text:
Catherine Verfaillie
|The neutrality of this article is disputed. (April 2011) (Learn how and when to remove this template message)
Catherine M. Verfaillie (Dutch: [vərfɑi]; born 1957) is a Belgian molecular biologist and professor at the Katholieke Universiteit Leuven (Leuven, Belgium). Her work on the ability of adult stem cells to differentiate to different cell types has garnered controversy due to accusations of poor laboratory practices and fabrication of data by members of her laboratory.[1]
Education and career[edit]
Born in Ypres, she obtained an M.D. from the Katholieke Universiteit Leuven in 1982, after which she specialized in internal medicine. In 1987 she departed for the United States as a research fellow at the University of Minnesota. She worked in the lab of Phillip McGlave in hematopoiesis and stromal control of hematopoietic stem cells, in 1991 becoming a professor in the Department of Medicine, becoming a full professor in 1997.[2]
Verfaillie was Director of the Stem Cell Institute at the University of Minnesota (U.S.) from 1998 until 2006. In a widely noted paper in 2002, she claimed a specific type of adult-derived stem cells (termed multipotent adult progenitor cells (MAPC)).[3][4]
She is a Professor of Medicine in the Division of Hematology, Oncology and Transplantation of the University of Minnesota's Medical School. She holds the Anderson Chair in Stem Cell Biology and the McKnight's Presidential Chair in Stem Cell Biology. She now leads the Stamcel Instituut te Leuven (SCIL) (E: Stem Cell Institute Leuven) at the Katholieke Universiteit Leuven in Leuven, Belgium. She is a member of the Advisory Board of the Itinera Institute think-tank.[citation needed]
Controversy and aftermath over stem cell falsification[edit]
The report was immediately sensational in scientific circles given that it was the first report of adult-derived stem cells to have properties previously ascribed to embryonic stem cell only. The report was immediately also heralded by conservative lawmakers opposed to embryonic stem cell research as proof that such research is not needed.[5] Skepticism surrounded the announcement from the beginning: Stuart Orkin from the Harvard Medical School noted, "If the cells are what she says -- and I have no reason to dispute that but no one has demonstrated it yet -- it's pretty remarkable. For people interested in tissue regeneration, this would be the cell to work with."[6]
Verfaillie was noted to immediately benefit from the interest in adult stem cells with her lab size and funding immediately doubling.[7] The discovery was considered so ground-breaking that she received several accolades in the first few years after the initial report. The British biomedical publication New Scientist declared it as the "ultimate stem cell discovery".[8] Problems with working with MAPCs proved difficult to several laboratories who were keen to co-operate in expanding the use of MAPCs. In a report in Nature, Dr. Rudolf Jaenisch at MIT was quoted by Nature stating that "I have not seen any convincing data showing that anyone has repeated the chimaera experiment, so I don't think this part of it is true",[9] referring to the claim by Verfaillie that MAPCs when injected into mouse embryos contribute to all tissues.
The same article also quoted Orkin as saying that the material transfer agreement (MTA) for procuring these cells were so restrictive that his group refused to work with them. First reports on potential problems with Verfaillie's group's work came in early 2007 when New Scientist reported that the 2002 Nature paper had some of the images appear in a second paper published at about the same time.[10] The article also revealed duplication of images in a 2001 paper on blood, authored by Verfaillie's trainee, Morayma Reyes, and that a patent application for the MAPCs was licensed to a company called Athersys, based in Cleveland, Ohio. A series of investigations into at least three instances of data duplication/ fabrication by the University of Minnesota followed, which eventually concluded in October 2008 that Morayma Reyes had fabricated data in the 2001 paper.[citation needed]
The panel criticized Verfaillie's laboratory for "poor scientific method and inadequate training and oversight for this research". It contacted Blood and asked the journal to retract the paper. The investigators also found discrepancies with images in a second paper from Verfaillie's laboratory, published in the Journal of Clinical Investigation in 2002. Those problems did not rise to the level of academic misconduct, the university said. It did not find fault directly with Verfaillie, but Tim Mulcahy[who?] concluded that the "message here is that everyone needs to fulfill their responsibility to the public and to science".[11][12]
In response to the investigation at the University of Minnesota, Nature instituted their own investigation to the 2002 controversial paper and Verfaillie was allowed to make a Corrigendum to the original paper,[13] which did not acknowledge fabrication of data, and claimed that the original observation still held. The issue raised by Rudolf Jaenisch and others regarding the non-reproducibility of the blastocyst injection data was not addressed by the reviewers of Verfaillie. In early 2010, a third paper by the group in the American Journal of Cell Physiology was withdrawn due to "data presented have now been shown to be unreliable.[14] This was again prompted by an investigation by 'New Scientist.
Aftermath of scandal and move back to Belgium[edit]
Verfaillie moved to the Katholieke Universiteit Leuven at the height of the controversy in 2008[15] but retained her position at the University of Minnesota. She has continued to defend her work and gave a list of publications that have proven the utility of MAPCs, albeit without addressing the criticisms of how the key parts of her work could not be reproduced by other labs. In 2007, she collaborated with Irving Weissman at Stanford University to demonstrate that MAPCs could produce blood cells although she did not address the key claims of her original 2002 paper.
Verfaillie is on the editorial board of journals such as Experimental Hematology and PLOS one.
- José Carreras-prize
- Damasheck-prize
- 2004, Lección Conmemorativa Jiménez Díaz Prize
- 2005, Vlerick Award
- ^ New York Times report on Dr. Catherine Verfaillie
- ^ Eckfeldt CE, Mendenhall EM, Verfaillie CM., The Molecular Repertoire of the "Almighty Stem Cell, Nature Rev Mol Cell Biol, 6, pgs. 726-737 (2005);
- ^ Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, Verfaillie CM., Pluripotency of mesenchymal stem cells derived from adult marrow, Nature, 4 July 2002; 418 (6893): pgs. 41-9
- ^ Yuehua Jiang, Balkrishna N. Jahagirdar, R. Lee Reinhardt, Robert E. Schwartz, C. Dirk Keene, Xilma R. Ortiz-Gonzalez, Morayma Reyes, Todd Lenvik, Troy Lund, Mark Blackstad, Jingbo Du, Sara Aldrich, Aaron Lisberg, Walter C. Low, David A. Largaespada & Catherine M. Verfaillie, Pluripotency of mesenchymal stem cells derived from adult marrow, Nature, 2002, June 14; 447, pgs. 880-1
- ^ [1]
- ^ New York Times article on Dr. Verfaillie
- ^ www.pulitzer.org
- ^ New Scientist website
- ^ [2]
- ^ www.stemcellcommunity Archived 2007-07-30 at Archive.is
- ^ www.newscientist.com
- ^ jobs.chronicle.com Archived 2011-07-08 at the Wayback Machine.
- ^ Nature magazine website
- ^ http://ajpcell.physiology.org/cgi/content/full/00324.2008/DC2
- ^ "Archived copy". Archived from the original on 2012-07-12. Retrieved 2011-07-08.


text:
Maths ability develops earlier than thought
New research from the University of Chicago has identified the period between a child's third and fourth birthday as the key stage for development of children's grasp of maths.
Children from disadvantaged social backgrounds, though less skilled in verbal communication by the time they start school, are shown to be as adept as other children when it comes to numbers and figures.
In the paper issued by the university's Early Childhood Initiative, Professor Susan Levine said young pupils were likely to learn maths better if teaching was less verbally orientated.
"Often when children cannot respond correctly to the verbal mathematics problems presented in classrooms, it is assumed they lack an understanding of mathematical concepts," she said.
"Our findings show that children with specific language impairments have well-developed mathematical concepts, but may not know the conventional verbal symbols of arithmetic nor the verbal skills needed to solve mathematical problems."
Ms Levine said that some children with limited maths vocabularies would count on their fingers when solving problems. She said that this should not be discouraged, saying that it could even be argued that those who performed poorly and did not use their fingers should be encouraged to do so.
The researchers established that, as children approached the age of three, they began to develop non-verbal calculation. Over the following year the children quickly expanded their ability to understand the abstract relationship between numbers and sets of objects and events. By the age of four, after hearing a number of drum beats, most children could pick out a card with the same number of objects on it.

subset: commoncrawl


text: MWC – Apparently it's ok to have an HTC Re on the end of a selfie stick James Pearce March 4, 2015 Good morning readers, a bit of a random one for you here. This morning we were wedged on the train heading to the MWC venue and we stuck the HTC Re on the end of a selfie stick and filmed the train, the walk to the venue and the crowds. Sorry. http://youtu.be/afwgC1EadHw MWC - An afternoon with Kazam and their Windows Phones MWC - giffgaff to range the HTC One M9 too More from CoolsmartphoneHTC One M10 Rumours for MWC 2016What's in my bag (Leigh) – MWC 2015MWC – My top 3 things (James)Example footage from the new HTC RE cameraThree show off the HTC RE CameraHTC One M9 – Where to buy?MWC – HTC Event LiveRemember the HTC Re ? You can still get something like it..


text:
Time for a New Pilot (パイロット交代 ) is a cutscene in Resident Evil 6. It is played during Leon Chapter 5.
|This section is empty. You can help out the Resident Evil Wiki by inserting the appropriate content here.
Leon: "What the...!?"
"Damn it! I can't bring her up...! Come on!"
The original Japanese transcript for this file is not yet present. Please add it.


text: Borno State Governor, Kashim Shettima and the Chief of Army Staff, Tukur Buratai were part of the dignitaries at the Eid Fitr prayer which was concluded peacefully and successfully at the Ramat Square, in Maiduguri the state capital this morning. Unlike previous years, no bomb blast incident has been recorded in any of the prayer grounds in the state. The Eid prayer which was led by the Imam Idaini of Borno, Imam Asil Alsunusiyyu, also had in attendance other top government and military officials. More photos after the cut..


text:
617 Paseo Sereno - Homes for sale in el paso tx 79928
|Single Family, El Paso TX
|Price: $249,233.00
|Stories: 2
Beds: 4 & office/loft
Baths: 3 Full
|Sq. Ft.: 3258
|Lot Size: 6600
|Year Built: 2006
|Status: Available
|Contact Information
Home Owner
915-471-4266 or 915-471-0570
617 Paseo Sereno DR, El Paso, TX 79928
Short Description:
Almost 3,300 Sq. Ft. and Triple car garage. 3 Living areas including loft/office. 2 Dining areas. Plantation Shutters throughout. Heated POOL. French doors. Crown molding. 2 Fireplaces including a master with own sitting area. Built-ins. additional bonus room (play room or storage). Solar screens. Double and independent staircases. Professional landscaping and covered patio.
Contact Us About This Property
View Virtual Tour


text:
Who covered up, who didn't, and whose lawyers definitely had a say in the matter.
16 Photos of Paris Hilton and Kim Kardashian's Friendship That You Definitely Forgot About
Just as the legal system is theater, celebrity court appearances require costumes. Here, a lesson on how famous people dress to win—or not. Justice may be blind, but the public definitely isn't.More
What: An Italian widow vibes that says "I'm dead chic, but I'll still look remorseful for driving under the influence"
Why: "I'm dead chic, but I'll still look remorseful for driving under the influence"
Outcome: Charges dismissed in exchange for entering a voluntary alcohol education and rehabilitation program
What: A dark, notch-collar suit to testify in a copyright lawsuit alleging that he and Timbaland infringed on the rights to a sample used in "Big Pimpin'"
Why: Mogul
Outcome: Won the suit, in both senses of the phrase (I'll see myself out)
8 Literal Celebrity Fashion Statements


text: Business & EconomyHousemaid claims Kuwaiti torture Sri Lankan maid says employers drove 14 metal pins into her body after she asked for her wages. 16 Nov 2010 14:44 GMT | Business & Economy, Asia, Sri Lanka " /> " allowfullscreen="true"> A Sri Lankan maid has claimed she was tortured by her Kuwaiti employers, who allegedly jammed 14 metal pins into her arms and legs after she asked for her wages. The pins were removed from Lechchmi's body in a hospital in the Sri Lankan city of Kurunegala after two long operations. The allegation is the latest in a series of abuse claims by Asian workers employed in the Arabian Gulf region. In August, another Sri Lankan housemaid returned to the country with 24 nails driven into her body, saying her Saudi employers were responsible. Al Jazeera's Minelle Fernandez reports from Kurunegala.Source: Aljazeera


text:
APP OF THE DAY: Justin Smith's Realistic Summer Sports Simulator review (iPad / iPhone / iPod touch / Android)1/19 Pocket-lint
So it's almost over, and the Great Britain medal count is looking very healthy indeed. But enough about the annual drink as much as you can and then vomit into a shoe-athon, we're not doing too badly at the home soil Olympic Games either.
So, in order to eke as much as we can out of the current wave of London 2012 hysteria before everybody starts whinging about Olympic road lanes again, here's our current favourite OG-themed app. And it's a doozy...
Justin Smith's Realistic Summer Sports Simulator
- Format
- iPad (version tested), iPhone, iPod touch, Android
- Price
- 69p (iOS), 64p (Android)
- Where
- iTunes, Google Play
Justin Smith is the genius programmer behind Enviro-Bear, the classic App from 2010, which is either utterly brilliant and hilarious or tragic depending on which way you look at it - perhaps both, if we're being fair. Its cunning blend of 8-bit Atari VCS-style graphics and staggeringly simple gameplay had us all hooked back then.
Now he's turned his hand to something more topical, with his Realistic Summer Sports Simulator, which looks very much like button mashers of old but actually serves up something of a surprise.
Unlike a few of the Track & Field and Daley Thompson's Decathlon-inspired games on the app stores at the moment - including the official London 2012 effort - there are no buttons to mash on Smith's variety of Olympicsesque events. Instead, all the controls are touch-related and quite, quite bonkers.
There are 15 events in all, from 100M Dash to Equestrian, and each can be played either individually in practice mode or through a grueling multiple-event Games mode. It's worth opting for the latter no matter what because, first, the events are so mental in their approach, you needn't practice first; and second, the opening ceremony animation is a stroke of brilliance that's worth watching many times.
Then it's on to the events themselves. They often defy explanation, and get little, but most play in the same way. On just about every sport you have to pull along an athlete or their equipment using a springy rope, this will determine how fast, high or otherwise they travel. There's a power meter at the top that wears down the longer you use the rope/elastic and, er, that's about it.
Simple it may sound (and looks are basic) but there's plenty of gameplay in Justin Smith's Realistic Sports Simulator. To do well is extremely tough, requiring a mixture of timing, trial and error and sheer luck. You'll find yourself striving to do a bit better each time. And during the Games mode, there's no second chances.
For example, the Weight Lifting event needs you to spring the barred weights on to your 8-bit fellow, who's standing at the top of some wobbly steps. If he falls off, you lose. In fact, we haven't registered a single score on that particular sport in the game.
RSSS won't be for everyone, and some might find it funny initially and then tire of it. Thankfully though, Smith has recently taken it off a freemium in-app purchase model (where you had to buy most of the events as a separate pack) to a 69p all-in one (64p on Android). We can think of fart sound boards that cost the same and you'll get far, far more fun out of this.
- Skype's new look comes to desktops: What's different and how to get it
- Twitter is live-streaming the 2017 solar eclipse so anyone can see it
- Facebook: Here's how to make GIFs using the app's built-in camera
- Google Allo for web finally goes live: How to set it up and get started
- What is Amazon Instant Pickup, who can use it, and how does it work?
- What is Metromile pay-per-mile insurance and how does it work?
- Mewtwo comes to Pokemon Go via invite-only exclusive raid battles
- Uber will now let you tip your driver for good service
- How to use the Asos app to find the right clothes from photos
- What is Facebook Watch and which shows are available now?


text:
Rs. 295+ shipping charges
Rs. 295+ shipping charges
In 2015, the protagonist returns to his hometown Tirupattur in Tamil Nadu after 25 years. With the help of his classmate Vinoth, he tries to track down his other schoolmates for a silver jubilee reunion of the Don Bosco School they studied in.
He takes a trip down memory lane to the eighties. He recollects many interesting stories and incidents from his school life – the encounter with the panthers of Yelagiri Hills, the Naxalite bomb blast, Bosconians' mentorship, his fascination for the movies, meeting Rajinikanth, the cycle race with friends, and their love stories. The racy narrative unfolds several untold stories from the Sandal City where it all started. It also travels to Italy, Portugal, Kerala, Goa and Shillong.
The protagonist and his friends studied together, they stood by each other, and they overcame several hardships together. Even after several years, they continue to value their friendship. They also take immense pride in being a former Bosconian.
What happened to the protagonist's 60-odd classmates? Do they meet for their school's silver jubilee reunion? What had kept them apart for 25 years? Will the mystery be revealed?
Raj Sekar is an engineer who graduated from Anna University, Chennai. He did his MBA from the Bharathidasan Institute of Management, Trichy. Raj Sekar has worked as an investment banker and a brand manager. After a long stint with a bank, he turned an educational entrepreneur. He is a visiting professor in a college, and also coaches people for the civil services and bank exams. Apart from books, the author has a keen interest in movies and loves travelling. He has worked in different parts of the country. He is now based in Chennai.


text:
- Trending Now: More Trending:
- Svengali syzygy hegemon repugnant white nationalist, white supremacist
Definition of netizen
: an active participant in the online community of the Internet
Examples of netizen in a Sentence
the dismaying rudeness that so many netizens exhibit while online
Recent Examples of netizen from the Web
This week's headlines about HomeNet, the new study of online life by researchers at Carnegie Mellon University, confirmed every netizen's worst fears — at least their fears of more hyperbolic headlines about the Net.
These example sentences are selected automatically from various online news sources to reflect current usage of the word 'netizen.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.
Origin and Etymology of netizen
blend of net and citizen
First Known Use: 1984See Words from the same year
NETIZEN Defined for English Language Learners
Definition of netizen for English Language Learners
: a person who actively uses the Internet especially in a proper and responsible way
Learn More about netizen
Thesaurus: All synonyms and antonyms for netizen
Seen and Heard
What made you want to look up netizen? Please tell us where you read or heard it (including the quote, if possible).


text:
Meet the Stars of Tomorrow, Today!Raw. exciting. fast.
These are just some of the adjectives that are used to describe the FIBA U19 World Championship by those who regularly attend the event and inevitably fall in love with it.
Why? Because the play on offer is of the very top quality and yet independant from tactical rigidity, because the lockeroom is still free of oversized egoes and because the coverage and coloumn inches gain nothing from hyped up and exaggerated discourse, and because the attending basketball fans are fans and lovers of basketball first and foremost.
But as much as anything else, it is because you get to see the stars of tomorrow - the very best young talent in the world - before they become superstars and before the hype allows for them to be distracted from what matters most; their game.
The excitement felt by scouts, fans, coaches - even fellow players - in discovering the players who are on the brink of taking the world by storm, is always visible.
The history of this Championship, which will be played for the 10th time this summer, is star-studded with some of the biggest names in basketball, including the likes of Andrew Bogut, Linas Kleiza, Andrei Kirilenko, Pau Gasol, Vince Carter, Wang Zhizhi, Dejan Bodiroga, Steve Nash, Vlade Divac, Toni Kukoc and Arvydas Sabonis.
The potential and popularity of this event - first held in 1979 - made FIBA decide to move from a four-year cycle to staging the event every two years as of 2007. This will ensure that every generation of global basketball talent will have the chance to compete at the highest international level.
The 2011 FIBA World U19 Championship for Men will gather teams from 16 countries and five FIBA continental zones, featuring the world's best young players born in 1992 or after.
Europe will be represented by six teams – Lithuania, Russia, Latvia, Serbia, Croatia, Poland. The Americas zone will be represented by four teams – USA, Brazil, Canada, Argentina. Asia will have three teams – China, Korea and Chinese Taipei - while Africa will be represented by two teams – Egypt and Tunisia. Australia, representing the Oceania zone, complete the lineup.


text:
This website requires cookies to provide all of its features. For more information on what data is contained in the cookies, please see our Privacy Policy page. To accept cookies from this site, please click the Allow button below.
We use cookie for our website to work flawlessly. By using our website, you agree to our use of cookies. Please read our Privacy Policy for details.
Founded as the capital city of the USA in the 18th Century, Washington DC is unique in that it is not part of any of the American states.During the 1950s, DC also created some pretty unique rock 'n' roll, too, as made by the likes of Link Wray and his brothers.Capital rockers in every sense of the word.
Raucous Records is the longest establisted 1950s Rock 'n' Roll, Rockabilly and Psychobilly CD, DVD and vinyl specialist on the internet.A world of Rockabilly, Psychobilly, Surf, Swing and 1950s Rock 'n' Roll delivered to your door.
© Raucous Records 2017 All Rights Reserved


text:
Milodon SB Chevy Short Water Pum 16200 Mechanical Water Pump
Short High-Volume Iron Natural Small Block Chevrolet Pit Stop USA offers Milodon SB Chevy Short Water Pum 16200 at low everyday prices. Be sure to check out all of our products from Milodon including Milodon Small Block Chevy Water Pumps.Product Description: Water Pump, Mechanical, High Volume, 5/8" Shaft, 1-3/4" Inlet, Short Design, Steel, Small Block Chevy
- 806621162000
- Milodon
- Available
- Same Day Shipping!
- New
Shipping Information
- Item Requires Shipping
- 10.2 lbs.
- W8.4000" x H8.2000" x L10.7000"
- Ships from Michigan.
Customer Reviews
Total Reviews (0)
Write the First Review!
You must login to post a review.
May We Suggest
- The Company Difference
- We're the ExpertsWe help you find a way to win!
- Huge SelectionOver 90,000 products from the top brands in motorsports!
- Free Shipping On driver safety gear over $99!
- Low Everyday PricesGet the best values in racing!
- Have a question? Ask the Pros
- Email UsGet answers from the pros
- 1-866-722-3432


text:
Regular price
Is this product sold out ? please click here to check our other store SF store
Please refer to the Measurement Guide
We made a pair of slacks with 45R's denim fabric and named it "Surahiko". These slim fit pants carry non-denim like elegance. These pants are base distressed and adds natural wear and tear just like vintage denim. We are proud to offer these denim for denim lovers as well as those who don't really wear denim.
Cotton 100%
Made in Japan
This item is dyed with indigo-Please avoid wearing over or under white clothes.Color will stain run and stain.-Sweating or humidity may cause the color to run and stain other clothes. Please wash immediately when stained.-Please do not bleach-Please wash separately from other clothes.-Machine wash at 30c (86F) or gently hand wash.
*If you need more information for size, shipping, returns, please visit to our HELP page,or If you have any question about product, please send an email to us. click here.
Size Chart


text:
Management Marketing & PR Retail & FMCG jobs in Hertfordshire
Found 0 jobs
We do have the following jobs available for Retail & FMCG, Marketing & PR, Management
Showing 1 - 3 of 16
Senior Digital Communications Manager - Team Knowhow
We are currently recruiting for a Senior Digital Communications Manager to develop and execute the Services national and local marketing plans.
Category Manager (Multichannel Computing Development)
Positioned within the computing commercial team, you will be right in the centre of a fast paced, and exciting commercial team.
Campaign Planner
Would you love to own the end-to-end planning of integrated campaigns for this well known FMCG/retail client? You will lead the activation of all c...


text: Squirrel 2,856 Report post Posted October 25, 2013 wouldn't it be nice to free up 100mil in RB contracts to sign a WR, Hardy, and Cam.. if only we lived in a world where that were possible. Oh well. Be nice if we could restructure Johnsons contract. If I had my choice I would take Hardy over Johnson. 1 Share this post Link to post Share on other sites


text:
This flower ball has to be one of the most inexpensive and EASY pink and green Daisy baby shower craft ideas EVER! And I just had to share the pictures of the process just in case my silk flower ball instructions/tutorial fails to cover all of the details.
Here's everything that I used:
- a Styrofoam ball in whatever size you need. I used a 6 inch ball for this project
- 2 sheets of tissue paper per 6 inch styrofoam ball in a color that is similar to that of whatever kind of flowers that you plan to use
- A mini-hot glue gun. My regular sized one was just too much for me to handle on these little stems but you may be better at it than I am; you be the judge as to whether or not you can manage this without burning your fingers.
- Flowers of your choice. FWIW I started out with salmon pink Gerbera Daisies that I adored but I found that they didn't work. They were too wide and flat or something. The less expensive (read CHEAP!) Pink and green daisies look much nicer. It took more of them but they didn't cost nearly as much as the Gerbera daisies.
1: Remove a pile of silk flowers from their stems while the glue gun is heating up.
2. Smooth tissue paper over a portion of your ball. I didn't glue it or pin it in place but you can secure it with pins or a little glue if you need to. I just held it in place and then let the flowers do the work.
3. Dab a dot of hot glue on the stub of your blossom and quickly poke it through the tissue paper and into the ball.
4. Space the flowers so that their petals overlap each other slightly.
After the styrofoam ball is completely covered in flowers you can either display it "as is" on a pedestal or on top of a pillar of some sort or you can do what I did and attach a length of ribbon, decorate it with a big bow made from satin ribbon and hang it from shepherd's crooks along the sidewalk leading to the house where more of my pink and green Daisy baby shower craft ideas were on display. And yes, I will be uploading pictures of the pink and green baby shower invitations, decorations and dessert table very soon!


text:
"CCU are amazing"
About: Ipswich Hospital Ipswich Hospital Ipswich IP4 5PD
Posted by jai
My husband was admitted to CCU via A&E and was in a very serious condition. We have yet to discover the reasons for him being unwell. I can't praise the staff and environment highly enough- everyone from the consultants to the housekeeping staff .were wonderful. I felt he was safe and cared for and the support from the various team members was incredible. Not just providing the medical care he needed but were kind and supportive to myself, our son and our entire circle, because we don't have a traditional family. Even our dog was allowed a visit when my husband was feeling down. It was probably the most horrific 12 days of my life and they made it bearable and even manged to make me smile at a time when I didn't think that was possible. Quite possibly the most amazing department in the hospital and not given a slot in the drop box list. Shocking!
Response from Ipswich Hospital 3 years ago
Thank you for your very kind feedback. We will make sure it is shared with all members of the Critical Care Unit and Emergency Department teams.
- {{helpful}} of {{total()}} people think this response is helpful
- Was this response helpful? Yes | No
Thank you for your feedback.
See more responses from Ipswich Hospital


text:
AUSTRALIA: Even if Mitsubishi exits, Toyota won't leave - Toyota chairman
Toyota chairman Hiroshi Okuda has said that the company will continue to make cars in Australia. His comments were reported in The Australian Financial Review. Mr Okuda told the newspaper that the possible closure of Mitsubishi Motor Australia's (MMAL) manufacturing facility in Australia from 2005 onwards would cause difficulties for remaining carmakers in terms of higher costs. However, he reportedly said that Toyota would stay on anyway.
Get full access to all content, just $1 for 30 days
A Message From The Editor
just-auto gives its paid members access to the very best automotive market coverage.
And now there's just-auto plus, our premium membership that gives you exclusive component forecast data, company profiles and extended news coverage - just for premium members.
Today I can offer you 30 days access for $1 - and that includes just-auto plus.
Dave Leggett, editor of just-auto
* plus VAT if applicable
Only on


text:
The hectosecond (hs) is a unit of time in the International System of Units, defined as 102 seconds using the SI prefix system.
Hectosecond is equal to 1.6 minutes, so it can be used to specify periods of time that last for minutes. Light from the Sun takes five hectoseconds to reach Earth. There are 36 hectoseconds in an hour.


text:
Jul 31, 2017 | News
Click here for Event Details and Registration
Self-Monitoring for Housing is designed to assist Housing Departments and Housing Authorities in performing the required self-monitoring under NAHASDA. The course includes a basic overview of the requirements and in depth discussion of each self monitoring questionnaire issued by ONAP.
Information regarding only upcoming events, training's, and webinars subscribe below.
First Name *
Last Name *
Email (required) *


text:
What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
How do i align my forms properly in weebly?Asked by creativedistrict on June 30, 2015 at 06:33 AM
i've got quite a number of forms which has bad alignments.
how do i manually do it myself to correct the alignments?
JotForm Support
Hello creativedistrict,
I did check your web page where you have embedded your form and it seems to be aligned correctly. The issue is that it displays white at the bottom of the form. Is that the issue you are having?
Did you use the complete iFrame embed code including the script code in your weebly webpage? Here is the complete iFrame embed code of your form:

Alternatively, you can also try to use the following iFrame embed code as well:

Do get back to us if the issue persists.
Thank you!


text:
What does the Morula become?
A distinct inner and outer cell mass
A trilaminar embryo
The epiblast and hypoblast
The inner cell mass differentiates into which two structures?
The primitive streak indicates that gastrulation is occurring.
What is gastrulation?
The migration of epiblast cells to the primitive streak which then migrates down and displaces the hypoblast, forming a trilaminar embryo consisting, in descending order, of the ectoderm, mesoderm and endoderm.
The folding of the parietal and visceral layers of the lateral plate mesoderm in order to form the precursors to the bone and wall of the gut tube respectively.
The formation of the notochord from the notochordal plate in a cranial to caudal sequence.
The Ectoderm is destined to become what structures?
Tooth enamel
Nervous system
Gastrointestinal tract
Respiratory system
Cardiovascular system
The Mesoderm is destined to become which structures?
Connective tissue
Blood cells
The Endoderm is destined to become which structures?
Urinary system
The Notochord is important in signal secretion for nervous system development.
The primitive node is the "organiser" of the trilaminar embryo, and releases signalling molecules like NODAL, BMP4 and Noggin.
Neurulation is the formation of the neural tube. The embryonic plate elongates and folding creates a neural groove and neural plate. Somites, ridges either side of the groove form. Continued folding leads to a tube structure forming. The anterior and posterior neuropores then close, forming a neural tube.
The notochord release BMP that patterns the ventral side of the neural tube.
BMP is released which patterns the dorsal side of the neural tube.
Spina Bifida is caused by what?
Failure of the neural tube to close
Failure of neural crest cells to migrate
Failure of gastrulation
Mutations in SHH can lead to what?
Cyclopsia due to lack of bilateral symmetry
Inverted organ symmetry due to lack of wafting
The mesoderm differentiates into which layers?
Lateral plate - Parietal and Visceral layers
Folding of the parietal layer of the lateral plate mesoderm produces the precursor to the GI tract.
Somites differentiate into what three 'tomes'?
HOX genes are not responsible for coding for particular segments of body structures
Pharyngeal arches are located where?
Ectodermal side - ridges
Endodermal side - ridges
Endodermal side - pits
Ectodermal side - pits
There are 5 pharyngeal arches; 1st, 2nd, 3rd, 4th, 6th.
Neural crest cell migration is important in forming the ectodermal placodes. The crest cells aid in the formation of sensory ganglia of certain cranial nerves. Which cranial nerves are these and what conditions may result due to migration failure?
CN 5, 7, 9 and 10
CN 5, 7, 8 and 10
CN 1, 3, 10 and 12
CN 2, 4, 9 and 11
Digeorge syndrome
Robin syndrome
Down's Syndrome
Migrated neural crest cells can form 'cartilages' in the arches such as Meckel's cartilage. What is its function?
Precursor template for the mandible
Signal secretion for the developing embryo
Formation of the sensory ganglia in the arches
Which cranial nerve innervates the 1st pharyngeal arch?
Which cranial nerve innervates the 2nd pharyngeal arch?
Which cranial nerve innervates the 3rd pharyngeal arch?
Which cranial nerve innervates the 4th and 6th pharyngeal arches?
Which components of the skull are made from the 1st pharyngeal arch?
Zygomatic bone
Temporal bone
Hyoid bone
Styloid process
Which components of the skull are made from the 2nd pharyngeal arch?
Stylohyoid ligament
Cricoid cartilage
Which components of the skull are made from the 4th and 6th pharyngeal arches?
Thyroid cartilage
The medial and lateral nasal prominences join together to make the nose.
The fusion of the medial nasal prominences forms the secondary palate
The maxillary prominences fuse together to form the secondary palate
What condition(s) are caused by failure of the nasal, mandibular and maxillary prominences to fuse?
Cleft palate
Spina Bifida


text:
super sixes
Who doesn't love a list? These are our pick of the best events from beginner triathlons to the toughest 10k's.
Burnsall, known as one of Yorkshire's prettiest villages, is renowned throughout the world of sport for its Fell Race. As a spectacle, the scene has no equal. The Fell Race is the major event on race day. It is a comparatively recent event; according to tradition it began around 1870. A group of villagers are supposed to have discussed the idea in the Red Lion. The upshot of it was that Tom Weston, a well known local character, tested the course one moonlit night and ran it naked. The race then became an annual fixture.
Create your free profile to see what events your friends are doingsign up / log in
Some of the smaller (and not-so-small) brands making good stuff for events like this:
To find out more about how we can spread the word about your next event, drop us a line:


text:
quartzite crushing plant
Request for Quotation
You can get the price list and a ZME representative will contact you within one business day.
Quartz Sand Processing Plants Supplier Pakistan
Quartz silica sand washing machine for Processing Plant in Quartz crushing plant. The most silica sand is made up of broken down silica sand processing. The quartzite (quartz sand) is actually Impact crusherChat Online
Roller Drum Crusher For Quartzite Crushing
About roller drum crusher for quartzite crushing-related information:*beijing zhonghaiwei environment engineering co, ltd. cn zhonghaiwei is a manufacture of rubber expansionChat Online
Quartzite Mining Quartzite Mining Plant
Quartzite Mining-KAKATIYA OVERSEAS is suppliers of mining materials of Quartzite Mining.We are Exporters of Quartzite miningChat Online
quartz crushing machine india
Quartz Crusher, Quartz Crushing Plant, Quartz Crushing Machine Quartz Crushing Introduction to Quartzite Quartzite is also called quartz sand, silica quartz etc. QuartziteChat Online
quartzite crusher companies in india
Quartzite Crusher,Quartzite Crushing plant,Quartzite Crusher crushing & screening equipment companies in india; Quartzite Crusher,Quartzite crusher companies in india stone crusherChat Online
Quartzite Crusher Machine
Quartzite Crusher,Quartzite Crushing plant,Quartzite Crusher APPLICATION. Quartzite Crusher is an important cursher in the whole production Hydraulic Cone CrusherChat Online
quartzite crushing equipment
safety precautions for quartzite crushing plant from ZME. Shanghai ZME (safety precautions for quartzite crushing plant) is professional manufacturer, the main production stone crusherChat Online
quartz crushing plant sale
Quartz Crushing Plant,Quartz Crushing line,Quartz Crushing In quartz crushing plant, a primary jaw crusher is then used on the quartzite particles, Crushing line->Quartz Crushing equipment->Quartz CrushingChat Online
quartz crushing plant usa – ZME
quartz crushing plant usa Description : quartz stone crusher plant – 16 Aug 2013 a primary jaw crusher is then used on the quartzite particles, and they are transferred to a secondary jaw crusher (impact crusherChat Online
Crusher Plant For Quartz Crushing
Quartz crusher,crushing machine for quartz mining The raw quartzite production process should use quartz crusher. After the excvavtor and belt conveyor mining the quartzite from the quarry plant, the quartziteChat Online
Quartzite Crushing Machine From India
quartzite crushing plant project. quartzite crushing machine india. Quartzite Crusher,Quartzite Crushing plant,Quartzite Crusher Quartzite Crusher is an important cursher in the whole Hydraulic Cone . natural quartziteChat Online
safety precautions for quartzite crushing plant
Halogen lamp - Wikipedia, the free encyclopedia. A halogen lamp, also known as a tungsten halogen lamp or quartz iodine lamp, is an incandescent lamp that has aChat Online
grinding for quartzite rocks
grinding for quartzite rocks. Quartz Powder Equipment - stone crusher & grinding Quartz Powder Equipment, Quartz sand crushing plant is the major processing plant to handle with bulk quartziteChat Online
crushing plant safety
PLANT SAFETY The safety procedures mentioned here do not eliminate all safety hazards found in the area of crushing plants. CRUSHING PLANT "NOISE"Chat Online
Quartz Crusher,Quartz Grinding Plant,Ultrafine Quartz
Quartz Crusher Plant. Quartz crusher for sale in China,We supply quartz stone crusher,quartz sand crusher,quartz grinding machine. And the crushing and grindingChat Online
quartzite aggregate mining in india
quartzite crushing plant project - CGM Project Case. Quartzite Crusher Plant,Quartzite Mining and processing plant in india.quartzite using a meta-quartzite coarse aggregate from an off price of quartziteChat Online
sandstone, crushed basalt, and quartzite
sandstone, crushed basalt, and quartzite. Census Bureau And they are widely suitable for primary crushing of many kinds of mining and rock such as many kinds of ores, Beneficiation Plant; CrushingChat Online
Quartzite crusher in Malaysia
Quartzite crusherQuartzite crusher plant manufacturer & Supplier. crusher, or looking into Malaysia Quartzite crusher, you should know about ZME Machinery. It's the best mining crushingChat Online


text:
The Abia State Police Command rescued three children after busting a child trafficking syndicate in Umuahia, Punch reported.
The suspects were arrested after the police were alarmed by one of their victims.
The victim was initially lured by one of the men who had promised to marry her. She was taken to a beauty salon together with her two children and was left to do her hair.
Whilst she was busy with that one of the men arranged with a gang to take away the two children.
She contacted the police as soon as she realised that her children were missing.
Members of the gang were arrested and it was revealed that they were operating as part of a trafficking syndicate in the state.


text:
1.Paper towns by john green.
4.Quentin:Dynamic, self centered "what a treacherous thing to believe a person is more than a person" pg 282. he thinks of Margo as this great person waiting for him, but she wasn't waiting for anything, not even him.
b.Margo: Static, Open minded."We are digging graves for little Margo and Quentin."She always is looking at the bigger picture.
5.The theme for paper towns is nothing happens as you imagine it will. b)This is shown through Quentin search for Margo. c)"YOU WILL GO TO THE PAPER TOWNS AND YOU WILL NEVER COME BACK"
6. This is a complex story filled with teenage love, joy, and disappointment.Its a good story because it allows you to see a bigger picture on life, which isn't always pretty.


text:
Vine targets return
QPR striker Rowan Vine is looking forward to making his long-awaited return from injury.
By Chris Galea
Last Updated: 01/04/09 12:32pm
Queens Park Rangers striker Rowan Vine cannot wait to get back into the thick of things after being sidelined with a broken leg for just over a year.
The former Portsmouth forward has been out of action since sustaining the injury in a 0-0 draw at Ipswich last March.
He has been an unused substitute in Rangers' last two games, as he steps up his rehabilitation, but admits he is desperate to get back out on the pitch.
"It has been great to be back involved in the changing room and on the bench," Vine told skysports.com.
"I've been itching to get on the pitch, but the games have been very tight and I've not had a lot of football in the last year.
"The leg is feeling good and it is getting stronger game by game. I played a reserve game last week and played the full ninety minutes.
"There is another reserve game on next week, which will help increase my match fitness, but you never know whether you are really up to speed in terms of match fitness until you are thrown into the first-team arena once again.
"Tensions are obviously much higher than reserve games and the tempo is much quicker."
Vine is hoping to mark his return to the first-team fold at Loftus Road with a play-off place, and believes the Hoops are still capable of clinching a top-six finish in the Championship.
"I think we can still get into the play-offs, but it will be a tough ask after we hit some poor form a few weeks ago," he said.
"The recent wins have given us a huge boost, especially against two good sides in Swansea and Bristol City.
"I think anything is possible and we just need to keep the wins coming and we will go close. The next game, which is Crystal Palace at home, is another huge clash for us."


text: Catherine Bowne other resources ZAM · EQ2U · Census xml EverQuest II NPC Information Purpose Banker Race Human Zone Frostfang Sea (LU56) Location Inside Ravens' Roost ( -340, 173, -119 ) /waypoint -340, 173, -119 Retrieved from "http://eq2.wikia.com/wiki/Catherine_Bowne?oldid=654983" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: NPCs Frostfang Sea NPCs LU56 NPCs Banker (NPC Type) Frostfang Sea Banker NPCs Human NPC pages that need EQ2MAP uid Add category Cancel Save


text:
Hi all!
I have a question about how you all feel about sharing your recipes.
I'm just getting myself established as a baker in the community, and a woman I work with (but don't know well at all) asked for the recipe of a cupcake I brought to a work event recently.
What is your personal policy about sharing your recipes? I don't mean online in a forum setting like this, but within your own community, when sharing a recipe could potentially cut back business to you.
This may seem like a no-brainer to some of you, but I'm genuinely torn as to what to do. I don't want to offend anyone, but I'd like to keep my recipes private, as it is a business for me. Is that the general feeling you all have as well?
I'd love to hear thoughts on the topic!
no, if you're in business, you don't share recipes with someone you work with.
Different scenario, same subject -
Several years go, I held a holiday-time book party with a company that offered giftware. The party was a huge success with the people in my office building. One of the women asked me for the name of the sales rep, saying she wanted to hold one of these parties for her family. I foolishly gave it to her.
The following year, I passed out flyers in the building, letting folks know I was bringing the catalogs in soon. People waited with baited breath. Two weeks before my party, this same woman brings in the same catalogs, from the same sales rep! Needless to say, she sold a lot more stuff that year than I did.
Nope, do not give your recipes to anyone near you. They might start their own cupcake company.
I had this very dilemma last week. I respectfully declined giving her the recipe by saying thanks for your interest but I'm trying to build a a few cake flavors I could offer people who want my cakes. But I did tell her where I bought flavorings and said that I hope she understood.
She replied that she did.
I agree, and I'm a person who shares all kinds of recipes. When it comes to something of this nature where someone could use it to hurt your business, you just can't, and there is nothing wrong with explaining that to anyone.
Another thought to consider, and I'll give an example. I have a delicious cheesecake recipe that I share with anyone who wants it. Very easy to make, yet many people who have tried it tell me all the time it just doesn't come tasting the same as when I bake it. I tell you this because you could also run into a case of her using your recipe, not have it come out very good, and she is telling everyone how she used your recipe. You could have people staying away in droves because they don't like the recipe, without ever having tried it the way you bake it.
I'm just a regular ol' person - not in business or anything, but I would think twice before I handed out a recipe. Maybe that could be viewed as stingy, but there is competition in business and you want to make yourself as marketable and valuable as possible. Having special recipes, delicious goodies, etc. that no one else can produce can help with that.
Whe you turn your recipes in to the health department you write "trade secret" on them for a reason
I agree with everyone that you should not share your recipes. Your business is your own unique product that you have worked hard to develop, including your recipes. If anyone asks me, I just tell them that it is my policy not to share recipes, and they are very understanding. Good luck!
I'll be honest I am very picky on whom I share my recipes with. I don't mind sharing on a forum like this, but with people in my area or extended family members- no.
My cousin who is learning to bake asked for a couple of my recipes that I typically use for family get-togethers. I shared and then she started bringing them to the events.
I try to avoid repeats of this.
I'll be honest I am very picky on whom I share my recipes with. I don't mind sharing on a forum like this, but with people in my area or extended family members- no.
My cousin who is learning to bake asked for a couple of my recipes that I typically use for family get-togethers. I shared and then she started bringing them to the events.
I try to avoid repeats of this.
I hear ya'. I have had similar experiences. Even with my sister - I asked her not to share my recipes with other folks, but I've noticed that she's done it a few times and I have asked her about it. She'll give some excuse like, 'well, it was just so-and-so,' - that doesn't matter to me! I don't care who it is, I don't want them to have my recipes.
I like the idea of 'family recipes' that can be passed down. Sure, I know that some folks have similar or the same recipes in their cookbooks and I doubt I have reinvented the wheel or anything, but there is just something special about having your 'own' special dish or dessert among your friends and family.


text:
My non-combat resolution system works great, it does a wonderful job of keeping everyone at the table immersed in their characters and the fantasy world they are playing in. There is no faster way, however, to pull them out of that world than when weapons come out and combat ensues. Suddenly you've gone from deep role-play and vivid imagination to a series of bland dice rolls with lots of misses.
I'm currently running my low-level group through Keep On the Borderlands and they have just begun to explore the Caves of Chaos. The castellan told them of an Ogre harassing and killing his men along the roadway north and he needed someone to go deal with the problem by bringing back its head. While the group was buying supplies, the blacksmith's 16 year old apprentice, "Wort", a randomly rolled level 0 fighter-in-training (who happened to have extraordinary strength and constitution @ 18 & 18 respectively) decided to join up with them for the promise of adventure. So we have a Fey Elf, Demon Hunter (Cleric mod), and an iron-pumping teen fighter.
The group arrived at the caves in the evening and decided to setup camp in the grove just outside the Ogre's cave, which they just so happened to explore first the following morning. I've been trying hard to incorporate my non-combat system into combat as much as possible. I honestly don't ever want to fully remove combat rolling because I think you get into a place that no longer resembles D&D anymore and you've got to maintain some semblance of stat-based attack and defense. But, there is quite a bit of bending you can do to make things far more cinematic.
As soon as the Ogre was alerted to the group's entry into his cave, he came stomping out to see what was going on giving enough time for the group to realize that some huge "thing" was coming for them. Ogre's (and most of the early level creatures) are pretty stupid anyway compared to my PCs so it seems fair for the creature to forget any sort of intelligent ambush tactic. In many cases, I skip the surprise round because there is usually a party that is clearly being more careful and methodical than the other.
The elf immediately cast entangle causing the tree roots from above to grab hold of the Ogre's arms. The monster failed his saving throw, so he was unable to move his upper body for the rest of the round. He could still kick and hop though, so keeping your distance from his lower body became important. The demon hunter had found a Valerian dagger (dagger +1) during his last adventure (Valeria is an extinct kingdom of sea worshippers - think Atlantis) and wanting to use it badly, decided to climb the vines and swing onto the beasts shoulders. The demon hunter has very good dexterity, and since the Ogre couldn't move I arbitrarily assigned him a d100 70% chance of success, which he succeeded. In this position, the Ogre could not fight back against the attackers slashing at his neck and head.
The elf later did the exact same thing while the fighter apprentice slashed at the monsters knees with his longsword. The Ogre failed his save a second time and the fighter landed the killing blow with a d8 result of 7 + 3 (str bonus). The whole thing was very cinematic and took surprisingly few dice rolls to complete.
A few moments later, when the Ogre's goblin friends became alerted to what was going on in the room below them, a couple brave ones began climbing down a make-shift rope latter to attack the heroes. The players had the brilliant idea to have Wort shake the bottom of the ladder, throwing the creatures off and instantly killing them by getting dashed against the rocky cave walls. They then used their torch to burn the trapdoor, the smoke filling the goblin chamber above and causing the creatures to flee. All this without a single combat roll.
Visualizing the battlefield with all its nuances is key to running combat encounters this way. When you minimize the transition to and from combat, I think the suspension of disbelief can keep going strong in players' minds. A brilliant idea to kill or disable your enemy before the dice even start rolling I think is wholly in the spirit of classic D&D. The player characters were only level 2, 1 and 0, they really had no business taking on a level 4 Ogre along with 12 goblins at that stage of the game, but using their heads they were able to not only able to minimize the risk, but neutralize it entirely. Nobody lost a single hit point.
I used to run combat with bland dice rolls: "roll for initiative", "you missed, he missed, you hit, he missed, you hit, etc". I've learned along the way that it doesn't have to be like this at all, not even close.
My non-combat resolution system works great, it does a wonderful job of keeping everyone at the table immersed in their characters and the fantasy world they are playing in. There is no faster way, however, to pull them out of that world than when weapons come out and combat ensues. Suddenly you've gone from deep role-play and vivid imagination to a series of bland dice rolls with lots of misses.
Custom Classes
Posted by GaelicVigil
I reject codified custom classes in D&D, even for classic D&D (looking at you B/X Blackrazor). I just think that this mimics modern D&D did with all of its silly and limited skill, feat and class lists. I don't want a book to tell me who or what I should play, or what the right way is to play it. I want my imagination fueling my character. Having said that, I love players that think creatively when designing a class.
One of the biggest misconceptions of Basic Dungeons & Dragons concerns its class system. Most, including myself, will tell you that this was the biggest barrier to playing. The idea that you could only play a fighter, magic-user, cleric, or thief seemed incredibly limited. Race as class was an entirely different problem which I won't go over right now, but suffice it to say, it was hard to convince me that this game was anything but a seriously toned-down edition to the "real" D&D in modern iterations that gave you more options.
Obviously I now know better. I know now that "classes" in old-school D&D are really just archetypes or simple templates to keep your imagination in check. When making a character in Basic or 0E D&D, I always suggest to come up with a class that fits into one of the 4 archetypes listed at least as a basis to start from. Sometimes classes can blur the line a bit. For example, a "knight" class could be either a fighter or cleric depending on if you wanted a character that held to strong moral codes or not. A "swashbuckler" or "pirate" could be classify as a fighter or thief depending on whether you envisioned the character focused on fighting or cunning more often. Classic Conan in literature is probably more of a thief than a fighter, which I've gone over in a previous entry.
Thinking about classes in this way, you quickly realize that that classic D&D had far more flexibility than its modern cousins. Freed from stat lists and restrictive prestige classes, you can literally come up with anything you want to play as long as the DM allows it.
One of my players loves playing a Demon Hunter in Diablo 3. Now, good luck finding a B/X book with a Demon Hunter class, much less Diablo 3's version of it (not that I'd want that anyway). So without someone sitting down for hours statting out the perfect class to fit the game, how do I achieve this?
First of all, throw out the idea that a character's class needs to be completely defined and planned day 1. If a player wants to sit down with the basic Cleric template and let the game define and mold who his character is, great! There's nothing wrong with that at all. How many times have you said, "that class looks awesome!", then a few hours in you decide you want to be something different?
Alt-itis can be completely avoided in classic D&D because you don't have to put anything in stone during character creation. It may be during session 22 at level 3 that he gets a series of lucky rolls against some troglodytes and his character suddenly "remembers" that his sister was killed by a troglodyte when he was 11 and he has a racial bonus against them. Or perhaps the DM simply decides that this character has gained some insight into killing cave-dwelling monsters and will now have more success against them in the future.
Secondly, if someone does want to put some effort into defining his character early on, he can put as much effort into it as he wants. Don't worry about finding a perfect balance. Pick an archetype that fits most closely the vision of your dream class and then add 2 or 3 tweaks in the positive and 2 or 3 tweaks in the negative. For example, I designed the Demon Hunter class mentioned above to use any weapon, but shuns armor heavier than leather and is penalized for wearing it. He can turn evil planar creatures starting at level 1 along with undead, but his undead turning is weaker and fails more often than the standard cleric. Also, he prays to and gains power from a god like a normal cleric cannot heal wounds, only cause them.
That's a great start at level 1, and even if he wants more specializations in other things like a particular weapon like a crossbow, I will allow him to work toward it by using such a weapon or skill during his sessions of play. A player shouldn't get everything he wants at 1st level, he should set goals for how he wants his character to turn out. Goals are not always reached when he hits a certain level either, it may happen during an interesting session where he did something impressive, or arbitrarily after putting a little more effort into character back-story.
Negative things can and should happen as well based on poor choices, or simply because the DM and player agree on something negative balancing out something positive that occurs. This is a collaborative effort and neither the player or the referee should be able to hold all the cards when it comes to defining player class and character.
Posted by GaelicVigil
One of the biggest criticisms I've seen of D&D is its Vancian magic system. The concept of a magic-user that has to memorize spells and can only cast a limited amount per day until he has rested and studied his spell book again. There are many who attack it as being too limited and requiring adventurers to leave the "dungeon" too prematurely and often to rest and recover. D&D 4th edition did a lot to try and fix the "problem" by letting players fire off low level spells as often as they wanted. It seems many wanted things to be more "fair "so they could to be like a Jedi shooting off their powers left and right just like a fighter.
I would at least agree that, on paper, all of these old-school spell limitations sound pretty lame and limiting. And I can certainly sympathize with someone who would want to change it if they didn't understand the mindset of the system. First of all, trying to play with Vancian magic in a rules-heavy system like 3rd or 4th edition isn't going to work well. These are games designed for "encounters", a painfully derivative word that has come to mean, "interesting things that happen" (as if nothing else in the game is all that interesting and therefore undeserving of a title).
In an encounter-based game you're not thinking about the big picture. You're thinking about spaces to do "stuff" in, while the rest is sort of filler that needs getting out as quickly as possible. In classic D&D, avoiding monsters and these "encounters" was actually more important and rewarding. In classic D&D you're not supposed to run into the room with the dragon with swords drawn and blazing fireballs, you're supposed to find a way to get the treasure while avoiding the fight altogether. You're supposed to outwit the dragon, not necessarily kill the dragon. Afterall, the XP gained by killing the dragon was peanuts compared to the XP gained from a dragon's treasure hoard (where classic D&D rewarded XP based on gold piece value).
Killing mobs to get loot is so ingrained in peoples' minds these days from video games and superhero films, that it seems almost absurd to play an RPG of any kind where you're not doing just that. It's hard for non-classic players to really understand this concept even if you try to explain it to them. The level 1 magic user, with his one-use light spell becomes extremely important when a confrontation with a monster actually does happen. The key here, and a running theme throughout classic D&D, was player cunning and wit, not sword and spell, overcoming challenges. A classic player's character wasn't going to come out of a session alive if he didn't do or think of something pretty darn cool and out-of-the-box during the session. That is something that has been lost in modern D&D where brute force, and less thinking, has become the rule of the day.
However... :)
That's not to say you can't tinker with magic in classic D&D to make it more interesting. Other than a magic-user's wit and intelligence (which I'm not downplaying at all), he literally has nothing else to rely on during those early levels (where most characters live and die anyway). I want to make these classes more interesting and more dynamic to play. A house rule that I have been using in my latest campaign is for my players, an Elf and a Cleric, to be able to use their magic as a sort of fountain of power, rather than a one-shot blast.
The original house-rule I borrowed from someone else is to allow players to cast very minor versions of their spells for free. So a magic-user could light his pipe or even start fire with his Fireball spell. With Light, you could use it to send some "morse-code" styled signals. Etc.
My version of this house rule actually takes it a little further. I keep a mental note of how much of a spell is being used throughout the day and to what degree. Again, in the fireball example above, a player could decide to use his ability to "spark" some kindling perhaps 5-10 times a day, or instantly create a roaring fire for 1/2 the cost of a normal fireball. It will require some creativity to determine just what you could do in a minor fashion for some of the spells. I still haven't figured out how floating disc could be useful. But a clever player could probably surprise me in the right situation.
In any case, the player is spending his magic energy pool in creative ways that count toward his spell limit that day. I don't keep any hard rules for this, I just make a note in my head of how much he's used of his spell. Yeah, I know this is like a "mana" pool for each spell use, and some grognards may think that's heresy, but I personally believe this hybrid system fits even better with Appendix N than what we got.
My main source for this comes from Gandalf, but you could find a lot of other examples as well in D&D-inspired literature. Either because he likes being clever and subtle, or the physical drain is too much, very rarely do you see his full magical power being used. Instead, he's constantly being creative with his magic to scare or fool the bad guys. You can also see his weariness after using his magic, or in greater degree (eg holding the door shut from the Balrog and his encounter with the witch king) I like this approach more than the "bazooka wizard", that nukes everything in sight. And I feel it has a lot of old-school flavor. Magic-users can be far more versatile and creative and will never feel like they are useless after their spells have been used up after five minutes of adventuring.
Players will need to weigh the pros and cons to using their magic in one big shot, or in a lot of minor ways. Using your magic to start the fire this morning means that you're going to be in a world of hurt when you face a group of zombies later that day. Overall, though, this gives magic users far more options and freedom, something I think defines classic Dungeons and Dragons.
Favorite MMORPG
Posted by GaelicVigil
I haven't posted much about Massively Multiplayer Online Games since I started posting here because, in most cases lately, I haven't been much of a fan. Without going into a giant history of the genre, they have become synonymous with grinding, or endless loot and experience farming for no other purpose than showing your uber "toon" off to others. This isn't to say I don't play any of them. I've played my fair share, including World of Warcraft, Guild Wars 1 & 2, and some other lesser-knowns. I don't consider myself super hardcore or anything like that, but I've been around the block a few times and for a while I enjoyed them. Most of my stints have been short-lived, my enthusiasm petering out after a few weeks. After a time they all seem to share the same faults that I had come to dislike.
But it wasn't always this way, there was a time when MMORPGs were new, even during the earliest MUD days, when online games aimed for real worlds and not just loot-grinding theme-parks. These are the games I think a lot of RPG fans dreamed about when the internet first became popular in the early 90s. One of the biggest games that launched in the late 90s that attempted (at least at first) to reach these dreams was EverQuest. While this eventually became the model for most modern game MMO game design, many people I think forget how many things modern games lost in translation to the original template.
Things like dropped loot on death which required "corpse-runs" meant that if you were high enough level and you lost your equipment in some deep dungeon, you may never see it again. Other interesting mechanics included the requirement for players to literally spend hours sitting and reading spell books to memorize them. The game also lacked many things modern MMOs take for granted, like quest markers, and even an in-game map!
I love EverQuest for everything it did and still does (although the game has changed a lot since its beginnings). If you want the real EQ experience, I recommend checking out Project 1999, an emulator that mimics the game as it was before Sony Online Entertainment screwed it up after the Velious expansion.
Anyway, my purpose of this post isn't really to talk about EverQuest, but its sequel, EverQuest 2 which I'll get to in a moment.. What I'm really trying to say in this post is that I think I've come full circle a little bit. During those early-days, including MUDs, I could tolerate the repetitiveness of these games just fine. After several years, I went through several years where I could not tolerate anything but "sandbox" worlds. Now, an MMO has changed my mind a bit.
For a long time I avoided EQ2 because I had heard that it shared basically nothing with its predecesser. "It's another WoW themepark clone", I was told (even though EQ2 actually predates WoW) and I wrote it off. This was during the time I was playing Guild Wars 2 and its shiny new event system which I will also get to in a minute. But it's interesting what can happen to your opinion when you're presented with something that completely upends your preconceived notions of it.
EverQuest 2 is a theme-park* MMO. And I apologize for throwing around terms that may be unfamiliar to some. The term, "theme-park" refers to a type of MMO that revolves around following and solving quest hubs that lead you onto another quest hub, and on and on. Basically it reminds you of a theme park because you are going to and from static attractions. There is no real, "living" world or anything like that of a "sandbox" MMO. In other words, they're not even trying to make things plausible or realistic. In general, in my opinion, most of the time this is "can" be a bad thing.
I add the caveat because EQ2 is perhaps the single exception to any MMO I've played where this actually works. Why does it work? It's certainly not because the game does any one thing better than any other game. In other words, there is not one single mechanic that this game hits out of the park. You can pick any one thing and probably find it done better or equally well elsewhere. But, you see, EQ2 does so many things pretty darn well that makes it shine. While most games boast one or two "revolutionary" mechanics to advertise themselves, they are lacking in other departments.
I want to talk about big. There are a lot of "big" video games out there. They are usually measured in a lot of ways; geographical world size, number of hours, number of NPCs, etc. But usually when we talk about a "big" game, we are measuring breadth, not depth. I like using the Elder Scrolls games as a good example. These are enormous games. Giant worlds, tons of stuff to find, lots and lots of dungeons to explore, loads of quests and so on. But, when you think about it, most of these mechanics are only skin deep. Most dungeons, NPCs, and loot start to feel rather similar after a while. There are a lot of them, but they don't really provide much depth.
A very good way to understand game depth is the total number of unique assets a game uses. Assets include unique graphics, sounds, music, and data. A lot of people will say Daggerfall is the biggest game ever, but only if we're defining its breadth. It's actually a really shallow game in terms of breadth. You will probably see nearly every game asset within the first couple hours of playing it since all dungeons and towns use the same textures, models and data. Daggerfall is one of the largest games in terms of breadth, but one of the smaller games in terms of depth.
Now the biggest games of all require both a lot of breadth and a lot of depth. I believe MMORPGs qualify as the biggest games since they have both in spades. It's difficult for non-MMOs to compete because once their development cycle is finished, other than perhaps a couple expansions, the game is complete. The only way they can compete is by using a lot of procedural and random generation. But that's not depth. In the table-top world, P&P games probably have a lot of breadth as well since a GM is required to continue facilitating fresh content whenever a game is played.
And the biggest video game of them all in terms of breadth and depth? I think EverQuest 2 may very well be the king. And this is precisely the reason why the theme-park model works here: content. EQ2, with 10 expansions and multiple, deep, systems, is overflowing with stuff to do. The best theme-parks are those with lots of attractions, and EQ2 doesn't disappoint. It's really quite ironic because since EQ2 has so much stuff in it, so many fresh places to see and experience, I feel like overtime this theme-park has actually become much more of a sandbox.
I've spent 30 hours in this game and haven't even completed the first zone. With hundreds and hundreds of zones, you can see how big this game is. And that's not even touching the myriad of sub-systems the game has to offer. I just want to go over some of these systems.
I want to spend a minute talking about the bread-and-butter system of pretty much every modern MMO: the quests. EQ2 follows the general follow-the-arrow-above-their-head mechanic of other games in the genre, but with some important caveats. First of all, there are a gazillion of them. Unlike its predecessor which oddly had a lack of quests, EQ2 makes good on its name and just overwhelms you with quests to complete. This is actually very important because it means that you will spend barely any time at all grinding (or just killing stuff with no reason than to gain xp and loot). The game gives you so many goals to achieve that every bit of your experience can be had with a purpose. I can't explain how much difference that really makes in a game like this, but it really helps.
Secondly, the adventuring quality of EQ2 is helped by the fact that many of its quests have permanent world effects. I was shocked to find out that after killing some monsters in a quest actually meant that the monsters were permanently gone. This means that your affect on the world actually has some permanence to it, and that is a really nice touch. Coming back to a completed area will stay completed forever. The only other game that does something like this is Guild Wars 2 in their dynamic questing system, but oddly enough, I found EQ2's system to work better since the changes you make actually stay persistent.
GW2 uses a looping system for all dynamic quests. So, for example, if the centaurs are attacking a camp you're supposed to kill them off which, eventually, saves the camp. When you're done with this, the camp stays saved only for a short time. When you come back the next day, you find the centaurs attacking the camp again because the quest has reset itself. At first this seems cool, but you eventually realize that the whole thing is a gimmick. Just a way to hide the static world making you feel like you really have no impact at all. In EQ2, things stay changed forever. And I like that far more. What's amazing is that hardly anyone realizes that a better realized system for permanent changes already exists in EQ2 which has been drowned out by the hype machine in GW2 PR department.
Many MMOs boast crafting systems, and although EQ2's crafting system is a pretty fun sort of mini-game, I've seen something similar before in games like Vanguard. But what makes crafting really cool in EQ2 is the sheer amount of stuff you can make, and how early on in the game you can do it. This isn't something reserved for high level characters, this system runs on its very own level up system. By gathering and crafting, you gain unique crafting levels, distinct from adventuring levels. You can literally play the entire game as a pure-crafter and not kill a single monster. This is really cool and makes the system feel like it has a big part of the game and not something just tacked on.
Housing, unlike other games, plays a very big role in EQ2. Again, not something for high-levels. You can start buying homes very early on. They come in a million varieties, from a two-room apartment, to a giant castle with outdoor areas and multiple levels. Furniture can be gained from quests, loot, and from crafting. Housing is a thing of beauty in EQ2. Again, you could spend your entire game crafting and decorating your house.
Dungeon Builder
Like the housing system, there is an equally deep and interesting dungeon building system that you can create yourself and let others enter. One interesting thing here is how you can obtain "monsters" in the same way you can find drops for housing. This provides an interesting way to build up your dungeon inventory rather than just getting everything at once.
Character Customizatoin
If I'm not mistaken, I think EQ2 has the most number of race/class combinations of any modern game. Besides regular adventuring and crafting experience, the game has Alternate Advancement, points you earn like XP that you can put into very specific traits to further specialize your class. So between all the options available to me, I'm playing a Human, Rogue, Swashbuckler, Fencer. The combat system can be extremely deep because of this. Chained, heroic attacks, and different kinds of buffs and positional abilities make the game easy to learn but extremely complex to perfect. Not only are there tons of combat abilities but, lots of non-combat skills, upgrades, heroics, dragon and more that you can obtain. The number of options is dizzying.
There is an appearance tab where you can replace any item you are using with another for flavor. This is awesome since it means I never have to be locked in with what I'm using for others to see me with.
You have loads of mounts that vary from standard ground-based rides to leapers, gliders, and full fliers. You also can get pets, and lots of interesting appearance equipment. And like everything else, this stuff is available very early on, not just for the ultra-rich or high level characters.
The loot is extremely varied. Besides weapons, armor and other trinkets of varying color you can equip with, you have the aforementioned furniture and monster pickups as well as collectible "shinies" (that I've only seen in Rift and Xenoblade Chronicles). You also have Lore and Legend pickups which start a quest to learn more about monsters which can give you a special monster specific ability. You can also find other quest-starting items which can send you off to a distant continent for a completely separate quest chain.
One nice touch is the inclusion of books. A game gets a +1 in my mind when there is background lore to be read. EQ2 includes lots and lots of books, of which you can build a library around in your home or guild hall. Also, there are writable books where you can record a journal. Very nice touch.
You have guilds and grouping like other games, but a really interesting mechanic is mentoring. There is so much content in this game and it is practically impossible to see everything, much less experience it while at a level to make it interesting. With mentoring, you can group with someone 50 levels lower than yourself and all of your power and equipment will scale down to your mentor. Not only does this make low level content still viable, but you still get experience for doing it. You can do this in a group or even lower your own level and do the content solo.
This may not be as important for some people, but as I've written about before, theme is very important to me. A good, engaging world can make a bad game descent, and and average game great for me. Theme includes everything rolled together: art, music, design, lore, and story. I love all of it in the EverQuest universe. The art is classic fantasy styled. No, puffy marshmallow heroes here. Monsters and heroes are modeled after 1980s fantasy art. The game has possibly the best theme song of any MMO and a crap load of songs and sounds for every zone. The world is designed to be high-fantasy swords & sorcery in a classic sense. What makes the lore great is that it's subtle. You find bits and pieces in books and quests throughout the world, forcing you to put the story together yourself.
I like the fact that EQ doesn't require me to suspend my disbelief as much as other games. Lord of the Rings Online, Age of Conan, Star Wars, and other IP-based MMOs are a hard pill to swallow because they stray so far from the source material. Why are there all of these random hobbits running all over Moria in LotRO? In EQ, I can love the world as a crazy, everything and the kitchen-sink, generic fantasy universe without worrying about things staying all consistent. But at the same time, the game is strictly S&S fantasy. There's fairies, dragons, goblins, trolls, gnomes, and more....and thankfully no gonzo lazer guns or space ships mixed in.
With all of these features, it becomes very simple to role-play as well. The other day while doing some questing in-game, I was surprised to find a wolf following me around wherever I went. This was a person playing a Warden class who had shape-shifted. This sparked a tremendous RP opportunity to have a player-run pet.
The community is older than most, because many players grew up on the original game way back in 1999. These players are far more mature and dis-positioned to role-play than other MMOs. There's always an interesting interaction just waiting around the next corner.
I could keep going, but the bottom line is that the game is just chocked-full of content to do. That's why the theme-park model works for this game and why it may very well be the biggest game I've played. Big in both breadth AND depth. There is never a dull moment in the game, never a reason to have to grind, and never a reason to feel like you're led by the nose. For that reason, this is my favorite MMORPG at least in the standard AAA sense.
The best part is that the game is free to play. Other than the dungeon maker (which costs $15), everything else is completely free. Very little is locked behind pay content. And SOE has a reputation for making past expansions free when they release a new one. So if you like something you have to pay for now, just wait a year or so and you will probably see it become available. But with the amount of stuff to do for free already, it's unlikely you'll ever be looking for more anyway.
Come and check it out. I play on the Antonia Bayle (RP) server as Jemmajune.
What I'm Playing
Classic CRPGs
Tenebrous Campaign
About Me
- GaelicVigil


text: Staygold, Spank Rock, Damien Adore - Backseat (Stay Ali Remix) by Stay Ali published on 2010-11-15T22:46:42Z This is an official remix we did for Staygold (feat. Spank Rock and Damien Adore (Salem Al Fakir)). The tune was a hit in early spring 2010 (I think it was?), and we had a good time remixing it. Our remix should've been released on iTunes, Spotify etc this summer but the release is delayed. Hopefully it will be released sometime soon, anyway. While waiting for the release, you'll just have to listen to it here on soundcloud :) Enjoy! Comment by NICKY DISKO look here i am like.. probly a year later. CAN I PLEASE GET THIS TRACK? ILL BUY IT. IM OBSESSED. 2013/02/07 22:27:11 +0000 Comment by drypotatochips favorite one =D 2011/12/23 23:44:44 +0000 Comment by neaumusic fuckyesmusic.com!! dude i fucking LOVE YOU. SERIOUSLY. WHERE HAVE YOU BEEN. all hidden away on soundcloud and shit. not cool 2011/12/23 04:20:39 +0000 Comment by NICKY DISKO aghghghhh where can i download 2011/12/18 07:03:09 +0000 Comment by Stay Ali @spookycheddar: it was supposed to be released like 1.5 years ago, still waiting for Staygold to release their album :( 2011/11/30 14:11:04 +0000 Comment by COP FONT Please release this, I'd like to buy it! 2011/11/21 20:00:37 +0000 Comment by NICKY DISKO STAY ALI. im still jamming this song bro!? where the F can i download this... 2011/07/25 23:39:23 +0000 Comment by NICKY DISKO i swear you guys dont even know how this song cranks.. this needs to be in some movie 2011/01/27 20:37:48 +0000 Comment by NICKY DISKO yo, ive listened to this song like 20 times now. i hope my sound gets on your guys level soon 2011/01/16 01:53:25 +0000 Comment by Stay Ali @auxiliaryinput: it is in fact a bass sample from the original song that we put a lot of effects on. So you are right, thats why it gets shorter when the pitch is higher :) 2010/12/08 14:12:32 +0000 Comment by CapsAdmin I love how the bass behaves ike a short bass sample when going higher up 2010/12/08 10:24:12 +0000 Comment by stadtkindbln Really good stuff. I like this remix more than the orginal song! 2010/12/06 07:50:02 +0000 Comment by shnny This is fantastic. 2010/11/28 22:22:36 +0000 Comment by jameseduardo Stay Ali ? Wonderfull 2010/11/22 22:47:56 +0000 Comment by * Pedro Mónica * COOL 2010/11/22 11:40:01 +0000 Comment by ThiB chill remix! loving it! 2010/11/17 20:01:13 +0000 Comment by StardonE i like it! 2010/11/17 00:07:05 +0000 Comment by WeAre| <3 2010/11/16 08:02:55 +0000 Comment by FuckOurOrdinaryLives nice! 2010/11/16 00:35:28 +0000 Comment by Owl Vision riktigt smooth :) 2010/11/16 00:30:57 +0000


text:
- Product Details
Start placing our Personalised Traditional Christmas Stickers around your home and you will soon get into the swing of the festive season.
These beautiful self-adhesive decorations are all you need to transform your house into a winter wonderland, while keeping an eye on style at the same time.
All of the gorgeous Christmas stickers in this set use our hand selected festive red to create a truly traditional festive feel. With images of Christmas trees, snowflakes and candy canes included, all you have to decide is where to put them.
For the largest images, opt for the A3 sized sheet. Or for something a little more discrete, the A4 sized sheet will be perfect for your room.
If ever there was a time to transform your home it's in the run up to Christmas, so make sure you spread a little magic of your own.
A3 Sticker Size: Sticker sizes are bigger than A4.
A4 Sticker Size: Sticker size vary.
- Delivery & Returns
We are aware of how important it is for you to receive your gifts in time. Therefore, once you place your order we will process straight away and dispatch as soon as they are ready to go. We usually dispatch all items within 24-48 hours, however, this may be a little longer during special occasions such as Mother's Day, Father's Day, Christmas, etc. If multiple items ordered, we may dispatch items separately or all together, depending on the process.
*2nd CLASS ROYAL MAIL
Sent via 2nd Class Mail for only £3.99.
*1st CLASS ROYAL MAIL
Sent via 1st Class Mail for only £4.99.
Sent via Royal Mail Tracked for only £5.99.
Orders received by 2pm, sent via next working day courier tracked service for only £7.99.
Orders received by 2pm, sent via Royal Guaranteed Saturday Delivery for only £9.99.
The cost for delivery to European countries is calculated based on the destination. Please allow approx. 2-5 working days from dispatch, however, this is not guaranteed.
Below areas will incur a remote area surcharge - £30
*Italy: Livigno & Trepalle, San Marino, Vatican City
*Spain: Ceuta, Melilla
*Finland: Aland Islands
*Free delivery excludes items that are on offer or discounted from the original price and sent via 2nd Class Royal Mail, only UK.
*2nd Class Royal Mail - Royal Mail aim to deliver within two to three days, however, this is not guaranteed by Royal Mail, only UK.
*1st Class Royal Mail - Royal Mail aim to deliver your order one to two days, however, this is not guaranteed by Royal Mail, only UK.
*Premium Tracked - Royal Mail aim to deliver your order the next day, however, this is not guaranteed by Royal Mail, only UK.
*Next Working Day - All Orders placed before 2pm will be delivered next working day (Excludes Northern Ireland, Overseas UK addresses, and Parts of Scotland).
*Saturday Delivery - All Orders placed before 2pm will be delivered Saturday (Excludes Northern Ireland, Overseas UK addresses, and Parts of Scotland).
*All our items require production time and this is stated on individual product pages.
We're sure that you will be satisfied with your purchase and we also understand that sometimes you may want to return. We keep this process simple! Just contact us if you wish to return goods. Please note: personalised, made-to-order and perishable items are non-refundable.
- Ask a Question
Ask a Question
Question about: Personalised Traditional Christmas StickersPlease do not include or disclose any sensitive personal information, password or credit card information in your message. Your personal security is extremely important to us.
Wednesday, 9 December 2015 (by Kate)hi,
how do i personalise these stickers?
Also, i want to stick these on my window but can the design be seen from outside or inside only?
Show more products in Personalised Stickers


text:
Methylotrophic methanogenic Thermoplasmata implicated in reduced methane emissions from bovine rumen - in: GGAA2013 Conference Proceedings
- Authors:
- Abstract:
- Introduction Enteric methane (CH4) production by ruminants is a major source of anthropogenic CH4 emissions. The CH4 is derived from complex anaerobic degradation of plant biomass by the rumen microbiota, the terminal group being methanogenic archaea. The methanogens have been targets of a plethora of methane mitigation strategies, often aiming at reducing concentrations of H2; the major energy source of most rumen methanogens known to date. However, not all rumen archaea are yet physiologically characterized. Using a metatranscriptomic approach the present study investigated the effect of dietary manipulation, aiming at reducing enteric CH2 production, on the active rumen microbiota. Materials and methods Four rumen-fistulated Holstein dairy cows were fed a control diet (total fat: 3.5% DM) and a rapeseed oil (RSO)-supplemented diet (total fat: 6.5% DM), in a conventional 4×2 cross-over design (three weeks per feeding period). One cow was excluded from the full experiment due to health considerations not related to the diets. Methane emission from the cows was quantified at the end of each feeding period in transparent polycarbonate chambers (Hellwing et al., 2012). Concomitantly, rumen fluid was sampled from the top and bottom part of the frontal, mid and distal section of the rumen (25 ml per section), pooled, physically disrupted to release microorganisms from organic matter and filtered (pore size: 0.5 mm). Total nucleic acids were extracted using a standard phenol-chloroform bead-beating procedure. DNA was removed and double-stranded complementary DNA (ds-cDNA) was synthetized from purified RNA. The ds-cDNA was sequenced using the Illumina HiSeq2000 system (≈160bp; paired-end sequenced from 2×100bp read lengths). Concatenated small subunit (SSU) rRNA reads were analyzed according to Urich et al. (2008) and putative messenger RNA (mRNA)-related reads were analyzed by Meta-Genome Rapid Annotation using Subsystems Technology, v. 3.1.2. (MG-RAST) with subsystem-based annotation based on the SEED database and with MEGAN4 analysis of BlastX searches against the Genbank Refseq protein database (e-value cut-off 1e-5). Results RSO significantly reduced CH4 emission from the cows, resulting in a 6.2% lower CH4-to-CO2 emission ratio (P<0.05). Illumina deep sequencing resulted in ~10-12 Million high-quality reads per sample, of which putative mRNAs comprised between 380,000 and 485,000 reads. Analysis of SSU rRNA reads revealed that archaea were significantly decreased upon RSO supplementation, whereas bacterial and eukaryotic taxa were basically unaffected. The decrease of archaea could be assigned to a novel group of methanogens distantly related to Thermoplasmata ("Rumen Cluster C", RCC) (Fig. 1A). In contrast to well-known hydrogenotrophic methanogens (Fig. 1B and D), the novel RCC methanogens decreased in abundance and activity upon RSO amendment, as illustrated by the 16S rRNA and methyl-coenzyme M reductase subunit α (mcrA) transcript levels (Fig. 1A and C). mRNAs of enzymes involved in methanogenesis from methylamines (MA), only distantly related to known variants from methanogens, were among the most abundant archaeal transcripts. These transcripts, decreased in abundance upon RSO amendment (Fig. 1E), concurrently with 16S rRNA and mcrA of RCC, making the RCC methanogens the likely origin of these mRNAs. Conclusions Metatranscriptomic analysis enabled in situ characterization of a novel, yet uncultured group of rumen methanogens. These RCC methanogens are putative methylotrophic archaea, and the second order of methanogens able to utilize methylamines. The RCC methanogens may potentially be a key target for strategies to mitigate CH4 emissions from ruminant livestock. Acknowledgements This project was funded by the Ministry for Food, Agriculture and Fisheries, the Faculty of Science and Technology, Aarhus University, Denmark and the Austrian Federal Ministry of Science and Research (GEN-AU III InflammoBiota). References Hellwing, A.L.F., Lund, P., Weisbjerg, M.R., Brask, M., and Hvelplund, T. 2012. Journal of Dairy Science. 95, 6077-6085. Poulsen, M., Schwab, C., Jensen, B.B., Engberg, R.M., Spang, A., Canibe, N., Højberg, O., Milinovich, G., Fragner, L., Schleper, C., Weckwerth, W., Lund, P., Schramm, A., and Urich, T. 2013. Nature Communications. 4. Urich, T., Lanzén, A., Qi, J., Huson, D.H., Schleper, C., and Schuster, S.C. 2008. PLoS ONE. 3.
- Type:
- Conference abstract
- Language:
- English
- Main Research Area:
- Science/technology
- Review type:
- Undetermined
- Conference:
- Greenhouse Gases and Animal Agriculture Conference 2013
- Submission year:
- 2013
- Scientific Level:
- Scientific
- 2185932918


text:
United Selects Momentum Worldwide to Lead Global Marketing
United Airlines today announced the selection of Momentum Worldwide as the sponsorship marketing agency partner for the company's consolidated global sponsorship portfolio. Momentum will join New York-based mcgarrybowen, the lead creative agency, and New York-based Horizon Media Inc., the media investment agency, to execute the airline's advertising and brand building efforts.
After an extensive search which began in the spring, United identified Momentum as the strategic planning and activation sponsorship marketing partner that will help manage its portfolio of more than 25 sports and entertainment properties nationally and in its hub markets.
© 2017 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.


text:
KOCHI: A friend of C A student Mishel, who died under mysterious circumstances, has revealed to the Crime Branch that Cronin, who is under arrest in this connection, used to physically and mentally harass her.
The friend said he used to call her to place near the hostel and harass her. This revelation has strengthened the police' suspicion that Cronin used to often fight with Mishel and she committed suicide due to his sadistic behaviour.
Cronin didn't like Mishel getting close to anyone else. He wanted her to be completely subservient.
A friend of Mishel, who is doing higher studies in Chennai had already quoted Mishel to have said that she was finding it difficult to get along with Cronin.
Mishel also wanted to join her Chennai friend for studies but Cronin was against this.
In between this, Cronin used to quarrel with Mishel over her friendship with another person called Christy. He had called Christy and warned him against talking to Mishel.
The friend also told the investigators that Christy even beat Mishel once.


text:
White Hoodies & Sweatshirts for Girls(1 Product)
Sort byMost popular first
- Your choice:
- Girls
- white
- Reset selection
Wilson Tennis Apparel
Tennis PO Hoody Girls - White, Red
40,00 €24,90 €Available sizes:
* All prices incl. VAT
The crossed out prices are the RRP.
The crossed out prices are the RRP.


text:
Need a Thyroid Test in Media, PA? Simply order online 24/7 and get a fast, affordable Thyroid Test at a lab near you (Find More Locations):
What is a Thyroid Test?
A Thyroid Test consists of lab tests to check the thyroid. People in Media, PA get a Thyroid Test for general screening or at the request of a medical provider.
How much does a Thyroid Test cost?
Our Thyroid Test prices include the doctor's order that you need to get tested in Media, PA, all lab fees and taxes, and a pdf copy of your results. For current prices, please CLICK HERE.
What does a Thyroid Test lab report look like?
For a popular Thyroid Test sample report, please CLICK HERE.
We are delighted to offer the Thyroid Test in Media, PA.
Thyroid Test in other cities near Media, PA:Aston | Brookhaven | Broomall | Chester | Concordville | Edgemont | Glen Riddle Lima | Lenni | Newtown Square | Springfield | Swarthmore | Wallingford | Wayne | Woodlyn