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As a father of a child with autism, Dr. Alysson Muotri knows how difficult and traumatic it can be for some to give a blood or tissue sample.
"I know the pain of having a kid going to the hospital," he said.
But as a researcher of neurological disorders at the University of California, San Diego, he also desperately needed patient-specific cells to study in his laboratory.
That's when he enlisted the help of the tooth fairy.
Muotri is one of a handful of researchers across the U.S. who is using discarded baby teeth to jump-start research into autism, Alzheimer's and other neurological disorders that have proven notoriously difficult to study. By soliciting baby teeth from affected patients, they can access patient-specific cells that can be manipulated and studied in the laboratory, and get a record of what individuals were exposed to dating back to before they were born.
"There's an interesting story behind every single tooth that arrives in the lab," he said.
Muotri hit on the idea of using baby teeth after learning about stem cell reprogramming developed by Shinya Yamanaka, who won a 2012 Nobel Prize for his work. Yamanaka invented a process to reprogram skin cells into stem cells that could then be coaxed to form any cell type in the body.
"Immediately, I thought, 'That's a great model for autism,'" Muotri said. "Because the problem with autism is we don't have brain cells to study."
Researchers had relied on mouse models or samples of brain tissue taken post-mortem. Neither was ideal. Only about 1 percent of treatments that work in mice also work in humans.
"They help us understand basic mechanisms, but when we go to find new drugs or new therapies, curing mice is not the same as curing humans," Muotri said.
He clearly couldn't take brain tissue from his patients, but now he had a way to grow the exact same brain tissue from their cells.
The easiest way to get those cells would be to take a blood sample or a tissue biopsy. But that would be difficult to get from children with autism.
"So I thought, 'Is there any tissue that people would discard?'" he said.
Scientists had tried using mouth swabs, hair cells, even urine as a source of cells, but none of those worked well. Baby teeth, on the other hand, fell out naturally, and if harvested quickly, could provide a viable source of cells for reprogramming.
Muotri's lab emailed 100 families affected by autism in the San Diego area. They created a Facebook page for what they dubbed the Tooth Fairy Project, and within a couple of years had registered 3,500 families and collected more than 300 teeth.
The project team sends interested parents a collection kit that includes a small tube with a special fluid inside, as well as a questionnaire about the child's diagnosis and symptoms. When their child loses a tooth, parents can pop it into the tube — after the tooth fairy has conducted her standard transaction — and send it to the lab.
The researchers extract cells from the dental pulp within the tooth and reprogram them to form stem cells. They can then trigger those stem cells to become neurons, growing enough to create a mini-brain in a petri dish. It's a long and expensive process taking up to a year to complete, but Muotri's lab is continually working to streamline the process.
Early nibbles of success
The project has already identified at least five gene mutations associated with autism, some of which had not been previously implicated.
Muotri described one case of an autistic boy from Brazil whose family sent in a baby tooth. The researchers could see that the neurons lacked the normal number of synapses. They sequenced the DNA from the tooth and found that the boy had a mutation not previously tied to autism. But researchers knew that the gene was important for creating synapses, the way brain cells communicate with each other. They also knew that a drug, hyperforin, helped promote the creation of synapses. They suggested the family try giving the boy St. John's Wort extract, which contains hyperforin.
Within a month, independent evaluations from the boy's school and psychologist confirmed an improvement in his social interactions.
"It's hard to conclude that this was caused by the St. John's Wort capsule, because this is just one patient," Muotri said. "But there are probably people under the autism spectrum that have mutations in their genes or metabolic pathways that we already know and there are drugs out there to help them."
Muotri recently used the technique to study a rare genetic disorder called Williams syndrome, that affects one in 10,000 people worldwide. The syndrome consists of a range of medical problems including developmental delays. But unlike autism that can result in impaired social functioning or communication, children with Williams syndrome are often overly friendly and have strong language skills.
When Muotri's team looked at Williams syndrome neurons under a microscope, they saw the brains have many more connections to other neurons than is typical. That might explain why children with Williams syndrome are super-social, gregarious in nature, while children with autism who have fewer neural connections struggle with social interaction, Muotri said.
Because stem cell reprogramming can be used to create any type of cell, baby teeth could provide the basis for researching many other conditions.
"I focus on brain tissue disorders, but I could make heart cells," Muotri said. "Instead of making a mini-brain, I could make a mini-heart to see if we have some drugs to treat the heart cells."
Other researchers are looking at new ways to use baby teeth for research. Dr. Lawrence Reiter, a neurology professor at the University of Tennessee, is using stem cells that already exist within dental pulp. Those cells can be transformed into neurons, bone, muscle and other tissue types, with none of the complex reprogramming needed with other types of cells.
"Unfortunately, the biggest challenge may be to convince other scientists that these stem cells can be made into neuronal cultures that accurately represent the human brain at the gene expression level," Reiter said.
His lab is now exploring some rare genetic conditions, including Prader-Willi syndrome, Angelman syndrome and others. One colleague is using brain cells derived from dental pulp to study the effects of the Zika virus.
Word of mouth
Collecting baby teeth may be a way to include many more individuals in research, Reiter said, particular when advocacy groups get the message out to their members that researchers need a supply of teeth.
"Without a doubt, we would not be able to do these studies without the assistance of parent support groups getting the word out," he said.
While new stem cell technology has vastly increased the research potential of baby teeth, scientists have been collecting baby teeth for research for decades. In 1958, researchers at Washington University in St. Louis began collecting baby teeth to study links between cancer rates and nuclear fallout from the first U.S. atomic bomb tests. Public health officials in Michigan have mentioned collecting baby teeth in Flint to help them determine what children have been exposed to lead from the city's drinking water. And a study published earlier this year found that children from war-torn Iraq had higher levels of lead and other heavy metals in their baby teeth that counterparts from more stable parts of the Middle East.
About a decade ago, Cate Quas, a pediatric dentist with Bluefish Dental in Bend, helped sort teeth for a study at the University of California, Irvine, testing whether prenatal exposure to manganese was linked to behavioral issues. She was asked to identify thousands of baby teeth collected from kids in the study to determine where in the mouth they had grown.
"Teeth form from the tip down to the root, so it's like rings on a tree," Quas said. "At different times, teeth are at different levels of mineralization."
Dr. Raymond Palmer, an epidemiologist at the University of Texas Health Science Center in San Antonio, is collecting baby teeth from families of autistic children in the Rio Grande Valley of Texas to determine whether pesticides might be combining with genetic susceptibility to trigger the condition.
"Rarely is something entirely genetic or entirely environmental," he said. "My problem as an autism researcher has been to identify environmental exposures."
Testing hair, blood and urine can provide data on recent exposure, but autism researchers need to look much further back in time.
"With something like autism, there are windows, critical periods of neural development that we need to know what you were exposed to," Palmer said. "You can ask mothers about their exposure and their use of products, but that's very fallible."
Baby teeth form in the second trimester of pregnancy and begin to create a record of exposure.
"As they develop that enamel, they just sequester whatever is floating around in there, and it stays in there forever," Palmer said. "You take that tooth, slice it in half with very sophisticated equipment, and then you can see rings of a tree. You can date what you find inside these teeth."
Palmer has collected teeth from over a thousand kids in Texas, some from children with autism, some from their unaffected siblings and some from kids who don't have autism. The researchers are interested not only what compounds kids with autism have in common but also at what stage in their development. They have also been able to scrape the pulp out of the teeth to get DNA samples they can then use to consider both exposure and genetics.
"It's a one-stop shop for what you've been exposed to and for genetic information," he said. "You're not asking a question. It's hard data."
Biological hard drives
Palmer has been collaborating with Dr. Manish Arora, director of exposure biology at the Icahn School of Medicine at Mount Sinai in New York. Manish, who originally trained as a dentist, grew up in a region of Africa that had experienced civil war and abundant use of pesticides. He became interested in environmental exposure.
One of the major challenges was "trying to figure out what someone was exposed to before they were born," he said. "On the surface, it seemed like an impossible problem."
He could ask mothers about potential exposures, but that was subject to recall problems. That's when his dental training kicked in. Researchers had been grinding up teeth to search for heavy metals or radiation for years, but that would only give them a sense of what compound they had been exposed to, not when.
Arora learned new techniques from nuclear physicists and structural chemists that used lasers to map chemicals at the microscopic level.
"The amazing thing about teeth is they're made up of this stuff called hydroxyapatite. It's highly reactive," he said. "It will trap a lot of different chemicals."
Every tooth was essentially a record of the environmental exposures that occurred as that tooth was developing, or in Arora's parlance, a biological hard drive.
Like the strata of earth that contain clues to the lives of the animal and people alive at the time, the layers of teeth record an individual's various exposures.
"It can capture the information and keep it safe," he said.
At first, Arora started looking for lead exposures, but has now been able to find organic compounds, pesticides, pharmaceutical drugs, compounds in sunscreens, even the chemical BPA. Manish recently published a paper showing they could find more than 10,000 unique compounds in a tooth.
The biological hard drives were a wealth of information. Arora developed a way to determine when a mother stopped breast-feeding the child. One colleague asked him to analyze a Neanderthal tooth more than 100,000 years.
The analysis was able to show that the Neanderthal's mother breast-fed him for seven months, then weaned him for another seven. Humans in nonindustrialized societies breast-fed for an average of 2½ months.
Arora is helping researchers study whether supplementing baby formula with iron may be linked to the development of Alzheimer's disease or Parkinson's syndrome.
Tooth: Chemical time machine
Arora maintains that using baby teeth could dramatically simplify the research process for rare diseases. Currently, if researchers want to study the link between environmental exposures during pregnancy and a given condition in a meaningful way, they would have to record what pregnant women were exposed to and then wait years to determine whether those children developed the given condition. Because researchers couldn't know in advance what children would be affected, they'd have to enroll many more pregnant women in the study to ensure they had the numbers to make a meaningful conclusion.
For an uncommon but not rare condition like autism, which affects about 1 percent of live births, researchers would have to enroll some 10,000 mothers to end up with 100 cases of autism. To study ALS, which affects one in 1,000 individuals, they need a million test subjects.
Studying baby teeth is akin to researchers enrolling every mother in America in the clinical study, but only running the diagnostic testing on a sample of those whose children developed autism and a corresponding control group.
"This is really like a chemical time machine to be able to look back and address these conditions that have such a huge impact on society, but they take a long time to occur at low frequency," Arora said.
Researchers put more weight into a prospective study, one that tracks exposures first and then waits to see what will develop, than a retrospective study, which starts with the patients and then looks back to determine what exposures those patients had in common. Using teeth is way of doing a prospective study retrospectively.
"If you're doing a prospective study, you collect blood samples every day and you put it in the freezer. You would call that a prospective study even if you analyzed all the blood samples at the end of the study," he said. "This is like a freezer in your mouth. It's collecting all the information and keeping it safe for you to analyze it at the end."
Rather than specializing in one disease, Arora is focusing on the techniques to analyze tooth enamel, and collaborates with various disease experts considering environmental causes of disease.
"What I would like to do is to help a lot of people working across a lot of different diseases," Arora said. "The method is very versatile and can be applied to so many different things."
— Reporter: 541-633-2162, email@example.com


text:
Here's what you found at your local farmers market last week using the hashtag #F52farmstand.
Some "sassy" cauliflower captured by Assistant Editor Caroline at the Union Square Farmers Market:
Griotte cherries in Brooklyn:
An unbelievably adorable sunflower stand in East Hampton:
Plums on plums in Ballard, Seattle:
We're seeing red at the Foothills Farmers Market in Auburn, California:
Have you seen beautiful produce popping up at your local farmers market? Share it on Instagram with the hashtag #F52farmstand and the location it's from for a chance to be featured here next week!

subset: commoncrawl


text:
32GB Samsung SD Card Shows Damaged and Needs Formatting on Android Phone
"Hi, everybody! Yesterday, I was moving some birthday celebrating photos from my Samsung Galaxy android phone on my Windows 8 laptop. Since I was also playing a game there during the data transferring, this Windows computer crashed suddenly and managed to hide all my pictures stored inside this Samsung phone memory card, a 32 GB Sandisk SD card. No selected android phone photos could be found on the partitions of this CP and this phone SD card. The computer recycle bin was also empty. Do you know where my android phone card photos were go after that PC crash? How to recover Samsung Galaxy data from SD card?"
Hello, friends! Sudden computer crashing happens to people from time to time, especially when you do have running too many programs, games or processes at the same. Hence, never try to play a game or program that could occupy much computer resources next time during data moving. And, in your case, though your android phone SD card photos get disappeared due to that sudden PC crash, you may still have chances to recover Samsung phone files back with the help of phone memory card recovery software.
Generally, as a android phone user, you probably has been suggested not to rudely remove or extract phone out from computer during data transformation before, right? Why? Any sudden extracting or removing could damage your phone data and cause android phone data loss troubles. And, like that, sudden computer crashing during the data moving also will corrupt your Samsung android phone. Hence, after your Windows 8 computer crashes, your Samsung Galaxy phone and inner used Sandisk SD card are also damaged somehow. And that's absolutely why you cannot see any phone photo there. But, also no worry. Your phone SD memory card may not completely corrupted and dead yet. Merely perform data recovery processes there to take your lost phone photos back and format it there to restore its functional use.
In your case, no matter why you cannot find photos stored inside your Samsung phone memory card after PC crash and whether your android phone SD card is damaged due to that sudden computer crashing, you are supposed to do a data recovery scan on this phone memory card with the help of android phone memory card data recovery programs and recover lost photos and files as possible as you can.
And before this 32GB phone memory card is really corrupted or completely rewritten by new information, you can use the below photo recovery program and follow the tutorial to recover deleted files from Android free:
Step1. Search and download android phone data recovery software based on your own conditions.
Step2. Run the installed software and select fixable data recovery modes to perform data recovery scan there.
Step3. Preview the found SD card photos and files to see whether this software is useful for your case.
Step4. Recover your Samsung galaxy mobile photos and files to computer hard drives well.
Please Attention:
*Preview the scanned files carefully before you decide to purchase a code of data recovery software.
*Select computer hard drive or partition, not this Sandisk SD card, to save retrieved phone data in case of data recovery failures.
*Make phone data backups on several memory cards, drives or locations timely in the future.
Here are several things you can do to fix possible computer issues after sudden computer crash:
1). Reboot your computer to restore its functional use.
Generally, computer could suddenly crash due to some temporary issues, like low memory, high usage, overheating or more. Merely restart your computer to fix everything.
2). Check computer hard drive to see whether there are some problems.
Sudden computer crashing problems also happen when your computer hard drive gets corrupted, have too many bad sectors or has no enough free space and more related causes. Go check your phone drive carefully.
3). Scan and remove viruses.
Just scan and get rid of all possible viruses hidden on your computer.
And there are also many other reasons and solutions for the related computer crashing problems. You'd better search and learn more over the internet. Overall, no matter what happens, always save computer and phone data backups well to avoid unwanted data loss troubles.
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We have already informed that Balayya's 99th film has confirmed and it is going to be directed by Sriwass. Currently, pre-production formalities are taking place at fast pace. Anjali has been chosen to play the female lead already by the makers and now, makers are looking for another actress to …Read More »
'Bharatheeyudu' sequel is likely to happen
Did you remember Shankar's Bharathiyudu where Kamal Haasan, Manisha Koirala and Urmila played the lead roles that was released in 1996? AM Ratnam has produced this film in Tamil and Telugu. Now, A M Ratnam is looking forward to making its sequel soon. Speaking about the sequel, A M Ratnam …Read More »
Sameera Reddy delivers a baby boy
Actress Sameera Reddy who entered into wed-lock with businessman Akshai Varde in January 2014 has been blessed with a baby boy on Monday at private hospital. As per the reports, both mother and son are doing well. She was part of many super hit films in Telugu, Tamil and Hindi. …Read More »
Sukumar's nephew will foray into films
As per the information, Sukumar's brother son Ashok will be making his debut into films very soon. In fact, shooting of the film has been completed and post production activities are taking place at the fast pace. In fact, Ashok worked under Sukumar as assistance director for the films like …Read More »
Gabbar Singh 2 team to leave for Pune
Much delayed project Gabbar Singh 2 is finally hitting the floors on May 29th in Pune at a small village. We know that makers have scouted for locations in Maharastra so finally they have finalized its shoot in Pune. Bobby is helming this project while Anish Ambrose is playing the …Read More »


text: tag:blogger.com,1999:blog-34561822018-08-28T03:47:06.078-04:00as seen through the firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-72213388827679679852013-05-08T14:12:00.001-04:002013-05-08T14:12:52.825-04:00Living Room MakeoverWhen I first bought the home, the living room was painted a yellow color. Which was ok, sort of. But there were so many holes in the wall when I removed the nails and screws. And there was a spot that was painted a different yellow. Since the kitchen was redone, and the living room was right off the kitchen, I figured I might as well keep going. So on Sunday I gathered two friends and we email@example.com:blogger.com,1999:blog-3456182.post-74767406506581215002013-05-03T16:22:00.001-04:002013-05-03T16:22:42.609-04:00Color shiftIn the midst of all the renovation / moving nonsense, I need just one space where I can close the door and relax. That will be my bedroom. I took a vacation day to get my room set up. First, paint the trim. I changed it from a dingy off-white color to a bright white. You can see the drastic difference. Then I painted the room a lighter color. Even though this photo was taken before I had email@example.com:blogger.com,1999:blog-3456182.post-8097785532404781522013-05-01T14:08:00.000-04:002013-05-01T14:08:23.714-04:00Moving Day I moved my stuff out of my apartment this weekend. After looking at the pictures, there was a lot more stuff than I thought. Saturday began with my good friend Jane arriving with her huge SUV to help cart boxes over to the house. If it was in a box or a plastic bin, and we were able to carry it, then we shoved it in her SUV or my car and drove it over. We did two trips. Then firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-17376610185385354412013-04-30T14:15:00.000-04:002013-05-08T14:16:21.264-04:00Day 19: Kitchen RemodelI am so close to the end. I took a vacation day on Tuesday so I can gain some sanity. I was handing over my key to the apartment and still had to clear out the remaining crap. My house was still a shambles and nothing was set up. The electrician came to finish his piece of the insane remodel puzzle. Now my lights work and whatever crappy, illegal, hack job wiring that was done in my crawl firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-87313628816441540572013-04-26T14:50:00.000-04:002013-04-26T14:50:00.732-04:00Day 12: Kitchen RemodelDid a drive by yesterday and the last of the cabinets pieces are in. How I feel about it. The flooring crew kicked out the contractors before they could install the crown molding and kick stops. Getting the floors sanded and finished is the critical element here. email@example.com:blogger.com,1999:blog-3456182.post-31899417925323303442013-04-25T13:34:00.000-04:002013-04-25T13:34:25.934-04:00Day 11: Kitchen Remodel - CabinetsThey're here! They're here! My lovely Martha Stewart knock-off cabinets are here! And they're getting installed! When I checked in on the house last night, here's where they left off. I"m loving the glass front wall cabinet in the corner. firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-46578091047683794762013-04-25T13:29:00.001-04:002013-04-25T13:29:21.034-04:00Day 11: Kitchen Remodel - Floors!The critical piece to me moving in my furniture in this Saturday is to get the floors done. Sanded, refinished, dried... done. The small repair area between the two bedrooms is complete. This once was the location of we think was a floor grate. It might have been something used to pull hot air out of the home. Anyway, the previous patch job sucked and now its gone. The sanding equipment is firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-86422142591200404872013-04-25T13:22:00.003-04:002013-04-25T13:22:54.134-04:00Day 11: Kitchen Remodel - Electrical It's been a week since I posted about the kitchen. After a few days of inactivity that caused some nervousness, there is a flurry of activity at the house again. The electricians arrived and started making holes in the walls at proper counter height. And that crazy old fuse box in the kitchen that still had some knob fuses has been removed. And all those extra fuses have been firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-25608473055122264392013-04-17T12:04:00.000-04:002013-04-17T12:04:10.080-04:00Most annoying dogYesterday I worked from home to let my poison ivy-ridden body heal. And because I was actually working and not taking a day to spend with Barry, he got a little lonely. When he gets bored and I'm not paying attention, he does things to get my attention. Like climbing on to my closet shelf. Or tossing things out of boxes to sit in them. Or trying to squeeze in really tight spots. I bet firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-9347267377756155292013-04-17T07:29:00.001-04:002013-04-17T07:29:43.763-04:00Day Four: Kitchen Remodel I have floors! Lovely, oak floors that will match the rest of the house. Next in, the electrician and the floor guy to sand down the rest of the house and then refinish everything. email@example.com:blogger.com,1999:blog-3456182.post-55404997719342174862013-04-14T10:27:00.000-04:002013-04-14T10:27:06.462-04:00Day three kitchen remodel It's the third day and lo and behold, the sub-floor is cleared and the hole in the floor has been repaired. The wall has also been added. The shell of the kitchen is now complete. On deck are the hardwood floors that will occupy the kitchen. The floors throughout the house will be sanded and then the entire house will be finished together. Yeay hardwood floors. Boo price tag. firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-17000466455491905432013-04-12T08:38:00.001-04:002013-04-12T08:38:14.194-04:00Day Two: Kitchen RenoIt is a form of torture being at work, just two miles away from the house, knowing a transformation is going on. It was especially difficult this day because my attention was shifting from the house, to the poison ivy blisters. None of it was on my actual job. I was thankful when it was 4:30 and I could drive over to the house to see the progress. There is a clear sub-floor and the hole in the firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-67505100332790356362013-04-11T08:11:00.000-04:002013-04-11T08:44:31.674-04:00No going backNow the truly HGTV portion of my home-buying experience begins. The kitchen renovation. Gone are the handmade cabinets. Gone are the layers of linoleum tiles. ] Instead it looks like this guy was let lose in my house. Update: Here is the pile of cabinets and kitchen sink that will be donated to the Habitat for Humanity ReStore. Gotta pay it forward. email@example.com:blogger.com,1999:blog-3456182.post-30807075401602523102013-04-10T08:27:00.000-04:002013-04-10T08:27:49.661-04:00A battle of wits I took a closer look at the ivy growing on the tree and all along the fence line. The good news is that it looks like English ivy. The non-poisonous kind. But that doesn't mean that poison ivy might not be lurking there. The bad news is that I really can't go all willy-nilly with the Round-up because that will kill everything. And while I really don't want ivy all over the place, I firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-2897274229986808722013-04-09T08:48:00.001-04:002013-04-09T08:48:22.230-04:00A battle against ivyIt's been a few days since the closing and it's only in brief moments where the realization sets in that I bought a house! I spent the weekend clearing out the overgrowth of ivy and the three years worth of leaves that have built up along the house. At first glance, those hedges on the right look full and lush. But that would be a lie. It was intertwined with ivy and suffocating firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-64368980516639848492013-04-04T12:12:00.000-04:002013-04-04T12:12:10.660-04:00Sign hereThat's it. The first part of my home buying journey is over. The papers are signed and the keys are handed over. Small mishap for the buyer because he got married between now and when he put the house on the market. Maybe he should have let the lawyer know because his wife has to sign the papers too. Minor inconvenience. Doesn't affect me. She has to sign the papers later today. So now I go email@example.com:blogger.com,1999:blog-3456182.post-53121885237795845222013-03-27T12:15:00.003-04:002013-03-27T12:19:49.076-04:00My Name is DurhamIt's finally all set. I close next week. Sure it's a week later than originally planned, but at least it's happening. I found this movie clip about Durham. It makes me happy that I'm going to be a part of a community with such history. This video was taken around 1949, about 8 years before my home was email@example.com:blogger.com,1999:blog-3456182.post-75618902870949671172013-03-20T08:21:00.001-04:002013-03-20T08:25:48.985-04:00Just give it to me alreadyI first signed all my loan application documents on Feb 28. That was three weeks ago. Since that time I have done a lot of waiting. The appraiser came out to the home to provide his assessment of the property now and what it will appraise for after my renovations are complete. The result came back to my loan officer Julie on March 11. At the very end of the day on March 13 I received an email firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-19730276495509664612013-02-28T09:26:00.001-05:002013-02-28T09:28:31.827-05:00Anorexic piggy bankI was just about to go into the conference room at work to do some audio recording for a project that I'm working on, but it's occupied. Oh well, time to blog. Today I meet with my lender to sign the papers and give her a check. All my spreadsheets of 'if I borrow this much then I'll have to pay this each month for 30 years' and W2s and tax returns will be coming with me. I think I've grown email@example.com:blogger.com,1999:blog-3456182.post-32959615143902226642013-02-26T10:12:00.002-05:002013-02-26T10:12:37.257-05:00Take my moneyI got the estimate from the contractor for all the renovation work that needs to be done. Both what is required, and what I want to do with my kitchen. This just got ten times more real. So on Thursday I meet with my lender and sign the loan papers. Good thing that this is all being rolled into my mortgage. firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-54479636161414215072013-02-20T09:13:00.002-05:002013-02-20T09:14:15.399-05:00Kitchen DreamingLet's talk kitchens. Because that is the main visible change that I will be doing to the home as part of my renovation. Currently it's a mess. There is a lot of unused space. The outlets are not properly grounded. And there is this crazy access to get into the hallway that is practically unusable. My vision is to add a wall where that access to the hallway is, creating a U-shaped email@example.com:blogger.com,1999:blog-3456182.post-43153996463701944552013-02-20T08:28:00.002-05:002013-02-20T08:31:52.491-05:00Home InspectionThings have been moving along. I've been tackling this whole process like any project manager should. I have all my necessary items to make decisions in one place, I've been in touch with my lender, Realtor, home inspector and contractor. And all this BEFORE the deal is final. The home inspection happened last week. I called him Monday morning to arrange a time for him to come out to the firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-46862677036193062372013-02-12T11:25:00.003-05:002013-02-12T11:25:54.443-05:00House ninjaWanna know how fast I move? Offer signed last night. Home inspector coming this afternoon. Like a f'ing NINJA! email@example.com:blogger.com,1999:blog-3456182.post-40737259668136864512013-02-12T04:44:00.003-05:002013-02-12T05:24:29.434-05:00Home Sweet Home, Y'all4am again. This is becoming a habit. Well after my offer, a counter offer and a counter-counter offer, the contract is signed. One set of anxieties are over and an entirely new set of anxieties can take its place. The house. It is a tiny little brick bungalow. Two bedrooms, one bath. Eat in kitchen. The closets are bigger than I expected. I can stand inside each one and spin around like a firstname.lastname@example.com:blogger.com,1999:blog-3456182.post-83113480683801736122013-02-09T17:57:00.002-05:002013-02-09T17:58:18.956-05:00Crunching numbersThere are times where I am spontaneous and just go with the flow. Trust in the Universe and let things sort themselves out. This is not one of those times. As my Realtor provided me comps of other homes in the neighborhood which sold within the last 10 months I pulled out my maps, spreadsheets and went to work. I was trying to decide what to put as an offer price for my home. I compared how email@example.com


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Discussion of "Topographic Surveys: Progress Report of the Committee of the Surveying and Mapping Division on Topographic Surveys"
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Serial Information: Proceedings of the American Society of Civil Engineers, 1946, Vol. 72, Issue 10, Pg. 1438-1438
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In my previous post about Laramidia, and in attempting to explain how the plants and trees were able to provide enough fodder for the large numbers of herbivorous dinosaurs that grazed there, I looked at how a combination of climate, physical and meteorological barriers, and the food value of the plants themselves, could have sustained such a voracious herbivorous assault.
And yet, there was another driving force behind the ability of the plants to, not only survive, but to flourish and quickly recover from sustained grazing – and that was the dinosaurs themselves. Animal partnerships, relationships and animal/plant relationships were almost certainly as evident in the past as they are today and the term used to describe the change affected on one species that interacts with another is coevolution.
The concept of coevolution was first raised by Charles Darwin in Origin of Species and has been gradually refined through the years but the theory still comes under intense scrutiny as scientists try and decide whether the evidence presented for each individual example is truly coevolution. In other words, any form of interaction or symbiosis that produces evolutionary change can only be classed as coevolution when substantiated by thorough research and the appropriate phylogenetic analysis.
Having said that, however, there is ample evidence that implied coevolutionary interaction is extremely likely and there are numerous examples around today – bumblebees and flowers are an appropriate example. The effect of one species on another cannot be denied and in its simplest form is very apparent. Entire species have become extinct or virtually extinct because a foreign species was introduced by accident or even on purpose. Examples are legion: grey squirrels driving out the reds in England, possums in New Zealand devastating flightless bird populations and, in Mauritius, even Man eradicated the dodo.
Indirect extinctions are yet another form of interaction that is also far removed from coevolution. The eradication of a species without any thought can have a massive effect, from the smallest invertebrate through to the biggest apex predator – a domino effect if you will. This form of extinction is most likely to affect different species that are extremely dependent on each other or those taxa that are the cornerstone of many niches thus affecting multiple species.
A couple of very simple examples of this include six species of mite that became extinct when the Carolina parakeet disappeared and a vine plant in Singapore that, when it disappeared, took with it one particular species of butterfly that was dependent on it. To demonstrate a possible future scenario, off the coast of California, there is a delicate ecosystem involving kelp, sea urchins and sea otters. These three species are so totally dependent on each other that the fragility of such ecosystems becomes evident.
|Image by Katie Hale
The sea otters keep the sea urchin population under control which, if left unchecked, would completely devour the kelp forests. Without the kelp, a multitude of different organisms would disappear and yet, without a sufficient population of urchins, the sea otter population would quickly crash and decline. This clearly demonstrates the fragility of such ecosystems and dramatically highlights how the extinction of one species can affect so many others.
Partnerships, or mutualism to give it its correct term, are another form of interaction. The most oft cited example of this is the relationship between ants and acacia trees. The ants depend on the acacia for nesting and food whereby the plant provides specialised thorns that provide shelter, special nectar buds that provide food for the ants and leaf tips that are also of a high food value – especially to the larvae. The ants, in return, remove fungal spores from the tree that may invade the acacia host and provide aggressive defence against any herbivore foolish enough to attempt to feed on the tree. This particular example has often been cited as coevolution so amply demonstrates how hard it can be to classify.
All of the examples highlighted above demonstrate how different species affect one another through various examples of interaction. Despite these all being contemporary examples, it does demonstrate that such relationships have existed, almost certainly, from the earliest forms of life right through to the present day. So how does this all relate to dinosaurs?
Bob Bakker, in his book the Dinosaur Heresies, featured a chapter titled Mesozoic Arms Race in which he postulates how both herbivore and carnivore spurred on the mutual evolution of the two groups – in other words, true coevolution. As theropods got bigger to cope with larger prey, the herbivores got bigger still. If it wasn't size, it was armour, horns, teeth, claws, agility, and social interaction – a plethora of derived traits continually evolving to keep the different genera ahead of the game and ensure survival. Those that did not evolve became extinct. This is the classic example of survival of the fittest – natural selection. Evolve or die.
I suspect that trees and plants were also part of this life or death struggle and that their ability to be able to sustain large populations of giant herbivorous dinosaurs was a direct response to intense grazing pressure from dinosaurs. As herbivorous dinosaurs got bigger and their ability to crop the plants, masticate and digest plant material became more sophisticated, the plants and trees had to adapt or become extinct. They had to find new ways to be able to withstand the stress of being constantly cropped, be able to reproduce quickly, and grow at inflated rates.
The fact that there are so many different shaped and sized herbivorous dinosaurs is highly indicative that they were successful. Small ornithopods would graze at low levels, mid-sized animals could take advantage of both whilst animals such as brachiosaurs and titanosaurs could feed at higher levels. Whilst appreciating this is a very simplified way of looking at things, the point is well made. Herbivorous dinosaurs evolved into many different and complex varieties to cope with the continually evolving plants.
In the Cretaceous, things moved on to another level with the evolution of much more complex herbivorous dinosaurs. The well-publicised iguanodont and hadrosaurian dental batteries, which enabled a much more efficient form of food processing, along with ceratopsians, ankylosaurs, sauropods and other ornithopods, pushed plants and trees to new heights of production.
But this time the plants and trees had even more help with an increase in the amount of CO2 in the atmosphere, increased warmth and moisture and this combination enabled the flora to grow at inflated rates. And there was yet one more innovation by the plants to come which aided reproduction, fertilisation and increased diversity and sustainability.
It has been often noted that the dinosaurs may have been responsible for the appearance of flowers during the Cretaceous (eg again see Bakker 1986). Although there is no foundation or scientific evidence to back this assertion, it does appear likely that intense dinosaurian herbivory may have contributed to the evolution of flowering plants (Barrett et al 2001 but see also Lloyd et al 2008).
The truth is almost certainly something in between. The dinosaurs probably prompted rapid development in plants to avoid eradication and extinction. During the Cretaceous conditions were so good for growth that the plants simply took advantage of the situation and evolved extremely rapidly - with flowers simply another tool which allowed further diversity and distribution. This enabled the dinosaurs to feed on an almost never ending supply of fodder and is possibly the chief reason why Laramidia was able to sustain such large populations of big dinosaurs.
Bakker, R. 1986. The Dinosaur Heresies: New Theories Unlocking the Mystery of the Dinosaurs and Their Extinction. William Morrow and Company, New York.
Barrett P.M, Willis K.J. Did dinosaurs invent flowers? Dinosaur-angiosperm coevolution revisited. Biol. Rev. 2001;76:411–447. doi:10.1017/S1464793101005735[PubMed]
Lloyd, G.T., Davis, K.E., Pisani, D., Tarver, J.E., Ruta, M., Sakamoto, M., Hone, D.W.E., Jennings, R., and Benton, M.J. 2008. Dinosaurs and the Cretaceous Terrestrial Revolution. Proceedings of the Royal Society, Series B 275, 2483-2490 (doi:10.1098/rspb.2008.0715).


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ILRI's research program on Livelihoods, Gender and Impact (LGI) is among the five ILRI programs within Integrated Sciences. The program objective is to provide high quality, relevant research that is able to guide research and development initiatives aimed at improving the livelihoods of women and men operating in livestock value chains. Working with other programs, LGI works toward identifying promising technological, organizational and institutional innovations; assessing their likely impact on women and men; building strong partnerships with other research institutes, the private sector and government agencies (including line ministries and local government authorities), and to test interventions in order to assess their impact and potential for scaling.
One area of research pursued by LGI looks at the special case of smallholder farmers' capacities, assets and activities to increase their competitiveness through increased integration in value chains. This is the Smallholder Competitiveness in Value Chains research team which aims at identifying, testing and evaluating technical, institutional and organizational mechanisms to improve smallholder farmers' livelihoods. The second area of research looks at relations between women and men as social construct, and how these could be transformed for improved livelihoods. This is the Gender research team which seeks to understand and respond appropriately to the socio-economic contexts within which both men and women engage in livestock production. The third research area is Monitoring, Evaluation and Learning, which focuses on the development of outcome and impact systems and analysis. The primary objective of MEL is to measure the results of ILRI's research interventions and demonstrate their development impact; and in addition, to facilitate learning among the stakeholders throughout the research programs' phases...Read full profile
This page brings together ILRI and partner resources on Livelihoods, gender and impact. It shows information on projects, news items, research outputs, video materials and presentations as well as ILRI people working on Livelihoods, gender and impact. See where ILRI works; and the research issues it works on.


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The Rookie
The series follows John Nolan, a 40-year-old man who moves from his comfortable, small-town life to Los Angeles to pursue his dream of being a police officer for the Los Angeles Police Department. He must navigate the dangerous, humorous, and unpredictable world of a "young" cop, determined to make his second shot at life count.
Actor: Nathan Fillion, Alyssa Diaz, Eric Winter, Titus Makin Jr
Director: ...
Country: United States
Duration: na min/episode
Quality: HD
Release: 2018
IMDb: 8
Keywords: the rookie


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Please don't shoot me oh, but i honestly believe val's day is way overrated! Any takers?
Please don't shoot me oh, but i honestly believe val's day is way overrated! Any takers?
One more day to show extra attention to your loved one. We love etch other every day, but it is always nice to have special days.
But if everyday is special, then having a "special" special day is kinda redundant.
I love Valentine's Day, it's great a occasion to show attention for person who you care :) I always do a small surprise for my bf:)
i also love Valentine's Day! I know that this day I spend with beloved person and we have a great time in a nice place:)
There is necessary one day in the year that we could present for beloved person our time and attention. sometimes we work a lot or don't have possibilities to give it.
I dont think that Vals day is very special day, so I am not preparing for it at all...
and its not Vals day worth but your love is woth for all your efforts to do your lover happy
agree absolutely with biel peru!
I agree, that love should be showed every day for imporant persons, not only one time per year. If it happens like that, it means that it's not a real feelings, but superficial love.
these times there are many superficial love like as superficial people


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Adam Bate
Comment and Analysis @ghostgoal
Why Atletico Madrid midfielder Koke could be a key man for Diego Simeone's side against Chelsea
Diego Costa is the man everyone has been talking about at Atletico Madrid this season. But Koke has become a hugely important figure too and is a man capable of causing Chelsea real problems in the Champions League semi-final. Adam Bate finds out more...
Last Updated: 22/04/14 9:10am
Barcelona had no answer. Swamped by Atletico Madrid's pressing game, they were simply overwhelmed in a 20 minute onslaught.
The decisive blow in the second leg of their Champions League quarter-final in the Spanish capital was struck by Koke, sweeping home to send the Vicente Calderon Stadium into raptures. Xavi Hernandez, Andres Iniesta et al were vanquished. And given their presence on the pitch, the identity of the scorer felt entirely appropriate. This is Koke's time.
He is a guy with a huge future. He gives us many solutions in games and is an example to the guys pushing from below.
Diego Simeone on Koke (Source: AS)
Xavi is a self-confessed admirer. "Koke is an extraordinary footballer," he said prior to the quarter-final. "He has everything: talent, physical ability, he is a footballer of the present and the future. He has been marked out as the conductor of Spain's orchestra for the next 10 years. I have a special affection for him because we play in the same position and I think he is an extraordinary player."
Xavi's comments suggest that he sees plenty of himself in Koke. And yet, it is long-time partner in midfield mischief, Iniesta, who more closely resembles the Atletico man in style. Collecting the ball on the left of midfield with his favoured right foot and then scheming in search of that incisive through-ball, Koke has emerged as a key figure in the club's rise.
It's all very different from his inauspicious debut against Barcelona in 2009. Atletico were thrashed 5-2 at the Camp Nou with Koke taking time to develop into a bit-part player of promise under first Quique Sanchez Flores and later Gregorio Manzano. It is the guidance of Diego Simeone that has sparked an exponential improvement in both player and team.
He has everything. He's young and has a great future. He can score, tackle, make a great pass to assist and he's physically strong.
David Villa on Koke (Source: FFT)
"The trainer changed and everything changed," Koke told FourFourTwo earlier this year. It's a succinct turn of phrase that sums up something altogether remarkable. Atletico lead La Liga and are three matches away from being champions of Europe for the first time. While the Barcelona of Xavi and Iniesta appear listless, the Atletico of Koke seems infused with energy and verve.
Indeed, the 22-year-old looks a lot like the complete midfielder with the physicality to match his technical gifts. Simeone's side is constructed in the image of their coach and the mental toughness is evident in the No.6. Built upon this prerequisite of unstinting commitment, Koke has taken on a level of responsibility that belies his age.
"Koke is an extremely important player for us, for the way he plays, for the way he interprets tactics," said Simeone earlier this month. "Since we arrived here he has developed a great deal and today he is one of the best players in La Liga. Everything he is achieving is based on his efforts and hard work and that is great for anyone."
I've watched him grow and he's really developed, especially in the last 12 months when he's improved more than anyone.
Gabi on Koke (Source: FFT)
His importance is reflected in the statistics that highlight his role as arch-creator in the Atletico midfield. Whether from dead-ball situations or open play, Koke makes things happen for the team – with Diego Costa the chief recipient of his unerring service. While the striker has 27 goals in La Liga this term, second only to Cristiano Ronaldo, there is nobody with more assists than Koke.
But there is far more to his game than that – under Simeone there is no choice in the matter. As a result, the list of most creative players still active in this season's Champions League is revealing. The names are familiar – Franck Ribery, Arjen Robben, Philipp Lahm and Toni Kroos; Ronaldo, Karim Benzema, Luka Modric and Angel Di Maria. But there is something that separates Koke.
Not only is the Spaniard creating opportunities for his team, he is also one of the foremost tacklers in this season's competition. With 32 tackles, he has far more than all of the players mentioned. In fact, he's made more of them in the Champions League than the aforementioned Real Madrid quartet combined. Leading the high press, Koke is aware he has a dual role.
He's got pure class – a different way of reading the game, with a great final pass. All I can say is thank God he's been assisting me to score goals.
Diego Costa on Koke (Source: FFT)
It's little wonder that Vicente Del Bosque rewarded him with his first senior international cap as a late substitute against Ecuador in August. Koke is now pushing for a starting place let alone a watching brief from the bench. "He's a very complete midfielder and he does virtually everything in that role," said the Spain coach.
Against Chelsea, this adaptability coupled with the tactical astuteness that Simeone cites could prove critical. Atletico's counter-punching style has served them well in La Liga but despite the team's inexperience at this stage of Europe's premier club competition, they go into the semi-final as narrow favourites with the bookmakers.
As a result, there is a tricky balance to strike. Do they seek to dominate with a possession game or adopt a counter-attacking policy of their own? Whatever ploy Simeone opts to go with, there is one certainty: he has a man in midfield who will adapt to the instructions and conduct the orchestra accordingly. After all, as Barcelona know to their cost, Koke is an extraordinary player.


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What gift should I offer to my love on Valentine's day?
Is it almost Valentine's day and you have no idea for a gift? Try our special massage offers valid from 10th to 16th of February! The perfect way to ignite the fire in your relationship with LOVE – Celebrating the most powerful energy in the Universe, the Love two people share together, we would like


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As I mentioned sometime ago, we had plans to go China year end due to the fact that office is closed for 11 days hehe…so we left KL on 25th and came back on 2nd Jan. Kids as usual with grandma and maid. Just 2 of us, the backpackers style.
Our route, Macau-Shenzen-Guangzhou-Zhuhai and back to Macau for flight.
This post gonna be for Macau, hope I have time by this week to put on rest of the places we went…I'm so so so busy with office work :(.
We took the 630am flight on Christmas day. The flight was on time, but departed late..cause there's a lady whom I suspect overslept somewhere in the airport and the whole plane waited for her!!! So we departed late by 15mins…See the woman in the pic that's sleeping, yah that's the fella lahh…The flight was pretty long and boring. I managed to nap for a while, and took some pics of the clouds…very nice clouds..all lining up in rows 🙂
We arrived at the Macau airport close to 11am, the airport is OK lah, nothing special just by the seaside, can see a lot of land reclaiming in progress. The captain that flew us there was Daddy's buddy captain, so I went into the cockpit and took some pics hehhe…
We took a cab and head straight to the hotel, OK, it's a 3 star hotel and it's so so small, the only word Daddy could say is *WALAUUUU*..he repeated this like so many times!!! What to do, backpackers mah, and christmas day, they charge double price, so this the only one we could afford. I booked the hotel from Internet, and for this room size we are paying RM200 a night on Christmas Day!!
We didn't really know where exactly we were, so we called our friend's cousin, Yen (whom is a local there) and she told us we are near town. We got ourselves a map, and started walking. Of course first thing, food!! So hungry. She recommended a shop nearby, which has good wan tan mee. After walking for quite some distance (their road signs are pretty tourist friendly) and asking around, finally we found the shop.
Another walauuuu….you gotta take number to eat!!! So we waited like 15 mins and our turn came. We ordered wan tan mee of course :P. And pork chop bun, supposed to be Macau good food, but not from this shop, but eat lah…then we saw next table order some fish skin, we also ordered hahah…the wantan mee, yummy!! Wantan was huge, and the prawn so fresh. The noodles so fine…aiyoo…I love it. The fish skin was nice too, it's a cold dish, eaten with ginger and some soya sauce. Very crunchy taste as well hehe..
After satisfying our tummy, we started walking around..we were actually at Senado Square. Alot of shops there and so many people. St Paul and some other heritage is also around the corner. We went to one of the Church, St. Dominic's Church..then continue wandering around. Then saw a stall selling *Malt sweets* (mak nga tong), my childhood love :). So we bought and ate it, very nice and soft…We also passed by a shop selling crocs, they had kids crocs shoes featuring disney, so cute but expensive lah. Macau is also famous with almond cookies…we see them all over the place!!!
After walking for 2 hours plus..we head back to hotel to take a rest. Our plan was to go for tea exhibition at Lou Lim Ieoc Garden, then at night we will go for street concert at St Paul's Ruin. We took a bus and stopped nearby the Garden, and walked there only to find out that the tea house is under renovation…grrrr…nevertheless, the garden was pretty beautiful so we went around and took some pics (the people playing chess & old lady doing taichi)..then we decided to take a walk to this place we passed by earlier where we saw the cable car…didn't know what was it, just kepoh…
We took the cable car up, just in time, they closes at 6pm!! Well, it was another park!! Really huge right on top of the hill..and then we found out that it was actually where the Guia Fortress & Lighthouse were!! And since Daddy likes Lighthouse, we decided to go for it. It was quite far to walk at the park itself, but the scenery was breathtaking. And the lighthouse was very beautiful too hehe..worth all the effort lah!!!
It was already dark when we arrived there (winter time, day is shorter). We took a walk downhill based on the map, St. Paul Ruins is not that far..so we just walk n walk n walk LOL. Took some photos of a supposingly sports center…and finally when we found St. Paul Ruins, we were cursing one lady that gave us wrong direction. It took us like more than 30mins to walk, luckily the weather was cooling, so it's not that bad.
It looks beautiful..but nothing much to see lah..just a ruin LOL. We thought the concert hasn't started, so we went downhill on the way to Senado Square and had McD haha…yes, we eat McD everywhere we go, cause that's the safest thing and they have diff menu. So happen they have this rice burger (rice, patty/beef slices, rice). Yummy!!!
After that we walked back to St. Paul Ruins only to find out that the last concert was on 24th Dec..duhh!!! So we just sat there, took some pics and relax before walking back to hotel again. On our way, we saw this shop, very famous I think (It was so so crowded), selling bakwa..they have so many varieties, even Ostrich meat!!! We bought some for MIL to try.
Took a pic of Senado Square at night..beautiful eh with the lights deco. While walking back, we stopped by a chinese medicine hall, buy some sour plum (see the pic, they are so free hoh, arrange the sour plum so nicely haha).
Next day, we had a date with our private tour guide, Yen :). She met us at the hotel, and took us for porridge breakfast, walking distance from our hotel as well. Very famous porridge slurpss!!! It all comes with huge meatball…plus other stuff depending on what you order. I ordered meatballs with egg and some pig spare parts. Daddy had meatballs only.
After that, we hop on to Yen's sister car and started our Macau day 2 tour. We told them where we went yesterday and they were like…whoaa..you walked from Guia Fort to St. Paul…it's bloody far!!! LOL..backpackers mah, like dat lorr..
Our first destination, A-Ma Cultural Village. This is where the A-Ma statue is, supposingly the goddess of fisherman where most Macanese worship. From here, we can see the whole of Macau, since it's the highest peak in Macau (if I remembered correctly). See the first pic, there are a row of houses by the seaside…very nice bungalow, we took a drive there later on on our way out hehe…
Next, we stopped at Coloane for some hot pipping-freshly-baked Portuguese Eggtarts, Lord Stow's Bakery. I never tried Portuguese Eggtart before, even in KL though I'm an eggtart lover. We bought 4, and added some cinnamon powder on it. Across the road, there were actually some marble chalrs and table for us to sit and enjoy the eggtarts. Look at Daddy's face hahaha…it's really delicious..the egg melts in the mouth and the crust so crispy. I had 2 LOL.
Then Daddy wanted to get some salted fish for MIL, so we went to a shop nearby, supposingly all the tourist goes there for salted fish. Look at the oyster, so so huge!!! And also the stretch of salted fish hehe…
We walked around that area and there was another old heritage, forgotten what's the name..I think it was a very old temple, like the first few in Macau. We then went for late lunch at one of the shop, famous also (see picture for the name). Ordered their kam hiong lala (macau style), salted fish steam with pork (macau style also) and steam fish and veg. Yum yum…the lala was different, more spicy. Minced pork with salted fish, very nice oso hehe…
On the way out from Coloane, we stopped by at the Black Sand beach…the sand is very black, naturally. They had BBQ seafood along the beach, I bought cuttlefish to munch (I'm eating so much aiyoo). Then we went to the Taipa Houses Museum. There were like 4-5 houses, depicting the Portugese lifestyle when they were in Macau. They also had some ceramic exhibition in place at the same time. The last pic is a photo of me with our tour guide, Yen. It's really nice of her bringing us around. Next time she comes to KL, we must bring her around also hehe…
While we were there, we caught a couple taking wedding photos there hehe…I suppose this must be one of the good location for outdoor wedding shoot. And also a couple I think just proposed to each other!!! The girl was holding 99 roses!!! Both Yen and myself were like wahh wahh…how many roses ehh…LOL.
After that we head for our tea time snack..oops..not snack, it was quite heavy actually. Some fish soup with noodles, Yue Tong Fun. I quite like the soup, very peppery..nice to drink during winter..but Daddy didn't quite like it hehe…besides the soup, I also ordered a bowl of noodles with pig's ears.
Then we went to the harbour to get tickets to HK since next day we will be going there. Manage to stopped by Post Office to check out their FDC collection, but didn't buy any though. We picked up Yen's friend at the harbour as well (Japanese girl speaking English), and then head straight to this Church…ermm…can't remember the name again. It was on top of the hill and we just made it before they close the gate haha…Apparently, the *Shanghai Beach – famous TVB series* was filmed here..so Daddy also did a Shanghai Beach pose..the church was where they got married..maybe??
There were also a water fountain at the foothill of the church. And of course, from there we can enjoy the scenery of Macau…looking at one of the bridge. Very nice hoh…We also passed by Stanley Ho's house (first pic on the left) and I papparazzi-ed his house hahaha…
We head for dinner, by then I think about 8pm liao (it gets dark so early, we can hardly tell the time). The restaurant name is Hung Kee. Local foodfare.
Huge chicken wings, Pak cham kai with siu yoke, Corn soup with fish maw, Sotong with Celery (my favourite, cause I like celery hehe), Steam egg with crab meat and of course the exotic, worms cooked with dunno what, looks like omelette to me. There were 7-8 of us (whole of Yen's family, 3 sisters), lucky thing we managed to finish the food.
After dinner, they took us to walk around Taipa Village. There were alot of shops selling food and they offer free sample for you to try. So if you are hungry and no money to eat, here's where you go LOL. I like the jelly, very nice and different from what we have here (no photo, too busy eating).
We next head to Fisherman's Wharf. This is the new tourist attraction spot in Macau, just opened in 2005. Ooh..I just love this place, it's next to the Sands Casino Hotel, and the lights at night makes this place very beautiful.
It has got loads of shops depicting different designs (Holland, Japan, American, etc.). The shops were either restaurant, hotel or souvenir shop. It even has a Roman Amphitheatre. We spent more than 45 minutes here, admiring the place…love the lights and the cooling breeze.
On our way back to hotel, Yen's sister drove pass Lisboa, the famous casino. Apparently, there will be more Las Vegas casinos opened in Macau by end of this year. One of the new one is Sands (you can see it when landing from the plane). The other ones are still in construction, but it's huge!!! One of it has a river insider the hotel itself…whoaa…and to counter this, the old Lisboa came out with a new Lisboa haha..just opposite the old Lisboa, huge!!! The pic on top is the new Lisboa, still under construction but they already putting on lights. And on top of it, it's a Y shape hotel..so tall!!
So that's all for Macau. If you ask me if I'll go back again, definitely, since we didn't go into the casino LOL. Wait till all the new casino is up lah, then we go again hehe..with MIL maybe. I enjoyed the food there and the people are friendly too.
Next day, our destination is 1/2 day HK, 1/2 day Shenzen. Stay tuned ;).


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Since I dedicated last week to my home tour (living room, dining room, kitchen, bedroom, dressing room, bathroom), it's taken me nearly a week to share this outfit from last Tuesday with you. Let's catch up, shall we?
I love this blazer; it's just so easy to wear. All I have to do is add some colored denim and some jewelry, and I look pulled-together with zero effort. That's the kind of piece we all need in our wardrobe for those completely uninspired Tuesdays.
Two-tone blazer - Anthropologie
Plum jeans - AG, Anthropologie
Gray tee with leather sleeves - Zara
Quilted leather boots - Corso Como, Nordstrom
Nameplate necklace - custom
Bauble necklace - eBay
Claw bracelet - Asos
Pavé cable bracelet - J.Crew
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A blog by Vitessesteve mostly about Triumph car stuff. Featuring articles about Standard Triumph car dealers. Includes new free technical literature such as Parts Catalogues, Workshop Manuals and Owners Handbooks.
Thursday, January 23, 2014
Its covered
Fitted my new Specialised Covers Stormshield cover over my TR7 Sprint convertable. Looks to be an excellent product. Fits very well, they made it to fit over my non-standard Honeybourne Mouldings hardtop.
Only problem I can see is that to use the straps that pass under the car I have to lie on the ground to pass the straps under the car. Car gets new cover and stays snug under its cover but I get wet and or dirty laying on the drive to fit the straps.
There is enough room under the cover for the stubby radio aerial on the rear wing to be folded down. I was offered the option to have Velcro slot for the aerial to poke throu the cover. I like the contrast colour for the door mirror pockets.
PS This blog features on the Club Triumph website along with many other Triumph blogs. I got a helpful suggestion from there - use an extending metal measuring tape under the the car to pull the strap from one side to the other.
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Komori America Inks Deal At Graph Expo For First System 38S Web Press In NA
Wednesday, October 27, 2004
Press release from the issuing company(October 26, 2004 Rolling Meadows, IL) Prodigy Graphics Group, Brampton, ON, signed a purchase agreement for the first North American installation of the Komori System 38S web press. The System 38S, a full size, 16-page web press, made its exhibition debut at Drupa 04. Stephan Carter, President and COO of Komori America said, "We are very pleased that Prodigy Graphics Group will be the home to the first System 38S in North America. The System 38 received high acclaim at Drupa and we are confident that this will be the first of many installations in North America." Prodigy's version of the System 38S is a four unit press that features a 23 9/16" cut-off, and is expected to deliver in 2005. Steve Ranson, VP of Sales for K-North, Komori's Mississauga, ON based dealership said, "We're excited to place the first System 38S in Canada. Prodigy is a very successful printing plant, and the new web press will be a great addition to their operation." The System 38S provides the world's shortest changeover time through fully automated one-step register adjustment, color matching, fold adjustment and plate changing. Komori's new KHS-AI with Advanced Intelligence has self-learning software that further reduces job changeover time, costs and workload. The JDF compliant System 38S runs at speeds of 60,000-iph, and has a new folder that handles a variety of products, including direct mail, advertising material, and magazines. Prodigy Graphics Group was founded in 1976 and is housed in a 150,000 sq. ft. facility close to Toronto International Airport. Prodigy has grown from a small duplicator shop to a full service printing facility with 100 employees and over 60 offset printing units. They provide their customers services from prepress through fulfillment. The System 38S will be Prodigy's first web press. K-North, Mississauga, ON has represented Komori products in Ontario and Western Canada since 2003. Komori Corporation, headquartered in Tokyo, Japan, is a premier manufacturer and worldwide distributor of offset printing presses. The Company has manufacturing facilities in Toride, Sekiyado, Yamagata and Tsukuba, Japan, and subsidiaries in Europe, the UK and the United States. Komori America Corporation is based in Rolling Meadows, Illinois, and manages a distribution and service network throughout the United States.
Industry News
Copyright © 2019 WhatTheyThink. All Rights Reserved


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Maybe it was my Dad's upbringing and how his parents survived the flu epidemic of 1918, but he's a germ-o-phob (is that how you spell it?) My wife freaks out about germs too. So maybe all of this has rubbed off on me … maybe I've been infected.
Today was the day the germ broke this office-worker's back. There is this man who works at my office who doesn't wash his hands. He has a mullet, a beard, wears those ugly brown loafers with the tassels and he doesn't sport a belt. To finish off his ensemble, he coolly wears a gold braclet and necklace. This guy is really cool. He belongs in Nashville singing on Yee Haw.
I've been in the bathroom for number one when he walks in. I finish first and then wash my hands with steamy hot water and lots of soap. My hands are so clean, I'm prepped for surgury. While I'm drying my hands, this perv nonchalantly walks past me, pauses in front of the mirror to admire his mullet and then exits the bathroom! What the hell!?
Plastered on the mirror are signs urging people to wash their grimy hands.
He's the reason why I carry my paper towel with me all the way back to my desk. There's no way on earth that I'm going to touch the doorknob this hobo defiled. His hand was touching his junk; his hand then touched the doorknob, therefore his junk is all over the doorknob.
As bad as an offense he committed without washing after number one; it was nothing compared to the total disregard of the strict rule of washing after number two. Yep, that's right. Today while steaming up the mirror with scalding hot water and scrubbing the skin off my hands, I watched Mullet-Man egress a stall and walk right past the sinks! Just as he was about touch the door handle, I yelled out, "HALT YOU DIRTY BASTARD!!"
He was caught off guard a bit. The water was still running; he was looking at me with his brown-smudged hand inches from the steel bar of the door. It was a show-down at the OK Corral Bathroom. "You get your smutty hands back in here right now and wash em!"
"Oh yeah? What you gonna do if I don't?" he smirked back.
"I will get on the public announcement system and tell the whole damn company that ol-dirty-dick-hands left the bathroom without washing. You'll be an outcast."
He replied, "I dare you."
"Touch that door handle and I will."
His eyes met my eyes. Steam was filling the bathroom. A bead of sweat emerged from his forehead and rolled down his face. I was as calm as a hot summer day in Texas. Both of us were waiting for the other to draw.
"You ain't gonna do it" and then he pulled the handle and walked out.
I shut the water off, dried my hands and then proceeded to the PA phone to make an annoucement.
"Attention. May I have your attention. Billy Ray Roberts has just been to the little-boy's room to make a deposit. He left the bathroom without even glancing at the sink. His hands are highly contagious. If he comes to your office, get out the Lysol. Thank you!"
The rest of the day, my co-workers avoided Billy Ray like the plague. He was an outcast and shunned from all social contact.
Today, my fellow germ-o-phobes, we have taken a step closer to a cleaner world.


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Sunday, 20 March 2011
Mac Full Fuchsia with Sunny Weekend Snaps
As the sun popped out this weekend I dedcided to go out for a walk and enjoy the sun while its out those of you who know me must already know I love my bright pink lipsticks espicially during spring or when summer is just round the corner. Whenever I wear bold or dark lipsticks I usually like to keep the rest of my make up quite neutral and let my lips do all the talking ;)
On my lids I have applied Mac Studio Fix Powder. And Benefit Hoola as contour with Benefit Dallas to the apple of my cheeks. I also grabbed this gorgeous fuchsia capri trouser from Zara I couldn't help but fall in the love with the colour its not that bright but I guess in the sun it came out pretty bright I dont mind too much as I love pink! ;)
Onto the Snaps Enjoy ;)
19 comments:
- Simply R1y4* said...
love the look love the PINK!
- 20 March 2011 at 19:15
- *www.vikki-gabrielleworld.blogspot.com* said...
gorgeous look, i have some pink skinny jeans abit like yours but I haven't been daring enough to wear them in the 18mths i've had them but you have inspired me LOL!
You hair is sooooo frickin gorgeous too xx
- 20 March 2011 at 19:16
- Hell Notes for Beauty™ said...
Nice outfit! Today is the first day of spring and I went out for a walk and it was so lovely. Your hair is amazing too,love it!
- 20 March 2011 at 19:32
- Neena Jay said...
Hi Mevish...
love the hair.... true Indian hair
i'm ur newwest follower...
follow me too at neenajay.blogspot.com
subscribe to me at youtube channel
- 20 March 2011 at 19:41
- Amina said...
u look fabulous hun!! ur hair is soo long im propa jelous!!! lucky cow lol loving the bright pink on u!!
- 20 March 2011 at 21:12
- ParisLola said...
I loooove the pink leggings on you look so hot in them. What do you use for your hair? cus its amazing nice long and thick full of incredible shine xxx
- 20 March 2011 at 21:29
- Marymakeupforever said...
I want those leggings super cute and sexy x you look gorgeous :D
- 20 March 2011 at 21:40
- Marymakeupforever said...
I shall be leaving for zara tomaro even though I'm broke you made me wana grab those heheh
- 20 March 2011 at 21:40
- GingerlymacLove said...
Full fuchsia looks the sex on you very hottttt I love your sense of style very ker-POW unique love it thanks for sharing ;)
- 20 March 2011 at 21:45
- sexyliparazzi said...
The pink lips and leggings loook boom on you so beautiful x
- 20 March 2011 at 21:54
- Alisha's Fashion & Beauty Blog said...
your hair is to die for! gorgeous girl...mashallah
- 20 March 2011 at 23:34
- Rakhshanda said...
very pretty pics...fuchsia shade suits you well...lovely post dear.
- 21 March 2011 at 05:19
- Sami said...
LOVE the pink lippie! And love the trousers too ;-) x
- 21 March 2011 at 14:24
- Natalie said...
You look gorgeous! Your hair is sooo BEAUTIFUL! LOVE the pink trousers! They fit you perfectly!
THank for sharing.
- 21 March 2011 at 15:58
- The Beautifier said...
Love your fuchsia capri trouser and boots!!
- 22 March 2011 at 13:55
- Get Gawjus! said...
would not be able to pull off fuchsia bottoms in my wildest dreams lol. you look awesome though!
- 22 March 2011 at 21:23
- Ik said...
I LOVE your hair!! Like SUPERLOVE!!!!! <3
- 27 March 2011 at 17:23
- Mary said...
I want those bottoms so sexy and i love your hair its amaziiing
- 29 March 2011 at 12:35
- NickiBaby said...
so pretty x
- 29 March 2011 at 12:48


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Why you should correct for barrel distortion
Why you should correct for barrel distortion
Originally uploaded by Seb Przd.
Fortunately, quite a few tools are available to correct for this predictable type of distortion. I use clens, a command-line utility distributed with panotools, with the lens profiles that come with PTlens, a windows alternative to clens (you can find the database in panotools or here).
The top image above is a straight grid, as shot. You can see the curves that should be straight. The bottom image shows the automatic correction with clens, with the lens profile from PTlens.
clens is run like this:
clens -p profile.txt -s nona -l "Nikkor 18-200mm f/3.5-5.6 G ED-IF AF-S VR DX" image.jpg
If it run like this:
clens -p profile.txt -s nona --Lenses image.jpg
it outputs a list of possible lenses, according to the make of the camera and the focal length.
The correction is not perfect, since the Nikkor 18-200mm shows a more complicated (higher order) type of distortion that clens cannot correct for.


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ain't. Actress turned feature film director Sally Field may be
proclaiming "You like me! You really like me!" behind the
camera, but don't be egged on. Here's yet another beauty pageant
drama that cooks up lumpish clichés and a syrupy sweet ending that
will leave you gagging -- and shaking your head in disbelief.
When someone as self-centered and darkly
cynical as Illinois-bred Mona Hibbard (Minnie Driver) decides to
make it her sole ambition in life to win the Miss American Miss
contest at nearly any devious cost, she alienates her blue collar
mother, an unemployed, beer-gut of a stepfather, an unforgiving
audience, and all her friends except one (and she ends up in jail).
Actually she has just the one friend. No surprise there. As a
twelve-year-old, played by Colleen Rennison (and looking like a
young Anna Paquin), Mona disposes of one prissy rival (who later
stages a mean spirited revenge scheme) in a talent segment by
smearing instant glue on a baton set aflame and stuck in the
contestant's grasp. The ne'er-do-well further serves up a dose
of faux heroics by dousing the startled competitor with a handy fire
extinguisher. Seems Mona can't win anyway, other than a
"participant" medal during one contest officiated by Kathleen
Turner as a Southern-fried stage mother. And, although the various
pageant officials can't prove it, when Mona's nearby a scandal
isn't far behind.
Then comes the big whooper. She's
promiscuous. She has a kid, Vanessa (Hallie Kate Eisenberg). Out of
wedlock. As that's a no-no in the Roberts Rule of Beauty
Pageantry, Mona somehow persuades her best friend Ruby (Joey Lauren
Adams), a caring but mentally diminutive nurse to raise the girl as
her own. Skip ahead and the twenty-six-year-old can finally taste
her dream after seven years of back-stabbing and duplicity, when as
Miss Illinois Miss America Miss (Say that ten times quickly. Go on.)
she's two months away from national victory. As the contest
approaches, there's a silly sidebar story at the assisted living
center where Ruby works that throws the candy striper in jail on a
bogus "angel of mercy" murder rap (never properly cleared up).
Don't you just hate when that happens? God forbid Mona should get
a life, take the soccer-devoted girl to one of her school matches,
actually fess up to her daughter, and get her friend out of jail.
Hey someone has to have priorities. Alas, the two-faced conniver is
busy prancing about the runways in her bathing suit. Am I missing
something? What's to like here?
Certainly not the script by co-producer Jon
Bernstein. The press material mysteriously omits his bio, but he's
the hack responsible for the forgettable Ringmaster,
his only other feature credit. Maybe Sally Field saw that title as
his freshman effort and thought it was a circus picture.
The only cute thing in sight is Eisenberg,
the also-ran-cola spokeschild and now-illegitimate offspring.
She's grown out of this fiasco, one hopes. The soft-drink company
should be credited as a co-producer, as it blatantly plants abundant
product placements on screen for the "P" drink and its potato
chip subsidiary. The tot gets one of the better insipid lines, and
you'll find it in the trailer. When Mona, fitfully searching for a
phony cause, asks "Do you know any handicapped people?" To which
Vanessa quickly responds, "Only you." Download it, play it,
erase it. Don't spend the money taking your kids to see this at
the theater. They won't speak to you again. Especially after
seeing Mona and Ruby drive off in a car without buckling their seat
belts. What kind of example are these mothers setting?
Ask yourself, "Why suffer through nearly
two hours of such drudgery and over-produced dance numbers (I'm
Every Woman) for five minutes of redemptive swill that
manipulates the tear ducts?" The hackneyed, semi-sacrificial
ending, straight out of Mr.
Holland's Opus and In
& Out, allows Mona to have her cake and eat it too. Me?
I'm still gagging. Where's that barf bag?
Directed by:
Sally Field
Minnie Driver
Hallie Kate Eisenberg
Joey Lauren Adams
Leslie Stefanson
Bridgette L. Wilson
Kathleen Turner
Written by:
Jon Berstein
www.nitrateonline.com Copyright © 1996-2005 by Nitrate
Productions, Inc. All Rights Reserved.


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home > archive > 2001 > this article
Toward Rational
Exuberance: The Evolution of the Modern Stock Market
How things change yet stay the same
By Steven Martinovich
Like most failed investors I have too many books which promised they could help me turn my one penny into two pennies by playing in the stock market. As I used each book in turn I faithfully followed the strategies laid down only to turn two pennies into one. It turns out there may be a good reason why those books always failed me.
According to B. Mark Smith's Toward Rational Exuberance, the market is an ever-changing creature that routinely shrugs off old rules in favor of new ones. If you want to understand how the modern stock market works you have to understand that it is the product of an evolutionary process, and no market can be compared to one in the past and conversely, trends can't be extrapolated into the future. If that doesn't discourage you, Smith also believes that investors have to learn how the evolutionary process works before they can begin to understand how the stock market functions.
Toward Rational Exuberance isn't a mundane guide to picking stocks but rather it is a study of the modern stock market beginning in 1901, a time that Smith says major trends began to manifest themselves that would define what today's market has become. The turn of the previous century saw a New York Stock Exchange laughably primitive to today's but incredibly different from its beginnings in the 1790s when it served as a base for trading primarily in bonds.
Though the bloom has come off the today's stock market thanks to the dot com implosion, the market in 1901 was viewed with widespread suspicion. A lack of transparency and information and a belief by brokers that they should be allowed to operate free from the restraints of public and government opinion combined to give the institution the odor of a swamp and make it the province of the very rich. From there Smith weaves his way through a century of characters ranging from infamous early stock speculators to god of the moment Alan Greenspan. Along the way, a constant idea threads its way through his narrative. The stock market is becoming less risky to invest in and thanks to competition is becoming ever more efficient.
What the end result of these trends will be is a matter for debate. According to Smith, two schools of thought today dominate the study of the stock market: believers in the efficiency of the market -- a stock price reflects the sum total of knowledge about that particular company -- and behavoralists -- those who believe that investors are affected by the noise of rumor and uninformed guesses which causes volatile markets. Smith doesn't endorse either idea, a wise move considering all the methods of analysis that have been left along the side of the road over the past century.
Smith could have decided to concentrate on a narrow range of years to make his point but thankfully each decade rates a good luck. Not surprisingly though, the book seems to give the stock market crash of 1929 and the Great Depression the deepest and most colorful coverage. Although the argument that the depression wasn't caused by the market crash - stocks had been trending down for months before the collapse in October - is hardly new, Smith raises several points that are usually ignored to strengthen his case, points raised - rightly or wrongly - by experts today explaining the Internet implosion.
If Toward Rational Exuberance has a weakness is that Smith only gives a cursory glance at the effects of politics on the stock market. While he does chronicle specific incidents of intervention in the economy by presidents such as Franklin Delano Roosevelt and John F. Kennedy, how day-to-day political influences distort the functioning of the market is largely ignored.
Despite that flaw, and it is an important one, Smith's work is an impressive entry in the field if only because of its accessibility. Proving that writing about the dismal science doesn't have to be dismal, Toward Rational Exuberance is an enjoyable way to learn the history of the ongoing drama of the market and why the investing tips your parents gave you probably didn't work when they were using them, much less when you employed them.
Steven Martinovich is a freelance writer in Sudbury, Ontario.
Buy Toward Rational Exuberance: The Evolution of the Modern Stock
Market at Amazon.com for
only $20 (20% off)
Other related articles: (open in a new window)
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Hi Everyone!
I wonder how everybody's GCSE and A Level exams have been going! I only recently just finished my AS exams this week on Wednesday and that feeling is just so gooood! This will give me more time to do more blog posts and I will be starting today with my blog about summer plans.
I feel like there are different types of people
1) Those who want to do everything they possibly can within a certain time and put pressure on themselves to do it and not get bored just sitting around all the time.
2) Those people who feel like after their exams come to an end, they are entitled to pure relaxation!
Either of these types of people are okay to an extent as long as those in (1) aren't over working themselves and those in (2) aren't becoming completely unhealthy…
I believe I sway to the type (1) type. I literally think of idea after idea and think of every possible way to carry it out and then go over things 100 times over to ensure there are no flaws. At this point plans begin to change and the checking 100 times starts again which can be extremely time-consuming and tiring.
So, as I already mentioned I finished my exams this Wednesday and began simply making a list that same evening of all the things I plan to do between now and the end of the 6 week holidays. This means I have around a month in which I will be starting my A2 courses at 6th form as well as a further 6 weeks of holidays.
I won't be mentioning on here the many of things I plan to do as of yet but my 18th birthday will be soon coming up so that is definitely a part of the list!
Another idea I had been to start making Vlogs and in order for me to predict whether or not this will be successful, I would appreciate my viewers voting on whether it is something you would like to see and if there are any specific topics and questions that you would like me to Vlog/Blog about!
Please follow this link to vote!
The purpose of my post really, is to perhaps motivate some of you into doing as much as you possibly can within the coming months when you have free time! Many of you will be finishing your exams shortly and some of you may be well past that stage. My career is one of the top things I have thought about when considering plans for the summer. The following few months will most certainly give time for you to write a CV and get a job or arrange work experience, perhaps try a new short course. It is definitely a good thing to think outside the box and really push yourself as far as you can. Whatever you do now can definitely impact what point you're at this time in 10 years…
It is of course very important to give yourself space to see your friends and family and get enough retail therapy!
I hope you all enjoy your summer and I hope you do well in your exams.
Wish you all luck with any that you have left!
Samreece x