text:
Shifting the Paradigm of Intersex Treatment
Download a pdf of this document that can be printed on a single sheet, double-sided.
Shifting the Paradigm of Intersex Treatment
Prepared by Alice Dreger, Ph.D., for the Intersex Society of North America
Key points of comparison |
What is intersex? |
Intersex is a rare anatomical abnormality which is highly likely to lead to great distress in the family and great distress for the person with an intersex condition. Intersex is pathological and requires immediate medical attention. |
Intersex is a relatively common anatomical variation from the "standard" male and female types; just as skin and hair color vary along a wide spectrum, so does sexual and reproductive anatomy. Intersex is neither a medical nor a social pathology. | |
Is gender determined by nature or nurture? |
Nurture. Virtually any child can be made into a boy or a girl if you just make the genitals look convincing. It doesn't matter what the genes, brain, hormones, and/or prenatal life are/were like. |
Both, surely, but that isn't the point. The point is that people with intersex conditions ought to be treated with the same basic ethical principles as everyone else—respect for their autonomy and self-determination, truth about their bodies and their lives, and freedom from discrimination. Physicians, researchers, and gender theorists should stop using people with intersex conditions in "nature/nurture" experiments or debates. | |
Are intersexed genitals a medical problem? |
Yes. Untreated intersex is highly likely to result in depression, suicide, and possibly homosexual orientation. Intersexed genitals must be "normalized" to whatever extent possible if these problems are to be avoided. |
No. Intersexed genitals are not a medical problem. They may signal an underlying metabolic concern, but they themselves are not diseased; they just look different. Metabolic concerns should be treated medically, but intersexed genitals are not in need of medical treatment. There is no evidence for the concealment paradigm, and there is evidence to the contrary. | |
What should be the medical response? |
The correct treatment for intersex is to "normalize" the abnormal genitals using surgical, hormonal, and other technologies. Doing so will eliminate the potential for parents' psychological distress. |
The whole family should receive psychosocial support (including referrals to peer support) and as much information as they can handle. True medical problems (like urinary infections and metabolic disorders) should be treated medically, but all non-essential treatments should wait until the person with an intersex condition can consent to them. | |
When should treatments designed to make a child's genitals look "normal" be done? |
As soon as possible because intersex is a psychosocial emergency. The longer you wait, the greater the trauma. |
ONLY if and when the intersexed person requests them, and then only after she or he has been fully informed of the risks and likely outcomes. These surgeries carry substantial risks to life, fertility, continence, and sensation. People with intersex conditions should be able to talk to others who have had the treatments to get their views. | |
What is motivating this treatment protocol? |
The belief that our society can't handle genital ambiguity or non-standard sexual variation. If we don't fix the genitals, the child with an intersex condition will be ostracized, ridiculed, and rejected, even by his or her own parents. |
The belief that the person with an intersex condition has the right to self determination where her or his body is concerned. Doing "normalizing" surgeries early without the individual's consent interferes with that right; many surgeries and hormone treatments are not reversible. The risks are substantial and should only be taken if the patient has consented. | | Should the parents' distress at their child's condition be treated with surgery on the child? | Yes, absolutely. Parents can and should consent to "normalizing" surgery so that they can fully accept and bond with their child. | Psychological distress is a legitimate concern and should be addressed by properly trained professionals. However, parental distress is not a sufficient reason to risk a child's life, fertility, continence, and sensation. | | How do you decide what gender to assign a newborn with an intersex condition? | The doctors decide based on medical tests. If the child has a Y chromosome and an adequate or "reconstructable" penis, the child will be assigned a male gender. (Newborns must have penises of 1 inch or larger if they are to be assigned the male gender.) If the child has a Y chromosome and an inadequate or "unreconstructable" penis according to doctors, the child will be assigned a female gender and surgically "reconstructed" as such. If the child has no Y chromosome, it will be assigned the female gender. The genitals will be surgically altered to look more like what doctors think female genitals should look like. This may include clitoral reduction surgeries and construction of a "vagina" (a hole). | The parents and extended family decide in consultation with the doctors. This approach does not advocate selecting a third or ambiguous gender.The child is assigned a female or male gender but only after tests (hormonal, genetic, diagnostic) have been done, parents have had a chance to talk with other parents and family members of children with intersex conditions, and the entire family has been offered peer support. We advocate assigning a male or female gender because intersex is not, and will never be, a discreet biological category any more than male or female is, and because assigning an "intersexed" gender would unnecessarily traumatize the child. The doctors and parents recognize, however, that gender assignment of infants with intersex conditions as male or female, as with assignment of any infant, is preliminary. Any child may decide later in life to change their gender assignment; but children with intersex conditions have significantly higher rates of gender transition than the general population, with or without treatment. That is a crucial reason why medically unnecessary surgeries should not be done without the patient's consent; the child with an intersex condition may later want genitals (either the ones they were born with or surgically constructed anatomy) different than what the doctors would have chosen. Surgically constructed genitals are extremely difficult if not impossible to "undo," and children altered at birth or in infancy are largely stuck with what doctors give them. | | Who should counsel the parents when a child with an intersex condition is born? | Intersex is a psychosocial emergency that can be alleviated by quick sex assignment and surgery to reinforce the assignment. Professional counseling is suggested but typically not provided. Peer counseling is typically not suggested or provided. | Intersex is a community and social concern requiring understanding and support. Counseling should begin as soon as the possibility of intersex arises and/or as soon as the family needs it. Professional counselors trained in sex and gender issues, family dynamics, and unexpected birth outcomes should be present. Families should also be actively connected with peer support. | | What should the person with an intersex condition be told when she or he is old enough to understand? | Very little, because telling all we know will just lead to gender confusion that all these surgeries were meant to avoid. Withhold information and records if necessary. Use vague language, like "we removed your twisted ovaries" instead of "we removed your testes" when speaking to a woman with AIS. | Everything known. The person with an intersex condition and parents have the right and responsibility to know as much about intersex conditions as their doctors do. Secrecy and lack of information lead to shame, trauma, and medical procedures that may be dangerous to the patient's health. Conversely, some people harmed by secrecy and shame may avoid future health care. For example, women with AIS may avoid medical care including needed hormone replacement therapy. | | What's wrong with the opposing paradigm? | Parents and peers might be uncomfortable with a child with ambiguous genitalia. Social institutions and settings like locker rooms, public restrooms, daycare centers, and schools will be brutal environments for an "abnormal" child. The person with an intersex condition might later wish that her or his parents had chosen to have her or his genitals "normalized". | The autonomy and right to self determination of the person with an intersex condition is violated by the surgery-centered model. In the concealment model, surgeries are done without truly obtaining consent; parents are often not told the failure rate of, lack of evidentiary support for, and alternatives to surgery. Social distress is a reason to change society, not the bodies of children. | | What is the ideal future of intersex? | Elimination via improved scientific and medical technologies. | Social acceptance of human diversity and an end to the idea that difference equals disease. | | Who are the proponents of each paradigm? | John Money and his followers, most pediatric urologists and pediatric endocrinologists, and many gynecologists and other health care practitioners. | Intersex activists and their supporters, ethicists, some legal scholars, medical historians, LGBT activists, feminists, and a growing number of clinicians. |
Copyright © ISNA 1993-2008


text:
Hello, I'm Winnie! I'm a lover of almond butter by the spoonfuls and avocado in all forms! I love exploring the outdoors, the latest and newest food spots but also cozying up to a warm cup of coffee at home!
B.S in Nutrition Dietetics.
Future Registered Dietitian.
I am here to share my passion about leading a balanced lifestyle through easy recipes, intuitive eating and enjoying the food experience! I love meeting new faces so hey, lets get to know one another! :)
All tagged pasta

subset: commoncrawl


text:
Common Criteria Certificate awarded for the ASR 1000 Family
We are very pleased to announce that the ASR 1000 family of routers has been evaluated using the Common Methodology for IT Security Evaluation (Version 3.1) for conformance to the Common Criteria for IT Security Evaluation (Version 3.1) and was awarded a Common Criteria Certificate by NIAP (National Information Assurance Partnership). The evaluation assurance level (EAL) for the product is EAL4 augmented with ALC_FLR.2.
The ASR 1000 is functionally compliant with three Protection Profiles:
- Router: U.S. Government Router Protection Profile For Medium Robustness Environments, version 1.1
- VPN: U.S. Government Virtual Private Network (VPN) Boundary Gateway Protection Profile For Medium Robustness Environments, version 1.2
- Firewall: U.S. Government Protection Profile for Traffic Filter Firewall For Medium Robustness Environments, version 1.1
In fact, the ASR 1000 is the only product in the market that is certified as a router, firewall and VPN device!
The following ASR 1000 platforms have been certified:
- ASR 1002 with ESP5 or ESP10
- ASR 1004 with RP1 or RP2 and ESP10 or ESP20
- ASR 1006 with dual RP1 or RP2 and dual ESP10 or ESP20
For more information about the certification, and for the security target document, validation report and actual certificate, please refer to the NIAP/CCEVS web site at http://www.niap-ccevs.org/st/vid10361.
For further information on Global Government Certifications, please visit here: http://www.cisco.com/web/strategy/government/sec_cert.html
In an effort to keep conversations fresh, Cisco Blogs closes comments after 60 days. Please visit the Cisco Blogs hub page for the latest content.


text:
Dan Walters
Dan Walters: Three candidates light way to possible GOP revival
They are not likely to win this year, but the California Republican Party has several candidates for statewide office who are lighting the way to a potential GOP revival down the road.
Neel Kashkari, Pete Peterson and Ashley Swearengin are relatively young, accomplished, articulate and moderate. They understand that hard-right bombast doesn't work in a state in which less than 30 percent of voters call themselves Republicans and moderate independents hold the balance of voting power.
They shun the anti-everything (immigrant, abortion rights, taxes) positions that many Republicans reflexively adopt, but that those independents reject, and embrace the pro-business, make-government-work-better attitudes that have worked for previous Republican winners.
Peterson, executive director of Pepperdine University's Davenport Institute for Public Engagement and Civic Leadership, is running for secretary of state, while Swearengin, mayor of Fresno, wants to become state controller, and both are likely to survive the top-two primary and make the November runoff.
Kashkari, who ran the federal government's TARP bank bailout program, is locked in a fierce primary duel with Tim Donnelly, a very conservative state assemblyman, for the right to challenge Gov. Jerry Brown.
Donnelly is off the wall in his condemnation of immigrants, his opposition to banning Confederate flags from being sold in state shops and, most recently, his suggestion (later withdrawn) that Kashkari, son of Indian American immigrants and a Hindu, had embraced Islamic Shariah law – but he has been leading Kashkari in the polls.
California Republican Party leaders clearly fear that in next month's primary, Donnelly could become the party's official candidate and make it an international laughingstock.
Therefore, without formally endorsing Kashkari, they want him to win the primary, while fully aware that he has almost no chance of unseating Brown.
It's not hyperbole to say that the future of the Republican Party in the nation's largest state is hanging in the balance.
The party is very close to hitting bottom, and whether it recaptures some relevance or fades into total obscurity may depend on its fielding a plausible array of candidates this year.
Conversely, of course, Democrats would like nothing better than Brown's running up a historic landslide over Donnelly in November, thus graphically demonstrating their complete dominance of the state.
Such dominance would not be healthy. No competition means that the narrow interests allied with the dominant party can have their way, regardless of the effect on the larger welfare of the state. And one-party rule of any political system invites the sort of self-serving arrogance that has landed three Democratic state senators in the criminal courts just this year.


text:
By Cynthia McMurry, KF8 Ecuador
Over the past year, I have learned valuable lessons about life, gotten to know myself better, greatly enriched my understanding of microfinance, observed the workings of the informal economy in Latin America, been touched by many clients' stories and experiences, and been proud to represent Kiva at four different MFIs in three South American countries.
Some of my favorite moments, though, have absolutely nothing to do with microfinance. They're little cultural quirks, lifestyle adaptations, or just silly everyday things that make me smile, remember that I am not from here, and cherish the experience that much more.
Some of my favorites:
Best heckle: Anyone who's as white as me and who has tried to run in public in Latin America knows what it's like to be heckled. You usually get whistles, catcalls, and hear things like, "Faster!" "Run!" and "ONE two three ONE two three." After a while you learn not to pay too much attention and to instead focus your energy on watching out for dogs and traffic.
Out running in Trujillo at 7am one morning, a driver stuck his head out the window and yelled "Yuquitas peladas!" ("Little peeled yuccas!"), a metaphorical reference to the whiteness of my legs. By far the most creative heckle ever, plus I'm impressed that he was able to think of it so quickly (especially that early in the morning) and stick his head out of the car window while driving and avoiding traffic mishaps. Kudos.
Best street foods: Grilled plantain with cheese (Ecuador), giant corn on the cob with cheese (Cusco), hand-churned muyuchi ice cream (Ayacucho), cow-heart kabobs (Bolivia/Peru).
Best market find: "Peanut paste" in Ecuador, which is supposed to be used to cook cow's stomach. When I told the woman I buy it from that I add salt and eat it on bread with jelly, she looked at me like I was nuts. Crazy gringos.
Best healthy eating tip: A loan officer in Santa Cruz, Bolivia once invited me to a glass of caldo de caña (sugar-cane juice), a thick, murky brown liquid that is sickeningly sweet, like drinking a glass of maple syrup. He says, "It's all natural, don't worry. They don't add any sugar to it."
I'm waiting for this to take off as the next fad diet in the States.
Best religious insight: A conversation I had with a loan officer:
Her: What religion are you?
Me: Oh, I'm not religious.
Her: Why not?
Me: Well, I just have a hard time believing that just one of the world's religions has all the right answers and all of the others are wrong.
Her: Yes, but if you think about it, the one thing they have in common is that they all lead you to Jesus Christ.
Best financial advice: Hoard change (thanks, Dan Kahn). You're only as rich as the amount of change in your pockets.
Most humbling idiomatic realization: I will never be done learning Spanish. Every time I think I've got it down, I change locations and chalas become sandalias become become zapatillas, or lapicero becomes bolígrafo becomes pluma becomes esfero, or caña becomes chaque becomes resaca becomes chuchaque. And aguacate and palta keep switching back and forth.Where on my resume should I indicate that I know four different words for pen?
Second most humbling idiomatic realization: After two months in Ecuador, I still don't know how to ask for the kind of bananas I want without pointing. I don't understand the difference between a platano, a banano, a guineo, a maduro and an orito. If anyone has pictures with labels it'd be greatly appreciated.
Best way to ask for directions: Most anywhere I want to walk to is immediately deemed too far away and/or too dangerous for a lolita like me to go on foot. In order to avoid answers like "Walk to the corner, hail a cab and tell the cab driver that's where you want to go," I've learned to strategically rephrase my requests for directions. Instead of asking, "How can I walk to this place?" I ask "How might Antonio Banderas ride a scooter to this place?"
Best way to tell Ecuadorians apart geographically: One day at the beach with the local branch manager, he pointed out that it's easy to distinguish locals from people from Quito who are in town on vacation. I looked around and wasn't so sure I could tell, so we started guessing with passers-by. He nodded to one middle-aged man, lounging in the back of his pickup truck with a tank top pulled up to his chest, exposing his sizeable beer belly, which he rubbed fondly.
"What about that guy?" said Fernando.
The gentleman in question looked pretty tan. "Mmmm… local?" I guessed.
He laughed. "A local would NEVER do that, Cynthia."
"What? I've seen tons of guys from the coast strutting around showing off their guts," I responded, confused.
"Yes," he said, "but never in Lycra."
Cynthia McMurry is a fourth-time Kiva fellow working with brand new Kiva field partner Fundación Espoir in Cuenca, Ecuador. Previously she worked with Fundación AgroCapital in Bolivia and FINCA Peru and Asociación Arariwa in Peru.
To search for currently fundraising loans from Fundación Espoir on Kiva, click here. No currently fundraising clients? Please check back soon! In the meantime, you can join Espoir's Kiva Lending Team here./>


text:
I'm planning to have a trip around in Peru and I was wondering if I can just reserve the hostels on the day I arrive in a new city or if I should call them a few days before. I'm traveling in April.
I can also try more than one hostel, of course I need to arrive before evening in each new location.


text:
Docent-Led Tours (for all ages)
Third Saturdays of the month
Tour begins at 11:00am and ends at noon.
Free for everyone. Pre-registration is suggested. Space is limited.
Join us each month to get a fresh look into the Museum's main exhibition through connecting conversations with one of our passionate docents. Learn the stories behind the work and talk "art" with ease as we bring people and art together.
Register at firstname.lastname@example.com.


text:
ss13 gallery director's cut
Piers Atkinson's designs are at the cutting edge of fashionable millinery. He has dressed Rihanna, Paloma Faith and members of the Royal Family in his elaborate and stylish couture hats and bespoke headpieces for concerts, festivals and weddings.
Piers Atkinson | Downs Rd, London, United Kingdom


text:
Engineering Materials: Properties and Selection
Prentice Hall, 2002 - Technology & Engineering - 818 pages
For courses in Metallurgy and Materials Science.
Co-authored by Kenneth G. Budinski and Michael K. Budinski, his son, with over 50 years of combined industry experience in the field, this practical, understandable introduction to engineering materials theory and industry-standard selection practices provides students with the working knowledge to (1) make an informed selection of materials for engineering applications and (2) correctly specify materials on drawings and purchasing documents. Encompassing all significant material systems metals, ceramics, plastics, and composites this text incorporates the most up-to-date information on material usage and availability, addresses the increasingly global nature of the field, and reflects the suggestions of numerous adopters of previous editions.
From inside the book
62 pages matching copper alloys in this book
Where's the rest of this book?
Results 1-3 of 62
What people are saying - Write a review
Other editions - View all
Engineering Materials: Properties and Selection
Kenneth G. Budinski,Michael K. Budinski
No preview available - 2002


text:
What's missing from Business Insider's list of the 10 cities whose pension funds are most in danger of running out of money? There are no California cities in the top 10. The methodology of the researchers relies heavily on the size of the unfunded obligation as a percentage of the population to gauge how endangered a pension fund is. Philadelphia, Chicago and Boston are 1-2-3 on this list.
But, you say, isn't the state of California in bigger trouble? Not according to these statistics. The state's pension funds don't make the top 10 list of state pension funds most in trouble. (#1 here is Illinois).
Such projections have limited value, in part because no one can know the future of the markets or the economy. And these projections depend on no changes to these funds (they assume 8 percent annual increases in benefits and three percent annual increases in the growth of the funds). But they do make the point that, for all the apocalyptic talk about pension obligations in California, we're very much in line with the rest of the country. Unfunded pension obligations are not just a California problem -- they're a national problem.
UPDATE (ON WHY THIS POST IS OFF-BASE): A wise colleague, who is an expert in pensions, argues convincingly that I'm conflating two related but separate things: the adequate funding of pension liabilities and the size of pensions.
Prop 162 has made the first not much of an issue, at least for CalPERS, the big pension fund for government employees. Prop 162 requires participating governments to make payments to fund the pensions. That's very different than states like Illinois, which haven't set aside the money to pay for pensions.
California's problem, my colleague notes, is the size of our promises. State and particularly local governments have made very big promises for pensions that require rising payments. In California, we'll pay for such pensions--but will have to take that money from things the public may want more.
In short, California has a different kind of pension problem than the states and cities on these lists.


text:
Chaat is the common term used for mouth watering street food in India. It has many varieties as gol guppe or pani puri, sev puri, dahi puri, chole tikki, papdi chaat, bhel puri. All of them has common mint-cilantro (green chutney) and tamarind (sweet imli) chutney. If you have all the ingredients, these chaats can be prepared in jiffy. I always keep green chutney and tamarind chutney ready in my refrigerator so preparing chaat is very easy.
The recipe here is for Sev puri dahi puri also called as SPDP, in Pune, India. I'm using store bought pani puri shells. They are as good as home made ones; sometimes even better:). These shells are versatiel, can be used with pani to eat as golguppe/ pani puri or can be prepared as sev puri dahi puri. The same recipe is also called sev batata puri beacuer the pani puri shells are filled with boiled potatoes. Enjoy this lip smacking snack.
For Sev puri dahi puri: Approx. 4 servings
- Plain Golguppe (pani puri shells) – 24
- Fine namkee sev– 2 cups
- Potatoes boiled – 2
- Sweet onion – 1 finely chopped
- Fresh cilantro – 1/2 cup finely chopped
- Tamarind chutney – 3/4 cup
Link for Tamarind Chutney:
- Green chutney – 1/2 cup [OPTIONAL]
Link for Green Chutney:
- Yogurt (dahi) -1 cup (add some salt and sugar)
- Chaat Masala – 1 tbsp
- Red chili powder – 1 tsp
- Salt as per taste
- Boil and peel potatoes. In a bowl, mash these potatoes roughly and add chaat masala and salt. Mix and keep aside.
- Finely cut sweet onions and fresh cilantro, keep aside.
- Prepare tamarind chutney and green chutney as directed. Keep aside.
- In a bowl, take yogurt; add some sugar and salt. Mix well. Keep aside.
- Now for final chaat assembly; first take puffed plain golguppe or Pani Puri and make a small hole in each of them. Fill each puri with boiled potatoes.
- Keep 6 Pani Puris in each plate. Add a ladle full of smooth yogurt mix on these puris.
- Now add a tsp tamarind chutney and green chutney on each puri.
- Top it off with chopped onions and fine namkeen sev.
- Finally garnish with fresh chopped cilantro, chaat masala, red chili powder and salt.
Enjoy this mouth watering chaat as soon as assembled, or it will get soggy.


text:
Saturday, October 30, 2010
Pinwheel Quilt- Blogger's Quilt Festival
I completed this pinwheel quilt in May of 2009 as a birthday gift for my sister-in-law, Jamie. I'll admit that it started as a wedding gift for her and my brother a year earlier, but got replaced by a food processor and put on the back burner for awhile. I had never made a quilt larger than child-sized before this one.
It was also the first time I had done half-square triangles. At the time, I didn't know that I should square them up before piecing them all together! Once I figured that out, everything came together.
I love looking back at photos of this quilt because it features so many of my favorite fabrics-- including orange mono pez, many Alexander Henry prints, and Prints Charming teardrops. Since making this quilt I've become more nervous about using fabrics that I love because I don't want to run out of them! And that's silly. So this quilt is a good reminder that there's no sense in hoarding fabrics. Don't leave those favorite fabrics folded on a shelf!
30 comments:
- Monica said...
I've got a pinwheel quilt in my list... gorgeous... I really think you can do no wrong!!
(you can call it the food-processor quilt... :)...)
- October 30, 2010 at 11:28 AM
- Trudi said...
It's a beautiful Pinwheels quilt, very pretty!
- October 30, 2010 at 12:26 PM
- Lisa said...
While the front is lovely the back is AMAZING!!! Nice job and I am sure they appreciated the food processor too ;-)
- October 30, 2010 at 12:26 PM
- Terry said...
The quilt is beautiful You always remember your first full size quilt. Use fabrics you like it's more fun.
If you can't part with them make a charm hexigon and begin your own memory quilt.
- October 30, 2010 at 12:52 PM
- Ariane said...
I love it! It's gorgeous!!! Thanks for sharing it with us!!!
- October 30, 2010 at 12:58 PM
- felicity said...
Pinwheels make everything awesome. This quilt is gorgeous, and your message is a good one - why are we saving that fabric?? MAKE SOMETHING!
- October 30, 2010 at 1:12 PM
- Poppyprint said...
That's a wonderful, energetic quilt. I adore pinwheels (and yes, that squaring up is very helpful!). Glad all is well, I was just going to email you to check in. Happy Hallowe'en!
- October 30, 2010 at 1:32 PM
- Kristie said...
Very pretty, and I love the back!
p.s. love your header :-)
Happy Festival!
- October 30, 2010 at 2:01 PM
- Leslie said...
i made a point of adding in some of my favorite fabrics into the cancer quilt i just made. what else do i hoard, i mean have them for, right?
this quilt is beautiful...the fabrics you used are amazing. that zebra print really caught my eye. love that!
- October 30, 2010 at 3:56 PM
- Cindy V. said...
i totally get what you mean about not wanting to use up your favorite fabrics, but your quilt is great inspiration for HOW to use them up! i love it!!
- October 30, 2010 at 5:30 PM
- Bellgirl said...
I like the philospohy of using your favorites so you can see them in the quilts! I'm about to make my first half-square ttriangle quilt, and I'm thinking of doing pinwheels, so it's lovely to see how beautifully yours turned out.
- October 30, 2010 at 5:54 PM
- elizabeth said...
I love this quilt - one of my favorite patterns. The back on yours is great!
- October 30, 2010 at 6:23 PM
- ktquilts said...
Love pinwheel scrappiness!!! Yup, that favorite fabric is for cutting!!!!
- October 30, 2010 at 6:38 PM
- Rebecca Johnson said...
I have wanted to do a giant pinwheel quilt for a while now..and you have inspired me to just do it!! Yours is so beautiful..amazing colours! and the back...well it could be a whole other quilt top... amazing! xx i wanna follow you and see whats next!
- October 30, 2010 at 8:25 PM
- Bellgirl said...
BTW I've started making myself little sewing accessories, like needlebooks or pincushions, out of my favorite fabric scraps, so I'll have them around even when I've used the rest- it makes me feel comfortable about using the yardage!
- October 30, 2010 at 10:47 PM
- Borderline Quilter said...
I love it...it's kind of simple and homely....don't you just love the look of a quilt when it's been washed, it looks so snuggley!
Best Wishes
Kay in Scoltand
- October 31, 2010 at 2:27 AM
- Marit said...
Lovely quilt! Good advice about using your favorite fabrics - and a hard one to follow...
; )
- October 31, 2010 at 3:00 AM
- quiltilicious said...
Like both the front and the back.
- October 31, 2010 at 4:26 AM
- Quiltbenaco said...
Queste girandole sono deliziose!
Ciao ciao Domenica
- October 31, 2010 at 9:16 AM
- Mom2three said...
Beautiful pinwheel! I love the bright colors. I'm going to dig through my stash and see what I come up with.
- October 31, 2010 at 12:18 PM
- Janet said...
Isn't it funny how a gift can go from being for a wedding to a birthday, or from a birth to a birthday, or from a gift to comfort a sick person to a memory for one passed on. Not funny I guess, more like perfect. Love your quilt!
- October 31, 2010 at 8:19 PM
- harleywife57 said...
beautiful !! I'm working on a pinwheel for my sister's Christmas gift and got 'stuck' ; couldn't decide whether to do a border , or just all pinwheels and your lovely quilt made my decision ..... no border ! NICE job !
- November 1, 2010 at 2:45 AM
- Dani said...
As always, your color/fabric choices are the best.
I have a horrible habit of saving fabric. I don't know why either. There is always another "must have" to take its place.
Glad to see you are still on the scene.
- November 1, 2010 at 2:37 PM
- Christine said...
I love pinwheel quilts and I love the fabrics you used in yours. What a nice gift!
- November 2, 2010 at 10:10 AM
- Karen said...
I never get tired of pinwheels!
I love the fabrics and colours you have chosen. It looks so fresh with the white.
It's a beautiful quilt!
- November 4, 2010 at 10:11 PM
- Jennie said...
Lovely, I always adore pinwheels. And I agree about using favorite fabrics, how can they really be loved if they're stuck on a shelf...and I'm off to break open a fat quarter bundle!
- November 5, 2010 at 4:44 PM
- SarahB said...
I love pinwheels! Your pieced back is great too!
- November 5, 2010 at 6:17 PM
- Vicki @ DottyJane said...
Pinwheels are so much fun! The pieced back is awesome, too. Great quilt!
- November 8, 2010 at 3:16 AM
- Rebekah said...
What a pretty quilt! The pinwheels are so cheery.
Loved your comment "started as a wedding gift but gave a food processor instead". We did the same thing for a wedding we attended this year (the cut quilt pieces are now in my closet waiting to be sewn together.)
- November 9, 2010 at 5:36 AM
What size did your quilt end up being and what size squares did you use, if you don't mind sharing? SEeking ideas for my mother's 60th birthday present and I've always wanted to make a pinwheel quilt! Yours is gorgeous and such an inspiration!
- November 10, 2011 at 6:55 AM


text:
0 Members and 1 Guest are viewing this topic.
It's a running gag.. you get the two 'jerks' of the movie going to this or that place.. only to walk into the 'blue moon'. Then the music starts up and a couple of guys swoop in to dance with them (It is a gay club.. lots of leather and such).
Can I join in on this if there is space?
The group game that you all seem to be working on.
I've posted a reply, and hope that its okay. Im not sure how long until my character is altered by the nanobots, thats up to you.
Hey the rp is up if you guy's arestill interested could you post soon?
Well, to join the game as one more of the students and join in as you ned me but have you set up an OOC thread? It seems wrong to discuss a game that's running here in the players wanted section.
Hi eavatar, threads like this one are fine for gathering interest about an up-coming game and planning things, but when a game begins and players discuss in-game issues you should create an OOC thead in the same forum as the game so that game-chat doesn't keep bumping threads like this one to the top of the plaayers wanted forum.
Understood. I just got confused because the starting post was about Eliza posting her rp ideas and the last ones were about an already set game
Page created in 0.086 seconds with 27 queries.


text:
Dodge Ram Advertisement Was 'Best of Show' Last Night
The words of Paul Harvey were part of the American media landscape for over 50 years. He had many supporters who enjoyed his insight and wisdom, and the gentle way he delivered it. In 2005 he received the Medal of Freedom for his lifetime of work in media. During WWII he was a reporter in the South Pacific. In 1945, he moved to Chicago, and worked on finding work for returning veterans. In 1946 Paul Harvey launched "The Rest of the Story" and these 15-20 minute nuggets of information and insight became part of radio for the next 50 plus years. Harvey died in 2009, there were never many like him before, and no one has taken his place since.
Below is an add that made use of a old Harvey tract and it was hands down the best of show for this years crop of super bowl adds, many of which were at best vapid and lame.
It is a shame that remainder of the adds were as lame as they were. Considering how expensive the advertisement slots are for a super bowl, one would have thought the producers of this vignettes would invest into producing something creative, in lieu of something simply crass.


text:
Set the controls for the heart of happiness
The eagle-eyed among you will have noticed there was no newsletter last weekend. Apologies. The reason for this is I have journeyed deep into the warm, pulsating heart of the happiness movement. Last Thursday I took part in a conference on Positive Psychology at Wellington College (the pioneer of well-being classes), and then I went down to Dartington, in Totnes, Devon, to take part in an Action for Happiness two-day happiness festival. I left Dartington, I kid you not, while a choir stood on the misty lawn singing 'happy, happy, happy clappy!' I felt like a rehab patient leaving the Priory.
Anyway, abandoning my usual dour demeanour, I admit that both events were great fun, and encouraging. My sense is that the Positive Psychology / happiness movement is becoming less positivistic (in other words, less dogmatic in its claims to objectivity and scientific truth) and more responsive to the role of philosophy and ethical reasoning in the search for the good life. (On that point, it's sad that Christopher Peterson, one of the more philosophical voices within Positive Psychology, died this week. Here's his beautiful last blog post).
I organised a philosophy discussion circle at Dartington - the first time I've facilitated one - and I think everyone involved really felt the benefit of that sort of open Socratic inquiry into what the good life means for us. As the Quakers well knew, there's something very egalitarian and democratic about a discussion circle - there's no expert or priest or higher authority 'up there' while the masses kneel beneath them. Everyone is equally at the front or at the centre. And facilitating a circle discussion seemed to involve letting go of control and letting silences happen - both quite difficult for me!
I also came away from the events hopeful that the Positive Psychology / happiness movement is aware of the risk that, in deifying certain emotional states or personality types as ideal, you pathologise their opposites. If you say that happiness is ideal, there's a risk that sadness becomes an unacceptable failure. If extroversion is absolutely good, then introversion could be deemed absolutely bad. If optimism is always healthy, then pessimism becomes toxic. That sort of thinking is far too black-and-white, and I believe it actually causes suffering rather than mitigating it, by making introverts or pessimists feel worse about themselves. After all, introverts and pessimists have important social roles to play too, particularly in chronically optimistic short-term societies like ours.
We have many different moods and dispositions, and sometimes the best way to transform the difficult ones is to accept them rather than demonise them. In the words of Rumi, in what I think might be my favourite poem:
Learn the alchemy true human beings know: the moment you accept what troubles you've been given, the door opens.
Welcome difficulty as a familiar comrade.
Joke with torment brought by a Friend.
Sorrows are the rags of old clothes and jackets that serve to cover, and then are taken off.
That undressing, and the beautiful naked body underneath, is the sweetness that comes after grief.
I've given a lot of talks in the last month or so on the relationship between ancient philosophy and CBT, and often someone in the audience criticises CBT for being shallow, simplistic, mechanistic, capitalist and 'not dealing with root causes'. Usually such critics are therapists or counsellors in other traditions, annoyed that they didn't get any public money. My answer is typically that I expect other forms of therapy to get public funding in the future - it's already happening for approaches like mindfulness therapy - but you can't expect to get any government funding without a convincing evidence base. Anecdotal case studies by psychologists simply won't cut it anymore. As Freud proved, they're too easy to fake.
It is also clear to me, however, that CBT is not for everyone and the research still has a long way to go to work out how to help more people. But what saddens me is that some therapists fail to find anything to celebrate in the government's new support for talking therapies. Nor do many lay-people see the young national mental health service as something to fight for. The Improved Access for Psychotherapies (IAPT) policy is still very young, and vulnerable (as Paul Burstow MP, former minister for care services, recently emphasised). We shouldn't assume it will stay in existence without our protection.
Richard Layard, the economist who more than anyone helped get IAPT funding, warned at Dartington that not all allocated funding is coming through and that as much as half of all children's therapy services are being closed (I've asked him for stats to back up that claim). It is a very recent phenomenon for government to take mental illnesses like depression and anxiety seriously. If you believe in talking therapies, not just CBT but any talking therapies, then please support IAPT. I am all for expanding the range of therapies available on the NHS, as long as they are evidence-based.
Meanwhile, one thing that struck me as we discussed various 'happiness policies' at Dartington, was how little anyone spoke of adult education. Likewise, not one political party mentioned adult education at their conference. Schools, academies, universities - they're all in the news constantly. But adult education is completely off the political radar at the moment. Adult education was a central part of the socialist vision for thinkers like RH Tawney. But no one in parliament cares about it now, none think it worth fighting for. At least Action for Happiness is trying to do something for adult education, albeit in a rather informal and unstructured way. It is a noble attempt to spread ideas about the good life and the good society - inspired, I believe, by Richard Layard's experience of attending a Quaker reading group for many years.
Talking of reviving adult education, we had a seminar at Queen Mary, University of London yesterday evening, in the beautiful Octagon Room, which was once a library for East End workers back in the 19th century when Queen Mary was known as the People's Palace. We had a great group of participants come and talk about their work - including Philosophy Now, Philosophy In the Pub, Skeptics In the Pub, Pub Psychology, Sapere (a charity that does a lot of work with Philosophy 4 Children), Niki Barbery Bleyleben (good name!) who runs discussion groups for mums, and many others. We videoed the presentations and will put them up soon, along with the report I'm writing on philosophy clubs, and the website, thephilosophyhub.com, which will finally launch next week, I promise!
One of the things I suggest in the report is that the contemporary grassroots philosophy movement is in part a product of the 1960s, and that decade's radical reformation of academia and demand that it 'look beyond the campus' (in the words of the Port Huron Statement). In that spirit, here is a 2008 BBC Radio 4 documentary by Nick Fraser on '1968: Philosophy in the streets', with contributions from philosophers including Simon Critchley and Alain Badiou.
One of the participants at our seminar was Paul Hains, who together with his wife Brigid recently launched the excellent online magazine Aeon. I'm not just saying that because he occasionally sponsors our philosophy club events - the essays it publishes are really very good. Check out this one by Ross Andersen (whose Atlantic articles on philosophy are typically excellent) on dendrochronology and the threats facing the oldest trees in the world
Here, from the Futility Closet blog, is some advice from 1820 on how to fight 'low spirits', in a letter from Sidney Smith to Lady Georgiana Morpeth:
Dear Lady Georgiana,
Nobody has suffered more from low spirits than I have done — so I feel for you. 1st. Live as well as you dare. 2nd. Go into the shower-bath with a small quantity of water at a temperature low enough to give you a slight sensation of cold, 75° or 80°. 3rd. Amusing books. 4th. Short views of human life — not further than dinner or tea. 5th. Be as busy as you can. 6th. See as much as you can of those friends who respect and like you. 7th. And of those acquaintances who amuse you. 8th. Make no secret of low spirits to your friends, but talk of them freely — they are always worse for dignified concealment. 9th. Attend to the effects tea and coffee produce upon you. 10th. Compare your lot with that of other people. 11th. Don't expect too much from human life — a sorry business at the best. 12th. Avoid poetry, dramatic representations (except comedy), music, serious novels, melancholy, sentimental people, and everything likely to excite feeling or emotion, not ending in active benevolence. 13th. Do good, and endeavour to please everybody of every degree. 14th. Be as much as you can in the open air without fatigue. 15th. Make the room where you commonly sit, gay and pleasant. 16th. Struggle by little and little against idleness. 17th. Don't be too severe upon yourself, or underrate yourself, but do yourself justice. 18th. Keep good blazing fires. 19th. Be firm and constant in the exercise of rational religion. 20th. Believe me, dear Lady Georgiana,
Very truly yours,
Sydney Smith
Did you see the BBC 2 series on the history of the stiff upper lip? It was excellent, and managed to get the history of emotions onto mainstream TV. Well done to my supervisor, Thomas Dixon, for contributing to the programme (he's now a leading historian of public crying, or a 'sobbing guru' as someone put it on Twitter). Check out the blog posts he wrote about the research behind the show.
Talking of stiff upper lips, a fortnight ago I participated in an excellent seminar on Stoicism and CBT at Exeter University. Here's a blog on Stoicism and its uses today that came out of it - expect some very good posts in the future from some of the seminar participants.
I admire Jenny Hartley and Sarah Turvey of the University of Roehampton for their pioneering work over the last decade on reading groups and book clubs. Their latest project is taking reading groups into prisons. They have expanded the number of such groups from 4 to 30. Great work.
Here's a BBC radio programme about the fast-developing science of hallucinations.
From 3 Quarks Daily, here's communitarian philosopher Charles Taylor in an hour-long discussion with Confucian philosopher Tu Weiming, asking if we're leaving the secular age.
And here's an essay with Tu Weiming explains why he thinks we're moving beyond the Enlightenment and philosophy is taking a 'spiritual turn'.
I've had some wonderful emails from people who have read the book over the last fortnight - thank you very much. It means a huge amount to me and makes me feel the hard work is worth it. You can help me in my work by buying the book for yourself or others, spreading the word, or writing a review on Amazon or Good Reads. We finally got an offer from the US (hooray! thanks for your support on that). There's still a lot of work to be done, so your help in promoting the book is hugely appreciated.
In the meantime, here is a photo of the nominees for this year's Booker Prize, with Will Self at the back showing how to do book promotion.
See you next week,


text:
You may have recently seen the 911 Audio Technica ad for their ATH-WS55 (Solid Bass Headphones) starring dancer Marqueese Scott. What you may have not know is that the music 'Reanimation ' was produced by fellow FL Studio producer Lenny D'Orlando. We caught up with him to learn more about the project.
Original Ad.
'Making of'. Cued to Lenny's interview
Tell us about yourself and how you got into music & FL Studio?
Hi, My name is Lenny D'Orlando; I am a 23-year-old professional music producer and sound designer based in Atlanta Ga. I started off by getting into music at a very young age by listening to my dad's music collection. He had all sorts of styles from ethnic and traditional all the way up to modern day pop. From there I picked up the guitar, eventually moving onto the piano and saxophone. By then I was truly addicted, and I grabbed as many instruments as I could get my hands on.
About the time I was a junior in high school, I discovered electronic dance music. A local college station would play re-runs of Armin van Buuren's A State of Trance, Carl Cox's Global Radio, and even John Digweed's "Transitions". When I first discovered this new sound, I couldn't get enough. I delved as deep as I could into these newly discovered genres spending every waking moment analyzing, dissecting, listening and understanding everything I could about the structure and sound of EDM. That's when a buddy of mine gave me a demo copy of FL Studio- that's when I discovered that art of producing. From there on, I was hooked. I immediately got the full version and I locked myself away in my room and spent day after day and night after night learning everything I could about the art of producing EDM in FL Studio. It's been about 5 maybe 6 years since I started producing, and now I feel like I've just about mastered the program. I can get it to do whatever I need to in multiple ways. I remember just getting into the program and thinking this was quite possibly the most complicated thing I've ever used, and now- I'm grateful that the possibilities are so vast within it. The flexibility along with the intuitive interface is bliss. I'm able to sit in my kitchen, eat a sandwich, have an idea pop into my head and minutes later have a bangin' track coming from my monitors, all because its so quick and easy to get ideas down. You can go from a rough demo to a polished piece of art all in one piece of software. It's fantastic and really gives the user an unbelievable amount of potential to grow, with out having to utilize tons and tons of different resources.
How did you get the gig for the Audio Technica ad?
I landed the Audio-Technica ad by way of a video production company I had worked with in the past. They've always kind of had this progressive edge to their style of work, in which I would generally accompany their videos with either electronic music, or music that had been inspired by edm. It always seemed to gel quite nicely. With that said, they called me up one day and asked if I could come to a meeting and sit down with a potential client to hash out some ideas. I of course said yes, and made my way down there. I sat down and minutes later Marquese, known to me as that guy in the 'pumped up kicks video', walks right through the door. Now, I'm not the kind of person to be start struck or become overly excited when I come across someone big, but when the idea of me writing a custom track was possible for this guy, in my mind, I started to get pretty excited.
So we sit down and speak with Marquese along with his manager and start brainstorming. Everything from dance moves, lighting, ambiance, emotion- all that jazz. As the conversation moves through all the visual and camera stuff, it eventually makes its way to audio and particularly music. They start bringing up tracks and bands/artists they wanted to use. First thing to pop up was the idea of using commercial music from artists like Skrillex, Datsik etc. That was quickly shot down due to the potential of licensing fee's being crazy expensive (our budget for the project wasn't very high). Then Marquese brings up the fact that his friends produce, and everybody was really digging the idea of incorporating Marquese's friends into the mix.
Reanimation Dubstep Project (click to see large)
So we listen to some demos of his friends' work and it wasn't really matching the feel of what we wanted- so that's when I chimed in and said, " Hey, I really think I can do this. I can match the feel and emotion of the story and even incorporate some hospital ambiance/sounds into the mix." I look up and felt a bunch of eyes staring at me, I could feel a little apprehension, like they weren't too sure they'd want to put all their eggs in one basket, but they willingly said ok… and even seemed somewhat excited about it!
Oh… Did I mention I only had 10 days to make the track before the video shoot? The pressure was on, so I holed myself up in my studio and started hashing out ideas and riffs. I spent the first few days trying to get melodic ideas to fit the overall tone of the video. I took a lot of inspiration from video game sounds and fusing them with modern sounds. I played with the idea of synthetic versus organic (seeing the music as synthetic was bringing a human back to life) and tried to fuse the sound equivalent of that idea into the song. When I got the initial melodic riff down, I moved onto designing basses. That was the hardest thing to do out of the whole project. I probably spent the better half of a week designing bass sounds all utilizing native FL plug-ins, no 3rd party plug-ins (outside of distortion). It was so much fun and rewarding. I was creating sounds I never dreamed of making. From there I started piecing the song together sending of demos as I went along. Eventually after many different arrangements, I finished it, and sent it off to my boss who then sent it to the client. They promptly called me back screaming about how much they loved it, and how excited they were to be using it! And that's how Audio 9-1-1 came to be more or less.
Note: You can ask Danny questions about his project here.
Any links you'd like to share?
ReAnimation/Audio 9-1-1 behind the scenes site: b055.thedvigroup.com <<< cool bonus features
My sites:


text: Thunderbird Thunderbird is a free, open source, cross-platform e-mail, news and instant messaging client. The project strategy is modeled after Mozilla Firefox. The addons extend Thunderbird's functionality making it by far the best email client ever made. zibusisomasuku • May 2017 • 0 agrees and 1 disagrees Disagree Agree Free Open Source Mac Windows Linux BSD PortableApps.com ... Haiku Extensible by Plugins/Extensions Built-in RSS reader Calendar integration Support for IMAP ... Multiple Account support Open Source apps SMTP integration Add-ons Built-in Calendar Categories Customizable Delivery reports Encryption Extensible by Plugins/Extensions Free API Gmail integration Google Calendar integration Import from Google Reader HTML Compose Integrated Chat Integrated Password Manager Integrated Web Browser Legacy addons support Open source software Export to OPML Import feeds from OPML Protected by Password POP3 Support Portable Secure File Sharing Tabbed interface Support for Themes Add a feature 1925 Like


text:
iPhone X/XS Case is in stock. We will print it as soon as you order it.
Ready to ship in 1-2 days
iPhone X/XS Case | Brand: Print Equipment | Material: Flexible black rubber
Product dimensions measured on a flatly laid out product.
Tip: measure an item of clothing at hand to compare.
Tea is the tonic of life so it makes sense the business owners are powered by tea


text:
NAKHON SI THAMMARAT, Thailand (AP) — The Thai government said Tuesday it could declare a security emergency in a district of southern Thailand to stamp out violent protests over low rubber prices, a day after dozens of police and demonstrators were injured in rioting.
Protesters demanding higher subsidies for rubber farmers hurled rocks, bricks and other objects at riot police and set fire to several police vehicles on Monday in the Cha-uat district of Nakhon Si Thammarat province. Some 77 policemen and at least 10 protesters were injured.
The violence erupted as police tried to move protesters who had blocked a traffic intersection. Protests started last month when thousands of rubber farmers blocked roads and railways in the south, where most of the country's rubber is grown.
Thailand is the world's top producer and exporter of natural rubber, which is used in products from condoms to car tires. Due to weaker demand in a sluggish global economy, prices for rubber have steadily dropped since peaking in 2011.
Last week, the Cabinet approved a 21.2 billion baht ($657 million) subsidy for rubber farmers. Most farmer groups have agreed in principle to the government's offer but hard-line groups have threatened to shut down a port, a border checkpoint and a major road junction in the south.
The protest site, 580 kilometers (360 miles) south of Bangkok, was calm on Tuesday, after provincial authorities declared the area "off-limits" to protesters by enacting a special security order, said Suporn Atthawong, a deputy secretary-general to Prime Minister Yingluck Shinawatra.
"The government is evaluating the situation," Suporn told reporters. "Security agencies will determine if other laws, such as the Internal Security Act, are needed."
The internal security law authorizes officials to seal off roads, take action against security threats, impose curfews and ban the use of electronic devices in designated areas. Peaceful and unarmed rallies are allowed under the law.
Police Maj. Gen. Somchai Uamthanom said the violence was mainly caused by teenagers who had joined the protests.


text:
The Re-Trial is now officially a "GO."
Melissa McKowan announced the people's intent to retry the case.
It APPEARS that Weinberg will be representing ayres again. In chambers (or at some point prior to today's hearing), dates for the re-trial were discussed, but none were selected, and in court, Weinberg then asked for a 2 week continuance before they make a decision.
McKowan stated the people's preference to just set the date, right then and there.
The judge granted the two week continuance, but clarified that they have already discussed potential dates, and that one of those will be selected, so there won't be any further "delay" of the retrial.
The continued hearing will be Friday, September 11th, 2009 at 9AM PST.
(Personal aside: September 11th is always a pretty difficult day for me. This will not be so great, but I'm guessing that McKowan probably suffered long and hard in chambers to keep Weinberg from getting 2 months continuance, so I'm not going to complain too loudly.)
ayres and his wife were present, along with Weinberg and his assistant.
There were 10 other people present in "public" part of the courtroom, at least 9 of whom are known to support the victims in the case. One of them was a juror in the original trial, and was greeted with a very cheerful "Good Morning!" from ayres as he hobbled (allegedly) into the courtroom with his walker.
One representative of the mainstream press was present, just as the judge was wrapping up.
[UPDATE 8/31/2009:] As of 11:26am today, the San Mateo County Times has updated their page to include a note that the "fundraising letter" that they discuss was first obtained by Victoria Balfour, and then reported on this blog on the 17th of July.
Superior Court Clerk's office: 650-599-1170
ayres' criminal case number:SC064366


text:
Urban Legend Detectives Case 3: The Kunekune (Dancing White Shadow) (Jp)
eBook (ePub)
Price: $2.00
This book is the Japanese version of "Urban Legend Detectives Case 3: The Kunekune (Dancing White Shadow)". The story is exactly the same, but the text in this book is written in Japanese for the people who need Japanese version. So if you want to read this work and its details in English, please check the English version of "Urban Legend Detectives Case 3: The Kunekune (Dancing White Shadow)". Also, this work was exclusively written as one of the made-in-Japan content belonging to The BBB: Breakthrough Bandwagon Books.
Available in ePub Format
Ratings & ReviewsLog in to review this item
There are no reviews for the current version of this product
There are no reviews for previous versions of this product
Product Details
- 9781312734739
- Copyright
- Kyosuke Tsumiki, The BBB: Breakthrough Bandwagon Books (Standard Copyright License)
- Edition
- Japanese First Edition
- Publisher
- The BBB: Breakthrough Bandwagon Books
- Published
- December 6, 2014
- Language
- Japanese
- File Format
- ePub
- File Size
- Product ID
- 21937811
Formats for this Ebook
|Required Software
|Any ePub Reader
|Supported Devices
|Windows PC/PocketPC, Mac OS, Linux OS, Apple iPhone/iPod Touch... (See More)
|# of Devices
|Flowing Text / Pages
|Flowing Text
|Learn more about ebook formats and e-readers
Your notification has been sent
Lulu Staff has been notified of a possible violation of the terms of our Membership Agreement. Our agents will determine if the content reported is inappropriate or not based on the guidelines provided and will then take action where needed.
Thank you for notifying us. We will email you with the results and/or actions taken as a result of the investigation if you chose to receive confirmation.
We were unable to complete your request.
We were unable to complete your request.
Listed In
More From
see more >
Age Verification
The page you are attempting to access contains content that is not intended for underage readers.
Please verify your birth date to continue.


text:
It appears ZA AV+FW 11.768 requires the installation of Microsoft .NET. True?
- When installing over 11.0.504 I received an error and the installation failed. I tried to post a png image, but was told it was not valid??? I had downloaded the installation file yesterday from http://server.iad.liveperson.net/hc/...10&action=view
- I could not get my computer to reboot, even in Safe Mode. Really upset me. On about the third attempt, computer did reboot in Safe Mode and I was able to restore to a Restore Point from earlier this morning. The new version ZA 11.768 showed as installed. I uninstalled using Revo, rebooted, ran clean.exe, cleaned up registry and hard drive, then installed ZA 11.0.504 and everything appears back as it was.
With ZA 11.0.504 installed, I can update, but I am not seeing the latest DAT file version as indicated in https://www.zonealarm.com/forums/sho...ista-Win7-Win8.
- I have run update several times
- My current DAT file version is shown below
Windows XP SP3 (fully up to date)
ZoneAlarm Free Antivirus + Firewall version: 11.0.000.504
Vsmon version: 11.0.000.504
Driver version: 11.0.000.504
Antivirus engine version: 126.96.36.199
Antivirus signature DAT file version: 1114142848
Web Identity Protections version: 1.5.393.22


text:
Jellybeans, chocolate eggs and spring-colored baskets are Easter staples. But candy isn't the only way to go. This year, think out-of-the-basket and create personalized Easter bundles for everyone in the family. Choose one of these creations, wrap it in cellophane, tie it with a big pastel bow, and it definitely qualifies as an Easter basket in our book!
- For Little Ones: Toddlers certainly don't need a whole basket full of candy. Instead, fill a sand pail with bath books, toys and bubble bath. Don't forget plastic Easter eggs, which make surprisingly great bath toys. Another alternative to the basket is to fill a toy dump truck with toys and other Easter goodies.
- For the Gardener: In lieu of a basket, use a watering can or decorate a terracotta pot. Add vegetable seeds, an herb plant and patterned gardening gloves. Including your favorite family vegetable recipes adds a personal touch.
- For the Chef: Buy a colander in a spring hue like mint, pink or pastel. Line it with a cheerful kitchen towel and add a jar of sauce, pasta and olive oil. For an added touch, buy Easter-shaped pasta from a gourmet food store.
- For the BBQ Aficionado: Line the bottom of a metal grill basket with charcoal. Fill it with barbecue sauces, marinades, rubs and grilling tools. Buy a plain apron from a craft supply store and have your kids draw an themed design.
- For the Sports Lover: Turn a baseball cap upside down and fill it with game day necessities like peanuts, sunscreen and a pair of tickets. If a hat won't hold all the goodies you want to include, go with a sport's duffle. Now you have room for water bottles, tennis balls and other gear.
- For the Art Lover: Create a personalized Easter basket for an art lover with coloring books, stickers, sidewalk chalk and other art supplies you can find at a Dollar Tree. Pack it in a canvas tote bag with fabric markers so kids can start creating immediately.
- For the Snack Lover: One of the problems with traditional Easter baskets is that come Monday morning, you have this big basket taking up space in your home. To fix that issue, fill a reusable, insulated lunchbox with treats or gourmet mustards, trail mixes, crackers and other snack items.
You can choose to keep it traditional or switch it up this year with a personalized Easter basket that will fit everyone in your family.


text:
Search for more flights to Boston (BOS)
Return: 04.02.2020
Return: 10.02.2020
Things to do in Boston
The largest city in New England, Boston is known as one of the best college towns and home to many significant U.S. historic sights. One day exploring this charming city will reveal why Boston is one of the most popular destinations in the United States.
Boston's top attractions
- Relax in Boston Common, the oldest park in America.
- Shop and dine at Faneuil Hall Marketplace, just a short walk from the Boston waterfront.
- Walk along the Freedom Trail for a tour of colonial Boston, starting at Boston Common and ending at the USS Constitution in Boston Harbor.
- Browse the shops and enjoy a meal at one of the upscale restaurants along Newbury Street.
- Take the family on a Boston Duck Tour or visit the Boston Tea Party Ships and Museum.
Best time to travel to Boston
Visit Boston during March for the St. Patrick's Day Parade in the South Boston neighborhood. During the summertime, visit Fenway Park to watch a Boston Red Sox game, or stroll through the Boston Public Garden with the family when the temperature is around 70 F (20 C). In the fall, see the leaves change with a walk through the many beautiful college campuses in the Boston area, including Harvard University, Boston College and MIT.
Find the best things to do in Boston.


text:
Ami said, I have six kids. When I had 2 kids I was good at it (school/read aloud/housecleaning/meals). When I had 4 kids I was capable. Now I am decidedly not.
I love my relationship with the Lord and truly glory in my weakness. I am so grateful that I am not in a performance based relationship with him But, here, in this flesh, on this earth, I have to get things done. And Jesus is not down here holding a crying one year old while I get dinner made And I don't remember how to educate or make meals anymore. So my question is, How do I do it? How do you redeem your days? What about when you forget how you used to function?
I find myself in the same boat, and I also wonder about the whys and wherefores of the change. How did I go from reading whole series aloud, to reading so little that finishing a chapter book is cause for celebration? Who am I, and where did the old Kim go?
I used to create a meal plan every week without fail, and now I can't seem to do it two weeks in a row. We did 6 subjects in school every day, and my house was generally clean. I read entire series of books aloud to my children. And I had 4, 5, or 6 little ones, with no help. What happened?
I think it really does get harder in some ways because as our children get older we are pulled in different directions. It's harder to find a book that will appeal to everyone at once, and it's harder to find the time to sit down and read – especially if what you are reading is not universally engrossing.
With 20 years of experience and several helpers, it's easy enough to put off planning and just wing it when it comes to meals – even though planning would save time and money.
There are enough of us to clean up after the little ones, so they don't have to learn to clean up after themselves.
And I'm not the 20-something I used to be. A sleepless baby can put me out of commission for most of the day.
How did I used to do it? How can I do it now? I can't by my own strength, but I never could. Just like the old days, I do my best and ask for grace and peace about the things left undone. Or I don't do my best, and ask forgiveness and help to do better tomorrow.
I ask my husband again about priorities so that we can be on the same page. I am blessed to have a husband who cares about lightening my burden, so he offers suggestions, pitches in to help, and rallies the troops. Maybe your husband will do this if he knows enough about your struggles?
From Tanya: We have a family of 10. And my laundry pile is huge! We have more clothes than we need but I am curious how much clothes, shoes, etc per person to keep. Do you have some sort of system for that? And do you get rid of clothing when there out grown or save it for a younger sibling?…at this point we are saving a lot but it doesn't seem to get used by the next either because the seasons are different or their body sizes are different. Also getting the kids to help with chores etc is like pulling teeth any thoughts on that also?…thanks
I strongly suspect we have too many clothes, but we do work hard to stay right on top of the dirty laundry. I hate when the washer goes out and it becomes an instant crisis because we were already operating on the cusp of disaster!
One thing that makes a big difference for us is to keep all the dirty laundry in one place, where I can see it easily. If it's out of sight, I forget about it entirely. If it's divided into a separate hamper for each bedroom or each person, we can be 12 loads behind before we know it! When it's all in one place right under my nose, "behind on laundry" means we have 3 or 4 loads to do.
Another thing that helps is not allowing the little ones to have free access to their clothes. Anyone young enough to enjoy a good game of dress-up is young enough to require supervision. When the 4yo needs fresh clothes, she has to ask first and have somebody watch her get them out of the drawer – so we know she isn't emptying her drawers onto the floor searching for her very pair of underpants.
I pass clothes directly from one child to the next whenever possible, because the "out of sight, out of mind" principle works here too. If we pack it up to save it, there's an excellent chance we will forget about it until it's no use to anyone. If we don't have a very near-term use for an article of clothing, we donate it and plan to buy again later from a thrift store.
How do you organize kids clothing? Anything you especially keep or don't keep?
Our clothes right now consist of 3 cubbies for each child, plus hanging space in the closet. The cubbies hold:
- Tops
- Underclothes & pjs
- Bottoms: pants, shorts
Some of us have a few more cubbies as the system has evolved, but that is basically how it works.
When it comes to hand-me-downs, I usually only keep what I expect to use within 2 years. That means I am keeping none of our 4yo daughter's clothes because we don't have another little girl up-and-coming. We try not to keep anything too worn or stained, of course, which means nearly all of the boys' clothes get pitched faster than they get passed. I keep just a few newborn outfits because they tend to receive them as gifts and use relatively few.
I also keep very few heavy coats or other winter apparel because they take so much space to store and we use them so rarely – sometimes we go the entire winter without needing more than a jacket, and most of my Texas-born children don't even know what a snowsuit is. I don't own anything heavier than a lightweight denim jacket myself. I just layer it with a sweater on the really "cold" days.
Ideas for healthy yet inexpensive snacks? I've got a boy who is 4 years old and could eat me out of house and home.
Most of our snacks are real food: anything that works for lunch works as a snack, too, and it probably has more staying power than traditional snack foods. I also lean heavily on milk as an add-on. It's a good balance of protein, fat and carbs. Peanut butter is another versatile source of protein. Anything with protein and fat will tend to keep kids satisfied for longer.
- Animal crackers and peanut butter
- Apples and peanut butter
- Banana bread with peanut butter
- Any appealing leftovers I'm eager to get rid of
- Banana roll-ups: spread peanut butter on a tortilla and wrap around a banana. If we happen to have extra hot dogs buns, we do this and call it a banana dog.
- Cake or muffins made of leftover oatmeal or other hot cereal. Serve with a big glass of milk.
- Peanut butter and jelly sandwich – heavy on the peanut butter (we keep tortillas on hand instead of bread, so ours are pbj roll-ups)
- Carrot sticks and ranch dressing
- Tortilla chips and salsa – the only chips we do in our house with any sort of regularity. We buy these in a big box from Costco, very cheap and much better for you than potato chips. Maybe it's weird outside of Texas, but my little ones beg for salsa.
- Peanut butter and banana smoothies
How would you answer these questions? See what questions the other moms are answering today:
- Smockity Frocks
- Raising Olives (currently posting once/month)
- The Common Room


text:
The Yonder Hill Campground in Madison, Maine, used to be filled to capacity every summer night with recreational vehicles. But that was years ago. RV owners have found they can skip the $36 campground fee and park overnight at the Skowhegan Wal-Mart for free.
The campground's owner, Allen York, said he often sees 25 to 30 RVs parked at the Wal-Mart.
In recent years, he said, there has been a cultural shift in how RVers travel, influenced in part by websites that use searchable databases to guide RVers to free parking spots, according to the Central Maine Morning Sentinel, Augusta.
"What has happened is nothing short of a phenomenon," York said. "All of a sudden, we are looking at empty lots when we should be in the prime season."
The owners of the state's 275 campgrounds are pushing legislation that would ban RVs from parking overnight at commercial lots, such as Wal-Mart. The Legislature's Health and Human Services committee voted 8-2 to endorse the bill, L.D. 114, which may come up for a vote in the House this week.
Proponents say the measure would help local campgrounds and RV parks stay in business and also allow the state to recoup nearly $1 million in lost state lodging taxes. They say it's unfair that licensed campgrounds must comply with regulations, such as supplying drinking water and waste-removal facilities, while parking lot owners don't.
For the campground owners, the enemy is Wal-Mart, which has a national policy allowing RVs to park overnight in most of its parking lots. While Wal-Mart doesn't charge a fee, it does make money when people shop at the stores.
"It's Goliath versus David," said Rick Abare, executive director of the Maine Campground Owners Association, which has 220 members. "This is the monster versus the little guy."
Wal-Mart by tradition has offered free parking to RV owners as part of an effort to serve communities, said Alexandra Serra, a lobbyist for Wal-Mart, which has 24 stores in Maine. She said the company has never had any problems with RVs staying on its Maine properties and welcomes them.
Nevertheless, Wal-Mart is not fighting the bill, she said. "Wal-Mart is going to do whatever the Legislature tells us to do, of course, and happily so."
While Wal-Mart is staying on the sidelines, RVers around the nation are mobilizing. News about the legislation has spread via the Internet on message boards and newsletters. People are sending e-mails and making phone calls to legislators, Gov. John Baldacci's office, the Maine State Chamber of Commerce and Maine tourism offices.
If it passes, Maine would become the first state in the nation to ban RVs from commercial parking lots. Similar bills in Montana and Nevada were defeated after protests from RVers, according to a press release by the Escapees RV Club, a Texas-based club with 32,000 members nationally.
"If this legislation passes, it may well set a precedent for the rest of the country, and we could see our freedom to choose where we park permanently revoked!" the club said in an electronic newsletter.
The callers are delivering a simple message: If the Legislature passes this bill, RVers will no longer to come to Maine. "I like Maine. I want to visit there. But I don't want to be told I have to pay to camp," said Jim O'Briant of California, who administers www.overnightrvparking.com, which tells RVers were they can park for free.
The site lists more than 30 Maine locations where RVers can park overnight for free, including L.L. Bean in Freeport, Dysart's truck stop in Hermon, DeLorme in Yarmouth and the Kittery Trading Post.
The Wal-Mart in Scarborough is not listed because the town has a municipal ordinance banning overnight parking. David Labbe, a senior official at the Kittery Trading Post, said that allowing RVers to park in the store's lot is just good customer service. For many RVers, the store is a destination stop, he said.
"They are on their way from Florida to Canada and want to get off the highway and park in our parking lot, which is safe and convenient," he said. "And they are on their way the next day. What's wrong with that?"
But York said he's seen RVers park at Wal-Mart in Skowhegan for four or five days at a time. He said they sometimes come to his campground wanting to pump out their waste tanks, but he turns them away.
The bill's sponsor, Rep. Anne Perry, D-Calais, said state law requires that businesses obtain campground licenses if they receive compensation from four or more RVs at a time, either directly or indirectly. She said the law is difficult to enforce.
She said that local police, though, could easily enforce an outright ban. Her bill calls for a one-time warning followed by a $100 fine. She said there have been isolated incidents of RVs at parking lots dumping waste into storm drains.
She wants RVers to feel welcome in Maine, she said. But if RVers avoid the state because they aren't allowed to park for free, that's not a great loss.
"If they are parking one night in parking lots, they are not staying in Maine," she said. "They are driving through."


text:
United States
Language: English
Our website uses functional cookies that do not collect any personal information or track your browsing activity. When you select your country, you agree that we can place these functional cookies on your device.
We've detected that you are using an older version of Internet Explorer. Your commerce experience may be limited. Please update your browser to Internet Explorer 11 or above.
Your Account
To protect your privacy, your account will be locked after 6 failed attempts. After that, you will need to contact Customer Service to unlock your account.
You have 4 remaining attempts.
You have 3 remaining attempts.
You have 2 remaining attempts.
You have 1 remaining attempt.
Contact Customer Service
Forgot Password?
To protect your privacy, your account has been locked after 6 failed login attempts.
Please contact Customer Service to unlock your account.
Username not found.
This field is required.
A password reset email has been sent to the primary email address associated with your account.
There was an issue with the password reset process. Please try again or contact Customer Service.
You have successfully reset your password.
Log in with Your New Password
There was an issue resetting your password. Please try again or contact Customer Service.
Contact Customer Service
You have not verified your email address. A verified email address is required to access the full functionality of your Promega.com account.
Resend Verification Email
There was an issue logging into your account. Please try again or contact Customer Service.
A verification email has been sent to the primary email address associated with your account.
There was an issue sending the verification email. Please try again or contact Customer Service.
Congratulations! You've created a Promega.com account.
Check your inbox to complete email verification.
Note: You will not be able to access your account until your email is verified.
Our records indicate that this email address is already registered.
There was an issue creating your account. Please try again or contact Customer Service.
There was an error processing your request. Please check your network settings and try again.
Thank you for verifying your email address.
There was an issue verifying your email address. Please try again or contact Customer Service.
Cell Biology
Nucleic Acid Analysis
Drug Development
Human Identification + Forensics
Lab Equipment + Supplies
Molecular Diagnostics
Protein Analysis
Applied Sciences
Clinical Research + Diagnostics
3D Models
Manufacturing Capabilities
Automation Solutions
Onsite Stocking
Articles, Blogs + Posters
Calculators + Tools
Student Resources
Events, Training + Webinars
Peer Reviewed Literature
Product Usage Information
Software + Firmware
Global Support
Our customer and technical support experts are here to help!
Local Sales Support
Get in touch with a nearby distributor or sales representative
Your Cart
Current Items 0
Charlotte J. Word
Consultant in Human DNA Identification Testing
Gaithersburg, Maryland, USA
The interpretation of a mixed DNA profile generated with any number of kits for the amplification of nuclear autosomal DNA can be simple and straightforward under the following scenario:
A DNA profile from such a scenario is shown in Figure 1. Here there are no more than four alleles at any locus, and peak height ratios are consistent with only two sources at all loci (e.g., fairly balanced and uniform peak height ratios at loci with four alleles and altered peak height ratios consistent with shared alleles at all loci with two or three alleles). It is thus reasonable to assume that there are only two sources of DNA in this profile. DNA analysts can interpret these data and calculate statistical frequencies with great confidence.
0.5ng of total DNA from a 1:1 mixture of DNA from two sources was amplified with the Promega PowerPlex® 16 HS System. One microliter of amplified product in 10µl of Hi-Di™ formamide/ILS was injected on an Applied Biosystems 3130xl Genetic Analyzer, and the data were analyzed using GeneMapper® ID-X. All alleles from both sources are present.
As the difference in the amount of the DNA contributed by the two sources increases, there becomes a point at which a clear major profile emerges that for all purposes can be treated as a single-source profile for interpretation and statistical calculations—the simplest scenario (Figure 2). Under this situation, the minor contributor's profile also may be complete and easily interpreted (with the possible exception of shared alleles) or may be incomplete and more difficult to interpret as the disparity in the amounts of DNA from the two sources increases and alleles drop below the analytical and/or stochastic thresholds.
0.5ng of total DNA from a 9:1 mixture of DNA from the same two sources as in Figure 1 were amplified with the Promega PowerPlex® 16 HS System and processed as in Figure 1. All alleles from both the major DNA source and minor DNA source are present.
In many cases, minor alterations in one or more of the parameters listed in the first paragraph may have a minimal effect on the ability to confidently interpret a mixed DNA profile, especially if the amount of each DNA amplified is sufficient. Some three-person mixtures can be fairly easy to interpret, particularly if the individuals are unrelated and have few alleles in common and there are two "major" sources. Interpretation becomes even simpler if one of the sources is known (e.g., fluid and/or cells, fingernail or swab taken from an individual) and the profile from that individual can be removed easily, leaving two decipherable profiles. Limited degradation that only affects one or a few of the loci with the longest DNA sequences may have little effect on interpretation, particularly if the data from those loci can be recovered by a second amplification with more of the same DNA or by using mini-STRs. A single stutter peak or artifact generally has no impact on interpretation of the DNA profile(s) from the major source(s). On the other hand, significant alterations to any of the parameters listed (e.g., increasing the relatedness or number of alleles shared among the sources, increasing the number of contributors and/or the disparity in the amount of DNA from each source, an increase in the amount of degradation and/or presence of artifacts) will likely make mixture interpretation more complex; a combination of several alterations generally confounds the interpretation significantly.
The most problematic scenario for mixture interpretation, however, is when the amount of DNA amplified is limiting for one or more of the sources in a mixture. Interpretation of the DNA profile from the limited source(s) can become difficult to impossible due to the inability to confidently detect stochastic effects that may be present. Stochastic effects can result in any of the following observations in the mixed DNA profile:
Three replicate aliquots of 1ng of a single-source DNA from a combined DNA plus master mix solution was amplified with the Applied Biosystems Identifiler® kit. One microliter was injected for 2 seconds on an Applied Biosystems 3130 Genetic Analyzer, and the data were analyzed using GeneMapper® ID-X. All variation in peak heights and peak height imbalance is due to variability in amplification, pipetting and electrokinetic injection.
From the data alone, it is reasonable to assume that the profile in Figure 1 does not suffer any stochastic effects and thus contains all alleles from the contributing sources based on the peak heights present. If all alleles from a known individual are present in this mixture, then that individual is included as a possible source. In contrast, the absence in this mixture of one allele (and certainly more) that is present in the profile from a known individual warrants excluding the individual as a source. However, the minor source of DNA in Figure 2 has some alleles with lower peak heights that may be near or below the stochastic threshold, introducing some possibility that the profile may be incomplete. In addition, some unlabeled stutter peaks at similar heights to the detected minor alleles also may need to be considered in the interpretation and statistical calculations. Restricting genotypes for a single minor contributor is simple at a few loci (e.g., TH01, Penta E) but more complex at others (e.g., D18S51, D16S539); restricting genotypes if there were two minor sources of DNA would be impossible.
Where it is difficult to reasonably assume the number of contributors due to shared alleles and/or limiting amounts of DNA with associated stochastic effects, it is important to consider the profile under different assumptions when the comparison is made to a known individual's profile. Caution should be used in declaring that a major source profile is present, as the highest peaks may simply represent the additive effect of alleles shared by two or more of the sources. It may be necessary to report the conclusions using different assumptions (e.g., mixture of two sources vs. mixture of three sources). This is especially true if the conclusions for an individual being compared to the evidence profile change under the different assumptions (e.g., excluded if two sources vs. included or inconclusive if three or more sources of DNA).
Due to the complications inherent in interpretation of partial and/or complex mixed DNA profiles, it is imperative that all profiles are thoroughly assessed and that the alleles relied on for interpretation and calculation for statistical frequencies be recorded prior to any comparison to profiles from known individuals. It might be helpful to record (e.g., on a worksheet) any decisions made during the assessment of the profile for reference at a later time (e.g., discussions with technical reviewer, technical leader or attorney(s), or during testimony) and establish the assumptions that may be used during interpretation and reporting. Similarly, determinations that a profile is unsuitable for interpretation and comparison should be made prior to referencing any known profiles. These steps will help ensure that no bias is introduced during the final interpretation process.
The DNA tests that we routinely use in our laboratories are designed to be exclusionary tests. That is, testing is performed under the premise that an individual who is not the source of the DNA with a single-source profile or who is not one of the sources in a mixture of DNA is expected to be excluded from the DNA sample. This premise holds true when a complete multi-locus single-source profile is obtained. However, as the number of sources in a mixture increases along with the concomitant increase in the number of alleles to interpret, and as the relatedness of a non-source to a true source increases, the ability to exclude a falsely accused individual decreases. The statement of "inclusion" under these scenarios may have little meaning, and the frequency of the mixed DNA profile results may be quite common. "Inconclusive" or "insufficient for comparison purposes" may be the more appropriate conclusion in some cases.
Similarly, as the quality of a DNA profile decreases (e.g., partial profile) the number of loci available for interpretation also decreases with the concomitant increase in the number of inconclusive loci, and again, the ability to exclude a falsely accused individual decreases. Fortunately, the statistical significance of the inclusion decreases proportionally; however, caution should always be used to ensure that strict guidelines for inclusion vs. exclusion (and inconclusive) are followed. Statements of inclusion and exclusion have powerful ramifications in our justice system. Care must be taken to provide all parties (e.g., law enforcement, attorneys for both sides and the judge and jury if the evidence makes it to court) a clear understanding of the limitations of a multiple-source mixture and the meaning of an inclusion or an exclusion for a particular sample in the context of the case. This is especially important when the "match" is a partial inclusion of a partial profile with statistical frequencies that are not rare. The term "cannot be excluded" really means the same as "included"; these statements are synonymous conclusions, and thus, always should be followed by appropriate statistical calculations. When there is a temptation to report "cannot be excluded" instead of reporting that an individual is "included as a (possible) source", be aware that there is some likelihood that a bias against exclusion or inconclusive and pro-inclusion may be favored. In some cases, either of these statements of non-exclusion can be compelling (and possibly misinterpreted as statements of identification of the source) regardless of the associated statistical frequencies.
For samples where there is an uncertainty regarding the number of DNA sources and whether the profile is partial or complete, mixture interpretation can be difficult and analysts may have differing opinions on how to interpret the data. In this situation, amplifying more DNA and/or extracting DNA from other regions of the item or from separate items in the case may prove beneficial.
There is an extensive list of publications relevant to DNA mixture interpretation in forensic cases (1,2). These studies may be used by forensic laboratories in conjunction with well-designed and carefully reviewed internal validation studies to establish effective standard procedures for DNA-testing parameters and their appropriate associated mixture-interpretation policies. Sensitivity studies and mixture studies covering all ranges of DNA tested under all parameters in the laboratory can provide a strong foundation to the laboratory for assessing the range of peak height ratios and stutter percentages routinely observed in the laboratory and for establishing appropriate analytical and stochastic thresholds for data analysis along with rigorous guidelines for consistent profile interpretation and statistical frequency calculations. Casework profile data using samples from known individuals may be used to enhance the established procedures by providing valuable perspectives on the limitations and parameters of DNA mixture interpretations. These measures, used in tandem with a comprehensive analyst training program, help ensure interpretation and reporting consistency throughout a laboratory. This is turn results in neutral, reproducible and accurate interpretation of the available DNA profile data.
Thank you to Martin Ensenberger of Promega Corporation and to Dr. Robin Cotton of Boston University for generously providing the profiles for the figures, and to Todd Bille, John Butler, Mike Coble, Robin Cotton and Catherine Grgicak for very helpful discussions on mixture interpretation.
Scientific Style and Format, 7th edition, 2006
Word, C.J.
Mixture Interpretation: Why is it Sometimes So Hard?
[Internet] 2011. [cited: year, month, date]. Available from:
American Medical Association, Manual of Style, 10th edition, 2007
Word, C.J.
Mixture Interpretation: Why is it Sometimes So Hard?
Promega Corporation Web site.
Updated 2011.
Accessed Month Day, Year.
Contribution of an article to Profiles in DNA does not constitute an endorsement of Promega products.
PowerPlex is a registered trademark of Promega Corporation.
Products may be covered by pending or issued patents or may have certain limitations. More information.
All prices and specifications are subject to change without prior notice.
Product claims are subject to change. Please contact Promega Technical Services or access the Promega online catalog for the most up-to-date information on Promega products.


text:
|Surely I'm not supposed to be a 'choirboy'? That's not very scary...
|...and a 'priest' is even less intimidating!
|Making me into a 'woman' would be scary...but not very relevant to Halloween...
|...Although I quite like the idea of becoming 'Stevie Wonder'. "I just called, to say, I love FOOD".
|Things were taking a turn towards the bizarre. I looked like I was dressed to play snooker.
|And what the heck am I supposed to be now? Amish?
|A 'highwayman'?
|Finally it all became clear. I'm a swashbuckling pirate like Jack Sparrow.
|But I'm much better looking than Johnny Depp!
|My name is 'Horrible Homer - the hooked hooligan of the high seas'. (But you can call me Homer for short).
|"Yahaarrr me hearties...a Happy Halloween to you all!"