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What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
JotForm Support
We can definitely do that. Please let us know when you are done with the basic configuration of your form. Please make sure that you provide the URL of your form too.
Please contact us whenever you need assistance. We will be glad to be helping you.


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Win a Flyaway Trip + Two Nights 'Haunted' Housing in Our 'Insidious' Sweepstakes!
Subscribe to PopCrush on
What would you do if you encountered an insidious entity?
In honor of the terrifying third chapter in the horror movie series Insidious, Focus Features is partnering with PopCrush to give three lucky winners and their guests a flyaway trip during three of this summer's hottest music festivals, as well as two nights of "haunted" housing and transportation.
What do we mean by "haunted" housing? Well, we know how hard it is to find a bed to crash in when you're traveling during summer festival season, so we got you a place to stay. The only catch is, it's legit haunted. From reported sightings of entities floating down the halls to doors that open and close on their own, these houses are bound to make your festival experience that much more memorable — if you think you have what it takes to spend the night.
The first Insidious house and prize pack you can enter for a chance to win is a trip for two to Las Vegas' Rock in Rio music festival during the weekend of May 15 — headlined by Taylor Swift and Bruno Mars! You'll stay at the Rocking Chair House, where the ghost of Rita McGill is said to continue her daily routine — and doesn't like to be interrupted by uninvited visitors. Guests have reported seeing her rocking chair rock through the night, finding cups of hot coffee that never get cold, and have woken up tucked into their beds so tightly they felt they were being suffocated.
To enter, show us how you would react if you came face to face with an insidious entity like the one in the films. Upload your reaction to Twitter, Instagram or Vine, using hashtag #InsidiousScareDare. You can add the URL in the entry form below to unlock additional entry opportunities. Whether you'd be totally terrified or a true hero, we want to see those faces! (If we came fact to face with a ghost we'd hide under our desks; we're lovers, not fighters here at PopCrush.)
You'll have the chance to win tickets and "haunted" housing at two more hot summer festivals in New York City the weekends of May 23 and June 5. Make sure to check back here on PopCrush for details on how to enter.
Written and directed by franchise co-creator Leigh Whannell, Insidious: Chapter 3 is a chilling prequel set before the haunting of the Lambert family. The story reveals how gifted psychic Elise Rainier (Lin Shaye) reluctantly agrees to use her ability to contact the dead in order to help a teenage girl (Stefanie Scott) who has been targeted by a dangerous supernatural monster.
Watch the trailer above for some horrifying inspiration, and don't forget to go see Insidious: Chapter 3 in theaters on June 5!
Enter to win the Prize Package via Instagram, Twitter, Vine and the widget below. The sweepstakes ends May 27 at 11:59PM PT. [Official Rules]

subset: commoncrawl


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Quick Details
- Standard or Nonstandard: Standard
- Structure: Ball
- Pressure: Medium Pressure
- Power: electric
- Material: Stainless Steel
- Temperature of Media: 0-100 Degree C
- Media: Water
- Port Size: 1''-4''
- Place of Origin: Shanghai, China (Mainland)
- Model Number: VC-QF
- Brand Name: CH-BA
- Application: HVAC
Packaging & Delivery
|Packaging Details
|Delivery Time
|Shipped in 7 days after payment
The QM/QF series of electric valve actuators are used in heating, ventilation, and air-conditioning (HVAC) applications. The QM series of electric valve actuators are modulating control actuators used with controls that provide an analog output of 0 to 10Vdc, 2 to 10Vdc or 4-20mA. The internal selector plug can be used to reverse the direction of action. The QF series of electric valve actuators are controlled by an on/off output.
l Low power consumption
l Position feedback by signal
l Direct/reverse acting
l 4-20mA/0-10V/2-10V choice
l Maintenance free
l Quick and easy installation
l No separate linkage required
l Accurate valve positioning
l Indicator Continuous Position Indicator
l Manual Override Non-clutch design
l Gear Permanently lubricated and self locking
l Stall Protection Built-in thermal protection


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Best of mixcraft 6 registra at KeyOptimize(Out of 57.6 Thousand in result | Last check 30 July 2017)
Your browser is deprecated. Please upgrade. - YouTube
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
Acoustica | Developers of Mixcraft 8
Acoustica developers of the award-winning Mixcraft music recording software. Acoustica makes the best and easiest to use recording software.
Electrofize Productions
My Website: http://electrofize.blogspot.co.nz/ THE UPDATE THAT CHANGED THE WORLD (This update includes 1.7 and 1.7.1) + Added lots of new biomes! - Removed the Rose flower - Removed Herobrine Posted by This is a Huge Premade server spawn which you can...
Discover recipes, home ideas, style inspiration and other ideas to try.
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Disqus – The #1 way to build your audience
Disqus offers the best add-on tools for websites to increase engagement. We help publishers power online discussions with comments and earn revenue with native advertising.
Phạm Chinh Đông | Những nhạc khúc viết bằng tình thương yêu có thật. Mãi mãi, Phạm Chinh Đông có một giòng sông êm đềm, những thác ghềnh trăn trở và một mùa ...
Kỷ Niệm Với Nhạc Sĩ ĐỖ HẢI Và Bạn Hữu Bài Ca Đất Phương Nam (Đỗ Hải trình tấu guitar) Quê Hương Tuổi Thơ Tôi (Đỗ Hải-Ngọc Minh) . PHẠM CHINH ĐÔNG và hiền thê HƯƠNG TRINH Hiện cư ngụ tại thành phố Philadelphia, tiểu bang Pennsylvania,Hoa Kỳ. Liên lạc: p...
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Moo.do is a notepad, a to-do list, and an outliner, but with advanced features that make the...
Created by MooDoApp
Okay, i have a lot of projects, and without todo-manager is imposible to manage all of them.
I have around 3-4k tasks for each project.
With Moo.do my life start to be much simplier then it was before.
Before Moo.do i was use TodoTxt (qtodotxt for windows), but it was not enough for me.
I found Moo.do somehow in internet (because of workflowy alternatives or something like that, did't remember when, but it's not important i guess).
So, my personal review about this software:
* Strongly recommend
* Very fast and simple
* Works offline with Google Application (it's important for me, because i'm not always have internet connection)
* There are very friendly interfaces and buttons (key combination)
* This project are free (but i plan to buy premium package later, when i got a little bit money)
What i really miss?
* i need to know how many tasks left, and how many tasks i have
* i really missing ctrl + c & ctrl + v shortcuts with saving structure of tasks (sometimes i need to copy-past all tasks from one list to another one)
* i need to enable / disable a time, when this task was created
* maybe if it possible -> make stand alone application for windows / linux / mac (google app is good, but not enough)
I will use this application without features above, it's not critical for me, because Moo.do helping me a lot to know what i've done, and what i must to do.
Sorry please for my very poor english (i'm not american, and my native language is russian).
So, i really suggest to use this application. Just try guys, and you will love it.


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M-Max 820 EP/USO consists of two rugged industrial computers with the highest performance currently available for systems with passive cooling. It is designed to provide reliable operation using '2 out of 2' or redundant architectures in harsh environments for critical applications. The fully-ruggedized rackmount aluminum chassis is fanless and utilizes natural convection and conduction cooling in accordance with MIL-STD-810 standards.
Providing shock and vibration protection, the M-Max 820 EP/USO can operate under extreme temperatures (-40 to +55 °C), dust and humidity. Delivering excellent performance due to Intel Core i7 CPUs (2.1-3.0 GHz), it also features excellent 2D and 3D graphics capabilities via VGA interface. Data storage options include vibration proof industrial SSDs with RAID functionality. The computer is used as a part of a safety system at railroad and operate as an optical time-domain reflectometer.
MicroMax, as a manufacturer of highly rugged industrial computers, takes a customized approach to each client and can provide even a single copy development and production.
|Technical specifications
|(per each subsystem)
|Intel Core i7-2715QE (2.1-3.0 GHz, 6 MB L2 cache, FSB 1066 MHz)
|Intel QM67
|2 GB DDR3 533 MHz (soldered on board) Expandable to 8 GB at the time of order
|Data storage
|SSD up to 1 TB (SATA) Hardware RAID 0/1 (option)
|Integrated controller: Intel HD Graphics 3000 with AVX Up to 512 MB dedicated memory Supports analog displays with resolution up to 2048 x 1536
|1x SNC28-3 (Power) 2x LTW (Ethernet) 1x SNC-28-32 (VGA, 2x USB 2.0) 1x PX0842 (USB) 2x DB-9 (RS-232) 1x SNC-28-4 (2x CAN) All connectors are IP66 or higher
|2x 10/100/1000Base-T
|Serial ports
|2x RS232
|3x USB 2.0, up to 8x USB 2.0 (optional)
|Keyboard and mouse
|+9 to +33 V DC (isolated) AC adapter ~100 to 240 V (optional)
|Special features
|Watchdog timer
|Power Consumption
|Power ON & Failure indicators
|Power ON button
|Aluminum enclosure Passive cooling system (no fans)
|Environmental and physical specifications
|Mechanical (W x H x L)
|480 x 173 x 241 mm
|Operating Temperature
|-40 to +55 °C, Complies with MIL-STD-810G (High temp. method 501.5, A1; Low temp. method 502.5, C1, Expandable to C2/C3)
|Operating: 5 to 95 % at +25 °C, non-condensing
|Operating acceleration amplitude up to 2,5g Complies with MIL-STD-810G (Method 514.6 for Ground vehicles and Aircraft)
|Maximum peak shock acceleration up to 40g Complies with MIL-STD-810G (Method 516.6 for Ground equipment and Aircraft)


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CBS Uses Ice Bucket Challenge to Tout Dem Slamming 'Cold' GOP
More in the cross-post on the MRC's NewsBusters blog.
During a report on Friday's CBS This Morning about some of the "backlash" against the ALS Ice Bucket Challenge, correspondent Ben Tracy highlighted Michigan Democratic Congressman John Dingell bashing Republicans who took part in the effort to raise research money for Lou Gehrig's Disease.
Tracy declared that Dingell "accuses some Republicans of de-funding ALS research while taking the ice bucket challenge. He tweeted, 'Since 2011, House Republicans have cut National Institutes of Health funding by billions. And you thought dumping ice water on your head was cold.'" Footage ran of Congressman Paul Ryan getting doused with ice water as Tracy recited Dingell's attack.


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Our "sexpert" points her trusty arrow at the year's most romantic day.
WebMD Feature
Q: How can I turn Valentine's Day into a romantic date worth remembering?
A: I can suggest a number of tips for making the most of Feb. 14. The most important, however, is to make the holiday a celebration of your relationship.
First, be tuned in to your mate's picture of Valentine's Day. Some couples like to share a romantic dinner, some exchange greeting cards, others want sexy lingerie to be given and worn.
Valentine's Day may have evolved into the idea of men buying women lots of jewelry, flowers, candy, and lingerie, but I think a shared experience, where women give as much as men, is the better approach. Still, talk about your romantic expectations beforehand to minimize disappointment. Differing ideas can cause a little heartbreak.


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text:
Aluratek ADMPF119 19" Digital Photo Frame - 1440 x 900, 16:10, 2GB Internal, SD Card Slot, USB, BlackItem#: A617-1212 | Model#: ADMPF119
Currently Out Of Stock!
You May Consider This Alternative
Additional Resources
Aluratek ADMPF119 19" Digital Photo Frame Product Details
Additional Resources: Product Manuals
Related ItemsPrevious
Manufactured by: Aluratek
Warranty provided by: Aluratek
UPC No: 812658010740
Mfg Part No: ADMPF119
Box Size:
( Length:23, Width:4, Depth:20)
Shipping Weight: 15.0500 pound(s)
Click here for full warranty and support information
- Aluratek logos are registered trademarks of Aluratek. All others trademarks and copyrights mentioned herein are the property of their respective owners.


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- Rinse and dry chicken
- Season liberally with salt and fresh ground pepper
- Heat large heavy duty pot with a lid – example – Le Creuset
- Add canola oil and allow to coat bottom of pot
- Add chicken skin side down-4 pieces at a time in order for a good sear. Turn over and brown other side and remove from pot. Repeat with rest of chicken
- Remove pot from heat and pour off some of the oil. Leave enough in pot to lightly sauté vegetables.
- Replace pot onto heat and add all vegetables except the kale.
- Season with salt and pepper and stir.
- Add white wine and chicken stock and stir. Scraping any bits off the bottom of the pot. When liquid begins to boil, place chicken pieces skin side up into vegetable mix. Chicken pieces should be able to fit into veggies snugly.
- As liquid begins to simmer, turn heat to low and cover the pot. Pot should be simmering, not boiling.
- Cook covered about 30 to 40 minutes. To test for doneness, you can feel the chicken should be firm to the touch and if needed, take a knife and cut into largest piece and pierce – juice should run clear.
- When chicken is finished, remove from pot and add kale.
- Cover pot and let simmer for about 5 more minutes.
- Turn off heat, uncover, remove cheese cloth packet. Taste your broth and season as needed with salt and pepper.
- Potatoes and carrots should be cooked through.
- Place chicken back in pot, bring to your table and place on a liner and serve.
- Sprinkle some fresh lemon juice on top.
One Pot Slow Cooked Meal
White Wine Braised Chicken with Fennel & Kale Servings: 4 Ingredients: 6 lb. whole chicken cut in 8 pieces (remove back bone, wings, giblets and neck) 6 medium carrots – cut in pieces, about ½ inch slice 1 medium brown onion – slice in ½ inch julienne 1 medium leek – cut in rings and rinsed to remove dirt 12 fingerling potatoes – cut in ½ inch pieces - rings ½ piece fennel, core removed, cut in chunks 1 bunch kale – stem removed, cut in chunks 4 cloves garlic 3 bay leaves 2 sprigs rosemary Thyme – small handful 1 cup white wine 1 cup chicken stock Salt Fresh ground pepper 2 Tbs. canola oil Cheese cloth Preparation:


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Slugtrail Video MP3
Slugtrail video for the song "Lick" .
"slugtrail" Official Music Video - Adelaide MP3
2013 Music Video from the ep "slugtrail" LYRICS: Familiar thoughts seem to drain throughout pipes of anesthetized subconcious Chock full to the brim of the ...
Slug Trail Game walk-through for teachers MP3
This video goes with How to Teach Primary Programming Using Scratch http://code-it.co.uk/scratchbook A video walk-through of the Slug Trail Game in Chapter ...
Adelaide - Slugtrail MP3
Check them out: http://www.myspace.com/adelaidetn Check out my Facebook Site : https://www.facebook.com/pages/Proclaim-Gods-Name/185877334937558 ...
MALDI Imaging of gastropod (Snail\ slug) trail MP3
This video illustrates the ability of MALDI imaging to view the chemicals that make up the mucal trail of a snail. This technique can be used to examine the ...
Slimy Slug, A Slug Trail and Other Little Creatures MP3
Working in the yard, I uncovered this board to reveal an abundance of life underneath. I noticed the rather large slug and decided to record. I walked away for 30 ...
Unlocking AVP Classic Cheat Modes: SlugTrail MP3
avp classic cheat option Slugtrail MP3
aliens versus predator classic Cheat option: Slug Trail Description: All aliens are missing a leg. That's basically it. They crawl around and are easier to shoot.
The Binding of Isaac: Rebirth [5] SLUG TRAIL #LetsGrowTogether MP3
Get it? Because slime? hah. Buy The Binding of Isaac Rebirth on steam, at store.steampowered.com/app/250900/ #LetsGrowTogether.
Banana Slug Trail Trials - Net Control MP3
Slug Trail Art MP3
This is what the slugs did last night. It's like graffiti, only shinier!
Lick by Slugtrail (music Video) MP3
Music video by the late, great Columbia, Missouri band Slugtrail.
Slugtrail MP3
Provided to YouTube by CDBaby Slugtrail · Adelaide Slugtrail ℗ 2013 Adelaide Released on: 2013-02-22 Auto-generated by YouTube.
Banana Slug Trail MP3
Provided to YouTube by CDBaby Banana Slug Trail · Rob Hart Trio Trios of the Past Present and Future ℗ 1999 Rob Hart Trio Released on: 1999-01-01 ...
Banana Slug Trail MP3
Provided to YouTube by CDBaby Banana Slug Trail · Rob Hart Trio Art of Improvisation ℗ 2006 rob hart Released on: 2006-01-01 Auto-generated by YouTube.
Gauss DX VATS Slug trail MP3
weijiesen's Gauss DX mod for Fallout 3 - Slug trail seen in certain VATS critical hits. Notice the projectile penetrates the target! All Gauss visual effects brand ...
Barnes 62 Cal Airgun: Yukon Orion - showing Contrails and Plume from Slug Trail MP3
This is the Barnes Orion 62 Caliber PCP Air Gun. It's shooting a 600 grain slug. Energy is approx. 650 foot pounds with this slug. On this particular day, ...
Slugtrail MP3
Banana slug trail MP3
Slugtrail @ Eastside Tavern(Liz's going away party) 5-29-10 MP3
Slug trail. MP3
Slug trail MP3
Slugtrail(Dio cover) @ Eastside Tavern(Liz's going away party MP3
Slugtrail @ Eastside Tavern(Liz's going away party) 5-29-10 MP3
Road slug trail's on CSX equipment train MP3
Slug trail lap frog pimp MP3
Our fun group at Banana Slug Trail Trials MP3


text: Viewing Bruce Springsteen - 1 of 2 "Do Your Job" by Bruce Springsteen Immortal Bruce Springsteen is fed up with the working class. This is his new single "Do Your Job" Pete Hulne June 16, 2008 140k Views More Info Full Credits Pete Hulne Uploader Additional Credits Pete Hulne as Bruce Springsteen. Music Composed by John LaMantia. Lyrics by Jim Wise and Pete Hulne. Shot and Edited by Rob Soucy. Stats & Data 3,420Funny852Die 139,065 Views June 16, 2008 Published Category Clean Comedy Music Parody Tags Bruce Springsteen Fed Up Pete Hulne Jim Wise Do Your Job working class rage The Boss Peter Hulne middle class war diner fat america Up Next: "Bruce Springsteen's American Dream" AUTOPLAY Up Next In: 10 "Bruce Springsteen's American Dream" "Do Your Job" by Bruce Springsteen Republican Bruce Springsteen For Labor Day We Asked: "Why Is The Working Class So Lazy?" Follow Browse Related Comments Bruce Springsteen 2+ more View All ▶ 3+ more View All ▶ Pete Hulne Vaguely Related Videos Vaguely Related Pics & Words Advertisement Tags: Bruce Springsteen Fed Up Pete Hulne Jim Wise Do Your Job Pete Hulne Advertisement


text:
Schools & Colleges
Office: North Classroom, Room 2014-BTelephone: 303-556-2849E-mail: email@example.com Website: www.ucdenver.edu/faculty-staff/jguo
Hydrology and hydraulics
Curriculum Vitae: Download
© The Regents of the University of Colorado, a body corporate. All rights reserved.
Accredited by the Higher Learning Commission. All trademarks are registered property of the University. Used by permission only.


text:
Sky Sports News racehorse On Demand third at Southwell
On Demand, the Sky Sports News racehorse, finished third on her second racecourse appearance at Southwell.
Last Updated: 09/02/14 10:09pm
Trained by Andrew Balding and ridden by David Probert, she tracked leader Captain Swift into the home straight.
However in behind the well-backed Tigers In Red began to make his move and was soon in front for an impressive success.
The 5/2 second favourite was followed home by Moonlight Venture (8/1) who finished strongly to pass On Demand close home.
The latter, sent off the 5/4 favourite, was having her first run since September and is expected to improve for it.


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Survival in low-oxygen environments requires adaptation of sympathorespiratory control networks located in the brain stem. The molecular mechanisms underlying adaptation are unclear. In naïve animals, acute hypoxia evokes increases in phrenic (respiratory) and splanchnic (sympathetic) nerve activities that persist after repeated challenges (long-term facilitation, LTF). In contrast, our studies show that conditioning rats to chronic hypobaric hypoxia (CHH), an environment characteristic of living at high altitude, diminishes the response to hypoxia and attenuates LTF in a time-dependent manner. Phrenic LTF decreases following 7 days of CHH, and both sympathetic and phrenic LTF disappear following 14 days of CHH. Previous studies demonstrated that GABA is released in the brain stem during hypoxia and depresses respiratory activity. Furthermore, the sensitivity of brain stem neurons to GABA is increased following prolonged hypoxia. In this study, we demonstrate that GABAA receptor expression changes along with the CHH-induced physiological changes. Expression of the GABAA receptor α4 subunit mRNA increases two-fold in animals conditioned to CHH for 7 days. In addition, de novo expression of δ and α6, a subunit normally found exclusively in the cerebellum, is observed after 14 days. Consistent with these changes, diazepam-insensitive binding sites, characteristic of GABAA receptors containing α4 and α6 subunits, increase in the pons. Immunohistochemistry revealed that CHH-induced GABAA receptor subunit expression is localized in regions of sympathorespiratory control within the pons. Our findings suggest that a GABAA receptor mediated-mechanism participates in adaptation of the sympathorespiratory system to hypobaric hypoxia.
- hypoxia
- plasticity
- sympathorespiratory network
neural networks that control homeostasis are plastic. Adaptation to reduced oxygen at high altitude requires days-to-weeks of continuous exposure (2, 24, 29, 30, 38). This adaptation involves both peripheral and central control mechanisms that maintain homeostasis. Central sympathorespiratory control networks express short-term plasticities elicited by brief (45 s) hypoxic challenges. These plasticities result in different sympathorespiratory motor output after challenges are terminated. Two types of behaviors are evoked depending on the pattern of acute hypoxic challenges. A single challenge elicits a transient (min) decrease in respiratory frequency termed posthypoxic frequency decline (PHFD) and increases respiratory effects on sympathetic nerve activity (9, 12). Multiple challenges elicit a sustained (h) increase in sympathorespiratory motor output termed long-term facilitation (LTF) (1, 18). Exposure to chronic hypoxia (days) attenuates PHFD, whereas its effect on LTF is unknown (16, 18). Prolonged hypoxic exposures also increase tyrosine hydroxylase expression in brain stem catecholaminergic cells (14, 28, 34, 35). Although these changes in sympathorespiratory motor patterns are mediated by brain stem nuclei, the neurotransmitters involved and the interplay among these nuclei are not fully identified.
The pons, a brain stem region, contains nuclei that participate in the expression of PHFD and LTF. We previously demonstrated that cells in the ventrolateral (vl) pons mediate PHFD. Disrupting activity in this region blocked PHFD without affecting the respiratory response during acute hypoxia (9, 20). Furthermore, stimulating the A5 neuronal population increased splanchnic sympathetic nerve discharge (17). Cells in the ventromedial pons (caudal raphé) project to sympathorespiratory motor nuclei and mediate LTF (25, 26, 37). The contribution of these pontine nuclei to the adaptation to chronic hypobaric hypoxia (CHH) has not been investigated.
Many findings suggest that the response and adaptation to hypoxia depend on the GABAergic system. During hypoxia, GABA is released in brain stem regions involved in the control of homeostasis (32). Furthermore, bilateral microinjections of a GABAA receptor agonist, muscimol, in the vl pons blocks PHFD (9). In contrast, injection of a GABAA receptor antagonist, bicuculline, alters the hypoxic response (16). Finally, we previously found that the mRNAs encoding the GABAA receptor α6 and δ subunits are expressed de novo and exclusively in the pons after 2 wk of CHH (16).
To delineate the role of GABAergic system in the physiological adaptation to CHH, we compared the temporal relationship between changes in activity-dependent plasticity (LTF) and GABAA receptor expression. We report that CHH-elicited attenuation of LTF is associated with induction of the expression of select GABAA receptor subunit mRNAs in pontine nuclei involved in sympathorespiratory control. These changes include an increase in the α4 subunit and de novo expression of the α6 and δ subunits. The upregulation of subunit mRNA expression is associated with an increase in GABAA receptor number in the pons. In addition, the α6 subunit polypeptide was expressed only by cells in the raphé and vl pons. These findings suggest that GABAA receptor plasticity contributes to adaptation to hypobaric hypoxia.
Adult male Sprague-Dawley (Zivic Miller, Zelienople, PA) rats (280–320 g) were maintained in hypoxic (n = 56) or normoxic conditions (n = 12), or left in naïve state (n = 12). The hypoxic group was placed in a hypobaric chamber simulating hypoxia at high altitudes (0.5 atm) for 3, 7, or 14 days. Normoxic animals were placed in the chamber without hypoxic exposure for similar times. Animals were placed on a circadian light-dark cycle, had free access to food and water, and were inspected daily. The hypobaric chamber was opened 2 or 3 times a week to clean cages and to replenish food and water; during this period of about 15 min, the animals were at the normal barometric pressure (∼1 atm). Naïve animals were never placed in the chamber.
The hypoxic response and long-term facilitation (LTF) in the anesthetized in vivo rodent preparation were assessed as previously described (9, 16). All surgical and experimental protocols followed National Institutes of Health guidelines and were approved by the Institutional Animal Care and Use Committee. In brief, immediately after hypobaric hypoxic conditioning, animals were anesthetized with equithesin (30 and 133 mg/kg pentobarbital sodium and chloral hydrate, respectively), and the anesthetic level was evaluated by assessing the withdrawal reflex before neuromuscular blockade and by assessing the cardiorespiratory response after neuromuscular blockade (pancuronium bromide −0.1 mg/100 g body wt). If responses were evoked by nociceptive stimuli, then anesthesia was supplemented by intravenously administering one-tenth of the initial dose. Neuromuscular blockade was supplemented hourly also by intravenously administering one-tenth of the initial dose. The femoral artery and vein were cannulated to monitor blood pressure and administer pharmacologic agents, and the trachea was cannulated to ventilate the animal. The cervical vagi were isolated and transected bilaterally to prevent afferent feedback. The left phrenic and splanchnic sympathetic nerves were isolated, transected, and mounted on bipolar electrodes for recording. Animals were ventilated with 100% O2 before and after the hypoxic challenge. Elevation in splanchnic sympathetic and respiratory activities was increased by exposure to 10 hypoxic challenges (8% O2 for 45 s with a 5-min recovery period). The exposures were poikilocapnic and end-tidal Pco2 decreased less than 2 mmHg during this brief hypoxic exposure.
Quantitative analysis of respiratory and sympathetic responses to hypoxia.
Breathing pattern was measured by assessing phrenic nerve activity (PNA). Onset of PNA was the point on the positive slope of the integrated PNA signal that was 10% above the interburst value. Offset of PNA was identified on the negative slope of the signal that was 25% below the peak value. The end of the cycle was identified as the onset of the next breath. The peak activity of PNA was averaged for 10 cycles immediately before starting the 10 cycles of intermittent hypoxia, in the 5-min recovery period between the 9th and 10th acute hypoxic stimuli and 1 h after the 10th acute hypoxic stimulus.
Quantitative analysis of splanchnic sympathetic nerve activity (sSNA) was based on cycle-triggered averages (CTA) constructed to compare the coupling patterns between PNA and sSNA. Averaging increased the signal-to-noise ratio of sSNA that was time-locked to the respiratory cycle (12). For averaging, the analog signal of sSNA was rectified, integrated (CWE, Wood Dale, IL; Paynter Filter, 50-ms time constant), sampled at 200 Hz, and summed (National Instruments, Analog-to-Digital board, Austin, TX). The reference point (time 0) for CTAs was the phase transition between inspiration and expiration.
The average amplitude under the curves was calculated for PNA and sSNA. The inspiratory and expiratory portions of the sSNA cycle-triggered averages were divided in half, thereby allowing direct comparison of the magnitude of sSNA. The significance of observed differences in values proceeding and following repeated acute hypoxic exposures were determined by two-way ANOVA for repeated measures. The factors for the two-way repeated-measures ANOVA were 1) subject (the animal), 2) days of conditioning, and 3) time point (before the acute hypoxic exposure, 5 min between the 9th and 10th exposures, and 60 min after the 10th acute hypoxic exposure). The variables, area of integrated PNA, and average amplitude of integrated sSNA in the first and second halves of inspiration and of expiration were ranked and transformed to pass the normality test. Significant differences within variables were identified by the Student-Newman-Keuls test. To identify significant correlations among sSNA and PNA, linear regression analysis during the first and second halves of each phase was performed and values of P ≤ 0.05 were taken as significant. Data are presented as means ± SE as indicated.
RNA isolation and RT-PCR.
Relative levels of GABAA receptor subunit mRNAs in normoxic and hypoxia-exposed animals were determined using a semiquantitative RT-PCR protocol essentially, as previously described (3, 4, 33). In brief, the pons, medulla, thalamus, and cerebellum were dissected from brains of euthanized animals after the indicated exposure to CHH (naïve rats were housed in the chamber with airflow but not hypobaric pressure). Pontine tissue was dissected using the following landmarks: rostral-caudal to the inferior colliculi (dorsal) and rostral to the pontine gray (ventral); caudal-adjacent to origins of cranial nerves V, VI, VII, and VIII (the inferior border of the pontine prominence). RNA was extracted from all samples using TRIzol, according to manufacturer's (Invitrogen, Carlsbad, CA) protocol, reverse transcribed, and processed for PCR using GABAA receptor subunit-specific primers in buffer containing [α-32P] dCTP. The expression of GAPDH and 18S RNAs were also quantified as internal controls. All experiments were performed at least six times using tissue prepared from different animals.
The PCR products were separated on 8% nondenaturing polyacrylamide gels, which were dried and detected with a Molecular Dynamics Phosphorimager. The band intensities were quantified using ImageQuant Software (Molecular Dynamics, Sunnyvale, CA). To compare mRNA expression in the different experimental conditions, the intensities of the receptor subunit mRNAs were normalized to the intensity of either the GAPDH or 18S bands in the samples. Significant differences in receptor subunit mRNA levels in naïve vs. hypoxia-conditioned animals were assessed by applying a two-way ANOVA (Sigma Stat 2.03). Specific differences were then identified using Student-Newman-Keuls post hoc test. Primer sequences are shown in Table 1.
Ligand binding assay.
Membranes from the pons, medulla, thalamus, and cerebellum of hypoxia-conditioned and normoxic rats were harvested, and binding assays were performed using the benzodiazepine partial inverse agonist [3H]Ro-15-4513 (Perkin-Elmer, Waltham, MA), a ligand that recognizes diazepam-insensitive sites characteristic of GABAA receptors containing α6, α4, and ε subunits. Naïve and CHH-conditioned rats were euthanized by exposure to hypercapnic hypoxia. Protein extraction was performed as previously described (39). Samples (50–300 μg of protein) were incubated with saturating concentrations of 10 μM diazepam and the indicated concentrations of [3H]Ro15–4513 for 1 h at 4°C and harvested on nitrocellulose membranes using 50 mM Tris·HCl, pH 6.9 and counted. GraphPad Prism (3.0) software was used to fit the data and to a one-site binding hyperbola. The data represent values obtained from three assays in five different animals from each hypoxic exposure period.
For immunostaining, control and hypoxia-exposed rats were euthanized and immediately perfused via cannulation through the left ventricle with 100 ml heparinized (20 units/ml) 10 mM saline followed by 200 ml 4% paraformaldehyde in 0.1 M PBS, pH 7.4. The brains were removed, postfixed at 4°C overnight, transferred to 30% sucrose in PBS at 4°C, and then stored at −80°C until use.
Coronal sections (15 μm) were cut through the entire brain stem and mounted on poly-l-lysine slides. The sections were permeabilized in PBS containing 0.3% Triton X-100 and 5% BSA for 1 h. Sections were then incubated in dilution buffer containing the antibodies against the α6 subunit at 1:200 (Chemicon, Temecula, CA) and tryptophan hydroxylase at 1:1,000 (Chemicon) for 3 h at room temperature. Western blot analysis demonstrated that the α6 antibody recognizes a single band of the appropriate molecular weight in the cerebellum of naïve rats, supporting its specificity. After incubation, the sections were rinsed three times in PBS and incubated with species-specific secondary antibodies at 1:500 (Jackson Immunoresearch Laboratories, Bar Harbor, ME) for 1.5 h at room temperature. After washing three times for 10 min in PBS, sections were mounted and examined with a Nikon FX microscope. Background staining was determined by incubating adjacent sections with a secondary antibody alone. Images were collected from experimental and control samples prepared from at least four different animals.
CHH induces alterations in the sympathorespiratory response to acute hypoxia.
Exposure to brief hypoxic stimuli elicited changes in sympathorespiratory activity. In naïve rats, repeated acute hypoxic challenges (n = 10) augmented both sSNA and PNA during the stimulus period (Fig. 1A, compare left to middle panel). The elevation in sSNA and PNA remained 1 h after cessation of the hypoxic challenges, indicative of LTF (Fig. 1A, right).
Conditioning to CHH altered the sympathorespiratory response to acute hypoxic challenges in a time-dependent manner. After 3 days of conditioning, acute hypoxia increased sSNA as in naïve animals (Fig. 1B, middle); in contrast, PNA did not increase. Both motor outputs, however, augmented progressively following cessation of the hypoxic challenges (Fig. 1B, right) and thus exhibited LTF. In contrast, after 7 days of CHH, sSNA and PNA were affected differently by acute hypoxic stimuli; LTF persisted in sSNA, but was absent in PNA (Fig. 1C). After 14 days of CHH, the repetitive acute hypoxic stimuli failed to augment either sSNA or PNA, and as a result, LTF of both activities (evident 1 h after cessation of acute hypoxic challenges) was not evoked (Fig. 1D).
Sympathetic and respiratory hypoxic responses were quantified by examining the effects of CHH on the average amplitude of integrated sympathetic activity and the peak amplitude of integrated phrenic nerve activity. Analysis of sSNA was based on the respiratory pattern. In naïve animals, the amplitude of sSNA was elevated most notably during the first half of expiration (sE-1), and this increase persisted 1 h after cessation of repetitive acute hypoxic challenges (Fig. 2A, top). The rise in sSNA during sE-1 roughly paralleled increased PNA (Fig. 2B, top). After 3 days of CHH conditioning, sympathetic activity increased uniformly across the respiratory cycle and exhibited an enhanced LTF (Fig. 2A, second panel). In contrast to the individual animal shown in Fig. 1, group data showed that PNA did increase immediately after the acute hypoxic challenges after 3 days of CHH conditioning. Similar to the individual animal's tracing, group data showed robust LTF after 1 h of recovery (Fig. 2B, second panel). After conditioning for 7 days, sSNA was recruited primarily in the second half of inspiration (sI-2) during hypoxic challenge (Fig. 2A, third panel). Further, expression of LTF within PNA was abrogated completely (Fig. 2B, third panel). After 14 days of CHH, acute hypoxic challenges failed to elicit increases in sympathetic and phrenic activities, either during the challenges or after 1 h of recovery (Fig. 2, A and B, bottom), at which time LTF was clearly evident in naïve rats. This analysis clearly demonstrates that CHH conditioning differentially affects the temporal changes in the patterns of sSNA and PNA. In addition, 14 days of CHH conditioning was required to abolish LTF completely in both classes of motor activity.
Altered pontine GABAA receptor subunit expression accompanies CHH-induced changes in the sympathorespiratory response.
To determine whether GABAA receptor expression in the brain stem could contribute to the CHH-induced plasticity of sympathorespiratory responses, we measured receptor subunit mRNAs in regions involved in their control. GAPDH mRNA expression in the brain stem tissue remained consistent throughout the hypoxic period. Within 3 days of CHH and parallel with the onset of the delay of LTF in PNA, the level mRNA expression for the GABAA receptor α4 subunit rose twofold in the pons; its level remained elevated throughout the experimental period (Fig. 3A). After 14 days of CHH and coinciding with attenuation of the sympathetic response to hypoxia (Figs. 1 and 2), robust de novo expression of the mRNAs encoding the α6 and δ subunits in the pons; neither subunits were detectable in naïve or normoxic (not shown) animals. In contrast, expression of the β2 subunit mRNA, which is abundant in this brain region, did not increase either during or after CHH. In addition, CHH failed to induce the expression of the ε subunit, a subunit that confers properties similar to those of the α4 and α6 subunits. These observed changes in GABAA receptor subunit mRNA were not observed in the medulla (Fig. 3B).
To show that elevated expression of subunit mRNAs was associated with increased GABAA receptor number, receptor levels were measured by radioligand binding. Because the α4 and α6 subunits contribute to receptors that are insensitive to diazepam, binding was assessed with [3H]Ro 15–4513, a ligand selective for these sites. These studies demonstrated that the diazepam-insensitive sites rose progressively within the pons during CHH. [3H]Ro 15–4513 binding was unaltered after 3 days of hypoxia but then increased by 250% and 500% over the control level after 7 and 14 days of CHH (Fig. 4A). The Kd of Ro 15–4513 binding was the same in animals exposed to all periods of CHH (Fig. 4B and Table 2), indicating that receptor affinity is unaltered.
The CHH-induced increase in receptor concentration was restricted to the pons. No changes in diazepam-insensitive binding were seen in the medulla, in agreement with the lack of detectable changes in subunit mRNA expression in this region (data not shown). In addition, CHH did not alter receptor binding in the cerebellum, the only brain region in which the α6 subunit is expressed in naïve animals. The concentrations of diazepam-sensitive receptors in the pons, medulla, and cerebellum were likewise unaffected by CHH (data not shown), underscoring the selectivity of the CHH-induced elevations of pontine Ro 15–4513 binding.
Finding GABAA receptor α6 subunit mRNA expression in the pons is novel and surprising. To localize expression of this subunit, α6 polypeptide distribution was examined immunohistochemically. As expected, α6 subunit staining was not detected in the pons of naïve animals (Fig. 5B) or in animals exposed 3 and 7 days to CHH (data not shown). In contrast, subunit-expressing cells were found after 14 days CHH when the subunit mRNA was first detected (Fig. 3). At this time, α6-subunit-positive cells were found in an area in the vl pons containing A5 adrenergic neurons (Fig. 5, C and D), cells involved in sympathorespiratory control. In contrast, staining was absent from the pontine reticular formation and the medulla (not shown). As expected, α6 subunit expression in cerebellar granule neurons was unaltered by CHH (Fig. 5, E and F).
Additional studies demonstrated that the α6 subunit was expressed in ventromedial pons. Following 14 days of CHH, positive cells were detected in the raphé pallidus (RPa; Fig. 6A). The staining was colocalized with serotonergic cells containing tryptophan hydroxylase. Previous studies have shown that this region contains elements of the respiratory neural control network. Together, these findings suggest that GABAA receptors containing the α6 subunit participate in reshaping LTF in response to repetitive hypoxic challenges.
The association of de novo GABAA receptor subunit expression and the absence of plasticity in the motor activity is consistent with the GABAergic system partially mediating the physiological adaptation of adult rats to CHH. These studies demonstrate that the sympathorespiratory plasticity evoked by acute intermittent hypoxia depends on the number of days of conditioning in hypobaric hypoxia. Concurrent with these physiological changes, GABAA receptor expression is upregulated in pontine nuclei that participate in sympathorespiratory control.
Our physiological results reveal that CHH attenuates sympathorespiratory LTF in a time-dependent manner. The loss of respiratory LTF (PNA) occurred progressively. Acute hypoxic challenges triggered an increase in PNA in naïve and 3-day CHH-conditioned animals; however, the onset of this change could be delayed in animals exposed 3 days to CHH (comparing Figs. 1 and 2). By 7 days, respiratory LTF was abolished, a change that remained at 14 days. In contrast, the change in sympathetic LTF was much slower, with no attenuation detected until 14 days of CHH. These temporal disparities in the effects of CHH suggest that sympathetic and respiratory LTF are differentially regulated.
In support of the role of GABAergic system in the adaptation to CHH, our studies demonstrate that expression of a subset of the GABAA receptor subunits is upregulated or induced in pontine nuclei by this stress. Our findings suggest that GABAA receptors containing the α4, α6, and δ subunits are critical for adaptation due to their temporal and spatial patterns of expression. At 3 days, the increase in α4 subunit mRNA expression coincides with the decrease in respiratory LTF. By 14 days, the de novo expression of the α6 and δ subunits mRNAs in the pons coincides with the absence of activity-evoked plasticities. Cells expressing the α6 polypeptide appeared exclusively in the raphé and vl pons, regions of sympathorespiratory control. This finding is novel because the α6 subunit is restricted to cerebellar granule neurons in naïve adult rodents. Finally, it is striking that no changes in subunit expression were observed in the medulla, the region containing the central respiratory pattern generator.
In agreement with changes in GABAA receptor subunit expression, GABAA receptor number was upregulated in the pons. Most importantly, the number of diazepam-insensitive GABAA receptors increased. This is consistent with the fact that the α4 and α6 subunits confer diazepam insensitivity. It is of interest that expression of the α6 and δ subunits was induced simultaneously. These two subunits have been shown to coexist in one GABAA receptor type (21, 27). The fact that the number of diazepam-sensitive sites did not change suggests that CHH induces the expression of a select type of GABAA receptor.
Both of our physiological and molecular findings implicate the importance of cells in the vl pons and raphé in mediating adaptation to CHH. Moreover, along with the anatomical and physiological findings of other investigators (8, 25, 36), our results support the importance of GABA and GABAA receptors in these regions for adaptation. In previous physiological studies, we demonstrated that bilaterally lesioning the vl pons and/or inhibiting activity in this region with injections of the GABAA agonist, muscimol, block PHFD (9) and attenuate the sympathetic response to hypoxia (22, 23). Conversely, stimulating the vl pons or blocking the GABAA receptor with the antagonist, bicuculline, increased the duration of expiration during hypoxia (16). Finally, recordings of vl pontine activity identified neurons that are activated during hypoxia and remain activated when the hypoxic stimulus is terminated (10).
It is surprising that a prolonged period (14 days) of CHH was required to induce α6 and δ subunit expression. We speculate that the delay in the expression of these subunits depends on the vital contribution of the peripheral mechanisms, such as the vascularization of carotid body and changes in circulating cerebrospinal fluid bicarbonate (28a). Furthermore, the delay may reflect the complex interactions between neurotransmitters (glycine, nitric oxide, glutamate, substance P, and GABA) that mediate the hypoxic response (5–7, 31).
In conjunction with the findings of other investigators, our findings raise the possibility that the GABAergic and serotinergic systems interact in the raphé to regulate LTF. Previous studies have shown that LTF is dependent on serotonin receptor activation and that systemic or intrathecal methysergide, a receptor antagonist, block LTF (11, 13, 15, 26). Moreover, the caudal raphé is the sole source of serotonin in the spinal cord, and serotinergic neurons in the raphé magnus project directly to the phrenic motor nucleus. Recent work has shown that the serotinergic and GABAergic systems interact in the raphé (8), a possibility supported by our immunohistochemical findings. It is possible that the signaling in the raphé provides a central, rather than peripheral, control of sympathorespiratory LTF motor activity. Our findings suggest that increased GABAA receptors in CHH animals decrease phrenic and sympathetic LTF by inhibiting activity in the caudal raphé.
On the basis of these findings, we present a model of the pathways involved in regulating LTF in naïve and CHH-conditioned animals (Fig. 7). In this model, pontine GABAA receptors play a key role in mediating the plasticity manifested by the sympathorespiratory hypoxic response. In naïve animals, hypoxic conditions detected by the carotid body cause signaling to the nuclei of the solitary tract, and this is relayed to both the pons and ventrolateral medulla. These sensory and initial transmission phases of the response to hypoxia are mediated by glutamate (19, 32). The sensory input returns to baseline following acute hypoxic challenges and ceases to drive respiratory and sympathetic activities. In contrast, pontine neurons in the raphé and A5 areas that are activated during hypoxia remain active after the challenge and mediate the expression of LTF (Fig. 7A, gray solid arrows). The extent of raphé and A5 activation is regulated by GABA (Fig. 7A, solid broken arrow). Consequently, during long hypoxic exposures, GABA is released after the initial response and acts to decrease ventilation partially by inhibiting these modulatory nuclei.
In contrast, exposure to CHH leads to upregulation of the expression of select GABAA receptor subunits within the raphé and A5 areas. This may be due to either a prolonged release of GABA or the feedback inhibition to the excitatory glutamergic input from the nTS. In any case, the change in GABAA receptor subunit expression alters the interplay between the GABAergic, serotonergic (raphé), and adrenergic (A5) neurons within this region. Thus, while these pontine nuclei excite the sympathorespiratory system following acute hypoxia in naïve animals, the enhanced GABA-mediated inhibition of these pontine subnuclei in animals exposed to CHH precludes the activation of PNA and sSNA, thus preventing LTF.
The model predicts that blocking expression of select GABAA receptor subunits within the pons prevents adaptation to CHH. Our study raises the possibility that the observed plasticity of GABAA receptor subunit expression within the pons represents a molecular basis of the neural mechanism for CHH-induced attenuation of both sympathetic and respiratory activities (Fig. 7B), an issue to be addressed in future studies using subunit-deficient animals. Furthermore, it is possible that with a return to normoxia, GABAA receptor subunit will be downregulated and the hypoxic response will return to that found in naïve animals. In the proposed model, the de novo expression of GABAA receptor subunits diminishes activation of neurons within the raphé and A5 area. We view this as an extension of the GABA-gain hypothesis, wherein both the neurophysiological properties and the plasticity of respiratory bursts is attenuated by increases in GABA-induced activity (40). Finally, we speculate that in pathophysiological states, including heart failure and obstructive sleep apnea, the accompanying sympathorespiratory dysfunction may be due in part to concomitant alterations in the expression of GABAA receptor subtypes within the pons.
Perspectives and Significance
Our studies provide new insights into the neural mechanisms mediating the plasticity of the sympathorespiratory neural network. Using both molecular and physiological approaches, we demonstrate that CHH exposure selectively alters GABAA receptor subunit expression in the pons and attenuates sympathorespiratory LTF. On the basis of these findings, we present a conceptual model that defines the role of GABAA receptor in the blunted LTF found in CHH-exposed animals. Future studies need to identify the relationship between LTF and the expression of specific GABAA receptor subunits in the raphé, pontomedullary regions known to evoke LTF. For example, does blocking expression of specific GABAA receptor subunits rescue LTF and reestablish sympathorespiratory plasticity in CHH conditioned animals? Furthermore, in CHH-conditioned animals, does a return to normoxia restore LTF and plasticity in the sympathorespiratory network? If so, is this due to the downregulation of GABAA receptor subunits? Answers to these questions will provide further information concerning the role of GABAA receptor plasticity in mediating adaptation of the sympathorespiratory system to chronic hypoxia.
This work was supported by grants from the National Institutes of Health HL25830, HL080318, and NS34317. We gratefully acknowledge the technical assistance of Ning Wang, Rishi Dingra, and Mallika Padival and critical review of the manuscript by Drs. Jeffery Tatro and Martin Snider.
The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
- Copyright © 2008 the American Physiological Society


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Hexagon Overview
Millions of dollars are invested in LiDAR data by government entities and private sector organizations. After delivery of LiDAR data is received the possibilities become endless on the geospatial information products that can be derived. This webinar covers how to extract geospatial information from LiDAR point cloud data.


text: TIES--made up of 48 Minnesota school districts--has been around for 46 years. And each year it's quite a wintry blast! Learn from and network with education technology practitioners and experts and discover the latest tools and solutions offered by over 100 vendors. Preconference workshops run from Dec. 14-15, followed by breakout sessions and keynotes on the 16-17. Various registration rates available from $95 to $300.


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Been seeing a guy for almost three months now, he is the sweetest guy I've ever met and I like him so much.
I can't find a single bad thing about him and honestly... It scares the shit out of me.
He bought me flowers when I had a cold, he tells me I'm beautiful every single day, we talk for hours, we have the same humour, love to cuddle, we love to banter and tease eachother and he is the first guy that I actually trust. He told me that he can't believe that I still want to see him, which is crazy because I feel the same way.
I've met his parents, friends, colleagues, he is talking about me with all of them, even his boss. He told me he is the relationship-kind of guy.
I've been burned a lot of times and I've had a hard time letting my guard down, I'm not one to express my feelings. When he told me that he is falling in love with me I went completely silent. I was taken by surprise, not only that he said it since his actions had already told me he at least was on the verge of, but mostly because I wanted to say it back. It's like everything else went blurry when he said it. When I didn't respond he apologized for telling me. I stopped him, kissed him and told him that I am falling in love with him too.
I'm scared out of my mind though. He is too perfect. I'm scared of getting hurt and I'm even more scared of hurting him. One of his colleagues told me he deserves the absolute best, something I've known all along, and I can't help but think that I'm not nearly enough. Which kind of makes me want out.
Has anyone else experienced it? What did you do? Any advice please?
Most Helpful Girl
Firstly, heal your past hurt or it will always get in the way.
Secondly, we all responds to these things differently, you are taking it slow and he seems to be a little ahead, so if you need to slow down then take a break. You don't need to say "I need a break from you" just say you are super busy cos of work and you might not respond to his messages for a week or two because if this. Take that time to breathe and analyse the situation and how you feel about everything.00|00|0
there's nothing wrong with you, everyone's different.
Maybe.. I just don't want to mess things up. I work at a clothes store so it wouldn't really work though. We text everyday, he is usually always the one initiating it, and I've realised that everytime I see that it's from him I'm grinning from ear to ear. I don't know if I want a break and if I tell him not to text me it'll definitely mess things up and he'll get hurt, which is absolutely the last thing I want.
Do you think it'd be a bad idea to continue on pretending like I'm not scared at all and hope that it'll all go away?
Thank you so much for your time :)
Okay, why don't you be more open with him instead? Tell him that you are afraid of getting hurt, it's good to communicate these things that way you will feel more relaxed.


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Happiness, Baby J has arrived! And I'm convinced that he is as sweet as they come. I'll be back blogging soon, but for now, I'll be spending my time with this little guy.
03 February 2012
yay, baby!
16 comments:
Aw, congrats! He is so sweet : )ReplyDelete
so precious and beautiful- congrats!ReplyDelete
congratulations! :)ReplyDelete
Congratulations on your sweet, little bundle of joy.ReplyDelete
amazing!! congratulations!!!!!!!!!!ReplyDelete
Congratulations on the healthy baby boy Lisa!ReplyDelete
congratulations, sooo sweet.ReplyDelete
adorable! congrats!ReplyDelete
Oh my goodness! Congratulations on the new addition to your family Lisa! He's beautiful!ReplyDelete
xo Ez
Oh, he's sooo sweet! And those tiny little toes.... :)ReplyDelete
HOw adorable, congratulations to your family!ReplyDelete
so precious!! congratulations! xoxoReplyDelete
oooohhhh! Congratulations!!!!ReplyDelete
CONGRATULATIONS!! He is perfect! xoxoReplyDelete
OMG so cute, congrats Lisa! K this is the last of the mass comments for me.ReplyDelete
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text:
After visiting Edible City: A Delicious Journey, make sure to purchase the exhibit's companion book, written by two time James Beard Award winner and exhibit curator, Rebekah Denn. Other fun exhibit-related items are available for any inner culinary connoisseur.
The MOHAI Store is open during all regular museum hours, and does not require admission to the museum to shop. It is located in the Faye G. Allen Grand Atrium, between the Admission Desk and the Microsoft Lakefront Pavilion. Purchases at the Store directly support MOHAI's mission.
Don't forget: MOHAI members receive a 15% discount!


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overview of Mississippi's new open carry law
This is a good explanation of how Mississippi has become an open carry state.
I've been reading some other forums and seems some are pretty worried about how this will go in July.
It should be interesting. Honestly, most people I know have a pistol in their car anyway (legally).
This is a link to a nice MS firearms forum thread by a LEO discussing a LEO-only meeting about the new open carry situation: http://www.msgunowners.com/t41161-open-carry-some-questions-answered-maybe
It was the same in Missouri when they got more carry freedoms. I believe that was when the quote, "the streets will run red with blood" came about.
It's been proven, time and again, crime rates drop so far, everywhere, Americans enjoy more freedoms.
The worry isn't about people being armed. The worry is for a couple of reasons:
1) as a CCW holder in MS now I can tell you that the number of places / businesses that have post posted no firearms signs is pretty low but once open carry goes into effect and it becomes visable I suspect that many more signs will go up in places like chain stores especially but it will happen just in general. This will translate to fewer places I can carry.
2) The initial shock to the system of open carry on the general public is may very well result in more calls to LEOs reporting armed "suspects" wandering about. This will result in more "interaction" which depending on how it is handled by both sides could very well have negative results.
Its a cultural change that if it happens slowly and is handled well will have positive results but it could just as easily go wrong and have very negative results. Hence the worry.
But, the worries being expressed by a lot of people NOT of our culture and by many law enforcement officials, not to mention the legislators who are against it, is that they think crime and gun violence is going to increase. As if just being able to openly carry is suddenly going to lead to high noon shootouts on main street. This has been the big concern among non gun people everywhere that OC has been permitted.
The really funny thing, I think, is that, let's face it, OC isn't popular. OC is legal here, yet only a very small handful of people do it.
I very much suspect it'll be the same in Mississippi.
Orangello, didn't you say you weren't likely to do it either?
Ive open carried for so long now in mississippi, due to being a armed guard it has become second nature to me. Ive open carried in all type of stores and never had a problem, waffle house is a weapons free place although there signage isnt legal.
Evidently we'll have to wait until at least after the 8th. I honestly didn't think Mississippi had any seemingly anti-gun politicians. This however, doesn't prevent permit holders from open carry.
I have wondered if they did that so it wouldn't go into effect during a holiday.
There's a thought. Its effect, though, would be a match on a fire given the actuality of armed marches on the holiday.
Personally Ive never seen anyone open carrying on the streets. I did see a new No Weapons Allowed sign posted in a store in Batesville last Thursday. There might be a few who do OC for a few days, just because they can, but I dont expect much to change. Certainly no blood in the streets! Ha! Thats ridiculous on the face of it.
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Most Helpful Guy
Most Helpful Girl
I just had Chipotle yesterday lol
I typically get a veggie bowl with white rice, lots of fajita veggies, corn, cheese, sour cream, and tomatoes on the side because some Chipotles will have watery tomatoes and I don't like the way the rice absorbs the juice. Occasionally I'll get a chicken taco with fajita veggies, corn, cheese, and sour cream. I rarely ever get burritos anymore.11|00|0
Why don't you like the burrito? My brother the same they get the bowl and most people I ask get the bowl! hahahh I wonder why?
- Show AllShow Less
You're welcome :)
You made me desperately crave Chipotle now ;p
lol hahah so hungry...


text: Weigel's 1210; ca. 1950s; Men's safari jacket. Contents[show] Links to reviews/blog postsEdit Sources/VendorsEdit GalleryEdit WishlistEdit Retrieved from "http://vintagepatterns.wikia.com/wiki/Weigel%27s_1210?oldid=591303" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Vintage Sewing Patterns Weigel's 1940s 1950s Mens Jackets Safari Patch Pockets Shirt-Jackets Notched Collar Front button closing Flaps Topstitching Saddle Stitching Short Sleeves Long Sleeves Yoke Inverted Pleats Belts Madame Weigel's Add category Cancel Save


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Diverse cook, inspired by the Brethren
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Fat Woody
is one Smokin' Farker
Join Date: 03-29-09
Location: Lenexa, Kansas
Here's a few more shots. The back ribs with a liberal dose of Dr. BBQ's Big Time BBQ Rub:
A shot of the old Brinkmann Lefty, loaded:
Pastrami was started with oak and once the butts went on I started mixing in hickory and pecan. For the majority of the cook smoker temps were between 230-250. Everything is off the Lefty now and all turned out well; here's a look at the finished products.
Pastrami - nice peppery crust, looking forward to lots of sammies this weekend:
The two pork roasts, somewhere between slicing and pulling tender, great flavor from the SOW marinade:
Beef ribs - tender and juicy after two and a half hours of smoking and another two hours braising in beer to finish:
Thanks for checking it out!
[B]Head Groundskeeper - Squirrel Haven Estate, Lenexa, KS[/B]
[B][COLOR="Red"]Chief Cook of the infrequently competitive Fullwood Bros' BBQ Team[/COLOR][/B]
[B][COLOR="DarkRed"]Cigar Lounger, Malt Beverage Tester[/COLOR][/B]
Owner/Operator of: Superior "Stealth" SS2, Brinkmann "Lefty" Bandera clone (retired), Comalco Black Dog grill, and various Weber kettles.
World's fastest [B]Belgian/Cuban Racing Yellow[/B] thermapen.
Fat Woody
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Liden & Denz Language Centre
The language school Liden & Denz Language Centre was founded in Riga, Latvia in 2009. Our new center is located on one of the inner street boulevards, right between the main railway station and the National opera. It is located on the second floor of a historical building.
Computer lab
Balcony / terrace
Student support desk
Free water dispenser
Free WIFI
Classroom equipment
TV in most classrooms
Air conditioning in some classrooms
Heating in all classrooms
Ample natural light in all classrooms
Number of classrooms:10
Number of public PC workstations:5
Prices include
- Internet access and use of school computers
- Wireless LAN zone at school
- Free certificate of course attendance
- Language level placement test at first day of classes
- Language level placement test before arrival
Course material:
Average number of students
- Adult courses in summer: 35
- Adult courses throughout the year: 20
Average age of students
- in summer: 30 years
- throughout the year: 30 years
- Special recommendations for students over 30 years
Average number of levels
- Adult courses in summer: 8
- Adult courses throughout the year: 6
Minimum age of students
- 16 years
Russian teacher qualifications
- 100 % hold a university degree
Languages spoken by school staff (cannot be guaranteed by school):
Airport transfer
Best arrival airport is Riga Airport (RIX). It takes 40 minutes to school.
Russian Courses
- Max. 1 student of each nationality possible?yes


text:
|Episode 4125
|Production code
|ITV transmission date
|13th January 1997 (Monday)
|Story editor
|Ann McManus
|Story associates
| Gillian Creswell
David Millard
Matthew Westwood
|Tom Elliott
|Christopher Walker
|Noreen Kershaw
|Sue Pritchard (Uncredited)
|Previous episode
|12th January 1997
|Next episode
|15th January 1997
Andy has moved back in at No.11. Anne tells Curly she's glad Andy has gone and insists he stays, saying she can't manage the mortgage without his help. Samantha is furious when Tricia lords it over her at the Rovers. She tells Jack she'll leave if she doesn't get an apology. Alma is upset to see Mike so low and is short with Gail as she's Stephen's sister. Bill is stunned to discover Andy has left Anne with Curly living in the house. He advises him to separate them and thump Curly. Jim pushes Bill to make things up with Maureen, using her birthday as an excuse. He gives her a plant as a present, pleasing her but she is annoyed by the way Maud tries to push them together. Becky has a crush on Ashley and asks him to sign her new autograph book. Maureen tells Bill she can't help feeling guilty over her fling with Curly. He tells her he's a proud man and it would help him if he believed Curly took advantage of her. She is upset when he tells her Curly's broken up Andy and Anne's relationship. He feels awful when he suggests Curly preferred Anne as she is younger than her. Maureen is hurt by the suggestion. Ken talks to his solicitor about Denise's offer and is advised to agree. Deirdre urges him to grab the settlement and get access in writing. When Alan lets Fiona down over a date Maxine suggests to her that he might be married. Tricia apologises to Samantha. Curly is horrified when Anne gives him a rent book. Alma urges Stephen not to withdraw the contract, for her sake. She is stunned when he tells her she'll never hate him as she's attracted to ruthless men. She runs off when he tells her he knows she'd still love to go to bed with him.
Regular castEdit
- Jim McDonald - Charles Lawson
- Andy McDonald - Nicholas Cochrane
- Bill Webster - Peter Armitage
- Maud Grimes - Elizabeth Bradley
- Curly Watts - Kevin Kennedy
- Anne Malone - Eve Steele
- Mike Baldwin - Johnny Briggs
- Alma Baldwin - Amanda Barrie
- Fiona Middleton - Angela Griffin
- Maxine Heavey - Tracy Shaw
- Samantha Failsworth - Tina Hobley
- Tricia Armstrong - Tracy Brabin
- Jack Duckworth - William Tarmey
- Roy Cropper - David Neilson
- Gail Platt - Helen Worth
- Vera Duckworth - Elizabeth Dawn
- Ken Barlow - William Roache
- Claire Palmer - Maggie Norris
- Maureen Holdsworth - Sherrie Hewson
- Becky Palmer - Emily Aston
- Ashley Peacock - Steven Arnold
- Deirdre Rachid - Anne Kirkbride
Guest castEdit
- Coronation Street exterior
- Rovers Return Inn - Public
- Corner Shop
- Hair by Fiona Middleton
- Jim's Cafe
- No. 4 Montreal House, Weatherfield Quays - Living room/kitchen
- 16 Orchard Close - Living room
- Unnamed hotel
- In place of the producer's credit, a photograph of Jill Summers was presented with the caption Jill Summers: 1910 - 1997 in tribute to the actress who had died two days previously.
- A taxi driver named Sammy by Maud Grimes is uncredited despite having a line of dialogue.
- TV Times synopsis: Curly feels uncomfortable with Anne. Alma pays Stephen Reid a visit.
- Viewing Figures: UK broadcast - 17,660,000 viewers (1st place - combined figure including repeat).
|January 1997 episodes
|Wed 1st • Fri 3rd • Sun 5th • Mon 6th • Wed 8th • Fri 10th • Sun 12th • Mon 13th • Wed 15th
Fri 17th • Sun 19th • Mon 20th • Wed 22nd • Fri 24th • Sun 26th • Mon 27th • Wed 29th • Fri 31st


text:
Peter Lemenkov wrote:
2009/6/11 Oscar Osta Pueyo <oostap listas gmail com>:Hi,* How to enable traditinal ctrl+alt+backpsace behaviour ?http://ryanler.wordpress.com/2009/06/11/controlaltbackspace-shortcut-does-not-restart-the-x-server-in-fedora-11/Unfortunately, I don't use nor Gnome, neither KDE.
If you have an xorg.conf file, or you don't mind creating one, add Option "XkbOptions" "terminate:ctrl_alt_bksp"to the keyboard section. If you don't, you might try using setxkbmap on the command line.


text:
This city apartment hotel features a facade in the purest regional style and comprises a total of 57 air-conditioned apartments. Facilities on offer to guests include a lobby with a 24-hour reception, a breakfast room and WLAN Internet access (for an additional fee). Guests can also take advantage of the laundry service (charges apply).For stays from 1 to 3 nights inclusive (short-stay), a daily housekeeping service is included at the proposed rate. For longer stays, housekeeping is every 7th day, including a change of bed clothes and household linen.The apartments include studio with 2 rooms sleeping 4 people. All come with a private bathroom with a bathtub and a hairdryer. They are equipped with a direct dial telephone and satellite/cable TV with international channels. They have Internet access, a safe and a fully equipped kitchen with a fridge, a microwave and a washing machine. Furthermore, an ironing set, air conditioning and central heating are provided in all accommodation as standard.
Guests arriving by road should take the A4 motorway to Strasbourg. Head for Place de Haguenau, turn right into Rue Bischwiller. Follow the street and continue on Rue du Travail and then Rue de Sebastopol. Take Rue du Noyer before Place Homme de Fer and Place Kl�ber. Those coming on tram lines A, B, C or D, should get off at the Homme de Fer station.


text:
Assalamuwalaikum sister,
My husband and I both practicisng Muslims and are studying in Australia. Due to certain reasons we had a court marriage in Sydney. We plan to have our Islamic wedding ceremony after we return to our home country with out after a year. My question is, can we consummate our marriage under Islamic law or we have to wait till our Islamic Wedding?
I will be really grateful for a kind and helpful reply.
Court Marriage And Sex
Posted 25 November 2016 - 10:57 AM
Assalamuwalaikum sister,
Posted 25 November 2016 - 03:54 PM
Wa 3aliakum assalaam sis. You might find the following 2 links useful:
Hope they answer your query. If it was me, I'd wait to consummate the marriage until the nikkah is conducted.
Posted 20 December 2016 - 06:09 PM
Posted 08 January 2017 - 06:43 PM
Assalamu alaikum I'm elaj single brothers and sisters I have a question I am planning having a baby so it is permissible for me to marry a woman and having a baby and then divorcing her after giving birth?
Wa alaikum assalam
That's not a kind plan brother. Only marry someone if you plan to have a family to cherish and care for. That's what marriage is for.
Posted 30 January 2017 - 10:26 PM
As-Salaam alaikum,
I have noted Sister Nnkhan 1991's post/question above, to which I wish to contribute and/or clarify as follows:--
(1) Any 2 Muslims lovers {man and woman} can marry in any part of the world, provided that they do so in compliance with the
Islamic Shari'a on the subject of marriage.
(2) In Sydney or anywhere, such an event [Muslim marriage] can be formed if:---
(a) The Waliyy (Guardians) of the man... that is the groom and the woman... that is the Bride attend the event/ceremony
and give their consent/formal blessing to the marriage. Of course the guardian of the bride will only do so..give her
(the bride) away in marriage to the groom, only after knowing from the bride of her consent to that effect. And the
Walyy (guardian) of the groom will also have discussed the issue with the groom and his family beforehand.
(b) An agreed dowry is known/mentioned during the ceremony and paid by the groom, through his guardian, to the
Bride, through her guardian.
© The event of the Wedding ceremony is witnessed by at least 2 up-right and/or reliable Muslim adults. The witnesses
to the marriage can be many people, as invited, but should be at least 2 good people.
This is Islamic Wedding, and no marriage is consummated... whereby the bride and the groom have sexual intercourse...until
this is done. Even where a couple is in a foreign land, they should get to an Islamic Madrasa/ Court or an Islamic Head Teacher
where available for assistance in this regards.. to ensure that the above is done before an Islamic marriage is done.
Many Regards.


text:
What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
Cloned forms: receiving emails from other user's that clones my formAsked by SFDCERT on November 22, 2016 at 11:49 AM
We CONTINUALLY get emails from other companies and groups to our email account. HOW is our email address getting into their forms?
We have posted on this forum MANY, MANY times, and no-one is able to fix this.
JotForm - seriously, this is ridiculous. There HAS to be a way to strip email addresses when someone copies one of our forms...I refuse to believe you cannot build that into the process. You KNOW where the email addresses are in the code (...seriously, you can't have it search for "@"?!?!) and it's easy to strip that value out when someone clones one of our forms.
STOP BEING LAZY and causing the form creator to have to deal with angry people who are submitting a form thinking it's going to someone else...STOP making those who submit a form and can't get a resolution...STOP allowing people who copy someone elses form to publish it with incorrect information - causing both them and their customers grief.
JotForm Support
Please accept our sincere apologies for this problem.
You have this form in the Form Template Gallery: https://www.jotform.com/form-templates/uniform-order-form. The form is already deleted in your account as far as I could see it, but the form is still live in the form template gallery. It looks like the form is saved somewhere even though you have deleted that from your account, but I couldn't find it. The form is cloned 3, 645 times.
Note: You can view your list of shared forms using this URL: https://www.jotform.com/form-templates/user/SFDCERT.
When cloning a form, private information such as the email address in the notifiers are automatically replaced with one's primary email. The bug is probably related to the deleted form which is still showing up in the gallery and when cloned, your information is also saved.
We can search for your email address in our system using a wildcard, but that won't help us remove your email address in all forms found in our system. I searched for it, the form has 100 or so copies. This may need a script which only our developers can do.
I'm forwarding this matter to our developers for them to investigate further. We'll let you know as soon as we have it fixed.
Again, our apologies and thank you for creating a new report.


text:
Learn more about PAGG PROPERTIES LIMITED. Check the company's details for free and view the Companies House information, company documents and list of directors.
Know about every new company document that is added!
Take advantage of our watch this company feature free of charge and have notifications sent directly to your inbox. Whenever a new document appears on this website, or if their particulars change, you will be immediately informed about such changes. To monitor these changes, all you need to do is click on watch this company.
|Tangible Fixed Assets
|£ 31,918
|Tangible Fixed Assets Depreciation
|£ 9,966
|Shareholder Funds
|£ 56,043
|Profit Loss Account Reserve
|£ 31,192
|Revaluation Reserve
|£ 24,839
|Called Up Share Capital
|£ 9
|Total Assets Less Current Liabilities
|£ 56,043
|Net Current Assets Liabilities
|£ 24,125
|Creditors Due Within One Year
|£ 4,410
|Cash Bank In Hand
|£ 28,535
|Share Capital Allotted Called Up Paid
|£ 9
|Number Shares Allotted
|£ 12
|Tangible Fixed Assets Cost Or Valuation
|£ 40,784
|Tangible Fixed Assets Depreciation Charged In Period
|£ 1,100
|Capital Redemption Reserve
|£ 3
Information about the Private Limited Company PAGG PROPERTIES LIMITED has been prepared for information purposes only. It is not intended to be nor does it constitute legal advice. This is public information provided by the official company register.


text:
- Latest
- Popular
- Blogs
- Authors
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- Our Blog
Posted by mariahayhow Verner Panton, a design revolutionary, once said, "You sit more comfortably on colours you like." A statement that seems to disregard logic, and focus strictly on the intangible relationships which dictate preferences. So what does this statement say about design, and more importantly, how can YOU apply this to your online marketing strategies? The answ ...


text:
eternally by tetsuok9999Watch
©2012-2017 tetsuok9999
character from Fatal Frame 4.
Misaki & Madoka
Misaki & Madoka
wow nice
Beautiful and lovely, i love the colors, nice work, it looks so cute, i love them. You are awesome doing this work!!!!!!
This is just gorgeous! Excellent work! <3
This is beautiful! i really love this!
*im still playing this game lol
*im still playing this game lol
Thank you so much!!
I have not been released outside of Japan is ff4 is really regrettable.
I have not been released outside of Japan is ff4 is really regrettable.
Oh my goodness, absolutely gorgeous. This is incredible! I love the muted colors, the way you made Madoka glow, and the peaceful expression on Misaki's face. Fantastic.
So beautiful! Very nice
The spirit girl seems a little too bright, but I love the character poses. Nice work.
cool i see this on pixv^^
Oh, this is amazing !
Looks beautiful! Great job~
so pretty
i love them both so much >/////<
i love them both so much >/////<
So beautiful!
This is both stunning and beautiful. And I love the characters. Awesome work.


text:
BillerudKorsnäs' sale of its shares in the Baltic pellets operations SIA Latgran is now completed, as the company says in the press release received by Lesprom Network.
BillerudKorsnäs' ownership in Latgran was 75%, and the remaining 25% was owned by Baltic Resources Ab. The total consideration for 100% of the Company amounted to Euro 104 million on a cash and debt free basis, corresponding to a multiple of 7x Latgran's EBITDA for 2014.
BillerudKorsnäs provides packaging materials and solutions that challenge conventional packaging for a sustainable future.


text:
Each month, Rated People connects over 50,000 homeowners with quality tradesmen - simply enter your job details in the form above to get started.
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Window fitter / Conservatory installer
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Services required: Find and repair a leak There is a hole in the felting and sometimes a little...
Managing your job is easier with the Rated People Homes App, download it today.


text:
|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|"David Weintraub" <qazw...@gmail.com>
|Subversion Ant Tasks
|Mon, 28 Jul 2008 22:23:33 GMT
I'm having some difficulties with Subversion's Ant tasks. I am on SUSE 9.0 which has the latest Subversion release of 1.3. However, I am building with Hudson that is using svnkit which is using a release 1.4.6 revision. The problem is I build with Hudson, it creates a 1.4.6 compatible workspace, then I attempt to do something in my Ant file, and I get the message that my Subverison client is too old. I went to subclipse and got the svnant task. This includes a svnant.jar and a svnClientAdapter.jar. Apparently, the svnjavahl.jar I am using is a 1.3 client version. According to the documentation, svnClientAdapter.jar can use the svnjavahl, the svnkit, or the command line. I've removed the "svn" command from my path, and setup the following build.xml: <project name="test" default="test" basedir="."> <!-- Subversion Setup --> <path id="svn.task.path"> <pathelement location="${ant.home}/lib-svn/svnant.jar"/> <pathelement location="${ant.home}/lib-svn/svnClientAdapter.jar"/> <pathelement location="${ant.home}/lib-svn/svnkit-javahl.jar"/> </path> <taskdef resource="svntask.properties" classpathref="svn.task.path"/> <property file="${user.home}/.subversion/svn.properties"/> <!-- User Name & Pword --> <target name="test"> <svn javahl="true" username="svnant" password="SNVant123"> <cat url="http://subversion.solbright.com/dev/modules/foundation/trunk/build.xml" destfile="foo.xml"/> </svn> </target> </project> I get the following errors: Buildfile: build.xml test: BUILD FAILED /solbright/tools/build/build.xml:18: Cannot use javahl nor command line svn client I have tried modifying the file to use svnjavahl.jar, but get the same error. It only works if I put the svn command back into the PATH, so it can execute via the svn command line. Unfortunately, that's 1.3, and I need a 1.4.6 compatible client. Has anyone else used the Subversion tasks in Ant? Any help in configuring them? -- David Weintraub email@example.com --------------------------------------------------------------------- To unsubscribe, e-mail: firstname.lastname@example.com For additional commands, e-mail: email@example.com
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text:
Before books, students had to tote engraved granite slabs all over campus, which is why the most accomplished philosophers gave the best piggyback rides. Enjoy lighter reading material with today's Groupon: for $12, you get $25 worth of New Age books and gifts at Heaven On Earth Books & Gift Shop in Southington.
Committed to holistic health and Connecticut's thriving community of artists and merchants, Shirley Bloethe of Heaven On Earth lines her shelves with New Age tomes and related trade goods. Bookworms can sit a spell in a comfy chair, flipping through informative texts on massage and therapeutic modalities such as Jeanne Rose's The Aromatherapy Book ($18.95), or Total Reflexology by Dr. Martine Faure-Alderson ($19.95), whose toe-tickling treatments affect the whole body instead of just the giggle-plexus.
Tarot and angel cards may shine a light on higher meaning, and yoga paraphernalia, such as DVDs and mats ($12), facilitates healthy home practices. Locally made gifts might include sea-glass jewelry ($15–$20), all-natural bath soaps ($4–$5), and sweet-scented soy candles ($6–$10). Nontoxic cleaning agents help keep abodes pristine by preventing grimy buildup from soiled karmic auras, and all-natural health and wellness supplements can provide Earth-friendly weight-loss solutions far less stringent than an acorn-only diet.


text:
An auction catalog offered a "rare Kakiemon enameled porcelain plate" from the 18th century, but there was no further explanation of the age, history or design. What is the meaning of Kakiemon? Sakaida Kakiemon (1596-1666) was a potter who worked in Japan in the early 17th century.
Current subscribers have full access to all online news content as part of their subscription. If you are a current subscriber, please log in with your website account information for full access. If you are a current subscriber, but have not yet registered for access to the website, please call our Circulation Department at 740-439-3531


text:
Tracking Iowa Meth Lab Incidents 201 Reported to DNE for 2008 (as of 01-31-09) Totals for 2007 - 178 Totals for 2006 - 345. (*SF 169—pseudoephedrine control—signed into law 3-22-05, effective 5-21-05 ).
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
(*SF 169—pseudoephedrine control—signed into law 3-22-05, effective 5-21-05)


text:
"Rebranding has been a goal of ours for the past four or so years, and up until we met with CRP it was a daunting, confusing task. Any good organization is the sum of its parts, or better said, its people. Partnering with CRP has helped to better define who we are – both visually and verbally – which in turn helps us grow our mission to help families in our community."Mateo Messina
"Working with CRP has been flawless in design, process and delivery. They are without a doubt, a loved and integral part of our brand and company. CRP has listened intently to my aesthetic design goals, and together we have gone down many paths where ultimately, they were able to harmoniously unite 'earthy' and 'high end' into a brand that guests respond to in the way I set out to do."AUTUMN MARTIN
"From a project management perspective, my experience working with CRP has been professional, courteous, on-schedule, and efficient. They are able to take complex direction and deliver creative results under compressed retail timelines, which is a very hard thing to find in the design agency world. They have become almost like an extension of our internal team at Sur La Table, and are a reliable, trustworthy partner on any special project."Karen Keller
"CRP has been a critical partner in the development and execution of the Kalla brand. The entire team has been wonderful to work with and committed to finding solutions to difficult challenges. Their dedication, from the conception of the brand, has been impressive and truly appreciated. Our packaging is obviously an essential part of our brand experience, and their expertise in this field has been crucial to the evolution and success of Kalla."Hani Yassin
"When I first visited CRP, I knew I had a product with potential. After meeting with them, I realized that potential was even greater than I imagined. I wanted Simple & Crisp to be something that people are proud to buy and serve—so much so, that they would feel comfortable putting the package on their table as they entertained. The process of taking the dielines CRP had drawn and making prototypes out of them played a vital role in solving the packaging challenges I faced. The crisps look beautiful in the packaging, and I am very pleased with the end result."Jane Yuan
"Working with CRP was a breath of fresh air for us. Not only did we feel our design aesthetics and desires were heard, the team led us through multiple design phases that made sure we were confident with our choices and progress. It made a largely complicated and overwhelming project run smoothly, and we felt confident in the hands of our CRP designers."Jeannie Liu


text:
Citations for "Mean-Variance Preferences and Investor Behaviour"
by Ormiston, Michael B & Schlee, Edward E
- Thomas Eichner & Andreas Wagener, 2004. "Relative risk aversion, relative prudence and comparative statics under uncertainty: The case of (μ, σ)-preferences," Bulletin of Economic Research, Wiley Blackwell, vol. 56(2), pages 159-170, 04.
- Gollier Christian & Schlee Edward E, 2006.
"Increased Risk-Bearing with Background Risk,"
The B.E. Journal of Theoretical Economics,
De Gruyter, vol. 6(1), pages 1-29, March.
- Edward Schlee & Christian Gollier, "undated". "Increased Risk-Bearing with Background Risk," Working Papers 2132848, Department of Economics, W. P. Carey School of Business, Arizona State University.
- G. Boyle & D. Conniffe, 2005. "When does 'All Eggs in One Risky Basket' Make Sense?," Economics, Finance and Accounting Department Working Paper Series n1550305, Department of Economics, Finance and Accounting, National University of Ireland - Maynooth.
- Thomas Eichner & Andreas Wagener, 2011. "Portfolio allocation and asset demand with mean-variance preferences," Theory and Decision, Springer, vol. 70(2), pages 179-193, February.
- Bilancini, Ennio & D'Antoni, Massimo, 2012. "The desirability of pay-as-you-go pensions when relative consumption matters and returns are stochastic," Economics Letters, Elsevier, vol. 117(2), pages 418-422.
- Aivaliotis, Georgios & Palczewski, Jan, 2014. "Investment strategies and compensation of a mean–variance optimizing fund manager," European Journal of Operational Research, Elsevier, vol. 234(2), pages 561-570.
- Broll, Udo & Wahl, Jack E. & Wong, Wing-Keung, 2006. "Elasticity of risk aversion and international trade," Economics Letters, Elsevier, vol. 92(1), pages 126-130, July.
- Udo Broll & Jack E. Wahl & Wing-Keung Wong, 2005. "Elasticity of risk aversion and international trade," Monash Economics Working Papers 07/05, Monash University, Department of Economics.
- Udo Broll & Jack E. Wahl & Wing-Keung Wong, 2005. "Elasticity of risk aversion and international trade," Departmental Working Papers wp0510, National University of Singapore, Department of Economics.
- Broll, Udo & Guo, Xu & Welzel, Peter & Wong, Wing-Keung, 2015. "The banking firm and risk taking in a two-moment decision model," Economic Modelling, Elsevier, vol. 50(C), pages 275-280.
- Schlee, Edward & Chade, Hector, 2012. "Optimal insurance with adverse selection," Theoretical Economics, Econometric Society, vol. 7(3), September.
- Hector Chade & Edward Schlee, 2008. "Optimal Insurance with Adverse Selection," Levine's Working Paper Archive 122247000000002175, David K. Levine.
- repec:ebl:ecbull:v:6:y:2004:i:5:p:1-7 is not listed on IDEAS
- Eichner, Thomas & Wagener, Andreas, 2014. "Insurance demand and first-order risk increases under (μ,σ)-preferences revisited," Finance Research Letters, Elsevier, vol. 11(4), pages 326-331.
- Petr Havlik & Geoffroy Enjolras & Jean-Marie Boisson & Florence Jacquet & Michel Lherm & Patrick Veysset, 2008. "Environmental good production in the optimum activities portfolio of a risk averse-farmer," Review of Agricultural and Environmental Studies - Revue d'Etudes en Agriculture et Environnement, INRA Department of Economics, vol. 86(1), pages 9-33.
- Havlik, Petr & Jacquet, Florence & Boisson, Jean-Marie & Veysset, Patrick & Lherm, Michel, 2005. "Environmental Good Production in the Optimum Activities Portfolio of a Risk Averse Farmer," 2005 International Congress, August 23-27, 2005, Copenhagen, Denmark 24594, European Association of Agricultural Economists.
- Thomas Eichner, 2008. "Mean Variance Vulnerability," Management Science, INFORMS, vol. 54(3), pages 586-593, March.
- Thomas Eichner & Daniel Weinreich, 2015. "Welfare stigma and risk taking in the welfare state," Social Choice and Welfare, Springer;The Society for Social Choice and Welfare, vol. 44(2), pages 319-348, February.
- Broll, Udo & Wong, Wing-Keung & Wu, Mojia, 2013. "Banking Firm and Two-Moment Decision Making," MPRA Paper 51687, University Library of Munich, Germany.
- Trino-Manuel Niguez & Ivan Paya & David Peel & Javier Perote, 2013. "Higher-order moments in the theory of diversification and portfolio composition," Working Papers 18297128, Lancaster University Management School, Economics Department.
- Udo Broll & Jack E. Wahl, 2004. "Optimal hedge ratio and elasticity of risk aversion," Economics Bulletin, AccessEcon, vol. 6(5), pages 1-7.
- Chambers, Robert G. & Grant, Simon & Polak, Ben & Quiggin, John, 2014. "A two-parameter model of dispersion aversion," Journal of Economic Theory, Elsevier, vol. 150(C), pages 611-641.
- Chambers, Robert G. & Grant, Simon & Polak, Ben & Quiggin, John, 2011. "A Two-Parameter Model of Dispersion Aversion," Risk and Sustainable Management Group Working Papers 151196, University of Queensland, School of Economics.
- De Pinto, Alessandro & Robertson, Richard D. & Obiri, Beatrice Darko, 2013. "Adoption of climate change mitigation practices by risk-averse farmers in the Ashanti Region, Ghana," Ecological Economics, Elsevier, vol. 86(C), pages 47-54.
- Broll, Udo & Gilroy, Bernard Michael & Wahl, Jack E., 2003. "Information, unternehmensinterne Kommunikation und Risikopolitik
[Information, intra-firm communication and risk policy]," MPRA Paper 21731, University Library of Munich, Germany.
- Broll, Udo & Gilroy, B. Michael & Wahl, Jack E., 2003. "Information, unternehmensinterne Kommunikation und Risikopolitik," Dresden Discussion Paper Series in Economics 06/03, Technische Universität Dresden, Faculty of Business and Economics, Department of Economics.
- Eichner, Thomas & Wagener, Andreas, 2012. "Tempering effects of (dependent) background risks: A mean-variance analysis of portfolio selection," Journal of Mathematical Economics, Elsevier, vol. 48(6), pages 422-430.
- Broll, Udo & Egozcue, Martín & Wong, Wing-Keung, 2009. "Prospect theory and two moment model: the firm under price uncertainty," Dresden Discussion Paper Series in Economics 01/09, Technische Universität Dresden, Faculty of Business and Economics, Department of Economics.
- Guo, Xu & Wagener, Andreas & Wong, Wing-Keung & Zhu, Lixing, 2017. "The Two-Moment Decision Model with Additive Risks," MPRA Paper 77625, University Library of Munich, Germany.
- Alghalith, Moawia & Guo, Xu & Wong, Wing-Keung & Zhu, Lixing, 2013. "Input Demand under Joint Energy and Output Prices Uncertainties," MPRA Paper 52368, University Library of Munich, Germany.
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