text:
Kevin B. O'Reilly
March 2016—For laboratories performing virology testing, taking advantage of molecular testing's superiority to traditional testing methods is a no-brainer. But leaders in the University of Michigan's clinical microbiology laboratory have found that the push to go all molecular for virology testing must be tempered by attentiveness to clinician preferences and a collaborative approach that's likelier to make the journey a success.
So says Duane Newton, PhD, clinical microbiology director at the University of Michigan Health System in Ann Arbor. Compared with a high of nearly 6,000 viral cultures performed in-house during the 2009–2010 fiscal year, the Michigan clinical microbiology laboratory performed fewer than 1,000 viral cultures during 2014–2015, and that figure appears to be dropping to "essentially zero" in this fiscal year.
It is unclear how many laboratories performing virology testing have gone this far in their transition to molecular, Dr. Newton tells CAP TODAY.
"We're at least in the middle part of a journey where it's becoming more commonplace," he says. "What is clear is there's some contention and debate about approaches, and differences of opinion about how to approach this [move to molecular].… There's lots of communication that has to happen within your institution. What might be right for mine might not be right for your institution."
At Michigan, one of the few examples in which molecular is not the go-to method is for nonblood specimens tested for cytomegalovirus. In retrospect, Dr. Newton said during a session at the Association for Molecular Pathology's annual meeting last November, this was a case where he and his laboratory colleagues moved too far too fast.
"One of the mistakes that we made was assuming too much," said Dr. Newton, who is also associate director of the Division of Clinical Pathology and an associate professor of pathology at Michigan. "In our quest to eliminate cultures, CMV culturing was one of our targets. We started evaluating quality assays for testing of nonblood specimens, primarily respiratory tract specimens. We went through the process of validating specimen types and demonstrating that we could consistently and accurately detect CMV with those specimens and as a result felt comfortable discontinuing CMV cultures.
"That's when we decided to talk to clinicians and say, 'This is what we're going to do,'" Dr. Newton added. "And our infectious disease doctors and lung transplant pulmonologists said, 'Wait a minute. PCR is going to be way too sensitive. We already over respond to the positive cultures. And now you're going to give us 30 to 50 percent positives, and people are going to over respond to this as well.'"
In response, Dr. Newton and his laboratory colleagues decided to cancel plans to perform CMV testing by PCR and developed a process to send out any requests for culture so they could eliminate the culturing in-house. Nonetheless, it was a lesson learned.
"It's one of those things where we should have talked about this before we went down this road," he said. "It reinforces to us that need to engage the users as early in the process as possible."
Another example, more recently, where Dr. Newton has opted to defer to clinicians is in neonatal herpes simplex virus testing. Some pediatricians and infectious disease physicians at his institution objected to using PCR for HSV in neonatal patients, noting that the American Academy of Pediatrics' Red Book embraces culturing as the gold standard method in these cases.
These clinicians "were not supportive of using molecular in this scenario because they felt it was too sensitive and would pick up colonization that you can have exposure to during birth. They felt that it was not necessarily infection—that it's superficial contamination and that culturing would be definitive because it's more specific for infection," Dr. Newton tells CAP TODAY.
How is neonatal HSV testing handled now?
"We send it out for culture," Dr. Newton says, noting there is about one request a month for HSV culturing. "The volume is too low to have it in-house but it's available on request, when that clinical situation arises, and that's something communicated by the clinical teams [to] the lab so that we can facilitate that. And that was one of the parts of the decision. Since we weren't going to perform conventional methods anymore, including culturing, we needed to figure out how our level of service needed to change to accommodate that."
Pathology residents help manage all viral culture test requests by consulting a protocol for when send-out of such test requests is warranted, Dr. Newton said at the AMP meeting.
The pathology residents will "look at the order, look at the patient's chart, and communicate with the physician as necessary," he said. "We want to see that this is a clinical situation that actually requires it, or is the clinician just checking boxes and doesn't realize we have better tests in-house. Most requests are actually eliminated through that process. The ones where there really is a justification, the clinicians are aware of that and now are giving us a heads-up, saying we have this patient and need to have a culture for X, Y, and Z. So it's a pretty streamlined process."
Acquiescing to clinician concerns about molecular tests being too sensitive is a practice that not everyone endorses.
During the question-and-answer portion of Dr. Newton's AMP talk, Paul Schreckenberger, PhD, rose from the audience to speak.
"As a lab director, I have a real problem with saying, 'Let's use less sensitive tests.' I think that physicians should know what's out there and they should use that information, along with their clinical judgment and with their knowledge of what's going on with the patient," said Dr. Schreckenberger, clinical microbiology director at Loyola University Medical Center, Maywood, Ill. "To me, it's a slippery slope to say that a molecular test is not good because it results in false-positive test results. It is not a false-positive if the target is present in the sample—for example, herpes virus. It's just a matter of whether it's connected to infection."
In an interview, Dr. Newton says he would frame the issue differently.
"The question is in what clinical scenarios is it most appropriate to utilize molecular," he says. "It is analytically more sensitive, but I think the issue is specificity from a clinical perspective. And there are a lot of examples where maybe it is analytically too sensitive and you lose some clinical specificity."
Objections to molecular methods for detecting viral pathogens are not always about sensitivity, Dr. Newton adds. The Michigan clinical microbiology laboratory had discontinued direct fluorescent antibody testing for respiratory virus infections when it implemented molecular, but it maintained DFA for detection of herpes simplex and varicella zoster viruses from lesions.
"As the assays became available and validated in our labs for PCR for herpes and varicella, our desire was to discontinue DFA," he says. With a desire to avoid the implement-first, ask-later approach, Dr. Newton shared the plan with heavy clinician users of this testing.
"The pushback really revolved around turnaround time," he says. Accustomed to two-hour TATs with DFA testing, "once-a-day molecular testing wasn't something they were super excited about."
In response, Dr. Newton and his colleagues have changed their approach, switching to Focus Diagnostics' 3M Integrated Cycler, a platform "that is much more amenable to more frequent, small batches during the day. We're in the process of going live with herpes and varicella on that platform…so we can do multiple runs during the day."
The 3M Integrated Cycler's analytical run time for Focus' HSV and VZV assays is about one hour, Dr. Newton says. The agreement with clinicians is to perform two runs, one in the morning and one in the afternoon, seven days a week.
At the Cleveland Clinic, HSV for lesions is one of the few areas in which the virology laboratory still uses a nonmolecular method, Quidel's ELVIS HSV Test System. Gary W. Procop, MD, MS, who directs molecular microbiology, virology, mycology, and parasitology at Cleveland Clinic, says they still do traditional culturing for enterovirus other than cerebrospinal fluid and for CMV other than blood.
"That's about it," Dr. Procop says. "Every once in a while, we'll do a test-of-cure culture, particularly in an immunocompromised patient whose symptoms have not resolved."
"The real paradigm shift," he adds, "is not only the multitude of molecular virology tests available, but that many of them are available for platforms that are very simple to use, platforms that can be used for a variety of different pathogens, and that can be implemented in 200-bed hospitals. In the past, tests that could not be done locally were referred out. Now, many of these tests can be performed locally in smaller-sized hospitals with high-quality results."
Unlike Michigan, Cleveland Clinic does not send out all test orders requesting culture.
"We've retained some ability. Many places would just make it a send-out," says Dr. Procop, professor of pathology at the Cleveland Clinic Lerner College of Medicine. "Some of these, like the influenza culture, have been retained as a lab-order only. It's only going to be placed if the doctor calls us, explains the clinical need and rationale, and then it may get approved. If we put all the testing possibilities on the test menu order, some busy person is going to check all the boxes. There's a lot of utilization management that goes into these efforts."
While lacking hard data on how far laboratories performing virology testing across the country have gone in giving up traditional testing methods, Dr. Procop says commercial development is making the biggest difference in speeding the transition.
"The more turnkey that vendors make their product, the wider the distribution it will have," he says. "For many of these tests that we have been doing for years—not just here but at other academic medical centers—you had to have people to design the primers and the probes and construct the assays. But poor old St. Elsewhere hospital didn't have that. They also couldn't sustain the cost infrastructure.
"What's really been a change in the development and marketing from numerous manufacturers is that many of these companies followed Cepheid's lead of having single-use cartridges. You do this, and you throw it away. It all comes prepared. You don't need basic scientists there, and it's FDA approved."
"The traditional virology laboratory," Dr. Procop concludes, "has been transformed to a molecular virology laboratory."
Navigating this sea change, Michigan's Dr. Newton insists, requires a cooperative style from the laboratory.
"There's very little in the way of things that we can't do [technologically]," he says. "If you have the resources, you can do a lot, but you have to have a willingness to keep patient care at the front of your decision-making process. It's about what's best for the patients, not what's convenient or easy for the laboratory."
"Here I feel fortunate," Dr. Newton adds, "that I don't have to battle too much with administrators, and I don't have to battle too much with our clinical colleagues. I have a great relationship with my colleagues. I don't always get what I want. And they don't always get what they want."
Kevin B. O'Reilly is CAP TODAY senior editor.


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Multiple Teams · Franklin County High School Girls Varsity Volleyball falls to Centerville High School 0-3
Tuesday, September 8, 2015 6:00 PM Franklin County High School AWAY 0 Centerville High School HOME 3 Game Recap Kamryn Mccool led the cats with 4 kills along with 3 stuff blocks and 1 ace on the night. Hayley Lattarulo led the team with 6 assists. Karlie Schell led the team with 7 digs. Box

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Today, 02:27 PM
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Day 1 :
Arrival at cochin airportrailway station. Then to Munnar. This beautiful hill station was once the summer capital of the British Government in India. The never ending vast expanse of tea plantations and the round the year moderate climate makes it a lit Transport Included.
Day 2 :
Visit to Rajamala-house of the highly endangered mountain goats-the Niliri Thars.Then to Lakkam water falls which is
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Morning to Top Station offers panoramic view of the neighboring state of Tamil Nadu.then to Echo point and Mattupetty Dam. Speed boating facilities are available here.The dam is flanked by forests and vast expanse of grass land on one side and the Kun Transport Included
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Drive to Kumarakam. By noon check in at the backwater resort in Kumarakam. After noon at leisure. Overnight stay t Kumarakom.
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Day 6 :
Morning after breakfast proceed to Alleppey. By noon check in at the house boat in Alleppey for a 20 hour house boating through the lenders backwater of Kerala .On the way you will witness a full range of life and activities and some mind bogging Sc.
Transport Included
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Day 8 :
Morning after breakfast proceed for a city tour of Trivandrum covering Napier Museum and Sri Padmanabha Swamy Temple. Afternoon at leisure in Kovalam. Overnight at Kovalam.
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Day 9 :
Morning after breakfast proceeds to Trivandrum airportrailway station for onward journey. Trivandrum
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Tulip Orange Homes are inspired from orange tulips which are a spring beauty. The homes boast of having a firm foundation and strong structure just like the deeply rooted tulips in dense soil. Splashes of orange in tulips propagate charm, passion, freshness, warmth and radiance. We at Tulip Group aim to capture this very essence of life and weave it into superior real estate solutions.
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Killeen Latin Personals click on a member below to meet them
Latin women are some of the sexiest women on the face of the planet. Everything about them is hot. If you have ever dated a Latin woman or had a close relationship with one you know how sexy they are. If all you've ever done is admire them from long distance and you want to change that for good, read on.
Latin women are just women. Extremely sexy versions of women, but women just the same. That one small piece of information is crucial to your future success because women have two rules that they are hard wired to follow. Learn and fully understand these rules in order to go from clumsy and frustrated around women to carefree, relaxed and most importantly, successful.
Non-Negotiable # 1: Men dress for comfort. Women dress for men.
I don't care where in the world you are, women wear whatever men want to look at. Guys wear what feels good. Women wear what looks good, to men. I didn't make this rule up. I just notice it and learned to put it to use.
Women, especially Latin women, are hard wired to dress to show off their bodies. They will put themselves through all kinds of hell just to look the way they do when they walk out the door.
They will wear painfully high heel, wonderfully tight jeans and all version of thongs just to be more attractive to men. Whatever assets they have, they will dress to show it off. Tight low-rider jeans or halter top with no bra. Their motto is, If it looks good, wear it.
Your job is to enjoy the show they are putting on. Women's clothing is somewhat like your freshman music appreciation class. They play the music, your job is to appreciate it.
Non-Negotiable # 2: Women cannot resist confidence.
Confidence is to Latin women as catnip is to cats. It turns them on tremendously and there's nothing they can do about it. Believe it or not, The easiest way to show confidence is just to ignore them. I don't mean entirely, what would be the point in that? I mean after you have let them know in no uncertain terms that you know that they are sexy, just ignore them so they know that there's always another train coming.
A strong attitude is the most attractive thing to Latin women. Regardless of how hot the Latin woman in front of you is always act as if you just left someone ten minutes ago who was twice as hot. Once you accomplish this, they will begin chasing you. I don't know why this works. It just does. Try it and see.
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Karen Saffles-Slater, director of Coordinated School Health for Bradley County Schools has this year been honored with two awards for her work. She was one of five regional recipients of … more
By CHRISTY ARMSTRONG | 12/14/18
Polk County residents have been fortunate for more than three decades with "one of their own" in the Polk County Clerk's Office. The trend will continue into the foreseeable future.Polk County native … more
By LARRY C. BOWERS | 1/7/19
A Cleveland woman who was seriously burned in a house fire Wednesday died Thursday morning in an Atlanta-area hospital.The woman, Mamie Perkins, 75, suffered burns when the fire took place at her … more
By TIM SINIARD | 2/15/19
Upcoming events, plans and achievements were discussed Tuesday for the The Cleveland Bradley County Public Library Board monthly meeting. The Ocoee River Regional Library report, which … more
By COLBY DENTON | 11/28/18
The Bradley County Board of Education on Thursday approved the purchases of equipment at two schools, in light of new state law which will require drinking water to be tested for … more
By CHRISTY ARMSTRONG | 12/14/18
Cleveland Utilities President and CEO Tim Henderson says Mountain Dew is a popular soft drink among the people of Nepal, as well as its teeming population of monkeys.While in Nepal during a recent … more
By TIM SINIARD | 1/7/19
Proudly displaying their BEST Partnership certificates the Chamber's newest BEST partners is a relationship between Tennessee Christian Preparatory School and McIntire & Associates Insurance Inc. From left, front, are Tennessee Christian Preparatory School students, McKinley Massengill, Caden Smith, Cormac Bear, Nathaniel Rymer, Isaiah Ellis and Sherry Crye, Chamber Workforce Development director; back, representativews from Tennessee Christian Preparatory School Lacy Laman, Lower School principal; Candace Goff, assistant director of Community Relations; Wendy Benton, Development & Community Relations director; Brad Benton, board of trustees president; Dr. Jimmy Harper, president; and from McIntire & Associates Insurance, Bob McIntire, president; and Todd Walker, partner. McIntire & Associates, TCPS Form New BEST partnership more
The Cleveland Bradley Business Incubator's executive director has issued a statement addressing the recent death of a business tenant who was facing five counts of animal cruelty.Cleveland Police … more
By TIM SINIARD | 2/15/19
A Cleveland man serving a life sentence for two murders has died in prison.more
By AUTUMN HUGHES | 12/14/18
The Bradley County Trustee's Office will provide four satellite sites Saturday for the payment of property taxes in advance of the Feb. 28 deadline.Satellites will be offered at Oak Grove, Hopewell … more
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Enrichment Quotes (displaying: 1 - 22 of 22 quotes )
How aware are we of our own inner life, our spirituality-something so intangible yet so priceless? How much effort do we make to perceive that which is not obvious, which can neither be seen nor heard? I believe the exploration and enrichment of the human spirit is what determines our very humanity. Such enrichment provides an inner compass that can lead civilizations to greatness.
Why do people often feel bad in good environments and good in bad environments? Why did Mother Teresa think that affluent Westerners often seemed poorer than the Calcutta poor, the poorest of the poor? The paradox comes to pass because the impoverishments and enrichments of a self in a world are not necessarily the same as the impoverishments and enrichments of an organism in an environment.
There is only one real misfortune: to forfeit one's own good opinion of oneself. To have lost one's self-respect: that is what unhappiness is. Oh, I have always known that so well! Everything else is part of the game, an enrichment of one's life; in every other form of suffering one can feel such extraordinary self-satisfaction, one can cut such a fine figure. Only when one has fallen out with oneself and no longer suffers with a good conscience, only in the throes of stricken vanity - only then does one become a pitiful and repulsive spectacle.
What binds me to others must grow out of what binds me to the most exuberant and demanding part of my will to live; not the other way round. It is always myself that I am looking for in other people; my enrichment, my realization. Let everyone understand this and 'each for himself' taken to its ultimate conclusion will be transformed into 'all for each'. The freedom of one will be the freedom of all.
Because of its increasing triviality, everyday life has gradually become our central preoccupation. No illusion, sacred or deconsecrated, collective or individual, can hide the poverty of our daily actions any longer. The enrichment of life calls inexorably for the analysis of the new forms taken by poverty, and the perfection of the old weapons of refusal.
While God is not the author of evil and He never prompts or condones sin, nothing occurs without His sovereign oversight. Others may choose to do evil deeds and God's people may suffer in the short term, but He will transform the evil intentions of evil people into opportunities for the enrichment of those in His care.
At some point, one asks, "Toward what end is my life lived?" A great freedom comes from being able to answer that question. A sleeper can be decoyed out of bed by the sheer beauty of dawn on the open seas. Part of my job, as I see it, is to allow that to happen. Sleepers like me need at some point to rise and take their turn on morning watch for the sake of the planet, but also for their own sake, for the enrichment of their lives. From the deserts of Namibia to the razor-backed Himalayas, there are wonderful creatures that have roamed the Earth much longer than we, creatures that not only are worthy of our respect but could teach us about ourselves.
Those sentimental radio hits, with their artificial naivete and empty crudities, are the pitiful remains and the maximum that people will tolerate by way of mental effort; it's a ghastly desolation and impoverishmment. By contrast, we can be very glad when something affects us deeply, and regard the accompanying pains as an enrichment.
[The fairy tale] stirs and troubles him (to his life-long enrichment) with the dim sense of something beyond his reach and, far from dulling or emptying the actual world, gives it a new dimension of depth. He does not despise real woods because he has read of enchanted woods: The reading makes all real woods a little enchanted." —C. S. Lewis, in Of Other Worlds
There is nothing so American as our national parks. The scenery and the wildlife are native. The fundamental idea behind the parks is native. It is, in brief, that the country belongs to the people, that it is in process of making for the enrichment of the lives of all of us. The parks stand as the outward symbal of the great human principle.
Iran's continued drive to develop nuclear capabilities, including troubling enrichment activities and past work on weaponization documented by the IAEA, and its continued support to groups like Hezbollah, Hamas and other terrorist organizations make clear that the regime in Tehran is a very grave threat to all of us.


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Sex Education is a British comedy-drama created by Laurie Nunn and stars Asa Butterfield (Miss Peregrine's Home for Peculiar Children), Gillian Anderson (X-Files), Emma Mackey (Summit Fever), Ncuti Gatwa (Stonemouth), Connor Swindells (Jamestown) and Kedar Williams-Stirling (Two Graves).
With 'Young Justice: Outsiders' being split into two parts, fans are once again left waiting for more adventures. Luckily, there are plenty of other action-packed and emotionally-charged shows to watch in the meantime.
The new teen drama series from Netflix follows the story of a high school student who starts a business by giving advice on sex and relationships to the students.
The characters on AMC's The Walking Dead may be struggling with the zombie apocalypse, but Rick, Daryl, Carol, and the other characters each represent one of Carl Jung's classic human archetypes.
Breaking news stories affect us when we hear and see that something bad has happened. We have been impacted psychologically by the reporting of these events that seem to increase daily in our society.
Are you looking for TV shows like Pretty Little Liars? You've come to the right place. Let's take a look at some similar TV shows.
It's been 13 years since the first season of Degrassi aired. What are Drake, Miriam McDonald, Jake Epstein, and all the other original cast members doing now?
CW's Supernatural has gained acclaimed success. It's not simply two boys chasing ghosts, most of these episodes will have you in hysterics.
If you are looking for the funniest rom-com franchises Thailand has to offer, check out these 10 TV shows.
Through the nearly two decades of Hell's Kitchen there have been lots of crazy moments. Here are five of them.
This article lists all the songs heard in Season 1 of the NBC television series "Life" starring Damian Lewis and Sarah Shahi, which lasted for 2 seasons from 2007 to 2009.
Smallville was filled with characters from the DC Universe. Here is a list of superheroes whom made an appearance during Smallville's 10 year run and joined Clark Kent on his journey to becoming Superman.
Black Sails has been consistent in its delivery of quality content over the course of 3 seasons. Are you looking for similar TV shows? You've come to the right spot!
Kang Gary has won some of the most important episode of Running Man. He has also created some of the most memorable variety show characters but he was not always like this. Let's look back.
With television being so ubiquitous in today's culture, it's hard to imagine a time when few households had TVs, most shows were in black and white, and tropes we now consider cliche were brand new.
Are you looking fro some good TV shows like/similar to American Horror Story while you wait for the next season to air? You have landed on a perfect place.
Are you looking for TV shows like 'Vikings'? You've come to the right place. Let's take a look at some other similar series.
A popular fan theory is roaming around involving the Woman Twice Dead and one of the Doctor's closest companions. I detail the specifics behind this theory and give my opinion on it.
"Celebrity Big Brother 2" has come to an end. Here are some interesting numbers about the reality show.
The Andy Griffith Show set in Mayberry with Sheriff Andy, Deputy Barney Fife, Opie and Aunt Bee. Best episodes with Andy Griffith, Don Knotts and Ron Howard. Character sketches and actor biographies.
From mind-melding Vulcan's with unparalleled logic, to desert island castaways capable of building anything under the sun using only bamboo sticks and coconuts, all the greatest TV smarties are here.
What is Zach Braff, Sarah Chalke, Donald Faison, Judy Reyes and the rest of the Scrubs cast up to now? Find out where the Scrubs cast is now in this article.
A countdown of the absolute best, most intense, craziest, messed up, and controversial Law And Order SVU episodes. How many full episodes with you watch in a row? Updated as of 2015, up to Season 16
Are you looking for some TV shows like 'The 100?' You have come to the right spot. I have compiled a list of some shows that offer the same type of narratives.
This list of the top 10 short Korean dramas is perfect for those of you who don't want to commit themselves to more than several hours to make it all the way through the story!
It's been seventeen years since The Fresh Prince of Bel-Air was first aired on NBC! Where are Will Smith, Alfonso Ribeiro, Tatyana Ali and the rest of the cast now?
45 short lived and easily forgotten television series from the 1970s. Plot line, actors, trivia, photos, videos and more! Take a walk down memory lane and see how many of these shows you remember!
The Office is one of the most popular shows ever, with 8.8/10 stars on IMDB.com. I love it and have watched every episode, which means I've noticed...inconsistencies. Read about them here!
With smoke monsters, time travel, ghosts and a mysterious tropical island, there's little chance that we'll come across a TV show like "Lost" ever again. But here's 10 shows that at least come close.
Westworld has been a huge hit with the audience and critiques from the get go. It's about time we looked at some other shows like Westworld while we wait for the next season to air.
The origin of the phrase "million dollar question" is linked to two 20th century TV quiz shows. Learn more about how these words became a common catchphrase.
Are you looking for some good TV shows like Breaking Bad to fill the void? You have come to the right place. I have put together a list of some similar shows that will hook you.
Check out this list of the top 22 Chinese historical dramas for you to watch! This list will be helpful not only for fans of Chinese period dramas but also for newbies!
Here's the list of the top 15 most popular, best, and greatest Korean dramas! Even if you're already a K-drama addict, this list will help you to increase your obsession. You can also watch trailers for some of the series here and vote in the poll for your favorite!
"Tanked" is a show that gives Animal Planet good ratings, but what message is it sending? I will review the show as well as its potential negative impacts on the aquarium hobby.
Running Man is an incredible show with a hilarious cast and tons of great episodes. Find out the funniest and most epic ones right here.
Discover the best alternatives to satellite TV and cable and and learn how you can save money and still see your favorite shows!
Singer Nat King Cole was the first African American to host a top flight network TV variety show. But after 13 months, it was canceled because no national sponsor was ever found.
Are you looking for TV shows like The Flash? You've come to the right place. Let's take a look at some similar shows.
Many have been taken with WGN's hit television show Salem, based loosely on the infamous Salem witchcraft trials of the 1600s. But is the witchcraft in the show completely made up or based in truth?
What a long strange journey it has been, to watch every episode of Star Trek from the original series, through the Next Generation, Deep Space 9, and finally Voyager, not to mention all the Star Trek movies, and then to try and put everything chronologically so it makes sense for a newcomer to the series. It has been a labor of love for months, and I am proud to present here to you The non Trekkie's Guide to Star Trek.
Brooklyn Nine-Nine features Jake Peralta and Amy Santiago; two talented detectives with an intense workplace rivalry. However, as the seasons progress fans start to see the rivalry blossom into a relationship. This article lists the 10 most significant Jake and Amy episodes of Brooklyn Nine-Nine.
"Running Man," Korea's most popular Sunday variety program for over two years, has been slipping in the ratings. Here are the reasons why and what the show can do to bounce back.
Are you looking for some gritty TV shows like 'Teen Wolf?' I've got you covered with this list of recommendations.
Countdown ten awesome trivia bits you probably didn't know about television program Pretty Little Liars!
Some of the most beautiful portrayals of friendship can be found in Korean TV dramas. Here are 10 that you need to check out.
Are you looking for TV shows like Gossip Girl? You've landed on the right spot. Let's take a look at some of them.
Hell's Kitchen, in over a decade of its existence, has been host to dozens of talented chefs. Some of which have personalities that are so annoying and cringe-worthy that they are reviled.
Season 4 of Mad Men featured classic songs by the likes of Simon & Garfunkel, The Rolling Stones & Jim Reeves. This article attempts to list all the songs heard on the show in season 4.
Good evening, boils and ghouls! Take a look outside. See how the leaves have fallen? How the pumpkins have been carved? How everyone's suddenly cool with children accepting candy from strangers?
Viewers have wondered if contestants on "Big Brother" and "Celebrity Big Brother" get paid. Yes, they do. The amount they get paid depends on how long they stay in the house without being evicted.
If you have Netflix or Amazon accounts, or simply watch PBS, you can see some great British TV Crime shows. From somewhat comic to serious, start your investigation of the best of British TV tonight.
For many of us, watching soap operas has become one of life's little rituals - a way to unwind at the end of the day. Women, in particular, often become hooked on these long-running television series. Some cannot bear to miss a single episode,...
The regular members of Running Man have the best variety skills and it's hard to find celebrities that can match their timing. Still, there have been some stand-out guests. Here are the 10 best men!
List of best old and popular Doordarshan (DD) serials. Article dedicated to pre-1990s Indian TV shows that you enjoyed in your childhood. This is a massive list with some videos for you to enjoy.
My top 25 all-time favorite, best, and greatest Korean Dramas. Have you watched them all? Vote for your favorite K-Drama on the poll!
The TV series Survivor has seen its share of injuries and accidents through the years. Look here for a history of some of the worst accidents and injuries on Survivor. These injuries can come from competitions, infections and vicious wounds, just to name a few.
From a mysterious black judge to multiple cases that Mason actually lost, here are interesting facts about the Perry Mason TV series that most people don't know about.
Of the hundreds of Fast Forwards, Detours and Roadblocks on The Amazing Race, these are some that were the most memorable.
Are you looking for some TV shows like Spartacus? You've come to the right place. Let's take a look.
All about the best legal TV shows. Who were the best TV lawyers? What puts a legal TV show among the best? The best legal shows have great lawyers, cops and the best legal courtroom scenes.
From combat to comedy, here are the ten television series that took place during World War II and aired in the sixties—the "Golden Age" of World War II TV shows.
In October, Charmed will celebrate its twentieth anniversary. In honor of this major milestone, let's take a look at what the Charmed Ones and cast are up to now.
Silly me for thinking a sit-com about people like me could actually be enjoyable. While I enjoy Big Bang Theory sometimes, these are a few of my biggest problems with the show.
Are you looking for some TV shows like The Big Bang Theory? You've landed on the perfect spot. Let's take a look at some similar sitcoms.
Here's the list of the top 30 Korean historical dramas for you to watch! This list is perfect for both avid fans of Korean period dramas and newbies who know nothing about them!
So why did Animal Planet spend so much money creating this Hoax? It must of cost a lot of money for the special effects and hiring actors and script writers to do it. So what was their motivation?
28 short-lived and easily forgotten television series from the 1980s. Veteran actors and newcomer's alike have their share of "misfires"; Tim Conway, Jerry Reed, David Soul, Shaun Cassidy and more!
Japan is home to many romantic TV dramas that are so good, they gain accolades even outside of the country. However, there are shows that are good but don't get enough attention. Here's 10 of them.
There have been many bad chefs in the nearly two decades of Gordon Ramsay's show Hell's Kitchen. Here are five of the worst of the worst.
USA's unique crime-comedy show wrapped its 8th and final season up in early 2014. Whether you're a longtime fan or are thinking about watching, here are 12 of the best episodes "Psych" has to offer!
Are you looking for some good shows like Arrow while you wait for next season to begin airing? Take a look at some of the best shows I have complied for you.
Hell's Kitchen is a popular restaurant reality show hosted by Chef Gordon Ramsay. The winner wins an executive chef position. Here are 5 of the most beautiful contestants who have graced the show.
Countdown six moments suggesting the original Red Ranger's abilities exceed that of his Green-clad rival's!
Season 6 of Mad Men provided yet another excellent selection of songs from the 60s era. This article attempts to list all the songs heard on the show in season 6.
In recent years, TV talent shows have burst onto our screens with a vengeance. With most showing ordinary members of the public competing for a large monetary prize, they are only increasing in popularity. Simon Cowell's hugely popular UK X Factor...
Here are the top 16 best Korean dramas you need to watch right now! Vote for your favorite K-Drama on the poll and let everyone know about the series you like the most in the comment section below!
Not every female guest in Running Man does well and there are few that turn out to be total busts. That said, some are really fantastic. Here are 10 of the best female guests .
Are you a fan of Game of Thrones and need a new show to start binging over the holidays? I've got you covered with the list of 20 TV shows like Game of Thrones!


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1.0 / October 29, 2010
App Information Turkey Call / Turkey Caller
- App NameTurkey Call / Turkey Caller
- Package Nameappinventor.ai_nlantz79.TurkeyCaller
- UpdatedOctober 29, 2010
- File Size4.0M
- Requires AndroidAndroid 1.5 and up
- Version1.0
- DeveloperNick Lantz
- Installs100+
- PriceFree
- CategorySports
- Developer19 cartier rd London ontatio n5v1g4
- Google Play Link
Nick Lantz Show More...
Predator X 1.5 APK
Predator X is a Game caller for Predators suchas wolf, Coyotes and Foxes. This app comes stocked with 24 soundsto attract predators attention and bring them in close for a kill.Some of the sounds include "deer Distress" calls, Chickens, JackRabbit calls, Coyote Pup Distress calls and more. All sounds arearound 60 seconds long for a total of 24 minutes of sounds
Deer Caller 1.0 APK
Canadian Goose Call 1.0 APK
Moose Call 1.0 APK
Moose Caller is a mobile moose caller that comes with 8 cow calls,3 bull calls and a calf distress call. These calls are not loudenough to use in the field without an axillary speaker hooked intoyour phone, unless the moose is 50 yards away. It is useful forpractice to help call in that MONSTER MOOSE.
Turkey Call / Turkey Caller 1.0 APK


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Keep reading and listening and pick up inspiration. Stay up to date and deepen your knowledge about your niche. Read books and blogs about it. Listen to podcasts and watch videos. When you have new ideas flowing into your mind each week and month you'll come with new stuff yourself. Or combine what you have learned. Or you can share your experience with what you learned from someone else.
Before I looked down to see who the creator of the pin was, I knew it was going to be from Pauline Cabrera over at twelveskip.com. Without even realizing it, I had subconsciously begun to recognize her purple-themed pins with the crisp block font. And I knew that those pins led to really good content, so I clicked on the pin and ended up reading her article.
One of the important aspects that you should look for is the uptime of the provider. Search around and see if there have been any major problems associated with that hosting provider. Search for reviews and decide on the price point you're willing to spend. You should also ensure that the hosting provider has a WordPress plugin if you're not all too familiar with setting up software such as WordPress on a hosting account.
More often than not, people think they should blog about popular topics where they think money grows on trees. And while the truth is that you might be able to attract the larger audience if you write about smartphones instead of blogging about something specific like tuna fishing, that's the wrong way to go. In the case, it would show that you write about something you might not completely understand and love, and it would result in an unsuccessful blog that not even you would enjoy.
Edit yourself. We know you're ready to click "publish," but take a minute to self-edit your work. (The Write Life has some great self-editing tips.) If it's laced with errors, you're going to lose credibility — and readers. Recruit a friend or family member to have a second look. If no one's available, read your work aloud. This is a great way to view it from a different angle and identify areas that need polishing.
Lets say, for example, that you refurbish and resell used smartphones out of your home. You could use a blog to attract visitors to your website where you list your current phones for sale. Your blog might cover topics about DIY refurbishing. On one level, it seems counterintuitive because you want people to buy your phones, but it also helps you build a brand and gain recognition. Social media guru Jay Baer explains the concept on Copyblogger:


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Make This Your Special Spot For Relaxing Unless...
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Make This Your Special Spot For Relaxing Unless You Prefer To Catch The Breeze By The Pool On The Large Outdoor Deck. Nice Water Feature Adds To Pool Side Ambiance. Space For Two Personal Watercraft In Addition To Boat Slip. Situated On A Peaceful...


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I took the plunge and signed up for 99Designs. I have already submitted 2 designs in my spare time. Now, in middle school and high school I was into art pretty hardcore. But my love from computers caused me to put down the pencil and pick up the keyboard. I am glad to find something that has gets me drawing again, and can earn me a bit on the side. Thanks again!
If you want to help shape products in their early stages, joining an online focus group or answering survey questions is a great way to make extra money online. They don't pay as much as some of the other options we've highlighted, but you can join groups on sites like Survey Junkie, Swagbucks, and IPSOS that pay out through Amazon gift cards, check, or PayPal. You'll be asked to provide a bit of information about your demographics (age, location, etc…), but after that you can get going making money through surveys.
One of the cool things about Google AdSense is that it's so easy to get set up. If you have a blog or website, you can sign up for a free Google AdSense Account. From there, Google will give you a unique code that you will paste onto your website. Google takes it from there, tracking your page views, traffic, and earnings on your behalf. There is no upkeep or maintenance to get this thing going, which makes it a no-brainer if you have a website already.
Get your Blank ATM DEBIT CARDS that works in all ATM machines, "Infinity Cards" has programmed some Cards that makes you withdraw money free from any ATM machines, Transfer, At Store. Min/Max daily withdraw – $5,000/$20,000, We sell the cards to Interested buyers, contact us on firstname.lastname@example.com or +19402266645, to get full details & the cards.
I make good money thieving. I only work a few hours a night, and you can make anything from a few hundred quid to a few thousand quid. You've got to have a bit of bottle and be able to look after yourself. If you think you've got thr guts to do it? I highly recommend it, I mean it's got to be better that spending hour after hour on a PC, making small chance, how boring is that?
Your money is either in charge of you or you're in charge of it, there's no middle ground. Using some type of personal finance software can help alleviate some of that money stress and better allow you to manage your money effectively. Without it, you may just be setting yourself up for constant financial worry. Life is already tough enough and there's no need to make it more difficult by simply hoping your money issues will all work out in your favor. Hint: they won't.
The cash back industry is ruthlessly competitive, isn't it!? All of these apps want new users, which means you can load up on welcome bonuses. The Ibotta app is another opportunity to get a bonus: they are giving people $10 when they sign up. Unlike the other apps mentioned in this article, Ibotta specializes in getting you cash back at grocery stores.
Matched Betting (not available in the USA) enables you to gamble (nearly) risk-free. I say nearly as there is always room for error! It involves placing bets on all outcomes of an event, using free online bets given out by the Bookies. Although it may take a while to get your head around the concept, Matched Betting can make a substantial addition to your monthly income.
Hold a yard sale. If you have a yard or garage and plenty of items to sell, you can have a yard sale as early as tomorrow. By advertising your sale on local Facebook pages and Craigslist, you can also skip the paid newspaper ad and keep all of the profits for yourself. If you don't have time to price everything, try asking patrons to "make an offer" or grouping similar items on tables with an advertised price (e.g. everything on this table is $5).
Outsourcing is the new and dominant wave of the business world. As businesses shed employees, they increasingly turn to independent contractors to supply what in-house staff used to do. One of the ways they do this is through virtual assistants. These are people who provide certain tasks online. Businesses can use virtual assistants as much or as little as they need to. If you can make yourself available to multiple businesses, you might have plenty of work without ever leaving your house.
21. Facebook – Facebook swap shops are great for selling things locally. It's like CraigsList, but a little easier. You simply search for swap shops in your area and ask to join the group. Once you're in, take a picture of the item, write a quick description with the price and post it. It doesn't get much easier than that. You can generally expect to get about what you would get at a yard sale, maybe a little more.
What these opportunities typically turn up to be is a pyramid scheme. You pay a fee to signup. You then receive a flyer saying how great stuffing envelopes is and list of names and addresses to mail said flyer. IF those people pay that signup fee so they can mail that flyer too, you get paid a small referral fee. ONLY if they take the bait do you get paid.
Rather than making money through subscriptions, YouTube channels are based on a traditional advertising system. Meaning the more viewers you get, the more you make. Once you're approved for the YouTube Partner Program and can start including ads on your videos, with every 1,000 views, you will make approximately $2-$4. Which might not seem like a lot, but if you have 100 videos with 5,000 views a month each, that would be $1,000–$2,000 already. Just imagine if your videos start hitting millions of views!
Writing copy for websites is another great freelancing option for those who have a way with words. Copywriting can involve writing the text for websites, press releases, promotional offline materials including leaflets and brochures, and any other professional text for businesses. While writing blog posts is well paid it won't make you as much money as writing copy for sales pages. However, clients can be more fussy, as they want the highest quality writing for the forefront of their website or advertising campaigns. Many freelance writers offer both copywriting and blog writing amongst their services. This can be a good way to juggle regular but lower paid clients (blogging) with the higher paid but ad-hoc project based copy work.
Webinars On Air is a powerful webinar tool that will enable you to create professional webinars for your viewers. Harnessing the power of Google Hangouts, this all in one solution will take care of all the technical aspects of hosting a webinar, including payments. Also have a look at our guide to the best webinar software, both free and paid options.
Get-rich-quick schemes and fad weight-loss diets are naturally popular because they satisfy the id while also attending to the super-ego. The ego's job is complete when it sees something like this. The appeal of "fast'' stems from the innate desire for instant gratification, so beware of what seems too good to be true (they often are) when you're looking to make money quickly. Be wary. Listen to the conversation deep within the confines of your mind and do your best to tame the proverbial beasts.
If you're running on fumes, financially speaking, but you have some money coming your way soon, consider pawning something of value to borrow fast cash. Of course, to get those items back you'll need to pay back the loan with interest. If you don't pay it back in time, that you'll lose the item. If it's really something that has a lot of intrinsic value to you, don't do it. But if it's something that doesn't, you can certainly consider it depending on your situation.
Selling digital products can be just as successful as selling physical products. Graphics, software, eBooks, design elements, sound effects, songs, and videos are just a few types of digital products that are in popular demand. So if you can turn your hand to creating digital products, let's have a look at how you can make money online from this skill…
One should think about their skills, hobbies and basic daily habits as well. Do you like to cook? Be a personal cook or dinner parties. Baking? Make wedding cakes or cupcakes for weddings/special events. Do you enjoy cleaning? Trying going to banks/repo companies and ask if they are in need of a repo cleaner or market yourself as a all-around cleaner. Know how to mow a lawn? Get paid to do it in your neighborhood. Sell products from large companies – Jewelry in a candle, Sentsy, Health and home products – etc.
Whether it's an important consumer application, a specialist app to solve a particular niche problem, or even a time-wasting game you can play on your phone, you can create a massively successful business if you build software that helps people. (Look at the rise of Slack—the team communication software that went from side project to billion-dollar company in just 2 years.)
It's sometimes hard to comprehend just how much people love t-shirts. And with the right niche, marketing, and tools, you can create an online t-shirt business that makes you extra money online while you sleep. (Even Bloomberg and Forbes feature stories from entrepreneurs who've done just that.) Services like TeeSpring make it easier than ever to create a t-shirt drop-shipping business where they handle the sales, printing, and shipping, and you're only responsible for design and marketing. For more tips, check out this simple guide to launching and marketing an online clothing store by my friends over at Selz.
Whether you want to become your own boss, start a side hustle, or earn extra money on the side, any of the strategies listed above can help. By finding ways to increase your income, you can free up more cash to pay down debt, save for the future, or invest for retirement. Saving money is only half of the equation. And if you truly want to get ahead, you might want to figure out how to make money – and hopefully, lots of it.
Ebates has long been one of my favorite services and they offer an awesome referral program. This service pays members cash back on their online purchases – and some in-store purchases now. When you refer your friends, you will earn $5 per person when they make their first purchase of $25 or more. They also offer some stellar bonuses if you can refer a number of people. And, they offer a $10 gift card for new members.
Many new users prefer to start off with the 100% Free Offers, which is what we usually recommend. These offers are great for beginners because nothing is required other than several minutes of your time. The payouts on these offers are lower, but you're not paying a dime to complete them and they'll get you use to the CashCrate system. After you've started making money online with our free offers, you can always move on to trial offers and increase your earnings.
You can sell your ebooks through Amazon's Kindle program or Apple's iTunes Connect, which gives you access to a large majority of the digital-book reading market and the barriers for entry are incredibly low. You don't need to invest lots of money to make this happen, but you do need to invest lots of time, not only in writing the ebooks, but in marketing them as well.
Yaro, I appreciate your work and selfless effort to help others by publishing your experiences and money making advise. This article is a masterpiece. I recently sent you an invitation to connect on LinkedIn. And, after reading about your interest to develop personally (I assume professionally as well), I would like to share my life's work and experiences on the topic.
Great list! I have another to consider that I personally have 35+ years experience providing. Clean up litter outside commercial properties on foot using inexpensive hand tools. It's almost as easy to do as going for a walk! I started doing this as a side gig in 1981 and soon grew it into a profitable full-time business. I share my experience in my book, Cleanlots.
A spin-off for web designers is to offer a landing page creation service. Well-optimized landing pages can be the difference between a successful and a failing business. And, as creating the perfect landing page isn't easy, this is a service many businesses are prepared to pay for. I know people who are earning 6 figures per year and all they do is create landing pages for businesses. There's serious money to be made.
You can sell product from your own website store, via community sites and classifieds (like Craigslist) and of course eBay and collectively make good money. The challenge, like with any business, is defining what is your competitive advantage and can you come up with a model that meets your needs. For me selling physical product was a great proving ground, but I eventually learned that profiting from information was a preferable model if I wanted to meet my aforementioned business goals.
Hello I am 26 and just hit a huge life crisis wall! I had a great job and was let go out of the blue, with little to no money left for bills and other.. I was scheduled to drive home from Florida to Michigan tomorrow with my boyfriend and he has no idea I have only $400 to my name I have no idea what to do or how to get enough money to get me through this trip.. I already have found a new job but I don't start until we are back in 10 days ! I feel like I am so underwater!
This post took approximately 6 hours to compile, including research. I'd appreciate it if you would support my efforts by Stumbling this post, bookmarking it on Delicious, and Digging it. Finally, if you are not already receiving my free business tips, jump on board! Every week I'll send you a thought-provoking post about how to build your business and make more money. You won't want to miss what I have in store for you… Get my free business tips!
To advertise my tutoring service I marketed using posters offline and eventually set up a website and marketed on classified sites as well. I charged $15 an hour and eventually had a few Korean clients. This idea eventually ballooned into a full on English school with a real world premises that I managed for eight months before closing down. It turned out to be an experiment that taught me I much preferred online business to bricks and mortar.
I just started a blog and was hoping to move into affiliate marketing soon. However, I am not really sure how I feel about the layout and its functionality. This might be a little bit spammy and I apologize but I'm looking for some feedback on the layout of the site. If you guys could check it out and leave a comment somewhere I would greatly appreciate it! Thank you!
So, I put together a free master course for you to take that spreads out all of the work involved in starting a blog, into a series of action-packed lessons. My free course breaks the entire process of starting a blog down into an incredibly simple 7-day process for going from 0 to publishing (and promoting) your first blog post in just 1 week. I can't recommend it enough.
If you are a creative type, then you could make money online by designing and selling crafty products on Etsy. Etsy sells a range of beautiful and original items from independent suppliers. Categories range from jewelry, clothes, and accessories, to art, collectibles, and vintage. So if you have some stunning crafty creations, Etsy is the perfect platform from which to sell from.
If you have nothing of value to sell from home then retail arbitrage might be a better option for you. Many people partake in arbitrage to earn a little extra money, and for some, it has even become their full-time job. Retail arbitrage is the buying of goods at a low price and then selling them on a different platform at a higher price. Sales in shops provide ideal opportunities to pick up products for next to nothing. These can then be sold on eBay or Amazon for higher amounts, making you a nice profit.
If you live in an area where Uber or Lyft operate, why not become a driver? If you're looking to make some short-term cash, you can definitely rake it in by working for one of these popular car-hire apps. As long as your vehicle fits within the specifications of their program, and you have a clean license, you could do this on the side, especially if you're in a crunch for cash.
This post took approximately 6 hours to compile, including research. I'd appreciate it if you would support my efforts by Stumbling this post, bookmarking it on Delicious, and Digging it. Finally, if you are not already receiving my free business tips, jump on board! Every week I'll send you a thought-provoking post about how to build your business and make more money. You won't want to miss what I have in store for you… Get my free business tips!
It shouldn't come as a surprise, but people who regularly monitor their finances end up wealthier than those who don't. When you were a kid, keeping track of all of your money in a porcelain piggy bank was pretty easy. As we get older, though, our money becomes spread out across things like car payments, mortgages, retirement funds, taxes, and other investments and debts. All of these things make keeping track of our money a lot more complicated.
Not very exciting work, but in high demand from bloggers and small businesses. This involves setting up accounts on all of the social bookmarking services and then bookmarking your clients' websites or latest blog posts to help them get more traffic. You may be competing against software that does this, but in many folks' opinions, it's better to have a real person do it. Even better is if you can goose your accounts with plenty of friends and become a star on a few of the services; then every site you bookmark has higher credibility and you can charge more. To get an idea of the social media sites you will need to sign up for, start at socialmarker.com.
I really don't want to chat, receive or make calls (I have a kid and baby I don't have no silent place to work and also because I'm not a calm person I get mad easily fast), I don't want to go out at my home because of doing a "job", don't want to do survey, I don't want to write or share my thoughts or anything like that, I don't want sell anything either.
Finally, when looking around for the right personal finance software that meets your needs, make sure that you're comfortable with the program's interface. It shouldn't be expected that you recognize every single feature instantly, but if the features don't seem readable and manageable to you, then you're not as likely to use it and get the full benefits.
Acorns rounds up your everyday credit and debit transactions and automatically invests the spare change for you. It's only $1 a month and free for college students with an .edu address for up to four years from the date of registration. You'll barely notice the micro-investments of spare change, plus the Found Money feature invests money in your account when you shop with Acorns partners such as Macy's, Nordstrom, and Walmart.
Yaro, I appreciate your work and selfless effort to help others by publishing your experiences and money making advise. This article is a masterpiece. I recently sent you an invitation to connect on LinkedIn. And, after reading about your interest to develop personally (I assume professionally as well), I would like to share my life's work and experiences on the topic.
I'm a huge fan of blogging because I love writing and connecting with people all over the world. To give you an idea of what is possible with blogging, DollarSprout.com is part of a group of blogs that routinely brings in over $100,000 a month in revenue. While it takes time to build your blog up to that income level, you can get the initial set up done in under 30 minutes (no experience needed).
Freelance writing is such a great industry to get involved in if you want to work remotely. There's plenty of work available and it's typically one of the most flexible gigs in terms of scheduling. (You can often do the work whenever and wherever you choose.) Even better, it's pretty easy to get started with a degree or previous writing experience. Read more at Freelance Writing Jobs for Beginners
One more thing, In order to make money with sponsoring, you need to advertise which can get costly. I try to do as much as I can by posting ad for free. Google search for "free ads" or "free ad post" and you will get hundreds of places to post a free ad. Some work quite well, some don't. But they do work. I also have great places to find leads for free and even profit from it. Here is some places to find free leads.
Amazon will have you work on micro-projects that require some sort of human interaction. Tasks can include translating a paragraph into English (or another language), rating the search results for certain keywords, or reworking an article. The tasks are simple, and you will be paid a small amount to complete each. But if you do enough tasks quickly, you can make a respectable amount of money.