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AIDS Trestment News
A Call for More Cautious Antiretroviral Treatmentby John S. James
For example, Dr. Henry describes the enormous benefit of modern antiretrovirals: "Deaths in our HIV population decreased 85% in a 1-year period" when protease inhibitor-based therapy was introduced. But he also notes that hope for eradication, "perhaps more than any other assumption ... powered enthusiasm for immediately beginning treatment." With eradication not currently possible, he urges a new evaluation of risks and benefits of aggressive vs. conservative antiretroviral treatment.
"Early, aggressive therapy often prematurely exposes patients to risks for medication-related side effects and resistance. A more cautious, patient-focused, long-term approach to therapy would help foster studies of alternative strategies, such as delayed initiation of therapy, protease-sparing therapy, class-sparing therapy, planned drug interruptions, switches in therapy, and immune-based therapy. It is time for clinicians to rethink their approach to the treatment of HIV infection."
Dr. Henry also discusses the financial incentives that direct research toward short-term studies of particular drugs in treatment-naive patients, for example, when most patients are treatment-experienced, and long-term treatment strategy studies are needed. "It is frustrating that an increasing number of clinical studies focus more on what is good for the drug than on what is good for the patient. Little attention is paid to reasonable salvage regimens or use of regimens that involve drugs from different companies."
And Dr. Henry calls for more support for the clinic that are necessary if patients' medical care, including the difficult drug regimens, is to be properly managed. "The key role of HIV specialists, nurses, case managers and pharmacists is not emphasized enough so that support for the need to supervise the difficult use of these new drugs is often lacking. In today's setting, the most important person involved in the process is the one who answers a question, helps with a medication schedule, or adds insight into care."
The article, with a link to the accompanying editorial, is available online to anyone (you do not need to subscribe to the journal) at: http://www.acponline.org./journals/annals/15feb00/henry.htm.
St. John's Wort Warning: Do Not Combine with Protease Inhibitors, NNRTIsby John S. James
So far, St. John's wort has only been tested for interaction with the protease inhibitor indinavir (Crixivan®). However, this kind of drug interaction is well known, and it is believed that the problem is also likely to affect other protease inhibitors, and possibly also non-nucleoside reverse transcriptase inhibitors (for example, efavirenz and nevirapine). Since modern antiretroviral treatment in the U.S. usually uses at least one drug from one of these classes, the practical consequence is that St. John's wort should not be taken concurrently with antiretroviral treatment.
The new warning followed a study(1) carried out at the U.S. National Institutes of Health, and published in The Lancet on February 12. HIV-negative volunteers took standard doses of indinavir for one day, then took one dose on the second day -- after which blood plasma levels of indinavir were measured. Then they took St. John's wort (a preparation with standardized hypericin content was used) for two weeks -- and while continuing the St. John's wort, repeated the indinavir dosing and blood plasma level measurements. The effect on indinavir levels was seen by comparing the two measurements -- without St. John's wort, vs. with.
The overall blood levels were decreased by an average of 57% when St. John's wort was being used. And the critical trough levels -- the lowest levels, just before the next dose of indinavir 8 hours later -- were estimated to decrease by 80% (this decrease was estimated instead of measured, because only 5 hours, not 8 hours, of blood measurements were taken).
More information about the study (even more than in the published article) is available at www.thelancet.com but subscription or registration is necessary. Also, the February 12 issue has a report of two cases of organ transplant rejection which appear to have been caused by reduced cyclosporine levels due to St. John's wort -- and several letters discussing pros and cons of St. John's wort, which does have mainstream medical support for use as an antidepressant. (One letter notes that the herbal product contains many potentially active chemicals, and it is not known whether the active ingredient that may work as an antidepressant is the same ingredient that causes the drug interactions -- meaning that it might be possible to develop a formulation that separates the two effects.)
Nothing in the new findings suggests any problem with St. John's wort itself, except for patients who are taking medications with which it may interact.
The FDA sent the following advisory this month:
"FDA Advisory, February 10, 2000
"Risk of Drug Interactions with St. John's Wort and Indinavir and Other Drugs
"Dear Health Care Professional:
"The Food and Drug Administration would like to inform you about results from a study conducted by The National Institutes of Health (NIH) that showed a significant drug interaction between St John's wort (Hypericum perforatum), an herbal product sold as a dietary supplement, and indinavir, a protease inhibitor used to treat HIV infection. In this study, concomitant administration of St. John's wort and indinavir substantially decreased indinavir plasma concentrations, potentially due to induction of the cytochrome P450 metabolic pathway. For additional information on this study, please refer to the February 12, 2000 Lancet publication (Piscitelli, et al).
"Indinavir and other antiretroviral agents
"At this time, pharmacokinetic data are available only for concomitant administration of indinavir with St. John's wort. However, based on these results, it is expected that St John's wort may significantly decrease blood concentrations of all of the currently marketed HIV protease inhibitors (PIs) and possibly other drugs (to varying degrees) that are similarly metabolized, including the non-nucleoside reverse transcriptase inhibitors (NNRTIs). Consequently, concomitant use of St John's wort with PIs or NNRTIs is not recommended because this may result in suboptimal antiretroviral drug concentrations, leading to loss of virologic response and development of resistance or class cross-resistance.
"Because herbal products are widely used in the United States and are available in various forms such as combination products and teas, it is important that health care professionals ask patients about concomitant use of products that could contain St. John's wort (Hypericum perforatum).
"In addition, FDA is working closely with drug manufacturers to ensure that product labeling of antiretrovirals is revised to highlight the potential for drug interactions with St. John's wort.
"Other drugs
"Based on this study and reports in the medical literature, St. John's wort appears to be an inducer of an important metabolic pathway, cytochrome P450. As many prescription drugs used to treat conditions such as heart disease, depression, seizures, certain cancers or to prevent conditions such as transplant rejection or pregnancy (oral contraceptives) are metabolized via this pathway, health care providers should alert patients about these potential drug interactions to prevent loss of therapeutic effect of any drug metabolized via the cytochrome P450 pathway.
"All health care professionals are encouraged to report any serious adverse event associated with the concomitant use of prescription drugs and St. John's wort products to the FDA's MedWatch program at 1-800-FDA-1088 (fax 1-800-FDA-0178)."
New Guidelines for HIV Treatment; Resistance Testing Now Recommended
"This report recommends that care should be supervised by an expert, and makes recommendations for laboratory monitoring including plasma HIV RNA, CD4+ T-cell counts and HIV drug-resistance testing. The report also provides guidelines for antiretroviral therapy, including when to start treatment, what drugs to initiate, when to change therapy, and therapeutic options when changing therapy. Special considerations are provided for adolescents and pregnant women. As with treatment of other chronic conditions, therapeutic decisions require a mutual understanding between the patient and the health care provider regarding the benefits and risks of treatment. Antiretroviral regimens are complex, have major side effects, pose difficulty with adherence, and carry serious potential consequences from the development of viral resistance due to non-adherence to the drug regimen or suboptimal levels of antiretroviral agents. Patient education and involvement in therapeutic decisions is important for all medical conditions, but is considered especially critical for HIV infection and its treatment."[from the Summary, page 2]
A major change in these guidelines is that viral resistance testing is recommended -- in case of virologic failure during antiretroviral therapy, or of less than optimal suppression of viral load after starting therapy. Resistance testing should also be considered in acute HIV infection (but treatment should begin immediately, not wait for the results of the test).
But resistance testing is not generally recommended before starting treatment of chronic infection -- or after discontinuation of antiretroviral drugs -- because when the drugs are absent, the resistant virus is likely to become a minor species that is missed by the test but ready to come back quickly when the drugs are started again. Also, resistance testing is not recommended when viral load is under 1,000 copies/mL, because current tests are unreliable when the viral load is very low.
These guidelines (which are 100 pages of text, including the tables and references) were developed by a panel of experts convened by the U.S. Department of Health and Human Services, and the Henry J. Kaiser Family Foundation. There is a list of major changes, showing where this version differs from the previous one.
Note: Similar but not identical HIV treatment guidelines, from a different panel (convened by the International AIDS Society-USA), were published January 19 in JAMA, (Journal of the American Medical Association). They are available at http://jama.ama-assn.org/issues/v283n3/full/jst90023.html.
HIV Resistance-Testing Information on Web
A Web site for physicians provides brief articles on resistance testing, ask-the-experts questions and answers, tables showing which mutations affect which drugs, a glossary, and other background information. "Designed to deliver important new research findings to the practicing clinician, each feature article contains pertinent background information and an emphasis on practical implications." Next month, a review of drug-resistance information from the recent Retroviruses conference will be added.
Article topics include new drugs in development, changing FDA requirements for approval of new resistance tests and of new drugs, and reports from the 3rd International Workshop on HIV Drug Resistance, San Diego, 1999. See especially the Best of Site page.
This site is funded through the UCLA Clinical AIDS Research and Education (CARE) Center, and is made possible by an unrestricted educational grant from Roche Pharmaceuticals. It is available at: http://www.hivresistance.com.
Abacavir Warning: Certain Respiratory Symptoms Can Indicate Hypersensitivity Reaction
This risk of hypersensitivity to abacavir has long been known. But recently the FDA and Glaxo Wellcome changed the warning in the official labeling to point out that respiratory symptoms may be part of the hypersensitivity reaction. Shortness of breath has always been in the description; now cough and sore throat have been added. This is because some cases of hypersensitivity to abacavir were initially diagnosed as pneumonia, bronchitis, or respiratory tract illness.
Patients using abacavir who suspect they may have the hypersensitivity reaction need to contact their physician immediately. If this reaction occurs, the drug must be stopped. But the cost of stopping unnecessarily because of a false diagnosis of hypersensitivity reaction is that an important option will be lost. Therefore, when patients have symptoms suggestive of a hypersensitivity reaction, a careful evaluation by the health care provider is important.
Below is the January, 2000 letter sent by Glaxo Wellcome to health care professionals, warning them of the need to consider certain respiratory symptoms along with other symptoms in evaluating a patient for the diagnosis of hypersensitivity to abacavir.
Also, the complete labeling for the drug, including the new information about the hypersensitivity reaction, is available at: http://www.glaxowellcome.com/pi/ziagen.pdf.
"Letter to Health Care Professionals GlaxoWellcome January 2000
"Important Drug Warning
"Re: Fatal Hypersensitivity Reactions, Respiratory Symptoms, and Ziagen® (abacavir sulfate)
"Dear Health Care Provider:
"Glaxo Wellcome Inc. would like to bring to your attention a revised Warning in the labeling for Ziagen (abacavir sulfate) about fatal hypersensitivity reactions to abacavir in patients presenting with respiratory symptoms. Ziagen is a nucleoside analogue reverse transcriptase inhibitor indicated for use in combination with other antiretroviral drugs for the treatment of HIV-1 infection.
"Since its approval in December 1998, the labeling for Ziagen has included a Warning and description of fatal hypersensitivity reactions to Ziagen. Although presentations vary markedly between patients, frequently occurring features of these hypersensitivity reactions are fever, rash, gastrointestinal symptoms (nausea, vomiting, diarrhea, or abdominal pain), and fatigue or malaise. While respiratory symptoms have been recognized as part of the hypersensitivity reaction in some patients, recent information underscores their importance.
"Fatalities in patients treated with Ziagen who developed hypersensitivity reactions in which the initial presentation included respiratory symptoms of dyspnea, cough, or pharyngitis have been reported. Deaths have been reported in patients receiving Ziagen who were initially diagnosed with an acute respiratory disease (pneumonia, bronchitis, or flu-like illness) and who were later recognized to have had a hypersensitivity reaction to abacavir that included respiratory symptoms. A delay in diagnosis of hypersensitivity can result in Ziagen being continued or re-introduced, leading to more severe hypersensitivity reactions, including life-threatening hypotension and death.
"Review of reports of hypersensitivity in patients receiving Ziagen indicates that respiratory symptoms (including cough, dyspnea, and pharyngitis) have occurred in approximately 20% of patients who have had hypersensitivity reactions. In contrast to some allergic reactions, wheezing or bronchospasm have occurred only infrequently in patients with hypersensitivity reactions to Ziagen.
"The diagnosis of hypersensitivity reaction should be carefully considered for patients presenting with symptoms of acute respiratory diseases and other symptoms associated with hypersensitivity to abacavir, even if alternative respiratory diagnoses (pneumonia, bronchitis, pharyngitis, or flu-like illness) are possible. If the clinical presentation of an acute illness cannot be clearly differentiated from a hypersensitivity reaction, Ziagen must be permanently discontinued. Ziagen should not be restarted following a hypersensitivity reaction because more severe symptoms will recur within hours and may include life-threatening hypotension and death.
"This updated warning about fatal hypersensitivity reactions to abacavir in patients presenting with respiratory symptoms is now included in the revised labeling for Ziagen. In addition, this revised warning is reflected in the Patient Medication Guide and Warning Card and should be discussed with patients treated with Ziagen.
"This information is provided to help you in the management of patients prescribed Ziagen Tablets or Ziagen Oral Solution. Please take the time to read the enclosed revised package insert, including the revised warning below (in bold), for additional product information and other risks associated with the recommended use of Ziagen.
"Fatal hypersensitivity reactions have been associated with therapy with Ziagen. Patients developing signs or symptoms of hypersensitivity (which include fever; skin rash; fatigue; gastrointestinal symptoms such as nausea, vomiting, diarrhea, or abdominal pain; and respiratory symptoms such as pharyngitis, dyspnea, or cough) should discontinue Ziagen as soon as hypersensitivity reaction is suspected. Ziagen should not be restarted following a hypersensitivity reaction because more severe symptoms will recur within hours and may include life-threatening hypotension and death (see Warnings, precautions: Information for Patients, and Adverse Reactions).
"Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues alone or in combination, including Ziagen and other antiretrovirals (see Warnings).
"Ziagen in combination with other antiretroviral agents is indicated for the treatment of HIV-1 infection. This indication is based on analyses of surrogate markers in controlled studies of up to 24 weeks in duration. At present, there are no results from controlled trials evaluating long-term suppression of HIV RNA or disease progression with Ziagen.
"Although hypersensitivity reaction is described in the package insert for Ziagen, you can assist us in continuing to monitor the safety of Ziagen products by reporting all cases of hypersensitivity reaction occurring in patients treated with Ziagen to the Abacavir Hypersensitivity Reaction Registry at Glaxo Wellcome at 1-800-270-0425 or to the FDA MedWatch program by telephone at 1-800-FDA-1088, via fax at 1-800-FDA-0178, or by mail at MedWatch HF-2, FDA, 5600 Fishers Lane, Rockville, MD 20857.
"We appreciate the opportunity to provide this information to facilitate the care of your patients. Any questions from health care professionals may be directed to our Drug Information Department at 1-800-334-0089. Thank you."
Copyright 2000 by John S. James. Permission granted for noncommercial reproduction, provided that our address and phone number are included if more than short quotations are used.


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Gracyanne Barbosa – Babe of the Day
The Babe of the Day for today is Gracyanne Barbosa, a hard-bodied hottie from Brazil.
If you're like us, then checking out Miss Barbosa has got you wanting to get tickets to head down south and spend some quality time in Brazil. The 30-year-old model, actress and dancer has one of the best physiques we've seen and is probably strong enough to show any of us up in a feat of strength.
Follow her on Facebook and Instagram to see more pictures of Gracyanne and her amazing body.

subset: commoncrawl


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Game Developer Magazine's 15th Annual Front Line Awards 2012
January 18, 2013 Page 1 of 4
A reprint from the January 2013 issue of Gamaustra's sister publication Game Developer magazine, this annual feature gives awards to the best tools for developers. You can subscribe to the print or digital edition at GDMag's subscription page, download the Game Developer iOS app to subscribe or buy individual issues from your iOS device, or purchase individual digital issues from our store.
For 15 years, we at Game Developer have continued to honor the best development tools in the business with our Front Line Awards. Here's how it works: We started with an open nomination process where readers and at-large community members could nominate their favorite tools. From there, the Game Developer and Gamasutra editors, with a little help from our respective advisory boards, sorted through those nominations to come up with a list of finalists that we put to a community vote to determine which tools come out on top.
This year's crop of Front Line Award winners includes a few repeat winners and a few new members to the club, which is not so surprising, considering how our industry somehow manages to simultaneously change and yet stay the same. Havok Physics, Pro Tools, and Unreal Engine 3 had repeat wins this year, while Luxology's modo 601 managed to unseat Autodesk 3ds Max for best Art tool, and Bugzilla finally won a much-deserved nod in the Programming category.
Also, we nixed the Networking category in favor of a Best Free Tool category; as more and more game developers start working in small and scrappy indie studios, it becomes ever more important for devs to make sure they can work with tools that don't break their (nonexistent) budgets.
Congratulations to the winners! Here's to another year of great games -- and the tools to build them with.
- Patrick Miller
Hall of Fame
Unity 3D
Unity Technologies
In the late 2000s the game industry planted the seeds of change. High-quality development tools, historically hidden behind high-cost barriers, were being opened up to the masses for free or cheap. Along with this democratization of tools came an increased focus on speed and ease of development. Fast-forward to 2012: Tools across the board are easier to obtain and use, which has enabled the indie sector's rise to prominence, and one of the most important tools to come out of this era is Unity. Out of this storm of experimentation, Unity bubbled to the top, offering an unprecedented mix of power, value, and ease of use that has put new faces in the game development scene while simultaneously offering established developers a compelling tool.
Speed of development is a key factor in making games, and this is arguably Unity's strongest suit. Coding for Unity is simply a nice experience; it has a clean, component-based architecture that is both powerful and flexible. Since it's built on Mono, those who've had run-ins with .NET will be partly familiar with it, while its JavaScript support eases the transition for web developers. The code side of things meshes well with the Unity Editor, which provides many of the commonly used development tools (level editing, asset importing, animation tool, particle designer, and so on).
Unity also has a lot of power in the non-coding tools, and very few barriers to getting your hands dirty when you need coding support; the whole package plays nicely together. This is a powerful combination that allows you to fluidly move between using code-based solutions and tool-based solutions without struggling against Unity. The editor itself can be modified through code, allowing you to tailor your own tools, which is a boon if you need to provide extra support for non-coders that integrates with the rest of Unity. The broad deployment options that Unity provides are also a big time saver if you're interested in cross-platform releases, or if you need to standardize engineers with disparate skills onto one toolset.
Unity's potential for speedy development makes it particularly useful for small studios and indies, especially because it offers a free basic license and reasonable pricing for its pro and platform licenses. I worked at a small iOS independent studio on a game called Grem Legends, and one of the engineers didn't know native code -- but we needed all hands on deck. We were all pretty well-versed in C#, had a little bit of Unity experience, and didn't have time to build a bunch of tools from scratch, so we chose Unity. With Unity we got the game done on a tight schedule, which would have been tough if we had taken a different production path.
Once I got comfortable using Unity, I started using it as my standard tool for game jams as well. I used it at the "What Would Molydeux?" jam, and was able to finish the game coding solo while still going home and getting some sleep each night.
We would be remiss if we didn't acknowledge that part of what makes Unity special is the community of Unity devs. There are a lot of people using Unity, which means it's easy to share knowledge with and support other devs. The Unity team also provides the community with the Asset Store, which allows developers to distribute plug-ins that they've created. Beyond providing a means for developers to sell their tools, it's a centralized repository of tools, making hunting for what you need not quite as painful.
Unity is still a generalized engine, which means compromises that keep it from being a cutting-edge tool, but for many developers the tradeoff is well worth it. Plus, it abstracts away much of the extremely technical work involved in reasonably efficient rendering, opening the gate of development to those who aren't Direct3D/OpenGL gurus. For studios operating on the bleeding edge, or who need different workflows than what Unity has to offer, it can still be valuable for quickly prototyping, iterating ideas, and tinkering.
Unity reflects the change that has been occurring for the past several years in the industry. It's approachable, both from a financial and technical perspective, and offers excellent results for the amount of effort you put into it. What's more, Unity thrives in the diverse ecosystem of devices that game developers need to address, and with its swift development speed, it can have a place in all manner of studios, from the four-person team at a game jam to the triple-A juggernauts. Unity has opened the doors of game development for many, and we wouldn't have some great games without it.
Elijah O'Rear is a software engineer at Midverse Studios.
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Israel News - Stay Informed, Pray Informed
Amr Moussa, the current frontrunner in Egypt's first presidential election campaign since the fall of former dictator Hosni Mubarak, said on Monday that Egypt's peace treaty with Israel was only ever about birthing a Palestinian state, and is now "dead."
Speaking to voters in southern Egypt, Moussa declared, "The Camp David agreements do not exist anymore. They are an historic document whose place is now on the shelf. The purpose of the agreement with Israel was to establish an independent Palestinian state."
Moussa stressed that did not mean that as president he would cancel the peace treaty with Israel. Rather, he insisted that Israel-Egypt relations are now governed by the 2002 Saudi-authored Arab League peace proposal, which promises Israel peace with its neighbors in exchange for meeting all Arab land demands.
In other words, if Israel adequately complies with demands that it surrender Judea, Samaria and the entire eastern half of Jerusalem, Egypt will maintain the cold peace that has existed between the two nations since 1979.
As one of the few candidates not affiliated with the Muslim Brotherhood or another of Egypt's Islamist factions, Moussa is seen as a "moderate" leader and a desirable counter-balance to Muslim Brotherhood control of the parliament.
However, during his previous stints as Egypt's foreign minister and secretary-general of the Arab League, Moussa has made it clear that harbors no love for the Jewish state, and sees the Camp David Accords as little more than an agreement of convenience. His latest remarks would seem to reinforce that assessment.
A poll published this week by the Al-Ahram Center for Political Studies predicted Moussa winning 41.1 percent of the vote when Egyptians go to the polls later this month. His closest challenger is Abdel-Moneim Abolfotoh, a former Muslim Brotherhood leader who after leaving the group has gained broad support from Muslims, Christians and more secular Egyptians. Abolfotoh was shown winning just over 27 percent of the vote.
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Director, Administrative Services
Bachelor of Science in Accounting, Marquette University
Currently seeking a double Master in Leadership/Master of Arts in Public Service, Marquette University
Provide leadership that will help MUMC sustain and enhance the mission of the department and the Division of Student Affairs
Active member of the W.W.H.E.L. association, PyraMED user group, and the Marquette Diversity Council.
Volunteering for the PGA and First Tee organizations; Active volunteer in the community; Enjoy golfing, biking, traveling and spending time with my family; Proud season ticket holder – Marquette Women's Basketball team


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Each Application Server instance has a security policy file specifying its security policies or rules. Unless modified, the default security policies would prevent the HTTP or HTTPS tunnel servlet from accepting connections from the Message Queue message broker. In order for the broker to connect to the tunnel servlet, you must add an additional entry to this policy file:
Open the security policy file.
The file is named server.policy and resides at a location that varies depending on your operating system platform. On the Solaris platform, for example, the policy file for server jeeves would be located at
where appServerRoot is the root directory in which Sun Java System Application Server is installed.
Add the following entry to the file:
grant codeBase "file:appServerRoot/glassfish/domains/domain1/jeeves /applications/j2ee-modules/imqhttps/- { permission java.net.SocketPermission "*","connect,accept,resolve"; };
Save and close the security policy file.


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The Kaskaskia College Community Education Office will offer a social networking class at the KC Vandalia Campus.
The class will be held from 9-11 a.m. on Saturdays, Nov. 13 and 20. The registration number for the class is COED 8037 VA01W.
Students will learn to use Facebook, Twitter and other social networking sites to their advantage. This course will include building pages, security and customizing pages. The fee is $20 for students under 60; students over 60 free of charge. Computer experience is required.
If you currently subscribe or have subscribed in the past to the The Leader Union, then simply find your account number on your mailing label and enter it below.
Click the question mark below to see where your account ID appears on your mailing label.
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Am I eligible?
To win a Shopify Commerce Award, you must be a Shopify Partner and your submission must be a store or merchant solution that launched between January 1, 2017 and December 31, 2017. Please read through our Official Rules for full eligibility requirements.
I don't live in the eligible countries for the Commerce Awards. Can I still participate?
We welcome you to the competition and would love to support you as you build innovative commerce solutions for your clients, however, you will not be eligible for the prizes listed on the Commerce Awards page.
Can I enter into multiple categories?
Yes! Ensure you fill out the application for each award you wish to be considered for. However, you are only eligible to win one award. Our judges will decide which category your application best reflects.
I nominated someone for a Commerce Award, now what?
Thanks for nominating a Shopify Partner for a Commerce Award! We'll reach out to your nominee to collect their details so they can be considered for an award.
How will I be notified if I've won?
If our judges select you as a finalist for an award, we will contact you via email by March 15, 2018.
How will my application be judged?
You can read more about how we're evaluating work in each category in the Judging section of our Official Rules. Our judges will be looking for innovative and forward-thinking commerce concepts.
Where can I find tips, tutorials, and guides on how to win a Commerce Award?
Check out our blog, webinars and guides for helpful insights.
When will you announce the winners?
Winners will be announced in early 2018.
The application asks if I have permission from my client to apply. Is this required?
We will need to ensure you have permission from your client if your application is chosen for a Commerce Award.


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SYNOPSIS: Rib cracking comedy and astounding performance from Mercy johnson as illiterate Dumebi whose husband Frank Kenneth Okonkwo) sends to school to enhance her exposure. Reverse is the case as Dumebi did not only refuse to put enough effort to learn but also tears the school apart with her high level of illiteracy.
Produced By Collins Ezenwa(P COLLINS) and Directed By TCHIDI CHIKERE
There is a continuation to this movie check, below are links to the full videos:
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Dumebi In School 2: http://youtu.be/rR8rJ8juq0I
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Dumebi $ Bitterleaf Cynthia 2: http://youtu.be/S3juOpMljIE
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Learn more about Fox Hunting
In 2004 the government passed the Hunting Act which banned the practice of hunting mammals with dogs in England and Wales. The Act allows dogs to sniff out foxes but bans them from killing. The Act does not prevent hunters from using dogs to "drag hunt" which uses dogs to track and sniff out foxes. Proponents argue that fox hunting with dogs is a time honored tradition that supports rural communities. Opponents argue that killing foxes with dogs is cruel since the hunted animals suffer severe physiological and psychological stress during the hunt - whether they are killed or not. See recent Fox Hunting news


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This article was printed from mlb, originally published .
Read more news at: https://www.mlb.com/phillies/news
Phils pick Cozens has 'extraordinary power'
The kid can hit.
"He made a great impression here," Phillies assistant general manager of amateur scouting Marti Wolever said. "He really swung the bat well and really handled himself well. I think he answered a lot of questions."
So much so that on Tuesday, Philadelphia made the power-hitting Cozens, a left-handed outfielder from Chaparral High School in Arizona, its first pick of the second round in the First-Year Player Draft. Cozens, listed at 6-foot-6 and 225 pounds, was selected 77th overall, the second of two compensatory picks the Phillies received for losing right-handed reliever Ryan Madson to free agency.
He was the first position player drafted by the Phillies, projecting as a right fielder.
"He was really interesting," Phillies general manager Ruben Amaro Jr. said. "That was probably the guy I was most excited about. This is a kid that people knew about, but were kind of off of for whatever reason. I love the guy's power. Extraordinary power for a kid -- great body, runs well, seems to move pretty well, looks like a pretty decent athlete."
Cozens, who also worked out for the Rangers and was said to be high on their Draft board, was watching the Draft on the Internet when his name was called. His emotions at that moment?
"Relieved and happy," Cozens said succinctly by phone.
"I'd say definitely one of the best [days of my life]."
Cozens had committed to Arizona to play both baseball and football -- as a defensive end -- but he said on Tuesday that he will sign with the Phillies instead. He hit a state-leading 19 home runs in his senior season, breaking the school's record of 13 long balls set by current Major Leaguer Paul Konerko.
"That speaks pretty highly in itself," Wolever said.
Cozens led Chaparral to the Division I state title, clinching the championship with a walk-off, opposite-field home run. On Tuesday, a smiling Wolever compared Cozens' opposite-field hitting capabilities to Ryan Howard's.
Cozens, who has been described as low key and grounded, said he is a hard worker and just wants to be "an everyday MLB player one day."
Chaparral hitting coach Randy Ford lauded Cozens' dedication to baseball.
"He worked very, very hard," Ford said by phone. "Dylan won a state football title on a Saturday night, and on Monday night, he said, 'Coach, let's go work on hitting.' I tried to get him to take a few days off, and he wouldn't have it. That's his dedication."
His obvious athletic abilities aside, eligibility issues surrounded Cozens in high school. He was kicked off the team at Desert Mountain High School, according to reports, and transferred to Chaparral, where he was ruled ineligible for a year. More questions were raised after Cozens reportedly began playing for Chaparral before the full year of ineligibility had passed, but he was eventually ruled eligible.
The Phillies don't seem concerned with any possible character issues.
"We spend a lot of time on the makeup and the families, and we really believe that this kid's got what it takes," Wolever said. "We were sold enough to go ahead and make that choice."
"Yeah, I think he got into a couple tussles," Amaro said. "But that's OK. I don't have a problem with that."
Aside from the perceived makeup issues, Ford said some Major League clubs might have not had as much interest in Cozens because he also played football.
"My dialogue with Dylan was he definitely wanted to do this," Ford said of Cozens' desire to play professional baseball. "This is the day that he wanted to see happen. I'm very happy for him."
The Phillies are happy to have him.
"This guy bounced around a little bit," Wolever said. "People got on him late. People heard all of the information, [but] they didn't do their homework. They didn't find out what he was made of and his character. And we did. Once we saw him play, we thought this is a guy that we really have a lot of interest in, so let's find out everything else that goes with it. And I think we have. And we feel really good about the selection."


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Yankton Man Faces Murder Charge in October Death
YANKTON, S.D. (AP) - A Yankton man has been indicted on a second-degree murder charge in the death earlier this fall of another man from the city.
Fifty-seven-year-old Darwin Jans is accused of assaulting 59-year-old Larry Goodman on Sept. 19. Goodman died Oct. 6 of what an autopsy concluded was a head injury.
The Daily Press & Dakotan reports that Jans remains jailed on a $100,000 cash-only bond. It was not immediately clear if he had an attorney. He faces life in prison if convicted.
Copyright 2012 by The Associated Press. All rights reserved. Material may not be redistributed.


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DailyDirt: 'Disgusting' Alcoholic Drinks (Besides Egg Nog)
from the urls-we-dig-up deptSome people like egg nog, some people don't. With the main ingredients being sweetened milk/cream and whipped eggs (and maybe salmonella), it's no wonder people added alcohol to make it drinkable. But the beverage is popular enough that there are tons of variations on it. Pretty much any kind or combination of hard liquor can be added, and it can be spiced up with spices like cinnamon and nutmeg. If you like egg nog, especially the alcoholic part, maybe you'll also like the following "disgusting" alcoholic drinks.
- The Powder Room in Los Angeles is offering a swanky $500 alcoholic milkshake called The Velvet Goldmine. This is no ordinary milkshake -- it features premium spirits, edible gold, and Belgian chocolate, and it's topped with a Swarovski Nirvana Montana crystal ring that retails for $190. [url]
- If you like heartburn, then you might like 100,000 Scovilles Naga Chilli Vodka. This spicy vodka has the same level of heat as a Habanero chili, plus it's got 40% alcohol. Check out the warning video for this product! [url]
- Craving tacos and an alcoholic beverage? Two words: Taco Gin. Apparently, gin is just "flavored vodka." To create Taco Gin, steep taco seasoning in 100-proof vodka in a jar for at least 48 hours, strain the mixture through a coffee filter, and cut it down to 90-proof by diluting with a bottle of 80-proof vodka. It shouldn't be a surprise that the reaction to the taste test was "That's awful!" [url]


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And no, "weeding" in this case doesn't have anything to do with gardening or the Black Crowes.
In this case, according to Yankelovich MONITOR, it means being "blackballed" for superficiality in favor of substance and accountability.
In today's world of myriad choices, it's easier than ever for consumers to walk away from brands, restaurants and retailers that they don't see as honest. After all, why exert the energy and spend the time when you can walk to the other side of the mall or click to another window and get something better.
It's remarkable how the wisdom of a cousin in grocery retailing and a five-figure subscription to a consumer trend monitor can overlap. Here's how Cousin Ron and Yankelovich recommend you improve customer service in order to delight and retain customers:
- Hire great people. Restaurants, retailers and manufacturers are all guilty of placing too little emphasis on hiring, training and retaining talented and passionate brand ambassadors. Trust us, your more successful peers and competitors do this. No excuses, now. Fix it.
- Remove the word "no" from your vocabulary. You have two choices. Make it happen or be willing to risk the customer moving on to something better.
- Don't wait for them to ask you. If there's even a slight chance a question might arise, publish an answer to it on your Web site and prepare your people to be able to answer it.
- Show caring through customization. Every neighborhood is different. Every market segment is unique. That's why they're called neighborhoods and segments-because they're full of neighbors and segs who want something a little different. Wherever possible and profitable (especially long term), give it to them. It shows you care, and it builds loyalty.
Have a profitable, customer-focused, consumer-friendly day.


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Gland, Switzerland (IUCN) 21.06.01. The rediscovery of a Mauritian plant last seen in the wild in 1863 has spurred collaborative efforts on the island to help save the species.
Trochetia parviflora, a small, attractive tree found only on Mauritius, was recently rediscovered by Vincent Florens and his colleague Jean-Claude Sevathian during their third expedition to find the species. Vincent is a member of the Indian Ocean Island Plant Specialist Group, of IUCN's Species Survival Commission. The pair found one plant clinging to a rocky slope in the Corps de Garde Mountain Nature Reserve, some 6km from the nearest area in which it was previously known.
"We could not believe we had found the species, it seemed too good to be true", said Vincent. "We both knew the plant very well from old herbarium samples and knew what it was immediately. The plant is exquisite with its curvy trunk, dense branches, small pointed leaves and pale green fruits, and has survived for centuries in the harsh conditions of the cliff edge."
Since the initial rediscovery, Vincent and Jean-Claude have intensified their search on the mountain and have now found 63 plants. Although thrilled by the find, Vincent is concerned for the continued survival of the species. "All the plants are in a precarious situation, within a 500m stretch of mountain slope which is vulnerable to landslides and fire that could destroy the population", he said.
The genus Trochetia is well known in Mauritius as Trochetia boutoniana is the country's national flower, known locally as Boucle d'Oreille (French for ear-ring). The flora of Mauritius is one of the most endangered in the world with nearly 300 threatened species -approximately 28% of the island's estimated 1,100 native species. The main threat is invasive introduced plant species that have taken over almost all the island's natural habitats, and are choking the small area inhabited by T. parviflora. Introduced rats and monkeys eat the tree's fruit, and the plants are attacked by termites. Vincent and Jean-Claude have taken cuttings from the trees and collected seeds to try to propagate the species to help boost the wild population.
Efforts to secure the species have been boosted by a $2,500 grant from the Chicago Zoological Society applied for by the Indian Ocean Island Plant Specialist Group. Work to protect the wild population and propagate new plants will involve the Mauritius Herbarium Arboretum, part of the Mauritius Sugar Industry Research Institute, Forestry Service nurseries, and other nurseries of the National Parks and Conservation Service.
Surveys by Vincent, his sister Danielle Florens, who is also a member of the Specialist Group, and Jean-Claude have increased the known number of native species on Corps de Garde by 20%. All three work for the Mauritius Herbarium. Vincent and Jean-Claude have dedicated the rediscovery to their friend, Adrien Wiehe, a local priest who has a keen interest in Mauritian botany. Now in his 70s, it has been his lifetime dream to rediscover this plant, and only four days before the event, he was looking for rare plants on the same mountain.
"Now that this almost mythical species has been rediscovered maybe we can hope that one day, people could find other 'extinct' species clinging to life in other remote areas", Vincent added.
For more information contact:
Vincent Florens Tel: +230 454 1061 or +230 686 2357 [email protected]
Jean-Claude Sevathian Tel: +230 454 1061 or +230 466 7780
Anna Knee Tel: +41 22 9990153 [email protected]


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To Gillian Flynn, dread is "that sense that you've got a rope around your middle and it's pulling you toward something." That's what the author of "Sharp Objects," "Dark Places" and the breakout hit "Gone Girl" wants you to feel while reading her work, rather than old-fashioned fear. "To me, dread is always the more potent feeling that I like to talk about," she said in a phone conversation from her Ukrainian Village home, where she lives with her husband and son. Here are five quick hits with Flynn.
Which "Gone Girl" character--Nick or Amy--she empathizes with more:
Both at different points in the novel. We agreed that at some point, all women have thought about getting the type of revenge Amy exacts on Nick. We're just not exactly crazy enough to go through with it.
How much influence she's had over the film version of 'Gone Girl':
Flynn adapted her book into the script, but wasn't involved in the casting process, though she said she was happy with the choices of Ben Affleck as Nick and Rosamund Pike as Amy. She's also ventured to Missouri to visit the movie's set.
The impetus that really made "Gone Girl" take off:
Flynn has no idea, but suspects the book mostly grew through word-of-mouth. She recalls sitting in her backyard with her husband on the Fourth of July last year and toasting that the novel had hit No. 1.
Her favorite Chicago author of the year:
Marcus Sakey, author of "Brilliance." While on a trip to Paris, Flynn said she would fantasize about being able to return to her hotel room and continue reading. Now that's the definition of a can't-put-it-down novel.
Where she hangs out in Chicago:
Flynn said you can find her and husband Brett Nolan at Innertown Pub. She's also a fan of taking a mid-day break to walk around her neighborhood and by the lake to clear her head during writing.
About her next book:
What, you think she was going to give away any secrets? Flynn took the entire month of November off to rejuvenate, but now that December has rolled around, she's back to writing in her basement office. She told me she's got the first sentence of her novel in her head, and hopes to write more about Chicago this time.
Want more? Discuss this article and others on RedEye's Facebook page.


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Built at the turn of the 20th century is the Harris school. It has been sold by the city after years of neglect. The last class of the school was in the 1980s. The developer will have to work with neighbors in that this neighborhood has deep pockets. It is a very prime piece of property.
The United States is one of the most diverse countries on earth, jam packed full of amazing sights from St. Patrick's cathedral in New York to Mount Hollywood California.The Northeast region is where it all started. Thirteen British colonies fought the American Revolution from here and won their independence in the first successful colonial rebellion in history. Take a look at these rolling hills carpeted with foliage along the Hudson river here, north of New York City.The American south is known for its polite people and slow pace of life. Probably they move slowly because it's so hot. Southerners tend not to trust people from "up north" because they talk too fast. Here's a cemetery in Georgia where you can find graves of soldiers from the Civil War.The West Coast is sort of like another country that exists to make the east coast jealous. California is full of nothing but grizzly old miners digging for gold, a few gangster rappers, and then actors. That is to say, the West Coast functions as the imagination of the US, like a weird little brother who teases everybody then gets famous for making freaky art.The central part of the country is flat farmland all the way over to the Rocky Mountains. Up in the northwest corner you can find creative people in places like Portland and Seattle, along with awesome snowboarding and good beer. Text by Steve Smith.


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Instapaper Starred Items
- "Windows 8 is a disaster. Period."
- The 35 Best Times Someone On Facebook Thought 'The Onion' Was Real | Thought Catalog
- Anatomy of a password disaster - Adobe's giant-sized cryptographic blunder
- MacBook Pro with Retina Display redefines the concept of a 'pro' laptop Review | Macworld
- Apple's MacBook Pro Is Just One Point Short of Perfection - State of the Art - NYTimes.com
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Tag Archives: crashplan
My horribly incomplete backup plan
It's been a long time since I took a hard look at my backup situation, but a series of blog posts in my reader has caused some naval gazing. A long time ago in a computer far far away My … Continue reading


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Resources >> Browse Articles >> Career Change
Resources >> Browse Articles >> On the Job
How to Avoid Getting the Axe From Your Nursing Job
Georgia Price | NursingLink
1. Go Beyond Your Job Description
You were hired as a diagnostic medical sonographer. Your job description is fairly straightforward. You take ultrasounds, maintain the equipment, and report on the results. You may be thinking, "What else can I do?" The answer is, "Lots." Show you are committed to your career by taking a continuing education class or taking a new co-worker under your wing as his/her mentor. Show interest in a conference that is coming up or read up in the lasted sonography news.
No matter your position, there is no shortage of places where you could put in the extra effort. That's not to say you should volunteer to work 90 hour weeks, but if you are truly interested in your job, let it be known. If it comes down to you versus the guy next to you, you extra interest can make all the difference.
Earn Your Nursing Degree!
Featured Opportunity
Do you enjoy working with people and helping them feel better? When you pursue a degree in nursing, you can learn how to help people get healthy and stay healthy.
2. Own Up to Mistakes
We all make mistakes. If we're lucky, the mistake doesn't hurt anyone and is forgotten about. Unfortunately, in the nursing field, a mistake can cost you your career. We don't need to tell you to be cautious in your job. But if you do make an error, own up to it. You may have given Mrs. Jones the wrong test results, but if you explain the situation to the patient and your supervisor as soon as you realize it happened, you can avoid a world of hurt. Plus, taking responsibility for your actions rather than trying to hide a mishap shows that you are mature and an employee who is worth investing in.
3. Remain Upbeat!
It's a scary economy out there! If your hospital or clinic starts laying people off, resist the urge to retreat into a corner, curl into the fetal position, and hope for the best. Keeping a positive attitude despite rough times can add to your appeal! Remember, you still have your job and you (hopefully) still love it. Continue to greet patients and co-workers with a smile and you may avoid the axe.
4. Solicit Feedback
If you are worried about whether or not you'll have a job tomorrow, one of the best things you can do is find out how you've been doing. Feedback from supervisors and peers can help you appraise what you need to start or stop in order to make sure you don't get laid off. Don't try to be sneaky about an information evaluation. Set up a meeting with your supervisor so you can speak frankly about any concerns you may have. Getting input from a trusted colleague can give you an idea of how others on your team view you and where you stand with other employees.


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Lexington, Ky — Now that Royce Pulliam, formerly the largest Gold's Gym International franchisee, has left the Gold's brand behind to create his own brand, Urban Active Fitness, a big piece of Gold's pie has opened in Kentucky, Ohio and Tennessee.
As of press time, Gold's Gym had not returned calls to comment on what will happen to Pulliam's three-state territory. The company could keep all or part for corporate facilities or sell the territory to one or several franchisees.
The thought of competition from his former franchisor doesn't seem to phase Pulliam, CEO of Global Fitness Holdings, Lexington, KY.
"Gold's has done a lot for us," Pulliam says. "But at the end of the day, will we be competitors? We will be, but hopefully, we'll be very friendly competitors. We don't have any intent to go out targeting their markets and opening stores across the street. That's not how we do business, and I don't think they do either."
Pulliam left the Gold's Gym brand behind after taking on Laurel Crown Partners LLC, a Los Angeles-based private equity firm, as a partner in the business. Both groups had separately and unsuccessfully bid for the Gold's Gym chain in 2004 before becoming partners. With the added backing and input from Laurel Crown Partners, Pulliam began expanding more quickly than he had in the past. He soon ran out of opportunities in his Gold's Gym territory, he says.
Beginning Dec. 1, all of Pulliam's 25 former Gold's locations will be renamed Urban Active. During the next three to four years, Pulliam plans to open 50 more clubs. He will soon have almost 40 clubs in Kentucky, Ohio and Tennessee, so most of the new growth will be outside those three states. However, he plans to stay mainly in the Midwest and East, so it will be easier for him to keep an eye on the growth, he says. So far, he has letters of intent on 20 locations outside those three states, and a few leases are even being prepared, he says. He expects the first clubs to open outside his old territory in late 2008 or early 2009.
In two years, Pulliam expects to report revenue of about $150 million, he says. That revenue won't come just from the new clubs. It will also come from a new retail piece that Pulliam is adding.
"With our branding, we feel like we now have a commodity," he says. "We're looking to hire a top-notch player in the retail division to run our juice bars and design our clothing. We feel that's got some potentially big upside."
Pulliam is thinking big, saying that in five years he can see the Urban Active Fitness name being as big as 24 Hour Fitness or Gold's Gym.
"My partners and I believe in our team that much," he says. "We believe that if we stay focused and stay in our parameters and model — and if it doesn't fit in our box, we don't do it — that we have that potential. If you ask our members, they'll tell you the same thing."
In the past 24 months, Pulliam has been going after a higher income demographic, and that probably won't change with the new clubs.
"We feel that's the sweet spot for us with personal training," he says. "Personal training is about 25 percent of our business. We feel that education and income leads to a better business model."
All pricing will remain the same at $49 to $59 per month in membership dues.
Pulliam has two prototypes for the Urban Active Fitness clubs that will appeal to that demographic, he says. One fits on 3 1/2 acres and the other fits on 6 acres. The clubs will range from 42,000 square feet to 58,000 square feet. The smaller clubs will have the same amenities as the larger clubs, including swimming pools, an indoor track, half- or full-court basketball, high-end locker rooms, tanning facilities, and a children's area with computer stations, equipment and games.
Pulliam's existing clubs will receive an internal facelift, including new color schemes and an update to a more upscale branding scheme, he says.


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Goals for Radiation Therapy
Definitive Radiation Therapy
Definitive radiation is administered with the goal of achieving long-term control of the disease. Depending on the part of the body where the tumor is located, most veterinary patients treated with definitive protocols are treated over a three to four week period. This allows the total radiation dose to be delivered as a number of smaller doses or "fractions". Fractionation makes it possible for normal cells to repair themselves of radiation damage between treatments. Small tumors can be treated by radiation therapy as the primary therapy for long-term control. We can also use radiation therapy in conjunction with surgery for many tumors. Depending on the location, acute, temportary side effects may occur. These side effects normally heal quickly and are generally resolved within three to four weeks after the course of radiation therapy is completed. Advances in technology, such as IMRT, are helping to minimize acute effects.
Palliative Radiation Therapy
The goal of palliative therapy is to relieve pain and other clinical signs to improve and help maintain a patient's good quality of life with minimal side effects. The goal of palliative radiation therapy is to shrink or stabilize the growth of the tumor and avoid significant side effects. Most palliative radiation therapy protocols use fewer fractions, a higher dose per fraction, and a lower total dose compared to definitive protocols. These protocols may involve weekly treatments or treatments given over the course of a few days. Palliative protocols are often used when the patient has advanced cancer with metastasis (tumor spread to other locations), or some other critical health condition that would limit life expectancy. Palliative therapy rarely causes acute side effects. Palliative therapy may be recommended for, but is not limited to, tumors causing bone pain, masses occupying a large space and causing obstruction or discomfort, tumors compressing the spinal cord, and invasive nasal or oral tumors.


text: What is it to see real estate through a different lens? It's not enough to be on top of the market. It takes looking ahead, to envision what could be. And to make what will be, with the application of smart strategy, creative talent and a relentless drive to exceed. More about Our Vision. >


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U.S. News
New Mexico: Tele-Treatments -- Video Talks Keep Medical Providers in the Know
January 11, 2012
Adapted from:
Since 2003, a University of New Mexico (UNM) program has brought primary care clinicians from across the state together for weekly video teleconferences to improve treatment outcomes for hepatitis C patients.
"The goal of this model was to treat hepatitis C patients everywhere in New Mexico as well as they were treated at the university," said Dr. Sanjeev Arora, a UNM hepatologist and founder of Project ECHO (Extension for Community Healthcare Outcomes). The project also serves as a training program and is A "force multiplier" that allows a small group of specialists to recruit local clinicians in treating hard-to-cure illnesses, he said.
Each Wednesday, about a dozen clinicians take part. Participants on the hepatitis C teleconferences, which are led by Arora, include physicians and nurse practitioners from clinics in Carlsbad, Las Cruces, Albuquerque, Las Vegas, and Connecticut.
Participant Debra Newman, a physician assistant at El Centro Family Health in Española, receives hepatitis C patient referrals from physicians throughout northern New Mexico. On a recent teleconference, she described working with a patient with end-stage liver disease experiencing severe side effects in his 74th week of treatment. "We need to get this patient through treatment and cure the virus," said Arora, since the man would otherwise die or need a transplant.
Project ECHO now has expanded to sponsor clinics addressing 20 illnesses, including HIV/AIDS, with clinicians at 255 sites statewide participating. Its $4 million annual cost is supported by grants from funders including the Robert Wood Johnson Foundation. For more information, visit: http://echo.unm.edu/.
Albuquerque Journal
12.30.2011; Olivier Uyttebrouck
HealthHIV and Clinical Care Options Announce Partnership to Deliver Education to HIV Primary Care Providers
This article was provided by CDC National Prevention Information Network. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update.
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Justin Bieber Compares Noisy Party to 'The Great Gatsby' [VIDEO]
Justin Bieber had the cops called on him three times in one night because of a way-too-loud party this weekend, but he doesn't seem too upset about it.
The Biebs hosted a rager on Friday night (Nov. 15) with over 100 people in his Calabasas, Calif. mansion, including Snoop Lion. Bieber's neighbor -- the same one whose face he allegedly spit in -- called the cops around 1AM, when sheriff's deputies went to the mansion and asked them to keep it down.
Around 3AM, the same neighbor called the cops again. Still, the noise continued, and at 5:30AM the neighbor not only called the cops one more time, but also filed a police report saying that Biebs was disturbing the peace in their otherwise quiet gated community. (The neighbor also said cops smelled weed, but that no one was arrested.)
When TMZ cameras caught up with the 'All Bad' singer, he didn't express any remorse -- or information -- about the shindig. He did, however, say, "You shouldn't have missed it. It was wild. It was wild! It was some 'Great Gatsby' s---."
Too bad Bieber's neighbors don't appreciate him being young and beautiful ... because he's also young and loud!


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The West Tennessee Healthcare Foundation, now in its third decade, has a rich history of service to the community. From humble, grass roots beginnings, the Foundation's work has grown across the state of Tennessee and now reaches around the globe to help those in need.
As a community foundation, we serve as a conduit through which charitable donations are made. We have more than 500 community funds with a wide range of missions from the arts to education to providing health care for those unable to afford it. Each year, millions of dollars are invested back into our community, our state and our world to change the lives of others.
The Foundation has also become a resource in charitable giving by providing a myriad of giving avenues. From donor advised funds to estate planning to endowment management, we assist our donors in meeting their charitable goals in the areas in which they are most passionate.
Let us help you put your passion into action.


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Cadillac ELR plug-in hybrid looks badass
GM showed off this new Caddy at the Detroit Auto Show earlier this year. It looks pretty awesome and it's basically a luxury version of the Chevy Volt as Cadillac brings plug-in hybrid technology to the Cadillac brand.
When General Motors (GM) decided to make a plug-in hybrid several years ago, there was a lively discussion behind closed doors about whether the first model to showcase the expensive technology should be a Chevrolet or a Cadillac. The Chevy advocates won and the Volt was born. History suggests that may not have been the right choice. The Volt—the first car to mix all-electric capabilities with an auxiliary gas engine to extend its driving range after the battery's depleted—has had disappointing sales. Republicans during the presidential campaign pilloried it as a symbol of the failings of President Obama's auto-industry bailout.
GM has decided to take a second stab at Volt technology, and this time it's heading upmarket, with the Cadillac ELR plug-in hybrid, introduced Jan. 15.
That may be going a bit too far, as there's nothing to indicate that a Cadillac would have fared any better as GM's first plug-in option. The technology is just getting started, and the Volt's price point was always an issue.


text: On Thu, 23 Jan 2003, Chris Steward wrote: > Hi, > > We're in the process of setting up a new 32-node dual-athlon cluster running > Redhat 7.3, kernel 2.4.18-19.7.smp. The configuration is attached below. We're > having problems with nodes hanging during calculations, sometimes only after > several hours of runtime. We have a serial console connected to such nodes but > that is unable to interact with the nodes once they hang. Nothing is logged > either. It seems that running jobs on one CPU doesn't seem to present too much > of a problem, but when the machines are fully loaded (both CPU's 100% > utilization) errors start to occur and machines die often up to 8 nodes > within 24 hours. Temperature of nodes under full load is approximately 55C. > We have tried using the "noapic" option but the problems still persist. Using > other software not requiring enfuzion 6 also produces the same problems. I'd suspect the following (in order): Heat. Make them colder. They'll like it. This may involve upgrading internal fans and setting the temperature down in the room (55C notwithstanding). Athlons just hate heat, and a failure under load always makes one wonder... Electricity. See list archives for our nightmarish experience with a carelessly wired machine room. In particular, multiphase node supply lines should NOT share a common neutral. Try spreading the load out some. BIOS. There are good BIOS and bad BIOS (you don't say what motherboard, but I think this is true pretty much across the board). Sometimes just reflashing the bios to the latest update fixes everything. Sometimes flashing back FROM the latest update fixes everything. Go figure. Weirder problems associated with specific node configuration. We had problems with particular risers. We had problems with specific video cards. These are the problems that are sometimes fixed with the noapic option. Sometimes. Try cycling your hardware about a bit, if you can, to see if some particular card is a problem. AMD certifies power supplies for these motherboards. They mean it. If a vendor tried to convince you that "any old" power supply would work, that would be incorrect. It might or might not "work", but will it work stably? The dual Athlons are a bit touchy about power (see above). AMD and the motherboard vendor certifies memory for these motherboards. Again, they mean it. Typically certified ECC DDR, high end memory. > The seek feedback on the following: > > 1/ Are there issues using redhat 7.3 as opposed to 7.2 in such > a setup ? Not to my experience. > 2/ Are there known issues with 2.4.18 kernels and AMD chips ? > We suspect the problems are kernel related. Again, not to my experience. As in we never had any of our problems magically go away when changing 2.4.x kernels (in spite of our hopes). > 3/ Are there any problems with dual-athlon clusters using the > MSI K7D Master L motherboard ? I don't know (we opted for the Tyans) but I wouldn't be surprised. Some of the problems may derive from the AMD 76x chipset itself; others may come from > 4/ Are there any other outstanding issues with these machines > under constant heavy load ? See above. We've had very similar problems with dual Athlons (Tyan 2466 and especially 2460 motherboards). We have finally approximately stabilized our cluster, but it wasn't easy and we still have a smattering of "random" crashes. Fortunately, they are very productive when they are finally running well. We have also observed a weak dependence on the particular jobs being run on the nodes. Some people run jobs that seem to initiate a crash while others do not. It's not obvious why -- the cpu and so forth can be 100% loaded either way. Possibly related to the compiler used (fortran code bad, gcc good?), possibly related to memory used or something "done" in the code -- too difficult to run down. HTH, rgb > > Any advice/help would be greatly appreciated. > > Thanks in advance > > Chris > > -------------------------------------------------------------- > Cluster configuration > > node configuration: > > CPU's: Athlon MP2000+ > RAM: 1024Mb Kingston PC2100 DDR > Operating system: Redhat 7.3 (with updates) > Kernel: 2.4.18-19.7.xsmp > Motherboard: MSI K7 Master L motherboard (Award Bios 1.5). > Network: On-board PCI (Ethernet controller: Intel Corp. > 82559ER (rev 09)). (Using latest Intel drivers, "no sleep" option set) > > head-node: > > CPU single Athlon MP2000+ > > Dataserver: > > CPU: single Athlon MP2000 & > Network: PCI Gigabit NIC > > Network Interconnect: > > cisco 2950 (one GBIC installed) > > Software: > > Cluster management Enfusion 6 > Computational Dock V4.0.1 > > > > > _______________________________________________ > Beowulf mailing list, Beowulf at beowulf.org > To change your subscription (digest mode or unsubscribe) visit http://www.beowulf.org/mailman/listinfo/beowulf > Robert G. Brown http://www.phy.duke.edu/~rgb/ Duke University Dept. of Physics, Box 90305 Durham, N.C. 27708-0305 Phone: 1-919-660-2567 Fax: 919-660-2525 email:rgb at phy.duke.edu


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The long-awaited video game, Captain Novolin, is now available to the public, and in time for the holidays. Test markets have shown Captain Novolin to be a hit with children who have diabetes, and their friends and family enjoy it also.
Captain Novolin is the first superhero to have diabetes. The goal of the game is to help him stop the alien invaders and stay healthy by taking insulin, eating properly, and exercising. Jumpin' Jelly John, Fizzy Floyd, Larry Licorice, and Blubberman are just a few of the aliens Captain Novolin fends off during his journey to rescue Mayor Gooden, who has been kidnapped by them. Kids gain a fundamental understanding of diabetes and management while having fun playing the game.
Raya Systems, in conjunction with Novo Nordisk sponsorship, developed Captain Novolin to help children with diabetes, their friends and families learn and communicate about diabetes. Captain Novolin is available only for Super Nintendo and sells for $59.95. For ordering and information call Raya Systems at 415-949-3933.


text: On Sun, 21 Nov 2004 john.hearns at clustervision.com wrote: > The fact that there are fewer Opteron based systems in the Top 500 is > irrefutable (I didn't know this) but it makes me uneasy to extrapolate > this to the impending death of a CPU. > > I DO agree (and let's have some debate here) that Nocona is bound to make > big inroads. Sure. We can start with the fact that the Top 500 list is irrelevant. It is a hardware vendor pissing contest. I criticized it pretty strongly in a recent CWM column. Let's see: a) It lists identical hardware configurations as many times as they are submitted. Thus "Geotrace" lists positions 109 through 114 with identical hardware. If one ran uniq on the list, it would probably end up being the top 200. At most. Arguably 100, since some clusters differ at most by the number of processors. What's the point, if the site's purpose is to encourage and display alternative engineering? None at all. b) It focusses on a single benchmark useful only to a (small) fraction of all HPC applications. I mean, c'mon. Linpack? Have we learned >>nothing<< from the last twenty years of developing benchmarks? Don't get me wrong -- linpack is doubtless a useful measure to at least some folks. However, why not actually present a full suite of tests instead of just one? Vendors would hate this, just like they hate Larry Mcvoy's benchmark suite, because it makes it so difficult to cook up a cluster that does just one thing (runs Linpack) well... c) It totally neglects the cost of the clusters. If you have to ask, you can't afford to play, I suppose. Is it any surprise that the list is dominated by the goldest-plated of the gold plated vendors? Obviously many of the folks who build and buy the systems that make the list aren't troubled by the spectre of cost-benefit. So we have absolutely no idea what BlueGene/L costs for the R it produces compared to SGI's Altix 1.5 GHz cluster that comes in at number 2. Even if we did know their cost, we would be unlikely to know their true cost -- at best the cost after the vendor discounted the system heavily for the advertising benefit of getting a system into the top whatever. I could go on. I mean, look at the banner ads on the site. Vendors love this site. If it didn't exist, they'd go and invent it. If they want me to take the top500 list seriously, they could start by de-commercializing it, running a pretty stringent unique-ing process on the submissions and accepting only the first of a given design or architecture, especially for clusters that are more or less turnkey and mass produced. Then they could run a SERIOUS suite of benchmarkS (note plural) on the clusters, one which (like SPEC) attempts to provide useful information about things like latency, bandwidth, interconnect saturation for various communications patterns, speed for a variety of actual applications including several with very different computation/communication patterns (ranging from embarrassingly parallel to fine grained synchronous). Scaling CURVES (rather than a single silly number) would be really useful. I mean, this site is "sponsored" by some presumably serious computer science and research groups (although you'd never know it to look at all the little flashy things blinking Myrinet, Atipa, Tyan, IBM from the sides of the listings compared to the tiny little corner where the sponsoring institutions are listed). If they want to do us a real public service, they could do some actual computer science and see if they couldn't come up with some measure a bit richer than just R_max and R_peak.... Now, with that said (and it needed to be said, it did it did) the only thing most real cluster computer buyers care about is price/performance. To be more specific, price/performance on their particular application(s). At a guess, some 2/3 to 3/4 of all cluster computer users are doing something fairly coarse grained that doesn't use anything at all that linpack is relevant to as a measure of performance. This is probably true even on many of the clusters in the top 500. AMD has more or less "owned" the price/performance sweet spot for the last two years. If you have LIMITED money to spend and want to get the most work done for your money, you buy Opterons, at least at this particular moment and for most of the applications I've heard of that have been compared. Could Nacoma change this? Sure, if Intel drops its margins, but historically they've avoided doing this. It is also WAY early to see if AMD's road map "beats" Intel's or vice versa -- there are a lot of changes lined up in both architectures where getting to 64 bits was only the first step. So Nacoma could easily end up being both more expensive and slower, at least in the medium run. I personally am currently very fond of my Opteron-based systems and would cheerfully buy a lot more if only somebody would give me the money to do so. In a year, though, or two or four, who knows what I'd buy? I don't pick Opterons because I'm "fond" of AMD or "hate" Intel. I'm equally fond of both and hate neither one of them. I will, however, buy the price/performance winner because it is my work that will suffer if I don't. The only good reason to deliberately pick a more expensive architecture is if there are issues with reliability (either software or hardware). At the moment I'm unaware of any issues at all with Opterons -- they run "perfectly" with FC2 and later, and I'm still waiting for our first hardware failure from our Opteron stack after close to a year under nearly continuous load. SO I'd have to say that I doubt that the authors of the article were particularly well informed, and that AMD is likely to be around and kicking for a few years yet. Look, even the Power series hasn't disappeared and it has almost no top 500 presence at all, if you discount BG itself as IBM showing its marketing clout and finding a use for 700 MHz CPUs in Very Large Quantities... rgb Robert G. Brown http://www.phy.duke.edu/~rgb/ Duke University Dept. of Physics, Box 90305 Durham, N.C. 27708-0305 Phone: 1-919-660-2567 Fax: 919-660-2525 email:rgb at phy.duke.edu


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Michael Ondaatje on "Warlight: A Novel" at the 2018 Miami Book Fair
Michael Ondaatje on "Warlight: A Novel" at the 2018 Miami Book Fair interviewed by Jeffrey Brown.
From the internationally acclaimed, best-selling author of The English Patient: a mesmerizing new novel that tells a dramatic story set in the decade after World War II through the lives of a small group of unexpected characters and two teenagers whose lives are indelibly shaped by their unwitting involvement.
In a narrative as beguiling and mysterious as memory itself—shadowed and luminous at once—we read the story of fourteen-year-old Nathaniel, and his older sister, Rachel. In 1945, just after World War II, they stay behind in London when their parents move to Singapore, leaving them in the care of a mysterious figure named The Moth. They suspect he might be a criminal, and they grow both more convinced and less concerned as they come to know his eccentric crew of friends: men and women joined by a shared history of unspecified service during the war, all of whom seem, in some way, determined now to protect, and educate (in rather unusual ways) Rachel and Nathaniel. But are they really what and who they claim to be? And what does it mean when the siblings' mother returns after months of silence without their father, explaining nothing, excusing nothing? A dozen years later, Nathaniel begins to uncover all that he didn't know and understand in that time, and it is this journey—through facts, recollection, and imagination—that he narrates in this masterwork from one of the great writers of our time.
How Writers Build Authenticity Into Diverse Worlds | New York Comic Con 2018
Diversity and representation had never been more important in Science fiction and fantasy. In the era of #OwnVoices, how do writers craft sci-fi or fantasy stories using their own experience to create diverse and compelling worlds? Featuring authors Marlon James, Tochi Onyebuchi, Maura Milan, Julie Kagawa, Sam J. Miller, and moderated by Ali T. Kokmen.
Minneapolis – Be The Facts You Wish To Read: A Press Freedom Discussion
With an overflow in the amount of information that is readily available to us as readers due to the advancement of technology, it may be difficult to understand the facts that are presented to us as consumers of the news. The Target Performance Hall located in Minneapolis, Minnesota, was the host location for an in-depth discussion about censorship, news literacy, and the importance of fact-checking with locally based writers and authors.
Panel members for this conversation included Sheila Regan and Sun Yung Shin along with PEN America Members Shannon Gibney, Caroline Casey, and Marya Hornbacher. This panel was moderated by Joanna R. Demkiewicz (The Riveter). When it comes to fraudulent news, you have an active role to play. After this evening, participants were able to take the steps necessary to understand how they can speak up for press freedom and learn to engage in productive dialogue.
Andrew Sean Greer: 2018 National Book Festival
Andrew Sean Greer discusses "Less" at the 2018 Library of Congress National Book Festival in Washington, D.C.
Speaker Biography: Andrew Sean Greer is the best-selling author of five works of fiction, including "The Confessions of Max Tivoli," which was named a best book of 2004 by the San Francisco Chronicle and the Chicago Tribune. He is the recipient of the Northern California Book Award, the California Book Award, the New York Public Library Young Lions Award, the O Henry award for short fiction and fellowships from the National Endowment for the Arts and the New York Public Library. His new novel is "Less" (Lee Boudreaux), winner of the 2018 Pulitzer Prize for fiction. Greer lives in San Francisco. He has traveled to all of the locations in this novel, but he is only big in Italy.
Ralph Gibson & Laurie Anderson | Self-Exposure
Self-Exposure is the autobiography of celebrated American art photographer Ralph Gibson. With his 80th birthday on the horizon in January 2019 and a career spanning over 50 years, Gibson is at a point of reflection in his life and work and decided to put pen to paper.
Writing in candid prose, Gibson takes the reader through his life and career from his earliest memories of growing up in California (the son of a Hollywood director, Gibson's childhood is touched by the old glamour of the silver screen: the likes of Orson Welles and Rita Hayworth make appearances) to his time in the navy and his continuous love affair with photography.
Gibson's memories are filled with rich characters and period details. Often moving, the narratives of his at times troublesome childhood provide a rich background to the charismatic artist Gibson has become. Gibson covers a range of topics such as music, Catholicism, his wife, Mary Jane, and a long line of fellow artists and photographers such as Dorothea Lange and Robert Frank. His ruminations on his life so far display a deep, thoughtful understanding and self-awareness that make this book a fascinating read in itself as well as an illuminating companion to his work.
What emerges is an insight into the mind of an incredible, highly decorated artist. Evocatively illustrated, Self-Exposure presents Gibson's life story alongside his photographic work. Designed and produced in close collaboration with Gibson, this large-format publication—as much a biography as it is an artist's book—is Gibson's most personal book to date.
Join us as Ralph shares his latest work with fellow artist Laurie Anderson.
Ralph Gibson was born in Los Angeles in 1939. In 1956 he enlisted in the navy, where he began studying photography. His work is widely exhibited and held in public collections around the world, such as the Stedelijk Museum, Amsterdam, and the Museum of Modern Art, New York.
Laurie Anderson is a American avant-garde artist, composer, musician and film director whose work spans performance art, pop music, and multimedia projects. Initially trained in violin and sculpting, Anderson pursued a variety of performance art projects in New York during the 1970s, focusing particularly on language, technology, and visual imagery.
Martha C. Nussbaum: The Monarchy of Fear
Acclaimed scholar and humanist Martha C. Nussbaum turns her attention to the current political climate crisis of party polarization, divisive rhetoric, and the increasing inability of two halves of the country to communicate with one another in her most recent work, The Monarchy of Fear. At the heart of the problem, Nussbaum sees a simple truth: The political is always emotional, and the psychological constant of fear of the other will always be at-the-ready to fuel the fires of anger, disgust, envy, and blame. Drawing on a mix of historical and contemporary examples, from classical Athens to the musical Hamilton, Nussbaum will discuss the emotions behind our political culture, and suggest a roadmap for where we might go next.
Kiese Laymon | Heavy: An American Memoir
Join us as Kiese Laymon shares his highly-anticipated forthcoming book Heavy: An American Memoir.
It's a searing memoir that explores what the weight of a lifetime of secrets, lies, and deception does to a black body, a black family, and a nation teetering on the brink of moral collapse.
With a commitment to facing hard truths, Heavy charts Laymon's early experiences of sexual violence and toxic masculinity growing up in Jackson, Mississippi; his complex and often painful relationship to his brilliant mother; first-hand experiences with racism in academia; and the physical manifestations of trauma, including obesity, anorexia, and gambling addiction, on his own body.
Kiese Laymon is a black southern writer, born and raised in Jackson, Mississippi. Laymon attended Millsaps College and Jackson State University before graduating from Oberlin College. He earned an MFA in Fiction from Indiana University. Laymon is currently a Professor of English and Creative Writing at the University of Mississippi. He is the author of the award-winning novel, Long Division and a collection of essays, How to Slowly Kill Yourself and Others in America. Laymon has written for numerous publications including New York Times, NPR, Los Angeles Times, Esquire, The Guardian, McSweeneys, Colorlines, The Best American Series, Ebony and many others. He is a contributing editor of Oxford American.
Lauren Hendricks: "Fighting Poverty with Data"
Lauren Hendricks is the Executive Vice President for Program Strategy and Institutional Relations at Grameen Foundation, a global nonprofit that creates breakthrough solutions spanning financial, agricultural and health services. Grameen uses digital technology and strengthen local partner networks to design and deliver solutions that open opportunity for women and families living in poverty.
Lauren leads a riveting discussion, giving a broad overview of Grameen's work to use new digital technology to solve the lingering problems facing the nearly one billion people still living in poverty today. She also gives a detailed overview of some of Grameen's work focused on data-driven solutions, including a new SAT4Faming Project, through which we are developing a geo data-enabled agriculture service and technology platform aimed at increasing the farm yields of smallholder cocoa farmers in Ghana. Lauren also discusses potential uses for data collected during Grameen Foundation projects that will enable the development community to better understand our beneficiaries and the field workers who interact with them.
RO Kwon on "The Incendiaries" at the 2018 Miami Book Fair
RO Kwon on "The Incendiaries" at the 2018 Miami Book Fair interview by Rich Fahle.
"Radiant...A dark, absorbing story of how first love can be as intoxicating and dangerous as religious fundamentalism." —New York Times Book Review
A powerful, darkly glittering novel of violence, love, faith, and loss, as a young woman at an elite American university is drawn into a cult's acts of terrorism.
Phoebe Lin and Will Kendall meet in their first month at prestigious Edwards University. Phoebe is a glamorous girl who doesn't tell anyone she blames herself for her mother's recent death. Will is a misfit scholarship boy who transfers to Edwards from Bible college, waiting tables to get by. What he knows for sure is that he loves Phoebe.
Grieving and guilt-ridden, Phoebe is drawn into a secretive cult founded by a charismatic former student with an enigmatic past. When the group commits a violent act in the name of faith, Will finds himself struggling to confront a new version of the fanaticism he's worked so hard to escape. Haunting and intense, The Incendiaries is a fractured love story that explores what can befall those who lose what they love most.
Alan Hollinghurst: "The Sparsholt Affair" | Talks at Google
Alan Hollinghurst is the award-winning author of "The Swimming Pool Library", "The Folding Star", and 2004 Man Booker Prize winner "The Line of Beauty".
In this talk, he reads from his first novel in six years, "The Sparsholt Affair", a multi-generational exploration of the legacy of a family scandal and the shifting attitudes towards England's gay community from World War II to the present day.
Reading Lu Xun Through Carl Jung
Carolyn Brown discussed her just-published book "Reading Lu Xun Through Carl Jung," which offers a unique approach to the short stories of the most famous modern Chinese writer, Lu Xun (1881-1936). Brown uses foundational elements of the psychology of Carl Jung (1875-1961), who with Freud was the founder of modern Western psychology, to illuminate key structures in the works of this great writer. Approaching these works from a unique direction, Brown's lecture will shed new light on the psychological patterns within Lu Xun???s most famous story, "The True Story of Ah Q."
Speaker Biography: Carolyn Brown is a scholar of Chinese literature and the former director of the John W. Kluge Center at the Library of Congress.
Esi Edugyan: The Waterstones Interview
Esi Edugyan's new novel, Washington Black, saw her shortlisted for the Man Booker Prize for the second book in a row. We sat down with her to talk about the book's theme's of slavery, freedom and guilt; and to discuss how much progress has really been made for black people in America and elsewhere since abolition.
Lawrence P. Jackson: 2018 National Book Festival
Lawrence P. Jackson discusses "Chester B. Himes: A Biography" at the 2018 Library of Congress National Book Festival in Washington, D.C.
Speaker Biography: Lawrence P. Jackson is the award-winning author of "Chester B. Himes: A Biography" (Norton), a finalist for the NAACP Image Award and the Edgar Award for Biography. A native of Baltimore, Jackson is a prominent historian known for his scholarship on African-American culture and literature. In addition to his highly praised biography of Himes, Jackson has written numerous books that explore African-American narratives: "My Father's Name: A Black Virginia Family after the Civil War," "The Indignant Generation: A Narrative History of African American Writers and Critics" and "Ralph Ellison: Emergence of Genius, 1913-1952." Jackson's forthcoming book is a collection of essays, "Christmas in Baltimore." He is the Bloomberg Distinguished Professor of English and History at John Hopkins University.
Nomi Prins: "Collusion: How Central Bankers Rigged the World" | Talks at Google
From a former Wall Street insider and author of All the Presidents' Bankers, a searing exposé of the collusion between public and private banks as they seek to control global markets and dictate economic policy. Central banks and institutions like the IMF and the World Bank are overstepping the boundaries of their mandates by using the flow of money to control global markets and dictate economic policy both at the domestic and global level. These public institutions have become so dependent on funding from private banking and the revolving door between the two worlds is so smooth that public and private banks are effectively working toward the same goals.
The Pushcart Prize XLIII - Best of the Small Presses 2019
The Writers Studio, in partnership with The Strand Bookstore, is pleased to present The Pushcart Prize XLIII - Best of the Small Presses 2019. Published every year since 1976, The Pushcart Prize is the most honored literary project in America, featuring hundreds of presses and writers of short stories, poetry, and essays in its annual collections.
Come together and connect with our writers' community, with readings by:
Cortney Lamar Charleston
Rick Moody
Thylias Moss
Oliver de la Paz
Marisa Silver
Introduction by founder/editor Bill Henderson.
Cortney Lamar Charleston is the author of Telepathologies, selected by D.A. Powell for the 2016 Saturnalia Books Poetry Prize. He was awarded a 2017 Ruth Lilly and Dorothy Sargent Rosenberg Fellowship from the Poetry Foundation and he has also received fellowships from Cave Canem, The Conversation Literary Festival and the New Jersey State Council on the Arts. His poems have appeared, or are forthcoming, in POETRY, The American Poetry Review, New England Review, AGNI, TriQuarterly and elsewhere. He serves as a poetry editor at The Rumpus.
Rick Moody is the author of The Ice Storm, Demonology, Hotels of North America, and many other books. He writes about music at The Rumpus and has an advice column at LitHub.
Thylias Moss, prize-winning multiracial maker, has won a number of awards beginning in 1983 with her poem, "Coming of Age in Sandusky," for which she received $25.00 from the Cleveland, Ohio Public Library. Since then, she has authored a total of 15 books, most of which have won awards, notably, a MacArthur Genius Fellowship, and two finalist awards from the National Book Critics Circle Award. She will be featuring her novel in verse, Slave Moth written by a literate slave girl, "Varl," a collection she needed to make after a visit to her son's middle school, a trip that necessitated her making the dress on the cover, by hand in the dark.
Oliver de la Paz is the author of three collections of poetry, most recently Requiem for the Orchard, winner of the Akron Prize for Poetry. His honors include a 2005 New York Foundation for the Arts Fellowship Award and a 2009 GAP Grant from Artist Trust. His work has appeared in literary journals and magazines including Virginia Quarterly Review, North American Review, Tin House, Chattahoochee Review, and in anthologies such as Asian American Poetry: The Next Generation.
Marisa Silver is the author of four novels, including Little Nothing and Mary Coin, and two collections of short stories. In 2017, she was awarded a Guggenheim Fellowship. Her work has received the Ohioana Book Prize, the Southern California Independent Bookseller Award, and the O. Henry Award. Her short fiction has been published in the New Yorker, as well as other journals, and has been included in The Best American Short Stories and other anthologies. She is a 2018-19 New York Public Library Mary Ellen von der Heyden Fellow during which time she'll be working on a new novel, The Mysteries.
Founded in 1987 by Pulitzer Prize winning poet Philip Schultz, The Writers Studio is an independent creative writing program, offering six and eight-week workshops specializing in topics from the necessity of political fiction to writers beginning in their fifties. The classes, which meet in New York City, San Francisco, Tucson, the Hudson Valley and Online utilize an original teaching method which combines technique-based instruction with personal weekly feedback. Since its inception in 1990, The Writers Studio Reading Series has featured numerous writers and poets, including Lydia Davis, Junot Diaz, Andre Dubus III, Jennifer Egan, Mary Gaitskill, Julia Glass, Edward Hirsch, A.M. Homes, Etgar Keret, Marie Ponsot, Robert Pinsky, Gary Shteyngart, Colson Whitehead, and Yehuda Amichai. www.writerstudio.com
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text: Hi all, I am running 8-node LAM/MPI parallel computing system. I found it's trouble to maintain the user accounts and software distribution on all the nodes. For example, whenever I install a new software , I have to repeat the job 8 times! The most annoying thing is that the configuration or managment of the user accounts over the network is a heavy job. Someone suggests that I should utilize NFS and NIS. However, in my case, it's difficult to have an additional computer as a server. Would anyone please share your experience in maintaining the beowulf cluster? Thanks in advance.


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