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Today in History
Today is Sunday, Feb. 24, the 55th day of 2013. There are 310 days left in the year.
Today's Highlight in History:
On Feb. 24, 1868, the U.S. House of Representatives impeached President Andrew Johnson following his attempted dismissal of Secretary of War Edwin M. Stanton; Johnson was later acquitted by the Senate.
On this date:
In 1582, Pope Gregory XIII issued a papal bull, or edict, outlining his calendar reforms. (The Gregorian Calendar is the calendar in general use today.)
In 1803, in its Marbury v. Madison decision, the Supreme Court established judicial review of the constitutionality of statutes.
In 1821, Mexican rebels proclaimed the "Plan de Iguala," their declaration of independence from Spain.
In 1863, Arizona was organized as a territory.
In 1912, the American Jewish women's organization Hadassah was founded in New York City.
In 1920, the German Workers Party, which later became the Nazi Party, met in Munich to adopt its platform.
In 1938, the first nylon bristle toothbrush, manufactured by DuPont under the name "Dr. West's Miracle Toothbrush," went on sale. (Previously, toothbrush bristles were made from animal hair.)
In 1942, the SS Struma, a charter ship attempting to carry Jewish refugees from Romania to Palestine during World War II, was torpedoed by a Soviet submarine; all but one of the 769 refugees on board perished.
In 1961, the Federal Communications Commission authorized the nation's first full-scale trial of pay television in Hartford, Conn.
In 1983, a congressional commission released a report condemning the internment of Japanese-Americans during World War II as a "grave injustice."
In 1988, in a ruling that expanded legal protections for parody and satire, the Supreme Court unanimously overturned a $150,000 award that the Rev. Jerry Falwell had won against Hustler magazine and publisher Larry Flynt.
In 1993, Canadian Prime Minister Brian Mulroney (muhl-ROO'-nee) resigned after more than eight years in office.
Ten years ago: Seeking U.N. approval for war against Iraq, the United States, Britain and Spain submitted a resolution to the Security Council declaring that Saddam Hussein had missed "the final opportunity" to disarm peacefully and indicating that he had to face the consequences. A powerful earthquake in China's western region of Xinjiang killed at least 263 people, according to the U.S. Geological Survey, and injured at least 4,000.
Five years ago: "No Country for Old Men" won Academy Awards for best picture, best director and best screenplay adaptation for Joel and Ethan Coen and best supporting actor for Javier Bardem (HAH'-vee-ayr bahr-DEHM'); Daniel Day-Lewis won best actor for "There Will Be Blood," while Marion Cotillard (koh-tee-YAHR') was named best actress for "La Vie en Rose." A suicide bomber struck Shiite Muslim pilgrims south of Baghdad, killing at least 56 people. Cuba's parliament named Raul Castro president, ending nearly 50 years of rule by his brother Fidel. Ralph Nader announced a fresh bid for the White House on NBC's "Meet the Press."
One year ago: Secretary of State Hillary Rodham Clinton, in Tunisia for a conference on Syria, blasted Russia and China as "despicable" for opposing U.N. action aimed at stopping the bloodshed in Syria. Jan Berenstain, 88, who with her husband, Stan, wrote and illustrated the Berenstain Bears books, died in Solebury, Pa.


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Scouting Report
Jonah Ballow
Knicks vs. Wolves – Madison Square Garden
When: Sunday| 5:00 PM
Where to Watch: MSG Networks
Where to Listen: ESPN 98.7 FM
Team Reports
New York: Following a loss to Chicago on Friday, the Knicks relinquished their lead in the Eastern Conference. At 19-7, New York suffered its second loss of the season at home and faces some challenges with injuries along the frontline. Rasheed Wallace has a stress reaction in his left foot and he is listed as day-to-day. New York's veteran center joins Marcus Camby on the sidelines while Amar'e Stoudemire continues to work through rehab with no official timetable for his return. At the conclusion of Sunday's contest, the Knicks will board a plane for Los Angeles and prepare for a three-game road trip starting with a matchup against the Lakers on Christmas Day.
Minnesota: Kevin Love, Ricky Rubio, and a revamped roster has the fans in Minnesota thinking about a return to the postseason for the first time in nine years. The team acquired Brandon Roy, Chase Budinger, Andrei Kirilenko, Dante Cunningham, Louis Amundson, Greg Stiemsa, and Alexey Shved as part of a major overhaul this offseason. Unfortunately, the Wolves have dealt with a myriad of injuries to key players. Rubio just returned from a serious knee injury suffered last year, Roy is struggling with his knee and out until late December, Budinger will not return until March, and Love (eye) has been ruled out of Sunday's game. Remarkably, Minnesota has weathered the storm while compiling a 13-11 record by winning its last five of seven games.
Last Time Out
New York: Four were ejected and the Knicks fell 110-106 in a wild contest at the Garden on Friday night.
Minnesota: The Wolves notched one of their biggest wins in recent memory with a 99-93 triumph over the Thunder on Thursday night.
The Numbers Game
The Knicks average 104.9 points per game in 13 home contests and they own an 11-2 mark this season at Madison Square Garden.
Match-up to Watch
Tyson Chandler vs. Nikola Pekovic
Pekovic may have exceeded the Wolves expectations as he continues to impress in his third season in Minnesota. The big man is averaging a career-best 16 points and 7.9 rebounds per game this year. With Tyson Chandler patrolling the paint for New York, this specific matchup will be intriguing on Sunday night. Chandler will have to force Pekovic out of the box and limit his second chance opportunities. Additionally, the Knicks Defensive Player of the Year needs to stay out of foul trouble, especially with the lack of frontcourt depth on the New York bench.
What to Look For
Love's absence is a serious setback for the Wolves. He is the team's leading scorer, rebounder, and the reigning 3-Point Contest champion. Without Love in the lineup, Minnesota will look to find a rebounding presence at other positions as they rank No. 5 in the entire league by ripping down 45.6 boards per game. The Wolves have several offensive weapons and gifted passers, including Rubio and Shved, an up-and-coming guard tandem in the backcourt. The real issue for Minnesota will be its ability to match the Knicks on the offensive side of the floor. New York will be highly motivated to end the long homestand on a positive note after falling to Chicago on Friday. The Knicks are averaging 102.9 points per game this season and expect a big offensive performance from the home team and Anthony.
For more news and notes on the team follow the New York Knicks and Jonah on Twitter.

subset: commoncrawl


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Further growth for Cumbrian food industry
Last updated at 08:44, Wednesday, 29 May 2013
Cumbria's booming food-and-drink sector is poised for further growth, following a decade of relentless expansion.
The foot and mouth crisis of 2001 proved to be the impetus for niche producers to set up in response to growing demand for high-quality produce of known provenance.
Newcomers such as Hawkshead Relish and Country Puddings have prospered alongside larger, long-established, food-and-drink businesses such as McVitie's and Cavaghan & Gray in Carlisle, and Cockermouth brewer Jennings Brothers.
Now Cumbria Chamber of Commerce has launched the Food and Drink Growth Network to foster further expansion.
Sixty businesses were expected at the launch at the North Lakes Hotel, Penrith, last Friday. In the end more than 100 attended.
John Grainger, managing director of Invest in Cumbria, believes the sector has a bright future.
He said: "The key word is provenance.
"You can take it back to the time of the foot-and-mouth outbreak in 2001.
"Within the last 10 years there has been an explosion of enterprise in the food-and-drink sector. The latest food scare around horse meat [in supermarket beef products] has encouraged consumers to look at the provenance of food even more.
"We have seen an upturn in the use of family butchers.
"Consumers are more aware of where food comes and are prepared to pay a slight premium for that level of quality."
The Food and Drink Growth Network will act as a focal point for businesses looking to grow, improve and increase competitiveness.
It is part of the Chamber of Commerce's Cumbria Business Growth Hub and Rural Growth Network.
Lori Whinn, managing director of Rural Foodies, who mentors fledgling food producers, spoke at the launch, as did food promoter Phil Keenan of Thoroughly Food.
Some of Cumbria Business Growth Hub's advisors have specialist knowledge of the food-and-drink industry.
They include Adrian Luckham, who has experience of running a food business and the business consultancy Way Ahead.
He said: "I hope the Growth Hub can help food-and-drink businesses understand where their target market is.
"It's all about getting the product to the consumer.
"The food-and-drink industry in Cumbria is fantastic because you never know what you might find, there are some real hidden gems."
Also attending the launch was Peter Johnston, managing director of Origins Caterers, a seven-week-old venture in Kirkoswald that has taken advice from the Growth Hub.
He said the fledgling enterprise had benefited from having an external mentor who could question what the business was doing.
He agrees that increased public awareness of where food comes from is helping the sector in Cumbria.
Mr Johnston added: "There is an awful lot of interest in provenance. People are more knowledgeable about it.
"Our commitment to any client or customer is that we will source produce locally.
"In Cumbria there is such variety and an opportunity to use smaller suppliers that are more committed to customer service and quality than a national chain might be. The challenge for any caterer or food business is to deliver that quality at the right price."
Food and Drink Growth Network events planned include workshops, social-media training, food-photography training, and advice on packaging.
More information is online at www.cumbriagrowthhub.co.uk.
First published at 08:42, Wednesday, 29 May 2013
Published by http://www.cumberlandnews.co.uk


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My slowest was about 256kb on the day they released Portal for free. I have a 60mb service.
the slowest i've seen a download on steam in the last 3 -5 years is 1.1mbps for me2
Redeem code is in multiple places. If the developer puts it in the game, it's in a game menu. However, you can consistently find it by: Guide Button > Markeplace > Redeem Code. As for your wireless issue, you really should be running wired. It's faster, more stable and more secure. But if you insist on wireless, then you should maybe look at your settings to see why you are only at G. The Xbox 360 S (and the Wifi adapter for the old Xbox 360) are both at N.
how am i supposed to download a download only game i only have a code for and no disc from anywhere other than teh redeem code option in xbox dashboard which is so cleverly hidden away? code did not work in xbox.com. i started the download before i started drinking that night and it finished near the end of the night. maybe it had more to do with the xbox s having wireless g and not wireless n.


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CitationsCommittee on Genetics, American College of Obstetricians and Gynecologists (2009). Preconception and prenatal carrier screening for genetic diseases in individuals of Eastern European Jewish descent. Obstetrics and Gynecology, 114(4): 950–953.Committee on Genetics, American College of
Obstetricians and Gynecologists (2005, reaffirmed 2010). Screening for
Tay-Sachs disease. Obstetrics and Gynecology, 106(4):
893–894. Other Works ConsultedHaslam RHA (2006). Degenerative diseases of the
central nervous system. In FD Burg et al., eds., Current Pediatric Therapy, 18th ed., pp. 388–392. Philadelphia: Saunders
Elsevier. Neudorfer O, Kolodny EH (2004). Late-onset Tay-Sachs
disease. Israel Medical Association Journal, 6:
107–111.Ropper AH, Samuels MA (2009). Inherited metabolic diseases of early childhood section of Inherited metabolic diseases of the nervous system. In Adams and Victor's Principles of Neurology, 9th ed., pp. 922–926. New York: McGraw-Hill.
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1-1 of 1 results for Author: sadayuki ujihashi (sorted by Publication Date, showing all)
The Impact of Technology on Sport II
Sport technology has to be seen from the holistic, as well as inter- and transdisciplinary point of view. Product development requires close collaboration between engineers, athletes, sports scientists, and business managers. It requires an in-depth understanding of engineering disciplines, life...
Published October 11th 2007 by CRC Press


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Justice Minister Shakib Qortbawi attaches a No Smoking sign at the Justice Palace in Beirut, Lebanon, Thursday, April 26, 2012. (The Daily Star/Mohammad Azakir)
Before heading to lunch or going out for drinks, find an ashtray and stub out that cigarette. Starting today, smoking is prohibited in all enclosed bars, restaurant and cafes in Lebanon in accordance with Law 174, which passed exactly one year ago.
The anti-tobacco legislation has already been the target of much criticism, from some who believe that the government should focus on more critical matters to those who warn that the ban will hurt the hospitality sector and the country's wider economy.
The associations of restaurants and hotels have cried foul, urging that the law be amended and threatening to take escalatory steps if it is not.
In a statement issued over the weekend, the Restaurants Owners' Association described the law as poorly drafted, "paving the way for uneven implementation and corruption, in addition to negatively impacting the service and tourism sectors."
"We will be starting a strike and [will] shut our businesses ourselves instead of letting the government close them down," Shebel Abu Shebel, a member of the association, told MTV television station Saturday, adding that stronger measures over the coming weeks should be expected if demands aren't met.
Meanwhile the head of the Hotel Owners' Association, Pierre Ashkar, warned that thousands of employees could be let go if nargileh cafes are forced to shut down due to lack of business.
"Around 1,000 cafes in Lebanon are specialized in nargileh and if they stop working, they will have to let 10,000 employees go," Ashkar said.
The association has called for excluding entertainment businesses from the ban, including pubs, nightclubs and nargileh cafes and has asked that indoor smoking be allowed in venues with proper ventilation and age restrictions.
The ban on smoking in bars, restaurants and cafes is the final stage of the law that also saw the banning of smoking in all public buildings – government offices, hospitals and institutions of education – and on public transport.
Enforcement in these areas has so far been patchy.
The National Tobacco Control Program says that no data exists on whether any fines have been handed out.
Responsibility for enforcing the law falls to members of various bodies – the Internal Security Forces, the Health Ministry, the Consumer Protection Offices at the Economy Ministry, the Tourist Police and municipal staff.
Civil society is also doing its bit, with volunteers from the "Tobacco Control Citizen Watch" vowing to keep restaurant owners, and the official observers themselves, on their toes.
But in a recent Ernst and Young study, commissioned by the Association of Restaurant Owners, 82 percent of respondents, themselves owners of hospitality venues, believe the law would lead to an increase in corruption.
Out of total revenues, which exceed $735 million, the association said the revenues of restaurants, pubs and nightclubs could decline by $282 million, putting the figure at 7.1 percent of Lebanon's GDP.
The Ernst & Young study also claimed that around $46 million would be lost in tourism spending, putting over 2,600 full time jobs in danger of being phased out.
But Rania Baroud, from the non-governmental organization the Tobacco Free Initiative, said that enforcing the law could actually improve restaurants' revenues. "People adjust to the ban within two weeks and resume going to restaurants and bars normally. The revenues of the Turkish tourism sector in fact increased 5 percent after the smoking ban was implemented," she said.
Smoking rates in Lebanon are among the highest in the world, with 42 percent of men and 27 percent of adult women smoking.
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Geographical Information Systems in Archaeology
Part of Cambridge Manuals in Archaeology
- Authors:
- James Conolly, Trent University, Peterborough, Ontario
- Mark Lake, University College London
- Date Published: May 2006
- availability: In stock
- format: Paperback
- isbn: 9780521797443
Other available formats:
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Geographical Information Systems (GIS) is a rapidly developing archaeological method which is moving from the domain of the computer specialist into that of the broader archaeological community. This comprehensive manual on the use of GIS in archaeology explores the concept of GIS and illustrates how it can be adapted for practical use. Examining issues such as spatial databases, data acquisition, spatial analysis, and techniques of visualization, the book is an essential tool for both students and professional archaeologists.Read more
- Archaeological examples included throughout
- Introduces underlying theoretical principles as well as practical methods and techniques
- Highly illustrated
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Product details
- Date Published: May 2006
- format: Paperback
- isbn: 9780521797443
- length: 358 pages
- dimensions: 248 x 174 x 20 mm
- weight: 0.64kg
- availability: In stock
Table of Contents
1. Introduction and theoretical issues in archaeological GIS
2. First principles
3. Putting GIS to work in archaeology
4. The geodatabase
5. Spatial data acquisition
6. Building surface models
7. Beginning exploratory data analysis
8. Spatial analysis
9. Map algebra, surface derivatives and spatial processes
10. Regions: territories, catchments and viewsheds
11. Routes: networks, cost paths and hydrology
12. Maps and digital cartography
13. Maintaining spatial data.
Instructors have used or reviewed this title for the following courses
- Introduction to Geographic Information Science
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From the daily archives: Wednesday, May 28, 1997
On May 28, 1997
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The image came to me late at night: a faceless medical building in an obscure section of Beverly Hills, comings and goings suggestive of macabre secrets. Toss in political correctness gone creepily wrong, the smarmiest side of academia, organized and disorganized crime, and Delaware at his sharpest. The story is catalyzed by [...]
Read an ExcerptRead the first three chapters from The Golem of Hollywood.
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The WDSc 5.1.2 redbook has just been published and can be downloaded from: http://ibm.com/redbooks/abstracts/sg246961.html Just a little light reading for everyone's weekend : ) Don Yantzi Technical Release Lead WebSphere Development Studio & WebSphere Development Studio Client for iSeries IBM Toronto Lab Phone: (905) 413-4476 IBM internal: IBMCA(yantzi) - Internet: yantzi@xxxxxxxxxx
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CIO Advisory Committee
The CIO Advisory Committee exists for the purpose of advising the University of Tennessee Health Science Center (UTHSC) Chief Information Officer (CIO) and providing a conduit for the exchange of information between the UTHSC Office of Information Technology Services and the students, staff, and faculty at all UTHSC locations.
The Committee meets monthly and approved minutes are posted for viewing. Also posted are the current regular roster, Terms of Service, and the Bylaws. All documents require Adobe Reader to open.
Working groups were established to help determine IT priorities for the campus, utilizing these Working Group Guidelines. The committee revises its IT Priorities List annually.
Membership 2014-15
|Member Name
|Area Represented
|Jan van der Aa, PhD
Ex-Officio Member
|Vice Chancellor and CIO
Information Technology Services
|Larry Tague
|College of Graduate Health Sciences
|Daniel McGarry
Vice Chair
|College of Nursing
|Anna Montgomery
|College of Dentistry
|Sajeesh Kumar, PhD
|College of Health Professions
|Stephen Adams, MD
|College of Medicine - Chattanooga
|Travis Turner
|College of Medicine - Knoxville (Graduate School of Medicine)
|Yan Cui, PhD
|College of Medicine - Memphis
|Jennifer Williams
|College of Pharmacy
|C. Judith Nyabando, EdD
|Academic, Faculty & Student Affairs
|Jada Williams
|Alumni Affairs & Development
|La'Keith Miller
|Executive Vice Chancellor Office (Facilities Admin.)
|Charles Cossar
|Finance & Operations
|Paul Gahn
|Library & Biocommunications Center
|Patricia Page
|Office of Research
|Phyllis Richey, PhD
|Faculty Senate
|Rakesh Patel
|Student Government Association
|Netia Watson
|Employee Relations Committee (ERC)
|Ramona Jackson
|Exempt Staff Council (ESC)
Advisory Committee Links
Contact Us
Department of Information Technology Services
877 Madison Ave
Memphis, Tennessee 38163
Phone: 901-448-2222
Fax: 901-448-8199


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Conratulations to Sheriff -Elect Brown and Smitty ! Job well done by two outstanding gentlmen !
Don't see then again i'm old Dual score's for Howell or Ocean in SL today.
Trumps or Liquid assests ? Either way tables are expensive ! lol


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Anguil Environmental Systems, Inc.
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based in Reggio Emilia, ITALY
Comet spa is an international business founded on the strength of a world-renowned brand. With 3 production sites, many branches and numerous distributors, Comet works in more than 70 countries around the globe.In addition to Italy, where the company has consolidated its position of absolute prestige, Comet is particularly active in the European and international markets; ...
Exothermics Inc.
based in Toledo, OHIO (USA)
Exothermics is a leading source of reliable, high-efficiency industrial heat exchangers including, air to air, plate type, stainless steel, and dimple plate heat exchangers. Each offers robust construction, outlasting many competing products and delivering the lowest total cost of ownership. Designed and built by highly-certified and highly-trained employees, Exothermics ...
AWAS GmbH Bayern Wastewater Treatment Plants
based in Oberhaching, GERMANY
AWAS has been in research, development and manufacturing of industrial waste water treatment plants for over 30 years and owns several patents and patent rights. We manufacture: - Flotation plants (DAF) - Emulsion splitting plants - Oil-Water separators, patented AWAS Galaxie Vortex separators - Filter systems - Wash water recycling plants, wash halls - Bio reactors We ...
based in Indianapolis, INDIANA (USA)
CentraSep is the ONLY single-motor, vertical, self-discharging, automatic centrifuge. CentraSep features a proprietary, patented design-a high-speed solid/liquid industrial centrifugal separator. CentraSep combines an innovative bowl/blade clutch design with a single AC motor and variable frequency drive to automatically extract particulate from virtually any liquid at a ...
Need help finding the right suppliers?
Let the XPRTs do the work for you


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Artist Collection: (6 of 25)< Previous | Next >
Tags: landscape, painting, impressionism, nature, silver birch trees, green, yellow, expressionist, luminescent, valzart
- + MOUSE OVER image to zoom in
- + CLICK to enlarge
ramblers retreatby valerie anne kelly
- Medium
- Traditional
- Artist Notes
- "Rambling through the sunlit day espying creatures along the way." A painting portraying the healing color of green and inspired by the light and beauty of the Norfolk Broads UK.
- Contact Artist Send Artist an Email
More about valerie anne kelly
- Location
- norfolk, england
- Artist Biography
- Valerie Anne Kelly-aka-valzart is an award winning Artist, Photographer and Writer. Her work has been sold and exhibited all over the world,she has painted many commissioned pieces and is presently creating illustrations for worldwide textile brands and book covers. Whatever the medium o ...


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The Westin Resort & Spa, Cancun
Heavenly Spa by Westin™
White sand beaches, the lull of the ocean, clear blue skies, and temperate sunlight—these are Cancun's most fundamental pleasures. At The Westin Resort & Spa, Cancun, we've incorporated these elements into the serene atmosphere of our Heavenly Spa by Westin™. Our mission is to use all five senses to soothe the mind and body while uplifting the spirit.
Our four terrace cabanas and five beachside palapas (straw huts) let you pair your favorite spa experience with soothing sea breezes and spectacular views of turquoise waters. Also on the beach is our authentic Temazcal hut, offering the cleansing experience of an ancient Mayan steam bath.
Indoors, the spa's beautiful facilities are permeated with the calming aroma of white tea, our signature scent. Enjoy a facial, or other treatment of your choice in our six luxurious treatment alcoves. Or unwind on your own in the sauna and steam rooms or our relaxation lounges complete with Jacuzzis. In-room massages are also available for those times when you just want to cocoon.
Upon arrival you'll be offered an energizing snack packed with antiviral and cancer-fighting antioxidants. Then take your pick of a tremendous array of soothing services, from revitalizing facials to therapeutic body wraps to massage for any need, and much more. We're always exploring new ways to create complementary spa experiences, so speak to the staff about our latest packages and multi-treatment offerings.
Please note that all prices listed here are in U.S. dollars, do not include gratuities, and may be subject to change. Be sure to notify the spa staff before your treatment if you are pregnant or have any health concerns.
Reservations: We encourage guests to schedule appointments in advance to ensure a preferred treatment or therapist is available. Same-day bookings and walk-in appointments are always welcome, based upon availability. All reservations must be secured with a major credit card and telephone number.
Cancellation policy: We require 24 hours notice for changes or cancellations. Please keep in mind that arriving late for a service may require us to shorten the length of the treatment, with full charges applied, so as not to inconvenience other guests.
Take time: Give yourself plenty of time so you can enjoy the steam, sauna or whirlpool prior to your services. This relaxes and warms the muscles, which will aid in the therapeutic benefits of all our treatments and services. We suggest arriving 30-60 minutes prior to your first service. Respect yourself and others by turning off communication devices prior to entering the spa, locker rooms, fitness and treatment areas.
Heavenly Spa by Westin™
|Pevonia Botanica
|Специальные помещения:
|Six indoor treatment rooms, in addition to our outdoor massage huts, Jacuzzi, traditional Mexican Temazcal sauna and steam bath heated with volcanic rocks, plus a fully equipped fitness center.
|Часы работы спа:
|Monday - Saturday 8:00 AM - 10:00 PM; Sunday 8:00 AM - 8:00 PM
|Позвонить в спа:
|(52)(998) 848 7468
Body Treatments
Black Mud
This unique thermal mud—rich in 350 vitamins, minerals, and enzymes—is renowned for relieving aches, pains, and cramps. This superb mud also boosts the body's immune system and relieves fatigue and stress, leaving you invigorated and fit for life.
- Стоимость: 50 minutes/$110
Known for its cosmetic smoothing and contouring properties, organic green coffee extract aids in the reduction of water retention and skin's imperfections. A high-concentration serum is applied to problematic areas followed by a body mask.
- Стоимость: 50 minutes/$100
Back Ritual
Your back, neck, and shoulders are scrubbed with a warm Aromatic Moor Mud rich in natural vitamins, minerals, and enzymes. The back is then wrapped in a heated herbal therapy pack, followed by a muscle-relaxing balm and a revitalizing massage.
- Стоимость: 35 minutes/$70
Heavenly Body
In this antioxidant nourishing wrap, a luscious, tropical fruit-extract cocktail reveals skin that is toned, supple and soft. This treatment provides an antidote to everyday stress, plus cellular restoration and environmental protection for the skin.
- Стоимость: 50 minutes/$110
Enjoy immediate cooling and desensitizing benefits as burning, itching, and stinging sensations are alleviated. This healing treatment decreases your skin's temperature and provides hydration. Ideal for soothing painful sunburns.
- Стоимость: 50 minutes/$100
Chocolate Indulgence
Enliven your senses with an aromatic wrap that feeds the skin with unique mixture of chocolate oils.
- Стоимость: 50 minuts/$110
General Services
Mom 2be
Embrace peace with this relaxing massage which will stimulate your lymphatic and circulatory system to discourage water retention.
- Стоимость: 50 minutes/$100
Hands & Feet
Heavenly Hands
Select the aromatherapy blend that suits your mood and indulge in complete relaxation.
- Стоимость: $45
Heavenly Feet
Ground yourself with a moisturizing paraffin treatment for your feet.
- Стоимость: $45
Massage Services
WestinWORKOUT® Massage Treatment
Improve your performance, endurance, and recovery time with a special deep massage and stretching, designed for an athlete's specific needs.
- Стоимость: 50 minutes/$110; 80 minutes/$135
This gentle, relaxing massage is designed to stimulate metabolism, strengthen growing muscles, and encourage deep sleep.
- Стоимость: 25 minutes/$50
Submit to this unique experience and connect with your inner being as you are soothed and comforted by heated basaltic stones. The warming energy will embrace you as tensions melt away in a celestial and magical ambience.
- Стоимость: 50 minutes/110; 80 minutes/$135
Heavenly Massage
A heated compress invites back muscles to release tension before your choice of distinct essential oil blends are massaged into the body. Relaxation comes from the harmonious balance of scent and touch.
- Стоимость: 50 minutes/$110; 80 minutes/$135
Moonlight Romance
Share this enchanting escape with someone special: this couple's massage inspires renewed unity. The perfect way to celebrate a special occasion or simply cherish your loving harmony.
- Стоимость: 50 minutes/$220; 80 minutes/$280
In this uplifting experience for body and spirit, two therapists devote their full attention to you, working their magic in harmony. Our signature Heavenly Spa massage is followed by a relaxing facial and foot massage.
Pure, perfectly round crystals are heated and rolled over the body for a deeply penetrating massage that's utterly calming and completely absorbing.
- Стоимость: 80 minutes/$135
Specially-designed techniques combine to stimulate and oxygenate deep muscle tissue. Some stretching, targeting specific areas, will release tensions and pain for a feeling of ease and lightness.
- Стоимость: 50 minutes/$110; 80 minutes/$135
This uplifting massage focuses on the areas that tend to retain the most stress and tension—your back, neck, and shoulders.
- Стоимость: 25 minutes/$60; 50 minutes/$100; 80 minutes/$130
Skin Care Services
This advanced defense against aging is a safe alternative to Botox, replenishing your skin with pure caviar and pearl extracts. A luxurious clay thermal mask helps improve elasticity and increase cellular oxygenation and the skin's suppleness.
- Стоимость: 80 minutes/$140
This deep-hydrating facial is suitable for all skin types, including mature skin. Its high concentration of collagen to calm, firm, and tone the skin is ideal after sun exposure.
- Стоимость: 50 minutes/$110
This fundamental treatment is designed to provide a deep cleansing through the application of cleansers and exfoliates. This process includes pore extractions, followed by a face, neck, and shoulder massage and a soothing mask to heal the skin.
- Стоимость: 80 minutes/$135
This personalized treatment is formulated especially for the needs of a man's skin by counteracting the signs of aging, razor burn, and sensitivity. Visible results will promote a healthy, youthful skin with a rejuvenated appearance.
- Стоимость: 50 minutes/$110
Completely customized care for men that leaves the face thoroughly cleansed, deeply hydrated, and protected. This experience includes a face, neck, and scalp massage for total relaxation and skin rejuvenation.
- Стоимость: 50 minutes/$110
Deep moisture and rich nourishment culled from essential antioxidants and vitamins counter signs of aging and neutralize environmental stresses on the skin.
- Стоимость: 80 minutes/$140
Heavenly Exfoliation
Keep your skin looking its best and most radiant with your choice of three Pevonia exfoliation treatments. As delightful aromas entice the senses, the body is gently massaged, impurities and dead skin cells are removed, and circulation is stimulated.
- Стоимость: 25 minutes/$60
Express Facial
Ideal for when you need a quick boost, this treatment leaves the skin looking fresh, clear, and truly radiant. A mask is included, along with thorough cleansing, toning, and moisturizing to suit your skin type. Extractions are not included.
- Стоимость: 25 minutes/$60
Experience the refreshing and restoring benefits of this deep hydrating facial, for dry, sensitive, or normal skin.
- Стоимость: 80 minutes/$140
Spa Packages
Let your thoughts and worries slip away as you enjoy the unique pleasures and revitalizing sensations of our healing Temazcal, Mayan, and Reiki treatments.
- Стоимость: 220 minutes/$360
Experience deep levels of relaxation and serenity with a Relax massage, a Renewal facial, and Heavenly Hands and Feet.
- Стоимость: 130 minutes/$220
Let thoughts and worries slip away as you submit to the unique pleasures and revitalizing sensations of our healing heavenly massage and our renewal facial. Walk out with a light step and youthful glow.
- Стоимость: 125 minutes/$360
Pamper yourself, mind and body. This indulgent package contains the blissful combination of our heavenly massage, heavenly body, and renewal facial. Leave feeling completely renewed.
- Стоимость: 180 minutes/$300
Chakra Balance
This gentle treatment focuses on the central Chakra system, freeing the body of emotional blocks and stress-produced afflictions and allowing energy to flow. It reinforces your immune system and leaves an overall feeling of peace and harmony.
- Стоимость: 50 minutes/$80
Mayan Temazcal Bath
The temazcal bath ritual purifies your mind and body and feeds your spirit in an extraordinary setting. An ancient ceremony with therapeutic purposes, the ritual combines herbs, flowers, and music in a rustic cocoon and enchantingly beautiful lagoon.
- Стоимость: Per person $200; Couples $230
Mayan Princess Purification
Conjuring ancient ritual and tradition, we have created an experience that mingles pleasurable sensations and healing ingredients–aromatic incense, healing plants, and a tropical fruit scrub and mask–to leave you feeling healthy and transformed.
- Стоимость: 80 minutes/$135
In this ancient healing technique, hands are positioned on specific areas where energetic centers or chakras are located.
- Стоимость: 50 minutes/$80
Heavenly Hands and Feet
Select the aromatherapy blend that suits your mood and indulge in complete relaxation. A warm coating of paraffin will soothe and soften the skin while a therapist massages your temples and ears, and your escape is complete.
- Стоимость: 50 minutes/$110
This traditional technique uses moderate to strong pressure on acupuncturing points along energy pathways to stimulate and restore balance to the body.
- Стоимость: 25 minutes/$50; 50 minutes/$100; 80 minutes/$135
Mayan Treatment
Prepare for a deeply relaxing journey to the past. Warm cotton compresses containing herbal mixtures are applied to your body's energy meridians, then massaged into your muscles. Please reserve this treatment at least 24 hours in advance.
- Стоимость: 80 minutes/$135


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You can now invite anyone to meet at your favorite Starbucks.
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40 year old man | Rancho Park, CA, USA | Seeking women 26-40 within 30 miles of Los Angeles, CA
Happy and at ease, I thrive in the presence of...
Happy and at ease, I thrive in the presence of positive, genuine and motivated people. An authentic and off-the-beaten-path human experience has always been of interest and way of life for me. Having the courage to listen to the inner voice, the heart-place, and taking action, is paramount to keeping things real. I live life for the now….never taking anything for granted. Life is a gift, I choose to share it with individuals who are equally enthusiastic. Driven and accomplished, I have a solid work ethic. Whatever it is that I take on, be it a project, relationship, sport, or play, I do it at 110%. That said, maintaining a healthy life balance is something I am keenly interested in and always looking to improve upon. So, sometimes sleeping in, doing nothing, and simply "being", is the way of the moment. If you have any other thoughts on this subject, I am all ears... I place a high value on my family and friends. My tribe, community and people are such a huge part of what make life what it is. It is important that my lady share this appreciation. Adventurous and open-minded, I am always up for taking chances and trying new things. I have a passion for travel, dining, music, arts, the outdoors, and anyting that gets the adrenaline going. Fitness and competition is a significant aspect of my life. I enjoy training and competing in crossfit competitions (I have entered 6 this year). I believe a good match occurs when both parties bring new perspectives and experiences to the table. Together, we expand our universe. I seek a woman with strong, yet humble, self-confidence and self-respect. My lady takes her health and fitness seriously. She treats her family and friends with respect. She leads with her heart, and speaks and acts with loving kindness. My lady is on a spiritual journey and committed to exploring this further. My woman has a wicked sense of humor and she knows it :). She LOVES to have fun, and is passionate in every sense of the word. I love a gal who is serious about her business, an expert at her trade (whatever that may be) and knows how to step up when its game time. Yet, knowing how to let it all go and not taking herself too seriously is equally as important. Laughing is one of my favorite pastimes, so I hope you aren't afraid of letting your hair down and getting silly...are you?
Camping , Coffee and conversation , Cooking , Dining out , Movies/Videos , Museums and art , Music and concerts , Exploring new areas , Nightclubs/Dancing , Performing arts , Playing cards , Playing sports , Religion/Spiritual , Shopping/Antiques , Travel/Sightseeing , Volunteering , Watching sports , Wine tasting
Baseball, Basketball, Billiards / Pool, Bowling, Dancing, Football, Martial arts, Other types of exercise, Running, Skiing, Soccer, Swimming, Tennis / Racquet sports, VolleyBall, Walking / Hiking, Weights / Machines, Yoga
I exercise 5 or more times per week.
Don't display my sign
I like Birds, Cats, Dogs, Exotic Pets, Fish, Horses
I grew up with animals and love them...but do not currently have any.
Middle of the Road
Love playing at the beach, in the ocean, or on a hike on the local trails. I enjoy ski trips to Mammoth and surf excursions to Costa Rica. Sometimes breaking away to the desert for some much deserved poolside and spa r&r is bliss
The University of Arizona, Tucson, AZ
A huge music lover, I'm into anything that moves me (rock, hip-hop, country/blue grass, eclectic, jam, classic, jazz/blues, pop, electronica). I will jump at the chance to check out a new artist live- is one of my favorite things to do on this planet
The possibilities are endless... I train 5 days a week in a competitive crossfit program. Another long time favorite is a morning yoga class, then breakfast in Venice, followed by a leisurely stroll through the canals...
Currently reading "Relentless" by Tim Grover. Phenomenal book on mental toughness in all aspects of life. One of favorites of all time is "Lone Survivor". I could not put this book down, and it inspired me in a life-changing way.
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What he is looking for
|5'10" (177cms)
|5'0" (152cms) to 5'10" (177cms)
|Body type:
|Athletic and toned
|Slender, Curvy, Athletic and toned
|No preference
|No preference
|No Way
|No Way
|Social Drinker
|Never, Social Drinker
|Financial / Accounting / Real Estate
|No preference
Commercial real estate business.
|No preference
|No preference
|Have kids:
|Yes, and they sometimes live at home (2)
|No preference
|Wants kids:
|Probably not
|No preference
|I'll tell you later
|No preference
|Spiritual but not religious
|No preference
I experience life as a spiritual journey.
|No preference
|Bachelors degree
|Some college, Associates degree, Bachelors degree, Graduate degree, PhD / Post Doctoral


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Select Local Merchants
Berlin RacewayRead MoreFrom its beginnings as a plain dirt track in 1950, the Berlin Raceway has transformed in the intervening decades into one of the country's most challenging and esteemed short tracks. A 7/16-mile paved oval, with 13-degree banking in the turns and 9-degree banking on the straightaways, the track regularly hosts races for various types of autos, ranging from four-cylinder vehicles to super and outlaw late models to Big Wheels with rocket engines attached. Drivers follow in the tire marks of renowned racers, including Tim Steele and Jack Sprague, some of who are chronicled in the track's hall of fame.2060 Berlin Fair DrMarne, MI US
AJ's Family Fun CenterRead MoreThe revs of go-kart engines, the delighted shrieks of putt-putters, and the cracks of batting-cage chops have banded together in joyous harmony for more than 20 years at AJ's Family Fun Center. Each of the three locations caters to the entire family with a wide range of exciting attractions. Though activities differ slightly at each outpost, thrill seekers of all ages can participate in age-appropriate activities, such as Sprint Karts for ages 16 and up, mini golf for adults and kids, and arcade games for those old enough to have received the value of a token lecture from a wise elder.4400 Ball Park DrComstock Park, MI US
Placid Wake ParkRead MoreAccording to an interview with mLive, Placid Wake Park's owner Scott Ferwerda can easily pinpoint the crown jewel of his wakeboarding park: a Sesitec System 2.0 cable that spans a 700-foot manmade lake. "When you hit a rail and fall," Scott explains, the boat "has to come back and get you." Not so with cables. "With this, the operator sees you fall, stops the cable immediately, you swim 5 feet over to get a rope, and 10 seconds later, you are back up hitting the same things you just tried." Riddled with optional obstacles, such as a pyramid playfully named the Ninja Turtle and a hydraulic rail on which to hide from creepy dragonflies, the cable lake is only one of Placid's two aquatic bodies. The boating lake branches out into three prongs, where wakeboarders, surfers, and waterskiers have the option to conquer currents the old-fashioned way—pulled by a boat and whistling the song from Steamboat Willie. The park welcomes athletes of all ages and abilities, offering rental equipment and lessons with pro wakeboarders to individuals as well as families. On the shore, spectators can lounge on at picnic tables shaded by umbrellas or snag a front seat to the action atop an observation deck, and landlubbers can stay active by digging for seashells at the sand volleyball court.11252 84th AveAllendale, MI US
Blast FactoryRead MoreAt the Blast Factory, inflatables cushion the tumbles of sock-clad youngsters as parents and trained supervisors look on. Kids climb up and glide down multicolored slides or crawl through the mouth of a tall inflatable dragon in search of cavities. Along with open play, The Blast Factory hosts two-hour private parties, during which up to 25 kids can enjoy 90 minutes of private inflatable fun and 30 minutes in a private celebration room. Each party also can include add-ons such as pizza, popcorn, cotton candy, and soda.5870 Safety Drive NortheastPlainfield Township, MI US
The Lost City- HollandRead MoreAn indoor family-entertainment center, The Lost City invites fun seekers young and old to enjoy a wide range of gaming venues, including a sprawling laser-tag arena, an indoor mini-golf course, an arcade, and a Highway 66 mini-bowling alley. Lasers fly through fog and atmospheric lighting within a multilevel laser-tag arena that spans 5,000 square feet. Participants wear vests and wield phasers as they rack up scores that are then recorded on their individual scorecards. The Lost City?s nine-hole mini-golf course has a Gobi Desert theme, complete with palm trees, pyramids, and camels. To continue a competitive night with friends, head to the 10-pin bowling lanes, which switch between classic woodgrain and a black-lit road theme, or guests can challenge their hand-eye coordination at an arcade with air hockey and redemption games.12330 James St.Holland, MI US
Harvest Moon AcresRead MoreCleaved through 5 acres of towering corn stalks, Harvest Moon Acres' sprawling corn maze sends journeyers through an ear-walled labyrinth filled with disorienting twists and tricky clues that lead the way. The maze shares the expansive farm with a variety of other kid-friendly, bucolic attractions, including a petting zoo and an outdoor fun zone. There, guests soar down a 40-foot slide or take aim at targets from behind the pumpkin slingshots, originally used to knock enemy witches from their brooms during World War II. Hayrides surround guests with the cool, fragrant autumn air as they cruise over the 20-acre grounds on a soft bed of hay. Harvest Moon Acres also sells pumpkins, indian corn, and other fall staples for those looking for seasonal decorations or ingredients for autumnal recipes.18725 M-40 Hwy.Gobles, MI US


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Things to see and do - L'islet-sur-mer
Leaving for Canada
Church of Our Lady of Perpetual Help
Church of Our Lady of Perpetual Help : Michelin's recommendations
The fieldstone church was built in 1768 and enlarged in 1884, when the façade was refurbished and twin steeples added. The statues in the niches of the façade, representing St. John the Baptist on the left and St. Francis of Assisi on the right, are the work of Amable Charron, who also designed the cornices of the interior. The main altar was fashioned by François Baillairgé and the tabernacle by Noël Levasseur. Six paintings by Antoine Plamondon grace the walls. The Stations of the Cross were carved in 1945 by Médard Bourgault, a native of Saint-Jean-Port-Joli.
Useful Information
- Address : 15 r. des Pionniers-Est CDN - Islet-sur-Mer G0R 2B0G0R 2B0Islet-sur-Mer
- Phone : (418) 247-5103


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Final countdown: One more day until the Oscars
STARS ON STAGE: Stars of the year's biggest films stepped out on Oscar's stage late Friday.
Never mind it was just a rehearsal.
First it was Kristen Stewart and Taylor Lautner of "Twilight." She wore skinny jeans, sneakers and a tan V-neck top. He sported a black shirt, gray pants and a slim tie. A stage manager told them where to go and suggested they walk arm in arm.
They approached the microphone and producer Adam Shankman gently scolded, "No folded arms!" Stewart quickly dropped her arms by her side.
The two teen stars ran through their lines, joking with each other between takes. Stewart chewed gum throughout.
"Love the gum," Shankman joked.
Next was Sigourney Weaver, who wore a striped blouse with jeans — and the towering stilettos she plans to wear Sunday night. The 60-year-old actress practiced making her entrance again and again, concerned about how her long dress might hinder her approach.
"Let me try it pretending I have a dress on," she said, facing an audience of stand-ins and show workers inside the Kodak Theatre.
The three-time Oscar nominee marveled at the view from the stage.
"This is such a nice, small theater," she said. "I don't think I've ever taken this long at rehearsal before."
She was followed by Bradley Cooper and Gerard Butler, who both wore jackets, slacks and credentials. They stepped out confidently, and Cooper seemed genuinely excited when a trophy model handed him the prop Oscar.
"This is great," he said.
Finally, "Avatar" star Sam Worthington took the stage. Wearing a hooded sweatshirt and horn-rimmed glasses, the Australian actor was unflappable. He rehearsed his lines, and the theater went dark. One more day of rehearsals and then the real deal.
GETTING CREATIVE: Dana Delany, Kathy Najimy, Ty Burrell and Rachael Leigh Cook were among the celebrities who recorded public service announcements for the Creative Coalition Friday at Haven 360, an Oscar-week suite comprising gifting, parties and support for the arts.
Creative Coalition co-president Tim Daly is directing the public service announcements, which show stars singing the ABC's, as part of the organization's lobbying efforts to increase funding for arts education in public schools.
The videos will be presented at the Creative Coalition's Arts Advocacy Day in Washington, D.C. next month, along with a companion book, "Art Soul," that features portraits of actors and their handwritten messages about what art means to them, Daly said.
"This is about keeping the arts in education," he said. "Kids learn their letters by singing. The arts make learning interesting and fun."
Haven 360 guests were also treated to hand massages from Olay, gifted with Elle jewelry and invited to peruse Backstage Creation's "celebrity retreat," where they could pick up a free $5,000 trip to Moorea, Botox and Juvederm treatments worth $900 from celebrity surgeon Dr. Frank Ryan, and luxury luggage from Dooney Bourke.
AP Entertainment Writer Derrik J. Lang contributed to this report.


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American Idol
Watch Kree Harrison Sing "Stronger" in American Idol 2013 Girls Semi-Finals
Kree Harrison performs Faith Hill's "Stronger" in American Idol 2013 girls semi-finals.
More on Kree...
If you believe the online buzz, Kree Harrison is considered to be one of, if not THE, American Idol 2013 frontrunner. It's no big surprise, as the 22-year-old country singer who hails from Texas but lives in Nashville, Tennessee, has blown away the judges with her stellar vocals.
"I would be very afraid if I were any of the other girls here tonight," judge Nicki Minaj said after her Las Vegas performance of "Up to the Mountain".
As many have said over the years, country singers do tend to have heartbreaking tales to tell, and this beautiful girl has a doozie. She lost her dad to an airplane crash when she was only 12 years old, and her mother died in a car accident only four years later. She took to songwriting to express her emotions, and you'll need some tissues handy to check out her song, "You Would've Wanted It That Way".
Singing and performing is certainly old hat to Kree, as she even went on The Rosie O'Donnell Show when she was eight to perform and returned three more times. In fact, Lyric Street Records caught wind of her talent and signed her at the age of 12. Already knowing she didn't want to be Disney-esque but more country, she split with the label. Perhaps she was destined for Idol, as she certainly sailed through to the Top 20.


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Best student blogs of 2012
Blog entries definitely worth a moment of your time
The best student blogs of 2012 aims to bring together a selection of blogs that have inspired me or friends, furthered our understanding of the world, bettered our student experience or offered us new ways of seeing university life.
Guardian Student Bloggers
And as 2012 draws to a close what better time is there to bring the best of the best into one place?!
At the start of 2012 The Guardian newspaper began a student blogging program whereby you can submit an idea for a blog entry to their editors and if they like it you are given advice and support in publishing your piece.
The best blog entries from 2012
There are currently 112 entries all of which vary in usefulness and relevance. Of those we selected thirteen worth a mention!
The blogs themselves cover a vast array of topics including:
- Accommodation, music, nightclubs, tuition fees
- Depression, drugs, alcohol, other mental health issues
- Fashion, shopping, food, obesity, anorexia
- Revision, plagiarism, all-nighters, deadlines
- Fees, student unions, politics, riots, marches
Tell us about your own blog
Our criteria for choosing the best blog entries are to do with how closely they align with our website aims – The promotion [of anything] that exists to better the lives of students and further their education…
So without further ado and in the order they were first published…
The Guardian Student Bloggers
Exams make our hands sore
We spent most of our time writing on computers during our teenage years so why did we have to do all of our exams on laptops? Oddly, given the choice, the vast majority of students preferred a pen over a keyboard!
What do students want in a club?
A lot of students would argue it isn't where you are that counts, it's who you are with! But a list of dos and don'ts for any club is an interesting read. How does your favourite Loughborough Club fare?
Could social media ruin your career prospects?
Earlier this year another wave of articles came to light that showed employers were using social media and peoples care-free attitude to posting private content to help them make decisions. Recently Facebook and Twitter have tightened up their security settings so this should be a problem no longer! Make sure your Facebook page is secure and protect your tweets if you are concerned!
The importance of Freshers week
Bristol university considered shortening freshers week but there was a student out-cry and so the plans were shelved. Clearly Freshers week is more than just a bit of fun!
Who helps students with mental health problems?
Universities all across the country are seeing rises in the number of cases of students diagnosed with depression and anxiety. If you are affected by either of those and study at Loughborough, visit our Loughborough Heads Up page!
What can you do with a 2:2? and Why a 2:2 isn't the end of the world
Some people immediately panic and think their entire degree is wasted or worse still; that they themselves are failures. Take a look at these two articles written from two different viewpoints.
How do you spend your student loan?
We've all heard the story of the person who blew their entire loan in one day. There is one on every campus! But should the loans companies take more responsibility for issuing loans? Or should students just learn to manage money better?
Ten things I wish I had known before I started my dissertation
Ten helpful nuggets of information to bear in mind if your dissertation is looming large!
The art of procrastination
'Students are hard-wired to waste time' but never fear, there is sound scientific reasoning to explain it and also to help you! Plus heres an e-book I once read that was well worth my time reading.
Surviving an all-nighter and What happens to your body if you don't sleep
Between them these two articles focus on the best ways to successfully pull an all-nighter while also focusing on the longer term health effects of sleep deprivation
How to treat your brain during revision time
A neuroscience student uses his knowledge to help students memorise information including the importance of sleep, controlling your emotions and taking regular breaks.
And that concludes the round-up of the best student blog entries of 2012. If you would like to feature on this page or would like us to give your own blog a mention, comment below or send us a message!
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text:
A portable medical analyzer comprising a sampling module with a sample port for receiving body fluid, an assay sensor module for analysis of the body fluid, an analytical detector module with detection of information from the assay, and a communications module for transferring the information to a remote location via a wired or wireless network.
1. A portable medical analyzer comprising:
a lancet within a cartridge;
a lancet driver for advancing said lancet to puncture tissue;
a sample pathway for receiving at least one body fluid directly from a tissue puncture formed by said lancet, said pathway contained within the cartridge;
at least one assay sensor housed in said cartridge, said sensor adapted for at least one assay for said body fluid received by said sample pathway;
an analytical detector comprising at least one signal processor and circuitry for processing of signals from at least one detector corresponding to said assay sensor, said detector adapted to detect information from said assay; and
a communication module coupled to said signal processor, said communication module comprising a transmitter and receiver in communication with an information management system;
wherein a pressure seal on the cartridge is broken by a vacuum when interfaced with the analytical detector, to transfer the body fluid to the assay sensor.
2. A portable medical analyzer according to
said communication module comprises a transmitter adapted to transfer said information to a remote location.
3. A portable medical analyzer according to
said communication module comprises a receiver adapted to communicate with a remote location.
4. A portable medical analyzer according to
communication module has a transmitter using one of the following for transmission of information to a remote location: infrared or radio frequency signals.
5. A portable medical analyzer according to
communication module includes at least one of the following: a processor, display, RF chip, antenna, an operating system, RAM, DRAM, or a PCMCIA interface.
6. A portable medical analyzer according to
said communication module is adapted to couple with said analytical detector via a standard port.
7. A portable medical analyzer according to
said transmitter is adapted to include at least one interface chosen from radio frequency, infrared and standard ports.
8. A portable medical analyzer according to
an information storage unit for storing said information locally on said portable medical analyzer.
9. A portable medical analyzer according to
10. A portable medical analyzer according to
This is a continuation of application Ser. No. 09/981,483, filed Oct. 16, 2001, now U.S. Pat. No. 6,966,880 the entire disclosure of which is incorporated herein by reference.
The present invention relates to portable medical devices. More particularly to a point-of-care ("POC") medical diagnostic system with communication capabilities.
Over the past 30 years, the average life expectancy of North Americans has increased by approximately 13 years, contributing to a rapid increase in the number of people over the age of 65. Thus, there has been a dramatic growth in total health care spending as the population ages. As a result, the use of screening and monitoring diagnostics for early intervention, improved treatment and monitoring has become an important aspect of health care.
Technological advances have facilitated the development of easy-to-use, rapid diagnostic devices which can be used in a POC setting, closer to the patient, and that have the ability to pick up disease at an earlier stage. POC testing is attractive because it rapidly delivers results to the medical practitioner and enables faster consultation with the patient. Thus, early diagnosis can enable the practitioner to commence treatment sooner, perhaps leading towards improved patient outcomes. Examples of POC tests include blood chemistry, such as glucose, hematology, immuno-diagnostics, drugs of abuse, serum cholesterol, fecal occult blood test ("FOBT"), pregnancy, and ovulation. In addition many new types of analytics now being carried out in the DNA arena (such as DNA based assays, immuno assays, proteomics and genomics) which are likely candidates for POC testing.
One such example of the potential benefit from a portable medical analyzer in the use of DNA testing is to help doctors prescribe medicine tailored to the particular patient's genotype. Gene-array chip technology determines a patient's genetic information, which a health-care provider may use to classify the patient in particular genotypes. Medications respond differently depending on the particular patient's genotype. By matching the most effective medication for a particular genotype, the patient may receive superior care by avoiding adverse reactions, while maximizing drug efficacy.
A portable medical analyzer provides the additional benefit of facilitating the remote patient monitoring of a patient's medical status. The effectiveness of monitoring systems depends not only on the range of tests reported and their accuracy, but also on the frequency and rapidity of information gathered regarding the patient's health status. A portable medical device can run a range of tests, which cover most of the tests required for diagnosis or therapy monitoring, including blood gases, electrolytes, hematocrit, and various metabolites such as glucose.
Combining biochemical parameter results from the POC device with physiological parameters (such as ECG, respiration rate, temperature and blood pressure) permits integration of vital signs and blood chemistry on a real time basis, for better disease management. Results can then be tracked over time for trend analysis. Portable medical analyzers also have application in the clinical research setting for remote patient evaluation in post surgical recovery, drug therapy and novel pharmaceutical testing using the remote communications ability.
Current POC devices do not provide an integrated solution for patient self-testing to sample acquisition, testing, analysis and connectivity to remote centralized healthcare. Accordingly it is the object of this invention to provide a portable, highly integrated, multi-parameter measurement instrument with IT solutions for data collection, transmission, analysis and on-line decision support. This is achieved by an integrated approach to sample acquisition, a miniaturized multi-parameter low cost test strip or "cartridge," a companion portable instrument and an information solution for connectivity via a wired or wireless network.
In accordance with the invention, a method and apparatus for utilizing a portable medical analyzer is provided. The method comprises obtaining a body fluid transmission of the fluid to a cartridge, the cartridge comprising at least one assay sensor module, positioning the cartridge into an analytical detector module, where positioning the cartridge breaks a pressure seal on the cartridge causing the body fluid to flow to an assay sensor on the cartridge, using the analytical detector module to detect the results of the assay sensor, connecting the analytical detector module to a communication module, and transferring the results from the analytical detector module to the communication module.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the invention, as claimed.
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate several embodiments of the invention and together with the description, serve to explain the principles of the invention.
Reference will now be made in detail to the exemplary embodiments of the invention, examples of which are illustrated in the accompanying drawings. Wherever possible, the same reference numbers will be used throughout the drawings to refer to the same or like parts.
In accordance with the present invention, a portable medical analyzer is described. One aspect of the present invention is a portable medical analyzer capable of performing a variety of diagnostic tests. Portable may refer to the self-contained nature of the analyzer. Portable may further refer to a hand-held format for the analyzer. As illustrated in
In one aspect consistent with the present invention, sampling module 110 is a one-step, painless, ergonomic blood sample acquisition module, which provides capillary blood for introduction into an integrated assay sensor module 120. Assay sensor module 120 may be a highly integrated, low-cost, disposable diagnostic cartridge supporting parallel testing of multiple established and emerging diagnostic parameters from body fluids including but not limited to capillary blood, venous blood or blood gases. Analytical detector module 130 employs a modularized hardware technology combining appropriate detection and communication technologies. Analytical detector module 130 module may accept a disposable cartridge or series of disposable cartridges for the analysis of body fluids. Communication module 140, with bi-directional wireless connectivity to an information infrastructure which can provide a gateway to laboratory and clinical information systems, has an information infrastructure for integrating the use of decentralized diagnostic technologies within general patient care processes.
Each type of module can be a removable interchangeable component allowing for module packaging and disposability. Various combinations of sampling, assay sensor, and analytical detector modules could accommodate a very wide range of diagnostic tests, from blood glucose testing to DNA typing. Any of these combinations would be able to utilize a common communication and information infrastructure adding to the flexible nature of this architecture.
Sampling Module
In a portable medical analyzer, sampling module 110 can receive fluids using a variety of methods. The sampling module can acquire a number of body fluids, including but not limited to blood. The fluid can be a liquid and/or a gas. The sampling acquisition port of the portable medical analyzer captures body fluid for testing. The port can receive fluids from a variety of means of sample acquisition and or transfer, including but not limited to, lancing, injection, pipette, intravenous, and catheter. In a non-limiting embodiment, a lancet punctures the skin and a sample collection port, which can be positioned to correspond with the wound created by the lancet, channels the blood to a sample test area or a sample storage chamber. Such channeling can be passive (gravity, capillary flow, etc.) or active (aspiration, vacuum, etc.).
The lancet may be advanced and/or retracted by a variety of mechanical, electrical, electromechanical, piezoelectric, and electromagnetic, or a combination of these types of driving mechanisms. Mechanical driving mechanisms can contain a spring, cam or mass actuators to drive the lancet. These include cantilever springs, diaphragms, coil springs, as well as gravity plumbs to actuate the lancet. Typically, the device is pre-cocked, or the user cocks the device. The device is held against the skin and the user mechanically triggers ballistic launch of the lancet. Other types of driving mechanisms may use electrically based driving and triggering methods, electrical, electromechanical, piezoelectric, and electromagnetic, or a combination of these types of driving mechanisms.
In one embodiment of the invention, a sampling module 110 and assay sensor module 120, from
The driving mechanism can be combined in the sampling module 110, assay sensor module 120, or analytical detector module 130. It is desired that the lancet in a module be dispose of with the module for biohazard purposes. It is desired that an expensive mechanism, i.e. electronic, be built into the non-disposable portion of the module e.g. communication module 140 or analytical detector module 130, where as an inexpensive driving mechanism, i.e. cantilever spring may be built into the disposable module. In the embodiment where the sampling module 110 and assay sensor module 120 are combined on one cartridge, such an expensive driving mechanism can be contained on analytical detector module 130, as discussed in
Alternatively, a sampling module 110 may be used to draw blood into a sample acquisition port, which may be separate from the assay sensor. Such a modular configuration provides flexibility in linking one sampling module 110 with several assay sensors. Blood may thus be allocated to each of the assay sensors thereby, requiring only one lancing event and reducing the donor's discomfort.
Alternately, a sampling module 110 can be coupled to an assay sensor module such that the interface is standardized. For example the Memory Stick Duo� (Sony, Japan) provides a modular solution where the sampling module with a Memory Stick� interface can receive assay sensor modules configured to digital media standards.
Driver 40 plugs into cavity 20 of cartridge 10. Driver 40 may be disposable and attached to the cartridge or reusable and attached to the assay sensor. Reservoir 22 has a narrow opening sample acquisition port 14 on an ergonomically contoured surface 26 for collecting the blood from a donor, such as from finger 50 lanced by lancet 16. Reservoir 22 may fill passively through gravity, or capillary flow, or actively through aspiration or vacuum collect the blood sample.
The cartridge 10 can transport the blood sample through small passages (not shown) using active pumping or passive microfluidics, to a specific localized assay sensor 28 for analyzing the blood, which corresponds to a corresponding location on the analytical detector module 130. The analytical detector module 130 can comprise chemical, physical, optical, electrical or other detecting means of evaluating the blood sample by the assay sensor module 120.
Cartridge 10 is loaded in a slot 32 within analytical detector module 130. The driver 40 contains the driving mechanism 38, which is capable of advancing, stopping, and retracting the lancet 16. The slot 32 also contains the detector 48 for evaluating the blood analysis of the assay sensor 28 on the cartridge 10, which corresponds to detector 48 when the cartridge 10 is loaded into the slot 32. Alternately, cartridge 10 can be designed with an array of testing locations, which contain a variety of assays sensors and correspond to an array of detectors on the analytical detector module 130. Pins 34 on slot 32 provide electrical contact between the cartridge 10 and the analytical detector module 130 to enable identification of the type of assay sensor, and quality control issues (e.g., expiration date of cartridge). Alternatively, cartridge 10 can be in mechanical contact with analytical detector module 130 locking the cartridge 10 in place and puncturing the cartridge 10 to break a vacuum seal and begin fluid flow for calibration and create a pressure differential for capillary forces to pull the body fluid sample.
In one embodiment of the invention, the cartridge may be developed on a Memory Stick� (Sony Electronics, Japan) digital media standard interface. Alternative embodiments contemplate other digital medial standard interfaces including but not limited to Compact Flash�, MulitMedia Card�, Secure Digital�, SmartMedia�, or any other removable portable device. The cartridge is of an ultra compact design that has a standard size and connectivity specifications based on the respective standard interface. The removable cartridge can be inserted into an assay detector module 130 with a slot and connector corresponding to the standard for PC cards or Memory Stick Duo� detachable cartridge.
Assay Sensor Module
As used herein, the term "assay sensor" refers to a substrate or location for conducting body fluid analysis, such as but not limited to a biochemical assay. The assay sensor module 120 provides an analytical testing platform for the fluid sample. In a non-binding embodiment, the sampling module and assay sensor are bundled together. Alternatively, the assay sensor may be a separate component. A sample is transported through the assay sensor module to particular assay sensors, through a network of microtubes using active or passive transport.
Blood coming into the cartridge via sample acquisition port 340 is stored in reservoirs 420 so that it can accumulate to volumes appropriate for the relevant assay to be performed. Reagents necessary for the analysis are stored and shielded in reservoirs 380 prior to their use. A system of valves (not shown) keeps the reagents and sample fluid confined to appropriate paths in the cartridge 300. The blood and reagents are transported via active or passive transport through micro tubes 320 to assay sensors 420. The micro tubes 320 may be forked to mix the blood and reagents prior to reaching assay sensors 400. Alternatively, the blood and reagents can mix upon contact with the assay sensor.
Analytical Detector (AD) Module
In the portable medical analyzer, the AD module 130 evaluates the assay sensor in the assay sensor module via detectors, which are associated with the assay sensors. The AD generates signals corresponding to information or characteristics of the assay sensors. The AD module may include signal processing devices and circuitry for the rapid processing of the signals generated by the array of detectors, which correspond to the array of assays. A variety of detectors, including electrical, electrochemical, optical or mechanical can be used to detect results from tests on the assay sensor module. In one embodiment, the AD module can interface with a standard port on a portable computing device such as a laptop computer, a personal digital assistant ("PDA"), or other portable computing device, including but not limited to a Palm™ Handheld, Handspring™ Visor or Compaq iPAQ�. Standard ports include PCMCIA, serial, parallel, USB, IEEE 1394, and other computer connectivity standard ports.
A non-limiting embodiment of the analytical detection module 130 contemplates a PC card platform, such as a Personal Computer Memory Card International Association ("PCMCIA") card or Handspring™ Springboard™ Module. PC cards have standard thicknesses, design and pin assignments. The PC card physical characteristics include a 68 pin physical interface, length 85.6 mm, width 54.0 mm , and a thickness of either 3.3 mm, 5.0 mm, or 10.5 mm, depending on type. PC cards can include a slot for a Memory Stick� or other modular standard for sampling and assay sensor modules, thereby allowing detection and measurement of the assays on the PC card. In one embodiment, many different assays can be performed in the one detection area. The information detected by the analytical detectors contains results from each of these different assays. The thin versatile PC card will be able to both accept the cartridge and plug into a standard communication module for performing tests.
By virtue of the modularity of assay sensing module 120, the analytical detector can be adapted for a wide variety of applications. In addition, by virtue of the modularity of analytical detector module 130, it can plug into a variety of host communication or computational platforms, ranging from PDAs to bench top systems. By utilizing the various combinations of assay sensors and analytical detectors, measurement systems can be configured that range from those suitable for personal use such a glucometer, to instruments for POC hospital application, or even laboratory measurements.
Communication Module
In the portable medical analyzer, a communication module 140 can control both local (onboard) and remote (external) communication. The receiver can be adapted to receive instructions and/or data from external sources. The transmitter can be adapted to transfer the information read from the detector to external databases and systems in remote locations. The communication module 140 can also comprise a display adapted to show the information read from the detector locally to a user via an LCD or other visual indicator. The remote transmission component can be a wireless component. The communication module 140 plays the dual roles of controlling local and remote communication.
One embodiment of communication module 140 can be a PDA, such as a Palm™ PDA, a Handspring™ Visor, or a Compaq iPac�. Communication module 140 can comprise of a standard PDA hardware and software including a processor, display, RF chip, antenna, and an operating system, which may be expanded by using some type of PC card technology. The PDA can be programmed with software to read information from analytical detector module 130, and transmit the information remotely using an industry standard protocol for communication of medical information.
Communication module 140 can have a local storage unit in which the information collected can be stored, such as a localized RAM, i.e. DRAM containing a database of information. The information can also be sent to and stored on a remote database. The remote database can be part of Laboratory Information System, used to manage the information in central and reference laboratories. The remote database can display the information to a clinician, who in turn can analyze the information and send back to the user of the device instruction or comments on the results. Any of these functions can also be performed by a local database. In one embodiment, a communication module in a PDA can transmit and receive information through radio frequency ("RF"), infrared ("IR"), or docking on a cradle as is well known in the art of standard ports for computer peripherals.
In one embodiment, the communication module can direct information to a screen that displays test results to a user. In another embodiment, the module can direct information through a bi-directional wireless system. The communication module 140 can communicate to the user, and communicate with an outside system as well. This connection can be made to a lab, a database, a clinical trial or a Laboratory Information System. The Laboratory Information System is an information management system. The term "information management system" refers to a system that can be used to manage the data between the portable medical analyzer and a centralized means for collecting and processing information for functions including but not limited to qualified user authentication, quality control, quality assurance, quality reporting, clinical processes, such as low impact on workflow, result review, decision support, and business processes (such as submitting information for billing generation, demonstrating cost-effectiveness, supporting practice guidelines, and direct marketing). The information and instructions transmitted to the portable medical analyzer can be directed to the particular user based on personal identification and security information.
Technically, the analyzer has many key features including reliability, security and confidentiality, content distribution, and functionality distribution. (such as a application service provider). The analyzer can be connected to a central system, or it can stand alone. Once connected to a system, synchronization can take place. At the remote database end of the system, security and confidentiality are supported by creating authorization and authentication schemes to limit the access to data. The functionality distribution includes the creation of multi-tier disruption models, which may include localized computation or centralized server based computation. The functionality of the system is adaptive based on the availability of local or remote resources.
In one embodiment, the data collected can be used for blind testing. A brokering system can be structured based on the collected personal medical records. The confidentiality of the system allows individuals to sell their medical data anonymously to customers. The customers can then use the data to develop medical technology or evaluate a heath care system.
In another embodiment, a patient management system can be adapted to application distribution and information management. The system uses the portable medical analyzer and provides health care organizations with information integration and access to administrative, data management and decision support applications at the point of care.
In another embodiment, the analyzer can be adapted to receive instructions from an administration system to automate processes such as calibration. The device can be in constant communication with a central hospital server system. At regular intervals the server can send a communication to the device that calibration is necessary. In one embodiment, the user can take a calibration cartridge and insert it into the device for calibration. The server can then either confirm that the device is calibrated or tell the user the device must be recalibrated manually.
In another embodiment, the analyzer can be used for viewing of historical data such as previous results and patient trends. The analyzer can download past patient results, or store past patient results locally, and after testing show the patient not only the current results but also where they fall within historical trends.
In another embodiment the analyzer can be a part of the Universal Connectivity Standard for Point-of-Care, for which further information may be forward at www.poccic.org. Using the connectivity standards, the device may be connected to both other devices and major medical or hospital systems. The communication can take place via an IR port, wireless networks or through connected phone lines.
In another embodiment, an analyzer connected to an LIS can compare results from diagnostic tests run in the laboratory of full-size analyzers and develop correlation tables between results from the portable medical analyzer and the laboratory results.
Method of Use
In another embodiment, the flow calibration fluid is simultaneously with body fluid sample. Analytical detector 130 can be connected to communication module 140 through a standardized port. When connected, communication module can provide extra mechanical and electrical power to analytical detector 130. Once powered, analytical detector 130 can quantify the results of the chemical analysis on the assay sensor module (step 440). The results are then transferred from analytical detector module 130 to communication module 140 through the standard pin connections (step 450). Communication module 140 can display the results locally for a user and/or transfer the results immediately or at a later time to a central database in a remote location. The entire process, from lancing to results may take as little as a few minutes.
Although what has been described is aimed at analysis of body fluids, this concept is easily extended. Analytical detector modules could be developed to provide other diagnostic measurements such as ECG, or temperature etc. These measurements would then take advantage of the same communication module and communication network to transmit information.
Other embodiments of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the invention being indicated by the following claims.
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Vedad Ibisevic and Chinedu Obasi each bagged a brace as Hoffenheim ended a seven-game winless run with a thumping 5-1 victory over Europa League semi-finalists Hamburg.
Ibisevic wasted little time getting off the mark, scoring in the second and 11th minutes as the hosts jumped out into an early 2-0 lead. Obasi made it 3-0 after 31 minutes before Robert Tesche trimmed the deficit after 65 minutes. Obasi finished off the game with his second in the 73rd minute before Sejad Salihovic made it five 13 minutes from time. Hamburg's Tolgay Arslan was sent off for violent conduct in the final minute.
The win moves Hoffenheim onto 38 points in 11th place, while Hamburg, who travel to Fulham for the return leg of their Europa League semi on Thursday, stay seventh on 48 points.
Freiburg shock the champions
Cedrick Makiadi's first-half goal proved enough as Freiburg boosted their chances of staving off relegation with a surprise victory over reigning Bundesliga champions Wolfsburg.
Makiadi scored the only goal of the game in the 38th minute to help Freiburg continue their impressive run at home, where they have collected 10 points in the last four home matches.
And they were able to take advantage of defeats by those around them and jump into 14th place, three points above the drop zone. Wolfsburg remain in eighth place on 46 points and have no hope now of making it into Europe next season.


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For Tuesday, January 29, 2013
POSTED: 01:30 a.m. HST, Jan 29, 2013
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A 7-0 vote for Okino, for dubious reasons

A 7-0 vote for Okino, for dubious reasons
Mayor Kirk Caldwell ultimately made the right call in withdrawing former City Councilman Gary Okino's name from consideration for the city's Ethics Board of Appeals. Okino asserted that he has "no tolerance for homosexuality," which is not the expression of equanimity you want from someone weighing ethical behavior. Login for more...