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The protein encoded by ABCC6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCC6 Proteins (15) and ABCC6 Kits (14) and many more products for this protein.
Showing 10 out of 41 products:
Human Monoclonal ABCC6 Primary Antibody for FACS, IHC (fro) - ABIN535128
Bergen, Plomp, Schuurman, Terry, Breuning, Dauwerse, Swart, Kool, van Soest, Baas, ten Brink, de Jong: Mutations in ABCC6 cause pseudoxanthoma elasticum. in Nature genetics 2000
Show all 2 Pubmed References
Human Monoclonal ABCC6 Primary Antibody for ELISA, WB - ABIN559916
Pinckard, Sheehan, Arthur, Schreiber: Constitutive shedding of both p55 and p75 murine TNF receptors in vivo. in Journal of immunology (Baltimore, Md. : 1950) 1997
Show all 2 Pubmed References
Six disease causing amino acid mutations in human MRP6 are a normal feature of abcc6 in fish, suggesting they do not have a deleterious effect on the protein.
the L0 cytoplasmic loop of human multidrug resistance protein 6 was characterized.
A novel homozygous frameshift variant in ABCC6(c.1799_1805dupGTCTGGT) was identified in one family and two previously reported missense variants (c.2294G > A and c.2974G > A) in compound heterozygous form in the other family.
Study shows that ABCC6 loss of function in pseudoxanthoma elasticum PXE has a profound impact on vascular purine metabolism through modified arterial gene expression, soluble nucleotidase activities, and, finally, circulating nucleotide levels.
This study identified heterozygous ABCC6 variants as a risk factor for ischemic stroke.
Pilot study examined 3 candidate genes, ectonucleotide pyrophosphatase/phosphodiesterase (ENPP1), ATP Binding Cassette Subfamily C Member 6 (ABCC6), and 5'-Nucleotidase Ecto (NT5E) involved in pyrophosphate (PPi) and inorganic phosphate (Pi) metabolism, which may predispose to coronary arterial or valvular calcification; report 4 new genetic variants potentially related to coronary calcification.
The novel ABCC6 splicing mutation c.1177-2A>G results in multiple splicing patterns. Endogenous U2 to U12 conversion may occur in humans in a disease state. Peripheral blood mononuclear cells can be reliably used to study ABCC6 RNA.
Serum levels of MRP8/MRP14 and MRP6 were up-regulated in patients with Graves' disease (GD) and Hashimoto's thyroiditis (HT). In addition, mRNA expression of MRP proteins in PBMCs and the thyroid gland was markedly elevated in these patients.
High URG7 reduces the ER stress by decreasing the amount of unfolded proteins, by increasing both the total protein ubiquitination and the AKT activation and reducing Caspase 3 activation.
Two compound heterozygous ABCC6 loss-of-function mutations, c.4182_4182delG (p.Lys1394Asnfs*9) and c.2900G > A (p.Trp967*), were found
Genetic analysis revealed three nonsense, four frame-shift, one exon deletion and 13 missense mutations in 73 Japanese pseudoxanthoma elasticum patients.
in a French cohort with pseudoxanthoma elasticum, study identified 538 mutational events with 142 distinct variants, of which 66 were novel
ABCC6 overexpression may also contribute to nilotinib and dasatinib resistance in vitro. With nilotinib and dasatinib now front line therapy options in the treatment of CML, concomitant administration of ABCC6 inhibitors may present an attractive option to enhance TKI efficacy
Using an integrated pathway-based approach, we identified polymorphisms in ABCC6, ABCB1 and CYP2C8 associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma
ABCC6 knockdown HepG2 cells show: 1) intracellular reductive stress; 2) cell cycle arrest in G1 phase; 3) upregulation of p21Cip p53 independent; and 4) downregulation of lamin A/C. the absence of ABCC6 profoundly changes the HepG2 phenotype, suggesting that Pseudoxanthoma elasticum syndrome is a complex metabolic disease that is not exclusively related to the absence of pyrophosphate in the bloodstream.
ABCC6 deficiency can be rescued by 4-phenylbutyrate therapy in a mouse model expressing human variants
Biochemical and cell biological analyses demonstrate these mutations influence multiple steps in the biosynthetic pathway, minimally altering local domain structure but adversely impacting ABCC6 assembly and trafficking. The differential impacts on local and global protein structure are consistent with hierarchical folding and assembly of ABCC6.
The results suggest that a transmembrane domain is not required for transport function and that a cytosolic loop maintains ABCC6 in a targeting-competent state for the basolateral membrane and might be involved in regulating the nucleotide binding domains.
The results of this study showed that mtDNA(atp6) variants were actively involved in schizophrenia in some families with maternal inheritance of this
Pseudoxanthoma elasticum is due to mutation of the ABCC6 gene on chromosome 16.
Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolically active tissues.
abrogated ABCC6 function does cause alterations in the metabolic profile of the liver in accordance with PXE being a metabolic disease originating from liver disturbance
bisphosphonates may be helpful for prevention of mineral deposits in Pseudoxanthoma elasticum and generalized arterial calcification of infancy caused by mutations in the ABCC6 gene.
In a mouse model of CKD, ABCC6 protein expression was decreased in liver and kidney, however mRNA levels were unchanged.
In the Abcc6(-/-) genotype, dermal fibroblasts actively contribute to changes that promote matrix calcification; these cells can be further modulated with time by the calcified environment, contributing to the age-dependent progression.
This study showed that the expression of ABCC6 in liver is an important determinant of calcification in cardiac tissues in response to injuries
Magnesium oxide reduces carotid intima media thickness in Abcc6-/- mouse model for pseudoxanthoma elasticum.
Studied the role of genetic modulation and the role of diet in nephrocalcinosis using two established mouse models of ectopic mineralization, Abcc6(tm1Jfk) and Enpp1(asj) mice.
Report lower elasticity and increased myogenic tone without major changes in agonist-dependent contraction in aged Abcc6(-/-) mouse model of pseudoxanthoma elasticum.
the development of cardiac hypertrophy in the 24-month-old Abcc6(-/-) mice suggests that old pseudoxanthoma elasticum patients might be prone to developing late cardiopathy.
ABCC6 is in the basolateral membrane, mediating the sinusoidal efflux of a metabolite from the hepatocytes to systemic circulation.
A single-nucleotide polymorphism in the Abcc6 gene associates with connective tissue mineralization in mice similar to targeted models for pseudoxanthoma elasticum.
Our finding that ABCC6 localizes to the mitochondria-associated membrane has implications for its mechanism of action in normal and diseased states.
Abcc6 as a novel modulator of cardiac myocyte survival after cardiac ischemia-reperfusion (I/R) injury.
These results show that VK3GS is not the essential metabolite transported by ABCC6 from the liver and preventing the symptoms of pseudoxanthoma elasticum.
genetic and biochemical characterization; contribution to aortic calcification
Upregulation of Abca4 in the liver is a tissue-specific compensatory consequence of the 'knock-out' of Abcc6 in mice.
The level of Abcc6 synthesis was investigated in the liver and kidneys and the phenotype of a beta-thalassemia mouse model (Hbbth3/+) for a period of 14 months.
Abcc6 and Rag1 have roles in ectopic mineralization in a murine model of pseudoxanthoma elasticum
the presence of Abcc6 in elastic tissues is not required for elastic fiber assembly
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
ATP-binding cassette sub-family C member 6
, anthracycline resistance-associated protein
, multi-specific organic anion transporter E
, multidrug resistance-associated protein 6
, ATP-binding cassette, sub-family C, member 6
, multidrug resistance-associated protein-6
, ATP-binding cassette, sub-family C (CFTR/MRP), member 6
, MRP-like protein 1
, liver multidrug resistance-associated protein 6


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Ben Nevis avalanche victims revealed as French and Swiss climbers
Three climbers who died after an avalanche on the UK's highest mountain were French and Swiss, Police Scotland have said.
Two of the men caught on Ben Nevis were French, aged 41 and 32, and the third was a Swiss 43-year-old.
A fourth man, 30-year-old Swiss national Mathieu Biselx, remains in a stable condition at the Queen Elizabeth University Hospital in Glasgow after Tuesday's avalanche.
Swiss media reported the group were members of the Club Alpin Suisse de Sion (Swiss Alpine Club, Sion).
They were caught by the river of snow and ice in Number 5 gully as Storm Gareth blew in with strong winds, triggering a huge search and recovery operation in "brutal conditions", a rescuer said.
One of the climbers died "pretty instantaneously", according to Donald Paterson, deputy team leader of Lochaber Mountain Rescue Team (MRT).
Another could not be saved despite receiving CPR for half an hour.
Speaking from hospital where he is being treated for serious injuries to both legs, Mr Biselx said his companions were experienced climbers who took advice from local guides and were staying with one.
He said they had been given two routes to take on the mountain and went on one in the morning with no problems.
As they still had time, they suggested doing the second one in the afternoon – assuming they had taken the necessary precautions.
Upon reaching the second route they saw there had already been an avalanche there but had barely reached the area when they were swept away.
Mr Biselx, president of the alpine club and father of a little girl, said he was "amazingly lucky".
He told Le Nouvelliste: "We weren't very high up and suddenly we heard a noise. We looked round and two seconds later we were carried away by heavy, compact snow.
"When I regained consciousness only my head and an arm were sticking out of the snow."
He described his companions as "wonderful" people who were also fathers, adding: "It's terrible they're not here anymore. They won't see their families again."
First Minister Nicola Sturgeon said the fatalities were "absolutely tragic", while Skye, Lochaber and Badenoch MSP Kate Forbes said it was "heartbreaking".
Brian Tregaskis, Lochaber MRT secretary, also paid tribute to the climbers and his team.
They were joined by Glencoe MRT and around 30 volunteer mountain rescuers who happened to be training in the area.
He said: "The members of the Lochaber and Glencoe Mountain Rescue teams did an incredible job in very difficult conditions.
"We'd like to extend our deepest sympathies to the loved ones of those who lost their lives and we hope the surviving casualty makes a full and speedy recovery."
Tuesday's incident follows two recent fatal accidents on the mountain, which at 1,345m is the UK's highest.
On New Year's Day, a 21-year-old German woman, who was a student at Bristol University, died after she fell from a ridge she had been climbing with three other people.
She had been hiking on what is known as the "ledge route" when she fell around 500ft.
In December, Patrick Boothroyd, 21, from West Yorkshire, died after falling in the Tower Gully area.

subset: commoncrawl


text: Winner High Waisted seamless leggings - Navy / Red £55.00 Size Small (UK 6-10) - £55.00 Medium (UK 12-14) - £55.00 NEW IN! All hail the WINNERS! The latest member of our seamless family. These tights are our most flattering so far with an extra high/wide compression waistband that makes your waist look... SHARE: View Full Details


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I've been using ordinary blue painters' tape for blocking my geometric paintings, and while it's pretty good, there is inevitably some seepage of paint that I then have to touch up. It's annoying.
Today I went to the hardware store to get some new tape because I'm running out. I explained my dilemma to the assistant and asked what tape to use. He says FrogTape. It claims to have complete colour block Has anyone here used it and if so, how effective was it in preventing seepage? It's more expensive than the blue tape, so it had better work!
Views: 203
I just recently bought some of this tape too Ev and yes it does help.
On internet site I looked on said to tape with blue painters' tape, paint the edge between the tape/canvas with a thin line of acrylic gloss, let it dry, then paint what you want. That sounds like it wouldn't work. Who knows?
That's pretty good delineation, Ruth. No, leakage.
Exactly what I wondered, Ruth. Too, wouldn't matte medium be better than gloss if you have to paint over?
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Gumbo Groove's music is an adventure in genre bending. They call it Folk-Fueled Fungrass. Snatches of David Grisman-like riffs give way to New Orleans second line simmers, while shades of the Grateful Dead can be heard wending amongst the chordal carousings. Always friendly, always fun, Gumbo Groove is a musical incident looking for a place to happen.
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Earlier Event: August 22Dear Mr. Henshaw... live at the Arbor Bar!
Later Event: August 26baqqalaõ... live at the Arbor Bar!


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Born to an artistic mother and civil engineer father, Alisha Olson inherited a love of both art and mathematics. As a high school sophomore, she realized architecture could be the perfect way to combine her interests, and she's been on that path ever since.
Now a Project Architect, Alisha has vast experience managing commercial construction projects from beginning to end. She's adept at communicating with clients, problem solving, and keeping the bottom line in mind. Alisha has worked on projects ranging from a 1-million-sq.ft. industrial park to car dealership renovations, and each project gives her a chance to learn: "That's what gets me up in the morning, a thirst for knowledge and moving forward."
Alisha is a fan of her son's Little League team and an avid gardener, canning the fruits of her labor with her husband each year and perfecting the art of making pomegranate jelly.
Licenses and Certifications
Licensed Architect: AZ, CA
LEED Accredited Professional (LEED AP)
U.S. Green Building Council (USGBC)
The National Association of Women in Construction (NAWIC)
International Council of Shopping Centers (ICSC)
Commercial Real Estate Women Network (CREW)
Board of Directors – Habitat for Humanity of Greater Sacramento
Alternate Member – Arts, Culture and Historic Preservation Commission for the City of West Sacramento
Alisha Olson, RA, LEED AP
Project Architect / Associate
BA, Architecture, University of Arizona, 2005


text: Landscape is a product of economic activities and an asset associated with a society's productivity levels and the relations of production. Despite the range of projects —self-owned, for-sale,or public infrastructure — that designers undertake, life-cycle benefits such as rental returns and public satisfaction should always be considered. By interpreting landscape design as an asset management, this article highlights the third-party role of asset managers who coordinate the benefits of all stakeholders at different stages through negotiation of design options. Designers are also expected to have a product and user thinking, acquire general and interdisciplinary knowledge of certain businesses through role rotations, cross-department meetings, and diverse project teams to improve design proposals, and strengthen mechanisms of pre-occupancy engagement and post-occupancy evaluation.


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As the countdown to Lana Del Rey's Honeymoon continues, she's shared another taste of what's to come on her next studio album. On Wednesday, the singer dropped by Zane Lowe's Beats 1 radio show to debut the album's latest single, the hazy and hypnotic, "Music to Watch Boys To."
The track follows the release of lead single "Honeymoon" and its follow-up, "High By the Sea." After premiering the track, Del Rey talked to Lowe about staying true to herself after putting out three studio albums. Check out the whole interview here.
Honeymoon is due out Sept. 18.
Related Stories
•Lana Del Rey releases eerie new track, 'Honeymoon'
•Lana Del Rey's 'High By The Beach' is her catchiest song yet
WANT MORE EW? Subscribe now to keep up with the latest in movies, television and music.


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The Caribbean Development Bank (CDB) has approved a US$357,200 loan to the Barbados Government for improvement to the cargo facilities at the Grantley Adams International Airport (GAIA).
The GAIA Inc. is expected to conduct an extensive analysis to assess the current and future needs, as well as the type of infrastructure that will best create a world-class facility resulting in an upgrade of the airport.
Following a meeting today, the CDB issued a release saying the upgrade should result in improved international competitiveness and multiple benefit to SMEs in particular.
Among the outcomes of the study will be a gap analysis of the existing operations, physical infrastructure and proposed operations, infrastructure required to accommodate forecasted cargo opportunities and facility demand.
The study is also expected to produce security considerations applicable international standards, for both operations and physical infrastructure.
The statement said: "Developing and presenting physical development options, including but not limited to recommendations as to the type of operations (optimal mix and layout of floor space) that should be provided for each of the proposed options", was also to be a feature of the study."
CDB Vice President of Operations Dr Carla Barnett said: "Investments in improved logistics and supply chain management can help maximize opportunities that exist for improvement in the productivity of the transportation system. Trade logistics in Barbados require institutional reform and investment in infrastructure in order to improve efficiency in the processing goods and services in trade.
The development of modern air cargo facilitation will be critical in achieving this goal." According to data published by GAIA Inc, in 2013 it loaded 8.2 million tonnes of cargo and unloaded 12.1 million tonnes.
In the CDB's Country Strategy Paper 2010-2013, Barbados identified the high cost of doing business as a major issue affecting the international competitiveness of local businesses.
The release stated that "Small businesses are especially vulnerable to high cost structures and the services industry is dominated by time-defined international transactions.
Improved air cargo operations enhance the opportunity to leverage logistics and supply change management to enhance trade facilitation".
It says the bank focuses on helping to build a more resilient, sustainable and secure Caribbean through funding and technical support.
In 2013, CDB approved $139 million in loans and $28.4 million in grants from the Basic Needs Trust Fund. (PR/MM)


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The Wall Street Journal continues to deliver the news in forms cooler than that dead-end paper product. Check out their phone-only app release below. Just when you think the only giant powerful corporations control the mobile industry, a streaming music "little guy" arrives with a cool update. And just for fun, help a busy bee on his appointed rounds.
You'd think every bee would be great at flying. Not this one.
This bulbous bee can barely get off the ground and it needs your help to get it daily work of collecting pollen, honey, and other sweets. Use your finger to guide the bee over a series of rolling hills until it can use the momentum to catch some air and remain sky bound for a few seconds. At the end of a run you'll see a tally of your collection work and the status of whether or not you've met your quota.
The best part of the game is the circus-like soundtrack and the bright, inflated graphics. A good choice for kids.


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Nash Football, the Russian football network. Working in a foreign language, I developed and designed the logo for this Russian network. The design takes it cues from the Russian Football Premier League trophy, and celebrates the diversity of teams in the league.
Client: Nash football
Creative Director: Jocelyne Meinert, Shannon Wong, Jordan Greenstein, Santosh Isaac
Producer: Mike Moore
Produced for: bigstudios
Role: Concept, Design, 2D & 3D Animation, Compositing, Rendering, Logo Design, Creative Direction


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Jump Rings for Chain-Making
I found a nice source for jump rings: Spiderchain Jewelry. Some very helpful pages are the Favorite Weaves and Sample Pictures. The "shopping cart" is really a calculator that sends an email with an order number to you and to Spider. You then follow up separately with payment (PayPal accepted). You can include some comments about what you're trying to build (which I did) and Spider will sanity check your order (which he did) which is a nice touch.
My magpie eye got stuck on the niobium rings, which are especially pretty in mixed colors. I got these: air mix. Now I just hope they get here in time for the Bead Party this Saturday :-)


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Stadia Catering
We're leading a revolution in food at stadia across the UK, offering greater choice, quality and value within our stadium catering service, and introducing innovations in technology that make service faster and more enjoyable for fans.
We help our clients to reinvent their sports stadia, to tap into a new readiness among sports fans to spend more time and money enjoying themselves at stadia, often with their families. We bring an inspired new approach to food services at sports venues which increases customer satisfaction among the fan base and greater spend. It also opens up the opportunity for far more all-year-round income from conference and banqueting facilities on non-match days.
We have a dedicated team specialising in services at sports venues, operating right at the leading edge of exciting new food offers to transform the customer experience. This team is proven both at world famous stadia and with clubs at an earlier stage in expanding their franchise.
We provide every type of stadia catering and food service at major events, from fine dining to cafeteria and fast refreshments and snacks for large numbers of customers. We use the best ingredients to create exciting offers at great value. And we ensure our service delivers the best customer experience.
We also offer a specialist marketing team to help clients maximise the value of their stadia by developing revenues from corporate and private bookings for conferences, meetings and celebrations.


text: Blog What You Need to Know When Replacing a Window in an Existing Wall September 11, 2018 When it comes to home repair projects, few choices can make a more dramatic change than replacing your home windows. But while many other projects can be taken care of with a little bit of elbow grease and a good strategy, replacing a home window requires significant work and a bit of technical smarts. Because of that, replacing your windows is no easy job. You'll want to identify what type of window is necessary, the specific plans required for replacing the window based on the size of the opening, and what materials it will take to create the correct fit for your new window. Here are a few thoughts you may wish to think about: What is Your Frame's Condition? The condition, or even presence, of the window frame is the first significant factor in matching the proper type of window to your replacement job. If you are creating a new window frame, removing a damaged frame, or otherwise tearing the wall down to the studs, consider new construction windows, also called full frame replacement windows. Pocket replacement windows can be placed in projects where the window frame is not being taken out, is in good condition and properly leveled. The size of your window will also play a role in which kind of window you should use. Replacing a window with one that is the same size will make a pocket replacement window more likely. But, upgrading your window to a larger size will necessitate uninstalling the previous frame and creating a new frame to fit your larger window as part of a full frame installation. That means a full frame replacement window will be demanded for the job. Removing the Old Frame Selecting a full frame replacement window, as the name infers, typically means replacing the existing window frame, sashes and screen. This can typically be done with a utility knife, screwdrivers, pry bar, hammer, putty knife and circular saw, depending on your existing window. To safeguard your home exterior trim when uninstalling the frame, set a block of wood between the wall material and window, and then use a pry bar to take out the old window trim. Full Frame Window Options Two window styles can meet your needs when working on a full frame window installation: Nail fin windows and block frame windows. Nail fin windows are frequently seen in new construction projects, or any project where the walls will be exposed to the frame (studs). These windows include a thin piece of metal connected to the window itself that runs around the outer edges of the window frame. When installing the window to a new frame, this nail fin joins the window directly to the house's studs and is hidden between the interior and exterior of your home. Adding a nail fin window can be both hard work and may require the building of a new window frame or removal of siding so the builder can add the nail fin to the studs. Nail fin windows are easier to install in new construction (for example, when adding a room to your house), as the window is installed before the rest of the wall is completed around it. Further, if you are wishing to install a nail fin window to a current wall in a section of the house where a stone or brick exterior would also have to be removed, the process might not be worth the effort needed. Block frame windows offer a choice for jobs where nail fin windows would be more difficult to place. These windows come without a nail fin and are designed to sit inside existing window flashing (the area of the window that holds material to prevent water from entering into the walls) with little new construction work. This makes block frame windows a standard replacement for many older homes that presently have a window structure in place or houses with siding or brick exteriors that would otherwise have to be impacted or removed to install a nail fin window. Using Your Existing Frame Replacement pocket windows are slightly different than full frame replacement windows and are built to fit inside an existing window frame. While the existing window sashes and exterior stops of the window should be taken out for the new window to be installed, pocket replacements allow homeowners to keep the original frame, trim, siding and casing. Just as with full frame window replacement, the home exterior around the window opening will impact how the pocket replacement process works, this time with less steps. Unlike full frame replacement window removal, most of the existing sash, hinges and operating hardware will be attached with screws that must be uninstalled before clearing away the head, jamb and sill stops with a pry-bar. Similar to the full frame replacement window, placing a piece of wood to safeguard your wall exterior when removing the old window is a smart way to help prevent any accidental damage. After pulling out the existing sashes and inspecting and readying the opening, the replacement window can be placed into the opening and existing frame. Make sure to plumb, level and square the window at each step of the installation to have the best chance for a proper, balanced fit. Consult with a Professional Installer The steps required to replace a window in an existing wall require a clear knowledge of your design ideas and a specific installation of your window. You can review detailed step-by-step installation instructions based on both the style of window, as well as the type of window opening, at install.pella.com. Even with these detailed instructions, a number of homeowners discover that the chance of accidental damage to their home (as well as the time, price and labor demanded) make window installation a project they'd rather not take on. Planning with a professional home window installation expert, like the staff at Pella of Petoskey, provides the technical knowledge and know-how to do the job correctly. No matter where you are in your home window replacement plans, get in touch with a Pella professional today. Even if you are thinking about replacing a home window on your own, a technician can help determine what installation method is correct for your home and discuss installation plans. Back to Blog


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The Old and New Testaments of the Bible can sometimes seem like contradictions of one another. In the Old testament, God speaks emphatically about obedience and the dire consequences that come as a result of disobedience. Yet the New Testament is a reflection of God's grace and mercy shown to us.
With two seemingly different ideas it can be difficult to know what God expects of us. Is all hope lost if we sin? Or does God show mercy to us and judge us based on our intent?
Recently, while visiting my sister's church in Gulfport, Mississippi, I heard a sermon that was particularly convicting. The pastor referenced Malachi 1 and how ancient Israel was offering up blind, blemished, and broken animals as sacrifices to God, when He required the best to be offered to Him.
The children of Israel were blatantly disregarding God's commands.
It reminded me of how we can treat God in a cavalier way and expect Him to bless us. Throughout the Bible in both the Old and New Testaments, God makes it expressly clear that He does have a standard that He expects us to uphold. And when we enter God's house of worship, we should always offer him our best.
How do we offer God our best though? And what does "our best" look like?
Leave your thoughts and comments below.


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Does your business need Cyber & Data Liability Insurance?. . .
Do you know the cyber risks to your business?
How secure is your data?
Is your data protected if a laptop is stolen?
Cyber crime is growing at an alarming rate.
Your reputation is important to your business.
Do you take credit card payments or store credit card information for recurring payments?
Do you store personal information about your customers?
Do you have a data breach disaster plan in place?
Want to learn more about Cyber & Data Liability Insurance?
Fill out the form below & download our FREE e-book.


text: For 21 years, Katherine Ann Finley had been working her way up through the ranks at the Federal Employees Credit Union. Finley, 44, began working there as a teller and had served as the credit union's vice president for the past 10 years. She was born and raised in Oklahoma City.


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One Year Bout With Cancer
Episode 40 · March 28th, 2013 · 32 mins 56 secs
About this Episode
Frank Macinsky is a young, healthy, and athletic community leader in Pittsburgh... who was diagnosed with cancer one year ago. This is the story of a guy who was both one of the luckiest and unluckiest 25 year olds in the entire country.
This story has nothing to do with haunted houses, but it has everything to do with friendship, positivity, and a truly life-changing experience. Clowns and zombies are not nearly as scary as chemo and mortality, but this story does have a happy ending.
Frank joins Laura Kelly and Margee Kerr for a look back at his "one year bout with cancer" in this episode of the ScareHouse podcast.
Frank Macinsky is the Director of Marketing for Thread, transforming waste in desperately poor countries into the most innovative products possible. For more information visit www.threadinternational.com.
ScareHouse, Pittsburgh's Ultimate Haunted House, has been ranked as one of "America's Scariest Halloween Attractions" by Travel Channel and featured in multiple online and print publications including USA TODAY, Forbes, AOL News, Yahoo, Funworld, and Money magazine.
Subscribe today for new episodes of our ScareHouse podcast. Help us reach new listeners when you leave positive reviews and feedback on iTunes. THANK YOU for your support!
Like ScareHouse on Facebook.
Follow ScareHouse on Twitter.
Watch ScareHouse on YouTube.


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Open-source software has been about two things: passion and need. The passion comes from developers' love of solving problems, creating new things and working with like-minded individuals. The need is about adding functionality to some existing software, or making a version of that software that is unencumbered (either free as in beer, or free as in speech, or both).
But today, a growing share of the open-source universe has been commandeered by large software organizations looking to commercialize an open-source project by offering proprietary add-ons, or through support and services. These companies—Oracle comes quickly to mind—might be seen as interlopers in the open-source community, viewing committers and contributors as nothing more than free (as in no cost) labor.
So, the question is: Are commercial open-source software and Free and Open Source Software at odds with each other, or is the relationship more symbiotic?
"I come down on the symbiotic side," said Tim Yeaton, president and CEO of Black Duck Software, which has software to help developers understand open-source code more clearly and to deal with license and intellectual property issues.
"[Black Duck] can identify 300,000 consumable, downloadable open-source projects, with 30,000 new projects begun every year. In the grand scheme, it works like it always did. Developers still find each other on interesting sites that are useful to them. Ninety percent [of those projects] never get a commercial entity around them. Analysts suggest that more open-source contributors are being paid by [commercial] organizations. It's not that the group of people who do it out of passion is shrinking; it's just that the former is growing."
Many experts agree that "professional open source" works best when a company comes in and respects the community that has grown around the project. "In the last decade, big vendors have consistently invested in open source for strategic business reasons, and they nurture the community for their interests," said Paula Hunter, executive director of the Outercurve Foundation, an advocacy that facilitates the participation of professional developers in open-source projects.
"Look at Eclipse. It was founded and funded by IBM with very tight control. Then it shifted to a non-profit governance model, and IBM loosened its control. Now, users and committers are more comfortable that the longevity of projects would remain intact and meet the needs of developers, rather than the commercial interests of IBM."
The issue of control over a project is a potential flashpoint for trouble, said Jim Jagielski, chairman of the open-source Apache Software Foundation. "In corporate environments, the list of requirements and features isn't derived from the need of the masses. It's derived from 'What can we sell?' At some level, companies have to give up control.


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A playful typographic experiment aimed at a pre-teen audience, brochure details the classes offered through the Creature Adventure summer camp for kids. For each week of attendance, the campers receive individualized certificates of completion that can be collected all summer. The accordion fold brochure is perforated at each spread, allowing the campers the opportunity to save the graphics from their favorite weekend as a keepsake.
Institution: Tyler School of Art
Art Direction: Soonduk Krebs


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Notes from Darrin Patrick, Lead Pastor of The Journey, St. Louis.
– Romans 1
– You are ruled by what you worship.
– 30% of the law dealt with idols.
– If you have a walking in the light problem or a loving people problem, you have an idol problem.
– An idol is anything other than God that you put in place of God..
– An idol is the sin beneath the sin.
– Lord, I trust you but…
– Most of the time we are clueless about our idols.
– The Holy Spirit exposes idols in our lives.
– idols hide deep in your heart.
– idols live in root sin.
– Idols are God substitutes or functional saviors.


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Handy Items for Water Photography
As the technology advances, photography goes with it. The creation of waterproof and high end cameras made water photography possible. That's probably the main reason why water photography is starting to get even more popular these days.
If you are one of those planning to take your amazing underwater shots, then it is important that you have the best idea about which what are the handy items that you need. Especially if you are travelling places to shoot. You need to make sure that you packed all the things that you need to have a successful water photography trip.
Water Photography
Of all forms of photography, water photography might be one of the most challenging one. Not only because you will need all the necessary equipment, but also because it would definitely be hard to shoot in the water, underwater especially. Since you would be dealing with water, you know for sure how difficult it is to find a scene or a subject to shoot unless you're a pro.
When it comes to water photography, there are some items and stuff that will come in handy. These items will help you have a stress-free and a smooth photography session. Because there's water involved, you need some water proof stuff. Except your camera, which should really be already made water proof or cased, you have to make sure that your other items are protected and dry. One important item that you should forget for water photography is the microfiber cloth. There would be a lot wiping and drying needed, that's for sure. That's when you also need an air blower to top it all.
You might also need to consider some tactical items. For instance, you might realize it, but using military grade watches will also help you with water photography. Especially for those who are going on places to shoot. Depending on which body of water you are planning to shoot, the things that you need will vary. For instance, shooting in the pool is far more different than taking pictures in a wide open ocean. In which will be challenging to do the other. That's when you need to consider your location too.
Safety is important
After getting all the right information about the items that you should bring, making a good list of them, you should be good. However, you certainly should not forget about safety. Since water photography is different from the usual photography sessions that you have, and water is isn't really a very safe place. You should think about you own safety at all times.
When it comes to safety, you would also need some stuff like wearing the right clothing, some safety gears like floaters, life jackets, etc. You need those to make sure that you're safe while taking photos. Wearing the right water clothing will also make you comfortable, thus, you will be able to take nice and amazing photos in the water.
Why to become a self-taught photographer?
All those photographers who have gone through their several years of photography have witnessed different types of assignments and with different mantras in order to enhance their photography skills. Most of the photographers feel that giving some amount of time is best tip for becoming a great photographer. It is an important aspect that photographers must know how to learn their skills from camera and understand the functions of their camera well. Go through every feature that your camera has and understand what effect and result it can bring into your pictures. Firstly try to use the functions of a simple camera and understand what other camera has different with the primary ones. Try to learn creativity and how to compose a shot that takes much more time than how to learn various types of control and functions. If you really want to become a photographer, here we present you some secrets that will help you out with becoming a self-taught photographer which is the best option for a photographer and how to become one:
- Always select a colour, shape and go for it: Take your camera and select a colour for a day. You must go out and click all the best objects and stuff that you can have using that colour. Make that colour a dominant element. Try to get different ways by which you can make it possible to do it. Later, select a shape and make that look great and different in your own way. You can use different shapes and any features of any artwork that you come across. Try to give it your feel and a different prospective by which people don't take it normally. Look for different combinations and you can highlight the shape that you have picked in your image.
- Try to capture something different an out of the box: If you go through some of the pictures of some famous photographers, you will see that they have played well with different designs, platforms, styles and shapes. Most importantly they have something new to show you every time due to which you find their picture very attractive. Try to pick a subject, and a different subject. If you have selected a regular subject, thing something out of the box and highlight a different angle of that subject. Change things as per your suitability. Get out from your comfort zone and see things and people around you in a different angle. Always remember that the image is the mirror of your perspective.
- Self-taught photography is independent: Self taught photography is a skill that is unique and independent in style. You can learn new tips and techniques using practice and thorough use of camera. You can also consult some of the experienced photographers. It will not only save your money on learning the skills properly but will also help you explore the world of photography through a different level. Go for more and more photo-shoots to understand the details of photography.


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Service provider difficulties in operationalising coercive control
Journal Article
Brennan, I., Burton, V., Gormally, S., & O'Leary, N. (2019). Service provider difficulties in operationalising coercive control. Violence against women, 25(6), 635-653. https://doi.org/10.1177/1077801218797478
We examined perspectives of social workers, police officers and specialist domestic abuse practitioners about their perceived ability and organisational readiness to respond effectively to incidents of coercive and controlling behaviour. Interviews r... Read More


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The final step in creating an active Fraud Policy is the assignment of the controls, rules and filters to a merchant account.
Step 1: Select the Assign Rules and Filters from the FBI Tools menu.
Step 2: Select the applicable Merchant Account.
Tip: to find the rule use the set of filters - Status, Assigned, Global Rule.
Step 3: Click the box next to the control, rule or filter being assigned.
Step 4: Click on Save.
Step 5: Click on Apply to all Merchant Account button to apply to all accounts.
Tip: To Cancel all changes prior to Save click Cancel.
User is able to mark any rule as Global by checking the appropriate checkbox and pressing Save button. After that the administrator will review this rule and approve it and it will become Global. Global rules can be assigned for other merchant companies by the administrator.
User can delete controls, rules and filters by clicking Delete button. Note, that user can delete rule created by himself and can not delete Global Rule, if it was created by admin or other users.


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This is a really cool and interesting topic to cover today as we move through the acronym: NEWSTART. Just to refresh, the letters all stand for something to do with health.
This blog is about TEMPERANCE. The dictionary defines the term as, "the espousal of moderation, marked by personal restraint. Upheld as a virtue."
Oh to have temperance! Restraint! Self control!
Basically the first idea is to completely abstain from what is always and only ever bad for you. Eg cocaine, nicotine or dare I say it, soft drink.
Secondly, moderate other things, by not having them to excess. This covers virtually anything else. Even "good" things.
Finally, make sure you include things that are good and necessary, eg: water and fresh vegetables.
The actual word that best fits here is an old fashioned word: "abstemiousness"
Abstemiousness is defined as, "Moderation in eating and drinking or the trait of avoiding excesses." However, it doesn't fit it the acronym, so temperance wins.
Excesses are fun at the time…and then…they are just not fun afterwards. No more fun to be had afterwards.
Being temperate in life across all areas is an excellent goal to have.
Balance, balance, balance.
Those with addictive personalities struggle a lot with this concept. The "all or nothing thinking" can be very detrimental. It goes like this, "well I have wrecked my healthy eating by having a piece of cake, so I may as well finish off the whole cake now." This is a catastrophic way of thinking and it won't serve you. Time to arrest it.
Most people who are fit and healthy have this trait of moderation working fairly well. It is a real secret weapon. For any of you who were taught to finish every single thing on your plate – even when you were not hungry, there is some work for you to do to retrain yourself.
Don't blame your folks.
I know you want to.
They had no idea though.
were just going with the flow of that era, even though it was not a
very evolved way to live. I remember as a little girl hearing about the
starving children in Africa, and why I should finish my dinner because
they did not have the food I had. I wished so so so hard they would just
come to my house…all the starving African kids…I would give them
EVERYTHING! I just did not want it, yet I had to eat it, for them,
somehow… which made no sense to me, even back then.
Now you know better so you can do better.
So to live temperately and moderately, it actually runs across many areas. Too much of anything is not good usually. Neither is leaving out what you should be including. That is also not good.
Do your best to incorporate these concepts into your own life.
Nutrition, Exercise, Water, Sunshine and Temperance.
Go forth and be temperate my dear ones.
For singing news, there are only a few YOU HAVE A VOICE hoodies left! Please don't miss out and make sure you get yours here before they are all gone. There are some great things in the Store, including great gift ideas. Have a look and see what you like.
The next INTRODUCTION TO THE RECORDING STUDIO workshop is on September 13th. Check the info here. Only a few spots left. You will love it. 100% positive feedback from every single person so far.
Also, please save the date! If you are in Sydney on the 5th October, please come along to the Manly Jazz Festival on Manly Corso, as I am a featured artist this year. Also, it is FREE!
Don't forget to let me know how YOU are.
Always remember, YOU HAVE A VOICE!


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Coho/US Board
Meet the committed, generous individuals who steer the Cohousing Association of the United States. We are always on the lookout for people who have time to commit to Coho/US, as well as a passion for community and cohousing. If you feel called to participate as a Board member, you can download the Board Application Packet. If interested, please send a completed application to president [at] cohous [dot] org. Thank you for your interest.
To see who has served on our Board (or as a staff member) in the past, click here.
Peter Lazar - PresidentMidAtlantic Region
Shadowlake Village (Blacksburg, VA)
Peter Lazar is active in the cohousing movement, giving talks on the subject and leading tours. He and his wife, Molly, are founders of Emerson Commons Cohousing, which is working to build a 26 home cohousing neighborhood near Charlottesville, Virginia. For the past 11 years, Peter, his wife, and their two daughters, aged 12 and 14, have lived in Shadowlake Village Cohousing in Blacksburg, Virginia. On the work-front, Peter is an award-winning technology entrepreneur, and has been involved in the Web since its inception. He received an MS in Computer Science from the University of Virginia in 1993.
Linda Herman - Vice PresidentWest Region
Lagunitas, California
Linda first dreamt of cohousing (even tho she didn't know that term) when she was 18, living communally in college in the wilds of Amherst, MA. She thought, "Wouldn't it be wonderful to grow old together with my friends, have a great house to gather in and have my own little place?" Who knew that decades later, she would pursue a 2nd career in design, that led her to become a development consultant with her own consulting firm, Linda Herman Consulting. Over the past 15 years, the firm has completed projects for religious institutions, non-profit organizations and senior cohousing communities. Her first senior-cohousing project in Oakland, Phoenix Commons, completed in 2016 and she is working with an organization in Portland on an innovative model for elder residential care blended with cohousing principles. Linda's education includes a B.S. from the Univ of Massachusetts/Amherst and B.A. in Interior Design from the Academy of Art College in San Francisco. Knowing she wanted to develop senior cohousing, she completed the Bay Area Ross Program in Real Estate, in association with the Lusk Center for Real Estate at USC. Linda is a certified Senior Co-Housing Facilitator, and LEED-Accredited Professional. In her spare time, she dances, hikes and gardens in lovely west Marin County, CA.
Jim Leach - Vice PresidentMountain Region
Silver Sage Village, Boulder, Colorado
Jim Leach is president of Wonderland Hill Development Company and has lead the company in
Ty Albright - TreasurerSouthcentral Region
Carrollton (suburb of Dallas), Texas
Ty Albright is an Artist, Gardner, and Theologian with 30+ years' experience in Commercial Real Estate; most of it with GE Capital Commercial Real Estate. He lives in Carrollton (Dallas) Texas. Ty is a graduate of Katie McCamant's 500 Communities program and is a trained Cohousing Development Professional. He works as a real estate Project Manager for various projects and is currently involved with development of low cost community neighborhoods in rural (Sulphur) Oklahoma for people who want to down shift their lives to an affordable location. He is also a licensed Texas Real Estate Broker. Currently in the USA we have a large demographic shift with retiring baby boomers who need living solutions for their next phase of life. Ty understands alternative housing solutions and living strategies including the emerging "downshifting" and "right shifting" lifestyle choices. Contact Ty: ty [at] texascohousing [dot] info www.linkedin.com/in/tmalbright 214-336-7952 texascohousing.info
Alan O'Hashi - SecretaryMountain Region
Silver Sage (Boulder, Colorado)
I have a diverse professional background beginning with a career in city and tribal management and land use planning in Wyoming. After moving to Colorado my interest evolved into nonprofit fund development, including several years building Habitat for Humanity homes. I also served a term on the city of Boulder Planning Board and recently completed a stint on the Boulder Affordable Housing Working Group. After being laid off a job I grew tired of working for marginally competent bosses, and took some production classes at the local public access TV station and am now Executive Director at Back Country Media and haven't looked back. I'm currently producing two documentaries about cohousing - having lived at Silver Sage Village for six years. I look forward to helping move cohousing into the mainstream.
Mary Kraus - Board MemberNorth East
Pioneer Valley (Amherst, MA)
Mary Kraus, AIA, LEED BD+C is a cohousing architect and facilitator who has worked with over two dozen communities in the US and Canada over the past thirty years. She was a founding board member of the Cohousing Network (now Coho US). She would like to expand cohousing in this country, so that more people can enjoy this way of living and find ways to support communities to thrive. She lives at Pioneer Valley Cohousing, the first cohousing community in the eastern US, where she can be found preparing dinner in the common house kitchen with her cook team.
Steven Ablondi - Board MemberInternational
Memel, South Africa
Steven Ablondi is creating senior cohousing as a promoter and developer in Memel, a town in the Drakensburg mountains of South Africa. He feels much can be done to reduce the amount of time necessary to create cohousing communities and has purchased land, received municipal permits and planted organic gardens and orchards for clusters of homes to be built with natural materials and using alternative energy. Steven has had field assignments with the United Nations in Cambodia, Bosnia and Angola. He is a graduate of the Northfield Mt. Hermon School, Wesleyan University and Vermont Law School. He makes his home with his wife on Lake Champlain in America and in the Memel Drakensburg in South Africa.
Ann Lehman - Board MemberNorthwest Region
PDX Commons (Portland, Oregon)
Annie, raised on the East Coast, has worked in the public interest arena for more than 35 years as a lawyer, executive director and community organizer. She started her career running a storefront legal office in Portland, Oregon geared to seniors. Annie, with her late husband, started Zimmerman Lehman, a consulting group assisting nonprofits in forging sustainable futures. For 20 years, she worked as a policy specialist on gender equity for the City of San Francisco. When not off hiking and exploring, she continues as principal of Zimmerman Lehman. She recently returned to Portland to help in forming PDX Commons, a senior cohousing due to open April 2017, fulfilling her long-standing dream to live in an intentional community.


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Tom Schulte is the nephew of one of the crew of Heavenly Body II the B17 that crashed off the Point at Canvey. His uncle Louis died in the crash, his body was found at Southend Pier.
Janet Walden, Dave Thorndike and I met with the Schultes at the B17 information board where we took some photos. We then showed them the Mural. We went on to the War Memorial where the original memorial to the B17 crash is situated. Here Tom was given a cross to place near the plaque.
Janet and I had to leave them then as we had a meeting to attend but Dave Thorndike took them onto the Bay Museum to see some of the artefacts there from the plane. I believe a small piece of the wreckage was given to Tom.
The couple had already spent Saturday and Sunday with Geoff Burke visiting Kimbolton, Madingley Cemetery and the USAAF Museum at Duxford.
They fly home on Friday. Come back soon.
Janet Walden and Dave Thorndike with Tom and Linda Schulte
J Penn
Tom pointing to his uncle in the mural
Linda and Tom at the War Memorial
I spent WW 2 on Canvey Island and witnessed the collision of the two B17's. I got a tremendously proud feeling as I viewed the article above. Proud for the British people and especially Canvey Islanders together with our great Archive site members. Tom and Linda Shulte will return home, I'm sure, with very complimentary words about the Memorial and all other materials assembled in memory of those brave American airmen, and with reference to Tom's Uncle. Congratulations to all connected with this very important project.
Canvey Island Archive > http://www.canveyisland.org/
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Chinese firms start to cut jobs and move overseas as US trade war and rising costs start to bite
Thursday - 18/10/2018 09:22
Once-booming smaller and medium-sized businesses start to feel the squeeze from rising costs with US tariffs set to make the situation worse
Chinese firms start to cut jobs and move overseas as US trade war and rising costs start to bite
Yang Xiaoying feels conflicted and overwhelmed by the uncertain future of the factory she and her husband founded 15 years ago in Dongguan, a manufacturing hub in southern China.
To offset the impact of shrinking orders and soaring operational costs for the factory, which produces shoes and leather accessories for overseas buyers, she has been forced to downsize her workforce from over 200 last year to about 150.
Xie Xusheng, who owns a garment making and embroidery processing factory in the city, also laid off about 160 workers soon after he opened a new factory in Vietnam's Ho Chi Minh City early this year to supply big-name American brands with shoes, bags and accessories.
He only kept on about 40 senior skilled workers at his plant in Guangdong province for complicated sample development.
The decisions by Yang and Xie to cut workers are part of a subtle but growing trend of smaller Chinese firms cutting their employment levels in an effort to allow their businesses to survive.
Small businesses are increasingly struggling with shrinking foreign orders due to US tariffs, a depreciating yuan that raises the cost of imported materials and soaring domestic costs for energy, taxes, rent and labour.
This year, the number of lay-offs at small and medium-sized manufacturing firms, tech start-ups and financial organisations has grown at a double-digit rate in percentage terms, according to industry analysts.
The situation threatens to get worse, given the escalating trade war with the US.
Washington has slapped 10 per cent duties on US$200 billion of Chinese imports effective from Monday, with the tariff rate set to rise to 25 per cent on January if Beijing does not make concessions.
US President Donald Trump has also threatened to levy tariffs on the remaining US$267 billion in Chinese imports not already sanctioned.
China's official unemployment rate has hovered between 4 and 5 per cent for decades, though many domestic and international analysts believe the government data does not accurately reflect the worsening unemployment situation because official statistics do not take into account unregistered jobless and surplus workers in rural areas.
According to the CIER index, designed to monitor changes in China's labour market, employment at small and middle-sized firms has fallen far this year, with the decline accelerating in the second quarter.
A CIER index score of greater than one indicates that the labour market is improving, with more jobseekers than available vacancies, while an index below one indicates the labour market is deteriorating.
The CIER index for small (20 to 499 employees) companies fell from 0.85 in the first quarter to 0.79 in the second, indicating accelerating lay-offs. The index for medium-sized companies (500 to 9,999 employees) fell from 1.01 to 0.97, indicating that they too were beginning to cut workers.
Yang said the lay-offs would help to lower her labour costs from about 700,000 yuan (US$102,000) per month to about 500,000 yuan, which would help offset the firm's soaring expenses for raw materials, rent and employee social security.
She also hinted that there were likely more lay-offs to come, saying: "Actually, there aren't enough orders [now] to sustain 200 workers."
Yang and her husband moved to Dongguan from the eastern province of Jiangxi to start their small workshop in 2003 when labour and raw materials were dirt cheap.
With a steady stream of orders from America, Europe and Hong Kong, the workshop expanded to become a factory of 800 full-time and part-time workers at its peak in 2008.
"But then we had to downsize, first because of a labour shortage in the early 2000s, now because of weaker demand for Chinese goods from overseas buyers," Yang said.
"So far, shoes accessories are not on the list of [of products subject to] extra tariffs. But we all believe they will be included sooner or later."
Xie said: "We are seeing more and more small and medium-sized [contract manufacturing] factories that cannot withstand the double hits resulting from US tariffs and higher payments for employees' social security, forcing them to downsize.
"Many export-oriented factories here have seen orders cut in half."
Xie said he made his decision to move most of his production to Vietnam after his biggest customer moved his supply chain to Southeast Asia.
"A growing number of Chinese textile and garment suppliers are setting up factories in Vietnam and Cambodia because overseas customers are increasingly placing orders only from factories in these countries, instead of China," he said. "That's why I had to follow and set up a plant there. "
The foreign brands that are Xie's main customers "used to source from 25 Chinese suppliers on the mainland, but now are partnered with just two because of worries about [US] tariffs".
Employment downsizing is also occurring at tech start-ups and private financial services companies.
"Our Guangzhou branch just downsized from 600 to 200 employees, with all [employees in the] logistics and administrative departments cut, because of the weak performance of financial funds and the stock market this year," said a senior sales manager at a private financial capital company who refused to disclose his company's name.
"Senior executives were required to take a basic salary pay cut of 30 to 70 per cent," he said.
The job situation at small and medium-sized financial firms was gradually worsening due to the steady deterioration of country's informal shadow banking system, on which many smaller firms relied for capital, and the continued decline in the stock market, the manager said.
"Investor confidence is lower than ever before because of the economic slowdown that the trade war is causing."
Jonathan Yu, the founder of a new app company in Guangzhou, said tech start-ups were also facing a hard time. "The whole venture capital sector is becoming very cautious about investing," he said.
In August, China's national tax authority told local governments to stop offering tax incentives to venture capital firms as the country revamps its tax policy in response to slowing economic growth. Venture capital firms now should pay a progressive tax rate of 5 to 35 per cent, rather than the 20 per cent flat rate they have paid previously in many areas.
"If implementation of tax polices gets stricter, it would a big blow to the tech sector," Yu said.
All the people spoke to agreed US tariffs would put increasing pressure on their sectors, resulting in many more people losing their jobs at once-booming businesses.
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In Honor of our beloved Oscar who lost his battle yesterday to this disease
Thank you for what you do
In memory of Miss Bean, FIP Warrior
Hope they find a cure for this awful disease!
Just a little something for this wonderful cause... Thank you!!!
This donation is in loving memory of Olivia Elliott whose story appears on your FIP Fighters page. A cure cannot come soon enough.
In memory of Nanachi, a street warrior full of love
🐾 indicates repeat donations
Jennie Anderson 🐾🐾
11 fat cats
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Jill Barone 🐾🐾
As always, in honour of my dear Odin and Loki. Forever in my heart. xxx
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Thank you for everything you do to help fight FIP.
Susanne Blanck 🐾🐾
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Thank you for what you do
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Tucker's Mom
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For Ally and Shiloh
Lee Yang Cheng 🐾🐾
In memory of Nanachi, a street warrior full of love
Danielle & Adrian Cocos 🐾🐾
This donation is in honor of Leela, we pray that we can help make a difference in finding a cure to FIP so less families have to experience the loss of their fur babies and that the kitties can have a chance at life.
Karin Coles 🐾🐾
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Please save my t-shirt for someone else. I'm just happy to donate without needing for anything in return
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After losing our two kittens to FIP in such a short amount of time, we are heartbroken and no family should have to lose their fur baby to such a horrible, fatal disease. Grateful for what you are doing, thank you.
Brock Dumont 🐾🐾
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FIP Warrior Clove
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In memory of our sweet Leela, our FIP Warrior. You will always be in our hearts.
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After the loss of two kittens I want nothing more than to see the end of this horrible virus called FIP! Thank you for all you are doing! Lorraine
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In baby Echo's memory
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a small monthly donation to help fund the research for a cure, lets hope that breakthrough is soon!
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I pray one day you find a cure for this silent killer
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Memory of Gracie
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In memory of Miss Bean, FIP Warrior
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Thanks, Peter, for continuing to ask for money. You have plucked my heartstrings and found another donor. Marci
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My husband and I just lost our baby girl Mochi to wet FIP on 9/12/19. We are so devastated and still in shock. We want to help this foundation and help raise more awareness for this awful disease. Please let us know what else we can do to raise awareness and advocate for all the FIP warriors out there. We want to honor our little Mochi.
Laura Carina Martinez 🐾🐾
Thank you for your dedication to cats.
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Continue to be strong our FIP Warrior Smokey!
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Our sweet baby JuJu passed away in August 2018 at just four months old... we only had him for six weeks and miss him everyday... this disease is very close to our hearts and we're happy people are working hard to find a cure.
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Cocoa Nagoya
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The Kitangle Krew is happy to be fighting FIP!
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In memory of my FIP Angels Matilda and Aussie
James Park🐾🐾
I hope this will help your research
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Vivipet INC 🐾🐾
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FIP is such a cruel illness. I have lost my little Yuri recently. He was one year old. I am happy to see Smokey alive.
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Kate Richards 🐾🐾
Jamison & Debra Roberts 🐾🐾
Our Luna is proof that UCD is on the edge of a cure for FIP...but funding is necessary to convince the drug companies to manufacture the drug that Luna is on (and the one before it.) . Please consider a recurring monthly donation.
Christie Russell 🐾🐾
In memory of my Peanut
Danielle Sauers 🐾🐾
Lorelei Von Schilling 🐾🐾
Joe Semonelli 🐾🐾
Thanking UC Davis Veterinary College for being the leaders in the fight against FIP.
For Tucker. From his brothers Blue and Bugsby.
Joy Smilth 🐾🐾
Kayla Stoker 🐾🐾
For Julius. I miss him everyday
Amy Talmadge 🐾🐾
Hanmei Tang 🐾🐾
Jeffyne Telson 🐾🐾
Good work!
Sylvia Torres 🐾🐾
For my girl Emily
Milagros Viquez 🐾🐾
I lost my Tucky Tuck 13 months ago and I miss him with every fiber of my being. I can't wait to be reunited with him one day. FIP is one of the most heartbreaking diseases ever. Right now I can donate this much but once I finish this financial rough patch, I will donate much more. Thank you for the work you do. Thank you so much. My Tuckums is gone but if it saves another family from this type of devastation, if at least a few more cats like Smokey can lead a longer, happier more fulfilling life, that is all that matters. Thank you!
Tiffany Wall 🐾🐾
To Peanut, Lily, Romeo, Willow, Blossom, Simba & Nala forever in my hearts
Dee Watt 🐾🐾
Emilia Waszkielewicz 🐾🐾
For Irene - my little FIP fighter and the bravest soul I know
Brittany White 🐾🐾
Ying Wu 🐾🐾
In memory of Drew
Justin Yoffe 🐾🐾
Alison Zuber 🐾🐾
Amisha Zuber 🐾🐾
Sierra t Zuber 🐾🐾
Yoshiaki Aburaya
Shawn Aller 🐾
Glad to donate to find a cure.
Porter & Anita Abbott🐾
Barbara Abbott
As you are a super lover of cats, this birthday donation has been made in your honor & with love from Porter & Anita
Ruriko Akasaka
I hope you can find a cure and Smokey survive from FIP.
Christine Bagetakos
Claudine Baggetto
Hobbes Berlingieri
Peter Booth
This is for Freyja who is still with us.
Jody Boyman
Jeremy Brownstein
Lost our beloved cat to FIP! Thanks for all your work. :)
Justin Buckner
I'm glad I can be a part of making a difference toward helping to find a cure against FIP! :)
Oliver Bundy
My roommate picked up a kitten off the street and we all fell in love with her. She's been with us for a few months and she's the sweetest kitty in the world. She cuddles with everyone, even the dog. She's had medical problems ever since she came here and we recently found out she might have FIP. Her blood is getting tested and we'll hear the results soon. I've been looking into FIP and found you guys. I really hope you guys can cure this sickness so other cats don't have to suffer
Michelle Bryant
Shelley Bryant
Carol Byrne
Sorry for the small amount (and the weird amount). Love seeing the pics and videos of your cats!
Margo Caigoy
June Calcutt
Crystal Callans
Maureen Camfield 🐾
One day there will be no more suffering. RIP sweet Percy, until we play kiddening, buggies, and birdies with you again.
Ruth Cartledge
In honor of Susan Leroy, and in memory of Angeltree Tri-wizard Flitterby AKA Flitter
Lydia Corona-Craig
Ben Cohen
Good luck:).
Jon Cohen
Kellie Kennedy-Cohen
Peter Cohen 🐾
In honor of Miss Bean
Karin Coles 🐾
Amy Cooper
Laurie Crasnick
Destiny Crary
Jeanne Dams
Sabrina Daugherty
Amy Deese 🐾
Very happy to contribute to this research and hoping a cure can be developed.
In honor of Queen Alexa
Nicole Dey
Hilary and Linda Dozer
Linda Dragavon
Brock Dumont
Jeff Dutcher
Susan Elliott
This donation is in loving memory of Olivia Elliott whose story appears on your FIP Fighters page. A cure cannot come soon enough.
Courtney & Dustin Evans 🐾
This donation is made in loving memory of our baby boy, Rocket. We had such a short time with him, but he has impacted our lives in such a loving and purrfect way. Always in our hearts.
Elaine S. Ewen
Chrystal Fanelli
Dana Faletti
We just lost our 5 month old precious kitten, Bily Fluffy Faletti (BFF) to FIP. This donation is in his name.
Emily Farr
Carrie Froseth
My baby boy Iscar died of FIPs many years ago. I miss him so much. Thanks for your work!
Hiroyuki Furumoto
Thank you for helping the FIP research
Julie Garcia
Janice Garrett 🐾
Ryan Geithman
In honor of Smoke, a six month old FIP Warrior
Gewls Gentile
Marian Getz
Best wishes finding a cure!
Susan Gingrich 🐾
Maggie Gobat
Cyndi Gust
Hope they find a cure for this awful disease!
Kathy Guthrie
Nancy Hansen-Aguirre
Kelly Harris
Karen Hart
Mirian Hasani
just a little something for this wonderful cause... Thank you!!!
Michelle Heart
Julie Heiser
For little Marlowe
Diane Himes
Duncan Holbrook
Bunni Hopper
I love your desire and drive to help these sweet cats.
Dailene Hudson
Our daughter-in-law, Martyna Hudson, requested her birthday gift be a donation to your organization
Heather Hudson
In Memory of Irene Waszkielewicz. Donated for Tynka's birthday!
Rebecca Husmann
FIP Warrior Cat Sasha
Mary Ingram
Lost my cat, Bubsy, to FIP in 2014. He was 2 years old. One of the most heart-breaking losses I've been through. Hope this can help so fewer folks and cats have to go through that.
Cyndi Jukowski
Thank YOU for all you do in the fight against FIP, Peter!
Doralee Jacobson
Eric Johnson
We are fortunate that Basil has beaten FIP with GC376. Hoping and praying that his FCoV positive siblings; Ashley, Bentley, and Natasha never develop FIP. An affordable and widely available cure must be developed as soon as possible. Thank you for all of your efforts, Peter.
Jennifer Jones
Please put a end to dreadful FIP, had way to many die with it. (more wet than dry). Thank you.
Young Kil Jung
Hargita Kaplan
I lost my Gracie girl to FIP three years ago this April 30th. I miss her every single day. She was diagnosed with Dry FIP not long after her spay. Similar to Miss Bean, she just never got her energy back and had eye issues. Gracie was a week away from starting her experimental treatment at UC Davis when she passed. She was our special sphynx baby who will never be forgotten. Thank you so much for doing what you do and for sharing your stories!
Anna Kat
Bob Katz
Lorraine Keane
Colleen Kelly 🐾
Jim Kennedy
Bo Khine
In honor of Pluto, currently fighting FIP and planing to win
Alexandra Kibilko
My cat passed last Wednesday of FIP, he had the wet form, and we didnt find out until it was too late. Please, do anything you can to help cats in the future avoid suffering from this horrible virus... He was my baby
Kylie Kiel
Ingo Koch
Christine Kopitzke
Denise Kornblatt
Spreading the love for FIP research and ZenByCat
Michael Kostka
Ruslan Lagutin
Josh Langdon
In Honor of our beloved Oscar who lost his battle yesterday to this disease
Linda Langdon
In Honor of our beloved Oscar who lost his battle yesterday to this disease
Mavis Leahy
In honor of Michelle Waters B day
Holly Lepere
Bruce LeToumeau
Nine and 1/2" Lives Cat Rescue
Pak Man Leung
In memory of Terra(27/10/2018)
Joanna Li
for research to make a cure available. We lost our beloved cat last week to FIP and do not ever want to see more cat owners lose their cats to this awful disease. Thank you for all that you do
Louis Linden
Kelly Lopes
For Smokey, from your Wrigley Kittens friends. Praying that love and science come together and bring us a miracle!
Susan LeRoy 🐾
In support of FIP research and in honor of Jeffyne Telson's birthday.
Thank you for going above and beyond to help Miss Bean and to support finding a cure for FIP.
Please accept my donation of $100 in honor of Jeffyne Telson's birthday this past October 15, 2017.
Fergus Lo
Kelly McHugh Lopes
On behalf of my friend and kitty-loving friend Brandyce Howard. Thanks to her for trusting me with her real estate transactions this year, and thank you for the tireless work you do to help end FIP.
The Maness Family
Paula Matthews
Thank you for your dedication to cats.
Ashleigh Marvin
Marisol Mayell
Elizabeth Maxwell
Keep working to save kitties' lives.
Tammy McCarthy 🐾
To Smokey. Keep Fighting!! With love, Tammy
Trent McPheron
For Ozzy:)
Joseph McRobert
Please find a cure soon!
Laura Messa
Stef Miller
Kyle Molee
Peter Moran
Hope this donation helps in the research for a cure!!!!!
Valerie Moreno
Susan Morris
Walt Morris
Crystal Moudy
Jung Maylee Oddo 🐾
Brandon Parker
Elizabeth Perry
Wishing for a cure!
Martha W. Perry
Dante Pettis
I am donating the value of one FerrisCatWheel from ZiggyDoo
Janine Raney
I lost my Yoshi to FIP. Time to end this disease.
Nadine Piontka
Safe and peaceful journey Poppyseed
Lovorka Prpic
Mallory Rabold
I recently lost my 10 month kitten Woody to the wet form of FIP. I am absolutely shattered. I will donate as much as I can as often as I can.
Bob Ralston
In memory of my beloved tabby named "Possum" who died of hyperthyroidism just before her 15th birthday
Morgan Renken
Bren Rivers
Linda Robyn
Kathy Roy
Mary Rubin
This is in the name of a little cat named Toby in San Jose, Ca that just succumbed FIP yesterday. Devastating.
Deborah Russell
Elizabeth Saavedra-Bayat
Happy to support the cause!
Sue Sadler-Pare
Donation by the Estate of Spencer H. Sadler, for his love of All Creatures Great and Small
Renee Sanborn
Blanca Sanchez
Daniela Scherner
Gal Schkolnik
Caroline Sereyko
In honor of Mila and all the FIP kitties we weren't able to save at my shelter
Sandy Simmons
Marie Sirotniak
Thank you for the work that you are doing. My friend sent me a video she saw on Facebook (I don't do Facebook). But I DO love folks that are making a life changing difference for cats. My pleasure to donate a little.
Diane Smith
Annihilate FIP!
Susan Smith
TL Sol
Lindsey Stasko
Naomi Tanaka
Thank you
Demi Taylor & Matthew Busch
Here to find the cure for FIP
Tiffany & Cat
My cat Mr. Pickles passed away this past Christmas from FIP & I would love to find a cure so people like me don't ever have to experience of the loss of a feline baby. He was only 11 months old & was the best kitty ever. Thank you for your dedication to finding a cure.
Judy Tran
The Team at Trillium Enterprises
We stand with you in the fight against FIP
Jeffyne Telson 🐾
My birthday gift to the cats and to you my friend. :)
Ben Traverso
Gabriel Janse Van Rensburg
Peter Winn
Sean Yeager-Diamond
Janina Waszkielewicz
In memory of Irene Waszkielewicz
Penny Westberry
Linda Wilson
Ronelle Wilson
Beth Winser
In honor of our baby boy Baxter who's life was too short. I pray there is a cure soon.
Alison Zuber
Liubov Zvereva
Hycomb Marketing
Thank you for inspiring us daily.
Snuggly Cat


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