text:
Collaborative Divorce Lawyer Roswell, NM
Are you looking for a collaborative divorce lawyer to work with in Roswell? Give our firm a call today at (505) 796-6238. Here at Atkinson & Kelsey, P.A., we will be able to help you no matter what unique aspects your collaborative divorce case has.
A collaborative divorce process by its nature is a dramatic change in the client's life, but Atkinson & Kelsey, P.A. has all the resources necessary for you to adjust to this change. Our network of other professionals and services in Roswell can help you get the most out of your collaborative divorce case when represented by us.
At Atkinson & Kelsey, P.A., our legal team knows that collaborative divorce matters can take a heavy emotional toll. Over our many years of experience working in the area, we have seen plenty of unique cases and circumstances, and we have always listened to our Roswell clients so we can understand what their definition of success is.
When you find yourself in the midst of a collaborative divorce dispute in the Roswell area, there is an immediate need to decide how to respond to the situation. Do you take matters into your own hands and hope for the best, or do you seek professional collaborative divorce guidance to inform your decision? Do not wait for your collaborative divorce case to spiral out of your control. Give us at Atkinson & Kelsey, P.A. a call today at (505) 796-6238.
Atkinson & Kelsey, P.A.
2155 Louisiana Blvd NE
(505) 796-6238


text:
Old Home Wiring Colors Wiring Schematics Diagram Old House Electrical Wiring Colors Gallery Wiring Diagram Old Tv Colors Old Home Wiring Colors Electrical Wire Colors #6483
Executing electrical wiring by yourself is often tricky. This is certainly specifically so once you absence the know-how as well as knowledge in electrical stuff. The factor is you can not do a trial and mistake system when dealing with electrical wiring. Issues could price tag you a fortune or even your lifetime. That is why prior to starting off any do-it-yourself electrical repair, you need to question some electrical wiring issues only to be certain you are aware of what you're doing. One thing about electrical wiring is the fact wires are usually shade coded. So, it can be actually simpler to understand which of them go with which. Under are the commonest electrical wiring inquiries whose answers commonly require shades to help you identify each individual wire. - Home Depot Electrical Wire Connectors
Simple Home Electrical Wiring Diagram Allove Me Electrical Wiring Diagram Pdf New Simple Home For Home Electrical Wiring Diagrams #2731
Circuit Diagrams The Current That Flows In An Electric Circuit Carries #4141
How can You Wire a Switch?
One of by far the most frequent electrical wiring queries is regarding how to wire a switch. Although making use of switches in your own home is fairly straightforward, wiring just one may well not be that uncomplicated for everybody. An ON-OFF switch is in fact quite simple to wire. You will find several types of switches, but for this example, let's say you might be installing a single-pole toggle switch, a very widespread change (and the simplest).
There are three colours of wires inside a common single-pole toggle switch: black, white, and inexperienced. Splice the black wire in two and hook up them over the terminal screws - one particular on best as well as other around the bottom screw on the swap. The white wire serves as being a resource of uninterrupted energy and is also usually linked into a mild colored terminal screw (e.g., silver). Join the eco-friendly wire to the ground screw of your respective switch.
These measures would commonly be sufficient to create a standard switch get the job done with out a problem. Nevertheless, in case you are usually not confident that you simply can complete the endeavor appropriately and properly you greater permit the professionals do it as a substitute. After all, there is a purpose why this job is without doubt one of the commonest electrical wiring inquiries requested by a lot of people.
How can You Wire a Ceiling Fan?
For some reason, the best way to wire a ceiling fan can also be one among one of the most common electrical wiring thoughts. To simplify this undertaking, you should use an individual change for the single ceiling fan. To wire the lover, it can be merely a make any difference of connecting the black wire with the ceiling fan to your black wire of your switch. If there is a lightweight, the blue wire must be connected to the black wire of the swap too.
How do You Switch a Breaker and how Do you Incorporate a Sub Panel?
Whilst lots of attempt to perform these duties on their own, the majority of people are suggested to hire an electrician as a substitute. It can be more sophisticated and therefore risky for many men and women to test to exchange a breaker or include a panel. To provide you with an plan about such common electrical wiring inquiries, you would have to perform on the warm electrical panel. Should you never even determine what what this means is, you might be only not geared up to try and do the task oneself. Even though you really have to shell out extra by selecting a specialist electrician, it is really a lot safer and a lot more practical to carry out this as a substitute. - Old Home Wiring Colors Wiring Schematics Diagram Old House Electrical Wiring Colors Gallery Wiring Diagram Old Tv Colors Old Home Wiring Colors Electrical Wire Colors #6483
There are actually causes why they're probably the most commonly requested electrical wiring inquiries. One particular, numerous consider it is straightforward to try and do, and two, these are definitely the frequent electrical responsibilities in your house. But then you really shouldn't place your security in danger with your intention to save cash. The stakes could even be a lot larger in case you try to save money and do an electrical wiring career without the need of adequate understanding or knowledge.
Tablets | iPad HD resolutions: 2048 x 2048
iPhone 5 5S resolutions: 640 x 1136
iPhone 6 6S resolutions: 750 x 1334
iPhone 6/6S Plus 7 Plus 8 Plus resolutions: 1080 x 1920
Android Mobiles HD resolutions: 360 x 640 , 540 x 960 , 720 x 1280
Android Mobiles Full HD resolutions: 1080 x 1920
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Ultra HD 8K resolutions: 7680 x 4320

subset: commoncrawl


text:
Which Indian cricketer is known as "Brown Bradman"?
Which of the countries has had a prime minister whose name featured the name of his country?
Which of the gulf city was a dependency of Bombay Presidency under British rule for almost a century?
Who claimed to be a direct descendant of King Solomon and the Queen of Sheba, and worked to achieve the..............
World War I was triggered as a full-blown war when the United Kingdom declared.......when Germany invaded which country?
A spaceport known as CSG and used by the European Space Agency (ESA), the French space agency CNES..................
RRC ASN1 related
How size of RLC buffer is determined ? what will be size ? when buffer will be completed ?
Trans continentel stuart highway connects
What is muladhara in vastu?
How many runs a single player can score in One day match (50 overs/ 300 balls)... No 'no balls', no wides, no extras, no over throws.So how much runs he can score max?
In last over player can score 36 runs and in all previous overs player need to have 5 sixes and 3 runs in the last ball to retain the strike so in total -
49*33 + 36 = 1653
He does this for all the 50 overs, that makes 33*50 = 1650 runs.
Just that on the last ball of the match, he doesn't need to take 3 runs and can hit that for a six too. That adds 3 more runs to the tally and makes his total as 1650+3 = 1653 runs.
FIRST 49 0ver he can score about 49*33 (5*6=30 and 1*3=3 total 33)
last over 6*6=36
33*49 = 1617
6*6 = 36
As per Jayanth Raj Gowda it comes to 49*35+36=1751. I don't know what is wrong in it.
31*50 = 1550 + 5 =1555
3 runs reqd in 2 balls to win with only one wicket left. The batsman is on 98 and the non striker is on 97.
How will both batsman score centuries as well as win the match without extra ball?
Shikhar Dhawan and Virat Kohli were batting on 94. Seven runs were required to win by the team and only three balls were left.
At the end, both of them secured a century without being out. How can this be feasible?
It is a strange cricket match in which batsman is getting bowled in the very first ball he faced. Assuming no extras in the match, which batsman will be not out at the end of the inning ?
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text:
Athena karkanis dating
She also appeared in direct-to-video action films The Art of War II: Betrayal (2008), and Sacrifice (2011).Actress Athena Karkanis got her start in acting in the early 2000s.She made her acting debut in an episode of 1-800-Missing, which aired in 2005; two years prior to that, however, her voice was used in an episode of the sketch show Chappelle's Show. I was brushing my hair and cleaning up, until I heard a siren, I walked out and Chris was on top of the roof. " Chris said "Today we have a very special treat" He said. " Scott had an excited look on his face "Helicopter bear hunt? I had no idea he actually can get excited over that. "From now on, it's every man, woman, and Cameron to themselves" He said walking over to Lightning, Jo, and I. Now I only have to worry about me, myself, and I, but I don't know if Scott thinks that just because were dating that means we are sticking with each other till the end, I mean like yeah, but no way am I being his ally, I don't trust him, even if he is my boyfriend, I think I will just stick to Zoey, Mike, and Cam.// Chris took out his walkie-talkie. "You crushed our cabin with a large concrete block?! "I had a bunch left over from building a monument for myself" Chris said "I call it Mount Chirsmore! "From now on you'll all share this tiny, cruddy little cabin" Chris said.
Athena karkanis dating comments


text:
Compass points to legal success
A student on Birkbeck's pioneering Compass Project, which helps refugees and asylum seeking communities access educational opportunities in the UK, has been awarded the prize for Best Essay on the CertHE Legal Method at the College's School of Law Awards.
Young filmmakers highlight the role of 'hidden persuasion' in everyday life
Birkbeck's Hidden Persuaders research group has worked with students from three London schools to create films exploring influence and brainwashing – four of which will feature at the BFI's Future Film Festival.
Jews, Money, Myth: Birkbeck academics contribute to major new exhibition
The Pears Institute for the study of Antisemitism at Birkbeck has collaborated with the Jewish Museum on a major new exhibition exploring the stereotypes that link Jews and money - how they have evolved in different political contexts and how they have been exploited for different ends.
Leonardo da Vinci and Perpetual Motion: Visualising Impossible Machines
Birkbeck 43 Gordon Square
Arts Programme: Cultures & Languages - Industry Taster - Postgrad focus
Birkbeck Main Building
Arts Programme: Cultures & Languages - Industry Taster - Postgrad focus
Birkbeck Main Building
What is Global History?
Professor Julia Lovell explains how the discipline of Global History was developed to reach across national boundaries; and how it can help us understand this current era of unprecedented globalisation.
What we talk about when we talk about whistleblowing
Whistleblowing is a hot topic from Hollywood to Canary Wharf. But have you ever stopped to think about how we 'talk' about whistleblowing? Which words do we choose and why?
The Birkbeck experience
Birkbeck is different: our classes are held in the evening, so your days are free - to study, work, volunteer or just do your own thing.
Life at Birkbeck
Birkbeck offers a unique combination of evening study and a matchless central London location, right in the geographic and academic centre of the city, giving you exceptional opportunities.
Research with impact
Discover how Birkbeck's socially engaged research informs public policy, pushes scientific, medical and technological advances, supports the economy, promotes culture and the arts and makes a positive difference to society.
Careers and employability
Our free Careers and Employability Service provides comprehensive careers advice, events and information services for current students, both in person and online, and for recent Birkbeck graduates.
Schools and departments
Birkbeck's five distinct schools cover a range of academic disciplines, each providing a stimulating and dynamic environment for learning and research.
Evening study explained
Birkbeck is London's only specialist provider of evening higher education. With classes held 6pm-9pm, your days are free to study, work, volunteer, or just do your own thing.


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Appstamatic.com has a Worldwide ranking of n/a Down n/a and ranking n/a in n/a. Using IP address 184.108.40.206 in and found 10 Other Websites on this Server
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Guide for iCloud. Storing all your data on the cloud allows you to access your documents, apps, photos or music on any of your Apple devices. If you break your phone, you can access all your stuff again on a new phone or on your laptop just by logging into your iCloud account!
Link: http://www.appstamatic.com/ (Actived: Monday Feb 11, 2019)
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text:
SOURCE: Netsoft USA
September 11, 2008 17:08 ET
Experienced Technology Marketing Executive Brings Market Development Initiatives to Netsoft USA
NEW YORK, NY--(Marketwire - September 11, 2008) - Netsoft USA, an acknowledged leader in
enterprise application development for life sciences, financial services,
and distribution and supply chain, today announced the addition of David Z
Orban as vice president of marketing. Orban brings more than 20 years of
marketing leadership and market development experience to his role at
Netsoft USA. He will focus on the development of strategic initiatives
relating to market growth and serving the company's client base.
"Dave Orban brings a solid track record of building successful marketing
strategies and developing new market segments," says Arto Ozgun, co-founder
and president of Netsoft USA. "We're pleased to welcome him to the Netsoft
USA team and look forward to leveraging his expertise and leadership in
support of the delivery of our next generation of enterprise solutions to
the market."
Orban's diverse background spans the enterprise solutions space, including
leading the launch of several technology startups. Orban is the former
director of marketing for Muze Inc., where he led the company's rebranding
and the successful introduction of new channel programs and client-facing
initiatives. Prior to that, as director of marketing at Actimize, Orban
launched market- and client-facing initiatives that drove profitability and
growth for that company. Orban has held similar roles at Albridge Solutions
and Princeton Financial Systems, as well as having been a technology
marketing consultant to the scientific publishing industry.
"Netsoft USA has a substantial history of providing distinct value to the
market for custom enterprise applications. I look forward to working with
the management team to deliver high value enablement solutions to our
clients, using our unique development framework," said Orban. He added,
"Netsoft USA is an exciting company operating in a dynamic set of markets,
and I'm extremely pleased to have the opportunity to engage with a
world-class client base as part of the management team."
About Netsoft USA
Established in 1999, Netsoft USA is a technology services company
headquartered in New York City, with operations in Toronto and Armenia.
With extensive industry expertise in financial services, healthcare,
distribution and life sciences, Netsoft USA provides smart technology
solutions that make businesses perform better. Organizations worldwide rely
on Netsoft USA's proprietary Solutions Roadmap and Solutions Framework to
gain a competitive advantage and achieve extraordinary results. To learn
more, please visit http://www.netsoft-usa.com.
Press Contact:David Z OrbanVice President of MarketingNetsoft USA212 994 8181 x 129Email Contact
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text:
Included in every room:
- Enclosed balcony overlooking lake
- Private shower/bath/toilet
- Airconditioning
- Toiletries (towels, handsoap, bodysoap, shampoo, and rinse)
- Free WiFi
Available at additional charge:
- Use of laundry machines
Room Services
Included with every room:
- Periodic towel replacement and room cleaning service.
Food Services
- Breakfast (buffet style).
Bar Services
- Softdrinks, coffee, and alcohol.
Nojiri Lake Resort is located right in the middle of various famous ski slopes. In almost every direction from the hotel there is a ski slope within 10 to 20 minutes by car. Last season the Resort was full of all sorts of interesting people during this season; beginner skiiers, professional skiiers, families with kids needing extra support for beginners, people just wanting to get into the snow, and on and on.
For those wanting to go skiing/snowboarding, the Resort can help you in the following ways:
- Rental equipment: We can help you get the equipment you need for skiing and/or snowboarding. This equipment includes, skis, snowboards, boots and other related equipment, clothing; jackets, gloves, hats ect. View price chart.
- Lift Tickets:
- Every year ticket prices vary with special package deals. Ask us about them.
- Each slope has its own price list, as about these as well.
- Transportation to the slopes:
- If you have your own vehicle then all you will need are directions. Ask us.
- Those without vehicles need not to worry, the Resort has a "go and come" pick-up service. We will get you to the slopes and pick you up. And, many times this vehicles circles around and allows stops at the local 7/11 and/or restaurants for special request by individuals. There is a 500 yen fee/day for this, and it does require some advanced notice so staff can plan for it. (These "go and come" pick-ups are for the following slopes; Akakura, Ikenodaira, Suginohara, Kurohime, Tangram, Madarao. Also, the times fluctuate depending on road conditions and numbers of people at each location.)
PowderHounds is also a great resource for finding ski slopes in the area, with up-to-date information regarding snow conditions, difficulty level, directions, etc.
For those guests wanting to borrow a bicycle for a short ride up to the 7/11 or even a ride around the Lake, the Resort may be able to help you with our fleet of bicycles. Please ask at the front desk for times and availability.
The bicycles will require your checking the brakes, adjusting the seats, and maybe even putting air in the tires. They are not brand new, so any one borrowing them needs to understand that there may be some difficulties.
Those that borrow them understand the following:
- The bicycles and any equipment related to them, will be replaced to the original location when finished using them.
- Any damage to the bicycles will be the responsibility of the borrower.
- The Resort can not be responsible for any damage or accidents when using the bicycles.
Nojiri Lake is quite well known for its sports fishing. There are various types of fish in the lake.
In the summer "Black Bass" is definitely the most sought after. There are other fish as well, in this season such as trout. There are two means for fishing these Bass, the first is to rent a boat, and the second is fishing from the side of the lake. Those people wishing to rent a boat will then need to decide what level of boat they want and/or will be allowed to rent. Boats that need licenses are the ones with motors, while boats that are paddled or peddled can be rented without a license. Rates for these depend on the Rental Fishing Boat companies that can be found all around the waterfront. Also, for those that don't have equipment, this can be rented as well. Please ask at the front desk for which company is legally operated.
In the winter, "Wakasagi" is pretty much the only fishing excitement on the lake. This fish is fished in large heated boats that have troughs open into the lake water on both sides of the inner room of the boat. The person fishing will sit on a straw mat a good number of other participants, and extend their miniature fishing rod over the trough so that the bait may drop into the lake water. Wakasagi are known for being a delicacy in Japan, however, they are very small, so anyone looking for reeling in a gigantic catch may find this sport "different". Also, the boats leave early in the morning from the various piers and don't return until 3:30 in the afternoon, unless the boat owner has made special arrangements with you.
- You MUST purchase a daily fishing license!
- If you are out on a boat all day you may get sun-burned, be prepared.
Ask at the front desk for more information. Nojiri Lake Resort does not rent any fishing equipment but we do know where to go to get started.
Immersion English Offsite Experience
A Program for enhancement of business workers' English-language & intercultural communication skills.
- To offer an English-language immersion program that meets corporate needs for enhancement of English-speaking capabilities
- To deliver such a program in the attractive natural surroundings of Nojiri-ko and the Myoko/Kurohime area, as a destination for off-site training within Japan, with minimum travel distance from Tokyo
- To provide an "all-in" package including: accommodations, meals, local transportation, recreational activities, professional training content, & instructional materials in English
- To create a "value-add" experience based on an opportunity to practice English, with optional units including: Diversity, Team- Building, Group-Dynamics, Intercultural, & Leadership Training.
Mission & Objective
- That each individual participant will benefit from the opportunity to participate in an English-language environment, will raise their "comfort level" to be able to express themselves without hesitation, and will enjoy their experience, combining in-class with outdoor activities, in a memorable opportunity to raise confidence in their own ability to communicate in English.
- That corporate sponsors will see improvements not only in their participants' comfort level in English communication, but will see an impact on team-work, group dynamics, & improved group morale.
Instructional Leadership
- Lee106 Holdings (with its affiliate firms Lee106 & Lee106 Academy) will provide qualified & experienced professionals as facilitators of all events, with native English-speaking instructors and trainers
- Project Coordinator & Lead Facilitator will be Dr. David Satterwhite, former Exec. Director of Fulbright Japan, current adjunct faculty at Temple University Japan (TUJ) and Waseda University
- Project Team Members include: Mr. Thomas Carrick, Managing Director of Lee106, & Mr. Ted Skillman, Managing Director of Lee106 Holdings, providing institutional & instructional support
- Mr. Skillman taught for 14 yrs at the Gakushuin Peers School, was affiliated with the Ministry of Education's Accredited Textbook Production for numerous years, & with NHK TV & Radio programs
- Additional training & professional staff will serve as co-facilitators for components of the instructional & recreational program as needed.
Get in Touch


text:
Employment Offices by County
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Handy Andy Industrial Temporary Help Services
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The following employment offices are located in Alcoa, Tennessee. Please select an employment agency in Alcoa to view the details of the employment services they provide.
Manpower - Temporary Help
269 Cusick Road Suite E
Alcoa, TN 37701
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text:
Owning Up
Empowering Adolescents to Confront Social Cruelty, Bullying, and Injustice
- Rosalind Wiseman - RPW Inc. (author & consultant)
A Joint Publication of the Association for Middle Level Education, Foreword by Richard Weissbourd
Bullying Prevention | Health & Wellness | Schoolwide Discipline & Bully Prevention
Empower students to stand up for what matters
Social dynamics, conflicts, and bullying influence every child's ability to learn. At the same time, a safe school climate depends on teaching students the skills to manage their emotions and critically think through solutions to social conflicts. How, then, do you prepare youth to be engaged learners and responsible, socially conscious citizens? Owning Up offers a solution by teaching young people to understand their individual development in relation to group behavior, the influence of social media on their conflicts, and the dynamics that lead to discrimination and bigotry. Whether you're teaching in a school, a team, or a youth-serving organization, Owning Up is a flexible, dynamic curriculum that respects your knowledge of the young people you work with and the communities in which you serve.
While there is no one-size-fits-all curriculum, Owning Up takes us leaps forward by
- Designing sessions to be easily facilitated by a school counselor, teacher, leader, or other professional in small group settings
- Combining discussions, games, and role-playing to engage adolescents in the complexities of social culture
- Exploring and connecting critical topics such as media analysis, gender, sexual harassment, racism, gossip, and self-image
Created in collaboration with children and teens, Owning Up helps young people identify and be critical of social issues in their lives--from bullying and harassment in the classroom to systems of power and oppression in the world around them.
HEOA Compliance
Available formats
|Electronic Version
|Suggested Retail Price: $36.95
|Bookstore Price: $29.56
|Suggested Retail Price: $36.95
|Bookstore Price: $29.56
Should you need additional information or have questions regarding the HEOA information provided for this title, including what is new to this edition, please email email@example.com. Please include your name, contact information, and the name of the title for which you would like more information. For information on the HEOA, please go to http://ed.gov/policy/highered/leg/hea08/index.html.


text:
- 1 Bed
- 2 Baths
- Apartment/Condo
- 1,235 sq.ft.
[MLS®#: R2336663]Simply the best – the Developer's original display home. This rarely available and...Read More
Listing Provided By: Royal LePage Sussex
- 1 Bed
- 1 full, 1 half Baths
- Apartment/Condo
- 1,203 sq.ft.
[MLS®#: R2331804]Welcome to Shaughnessy Place--a highly coveted & secure concrete development on the ...Read More
Listing Provided By: eXp Realty
- 1 Bed
- 2 Baths
- Apartment/Condo
- 1,245 sq.ft.
[MLS®#: R2333671]Welcome to this completely renovated suite at the uber exclusive Shaughnessay Place!...Read More
Listing Provided By: Nu Stream Realty Inc.
REBGV The data relating to real estate on this web site comes in part from the MLS Reciprocity program of the Real Estate Board of Greater Vancouver. Real estate listings held by participating real estate firms are marked with the MLSR logo and detailed information about the listing includes the name of the listing agent. This representation is based in whole or part on data generated by the Real Estate Board of Greater Vancouver which assumes no responsibility for its accuracy. The materials contained on this page may not be reproduced without the express written consent of the Real Estate Board of Greater Vancouver. Copyright 2018 by the Real Estate Board of Greater Vancouver, Fraser Valley Real Estate Board, Chilliwack and District Real Estate Board, BC Northern Real Estate Board, and Kootenay Real Estate Board. All Rights Reserved.


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What was once considered psychological healthy (or at least not unhealthy) is now considered to be mental illness. Some of the behaviors, thoughts, and feelings that were within the then-normal range of human experience are now deemed to be in the pathological part of the continuum. Thus, the actual definition of mental illness has broadened, creating a bigger tent with more people under it. This explanation implies that we, as a culture, are more willing to see mental illness in ourselves and in others.
The increasing prevalence is in part because each edition of the DSM has increased the overall number of disorders. The DSM-I, from 1952, listed 106; the DSM-III, from 1980, listed 265, and the current DSM-IV has 297. (Complaints about this ever-increasing total led the chair of the DSM-5 task force, David Kupfer, to announce that the total number of disorders in DSM-5 will not increase. One way to add new diagnoses—and DSM-5 will—but not increase the total is to make a disorder in a previous edition into a "subtype" of another disorder in the new edition, thereby keeping two diagnostic entities, but with one subsumed under another.)
The increasing number of disorders comes about because some "problems" that were not previously considered to be mental illness were reclassified as such by their inclusion in the DSM—and it is the DSM that functionally defines mental illness in the United States.
As an example, prior to the DSM-IV, there was no diagnosis of Asperger's syndrome; rather, people with what is now called Asperger's would have been diagnosed with autism ("high functioning" autism) or not diagnosed at all. This syndrome was added as a separate disorder to highlight the different forms that autism symptoms may take and to focus research on the most effective treatments for Asperger's. Others, however, claimed that the diagnostic label pathologized quirkiness. (In DSM-5, Asperger's is classified as a subtype of a newly consolidated single diagnosis "autism spectrum disorder.")
Some of the disorders added to DSM editions are primarily—or wholly—medical in nature. One example is the diagnosis of "breathing-related sleep disorder," which arises from medical problems that interfere with sleep. One such medical problem is obstructive sleep apnea, which occurs when the muscles of the throat relax so much during sleep that they narrow or block the airway. Throughout the night, people with obstructive sleep apnea have their deep sleep cut short as they relax because they stop breathing; once in a lighter phase of sleep, they breathe normally again. This disorder is not a mental disorder, but a medical one.
Another example is the "disorder" "caffeine intoxication," characterized by at least five symptoms after consuming the equivalent of two to three cups of coffee: restlessness, gastrointestinal problems, difficulty sleeping, nervousness, and rapid heartbeat. To meet the diagnosis, the symptoms must impair functioning in some way. It's hard to believe that an episode of too much coffee or Red Bull constitutes a mental disorder, but there you have it. DSM-5 has added "caffeine withdrawal" as a diagnosis—characterized by a withdrawal headache plus at least one other symptom, such as drowsiness, that interferes with some aspect of functioning. With disorders like this in the DSM, it's no wonder that half of Americans will have a diagnosable disorder in their lifetimes. The wonder is why more Americans won't!
Why will half the U.S. population have a mental illness?


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Playtime does not have to be over just because childhood has ended. As a transgender man and a recovering addict and alcoholic, my playtime has only just begun! I am well aware that l can be ridiculous at times. I get easily excited when visiting new places and seeing new things. The slightest thing, a newborn lamb, a soaring seagull, a beautiful flower, any of these can cause me to bounce around with excitement like Tigger.
People often comment on my childlike nature and boundless energy. I think I'm a bit like Marmite, to be honest. My bouncy energy is either cute and endearing or unbecoming and annoying! It's not my fault, I am brand new, reborn and very excited to be here. Here are five reasons why!
1. I have only been awake since 2010
There was no playtime before 2010; I was a miserable, drunk and stoned mess. I was sleepwalking through my life, numbing myself in a desperate attempt to escape myself.
Not only was I asleep in being anaesthetized with alcohol and weed, but I was also asleep within my soul. I was self-absorbed, I wallowed in self-pity and blamed everything outside myself for the pain I felt.
When I walked into the rooms of Alcoholics Anonymous (by some miracle I still cannot fully explain) and became clean and sober, my entire perspective changed. I had a dramatic paradigm shift in how I saw the world and my place in it and how I responded to life. With this awakening came a profound gratitude and a desire to make the most of every day.
2. I didn't start (The correct) puberty until 2011
With a clear head, I was able to get to the bottom of my mental health issues. Surprisingly, (at the time at least, though now I can see it has always been glaringly obvious!) gender dysphoria turned out to be the primary cause of my emotional distress. Despite being assigned female at birth, I was, in fact, a transgender male. With the support of my recovery program, I was able to find the courage and the support to come out and begin gender transition.
The experience of watching my body change with hormones and surgery is one I cannot adequately describe in words. I am in constant delight at my newly revealed body. The ever-changing reflection in the mirror never ceases to make me grin.
3. I am experiencing the world anew
The combination of my awakening and the birth of my true self, means I am experiencing many things for the first time.
The world is no longer viewed through a hazy filter now I am clean and sober. I see things in crisp bright technicolour. I often stare in awe at an autumn leaf dancing its way across the sky or at an entire field of grass blowing in the wind like fresh green waves, because it is so arresting to my newly awakened senses.
4. My body feels like home for the first time
I started drinking at the age of thirteen, which meant I didn't learn how to understand or manage my emotions, I drowned them. Now sober, I am also feeling things for the first time. The depth of feeling I have now is exquisitely varied and intense.
Not only am I feeling emotions, but I am also feeling my entire body. Before I transitioned, my body had been a source of pain, and I dealt with this by detaching from it. Now sober, I am present in my body for the first time in my life.
The body is the centre of everything we experience. Therefore, when you are not present, you miss so much. Now I am embodied, I can feel both my internal emotions and the external world interacting with my body. The way my partner's voice moves through my chest, making my heart swell with joy or the way music penetrates every pore of my being and animates my body. I had no idea I had been missing out on so much.
5. I am allowing myself the playtime I missed out on
It is thrilling to be awake and to be my true self. I'm learning things and doing things at the age of forty-four that most people do in their childhood. I can look at this in two ways. The first is to see these as wasted years and be sad and angry. Had I realised I am trans earlier in life, I would have had the chance to be a young man rather than a middle-aged one.
The second way to look at this is to focus on making the most of the years I still have left to live. That's not to say I deny myself the grief, acknowledging it is crucial. However, being bitter and angry will only waste more precious time. Instead, I deal with the grief by transforming its energy from sadness into a determination to suck the marrow out of life.
This is why I come across an overgrown child and also why I make no apologies for being so! I have a second chance at life. I might be forty-four and my childhood a distant memory, but I can actively choose for my playtime to be right here and right now.
What about yourselves? Have you overcome a difficult time and are making up for it now? Are you just a big kid at heart and proud? What are the ways you make sure you keep playtime in your life? Let me know in the comments below!
Finlay Games is the founder of The Recovery Writer and the host of Finntheinfinncible. He is a freelance writer and speaker for hire, who advocates, informs and inspires on topics of mental health, recovery, gender transition, and sexuality.


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SAN FRANCISCO (MarketWatch) -- Technology stocks battled their way back into positive territory Friday afternoon to close higher as the broader market declined after the government reported another sharp contraction in U.S. payrolls.
The Dow Jones Industrial Average DJIA, +1.74% lost 16.6 points after the Labor Department reported that employers cut back their hiring in March. Read more.
The Nasdaq Composite Index COMP, +0.61% gained more about 8 points, or less than 1%, to close at 2,371 points. The Morgan Stanley High Tech 35 Index MSH, +0.57% added less than 1%, while the Philadelphia Semiconductor Index SOX, +0.53% fell less than 1%.
Google Inc. GOOG, -0.72% added 3.5%, eBay Inc. EBAY, +0.72% was ahead nearly 4% and Apple Inc. AAPL, -0.22% rose about 1% Microsoft Corp. MSFT, +1.23% was up less than 1%.
However, other major technology giants were in the red, including Oracle Corp. ORCL, +0.47% IBM Corp. IBM, +1.14% and Hewlett-Packard HPQ, +0.22%
Among Internet giants, Amazon.com AMZN, -0.91% was up 2.6% and Yahoo Inc. YHOO gained less than 1%.
In the chip sector, Intel Corp. INTC, +1.67% and rival Advanced Micro Devices Inc. AMD, +2.38% declined less than 1%.
Chip equipment maker Applied Materials Inc. AMAT, -3.95% and networking gear giant Cisco Systems Inc. CSCO, +2.13% advanced a fraction.


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Subaru Forester Limited
Experience driving perfection in the 2019 Subaru Forester. Smooth gearshifts are achieved thanks to the 2.5 liter 4 cylinder engine, providing a spirited, yet composed ride and drive. All wheel drive provides for safe passage, regardless of road or weather conditions. Top features include heated front seats, an automatic dimming rear-view mirror, a blind spot monitoring system, automatic dimming door mirrors, front bucket seats, a power liftgate, rear wipers, and cruise control. Features such as automatic climate control and leather upholstery prove that economical transportation does not need to be sparsely equipped. For drivers who enjoy the natural environment, a power moon roof allows an infusion of fresh air. Audio features include a CD player with MP3 capability, steering wheel mounted audio controls, and 9 speakers, providing excellent sound throughout the cabin. Subaru also prioritized safety and security with features such as: dual front impact airbags, front side impact airbags, traction control, brake assist, a panic alarm, an emergency communication system, and 4 wheel disc brakes with ABS. Electronic stability control ensures solid grip atop the road surface, no matter how challenging the driving conditions. We have the vehicle you've been searching for at a price you can afford. Please don't hesitate to give us a call.


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Seattle Children's Museum has been a hub for early learning in our community for 40 YEARS now, but we're just getting started! In 2018 alone, we created 45+ new educational programs, built or upgraded 8 hands-on exhibits, and expanded access for underserved families through the Seattle Public Library Museum Pass and IMLS Museums For All initiatives.
We have big plans for 2019, but we can only achieve them with your help!
Join us on Thursday, March 21st for our annual Birthday Celebration! Explore the museum while enjoying Guest Performers, Live and Silent Auctions, Education Demos, a Wine Ring Toss, Catering, Libations, and more at this annual fundraiser.
Proceeds from the Birthday Celebration benefit museum programming, exhibits, and our Passport 2 Play program, which ensures early childhood education opportunities for kids regardless of their economic circumstances. #LevelThePlayingField
Thank you to last year's donors!
ACT Theater
AEG Live
Kenny and Marleen Alhadeff
Allied Seattle
Arena Sports Issaquah
Arena Sports SODO
Argosy Cruises
Arthur Murray Dance School
Bloedel Reserve
Caffe Ladro
Caffe Vita
Central Cinema
Chateau Ste Michelle
Chihuly Garden & Glass
Cloutier Ortega PLLC
Coast Gateway Hotel
Collections Café
Columbia Tower Sky View Observatory
Dilletante Chocolates
DRY Soda Co.
Easy Street Records
Elliott Bay Book Company
Emerald City Comic Con (ECCC)
Epic Team Adventures
Everyday Music
Fairmont Olympic Hotel
Flatstick Pub
Frye Art Museum
Heavy Restaurant Group
Hyatt Place
La Marzocco
Light In The Attic Records
LunchBox Laboratory
Macrina Bakery
Matthew Steele Salon & Spa
Mercer Street Books
Mox Boarding House
Museum of Flight
Museum of History and Industry (MOHAI)
Museum of Pop Culture (MoPOP)
Neighborhood Grills
Nordic Museum
Northwest African American Museum (NAAM)
Northwest Film Forum
Northwest Outdoor Center
Northwest Trek Wildlife Park
Pac-12 Sports
Pacific Science Center
Pagliacci Pizza
PBY – Naval Air Museum
Peddler Brewing Company
Pottery Northwest
Puzzle Break
Queen Anne Book Company
Ride the Ducks
SANCA (School of Acrobatics and New Circus Arts)
Schwartz Brothers Restaurants
Seattle Aquarium
Seattle Art Museum
Seattle Bouldering Project
Seattle Children's Theatre
Seattle Mariners Baseball
Seattle Monorail
Seattle Reign
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Seattle Shakespeare Company
Seattle Sounders FC
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STG Presents
Storyville Coffee
Tennis Center Sand Point
The Cycle Saloon
The Reptile Zoo
The Wing Luke Museum of the Asian Pacific American Experience
Theo Chocolate
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text: Up to Oxfordshire for day 5 of the tour. Taking in Stockham Primary School in Wantage and Bayards Hill in Headington. Share this postShare with FacebookShare with TwitterShare with WhatsAppPost navigationPreviousPrevious post:Day 3 of the VIAM School TourNextNext post:Day 4 of the VIAM Schools TourRelated postsHalf Term Musical Theatre CampFebruary 7, 2019New Hope Club will be appearing at VIAM2019January 26, 2019


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The Already but Not Yet of the Kingdom of God
"The already but not yet of the Kingdom of God" Dr. Jerry Nelson www.soundliving.org
In the OT God is presented as the supreme King of the universe, ruling over all. But from the moment of Adam's sin, it became apparent that something broke – mankind now largely rebelled against the King's rule. And the result was that not only was humanity broken from that day forward but all creation was affected. Human beings (Romans 5:12) and the world in which we live (Romans 8:20) have been altered by sin so that we barely reflect the glory of God or the glory with which we were first created.
The Bible starts, in Genesis, with the tree of life (Genesis 2:9) in a setting of intimacy between God and mankind (Genesis 2:15-25).
The Bible ends, in Revelation, with the tree of life (Revelation 22:2) in a setting of restored intimacy between God and mankind (Revelation 21:3).
Between Genesis and Revelation, the message of the Bible is the story of humanity's on-going rebellion and God's more powerful grace to restore humanity, the earth and his universe.
- Starting in Genesis 3:15, God promised a reversal of the effects of sin.
- In Genesis 12 Abraham was promised that through his offspring the whole world would be blessed by God.
- The Prophets saw how broken the world was and looked forward to the day when sin's domination would be ended and God's righteous and benevolent rule would again reign supreme.
The Prophets likewise wrote that this life-changing and world-changing rule of God would be ushered in by his appointed Messiah.
Then with the NT we see Jesus presenting himself as that "Messiah." He came proclaiming the good news of the Kingdom of God – the rule of God overcoming the forces of evil which have held sway over humanity and the rest of creation for millennia. He came teaching us to pray "Thy kingdom come, Thy will be done on earth as it is in heaven."
Satan's reign (and our cooperation with it) in the world is characterized by sexual immorality, impurity and debauchery; idolatry and witchcraft; hatred, discord, jealousy, fits of rage, selfish ambition, dissensions, factions and envy; drunkenness, orgies, and the like, and it ends in death!
God's reign in the world is characterized by love, joy, peace, patience, kindness, goodness, faithfulness, gentleness and self-control and it is life!
Jesus came ushering in God's (His) kingdom rule but not all at once. He announced both what would be true in the future AND how some of that future would be experienced now. We can rightly describe it as the future invading the present. Paul wrote that our citizenship is in heaven (Philippians 3:20). We, who are saved by God's grace through faith in Jesus, are future "kingdom of God" people living in the present kingdom of this world. We are colonists not from some other place in the past but from the future. We are tethered to the future but living in the present.
This work of Jesus produces two great truths:
- We have an almost unimaginable future (1 Corinthians 2:9) that has been and is secured by God's grace:
Revelation 21:1-4
"Then I saw a new heaven and a new earth, for the first heaven and the first earth had passed away, and there was no longer any sea. 2 I saw the Holy City, the new Jerusalem, coming down out of heaven from God, prepared as a bride beautifully dressed for her husband. 3 And I heard a loud voice from the throne saying, "Now the dwelling of God is with men, and he will live with them. They will be his people, and God himself will be with them and be their God. 4 He will wipe every tear from their eyes. There will be no more death or mourning or crying or pain, for the old order of things has passed away…"
What we often refer to as "heaven" is actually the new earth that God will recreate (2 Peter 3:7,13). And on that new earth we know, from God's promises, it will be a radically different experience for us than now. There will be peace with God – no fear of alienation. There will be the peace of God – our relationships will be whole and healthy. The fruit of the Spirit will not be sporadic in us but consistent. The heartaches we know now will be impossible then. Even the physical earth will be restored to greater glory (Romans 8). And our bodies will be resurrected, immortal and incorruptible.
- The second thing that is true is that some of that future blessing of the kingdom of God, God's complete and uncontested rule, is experienced even now.
If someone gave you a $1000 down payment on a parcel of land, the earnest money and what it could provide you are yours now even though you don't yet have the full amount that will be paid in the future. The Holy Spirit of God is called God's down payment (Ephesians 1:13-14) on what will be ours in the future but that Holy Spirit and what he will provide are also ours now!
When the Kingdom of God is completely fulfilled on the new earth, there will be a peace with God untroubled by circumstances and doubt, but even now we can know a great measure of that peace. Or to say it differently, that future complete peace even now invades the present in part.
When the Kingdom of God is completely fulfilled on the new earth peace with each other will be perfect but even now we can know a measure of that peace through forgiveness, reconciliation, kindness, and genuine fellowship. The future complete peace with each other even now invades the present in part.
When the Kingdom of God is completely fulfilled on the new earth we will live in resurrected, immortal, and incorruptible bodies. When Jesus was on earth healing people he was giving them (and us) a glimpse into the future. He was demonstrating the power of the Kingdom of God that will eventually overcome all the devastating effects of sin – including disease, debilitation and death. But even now, when God heals people today he is giving us a taste of what is to come. That healing may be by the immediate intervention of God, what we call a miracle, or by the mediated intervention of God through medicine. But in either form it is the future wholeness of the Kingdom of God, now in part, invading the present.
What we are experiencing now, by God's grace, is what some call the "already but not yet" of the Kingdom of God. The Kingdom of God has been established in Jesus' death and resurrection; it is a certainty and we are already experiencing some of the effects of it. But we are not yet experiencing its fullness which is yet to come. The Kingdom of God is "already, but not yet." We have the privilege of living in expectation of what God can and often does even now but accepting that the fullness is yet to come.
"Maranatha" ("Our Lord Comes" or "Come, Lord Jesus!")


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Nordea Analys
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10. joulu 2018∣
Nordea Markets
Awareness of global food system's significance in the climate battle is on the rise, positively shifting demand to more sustainable protein sources.
16. loka 2018∣
Martin O'rourke
Inequality has grown across the OECD in the past 30 years and The Nordics have hardly been immune. We look at the cost of the income and wealth gap.
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Martin O'rourke
It's good to be at the front of the conversation. And when it comes to ESG, it seems we most definitely are.
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Nordea Markets
Our Chief analyst Andreas Wallström shares his perspective on how climate is affecting companies, sectors and society at large.
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Nordea Markets
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Johan Trocmé
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If you're looking for an old home to buy and fix up, one thing you'll want to inspect before closing the deal is the foundation. Foundation damage can be costly to repair, so you want to factor the additional expense into the price of the house ahead of time or work out a deal for the owner to repair the foundation. Here are some signs that indicate the need for foundation repairs and what kind of work the home may need.
6 February 2019
If you are worried about problems with your roof, improvements when doing repairs are essential to prevent leaks. Making improvements to your roof and stopping leaks will also prevent the serious issues with rot, mold, and structural damage to your home. Here are some tips to help with repairs and improvements that will help prevent roof problems from turning into serious damage to your home: 1. Inspecting and Cleaning Roof Regularly to Reduce Wear
15 January 2019
Small problems around your home never seem like a big deal at the time, but they have the potential to lead to major issues if ignored. This is especially true when it comes to your roof, which needs to be in good shape to keep water out of your home. Here are some potential consequences of ignoring minor roof issues. Caved In Ceilings Your problems are not going to suddenly cause your entire ceiling to cave in, but it will start off small.
15 December 2018
If your commercial building with a modified bitumen flat roof is leaking water into your office or warehouse space, then it is important to figure out exactly where it is leaking. Not only do you need to find the leak to stop the annoying drips and put your buckets away, but also because leaking roofing materials are very dangerous for the underlying structure of the building. Finding a leak on modified bitumen flat roof isn't always as simple as just climbing up and looking for wet spots.
9 November 2018
The roofing materials that you choose to have installed on your home can be durable and energy-efficient. There are many different types of choices of roofing materials that you can have to make your home more energy-efficient, as well as different maintenance and repair needs that come with each type of material. Here are some roofing maintenance tips to help with installation of new energy-efficient roofing materials. 1. Better Roofing Durability With Routine Cleaning and Fall Maintenance
17 October 2018
If you have decided to use solar power to generate electricity for even part of your home, you will be saving money and the environment. You may have contacted a solar company to discuss how much power you need to generate, how many panels you will need, and what type of storage batteries to use for times when there is not enough sunlight. While this is a good start, before you go any further you are going to need to talk with a roofing contractor.
1 October 2018
If you find numerous squirrels, rats, or even birds living in your attic, you may check your gutters and siding for holes. But your roof vent may actually be the reason so many critters are living in your attic. The shingles around the base of your roof vent may be damaged. Here's how pests use your roof vent to enter your home and how you can repair the vent now.
15 September 2018
Is it time for a new roof and you're thinking about a change of style? Fortunately, when it comes to asphalt shingles, you have many choices when it comes to the color. When choosing a color for your roof, there are a few things you should keep in mind. Asphalt shingles can last for decades, so you want to make sure you choose a color wisely. The following information can ensure you make a choice that you can live with and appreciate for many years to come.
30 August 2018
A roof is an investment, since it is the main barrier between your home and weather damage. Taking care of your roof can help extend its life while also protecting your home's interior. The following are a few tasks you should do that will help prevent damage to your roofing. Keep your gutters clean Gutters may seem like a minor thing that would have little impact on a roof, but the opposite is true.
30 July 2018
Tin roofs were common on colonial-era homes, and quite a few homes built in this time period still retain their original roof. Unfortunately, lack of maintenance has caused severe rust damage to many of these beautiful roofs. If you or a family member own a home with an old tin roof, it's worth restoring it instead of replacing it. You'll preserve the historical appeal of your home while protecting the interior of the home from leaks.
11 July 2018


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February 15, 2019
Written By Justus Mwangi
Day 1: After breakfast depart on a pleasant drive to the floor of the Great Rift Valley with its spectacular views of the valley below. Continue to Lake Nakuru National Park, famous as home to thousands of lesser and greater flamingo. This park also provides sanctuary for Rothschild giraffe, black and white rhino and the Read More…
January 16, 2019
Written By Wilson William
This Camping trip take you to the best national Parks staying on the campsite. It will take you into a very close contact with nature. The well selected Campsite are well equipped with well maintained washroom facillities, water and electricity are available. Day 1 : Lake Manyara. Depart from Arusha to Lake Manyara national park to Read More…
December 7, 2018
Written By TogetherSahara
Day 1 : Marrakech – Ait Ben Haddou – Ouarzazate – Rose Valley -Dadés Gorges We start from Marrakech before 8:00, in order to drive to Ouarzazate, a former caravan town on the silk and salt route in the eastern foothills of the Atlas Mountains. Ouarzazate is known as the Gateway to the Sahara passing through Read More…
December 6, 2018
Written By AfricaNaturePhoto
The northern Serengeti is home to a huge number of resident animals including Lion, Leopard, Cheetah, Elephant, Buffalo, Eland, Black Rhinos and Occasionally wild dogs are even being seen. This is also a wonderful time of year to witness one of three significant events that happens during the Great Migrations – The annual river crossings.
November 15, 2018
Written By Modest Tours & Travels
Our Classic Kenya packages offer you an authentic East African style safari while staying in excellent hotels, lodges and permanent camps.
November 15, 2018
Written By Modest Tours & Travels
Go in search of Kenya's abundant wildlife in the classical African game parks of world-famous Masai Mara, Samburu National Park, Lake Nakuru, Amboseli and Tsavo West.
October 27, 2018
Written By Phillip Zulu
Livingstone Day Trip gives clients a total involvement intothe most activities of the day. Their day will start with the tour of Victoria Falls in the morning for 3 hour. After the tour of the Falls ,clients will then proceed to have lunch in readiness for combined game drive and walking safari in the afternoon.
October 27, 2018
Written By Phillip Zulu
This activity is done in Mosi-oa-Tunya National Park in Livingstone Zambia.The client will start will a 3 hour game drive into the belly of the park.After the game drive clients will then proceed to do 1 hour walking safari to see the White Rhinos.
October 19, 2018
Written By Brian Temu
We will gladly tailor-make your individual travel arrangements as per your wishes and ideas. Tanzania has been blessed with the most beautiful landscapes and the country offers a wide range of different activities and things to see. Combine the icy peak of Mount Kilimanjaro with pure relaxation at the Indian Ocean or enjoy an exciting Read More…
October 19, 2018
Written By Alex Simon
4 Day Kruger Park and Sabi Sands Safari Transport provided Three meals a day Accommodation Safari drives in the Sabi Sands and Kruger National Park A warm brand of African hospitality welcomes you as you embark on a 4 day safari to the Kruger National Park and Sabi Sands Game Reserve, where exploring the vast plains Read More…
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Energy Exchangers (EE's) are an integral part of our studio family – their passion and dedication is what makes our community so special. In exchange for working one 5 hour shift per week of cleaning the studio, EE's will receive unlimited yoga and lots of other perks!
Want to become a bigger part of our community in exchange for free yoga? Have 5 hours a week to spare? Our Energy Exchange program is for you!


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What Are Deadpool's Powers? They're Actually All Thanks to Another Mutant
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| Celia Fernandez
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Thanks to his sarcasm, his habit of breaking the fourth wall, and his deeply inappropriate one-liners, Deadpool has easily established himself as one of Hollywood's most exciting new superheroes. The character actually made its debut back in 1997, but 11 years later, Ryan Reynolds brought the antihero to life on the big screen in 2016's Deadpool and its highly-anticipated sequel, Deadpool 2.
While you might know a few things about his obsession with unicorns and his deep love for Vanessa, there are still a few tidbits about Deadpool you might want to brush up on. For those who aren't avid followers of the comics or whoever just needs a refresher ahead of the sequel's May 18 debut, we're diving deep into the back story of how Deadpool actually came to be.
How Does He Get His Powers?
Wade - Wilson - Forces - Assassin - Cancer
Wade Wilson is a dishonorably discharged special forces operative who ends up working as a mercenary and assassin, and later he receives a terminal cancer diagnosis that sparks his journey into becoming Deadpool. Wilson is approached to take part in an experiment that is supposedly going to cure his cancer with a mysterious serum, which is made from Wolverine's genes and aims to awaken...
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text: Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List HSP90B1 recombinant protein :: Endoplasmin (HSP90B1) Recombinant Protein Catalog # MBS1265357 Unit / Price 0.01 mg / $160 +1 FREE 8GB USB 0.05 mg / $200 +1 FREE 8GB USB 0.1 mg / $295 +1 FREE 8GB USB 0.2 mg / $480 +1 FREE 8GB USB 0.5 mg / $790 +1 FREE 8GB USB 1 mg / $1,215 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Endoplasmin (HSP90B1), Recombinant Protein Popular Item Full Product Name Recombinant Human Endoplasmin (HSP90B1), partial Product Synonym Names 94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog Product Gene Name HSP90B1 recombinant protein[Similar Products] Product Synonym Gene Name GRP94; TRA1[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP MBS1265357 COA COA PDF Sequence Positions 27-799. Partial Sequence VDGTVEEDLG KSREGSRTDD EVVQREEEAI QLDGLNASQI RELREKSEKF AFQAEVNRMM KLIINSLYKN KEIFLRELIS NASDALDKIR LISLTDENAL SGNEELTVKI KCDKEKNLLH VTDTGVGMTR EELVKNLGTI AKSGTSEFLN KMTEAQEDGQ STSELIGQFG VGFYSAFLVA DKVIVTSKHN NDTQHIWESD SNEFSVIADP RGNTLGRGTT ITLVLKEEAS DYLELDTIKN LVKKYSQFIN FPIYVWSSKT ETVEEPMEEE EAAKEEKEES DDEAAVEEEE EEKKPKTKKV EKTVWDWELM NDIKPIWQRP SKEVEEDEYK AFYKSFSKES DDPMAYIHFT AEGEVTFKSI LFVPTSAPRG LFDEYGSKKS DYIKLYVRRV FITDDFHDMM PKYLNFVKGV VDSDDLPLNV SRETLQQHKL LKVIRKKLVR KTLDMIKKIA DDKYNDTFWK EFGTNIKLGV IEDHSNRTRL AKLLRFQSSH HPTDITSLDQ YVERMKEKQD KIYFMAGSSR KEAESSPFVE RLLKKGYEVI YLTEPVDEYC IQALPEFDGK RFQNVAKEGV KFDESEKTKE SREAVEKEFE PLLNWMKDKA LKDKIEKAVV SQRLTESPCA LVASQYGWSG NMERIMKAQA YQTGKDISTN YYASQKKTFE INPRHPLIRD MLRRIKEDED DKTVLDLAVV LFETATLRSG YLLPDTKAYG DRIERMLRLS LNIDPDAKVE EEPEEEPEET AEDTTEDTEQ DEDEEMDVGT DEEEETAKES TAE OMIM 191175 3D Structure ModBase 3D Structure for P14625 Host E Coli Purity/Purification Greater than 90% as determined by SDS-PAGE. (lot specific) Form/Format Liquid containing glycerol Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Preparation and Storage Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. ISO Certification Manufactured in an ISO 9001:2008 Certified Laboratory. Other Notes Small volumes of HSP90B1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for HSP90B1 recombinant protein Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. 1 Publication Product Categories/Family for HSP90B1 recombinant protein Metabolism SDS-Page of HSP90B1 recombinant protein (Note: Representative image, actual molecular weight may vary depending on Tag type and expression host) TOP NCBI/Uniprot data below describe general gene information for HSP90B1. It may not necessarily be applicable to this product. NCBI GI # 4507677 NCBI GeneID 7184 NCBI Accession # NP_003290.1 [Other Products] NCBI GenBank Nucleotide # NM_003299.2 [Other Products] UniProt Primary Accession # P14625 [Other Products] UniProt Secondary Accession # Q96A97[Other Products] UniProt Related Accession # P14625[Other Products] Molecular Weight 93.2kD TOP NCBI Official Full Name endoplasmin NCBI Official Synonym Full Names heat shock protein 90kDa beta family member 1 NCBI Official Symbol HSP90B1 [Similar Products] NCBI Official Synonym Symbols ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m [Similar Products] NCBI Protein Information endoplasmin UniProt Protein Name Endoplasmin UniProt Synonym Protein Names 94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog Protein Family Endoplasmin UniProt Gene Name HSP90B1 [Similar Products] UniProt Synonym Gene Names GRP94; TRA1; GRP-94 [Similar Products] UniProt Entry Name ENPL_HUMAN TOP Product References and Citations for HSP90B1 recombinant protein Human homologue of murine tumor rejection antigen gp96 5'-regulatory and coding regions and relationship to stress-induced proteins.Maki R.G., Old L.J., Srivastava P.K.Proc. Natl. Acad. Sci. U.S.A. 87:5658-5662(1990) Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors.Chang S.C., Erwin A.E., Lee A.S.Mol. Cell. Biol. 9:2153-2162(1989) The association of heat shock protein gp96 with HBV-derived peptides in vitro.Meng S., Tien P. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.Nat. Biotechnol. 21:566-569(2003) A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.Meunier L., Usherwood Y.-K., Chung K.T., Hendershot L.M.Mol. Biol. Cell 13:4456-4469(2002) Proteomic analysis of early melanosomes identification of novel melanosomal proteins.Basrur V., Yang F., Kushimoto T., Higashimoto Y., Yasumoto K., Valencia J., Muller J., Vieira W.D., Watabe H., Shabanowitz J., Hearing V.J., Hunt D.F., Appella E.J. Proteome Res. 2:69-79(2003) Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.Zhang H., Li X.-J., Martin D.B., Aebersold R.Nat. Biotechnol. 21:660-666(2003) A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone.Liu B., Yang Y., Qiu Z., Staron M., Hong F., Li Y., Wu S., Li Y., Hao B., Bona R., Han D., Li Z.Nat. Commun. 1:79-79(2010) ErratumLiu B., Yang Y., Qiu Z., Staron M., Hong F., Li Y., Wu S., Li Y., Hao B., Bona R., Han D., Li Z.Nat. Commun. 3:653-653(2012) Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.Chi A., Valencia J.C., Hu Z.-Z., Watabe H., Yamaguchi H., Mangini N.J., Huang H., Canfield V.A., Cheng K.C., Yang F., Abe R., Yamagishi S., Shabanowitz J., Hearing V.J., Wu C., Appella E., Hunt D.F.J. Proteome Res. 5:3135-3144(2006) Elucidation of N-glycosylation sites on human platelet proteins a glycoproteomic approach.Lewandrowski U., Moebius J., Walter U., Sickmann A.Mol. Cell. Proteomics 5:226-233(2006) OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.Christianson J.C., Shaler T.A., Tyler R.E., Kopito R.R.Nat. Cell Biol. 10:272-282(2008) Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.J. Proteome Res. 8:651-661(2009) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.Sci. Signal. 3:RA3-RA3(2010) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.Sci. Signal. 4:RS3-RS3(2011) A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.Cloutier P., Lavallee-Adam M., Faubert D., Blanchette M., Coulombe B.PLoS Genet. 9:E1003210-E1003210(2013) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014) TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated withHSP90B1 recombinant protein Reference Product PubMed Publications HSPA5 recombinant protein >8 publications with HSP90B1 and HSPA5 PDIA6 recombinant protein >2 publications with HSP90B1 and PDIA6 P4HB recombinant protein >2 publications with HSP90B1 and P4HB CALR recombinant protein >2 publications with HSP90B1 and CALR Pathways associated with HSP90B1 recombinant protein Products by Pathway Pathway Diagram ATF6-alpha Activates Chaperone Genes Pathway antibodies ATF6-alpha Activates Chaperone Genes Pathway Diagram ATF6-alpha Activates Chaperones Pathway antibodies ATF6-alpha Activates Chaperones Pathway Diagram Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram Estrogen Signaling Pathway antibodies Estrogen Signaling Pathway Diagram Estrogen Signaling Pathway antibodies Estrogen Signaling Pathway Diagram IL6-mediated Signaling Events Pathway antibodies IL6-mediated Signaling Events Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Innate Immune System Pathway antibodies Innate Immune System Pathway Diagram Metabolism Of Proteins Pathway antibodies Metabolism Of Proteins Pathway Diagram NOD-like Receptor Signaling Pathway antibodies NOD-like Receptor Signaling Pathway Diagram Diseases associated with HSP90B1 recombinant protein Disease Name Pubmed Publications Inflammation Antibodies >5 publications with HSP90B1 and Inflammation Liver Diseases Antibodies >4 publications with HSP90B1 and Liver Diseases Carcinoma, Hepatocellular Antibodies >3 publications with HSP90B1 and Carcinoma, Hepatocellular Liver Neoplasms Antibodies >3 publications with HSP90B1 and Liver Neoplasms Lung Diseases Antibodies >3 publications with HSP90B1 and Lung Diseases Disease Models, Animal Antibodies >3 publications with HSP90B1 and Disease Models, Animal Testicular Diseases Antibodies >2 publications with HSP90B1 and Testicular Diseases Neoplasms, Experimental Antibodies >2 publications with HSP90B1 and Neoplasms, Experimental Breast Neoplasms Antibodies >2 publications with HSP90B1 and Breast Neoplasms Lung Neoplasms Antibodies >2 publications with HSP90B1 and Lung Neoplasms Organs/Tissues associated with HSP90B1 recombinant protein Organ/Tissue Name Pubmed Publications Blood Antibodies >8 publications with HSP90B1 and Blood Brain Antibodies >6 publications with HSP90B1 and Brain Bone Antibodies >5 publications with HSP90B1 and Bone Liver Antibodies >4 publications with HSP90B1 and Liver Bone Marrow Antibodies >4 publications with HSP90B1 and Bone Marrow Lung Antibodies >3 publications with HSP90B1 and Lung Testis Antibodies >3 publications with HSP90B1 and Testis Prostate Antibodies >2 publications with HSP90B1 and Prostate Lymph Node Antibodies >2 publications with HSP90B1 and Lymph Node Thyroid Antibodies >2 publications with HSP90B1 and Thyroid TOP © 2006-18 MyBioSource.com. 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