text:
August 27, 2007
As it appeared in Case Daily
President Snyder Welcomes All to New Academic Year
Dear Case Western Reserve Community:
On behalf of the university's senior leadership, I want to welcome all of you to the campus and to the start of the academic year. To those of you new to the university—whether students, faculty or staff—please accept my special welcome and my very best wishes for your success as a member of our community.
As I look forward from the perspective of the very beginnings of my presidency, I want all of you to know that I am energized by the many possibilities I see for everyone at Case Western Reserve University. The challenges and opportunities ahead provide a real excitement and immediacy to our work here on the campus, and we must be prepared to look for imaginative solutions and unconventional answers.
We pledge to improve the financial standing of the university. The fiscal health of the institution is the framework upon which we build the exciting programs and academic offerings that make the university such a desirable destination for students and faculty. Additionally, I will be working with Interim Provost Jerry Goldberg and a cross section of the university community to create a university strategic plan that will be ambitious, innovative and measurable.
The beginning of the academic year is a good time to honor the traditions and history that make Case Western Reserve University one of the nation's preeminent research institutions. We need to be acutely aware of our university's important heritage and proud reputation. At the same time, we need to look to the future and the work ahead. I ask each of you to join with me in pledging to bring our best efforts to the opportunities ahead. By doing so, we will ensure our future will be as exemplary as our past.
Once again, I offer my personal thanks to all of you for being committed members of the Case Western Reserve community.
Barbara R. Snyder

subset: commoncrawl


text:
Big Government Exposes Sinister Plot To Encourage Critical Thinking In The Classroom
Blog ››› ››› NED RESNIKOFF
Only a couple of weeks after professional fabulist Andrew Breitbart kicked off his campaign to "go after the teachers," things are getting silly.
Today, Kyle Olson -- head of something called the Education Action Group Foundation -- published a video on Big Government which he claimed exposed a group of socialist school teachers plotting how best to "subtly fill [young minds] with Marxist and radical ideas."
Here's one of the "radicals" in the video laying out their spooky brainwaishing plot:
But I do think that wherever you possibly can, part of it is actually just allowing for room for critical thought in the classroom and allowing for students to think for themselves, talk about issues wherever possible, to bring in history and you know, radicals from the past and fight for that kind of thing. And I think there is space to do that.
So in Olson's view, "allowing for room for critical thought in the classroom" and "allowing for students to think for themselves" is indoctrination.
Breitbart and his followers can claim that his anti-teacher campaign is all about battling indoctrination, but really it's about the opposite. No wonder Olson finds "allowing for room for critical thought" to be such a malevolent concept. Critical thought demands hearing out opposing views, and opposing views are one thing Big Government would apparently prefer to keep out of American classrooms.
So who's pro-indoctrinating children again? The socialist who's for "allowing for students to think for themselves [and] to talk about issues," or the conservative who seems to think being a socialist is an automatic disqualification for teaching any subject?


text:
February 25, 2011
Owen Duston Visiting Asst. Professor of Philosophy and Teacher Education Sam Rocha told Wabash students Thursday they should study and not celebrate history.
Rocha made his point using examples like Black History month and Dr. Martin Luther King. He suggested instead of making Dr. King a celebrity to revere, instead study the man's history and ideas
His entire Chapel Talk can be viewed here:


text:
In this course, we'll cover some more advanced topics that we didn't have time for in Human Anatomy and Physiology I. We'll start with basic histology—the study of the different tissues in the body. You'll learn about the structure and function of epithelial, connective, nervous, and muscular tissue. You'll come to understand the different sub-types of these tissues, where they're located, and the special jobs they perform.
From there, we'll move on to a discussion of the different senses. We'll study how your brain receives and processes information from your skin, joints, muscles, and special balance organs in your ears. Then we'll discuss the sensations of sight, sound, taste, and smell. You'll learn about the organs that receive these sensations and how the brain makes sense of them.
We'll also delve into the important topic of cellular metabolism—the chemical reactions that occur in cells. You'll find out about the major types of chemical reactions and see why food, oxygen, and water are essential for these chemical reactions to occur. And you'll learn about classes of chemicals called acids, bases, and salts, and their significance in the body.
Then we'll focus on the human life span. We'll start with a detailed explanation of the process of fertilization, proceed to a discussion of pregnancy and childbirth, and finally, talk about significant events that occur from infancy through old age. You'll also discover ways to slow down the aging process.
By the end of this course, you'll have an even greater appreciation of the complexity and wonder of the human body!
Holly Trimble earned a bachelor's degree in physical therapy from the University of Colorado, a master's degree in pediatric physical therapy from Boston University, and a master's degree in biology from the University of Nebraska at Kearney. She also completed an additional 15 credit hours in education at the doctoral level. After working as a physical therapist for many years, Holly transitioned into teaching. She taught math and science to sixth-graders for several years at a private school, and also worked as a private tutor for children with learning disabilities. She has lectured on health-related topics to all age groups, from school-age children to adults, and she now works as an adjunct professor, teaching college-level anatomy and physiology. She received an Adjunct Faculty Excellence Award from her college and is the author of the eBook, College Success Now! as well as several ed2go courses.
Complete the form below and click the Reset Password button. If
we find your password, we'll send password reset instructions to the e-mail address
we have on record for you.


text:
The potential costs and benefits of Medicare have a huge impact on retirement planning. For most folks, health-care costs are among the largest they will face in their retirement years. And, contrary to what many believe, Medicare is not free.
You do have to "pay to play." In fact, Medicare expenses can be substantial, particularly if you don't plan properly in your retirement budget. The more you know about the impact of Medicare on your plan, the more manageable those costs will be.
Medicare has many components and costs that need to be figured into the retirement-planning equation. There are three main parts to Medicare: Medicare Part A, which generally covers hospital care; Part B, covering doctor visits and outpatient services; and Part D, which covers most prescription medications. While Part A is prepaid by most of us through payroll taxes, Parts B and D are not. Instead, subscribers pay premiums priced on a sliding scale that is, in turn, based on income in retirement. (If you're wondering about Medicare Part C, click here.)
(Read more: Health insurance exchanges: CNBC Explains)
The smart thing to do is figure those Medicare premiums into your retirement planning. That way, there will be no surprises. Whether you plan for these health-care costs or not, you'll still have to pay for them. And then you may find yourself dipping into your nest egg more often than you planned, leaving you short on money to live on—a bitter, but preventable, pill to swallow that you can avoid with effective retirement planning.


text:
'Crime Trends Targeting
Andi Querry, a crime prevention specialist with the Newport Beach Police Department, will be about "Crime trends targeting seniors," during the February meeting of the Daughters of the American Revolution, which starts at 11 a.m. at Liberty Baptist Church, 1000 Bison St.
Geena Davis and Co.
Actress Geena Davis, California Secretary of State Debra Bowen, Rep. Linda Sanchez, state Senate Majority Leader Ellen Corbett, Orange County Sheriff Sandra Hutchens and Newport Beach Mayor Nancy Gardner will speak in support of the California Commission on the Status of Women at a reception in Newport Beach. A VIP reception is scheduled for 5:30 p.m., followed by a general reception at 6:30 p.m. The receptions will take place at the Newport Beach Fairmont Hotel, 4500 MacArthur Blvd. For more information, go to http://www.women.ca.gov.
'The New Hollywood'
The Newport Beach Public Library Foundation presents "The New Hollywood with Robert Kline." Kline, a producer, director and ex-studio head, will talk about this year's Oscar nominations. His presentation will include a feature on George Clooney. General admission tickets cost $20 (Foundation members pay $15). The program is from 7 to 8:30 p.m. in the Friends Room at the Newport Beach central Library, 1000 Avocado Ave. For tickets, go to http://www.nbplfoundation.org or call (949) 548-2411.
'The Borrowers'
South Coast Repertory Co.'s Theatre for Young Audiences presents "The Borrowers," an adaptation by Charles Way of Mary Norton's book series by the same name. The production features a blend of puppets and actors. Tickets go from $20 to $32. For showtimes and more information, go to http://www.scr.org or call (714) 708-5555.
'Elemeno Pea'
South Coast Repertory, 655 Town Center Drive, Costa Mesa, presents playwright Molly Smith Metzler's "Elemeno Pea." The play is a "comedy about class, family and the choices that shape who we are," according to a release. For showtimes and more information, visit http://www.scr.org.
'Pack of Lies'
Newport Theatre Arts Center presents "Pack of Lies," a play directed by Sharyn Case. The theater is at 2501 Cliff Drive, Newport Beach. For ticket and showtime information, go to http://www.ntaonline.com, or call (949) 631-0288.
Newport Harbor Republican Women Meeting
Writer Jamie Glazov will talk about "Honor Crimes Against Women: How the Left Controls the Culture and Narrative on this Issue" during the February meeting of the Newport Harbor Republican Women. The event is from 11:30 a.m. to 1:30 p.m. at the Pacific Club, 4110 MacArthur Blvd., Newport Beach. Admission is $45. For more information, call (949) 720-1726 or go to nhrw.org.
Grand Opening Party
Rebecca Taylor celebrates the opening of its store at Fashion Island with a party from 6 to 8 p.m. During those hours, shoppers can enjoy discounts of 10%. A portion of proceeds from sales during the evening will benefit the Junior League of Orange County, a local nonprofit.
MFA Show Opening
Second-year Master of Fine Arts students at UC Irvine's Claire Trevor School of the Arts will have an opening reception for their group show, from 6 to 9 p.m., in the University Art Gallery and the Room Gallery at UCI. The show will continue till March 9. For more information, go to http://www.ucigallery.com.
'Whither Japan'
The Newport Beach Sister City Assn. presents "Whither Japan," a lecture about Japan's social, demographic, economic and political future by Stephen M. Harner, a Newport Beach, Tokyo and Shanghai resident who now blogs about Japan. The free lecture begins at 7 p.m. in the Friends Room at the Newport Beach Central Library, 1000 Avocado Ave., Newport Beach.
Virtuoso Violinist in Concert
The Pacific Symphony presents a concert with Israeli violinist Vadim Gluzman, who will perform Tchaikovsky's "Violin Concerto" on a Stradivarius made in 1680. The concert, which starts at 8 p.m. at the Renée and Henry Segerstrom Concert Hall, 600 Town Center Drive in Costa Mesa, will feature the world premiere of composer Michael Daugherty's "The Gospel According to Sister Aimee," which will be performed by renowned organist Paul Jacobs. For more information, call (714) 755-5799 or go to http://www.PacificSymphony.org.
DJ Eddie Halliwell headlines Sutra, 1870 Harbor Blvd., Costa Mesa. The 21-and-older show starts at 9 p.m. For more information, call (949) 722-7103 or visit http://www.sutraoc.com.


text:
Sunday, July 22, 2007
Half Wheat Bread
Pondering what bread to bake next, I looked in the cupboards with my bread-making equipment and noticed bread pans. Hmm, I said to myself, I haven't made a plain loaf of bread for many months. I also said to myself, I haven't used this whole wheat flour for a while. (In fact, when I looked at the flour, I saw that it's "best if used before" date was sometime last year. I know how Rose feels about old flour, but I decided to use it one more time before I threw it away).
I looked at a bunch of recipes, but nothing quite struck my fancy. The whole wheat breads all looked too dense and hearty, and I was in the mood for something lighter. I finally decided to use Rose's basic white bread recipe and just substitute half whole wheat flour; hence the half wheat. Or it could be half white, I guess. (No, not half wit).
This bread came out very well, especially for being rushed into shape. We had to leave at 5:00, so I wanted the bread to be ready by 3:00. I started mixing the sponge around 9:30, but when I read the recipe carefully, I realized that if I used all the maximum rising times, the bread would not come out of the oven until 6:00. So I used the minimum rising times, and shaved some more time off. It didn't seem to matter one bit. I probably wouldn't have needed to throw the elderly flour away after all.
But the real star of this bread was the butter. You may have seen the article in the NYTimes about making your own butter. I cut it out, but didn't really intend to try it. I mean, how Little House on the Prairie is making your own butter? If you start that, soon you'll be weaving your own yarn, or putting a henhouse in your garage. But the lure of home-churned butter is too great to resist.
Well, off course, it's not home-churned. It's home KitchenAided with the whisk attachment. I have always loved to whip cream. It was my job as a child whenever we had dessert with whipped cream, which was never often enough. But my mother always cautioned me not to beat it for too long "or it will turn into butter." So I grew up with this idea that one millisecond too long, and your nice whipped cream would turn into a big chunk of butter. If my mother were still alive, I'd tell her not to worry: there is a long, long period of time before the whipped cream becomes butter. But that's all there is to it. Whip it long enough (like ten minutes) and suddenly, immediately after attaining a curdish consistency, it starts sploshing liquid onto the plastic wrap that the directions have helpfully told you to cover the bowl with, it does what it's supposed to do. The thick stuff is butter. The milky stuff is--you'll never guess--buttermilk.
I like my butter unsalted, but Jim doesn't, so, like the good wife that I am, I sprinkled a little sea salt into most of the butter.
If I had had more time, I might have shaped the butter into something cute. As it was, we barely had time to cut into the still warm bread, slather it with incredibly fresh and delicious butter, and eat three pieces each.
Then we had to leave to go to a party. It's a hard life, but someone has to do it.
10 comments:
- jini said...
wow! how lucky that you had just enough time slather that yummy butter on 6 pieces of bread so you and jim could eat them and BLAST out the door and arrive on time. :)
you are not a half wit......you are a true wit! with an outstanding sense of humor.
- Melinda said...
Yes, you are getting very show-offy in making your own butter! You'll be making your own mustard and ketchup next, Laura Ingels!
I must admit Rose has put me off using my wholewheat flour by saying it goes rancid very quickly. But I really can't taste a rancid taste. She must have hyper sensitive taste buds. I don't store it in the freezer either.
I gotta say, BBC, sometimes I read your blog and find we are thinking about the same stuff (actually, I think it's just that we both read the Wed and Sun NYT). Where did you get the cream for the butter? I wanted to make it too, but the nearest Whole Foods (where I'm thinking I could get either organic heavy cream, or just heavy cream without stabilizers) is about an hour away and I haven't gotten the ambition up to hitch up the wagon yet.
Oh! Have you tried making mozzarella yet (and then ricotta with the whey)? Easy as pie. Easier than pie. Made some last weekend from some local raw milk (no cream though), yummy and quick. Here's a link if you want the specifics http://www.pocketfarm.com/?cat=17.
My husband is threatening to get me a WWMID t-shirt
Once again, great blog
Chris in RI
Homemade bread AND homemade butter, it just does not get any better than that.
I checked out Jim's blog, WOW! I wish I could make bread and look out on such beautiful gardens.
- breadchick said...
WOW! That is all I can say (that and I can almost taste that butter on that bread). Now where is my Laure Ingells outfit...
- breadbasketcase said...
Thanks! I actually can be somewhat half-witted at times, but I'm glad you haven't picked up on it.
I hate ketchup and would never make it. I think I must be one of only two or three Americans who doesn't like ketchup. And I've never made jam either. You should try making butter yourself--you can probably buy better cream than we can here in the states.
I just got regular whipping cream from the nearest grocery store. If I'd planned ahead, I would have gone to the co-op, and bought some excellent cream from a local organic farm. I'm very excited by the make-your-own mozzarella idea! Far better than making ketchup.
Jim started the flower blog at my request, so I'd know what flowers bloomed at what time. Now that I have the record, I've found something else to get obsessive about. I want to have at least one new flower in bloom every day of the season, from mid-April to mid-September. I'm fine in the spring, but I need lots more late summer-early fall things.
You must find your Laura Ingalls Wilder outfit and then make butter yourself! You'll love it.
- jini said...
am i the only one to be in the dark about this flower blog by jim? would he be willing to weed my garden???
- breadbasketcase said...
You're not the only one who doesn't know about the flower blog--in fact, I'm surprised anyone knows about it because its whole purpose is just to record what flowers I have in my garden. It's at www.firstblooms2007.blogspot.com
And no, you can't have him as a weeder. He is already spoken for. And he is a very thorough weeder. Whereas I pull up some weeds, then see something that needs deadheading, then see something else I don't like the looks of, Jim stays with a given spot until it is 100% weed-free. I irritate him because I am so easily distracted.
- Chubbypanda said...
I actually want to put up a hen house once I have a large enough yard. Hooray! Organic eggies for me!
- breadbasketcase said...
Have you ever been around chickens? We had some once when I was a kid. My dad had the idea that we'd have fresh eggs and fresh roast chicken. All I remember is that the chickens were very mean and ran after me, trying to peck me. I also remember that my dad was never able to bring himself to kill the chickens. Eventually we gave them away. I hope that you get some good-tempered hens!


text:
About QIAGEN
Log in
Contact us
Quick Order
Top Products
New Products
Ordering Support
Next-Gen Sequencing
Lab Basics
Analytics Software
Protein & Cell Assays
RNAi & Transfection
Browse by Products
Custom Assays, Probes & Plates
LNA Oligonucleotides
Show All
Sample Technologies
Show All
End-Point PCR Enzymes & Kits
qPCR Arrays and Assays
qPCR Enzymes & Kits
Show All
Automated Solutions
Sample Disruption
PCR Instruments
Show All
Detection Solutions
Human Pathogens
Personalized Healthcare
TB Testing
Show All
Next-Gen Sequencing
GeneReader NGS System
QIAseq NGS Solutions
Molecular Diagnostics
Infectious Disease
Tuberculosis Management
Partnering for Precision Diagnostics
Transplantation Testing
Women's Health
Life Science Research
Automated Solutions
RNA Research
Liquid Biopsy Research
Research Applications
Cancer Research
Immuno-oncology Research
Neurodegenerative Disease Research
Drug Development
Environmental & Water Testing
Microbiology Research
Plant Research
Single Cell Analysis
DNASeq Data Analysis
RNASeq Data Analysis
Human ID & Forensics
Investigator Solutions
Human ID Applications
Human DNA Quantification
STR Technology
NGS in HID and Forensics
Validation and Training Support Services
Animal & Vet. Testing
Poultry Testing
Swine Testing
Ruminant Testing
Equine Testing
Automated Solutions
Food Safety Testing
Food-Borne Pathogen Detection
GMO DNA Detection
Ingredient Authentication
Genomic Services
Service Solutions
Custom Solutions
General Capabilities
World-Class Facilities
Custom Product & Packaging
Sample Technologies
Automated Technologies
Data Analysis Center
Pathway Central
Array Finder
GeneGlobe Lists
Knowledge Hub
Search Resources
All Resources
Kit Handbooks
Instrument User Manuals
Application/Protocol Sheets
Certificates of Analysis
Knowledge Area
Explore the RNA Universe
Cancer Research
Liquid Biopsy
Nucleic acid extraction
Reproducibility through automation
Sample Quality Control
HPV Testing
Microbiology & Microbiome
Single Cell Analysis
The GeneReader NGS System
GeneRead Sequencing (NGS)
High-Resolution Melting (HRM)
LNA (Locked Nucleic Acids)
QIAGEN Blogs
Plasmid Resource Center
QuantiFERON Technology
REPLI-g Amplification (WGA or WTA)
Investigator Forum 2017
Virtual Demos
Mol. Biol. Methods
Whole Genome Amplification
Next-Generation Sequencing
Animal Cell Culture
Find & Order
ProductFinder (all solutions)
Automated Solutions
HPV Testing
Human ID Testing
Personalized Healthcare
Prenatal Testing
Event Calendar
North America
Product Selection Guides
Genomic DNA Selection Wheel
RNA Selection Tools
DNA Cleanup Selector
Plasmid Prep Selection Guide
PCR Selection Guides
AllPrep Kits Guide
Innovations & Insights
Are We Ruled by Our Microbiome?
How Can We Fight an Ancient Disease?
How Can We Keep Animals Healthy?
What Happened to Richard III?
How Can We Beat Cancer?
Want to Save 275,000 Lives Each Year?
What's for Lunch?
Which Drug Works for You?
Android Apps
iOS Apps
Troubleshooting Guide
Quality & Safety Data
GHS Hazard Labeling
Certificates of Analysis
Protein Crystallization
Safety Data Sheets
Quality Assurance
Order Support
Contact Customer Care
Ordering Information
Technical Support
Contact by Web Form
Contact by Phone or Fax
About Us
What We Do
Who We Are
Insights Magazine
Global Presence
Social Hub
Investor Relations
At a Glance
Share Information
Financial Reports
Events & Presentations
Corporate Governance
Compliance & Ethics
IR Contacts
Press Releases
Press Resources
Photo Archive
Video Footage
Press Contact
Price Inquiries
Price Inquiries
Technical Inquiries
Global Contacts
Subscribe to eNews
Corporate Contacts
Where We Are
What We Offer
Collaborative Culture
Social Environment
Career Paths
Career Development & Training
Compensation & Benefits
Contact HR
Who We Are
Facts & Figures
Awards & Recognitions
Why QIAGEN
Our Mission, Vision, Strategy
Our Values
Molecular Biology Revolution
Outreach Programs
Meet Our People
What We Do
Our Products
Our Markets & Customers
Innovation at QIAGEN
The role of inflammation in cancer
Authors: Chunxiang Liu, PhD and Elana Ehrlich, PhD
Art Direction: Ken Mattiuz
Main Image Navi
Precancerous inflammation can cause increased genetic and epigenetic damage
Aberrant oncogenic signaling can induce inflammation
The inflammatory response in cancer tissues elicits tumor tissue remodeling and metastases
"Smoldering" inflammation can increase cancer risk by accumulating genetic and epigenetic damage
Aberrant oncogenic signaling can induce inflammation
Future questions
Back to top
Cancer-related inflammation can fall into one of two categories: 1. precancerous inflammation lesions and 2. Inflammation that is present in almost all cancer tissues including those that have no precancerous inflammation lesions. The connection between inflammation and cancer can be thought of as consisting of two pathways: an extrinsic mechanism, where a constant inflammatory state contributes to increased cancer risk (such as inflammatory bowel disease); and an intrinsic mechanism, where acquired genetic alterations (such as activation of oncogenes) trigger tumor development (see figure, Inflammation of external origin is responsible for increased cancer risk via induction of genetic and epigenetic aberrations in affected cells).
The former can increase the risk to cancer development, while the latter are necessary to maintain and promote cancer progression. The roles and the relationship between the two pathways in the cancer development process depend on their specific interactions between genetic/epigenetic factors and environmental factors. The accumulated evidence, obtained using in vivo and in vitro genetic disease models and the analysis of clinical patient samples by various methods including PCR analysis, strongly favors the theory that both precancerous inflammation and inflammation stemming from genetic alteration can cause cell transformation and promote tumor progression. There is strong evidence that inflammation contributes to the incidence of and mortality resulting from a number of tumor types. Examining this relationship via real-time PCR analysis of gene expression and epigenetic state in the inflammatory and tumor microenvironment will contribute to our understanding of cancer initiation and progression and will aid in the discovery of biomarkers for clinical use and drug development (1-3).
Back to top
Chronic inflammation conditions, caused by genetic mutations, autoimmune diseases, and exposure to environmental factors can increase the risk of cancer. Epidemiological studies have attributed up to 25% of cancer deaths worldwide to chronic inflammation (4). Chronic inflammation associated with microbial infections (Helicobacter pylori), autoimmune diseases (inflammatory bowel disease), inflammatory conditions of unknown origin (prostatitis) and smoking are well documented to increase the risk of certain cancers (5).
Inflammation is present in cancer tissues that arose without precancerous inflammation. The inflammatory state is necessary to maintain and promote cancer progression and accomplish the full malignant phenotype, such as tumor tissue remodeling, angiogenesis, metastasis and the suppression of the innate anticancer immune response (6). In these cancers, inflammation is elicited by genetic and/or epigenetic mutation that triggers cell transformation and maintains the autonomous proliferation of the transformed cells.
Tumor-infiltrating leucocytes as well as cytokine related signaling pathways are critical components in the development of the inflammatory tumor microenvironment. Understanding the roles of each type of cell and signaling pathway involved in cancer initiation and progression is critical to the discovery of biomarkers specifically targeting cancer inflammation (7-9).
Back to top
"Smoldering" inflammation can increase the cancer risk by accumulating genetic and epigenetic damage
Increased cancer risk is attributed to the observation that chronic inflammation can cause genetic damage via production of oxidizing compounds, such as reactive oxygen and nitrogen species. These products can induce the formation and accumulation of mutagenic, toxic, and/or genome-destabilizing DNA lesions (1, 10-15) . Inflammation related signaling has also been shown to suppress the activity of the DNA damage repair system (1). For example, neutrophils, the major source of reactive oxygen species, can also inhibit DNA base-excision repair (16, 17). IL-10, an important anti-inflammatory cytokine, can suppress the activity of the DNA damage response. In IL-10 knock out mice, a genetic mouse model of inflammatory bowel disease, the frequency of DNA mutations in colon tissue, in the absence of exogenous carcinogen, is 4-5 times higher than in wild type mice (18).
Epigenetic damage, such as aberrant DNA methylation, aberrant histone modification and miRNA expression is well recognized as a major driving force in cancer development and progression (19, 20). The presence of reactive oxygen species in the inflammatory state has been associated with epigenetic damage (21). Reactive oxygen species can induce aberrant DNA methylation via DNA damage. This is believed to be the mechanism of chemical or radiation associated aberrant DNA methylation.
Polycomb complex target genes (PcGs) play an important role in embryonic development and aging via epigenetic reprogramming. These genes are the major targets of aberrant DNA methylation and histone modification in cancer cells. In a mouse model of intestinal inflammation and cancer, not only is inflammation associated with increased global aberrant DNA methylation, but more than 70% of aberrantly methylated genes were PcGs (22).
Helicobacter pylori infection is a well characterized example of increased cancer risk in the setting of bacterial infection. Inflammation caused by bacterial infection has been shown to markedly increase cancer risk. This has been correlated with aberrant DNA methylation in gastric epithelial cells (23).
Back to top
Aberrant oncogenic signaling can induce inflammation
To obtain a malignant phenotype, the cell needs to acquire genetic or epigenetic mutations to trigger transformation. This malignant phenotype must then be maintained. The inflammatory response in cancer tissues play an important role in maintaining the phenotype by inducing tumor tissue remodeling, angiogenesis, and metastasis; all while suppressing the innate anticancer immune response (6). Such an inflammatory response can be elicited by activated oncogenic signaling pathways. This is well established in human papillary thyroid cancer. In human papillary thyroid carcinoma, activation of the RET oncogene by chromosome rearrangement is sufficient to trigger transformation of a thyrocyte to a carcinoma (24). The activated RET oncogene can also activate a program of inflammatory genes in affected thyrocytes. Activated genes include colony-stimulating factors (CSFs), interleukin 1β (IL-1β), cyclooxygenase 2 (COX2), CC-chemokine ligand 2 (CCL2) and CCL20, IL-8 or CXC-chemokine ligand 8 (CXCL8 CXC-chemokine receptor 4 (CXCR4), extracellular-matrix-degrading enzymes, and lymphocyte selectin (L-selectin) (see figure, RET oncogenic signaling pathway activation is a well-characterized example for the intrinsic origin of cancer inflammation). RET-activated inflammatory proteins were found in tumor biopsies. Interestingly, larger amounts of these inflammatory molecules were found in primary tumors from patients with lymph-node metastasis than in primary tumors without lymph-node metastasis. This observation suggests that the higher activity of the inflammatory pathway is associated with thyroid carcinoma metastasis. The specific role of these factors in the development of the cancer phenotype are not yet clear.
The Ras-Raf signaling pathway has been shown to cooperate with chronic inflammation to facilitate cell transformation. In a mouse model, both chronic pancreatitis and mutated K-ras are required to induce pancreatic intra-epithelial neoplasia and invasive ductal carcinoma. While aberrant Ras-Raf signaling can drive tumor-promoting inflammation to a certain extent, an extrinsic inflammatory condition such as pancreatitis is needed to drive carcinogenesis (25).
The NFκB signaling pathway is a key coordinator of innate immunity and inflammation. NFκB signaling plays crucial roles in both precancerous chronic inflammation as well as cancer induced inflammation. Frequently activated by cancer gene mutation, NFκB is an important regulator of tumor initiation and progression. Activation of this pathway induces expression of inflammatory cytokines, adhesion molecules, enzymes in the prostaglandin-synthesis pathway (such as COX2), inducible nitric oxide synthase (iNOS) angiogenic factors and anti-apoptotic genes (such as Bcl-2) (3).
Unchecked activation of immune associated signaling pathways has been associated with the development and maintenance of the tumor phenotype. The Ras-Raf signaling pathway is frequently mutated and aberrantly activated in many human cancers. Activation of this pathway induces the expression of tumor promoting chemokines and cytokines (25). Myc oncogene activation has been associated with the remodeling of the extracellular microenvironment, a process requiring cytokines, chemokines, and recruited mast cells. This process promotes tumor angiogenesis and metastasis (17). Tumor suppressor genes PTEN, p16, p53 (1, 26) and VHL have also been implicated in the induction of inflammatory mediators that may contribute to tumor progression (27).
Similar to NFκB, the STAT3 - TGFβ signaling pathway is involved in numerous oncogenic signaling pathways (28, 29). These transcription factors are constitutively activated in tumor cells and are involved in oncogenesis and inhibition of apoptosis. The activation of STAT3 in tumor cells has also been implicated in immune evasion via inhibition of dendritic cell maturation and the subsequent immune response.
Back to top
Future questions
Despite the exciting advances in the field of cancer inflammation research, many questions remain. The cross talk between the different signaling pathways involved in cancer-related inflammation is an area that remains unclear. This is not surprising based on the high heterogeneity of genetic and epigenetic alterations present in different cancers, differences in host genetic background as well as tissue specific inflammatory responses. Many challenges lie ahead: Are there aspects of cancer-related inflammation common to all malignancies? Are there unique inflammation biomarkers that can discriminate cancer related inflammation from non-cancer related inflammation? What is the relationship between the components and mediators of the cancer inflammatory response? How can cancer-related inflammatory pathways be targeted for drug development? Defining the roles of inflammatory mediators and the underlying signaling pathways will be critical to increasing the understanding of cancer initiation and progression. This will aid in the discovery of biomarkers for disease stratification, molecular diagnosis & prognosis, therapy selection and drug development.
Back to top
Hussain, SP, Hofseth LJ, and Harris CC, (2003) Radical causes of cancer. Nat. Rev. Cancer 3, 276-85.
Mantovani, A, Allavena P, Sica A, and Balkwill F, (2008) Cancer-related inflammation. Nature 454, 436-44.
Wu, Y, and Zhou BP, (2010) TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br. J. Cancer. 102, 639-44.
Balkwill, F., and A. Mantovani, (2001) Inflammation and cancer: back to Virchow? . Lancet. 357, 539-545.
Slattery, ML, Wolff RK, Herrick J, Caan BJ, and Samowitz W, (2009) Tumor markers and rectal cancer: support for an inflammation-related pathway. . Int J Cancer. 125, 1698-704.
Wang, F, Arun P, Friedman J, Chen Z, and Van Waes C, (2009) Current and potential inflammation targeted therapies in head and neck cancer. Curr Opin Pharmacol. 9, 389-95.
Chechlinska, M, M Kowalewska, and R Nowak, (2010) Systemic inflammation as a confounding factor in cancer biomarker discovery and validation. . Nat. Rev. Cancer. 10, 2-3.
Demaria, S, et al., (2010) Cancer and Inflammation: Promise for Biologic Therapy. J. Immunother. 33, 335-51.
Rao, SK, et al., (2010) Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. Biol Chem. 285, 32512-21.
Colotta, F, Allavena P, Sica A, Garlanda C, and Mantovani A, (2009) Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis. 30, 1073-81.
Cooke, MS, Evans MD, Dizdaroglu M, and Lunec J, (2003) Oxidative DNA damage: mechanisms, mutation, and disease. . FASEB J. 17, 1195-214.
Federico, A, Morgillo F, Tuccillo C, Ciardiello F, and Loguercio C, (2007) Chronic inflammation and oxidative stress in human carcinogenesis. . Int. J. Cancer. 121, 2381-6
Nishikawa, M., (2008) Reactive oxygen species in tumor metastasis. . Cancer Lett. 266, 53-9.
Goetz, ME, and Luch A., (2008) Reactive species: a cell damaging rout assisting to chemical carcinogens. . Cancer Lett. 266, 73-83.
Maynard, S, Schurman SH, Harboe C, de Souza-Pinto NC, and Bohr VA, (2009 ) Base excision repair of oxidative DNA damage and association with cancer and aging. . Carcinogenesis. 30, 2-10.
Gungor, N, R. W. L Godschalk, D. M Pachen, F. J. Van Schooten, and A. M. Knaapen, (2007) Activated neutrophils inhibit nucleotide excision repair in human pulmonary epithelial cells: role of myeloperoxidase. FASEB J. 21, 2359-2367.
Shchors, K, Shchors E, Rostker F, Lawlor ER, Brown-Swigart L, and Evan GI, (2006) The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta. Genes Dev 20, 2527-38.
Sato, Y, et al., (2006 ) IL-10 deficiency leads to somatic mutations in a model of IBD. Carcinogenesis. 27, 1068-73.
Jones, PA, and Baylin SB., (2007) The epigenomics of cancer. Cell 128, 683-92.
Feinberg, AP, (2008) Epigenetics at the epicenter of modern medicine. JAMA 299,
Franco, R, Schoneveld O, Georgakilas AG, and Panayiotidis MI, (2008) Oxidative stress, DNA methylation and carcinogenesis. Cancer Lett. 266, 6-11.
Hahn, MA, et al., (2008) Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. . Cancer Res. 68, 10280-9.
Niwa, T, et al., (2010) Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Cancer Res. 70, 1430-40.
Borrello, MG, et al., (2005) Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene. . Proc. Natl. Acad. Sci. 102, 14825-30.
Guerra, C, et al., (2007) Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell. 11, 291-302.
Blanco, D, et al., (2007) Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathway. Neoplasia. 9, 840-52.
Solinas, G, Germano G, Mantovani A, and Allavena P, (2009) Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol. 86, 1065-73.
Bierie, B., and H. L. Moses, (2006) TGF-β and cancer. . Cytokine Growth Factor Rev. 17, 29-40.
Yu, H, M Kortylewski, and D Pardoll, (2007) Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nature Rev. Immunol 7, 41-51.
Top products
Sort options
Sort alphabetically
Sort by relevance
RT2 Profiler PCR Arrays
For pathway-focused gene expression analysis using laboratory-verified assays
Show details
See products
Show all
Show less
Contact QIAGEN
Global contacts
Technical Service
Customer Care
QIAGEN Apps
Apps for your mobile devices!
See apps
Sample to Insight
Investor Relations
Press & Media
Privacy Policy
Trademarks & Disclaimers
Popular Products
Bosnia and Herzegovina
Central America and Caribbean
Costa Rica
Czech Republic
Faroe Islands
Hong Kong
New Zealand
Other Countries
Other South American Countries
Russian Federation
Saudi Arabia
South Africa
United Arab Emirates
United Kingdom
United States
Chinese (Simplified, PRC)
Japanese (Japan)
Korean (Korea)
Contact QIAGEN:
Contact Technical Service
Contact Customer Care
Sunshine Act
More Contacts
© QIAGEN 2013–18. All rights reserved


text:
Obama surrenders in Obamacare battle
Voluntarily seeks dismissal of appeal over health-care mandate
The Obama administration has surrendered in a key fight with a Christian publisher over the abortion pill mandate in Obamacare, asking a federal court to dismiss an appeal of a ruling that prevented application of the mandate.
The move was confirmed today by the Alliance Defending Freedom, which is representing Tyndale House Publishers.
Tyndale, of Carol Stream, Ill., went to court because it objects to providing abortifacients, as Obamacare requires of every health coverage plan.
Tyndale, the world's largest privately held Christian publisher of books, Bibles and digital media, won in a lower court, which ordered that the abortifacient requirement not be applied to the publishing company.
The Obama administration appealed the ruling, but the U.S. Court of Appeals for the District of Columbia has dismissed the appeal at the request of the famously pro-abortion Kathleen Sebelius, the secretary of the Department of Health and Human Services.
The brief order noted that the court panel granted a request from the Obama administration for the "voluntary dismissal" of an appeal of the lower court's ruling against the abortifacient requirement.
That, according to ADF, means the preliminary injunction issued by a district court in November of last year will stand while the case, Tyndale House Publishers v. Sebelius, moves forward.
ADF noted that "the administration's retreat marks the first total appellate victory on a preliminary injunction in any abortion pill mandate case."
Apparently, ADF said, Obama is nervous "about trying to defend its position that a Bible publisher is not religious enough for a religious exemption to the mandate."
"Bible publishers should be free to do business according to the book that they publish," said Senior Legal Counsel Matt Bowman. "The government dismissed its appeal because it knows how ridiculous it sounds arguing that a Bible publisher isn't religious enough to qualify as a religious employer. For the government to say that a Bible publisher isn't religious is outrageous, and now the Obama administration has had to retreat in court.
"We will continue to argue that the administration cannot disregard the Constitution's protection of religious freedom for all family business owners and must offer a comprehensive exemption to the mandate," Bowman added.
The Obama administration previously argued before the court that the Bible publisher must be forced to violate its faith and beliefs to provide abortifacients to employees.
ADF said Obama's abortion pill mandate forces employers, regardless of their religious or moral convictions, to provide insurance coverage for abortion-inducing drugs, sterilization and contraception under threat of heavy penalties.
ADF is working on a number of additional lawsuits over the same issue, as are a number of other legal organizations.
WND reported a few months ago that the Obama campaign to demand the abortifacients was flopping in the courts.
At that point, the Obama administration had suffered 10 losses and only four victories in court fighting for the Obamacare abortion-pill mandate. Since then, there have been several other losses for Obama.
At that point, Bowman explained: "Washington politicians can't confine our faith to the four walls of our churches alone. Honoring God is important every day, in all areas of life, including in our work. The Obama administration's attacks on faith and business prove that it doesn't respect either one."
At the lower court level in the Tyndale case, U.S. District Judge Reggie B. Walton wrote: "The beliefs of Tyndale and its owners are indistinguishable. Christian principles, prayer and activities are pervasive at Tyndale, and the company's ownership structure is designed to ensure that it never strays from its faith-oriented mission. The court has no reason to doubt, moreover, that Tyndale's religious objection to providing insurance coverage for certain contraceptives reflects the beliefs of Tyndale's owners. Nor is there any dispute that Tyndale's primary owner, the Foundation, can 'exercise religion' in its own right, given that it is a non-profit religious organization."
ADF has created a video explaining its battle against the Obamacare abortion-pill mandate:


text:
The Oscars vs. GoDaddy
from the ah-loopholes deptThe Motion Picture Academy is somewhat infamous for its over-aggressive IP claims around the "Oscar" awards. It's even sued a blog that was helping to promote the event. Apparently, just suing one website wasn't enough, so back in May it sued domain registrar GoDaddy for allowing a bunch of domains to be registered.
Now, in a reasonable world, where liability is properly applied, GoDaddy would never be liable for actions of its users. But, unfortunately, one of the very few areas that DMCA and Section 230 safeharbors do not cover is trademark law. So, the Academy may actually be able to get away with blaming GoDaddy for not magically blocking anyone from registering any domain that might, possibly, maybe be about the Oscar Awards:
Suing under the Anticybersquatting Consumer Protection Act, the Academy disputes more than a 100 domain names, including 2011oscars.com, academyawardz.com, jaylenososcars.com, betacademyawards.com, oscarsunplugged.com, oscarshotels.com, oscarstravel.com, oscarsliveblogging.com ... etc. Damages could total as much as $10 million.On top of the basics of blaming GoDaddy for allowing such domains to be registered, the Academy seems to directly be taking issue with the fact that GoDaddy has a system for letting domain holders "park" those domains and make money from ads. The Academy tries to spin this as GoDaddy purposely "profiting" off of its intellectual property, but that's ridiculous. GoDaddy is just offering a general domain parking ad system. It's making money off of any parked domains. It has nothing to do with their intellectual property. And, frankly, if these domains were really so valuable to the Academy, why didn't they register them in the first place?
To make the whole thing even more ridiculous, the Academy claims that a GoDaddy patent application shows that it knows that it needs to filter out ads on certain types of domains. But just because you develop a system to do so, it doesn't mean you are legally required to abide by it.
The whole thing is, frankly, absurd. If the Academy has a problem with certain domains, it should go after those who actually registered them. Not the registrar. If this lawsuit actually gets anywhere, it could create a real chill for registrars, who will then feel the need to review and block certain registrations, even if they would be perfectly legal.
Filed Under: oscars, registration, third party liability, trademark
Companies: godaddy, motion picture academy


text:
Nobel Prize winners urge "Greens" to vote red
OTTAWA – Three senior Canadian members of the 2007 Nobel Prize-winning Intergovernmental Panel on Climate Change are publicly urging those who really care about the environment to vote Liberal.
"We face a critical moment," Dr. Andrew Weaver said in a news release.
Dr. Weaver, Dr. William Peltier and Dr. John Stone are urging potential Green Party voters to vote Liberal in order to stop the Harper government from winning.
"(Elizabeth) May and the Greens alone can help make the difference between the Harper majority that the climate scientists fear and a Liberal minority under which great progress can be made to fight climate change," said Dr. Weaver. (News Release, October 11, 2008)
Dr. Weaver told the Ottawa Citizen that a vote for the Green Party "is not a green vote.
"A green vote is for a Liberal government and Stéphane Dion. There is no other candidate you can vote for," he said. (Ottawa Citizen, October 12, 2008)
"Great progress", under the Liberal Plan. Another set of voices, outside of the partisan arena, that supports the Liberal argument. Their only self-interest is the state of our environment, nothing more, nothing less, the words should be heeded.


text:
Thomas Merton's Bridges to Contemplative Living
Feb. 19, March 5,12,19 Patricia Novak, OSF, will facilitate the Lent Series – Receiving the Gift of God's Mercy. Focus will be on a journey toward personal spiritual transformation and a more contemplative and peace-filled life. Each series offers an introduction to Thomas Merton and contemplative living through prayers, readings from Merton and other spiritual masters as well as questions for small group dialogue. Each series is four sessions. Call to register.
- When:
- 10 a.m.
- Where:
- 1016 N. Superior St.
- Cost:
- uggested donation $35 per series/includes the book
- Phone:
- (509) 483-6495
- Email:
- firstname.lastname@example.com
- Website:
- http://www.sjfconline.org/thomas_merton's_bridges_of_contemplative_living_at_the_franciscan_place.html
- More like this:
- Church, Lecture/Seminar


text:
Nevada used to be atomic blast central, so it's fitting that students at the University of Nevada at Las Vegas paid tribute to the weirdness of atomic-bomb art and propaganda with a new exhibition, "Cloud 9."
According to the UNLV student paper, the Rebel Yell, the UNLV Art Department collaborated with the Atomic Testing Museum to put together a weird nuke-themed exhibit:
"In the 1950s, everyone wanted to advertise with the mushroom cloud or the atomic symbol," said Angela Ameling, ATM director of education. "So there is quite a bit of that pop culture that we have in the museum. So the students took that portion of history and really ran with it."
Miss Atomic Bomb U.S.A. by Brynn Lee Gardano. Photo by Bryant Nguyen.
Operation Cupcake by (left to right) Lindsay Raybourne, Gina Scalice, Samantha Leavitt and Jennifer Coots. Photo by Bryant Nguyen.
Santuary by Ben Stoner and Katie Ferris. Photo by Bryant Nguyen.


text:
Great books of the western world
Mortimer J. Adler
Encyclopaedia Britannica, 1993 - Literary Collections
From inside the book
45 pages matching soldier in this book
Where's the rest of this book?
Results 1-3 of 45
What people are saying - Write a review
We haven't found any reviews in the usual places.
To the Lighthouse i
The Prussian Officer
The Waste Land
6 other sections not shown
Other editions - View all
Common terms and phrases
Animal Farm animals asked Beasts of England beautiful brant captain chair chaplain Charles Tansley Christine coming D. H. LAWRENCE Daisy damned dark dead death door Eliot's note everything eyes Ezra face farm father feel felt Gatsby Gatsby's give gone Gregor hand happened hazel head hear heard husband Kattrin knew laugh lavinia light Lighthouse Lily Briscoe listen live looked Macomber mannon married mind Minta morning mother courage moved Napoleon never night once orin peter Prue Ramsay remember round Samsa seemed seth silence sister sitting smile Snowball soldier Squealer standing stares stood stop strange suddenly Swiss Cheese T. S. Eliot talk tell There's things thought Tiresias told took turned Vinnie voice waiting walked watch wife William Bankes Wilson window Wolfsheim woman words young


text: Magnetics modules for LAN applications 1000 Base-T magnetics module Ordering code: B78476A8253A003 Date: October 2008 © EPCOS AG 2008. Reproduction, publication and dissemination of this publication, enclosures hereto and the information contained therein without EPCOS' prior express consent is prohibited. 1000 Base-T magnetics module B78476A8253A003 Single port, power over ethernet Features Ferrite toroid, case and potting (UL 94 V-0) Compliant with IPC/JEDEC J-STD-020C Compliant with IEEE 802.3af MSL level 2 Optimized for full duplex applications RoHS-compatible Marking EPCOS, middle block of ordering code, date code Delivery mode and packing unit 32-mm blister tape, 330-mm ∅ reel (cardboard packaging) Packing unit: 350 pcs./reel Dimensional drawing Layout recommendation Units: mm [inch] Values without tolerances are nominal values for reference. Please read Cautions and warnings and Important notes at the end of this document. Page 2 of 5 1000 Base-T magnetics module B78476A8253A003 Single port, power over ethernet Pinning Characteristics and ordering code (electrical specifications at 25 °C) Ordering code B78476A8253A003 Turns ratio (primary : secondary) 1CT : 1CT ±3% Inductance L 350 µH min. 100 kHz, 100 mV, 8 mA DC bias Voltage test Vtest 1500 V AC 1.1 dB max. 1.0 dB max. 2.0 dB max. 18 dB min. 16 dB min. 12 dB min. 10 dB min. 43 dB min. 37 dB min. 33 dB min. 33 dB min. 33 dB min. 33 dB min. 50 Hz, 1 min 0.1 MHz 100 MHz 125 MHz 1 MHz ... 40 MHz 50 MHz 60 MHz ... 80 MHz 100 MHz 30 MHz 60 MHz 100 MHz 30 MHz 60 MHz 100 MHz Insertion loss Return loss Crosstalk Differential to common-mode rejection (DCMR) Operating temperature range 0 °C ... +70 °C Weight Approx. 1.8 g Please read Cautions and warnings and Important notes at the end of this document. Page 3 of 5 1000 Base-T magnetics module B78476A8253A003 Single port, power over ethernet Cautions and warnings For soldering conditions please refer to JEDEC J-STD-020C. If the components are to be washed varnished it is necessary to check whether the washing varnish agent that is used has a negative effect on the wire insulation, any plastics that are used, or on glued joints. In particular, it is possible for washing varnish agent residues to have a negative effect in the long-term on wire insulation. The following points must be observed if the components are potted in customer applications: – Many potting materials shrink as they harden. They therefore exert a pressure on the plastic housing or core. This pressure can have a deleterious effect on electrical properties, and in extreme cases can damage the core or plastic housing mechanically. – It is necessary to check whether the potting material used attacks or destroys the wire insulation, plastics or glue. – The effect of the potting material can change the high-frequency behaviour of the components. Ferrites are sensitive to direct impact. This can cause the core material to flake, or lead to breakage of the core. Even for customer-specific products, conclusive validation of the component in the circuit can only be carried out by the customer. Please read Cautions and warnings and Important notes at the end of this document. Page 4 of 5 Important notes The following applies to all products named in this publication: 1. Some parts of this publication contain statements about the suitability of our products for certain areas of application. These statements are based on our knowledge of typical requirements that are often placed on our products in the areas of application concerned. We nevertheless expressly point out that such statements cannot be regarded as binding statements about the suitability of our products for a particular customer application. As a rule, EPCOS is either unfamiliar with individual customer applications or less familiar with them than the customers themselves. For these reasons, it is always ultimately incumbent on the customer to check and decide whether an EPCOS product with the properties described in the product specification is suitable for use in a particular customer application. 2. We also point out that in individual cases, a malfunction of electronic components or failure before the end of their usual service life cannot be completely ruled out in the current state of the art, even if they are operated as specified. In customer applications requiring a very high level of operational safety and especially in customer applications in which the malfunction or failure of an electronic component could endanger human life or health (e.g. in accident prevention or lifesaving systems), it must therefore be ensured by means of suitable design of the customer application or other action taken by the customer (e.g. installation of protective circuitry or redundancy) that no injury or damage is sustained by third parties in the event of malfunction or failure of an electronic component. 3. The warnings, cautions and product-specific notes must be observed. 4. In order to satisfy certain technical requirements, some of the products described in this publication may contain substances subject to restrictions in certain jurisdictions (e.g. because they are classed as hazardous). Useful information on this will be found in our Material Data Sheets on the Internet (www.epcos.com/material). Should you have any more detailed questions, please contact our sales offices. 5. We constantly strive to improve our products. Consequently, the products described in this publication may change from time to time. The same is true of the corresponding product specifications. Please check therefore to what extent product descriptions and specifications contained in this publication are still applicable before or when you place an order. We also reserve the right to discontinue production and delivery of products. Consequently, we cannot guarantee that all products named in this publication will always be available. The aforementioned does not apply in the case of individual agreements deviating from the foregoing for customer-specific products. 6. Unless otherwise agreed in individual contracts, all orders are subject to the current version of the "General Terms of Delivery for Products and Services in the Electrical Industry" published by the German Electrical and Electronics Industry Association (ZVEI). 7. The trade names EPCOS, BAOKE, Alu-X, CeraDiode, CSSP, CTVS, DSSP, MiniBlue, MKK, MLSC, MotorCap, PCC, PhaseCap, PhaseMod, SIFERRIT, SIFI, SIKOREL, SilverCap, SIMDAD, SIMID, SineFormer, SIOV, SIP5D, SIP5K, ThermoFuse, WindCap are trademarks registered or pending in Europe and in other countries. Further information will be found on the Internet at www.epcos.com/trademarks. Page 5 of 5


text:
I learned that a long walk and calm conversation are an incredible combination if you want to build a bridge.
Local Area
Express Check-In Available
Late Check Out Available
Minimum Check-In Age: 21
Daily Valet-Parking Fee
Wheelchair Available
Service animals are allowed
Learn more about the IHG Green Engage™ system
The award-winning Crowne Plaza® Detroit Downtown Riverfront Hotel stands out in downtown Detroit's business district, with its location neighboring the convention center near the riverfront. Located just off M-10 Lodge Freeway and within walking distance of Cobo Center, this Detroit hotel won IHG's Designer of the Year .
Eighteen meeting rooms, including a 12,000-sq-ft ballroom, offer meeting space with audio-visual capabilities and catering services for a variety of special events. A popular worldwide business draw, this downtown Detroit hotel is near the GM® world headquarters as well as Quicken Loans & Rock Financial Holdings® and PricewaterhouseCoopers® and DMC Medical .
Leisure guests find excitement at nearby popular sporting venues, which are home to the Detroit Lions-Ford Field, Detroit Red Wings and the Detroit Pistons-Little Caesar's Arena, and Detroit Tigers-Comerica Park. Historic Hart Plaza, Campus Martius, and the Riverwalk short walk, and must-see attractions for Motor City visitors. Don't forget the famous Greektown with a plethora of dining and entertainment options, including Greeektown Casino.
This Green Engage® city center hotel in downtown Detroit , and offers easy access to the Detroit "People Mover" transportation system. Experience rejuvenated city life on your next business trip or vacation at Crowne Plaza® Detroit Downtown Riverfront.


text:
Advanced Search
Portfolios | News
Blackboard Learn has added professional profiles for students in an effort to help connect them with job and internship opportunities.
The Enhanced Cloud Profile allows students to share information such as skills, competencies, degree plans and academic achievements with potential employers, instructors or fellow students. Privacy tools allow students to control "every aspect of their data," according to a news release.
"The profile can highlight the same things your resume would, but it tells a more compelling story," said Davante Lewis, University of Louisiana System student board member and student at McNeese State University, in a prepared statement. "It's a way you can market yourself beyond the typical 'what did you graduate in' and 'what jobs did you have.' This student profile is designed to show what students are capable of. It makes a huge difference in positioning yourself for a successful career."
Students can also link to their MyEdu account.
"The traditional resume is on its way out and online tools that work for mid-career professionals don't effectively show a college student's skills and accomplishments or truly distinguish their talents," said Jay Bhatt, CEO of Blackboard, in a prepared statement. "It just makes sense to leverage the environment students are in every day to house their educational information, to also showcase their skills and connect them to job opportunities."
The company has also announced a redesign of Portfolios. "While the Enhanced Cloud Profile allows for a high-level view of the educational identity of a student, Portfolios allows for a more in-depth look at specific project work and course assignments. Together, the features enhance the ability for students to illustrate their competencies and achievements through Blackboard Learn."
About the Author
Joshua Bolkan is contributing editor for Campus Technology, THE Journal and STEAM Universe. He can be reached at email@example.com.
View More Webcasts
View More Whitepapers
Sign up for our newsletter.
I agree to this site's Privacy Policy.


text: Job Discussion Forums :: View topic - Linguarama in France (and Europe) Get TEFL Certified & Start Your Adventure Today! Job Discussion Forums"The Internet's Meeting Place for ESL/EFL Students and Teachers from Around the World!" FAQ Search Memberlist Usergroups Register Profile Log in to check your private messages Log in Linguarama in France (and Europe) Job Discussion Forums Forum Index -> France View previous topic :: View next topic Author Message paulironmongerJoined: 20 Feb 2006Posts: 2 Posted: Tue Feb 28, 2006 7:35 pm Post subject: Linguarama in France (and Europe) Can anyone tell me about Linguarama? I mean, is it a good company to work for? I am considering applying for a post in Lyon, France. What is the money like? Is it good enough to live fairly comfortably in France? Actually, the same question goes to any Linguarama school in all the countries they operate. Any info would be much appreciated folks. Paul. Back to top Display posts from previous: All Posts1 Day7 Days2 Weeks1 Month3 Months6 Months1 Year Oldest FirstNewest First Job Discussion Forums Forum Index -> France All times are GMT Page 1 of 1 Jump to: Select a forum Where to Begin----------------General DiscussionNewbie ForumCurrent Events ForumTechnology ForumOnline Teaching Forum Africa Forums----------------General Africa Forum Asia Forums----------------CambodiaChina (Job-related Posts Only)China (Off-Topic)Hong KongIndiaIndonesiaJapanMalaysiaPhilippinesSingaporeTaiwanThailandGeneral Asia ForumVietnam Caribbean Forums----------------General Caribbean Forum Europe Forums----------------Czech RepublicFranceGermanyGreeceItalyMacedonia and the BalkansPolandRomaniaRussia & C.I.S.SpainTurkeyUkraineUnited KingdomGeneral Europe Forum Latin America Forums----------------ArgentinaBrazilChileColombiaCosta RicaMexicoMexico (off-topic)PeruGeneral Latin America Forum The Middle East Forums----------------BahrainEgyptIsraelKuwaitOmanQatarSaudi ArabiaUnited Arab EmiratesGeneral Middle East Forum North America Forums----------------General North America Forum Oceania----------------Australia/New Zealand You cannot post new topics in this forumYou cannot reply to topics in this forumYou cannot edit your posts in this forumYou cannot delete your posts in this forumYou cannot vote in polls in this forum This page is maintained by the one and only Dave Sperling. Contact Dave's ESL Cafe Copyright © 2018 Dave Sperling. All Rights Reserved. Powered by phpBB © 2001, 2002 phpBB Group Teaching Jobs in China


text:
rosienutrition needed a new logo design and created a contest on 99designs.
A winner was selected from 81 designs submitted by 25 freelance designers.
Ahara Nutrition
I am a nutritionist offering nutrition consultations and advice to clients on a wide range of health topics, such as weight loss, reducing blood pressure, improving energy, fertility and pregnancy, diet etc.
The company is professional and slick, offering high quality advice to professionals. The brand is aspirational; to evoke a sense that you can achieve anything. I want the logo to be clean, simple and and aspirational.
Wide target market but predominantly city / working professionals. I base myself in Devon, by the sea and work in a couple of small local towns but also spend half my week in London, working in the heart of the city where the majority of my clients are.
I am targeting people who want to be in the best of health and need advice on how to get there and for those who are in need for nutritional advice for a variety of health concerns. For many this is weight loss but for others is could be reducing blood pressure, heart disease, digestive problems, anxiety, stress, burn out etc.
Clients generally have a good level of disposable income as they will be paying privately for consultations. Well educated individuals who understand that nutrition is key to health.
I would like the logo to be: slick, simple, professional, elegant, clean,
Would like a professional logo that oozes style, professionalism and health.
Other words to sum up brand: Simple, clean, modern, professional, aspirational, vibrant, energetic, colourful, life giving.
The logo will appear on business cards, stationary, and website, and thus should be legible in various sizes. The logo should be legible in color or black and white.
Other than that please feel free to be creative.
Find out how a design contest works or learn more about our logo design services.


text:
Golf Media needed a new logo design and created a contest on 99designs.
A winner was selected from 105 designs submitted by 14 freelance designers.
Pocket Greenskeeper
We are a golf media and marketing firm specializing in golf products and services. This product is an inexpensive divot repair tool, which will be marketed as a corporate promotional product (companies will order this product with their logo on it for branding reach to golfers). More information about the product at: http://www.PocketGreenskeeper.com
Our target audience for this product will be golf industry principles as well as corporate promotional products buyers.
We would like the logo to be of a rich text nature, comprising the words "POCKET" and "GREENSKEEPER", and include a 'golf' green along with another complementary color (yellow, perhaps or another light color). Emphasis on the word "Greenskeeper". The word "Pocket" could be angled or floated above or above-left of the word Greenskeeper. Any golf-related image will be considered for enhancement (golf flag, golf ball, putting green, etc.) provided it is muted and does not overpower or interfere with the actual brand name logo. For more information about the product:
Find out how a design contest works or learn more about our logo design services.


text: You'll also find richness and refinement to fulfill your every dream: immaculate varnished teak, incredibly crafted furnishings, and an amazing attention to detail throughout. Beneath it all is the same semi-displacement hull design that made this boat a legend for its stability and fuel economy. If "practical luxury" sounds like a contradiction in terms, you haven't been aboard the 52EU.


text:
Some of the most striking green buildings we've seen come in the simplest packages, and this is definitely true of Judith Benzer Architektur's gorgeous summer home in Austria. Modeled after the Kellerstöckel (wine houses) typical of Austria's Southern Burgenland region and designed to enhance its surrounding environment, the raw, simple house has a ferroconcrete cellar where wine is kept and produced, while the ground and first levels are built entirely out of wood.
The cubed construction features copper corner plates that create stark edges against the verdant Austrian landscape, and Judith Benzer deliberately left the wood, steel and concrete materials unfinished and untreated so that it maintains a very natural appearance.
During the winter, when the home is not inhabited, larch shutters fold flat so that they are flush with the home's facade, not only protecting the home but also ensuring that it remains as unobtrusive as possible. These same shutters mitigate solar-gain during summers as they fold out as awnings on the side of the home. The minimalist interior is so clean and so full of light, and thoughtfully-placed windows provide excellent views of the bucolic outdoors.
Via Architizer


text:
Cabazon, CA
Sponsored Topics
Cabazon is a census-designated place (CDP) in Riverside County, California, United States. The population was 2,535 at the 2010 census, up from 2,229 at the 2000 census.
Cabazon was incorporated as a city in 1955. In 1972, after years of scandal, political instability, and stalled growth, the citizens of Cabazon voted to disincorporate the city. Cabazon then became the first community in California to give up cityhood in some 40 years. Interest in re-incorporating the area has been reported in the 2000s.
The 2010 United States Census reported that Cabazon had a population of 2,535. The population density was 518.0 people per square mile (200.0/km²). The racial makeup of Cabazon was 1,751 (69.1%) White, 135 (5.3%) African American, 90 (3.6%) Native American, 38 (1.5%) Asian, 14 (0.6%) Pacific Islander, 358 (14.1%) from other races, and 149 (5.9%) from two or more races. Hispanic or Latino of any race were 1,135 persons (44.8%).


text:
Montgomery, Ala. – The Tennessee State volleyball team won its second consecutive match with a 3-1 win (20-25, 25-17, 25-16, 25-14) over Southeastern Louisiana. The Tigers then followed up their win with another 3-1 victory (22-25, 25-15, 25-17, 26-24) against Stetson.
The wins gave the Tigers a 3-1 record in the ISTAP Invitational.
In the first match, TSU was led by junior setter Erika Moss, who notched a season-high 49 assists. Offensively, sophomore outside hitter Naomi Wells paced the Tigers with 22 kills while sophomores Serryce Butler and Rachel Ambroch chipped in with 14 and 13 kills, respectively.
Wells also added 11 digs, but senior libero Britani Hathorn led Big Blue with 17.
For Southeastern Louisiana, Beck Bekelja had 25 assists of the team's 27 assists. Courtney Donald was the only Lady Lion with double-digit kills with 10, but she also led the team with three errors.
The first set started slowly for TSU as Southeastern Louisiana jumped out to a 5-2 lead. Head coach Kathy Rouhlac called a timeout, and her team responded by pulling within one at 8-7. The team's traded blows until a series of service errors late in the set opened the door for Southeastern Louisiana.
Neither team was able to gain ground early in set two and the teams were tied at three. Then, a handful of errors from Southeastern Louisiana allowed TSU to pull away 9-6. From that point, the TSU hitters racked up kills and the Tigers ended the set on a 16-11 run.
With the match tied at one set apiece, Southeastern Louisiana showed some fight early in the set and neither team seemed to have the advantage. However, with the Tigers up 8-6, a pair of Lady Lion errors ignited a fire under TSU. The team rolled to a 25-16 set victory thanks to an 8-4 run.
With the match on the line, TSU made sure to finish off the Lady Lions in the fourth set, and did so in dominating fashion. The Tigers leapt out to an early 10-5 lead with four different players scoring kills. The Tigers didn't look back, and they proceeded to go on a 8-4 run with Moss setting up Wells and Butler with two kills apiece. The Tigers ended the match on a 5-2 run and Butler recorded the match-clenching kill.
In match two, Moss had 38 assists, Wells and Ambroch again notched double-digit kills and three players recorded ten or more digs.
Stetson had a pair of players with double-digit assists while two others had ten-plus kills.
Neither team was able to pull away in the first set until the score was tied at eight. A TSU service error sparked a 17-15 run from Stetson to close out the set.
However, TSU rebounded in set two with an 11-7 run to start the set. A timeout from Stetson didn't help the Hatters and TSU added to its lead via kills from three different players. A 6-2 TSU run gave the Tigers the equalizer and Moss got a rare kill to end the set.
The Tigers won the first two points of set three and never relinquished the lead. An 8-5 run highlighted by a pair of kills from Ambroch gave the Tigers a 2-1 set advantage.
The final set turned out to be a 26-24 thriller. TSU needed that extra point, but fended off a hard-fought Stetson run to seal the match.
The Tigers will return to action on the road in Portland, Ore. on Aug. 31 for the Nike Portland Invitational.
Follow TSU Athletics on Facebook.com/TSUTigers and Twitter @TSU_Tigers.


text:
Oracle Senior Member of Technical Staff in Charlotte, North Carolina
Design, develop, troubleshoot and debug software programs for databases, applications, tools, networks etc.
As a member of the software engineering division, you will assist in defining and developing software for tasks associated with the developing, debugging or designing of software applications or operating systems. Provide technical leadership to other software developers. Specify, design and implement modest changes to existing software architecture to meet changing needs.
Duties and tasks are varied and complex needing independent judgment. Fully competent in own area of expertise. May have project lead role and or supervise lower level personnel. BS or MS degree or equivalent experience relevant to functional area. 4 years of software engineering or related experience.
Oracle is an Equal Employment Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability and protected veterans status or any other characteristic protected by law.
Description:-?xml:namespace prefix = "o" /->
You will design, develop and implement tools and techniques that will impact Oracle s technologies. You will work alongside leading researchers, and develop solutions to solve complex issues in a variety of domains, including machine learning, network security, internet of things, data mining, data analytics, optimizations, distributed systems and scalability.
Preferred Qualifications
MS or PhD in Computer Science/Computer Engineering, focused on software design and development
Expertise in one or more areas - Machine learning,network security, internet of things, data mining, data analytics, optimizations, distributed systems and scalability
Strong problem solving, coding and optimization skills - C/C , Java, Python
Experience in UNIX/Linux environment
Strong verbal and written skills and the ability to articulate the technical underpinnings of a solution
Job: *Product Development
Organization: *Oracle
Title: Senior Member of Technical Staff
Location: United States
Requisition ID: 19000BMC


text:
Photos and captions by Dan Milner
Svalbard is one of the most remote places on earth. It's located north of mainland Europe, midway between mainland Norway and the North Pole. There's more polar bears than humans that live there. So when Jeremy Jones, and Terje Haakonsen decided to take a trip there, we just had to document it.
Check out the full story in our November issue out now!


text:
Introducing Beach Glass Soap Bath Products
Karen Buzenius grew up on Lake Michigan, in St. Joseph, and has collected beach glass for as long as she can remember. Now, she has channeled that passion into making a soap that has been tinted and shaped to celebrate this beautiful treasure of nature. With hues of citron, white, and aqua to resemble the natural beauty of beach glass, people are drawn to the soft tropical colors and soft scent. The soaps have tropical pieces suspended in a clear bar. The beach glass colored salts have a wooden spoon with a watercolor wash attached to the side. All of the bath products are scented with the same light, clean, fresh fragrance. The Beach Glass Soap is perfect for bathrooms and guest rooms.


text:
Firewire FST Dominator Surfboard 6ft 1 FCS - White
Product Details
The rapid response flex memory in the Future Shapes Technology used in these boards yields great speed through the turns whilst the parabolic rail configuration guarantees 100% return memory for years.
Firewire surfboards feature some very distinct construction traits that set them aside form other boards currently available:
1) parabolic balsa rails
2) dual density EPS and advanced composite core
The parabolic balsa rails flex at the start of a turn storing energy and rebound through the turn releasing built up energy in the form of speed. The spring back of the parabolic rails to the original rocker triggers rapid acceleration, like an arrow shot from a bow. The construction materials, a unique formulation of hi-tech epoxy resins and advanced composites mean that these boards maintain the lively feel you get with brand new polyurethane boards, but are up to 20% lighter and will last 5+ times longer.
This manufacturing process has won environmental awards and has created a range of lightweight and durable custom boards that are quickly being recognised for their awesome performance.
The Dominator is the most adaptable board in the Firewire range, a real crowd pleaser, everyone should have one in thier quiver!
What this all means for surfers is a step forward in the age old trade off of performance versus durability that has traditionally limited polyurethane boards. The nature of the core technology in these boards allows them to rebound in and out of turns with little loss of speed. The secret to improved surfing is maintaining and using this speed to go higher, bigger, longer or whatever does it for you!
Thanks to 10 years of research and the expertise of shapers Nev Hyman and Dan Mann the future of surfing is changing, these guys are calling this Future Shapes Technology, we like it!
Why Buy From Boardshop?
- 100% Secure Shopping Guarantee
- Over 200 years combined experience
- We actually surf
- Best Price Promise
- UK Based Support
- Huge range of brands
- No quibble return policy
- Customer Reviews
- Delivery Information
- Returns
- Ask A Question
Overall Customer Rating
Ivan (reviewed 28/03/2018)
Peter (reviewed 19/10/2016)
Borh (reviewed 18/10/2016)
Very good purchase!!!
I love it guys, 100% recomendable.
Fabian (reviewed 06/08/2016)
Hannes (reviewed 08/02/2016)
Paul Mason (reviewed 20/01/2016)
The only downside is that if the Dominator is good at everything, it's not outstanding at anything. The BP is a better board for small, weak waves, and I have a 6'7" Sam Egan that's better in big surf. But you can't have everything! If you want a one-board quiver, this is it.
Note on size: as with all Firewires, smaller is better. I weigh 80kg and ride a 6'0"/34.9 litres. It's about right for me, a reasonably good surfer (decades of experience, not quite so much ability...); if I had to replace it, though, I'd probably think about the 5'10".
Mark Harland (reviewed 23/10/2015)
Thanks for getting this to me so quickly.
IceCoolMilkyT (reviewed 22/06/2015)
Big Red (reviewed 14/01/2015)
Steve Mock (reviewed 08/12/2014)
Enric (reviewed 17/11/2014)
Taylor (reviewed 09/07/2014)
Write Your Own Review
Delivery Options for Firewire FST Dominator Surfboard 6ft 1 FCS - White
What if I need to send something back for exchange or refund?
It's not a problem, all purchases on Boardshop.co.uk are covered by a 14 day exchange or refund guarantee. If you are not completely satisfied with your purchase it can be exchanged or the cost of the item(s) refunded. In case of all returns you will need to contact us for a returns number.
Please click here for further information.
Want to ask a question about the Firewire FST Dominator Surfboard 6ft 1 FCS - White?
Speak to a surfer about this board
At Boardshop we all surf, so we are able to give you real advice based on experience. It's more than likely we've surfed this board, so give us a call or drop us an email using the form.
You can always call us on the following number.
We are open Monday to Friday 8:30am to 5:30pm
Outside UK 0044 (0)1243 674250


text:
Our mobile site is optimized for smaller screens.
Thanks so much - your service is amazing- thanks so much for your help- Sanida A.
Just writing to let you know that we closed on the house today. Thank you for all of your help and support, it has been a great experience. Aaron S.
If it had not been for your help I would have not kept any of my equity.- Theresa J.
Derek Greene is the consummate professional and if you need help selling or listing a home he is the one to do it. There is none better. Brad W
Thank you for your prompt service-- you have exceeded my expectations.- Doug T.
I applaud your attention to detail. P.S. Already had 1 showing yesterday by the busiest and best closing Agent in the area. Your business model and using a Buyers Agent is a perfect fit.- Jon M.
Thank you so much you been wonderful to deal with definitely would use you in the future. - Rachael S.
Thank u so much. UR the BEST!!- Shelli W.
Thank you for your help and support to me, understanding that I'm not a tech person. Just wanted you to know that I appreciate it and you.- Jocelyn K.
Awesome! Your service is stellar! Very much appreciated.- Steve G.
The Greene Realty Group
| 4 Field Way , Worcester, MA 01602
Phone: 877-222-0621 | Fax: 9788820233 | Email: email@example.com
VT Real Estate Web Design


text:
STERLING – Imagine growing up without any photographs, heirlooms, records or keepsakes.
For foster kids – especially those moved from house to house – and adopted kids, entire chapters can disappear from their life stories.
Lutheran Social Services of Illinois is on a mission to save those memories. The nonprofit agency created lifebooks – a place for children to collect photographs, stories, and detailed information about who they are and where they come from.
Mary Sue Waite, 44, of Sterling, is a lifebook specialist for LSSI's Northern Illinois Region.
"When we look back, we pull out old pictures and look at things," Waite said. "For our kids, if the foster parents aren't tracking this stuff while they're separated from their biological parents, all that information is going to be lost. ...
They're going to lose their life, in a sense; they're going to lose their life story. And we all have a story to tell."
LSSI has helped more than 3,000 children – and their foster, adoptive and biological families – since starting the lifebook program in 2008. Now, lifebooks also are available to families not affiliated with LSSI.
The primary lifebook, "My Awesome Life," is a therapeutic tool for children who have experienced trauma or loss, Waite said.
"A lot of people think this is like a scrapbook," she said, "and it's different. … Scrapbooks usually just have good, fuzzy, warm feelings – like pictures and good memories."
Lifebooks capture the good, the bad and the ugly.
For example, kids journal about how they felt when removed from their parents, and why they think it happened. The process helps them make sense of their circumstances.
"They might blame themselves for coming into foster care when it's not their fault," Waite said.
Jennifer Shaw, 38, and her husband, the Rev. Joshua Shaw, 44, pastor of Hope Bible Fellowship in Dixon, are grateful for lifebooks.
In the last decade, the Dixon couple has opened their home and hearts to 38 foster children – boys and girls of any race from newborns to teenagers. They now care for one adopted child, one child in the adoption process, one foster child, three biological children, and a 19-year-old.
"It actually blesses us, in our opinion, more than we could ever bless them," said Jennifer, 38, a 1993 graduate of Sterling High School.
The Shaws have used lifebooks with children 5 and older to help them open up. At first, some are so untrusting that when Jennifer asks, "How was your day?" they shoot her a look that seems to say, "Why do you want to know?"
"They don't really want to be open," she said. "They don't really want to say anything."
Through lifebooks, however, foster kids have learned to trust the Shaws, and the Shaws have learned more about them. Jennifer tells them, "I care about you regardless of all this junk in your past," and "What happened to you is not your fault."
"The more they share with you, the more they learn to trust," she said.
The bright, colorful lifebooks contain up to five sections, depending on the child's situation. The first two can be used by any child, whether in foster care or not.
In section one, "About Me," kids write about their friends, feelings, likes and dislikes, favorite school subjects, fears and worries, heroes, and dreams. They also list their strengths and special qualities.
"A lot of kids have low self-esteem in foster care," Waite said.
This section also includes a copy of the child's birth certificate, a picture of his or her birthplace, important "firsts" typically found in baby books, and a record of schools attended.
Section two, "My Family," includes information about the child's biological family.
Children recognize gifts from their birth parents, such as talents or physical traits. They also learn their parents' age when they were born and their medical history. If parents are unavailable, Waite researches their background information.
This section includes a family tree; and photographs and memories of siblings who may or may not be separated. Children also share what they would write in a letter to Mom and a letter to Dad.
"It's a very emotional page for [foster children] to fill out because they don't know what to say," Waite said. "I've had kids sit before me [and] well up in tears. … They say things like, 'Do you ever think of me?'"
Section three, "Where I've Been ... Where I'm Going" is specifically for children in foster care. They write about all the places they have lived and the people and pets who lived with them.
Kids also acknowledge the reasons why they do not live with their parents – such as abuse or neglect – and ask questions.
"A lot of times, kids internalize things; they don't really talk about it," Waite said. "When they see it in a book or on a piece of paper, they say, 'Well, it must be OK to talk about."
Kids who bottle up their emotions are more likely to act out now and abuse drugs and alcohol later in life, Waite said. The goal is to to help them work through their problems so they can become healthy, productive adults.
Section four, "Going Home," is for foster children returning to their biological parents. They write down what they are happy and sad about; and what they are afraid of, such as a new school or a parent returning to old habits.
Section five, "Getting Adopted," is for children who never are returning home after foster care. It also can be used by families who adopted internationally.
It includes the date of adoption, an adoptive family tree, and pictures of the adoptive family. The adoptive parents also write a letter, expressing how much they love and want the child.
Kids journal their feelings about the adoption and ask questions such as, "Will I ever see my biological family again?"
In addition to a lifebook, every child in the LSSI program receives a white box and markers and stickers to decorate it. Inside, they can keep pictures, report cards – just about anything.
The lifebooks and boxes are personal items that the kids, who have lost so much, can own forever, Jennifer said.
"They love it," she said. "It's very dear to them."
For every child helped by LSSI, Lifebooks include a picture with Waite. She has worked for LSSI for more than 20 years as a supervisor, caseworker, and counselor.
"[Lifebook specialist] is the most rewarding position I've had at LSSI," she said.
Waite adores children, and believes helping them feel special and loved is her God-given purpose in life. She remembers every child's name and their likes and dislikes.
'I may have not had children of my own," she said, "but I have worked with probably thousands of children, and all them have been my kids."
To get a lifebook
"My Awesome Life" comes in several versions – for any child, for children in foster care, for children returning home from foster care, and for children being adopted from foster care.
For families outside the Lutheran Social Services of Illinois program, cost ranges from about $16 to $19, plus shipping and handling.
Go to www.lssi.org/lifebook to view sample pages, watch a video, place an order, or make a donation.
LSSI also provides a training DVD and curriculum for foster and adoptive parents and professionals in the field.
Contact LSSI at email@example.com or 847-635-4600 for more information.


text:
Welcome to the web home of Pearls Homeschool Moms Support Group. Pearls meets on the third Monday of each month to encourage and strengthen moms in their homeschool journey. The group is very Christ centered and focuses on encouraging one another to be wives, mothers, and friends whose foundations are built on Jesus Christ and His Word. Our monthly meetings include special speakers, menu planning and recipe ideas, how-to teaching sessions, curriculum ideas and sharing, and much more.
Children are welcome to attend and participate in activities that have been planned for them in rooms adjacent to the moms' meeting area. Sculpy clay, art supplies, books, puzzles, and board games are a few of the fun things provided.
Whether you are a new homeschool mom, investigating the idea of homeschooling in the future, or have been educating your children for 20 years you are welcome to join us for a monthly shot of encouragement.
Please be sure to check out our statements page. For more information, feel free to send an email and we will be happy to help.
Pearls meets the third Monday of each month, September through May, from 1:30 to 3:30 p.m. at Chardon Christian Fellowship, 401 South Hambden Street, Chardon, Ohio.


text:
|Montgomery, Pa.
|High School:
|Public Relations
2013: Played in 18 games with 13 starts during her junior year ... hit .243 with three runs scored, two RBI, a double, a triple and her first career home run ... notched nine hits in 37 at-bats ... notched a .405 slugging percentage ... was hit by three pitches ... had a .349 on-base percentage ... was solid in the field with a .947 fielding percentage ... had a career-high two hits in the March 21 game against Susquehanna ... had her first career home run in the April 21 game at Misericordia ... earned CAC All-Academic team honors.
2012: Played in 20 games with 10 starts ... hit .227 with five hits in 22 at-bats ... had two RBI and a double in her limited at-bats ... had a .273 slugging percentage ... had a .292 on-base percentage ... notched her first career extra base hit against Penn State Altoona on April 9.
2011: Saw action in four games coming off the bench in all of her appearances ... was hitless in her four at-bats ... played all four games in the outfield.
Personal: Is a public relations major and is a speech communication and visual communication minor ... is the daughter of Kenny and Kim Harer ... born on September 15, 1991 ... was a first team All-State outfielder at Montgomery High School after her senior year ... her Montgomery High School team was the state runner-up during her senior season ... is a member of the York College Dean's List ... was an NFCA Academic All-Star ... is a member of the Lambda Pi Eta Communications Honor Society ... also a member of the Alpha Chi National College Honor Society.


text:
ECafePro Full Version
eCafePro Server Full Version
Features includes:
* Three Payment Options: Prepaid, Postpaid, Promotion options
* Each Staff user has his own Access Level or restrictions for the eCafePro system.
* Different Member Type and discount
* Member Prepaid Function and Bonus Point Center
* Different Day/Time Rate, Game and Internet Rate Option...
* Flexible Currency Sign Format (eg. AUD, USD, RM, Rp, $)
* Taxation
* Products/Services Setup: Allow customers to order goods (foods, drink, scan...)
* Stock Report.
* Sales Report: View the report in any date range. Print it or export it to other format.
* Email Shift Report: Send the shift report/summary to specify email address
* Punch Clock - Staff User Working Duration & Salary Report.
* Receipt Printing
* Emergency Printing
* Event Log: Record every actions of the system.
* Restart/Shutdown Any or All Client PCs
* Transfer Selected Client Pc to Another Client PCs
* View/Capture the Motion/Screen of Selected PC
* Send Message to Any or All Client PCs
* Control Sound Volume of Any of the Client PCs
* Lock And Unlock Any or All Client PCs
* Waiting List
* Different icon viewing Option, large icons, small icon, list, details.
* Customise your own Icons and Background Color.
*Stability: All the records including clients login records will not affected by Power Down or System Problems.
*and much more...
eCafePro Client
*Disable Ctrl+Alt+Del and Alt+Tab
*Restrict/Release Mouse Moving Area
*Rotating Wallpaper
*Lock and Unlock Mode
*Send Message to Server
*Check Time Start and Duration.
*Prepaid Member Login and Logout
*Tweak and Security Function.
It's very easy to use all this features and functions!


text:
The Beauty of Letting Go
In general, I'm not an uneasy traveler, but two things can make me highly anxious. One: letting someone else decide where I'm going to stay. Two: staying someplace without Internet access. I was forced to face both fears in trips this year.
Like most Budget Travel readers, I enjoy the planning process just about as much as the trip itself. Uncovering a gorgeous little gem of a hotel that hasn't been written up anywhere—yet!—becomes something to brag about. Our collection of "Stylish Steals", the world's best new boutique hotels under $150, is filled with spots like that—every single one of them gets my enthusiastic stamp of approval (which editors here will tell you is not all that easy).
I had to let go in a big way, however, when it came to this year's upcoming holiday week in Palm Springs, Calif., with my extended family. My mother beat me to the process of sifting through rental listings. She found a Spanish estate with five bedrooms, a pool, and an outdoor fireplace, within walking distance of downtown. (Nice work, Mom!) But I can't say giving up control was comfortable. And vacationing with parents, sisters, and in-laws? That might not be the easiest thing, either. I'm hoping that Marjorie Ingall's sharp advice from her multigenerational trip to Mexico transfers and that letting go just a little will lead to some lasting, good memories.
On a smaller scale, this past September I found myself pushing my own internal boundaries, not totally by choice. My friends had spearheaded a house rental on the coast of Maine, and it didn't have Internet access (double whammy!). I could barely get a sense from the photos as to what it was like. Plus, there was talk of dial-up. Dial-up! As it happens, the dial-up didn't even work, and my BlackBerry somehow erased all of my e-mails mid-trip. I was disconnected—in all the right ways. And after just one hour of sitting on a diving board with a good novel, it was hard to remember what I'd been scared of in the first place.