time and Full-Time faculty course assignments for Course Section Offering bulletin and contracts. Inputs all course information using the Colleague database.
- Collects monthly payroll log sheets from faculty. Calculates information to be submitted to the Payroll department each month; oversee budget compliance.
- Maintains a database of applied lessons records and ensemble rehearsals; distributes information to Department Chairs and Ensemble coordinator.
- Handles orientation of new School of Music faculty to University and School policies and procedures.
- Trains faculty on the use of various online tools (Portal, Google Apps, etc.) through the distribution of documents and video tutorials.
- Budget
- Assists Director in preparation of the School budget; consults on various aspects of annual request. Enters all budget request information into Colleague database.
- Monitors the operating budget for the School of Music, as well as any area-specific and restricted budgets.
- Data for Institutional Research & Development
- Compiles information needed for the Office of Institutional Research.
- Management of School
- Collects, maintains and updates all School records including those pertaining to students, faculty, contracts, course syllabi, etc.
- Oversees the Work Study budget for the School of Music: confirms that job descriptions are accurate, processes Student Employment Authorization forms to ensure students are hired and paid at a correct rate, keeps records of hours worked and monitors the allotted budget for each sub-area. May directly or indirectly supervise student employees.
- Establishes and manages a master schedule for the School of Music, to include student and faculty recitals, master classes, meetings, concerts and jury examinations. Coordinates scheduling and calendar management with production staff and/or other departments.
- In conjunction with Director, oversees Senior Showcases: ensures that proper policies and procedures are being followed, and that department requirements are reflective of School requirements.
- Arranges for the tuning, maintenance and moving of pianos. Coordinates classroom, rehearsal, and concert schedules with tuners and movers.
- Assists the Coordinator of School of Music Pre-College Activities in the scheduling of classes and events for the Creative Jazz Institute.
- Creates programs for various School of Music performances and other special events.
- Serves as Director's delegate in his/her absence.
Required Knowledge, Skills, and Abilities:
- Experience with:
- Macintosh platform
- Microsoft Office Suite
- Google Apps
- Internet and email; social networking sites
- Telephone, fax machine, photocopier
- Familiar with (will train if necessary):
- Ellucian Colleague software
- Adobe Creative Suite
- Digication Course Management software
- Gravic Remark Office OMR software
- Strong communication skills.
- Ability to establish effective working relationships with a wide range of people and maintain confidentiality required.
The above statements are intended to describe the general nature and level of work performed by the incumbent; they do not purport to describe all functions. Incumbent may be assigned other duties, and the essential functions may change from time to time as necessary.
• Bachelor's degree in Music or equivalent experience; Master's degree preferred.
• Experience working in higher education.
• Administrative/management experience.
• Bookkeeping knowledge helpful.
The University of the Arts—a leader in developing visual and performing artists and designers since 1876—is the only university in the United States that allows its students to collaborate across traditional lines. With more than 30 majors, 30 minors and 13 graduate programs in visual arts, performing arts, design and liberal studies, UArts develops alumni who are not only leaders in their disciplines, but also creative thinkers able to succeed in any path they choose. Our nearly 1,900 students study and create on our campus in the heart of Philadelphia's Avenue of the Arts, the city's cultural center, within walking distance of hundreds of galleries, museums, theaters and other performing arts venues.
TO APPLY: Interested, qualified applicants should submit letters of application, CV, to the Human Resources Department via email to firstname.lastname@example.com. Please ensure job title is in the Subject line.
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