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The cosmetics have always been linked to the female sector, but since they became in one of the most important aspects of daily care for our health and wellbeing, they are also important for men. Shaving, the beard, pollution and a lack of hydration are factors that influence the appearance and health of the male skin. Nowadays there is a wide variety of products and types of cosmetics everyday more extensive. Perfume's Club wants to help you know what are those products suitable for your skin type and age. We present you several guidelines and tips that will help you establish a cosmetic routine that will improve your image as well as will help the health of your skin.
The first thing to consider is the type of skin you have in relation to the products that we will apply to ourselves: oil-free cosmetics if you have an oily skin, alcohol-free cosmetics if it is too dry, etc. The next thing that you have to consider is the age of your skin in order to know what are those products that better suit the current situation of your skin, as well as your goals: tone, brighten, enhance...
To achieve a most fresh and natural look, you will have to consider the possibility of having the best shaving creams and aftershaves for your face. And to mitigate all the imperfections and possible damages caused by shaving, don't forget to always have a good exfoliator, tonic or serum.
Each skin is different and not all the skin types accept in the same way the different cosmetics that we will use, so first of all it is important to know what is the type of skin that we possess. There are five skin types:
Knowing how to apply the cosmetics properly is not an easy task, but if you know how to do it you'll be able to make the most of your products and accomplish more visible effects on your skin. In general, both for the face and the body, there are some essential guidelines, since in this case the order of the factors may alter our result.
The first thing it will be cleanse well the area where we are going to work before applying anything. Then, if necessary, we will exfoliate and tone the skin well, to finally apply the moisturizer. Finally, if your skin is sensitive or you are just going to spend hours exposed to the sun, it is advisable applying sunscreen always at the end of the whole process.
With this you have the basic steps to follow a good skin care routine that will help you show the best side of your skin.
In the same way that the skin is important, so is knowing what are the basic ingredients of the cosmetics that we are going to apply to our skin and what are the active ingredients that will allow us to get the results we desire.
In the overall composition of the cosmetics, we can distinguish: the active ingredient, the excipient, preservatives, dyes, fragrances and correctors.
Choosing the cosmetics we like is important because they usually end up becoming our sign of identity, and even more the way we use them. This will reflect greater efficiency in our skin and will make us have a fresh and differentiated appearance.
Don't hesitate to always choose those products that are more beneficial to the parts of the face or body that you want to enhance. To do this, we'll give you some tips you can follow when making your decision:
Following these tips and guidelines when you go to choose and use your cosmetics, we assure you that you will be able to achieve a fresh and neat beauty.


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FSFE Newsletter – January 2014
From Yuletide to Full-Blown Winter
Many hackers (including us, of course!) have been enjoying the various festivities occurring around the winter solstice. But, alas!, the time to dwell on Christmas presents and enjoy a family recess is no more – the Yule has gone, the year has been made anew, and the fight for freedom and liberty demands our attention once more. Hence, it is only fitting to begin with a short review of what 2014 has got in store for us during the next few months.
Those fond of celebrations should already have their eyes set on February 14, the yearly occasion when our website turns pink and heart-laden, and the perfect time to hug developers and bring loved ones to Free Software and the Fellowship.
Those favouring a more hands-on approach have to wait until late March to educate their fellow citizens about Open Standards. However, it is not necessary to despair: our various ongoing campaigns are always looking for new hacktivists. Getting in touch is easy!
And while we are on the topic, there will be many opportunities to meet our staff, volunteers, and Fellows throughout the year. For starters, FSFE is going to be present with a booth at the Free Software conference FOSDEM, which takes place on the first weekend of February at Brussels. Everyone fancying a chat or running low on freedom gear should stop by. Those who cannot make it to FOSDEM this year should occasionally check the events section on our website for future opportunities to meet us.
Do It Yourself versus Digital Restrictions Management
While we are sure that many of our readers were either lucky or vocal enough to only receive Christmas presents that respect their freedom, there are probably some who find themselves in possession of items that were neither made by the giver nor appear in our sister's Holiday Giving Guide.
We have a few recommendations for handling such gifts: some of those can be liberated (e.g., Android devices); developers working to create free replacements to various proprietary systems would most likely appreciate hardware donations (search the web for various efforts to liberate various device categories); and you might be able to hack such a gift to run Free Software.
Whatever you have decided to do with such items, we would love to hear about your solutions. We have opened a mailing list thread on the topic and e-mails to firstname.lastname@example.com (please be advised this is a public mailing list) are most welcome. In addition to solutions to non-free gifts, we are also looking forward to reading about freedom-respecting or DIY gifts you are truly enjoying.
Something Completely Different
- This newsletter is regularly available in Romanian since December 2013 . Our associate Fundația Ceata has taken it upon themselves to provide timely translations for which we are extremely grateful.
- From the planet aggregation:
- Our ex-Vice President Henrik Sandklef has been busy adding LCD support to Searduino. The latter post (not on the planet) also serves as a call for contributors.
- Isabel Drost-Fromm's 'On geeks growing up' contemplates the meaning of life, or to put it more plainly, family-friendliness of various technology conferences. The positive role models Isabel has identified deserve a few words of encouragement, and to Isabel herself we say naught but Inductive Bias rocks!
- Guido Arnold, Deputy Coordinator of the Education team, has collected and summarised November news stories about Free Software in education.
- Daniel Pocock has written extensively about WebRTC ('Free calling from browser to mobile with free software', 'Get WebRTC going faster', 'xWiki: 10 years and a WebRTC success story').
- Paul Boddie has done the same about Kolab ('Adventures in Kolab Packaging and pykolab', 'Integrating setup-kolab with Debian Packaging').
- The last planet item to warrant an honourable mention in the newsletter under this temporary editorship is Jens Lechtenbörger's 'OpenPGP and S/MIME or Trust and "Trust"'. Jens explains why OpenPGP should be preferred over S/MIME for e-mail encryption. Acquainting oneself with the explanation is highly recommended for anyone making use of, or contemplating the use of, e-mail encryption.
- Repentinus, one of our two Fellowship Representatives, is keeping his neck warm this winter by wearing a green-black woollen scarf featuring the Fellowship Plussy and letters "FSFE". Those among our readers who can knit can make themselves a similar scarf by following the instructions provided by his girlfriend (please be advised this link leads to a blog hosted on Blogspot; taking appropriate precautions (like using a JavaScript blocker) is recommended). The rest of our readers can either learn to knit or have someone knit this scarf for them.
Giving for Freedom
This newsletter started with a short overview of annual events waiting us in the next few months. Such celebrations, while fun and educational, require the combined efforts of volunteers and our staff to organise. In addition to requiring staff time, activities hosted as part of the celebrations require funds. Furthermore, in addition to the fun celebrations, we require funds to keep our continuous campaigns running, lobby for Free Software, advise developers on Free Software licensing, and educate technology companies on Free Software and licence compliance. Unfortunately, we have not yet secured our budget for 2014. Our readers considering supporting our work can either make a one-time donation or join the Fellowship. We thank all our existing donors and Fellows!
Free New Year!
Heiki Ojasild -


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Thirty-two asylum seekers rescued by the Sri Lankan navy say they went without food for 21 days and were forced to throw dozens of dead overboard after their wooden vessel failed at sea. The survivors, who identified themselves as Muslims from near the Burma-Bangladesh border, told local officials that they set out to seek refuge in Indonesia or Australia, but instead spent two months languishing on the water. By the time they were plucked from the sea, they'd thrown 98 bodies to the waves.
The nightmare of shipwreck may sound like a relic of another time, but what happened off the coast of Sri Lanka this week is alarmingly commonplace. The U.N. estimates that at least 13,000 people fled the borderlands between Burma and Bangladesh by boat in 2012. Of them, 485 are known to have drowned. This deadly tide looks unlikely to recede: at least 1,800 refugees washed up in Thailand in January 2013 alone.
(MORE: On Its Treatment on Minorities, Burma Has a Long Way to Go)
Why risk the waves? Many of the asylum seekers are ethnic Rohingya Muslims, a group the U.N. identifies as among the most isolated and oppressed in the world. Though many Rohingya have lived along the Bay of Bengal for generations, some 800,000 are stateless, sandwiched between Burma and Bangladesh, welcome in neither. The Burmese government has never recognized them as part of the patchwork nation's 135 indigenous ethnic groups and, over the years, has restricted their right to live, work and marry. In June 2012, the reported rape of a Buddhist woman in Arakan (Rakhine) state sparked a wave of communal violence that left at least 78 dead and tens of thousands displaced. An August report by Human Rights Watch said Burmese security forces did little to stop the violence and committed acts of murder, rape and forced displacement.
In the months since that violence, the conflict has lingered on, with many ethnic Rohingya left to wait indefinitely in squalid camps. In a dispatch published yesterday, TIME contributor Jason Motlagh, outlined how conditions have deteriorated:
Eight months on, pockets of Rohingya that remain in rural Arakan state are in serious trouble. Doctors Without Borders (MSF) announced in early February that its field teams continued to face hostile threats from Arakanese leaders and state forces that forced them to cut back medical care. Moreover, the aid agency warned of a brewing "humanitarian emergency" in the heavily restricted camps around Sittwe. Burmese officials claim the camps are necessary to shield the Rohingya population from further harm, but MSF says that acute malnutrition, skin infections and other ailments caused by poor sanitation are on the rise, especially among those uprooted by a second spasm of violence in October and now live on the margins of established camps.
With few options for work, and limited prospects for peace, more and more people are fleeing, Motlagh writes:
Faced with stagnant conditions inside the camps and insecurity everywhere else, greater numbers are taking their chances on the open sea. Mohdi Kasim, a prominent Rohingya community leader living in one of the camps, described how his neighbor, a veteran police officer, showed up at his door earlier in the morning in tears asking for money to help cover his boat fare. Both of his sons had already left. According to Idriss, 35, a Rohingya boat builder with gold rings on his fingers, two to three vessels are leaving the Sittwe area every night, often packed with over 100 passengers. (He declines to disclose his full name for fear of persecution.) "We tell the people it's not safe, but they insist on going," he says. "They are suffering so much here." (Read the full story: "Pushed From Burma, Stateless Rohingya Flee by Boat")
Until that pain eases, desperate people will take to the water, and the death toll will rise.


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Cartoon Amanda Girl Canvas Print
Print featuring a watercolor illustration of a girl. Add a stylish touch to your interior with this beautiful fine art prints.
The Cartoon Amanda Girl Canvas Print is a perfect eye catchers for your gallery wall. Create your own style gallery with a plethora of styles from our Art Prints and Posters collection.
This wall art decor is printed on high quality cotton canvas using UV sprayed ink for a more realistic look. The poster is not framed, but it can be easily installed on any frame of your chosen size.
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- Frame not included
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- Available in a large variety of sizes.
We offer professional packaging on our products, so you will receive it in the best condition.
Product Details
Product Details
Fine Art Canvas Print (Unframed)
All measurements for this product are in cm's.
Delivery & Returns
Delivery & Returns
We offer free shipping on all orders to over 170 countries worldwide. Our primary goal is to offer exceptional value and service to our customers, striving to exceed expectations by continually expanding and adapting to meet the diverse needs of our clientele across the globe.
Do you ship worldwide?
Absolutely. We offer FREE shipping to more than 170 countries globally. Nonetheless, there are certain locations we cannot deliver to. In the event that your location falls within this category, we will reach out to you once we receive your order.
How do you ship packages?
Our canvas prints are shipped via postal services around the world in solid tubes to safeguard the canvas during transportation. Packages in the USA are shipped primarily by USPS and in Canada via Canada Post. Our shipments across mainland Europe are handled by Deutsche Post, DHL, PostNL. Packages in Australia and Singapore are handled by Australia Post and Singapore Post. Packages in New Zealand are shipped by New Zealand Post. Some orders may be shipped via DHL or FedEx, depending on the weight and size of the package.
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Most orders are arriving within 10-20 Business Days, depending on your location. Here are the estimated shipping timeframes we provide:
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*Kindly allocate 3-5 days for order processing.
Do you provide tracking information?
Yes, we provide tracking information. Soon after your order ships, you will receive an email that contains your tracking information.
- Free shipping to certain destinations may not provide tracking information until the package is close to its final delivery point.
- Some shipping carriers may take approximately 5-7 business days for tracking information to reflect in our system.
- Items from the same purchase may be sent in separate packages due to logistical considerations.
- Some international shipments may experience extended intervals between tracking updates, spanning several days or even weeks, as packages move through various postal distribution centers en route to their destinations.
What should I consider regarding customs when making an international purchase?
We ship internationally, and although the majority of our customers experience no duties or taxes, there is a possibility of a minor import duty based on your country. After the items have been shipped, any custom fees are beyond our responsibility. When you purchase our products, you acknowledge that one or more packages may be shipped to you, potentially incurring custom fees upon arrival in your country.
Delivery Update. Please be informed that until further notice, we are unable to ship to the following countries due to existing limitations in international logistics: India and South Africa.
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For more information in our Refund Policy at Diveros
This product is shipped in a rigid tube for protection of the canvas in transit.


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Le Parfum Intense EDP
Le Parfum Intense is an amazing perfume when you like to dress in a new style.
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Iontophoresis Protocol: Low Back Pain
Most individuals will be affected by back pain at some point in their life. As many as 8 of 10 Americans will have a back injury sometime during their lifetime. Back pain accounts for many lost days from family, work, and untold pain. Low back pain may be caused by: soft tissue irritation from muscle, tendon or fascia irritation, the facet joint (synovial membrane, capsule), the anterior and/or posterior vertebral ligaments, the intervertebral disc, the dura mater or dura! sleeve, the nerve root, or the bone. These irritants can be caused primarily by trauma, repetitive motions, internal stressors, or any combination.
Careful evaluation must be carried out by the practitioner to determine which exact tissue is implicated. Additionally, pain can be referred to the back from other structures or conditions such as from the viscera (reproductive system. urinary system) vessels (occlusion of iliac arteries, aortic aneurysm), the neural system (arachnoiditis, infections of the neural tissue, neoplasms) or systemic disorders (osteoporosis, rheumatoid arthritis, ankylosing spondylitis). Evaluation and careful screening are required before treatment can be successfully carried out. Treatment of low back pain is multifaceted and usually involves several treatment modalities depending on the severity of the injury. The ultimate goal of treatment is to restore full function of the individual.


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Mission statement and aims
As a part of its strategy with the Digital Library the Austrian National Library has given itself these aims:
- To build up digital collections consisting of digitised and "born digital" resources.
- To conform to international standards in management of digital collections.
- To give access to these digital collections to scholars and the broader public with the appropriate interfaces, meanwhile respecting the wishes of users and the legal requirements.
- To store these digital collections in long-term archives, since they are part of the cultural heritage of Austria.
- To make the offerings of the library known to the public, so as to aid in the development of an informed society in Austria, to offer democratic and egalitarian access to information, and to encourage life-long learning.
- To conduct research and development at international and national levels, to introduce technologies of textual recognition and search engines, to optimise strategies of long-term archiving, and to improve digital services.
Digital Library Main Department
Main Department DirectorMag. Bettina Kann
Josefsplatz 1
A-1015 Wien
(+43 1) 534 10-448
last update


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Health Ranger Report – 30th Dec, 2020
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NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency.
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We've finished preparing your site for you. Here are the next steps:
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Update the site's environment
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Forge has wonderful documentation. Whether you're new or have previous experience, we recommend reading all of the documentation from beginning to end.
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Laracasts has a comprehensive and free video course on Forge. Feel free to review this course if you are new to Laravel Forge and want a video overview of its features.
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Development Co-operation Report 2017
Data for Development
The 2017 volume of the Development Co-operation Report focuses on Data for Development. "Big Data" and "the Internet of Things" are more than buzzwords: the data revolution is transforming the way that economies and societies are functioning across the planet. The Sustainable Development Goals along with the data revolution are opportunities that should not be missed: more and better data can help boost inclusive growth, fight inequalities and combat climate change. These data are also essential to measure and monitor progress against the Sustainable Development Goals.
The value of data in enabling development is uncontested. Yet, there continue to be worrying gaps in basic data about people and the planet and weak capacity in developing countries to produce the data that policy makers need to deliver reforms and policies that achieve real, visible and long-lasting development results. At the same time, investing in building statistical capacity – which represented about 0.30% of ODA in 2015 – is not a priority for most providers of development assistance.
There is a need for stronger political leadership, greater investment and more collective action to bridge the data divide for development. With the unfolding data revolution, developing countries and donors have a unique chance to act now to boost data production and use for the benefit of citizens. This report sets out priority actions and good practices that will help policy makers and providers of development assistance to bridge the global data divide, notably by strengthening statistical systems in developing countries to produce better data for better policies and better lives.
Also available in: French
Share of bilateral ODA by sector, 2014-15 average, commitments, Norway
Also available in: French
- Click to access:
Click to download XLSXLS


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text: Fig. 12. VICTORY CROWNING A HERO. In the Pinakothek at Munich. After a photograph from the original by Franz Hanfstängl, Munich. (To page 22.) male and female heads drawn from the antique, with studies for folded hands on the same sheat (Fig. 7). Side by side with these vigorous drawings, we should also mention the noble sketch of an old man with a beard, which probably served as a model for some holy bishop and well illustrates the method employed by the young Rubens in his studies from life (Fig. 8). In 1603 he was sent to Spain by the Duke of Mantua. It seems that he considered the artist the fittest personage to deliver certain presents intended for King Philip III. and his minister the Duke of Lerma. The voyage was not favoured with fine weather, for it rained uncessantly for twenty days. Only a portion of the gifts, which included a carriage with seven Neapolitan horses, could be delivered uninjured; whilst the other part with the pictures painted by Rubens for the Spanish court were entirely ruined through the rain. The proposal of the Mantuan Ambassador that the pictures should be restored with the assistance of some Spanish painter, was firmly rejected by Rubens who declared, "that he did not choose to be associated with any one else". The circumstance that the interview with the King was delayed, enabled him however not only with his own hands to restore his damaged pictures, but also to paint two new ones:— Heraclitus and Democritus, the Weeping and the Laughing Philosophers; which two pictures are still in the Madrid Gallery. After he had accomplished his mission to the King of Spain he was employed until the following autumn by the Duke of Lerma, of whom he painted an equestrian portrait, besides thirteen single figures: Christ and his Twelve Apostles. These last are also still in the Madrid Gallery, but the figure of Christ himself has disappeared. Later replicas of these thirteen pictures are to be found at the Palazzo Rospigliosi in Rome, while a number of drawings for them are in the Albertina at Vienna (Fig. 9). The excellent portrait of a Franciscan priest, now in the Munich Pinakothek, is said also to have been painted in Spain (Fig. 10). At the beginning of 1604 Rubens returned to Mantua, where his chief work during that and the following year as the completion of a triptych for the Jesuit-Church. The centre-piece represented the Trinity, the two wings the Baptism and Transfiguration of Christ. At the taking of Mantua by the French in 1797 these three pictures were carried away; but the centreportion divided into two portions was subsequently brought back, and is now in the Public Library. The Transfiguration is in the Museum at Nancy, while the Baptism, much repainted, found its way in 1876 to the Gallery of Antwerp. In the year 1605 the Emperor Rudolf II. commissioned Rubens to copy two pictures by Correggio. In 1606 he was again in Rome, where he began to paint an altar-piece for an Oratory just built, known as the new church (Chiesa Nuova). Before, however, he could finish it, he was recalled by the Duke of Mantua, in whose company in the following year he went to Genoa. Here he devoted special attention to the architecture of the town and, in order to improve the taste for building in his own country, conceived the idea, of making a collection of drawings of Genoese palace-architecture. This plan he subsequently carried out in conjunction with N. Rykemans; and a collection of etchings, including no less than 136 plates of the "Palazzi di Genova", appeared at Antwerp in two separate Fig. 13. THE RIVERGOD TIBER (OR TIGRIS) WITH THE GODDESS OF PLENTY. In the Hermitage at St. Petersburg. After a photograph from the original by Braun, Clément & Co., Dornach, Paris and New-York. (To page 22.) parts in the years 1613 and 1622 respectively. 1622 respectively. For the Jesuit-church (St. Ambrogio) at Genoa he painted - it is uncertain when-two altarpieces: the Circumcision and St. Ignatius healing a Demoniac and restoring to life Dead Children. This latter, which is very large, is a splendid work. Fig. 14. RUBENS AND HIS WIFE ISABELLA BRANT. In the Pinakothek at Munich. Whilst in Milan on his return from Genoa and also when on his way to Spain, Rubens made careful drawings from Leonardo's "Battle of Anghiari" and from the celebrated Cena, both of which are preserved in the Louvre. It is also probable that he painted in the same city, in order to rival Leonardo, the Lord's Supper which is now in the Brera Collection. |


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Label: GLIPIZIDE tablet
- NDC Code(s): 70934-666-30, 70934-666-60, 70934-666-90
- Packager: Denton Pharma, Inc. dba Northwind Pharmaceuticals
- This is a repackaged label.
- Source NDC Code(s): 60505-0141
- Category: HUMAN PRESCRIPTION DRUG LABEL
- DEA Schedule: None
- Marketing Status: Abbreviated New Drug Application
Drug Label Information
Updated January 1, 2023
If you are a consumer or patient please visit this version.
- Download DRUG LABEL INFO: PDF XML
- Official Label (Printer Friendly)
Glipizide is an oral blood-glucose-lowering drug of the sulfonylurea class.
The Chemical Abstracts name of glipizide is 1-cyclohexyl-3-[[p-[2-(5-methylpyrazine-carboxamido)ethyl]phenyl]sulfonyl]urea. The molecular formula is C 21H 27N 5O 4S; the molecular weight is 445.55; the structural formula is shown below:
Glipizide is a whitish, odorless powder with a pKa of 5.9. It is insoluble in water and alcohols, but soluble in 0.1 N NaOH; it is freely soluble in dimethylformamide. Glipizide tablets, USP for oral use are available in 5 and 10 mg strengths.
Inert ingredients are: anhydrous lactose; colloidal silicon dioxide; magnesium stearate; sodium starch glycolate.
Meets USP Dissolution Test 2.
Mechanism of Action
The primary mode of action of glipizide in experimental animals appears to be the stimulation of insulin secretion from the beta cells of pancreatic islet tissue and is thus dependent on functioning beta cells in the pancreatic islets. In humans, glipizide appears to lower the blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets. The mechanism by which glipizide lowers blood glucose during long-term administration has not been clearly established. In man, stimulation of insulin secretion by glipizide in response to a meal is undoubtedly of major importance. Fasting insulin levels are not elevated even on long-term glipizide administration, but the postprandial insulin response continues to be enhanced after at least 6 months of treatment. The insulinotropic response to a meal occurs within 30 minutes after an oral dose of glipizide in diabetic patients, but elevated insulin levels do not persist beyond the time of the meal challenge. Extrapancreatic effects may play a part in the mechanism of action of oral sulfonylurea hypoglycemic drugs.
Blood sugar control persists in some patients for up to 24 hours after a single dose of glipizide, even though plasma levels have declined to a small fraction of peak levels by that time (see Pharmacokinetics below).
Some patients fail to respond initially, or gradually lose their responsiveness to sulfonylurea drugs, including glipizide. Alternatively, glipizide may be effective in some patients who have not responded or have ceased to respond to other sulfonylureas.
Other Effects
It has been shown that glipizide therapy was effective in controlling blood sugar without deleterious changes in the plasma lipoprotein profiles of patients treated for NIDDM.
In a placebo-controlled, crossover study in normal volunteers, glipizide had no antidiuretic activity and, in fact, led to a slight increase in free water clearance.
Gastrointestinal absorption of glipizide in man is uniform, rapid, and essentially complete. Peak plasma concentrations occur 1 to 3 hours after a single oral dose. The half-life of elimination ranges from 2 to 4 hours in normal subjects, whether given intravenously or orally. The metabolic and excretory patterns are similar with the two routes of administration, indicating that first-pass metabolism is not significant. Glipizide does not accumulate in plasma on repeated oral administration. Total absorption and disposition of an oral dose was unaffected by food in normal volunteers, but absorption was delayed by about 40 minutes. Thus, glipizide was more effective when administered about 30 minutes before, rather than with, a test meal in diabetic patients. Protein binding was studied in serum from volunteers who received either oral or intravenous glipizide and found to be 98 to 99% one hour after either route of administration. The apparent volume of distribution of glipizide after intravenous administration was 11 liters, indicative of localization within the extracellular fluid compartment. In mice, no glipizide or metabolites were detectable autoradiographically in the brain or spinal cord of males or females, nor in the fetuses of pregnant females. In another study, however, very small amounts of radioactivity were detected in the fetuses of rats given labeled drug.
The metabolism of glipizide is extensive and occurs mainly in the liver. The primary metabolites are inactive hydroxylation products and polar conjugates and are excreted mainly in the urine. Less than 10% unchanged glipizide is found in the urine.
The administration of oral hypoglycemic drugs has been reported to be associated with increased cardiovascular mortality as compared to treatment with diet alone or diet plus insulin. This warning is based on the study conducted by the University Group Diabetes Program (UGDP), a long-term prospective clinical trial designed to evaluate the effectiveness of glucose-lowering drugs in preventing or delaying vascular complications in patients with non-insulin-dependent diabetes. The study involved 823 patients who were randomly assigned to one of four treatment groups (Diabetes, 19, supp. 2: 747-830, 1970). UGDP reported that patients treated for 5 to 8 years with diet plus a fixed dose of tolbutamide (1.5 grams per day) had a rate of cardiovascular mortality approximately 2 1/ 2 times that of patients treated with diet alone. A significant increase in total mortality was not observed, but the use of tolbutamide was discontinued based on the increase in cardiovascular mortality, thus limiting the opportunity for the study to show an increase in overall mortality. Despite controversy regarding the interpretation of these results, the findings of the UGDP study provide an adequate basis for this warning. The patient should be informed of the potential risks and advantages of glipizide and of alternative modes of therapy.
Although only one drug in the sulfonylurea class (tolbutamide) was included in this study, it is prudent from a safety standpoint to consider that this warning may also apply to other oral hypoglycemic drugs in this class, in view of their close similarities in mode of action and chemical structure.
Macrovascular Outcomes
There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with glipizide or any other anti-diabetic drug.
Renal and Hepatic Disease
The metabolism and excretion of glipizide may be slowed in patients with impaired renal and/or hepatic function. If hypoglycemia should occur in such patients, it may be prolonged and appropriate management should be instituted.
All sulfonylurea drugs are capable of producing severe hypoglycemia. Proper patient selection, dosage, and instructions are important to avoid hypoglycemic episodes. Renal or hepatic insufficiency may cause elevated blood levels of glipizide and the latter may also diminish gluconeogenic capacity, both of which increase the risk of serious hypoglycemic reactions. Elderly, debilitated or malnourished patients, and those with adrenal or pituitary insufficiency, are particularly susceptible to the hypoglycemic action of glucose-lowering drugs. Hypoglycemia may be difficult to recognize in the elderly, and in people who are taking beta-adrenergic blocking drugs. Hypoglycemia is more likely to occur when caloric intake is deficient, after severe or prolonged exercise, when alcohol is ingested, or when more than one glucose-lowering drug is used.
Loss of Control of Blood Glucose
When a patient stabilized on any diabetic regimen is exposed to stress such as fever, trauma, infection, or surgery, a loss of control may occur. At such times, it may be necessary to discontinue glipizide and administer insulin.
The effectiveness of any oral hypoglycemic drug, including glipizide, in lowering blood glucose to a desired level decreases in many patients over a period of time, which may be due to progression of the severity of the diabetes or to diminished responsiveness to the drug. This phenomenon is known as secondary failure, to distinguish it from primary failure in which the drug is ineffective in an individual patient when first given.
Hemolytic Anemia
Treatment of patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency with sulfonylurea agents can lead to hemolytic anemia. Because glipizide belongs to the class of sulfonylurea agents, caution should be used in patients with G6PD deficiency and a non-sulfonylurea alternative should be considered. In post-marketing reports, hemolytic anemia has also been reported in patients who did not have known G6PD deficiency.
Laboratory Tests
Blood and urine glucose should be monitored periodically. Measurement of glycosylated hemoglobin may be useful.
Information for Patients
Patients should be informed of the potential risks and advantages of glipizide and of alternative modes of therapy. They should also be informed about the importance of adhering to dietary instructions, of a regular exercise program, and of regular testing of urine and/or blood glucose.
The risks of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development should be explained to patients and responsible family members. Primary and secondary failure should also be explained.
Physician Counseling Information for Patients
In initiating treatment for type 2 diabetes, diet should be emphasized as the primary form of treatment. Caloric restriction and weight loss are essential in the obese diabetic patient. Proper dietary management alone may be effective in controlling the blood glucose and symptoms of hyperglycemia. The importance of regular physical activity should also be stressed, and cardiovascular risk factors should be identified and corrective measures taken where possible. Use of glipizide or other antidiabetic medications must be viewed by both the physician and patient as a treatment in addition to diet and not as a substitution or as a convenient mechanism for avoiding dietary restraint. Furthermore, loss of blood glucose control on diet alone may be transient, thus requiring only short-term administration of glipizide or other antidiabetic medications. Maintenance or discontinuation of glipizide or other antidiabetic medications should be based on clinical judgment using regular clinical and laboratory evaluations.
Drug Interactions
The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, quinolones and beta adrenergic blocking agents. When such drugs are administered to a patient receiving glipizide, the patient should be observed closely for hypoglycemia. When such drugs are withdrawn from a patient receiving glipizide, the patient should be observed closely for loss of control. In vitro binding studies with human serum proteins indicate that glipizide binds differently than tolbutamide and does not interact with salicylate or dicumarol. However, caution must be exercised in extrapolating these findings to the clinical situation and in the use of glipizide with these drugs.
Certain drugs tend to produce hyperglycemia and may lead to loss of control. These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. When such drugs are administered to a patient receiving glipizide, the patient should be closely observed for loss of control. When such drugs are withdrawn from a patient receiving glipizide, the patient should be observed closely for hypoglycemia.
A potential interaction between oral miconazole and oral hypoglycemic agents leading to severe hypoglycemia has been reported. Whether this interaction also occurs with the intravenous, topical, or vaginal preparations of miconazole is not known. The effect of concomitant administration of fluconazole and glipizide has been demonstrated in a placebo-controlled crossover study in normal volunteers. All subjects received glipizide alone and following treatment with 100 mg of fluconazole as a single daily oral dose for 7 days. The mean percentage increase in the glipizide AUC after fluconazole administration was 56.9% (range: 35 to 81).
In studies assessing the effect of colesevelam on the pharmacokinetics of glipizide ER in healthy volunteers, reductions in glipizide AUC 0-∞ and C max of 12% and 13%, respectively were observed when colesevelam was coadministered with glipizide ER. When glipizide ER was administered 4 hours prior to colesevelam, there was no significant change in glipizide AUC 0-∞ or C max, -4% and 0%, respectively. Therefore, glipizide should be administered at least 4 hours prior to colesevelam to ensure that colesevelam does not reduce the absorption of glipizide.
Carcinogenesis, Mutagenesis, Impairment of Fertility
A twenty month study in rats and an eighteen month study in mice at doses up to 75 times the maximum human dose revealed no evidence of drug-related carcinogenicity. Bacterial and in vivo mutagenicity tests were uniformly negative. Studies in rats of both sexes at doses up to 75 times the human dose showed no effects on fertility.
Pregnancy Category C
Glipizide was found to be mildly fetotoxic in rat reproductive studies at all dose levels (5 to 50 mg/kg). This fetotoxicity has been similarly noted with other sulfonylureas, such as tolbutamide and tolazamide. The effect is perinatal and believed to be directly related to the pharmacologic (hypoglycemic) action of glipizide. In studies in rats and rabbits, no teratogenic effects were found. There are no adequate and well controlled studies in pregnant women. Glipizide should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Because recent information suggests that abnormal blood glucose levels during pregnancy are associated with a higher incidence of congenital abnormalities, many experts recommend that insulin be used during pregnancy to maintain blood glucose levels as close to normal as possible.
Nonteratogenic Effects
Prolonged severe hypoglycemia (4 to 10 days) has been reported in neonates born to mothers who were receiving a sulfonylurea drug at the time of delivery. This has been reported more frequently with the use of agents with prolonged half-lives. If glipizide is used during pregnancy, it should be discontinued at least one month before the expected delivery date.
Nursing Mothers
Although it is not known whether glipizide is excreted in human milk, some sulfonylurea drugs are known to be excreted in human milk. Because the potential for hypoglycemia in nursing infants may exist, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. If the drug is discontinued and if diet alone is inadequate for controlling blood glucose, insulin therapy should be considered.
Geriatric Use
A determination has not been made whether controlled clinical studies of glipizide included sufficient numbers of subjects aged 65 and over to define a difference in response from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
In U.S. and foreign controlled studies, the frequency of serious adverse reactions reported was very low. Of 702 patients, 11.8% reported adverse reactions and in only 1.5% was glipizide discontinued.
Gastrointestinal disturbances are the most common reactions. Gastrointestinal complaints were reported with the following approximate incidence: nausea and diarrhea, one in seventy; constipation and gastralgia, one in one hundred. They appear to be dose-related and may disappear on division or reduction of dosage. Cholestatic jaundice may occur rarely with sulfonylureas: glipizide should be discontinued if this occurs.
Allergic skin reactions including erythema, morbilliform or maculopapular eruptions, urticaria, pruritus, and eczema have been reported in about one in seventy patients. These may be transient and may disappear despite continued use of glipizide; if skin reactions persist, the drug should be discontinued. Porphyria cutanea tarda and photosensitivity reactions have been reported with sulfonylureas.
Leukopenia, agranulocytosis, thrombocytopenia, hemolytic anemia (see PRECAUTIONS), aplastic anemia, and pancytopenia have been reported with sulfonylureas.
Hepatic porphyria and disulfiram-like reactions have been reported with sulfonylureas. In the mouse, glipizide pretreatment did not cause an accumulation of acetaldehyde after ethanol administration. Clinical experience to date has shown that glipizide has an extremely low incidence of disulfiram-like alcohol reactions.
Endocrine Reactions
Cases of hyponatremia and the syndrome of inappropriate antidiuretic hormone (SIADH) secretion have been reported with this and other sulfonylureas.
Dizziness, drowsiness, and headache have each been reported in about one in fifty patients treated with glipizide. They are usually transient and seldom require discontinuance of therapy.
Laboratory Tests
The pattern of laboratory test abnormalities observed with glipizide was similar to that for other sulfonylureas. Occasional mild to moderate elevations of SGOT, LDH, alkaline phosphatase, BUN, and creatinine were noted. One case of jaundice was reported. The relationship of these abnormalities to glipizide is uncertain, and they have rarely been associated with clinical symptoms.
There is no well documented experience with glipizide overdosage. The acute oral toxicity was extremely low in all species tested (LD 50 greater than 4 g/kg).
Overdosage of sulfonylureas, including glipizide, can produce hypoglycemia. Mild hypoglycemic symptoms without loss of consciousness or neurologic findings should be treated aggressively with oral glucose and adjustments in drug dosage and/or meal patterns. Close monitoring should continue until the physician is assured that the patient is out of danger. Severe hypoglycemic reactions with coma, seizure, or other neurological impairment occur infrequently, but constitute medical emergencies requiring immediate hospitalization. If hypoglycemic coma is diagnosed or suspected, the patient should be given a rapid intravenous injection of concentrated (50%) glucose solution. This should be followed by a continuous infusion of a more dilute (10%) glucose solution at a rate that will maintain the blood glucose at a level above 100 mg/dL. Patients should be closely monitored for a minimum of 24 to 48 hours since hypoglycemia may recur after apparent clinical recovery. Clearance of glipizide from plasma would be prolonged in persons with liver disease. Because of the extensive protein binding of glipizide, dialysis is unlikely to be of benefit.
There is no fixed dosage regimen for the management of diabetes mellitus with glipizide or any other hypoglycemic agent. In addition to the usual monitoring of urinary glucose, the patient's blood glucose must also be monitored periodically to determine the minimum effective dose for the patient; to detect primary failure, i.e., inadequate lowering of blood glucose at the maximum recommended dose of medication; and to detect secondary failure, i.e., loss of an adequate blood-glucose-lowering response after an initial period of effectiveness. Glycosylated hemoglobin levels may also be of value in monitoring the patient's response to therapy.
Short-term administration of glipizide may be sufficient during periods of transient loss of control in patients usually controlled well on diet.
In general, glipizide tablets should be given approximately 30 minutes before a meal to achieve the greatest reduction in postprandial hyperglycemia.
Initial Dose
The recommended starting dose is 5 mg, given before breakfast. Geriatric patients or those with liver disease may be started on 2.5 mg.
Dosage adjustments should ordinarily be in increments of 2.5 to 5 mg, as determined by blood glucose response. At least several days should elapse between titration steps. If response to a single dose is not satisfactory, dividing that dose may prove effective. The maximum recommended once daily dose is 15 mg. Doses above 15 mg should ordinarily be divided and given before meals of adequate caloric content. The maximum recommended total daily dose is 40 mg.
Some patients may be effectively controlled on a once-a-day regimen, while others show better response with divided dosing. Total daily doses above 15 mg should ordinarily be divided. Total daily doses above 30 mg have been safely given on a b.i.d. basis to long-term patients.
In elderly patients, debilitated or malnourished patients, and patients with impaired renal or hepatic function, the initial and maintenance dosing should be conservative to avoid hypoglycemic reactions (see PRECAUTIONS section).
Patients Receiving Insulin
As with other sulfonylurea-class hypoglycemics, many stable non-insulin-dependent diabetic patients receiving insulin may be safely placed on glipizide. When transferring patients from insulin to glipizide, the following general guidelines should be considered:
For patients whose daily insulin requirement is 20 units or less, insulin may be discontinued and glipizide therapy may begin at usual dosages. Several days should elapse between glipizide titration steps.
For patients whose daily insulin requirement is greater than 20 units, the insulin dose should be reduced by 50% and glipizide therapy may begin at usual dosages. Subsequent reductions in insulin dosage should depend on individual patient response. Several days should elapse between glipizide titration steps.
During the insulin withdrawal period, the patient should test urine samples for sugar and ketone bodies at least three times daily. Patients should be instructed to contact the prescriber immediately if these tests are abnormal. In some cases, especially when patient has been receiving greater than 40 units of insulin daily, it may be advisable to consider hospitalization during the transition period.
Patients Receiving Other Oral Hypoglycemic Agents
As with other sulfonylurea-class hypoglycemics, no transition period is necessary when transferring patients to glipizide. Patients should be observed carefully (1 to 2 weeks) for hypoglycemia when being transferred from longer half-life sulfonylureas (e.g., chlorpropamide) to glipizide due to potential overlapping of drug effect.
When colesevelam is coadministered with glipizide ER, maximum plasma concentration and total exposure to glipizide is reduced. Therefore, glipizide should be administered at least 4 hours prior to colesevelam.
Store at 20˚C to 25˚C (68˚F to 77˚F) [see USP Controlled Room Temperature].
Dispense in a tight, light-resistant container [see USP].
5 mg and 10 mgManufactured by Manufactured for
Apotex Inc. Apotex Corp.
Toronto, Ontario Weston, Florida
Canada M9L 1T9 USA 33326Revised: May 2017
Rev. 8
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glipizide tabletProduct Information Product Type HUMAN PRESCRIPTION DRUG Item Code (Source) NDC:70934-666(NDC:60505-0141) Route of Administration ORAL Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength GLIPIZIDE (UNII: X7WDT95N5C) (GLIPIZIDE - UNII:X7WDT95N5C) GLIPIZIDE 5 mg Inactive Ingredients Ingredient Name Strength ANHYDROUS LACTOSE (UNII: 3SY5LH9PMK) SILICON DIOXIDE (UNII: ETJ7Z6XBU4) MAGNESIUM STEARATE (UNII: 70097M6I30) SODIUM STARCH GLYCOLATE TYPE A POTATO (UNII: 5856J3G2A2) Product Characteristics Color white Score 2 pieces Shape ROUND Size 6mm Flavor Imprint Code APO;GLP;5 Contains Packaging # Item Code Package Description Marketing Start Date Marketing End Date 1 NDC:70934-666-30 30 in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product 04/15/2020 06/30/2024 2 NDC:70934-666-90 90 in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product 12/21/2021 12/31/2024 3 NDC:70934-666-60 60 in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product 06/02/2022 12/31/2024 Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date ANDA ANDA075795 04/15/2020 12/31/2024 Labeler - Denton Pharma, Inc. dba Northwind Pharmaceuticals (080355546) Registrant - Denton Pharma, Inc. dba Northwind Pharmaceuticals (080355546) Establishment Name Address ID/FEI Business Operations Denton Pharma, Inc. dba Northwind Pharmaceuticals 080355546 repack(70934-666)


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1332.0.55.001 - CensusAtSchool Newsletter, Feb 2008
ARCHIVED ISSUE Released at 11:30 AM (CANBERRA TIME) 04/02/2008
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The CensusAtSchool newsletter is a service for users of the CensusAtSchool online learning project. It provides useful support information, project updates and community feedback on how the project is being used by teachers and students in schools across Australia. Each issue contains a feature article, a teacher suppport article and a general interest article, along with project updates, teacher tips and tricks and other related material. For more information on the CensusAtSchool project, visit https://www.abs.gov.au/websitedbs/cashome.nsf/Home/Home
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Holiday Classics Quilted Loop Earrings
Floral earrings to spruce up your outfit of the day. This pair adds an attractive and unique touch to any plain outfits.
Composition + Care
Most metal components are made with either 14k, 18k or 24k gold plated findings, 925 silver post, Japanese tensha beads imported from Japan/ semi precious stones/ glass/ premium silk tassels/ premium polymer clay.
925 silver post are suitable for sensitive ears. However sterling silver posts are naturally soft due to the high silver content and gets bent easily. Just straighten them back with a pair of pliers when it gets out of shape.
Avoid contact with harsh liquids. Gently wipe skin oils or sweat from jewelry after wear. Store in air-tight bag when not in use.
All handmade items are delicately handcrafted and are bound to have slight imperfections.
Dainty earrings measure within 15mm.
Standard earrings measures from 15-25mm
Statement earrings measures from 25-45mm
Clip Ons Options
For non piercings, you may request for a conversion to clip ons by adding a pair of clip ons (RM8 only) under the category "add ons". If you are purchasing multiple pairs, do leave me a remark on which pair to convert.
Trinket comes wrapped in gift boxes. For gifting purposes, kindly leave me a note on which item to be packed separately BEFORE you checkout. You may also request to leave a handwritten message along with the gift. Please refrain from direct messaging me your requests on social media as it is hard to keep track on your social media handle with the order made.
Disclaimer: Each pair is unique and no two pairs are the same. Do expect slight imperfections as every single part is handmade from scratch. Clay earrings are all hand sculpted freehand, do expect a 10-20% variation within the pieces.
Proudly Designed and Handmade in Malaysia


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To locate optometrists in Clinton Township, MI with a patient rating of 4 stars or higher, you can use our advanced search feature on our website. Start by searching for optometrists in your area. Once you have the list of specialists, you can filter the results by patient ratings. Select the option for 4 stars or more to view highly-rated specialists near you.
Yes, we have a list of optometrists in Clinton Township, MI who accept UnitedHealthCare insurance plans. To find them, simply search for optometrists in your area and use our insurance filter option. Select 'UnitedHealthCare' as your insurance provider, and the search results will display specialists who accept this insurance plan.
To find optometrists with immediate availability in Clinton Township, MI, you can use our platform's search and filter options. Start by searching for optometrists in your area. Once you have a list of optometrists, you can filter the results to view those with appointment slots available today, tomorrow, or within 2 weeks. This allows you to quickly locate a specialist who can accommodate your needs without delay, ensuring you receive timely healthcare services when you need them most.
Yes, many optometrists in Clinton Township, MI are currently offering telehealth services. Telehealth allows you to consult with a specialist from the comfort of your home using video calls or phone calls. To find optometrists offering telehealth in your area, simply search for optometrists in Clinton Township, MI on our platform. When viewing the search results, you can filter by telehealth as an option to see specialists who provide remote consultations. Providers who accept telehealth are also noted on our provider search results.
Finding healthcare providers who speak different languages can be essential for effective communication and quality care. To locate such providers, initiate a search for optometrists in Clinton Township, MI, then you can filter by providers who speak different languages other than english.
To make the most out of your optometrists appointment, consider the following tips: jot down your symptoms, concerns, and questions before the appointment, be open and honest about your medical history, and actively engage in discussions about treatment options and lifestyle changes. Don't hesitate to seek clarification on any aspects you don't fully understand.
Consulting a optometrists in your local area offers several benefits. You can enjoy convenient access to appointments and follow-up care. Additionally, local optometrists are often familiar with the prevalent health conditions and risk factors in the region, allowing for more personalized treatment plans. Regular follow-ups and monitoring are also easier to manage when your healthcare provider is nearby.
Optometrists near you often stay updated with the latest developments through continuous medical education, attending conferences, and participating in research. This commitment to staying informed benefits their patients by providing access to cutting-edge treatments and techniques. Feel free to ask your optometrists about recent advancements during your appointments.
Accessing state-specific healthcare programs and resources in Clinton Township, MI is typically facilitated through the official website of your state's Department of Health or a similar state agency. These websites often provide information on Medicaid, state-funded health insurance programs, and resources for specific health concerns. Additionally, you can contact your local healthcare providers or community health centers for guidance on accessing state-specific programs and resources.
There are several options for low-cost or free clinics for uninsured individuals. You can begin your search by visiting the website of your state's Department of Health or accessing resources like the National Association of Free and Charitable Clinics (NAFC). Additionally, community health centers, nonprofit organizations, and local hospitals may offer sliding-scale fee clinics or programs designed to provide healthcare services to uninsured or underinsured individuals.
Connecting with local healthcare advocacy groups and organizations in Clinton Township, MI is an excellent way to stay informed and get involved. You can start by searching online for advocacy groups related to your specific healthcare interests within Clinton Township, MI. Many of these organizations have websites or social media pages where you can find information on meetings, events, and ways to become a member or volunteer.


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Update at 10:12 a.m. ET. It's Official:
"It's time for a development professional to lead the world's largest development agency," President Obama just said as he announced he is nominating Dartmouth College President Jim Yong Kim to head the World Bank.
Our original post:
"President Barack Obama will nominate Dartmouth College President Jim Yong Kim to head the World Bank," The Associated Press reports, citing "senior administration officials" as its sources.
CBS News White House correspondent Mark Knoller is , as is Reuters.
The White House, meanwhile, just announced that the president will make a "personnel announcement" at 10 a.m. ET.
The AP adds that:
"It's a surprise choice for the World Bank's top job. A physician by training, the Korean-born Kim is a prominent figure in the global health world. Officials believe his broad international experience will help counter criticism from developing countries weary of the U.S. stranglehold on the World Bank's top post. Bank President Robert Zoellick announced his resignation in February."
According to Dartmouth's website, Kim has been president of the college since July 2009. It adds that "he is a co-founder of Partners in Health (PIH) and a former director of the Department of HIV/AIDS at the World Health Organization (WHO). ... Before assuming the Dartmouth presidency, President Kim held professorships at Harvard Medical School and the Harvard School of Public Health. He also served as chair of the Department of Global Health and Social Medicine at Harvard Medical School, chief of the Division of Global Health Equity at Brigham and Women's Hospital, and director of the François Xavier Bagnoud Center for Health and Human Rights at the Harvard School of Public Health."
Kim was born in Seoul in 1959, Dartmouth says. His curriculum vitae is here.
Copyright 2020 NPR. To see more, visit https://www.npr.org.


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Skift Take
Driving from LA to Fullerton will be a hassel, though great for Orange County residents. And beyond partying up on the train, not tons of extra benefits like a faster train, etc.
California to Las Vegas 'party train' signs deal with railroad, could hit tracks in 2013
As if a weekend in Las Vegas isn't wild enough for Southern Californians, a Nevada entrepreneur is about to add five more hours of party to either end.
After striking an agreement with Union Pacific Railroad last week, the Las Vegas Railway Express is one step closer to bringing to life the X Train, a luxurious "party train" complete with big screen TVs, recliners and two ultra lounges.
"The whole idea is when you get on a train, you feel like you're in Las Vegas," said Michael Barron, president and CEO of the $100 million venture that hopes to launch its maiden voyage on New Year's Eve 2013. "It's essentially a nightclub on wheels."
Tourists can't get from Southern California to Las Vegas by rail alone, and Barron's company isn't the first to try and fix that. The much-talked-about XpressWest project proposes a high-speed train connecting Sin City to the region from which it draws 25 percent of its tourists.
But it's a multi-billion-dollar proposal that would require setting new tracks, and it's often panned as a "train to nowhere" because the first phase would start in relatively obscure Victorville, about 100 miles outside of Los Angeles.
The X Train proposal calls for an Amtrak crew aboard a 576-passenger train that runs at standard speeds on traditional tracks.
It would start in Fullerton, Calif. — already home to an Amtrak station and part of Southern California's Metrolink commuter train network — and end in downtown Las Vegas.
A conditional agreement with Union Pacific, approved Nov. 16, will allow the company to use a rail line that's currently limited to freight trains and hasn't served passengers since Amtrak discontinued its Desert Wind service in 1997 due to low ridership.
Tickets for the adults-only train would cost $99 each way and include a meal and beverage, with plenty more alcohol available for purchase. To keep ticket prices low, the company would try to make money booking Las Vegas hotels and entertainment for passengers.
With initial plans for one trip a day on Thursday, Friday, Sunday, and Monday, Barron believes he can attract tourists weary of the weekend traffic gridlock and perhaps hung over from their weekend revelry.
"Sunday is horrific," Barron said of the Interstate 15 corridor that links Las Vegas and its neighbor. "So now you've been up for 40 hours gambling and you have to drive for seven hours — that's just horrible. But people do it in spite of that!"
John Lawson, who was in Las Vegas from Orange County for a few days over Thanksgiving, said he'd like the option of hopping on a train rather than braving bumper-to-bumper traffic on the way back.
"If you party really hard, it sucks driving back," said Lawson, 28.
Vegas visitor Christina Bojorquez, 25, said she'd have to weigh the cost of the train ride against other cheap options, including discounted flights and sharing the expense of driving to Vegas.
"For special occasions it would be good, but not all the time," she said.
Tom Skancke, a transportation consultant for the Las Vegas Convention and Visitors Authority, pointed to the proposed trains and other alternatives to personal cars as options that could entice a new generation of tourists. A new Greyhound Express nonstop bus route between L.A. and Las Vegas launched earlier this month.
"These modes of transportation do appeal to a younger, more eco-friendly traveler," Skancke said. "This generation is more interested in passenger rail, transit and high-speed rail than previous generations."
There's still work to be done on the X Train to get it running by late 2013. The sixteen cars the company has purchased need to be renovated, and a station needs to be completed in downtown Vegas.
"We're four years and $12 million into it. It's a lot of infrastructure building," Barron said. "This is a simple concept in discussion, but it's complicated to do."
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Food is a topic of much discussion these days. Umpteen channels on the television talk, discuss, present and even produce insane competitions;all on food. There are millions of blogs and websites all over the internet bursting with tantalizing food and bulging with information. There are hundreds of opinions churned out every day about what food is good and bad for you. There are umpteen lists about "Five Foods to Never Eat" and as many about "Five Foods to ace an interview". You would think "Five" would be an easy number to handle ? Naah.
All around me there seems to be a Food bubble. And I do hope earnestly that the bubble does not burst. I am enjoying it.
But as much as I love this gastronomical propaganda I must admit I am also highly confused. There is too much information which is hard to assimilate and even trust these days. There is too much of competition about making food faster, prettier, healthier, better and while one day that means oodles of butter, on the other none of it.There are studies being churned out faster than the dollar bill and when it comes to food it is hard to ignore them even in my standard lackadaisical mode. Why my family's health might be affected by the brand new study, that still smells of fresh ink and crisp paper hot from the printer. My child might grow up to be a psycho because she was deprived of Himalayan acai berry juice as a toddler.
Local or Organic, Paleo or Vegan, Chinese Study or American, South Beach or Calangute, your garndmother's or mine ? The questions are just too many. And honestly if you notice the core of each of these studies and sum them up it might just be what your Mother had been saying all along and you blindly ignored. Ahhh, what does she know after all. Now grandmothers might be more knowledgeable.
When I was a child growing up in India, food was not a media darling. Few recipes in the Sunday newspaper and a couple of half hearted food pictures in the Bengali magazine was all we had to be satisfied with. Glossy magazines like Femina did not talk about food. News Magazines like India Today stayed far away from recipes and if at all, talked about the dearth of food or the high price of it. "Eat it, all of what is in your plate. Food is precious and there are people who are doing without it" was my Mother's common refrain.Food was revered and recipes were all hand me down or shared with neighbors. My Ma would sometimes cut out of recipes from the Sunday papers and with years they would begin to look like fragile parchment.
Food was a mainstay of the middle class household though. Starting with the morning bazaar routine, getting fresh supplies of seasonal vegetables and fish every day, cooking 3 meals from scratch each day without fail was the norm. We discussed food with love and passion, as something to be cherished and thankful about. Each time my Thama lamented the milk that the milkman got, comparing it with the creamy, almost reddish hued warm milk from the cows in her parent's home in Munger, we collectively sighed. When my Baba said that nothing tasted as good as his grandmother's ghee parathas and mohonbhog we imagined days dripping with drops of grainy tassar silk ghee.
My Ma's cooking usually bordered on the healthy where it was never oily or too spicy for comfort. Yet it was flavorful, always had a vegetable, a fish and grains. The vegetables and fish changed along the season, the dishes varied from light to rich with the temperature. Meat was cooked once a week. I lived my entire childhood yearning for an omlette made with 6 whole eggs which she steadfastly denied spreading the quota over the entire week instead. She or none in her generation stopped to think if it was right to feed this or that. The everyday diet was naturally balanced.
All her life my mother's food style remained the same unlike mine which jumps from no-grain in one week to brown rice only in another and raw salad one day to junk food the next. While she lived with maybe three main kinds of grains, my pantry has branded as well as un-branded packs of brown rice, quinoa, daliya, couscous, semolina, flax seeds, wheat germ and other un-inventoried item which I amass because the recent study said so. Needless to say I forget about many of them.
I don't know whether her style was correct or whether it worked because the raw food products then were not maligned by harmful chemicals. I am not justifying anything, all I am saying is it was much more easier to think of food and plan a meal then. There were set choices.
Now,every week we run around three different grocery stores. For what purpose I do not know. Organic spinach and strawberries from Whole Foods, flax seed from Wegman's, Bitter Gourd and hot green Chiles from Patel Bhai. And then someone comes and says "Local is far better than Organic" and so I again run around, driving 35miles, getting Zucchini from the farm stand which said "Local Produce". In between I have spent an hour debating whether the more expensive wild caught salmon is less contaminated than the farm raised.Thankfully Organic Milk and Eggs is now mainstream and so we can get that anywhere but now they say Milk is not at all necessary for the diet anyway so there my precious 265 hours were wasted.
Finally when I am home, drained both physically and financially I decide I need some rest and order a processed cheese artisan pizza from Domino's, glug down a splenda infused coke and try to think of the most edible way to cook the couscous so that I can contribute more food to the world wide web.
Of all the "gyaan" that is out there I probably like Michael Pollan's Twelve Commandments best.
More Vegetables.
Less Meat.
Minimal processed food. Cook more.
Eat at the table. Though I don't follow them strictly, they make sense.
But here is where I stumble.
"Don't eat anything your grandmother wouldn't recognize as food".
Ideally eating what my Grandmother recognized would have been right because I guess that is what my body was suited for but then came globalization and messed it all up. I eat pasta and broccoli in abundance, and I am guessing she would too if she lived with me in the US. Also when I eat some of what she ate like this "Potol" I am actually committing a crime by not eating "local". I have no idea where my Patel Brothers get their potol from but I am sure it grows nowhere in my backyard.
Potol was a vegetable I was never fond of but summer heat brings back memories of patol and grandmothers. I however did not buy potol again, twice in one summer is enough I decided. This recipe of Doi Potol -- PointedGourd in a Yogurt sauce is a recipe sent by my Mother. I haven't cooked it yet but the recipe I see is pretty universal and might go well with even eggplants. So that is what I am going to do with this recipe next, cook it with eggplants. You can do the same or if you have access to plentiful potols you can make one more dish with the same boring veggie.
1. Potol - 6 pc
2. Onion - half
3. Yogurt/Curd - 1 cup
4. Green chilli-- 4/5
5. Cumin/Jeera powder - 2 tea spoon
6. Ginger - 1 table spoon
7. Turmeric Powder - 1 tea spoon
8. Chilli powder - half tea spoon
9. Sugar - 1 tea spoon
10. Salt- according to taste
11. Garam masala - 3 elaichi, 1/2 " dalchini, 4 cloves
12. Tejpata - 1
13. Rosun - 1 koya /1clove
Prothome potol take bhajar moto ga ( body ) ta cheche niye ektu haldi & salt lagye bheje nite hobe. Then potol ta tule rekhe in that oil, garam masala & tejpata phoron debe. Then ote onion & rosun debe and ginger paste & sugar diye bhjte hobe. Now 1 cup doi ( curd ) haldi, lanka & jeera powder diye bhalo kore phetiye nite hobe. Onion bhaja hole or modhye ei curd diye debe and gas sim kore bhalo kore nere niye ote potol guli diye nara chara kore salt debe. Tarpore jal ( water ) diye dhaka ( lid ) debe. Potol boil hole green chilli long size chire (cut ) ote diye namiye nebe.
Scrape skin of potol/parwal and toss in salt and little turmeric powder.
Heat Mustard Oil in a Kadhai.
Fry the patol lightly, remove and keep aside.
Temper the same oil with Whole Garam Masala and TejPatta.
Add the finely chopped onion and garlic and saute. Next goes in the ginger paste. fry with a tsp of sugar till onion is soft and browned.
Meanwhile in a bowl add the yogurt, Cumin Poder, Chili powder and littel turmeric powder. Beat well.
Once the onion is done, take the kadhai off the heat and slowly add the yogurt. At low heat cook add the fried potol and mix well with yogurt and masala.
Add water for gravy, add salt, cover and cook till the potol is done. Once the potol is done add the green chili and switch off heat.


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Gingerbread Authentic Libbey Glass Cup
- Low stock - 5 items left
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HAND WASH ONLY with lukewarm water. Do not soak or leave submerged in water for extended periods of time. Not recommended for use in the dishwasher or microwave.
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Drinkware is final-sale.
Turnaround time varies per product and is provided in the Announcement Banner at across the top of the site; processing times are updated periodically depending on volume of orders and demand.
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PRE-ORDER (or made-to-order) i.e. graphic tees: Standard turnaround time is between 1-2 weeks for processing/production (unless otherwise stated).
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9:00 - 14.6 miles / 29 minutter - 9:29
Pee Dee Valley Drive - end
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Registered Nurse - Med Surg
Company: Encompass Health Rehabilitation Hospital of Largo
Location: Largo
Posted on: July 9, 2024
Job Description:
Registered NurseA stronger bond with patients
A stronger impact on recovery
As a registered nurse (RN), you'll be the connection between
compassionate care and the real, positive results your patients are
striving to achieve. Use your skills within our inpatient
rehabilitation setting to provide the nursing perspective and
attention to detail that our highly specialized, integrated team
approach requires. Elevate expectations and outcomes with national
post-acute care leader Encompass Health.
What Makes Encompass Health Careers Different-and Better:
Working at Encompass Health means being part of something special:
A team that is passionate about making an impact on patients' lives
each day. Unlike the typical hospital setting, Encompass Health
offers you the unique opportunity to walk alongside patients on
their road to recovery from stroke, spinal cord injuries,
neurological disorders, joint replacements, multiple trauma and
cardiac/pulmonary conditions. As you help patients achieve goals
and regain independence, you can form significant relationships
with them and celebrate the successes they experience along the
Our culture of compassion and collaboration is founded on more than
just the care we provide our patients; it is expressed in the
values we live. We encourage and empower each employee to keep
learning and growing by providing the resources to deliver a better
way to care. At Encompass Health, you'll find something decidedly
different and more satisfying: A career that is challenging,
inspiring and rewarding. Maximize your talent and join a team that
is committed to setting the standard for better healthcare with
this engaging opportunity:
As a registered nurse at Encompass Health channel the full extent
of your knowledge, skills, ambition, and experience on a daily
basis. Inspire our patients to progress each day as you:
Help patients by supervising care and treatments, leading patient
assessments, creating personalized plans of care, targeting patient
concerns and offering the best solutions.
View each patient with a strong sense of empathy, listen closely to
their personal stories, and get to know each one's physical, mental
and emotional needs.
See patients progress due to the effort you and your team put forth
each day and build rewarding relationships with them during stays
that last from two to four weeks.
Spend each day helping someone to regain control of their lives
with the goal of being discharged from the hospital and back to
their community, families and friends.
Current RN licensures appropriate to state regulations
CPR certification required (ACLS preferred).
CRRN certification preferred.
One or more years of experience in an inpatient rehabilitation
hospital setting preferred.
Enjoy competitive compensation and benefits that start on day one,
Benefits that begin when you do.
Affordable medical, dental and vision plans provided to meet the
needs of full and part-time employees and their families.
Generous paid time off that increases with tenure.
Tuition reimbursement and continuing education opportunities.
Company-matching 401(k) and employee stock-purchase plans.
Flexible spending and health savings accounts.
About us:
Helping patients regain hope and independence, Encompass Health is
a national leader in post-acute care. We operate rehabilitation
hospitals and offer home health and hospice care in 36 states as
well as Puerto Rico. Following the Encompass Way, we are driven by
our core values: We proudly set the standard, lead with empathy, do
what's right, focus on the positive, and remain stronger
Realize the powerful difference you can make. Take this opportunity
to join our team.
To learn more about us, visit us online at encompasshealth.com
Connect with us:
Equal Opportunity Employer
Keywords: Encompass Health Rehabilitation Hospital of Largo, Largo , Registered Nurse - Med Surg, Healthcare , Largo, Florida
here to apply!


text:
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