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Nadi Astrology Nizampet Hyderabad
Nadi Jyothisham Nizampet, Nadi Astrologer Nizampet Hyderabad
We are providing spiritual and divine Nadi Astrology Online service to the people who are in the search of their Nadi Palm leaf to know their future life predictions and bring peace, Joy & happiness in their life.
We are one of the famous Nadi astrologers in Nizampet Hyderabad, Maharashtra, India, USA, England, Canada, Singapore, Australia, New Zealand, India, Dubai, Malaysia, Japan, Russia, Germany, UK, China & many more countries across the globe.
Our SRI ATRI MAHARISHI NADI ASTROLOGY CENTRE is located in India – Vaitheeswaran Koil, Tamilnadu. Our Chief Nadi Astrologer Dr.K. Selva Muthu Kumaran Ph.D., DHA is one of the famous & genuine Best Nadi Astrologer in Nizampet Hyderabad & Jeeva Nadi Astrologer in Nizampet Hyderabad, India. We have been providing Nadi Astrology online services, Atri Jeeva Nadi reading, Jeeva Nadi Jyothisham, Jeeva Nadi online services, Atri Jeeva Nadi Jyotish, Atri Nadi Astrology, Agastya Nadi Astrology, Atri Nadi Jyotish, Siva Nadi Astrology, Agastya Nadi Jyotish, Siva Nadi Jyotish, Nadi Shastra reading, Palm Leaf reading, Nadi reading online services, Nadi jyotish online predictions, Nadi Jyothisham online consulting to the customers from Nizampet Hyderabad, India for past three decades.
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We provide the best Nadi astrology predictions for people who believe in and come to us. After finding out their Nadi palm leaf we predict them about their future accurately and suggest certain remedies to clear their karmic debt as written in the ancient Nadi palm leaves detail and as accurate.
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Laws and Policies
Louisiana Administrative Code
Includes Notice of Intents and Rules promulgated by the Department of Revenue and published by the Office of State Register. Title 42 of the Louisiana Administrative Code (LAC) contains the rules for the Office of Charitable Gaming. Title 55 of the LAC contains the rules for the Office of Alcohol and Tobacco Control. Title 61 of the LAC contains the rules for taxes administered by the La Department of Revenue. Complete set of rules promulgated by the Louisiana Department of Revenue can be obtained through the Office of State Register.
Policy Documents
Contains Revenue Rulings, Redacted Private Letter Rulings, Statements of Acquiescence or Non-Acquiescence, and Revenue Information Bulletins issued by the Louisiana Department of Revenue since 2001.
Policy Statement Subscription Service
Be notified by e-mail whenever the Department posts a notice of intent, rule, revenue ruling, redacted private letter ruling, statement of acquiescence or revenue information bulletin on its website.
Louisiana Tax Institute
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subset: commoncrawl


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How to install CPAN modules
Here are some recommended approaches to installing modules from CPAN, as with much of Perl there are several alternatives.
Some basics
Most Perl modules are written in Perl, some use XS (they are written in C) so require a C compiler (it's easy to get this setup - don't panic), see your OS of choice below to find out how to get the right compiler. Modules may have dependencies on other modules (almost always on CPAN) and cannot be installed without them (or without a specific version of them). It is worth throughly reading the documentation for the options below. Many modules on CPAN require a somewhat recent version of Perl (version 5.8 or above).
Quick start
Install cpanm
to make installing other modules easier (you'll
thank us later). You need to type these commands into a Terminal emulator
Win32, Linux)
cpan App::cpanminus
Now install any module you can find.
cpanm Module::Name
To help you install and manage your modules:
local::lib enables you to install modules into a specified directory, without requiring root or administrator access. See the bootstrapping technique for how to get started. You can create a directory per user/project/company and deploy to other servers, by copying the directory (as long as you are on the same operating system and perl version).
cpanm from App::cpanminus is a script to get, unpack, build and install modules from CPAN. It's dependency free (can bootstrap itself) and requires zero configuration (install instructions). It automates the entire build process for the majority of modules on CPAN and works well with local::lib and perlbrew. Many experienced Perl developers use this as their tool of choice. Related tools: cpan-outdated, pm-uninstall, cpan-listchanges.
perlbrew from App::perlbrew is useful if your system perl is too old to support modern CPAN modules, or if it's troublesome in other capacities (RedHat/CentOS are included in this list). perlbrew makes the process of installing a Perl in any directory much easier, so that you can work completely independently of any system Perl without needing root or administrator privileges. You can use multiple versions of Perl (maybe as you upgrade) across different projects. The separation from your system Perl makes server maintenance much easier and you more confident about how your project is setup. Currently Windows is not supported.
cpan from CPAN has been distributed with Perl since 1997 (5.004). It has many more options than cpanm, it is also much more verbose.
cpanp from CPANPLUS had been distributed with Perl since 5.10 (2007) until 5.20 (2014). This offers even more options than cpanm or cpan and can be installed just like cpanminus.
Perl on Windows (Win32 and Win64)
Strawberry Perl is an open source binary distribution of Perl for the Windows operating system. It includes a compiler and pre-installed modules that offer the ability to install XS CPAN modules directly from CPAN. It also comes with lots of modules pre-installed, including cpanm.
ActiveState provide a binary distribution of Perl (for many platforms), as well as their own perl package manager (ppm). Some modules are not available as ppm's or have reported errors on the ppm build system, this does not mean they do not work. You can use the cpan script to build modules from CPAN against ActiveState Perl.
Perl on macOS
macOS comes with Perl pre-installed. in order to build and install your own modules you will need to install the "Command Line Tools for XCode" or Xcode package - details on our ports page. Once you have done this you can use all of the tools mentioned above.
Perl on other Unix like OSs
Install 'make' through your package manager. You can then use all of the tools mentioned above.
Other tools
CPAN::Mini can provide you with a minimal mirror of CPAN (just the latest version of all modules). This makes working offline easy.
CPAN::Mini::Inject allows you to add your own modules to your local CPAN::Mini mirror of CPAN. So you can install and deploy your own modules through the same tools you use for CPAN modules.
Which modules should I use?
Task::Kensho lists suggested best practice modules for a wide range of tasks. https://metacpan.org/ will let you search CPAN. You could also get involved with the community, ask on a mailing list or find your nearest Perl Mongers group.


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Round Solitaire Diamond Set in 18ct White Gold 0.40ct
✨ We keep some sizes in stock. If your size is not immediately available a member of our team will be in touch after completing checkout ✨
Free Ring Resizing
Lifetime Cleaning & Care
Signature Packaging
Tracked Insured Delivery
Buy Now, Pay Later
- Description
The Gear Jewellers Zora ring is a timeless solitaire. This design portrays a classic and elegant look.
The round brilliant diamond is generally considered, by diamond experts, to be a superior cut to a fancy diamond shape. It gives the proper reflection of light and maximises potential brightness. The castille setting following into the shoulders shows off each diamonds individual sparkle.
SHAPE Round
STYLE Solitaire
METAL 18ct White Gold
CARAT 0.40ct
ORIGIN Natural
Unsure of your ring size?
Get a complimentary ring sizer delivered to your addressA CLOSER LOOK
With a team of diamond advisors and gemmologists at your disposal, why not explore our diamonds and ring designs with help of an expert, dedicated to finding you the perfect ring.
Absolutely thrilled with the engagement ring I purchased! The team at Gears were so patient and knowledgeable, guiding me to the perfect choice. My partner is in love with it, and I couldn't be happier.- Liam & Sophia
Care for Your Ring
We are here to provide you with a lifetime of care for your beautiful diamond ring. If you ever need advice or just a check up to make sure your ring is in its best possible condition we are always here and happy to help in
Free Sizing Service
We offer a free sizing service. Our experts will measure your finger in store with great precision; once we have your size our goldsmith can adjust the ring accordingly.
Free Cleaning Service
Our ultra-sonic cleaner is always on and ready to clean your ring whenever you call into see us. Your diamonds will always sparkle as much as the day you got them, once they are kept clean. We want you to enjoy the beautiful sparkle of your ring for a lifetime. Come into us at least once a year (or as often as you like) to have your ring professionally cleaned. When we clean your ring we will check the setting to make sure everything is ok. If we feel a stone has become loose or you could benefit from a professional polish and plating we will advise you. You will have peace of mind that we have your best interests at heart.
Rhodium Plating and Polish
We can provide a professional rhodium plating and polishing service. Our skilled polisher removes any marks, scratches and scuffs that build up over time bringing it up to a highly polished finished. He will then electro-plate the precious white metal rhodium over your white gold or platinum mount that will give it the bright white shine that your ring had the day you bought it. We recommend that you avail of this service every two to three years.


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LOS ANGELES (thefutoncritic.com) -- The latest development news, culled from recent wire reports:
Looking to keep track of all the various projects in development? Click here to visit our signature "Devwatch" section. There visitors can view our listings by network, genre, studio and even development stage (ordered to pilot, cast-contingent, script, etc.). It's updated every day!
Sources: Variety, The Hollywood Reporter, Reuters


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Downtown on the Square
Most buyers choose to drive by your home first before wanting to set an appointment to view. An attractive yard that is free of debris will gain interest quickly. Make sure that trees are trimmed and that your home can be seen from the street. Have the grass mowed, trimmed and edged. Walkways should be swept. Clean away all debris. Remove parked cars or RVs. When in season plant flowers to add color.
Remember, if the buyer does not like the outside, that person simply drives on to the next house. Get your home ready for drive by traffic and give folks something extra nice to look at.
Call us today for a no-nonsense, no obligation assessment of your homes value and let me show you the key factors in obtaining a top dollar sale on your home! We would definitely like to help you in any way we can!


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Gloss MkII Vessel Mixer (Multiple Finish Options)
More ways to pay
- Cold Start cartridge (centre lever position) for energy saving
- 25mm ceramic cartridge with 15 year warranty
- Extended body height for use with above-counter basins
- Durable, high-quality finish
- Designed in Australia
- Matching accessories to complete the look
- WELS Registration Number: T41520
- WELS RATING: 6 star - 4.5lt/min
- PRESSURE RATING :150 - 500kPa
- 15 Year Cartridge Warranty
- 7 Year Product or Parts Warranty
- 7 Year Finish Warranty
- 1 Year Labour Warranty
We guarantee that we bring you the lowest prices possible every day, and that's a promise. However, if you happen to find a cheaper advertised price on an identical stocked item that's in stock with our competitor we will not match it.
When price matching online stores we also take into account the added cost of delivery. If the identical product can be purchased and delivered via an online store for a total price lower than the one we are offering, we will match that total.
What items does the price match guarantee apply to?
All identical products with identical terms and conditions that are stocked at Online Bathroomware and in stock at our competitor.
What items are excluded?
- Non identical products and services (inclusive of non identical warranties)
- Cash back and coupon offers
- Resellers
- Customer special order
- Contract Pricing
- Competitor clearance products
Online Bathroomware reserves the right to limit the quantity of products available for price-matching at its discretion. The Price Guarantee does not extend to resellers.
Best prices around. Absolutely stellar customer service. I would definitely order from them again. Thank-you for all your help with my order. I'll be dealing with you again soon.
~ Angela K.
Fancy $50 Off Your First Order?
We'd love to help you with that. Enter your email address for your unique code. *Orders above $400


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7 sold in last 62 hours
save 25%
Payment methods
Stretched VS Unstretched (Rolled in a tube)
Please, pay attention that this information doesn't apply to prints and products made of wood and metal.
Unstretched (Rolled in a tube) painting will arrive rolled in a dent-resistant tube without any stretcher bars on its back to support it.
Stretched painting
comes with wood stretcher bars that have been attached against the back of the painting (ready to hang).
Framed painting arrives stretched on wooden bars and framed in one of the listed floating frames.
Canvas stretcher depth is 0.87"/2.2 cm.
Producing & Delivery
This abstract painting will adorn and transform any modern interior!
Our paints:
- Free professional shipping worldwide
- 100% handmade oil & acrylic painting
- Truly rich texture and vivid colors
- Safe, non-toxic and durable paints on cotton canvas
- Any size of artwork up to 114"x114"/ 290x290 cm
- Floating frame is an extra option. You get an artwork ready to hang
- Easy money back within 14 days
We show you the photos or video of the painting for your confirmation before the shipment. We always make all necessary changes if you wish.
Due to the color distortion by the monitor, camera settings and other factors, the color of the product in the photo may vary from its actual color.
Please feel free to contact us at email@example.com anytime!
Please, pay attention that this information doesn't apply to prints and products made of wood and metal.
Production time usually takes 1-2 weeks, if you have any exact deadlines, please kindly let us know about them, so we can do our best to met them!
Delivery will take about 5-7 days from the moment of shipment.
- Custom orders: we accept custom orders. Please send us a request so we can discuss if we can make it happen. Once we complete the artwork, we will send you photos for your approval. You can request any changes or color adjustments if needed;
- In-stock paintings: will be shipped out in 1 business day and delivered in 1 week after dispatch.
We offer free worldwide shipping with our artworks!
Need more information?


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Let's celebrate those eight crazy nights with some kugel!
My friend Jami has a lovely mom who can cook. Oh vey! She's the best! Her brisket is out of this world, mandel bread, Matzah brei, and Matzo ball soup...so yum! She's definitely my adopted Jewish mom.
Although most celebrate Hanukkah with latkes (potato pancakes), those are best eaten straight out of the hot oil. I decided to make kugel so I could bring it into work!
Note: I baked the kugel last night and these photos are of a cold kugel. The warm kugel will have a different consistency. I like it hot, warm, cool and cold! :) You can make kugel sweet or savory and add all sorts of goodies such as pineapple, raisins and even more dairy products. However, I love Mrs. S recipe and can't imagine it any other way!
"Mrs. S" Special Noodle Kugel Recipe
8 oz. medium noodles
6 eggs
1 lb. (16 oz.) carton cottage cheese, small curd
3 oz. small cream cheese [FYI: A regular brick is 8 oz.]
1/2 pint = 1 cup = 8 oz. container sour cream
1/4 lb. = 1 stick butter, melted
3/4 cup sugar
1 tsp. vanilla
Handful of cornflake crumbs to thicken the noodle-egg mixture a bit
Cook and drain noodles. Beat eggs well, add rest of the ingredients and beat well. By hand, mix in the drained noodles.
Mix together:
1 cup corn flake crumbs
1/2 stick butter, melted
1/2 cup brown sugar
1 tsp. cinnamon
Grease a 9 x 13 pan well and add mixture. Sprinkle topping on. Bake 1 1/2 hours at 350 degrees, uncovered.
Happy Anniversary Cyndi and Perry!


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Personalized Highway Distance Sign To: Amway Center, Home of the Orlando Magic
Each sign is individually personalized with the total driving distance to the Amway Center (400 W. Church St. #200, Orlando, FL 32801). ----------------------------------------------------------------------------------------------
Note: TravelSigns, Inc. is not affiliated with or endorsed by any third party whose company name or location may appear on this website or any TravelSigns, Inc. product. None of the distance signs advertised by or made by TravelSigns, Inc. are "official" university or team memorabilia; and TravelSigns, Inc. produces its distance signs for informational purposes only.
Product Options:
This sign is available in three product options:
7" x 5" Aluminum w/magnets
12" x 8" Aluminum with 1/4" mounting holes
18" x 12" Aluminum with 1/4" mounting holes
Here is how the customization process works!:
1. Type in the address for distance calculation. It can be a full mailing address, a city, or zip code.
2. Select whether you want miles calculated to be point-to-point or driving distance.
3. The calculated miles will appear in the "miles" box below! Congratulations - you have now officially calculated the desired miles for your distance sign!
4. Head to check out now to buy your new distance sign!
* You may also simply type in the desired number of miles in the "calculated miles" box if you wish to skip the distance calculation! *
----------------------------------------------------------------------------------------------Printed on .032" Heavy Gauge Aluminum with a high gloss finish; our replica U.S. Highway signs are designed using DOT specified fonts and colors; capturing the look and feel of an actual highway distance sign.
Your ultra-durable Travelsign can be displayed anywhere!:
Home Bars
Man Caves
or anywhere you support your favorite team!
Travelsigns are:
Lightweight, easy to hang
Rugged and low maintenance, easily cleaned with a damp cloth
Directly printed (no decals) on UV Resistant Materials
Have an idea for another custom distance sign? Please contact us and let us know!
100% Satisfaction Guarantee!
Materials: Aluminum Sign Blanks,UV Resistant Inks,High Gloss Finish


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Sending well wishes to your friend or family member staying with us at Greenwood Village is now easier than ever. Your kind thoughts, prayers, and words of encouragement can be helpful to the healing process. Simply fill out the form below with a personal message and pick a design to accompany it. Our team will hand deliver your card to your loved one's room.
- Select an image by clicking it
- Fill out the form and write a personalized message at the bottom of the page
- Click "Send" and the ecard will be printed and delivered by one of our staff
- Deliveries are made Monday through Friday
- Cards are typically delivered the next business day but may take extra time around holidays
- If the patient has been discharged your card will not be delivered


text: Get Fit (No Ratings Yet)Loading... Arcade admin 11 Sep , 2020 0 PLAY NOW! GAME INFO Are you well-padded and want to lose a few pounds? Get Fit turns working out and getting in shape into fun and entertaining mini games. In each of the mini games you accompany a character on it's way from being chubby to a real beefcake. You can test your reaction in sports like rope skipping, lifting and the famous hula hoop. The longer you play the fitter your character gets. Just like in real life getting fit is easier as staying fit. If you start to slack off and skip your training for some days your character will gain weight again. So make sure to come back every day and work out! Play Get Fit now for free!


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Robert Langer is sort of a modern-day Thomas Edison. He holds over 800 patents. He's launched two dozen startups making an eclectic variety of stuff from tumor-zapping nanoparticles to biosensors and blood tests, synthetic spinal cords, even anti-frizz hair products, all of this originating from the same lab. And recently, President Obama awarded him the National Medal of Technology and Innovation. He's already won the National Medal of Science, after all.
How does he do it? How are these great ideas born? And how do you create a place, like the Langer Lab, where innovation and creative thinking can thrive? Well, let's ask him. Robert Langer is an institute professor in the Departments of Chemical Engineering, Bioengineering, Mechanical Engineering at MIT in Cambridge. He joins us today from a studio on the campus. Welcome to SCIENCE FRIDAY, Dr. Langer.
ROBERT LANGER: Thank you very much.
FLATOW: Did you start work in a garage like David Packard, Steve Jobs, people like that?
LANGER: No, I didn't. I started doing some research at Cornell University when I was an undergrad student, and then MIT as a graduate student, and then Boston Children's Hospital and Harvard Med as a post doc.
FLATOW: And how did you move on from there?
LANGER: Well, after being at Children's Hospital, I went back to MIT, and...
FLATOW: Yeah.
LANGER: ...I've been there ever since.
FLATOW: What do you think that some great inventors of our time - I'll include you and Elon Musk and Dean Kamen and people like that - what do you have in common?
LANGER: Well, I don't know. Those are some pretty great inventors. I think probably, though, people like that have a tremendous amount of persistence. They probably, also, aren't necessarily bound by what I guess I'd call conventional wisdom, which is how you're sort of supposed to think. I suppose those would be some of the characteristics.
FLATOW: Mm hmm. So does it take some sort of stick-to-itiveness? In other words, you don't care what people think that you're doing. You're self-confident in your methods and techniques and where - and what you have in mind.
LANGER: I don't know that they're necessarily self-confident. I don't know that I'm so self-confident, and I'm not sure about the other people you mentioned, but I think it does take stick-to-itiveness. I mean, you know, I think in science you fail much more often than you succeed, and you just have to be persistent and never give up. And then also a lot of times, people will tell you that your ideas aren't going to work and things like that, and so you have to just keep hanging in there.
FLATOW: Do you ever make anything, and then you think, this is a great idea, but what the heck do I do with it?
LANGER: Oh, all the time. In fact, we just published a paper in science about a month ago where we came up with some new materials that when a little bit of moisture goes in, it starts moving all over the place, and it can generate a lot of energy and things like that. And - but we're really not sure what the, you know, we're really not sure what the best application is for something like that.
FLATOW: And so do you then give it away? Or certainly, if it's valuable, you're not going to let people, you know, take it for nothing.
LANGER: Well, I think it depends on what you're doing. I mean, in our case, I mean, we certainly do write patents, but we publish everything we do. So anybody's welcome to try to use it and come up with, hopefully, good uses for it. So everything we do like in an academic institution is - you know, goes to the public in that sense. But sometimes, what you also want to do is - because it's hard to, particularly in medicine, to get enough funding to do the work as you do want to have patent so that people, investors are willing to support you so that you can take things, for example, into the clinical trials and things like that.
FLATOW: Talking with Robert Langer. Our number is 1-800-989-8255. If you want to get in on our conversation, you can also tweet us, @SCIFRI, at S-C-I-F-R-I. And talking about invention, engineering, whatever, with Robert Langer trying to pick his brain. What are you most proud of, Dr. Langer?
LANGER: Well, I'm probably most proud of my students. I mean, I've had about 500 students and post-docs and about half of them have gone on to terrific faculty positions. Many people are - many of them are deans of different colleges and - deans of engineering or deans of medicine. A lot of them are department chairs, many hold endowed chairs. I think I have 11 of them are members of the National Academy of Engineering. And another half, probably another 250 or so have gone on to help start companies or had a high positions of companies and have created all kinds of new technologies and inventions for the world.
FLATOW: All right. We're going to come back and talk about some of those inventions and engineering with Robert Langer right after this break. Stay with us. I'm Ira Flatow. This is SCIENCE FRIDAY from NPR.
FLATOW: You're listening to SCIENCE FRIDAY. I'm Ira Flatow. We're talking, this hour, about science innovation, invention engineering with Robert Langer, Institute professor at the Department of Chemical Engineering, bioengineering, mechanical engineering at MIT. Our number 1800-898-8255. Looking at all those different departments at MIT, do they contribute to each other when you get an idea? Can you crowd source it to each other, do they get it on the top view? Do you all seek thank kind of inclusion of everybody?
LANGER: Well, what happens is this, have students from all those all departments in our lab and actually other departments too. And in addition, I end up collaborating with different faculty in those departments. And also, I should say, some of my former students, they're all faculty in those three departments as well.
FLATOW: Uh-huh. But do you think that's needed? That kind of cross-fertilization of ideas?
LANGER: Yeah, I think. Well, for what we do, I think it's very, very helpful. I think that when you, you know, we're combining biology with engineering. And so I think having that kind of cross-fertilization of ideas is - and skill sets is very, very helpful if you're trying to create kinds of new materials for medicine and things like that.
FLATOW: Let's go to the phones. Terry in Brewster Town, Tennessee. Hi, Terry.
TERRY: Thank you, Ira and Dr. Langdon(ph). Dr. Langdon, how do you avoid the buying up and shelving of the technology or the good ideas by major corporations like has been changed with the patent laws recently?
LANGER: Yeah. Well, we patent our - I mean, we patent - MIT is pretty good at patenting things. Since we have quite a few patents as was mentioned, I think, in my introduction. So we do that, and a lot of times, what we've also done is to create small start-up companies with our students and to develop the technologies to, you know, to a large degree. So there are probably something like over 50 products, at least, that have come out from our lab that are actually now, being used during various stages of clinical trials.
FLATOW: We've heard so much about the U.S. falling behind in science and engineering, why think are so successful if we're so far behind?
LANGER: Well, I think, you know, what's happened, I think, is there's always got to be a frame of reference- the U.S. is still, I think, done well at MIT - I'd like to think, is doing well. But I feel I've been very fortunate in terms of having had great students and great collaborators my whole life and I think having, you know, when you work with related people, it's not that hard to be successful.
FLATOW: Well, do you think that's overblown that idea that we're - we don't produce enough qualified science and engineering students, do we?
LANGER: I think that - I think the concern is that we're slipping, and I think that that's true. I think that unfortunately, at the grammar school and high school level, I think that science education, and certainly engineering education, is not what it could be. And I think there have been various reports from like, the National Research Council a few years ago, like Rising Above The Gathering Storm had point out that the United States is, I think, sliding in significantly in these areas. So I think the concern is warranted.
FLATOW: But you will admit, and you have heard this from other researchers and engineers, that even though we may be slipping, there is something unique about American innovation, Yankee ingenuity of new ideas. Would you agree with that?
LANGER: I do agree with that. I think that it's - I think what happens is you have a tremendous entrepreneurial spirit in the United States. I mean, obviously, that's somewhat self-serving and I'm prejudiced. But I do think that the entrepreneurial spirit in the United States is terrific. People are willing to take risks. They are willing, sometimes, to go against conventional wisdom, and I also think the colleges in the United States are, you know, there was a lot of excellent colleges and universities. So I think that's - that that's right.
FLATOW: And why is that? Is there something about our culture or what?
LANGER: That's a very good question. You know, maybe it's in our genes and - but I think, you know, that that goes - some of it goes back to how America got founded in the first place, people were willing to take risks and I think people are continuing to be willing to take risks.
FLATOW: Can we get any ideas from outside of science? You know, stimulate you. Maybe from the arts, something you see in the theater, something you watch on Netflix?
LANGER: Oh, sure. All - yeah, all kinds of things. I mean, I've had ideas, for example, you know, one time I was watching a television show on PBS about how they made, for example, certain types of microchips in the computer industry and I thought about ways that we could kind of do - create a different kind of chip that might be able to deliver chemicals and - by remote control. And we actually did that with John Santini, one of our students, and Mike Cima, another professor at MIT. And now there's a company actually doing that and they're even in human clinical trials where you could do remote-control drug delivery.
And I've gotten other ideas. I remember one time I was reading Life magazine, and they were talking about cars of the future and how someday you could have a car that if it got in an accident, you'd just heat it up and it would snap back into shape. And so it occurred to me that we could make all kinds of materials that we could change their shapes by temperature or light or things like that. So, yeah, lots of time you can get different ideas from different sources.
FLATOW: What's that wire that when you heat it, it goes back? I can't think of the name of it. I'm having a senior moment.
LANGER: You mean Nitinol?
FLATOW: Nitinol, yes. Thank you very much.
LANGER: Sure.
FLATOW: I remember when that came out.
LANGER: Good memory.
LANGER: Now that you've thought of it.
FLATOW: I have to credit Charles Bergquist, my director, yelling it in my ear, so it's not me.
LANGER: I see.
FLATOW: Let's talk about other interesting things. Like how did you come up with this anti-frizz hair product? You weren't looking for that specifically, were you?
LANGER: No. Well, here, what happened is, you know, I - one of the venture groups that I've done a lot of work with is Polaris Ventures, and Jon Flint, who is a senior partner there and Amir Nashat, who is one of my former graduate students and now a general partner there, they were interested, you know, we've started - they've help to start a lot of medical companies. And one day they came to me and they were interested in starting a hair company. And so they said, well - one of the things they were interested in from talking with some of the hair people, hair stylists like Miss Di Rosa(ph) was could you come up with materials that would prevent frizz?
So we looked at this. And Dan Anderson and - who is one of my colleagues and myself, as well as others at the company, and we realized that pretty much every company in the world that makes an anti-frizz product uses exactly the same ingredient, silicone. And actually, that happens in medicine too. People sometimes use exactly the same thing, just some off-the-shelf thing. So we took a much more fundamental look at it and thought that we could come up with materials that would work better because they could keep water out better and also be much lighter on the hair. And so that's basically how we in the company came up with it, and it does quite well.
FLATOW: Mm-hmm. You must me intimately involved with nanoparticles, nano technology.
LANGER: Well, that's something we've worked on for many, many years, yes.
FLATOW: Do you ever wonder about where all these particles are going and winding up in nature?
LANGER: Well, we look at where they go in the human body, and I think we have a pretty good idea of that. Of course, our goal is - and a lot of what we do is to put anti-cancer drugs in them that - well, there's different goals, but that's one of the goals, is to put anti-cancer drugs in them and send them, you know, right to the tumor and hopefully no other place. But you can only do that to a certain degree.
But we've actually been doing that. And there's another little company, Bind Biosciences, that Omid Farokhzad, one of my former fellows who's now a professor at Harvard Med School and I help start, and you know, so they're actually treating patients with cancer right now in clinical trials.
FLATOW: What is the most underfunded, under-researched area of science and engineering or technology that could really use a boost?
LANGER: Well, I think all areas are underfunded, and I think they all need a boost, especially they need a boost, you know, starting today or tomorrow. So I think it's, you know, science is just such an important thing. It drives what we - what the whole country does technologically and the whole world. So I - and I don't know that you can cite a specific area. I mean some people might like to. But the fact is, is sometimes it's the areas that we don't even realize right now what discoveries are going to be made.
So you want to be able to have enough funding so that if somebody comes up with an out-of-the-box idea, that might change the world for which there's no real category that it can get funded. And that's going to get harder and harder.
FLATOW: Let's go to the phones: 1-800-989-8255. Let's go to Leo in Long Island. Hi, Leo. Leo, are you there?
LEO: Hello?
FLATOW: Yes. Go ahead.
LEO: How are you?
FLATOW: Fine. Go ahead.
LEO: I just had a question. I just wanted to know what do you guys think about the energy situation that we're in in regards to primary fuel and (unintelligible) gasoline, and where do you see this in the next five to 10 years?
FLATOW: Hmm. Good question.
LANGER: Well, I don't know that I'm any expert on the energy situation. I mean, obviously, it's an area that needs a great deal of research. MIT is very active in that area, and I hope that with some of the work that's going on at MIT by others here, not myself, but others who are very active in it, that - and there's other places around the country too that are doing very good work that, you know, that real progress is made. That's another area where funding is going to be very important.
FLATOW: Let's go to Sean(ph) in Derba(ph), Wisconsin. Hi, Sean.
SEAN: Hello.
FLATOW: Hi there.
SEAN: My question is mainly about nanites(ph), nanobots. And how far have they come along in recent years. And would they ever be able to like - like we're starting to understand about DNA, and we're starting to implant, like, computer chips into the body to be able to do things. And I'm wondering if, like, we'd ever be able to combine the three and be able to actually have a baby created with like prosthetics or something like that.
FLATOW: Mm-hmm. OK. Thanks for calling.
LANGER: Yeah, well, I think a lot depends how you define nanobots, but I think there are tremendous advances. And you know, we are working in some of those areas. We're working on all kinds of nanoparticles, nanoparticles that could target to different parts of the body and nanoparticles that could be used for more rapid diagnostics. And as I mentioned, we're also working on new kinds of microchips that you could implant and actually regulate them by remote control.
And I do think the opportunity to combine these things are there, though right now they all, you know, have a lot of technological hurdles on their own, so you want to solve the easier problems first, which is to do them individual and get them to the point where they're really helping people. And then maybe once you get there, they certainly could be combined.
FLATOW: Mm-hmm. And how would you control where it goes?
LANGER: Well, what we've done is - with nanoparticles what we've done is put certain type of arrowhead on them and those arrowheads could be designed, depending on, let's say the cell's receptors that you're trying to go to. So there are certain receptors, for example, on some types of tumors and there are certain receptors on some types of blood vessels, for example. And so by having the right arrowhead that will go, take the nanoparticles to the right places, you can, you know, get more of it there.
FLATOW: I'm Ira Flatow. This is SCIENCE FRIDAY from NPR, talking with Robert Langer. Our number, 1-800-989-8255. Let's go to Michael in Charleston, South Carolina. Hi, Michael.
MICHAEL: Hey, I enjoy your show. I have a 15-year-old daughter. She's into science and engineering and expresses her desire to go MIT one day. And wonder what courses she'll be taking. Are there any books that she could reading - she's in ninth grade - that would interest here and pique her interest to science more?
LANGER: Well, I think there's - well, first of all, in terms of what's good to do for a high school student, I think really the most important thing is just to learn the fundamentals, you know, learn really good chemistry and biology and physics and engineering if they have it. I think that's the most important thing. In terms - and if there's ever an opportunity to do research, for example, at the University of South Carolina or something like that, that would be also - or you know, also great. And Clemson. There's a lot of places that do good research there.
In terms of books, I mean I don't know. One of the things that sometimes always excites me are reading books about how people invented things and sometimes the struggles they have had. I remember the - there's one book called "The Last Lone Inventor," which is about the history of television and sort of the struggles that the guy who really invented television went through and, you know, sort of the process that he went through. And, by the way, when he did this, he was a high school student.
FLATOW: That's a kid. I'm trying to think his name.
LANGER: Philo Farnsworth.
FLATOW: Philo Farnsworth. How about a book about Nikola Tesla? Want to read about struggles.
LANGER: That would probably be interesting too.
FLATOW: Yeah.
LANGER: But all these stories are good because they show what people come up against and yet even though they came up against these things, they, you know, they made great inventions and made the world very different. Hopefully made it a much better place.
FLATOW: Let's go to Nick in Grand Rapids, Michigan. Hi, Nick. Welcome to SCIENCE FRIDAY.
NICK: Hi. Thank you. My question was, I'm a math and physics teacher, and I'm wondering about how to inspire students to further their studies in math and science. And then I also delve in a little bit of project-based learning, wondering how do we get students to reach out to experts like you to get advice with the work they're doing in the classroom?
LANGER: Well, I think there's different things that you can do. I mean first, I think one of the things that I think is important is to make things like math and physics fun. And, you know, and sometimes that can be done by different kinds of games and things like that. I think if somebody, you know, and then there's various things that they can avail themselves of. You know, like there are conferences, for example, like the engineering - they're having what's called Global Grand Challenges. There's actually a conference in England next month and - but they've also - there's websites that the National Academy of Engineering has on this, and that may also be helpful for people to look at.
And when you look at these websites, they'll list people, like myself and others who are involved in these things, and really, I get letters from high school people all the time and I do my best to try to answer them, and I'm sure the others would too.
FLATOW: Did you have a mentor or a teacher who helped you out?
LANGER: Well, in high school I had a couple people who were helpful, Danny Canales(ph) and Glenda DeLong(ph). But as post-doc, that I had - there was a clinician who I worked with named Judah Folkman. And he was really a real inspiration to me. And I think working in his lab had a major impact on my life.
FLATOW: Pretty famous name. Judah Folkman.
LANGER: Yes. Well, he was a great man.
FLATOW: Yeah. And any last words you have for investors who are, you know, trying to get along?
LANGER: Well, always, I guess, what I say is that I think that a lot of times you'll come up with an idea or an invention. And a lot of people tell you that it won't work, that it's impossible. And I think that's very rarely true. I think if you really believe in yourself, if you work hard, you keep being persistent, that you'll end up doing pretty well in those inventions.
FLATOW: You should know, you got 800 patents and two giant medals. Thank you, Robert Langer, for taking time to be with us today. Good luck to you. We'll be watching.
LANGER: Thank you very much.
FLATOW: Robert Langer is institute professor in the departments of chemical engineering, bioengineering, mechanical engineering at Massachusetts Institute of Technology in Cambridge.
Before we go, we just want to remind you about our photo contest. Yes, the entries are all in for our Winter Nature Photo Contest. More than 400 of you submitted your best shot. Now we need you to help pick the finalists out of 400. Yeah, go to sciencefriday.com/photocontest. Vote, vote, vote. You can vote many times. The rules are up there about how many times. Vote for your favorite and click on the cardinal, the nice red bird right there in the website, for more information.
That's about all the time we have today. If you miss us, go to our website, it's sciencefriday.com. Subscribe to our podcast and video, audio and video, iTunes is up there, Android apps, listen on our website at sciencefriday.com. You can also join our mailing list and our Video Pick of the Week is up there. It's nerd rapping. You'll love it. You can listen to some interesting new stuff. Have a great weekend. We'll see you next week. I'm Ira Flatow in New York. Transcript provided by NPR, Copyright NPR.


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Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome (IBS) affects the large intestine (colon) and can cause bloating, abdominal cramping and a change in bowel habits. Some patients with IBS have constipation while others have diarrhea. Some people go back and forth between the two. Although IBS is uncomfortable, it does not harm the colon.
IBS is common and more frequently affects women than men. No one knows the exact cause of IBS, but most people can control symptoms with a change in diet, medicine and stress management.
Symptoms of IBS
- Pain or cramping in the abdominal area
- Diarrhea
- Constipation
- Mucus in the stool
- Flatulence
- Uncomfortable bloating
Risk Factors of IBS
- Being female—more women are diagnosed with IBS than men.
- Family history—People with a close relative, such as a parent or brother or sister, with IBS are at higher risk for IBS. It is unclear as to whether the risk results more from shared genetics or a common environment.
- Being under 35 years of age—At least half of all people who are diagnosed with IBS are under 35 years of age.
Even though IBS is not harmful, it can be confused with other conditions. IBS symptoms may be similar to other diseases such as Crohn's disease, ulcerative colitis or even colon cancer. It is imperative that you see a doctor if you have significant changes in your bowel habits because IBS symptoms could be an indication of a more serious problem.
Tests to Diagnose IBS
There are no physical signs to diagnose IBS, so diagnosis usually occurs by a process of elimination. To be diagnosed with IBS, the most important symptom is abdominal pain that lasts at least 12 weeks (not necessarily consecutive). Other criteria include mucus in the stool, bloating, bowel straining and urgency and changes in the stool.
If a diagnosis of IBS seems fairly certain, a doctor may recommend treatment without any testing. If there are any reasons for concern, however, a doctor may recommend one or more of the following procedures.
- Colonoscopy- A test that examines the lining of the entire colon to check for polyps, inflammation and abnormalities.
- Flexible sigmoidoscopy- A procedure that uses a flexible tube to examine the the lower part of the colon.
- Computerized tomography (CT) scan- this test will show a cross-section of the internal organs and help diagnose other issues.
- Lactose intolerance tests- if lactase is not present in the body to break down milk sugar, you may exhibit some of the same symptoms as IBS such as cramping, bloating, constipation or diarrhea. This test can help differentiate between lactose intolerance and IBS.
- Blood test- Celiac disease, an allergic reaction to gluten, can have similar symptoms to IBS. A blood test can help exclude celiac disease.
Treatment for IBS
There is no cure for IBS, so the goal is to manage the symptoms.
- Controlling the diet—some people discover that certain foods will trigger IBS symptoms. Common triggers include alcohol, chocolate, carbonated beverages, certain fruits or vegetables or milk. Keeping a food journal and recording foods that cause constipation or diarrhea can be helpful.
- Stress management—like many other diseases and conditions, stress can make IBS worse. Planning ahead, making lists, meditating, taking time to relax and avoiding stressful situations can prevent aggravation of symptoms.
- Fiber supplements—Taking fiber supplements can help control constipation.
- Anti-diarrheal medications
- Anticholinergic medications—these drugs can help control painful intestinal spasms.
Medication for IBS
- Alosetron (Lotronex)—this medication was approved by the FDA, removed from the market, and now is approved again with restrictions. Alosetron helps relax the colon and slow down the bowels. It is only used when diarrhea is the prominent symptoms, and usually used when all other treatments have failed.
- Lubiprostone (Amitiza)—this drug increases fluids in the small intestine to help move the stool. It is generally only prescribed for patients with severe constipation when other treatments have been ineffective.


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NEW YORK (AP)-- TV viewing could soon sound a little calmer. The CALM Act, which limits the volume of TV commercials, goes into effect on Thursday.
CALM stands for Commercial Advertisement Loudness Mitigation. The act is designed to prevent TV commercials from blaring at louder volumes than the program content they accompany. The rules govern broadcasters as well as cable and satellite operators.
The rules are meant to protect viewers from excessively loud commercials.
The Federal Communications Commission adopted the rules a year ago, but gave the industry a one-year grace period to adopt them.
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CROATIA 5 lipa 2014 / Error: Extra metal on S and K / VF
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As with many fields, when it comes to trade, trust is the paramount quality in the world of collectibles.
As consumers, we give our trust to others on a daily basis: our doctor, lawyer, dentist, mechanic, even our hairdresser, are people with full access to fulfilling our specific wants and needs. Developing trust bonds is therefore a part of any successful contemporary existence.
It is the same with us: we cherish your trust, believing that the excellent service we render will bring you back to us anytime you choose to further on your collection, as well as the times you can use a non-biased and reliable advice.


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Kidzamo Fingerless Gloves, Red Flames
- Stretch lycra
- Gel padded palms
- Gloves are labeled medium for kids - Similar to XS in adult sizing.
- Size: Youth
- Gender: Unisex
- Color: Flames
- Glove Type: Fingerless
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The Best Tempered Glass Screen Protector for your Apple iPhone SE (2020 Model) with a Lifetime Warranty! Free Shipping anywhere within the United States!
Say no to cracks, keep your devices looking brand spanking new!
Included with purchase
1 x Red Zombie Premium Tempered Glass Screen Protector
1 x Micro fiber cleaning cloths
1 x Alcohol wipe
1 x Installation instructions
1 x Red Zombie Sticker
Easy Installation
A special adhesive makes the application and removal process easy.
Safety Tempered glass minimizes injury if the glass is broken.
Note: The edges of tempered glass products may chip if they come into contact with hard objects. We strongly recommend that a case be used to protect the edges. When installing or removing a tempered glass product, avoid using excessive force as this can damage the screen protector.


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The number of homeless people in the U.S. shrank from 2012 to 2013, according to a large government study that found the number of veterans and others who are homeless declined for the third straight year. But homeless numbers rose in New York and other states, according to the Department of Housing and Urban Development.
The study also found that nearly 20 percent of homeless people were in either New York City (11 percent of the U.S. total) or Los Angeles (9 percent).
The HUD study uses data from a count conducted by U.S. shelters on a single night, in which they reported how many people were using their facilities, and how many were left without shelter. For the most recent Annual Homeless Assessment Report, the data was collected last January.
The tally found that 610,042 people were homeless on that night, reflecting a drop of nearly 4 percent from 2012 to 2013, the agency says. Of that number, 36 percent — 222,197 people — were in families, representing a drop of 7 percent for that group.
More than a third of all homeless people (35 percent) were living in spots such as abandoned buildings and cars, or under bridges, the report says. As with all the data we're mentioning, that number includes children; nearly a quarter of America's homeless are under 18, according to HUD.
The HUD report saw continued progress from recent efforts to help two groups: military veterans and people who are chronically homeless.
"Based on data reported by more than 3,000 cities and counties, last January's one-night estimate reveals a 24 percent drop in homelessness among veterans," according to a HUD news release, "and a 16 percent reduction among individuals experiencing long-term or chronic homelessness since 2010."
In terms of changes in the homeless population in America, here's a breakdown from the study:
In announcing the report Thursday, officials credited the "Opening Doors" program, which pairs federal agencies with local and state initiatives, for helping to reduce the numbers of people who are chronically homeless, as well as the number of veterans who are homeless.
The advocacy group National Alliance to End Homelessness says that many small groups deserve some credit, as well.
"Communities across the country are to be commended," the organization said in its reaction to today's HUD release. "Federal funding sources dedicated to homelessness have not increased appreciably, with the exception of dollars targeted specifically toward veterans. Instead, it is local providers and local communities implementing effective strategies and targeting resources more efficiently."
According to HUD, the pairing of housing with support programs that provide aid in dealing with mental illness, substance abuse and other issues "not only ends homelessness for these vulnerable individuals, but also saves the taxpayer money by interrupting a costly cycle of emergency room visits, detoxes, and even jail terms."
"If we're going to end homelessness as we know it, we need a continued bipartisan commitment from Congress to break the cycle trapping our most vulnerable citizens between living in a shelter or a life on the streets," said HUD Secretary Shaun Donovan, who urged lawmakers to maintain their support for "proven strategies that are making a real difference."
Copyright 2021 NPR. To see more, visit https://www.npr.org.


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Chapter 26
Jesus expounds all things from the beginning to the end—Babes and children utter marvelous things that cannot be written—Those in the Church of Christ have all things in common among them. About A.D. 34.
1 And now it came to pass that when Jesus had told these things he expounded them unto the multitude; and he did expound all things unto them, both great and small.
2 And he saith: These scriptures, which ye had not with you, the Father commanded that I should give unto you; for it was wisdom in him that they should be given unto future generations.
3 And he did expound all things, even from the beginning until the time that he should come in his glory—yea, even all things which should come upon the face of the earth, even until the elements should melt with fervent heat, and the earth should be wrapt together as a scroll, and the heavens and the earth should pass away;
4 And even unto the great and last day, when all people, and all kindreds, and all nations and tongues shall stand before God, to be judged of their works, whether they be good or whether they be evil—
5 If they be good, to the resurrection of everlasting life; and if they be evil, to the resurrection of damnation; being on a parallel, the one on the one hand and the other on the other hand, according to the mercy, and the justice, and the holiness which is in Christ, who was before the world began.
6 And now there cannot be written in this book even a hundredth part of the things which Jesus did truly teach unto the people;
7 But behold the plates of Nephi do contain the more part of the things which he taught the people.
8 And these things have I written, which are a lesser part of the things which he taught the people; and I have written them to the intent that they may be brought again unto this people, from the Gentiles, according to the words which Jesus hath spoken.
9 And when they shall have received this, which is expedient that they should have first, to try their faith, and if it shall so be that they shall believe these things then shall the greater things be made manifest unto them.
10 And if it so be that they will not believe these things, then shall the greater things be withheld from them, unto their condemnation.
11 Behold, I was about to write them, all which were engraven upon the plates of Nephi, but the Lord forbade it, saying: I will try the faith of my people.
12 Therefore I, Mormon, do write the things which have been commanded me of the Lord. And now I, Mormon, make an end of my sayings, and proceed to write the things which have been commanded me.
13 Therefore, I would that ye should behold that the Lord truly did teach the people, for the space of three days; and after that he did show himself unto them oft, and did break bread oft, and bless it, and give it unto them.
14 And it came to pass that he did teach and minister unto the children of the multitude of whom hath been spoken, and he did loose their tongues, and they did speak unto their fathers great and marvelous things, even greater than he had revealed unto the people; and he loosed their tongues that they could utter.
15 And it came to pass that after he had ascended into heaven—the second time that he showed himself unto them, and had gone unto the Father, after having healed all their sick, and their lame, and opened the eyes of their blind and unstopped the ears of the deaf, and even had done all manner of cures among them, and raised a man from the dead, and had shown forth his power unto them, and had ascended unto the Father—
16 Behold, it came to pass on the morrow that the multitude gathered themselves together, and they both saw and heard these children; yea, even babes did open their mouths and utter marvelous things; and the things which they did utter were forbidden that there should not any man write them.
17 And it came to pass that the disciples whom Jesus had chosen began from that time forth to baptize and to teach as many as did come unto them; and as many as were baptized in the name of Jesus were filled with the Holy Ghost.
18 And many of them saw and heard unspeakable things, which are not lawful to be written.
19 And they taught, and did minister one to another; and they had all things common among them, every man dealing justly, one with another.
20 And it came to pass that they did do all things even as Jesus had commanded them.
21 And they who were baptized in the name of Jesus were called the church of Christ.