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If you want to track how close we are to the next financial collapse, there is one number that you need to be watching above all others. The number that I am talking about is the yield on 10 year U.S. Treasuries, because it affects thousands of other interest rates in our financial system. When the yield on 10 year U.S. Treasuries goes up, that is bad for the U.S. economy because it pushes long-term interest rates up. When interest rates rise, it constricts the flow of credit, and a healthy flow of credit is absolutely essential to the debt-based system that we live in. Just imagine someone squeezing a tube that has water flowing through it. The higher interest rates go, the more economic activity will be squeezed. If interest rates continue to rise rapidly, it will be more expensive for the U.S. government to borrow money, it will be more expensive for state and local governments to borrow money, the housing market may crash again, consumer debt will become more expensive, junk bond investors will be in for a world of hurt, the stock market will experience a tremendous amount of pain and there is a good chance that we could see the 441 trillion dollar interest rate derivatives bubble implode. And that is just for starters.
So yes, we all need to be carefully watching the yield on 10 year U.S. Treasuries. On Friday, it opened at 2.76% and hit a high of 2.86% before closing at 2.83%. The yield on 10 year U.S. Treasuries is up nearly 120 basis points since the beginning of May, and almost everyone on Wall Street seems convinced that it is going to go much higher.
We are truly moving into unprecedented territory, because we have been in a bull market for U.S. Treasuries for the last 30 years. Many investors don't even know that it is possible to lose money on U.S. Treasuries. They have been described as "risk-free" investments, but that is far from the truth.
In fact, we could see bond investors of all types end up losing trillions of dollars before it is all said and done.
And those in the stock market will lose lots of money too. Low interest rates are good for economic activity which is good for the stock market. The chart posted below shows that stock prices have generally risen as the yield on 10 year U.S. Treasuries has steadily declined over the past 30 years…
When interest rates rise, that is bad for economic activity and bad for stocks. That is why so many stock analysts are alarmed that interest rates are going up so rapidly right now.
And as I wrote about the other day, we have just witnessed the largest cluster of Hindenburg Omens that we have seen since before the last financial crisis. The stock market already seems ripe for a huge "adjustment", and rising interest rates could give it a huge extra push in a negative direction.
By the time it is all said and done, stock market investors could end up losing trillions of dollars in the next stock market crash.
In addition, rising interest rates could easily precipitate another housing crash. As the Wall Street Journal discussed on Friday, as the yield on 10 year U.S. Treasuries goes up it will also cause mortgage rates to rise…
Higher yields will push up long-term borrowing cost for U.S. consumers and businesses. Mortgage rates will rise, and investors are keeping a close eye on whether this may derail the recovery of the housing market, which has shown signs of turning a corner this year.
In one of my previous articles, I included an example that shows just how powerful rising mortgage rates can be…
A year ago, the 30 year rate was sitting at 3.66 percent. The monthly payment on a 30 year, $300,000 mortgage at that rate would be $1374.07.
If the 30 year rate rises to 8 percent, the monthly payment on a 30 year, $300,000 mortgage at that rate would be $2201.29.
Does 8 percent sound crazy to you?
It shouldn't. 8 percent was considered to be normal back in the year 2000.
If you own a $300,000 house today, do you think it will be easier to sell it or harder to sell it if mortgage rates skyrocket?
Yes, of course it will be much harder. In fact, there is a good chance that you will have to reduce your selling price significantly so that prospective buyers can afford the payments.
Let us hope that the yield on 10 year U.S. Treasuries levels off for a while. If it says at this current level, the damage will probably not be too bad.
But if it crosses the 3 percent mark and keeps soaring, things could get messy pretty quickly. In fact, according to a Bank of America Merrill Lynch investor survey, the 3.5 percent mark is when the collapse of the bond market is likely to become "disorderly"…
Our latest Credit Investor Survey, conducted July 8-11, showed that 3.5% on the 10-year is most commonly thought of as the trigger of a disorderly rotation – i.e. higher interest rates leading to outflows and wider credit spreads – among high grade investors.
Put differently, 3.0% on the 10-year will not lead to overall wider credit spreads if there is enough buying interest from institutional investors (though note that the 10s/30s spread curve would flatten further, as mutual fund/ETF holdings are concentrated in the belly of the curve, whereas institutional demand is disproportional in the long end of the curve). However, if the probability of a further move higher in interest rates to 3.5% is high – which will be the perception if interest rate volatility is high – certain institutional investors will choose to remain on the sidelines.
Thus there may not be enough institutional buying interest to mitigate retail fund outflows and contain overall high grade spread levels.
So what is causing this?
Well, there are a number of factors of course, but one very disturbing sign is that foreigners are selling off U.S. Treasuries at a pace that we have not seen since 2007…
One of the biggest fears in the financial markets is that foreign investors will stop buying U.S. Treasury securities, causing borrowing rates to surge.
Not that this is the beginning of a frightening trend, but new data from the Treasury Department shows that foreigners were net sellers in June. In fact, this is the largest net sale of U.S. securities since August 2007.
Do you remember all of the warnings that we have received over the years about what would take place when foreign countries started dumping U.S. debt?
Well, it looks like it may be starting to happen.
Unfortunately, there is no way that the party that the U.S. government has been throwing can continue without foreigners buying our debt. We have added more than 11 trillion dollars to the national debt since the year 2000, and according to Boston University economist Laurence Kotlikoff we are facing unfunded liabilities in future years that are in excess of 200 trillion dollars.
Even with foreigners continuing to loan us gigantic mountains of super cheap money, it would still take a doubling of our taxes to put us on a fiscally sustainable course…
Writing in the September issue of Finance and Development, a journal of the International Monetary Fund, Prof. Kotlikoff says the IMF itself has quietly confirmed that the U.S. is in terrible fiscal trouble – far worse than the Washington-based lender of last resort has previously acknowledged. "The U.S. fiscal gap is huge," the IMF asserted in a June report. "Closing the fiscal gap requires a permanent annual fiscal adjustment equal to about 14 per cent of U.S. GDP."
This sum is equal to all current U.S. federal taxes combined. The consequences of the IMF's fiscal fix, a doubling of federal taxes in perpetuity, would be appalling – and possibly worse than appalling.
Prof. Kotlikoff says: "The IMF is saying that, to close this fiscal gap [by taxation] would require an immediate and permanent doubling of our personal income taxes, our corporate taxes and all other federal taxes.
"America's fiscal gap is enormous – so massive that closing it appears impossible without immediate and radical reforms to its health care, tax and Social Security systems – as well as military and other discretionary spending cuts."
Can you afford to pay twice as much in taxes to the federal government?
Very few Americans could.
But that is how serious the financial problems of the federal government are.
And all of the above assumes that interest payments on U.S. government debt will remain at current levels. If the average rate of interest on U.S. government debt rises to just 6 percent, the U.S. government will be paying out a trillion dollars a year just in interest on the national debt.
Also, all of the above assumes that we will have a healthy financial system that does not need to be bailed out again.
But if rapidly rising interest rates cause the 441 trillion dollar interest rate derivatives bubble to implode, the bailout that the "too big to fail" banks will need will likely be far, far larger than last time.
In fact, once that bubble bursts there probably will not be enough money in the entire world to fix it.
If the picture that I have painted above sounds bleak, that is because it is bleak.
Sometimes I get frustrated with myself because I don't feel I am communicating the tremendous danger that we are facing accurately enough.
We are heading for the worst financial crisis in modern human history, and the debt-fueled prosperity that we are enjoying today is going to go away and it is never going to come back.
You can dismiss that as "doom and gloom" and stick your head in the sand if you want, but that isn't going to help anything. Instead of ignoring reality you should be working hard to prepare your family for what is coming and warning others that they should be getting prepared too.
When a hurricane is approaching landfall, you don't take your family out for a picnic at the beach. That would be foolish. Unfortunately, way too many Americans are acting as if nothing like the financial crisis of 2008 could ever possibly happen again.
If you deceive yourself into thinking that all of this is going to have a happy ending somehow, you are going to get blindsided by the coming storm.
But if you make preparations now, you might just be okay.
There is hope in understanding what is happening and there is hope in getting prepared.
So watch the yield on 10 year U.S. Treasuries. The higher it goes, the later in the game we are.


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Erin Entrada Kelly
Lalani of the Distant Sea
Non-Fiction / Reference
Only 1 left in stock
Product details
Lalani of the Distant Sea
"Fast-paced and full of wonder, this is a powerful, gripping must-read."—Kirkus (starred review)
"A lush and mysterious fable, full of beauty, full of wonder."—Rebecca Stead, Newbery Medal–winning author of When You Reach Me
Newbery Medalist Erin Entrada Kelly's debut fantasy novel is a gorgeous, literary adventure about bravery, friendship, self-reliance, and the choice between accepting fate or forging your own path.
When Lalani Sarita's mother falls ill with an incurable disease, Lalani embarks on a dangerous journey across the sea in the hope of safeguarding her own future. Inspired by Filipino folklore, this engrossing fantasy is for readers who loved Grace Lin's Where the Mountain Meets the Moon and Disney's Moana.
Life is difficult on the island of Sanlagita. To the west looms a vengeful mountain, one that threatens to collapse and bury the village at any moment. To the north, a dangerous fog swallows sailors who dare to venture out, looking for a more hospitable land. And what does the future hold for young girls? Chores and more chores.
When Lalani Sarita's mother falls gravely ill, twelve-year-old Lalani faces an impossible task—she must leave Sanlagita and find the riches of the legendary Mount Isa, which towers on an island to the north. But generations of men and boys have died on the same quest—how can an ordinary girl survive the epic tests of the archipelago? And how will she manage without Veyda, her best friend?
Newbery Medalist and New York Times–bestselling author Erin Entrada Kelly's debut fantasy novel is inspired by Filipino folklore and is an unforgettable coming-of-age story about friendship, courage, and identity. Perfect for fans of Lauren Wolk's Beyond the Bright Sea and Kelly Barnhill's The Girl Who Drank the Moon.

subset: commoncrawl


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As far as I know, Harvard Law School's employment numbers are strong enough that there's no need for it to play games. That said, you have to wonder how tempted HLS is to take advantage of the most famous member of its graduating class -- that being John Cochran, aka the winner of "Survivor: Caramoan."
Of course, Cochran isn't even the only winner with a JD (technically, I don't think he's been awarded his JD yet); Yul Kwon, who won "Survivor: Cook Islands," has a JD from Yale.
Anyway, Cochran also has a job already . . . as Entertainment Weekly's "Big Brother" recapper. Hmm, as far as I know, "Big Brother" only airs in the summer, so will Cochran still count as employed 9 months after graduation? Then again, winning "Survivor" and the $1 million has got to count somehow, right?


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West Nile virus causes a viral disease and is spread by mosquitoes. The condition ranges from mild to severe.
West Nile virus was first identified in 1937 in Uganda in eastern Africa. It was first discovered in the United States in the summer of 1999 in New York. Since then, the virus has spread throughout the US.
Researchers believe West Nile virus is spread when a mosquito bites an infected bird and then bites a person.
Mosquitoes carry the highest amounts of the virus in the late summer and early fall, which is why more people get the disease in late August to early September. As the weather becomes colder and mosquitoes die off, there are fewer cases of the disease.
Although many people are bitten by mosquitoes that carry West Nile virus, most do not know they have been infected.
Risk factors for developing a more severe form of West Nile virus include:
- Conditions that weaken the immune system, such as HIV/AIDS, organ transplants, and recent chemotherapy
- Older or very young age
- Pregnancy
West Nile virus may also be spread through blood transfusions and organ transplants. It is possible for an infected mother to spread the virus to her child through breast milk.
Symptoms may occur 1 to 14 days after becoming infected. Mild disease, generally called West Nile fever, may cause some or all of the following symptoms:
- Abdominal pain
- Fever, headache, and sore throat
- Lack of appetite
- Muscle aches
- Nausea, vomiting, and diarrhea
- Rash
- Swollen lymph nodes
These symptoms usually last for 3 to 6 days, but may last a month.
More severe forms of disease are called West Nile encephalitis or West Nile meningitis, depending on what part of the body is affected. The following symptoms can occur, and need prompt attention:
- Confusion or change in ability to think clearly
- Loss of consciousness or coma
- Muscle weakness
- Stiff neck
- Weakness of one arm or leg
Exams and Tests
Signs of West Nile virus infection are similar to those of other viral infections. There may be no specific findings on a physical examination. About one half of people with West Nile virus infection may have a rash.
Tests to diagnose West Nile virus include:
- Blood test or a spinal tap to check for antibodies against the virus
- Head CT scan
- Head MRI scan
Because this illness is not caused by bacteria, antibiotics do not treat West Nile virus infection. Supportive care may help decrease the risk for developing complications in severe illness.
Outlook (Prognosis)
People with mild West Nile virus infection do well after treatment.
For those with severe infection, the outlook is more uncertain. West Nile encephalitis or meningitis may lead to brain damage and death. One in ten people with brain inflammation do not survive.
Possible Complications
Complications from mild West Nile virus infection are very rare.
Complications from severe West Nile virus infection include:
- Brain damage
- Permanent muscle weakness (sometimes similar to polio)
- Death
When to Contact a Medical Professional
Contact your health care provider if you have symptoms of West Nile virus infection, particularly if you may have had contact with mosquitoes. If you are very sick, go to an emergency room.
There is no treatment to avoid getting West Nile virus infection after a mosquito bite. People in good health generally do not develop a serious West Nile infection.
The best way to prevent West Nile virus infection is to avoid mosquito bites:
- Use mosquito-repellant products containing DEET (N,N-diethyl-meta-toluamide)
- Wear long sleeves and pants
- Drain pools of standing water, such as trash bins and plant saucers (mosquitos breed in stagnant water)
Community spraying for mosquitoes may also reduce mosquito breeding.
Alternative Names
Encephalitis - West Nile; Meningitis - West Nile
Centers for Disease Control and Prevention website. West Nile virus. www.cdc.gov/westnile/index.html. Updated December 15, 2022. Accessed January 9, 2023.
Naides SJ. Arboviruses causing fever and rash syndromes. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 358.
Thomas SJ, Endy TP, Rothman AL, Barrett AD. Flaviviruses (dengue, yellow fever, Japanese encephalitis, West Nile encephalitis, Usutu encephalitis, St. Louis encephalitis, tick-borne encephalitis, Kyasanur forest disease, Alkhurma hemorrhagic fever, Zika). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 153.
Review Date 12/4/2022
Updated by: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.


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Jeff Franzel
Jeff Franzel is a multi-talented songwriter and composer with over 30 years experience in the music business. Jeff began his career as a jazz pianist and toured with many groups, including big band legend Les Brown. During that time he accompanied such artists as Frank Sinatra, Sammy Davis Jr., and Mel Torme. Jeff has been a Yamaha artist for over a year now. He recently recorded a CD and DVD to a live audience in Montreal at the Oscar Peterson Hall on a Yamaha CFX Piano. Jeff is planning on releasing the CD and DVD in October, 2013.
Jeff has written pop songs for such diverse artists as Josh Groban, Placido Domingo, Push Play, Hayley Westenra, Clay Aiken, Shawn Colvin, N'sync, Dianne Reeves, Taylor Dayne, and Chuck Wicks. He writes in virtually all styles and works with lyricists in many languages. Jeff's songs have been featured on over 20 platinum albums in the U.S. and other countries. On the U.S. Billboard charts Jeff has had a #2 pop hit with Don't Rush Me, a top 10 AC hit with You've Got a Way and a #1 contemporary Christian song called Love Was Never Meant To Die. He has had top ten hits in Japan, England, Brazil, Australia, Holland, Belgium and Poland.
Jeff has a song that Placido Domingo and Josh Groban recorded with lyrics adapted by Pope John Paul II which was #1 on the classical billboard charts this summer. His song "When You Know" is the title track to Dianne Reeves CD. He recently had a platinum record in Italy with the San Remo winner Marco Carta on Warner Bros. Jeff co-wrote 3 songs with Hayley Westnera for her upcoming Christmas Winter Magic CD which will be released worldwide this November. This fall Jeff's songs were featured on two top 10 DVD's in Brazil by artist Ricky Vallens and Tania Mara. Kaci Battaglia recently recorded "Seeing You" which will be featured on her upcoming release on Warner Curb Records.
Jeff has also had a number if his songs in film and TV. He has had songs in Runaway Bride, Serendipity, Dawson's Creek, Deja Vu, Confessions of a Teenage Drama Queen, Barbershop 2, Go Figure, Dear God, Gray Matters and Fort McCoy.


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Clay writes – "When friend of QJ.NET "Crazy Jon" called us up and told us about a project he was working on, we didn't believe it at first. But when we got to his house, sure enough — twelve 30-inch Dell flatscreen monitors are sitting in his office, and he's grinning from ear to ear. Also among the pile of goodies are six NVidia GeForce 7900 GTX 512mb video cards, and three Turbo-Cool 1KW 1000-watt power supplies. Soon the QJ.NET crew was busy unboxing and tackling the project of mounting these bad boys." – Link.
Related note, 5 – 32″ Mac monitors too!?
Join Make: Community Today


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Under counter Complete set - Beer Dispenser, Beer Machine - AS-40, 2-line, flow cooler, wet cooler - dispensing column, Green Line
Item number NEW-3794
Manufacturer: ich-zapfe
* Incl. VAT excl. Shipping
Fast delivery We deliver fast. With DHL your package will be with you in a short time!
Top Quality Highest quality products from world leading manufacturers!
Happy Customers More than 90% of our customers are satisfied & recommend us to others.
Sicherheit Sicheres Online-Shopping mit SSL-Zertifikat.


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Posted by: Clear Advantage in Featured, Uncategorized on February 28, 2018
There are many reasons that people exercise – increased energy, weight loss, and several additional benefits. But have you ever heard how regular exercise can keep your eyes on their A game? Here is how regular exercise is helping your vision!
Living a sedentary lifestyle can put you at risk of developing conditions like cataracts, glaucoma, and age-related macular degeneration. By increasing the amount of exercise you are doing daily it will help increase your health and avoid falling victim to conditions such as diabetes and high blood pressure that can put your overall health and vision at risk.
Here are some tips on how to increase your physical activity throughout the week:
Give yourself a step goal:
Life gets busy and usually exercising becomes less of a priority then it should be. By giving yourself a realistic goal of how many steps you should take in a single day it can really help you get moving more and increase your activity level! Walking more throughout the day will have an impact on decreasing your chances developing age-related macular degeneration.
Give yourself rewards:
People are easy to become discouraged and give up on exercising completely. By setting goals that are followed up with rewards you can motivate yourself to stay on track and not fall behind!
By increasing the amount of activity in your life it will help you keep your blood pressure and cholesterol in check and decrease your chances of developing glaucoma, cataracts, or age-related macular degeneration!


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The Semiconductor Industry Association announces a newly finalized Department of Defense rule that reduces the risk of counterfeit semiconductor products being used by the U.S. military by implementing needed safeguards in the procurement of semiconductors and other electronic parts. The final DoD rule addresses contractor responsibilities for detection and avoidance of counterfeit electronic parts. Among other provisions, the rule implements section 818 of the National Defense Authorization Act (NDAA) for fiscal year 2012, which calls for DoD to utilize trusted suppliers to mitigate the risks of counterfeits.
"Counterfeit semiconductor products can end up in critical consumer, industrial, medical, and military devices, potentially undermining our public safety and national security," says Brian Toohey, president and CEO, Semiconductor Industry Association. "The new Department of Defense rule will help stem the tide of dangerous counterfeit semiconductor products by mandating that DoD contractors purchase from original manufacturers or authorized sources. This rule represents a long fought victory for the semiconductor industry and a significant step toward ensuring the safety and security of semiconductor products used by our military."
While the proposed rule issued last year contained numerous issues of concern for the semiconductor industry, the final rule incorporates many improvements called for by SIA in comments filed last year. The final rule requires contractors and their subcontractors to establish a counterfeit electronic part and avoidance system, subject to audit, that includes procedures to show their use of original manufacturers, authorized distributors, or authorized aftermarket distributors prior to turning to other outlets. Additionally, the rule further strengthens flowdown requirements to subcontractors called for by SIA and subjects violators of the requirements within the rule to disapproval of their purchasing system and/or potential withholding of payments by DoD.
SIA has long advocated for measures to stop the dangerous proliferation of counterfeit semiconductor products. Counterfeiters often "harvest" semiconductor components from old circuit boards and then re-mark them to indicate they are new or that they have better performance than the original components. These counterfeit semiconductors, which may be indistinguishable from authentic semiconductors, are then sold through a network of international brokers, posing a risk to critical end products.
"By working together to implement common sense policies like this DoD rule, we can win the fight against counterfeit semiconductor products and help ensure the safety of technologies that are vital to America's economic and national security," says Toohey.
Release Date: May 14, 2014
Source: Semiconductor Industry Association


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Welcome to the newcastlefootball.net foz - all users are welcome. We are pretty easy going - but there are obviously guidelines to ensure everyone enjoys themselves.
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Have you been arrested and charged with theft, drug offenses, or weapons offenses in Guttenberg, Hudson County New Jersey?
Being charged with a crime such as theft, drugs or weapons offenses is a life changing moment. What do you do? Who do you trust? How do you know that you will be more than just a file?
As someone who has seen the ebbs and flow of the criminal world, Attorney Chirag Mehta knows that every case is different and ever person has a story.
As an attorney who has practiced in more than 100 courts in the State of New Jersey you can be assured of receiving the personal touch and care needed to represent your case and present you with the best advice and guidance.
When you retain the Law Offices of Chirag D. Mehta, LLC you will be assured that you will get honest representation and not just a sales pitch. After all, getting charged with a crime in Jersey City is treated differently than getting charged with a crime in Hackettstown and you need an attorney that understands that.
Our law office handles all types of criminal charges including:
- Assault
- Domestic Violence
- Drug Offenses (Marijuana, cocaine, manufacturing and distribution, and synthetic marijuana)
- Theft offenses including shoplifting
- Weapons


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<transcy>E1 Optional roller for Bead Bender TB-12</transcy>
También puedes contactarnos por Email
Agrega tu correo y uno de nuestros agentes se pondrá en contacto contigo.
E1 Optional roller for Bead Bender TB-12
Item No. 173801-43
Summary of Return Policy.
1.Kaka Industrial will accept returns on any unopened product within 30 days of the original ship date. A 15% returns processing fee will be subtracted from the original cost and a credit for the difference will be issued. Shipping costs are not refundable.
2.3 Day acceptance period from date of delivery. Damage claims and order discrepancies will not be accepted after this time.
3. You must obtain a Kaka Industral issued RGA number PRIOR to returning any materials.
4.Returned materials must be received at Kaka Industrial in new condition and in original packaging.
5.Altered items are not eligible for return.
6.Buyer is responsible for all shipping charges.
7. A 15% re-stocking fee applies to all returns.


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Console Corner: Street Fighter in first person, gimmick or genius?
Ultra Street Fighter II: The Final Challengers, the Nintendo Switch version of Capcom's classic fighting game, will apparently feature a first-person mode that makes use of the console's Joy-Con controllers.
Yes you read that correctly, if you have a Switch you could be thorwing hadokens in just over a month or indeed the very prospect of it might make you want to get the console if you haven't already.
Hide AdAdvertisement
Hide AdVideo footage of the mode has appeared online, showing off how it is played.
The mode was shown during a Japanese Capcom TV stream and seems to be called "Way of the Hado."
Players hold a Joy-Con in each hand, then thrust their hands out to throw fireballs at enemies that appear on screen.
Using an uppercut motion it's possible to execute a Shoryuken and swiping both hands laterally executes a Tatsumaki Senpukyaku. The goal is to keep knocking out the enemies for as long as possible and build up a high score. Players are awarded points based on clear times and combos.
Hide AdAdvertisement
Hide AdAlthough Ultra Street Fighter II for Switch is a 2D sprite-based game, Way of the Hado is 3D and uses assets from Street Fighter IV.
Capcom released a version of Street Fighter IV for 3DS and included an over-the-shoulder perspective option.
From what I have seen I have very real doubts over the longevity and quality of a mode which - if done properly - could be superb.
There was a fair bit of lag in the footage I watched and I was bored watching it after a minute or so, let alone playing it.
Of course these things could be vastly improved before its May 30th release, but I'm very much in the 'rubbish gimmick' camp for now.


text: The Maddox's, all various spellings, family tree has many branches; we hope to be a resource that you reach out to as a key tool in your quest to uncover your roots. We also encourage you to checkout our DNA Maddox Etc. website to assist you in finding exact connections to current relatives searching for the same dead ends. Thanks to Katheryn Maddox Haddad for compiling the data on this website. Join Message Board - FreeThis world-wide Yahoo group is for those interested in connecting with others to "compare notes" on all Maddox spellings genealogy. More info » |


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Los Angeles' ANCESTORS create mighty, modern music that dovetails slow, heavy riffs and atmospheric, melodic instrumental passages, exuding a deep sense of melancholy.
Six years have passed since the band's previous album, In Dreams and Time, which came at a transitional and difficult time in each of the band members' lives. In those six years, the band has slimmed down from a 5-piece to a 3-piece, also adding drummer (Daniel Pouliot of HORSE THE BAND and ex- SILVER SNAKES) to their ranks. This lineup has consciously taken their time in writing their 5th album. It was surely worth the wait: "Suspended in Reflections" is a culmination of everything the band have accomplished thus far. It feels like ANCESTORS have finally arrived at their own, right place.
"I think that as songwriters we've grown exponentially over the past six years", comments guitarist and vocalist Justin Maranga… "but the most important change was the removal of ego from the writing and recording process. We tried to step out from behind our respective instruments to write the best album we could. We made a beautiful record as a team."
ANCESTORS' soundscapes are slow and vast, melancholic, dreamy and heavy, all at the same time: fertile soil for venturing outside of the typical realms of rock and metal instrumentation. The jazzy bass lines in "Release" and the proggy strings in "Into The Fall" prove that the 3-piece is not confined to any specifc genre of music. The use of an Aeolian-Skinner church organ, however – an instrument with close to 1.941 pipes – woven throughout the album, is the proof that these
excursions are not blind experiments, but landmarks of a sonic path that this band has carefully chosen.
In their 11 years as a band, ANCESTORS has toured multiple times and played festivals in Europe, the US and Canada.


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Regional Organizations Serving Boone County, Indiana |
The following regional organizations provide service to the Boone County community. If your organization would like to be listed on this page (it's free!) contact .
Alzheimer's Association - Greater Indiana Chapter
50 E. 91st Street, Suite 100
Indianapolis, IN 46240
American Red Cross of Greater Indianapolis
441 East Tenth Street
Indianapolis, IN 46202-3388
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To remember the great man at his very best, here's a feature from 2008 in which we asked our expert writers and contributors for their ultimate Hendrix moment, giving you Hendrix's 11 greatest ever tracks.
Did we get it right? What did we miss? Post your comments below, but in the meantime, make the ultimate Jimi playlist for your iPod by dragging and dropping these 11 killer cuts...
Bold As Love
The beautiful closing title track on Axis: Bold As Love sees Jimi paint a lyrical rainbow across his most effortlessly pretty rhythm guitar performance. A loose groove blasts off into a psychedelic sunset after the second chorus at 1:50, before a false ending gives way to a key change and a heavily phased coda. Little Wing is often cited as the best example of Jimi in mellow mode; this is better.
Fact! Hendrix referred to George Chkiantz and Eddie Kramer's stereo phasing technique as the sound he had been "hearing in his dreams".
by Chris Vinnicombe, MusicRadar
The Wind Cries Mary
The Experience's third single was written after a spat with his then-girlfriend Kathy (Mary) Etchingham about her cooking: fitting then, that this make-up song is so tasteful, containing all the ingredients that elevated Hendrix so far above his psychedelic peers.
And it's all about that solo. The most beautiful playing in his entire discography, it blends doublestops, rhythm and lead, major and minor harmony and spacious, lyrical phrasing with breathtaking dynamic range… the way he targets the chords alone shows what a master Hendrix was.
Fact! "We were recording the B-side of Purple Haze and there was 20 minutes left in the studio," recalled Chas Chandler. "It was recorded, including five guitar overdubs, in the 20 minutes." What a genius.
Watch! Jimi live in Stockholm, in 1967.
by Owen Bailey, Guitarist magazine
Spanish Castle Magic
Jimi's often thought of as this wild showman, pranging his vibrato bar and setting fire to his Strat. People don't often talk about the great riffs he wrote. For me, Spanish Castle Magic is one of them. I love the way it combines single string riffing with that nasty sounding C#m7 using the top two open strings. It's a subtle thing, but these subtleties are often what make the great players stand out from the rest.
Watch! Spanish Castle Magic at Woodstock
by Stephen Lawson, Total Guitar magazine
Wait Until Tomorrow
This is Jimi showing the world once again that a mental guitar part and a complicated vocal aren't mutually exclusive. Jimi gets mucked around by the indecisive Dolly Mae, then unceremoniously shot by her protective father. Bummer, dude. One 'expert' dismissed it as a "disposable… comedy number", accusing the Experience of indulgence. What tosh! Humourlessness is a critical cul-de-sac, but Jimi's sense of fun will be forever boundless.
Watch! An impressive cover by John Mayer.
by Mick Taylor, Guitarist magazine
Crosstown Traffic
Sounding like a sleazy sequel to The Beatles' Drive My Car, Crosstown Traffic grooves harder than it rocks and is all the better for it. Underpinned by a pounding piano part - which Jimi played himself - it provides evidence of Hendrix's considerable hook-writing prowess and features the finest use of the kazoo in the history of popular music. That's more than enough for me.
Fact! Crosstown Traffic features Dave Mason from British band Traffic on backing vocals. And of course, he sings the word 'traffic'.
Watch! If you want, Red Hot Chili Peppers covering it.
by Ben Rogerson, MusicRadar
Hear My Train A Comin'
The live version of this epic blues from the Rainbow Bridge album has the lot. Yes, at the start it's out of tune but Jimi soon bends things into shape, and what follows in the ensuing 11 minutes represents some of the best blues guitar ever committed to record. Immense Strat tone, total control and utter creativity make this my top Hendrix tune. He was a master - make no mistake about it.
Watch! Jimi live at Berkeley.
by Neville Marten, Guitar Techniques magazine
All Along The Watchtower
Ok, it's a cover. But not many covers better (piss all over) the original version as convincingly as All Along The Watchtower - and Bob Dylan was the first to agree. Sure, Watchtower began life as a folk number, but turning that warbling harmonica into the world's coolest riff was a defining moment of Jimi's genius. It's also the perfect soundtrack to the self-destructive life we never lived. If you've seen Withnail And I, you'll know what I mean.
Fact! The band's bassist Noel Redding walked out halfway through Watchtower's recording session in 1968. Guitarist Dave Mason took over, but Hendrix himself recorded the final part.
Watch! Live at the Isle Of Wight 1970 "If you can dig it?"
by Tom Porter, MusicRadar
Little Wing tends to be the 'go to' song when the words 'Hendrix' and 'tasty chords' are strung together. Shame, as there are more corking fretboard moves and evocative chord voicings in Angel than any version available of Little Wing (and that includes covers by players like Stevie Ray Vaughan or Guthrie Govan). Certainly, few E chords (Eb chords if we are to consider the semi tone down tuning) are as sonic velvet as the opening Emaj9…
Fact! Angel has only notched up one notable cover version and that's by Rod Stewart And The Faces. Sadly, the nice chord voicings went out of the window.
by Jason Sidwell, Guitar Techniques magazine
Manic Depression
While there is no evidence that Jimi Hendrix actually suffered from bipolar disorder, he certainly nailed an appropriate zig-zagging mood on this explosive, waltz-time(!) cut. As much as Hendrix dominates the song, with his usual scorching soloing and an exaggerated singing style that sometimes spills over the meter, drummer Mitch Mitchell's somersault-like approach to the 3/4-time arrangement is a breathtaking mini-course in jazz, rock and blues.
Fact! Manager Chas Chandler told Hendrix that he sounded 'manic depressive' at a press conference. The next day, Jimi wrote this song.
by Joe Bosso, MusicRadar
Voodoo Child (Slight Return)
An intense blues heavily-influenced by Muddy Waters' Rollin Stone, Electric Ladyland's closing track is one of Hendrix most self-mythologizing epics. Here he chops down a mountain "with the edge of my hand" and promises to meet us in the next world ("don't be late!") - prescient, given its place on his final fully-realised album. It's the band performance that makes it: a sound that's near exploding in its own frenzy and a song that you should never, ever attempt to cover.
Fact! It's Joe Satriani's favourite Jimi track: "It's just the greatest piece of electric guitar work ever recorded. In fact, the whole song could be considered the holy grail of guitar expression and technique. It is a beacon of humanity."
Watch! Live on BBC TV January 1969, Saturday night prime time.
by Michael Leonard, MusicRadar
Red House
Songwriting genius aside, it's Hendrix's guitar playing that made him famous. If, then, you're in the mood for some untethered and raw blues soloing, 12-bar Red House is the perfect musical plate from which to enjoy Jimi's skills. The piece is such a classic that it's become a blues standard, having been covered by Buddy Guy, Gary Moore, John Lee Hooker, Albert King and more.
Fact! Red House didn't make it onto the US release of Are You Experienced. Why? According to Jimi, the label claimed "America doesn't like blues". Quite. And guitar groups are on their way out, Mr Epstein
by Chris Wickett, MusicRadar


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- Up until about an hour ago, most Americans thought Benghazi was the guy who palled around with John Cassavetes back in the 60s, but now it's obvious we're talking about the foreign policy arm of a multi- ramped tar pit the President has found himself swimming-up to his armpits. Yes, friends, it's pity time at the White House.
- After flogging the issue nonstop since September 11, the Fox News Team's persistence finally pushed the story of the Libyan Embassy riot that resulted in the death of 4 Americans over the cliff into the public consciousness. Space available only because both Honey Boo Boo and Duck Dynasty are on hiatus.
…even more penetrating questions such as: "Who cares? What difference does it make? Aren't we stuffed to the gills with enough partisan gobbledy goop already?"
- The hue and cry from the right is demanding many questions be answered. Was the protest planned or spontaneous? Did the group that initiated the attack have any affiliation with Arab terrorists? Who altered the talking points; the CIA or the State Department? Where were the drones? Queens? Wasps? Chigger mites? How many angels can dance on the head of a bent and broken Romney/ Ryan pin? What would Cheney do?
- Having taken all this in, the American people responded with what can only be characterized as even more penetrating questions such as: "Who cares? What difference does it make? Aren't we stuffed to the gills with enough partisan gobbledy goop already? Does anyone really give an albino rat's ass? Isn't there a seafood buffet around here somewhere?"
- The revelations have been as startling as mint jelly on lamb. Tragic violent events occurring in the Middle East? Oh no! Not that. Perpetual infighting amongst government agencies? That couldn't happen here, could it? Republicans accusing a Democratic administration of not being patriotic enough? What are the odds?
- Next you'll tell me the Justice Department investigation of the Justice Department's seizure of AP reporters' phone records will lead to the Justice Department concluding that the Justice Department did nothing wrong. The public's eyes are glazing over like a 5th grader lectured on the nutritional aspects of broccoli rabe.
- Haven't we been told for the last twenty, thirty years that Libya is a godless pit of iniquity and now they want us to heap truckloads of blame onto our own guys because someone got killed over there? After they themselves voted down additional money for embassy security? Another example of that whole "dynamite the front steps then complain what a pain it is to climb into the house on a rope ladder" school of logic.
- But the GOP remains convinced they have the administration on the run, and is calling for all sorts of investigative committees and dedicated inquiry boards and pretty soon it will be special prosecutors and court rooms full of hopping kangaroos and then pointy sticks and barbed wire and dungeon doors with keys specifically designed to be thrown away. Just in time for the midterms.
- And if everything goes according to plan, Hillary Clinton and her nascent 2016 Presidential run will wither and rot behind the same Benghazi charges. But the Republicans must know how tricky this sort of maneuver can be. As with all smoke screens, you have to pay real close attention to which way the wind blows, or you could easily end up choking on the same stuff you're spreading.
- Recipient of 7 consecutive nominations for Stand Up of the Year, Will Durst's new one- man show "BoomerAging: From LSD to OMG" is presented every Tuesday, at the Marsh, San Francisco. Go to… themarsh.org or willdurst.com for more info.


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Starting a new project and want to make sure you're getting the best system for your money? Looking to retrofit an existing greenhouse or grow room? We've got you covered every step of the way from design and engineering to construction and installation.
Existing customers can use this form for any support requests or questions.
Business Hours: M-F 7:00 AM – 5:00 PM
Saturday 7:00 AM – 12:00 PM
Phone: (831) 235-4100


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Mission To provide our members with information, that will assist them in bidding construction projects in the Lincoln and surrounding areas.
History The Lincoln Builders Bureau was founded in 1932, by General Contractors, Architects and Engineers who wanted a local plan room to house blueprints for sub contractors and suppliers. It became "membership owned". The purpose was to alleviate traffic in their offices. The Lincoln Builders Bureau's first office was in the Chamber of Commerce downtown. In 1968 the Builders Bureau purchased its own office at 507 "J" St., with a total of 192 paying members. November 30, 1990 marked the date for the move from 507 "J" St. to the Lincoln Trade Center, 5910 S. 58th St, Suite C.


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Custom Single Letter Borderless Botanical Wax Seal Stamp - Style 14
Head Size
Handle Finish
Upgrade to Kit
Elevate your personal touch with our Custom Single Letter Borderless Botanical Wax Seal Stamp. This exquisite design allows you can combine your own initial with a delicate botanical border. Each stamp is meticulously crafted to add a touch of elegance and sophistication to your correspondence, invitations, gifts, and more. With its seamless connection between the initial and the border, this wax seal stamp exudes timeless beauty and creates a lasting impression.
Embrace the art of customization with this wax seal stamp collection. Choose your preferred initial from A to Z and select the botanical border design that resonates with your personal style. Whether you opt for a delicate leaf motif, a floral arrangement, or a combination of nature-inspired elements, each design captures the essence of natural beauty.
To enhance your wax sealing experience, we recommend pairing these wax seal stamps with our high-quality wax beads, wax sticks, melting equipment, and highlighting ink pads. Achieve flawless results and create captivating impressions with ease. Whether you prefer a classic and traditional aesthetic or a modern and stylish look, our Celebrate Wedding Wax Seal Stamp collection provides the perfect finishing touch to your wedding stationery ensemble.
◎4 HEAD SIZES: 25mm (1"), 30mm (1.18"), 35mm (1.38") and 40mm (1.57") in diameter. 25mm and 30mm are more commonly used; 35mm and 40mm for high detail arts;
◎10 HANDLE STYLES: fancy, walnut, black, silver tone, gold tone, rose gold tone, bronze tone, copper tone, rose quartz, and white quartz (35mm and 40mm stamps are only available in gold, black, fancy, walnut, and quartz handles. If you choose other colors, we will replace it with the gold handle);
◎UPGRADE TO KIT: You can choose to upgrade your wax seal stamp to Premium Kit (+1 melting spoon & mixed color wax beads). Get everything you need for a perfect wax seal in one click and save up to 25%! Details of the kits can be found in pictures 9 and 10.
◎Didn't find the desired wax seal? We can also make Fully Customized Wax Seal Stamps with your artwork.
◎For instructions on creating the perfect wedding wax seal, please visit here.
A: Production takes 2-3 business days, and shipping times vary: 4-7 business days for VIP express and 10-14 business days for standard shipping. Please note that delivery times may be subject to change due to customs procedures.
Q: Can I make some modifications to this wax seal stamp design?
A: Absolutely! You can make modifications to our designs, such as changing signs, removing small symbols, or adding custom text. Simply contact our customer service team and provide your additional requirements. If you require extensive modifications, we recommend ordering a fully customized wax seal stamp, which can be found at https://amzdeco.com/products/fully-customized-wax-seal-stamp-with-your-own-artwork.
Q: Can I preview my custom wax seal stamp before production?
A: Generally, we do not provide a preview of semi-customized wax seal stamps before production. However, if you require a preview, we can send you one after you place the order.
Q: How much wax is required for different seal sizes?
A: The amount of wax needed depends on the seal size. As a general guideline, a 25mm seal requires approximately 3 wax beads, a 30mm seal requires 4 beads, a 35mm seal requires 6 beads, and a 40mm seal requires 7 beads. One wax stick can produce around 10 seals of 25mm (1"), 7.5 seals of 30mm (1.18"), 6 seals of 35mm (1.38"), or 5 seals of 40mm (1.57").
Q: Can I purchase only wax seal stamp heads?
A: Yes, if you are ordering multiple wax seal stamps, at least one stamp must include a complete "stamp head + handle" set. The remaining stamps can be ordered as heads only. Simply place your order and provide us with your order number, and we'll update the order and refund the cost of the extra handle(s).
We ship internationally to every corner of the world, whether you are in North America, Europe, Oceania, South America, Asia or the Middle East.
We provide 3 shipping methods from standard to expedited shipping. Free shipping is offered on orders over a certain amount.
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Stamprints offers returns and exchanges. Please refer to our Returns Policy Page.


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Last updated: November 14, 2012
Researchers Identify Gene for Premature Aging Disorder
Researchers Identify Gene for Premature Aging Disorder
Progeria Gene Discovery May Help Solve Mysteries of Normal Aging
WASHINGTON, D.C., April 16, 2003 - A team led by the National Human Genome Research Institute today announced the discovery of the genetic basis of a disorder that causes the most dramatic form of premature aging, a finding that promises to shed new light on the rare disease, as well as on normal human aging.
In their study, to be released online next week in the journal Nature, researchers identified the genetic mutations responsible for Hutchinson-Gilford progeria syndrome (HGPS), commonly referred to as progeria. Derived from the Greek word for old age, "geras," progeria is estimated to affect one in 8 million newborns worldwide. There currently are no diagnostic tests or treatments for the progressive, fatal disorder.
Francis S. Collins, M.D., Ph.D., director of the National Human Genome Research Institute (NHGRI) and leader of the research team, said, "This genetic discovery represents the first piece in solving the tragic puzzle of progeria. Without such information, we in the medical community were at loss about where to focus our efforts to help these children and their families. Now, we finally know where to begin."
Dr. Collins added, "The implications of our work may extend far beyond progeria to each and every human being. What we learn about the molecular basis of this model of premature aging may provide us with a better understanding of what occurs in the body as we all grow older."
In addition to NHGRI, the multi-institution research team included scientists from the Progeria Research Foundation; the New York State Institute for Basic Research in Developmental Disabilities in Staten Island, N.Y.; the University of Michigan in Ann Arbor; and Brown University in Providence, R.I.
W. Ted Brown, M.D., Ph.D., co-author of the study and chairman of the Department of Human Genetics at the Institute for Basic Research, said, "Many people consider progeria to be the most dramatic example of a genetic disease that clearly resembles accelerated aging. The children appear to have an aging rate that is 5 to 10 times what is normal." Dr. Brown is widely regarded as the world's leading clinical expert on progeria.
Children with progeria usually appear normal at birth. However, within a year, their growth rate slows and their appearance begins to change. Affected children typically become bald with aged-looking skin and pinched noses. They often suffer from symptoms typically seen in elderly people, especially severe cardiovascular disease. Death occurs on average at age 13, usually from heart attack or stroke.
Leslie Gordon, M.D., Ph.D., medical director of the Progeria Research Foundation (PRF) and executive director of the PRF Genetics Consortium, said, "Isolating this gene is just the beginning. It is our goal to find treatments and possibly a cure for this rare, life-threatening disease that robs children of their adulthood. The Progeria Research Foundation will continue to lead the fight against progeria."
In 2001, PRF co-hosted a workshop with various institutes and centers of the National Institutes of Health (NIH), including the National Institute on Aging and the Office of Rare Diseases. The workshop brought together leading scientists from around the world to identify promising areas of research in progeria. This partnership eventually led to funding for progeria research and the formation of the PRF Genetics Consortium, a group of 20 scientists whose common goal is to find the genetic cause of progeria and to develop ways of treating the disease. Six of those scientists are co-authors of the study to be published in Nature.
Dr. Collins commended the collaborative efforts, saying, "The Progeria Research Foundation's commitment and cooperation played a key role in the hunt for the disease gene. They brought the urgent need to find this gene to the attention of the biomedical research community."
Earlier this week, Dr. Collins, as leader of the Human Genome Project, announced the successful completion of the international project's effort to sequence the 3 billion letters that make up the human genetic instruction book. "Free and unrestricted access to the human genome sequence is greatly speeding the pace of disease gene discovery. Finding the gene for progeria would have been impossible without the tools provided by the Human Genome Project," said Dr. Collins, who still spends some of his time in a small research lab at the National Institutes of Health (NIH). "This was a particularly challenging project for the gene hunters, since there are no families in whom the disease has recurred, and geneticists generally depend on such families to track the responsible gene. This was a detective story with very few clues."
Taking advantage of an array of genomic technologies - from whole-genome scans to high-throughput sequencing of targeted DNA regions - researchers determined the most common cause of progeria is a single-letter "misspelling" in a gene on chromosome 1 that codes for lamin A, a protein that is a key component of the membrane surrounding the cell's nucleus. Specifically, the researchers found that 18 out of 20 children with classic progeria harbored exactly the same misspelling in the lamin A (LMNA) gene, a substitution of just a single DNA base - a change from cytosine (C) to thymine (T) - among the gene's 25,000 base pairs. In addition, one of the remaining progeria patients had a different single base substitution - guanine (G) to adenine (A) - just two bases upstream. In every instance, the parents were found to be normal indicating that the misspelling was a new, or "de novo," mutation in the child.
At first glance, the point substitution in the LMNA gene would appear to have no effect on the production of lamin A protein. "Initially, we could hardly believe that such a small substitution was the culprit. How could these bland-looking mutations lead to such terrible consequences in the body?" said NHGRI's Maria Eriksson, Ph.D., a post-doctoral fellow in Dr. Collins' lab and the first author of the study.
However, when Dr. Eriksson conducted laboratory tests on cells from progeria patients, she found that the minute change in the LMNA gene's DNA sequence dramatically changed the way in which the sequence was spliced by the cell's protein-making machinery. The end result was the production of an abnormal lamin A protein that is missing a stretch of 50 amino acids near one of its ends.
To determine what effect abnormal lamin A has upon cells, the NHGRI-led team used fluorescent antibodies to track lamin A in skin cells taken from progeria patients known to have the common misspelling, as well as skin cells taken from unaffected people. The studies showed that about half of the cells from the progeria patients had misshapen nuclear membranes, compared with less than 1 percent of the cells from the unaffected controls.
"We suspect that this instability of the nuclear membrane may pose major problems for tissues subjected to intense physical stress - tissues such as those found in the cardiovascular and musculoskeletal systems, which are so severely affected in progeria," said Dr. Eriksson, noting that nuclear instability ultimately may lead to widespread death of cells.
Researchers hope to move their new findings into the clinic almost immediately with the development of a genetic test for progeria. Such a test will help doctors diagnose or rule out progeria in young children much earlier than their current method of looking at outward physical changes.
The new findings also may have implications for the treatment of progeria, with the newfound understanding of progeria's molecular roots pointing to possible therapeutic approaches. For example, researchers plan to explore the possibility that statins and/or other drugs known to inhibit a step in protein processing, known as farnesylation, might reduce the production of abnormal lamin A in progeria patients. Another avenue for identifying possible therapies involves screening large libraries of chemical molecules with the hope of finding a compound that can reverse the nuclear membrane irregularities seen in the cells of progeria patients.
"It is impossible to predict how soon our findings will translate into treatments for children suffering from progeria. We and other researchers across the nation will be working hard to find ways of helping them. Unfortunately, as we have witnessed with other genetic discoveries, the road from the lab to the clinic is not always swift or smooth," Dr. Collins said.
More also remains to be done to determine what role the LMNA gene may play in the normal aging process. "Aging clearly has a strong genetic component. Discovery of this key genetic mutation that causes progeria may lead to a much clearer understanding of what causes aging in us all. Eventually, this information may lead to improvements in health care for our aging population," said Dr. Brown.
Researchers plan to look at the LMNA genes of people who are exceptionally long-lived to see if there are any variants of the gene associated with longevity. Other studies might focus on determining whether repeated damage to the LMNA gene over the course of a lifetime may influence the rates at which people age.
"Our hypothesis is that LMNA may help us solve some of the great mysteries of aging," Dr. Collins said. "However, it will probably take more than one genetic key to unlock the secrets to a biological process as complex as aging. There are probably a host of other genes related to aging still waiting to be discovered."
Another interesting footnote to the recent findings is that different mutations in other regions of the LMNA gene previously have been shown to be responsible for a half-dozen other rare, genetic disorders. Those disorders are: Emery-Dreifuss muscular dystrophy type 2; limb girdle muscular dystrophy type 1B; Charcot-Marie-Tooth disorder type 2B1; the Dunnigan type of familial partial lipodystrophy; mandibuloacral dysplasia; and a familial form of dilated cardiomyopathy.
Prior to coming to NIH to lead the Human Genome Project in 1993, Dr. Collins had established a reputation as a relentless gene hunter using an approach that he named "positional cloning." In contrast to previous methods for finding genes, positional cloning enabled scientists to identify disease genes without knowing in advance what the functional abnormality underlying the disease might be. Dr. Collins' lab, together with collaborators, applied the new approach in 1989 in their successful quest for the long-sought gene responsible for cystic fibrosis. Other major discoveries soon followed, including identification of the genes for neurofibromatosis; Huntington's disease; multiple endocrine neoplasia type 1; one type of adult acute leukemia; and Alagille syndrome.
NHGRI is one of the 27 institutes and centers at the NIH, which is an agency of the Department of Health and Human Services. The NHGRI Division of Intramural Research develops and implements technology to understand, diagnose and treat genomic and genetic diseases. Additional information about NHGRI can be found at its Web site: www.genome.gov.
Geoff Spencer
(301) 402-0911


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Think about all the times you use the word "sorry" in a typical day. There are the necessary "sorry"s — when you bump into someone, when you need to cancel plans with a friend. But what about the unnecessary "sorry"s? The "sorry, this may be an obvious idea" at a meeting, the "sorry to cause trouble" when rescheduling a haircut, the "sorry, there's a spill in the dairy aisle" at the supermarket.
Canadian sociologist Maja Jovanovic believes the "sorry"s we sprinkle through our days hurt us. They make us appear smaller and more timid than we really are, and they can undercut our confidence.
Jovanovic, who teaches at McMaster University and Mohawk College in Hamilton, Ontario, became interested in this topic when she attended a conference four years ago. The four women on a panel were, she says, "experts in their chosen fields. Among them, they had published hundreds of academic articles, dozens of books. All they had to do was introduce themselves. The first woman takes a microphone and she goes, 'I don't know what I could possibly add to this discussion' … The second woman takes the microphone and says, 'Oh my gosh, I thought they sent the email to the wrong person. I'm just so humbled to be here.'" The third and fourth women did the same thing.
During the 25 panels at that week-long conference, recalls Jovanovic, "not once did I hear a man take that microphone and discount his accomplishments or minimize his experience. Yet every single time a woman took a microphone, an apologetic tone was sure to follow." She adds, "I found it enraging; I also found it heartbreaking."
Jovanovic found the outside world not so different: "Apologies have become our habitual way of communicating," she says. Since then, she's collected needless apologies from her colleagues and students. One stand-out? "My research assistant said 'Sorry' to the pizza delivery guy for his being late to her house," says Jovanovic. "She said, 'Oh my gosh, we live in a new subdevelopment. I'm so sorry. Did you have trouble finding this place?'"
We can eliminate the "sorry"s from our sentences — and still be considerate. "The next time you bump into someone," Jovanovic says, "you could say, 'Go ahead,' 'After you' or 'Pardon me.'" Similarly, during a meeting, Jovanovic says, "instead of saying, 'Sorry to interrupt you,' why not try 'How about,' 'I have an idea,' 'I'd like to add' or 'Why don't we try this?'" The idea is to be polite while not minimizing yourself.
The "sorry"s that fill our written interactions also need to be noticed — and banished. For emails, Jovanovic says, "There's a Google Chrome plug-in called 'just not sorry' that will alert you to all the needless apologies." With texts, she points out, "Every single one of us has responded to a text you got when you weren't able to respond right away. What did you say? 'Sorry.'" She says, "Don't apologize — say, 'I was working,' 'I was reading,' 'I was driving, 'I was trying to put on Spanx.' Whatever it is, it's all good. You don't have to apologize."
And, in some of the instances when we'd typically throw in a "sorry," we could just use the two magic words: "thank you."
Jovanovic tells of the moment when she realized the effectiveness of gratitude. She says, "Four of us were at a restaurant for a work meeting, and we're waiting for number five to arrive … I put my sociological cap on, and I thought, 'What would he say? How many apologies will he give?' I could barely stand the anticipation. He arrives at the restaurant, and you know what he says? 'Hey, thanks for waiting.' … The rest of us said, "Yeah, you're welcome," and we all just opened our menus and ordered. Life went on, and everything was fine."
Another time when "thank you" can work better than "sorry"? When you're with a friend and you realize you've been doing all the talking. Jovanovic says, "instead of saying, 'Sorry for complaining' or 'Sorry for venting,' you could just say, 'Thank you for listening,' 'Thank you for being there' or 'Thank you for being my friend.'"
Besides removing them from our own communications, we should tell other people when they're overdoing their "sorry"s, suggests Jovanovic.You can start with your family and friends — and if you'd like, go beyond them. She says, "I have been interrupting these apologies for three years now. I'll do it everywhere. I'll do it in the parking lot, I'll do it to total strangers at the grocery store, in line somewhere. One hundred percent of the time when I interrupt another woman and I say, 'Why did you just say 'sorry' for that?' she'll say to me, 'I don't know.'"
Watch her TEDxTrinityBellwoodsWomen talk here:
Daniella Balarezo is a Media Fellow at TEDx. She is also a writer and comedian based in NYC.
This post was originally published on TED Ideas. It's part of the "How to Be a Better Human" series, each of which contains a piece of helpful advice from someone in the TED community; browse through all the posts here.


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I'm a week into recovery and all I want is to be able to sleep laying on my stomach. Not for another 3 weeks… (okay, that's not *all* I want, but it's a start… also stretching my arms above my head, oh do I miss that, too!)
Most of the days since surgery have been pretty easy, with a couple exceptions for cranky moments and hard things. I'm super grateful to everyone who brought or bought me foods, especially in the first few days. Having food show up without me having to think much about it was so great and really really useful. And the folks who came over to care for me have been absolutely the best. Your company made the days go faster. You have helped me feel loved and cared for and knowing I could ask for something if I needed it has been so helpful. I still have a few more meals and a few more folks signed up, and I'm super grateful to you, too, and everyone who has read my posts in here and commented support. Lots of gratitude.
Wednesday, Stian helped me shower (yay! Finally!) and we removed the pad and bandage around my chest for likely the last time. I was told at the post-op appointment that I could remove the bandage once it stopped draining, and the bandage we removed yesterday was basically clean. I had previously only really had two chances to see my new chest, when changing the bandage. The last day and a half or so has been a strange and new version of surgery recovery, and also the most emotional so far.
With the bandage off, the physical reality of surgery has hit me. I've read about post-surgery depression, which happens with all types of surgery not just trans ones, and so I expected some of that given that my brain is used to depressed places. Expecting it and experiencing it, of course, are different. I've had all the emotions around surgery and I'm sure I'm not done. All the pre-surgery questions have come back, not surprisingly. I'm trying really hard to keep my ever-critical Virgo-rising eye from now obsessing over how my new chest looks because I know how it is now is not how it will be. I'm barely a week into healing and I haven't even seen the areola shape yet as I still have the steri strips on the incisions. Still, though, my brain is a fun overly critical anxious and depressed place, so I've been going all the worst places.
At the urging of one of my main care team folks, I read a few different narratives of post top surgery depression that I could find yesterday, and my care person today is someone who has had top surgery, so I'm planning on chatting with him about it. It has been useful to remind myself this is normal, that it is okay, that I won't feel this way forever, but it is still challenging. I hoped that all the doubt and uncertainty would go away with surgery and that I would love looking down at my new chest and feel so satisfied and content with it. Even though I also knew that wasn't going to happen right away and that there would be a period of adjustment and likely depression, part of me still hoped I could bypass that somehow. I hoped everything would click into place the way I felt after my first shot of T. Though, I must have forgotten my slow process with that, as well, and the months long break I took about six months in and the struggle and uncertainty there because of how right it feels now.
I am not binary, and that also makes all medical transition more complicated (I think… which is also not to say it isn't complicated for binary trans folks as well). My genderqueerness means there is no ideal chest, exactly, except for the one I choose. It does not need to look like a "man's chest" (though, also, there are billions of right ways for a chest to be a man's chest and tons of variation there, so wtf does that mean, anyway? But also, you know what I mean) nor a "woman's chest," (see previous parenthetical statement) and indeed it is neither of those things. It's mine. It is a genderqueer chest by nature of being on the genderqueer body of a genderqueer person.
The physical reality is still hitting me, and it will likely keep coming. I must build a new relationship with my new chest. I can't assume the old ways we were together still hold. We have to find new ways of being together, as in the aftermath of any traumatic experience (which surgery certainly, literally, is). And some of that process will be grieving. And some of that process will be gender euphoria. And some of that process will be pleasurable. And some of the process will be terrible. All of the process will be slow.


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Pelu Pelu
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- v50 information can now be added to pages in the main namespace. v0.47 information can still be found in the DF2014 namespace. See here for more details on the new versioning policy.
- Use this page to report any issues related to the migration.
This article is about an older version of DF. |
A biome is a biotic area with homogeneous features, characterized by distinctive plants, animal species and climate. A biome will also contain only one set of stone layers, though these usually expand beyond a single biome. Your dwarves will find different resources depending on which biomes you select when starting a fort.
Selecting a biome[edit]
Biomes are important when choosing a fortress location in order to understand your surroundings. Individual biomes, which form at least one map-tile of your embark location, can be cycled with the F#-keys; for example, an area with 3 biomes present can be cycled using F1, F2 and F3. The selected biome will be highlighted with flashing Xs on the Local Map, and the biome's information will be displayed on the right side of the screen.
Characteristics of biomes[edit]
Selecting different biomes gives you some ability to influence the difficulty of your game. Each biome has a different set of resources; the availability of trees, sand, certain plants or animals, and sometimes water is specific to a particular biome, and different biomes may have different stone layers containing flux, coal or useful ores. Mountains have a lot of ore, but no soil.
Generally it is advantageous to plot your embark location at the convergence of multiple different biomes, the more the better (within reason) - which is made easier if you enlarge your starting embarkation area. However, it is not usually too hard to find three or four biomes using the default size.
Note: Making the starting plot larger will slow your game down considerably; likewise, a small embark area can dramatically increase framerate. One embark square translates to 48x48 ingame tiles
By making use of several biomes you can provide more resources for your fort. Making sure one of your biomes contains either a broadleaf or conifer forest will provide you with an ample supply of trees, even if the rest of your plot extends into badlands and desert.
All biomes also have some kind of "alignment" -- good, neutral, or evil -- and a degree of "savagery", which essentially measures how relatively peaceful the biome is. The combination of alignment and savagery is referred to as the biome's surroundings. However, a named region (which is a contiguous area of one category of biomes, such as forests or wetlands) will be either good, neutral, or evil. It is not uncommon to see a large mountain range with one alignment and a few mountains, disconnected from the main mountain range by a single region tile, with a different alignment. Therefore, the more biomes you have, the more likely it is to have combinations of different alignments and savageries, if so desired.
If your plot contains only ocean, lake or mountain biomes you will not be able to embark. The dwarves would have difficulty parking their wagon on water, while mountains are too barren and remote to reach.
Available Biomes[edit]
Wetlands may be Swamp or Marsh; may be Freshwater or Saltwater; and may be Temperate or Tropical. In addition, there are Mangrove Swamps.
- Taiga
- Temperate Coniferous Forest
- Temperate Broadleaf Forest
- Tropical Coniferous Forest
- Tropical Dry Broadleaf Forest
- Tropical Moist Broadleaf Forest
Plains include Grassland, Savanna and Shrubland; they may be either Temperate or Tropical.
- Tropical Ocean
- Temperate Ocean
- Arctic Ocean
Murky Pools[edit]
These include Freshwater, Saltwater and Brackish Pools, which may be either Temperate or Tropical.
Like pools, these may be Freshwater, Saltwater or Brackish Lakes, and may be either Temperate or Tropical.
Like pools and lakes, these may be Freshwater, Saltwater or Brackish Rivers, and may be either Temperate or Tropical.
- Subterranean Water
- Subterranean Chasm
- Subterranean Magma
Certain creatures and plants use special biome tokens to encompass several similar environments.
- "Not Freezing" includes all land biomes except Mountains, Glaciers, and Tundras. All plants require a "Not Freezing" biome (or a more specific biome group); you will be unable to grow any aboveground crops at all in a Mountain biome.
- "Any Temperate Broadleaf" includes temperate broadleaf forests as well as grasslands, savannas, shrublands, swamps, and marshes.
- "Any Tropical Broadleaf" includes tropical dry/moist broadleaf forests as well as grasslands, savannas, shrublands, swamps (including Mangrove), and marshes.
More information can be found in the Biome token list.
Generating a Biome[edit]
When using advanced world generation to attempt to create the "perfect" starting location, it helps to understand how biomes are created. A region's biome is a factor of elevation, drainage, rainfall, and temperature, as explained in this old forum thread for 40d.
Elevation comes first. Any terrain with an elevation of 0-99 is ocean. Any terrain with an elevation of 300-400 is mountain terrain. All other biomes lie in between these two extremes.
Drainage and rainfall determine the next division.
Rain | ||||||
Drain | 0-9 | 10-19 | 20-32 | 33-65 | 66-100 | |
0-32 | Desert | Grassland | Savanah | Marsh | Swamp | |
33-49 | Wasteland | Shrubland | Forest | |||
50-100 | Badlands | Hills |
Finally, temperature. Glaciers seem to form at a temperature of around 0. Just above that temperature, forests become taiga, and all other terrain becomes tundra. Unfortunately, temperature is harder to affect directly in world gen because according to Toady One, it's affected by both latitude and elevation. At the other end of the temperature scale, biomes become tropical at around 65+; generally speaking you'll need Hot and Scorching temperatures.
Worlds | |


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Dia Diagram Editor
Versatile diagramming tool
Welcome to Dia's homepage. Dia is a GTK+ based diagram creation program for GNU/Linux, MacOS X, Unix, and Windows, and is released under the GPL license.
News! 2011-Dec-18: Version 0.97.2 has been released. Visit the Download page to get your copy! (Download shortcuts: Windows,Mac OS X) |
Dia is roughly inspired by the commercial Windows program 'Visio,' though more geared towards informal diagrams for casual use. It can be used to draw many different kinds of diagrams. It currently has special objects to help draw entity relationship diagrams, UML diagrams, flowcharts, network diagrams, and many other diagrams. It is also possible to add support for new shapes by writing simple XML files, using a subset of SVG to draw the shape.
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Download Dia and try using it; tell us what you think of it (visit the Contact page), including to report bugs if you find them. You can even read the Development page to find out how to contribute to the code.