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Truck & Off-Highway Engineering
Truck & Off Highway Engineering magazine is published for domestic and international manufacturers of various types of off-highway vehicle systems and the producers of the parts components, and materials that go into them. It is written for off-highway industry engineers, designers, and technical managers. Editorial material covers advances in off-highway technology that can actually be applied to the development of new and improved vehicle systems. Also presented are several product-oriented departments that present overviews of new vehicles, design concepts, and products with intriguing technological gains. Special departments include In the News, Industry Events, Off-Road Computing, Original Equipment, Technical Innovations and Tools of the Trade.


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Sometimes the best gifts come in small packages. Our amazing line-up of exquisite mini cakes is no exception. Alongside our incredible selection of delightful gourmet gifts you'll also find a wonderful variety of mini treats and gift ideas. From personal sized cheesecakes, to dreamy cupcakes and fudgy cake pops, we've taken everyone's favorite cakes and miniaturized them.
Calling all cheesecake lovers! It's time to dive into your very own whipped cheese dessert and check out our outstanding collection of personal-sized mini cheesecakes. Think sumptuous classic New York cheesecake, or scrumptious chocolate cheesecake and delicious rocky road cheesecake. These are just a few of the delicious ways to enjoy a mini cheesecake the Shari's Berries way.
And of course it wouldn't be Shari's Berries if we didn't offer a few berry delicious berry and cake duo assortments! No wonder then that when you browse our small cakes for sale you'll also find a great range of hand-dipped strawberries and cakes. Perfect for wrapping up a dessert delivery with a romantic feel or for simply surprising a chocolate strawberry lover, you'll love the signature chocolate berries we have in store.
On the hunt for the ultimate, classic small cake surprise? Then look no further than our range of gourmet cupcakes! Available in a luscious line-up of chocolate, vanilla and deluxe red velvet flavors, just tell us whether you would prefer selections of eight, 12 or 16 cupcakes and we'll create the perfect cupcake gift. Toasting a truly special occasion? Then why not try out our irresistible cupcakes delivered for a taste mini-cake heaven. Personal-sized presents don't get any more sophisticated than this! Just take a peek at our unbeatable cupcake selection and you're guaranteed to always find something new and fresh to tempt your palette -- from fun seasonal picks, to new flavors and decorative selection platters.
Small, miniature, petite – whatever you prefer to call our small cakes, you'll find so many ways to enjoy them! Order a selection for a dinner party with a sophisticated spin, send a gift box full to a friend or loved one for the ultimate birthday gift with a sweet touch, or simply buy a few for your next party.
There's nowhere better way to buy cakes online and when you shop Shari's Berries, you can expect the best. From using the most premium and deluxe ingredients, to offering the most exciting classic and contemporary cake and dessert recipes, there's no small detail that we haven't thought of. Give a gourmet cake gift that's small in size but big in flavor.

subset: commoncrawl


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The Mecum Kissimmee, which began this past weekend, is shaping up to be quite a spectacle with beautiful vehicles crossing the block every day, and this coming weekend will be no different. The beautiful '71 Hemi 'Cuda pictured here will be up for grabs this coming Saturday at 2:50 p.m.
The 'Cuda is one of 107 built with a 426 powerplant (producing 425 horses) and a hardtop. The Hemi option bumped the price of the 'Cuda coupe by $884, and brought with it a functional Shaker hood scoop, heavy-duty suspension and brakes, and a special transmission as well as the Dana 60 rear end. The California car is completely unrestored and features a matching numbers engine, transmission, and Dana 4.10 rear end Super Track Pack, and to make it even more rare, the car is one of only 59 built with a 4-speed manual transmission.
Hold-down pins, a rubber bumper, fog lights, chrome rocker moldings, bright fender vent trim, a color-keyed grille, and factory Flat Black "Hemi" billboards adorn the car's exterior, while a black interior is equipped with leather high-back leather bucket seats, a three-spoke Rimblow steering wheel, center console with Hurst Pistol Grip shifter, a full Rallye instrument cluster (including a 150mph speedometer and 8,000rpm tachometer), pushbutton radio, and power windows. Power steering and front disc brakes make the 'Cuda much more fun to drive – though it has only seen 33,000 miles of blacktop, and color-matching steel wheels with dog-dish caps wrapped in fifteen-inch Goodyear Polyglas tires mean the buyer will be cruising in style.
The '71 Hemi 'Cuda comes with two colored factory broadcast sheets, two fender tags, and Chrysler registry Galen Govier documentation.
To bid on this fine 'Cuda and to learn more, visit www.mecum.com.


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Kansas to pursue prairie chicken breeding program
TOPEKA, Kan. (AP) — Kansas will develop a program for breeding lesser prairie chickens in hopes of getting the federal government to back off its listing of the bird as a threatened species, Gov. Sam Brownback announced Thursday.
An Audubon of Kansas leader labeled the idea "far-fetched" and said it won't work because game birds bred in captivity typically don't have the skills necessary to survive long in the wild.
Brownback, a Republican and a strong critic of the U.S. Fish and Wildlife's decision to list the bird as threatened, said he directed the Kansas Department of Agriculture and the Department of Wildlife, Parks and Tourism to draft a plan for such a program. Brownback spokeswoman Eileen Hawley said the program would round up prairie chickens in the wild, have them mate in captivity and then release them.
The bird's listing as threatened means the federal government has oversight of state preservation efforts. It affects Kansas as well as four other states with prairie chicken habitats — Colorado, New Mexico, Oklahoma and Texas.
Kansas has taken multiple steps to challenge the listing. Brownback and other officials contend it will damage the economy because farmers, ranchers and oil and natural gas producers face restrictions on their operations and potentially hefty conservation fees. The federal agency said in March the listing was justified by a decline of nearly 50 percent in the lesser prairie chicken's population between 2012 and 2013.
The federal government must sign off on a captive breeding program for the bird, and Brownback said the state will seek the required permit.
"We know there will be challenges to this program, but I believe it is worth the effort to restore the chicken's population and get this federal regulatory burden off the backs of hard-working Kansans," Brownback said in a statement.
U.S. Fish and Wildlife Service spokeswoman Lesli Gray said the agency couldn't comment on Brownback's plan because he just announced it, but the agency would review any request for a permit.
"Obviously, the Fish and Wildlife Service is interested in working with any parties on conservation efforts," Gray said.
But Audubon of Kansas Executive Director Ron Klataske said he doesn't see the federal government signing off on a captive breeding program, which he said are generally used now to breed game birds — raising them until they can fly for release into hunting areas to be downed within hours.
"Wildlife agencies have abandoned that approach, decades ago," Klataske said. "I can't imagine that any qualified biologist would endorse this."
Hawley said the program would be similar to one for the Attwater's prairie chicken, an endangered cousin to the larger and darker greater prairie chicken found in coastal grasslands in Texas. But Klataske called that program "an incredibly expensive" attempt at "propping up" a species near extinction.
Kansas officials have said repeatedly that persistent drought caused the decline in the lesser prairie chicken's population, and its numbers would rebound with adequate rain.
The Western Association of Fish and Wildlife Agencies said last week that an aerial survey showed good rains in parts of the animal's five-state range led to a 20 percent increase in its population from last year. The association said there were about 22,400 birds, up from fewer than 18,800 last year.
Follow John Hanna on Twitter at https://twitter.com/apjdhanna .
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Sell Your Home in San Diego County | Full Service
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Additional Details About 5663 Chelsea Ave, La Jolla CA 92037
The property address for this home is 5663 Chelsea Ave, La Jolla CA 92037. It is listed in the San Diego MLS under MLS # 180067806.
This home features three bedrooms, three baths, is 2971 square feet and has a list price of $3,295,000.00. This home is located in the city of La Jolla in the 92037 code. It is located in the community of La Jolla.
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If you want to only view homes for sale in the 92037 zip code you can view all of those homes for sale here. If you would like to view more information about what it is like to live in the La Jolla please visit our La Jolla page for additional information.
This property's price per square foot is $1,109.05.
The details below will provide you photos of 5663 Chelsea Ave, La Jolla CA 92037, you can also view the google map location and street view location for this home located in La Jolla.
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Name: Malena Suarez
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You know, I was worried about Kyle Farnsworth after getting hit by that ball. It really sounds crazy, but this is exactly how I felt and I am not going to lie about it. I said this before and I will say this again. We will never find out who is the Joba's replacement if Joba is still in the bullpen. Without questions, we all know how important the decision is to move Joba into the starting rotation, especially after Wang's injury.
I start realizing we use Mo's standard to judge Kyle Farnsworth. It's not fair. We need every arm we can get to help out our bullpen, especially when you consider we lose Wang who is inning eater.
By the way, Andy is the man, right? Sometimes you just feel more comfort when you see someone on the mound. Andy is one of them on my list. Of course, Mo sits on top of my list. I just never feel nervous when they are on the mound. How cool it is if Mo wins Cy Young Award and Moose finally has his 20 wins season?
I actually feel fine Yankees finish 4-2 during this homestand. We are not going to win every game as long as we keep winning most of series.
Monday, June 23, 2008
I can't believe what I just said...
Posted by: Jessica Lee at 6:50 PM
2 comments:
- Todd Drew said...
Kyle Farnsworth has helped us win a bunch of games this year and he will help us win a bunch more before it's over. His control has been good and he's really pitching well. A couple of solo home runs when we have big leads isn't the end of the world.
He's also tough and I don't think a few stitches will keep him down long, which is good because we need him.
- June 24, 2008 at 3:57 AM
- Jessica Lee said...
If Kyle saw what we just said, he won't be upset about Yankees fans at all.
- June 24, 2008 at 9:30 AM
Subscribe to: Post Comments (Atom)


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Dwight McNeill Joins Healthcare Faculty
Beginning this fall, Dwight McNeill will be teaching HLTH 828: Population Health, a course that provides fundamental epidemiology and public health principles and analytic techniques that help professionals plan, deliver, and evaluate health services. "Population health stretches the boundaries of traditional healthcare and fosters a systems approach to solving problems and achieving health outcomes," McNeill explained.
McNeill, who has a PhD in Health and Social Policy, as well as an MPH in Epidemiology and Public Health, specializes in advanced analytics, performance measurement, systems and payment reform, community accountability, and people-centered healthcare.
He is looking forward to teaching after spending most of his career working in business, government, and healthcare organizations. "I want to get back to teaching, writing, and 'systems thinking,' he said, adding that he enjoys having an "active interchange with students."
McNeill is currently the president of WayPoint Health Analytics, a consulting practice that provides education, research, and guidance to on how organizations can use analytics to enhance business decision-making, engage patients, and improve the financing and delivery of healthcare. He is also a guest lecturer at Duke University Fuqua School of Business and lead faculty for the healthcare industry at the International Institute for Analytics.
McNeill has extensive experience working in corporate settings, most recently as the global leader for business analytics and optimization for the healthcare industry for the IBM Corporation, and previously as director of healthcare information at GTE Corporation (Verizon).
As the former assistant commissioner for Health Data and Analytics for the Division of Health Care Finance and Health Policy of the Department of Health and Human Services, McNeill helped bring an analytics focus to healthcare reform in Massachusetts.
At the Agency for Healthcare Research and Quality, McNeill helped translate research to action and promoted the importance of performance measurement and national priorities at the National Quality Forum.
He hopes his experiences will offer his students unique insight and inspire them to learn on their own. To illustrate his point, McNeill quoted William Hazlitt: "You know more of a road by having traveled it than by all the conjectures and descriptions in the world."
McNeill has published numerous articles in Health Affairs and other prestigious journals. He is currently working on a book, titled Transforming Healthcare through Analytics: What can be Learned from the Best Practices in Retail, Banking, Politics, Military, and Sports, which is scheduled for publication in early 2013.
Peter Rivard, assistant professor of Healthcare Administration, has worked with McNeill to update and prepare the Population Health course for its fall 2012 offering. According to Rivard, "Dwight is a real find for our healthcare programs and for the Population Health course. Given his background, he has a deep understanding of both the business of healthcare and the potential of the rapidly evolving field of population health analytics to transform how that business is managed. He is an engaging personality; his curiosity is infectious; he has a knack for explaining complex ideas clearly; and he promises to be an outstanding teacher."


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Kyocera Loft Data Cables
You came to the right place for the Kyocera Loft. Accessory Wiz offers the most competitive prices for Kyocera Loft accessories such as handsfree headphones, cases, pouches, home wall chargers, cell phone car chargers, stereo and mono headsets, armbands and more cell phone accessories. Its stylish design, new features and user friendly menu are making the brand new Kyocera Loft popular in the market. The dimensions of Kyocera Loft are 4.06 x 2.60 x 0.57. Accessory Wiz is always making the best efforts to bring the latest and high quality cell phone accessories.


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Lights dim for one of the Harbaughs
NEW ORLEANS — Jim Harbaugh wanted a hold, and he gestured on the sideline for it with his usual fury.
Afterward, he didn't want a hug, opting instead for a quick handshake with his brother. That's him.
But he also wasn't himself at the end. With first-and-goal, with time to unleash either his extraordinary quarterback or lean on his offensive line, he was neither daring nor aggressive.
So give the older brother the Lombardi Trophy.
And the younger brother the blame.
Give Ray Lewis and his teammates considerable credit, too, because they were rugged when they needed to be. The Baltimore red-zone defense ended the first half by holding the 49ers to just a field goal and ended the game by holding the 49ers to nothing.
Also give Lewis a better sense of NFL spirituality. "It's simple," he said afterward. "When God is for you, who can be against you?"
The 49ers, heathens that they are, only had Vegas on their side.
If anything looked down from above with impact on this game, it was a bank of lights. That came after the Ravens took control of the game early.
One first-half stat said how much: Justin Tucker, the Texas product turned Baltimore kicker, had as many rushing yards in the first half as Colin Kaepernick.
And after Jacoby Jones, the former Houston Texan, returned a kickoff almost as long as the game allows? The 49ers looked finished down 28-6.
But then came the karma moment, with rich people this time caught inside the Superdome. Power went out for 34 minutes, and, suddenly, John Harbaugh was the animated brother.
He knew. Delays can change things.
One did two years ago, and the NFL should be warned. This one happened in the venue where the Super Bowl will be next season.
Then, in November of 2010 at MetLife Stadium, the Giants were driving in a tight game. The power failed then, too, and the stoppage in play allowed the Cowboys to gather themselves. That, in part, is how Jason Garrett won his first game as the Dallas coach.
This delay had a similar effect, with the 49ers going on a 17-0 run. "It flipped the momentum," John said, and Lewis likely had an explanation for that, too.
Wasn't it the work of the devil?
The 49ers didn't do much at first. But the next time they had the ball, after Joe Flacco finally stopped being Joe Montana for just a moment, Kaepernick showed off his arm and Michael Crabtree his muscle.
Later, Kaepernick sprinted in for another touchdown, complete with the kiss of a biceps. And after Flacco answered by driving the Ravens down the field to set up a field goal, here came Kaepernick again.
He picked up a first down with a scramble, then found Crabtree over the middle for 24 yards. Frank Gore followed with a burst that nearly resulted in a touchdown, and there the 49ers were, with more than two minutes left, just 7 yards from the lead.
What came next was a series Jim Harbaugh will relive for a career.
With purpose or reason, the 49ers went away from Gore, as well as from the pistol. The 49ers became passive and reactionary, which is not how the younger brother has lived his life.
The fourth down play summed it up. Then, again failing to respond to a Ravens blitz, Kaepernick was forced to throw quickly. It was a weak fade. And while there was contact, and maybe enough for a penalty, Harbaugh was desperate to ask for it.
"Who's got it better than us?" Jim loved to ask his team this season.
"They do," was the appropriate response this time.
Twitter: @Buck_SA


text: Founded in 1884 by Swiss apprentice knife-maker Karl Elsener, Victorinox is a brand steeped in heritage. Elsener created the first Swiss Army Knife model after opening a cutlery workshop with the aim of providing the Swiss army with a soldier knife. Today, the label has expanded and evolved into a range of travel gear, hardwearing luggage and stylish watches designed with the same functional simplicity. Men's Victorinox luggage is the ultimate travel companion for the modern man. These wheeled suitcases, cases and duffel bags offer superior functionality while looking supremely stylish.


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Spend Your Life Living
Tomorrow is important, but life is happening today.
We don't think you should spend your life in 2019 waiting to live. You should spend it living.
We'll evaluate where you are and where you want to go. Then, We'll work with you on a personalized financial plan that will help you reach your goals with the right mix of Northwestern Mutual insurance products and investment strategies.
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Northwestern Mutual - Spend Your Life Living


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Damask Monogrammed Mousepad
Looking to spruce up your desk at home or at work? Personalized mouse pads are the answer! Co-workers, teachers & friends love monogrammed mouse pads.
Each measures about about 9x8" and a 1/4" thick with a fabric top and black rubber bottom
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Brain chemicals help worms live long and prosper
Serotonin and dopamine accompany life span extension in nematodes on a diet
Kbradnam/Wikimedia Commons
The fabled elixir of life delivers eternal youth free from the bodily indignities that come with age. In reality, worms on a restricted diet also live long, healthy lives, thanks to high levels of certain neural chemicals, a new study suggests.
Unlike their normal counterparts, worms on a diet maintain high levels of serotonin and dopamine as they get older, scientists report in the March 12 Journal of Neuroscience. But calorie restriction wasn't necessary to get some benefits: Extra serotonin on its own seemed to provide behavioral improvements and a modest life span boost.
It's too early to say whether the results hold true for other animals, but there are hints that the brain's serotonin and dopamine machinery goes awry in people as the years advance.
The worm results may help clarify which physiological changes can actually influence the aging process and which are just


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Features of the GeneMapper® ID-X Software
GeneMapper® ID-X implements functionality and features to support Expert System data analysis and increase the efficiency of traditional (manual) data analysis.
Included in the system are the following features:
- Analysis Requirement Check
- Allelic Ladder Quality Assessment
- Analysis Summary
- Comprehensive Quality Value System
- Quality Value Flags
- Manual Review Tools
- Color-Coded Marker Header Bars
- Labeling Scheme
- Label Edit Viewer
- Mixture Analysis Tool Features
- Quality Control
- Report Manager
- Multi-User Database Environment
- Chain-of-Custody Features
- Command Line Interface
Analysis Requirement Check
The analysis requirement check identifies unmet requirements before analysis starts and can be set up to stop analysis and display an alert if a specific sample type is not found.
Allelic Ladder Quality Assessment
The allelic ladder quality assessment evaluates allelic ladders before proceeding to sample analysis and automatically excludes low-quality ladders. There is an option to override the software assessment to use low-quality ladders to generate bin offsets.
Analysis Summary
For efficient data evaluation, the analysis summary provides easy-to-view summary of analysis results, an overview of allelic ladder, control and sample quality, and interactive links to specific categories of samples.
Comprehensive Quality Value System
GeneMapper® ID-X incorporates a comprehensive quality value system which enables it to be used as an Expert System. The quality value system:
- Assesses the quality of allelic ladders before analysis and does not consider low-quality allelic ladders for genotyping.
- Assesses the quality of data at the sample and marker level using process quality values (PQVs). Some of these include:
- Sizing quality
- Off-scale peak detection
- Spike detection
- Evaluation of the number of alleles
- Minimum and maximum peak height
- Peak height ratio
- Broad peak detection
- Composite genotype quality (overall sample quality)
- Off-ladder allele detection
- Can be used to segregate samples that require manual review from those that do not
- Can be used by analysts to quickly identify quality issues and aid in data interpretation
- Incorporates automated concordance checks for positive and negative controls
- The ability to manually accept marker and sample genotypes
The PQV results of the quality assessment are displayed as color-coded flags:
The color of the flag depends on software-specified thresholds or user-defined thresholds.
Quality Value Flags
Quality value flags are the first review tool the analyst can use. This tool gives you an indication of the quality of the entire sample by identifying and interpreting anomalies within the data.
Manual Review Tools
For efficient data review in traditional manual review and expert systems workflows, the manual review tools provide:
- Process quality value (PQV) flags
- Automatic spike labeling based on intelligent rules
- User-defined "artifact" peak labels
- Marker-specific quality value details with thresholds and observed values displayed to show deviations from thresholds and identify sources of anomalies
- Mark Sample for Deletion and Delete All Labels from Sample functions in the Samples plot to allow easy elimination of low-quality samples directly from the plot window
- Override GQ and CGQ functions to "manually accept" genotypes at the marker and sample level
- Detailed label edit table display and visual indicators to indicate edits (gray PQVs) for electronic peer/technical review
Color-Coded Marker Header Bars
The marker header bars are now colored (green, yellow, or red) helping analysts quickly identify problem areas and determine the cause.
Labeling Scheme
A new and more sophisticated labeling scheme has been introduced to improve the editing options available to the analyst. The software automatically labels spikes based on intelligent rules and provides the ability to assign "artifact" peak labels which do not get placed in the genotypes table. This feature saves time for analysts who normally manually change the labels.
Label Edit Viewer
The label edit viewer provides the analyst a detailed list of all allele edits and comments made within the project or for a selected group of samples.
Mixture Analysis Tool Features
GeneMapper® ID-X Software v1.1 and v1.2 provides an integrated Mixture Analysis Tool to assist forensic analysts with mixture interpretation. The Mixture Analysis tool features:
- Segregate samples by minimum number of contributors
- Extract 2-person mixtures based on mixture proportion and peak height ratios
- Display a ranked set of possible genotype combinations to minimize the number of genotypes necessary to interpret
- Choose to designate a known contributor to aid in extraction if desired
- Calculate statistics including Random Match Probability (RMP), Combined Probability of Inclusion/Exclusion (CPI/CPE) and Likelihood Ratio (LR)
Quality Control
The Profile Comparison Tool allows the user to perform QC/QA checks on the data contained within a project and evaluate efficiently any potential contamination events. The profile Comparison tool allows the analyst to perform the following:
- Evaluate sample concordance and allele matching
- Include additional custom positive controls and allow automatic concordance checks of custom controls
- Compare samples in a project to one another to determine if they contain profiles similar to neighboring samples
- Compare samples in a project to laboratory reference and custom control profiles using a user-defined match percent threshold
Report Manager
For customized table-formatted reports, the Report Manager allows the analyst to change column names and column order and export a traditional horizontal allele table for a selected group of samples for use as a genotype summary or import into LIMS or other downstream applications.
Multi-User Database Environment
The multi-user database environment:
- Allows multiple users to share projects in a centralized database
- Facilitates efficient data sharing between analysts for second analysis and review
- Limits the need to import and export projects
- Allows central management of analysis settings
Chain-of-Custody Features
Electronic data chain-of-custody features allow controlled user access to software and data, auditing and reporting of some or all analyst actions, the option of a requirement for user-authentication before saving a change and custom configuration to meet the data management needs of each laboratory.
Command Line Interface
Enables streamlined integration with LIMS or other external software applications.


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A judge still must sign off on the agreement between the actor and Cedars-Sinai Medical Center
Dennis Quaid and his wife Kimberly have reached a settlement of $750,000 against Cedars-Sinai Medical Center for the accidental overdose of their newborn twins in 2007.
The agreement is pending the approval of a Los Angeles judge.
"The settlement is the result of extensive negotiations between the parties and their respective legal representatives, and is intended to avoid the time, expense and uncertainty of litigation," say papers filed in L.A. Superior Court on Monday.
An attorney for Quaid declined to comment.
Just two weeks after twins Thomas Boone and Zoe Grace were born in November 2007 via gestational carrier, they were accidentally given a massive overdose of the blood thinner Heparin, and spent days battling for their lives.
The babies recovered and are now in good health, providing what Quaid, 54, called a "happy ending" to the medical scare.
Cedars-Sinai has been fined $25,000 by the California Department of Public Health. A hospital spokesman said the facility cooperated with state authorities and intended to pay the fine. The hospital has since apologized to the patients' families and said it has taken steps to better train the staff.
The Quaids have also filed a lawsuit against Heparin's drug maker, Baxter Healthcare Corp., accusing it of negligence in packaging adult and pediatric doses in similar vials. The settlement with Cedars does not affect that lawsuit.
• What's your opinion on the lawsuit? Leave your comments here
• 2007: Dennis' twins fight for their lives after a hospital error


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It has a warm-up time of only 5 minutes and has a huge output capacity. We ran the FG-1300 through a battery of testing sessions and were extremely impressed with the results every time.
Do you own this product? Write a review.


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(Reuters) - Abenomics has a critical weakness: Japan's companies are not playing along and it's hard to blame them.
Japan's economy, struggling to end decades of deflation and recession, grew at a disappointing 2.6 percent annualized clip in the second quarter, according to figures released on Monday, a full percentage point below forecasts and a marked slowing from the first three months of the year.
While the poor showing immediately focused minds on whether the economy could withstand a planned hike in sales tax, the real puzzle lies in the story behind yet another fall in investment by companies.
So-called capital expenditure fell by 0.1 percent in the quarter, frustrating predictions of the first gain in almost two years. That's critical because an unwillingness by Japanese companies to invest and to hire is acting as a circuit breaker on Abenomics, effectively blunting the transmission of monetary and fiscal policy to the real economy.
Abenomics, a cocktail of fiscal and economics stimulus poured over a base of reforms, is intended, among other things, to drive down the value of the yen, which in turn should allow newly competitive companies to export more, hire more workers and contribute to a virtuous cycle of investment, consumption and growth.
The yen part has worked perfectly, with the currency falling about 20 percent against the dollar in the past year.
That has certainly been a boon for Japanese companies, many of which have seen profits double. High profits have not translated into investment and growth however, despite reasonable demand for Japanese products globally.
Perhaps even worse, recent surveys of purchasing managers point to a worse outlook for the coming months.
"Worryingly, PMI data also showed companies cutting headcount again after two months of job creation, reflecting growing uncertainty about the economic outlook," according to Chris Williamson, chief economist of Markit, whose combined manufacturing and services barometer fell to 50.7 in July, just above the 50 reading which divides contraction from growth.
So why aren't companies playing their part? Because they don't have to, for one thing. While the yen means companies could cut prices to expand market share, they have another quite attractive option: simply keep prices competitive on exports but, rather than expand market share, allow profit margins to expand. That is especially attractive given all the uncertainty in Japan's outlook. The weak yen is by no means permanent and many factors might mean that investments made in Japan now don't pay off.
For one thing, Japan's quadrillion-yen debt (yes, that's right, public debt passed 1,000 trillion, or a quadrillion, yen in June, equal to 200 percent of GDP) might force it to raise sales taxes as planned. That in turn would crimp domestic demand, with about a third of economists forecasting a recession if the sales tax rises from 5 to 8 percent next April as proposed.
So far, the behavior, as opposed to the rhetoric, of major Japanese exporters shows a tendency to book profits and play conservatively.
Toyota almost doubled its net profits in the second quarter even though it sold fewer cars. And while Nissan bumped U.S. sales of cars by a fifth after it cut prices, Ford, GM and Chrysler all gained market share in their home market so far this year.
In other industries profits are improving, as are exports, but it mostly seems to be a demand story rather than a result of the newly weak yen. To be sure, investment is a long process, and Japanese companies are not known for making lightning-fast decisions about significant expansions. It may well still turn out, should the yen remain weak and should the domestic economy seem stable, that Japanese companies in the end do come through with investment, improving the outlook perhaps for 2014 and beyond.
Interestingly, the phenomenon of just sitting back and enjoying fat margins without making new investment probably has a different cause in Japan than in other places, like Britain. While when the pound dropped in 2008, British companies "priced to market," simply allowing fat profits to roll in. That was likely driven in part by compensation practices in Britain, which tie executive pay closely to stock market movements through share options. British CEOs, faced with the option of a gratifying short-term bump in the value of their shares versus a risky long-term investment in more production, usually chose to take the money now.
In Japan, executive pay practices are significantly different, making low investment more likely to be the result of risk analysis colored by the very difficult experience anyone managing a big company in Japan has had these past 20 years.
While there are a quadrillion reasons Abenomics may not work, the weight of history only adds to the count.
(James Saft is a Reuters columnist. The opinions expressed are his own)
At the time of publication, Reuters columnist James Saft did not own any direct investments in securities mentioned in this article. He may be an owner indirectly as an investor in a fund. For previous columns by James Saft, click on


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Laennec's stethoscope, France, 1815-1825
As a medical practitioner, how can you find out about what is going on inside a patient's body? Especially when many causes and symptoms of disease are not immediately obvious. For a long time you would have had to be content simply to observe any outward signs of disease, such as skin colouration or pulse, or to investigate excretions of the patient's body, such as urine or faeces. Since the 1800s, however, you would have had another option – the stethoscope, an instrument to help you listen to the sounds of the patient's body. The French physician René Théophile Laennec (1781-1826) invented the stethoscope in 1816 after being consulted by a young female patient with heart problems. Subject to the social conventions of the day, Laennec considered it improper to listen to the sounds of her heart by putting his head directly on her chest. Instead, he rolled up a piece of paper into a tube and placed one end on the patient's chest and the other at his own ear. The tube communicated the sounds of the heart and helped Laennec diagnose the patient's condition. He subsequently developed a robust wooden tube to replace the makeshift paper one and called it a stethoscope – from the Greek words for "chest" and "explore". This is one of the original stethoscopes belonging to him. Made of wood and brass, it is a single hollow tube. The familiar binaural stethoscope, with rubber tubing going to both ears, was not developed until the 1850s. With such amplified sounds, diseases of the lungs, heart and vascular systems could be diagnosed much more easily and reliably.
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Glossary: monaural stethoscope
An instrument used to listen to sounds produced by the human body.
Glossary: stethoscope
A device which is used to listen to sounds produced by the human body. Ordinarily a stethoscope consists of rubber tubing in the shape of a Y.
Glossary: percussion
Practice where a doctor taps on parts of the patient's body with his fingers or an instrument called a plessor. The resulting sounds and vibrations reveal the presence of fluid or tissue that has hardened.


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Are you lucky enough to have a dirty cake shop in your neighbourhood?
See here the coffer of flowers with the march of the dinosaurs bringing up the rear.
We at Lush Designs have several to choose from. This is our favourite, not because the cakes are the dirtiest - why, there aren't any flies or even cobwebs visible. No it is the combination of obvious great age (note the bleached out and grisly colours) with the charmingly frivolous designs.
Miss Havisham, eat your heart out (or at least chow down on the grey heart-shaped glory, top right)
Virgin brides and drooping beige ribbons
Gambling on love


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It seems like Texas Sen. Ted Cruz had a touch of the big government blues this morning.
Cruz went on a bit of a Twitter rant this morning, sending out tweets saying that the government has become too large to be efficient, like this one:
Whether it's #IRS, #NSA, #Benghazi, or #Obamacare, one thing is clear. Fed govt is too big, too powerful, and too unaccountable.
— Senator Ted Cruz (@SenTedCruz) June 10, 2013
Just one minute later, Cruz was at it again with this post:
We must drastically reduce the size and scope of the government's influence in our lives.
— Senator Ted Cruz (@SenTedCruz) June 10, 2013
Like many of Cruz's tweets, these two produced hundreds of retweets, favorites and responses, some of which urged him to run for president in the 2016 election.
Though Cruz is a freshman senator, his name has been tossed around quite a bit over the last few weeks in 2016 presidential speculation.
Cruz has made himself into a prominent voice in recent weeks on various hot topics, such as immigration reform and the recent IRS scandal, speaking out both on Twitter and Capitol Hill.
In March, Arizona Sen. John McCain described Cruz as a "wacko bird" when it came to how outspoken they were on The Hill. McCain later apologized for this statement, but Cruz has recently adopted the term as his own.
"If standing for liberty, if standing for free market principle and the Constitution makes you a wacko bird, then, then I am a very proud wacko bird," he said on Fox Business last weekend.
When asked what he stood on running in the upcoming presidential election, Cruz answered, "The U.S. Senate is the battlefield right now."
Emphasis on "right now."
Though Cruz hasn't hinted of any plans to run in 2016, he hasn't ruled out the notion either.
Cruz has agreed to attend numerous events that are often seen as early steps in a presidential campaign for prominent Republicans considering running for office.
The Iowa Republican Party will host Cruz at an annual picnic on July 19, at which attendees can donate $100 and join the senator for lunch. For $500, a photo-op is included. That same weekend, Cruz is expected to attend another Iowa gathering, David Lane's "Pastors and Pews" event, at which Cruz is to deliver the keynote address.
As Iowa is home to the first caucus of election season, both stops could provide crucial early campaign coverage and connections for Cruz as 2016 continues to approach.


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HFK Vs. 3rdPerson Rap Battle [KOTD - Canada Edition]
KOTD KingOfTheDot King Of The Dot "PutYourMoneyWhereYourMouthIz" Toronto Edition Vol 4 Judges: Soze, Adam Bomb, Camoflauge Hosted By: Organik
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'Modern Family' Cast Members to Host 2012 Billboard Music Awards
The 2012 installment of the Billboard Music Awards have selected Emmy-winning tv stars Julie Bowen and Ty Burrell of 'Modern Family' to host the awards ceremony, which airs live from Las Vegas on Sunday, May 20 at 8PM ET on ABC.
"We are thrilled to have television's favorite Emmy Award-winning couple as our hosts for this year's Billboard Music Awards," said Prometheus Global Media CEO Richard D. Beckman in a statement. "Ty and Julie have captured the hearts of America with their on-screen chemistry and humor — and we look forward to having them bring that magic to the Billboard Music Awards."
In 2011, the Billboard Music Awards returned from a 4-year hiatus with 'Community' actor Ken Jeong as host. Eminem and Justin Bieber each nabbed six awards. This year, Adele leads the pack as a finalist in a whopping 18 categories. LMFAO are up for 17 awards, and Rihanna has 13 nominations.
Bieber, LMFAO, the Wanted and Carrie Underwood have already signed on as performers for the 2012 shindig, with many more acts still to be announced. The nominees for Top Artist are Adele, Lady Gaga, Lil Wayne, Katy Perry, and Rihanna.


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The Liege Acromegaly Survey (LAS) : A new software tool for the study of acromegaly
PETROSSIANS, Patrick ; ; Stevenaert, Achille et al
in Annales d'Endocrinologie (2012), 73Detailed reference viewed: 68 (14 ULiège)
Does radiation treatment delay affect survival in glioblastoma
Robe, Pierre ; Nguyen-Khac, Minh-Tuan ; Lenelle, Jacques et al
in Surgical Neurology (2009), 72(5), 519Detailed reference viewed: 94 (15 ULiège)
Does radiation treatment delay affect survival in glioblastoma ?
Robe, Pierre ; Nguyen Khac, Minh-Tuan ; Lenelle, Jacques et al
Conference (2009, March 21)Detailed reference viewed: 55 (13 ULiège)
Cushing disease : Influence of microsurgery on hormonal balance
Vroonen, Laurent ; Martin, Didier ; Valdes Socin, Hernan Gonzalo et al
in European Neuroendocrine Association - Workshop : Novel insights in the management of Cushing's syndrome (2009)Detailed reference viewed: 26 (5 ULiège)
Cushing disease : Pituitary microsurgery on hormonal balance
Stevenaert, Achille ; Vroonen, Laurent ; et al
in European Neuroendocrine Association - Workshop : Novel insights in the management of Cushing's syndrome (2009)Detailed reference viewed: 22 (1 ULiège)
Long-term follow-up reveals low toxicity of radiosurgery for vestibular schwannoma
; ; Seidel, Laurence et al
in Radiotherapy and Oncology (2007), 82(1), 83-89
AIM: The long-term effects of radiosurgery of vestibular schwannomas were investigated in a group of consecutively treated patients. METHODS AND MATERIALS: Between 1995 and 2001, 26 patients (median age ... [more ▼]
AIM: The long-term effects of radiosurgery of vestibular schwannomas were investigated in a group of consecutively treated patients. METHODS AND MATERIALS: Between 1995 and 2001, 26 patients (median age: 67, range: 30-82) with a vestibular schwannoma were treated by Linac-based stereotactic radiosurgery (SRS). The median follow-up was 49 months (16-85 months). Only progressive tumours were treated. The median size of tumours was 18 mm (range 9-30 mm). Before SRS, 11 patients had a useful hearing (Gardner-Robertson classes 1 and 2). Single doses of 10-14 Gy were prescribed at the 80% isodose at the tumour margin. The follow-up consisted of regular imaging with MRI the first 3-6 months after the intervention, followed by additional yearly MRIs, a hearing test and a neurological examination. RESULT: The 5-year-probability of tumour control (defined as stabilization or decrease in size) was 95%. Five-year-probability of preservation of hearing and facial nerve function was 96% and 100%, respectively. Hearing was preserved in 10 out of 11 patients who had a normal or useful hearing at the time of treatment. Mild and transient trigeminal toxicity occurred in 2 (8%) patients. It appeared to be significantly correlated to the dose used (p=0.044). However, only a tendency to significance could be demonstrated in the relationship between the two factors when using the Cox analysis (hazard ratio=1.7; 95% CI: 0.7-3.9; p=0.23). CONCLUSIONS: With the doses used, our study demonstrates that SRS provides an equivalent tumour control rate when compared to surgery, as well as on a long-term basis, an excellent preservation of the facial and the acoustic nerves. Although no permanent trigeminal toxicity was observed, our data confirm that doses below 14 Gy can avoid transient dysesthesias. [less ▲]Detailed reference viewed: 78 (3 ULiège)
Classical pituitary tumour apoplexy: clinical features, management and outcomes in a series of 24 patients.
Dubuisson, Annie ; Beckers, Albert ; Stevenaert, Achille
in Clinical Neurology and Neurosurgery (2007), 109(1), 63-70
We retrospectively analysed the incidence, clinical presentation, endocrinological and radiological findings, medical and surgical management of pituitary apoplexy in our department (single-centre study ... [more ▼]
We retrospectively analysed the incidence, clinical presentation, endocrinological and radiological findings, medical and surgical management of pituitary apoplexy in our department (single-centre study), having a large experience in pituitary surgery. Among 1540 pituitary lesions, 24 patients presented with pituitary apoplexy. Their charts were retrospectively reviewed. The symptoms included headache (92%), nausea and vomiting (54%), visual deficit (50%), oculomotor paresis (54%) and/or an altered mental state (42%). Skull X-rays (n = 14) demonstrated an enlarged sella turcica in all cases; CT-scan and/or MRI always revealed a sellar and suprasellar expanding lesion. Panhypopituitarism was present on admission in 70% of the patients. Urgent therapeutic management included high-dose cortisone treatment in all but one patients and CSF drainage in three. Three patients were treated conservatively. Nine patients were operated on rapidly, within hours or a few days because of severe visual deficit and/or altered level of consciousness. Nineteen patients were operated by the trans-sphenoidal approach; one of them required a second operation by craniotomy. There were two deaths related to the illness and one to an ill-defined reason at 4 months. Among the other patients 95% made a good recovery. All but two patients required a substitutive treatment with adrenal (83%), thyroid (68%), gonadal (42%) and/or growth (16%) hormones. The preoperative visual deficits recovered in all but one patients (92%) whereas the oculomotor pareses improved in all but two patients (85%). In conclusion, pituitary tumour apoplexy is a rare event, complicating in our series 1.6% of 1540 pituitary adenomas. Even in severe cases, complete recovery is possible if the diagnosis is rapidly obtained and adequate management is initiated in time. Surgical results after trans-sphenoidal approach are in the majority of cases very satisfactory. [less ▲]Detailed reference viewed: 39 (4 ULiège)
Intrasellar arachnoid cysts.
Dubuisson, Annie ; Stevenaert, Achille ; Martin, Didier et al
in Neurosurgery (2007), 61(3), 505-13513
OBJECTIVE: To evaluate the clinical, endocrinological, and radiological presentation of nine cases of surgically verified intrasellar arachnoid cysts and to discuss the physiopathological mechanisms of ... [more ▼]
OBJECTIVE: To evaluate the clinical, endocrinological, and radiological presentation of nine cases of surgically verified intrasellar arachnoid cysts and to discuss the physiopathological mechanisms of formation of these cysts. METHODS: Among 1540 patients presenting with pituitary lesions, nine presented with an intrasellar arachnoid cyst. Their charts were retrospectively reviewed. RESULTS: Presenting symptoms included headache (n = 2), visual symptoms (n = 3), menstrual irregularities (n = 2), rapid weight gain (n = 1), vertigo (n = 1), and/or confusion (n = 1). Two cysts were discovered incidentally. T1-weighted magnetic resonance imaging scans showed an intrasellar cystic lesion in all cases, with a huge suprasellar extension in six cases. The cyst was of the same intensity as the cerebrospinal fluid (CSF) in only two patients. A transsphenoidal approach allowed the transdural aspiration of fluid and injection of a water-soluble contrast agent under mild pressure. In three patients, the contrast infiltrated along the pituitary stalk toward the subarachnoid spaces; in the other patients, it remained in the intrasellar compartment. Cyst membranes were removed as completely as possible with fenestration toward the subarachnoid spaces in communicating cysts. In spite of tight packing of the sella and sphenoid sinus, CSF fistulae requiring reoperation developed in two patients. CONCLUSION: The clinical picture of an intrasellar arachnoid cyst resembles that of a nonfunctional pituitary adenoma. Magnetic resonance imaging scans typically show a cystic intrasellar lesion with suprasellar extension, containing isointense or, more often, hyperintense fluid on T1-weighted sequences. In spite of the risk of CSF fistulae, the preferred surgical approach is transsphenoidal. A physiopathological mechanism is proposed according to anatomic variations of the sellar diaphragma allowing penetration of subarachnoid spaces into the sellar compartment and their enlargement by a ball-valve mechanism. [less ▲]Detailed reference viewed: 63 (5 ULiège)
Clinical characterization of familial isolated pituitary adenomas.
Daly, Adrian ; ; et al
in Journal of Clinical Endocrinology and Metabolism (2006), 91(9), 3316-23
CONTEXT: Familial pituitary adenomas occur rarely in the absence of multiple endocrine neoplasia type 1 (MEN1) and Carney complex (CNC). OBJECTIVE: Our objective was to characterize the clinical and ... [more ▼]
CONTEXT: Familial pituitary adenomas occur rarely in the absence of multiple endocrine neoplasia type 1 (MEN1) and Carney complex (CNC). OBJECTIVE: Our objective was to characterize the clinical and genealogical features of non-MEN1/CNC familial isolated pituitary adenomas (FIPA). DESIGN AND SETTING: We conducted a retrospective study of clinical and genealogical characteristics of FIPA cases and performed a comparison with a sporadic population at 22 university hospitals in Belgium, Italy, France, and The Netherlands. RESULTS: Sixty-four FIPA families including 138 affected individuals were identified [55 prolactinomas, 47 somatotropinomas, 28 nonsecreting adenomas (NS), and eight ACTH-secreting tumors]. Cases were MEN1/PRKAR1A-mutation negative. First-degree relationships predominated (75.6%) among affected individuals. A single tumor phenotype occurred in 30 families (homogeneous), and heterogeneous phenotypes occurred in 34 families. FIPA cases were younger at diagnosis than sporadic cases (P = 0.015); tumors were diagnosed earlier in the first vs. the second generation of multigenerational families. Macroadenomas were more frequent in heterogeneous vs. homogeneous FIPA families (P = 0.036). Prolactinomas from heterogeneous families were larger and had more frequent suprasellar extension (P = 0.004) than sporadic cases. Somatotropinomas occurred as isolated familial somatotropinoma cases and within heterogeneous FIPA families; isolated familial somatotropinoma cases represented 18% of FIPA cases and were younger at diagnosis than patients with sporadic somatotropinomas. Familial NS cases were younger at diagnosis (P = 0.03) and had more frequently invasive tumors (P = 0.024) than sporadic cases. CONCLUSIONS: Homogeneous and heterogeneous expression of prolactinomas, somatotropinomas, NS, and Cushing's disease can occur within families in the absence of MEN1/CNC. FIPA and sporadic cases have differing clinical characteristics. FIPA may represent a novel endocrine neoplasia classification that requires further genetic characterization. [less ▲]Detailed reference viewed: 69 (7 ULiège)
Diagnostic Characteristics and Therapeutic Responses in Acromegaly : The Liège Acromegaly Survey
; Petrossians, Patrick ; Daly, Adrian et al
in 50th Meeting of the German Endocrine Society and 23rd Meeting of Dutch Endocrine Society : Essen, Germany, 1-4 March 2006 (2006, March)Detailed reference viewed: 23 (1 ULiège)
Les patients acromégales sont-il mal pris en charge? De la mauvaise utilisation des bases de données
Petrossians, Patrick ; ; Daly, Adrian et al
in 23ème Congrès de la Société Française d'Endocrinologie - Abstract book (2006)Detailed reference viewed: 28 (1 ULiège)
Transsphenoidal surgery for Cushing's disease. Early and long-term results in 106 patients
Stevenaert, Achille ; Robe, Pierre ; Martin, Didier et al
Conference (2005, October 07)Detailed reference viewed: 11 (0 ULiège)
Connexin 30 expression in high grade gliomas : correlation with survival and resistance to ionizing radiation.
Robe, Pierre ; Nguyen Khac, Minh-Tuan ; Deprez, Manuel et al
Conference (2005, March)Detailed reference viewed: 38 (3 ULiège)
Symptomatic pituitary metastasis
; Dubuisson, Annie ; Robe, Pierre et al
Conference (2005, March)Detailed reference viewed: 13 (0 ULiège)
Gross total resection or debulking of pituitary adenomas improves hormonal control of acromegaly by somatostatin analogs
Petrossians, Patrick ; ; et al
in European Journal of Endocrinology (2005), 152(1), 61-66
Introduction: Invasive GH-secreting pituitary adenomas are rarely cured by surgery and although long-term therapy with somatostatin analogs (SSAs) may be employed, hormonal control is achieved in only 60 ... [more ▼]
Introduction: Invasive GH-secreting pituitary adenomas are rarely cured by surgery and although long-term therapy with somatostatin analogs (SSAs) may be employed, hormonal control is achieved in only 60% of cases. The impact of tumor debulking on subsequent control of acromegaly with SSAs has not been studied previously. Methods: We studied retrospectively the response to SSA therapy in acromegalic patients before and after incomplete surgical tumor excision. A case review identified 24 acromegalic patients who had received SSA therapy for 1 month before and after gross total resection or debulking of adenomas. No patient received radiotherapy or combination treatment with SSAs and dopamine agonists during the study. GH and IGF-I responses to SSAs were recorded pre- and postoperatively. Postoperative SSA therapy was begun after a washout period of 1–3 months to assess the hormonal effects of the surgery alone. Results: Before preoperative SSA treatment, 24/24 (100%) patients had elevated GH levels and IGF-I levels were elevated in 19/21 (90.5%) patients with recorded values. During preoperative SSA treatment, GH and IGF-I levels were normalized in 7/24 (29.2%) and 11/24 (45.8%) patients respectively. Following postoperative washout, GH was controlled in only 3/24 (12.5%) patients, while IGF-I was controlled in 8/19 (42.1%) patients with available data. During the second SSA treatment period, normal GH levels were seen in 13/24 (54.2%) patients, while IGF-I control was noted in 18/23 (78.3%). Conclusion: Gross total tumor resection or debulking increases the likelihood of achieving biochemical disease control with SSAs in acromegalic patients with adenomas that were not amenable to complete surgical resection and in whom primary SSA therapy was unable to achieve good biochemical control. [less ▲]Detailed reference viewed: 90 (7 ULiège)
Control of tumor size and hormonal hypersecretion in acromegaly : a large single-center experience
Daly, Adrian ; ; Petrossians, Patrick et al
in European Congress of Endocrinology - Abstract book (2005)Detailed reference viewed: 19 (1 ULiège)
Recurrent intracranial melanocytoma associated with a nevus of Ota.
; ; Kaschten, Bruno et al
in Acta Neurochirurgica (2005), 147(3), 313-5315Detailed reference viewed: 36 (1 ULiège)
Approaching the true prevalence of pituitary tumors
Beckers, Albert ; ; et al
in ENEA congress : Napoli, April 2004 (2004, April)Detailed reference viewed: 15 (0 ULiège)
Surgical debulking of GH secreting pituitary adenomas improves GH control of acromegaly by somatostatin analogs
Beckers, Albert ; Petrossians, Patrick ; et al
in ENEA congress : Napoli, April 2004 (2004, April)Detailed reference viewed: 21 (0 ULiège)
Primary central nervous system lymphoma - Report of 32 cases and review of the literature
Dubuisson, Annie ; Kaschten, Bruno ; Lenelle, Jacques et al
in Clinical Neurology and Neurosurgery (2004), 107(1), 55-63
We retrospectively analyzed 32 cases of primary central nervous system lymphoma (PCNSL). Five cases were diagnosed in the period 1987-1994, for 27 cases in the period 1995-2002. There were 17 men and 15 ... [more ▼]
We retrospectively analyzed 32 cases of primary central nervous system lymphoma (PCNSL). Five cases were diagnosed in the period 1987-1994, for 27 cases in the period 1995-2002. There were 17 men and 15 women whose median age was 69 years. Three patients were immunodeficient. The commonest symptoms were focal deficit (16 patients) and cognitive/behaviour disturbances (14 patients). Radiologically, a total of 47 contrast-enhancing lesions were observed in 32 patients; 18 patients had deep-seated lesions. All but two patients underwent histological diagnosis following craniotomy (11 patients) and/or stereotaxic biopsy (22 patients); diagnosis was obtained on CSF cytology in one patient with a third ventricle tumour. In the last patient, the diagnosis was based on the finding of marked tumour shrinkage under corticotherapy, despite two negative histological examinations. Treatment included surgical resection (10 patients), chemotherapy (25 patients) and/or radiotherapy (12 patients). According to the therapeutic recommendations of the GELA (Groupe d'Etude des Lymphomes de l'Adulte), 19 patients received at least two courses of high-dose methotrexate; intrathecal chemotherapy was used in 20 patients with methotrexate and/or cytosine arabinoside. Radiation therapy consisted of whole brain irradiation followed by a boost on tumour site. Nine patients received a combined treatment of chemotherapy and radiotherapy. Twelve patients showed rapid progression to death. At the time of last contact, 28/32 patients (88%) had died, all from PCNSL disease or from complications due to its treatment. The median Survival time was 13.9 months. We conclude that PCNSL is an increasingly frequent tumour. The diagnosis is obtained by stereotactic biopsy in the majority of cases. The prognosis appears dismal despite an intensive multidisciplinary therapeutic approach. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]Detailed reference viewed: 95 (16 ULiège)


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SOMERSWORTH — As shoppers were busy snagging deals on holiday gifts Friday morning, a small group of protestors gathered at Wal-Mart in Somersworth to voice their displeasure with the company's labor practices.
Wal-Mart workers and supporters marched in protest at a number of stores nationwide Thursday and Friday, including in New Hampshire, where groups demonstrated in Manchester, Derry and Salem.
The Wal-Mart store in Somersworth was also briefly the site of a protest movement on Friday morning, dubbed Black Friday because of its impact on the sales figures of the nation's retailers.
Around the country, demonstrators blasted the wages, benefits and treatment of employees of the world's largest retailer.
However, the efforts seemed to do little to keep shoppers away — Wal-Mart Stores Inc. said it was its best Black Friday ever.
A union-backed group called OUR Walmart has said that it held an estimated 1,000 protests in 46 states. The exact number is unclear. Walmart has refuted that estimate, saying the figure is grossly exaggerated and that the protests involved few of its own employees.
OUR Walmart, made up of current and former Wal-Mart employees, was formed in 2010 to press the company for better working conditions.
"These workers are dealing with incredibly low pay," said Jason Stephany, a regional spokesman for OUR Walmart. "They're dealing with unsafe working conditions, and when they speak out about those situations, they have repeatedly been met with retaliation from their employer, which is illegal under federal law."
Union officials say that the walkouts and demonstrations are to protest what it believes are Wal-Mart's retaliation tactics against workers who have been publicly speaking out about working conditions and wages. The tactics allegedly include scheduling changes and reduction in workers' hours.
Wal-Mart faced a worker walk-out in October ahead of its annual investor meeting that expanded to more than a dozen states and involved about 90 workers. Wal-Mart workers again walked off their jobs last week in Dallas, Oakland, Calif., and Seattle.
One of the largest demonstrations Friday took place in suburban Los Angeles. As many as 1,000 people took part at the height of the demonstration, including many who arrived in buses, sheriff's officials estimated.
Nine people were arrested for blocking a busy street in front of a Wal-Mart. Authorities said three of the nine people taken into custody were employees of the Paramount, Calif., Wal-Mart, which was doing a brisk business after the two-hour protest ended. Some shoppers continued to honk their car horns and wave in support of lingering protesters.
The world's largest retailer, based in Bentonville, Ark., last week filed an unfair labor practice charge with the National Labor Relations Board against the United Food and Commercial Workers International Union (UFCW).
It said the demonstrations organized by union-backed OUR Walmart threatened to disrupt its business and intimidate customers and other store workers.
Meanwhile, OUR Walmart filed its own charge on Tuesday against Walmart with the labor board. It cited attempts by Walmart to deter workers from participating in the walkouts, which the group believes to be legally protected.
Walmart's corporate communications office responded via email to requests for comment from Foster's regarding Friday's demonstrations.
David Tovar, vice president for corporate communications, said in a prepared statement that the number of protests being reported at Wal-Mart stores is "grossly exaggerated." Tovar said the company is aware of only "a few dozen" protests. Further, Tovar said at least 60 percent fewer Walmart associates missed their scheduled shifts this year compared with Black Friday last year.
"It was proven last night — and again today — that the OUR Walmart group doesn't speak for the 1.3 million Walmart associates," Tovar said in a statement provided shortly before 3 p.m. on Friday. "We had our best Black Friday ever and OUR Walmart was unable to recruit more than a small number of associates to participate in these made for TV events. Press reports are now exposing what we have said all along — the large majority of protesters aren't even Walmart workers."
Foster's staff writer Jim Haddadin and The Associated Press contributed to this report.
Demonstrators in Somersworth call for changes at Walmart
SOMERSWORTH — As shoppers were busy snagging deals on holiday gifts Friday morning, a small group of protestors gathered at Wal-Mart in Somersworth to voice their displeasure with the company's labor practices.


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By John Goralski
Sports Writer
Tony Membrino circled the track in a victory lap, drinking in the cheers from the grandstand at Stafford Motor Speedway. On Saturday, Sept. 28, a crowd spilled out of their seats to circle the black and purple car, and Membrino jumped onto the hood to get a better look through the mob.
He scanned the crowd and zeroed in on his target.
Membrino brushed past celebrating fans. He pushed through the other drivers and race officials to find his father, Tony Membrino, Sr. The two embraced in a wild hug to celebrate their SK Light division title. The cheering faded into white noise, and the father-son team drank in the moment.
"Without him, I wouldn't be here," Membrino said. "We don't have a lot of money or excessive sponsorship dollars behind us, so there's a lot of penny pinching involved. For everything we do, and everything we go up against, to come out on top again is a million dollar feeling."
Membrino has a racing pedigree that reaches back three generations. He has short track legends offering advice in the pit and a growing fan base at the Stafford track, but car racing is a big-budget commitment with high-priced equipment, tires, and quick turnarounds for major repairs. Still, the father-son duo have been holding their own on a shoe-string budget.
"He sacrifices so much just so we can go racing, and there aren't enough words to describe my gratitude for everything he does," Membrino said about his father's commitment as his crew chief. The two work side-by-side all week in a garage and tinker with the racecar long into the night. "We put ourselves through the ringer so we can succeed, and sometimes it seems we're in over our heads. I am beyond ecstatic that we can share this together."
Membrino's victory at the CarQuest Fall Final was his third one this season at the Stafford Motor Speedway. The points title championship is his third one in the past five years in two different divisions. The local driver has captured 17 top 10 finishes in 18 races this year. Twelve times, he's finished in the top five, but his third victory didn't come easily.
The car handled well in the practice rounds on Friday morning. With minor adjustments, Membrino climbed up to third place at the start of his heat race to earn a seventh place finish in the 20-lap feature. They fixed a stearing issue in the practice rounds, made a few slight adjustments in the heat race, but Membrino needed to finish at least three spots ahead of Chase Dowling to catch up in the standings on the final race. Membrino said that he felt good about his chances at the starting line of the feature race.
"Winning the race was my only objective," he said. "I knew that the points would take care of themselves. I had a ton of people there to support me. My grandfather made his first appearance at the track this year, along with a bunch of family members and a ton of my friends. There were probably around 20 people just at our pit before the race started, let alone all the other family and friends that were in the stands for the race."
From the drop of the green flag, Membrino had his hands full. Going into Turn 3, the car in front of him made a three-wide move and tangled up into a melee right in front of Membrino. Luckily, he saw it unfold. Membrino squared his front bumper with the tangle ahead, stood on the gas, and pushed through it to claim fourth place as the caution flag fell.
On the restart, it became a two-man race with Membrino and Tyler Hines as caution flags began to fall on the group behind them like a parade at the United Nations. Hines and Membrino survived the multiple restarts, including a 20-minute cleanup on lap 13 that cooled the tires before the final push to the finish. Suddenly, Membrino's steering issues returned.
"There was just something I wasn't liking with the right rear tire," he said. "The car wasn't sliding or pushing. It just felt like it wanted to take the wall down off the corners, but it was actually better with longer green flag laps than it was on restarts. So when it was time to go back to green with seven laps to go, with cooler tires and speedy dry all over the track, I didn't know what to expect."
He was able to hold onto the lead as Hines continued to challenge him from behind. With two laps remaining, the two were locked in a dogfight at the front of the pack. Membron protected the bottom of the track to try to force him to pass him on the top, and the gamble paid off. Hines tried to pass him on the right. The two raced side-by-side into the final two turns, but Membrino pulled away at the end to win by half a length.
"It was one heck of a race, and one heck of a win—not an easy one by any means," Membrino said. "Tyler kept me on my toes. He's a hockey player and those guys go all out, so I knew he wasn't going to make it easy on me."
It wasn't until Dowling pulled up alongside him and flashed the thumbs-up sign that Membrino realized that he'd regained the points title. Dowling finished fifth overall. Membrino captured the checkered flag. When the dust settled, Membrino scored the points victory by a slim, four point margin.
"It was just pandemonium from there. All those people that were at our pit earlier were all around me screaming, cheering, clapping, and throwing water all around," he said. "It was unreal…It just overwhelmed me. I thought to myself, 'All this for me?' It's a feeling I can't describe, but I wish everyone could experience just once."
Although the Stafford season is finished, Membrino still has one more race before he hangs up his gloves. He's currently ranked fifth in the NASCAR Whelen All-American Series Division III national standings, and he's ranked second in the NASCAR Whelen All-American Series state standings. Now, Membrino will try to improve his overall rankings with a final regional race.
"While we don't know what lies ahead of us for next year just yet, we have one more stop in our schedule this year," he said. "We're going to try and wrap the year up with another win at the World Series of Speedway Racing at Thompson International Speedway on October 19."
For now, Membrino will celebrate his victory with his local sponsors: Equipment Services, CWPM, Richards Corporation, TD Homers, Napa Valley Auto Supply, Jay Pahl Auto, Steve Greer, JMW Construction, Embroidery Works, and Membrino Electric.
To comment on this story or to contact sports writer John Goralski, email him at jgoralski@ southingtonobserver.com.
Capture the flag; Membrino wins his 3rd checkered flag to claim the SK Light title at Stafford
By John Goralski


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Roster Spots for Ivy League Heptagonal Championships Up for Grabs
NEW HAVEN, Conn.—Coming off a strong performance at the competitive Pre-Nationals Invitational in Terre Haute, Ind., last weekend, the Yale men's cross country team will not travel far this weekend when it makes the trip to New Britain, Conn., to compete at the CCSU Mini Meet on Friday. The meet, hosted by Central Connecticut State University, gets its name from the fact that competitors only run a 5K course—shorter than the 8K course run at most meets throughout the season.
Competing at the meet for the first time last season, the Elis dominated the field, finishing first overall with 26 points. The second-place team finished well behind the Bulldogs with 86 points, and all five of Yale's scorers finished in the top 10 overall. This season's race figures to be more of a challenge for the team, as only one member of last year's top seven (junior Alec Borsook, who finished 14th overall) will be returning to the meet this season. The Bulldogs are resting many of their athletes this weekend, both because seven of their top runners ran at Pre-Nationals last weekend and because the important Ivy League Heptagonal Championships are scheduled for the weekend following the Mini Meet. As a result, this Friday's race will provide some of the Elis' younger and less experienced athletes with a chance to shine. Of the seven runners slated to travel to New Britain, four are freshmen.
Head Men's Cross Country Coach Paul Harkins said he plans to use the results from Friday's race to help determine which runners receive the remaining spots to compete in the Heptagonal Championships.
"I like to see who is able to respond when there is a little bit of pressure involved,"
said Harkins.
The Bulldogs who compete at the Mini Meet should expect some familiar regional competition. This year's field will likely look similar to last year's, which featured the likes of Boston University, CCSU, Hartford, Providence and University of New Haven. At this point in the season, Providence, CCSU and Boston University are slotted fourth, eighth and 12th, respectively, in the USTFCCCA's Northeast Region rankings. Yale is currently ranked seventh in the region.
In addition to Borsook, the only other non-freshmen scheduled to compete in Friday's 5K are sophomore Will Botta and junior Tom Harrison. Harrison (25:18) and Borsook (26:01) both set 8K personal records when they last competed two weeks ago at the New England Championships, finishing second and fourth on the team, respectively. Harrison also finished in Yale's top seven at the Iona Meet of Champions earlier in the season. Botta, meanwhile, will be competing for just the second time this season.
The freshmen scheduled to run in New Britain are Ryan Douglas, Dan Grosvenor, David Hatch and Spike Sievert. Of the four, Douglas and Grosvenor have competed the most regularly this season. The pair ran at the Harvard-Yale meet, Iona Meet of Champions, New England Championships and Paul Short Invitational.
Even with the postseason on the horizon, Harkins is looking forward to the Mini Meet for its own sake.
"It will be exciting to see them get out hard and get after it on a much shorter course," he said.
Friday's race will begin at 3:30 p.m. Results will be available on www.yalebulldogs.com following the conclusion of the meet.
Report by Zach Schloss '15, Yale Sports Publicity


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Board of Directors
Takin' care of business!
Liv Bergþórsdóttir, Chairman of the Board
Liv has worked in telecommunications since 1998. Liv has participated in the foundation and development of the following companies and trademarks in Iceland: Tal, Vodafone, Sko and Nova. Liv has been the Managing Director at Nova since 2006, during which time the company has achieved very good results in the Icelandic mobile communications market. Liv was voted Marketer of the Year 2012.
Skúli Mogensen, Chief Executive Officer
Skúli has 20 years' experience in the high-tech, mobile communications and commercial sectors, as an entrepreneur, a CEO and an investor. He was among the founders of Íslandssími, Arctic Ventures and OZ Communications - where he was CEO, and later Chairman of the Board; until the company was sold to Nokia in 2008. Skúli is a progressive investor and sits on the boards of many tech companies, both in North America and Europe. He is a board member at, among others: Securitas, MP Bank, Datamarket and Redline Communication. Skúli was voted Iceland's Businessman of the Year in 2011.
Davíð Másson
Davíð worked both in the flight operations and sales & marketing departments at Air Atlanta Icelandic for 13 years and held management positions with the company in Iceland and abroad. In 2006 he became CEO of Avion Aircraft Trading and today he is a partner in Avion Capital Partners in Switzerland; a company specializing in consulting and the lease of aircraft to the aviation industry. Davíð is a graduate marketing coordinator from Florida Institute of Technology.
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Helga Hlín Hákonardóttir is a District Court Lawyer with over 19 years of experience working for Icelandic and international financial companies. She founded the law firm Lixia in 2011, servicing companies in the international finance and travel industry. Helga Hlín is part owner of Strategía, a consulting company that provides company and investor advisory services. She co-owns CrossFit Akureyri and is a corporate board member of companies and organizations such as Festi, Kaupás, Summa Management Company, and Greiðsluveitan. Helga Hlín graduated as a District Court Lawyer from The University of Iceland and has completed exams for the designation of Certified Securities Broker in Iceland.


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The Centre for the Study of Ministry was created in June 2009 by the TST Board of Trustee and is as an interdisciplinary, academic unit within the Toronto School of Theology (TST). Its two major purposes are:
- To oversee the Doctor of Ministry program.
- To support and promote interdisciplinary conversation, professional development, research, and publication in the study of ministry.
Through its supervision of students and academic administration, through collaborative policy-making, and through colloquia and other educational events, the Centre fosters interdisciplinary conversation among scholars in faith-based studies, humanities, health sciences and professional faculties. It develops the skills and understanding of religious scholars in methods of qualitative research. Through benefactions and grants, the Center will support individual and team research.
At present, the regular faculty members of the Centre are professors with graduate degree status, both full and associate, at TST's member or affiliate colleges. In addition, several faculty members from other divisions of the University of Toronto serve as partners in conversation.
Ministry is a complex socio-religious reality that involves the resources and research methods of many disciplines. It includes congregational leadership and pastoral care, religious education, sacred music, social advocacy, prison and health chaplaincies, evangelism and international development. Accordingly, students and researchers benefit from the guidance of a wide variety of specialists in such areas as health research, social work, education, management, psychology, sociology, family studies, cultural studies, history, information science, law and music, as well as theology and pastoral studies. Although the Doctor of Ministry program has always had an interdisciplinary dimension, the creation of the Centre for the Study of Ministry reflects a fresh commitment to promoting conversation about religious ministry among faculty members and students across the University of Toronto.
Administrative Structure of the Centre
The Interim Director of the Centre (Dr. Sarah Travis) is supported by an Academic Committee of five faculty members, and by a part-time Program Administrator. The constitution of the Centre for the Study of Ministry, as found in the proposal approved by the TST Board of Trustees, can be viewed here.
Graduates of the Centre
Over 150 people have graduated from the Doctor of Ministry program since 1977. Most serve in congregational ministry, other areas of church leadership; many are theological educators. A fairly representative sample can be found here.
Faculty Members of the Centre
- John Bowen, MA, CertEd (Oxford), DipTh (London), DMin (McMaster), Director of the Institute of Evangelism, Wycliffe College: evangelism, culture, preaching, church planting, C.S. Lewis
- Pamela Couture, BA (Ashland), MDiv (Garrett-Evangelical), PhD (Chicago), Jane and Geoffrey Martin Chair in Church and Community, Emmanuel College: practical theology
- Charles J. Fensham, BTh, BTh Honours, MTh, DTh (South Africa), MTh Pastoral Counselling (Waterloo Lutheran), Associate Professor of Systematic Theology, Knox College: theology of mission, ecclesiology, faith and contemporary culture, intercultural theology, Reformed theology, Reformed spirituality.
- J. Dorcas Gordon, BA (Toronto), MDiv (Knox), ThM (Newman), ThD (Knox), Associate Professor of Biblical Interpretation and Preaching, Knox College: preaching, social science method, feminist method; formerly director of the TST Doctor of Ministry program
- Alan L. Hayes, BA (Pomona), BD, PhD (McGill), Bishops Frederick and Heber Wilkinson Professor of the History of Christianity, Wycliffe College: Canadian Christianity, theological education, faith and culture
- Andrew Irvine, BA (Dalhousie), MDiv (Acadia), PhD (St. Andrew's), Lecturer in Pastoral Theology, Knox College, and Director of the Doctor of Ministry Program, Toronto School of Theology: practice of ministry, congregational studies, clergy care
- Allen G. Jorgenson, BSc (Alberta), MDiv, STM (Lutheran, Saskatoon), PhD (St. Michael's), Associate Professor of Systematic Theology, Waterloo Lutheran Seminary, Wilfrid Laurier University: word and sacrament; contemporary theology
- Abrahim H. Khan, BS (Howard), BD (Yale), MA, PhD (McGill), Professor of Divinity, University of Trinity College: ethics, cross-cultural studies in religion, religious pluralism, religion and mental health, church in the public sphere
- Kristine Lund, BSc (Calgary), MDiv (Lutheran Theological Seminary, Saskatoon), PhD (Alberta). Assistant Principal and Director Of Contextual Ministry and Spiritual Care and Counselling, Waterloo Lutheran Seminary, Wilfred Laurier University: pastoral counselling, professional ethics, leadership in ministry
- Stuart Macdonald, BA, MA (Guelph), MDiv (Knox), PhD (Guelph), Professor of Church and Society: ministry, quantitative analysis, congregational development
- David Pfrimmer, BA (Waterloo Lutheran University), MDiv (Waterloo Lutheran Seminary), MA (Wilfrid Laurier), DMin (Princeton), Principal Dean, Waterloo Lutheran Seminary, Wilfrid Laurier University: applied Christian ethics, public theology, social justice
- Thomas Power, BA (Dublin), MLS (Toronto), PhD (Dublin), Adjunct Professor of Church History, Wycliffe College, and Theological Library, The John W. Graham Library of Trinity and Wycliffe Colleges: History of theological education, research methods, theological bibliography
- Ephraim Radner, AB (Dartmouth), PhD (Yale), Professor of Historical Theology, Wycliffe College: theology of church, ministry, and sacraments
- Joseph Schner SJ, AB (Fordham), MA (Windsor), MDiv (Regis - St. Mary's, Halifax), STL (Regis), PhD (Toronto), Professor of Psychology and Psychology of Religion, Regis College: developmental and child clinical psychology, psychology of religion
- Nam Soon Song, BA (Presbyterian College of Korea), MA, EdD (Presbyterian School of Christian Education, Richmond, Virginia), Ewart Professor of Christian Education and Youth Ministry, Knox College, and Director of the Canadian Asian Centre for Theology and Ministry: religious education, youth and children's ministry, curriculum
- Michael Stoeber, BA, MA (Calgary), PhD (Toronto), STL (Regis), Professor of Spirituality, Regis College: philosophy of comparative spirituality (especially Christian and Hindu), religious experience, evil, suffering, eschatology, theological anthropology, ethics and spirituality.
- J. Glen Taylor, BA (Calgary), ThM (Dallas), MPhil, PhD (Yale), Associate Professor of Old Testament Interpretation and Proclamation, Wycliffe College: preaching and proclamation
- David Reed, BA (Barrington), MA (Andover Newton), PhD (Boston), Professor Emeritus of Pastoral Theology, Wycliffe College: congregational life, family and sexuality, spiritual trends
Partners in Conversation
From the Faculty of Music, University of Toronto
- Lori-Anne Dolloff, MusBac, MusM, BEd (Toronto), LTCL (Trinity, London), PhD (OISE/Toronto), Associate Professor of Music Education: choral music; artistic development of children; narrative research methodology; reflective practice; world musics, intercultural education
From the Faculty of Law, University of Toronto
- Jennifer A. Nedelsky, BA (Rochester), MA, PhD (Chicago), Professor of Law and Political Science: feminist theory; human rights; faith and public policy; theories of judgment; history of law
From the Factor-Inwentash Faculty of Social Work, University of Toronto
- Ramona Alaggia, BA, BSW (McMaster), MSW, PhD (Toronto), Associate Professor in the Factor-Inwentash Chair in Children's Mental Health: child and adolescent mental health issues, family violence, sexual abuse, theory and values in social work, qualitative research
From the Dalla Lana School of Public Health, University of Toronto
- Joan M. Eakin, PhD (McGill), Professor, Social and Behavioural Sciences Division; Director of the Centre for Critical Qualitative Health Research; Adjunct Senior Scientist, Institute for Work & Health: qualitative research methodology; social theory; health and the social relations of work.
From the Faculty of Applied Science and Engineering, University of Toronto
- Bill Vanderburg, BASc, MASc, PhD (Waterloo), PEng, FCAE, Associate Professor of Civil Engineering; cross-appointed professor, Department of Sociology; Full Member, Centre for Environment; Director, Centre for Science, Technology, and Society: science, technology, and culture; environmental issues; religion and technology in the thought of Jacques Ellul
From the Ontario Institute for Studies in Education, University of Toronto
- Elizabeth Smyth, BA (McMaster), BEd (Toronto), MA (McMaster), EdD (Toronto), Professor, Department of Curriculum, Teaching, and Learning, OISE; Vice-Dean, School of Graduate Studies, University of Toronto: religion and Canadian history, the rise of the professions, women religious and Canadian history, technology and learning
From the Faculty of Medicine, University of Toronto
- Giles Scofield, AB (Princeton), JD (New York University School of Law), MA (Yale Divinity School), Associate Professor, Faculty of Medicine; Clinical ethicist, Centre for Clinical Ethics: bioethical reasoning, theology of Paul Tillich, informed consent, organizational ethics, postmodern ethics
From the Department of East Asian Studies, University of Toronto
- Vincent Shen, BA, MA (Fu-Jen), MA, MA (Soc. Sci. Louvain), PhD (Louvain), Richard Charles and Esther Yewpick Lee Chair in Chinese Thought and Culture: Chinese philosophy and religion, phenomenology, comparative philosophy and religion, Christian thoughts and Chinese culture
From the School of the Environment
- Stephen Scharper, BA Honours (Toronto); MA (Toronto), PhD (McGill), Associate Professor, Department of Anthropology, U of T Mississauga and School of the Environment:environmental ethics, environmental worldviews, liberation theology and ecology, religions and environmentalism
From Ryerson University
- Klaas Kraay, BA, PhD (Toronto), Associate Professor of Philosophy: philosophy of religion (contemporary analyses of models of God, arguments for and against theism, conceptual issues of religious diversity), metaphysics, epistemology
Governance of the Centre
Joseph Schner SJ, Director
Members of the Academic Committee
- Sarah Travis, Interim Director, DMin Program
- Alan L. Hayes, Director, Toronto School of Theology
- Jaroslav Skira, Director, Graduate Centre for Theological Studies
- Bradley McLean, Coordinator, Graduate Centre for Theological Studies
- Abrahim Khan, Trinity College


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Meet up with other Chicago area singles for a night of speed dating. Dates will last 5-min as the men rotate from table to table. Dress is business casual. Matches will be notified the following day.


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