text:
Download the Shri Krupa Tanjore Traditions App today to plan and schedule your classes! From this mobile App you can view class schedules, sign-up for classes, view ongoing promotions, as well as view the studio's location and contact information. You can also click through to our social pages! Optimize your time and maximize the convenience of signing up for classes from your device! Download this App today!
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subset: commoncrawl


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Do you want to Hard reset or Factory reset your Oppo A9 (2020) android mobile? Or Do you want to Remove Pin or Pattern lock when you forgot it?
Here are the best methods to Reset your Oppo A9 (2020) mobile. There are many methods available to Reset Android mobile. You can try the following methods one by one.
Reset deletes all your mobile data like Photos, Apps, and Settings etc. So backup all your mobile data before the reset.
Here you can
- Hard Reset Oppo A9 (2020).
- Factory reset Oppo A9 (2020) from settings.
- Oppo A9 (2020) unlock with Google find my device.
- Unlock Oppo A9 (2020) with Android Multi Tools.
- Bypass google account Oppo A9 (2020).
- Unlock Oppo A9 (2020) when you forgot password.
Oppo A9 (2020) Hard Reset
You will not recover any data after this reset method.
- Turn off your phone by holding down the Power button.
- Press and hold Volume Down Button + Power Button for a few seconds.
- Release both the buttons when you see 10-or Logo or Android Logo on the screen.
- Next, Select Language, Using Volume Button and confirm with Power button.
- After that, Choose Wipe data and cache option.
- Use the Volume Button to select option YES and press Power button to confirm.
- Finally, Select Reboot option.
- The Hard reset operation complete.
If above reset method did not work, check out this guide Android phone hard reset methods.
Reset With Find My Device – Google
You can easily reset or unlock your Oppo A9 (2020) Android phone with Google find my device remotely. You can not recover data after reset.
- Start by visiting the Google Find My Device on your system.
- Log in using the credentials of your Google Account.
- After logged in, There will be three different options Play Sound, Secure device and Erase device.
- Then Click on Erase device option, Then you will see Erase all data menu on your screen.
- Finally, Tap on the Erase option.
- You have successfully Reset your mobile.
Reset with Android Multi Tools
You can reset or wipe data of your Oppo A9 (2020) phone with Android multi tools. You can also reset Gmail and reboot your device.
- Turn on your Computer or Laptop and Open any Browser.
- Download the Android Multi Tools.
- After the installation, Open the Android Tool.
- After that, Enable USB debugging on your Mobile.
- Now, Press and hold the Volume Up + power key {Volume Down + Power Key} on your mobile.
- Connect your mobile to your Computer via USB when you see an Android boot on your mobile screen.
- Finally, Select Number 5 and press Enter to Reset your mobile.
- Reset Complete with Android Tools.
Oppo A9 (2020) Reset With Google Account
If your Android device uses an Android 4.4 system or less, you can reset your Mobile using your Google Account.
- Turn On your phone by holding down the Power button.
- Next, you need to do 5 or 6 wrong pattern attempts, Then will show Forgot password Option.
- After that select Forgot pattern option.
- Next, Type your email & password and Tap on the Sign in Option.
- Android will confirm your email and password.
- Then redirects you to a security page.
- Here you can change or disable your screen lock.
Oppo A9 (2020) Factory Reset from Settings
Here you can reset Oppo A9 (2020) from settings app. You need password to reset with this method. This method also deletes all your data but you have an option to backup your mobile data before the reset.
- First, Switch on your Oppo A9 (2020) smartphone.
- Next Open Settings Menu.
- After that, Select More Settings Option.
- Then go to Backup and Reset option.
- In this Step, Choose option Erase all Data.
- Next, you will see your device has finished formatting.
- Wait for a while, Reset done on your mobile.


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From NPR News, this is ALL THINGS CONSIDERED. I'm Audie Cornish.
And I'm Melissa Block.
In local TV news, one of the most basic ways to appeal to viewers is to constantly promise breaking news, but one station in Louisville, Kentucky, is taking a different approach. NPR media correspondent David Folkenflik tells us more.
DAVID FOLKENFLIK, BYLINE: The spot is for WDRB television in Louisville.
FOLKENFLIK: Deception? Bill Lamb is general manager at WDRB, the Louisville Fox affiliate.
BILL LAMB: We kind of looked around and saw that the other guys were playing a marketing game with breaking news, and we were taking an approach of better journalism, and we were hiring journalists who were better writers, better storytellers.
FOLKENFLIK: Lamb's station actually makes a 10-part promise.
LAMB: Well, we will not hype our product, and our promotion will always be truthful. We'll strive to present reporting that's bias free. You know, that's a difficult thing to do when human beings are putting together the news.
FOLKENFLIK: Lamb and his news director Barry Fulmer came up with this approach six years ago after they concluded their station's story on a school bus driver's arrest in her own car for DUI the night before, well, no laughing matter, was not news and not breaking. Only last month, however, did they start that promotional campaign, explicitly taking direct aim at Louisville's ratings leader, WLKY.
ANDREA STAHLMAN: We've built a position of leadership in the market based on our belief that, you know, Louisville news viewers think that breaking news and weather coverage is important, and that's what we deliver.
FOLKENFLIK: Andrea Stahlman is news director for WLKY, a station owned by the Hearst Company, which has promoted its brand across the country.
STAHLMAN: We cover what's happening in the community. We cover crime stories. We cover events. We do investigative pieces. I mean, we cover severe weather.
FOLKENFLIK: WDRB covers a lot of the same news as everyone else - crime, politics, traffic, weather and even an occasional salacious expose as well. Yet, around town, a half dozen people told me they liked what they heard from WDRB. I met Tommy Feldman(ph), a retiree, down at Louisville's Waterfront Park by the banks of the Ohio River.
TOMMY FELDMAN: I like what WDRB is doing...
FOLKENFLIK: You do.
FELDMAN: ...because I get very tired of the breaking news because it's not.
FOLKENFLIK: But TV consultant Dave Smith, CEO of SmithGeiger, says local stations have to convey urgency and maybe even be a little bit breathless because they now face so many new challenges, such as text alerts, Yahoo! News and Twitter.
DAVE SMITH: It's not a choice that the television industry made. It's not a choice that news departments or cable news channels made. It's a choice that the audience made. There's no way to stop this onward march of technology and how it's affecting the delivery of news and information.
FOLKENFLIK: Whatever the platform, Bill Lamb argues people are eager to discern a different flavor in their news diet, and so far, he says it's working. The station is preparing to build an extension for its newsroom to handle all the new hires. David Folkenflik, NPR News. Transcript provided by NPR, Copyright NPR.


text:
Pride 2022 Glasses Case
Regular price$65.00 Sale pricePride 2022 Glasses Case
Designer Leather Glasses Case
Designer Leather Glasses Case
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Care instructions
To ensure the leather print on your product is as durable as possible, we've worked hard refining our printing process and craftsmanship. As leather has a naturally textured surface, you may notice small surface differences. This is common for natural leather and leather printing. All leathers age naturally according to usage, and this can cause the print to wrinkle or fade slightly over time. It is possible the base color may show through the leather as it ages with wear. When not in use, we recommend storing your product in a protective dust bag or box to keep it looking its best. • Avoid prolonged exposure to extreme heat, sunlight, water, and chemical cleaners to maintain a bright and long-lasting print. • Avoid contact with light-colored fabrics or upholstery as the color may transfer. • While a light rain shower is unlikely to harm, we recommend protecting from rain. Should your product get wet, allow it to dry naturally away from direct heat. • To clean surface wipe only with a damp lint-free cotton cloth.


text:
Hire only best packers and movers in Badanpur Ahmedabad
Easiest way to hire from Top Packers and Movers in Badanpur Ahmedabad is call2shiftahmedabad.inCall2ShiftAhmedabad is an online directory where you can find a list of top Packers and Movers in Badanpur. These top companies are not only a good packing and moving service providers in Badanpur Ahmedabad but are also the most affordable and reliable shifting services providers in Badanpur Ahmedabad. Our top removal partners can help you in activities like Local House shifting, office relocation, bike & car transportation, domestic as well as international shifting, commercial shifting, warehousing & storage facility with an attractive price range. All you need to do is just tell us your shifting requirements in our contact form and sit relax because, after your query submission, we will be sharing your relocation requirements to top four local shifting service providers near you. They will give you a free quotation so that you can get a fair idea about the service and the price they are charging for their service.
Call2ShiftAhmedabad is a portal where you can find the best local packers and movers in Badanpur Ahmedabad. When you are planning to shift your office or home to a newer place which is in your current city then you will definitely be needing local packers and movers Badanpur who are available near to your location. At Call2ShiftAhmedabad, we only list best packers and movers in Badanpur so that you can easily find them and can hire them as soon as possible for household shifting or office relocation. Call2shiftAhmedabad is one of the best portals that provides information about the leading "verified packers and movers of Badanpur".
It's very hard to find the best suitable movers and packers in Badanpur Ahmedabad if you go online on google and search for them. You will find a large number of service providers on the internet that boasts that they are the best and affordable packers and movers Badanpur Ahmedabad. You will either visit each service provider's portal or you will select in one of the top search results. Ultimately compromising with your pocket and reliability of shifting service providers. They may or may not be the best packers and movers out there but we can assure you that you will only find the best packers and movers on call2shiftahmedabad.in. A single place to search for the most reliable Packers Movers in Badanpur. All of them are available at a reasonable price.


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What information is, or may be, collected form
As part of the registration process on the Site,
I OPTICAL may collect the following personally identifiable information about
you: Name including first and last name, alternate email address, mobile phone
number and contact details, Postal code, Demographic profile (like your age,
gender, occupation, education, address etc.) and information about the pages on
the site you visit/access, the links you click on the site, the number of times
you access the page and any such browsing information.
How do we Collect the Information ?
I OPTICAL will collect personally identifiable
information about you only as part of a voluntary registration process, on-line
survey or any combination thereof. The Site may contain links to other Web
sites. I OPTICAL is not responsible for the privacy practices of such Web sites
which it does not own, manage or control. The Site and third-party vendors,
including Google, use first-party cookies (such as the Google Analytics cookie)
and third-party cookies (such as the DoubleClick cookie) together to inform,
optimize, and serve ads based on someone's past visits to the Site.
How is information used ?
I OPTICAL will use your personal information to
provide personalized features to you on the Site and to provide for promotional
offers to you through the Site and other channels. I OPTICAL will also provide
this information to its business associates and partners to get in touch with
you when necessary to provide the services requested by you. I OPTICAL will use
this information to preserve transaction history as governed by existing law or
policy. I OPTICAL may also use contact information internally to direct its
efforts for product improvement, to contact you as a survey respondent, to
notify you if you win any contest; and to send you promotional materials from
its contest sponsors or advertisers. I OPTICAL will also use this information
to serve various promotional and advertising materials to you via display advertisements
through the Google Ad network on third party websites. You can opt out of
Google Analytics for Display Advertising and customize Google Display network
ads using the Ads Preferences Manager same will be applicable for other social
networking sites like Facebook. Information about Customers on an aggregate
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Customer transaction data and Customer demographic and location data may be
provided to partners of I OPTICAL for the purpose of creating additional
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With whom your information will be shared
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OPTICAL does not rent, sell or share your personal information and will not
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collection, use and distribution of your information ?
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OPTICAL servers are accessible only to authorized personnel and your
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Although I OPTICAL will endeavor to safeguard the confidentiality of your personally
identifiable information, transmissions made by means of the Internet cannot be
made absolutely secure. By using this site, you agree that I OPTICAL will have
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How can you correct inaccuracies in the
To correct or update any information you have
provided, the Site allows you to do it online. In the event of loss of access
details you can send an e-mail to: firstname.lastname@example.com
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I OPTICAL reserves the right to change or update
this policy at any time. Such changes shall be effective immediately upon
posting to the Site.
We are no way affiliated to any 3rd party ad
services like Facebook, Tiktok etc. We use those platforms for serving our ads.
Contact Information
South Dinajpur,West Bengal-733101


text:
We offer a Free quote and UK design service, get in touch today.
Video wall systems in Allerford TA24 8 involve a range of screens grouped together to form a large digital advertising screen. The professional LFV screens are designed specifically for video walls as this will allow advertisements run smoothly and actively. If your company is considering a range of marketing techniques, this could be a great option for you as all the displays are long lasting effective throughout the UK. No matter what your business has to offer, you are able to create a campaign that can run on our video-walls.
If you would like to receive more information regarding video walls closest to you, get in touch with us today. Our digital signage specialist's team are able to provide you with all the details you need in order to achieve the advertisements that suit you. Simply fill out the enquiry form provided and we will get back in touch as soon as possible.
Our high definition, LED back lit screens allow you to choose a design that perfectly suits your businesses advertising campaign. There are a wide range of colours for you to choose from and the reduced bezel design makes it a perfect choice for a large video-wall and control room displays. The superb high brightness displays deliver a crystal clear, crisp picture while at the same time offering exceptional energy savings. No matter what your business has to offer, we can offer you the specialist advertising campaigns using our quality digital signage. Simply fill out the enquiry form provided if you are interested in finding out more and would like to receive further details.
Whilst within a meeting room in your surrounding area, you will quite often need to collaborate with a variety of businesses and individuals across the UK. Our video walls can offer a visual assistance during this process to provide you with the key technology to help develop your business. We may offer you the finest image quality and highest reliability screens in order to ensure the message is given is presented to the audience in the best possible way.
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text:
create_aggregate (7) - Linux Manuals
create_aggregate: define a new aggregate function
CREATE AGGREGATE - define a new aggregate functionSYNOPSIS
CREATE AGGREGATE name ( input_data_type [ , ... ] ) ( SFUNC = sfunc, STYPE = state_data_type [ , FINALFUNC = ffunc ] [ , INITCOND = initial_condition ] [ , SORTOP = sort_operator ] ) or the old syntax CREATE AGGREGATE name ( BASETYPE = base_type, SFUNC = sfunc, STYPE = state_data_type [ , FINALFUNC = ffunc ] [ , INITCOND = initial_condition ] [ , SORTOP = sort_operator ] )
CREATE AGGREGATE defines a new aggregate function. Some basic and commonly-used aggregate functions are included with the distribution; they are documented in in the documentation. If one defines new types or needs an aggregate function not already provided, then CREATE AGGREGATE can be used to provide the desired features.
If a schema name is given (for example, CREATE AGGREGATE myschema.myagg ...) then the aggregate function is created in the specified schema. Otherwise it is created in the current schema.
An aggregate function is identified by its name and input data type(s). Two aggregates in the same schema can have the same name if they operate on different input types. The name and input data type(s) of an aggregate must also be distinct from the name and input data type(s) of every ordinary function in the same schema.
An aggregate function is made from one or two ordinary functions: a state transition function sfunc, and an optional final calculation function ffunc. These are used as follows:
sfunc( internal-state, next-data-values ) ---> next-internal-state ffunc( internal-state ) ---> aggregate-value
PostgreSQL creates a temporary variable of data type stype to hold the current internal state of the aggregate. At each input row, the aggregate argument value(s) are calculated and the state transition function is invoked with the current state value and the new argument value(s) to calculate a new internal state value. After all the rows have been processed, the final function is invoked once to calculate the aggregate's return value. If there is no final function then the ending state value is returned as-is.
An aggregate function can provide an initial condition, that is, an initial value for the internal state value. This is specified and stored in the database as a value of type text, but it must be a valid external representation of a constant of the state value data type. If it is not supplied then the state value starts out null.
If the state transition function is declared ``strict'', then it cannot be called with null inputs. With such a transition function, aggregate execution behaves as follows. Rows with any null input values are ignored (the function is not called and the previous state value is retained). If the initial state value is null, then at the first row with all-nonnull input values, the first argument value replaces the state value, and the transition function is invoked at subsequent rows with all-nonnull input values. This is handy for implementing aggregates like max. Note that this behavior is only available when state_data_type is the same as the first input_data_type. When these types are different, you must supply a nonnull initial condition or use a nonstrict transition function.
If the state transition function is not strict, then it will be called unconditionally at each input row, and must deal with null inputs and null transition values for itself. This allows the aggregate author to have full control over the aggregate's handling of null values.
If the final function is declared ``strict'', then it will not be called when the ending state value is null; instead a null result will be returned automatically. (Of course this is just the normal behavior of strict functions.) In any case the final function has the option of returning a null value. For example, the final function for avg returns null when it sees there were zero input rows.
Aggregates that behave like MIN or MAX can sometimes be optimized by looking into an index instead of scanning every input row. If this aggregate can be so optimized, indicate it by specifying a sort operator. The basic requirement is that the aggregate must yield the first element in the sort ordering induced by the operator; in other words:
SELECT agg(col) FROM tab;must be equivalent to:
SELECT col FROM tab ORDER BY col USING sortop LIMIT 1;Further assumptions are that the aggregate ignores null inputs, and that it delivers a null result if and only if there were no non-null inputs. Ordinarily, a data type's < operator is the proper sort operator for MIN, and > is the proper sort operator for MAX. Note that the optimization will never actually take effect unless the specified operator is the ``less than'' or ``greater than'' strategy member of a B-tree index operator class.
- name
- The name (optionally schema-qualified) of the aggregate function to create.
- input_data_type
- An input data type on which this aggregate function operates. To create a zero-argument aggregate function, write * in place of the list of input data types. (An example of such an aggregate is count(*).)
- base_type
- In the old syntax for CREATE AGGREGATE, the input data type is specified by a basetype parameter rather than being written next to the aggregate name. Note that this syntax allows only one input parameter. To define a zero-argument aggregate function, specify the basetype as "ANY" (not *).
- sfunc
- The name of the state transition function to be called for each input row. For an N-argument aggregate function, the sfunc must take N+1 arguments, the first being of type state_data_type and the rest matching the declared input data type(s) of the aggregate. The function must return a value of type state_data_type. This function takes the current state value and the current input data value(s), and returns the next state value.
- state_data_type
- The data type for the aggregate's state value.
- ffunc
- The name of the final function called to compute the aggregate's result after all input rows have been traversed. The function must take a single argument of type state_data_type. The return data type of the aggregate is defined as the return type of this function. If ffunc is not specified, then the ending state value is used as the aggregate's result, and the return type is state_data_type.
- initial_condition
- The initial setting for the state value. This must be a string constant in the form accepted for the data type state_data_type. If not specified, the state value starts out null.
- sort_operator
- The associated sort operator for a MIN- or MAX-like aggregate. This is just an operator name (possibly schema-qualified). The operator is assumed to have the same input data types as the aggregate (which must be a single-argument aggregate).
The parameters of CREATE AGGREGATE can be written in any order, not just the order illustrated above.
CREATE AGGREGATE is a PostgreSQL language extension. The SQL standard does not provide for user-defined aggregate functions.


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28 May, 2023
Restoration of a pro-active trade policy
Congress in Stockholm, Sweden, May 2023
Congress in Stockholm, Sweden, October 2008
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text:
Merlin's weekly podcast with Dan Benjamin. We talk about creativity, independence, and making things you love.
Merlin's weekly podcast with Dan Benjamin. We talk about creativity, independence, and making things you love.
"What's 43 Folders?"
43Folders.com is Merlin Mann's website about finding the time and attention to do your best creative work.
Writing sensible email messages
Merlin Mann | Sep 19 2005
As we've seen before, getting your inbound email under control will give you a huge productivity boost, but what about all the emails you send? If you want to be a good email citizen and ensure the kind of results you're looking for, you'll need to craft messages that are concise and easy to deal with. First: Understand why you're writingBefore you type anything into a new message, have explicit answers for two questions:
If you can't succinctly state these answers, you might want to hold off on sending your message until you can. People get dozens, hundreds, even thousands of emails each day, so it's only natural for them to gravitate toward the messages that are well thought-out and that clearly respect their time and attention. Careless emails do not invite careful responses. Think through your email from the recipient's point of view, and make sure you've done everything you can to try and help yourself before contacting someone else. If it's a valuable message, treat it that way, and put in the time to making your words count. Get what you needAlthough the possible topics and content of messages are theoretically endless, I'd propose that there are really just three basic types of business email.
It should be clear to your recipient which type of email yours is; don't bury the lede. Get the details and context packed into that first sentence or two whenever you can. Don't be afraid to write an actual "topic sentence" that clarifies a) what this is about, and b) what response or action you require of the recipient. This isn't the place to practice your stand-up act. Keep it pithy, and assume that no one will ever read more than the first sentence of anything you write. Making that first sentence strong and clear is easily the best way to interest your recipient in the second sentence and beyond. Write a great Subject lineYou can make it even easier for your recipient to immediately understand why you've sent them an email and to quickly determine what kind of response or action it requires. Compose a great "Subject:" line that hits the high points or summarizes the thrust of the message. Avoid "Hi," "One more thing...," or "FYI," in favor of typing a short summary of the most important points in the message:
In fact, if you're relating just a single fact or asking one question in your email, consider using just the subject line to relate your message. As I've mentioned before, in some organizations, such emails are identified by adding Sadly, good email subjects have become something of a lost art, especially among more recent additions to the Interweb. It's a pity, because you're far more likely to get a favorable response from a busy person when they can quickly grok your message. Brevity is the soul of...getting a responseIt's completely depressing to check your email at 4:55 in the afternoon to discover a gothic novel of a message waiting for you, spilling down your screen the distance of 2 or 3 scrolling pages. It's certainly not the kind of thing that excites the desire to engage and respond. I mean just look at all that! So, although—in typical Merlin fashion—I have only anecdotal evidence and hunches to prove this point, I'd wager that there's one visual trick most likely to improve your message's success: fit it onto one screen with no scrolling. There's a reason those web ads placed "above the fold" cost a lot more than the ones stuck down at the bottom; it's the only part of the page that you're virtually assured that anyone will see. Whenever you can, try to distill your beautiful epistle down to just one or two points about a given topic, and then whittle that down to the point where there's plenty of white space left underneath your closing. Got more to say? Put it in separate emails with—again—excellent Subject lines, and a descriptive, concise opener. What's the action here?If your message includes any kind of request—whether for a meeting, a progress update, a pony ride, or what have you—put that request near the top of the message and clearly state when you will need it. Do not, under any circumstances, assume that your overwhelmed recipient will take the time to sift through your purple prose for clues about what they're supposed to be doing for you. Depending on the style of your team and the volume of mail they create, you might even consider adding functional text headers to the top of the body outlining the exact nature of the message. This email is: [ ] actionable [x] fyi [ ] social Response needed: [ ] yes [x] up to you [ ] no Time-sensitive: [ ] immediate [ ] soon [x] none Sure, it's geeky, but how many minutes have you wasted panning through a sloppy "project update" email only to completely miss the changed deadline or work request buried in the penultimate paragraph? Remove the guesswork from your messages by thinking of them like friendly, civil work orders; you must not be afraid to ask for what you want, especially if you have any desire to actually have the recipient give it to you. More good ideas
[Thanks to Cory for exchanges and thoughts that contributed to this.] POSTED IN:
A structured writting class I...Submitted by JonathanPeterson (not verified) on September 20, 2005 - 2:42am.
A structured writting class I took had a good suggestion re: emails that I'll add. When you have multiple things in an email (say a project status), write a concise summary graph followed by an index with the major items: 1) Ad Copy Delayed 2) Server Configuration Complete 3) Awaiting Client sign-off Then use the same topics as section headers - that way a large list of readers can quickly jump to the things that interest them. » POSTED IN:
EXPLORE 43Folders | THE GOOD STUFF |


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You have found a bug or you have an idea for a cool new feature? Contributing code is a great way to give something back to the open source community. Before you dig right into the code, there are a few guidelines that we need contributors to follow so that we can have a chance of keeping on top of things.
We accept Pull Requests via GitHub. The developer mailing list is the main channel of communication for contributors.
There are some guidelines which will make applying PRs easier for us:
git diff --check
before committing.[MPMD-XXX] - Subject of the JIRA Ticket Optional supplemental description.
mvn -Prun-its verify
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text:
Previous Lesson
Complete and Continue
52 Day Business Apprenticeship
Course Introduction
Platform Induction
Meet Your Instructor
Elephant & Co's Teaching Team
Program Outline
Getting Started
Welcome (1:41)
The Future (Article)
Goal Setting
Goal Setting (Watch) (6:00)
Goal Setting (Activity)
E4 Theory: What is Elephant & Co all about?
Welcome (eBook)
E1: Thinking (Watch) (5:30)
E2: Leadership (Watch) (11:24)
E3: Innovation (Watch) (11:30)
E4: Growth
10x Land: The power of growing your business by 10! (eBook)
Goal Setting: Touch Point
Module Review
Module 3: Thinking
What is thinking? (Watch/Activity) (5:32)
History of Thinking (Watch/Activity) (8:49)
Do schools kill creativity? (Watch) (20:03)
Thinking vs Thoughting (Article)
Thinking vs Thoughting (Watch/Activity) (7:33)
Thinking Project: 10 Key Voices
How do we change our thinking so that we can grow?
Defend2Escape (Tool)
D2E (Activity)
The Good, The Bad, The Better
GBB (Activity)
Why 10? (Watch) (0:55)
Module in Review
Module 4: Leadership
Welcome (1:56)
The 5 Most Important Laws of Leadership (eBook)
How do people learn? (Article)
Learning Pyramid (Watch) (1:52)
Leadership (Activity)
Empowering your team (Activity)
Why is C2C important? (Watch/Activity)
How to lead the change (Article)
UI2UC (Activity)
Practice, Rehearsal, Repetition (Watch) (2:44)
PRR for UI2UC
Leadership Module: Checkpoint
Power of Why!
The Golden Circles (Watch) (18:34)
Why, How, What (Activity)
The Power of Storytelling (eBook)
Create your story! (Activity)
Storytelling Challange
Sense Making (Article) (2:08)
How do you sense make (Activity)
Module in Review
Module 5: Innovation
What is Innovation
Innovation and your business (Watch/Activity) (2:03)
Types of Innovation (Article)
Innovation Project: 'Your Business Innovation Strategy'
D2E in your Industry (Activity)
How do you begin to Innovate?
10 Possible Futures (Tool)
Buck a Day: 'BAD' (Tool) (1:42)
Innovation Tools in Action: Case Study (Watch) (3:58)
10PF and B.A.D (Activity)
Innovation Module: Checkpoint
Analogue 2 Digital: A2D
Business Lifecycle (2:47)
Innovation Culture (1:58)
What are the conditions you need to create? (Activity)
Module in Review
Bonus Lesson: How to fund your Innovation!
Module 6: Growth
Back to Basics: Customer Service
WOMBATS (Activity)
Buyer 2 Seller Relationship
Who is your customer (Activity)
Current Value 2 Potential Value: CV2PV (Watch) (10:43)
CV2PV (Activity)
Check 2 Checkmate (Tool/Watch) (6:20)
The 7P's (2:21)
What are your 7P's (Activity)
Sales Pitch (Activity)
Module in Review
Course Summary
Bringing E4 Together (9:31)
Goal Reflection
Teach online with
Types of Innovation (Article)
Lesson content locked
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For pallet rack solutions in the Rancho Cordova area, turn to Rancho Cordova Pallet Racking for a vast selection of top-quality new and used racks and other racking equipment.
Standard Pallet Racking Systems
Rancho Cordova Pallet Racking offers a wide selection of used pallet rack. Used frames ranging from 4′ to 18′ tall, and varying from 24″ to 48″ deep. Used beams from light to heavy duty, ranging from 48″ to 12′ in length. We also offer replacement parts and additions to your standing rack. Please call or email us for your used pallet rack needs, or if you have used pallet rack for sale.
Mezzanine Flooring Systems
Mezzanines are often used in warehouses and distribution centers as an efficient way to utilize the available height, otherwise known as cubic space, in order to consolidate operations into a single area or possibly to free up valuable floor space for other operations. Many times, storage mezzanines are used as the levels of a pick module.
Conveyor Belts
Belt conveyors consists of two or more pulleys with a continuous loop of material, known as the conveyor belt, rotating about them. Primarily, one of the pulleys is powered, moving the belt and the material on the belt forward. The powered pulley is referred to as the drive pulley, while the unpowered pulleys are called idle pulleys.
Modular Offices
Solving your modular space needs begins with a partner who understands the concept of accountability. Rancho Cordova Pallet Racking integrates building design and construction into one hassle-free solution during your permanent building process. While on-site, we can provide other facilities to make the building process more comfortable and efficient for all with the use of Mobile Offices, Ground Level Offices, Containers, Blast Resistant Buildings and Value-Added Products if needed.
Fork Lifts
Rancho Cordova Pallet Racking can provide you with whatever type of forklift you need for your warehouse and material handling needs. Top quality brands, a wide range or prices, and our extensive experience help us to get the right fork lift for you!
Contact Form
We would love to hear from you! Please fill out this form and we will get in touch with you shortly.


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2012 Election Day: Obama Wins Second Term
UPDATE 11:20: The networks have announced that Barack Obama will be reelected to a second term, after wrapping up the state of Ohio.
The 2012 presidential election between Barack Obama and Mitt Romney will finally conclude tonight, as voters head to their local polls to choose who gets to sleep in the White House on January 20, 2013. We'll be following all the results very closely, adding the latest news as states close their polls and announce their winners.
Watch this post for updated information—election results, Senate races, ballot measures, battleground-state news—throughout the night:
After the 11 p.m. poll closings, here's what we know:
• Obama wins: Ohio, Nevada, Colorado, Iowa, California, Washington, Minnesota, New Hampshire, Wisconsin, Pennsylvania, Michigan, New York, New Mexico, New Jersey, Illinois, Maryland, Delaware, Rhode Island, Connecticut, Massachusetts, Maine, Washington (D.C.), Vermont
• Romney wins: North Carolina, Missouri, Idaho, Arizona, Utah, Montana, Texas, Louisiana, Kansas, Nebraska, North Dakota, South Dakota, Wyoming, Mississippi, Alabama, Georgia, Arkansas, Tennessee, Oklahoma, West Virginia, South Carolina, Kentucky, Indiana
• Too close to call at this time: Florida, Virginia
Other news:
• Virginia Senate: Democrat Tim Kaine has defeated Republican George Allen
• Indiana Senate: Democrat Joe Donnelly has defeated Republican Richard Mourdock
• Missouri Senate: Democrat Claire McCaskill has defeated Republican Todd Akin
• Massachusetts Senate: Democrat Elizabeth Warren has defeated Republican Scott Brown
• Connecticut Senate: Democrat Chris Murphy has defeated Republican Linda McMahon
• 10 biggest Senate races to watch tonight: Indiana, Connecticut, Virginia, Massachusetts, Missouri, Arizona, Wisconsin, Montana, North Dakota, Nevada [Guardian]
• Key ballot measures up for a vote tonight [Washington Post]
• An exhaustive list of predictions by pundits [NY Mag]
• Michigan voter appears to die, comes back to life, asks, "Did I vote?" [Detroit News]
• If vote totals are particularly close in Ohio, we may not know the winner in the Buckeye State—or nationwide—for several weeks. [New York Times]
• One electronic voting machine in Pennsylvania was changing Obama votes to Romney votes. The machine has been removed from use. [TheFW]
• The top of the Empire State Building will add blue lights (Obama) and red lights (Romney) as each candidate gets closer to the required 270 electoral votes. [CNN]
• In the very first official election returns, the town of Dixville Notch, New Hampshire, showed a tie: five votes each for Obama and Romney. The town has correctly picked the presidential winner in each of the last three cycles. [CNN]
Polls start closing at 6 p.m. and continue to do so every half hour or so across the country. Some states are almost certain to go for one particular candidate or the other, so we'll be more closely watching the returns on swing states like Ohio, Florida and Virginia. There's no telling when those states will be able to declare their winner, but we'll keep an eye on things and post the results here as soon as we can.
We will fill in the map at the bottom of this post as each state releases its final numbers or the news networks decide enough information is available to make a call either for Obama or Romney.


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The man who accused the voice of Elmo of having sex with him while he was underage has recanted his allegations.
According to The New York Times, which broke the story, the law firm representing the man said he and Kevin Clash had a sexual relationship but it "was an adult consensual relationship."
The Times quotes a Clash spokesman as saying that he was "relieved that this painful allegation has been put to rest. I will not discuss it further."
Sesame Workshop, the production company behind Sesame Street, said it was "pleased that this matter has been brought to a close."
The Workshop announced yesterday that Clash had been given a leave of absence to deal with the accusations.
"We are happy that Kevin can move on from this unfortunate episode," the Workshop said in a statement.
Copyright 2021 NPR. To see more, visit https://www.npr.org.


text:
All orders can be canceled until they are processed and shipped. Once the packaging and shipping process has started, it can no longer be canceled.
If you do not want the product you received, you are required to contact us via email at email@example.com within 14 days of receiving the item. After the claim is approved, you must return the item to our warehouse at your own expense and the item must be unused;
In the case you receive a damaged or incorrect product, you are required to submit photo evidence to firstname.lastname@example.com within 14 days of receiving the item. If the claim is approved, a refund will be issued.
If the product packaging is damaged but the product itself is intact, you must submit a claim to the shipping carrier directly.
Missing order. In the case that a package is delivered (based on tracking number update) but you did not receive the item, you must submit a claim to the shipping carrier directly.
If you experienced any of the above scenarios, you must report the issue within 14 days of receipt. Otherwise, you agree that the product is deemed delivered and satisfactory.
Your order does not arrive due to an incorrect address provided by you;
Your order does not arrive due to an exceptional circumstances beyond our control (e.g. delayed by a natural disaster)
If you want to initiate a return, exchange, or refund, please complete the following steps:
Have any other questions? Please feel free to reach out to email@example.com


text:
Loading Map....
Date(s) - Feb 13 2018
6:00 pm - 7:00 pm
El Dorado West
Categories No Categories
This full-body workout will boost your metabolism, blast away inches and help you Become Lean, Agile, Strong, Toned with the perfect combination of strength, agility/sports moves and cardio. Bodyweight exercises and fitness toys make this class fun and effective. All levels welcome. Come be challenged! Bring dumbbells, resistance tube and mat.
Cost: $11 Walk In
Contact Tami at email@example.com


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Understand the default port configuration
A port is an endpoint of communication in an operating system that identifies a specific process or a type of service. Bitnami stacks include several services or servers that require a port.
IMPORTANT: Making this application's network ports public is a significant security risk. You are strongly advised to only allow access to those ports from trusted networks. If, for development purposes, you need to access from outside of a trusted network, please do not allow access to those ports via a public IP address. Instead, use a secure channel such as a VPN or an SSH tunnel. Follow these instructions to remotely connect safely and reliably.
Port 22 is the default port for SSH connections.


text:
Nicorette Lozenge (Nicotine Bitartrate Dihydrate)
Nicotinell Lozenge Mint
2mg Lozenge
Product of UK/EU. Shipped from United Kingdom of Great Britain and Northern Ireland. Nicorette Lozenge is also marketed internationally under the name Nicotinell Lozenge Mint.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.


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I haven't much time this morning, so this is less a post than a teaser. My apologies.
The second public shooting day for 1,000 Knitters, at the Stitches Midwest 2007 Market, was a rousing success. Between 10 am and 3:30 pm (I was having such a good time I forgot to stop at three o'clock) about sixty knitters added their stitches to the scarf, including a few folks whose names you will likely recognize.
More on that tonight or tomorrow, but one thing can't wait: several thank-yous.
A tip of the lens to:
- XRX, the fine folks who run Stitches, for allowing me to wield my camera in the Market. Lisa from Marketing, you totally did not have to spend time working on my behalf with the legal department; but you did, so your name goes on the project honor roll.
- The dear people of Jimmy Beans Wool, who sponsored the shoot and went above and beyond by keeping me well-watered while I worked. They also allotted me the invaluable services of the wonderful Jeanne, who not only kept things running smoothly during busy moments but persuaded timid, yarn-crazed knitters who'd never heard of me to stop shopping so I could photograph them.
- Jan, who I believe is blogless (if you're not, honey, send me the link) who sat for her portrait early in the day and went back to work at Leslye Solomon's booth, but continued to proselytize. If I heard "Jan sent me" once, I heard it a dozen times.
- My buddy Stash Haus who sat for a portrait, came by periodically to see how I was doing, and then hung around until the very end and drove the exhausted photographer and his sink-the-Titanic load of equipment back to Boystown.
- All of you who sat. You are making it happen. How can I ever thank you?


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Heavy Equipment Moving Streamwood IL | Heavy Hauling
Call Illinois Vehicle Transport 1-773-234-6669
Watch our heavy equipment moving Streamwood IL videos on Youtube.com – Heavy Equipment Transport
Heavy equipment moving Streamwood IL involves specialized trailers that can withstand extreme loads, sometimes very unevenly distributed and sometimes irregular shape. Railroads are utilized for heavy equipment moving as well which can significantly bring down transportation cost if proper arrangements are put in place.
While logistics of moving heavy equipment with trucks are more complex than the railroad transportation, usually because of its dimensions, the process is also quicker than moving heavy equipment by train.
Some typical examples of heavy equipment moving Streamwood IL that often require specialized haulers are:
- industrial gear
- tractors
- bulldozers
- construction machinery
- plow trucks
- forklifts
- farm equipment
- cranes, etc.
To determine your heavy equipment moving Streamwood IL cost you need to provide the carrier with its dimensions and weight. Even without the manual you can find that information by going to this website – http://www.ritchiespecs.com/– and browsing through their inventory.
With that information in hand your heavy equipment moving company in Streamwood IL will be able to determine the best possible transportation route and form: special trailer, towing, train transport, or combination. Additional questions will arise for the international shipping quotes.
There are two types of approaching your heavy equipment moving company in Streamwood IL; directly or by using a broker. Each one of the approaches can be beneficial for you and it's difficult to predict the outcome of the relationship because there are many variables involved.
In case you get a quick and perfect match by dealing directly with some heavy equipment moving company in Streamwood IL, who might be able to provide exactly the right type of transportation for your piece of equipment and within your time frame, you should be OK.
On the other hand, using a broker for your heavy equipment moving in Streamwood IL opens up much larger and more flexible market of carriers ready to serve you sometimes immediately. You may also be able to negotiate or simply pick more favorable quote from multiple offers. In either case, check their record, verify credentials, and ask if it is possible to contact their previous clients. It doesn't matter if your heavy equipment moving is local, across the US, or you're shipping it overseas; get to know your transportation provider.
There are a few steps you should take while preparing for your heavy equipment moving day in Streamwood IL: Being ready when you shipper arrives for equipment pickup or to drop it off will save everyone a lot of aggravation and sometimes money.
- Any heavy equipment (or its components) that might be exposed to harmful weather conditions during transportation should be protected. The manufacturer's manual usually covers heavy equipment moving preparation procedures such as draining some fluids (to prevent freezing), securing equipment's components that are likely to become loose during transport, disconnecting power supplying batteries, and / or protecting parts that might be exposed to excessive heat while en route to its destination.
- Oversize heavy equipment moving in Streamwood IL may require special permits that must be issued by a variety of local agencies, and states your heavy equipment will be moving through. Make sure that you bring this up and consult it with your transportation provider to expedite paperwork preparation in time for the scheduled departure.
- Request insurance information from the carrier, make sure that it is sufficient to cover your loses in case of an accident. Purchase additional insurance policy if necessary.


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Recruiting Agent in Panama for EPS Cutting Machine
Latest News:! Recruitment agent for EPS Cutting Machine, we can offer full tech support for Panama Agent , and bottom price. one region limit one agent! This new valid untill 2019/2/28.
Wny be Agent of eps-cutting-machine.ecobd2.com?
eps-cutting-machine.ecobd2.com is a leading supplier of All Kinds of EPS Cutting Machines, be out agent, you can enjoy the bottom price in the world, and top quality products. EPS Cutting Machine is a very good products, which can used to Mold industry: casting mold, automobile, ship, yacht, aviation industry, rail transportation etc. Musical instruments: large 3D curved surface and shape processing, if you are interested in the agent of EPS Cutting Machine, welcome to contact us.
Note: in Panama limit one agent, welcome to contact EPS Cutting Machine online support team.
Click Here look the details of :EPS Cutting Machine
What is EPS Cutting Machine?
Cause the nichrome wire can be heated by the electricity device.So,it can melt and cut the expanded polystyrene foam.NiChrome Wire (NiCr) is also called hot wire.It is best in working as cutting foam.Because it is resistant to corrosion and oxidation,and it can reach high temperature in just seconds.The NiChrome wires can be with high tensile strength and high melting points.It has perfect balance between energy requirement and good tensile strength.We can see their application in many eps foam cutting machines.
What's the responsibility of the Agent of EPS Cutting Machine in Panama?
The responsibility of the Agent of EPS Cutting Machine in Panama should help us sell EPS Cutting Machine, and offer tech support for EPS Cutting Machine customers, help us keep a good relationship with EPS Cutting Machine customers.
Related Post
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why you need manufacturers install machines
What CNC system can do for cutting machine
Recruiting Agent in Comoros for EPS Cutting Machin...
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Digital Creative Marketing Inc. is a results-driven digital marketing & web design company based in Massachusetts. We help businesses with creative solutions across the United States. We specialize in Branding, Social Media Marketing, Web Design, SEO, Advertising, Lead Gen, & Content Production. Our mission is to help small businesses thrive online and grow with modern, strategic, and creative digital marketing.
We Specialize in Digital Marketing & Web Design for Landscaping & Construction Companies, Dental Clinics, Nonprofits, Home Service Companies, Food Industry, & General Contractors.
Branding, Web Design, SEO, Social Media Marketing, Advertising, and Content Production.
Digital marketing for any business requires a broad set of talent, tools, and strength to succeed in today's digital world. Let our team take care of the heavy lifting while we work with you to identify which services will benefit you the most and how we can maximize your reach with each marketing channel.
Our recent web design & development work
J&E Landscape Construction
J&E Landscape Construction
Tasca Restaurant
All-Pro Window Cleaning
J&E Landscape Construction
Attika Restaurant
Featured Projects
Add paragraph text. Click "Edit Text" to customize this theme across your site. You can update and reuse text themes.
Digital Creative Marketing is your one-stop company for all your Digital Marketing needs.
Branding & Strategy
Our design experts use a combined strategy and branding approach to create a successful brand strategy for your business. Telling your story isn't enough when you aren't projecting it to the right people. Therefore, our team will work alongside your team to conceptualize your brand's narrative that succinctly articulates the "Who" and the "Why" in a way that will drive you to reach your business goals.
We understand that every business has unique needs, and levels of support may vary. That's why we offer bundled solutions, each with a distinct set of services and features, to overcome your specific barriers and unleash your full-funnel growth potential.
Contact us today to get started on your Branding and Strategy in Woburn
Looking to learn more about Digital Creative Marketing and how we can work together? We're happy to help you understand what solutions we offer specific to your needs and suggest what you should focus on. Use our general inquiry form to schedule a time to chat with one of our marketing experts. You can expect a response within 24 hours.


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Vacations To Go is America's clearinghouse for deeply discounted cruises. Since our founding in 1984, we have provided more than eight million savvy shoppers with a dream vacation at a fraction of the regular price.
Vacations To Go is the largest seller of cruises worldwide and is among the largest for every cruise line. Click here to read what cruise line executives have to say about Vacations To Go's exceptional customer service and experience.
Best of all, our customers love us! Click here to read current reviews of Vacations To Go from customers who have recently cruised.
Vacations To Go is a fully accredited travel agency and a member in good standing of the International Airlines Travel Agent Network (IATAN) and the Cruise Line International Association (CLIA).


text:
- What are cookies?
- How do we use cookies?
- Cookies used on our site
- How to delete cookies or control them
[divider type="stripes" margin="20px 0 20px 0" ]
Since 26th May 2012, all UK websites need to comply with the EU E-Privacy Directive 2009/136/EC. Cookies are only a small part of this directive, and whilst you are still allowed to use cookies on a website, it must be made clear to visitors to your site that cookies are being used. A message or warning must be displayed so that the visitor is aware of them.
At the top of our website we have displayed a message to warn you that our website makes use of cookies and that one has already been set. By displaying this message we hope that we are providing you with the information you require about our use of cookies, and presenting you with the option to consent to their use. This message will be displayed until such time as you agree to our site using cookies by clicking on the continue button.
1.What is a cookie?
A cookie is a small amount of data, often including a unique identifier, sent to the browser of your computer or mobile phone (referred to here as a "device") from a website's computer. It is stored on your device's hard drive. Each website can send its own cookie to your browser if your browser's preferences allow it. To protect your privacy, your browser only permits a website to access the cookies it has already sent to you, and not the cookies sent to you by other websites. Many websites do this whenever a user visits them to track online traffic flows.
On the Channel Digital website, our cookies record information about your online preferences so we can tailor the site to your interests. You can set your device's preferences to accept all cookies, notify you when a cookie is issued, or not receive cookies at all. Selecting the last option means you will not receive certain personalised features, which may result in you being unable to take full advantage of all the website's features. Each browser is different, so please check the "Help" menu of your browser to learn how to change your cookie preferences.
During the course of any visit to our website, every page you see, along with a cookie, is downloaded to your device. Many websites do this because cookies enable website publishers to do useful things like find out whether your device (and probably you) has visited the website before. On a repeat visit this is done by the website's computer checking to see, and finding, the cookie left there on the last visit.
2.How do we use cookies?
Information supplied by cookies can help us analyse the profile of our visitors, which helps us provide you with a better user experience. For example, if on a previous visit you went to our marketing pages, we might find this out from your cookie and highlight marketing information on subsequent visits.
Third party cookies on our pages
Please note that during your visits to our website you may notice some cookies which are unrelated to us. When you visit a page with content embedded from, for example, YouTube or Flickr, you may be presented with cookies from these websites. We do not control the dissemination of these cookies. You should check the third party websites for more information about these.
3.Cookies used on our site
We only use cookies to help us continuously improve our website and maintain a nice browsing experience for our visitors. Here is a list of cookies used on this website:
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- Session cookie - this is a standard cookie just to remember user preferences (like font size and saves you logging in every time you visit)
4.How to delete cookies or control them
This site will not use cookies to collect personally identifiable information about you. However, if you wish to restrict or block cookies set by this or any other website, you can do this through your browser settings. The Help function within your browser should tell you how.
Alternatively, you may wish to visit www.aboutcookies.org which contains comprehensive information on how to do this for a wide variety of browsers. You will also find details on how to clear cookies from your computer as well as more general information about cookies. For information on how to do this on your mobile phone's browser, you will need to refer to your handset manual.


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Previous Lesson
Complete and Continue
The Dynamic Workout Design Training Black Book
Welcome To The Dynamic Workout Design Training Black Book!
Welcome To The Training Black Book! (0:58)
It's Not Just About Smashing People!
It's Easy To Create A Hard Workout... (1:17)
It All Comes Down To…WHO Is The Workout For?
Workouts Should Fit YOUR Needs! (2:24)
Getting Started Designing Workouts - Set A Schedule
Why Setting A Schedule Comes First (2:04)
Breaking Down Workout Variables - Reps, Sets and MORE!
What Are Training Variables? (2:52)
Reps or Repetitions
Weights And Loads
Training Duration and Frequency
Using The Training Variables
Test Your Knowledge!
Energy Systems, Interval Training And What Really Is HIIT?
Let's Talk About Conditioning And "Cardio" Workouts... (7:16)
What Is "Cardio" Really?
The 3 Energy Systems
Interval Training Vs. Steady-State Cardio
What Is Steady-State Cardio? The Pros And Cons
What Is Interval Training? The Pros And Cons
The Different Types Of "Rest"
Test Your Knowledge!
Exercise Selection - Picking The "Right" Moves
How Do You Pick The "Right" Moves? (12:21)
When And Why To Use Compound, Hybrid And Isolation Exercises
Unilateral vs. Bilateral Exercises - Pros and Cons
Planes Of Motion And Fundamental Movement Paterns
Loads, Variations And Tempos - Changing Up How Exercises Challenge You
Can You Build Strength And Muscle With Just Bodyweight Exercises?
Choosing Your Exercise Order - Why It Matters
Test Your Knowledge!
Experimenting With Work Designs
There's More Than One Way To Design A Workout (1:54)
Using The Workouts
The Warm Up Formula
Why You Shouldn't Skip The Warm Up (5:00)
Breaking Down The Warm Up: Foam Rolling
Breaking Down The Warm Up: Dynamic Stretching
Breaking Down The Warm Up : Activation
Creating A Warm Up
Test Your Knowledge!
Workout Design: Supersets, Trisets And Circuits
Supersets, Compound Sets, Trisets And Circuits (1:46)
What Are Supersets And Compound Sets?
Opposing Muscle Groups or Antagonist Supersets
WORKOUT: The Chest And Back Superset
Hemisphere Supersets
WORKOUT: The Chest And Legs Superset
Unilateral Supersets
WORKOUT: The Hinge and Pull Unilateral Workout
Activation Compound Sets
WORKOUT: The Back Blaster Sets
WORKOUT: - The Unilateral Glute Workout
Burnout Compound Sets
WORKOUT: The Full-Body Max Out
WORKOUT: 21-15-9 Booty Bonanza
Main + Accessory Compound Sets
WORKOUT: The Booty Builder Compound Set
Lift + Mobility Compound Sets
WORKOUT: The Chest, Shoulders And Tricep Blaster Sets
What Are Trisets?
WORKOUT: Bodyweight Full-Body Triset
What Is Circuit Training?
Full-Body Circuits
WORKOUT: The Full-Body Strength Circuits
Strength + Mobility Circuits
WORKOUT: The Chest And Legs Strength + Mobility Circuits
Hemisphere Activation Circuits
WORKOUT: The Backside Burner Circuit Workout
Supplemental Circuits
WORKOUT: The Killer Squat Workout
Rep Capped Circuits
WORKOUT: The 30s Strength Circuits
WORKOUT: The 40s Rep Capped Core Blast
Sets or Circuits!? The Terminology Overlap
Test Your Knowledge!
Workout Design: Interval Training
What Is Interval Training? (3:03)
The 2:1 Set Up
WORKOUT: The 30/15 Bodyweight Cardio-Core Blast
WORKOUT: The 40/20 Cardio-Core Blast
The 20/20/20 Set Up
WORKOUT: 20/20/20 Battle Ropes Cardio-Core Workout
WORKOUT: The 20/20/20 Stoplight Workout
Using Active Rest
WORKOUT: The Battle Ropes Full-Body Cardio Blast
The 1:1 Set Up
WORKOUT: The 30/30 Full-Body Cardio Blast
"True" HIIT or Power Workouts
WORKOUT: The Anaerobic Blast
Density Intervals
WORKOUT: Isometric Strength Interval Workout
WORKOUT: 2-Tempo Density Interval Workout
Untimed Intervals
WORKOUT: The Descending Distance Sprint Series
WORKOUT: The Rower Ropes Cardio
Endurance Intervals
WORKOUT: The Cardio Endurance Interval Workout
WORKOUT: The Bodyweight 5 Minute Fight Rounds
Test Your Knowledge!
Workout Design: Density Training
What Is Density Training? (2:17)
The "Time To Beat" Set Up
WORKOUT: 10s Rower Relay Workout
WORKOUT: 7s Full-Body Density Set
WORKOUT: The Core-Killer Parfait
Strength Interval Set Up
WORKOUT: 1-Minute Strength Max Out
WORKOUT: The 1-Minute Bodyweight Max Out
Timed Circuits
WORKOUT: The Squat And Press Density Sets
Test Your Knowledge!
Workout Design: Rest-Pause Training Technique
What Is Rest-Pause Training? (2:45)
The 10-7-3-1 Set Up
WORKOUT: Lower Body Posterior 10-7-3-1 Workout
WORKOUT: The 10-7-3-1 Upper Body Blast
The 50s Rep Set Up
WORKOUT: The 50s Full Body Dumbbell Blast
WORKOUT: The 30-20-10 Legs And Back Workout
Test Your Knowledge!
Workout Design: Ladders And Pyramids
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Scientists can now take that "a-ha" moment to go with a method Princeton University researchers developed — and successfully tested — to speed up the chances of an unexpected yet groundbreaking chemical discovery.
The researchers report this month in the journal Science a technique to accomplish "accelerated serendipity" by using robotics to perform more than 1,000 chemical reactions a day with molecules never before combined. In a single day of trials, the Princeton researchers discovered a shortcut for producing pharmaceutical-like compounds that shaves weeks off the traditional process, the researchers report.
The basis of the research was to combine new technology with a unique, rapid-reaction approach that could allow chemists to explore unheard-of and potentially important chemical combinations without devoting years to the pursuit, explained senior researcher and co-author David MacMillan, the James S. McDonnell Distinguished University Professor of Chemistry at Princeton and chair of the department. MacMillan worked with lead author Andrew McNally, a research associate in MacMillan's lab, and Princeton graduate student and co-author Christopher Prier.
"This is a very different way of approaching how we come up with valuable chemical reactions," MacMillan said.
"Our process is designed specifically for serendipity to occur. The molecules that should be combined are those for which the result is unknown," he said. "In our lab, we used this technique to make new findings in a much more routine and rapid fashion, and we show that if you have enough events involved, serendipity won't be rare. In fact, you can enable it to happen on almost a daily basis."
The MacMillan lab's technique does more than just expedite the discovery process — the researchers actually developed a unique framework for creating new materials or finding better ways of producing existing ones, said Stephen Buchwald, a professor of chemistry at the Massachusetts Institute of Technology.
"This is a particularly brilliant approach," said Buchwald, who is familiar with the work but had no role in it.
"Usually, one takes molecules that one thinks will react and tries to figure out the best way to achieve that reaction," he said. "This team took molecules for which there was no obvious reaction between them and looked for 'accidental' reactivity. This approach could be useful for any field that requires new types of matter or a more efficient means of synthesizing known compounds."
Illustrating that principle, the Princeton researchers combined two molecules with no history of reacting to generate the type of chemical functionality found in eight of the world's top 100 pharmaceuticals, MacMillan said. The reaction involved a nitrogen-based molecule known as an amine that has a hydrogen and carbon pair, and a circle of atoms stabilized by their bonds known as an aromatic ring.
The result was a carbon-nitrogen molecule with an aromatic ring, a building block of many amine-based pharmaceuticals, explained MacMillan. This class of drugs mimics natural amine molecules in the body and includes medications such as antihistamines, decongestants and antidepressants. In drug development, chemists "tweak" organic molecules to enhance their ability to bind with and disrupt enzymes in a biological system, which is how pharmaceuticals basically operate, MacMillan said. A molecule with an aromatic ring has increased reactivity and makes the tweaking process much easier, he said, but attaching the aromatic ring is a process in itself that typically involves two to three weeks of successive chemical reactions.
The reaction MacMillan and his team found provides a quick way around that.
"We quickly realized that any pharmaceutical research chemist could immediately take these very simple components and, via a reaction no one had known about, start assembling molecules with an adjacent aromatic ring rapidly," MacMillan said.
"Instead of having to construct these important molecules circuitously using lots of different chemistry over a period of days if not weeks, we can now do it immediately in the space of one chemical reaction in one day."
Buchwald said that the rapid production of this molecule is as surprising as it is significant.
"The way these types of molecules — alpha aryl amines — were produced in this project is highly efficient, and no person could truthfully say that they would have predicted this reaction," Buchwald said. "This group was able to take a reaction that no one knew was possible and make it practical and useful in a very short time. This really speaks to the power of their overall method."
MacMillan conceived of accelerated serendipity after reflecting on his doctoral work at the University of California-Irvine during the 1990s. His work there hinged on two unforeseen yet important reactions that occurred in the span of six years, he said. When envisioning the project reported in Science, MacMillan calculated that if, in a single day, he ran the equivalent of one reaction per day for three years — nearly 1,100 reactions — the odds favored a new discovery, he said.
The Princeton team began running reactions once a day using a high-throughput, automated reaction accelerator in Princeton's Merck Center for Catalysis, combining on a one-to-one ratio molecules with no reported effect on each other.
Central to the process is a technique developed in MacMillan's lab and reported in Science in 2008 to synthesize chemical reactions using a low-power light source, such as a household light bulb. Known as photoredox catalysis, the reaction takes place when inorganic catalysts absorb light particles from the light source then pass an electron onto the organic molecules, which creates, or synthesizes, a new compound.
For the latest work, MacMillan and his team carried out this process on the molecules before each reaction cycle. Because the use of photoredox catalysts in organic-compound synthesis is relatively new — it has been typically used by chemists and in industry for processes such as energy storage and hydrogen production — it has not been as thoroughly explored as the more common method of using catalysts derived from metals such as nickel, gold and copper, MacMillan said. Thus, he said, elements with no history of reacting with each other could possibly produce results under this different approach.
"If one wanted to find new reactions, it would have to be done in a completely new area of chemistry research where the chances of finding something completely unknown are probably higher than continuing in an area that has been studied for the past 50 years," MacMillan said.
The Princeton researchers produced numerous new reactions, but "new" does not necessarily equal interesting or important, MacMillan said. They analyzed and experimented with each new reaction for its potential application, a process that revealed the nitrogen-carbon molecule with the aromatic ring.
An important feature of the Princeton researchers' molecule — like any important discovery — is that its application extends beyond the material itself, MacMillan said. He and his colleagues have begun mining the very process that created the molecule for indications that other novel reactions can be brought about.
"If we found this was one really valuable reaction, we wondered what others exist that we just don't know about," MacMillan said.
"Another very valuable aspect of the molecule we created is that once we understood how it happened, it set us up to design other completely new reactions based upon our understanding of what happened initially," he said. "Now, we're applying similar techniques broadly, finding new reactions continually and determining which ones are important.
"To us that really proved the point of why you want serendipitous findings," MacMillan said. "They present new knowledge, and based upon that new knowledge you can invent."
The research was published Nov. 25 in Science and was supported by a grant from the National Institutes of Health, and gifts from Merck, Amgen, Abbott and Bristol-Myers Squibb.