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We offer a Free quote and UK design service, get in touch today.
We have a selection of play-area safety surfaces in Blackfen DA15 8 that we can create for playgrounds playground safety flooring, including wet pour, rubber mulch, and lawn mats.
Each of the types of play-area surfaces we all install is verified to meet Critical Fall Height ratings for all play equipment in an area to ensure optimum safety for kids.
To find out about the different safety surface specs, please click here http://www.playareasafetysurfaces.co.uk/specification/london/blackfen/
In addition, we make certain the floor products will be porous (allowing water to drain all through the water drainage structure efficiently) to ensure the area will not turn out to be hazardous.
Make sure you fill in the application form, so one of our experts can get in touch with you regarding safe playground safety surfacing, each facility's requirements, and the standards they need to meet.
It is important to make sure that if you have this type of facility installed, that it's conducted by specialists who know what they are doing.
This is to make sure it meets the necessary standards for playgrounds and parks.
we offer free no obligation quotations
GET A QUOTE NOWThere are several playground surface types that you could choose from. We would highly recommend looking into the different safety surfaces, including wet pour, rubber mulch, artificial grass and needlepunch.
Needlepunch surfacing is great for athletics areas. You can learn more about athletics surfacing here http://www.playareasafetysurfaces.co.uk/purpose/athletics/london/blackfen/
It's a good idea to have athletics facilities installed in schools since these can improve Ofsted ratings.
All our surfaces can improve safety in playgrounds since they can be installed in different depths with a shockpad to improve impact absorbing properties.
This can then meet up to certain Critical Fall Heights to guarantee children's safety.
Kids' playground flooring is playground safety surfaces that could be wet pour, made from 2 levels that impact absorbing structure and normally along with a colourful top course.
Rubberised mulch is a more natural-appearing floor; it's manufactured from reusable rubber shreds that make your flooring eco-friendly.
Lawn mats can be fitted in Blackfen above a present playground surfacing so the natural grass will be able to flourish through.
Nearby leisure play areas might help progress young children's education level; patterns and educational games EPDM rubber graphics are often placed to make learning exciting.
Our company offers several coloured graphics for playgrounds and surrounding areas, including hopscotch, number grids, animation character types, and road designs.
The use of wet pour surfacing in your play area or playground is perfect for the safety of those who use it.
It offers the best shock absorption of any safety surface. It's also extremely long-lasting and contains no potentially dangerous materials.
Wet pour surfacing is porous and has great drainage, which is one of the reasons it is so durable.
When it comes to building or building a new playground, surfacing may not be the first thing that comes to mind.
Still, the surfacing of any playground is crucial, and it must be built of robust, shock-absorbing materials.
The surface must first and foremost be hard and stable to guarantee that it is not excessively stiff and will not damage a fallen youngster in the use zone.
Selecting the appropriate playground surfacing can help you lower the risk of injuries, putting you one step closer to creating a safer play area.
When it comes to selecting the ideal safety surfacing, a variety of aspects must be considered, including affordability, fall attenuation, accessibility, and more.
Our playground safety surfacing alternatives can help you figure out what's best for your kids.
Our own local pros closest to you can also carry out upkeep servicing and testing to keep your playground surface in optimum state and be sure it's stable.
This is advisable because a clean-up strategy allows you to prevent being forced to carry out major maintenance to your exterior.
The cost of servicing in Blackfen DA15 8 and repair services will vary because of the safety surface kind and variety or repairs and preservation necessary.
When your wet pour safety surfacing has got debris, unwanted weeds, or other contaminants onto it, you must take it off as fast as possible.
This will be relevant considering that contamination can obstruct a drainage structure.
To speak to our specialists surfacing installers, make sure to fill in the contact form provided.
Sometimes offering the kids' playground flooring near you, a delicate power rinse should be sufficient to avoid contamination.
Rubberised mulch can also be cleaned utilising a light power cleanse as well as brushing. It's possible to want to top up your rubber as time goes on.
If you require more details on the play surface maintenance, please click here http://www.playareasafetysurfaces.co.uk/maintenance/london/blackfen/
Reactive servicing is essential in the event your flooring does become damaged. If you put it off for too long, your renovations can get more expensive.
Gum marks and other blemishes could very well be dealt with easily once they are managed as quick as possible.
If a part of ones glued rubber mulch becomes loose, it may be messed with, resulting in problems that would worsen; if this happens, a rubber mulch repair will be essential.
Lawn mats may become a falling threat if they've become loosened and elevated up. This means you will need to restore this quickly.
Cracks around a play area EPDM rubber surfacing may occur eventually. If there are minor repairs such as this, you can actually buy a mend set and then perform the restorations by yourself.
It's critical to examine the numerous possibilities and consult with industry professionals before deciding on the best surface for your new playground.
Your playground's needs and requirements are likely to be unique, and a playground surfacing expert can assist you in determining which surfacing type is appropriate for the specific site and playground users.
In other circumstances, a single surface type may not be suitable for all of your needs or the various forms of play you want for your project.
In that scenario, you might want to think about using a variety of surface materials in your project.
We have the proper alternatives for you whether you need a playground surface for a school, park, hospitality center, community center, or early childcare center.
As we are specialists in the safety surfacing industry, we have carried out various projects all across the UK, which has been to a high standard and different design specifications.
If you've got any questions about our play-area surfaces and the services we can provide, please feel free to contact us.
We would be happy to talk you through our playground safety surfaces in Blackfen DA15 8 and offer you a competitive quote for the work.


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JetBlue Airways is a noteworthy carrier in Dubai, United Arab Emirates. In the said city, it gives effect to its operations from JetBlue Airways Dubai Airport Terminal. The airport's terminal gets efficiently used. From here, multiple flights are seen in operation on a daily basis. To both international and domestic destinations, millions of flyers are assisted by the carrier to complete their journeys.
About JetBlue Airways Terminal DXB
Various terminals can be found at the airport. They have been enriched with several facilities for passengers. With every JetBlue Airways DXB Terminal, you can benefit from the developments available. Whether you want to sit or relax, you can find ample space and seating options available. For requirements such as lounges and shops as well, the terminals are equipped.
JetBlue Airways Dubai Airport (DXB)
DXB or Dubai Airport is recognized for its expansive space. It is because of this that DXB can account for various facilities of the airline. The availability of the same ensures that countless travelers are able to comfortably fly, as and when required, with this carrier.
Flight Reservations
At this airport's terminal, the airline has set up counters for making reservations. Passengers often approach the counters to book tickets for various routes. Regardless of the number of passengers approaching, JetBlue Airways Terminal Dubai Airport ensures that professional services are ensured to all.
Counter for Flight Management
As you decide to fly from one city or country to another, the DXB Airport terminal becomes significant to manage your flights. Through this terminal, the air operator gives the facility of making modifications to the bookings. They can be in the form of changes relating to the date, time, schedule, location, class type, and the like. The counters available at the terminal will be of help to receive information regarding your concerns.
Cancel Your Bookings
The airline believes that travelers can require canceling their tickets at any point in time. When situations suddenly emerge, it goes a step further to aid the travelers. Thus, the option to cancel bookings is provided. At the JetBlue Airways DXB Terminal, the knowledge of complete cancellation procedures is available. The staff can also initiate revocations on a traveler's behalf when greater guidance is required.
Seat Upgradation
Seat upgrades can see to it that your traveling experience is better than expected. With this facility at the terminal, you can enhance your time spent onboard. Better services, seating, etc., can be availed of. At the counters of this terminal at the airport, you can find proper directions to upgrade your seat. For changing your ticket class as well, this option can be preferred.
Manage Your Baggage
When you are carrying luggage with you, reserving allowance is vital. To remove any complexities related to this, the carrier ensures the management of baggage facilities. In case you have already booked this allowance but need to alter it, you can come to the Terminal. You can remove the number of bags or extend the allowance as needed.
Curbside Check-in
This carrier hopes to make your flying experience as comfortable as possible. In order to do so, it gives the curbside check-in option. It is a time-saving facility to board your flight fast. Other processes such as accessing your boarding pass, checking in your luggage, etc., can also require less time. To understand further about the JetBlue Airways curbside check-in facility, the airport staff will assist you.
Lost and Found Service
While traveling, flyers may often leave certain possessions behind. Understanding how valuable or important every item can be, this carrier has made a lost and found service. It unites flyers with their bags or items as quickly as possible. Whether the bags are left at the airport or onboard, the JetBlue Airways Lost and Found Department makes every effort to find them back.
How to Obtain Your Boarding Pass at JetBlue Airways Airlines DXB Airport Terminal?
It must be known that without a boarding pass, catching your flight cannot be successful. Therefore, you should be aware of how to access this document for a problem-free onboarding process. At the airport terminal, JetBlue Airways lets you print your passes via kiosks. To receive additional information for using kiosks, the counters functioning here will be useful.
Reasons to Contact JetBlue Airways at Dubai Airport
When you are flying with this airline, you can receive exceptional services throughout your journey. At DXB Airport Terminal, you will be properly assisted in the ways you require. After boarding your flight, every facility that can enhance your experience will be given, depending on the class fare purchased. You can contact the airline in this regard.
Using the JetBlue Airways DXB address or phone number, you can reach the terminal of the airport. Following this, you can find numerous facilities available.
- Travelers can ask for entertainment options available on the flight.
- For seat and space availability, this airline will give you the best options.
- To learn about frequent flyer programs or any similar facilities, your doubts will be handled on priority as you contact this airline.
- For any support pertaining to your medical condition, you may ask the airline about the arrangements available.
Frequently Asked Questions (FAQs)
It is usual for any customer to be struck by doubts. The customers can find help through the frequently asked questions and their answers.
This airline is available at Terminal 3 of DXB Airport. This is functional for both domestic and international travelers.
Domestic arrivals can be observed at Terminal 3 of this airport. For international arrivals, this airline's passengers can refer to Terminal 3. For more accurate information, consider connecting with the air operator.
When the departure relates to a domestic location, Terminal 3 is to be used. The same JetBlue Airways Terminal Dubai Airport remains available for departing to international locations. All the facilities required for smooth departures are given here.
Usually, 3.00 A.M. onwards, the ticket counters of most carriers open at the airport. Thus, you are likely to find this airline's counters following the same schedule. Till 9.00 P.M., they can be available.

subset: commoncrawl


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About Us
Here at heart shirt we are obsessed with creating things that YOU are obsessed with. We're the perfect place to find apparel and merch based on your favorite heart shirt. But we're not just like every other store out there.
Our commitment to quality and attention to detail is unmatched. We don't take shortcuts and that's what makes us the right brand for you. We are the cool, high-quality retailer of clothes and accessories. We provide the best customer service experience on the market.
Start the day with a burst of color or end the night with an explosion of happiness. Our clothes and home decor will help bring your mood to a better place. Bring a little life to your home and wardrobe today!
Happy Shopping!


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The following graph plots the year-to-date performance of the stock for 1996 compared to the probability calculated by a random walk model.
Initial Value*: $5.5
Hist. Volatility: 1.3%
Annual Drift: 7%
Final Value*: $6.3
Percentile: 65%
The high to date and low to date prices of the stock plotted against a random walk model for 1996 (what's this?).
© 2005, 2016, The Research Foundation of State University of New York, http://www.textbiz.org


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GOLDfren began manufacturing sintered disc brake pads for a wide range of off-road and road motorcycles in 1991, nearly three decades on from their first motorcycle brake pads GOLDfren has become one of the largest aftermarket manufacturers in the motorcycle brake disc pad industry. Their development of next-generation products has kept them at the technological forefront of Sintered Friction Braking providing you with confidence in the performance, durability and reliability of your brakes.
S3 Series:
The S3 sintered compound is optimal in dry and wet conditions for road & off-road motorcycles. For the road application, S3 pads are suitable for both the front and rear brake while on off-road applications the S3 is only recommended for the front brake. The S3 series is designed for low abrasive interaction with the rotor and quieter braking due to the ceramic composite material. It has an HH friction rating and performs better at higher temperatures than the AD compound. Friction materials contain metal-ceramic with a bronze-graphite and non-metallic friction additives are spread evenly on the base fine bronze body to achieve optimal friction properties.
- Very high static friction coefficient
- Minimal difference between wet and dry braking performance
- Good abrasive resistance
- Low abrasive interaction with the brake rotor material
- Longer life compared to organic and Kevlar composite materials
- For riders who demand a bit more than average from their bikes
- Recommended on both front and rear brakes (road application)
- Can also be used on the front brakes of off-road bikes and ATVs
- Works well on both dry and wet conditions
Operating Parameters:
- Specific pressure: 3.0 Mpa
- Sliding speed: 45 m/s
- Constant maximum temp: 450°C
- Short time maximum temp: 800°C
- Counter-surfaces: steel disks
What is a sintered brake pad?
GOLDfren only manufacturers sintered brake pads that contain metal-ceramic and ceramic-carbon friction materials, these materials allow for less brake dust and a quieter braking experience. Sintered brake pads are made by fusing together metallic particles under high temperature and pressure which enhances friction properties and pad life, resulting in longer life and stronger braking. Sintered brake pads experience no brake fade when operating at high temperatures and in wet conditions. They also last up to 5 times longer than organic pads and provide additional braking strength. All materials used are environmentally friendly and do not contain any lead, asbestos, fibreglass or formaldehyde.
Reminder: one set of brake pads services one brake disc, if you are servicing multiple discs you will need multiple sets of brake pads.


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New Hampshire; Amendment No. 1 to Notice of a Major Disaster Declaration, 56776-56777 [2011-23496]
Download as PDFAgencies
[Federal Register Volume 76, Number 178 (Wednesday, September 14, 2011)] [Notices] [Pages 56776-56777] From the Federal Register Online via the Government Printing Office [www.gpo.gov] [FR Doc No: 2011-23496] ----------------------------------------------------------------------- DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-4026-DR; Docket ID FEMA-2011-0001] New Hampshire; Amendment No. 1 to Notice of a Major Disaster Declaration AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. ----------------------------------------------------------------------- SUMMARY: This notice amends the notice of a major disaster declaration for the State of New Hampshire (FEMA-4026-DR), dated September 3, 2011, and related determinations. DATES: Effective Date: September 7, 2011. FOR FURTHER INFORMATION CONTACT: Peggy Miller, Office of Response and Recovery, Federal Emergency [[Page 56777]] Management Agency, 500 C Street, SW., Washington, DC 20472, (202) 646- 3886. SUPPLEMENTARY INFORMATION: The notice of a major disaster declaration for the State of New Hampshire is hereby amended to include the Individual Assistance program in the following areas among those areas determined to have been adversely affected by the event declared a major disaster by the President in his declaration of September 2, 2011. Carroll and Grafton Counties for Individual Assistance (already designated for Public Assistance, including direct federal assistance). (The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be used for reporting and drawing funds: 97.030, Community Disaster Loans; 97.031, Cora Brown Fund; 97.032, Crisis Counseling; 97.033, Disaster Legal Services; 97.034, Disaster Unemployment Assistance (DUA); 97.046, Fire Management Assistance Grant; 97.048, Disaster Housing Assistance to Individuals and Households in Presidentially Declared Disaster Areas; 97.049, Presidentially Declared Disaster Assistance--Disaster Housing Operations for Individuals and Households; 97.050, Presidentially Declared Disaster Assistance to Individuals and Households--Other Needs; 97.036, Disaster Grants--Public Assistance (Presidentially Declared Disasters); 97.039, Hazard Mitigation Grant.) W. Craig Fugate, Administrator, Federal Emergency Management Agency. [FR Doc. 2011-23496 Filed 9-13-11; 8:45 am] BILLING CODE 9111-23-P
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Wisdom Teeth Removal
Ask Walla Walla Dental Care if our services are right for you
Make an AppointmentMost people need their wisdom teeth removed because there isn't enough space for them to come in properly. They tend to come in at an angle or they don't fully emerge. Third molars (the wisdom teeth) routinely damage the teeth right next door, called second molars. When wisdom teeth come in sideways like this, it throws off your bite, creates an area where food gets caught, decays both of the teeth and can even cause a painful infection.
Common problems associated with wisdom teeth misalignment include:
- Painful, swollen gums
- Infection
- Crowded or damaged surrounding teeth
- Possible damaged nerves and jawbone
Although it's normal for patients to fear the wisdom teeth removal process, the dental team at Walla Walla Dental Care will provide the safest, most comfortable extraction procedure possible.
The extraction procedure:
- Local, sedation or general anesthesia is administered
- An incision is made in the gum tissue
- The bone that blocks access to the tooth root is removed
- The wisdom tooth is removed
- The site of the removed tooth is cleaned
- The wound is stiched close to promote healing, though this isn't always necessary
- Gauze is placed over the extraction site to control bleeding and to help a blood clot form
We can evaluate the state of your teeth and advise you on the most convenient and effective schedule for successful treatment. Call your Walla Walla dentist at 509-525-4833 today to schedule a consultation.


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Garden Frog
"Garden Frog" is shown in our Linen Formula
We have combined artisanal craftsmanship with researched formulas to provide a bar of soap that is both beautiful and beneficial for your skin. Packed with an abundance of antioxidants, silk proteins, natural botanicals, and mineral-rich clay, our handmade soaps are created for pure luxury.
Scented exclusively with essential oils. Learn about each formulation, below:
Each Hippy Sister face & body soap is hand-crafted and made to order, which can lead to color variations. Our soaps take between 1-5 business days to ship, but we think they are worth the wait! Each soap in our Luxury and Gift Set Collections are packed in our custom window boxes. Soaps ordered as gifts are given some special touches, including organza ribbon, a hand-written note, and coordinating shipping boxes.
Our Formulations
Deep Rose: Red Reef Clay, White Kaolin Clay, Silk Powder, Aloe Vera Powder, Colloidal Oatmeal.
Dusty Rose: Rose Kaolin Clay, Silk Powder, Aloe Vera Powder, Colloidal Oatmeal.
Ebony: Dead Sea Clay, Silk Powder, Activated Charcoal, Green Tea Extract, Olive Leaf Extract, Pomegranate Extract.
Ivory: White Kaolin Clay, Silk Powder, Aloe Vera Powder, Colloidal Oatmeal.
Jade: Green Clay, Silk Powder, Organic Seaweed, Organic Spirulina, Organic Chlorella.
Linen: Glacial Clay, Silk Powder, Burdock Root Extract, Cucumber Extract, Sea Buckthorn Extract.
Exfoliating Buff / *Charcoal: Sandalwood Powder, Frankincense Powder, Pumice, *Activated Charcoal.
Included Ingredients in all Formulations of Certified Organic ~ Saponified: Unrefined Shea Butter, Sunflower Oil, Virgin Coconut Oil, Extra Virgin Olive Oil, Raw Cacao Butter, Castor Seed Oil, Golden Jojoba.
All soaps are colored naturally with spa quality clay, botanicals, and enhanced with mineral mica.
Each Formulation has a unique scent, fragranced using a special blend of some of the following Therapeutic blend of Essential Oils: Bergamot, Black Pepper, Cedarwood, Eucalyptus, Ginger, Lavender, Lemongrass, Litsea Cubeba, Patchouli, Peppermint, Rosemary, Spearmint, Sweet Orange.


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Cat. # | Size | Qty. | Price |
13820T | 20 µl |
13820S | 100 µl |
SENSITIVITY | Endogenous |
MW (kDa) | 60 |
Source/Isotype | Rabbit IgG |
Product Information
Application | Dilution |
Western Blotting | 1:1000 |
Immunoprecipitation | 1:50 |
Immunofluorescence (Immunocytochemistry) | 1:400 - 1:1600 |
Flow Cytometry (Fixed/Permeabilized) | 1:200 - 1:800 |
Chromatin IP | 1:50 |
For western blots, incubate membrane with diluted primary antibody in 5% w/v BSA, 1X TBS, 0.1% Tween® 20 at 4°C with gentle shaking, overnight.
NOTE: Please refer to primary antibody product webpage for recommended antibody dilution.
From sample preparation to detection, the reagents you need for your Western Blot are now in one convenient kit: #12957 Western Blotting Application Solutions Kit
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
Load 20 µl onto SDS-PAGE gel (10 cm x 10 cm).
NOTE: Loading of prestained molecular weight markers (#59329, 10 µl/lane) to verify electrotransfer and biotinylated protein ladder (#7727, 10 µl/lane) to determine molecular weights are recommended.
NOTE: Volumes are for 10 cm x 10 cm (100 cm2) of membrane; for different sized membranes, adjust volumes accordingly.
* Avoid repeated exposure to skin.
posted June 2005
revised June 2020
Protocol Id: 10
This protocol is intended for immunoprecipitation of native proteins utilizing Protein A agarose beads for analysis by western immunoblot or kinase activity.
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
10X Cell Lysis Buffer: (#9803) To prepare 10 ml of 1X cell lysis buffer, add 1 ml cell lysis buffer to 9 ml dH2O, mix.
NOTE: Add 1 mM PMSF (#8553) immediately prior to use.
IMPORTANT: Appropriate isotype controls are highly recommended in order to show specific binding in your primary antibody immunoprecipitation. Use Normal Rabbit IgG #2729 for rabbit polyclonal primary antibodies, Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 for rabbit monoclonal primary antibodies, Mouse (G3A1) mAb IgG1 Isotype Control #5415 for mouse monoclonal IgG1 primary antibodies, Mouse (E5Y6Q) mAb IgG2a Isotype Control #61656 for mouse monoclonal IgG2a primary antibodies, Mouse (E7Q5L) mAb IgG2b Isotype Control #53484 for mouse monoclonal IgG2b primary antibodies, and Mouse (E1D5H) mAb IgG3 Isotype Control #37988 for mouse monoclonal IgG3 primary antibodies. Isotype controls should be concentration matched and run alongside the primary antibody samples.
Proceed to one of the following specific set of steps.
NOTE: When using primary antibodies produced in rabbit to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Mouse Anti-Rabbit IgG (Light-Chain Specific) (D4W3E) mAb (#45262) or Mouse Anti-Rabbit IgG (Conformation Specific) (L27A9) mAb (#3678) (or HRP conjugate #5127) as a secondary antibody to minimize interference produced by denatured rabbit heavy chain. For proteins with a molecular weight in the range of 25 kDa, Mouse Anti-Rabbit IgG (Conformation Specific) (L27A9) mAb (#3678) (or HRP conjugate #5127) is recommended to minimize interference produced by denatured mouse light chain.
When using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain Specific) (D3V2A) mAb (HRP Conjugate) (#58802) as a secondary antibody to minimize interference produced by denatured mouse heavy chain.
posted December 2008
revised October 2021
Protocol Id: 409
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalently purified water.
Recommended Fluorochrome-conjugated Anti-Rabbit secondary antibodies:
NOTE: Cells should be grown, treated, fixed and stained directly in multiwell plates, chamber slides or on coverslips.
NOTE: All subsequent incubations should be carried out at room temperature unless otherwise noted in a humid light-tight box or covered dish/plate to prevent drying and fluorochrome fading.
posted November 2006
revised December 2010
Protocol Id: 32
All reagents required for this protocol may be efficiently purchased together in our Intracellular Flow Cytometry Kit (Methanol) #13593, or individually using the catalog numbers listed below.
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
NOTE: When including fluorescent cellular dyes in your experiment (including viability dyes, DNA dyes, etc.), please refer to the dye product page for the recommended protocol. Visit www.cellsignal.com for a full listing of cellular dyes validated for use in flow cytometry.
NOTE: Adherent cells or tissue should be dissociated and in single-cell suspension prior to fixation.
NOTE: Optimal centrifugation conditions will vary depending upon cell type and reagent volume. Generally, 150-300g for 1-5 minutes will be sufficient to pellet the cells.
NOTE: If using whole blood, lyse red blood cells and wash by centrifugation prior to fixation.
NOTE: Antibodies targeting CD markers or other extracellular proteins may be added prior to fixation if the epitope is disrupted by formaldehyde and/or methanol. The antibodies will remain bound to the target of interest during the fixation and permeabilization process. However, note that some fluorophores (including PE and APC) are damaged by methanol and thus should not be added prior to permeabilization. Conduct a small-scale experiment if you are unsure.
NOTE: Count cells using a hemocytometer or alternative method.
posted July 2009
revised June 2020
Protocol Id: 404
Human, Mouse, Rat
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser463/465 of human SMAD1 and SMAD5 protein.
Bone morphogenetic proteins (BMPs) constitute a large family of signaling molecules that regulate a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation, and apoptosis (1,2). BMP receptors are members of the TGF-β superfamily of Ser/Thr kinase receptors. Ligand binding induces multimerization, autophosphorylation, and activation of these receptors (3-5). They subsequently phosphorylate SMAD1 at Ser463 and Ser465 in the carboxy-terminal motif SSXS, as well as SMAD5 and SMAD9 (SMAD8) at their corresponding sites. These phosphorylated SMADs dimerize with the coactivating SMAD4 and translocate to the nucleus, where they regulate the transcription of target genes (5). MAP kinases and CDKs 8 and 9 are also reported to phosphorylate residues in the linker region of SMAD1, including Ser206. Phosphorylation of SMAD1 at Ser206 recruits Smurf1 to the linker region and leads to the degradation of SMAD1 (6). Phosphorylation at this site also promotes SMAD1 transcriptional activity by recruiting YAP to the linker region (7).
Explore pathways related to this product.
Except as otherwise expressly agreed in a writing signed by a legally authorized representative of CST, the following terms apply to Products provided by CST, its affiliates or its distributors. Any Customer's terms and conditions that are in addition to, or different from, those contained herein, unless separately accepted in writing by a legally authorized representative of CST, are rejected and are of no force or effect.
Products are labeled with For Research Use Only or a similar labeling statement and have not been approved, cleared, or licensed by the FDA or other regulatory foreign or domestic entity, for any purpose. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, prophylactic or therapeutic purposes, or any purchase of Product for resale (alone or as a component) or other commercial purpose, requires a separate license from CST. Customer shall (a) not sell, license, loan, donate or otherwise transfer or make available any Product to any third party, whether alone or in combination with other materials, or use the Products to manufacture any commercial products, (b) not copy, modify, reverse engineer, decompile, disassemble or otherwise attempt to discover the underlying structure or technology of the Products, or use the Products for the purpose of developing any products or services that would compete with CST products or services, (c) not alter or remove from the Products any trademarks, trade names, logos, patent or copyright notices or markings, (d) use the Products solely in accordance with CST Product Terms of Sale and any applicable documentation, and (e) comply with any license, terms of service or similar agreement with respect to any third party products or services used by Customer in connection with the Products.


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Information on this page was last updated on 15 Nov 2021
We've made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.


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Acceptance of Terms Through Use:
Welcome to gograysharbor.coma website operated by Jodesha Broadcasting (hereinafter "Go Grays Harbor"). Please read the following terms and conditions carefully, as they govern your use of the Go Grays Harbor website (hereinafter the "Site"). Your use of the Site constitutes your acceptance without modification of all of the terms, conditions, and notices contained herein. We offer the Site to you conditioned on your acceptance of these Terms of Use. In consideration of your agreement to these Terms of Use and for other valuable consideration, we grant to you a limited, non-exclusive, revocable and non-transferable license (as referenced below) to access and use the Site. We reserve all rights not expressly granted in this Agreement.
We reserve the right to make modifications, improvements, deletions, or amendments to the Site at any time we deem appropriate. Any and all relevant portions of this Agreement will apply automatically to all modifications, improvements, deletions, and/or amendments as they appear.
In addition, we reserve the right at any time to modify the terms and conditions of this Agreement, or any part thereof, or to impose new conditions on the Agreement. Except as otherwise stated herein, any modification to this Agreement shall be effective ten (10) days after it initially is posted on the Site. Your use of the Site after any such change will be conclusively deemed acceptance of such change.
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Call Us (801)489-5621
Text Us: (877)619-5621
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We work closely on this matter with Popetech Accessibility which is an Enterprise-Level Web Accessibility Evaluation System, based on WAVE that provides site-wide monitoring and reporting of accessibility over time.


text:
This website was created using ShutterForge.com photography website hosting.
Theme design by Scott Smith, http://scottsmith.photos.
This site may use floral images from AngieMakes.com.
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This site may use Pexels background images used on Creative Commons License, available here.
This site may use images from Pixabay under Creative Commons License, available here.


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Saying that "recent events" have raised questions, but that "there is no reason that the legitimate issues raised by many about this bill cannot be resolved," Senate Majority Leader Harry Reid has announced that there won't be a vote in his chamber next Tuesday on the Protect IP Act (PIPA).
That's the Senate's version of controversial legislation that supporters say would cut down on Internet piracy — but that opponents say would amount to censorship.
Wednesday, as we and many others wrote, Wikipedia and some other Web giants who oppose such legislation focused attention on it by "going black." And as NPR's David Welna reported, Wikipedia and the sites urged people "to complain to their lawmakers about the proposed anti-piracy legislation" and got a big response. "Heavy traffic caused more than half the official websites of senators to crash" on Wednesday, David found.
He also pointed out that "nearly half the Senate bill's 40 sponsors are Republicans, but many of them have withdrawn their support in the past few days." So, David said, if the legislation was to get through the Senate, it might first have to be altered.
Reid's decision now gives some time for such alterations. He gave no specific time for a vote, but said he's confident a compromise can be reached "in the coming weeks."
Copyright 2020 NPR. To see more, visit https://www.npr.org.


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Most of our HCC Library Searches in one place.
Discover books, media, and articles with a single search
Find databases of articles, eBooks, and streaming media here.
Find high quality open access (free to use) databases by program/subject or format.
FInd books, media, and journal titles, but no articles.
Search for licensed (HCC only) or open access eBooks or browse eBook collections.
Whether you are a student using library resources to complete a paper, faculty creating digital handouts for a class this guide is for you.
The best user-friendly resources gathered by HCC librarians to help you with your research and assignments
Find and use resources in other libraries.
Learn to find and cite your sources, how to get started with your writing assignments, and more.
is the HCC Library's comprehensive guide to completing your research assignment.
guides you through scientific research.
These resources will help you cite your sources correctly and avoid plagiarism.
Use these sources for background information on your topic and for quick facts and statistics.
Use these resources to understand plagiarism and how to avoid it.
Hone your writing skills here. We have provided sample papers for comparison.
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Find information about the HCC Libraries here.
Find librarian contact information, CVs, and more here.
When and where to visit the libraries, along with contact and staffing information.
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How many books can you check out? How are the libraries organized? Find out here.
Suggest a purchase, or let us know how we're doing. We want to read from you!
Visualize the scope and use of our resources and services.
Watch online: We love libraries!
Get personal assistance from an HCC librarian or find answers in our Frequently Asked Questions.
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Librarians use these links, but some of them are useful for HCC students and faculty, too.
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The best way to locate library resources is to use the HCC Library Homepage.
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text: At C V Hardwoodflooring we specialize in Installation, sanding (using a dustless system) and refinishing of all types of woods for your home or office. This includes all flooring, stairs and any other items such as baseboards etc.. We discuss with our clients in detail the style and look they are trying to obtain and we will make it happen. C V Hardwoodflooring also specializes in the art of exceptional detail when it comes to unique designs and hardwoods. Feel Free to call us today for your complimentary consultation. We are proud to serve Chicago land and all surrounding suburbs, including Chicago Heights, IL . We can help create your ideal floors by applying extensive detail to design, style, and soundproofing. Whether you want hardwood floor for a room or the entire house, we will surpass the quality expectations and ensure to bring satisfaction to you as our clients.


text: New Topic You're not currently permitted to view this content. Please log-in or register in order to view the page.Log inRegister Username Password Lost password? Username Email First Name Last Name Password Password again Are you a human? No Yes Please make sure all required fields are filled out. Post Views: 120


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David Plowden's Iowa
During his 50-year career, David Plowden sought to capture the once commonplace but now rapidly vanishing scenes of small-town and rural America. David Plowden's Photographs showcases Plowden's photographs of local Iowans and communities during a 20-year period.
Comparable to the photographers of the Works Progress Administration (WPA) of the New Deal era, Plowden's photographs are a window in time. His photographs often focus on the slow decline of aging industries and communities at a particular moment.
In his photograph Van's Clothing, Victor, Iowa (1986), the storefront evokes a sense of nostalgia. The recessed, glass door displaying the gloves on a string draw the eye to the strong contrast of light and dark. Yet this place is not set in the distant past. Details like the replaced door handle suggest modernity. The reflection of the brick storefront opposite Van's Clothing in Victor foreshadows the clothing store's own fate–empty and closed.
Unlike Van's Clothing, the photograph Grain Elevators, Manson, Iowa (2004), implies prosperity instead of slow decline in rural America. The agricultural industry behemoths in Grain Elevators become "indigenous skyscrapers." The large, industrial buildings are the tent poles of local Midwestern towns and farming communities. Without them, a surrounding community inevitably would decline. Here the stark white buildings showcase the latest technological advancements in agricultural production and transportation against an overcast sky. Old industries, farming and the railroad continue to support and define rural life.
In this exhibition, Plowden's photographs entice the viewer to get a "sense of" what life was, or still is, like in rural Iowa. He does not define Iowa or its inhabitants for his audience; instead, Plowden's photographs rely on the viewer's interpretation.
This exhibition is a collaboration between the Humanities Iowa, the Figge and other institutions. Learn more about the exhibition at a website sponsored by Humanities Iowa.
This exhibition will be on view May 12-August 26, 2012.
The exhibition catalogue for David Plowden's Iowa, featuring an introduction by Figge Associate Curator, Rima Girnius, is for sale in the Museum Store
David Plowden, Grain Elevators Manson, Iowa, 2004, archival ink jet print, collection of Humanities Iowa; © 2004 David Plowden


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It's time for you to get the care you need, and when you're in our hands, you can rest assured that you're getting the best there is. We strive every day to be the skilled nursing facility of choice in our community, so we make sure that each day you spend with us is filled with the caliber of service that will make your stay comfortable, safe and therapeutic. The entire staff will know you by name, and each day when we greet you, we'll ask you how you are, and whether there is anything we can do for you. We never forget that you're our valued guest, and the reason we're here! And remember, if you have a special request, please don't hesitate to ask. That's why we're here – for you!
Your Path for Success
Family Involvement Leads To Patient Success


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H19-366 Exam Pack: Prepare Your Huawei Certified Pre-sales Specialist IP (HCS-Pre-Sale-IP) Exam with three easy to use formats.
Huawei H19-366 Exam Questions Bundle Pack Includes:
Number of Questions: 437 Last Updated: Jul 21, 2024
Number of Questions: 437 Last Updated: Jul 21, 2024
If you are worried about the preparation of your H19-366 exam, so stop distressing about it because you have reached the reliable source of your success. Passitcertify.com is the ultimate solution to your all Huawei Certified Pre-sales Specialist IP (HCS-Pre-Sale-IP) related problem. It provides you with a platform that enables you to clear your H19-366 exam. PassITcertify provides you H19-366 exam questions that are reliable and offer you a gateway to your destination. The Huawei Certified Pre-sales Specialist IP (HCS-Pre-Sale-IP) exam material is available in three easy formats; PDF, Practice Test (web-based) and Desktop Practice Test Software. It carries all subjects related question answers and with the best possible instructions. One of the most influential features of Passitcertify is its practising software. You may attempt to exercise questions continually. In fact, you can also track your progress, as the practice test software will keep on monitoring your progress so you can keep a check-in which area you need to work hard. H19-366 exam questions have been designed by the subject matter experts after consultation with proposed study material of vendor and recruiter needs.
Huawei H19-366 Related Certifications
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The H19-366 exam practice test's user-friendly interface is made to uproot potential problems. Once you will try the demo of H19-366 exam questions, you will be well-acquainted with the software and its related features. Also, the H19-366 exam comes with various self-assessment features like a timed exam, randomize questions, and multiple questions types, test history, and score, etc. This means, it enables you to customize the question type and you may practice random questions to enhance your skills and expertise. You may keep attempting the same questions multiple times also.
Multiple companies are offering H19-366 exam material in the market, so we totally understand your inquisitiveness that whom to trust. For your convenience, Passitcertify gives you a chance to try a free demo of Microsoft H19-366 exam questions, which means you can buy the product once you are satisfied with the features and you think it can actually help you to pass your certification exam.
Updated Exam Questions


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As we reach middle age, particularly after age 40, it is common to start to experience difficulty with reading and performing other tasks that require near vision. This is because with age, the lens of our eye becomes increasingly inflexible, making it harder to focus on close objects. Unlike a true eye disease, this condition is so common, it eventually happens to almost everyone who reaches old age to some extent. It's called presbyopia.
To avoid eyestrain, people with untreated presbyopia tend to hold books, magazines, newspapers, and menus at arm's length in order to focus properly. Trying to performing tasks at close range can sometimes cause headaches, eye strain or fatigue in individuals who have developed this condition.
Causes of Presbyopia
During our youth, the lens of our eye and the muscles that control it are flexible and soft, allowing us to focus on close objects and shift focus from close to distant objects without difficulty. As the eye ages however, both the lens and the muscle fibers begin to harden, making near vision a greater challenge.
Presbyopia is a natural result of the aging process and not much can be done to prevent it. Its onset has nothing to do with whether you already have another vision impairment such as nearsightedness, farsightedness or astigmatism. Everyone will notice some degree of loss of near vision focusing power as they age, although for some it will be more significant than others.
Symptoms and Signs of Presbyopia
Presbyopia is characterized by:
- Difficulty focusing on small print
- Blurred near vision
- Experiencing eyestrain, fatigue or headaches when doing close work or reading
- Needing to hold reading material or small objects at a distance to focus properly
- Requiring brighter lighting when focusing on near objects
Presbyopia can be diagnosed in a comprehensive eye exam.
Treatment for Presbyopia
There are a number of options available for treating presbyopia including corrective eyewear, contact lenses or surgery.
Reading glasses or "readers" are basically magnifying glasses that are worn when reading or doing close work that allow you focus on close objects.
Eyeglasses with bifocal or multifocal lenses such as progressive addition lenses or PALs are a common solution for those with presbyopia that also have refractive error (nearsightedness, farsightedness or astigmatism). Bifocals have lenses with two lens prescriptions; one area (usually the upper portion) for distance vision and the second area for near vision. Progressive addition lenses or PALs similarly provide lens power for both near and distance vision but rather than being divided into two hemispheres, they are made with a gradual transition of lens powers for viewing at different distances. Many individuals prefer PALs because unlike bifocals, they do not have a visible division line on the lens.
Bifocal and Multifocal Contact Lenses
For individuals that prefer contact lenses to glasses, bifocal and multifocal lenses are also available in contact lenses in both soft and Rigid Gas Permeable (RGP) varieties.
Multifocal contact lenses give you added freedom over glasses and they allow you to be able to view any direction – up, down and to the sides – with similar vision. People wearing progressive lenses in glasses on the other hand have to look over their glasses if they want to view upwards or into the distance.
Another option for those who prefer contact lenses is monovision. Monovision splits your distance and near vision between your eyes, using your dominant eye for distance vision and your non-dominant eye for near vision. Typically you will use single vision lenses in each eye however sometimes the dominant eye will use a single vision lens while a multifocal lens will be used in the other eye for intermediate and near vision. This is called modified monovision. Your eye doctor will perform a test to determine which type of lens is best suited for each eye and optimal vision.
There are surgical procedures also available for treatment of presbyopia including monovision LASIK eye surgery, conductive keratoplasty (CK), corneal inlays or onlays or a refractive lens exchange (RLE) which replaces the hardened lens in the eye with an intraocular lens (IOL) similar to cataract surgery.
Since it affects so much of the older population, much research and development is going into creating more and better options for presbyopes. Speak to your eye doctor about the options that will work best for you.


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As President Obama and Mitt Romney enter tonight's debate, here are a few lessons, compliments of others who have taken to the podium:
Laugh At Yourself
The second 1984 presidential debate showcased President Ronald Reagan's ability to gently poke fun at his critics and himself. Asked if his age, then 73, could prevent him from fulfilling the duties of his office, Reagan joked: "I will not make age an issue of this campaign. I am not going to exploit, for political purposes, my opponent's youth and inexperience." Even Democratic challenger Walter Mondale, 55, laughed.
Sen. John McCain got a big laugh in the Republican primary debate in 2007 with a joke about Woodstock — while still managing to score points with a reference to his military service and time as a prisoner of war. "I'm sure it was a cultural and pharmaceutical event. I was tied up at the time," he said.
Do Your Homework
In 1976, in the midst of the Cold War, President Gerald Ford visibly baffled debate moderator Max Frankel — and many Americans — with his insistence that "there is no Soviet domination of Eastern Europe."
Don't Invite Unflattering Comparisons
Debate preparation can be like scouting an opposing team before a football game. That's just what Democrat Lloyd Bentsen did when he faced off against Republican Dan Quayle in the 1988 vice presidential debate.
Quayle, then 41, had been drawing comparisons to John F. Kennedy on the campaign trail. When Quayle brought up the comparison during the debate, Bentsen was ready with his classic and biting "you're no Jack Kennedy" monologue.
Say 'No' To Loaded Questions
During this year's Republican primary debates, Newt Gingrich showed on several occasions the value of angrily denouncing questioner and question. It's a lesson 1988 Democratic nominee Michael Dukakis would have been well advised to attempt when faced with the hypothetical question about whether he would change his opposition to the death penalty if his wife was raped and murdered. Some viewers saw the personal nature of the question as unfair; others took Dukakis' matter-of-fact response as emotionally callous.
Stick To Talking Points
In 1980, Ronald Reagan used his well-known debate one-liner, "There you go again," against President Jimmy Carter.
And then, four years later, he used it again, against Walter Mondale.
Remember, You're On TV
In 1992, while an attendee of a town hall debate asked about a stagnating economy, President George H.W. Bush checked his watch — a small gesture that critics said made him appear indifferent to the question.
In 2004, Democrats used President George W. Bush's "scowls" during his debates with John Kerry as a supposed example of his rudeness in this post-debate ad.
Be ... Likable
During the 2008 Democratic primary debates, Barack Obama sort of complimented Hillary Clinton with the line, "You're likable enough, Hillary," which some saw as a cheap shot.
It was reminiscent of 1984, when, at the vice presidential debate, incumbent George H.W. Bush seemed to be talking down to Geraldine Ferraro, the first woman on a major party ticket.
Copyright 2021 NPR. To see more, visit https://www.npr.org.


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Ariete O/S Push Rod Model 00102 is an original Guzzi spare part.
- For Galletto models
Sustainability | Sandro Mentasti Environmental Protection Program since 2007 |
Certifications | Quality Management system according to ISO 9001:2015 and Occupational Safety Management according to ISO 45001:2018 |
Ariete, ARI and Harri's products, while being of very high quality, may be subject to damage in case of impact or accident. Before using Ariete, Ari or Harri's products, please carefully read the instructions for use and installation. Sandro Mentasti Srl makes every effort to ensure that the information contained in this catalogue is correct and easy to understand, with some information specific to individual products, but accepts no responsibility for any misinterpretation. If you should require any further information, regarding assembly and/or conditions for use, please contact Sandro Mentasti Srl by e-mail at [email protected]. In any event, Sandro Mentasti Srl is not liable for any damage to property and/or persons caused during the use of its products, and neither for any damage resulting from incorrect use and/or use other than that for which the product was originally intended, and damage resulting from assembly errors and/or incorrect installation. Sandro Mentasti Srl manufactures its products directly, and markets them with the ARIETE, ARI and HARRI'S brands. The use contained within the catalogues of any original product codes bearing brands other than those mentioned above is intended as merely descriptive, as well as the possible use of trademarks and / or names of other manufacturers (for example, PIAGGIO®, HONDA®, YAMAHA®, SUZUKI®, KAWASAKI®, BMW®, VESPA®, KYMCO®) which Sandro Mentasti Srl is in no way connected. The only purpose of this use is to describe the accessory and/or the part.


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Stop & Shop Coupon Match Ups 08/24 – 08/30
Make sure you check out the Stop & Shop Coupon Policy. Note that these prices are based on circulars from Northern NJ. Some area may have slightly different prices so please check your circular. Also, some areas have gas rewards instead of instant savings deals.
New to Couponing? Make sure to check out the LRWC Beginners Section
- Click on the box next to the item you would like to buy at the store
- The item will be placed in your shopping list.
- The list will appear from the right bottom of this site
- Once you are done, click print.
- Note that if you leave this post, you will lose your list.
- Look for the to find the best stockpile prices
NOTE: If your catalinas do not print, the best thing to do it to contact Catalina Marketing. Their info is: 1-888-826-8766 or via email [email protected].
This list is for personal use only and is the property of Living Rich Media, LLC. Any use of this list for any other purpose is in violation of copyright laws.


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Athletics - 002 020 000 - 4 13 0Victor Martinez went 5-for-5, with a career-high four doubles, leading Boston's comeback.
Red Sox - 000 032 13x - 9 14 1
Martinez has had three other five-hit games: July 16, 2004 (3 HR, 7 RBI), July 4, 2006, and August 2, 2009. Martinez hit three doubles against the Twins about two weeks ago, on May 20.
Martinez doubled with one out in the fifth, Kevin Youkilis singled, and Adrian Beltre lined a three-run dong over the Wall, cutting Oakland's lead from 4-0 to 4-3. In the sixth, the first three Red Sox batters walked. Dustin Pedroia's GIDP tied the game and Martinez's ground rule double into the triangle gave the Sox a 5-4 lead.
A two-out walk by J.D. Drew, followed by Bill Hall's triple, made it 6-4 -- and the Sox batted around in the eighth to put the game on ice. With one out, Pedroia doubled, Martinez doubled, Youkilis singled; after David Ortiz flew out, Beltre singled and Drew singled. There were a couple of wild pitches, too.
Lackey (6-12-4-2-4, 116) allowed a small army of base runners, but stranded most of them, including seven in the 4th-5th-6th innings.
The Blue Jays led the Rays 5-0 after six innings, but Tampa got three in the seventh and (aided by five walks) four in the ninth and won 7-6. The Yankees beat the Orioles 3-1.
East: NYY 2.5 GB, TOR 4.5 GB, BOS 5.5 GB.Gio Gonzalez / John Lackey
Oakland is 28-24 and is 1 GA of the Rangers in the AL West.Scutaro, SS
Pedroia, 2B
Martinez, C
Youkilis, 1B
Ortiz, DH
Beltre, 3B
Drew, RF
Hall, LF
McDonald, CF
The A's have scored 205 runs and allowed 212 runs (expected record: 25-27). They went 16-12 in May despite scoring 99 runs and allowing 113. They have won eight of their last 10 games and 10 of their last 14. (Fangraphs' Matt Klaassen on the A's.)
Boston is 29-23, 5 GB Tampa Bay.
In his last four starts, Lackey has allowed 31 hits and 16 walks in 24.1 innings (6.29).
I've looked at some of those walks and they weren't really walks. I've gone back and looked. My control is not as bad as it seems. ... I'm going to be OK. I'm not worried about it.The A's have allowed only 21 earned runs in their past 10 games (27 runs overall). In six of the 10 games, Oakland has allowed 0 or 1 run.
Michael Silverman, Herald:
Red Sox starters were 6-6 with a 4.86 ERA in April, a perfect reflection of the team's overall mediocrity that month.Starters ERA:
But with Jon Lester leading the way, they rebounded in May.
APR MAY DIFFThe Red Sox traded Jonathan Van Every to the Pirates for minor league catcher Josue Peley. This will most likely be the last time you hear Peley's name (because he has hit .186/.241/.234 in two seasons of A ball).
Rays 2.76 3.40 -0.64
Yankees 3.41 3.94 -0.53
Blue Jays 4.02 4.46 -0.44
Red Sox 4.86 4.32 +0.54
Also at 7 PM:
Rays/Blue JaysOrioles/YankeesJune 1 in Baseball History
1918: Trailing the Yankees 5-4, the White Sox load the bases in the ninth inning with no outs. Chick Gandil hits a line drive to New York third baseman Frank Baker, who starts a game-ending triple play.
1923: The Giants score in every inning and beat the Phillies 22-8.
1925: Lou Gehrig pinch-hits for Pee Wee Wanninger, beginning his streak of playing in 2,130 consecutive games.Giants - 421 155 121 - 22 23 0
Phillies - 140 110 010 - 8 15 0
2000: Tomo Ohka of the Pawtucket Red Sox pitches a perfect game (on only 76 pitches!) against the Charlotte Knights, winning 2-0. It is only the 3rd perfect game in the 117 years of the International League. Three years later, on August 10, 2003, Bronson Arroyo of the Paw Sox will pitch the IL's 4th perfect game.


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Linda and Michael Hutcheon on "Four Last Songs: Aging and Creativity in Verdi, Strauss, Messiaen, and Britten"
By Linda and Michael HutcheonPosted in OtherBy Linda and Michael Hutcheon
As we entered our seventh decade (yikes!), we realized that there was now a new period of life, that time beyond the usual point of retirement, for which there were precious few models. Firmly believing that opera (our particular passion) offers a perspective on practically all aspects of the human condition, we decided to examine the later years and last works of several successful composers of opera. Our goal? An understanding of their last years within the context of their entire artistic life course—and of the role of creativity in these years.
Of course, our current culture is one that is highly commercialized, resolutely anti-aging, and decidedly death-denying. It purports (with appropriate purchases) to keep us young forever, as though that were possible. The reality is, however, that we all age (if we are fortunate), and our lives change: social roles alter; the decline of physical health and cognition become worries and possibly realities; the world around us changes, sometimes at our expense. We wondered how artists of previous generations dealt with these inevitable changes. Did their creativity permit them to maintain social roles in later years? Did their creative works give them a forum in which to address those issues of aging and mortality? And, most importantly, what could we learn from their examples?
These are the questions that generated this book about aging and creativity, concepts that for many people do not sit easily side-by-side. However, as the lives of artists like Michelangelo (1475-1564), Goethe (1749-1832), and Elliott Carter (1908-2012) attest, they most certainly can. The canonical composers whose later-life stories are told in this book—Giuseppe Verdi (1813-1901), Richard Strauss (1864-1949), Olivier Messiaen (1908-1992), and Benjamin Britten (1913-1976)—offer radically individual responses to this conjunction of later life and creativity.
Each of these composers was a musical icon in his own country and, in his later years, each wrote an opera in which concerns about creativity and aging coalesced. The composition of an opera always requires a major commitment of time and energy because of the size and complexity of the work. To undertake this task in their later years meant exposing their creative activities to new pressures. These were multiple and, more importantly, different from those experienced by their younger selves—ranging from ill health to the critical expectations that stemmed from their previous success. We found that their late works did indeed help them to explore creatively their own aging and mortality; however, all of them also had to face those challenges that came with their own personal aging.
In addition, the social, political, and aesthetic changes of their times—from World Wars to the rise of musical modernism—offered external challenges both to their creativity and to their sense of themselves as artists and persons. The book tells the stories of their different but equally creative ways of addressing all these challenges and changes. It looks at their attitudes to their own aging and creativity and also steps back and assesses both those late operas and their critical reception at the time of their composition and subsequently.
What did we learn? Well, just as each composer began his career in an individual manner, so each also ended it in a unique way—thus belying one of the powerful clichés about older age in the media and in popular culture: that all older people are the same. Rather it is the complexity of the interrelationship of aging and creativity that leads to the radical individuality of these artists' later years. Creativity in older life is not only possible, we learned, but a powerful aid in meeting the challenges of later life.
Linda and Michael Hutcheon's book, Four Last Songs is available now at these fine bookstores and online. Learn more about the book here.
Michael Hutcheon is Professor of Medicine, and Linda Hutcheon is University Professor Emeritus of English and Comparative Literature, both at the University of Toronto. Together they have written three other books using opera as their cultural vehicle of choice: Opera: Desire, Disease, Death (1996), Bodily Charm: Living Opera (2000), and Opera: The Art of Dying (2004).


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Skeeter's not impressed by ethics reform
Published 5:46 pm Friday, April 5, 2013
When the phone rang, I knew who was on the other end: Skeeter Skates, owner of Skeeter's Tree Stump Removal and Plow Repair in Greater Metropolitan Pooler. I can't tell you exactly why but the phone always sounds more urgent when Skeeter calls.
One thing about Skeeter Skates. He gets right to the point. Niceties aren't his style. "Hoss, I been busy sharpening plow shares for spring planting and ain't kept up with the politicians in Atlanta," he said. "They gone home yet?"
I told him that, yes, the legislature had finished their session and that I thought everybody was back home by now, telling their constituents what a difficult session this had been and what long hours they had put in on the people's behalf.
"Oh, my granny's knickers," Skeeter snorted. "They say that every year. The reason I called you is I heard the politicians finally passed some kind of law putting spending limits on those lizard-loafered lobbyists that feed them. I find that hard to believe, but I figured you'd know since you fancy newspaper boys keep up with that kind of stuff while the rest of us have to work for a living." Skeeter Skates doesn't have much respect for anyone that doesn't have grease under their fingernails, including those of us in the media.
I affirmed that the Legislature had passed legislation claiming to tighten up on lobbyist expenditures but that it was a rather shallow exercise. I told Skeeter the House and Senate seemed to care less about our attitudes toward ethics reform and more about one-upping the other body and guaranteeing themselves convenient loopholes.
If signed into law, lizard-loafered lobbyists could still spend $75 "per occurrence" on a state official, which means as many times as they like. They can buy unlimited food and booze where entire legislative chambers or committees and caucuses are invited, once every calendar year. Lobbyists will also be able to pay for trips for public officials and their staffs within the United States and a lot of goodies don't even have to be reported. Oh, and I added, lawyers who lobby are exempt from these rules. Go figure.
I paused, waiting for an explosion. Instead, Skeeter chuckled.
"You got to hand it to those folks," he said, "They are slicker than a quart of SAE 5W-20 synthetic blend motor oil." I concurred although I had no idea what he was talking about. "You know they ain't gonna jump off that gravy train. They just went through the motions so they can come home and tell us how they heard us fussing about all the money lobbyists spend on them. They can say they did what we told 'em to do and then they can keep on getting wined and dined and take fancy trips like they used to. Dang, they are sharper than a set of stump-cutting teeth, ain't they?"
I didn't say anything because I know less about stump-cutting teeth than I do motor oil, but I agree with Skeeter Skates. Politicians aren't going to give up any more goodies than they have to, no matter how mad we get. They consider this stuff an entitlement.
"Hoss, I know you ain't never done a hard day's work in your life," Skeeter said. I have quit trying to convince him that writing columns is not as easy as he thinks. Every time I do, he invites me to come to Pooler and grind an oak stump with him. "But you just might be able to finally do something worthwhile." I was all ears.
"The politicians think they have pulled a fast one over on us," he said, "I want you to keep this issue on the front burner. Tell your readers which politicians are being wined and dined by lizard-loafered lobbyists. Let them know that the people of Georgia ain't as dumb as they think we are and that they haven't heard the last of us. Keep your readers fired-up and fearsome. I am counting on you, son."
I thanked Skeeter profusely for the idea and wasn't about to tell him I had already thought of that. Being a stump removal and plow repair professional, Skeeter Skates doesn't like to think anyone is as smart as he is.
As he hung up, it occurred to me that most Georgians are probably as disappointed and disgusted as he is. What a shame. And what the legislature didn't do about ethics reform is even more shameful.
You can reach Dick Yarbrough at email@example.com or P.O. Box 725373, Atlanta, GA 31139.


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Dr. Eeling Elaine Goh, OD 640 E. Deer Springs Way, Ste 140 North Las Vegas, Nevada 89086 P: 702-651-2000 F: 702-651-2002
A New Hope For Presbyopes Varilux lenses are an exciting new weapon in the fight against presbyopia (a natural eye condition that affects the eye's ability to bring near objects into focus). These lenses use revolutionary technology so presbyopes can see near, far, and everything in between. Millions of people with presbyopia or Long-Arm Eyes including current bifocal and trifocal wearers now see the way they were meant to again thanks to these amazing eyeglasses. Take Comfort Varilux lenses enable your eyes to make a smooth, gradual transition when you change your focus from near to intermediate to far vision. Unlike bifocal lenses, Varilux lenses eliminate the line that creates an abrupt, annoying vision change from near to far vision. The added comfort of Varilux is achieved with an increased field of vision. This larger vision field reduces unnecessary head movements both vertically and horizontally, which means you can assume a more natural, comfortable posture when viewing objects at close and intermediate ranges.
With Varilux lenses, head movements are reduced to only half as much. The gradual and regular distribution of power characteristics in the periphery of the Varilux lens allows for very comfortable vision in a lateral, side-to-side gaze. The Varilux wearer enjoys larger fields of vision with less head movement.
Near the age of 40, a condition known as Presbyopia develops. It's a natural part of aging which makes it difficult to focus on things close. Since the days of Ben Franklin, the solution to this has been bifocals. These types of lenses are now outdated. In addition to an unsightly line, their biggest limitation is that there is no clear vision at intermediate distances (such as a car dashboard, shelves at a grocery store, bank ATM machine, computer screen, etc.). Varilux is a progressive addition lens (PAL) that give you outstanding vision at all distances (far, intermediate and near) without any visible bifocal line. There are lenses that imitate some of the basic design concepts of Varilux lenses, but it can not be duplicated. Varilux's multi-patented lens design gives you a wider range of vision with less head movement. It has the least amount of peripheral distortion ever.Varilux lenses are an excellent choice even for those who are active with sports or even for those who work at a computer.


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Selling for Top Dollar! Did you know? The best chance for selling your property is within the first seven weeks! Studies show that the longer a property stays on the market, the less financial return the seller will net. There are 5 main factors to achieving your goal of getting top dollar for your property. Factor 1: PRICINGIt is very important to price your property at a competitive market value right when you list it. The market is so competitive that even over-pricing by a few thousand dollars could mean that your house will not sell. I have found your first offer is usually your best offer. An overpriced home:
When you think about it, 80% of the marketing is done when we decide on what price to list your home. For people unwilling to list a property at current market value, I usually recommend holding off on putting the property on the market for awhile. Factor 2: CLEANINGMost people are turned off by even the smallest amount of uncleanliness or odor when buying a home. Sellers lose thousands of dollars because they do not adequately clean. If your house is squeaky clean, you will be able to sell your home faster and net hundreds, if not thousands, of dollars more. If you are planning on moving, why not get rid of that old junk now so that your house will appear larger? Make more space! Odors must be eliminated, especially if you have dogs, cats, or young children in diapers, or if you are a smoker. You may not notice the smell, but the buyers do! Most agents have a difficult time communicating to their sellers about odor. If you employ an agent to get the most amount of money for you, please don't take offense if he/she must confront you about odor problems. Factor 3: ACCESSTop selling agents will not show your home if both the key and access are not readily available. They do not have time to run around town picking up and dropping off keys. They want to sell homes! The greatest way to show a house is to have a key! When your home is being shown, be sure to do the following:
Paint is your best improvement investment for getting a greater return on your money. Paint makes the whole house smell clean and neat. If your house has chipped paint, exposed wood, or the paint looks faded, it is time to paint. If your carpet is worn, dirty, outdated, or an unusual color, you may need to seriously consider replacing it. Many houses do not sell because of this problem. Don't think that buyers have more money than you do to replace carpet. They don't. They simply buy elsewhere. Factor 5: CURB APPEALThe first impression a buyer gets of your home is from the curb. Your front yard immediately reflects the inside condition of your house to the buyer. People enjoy their yards. Make certain that the trees and bushes are trimmed so the house can be seen from the street. Have the grass mowed, trimmed and edged. Walkways should be swept. The front door should be freshly painted or freshly stained. Clean away debris. Remove parked cars. This all adds to curb appeal. If a buyer does not like the outside, they may not stop to see the inside! Well, now you know all of the 5 main factors to getting top dollar for your property:
If you carefully consider these factors, you will maximize your chances of selling your property within the first seven weeks for top dollar! |


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If you've received a DWI in Grant County, New Mexico call 800-852-8005 or fill out contact form today to speak with a DWI lawyer in Grant County, New Mexico for immediate help. Being convicted of a DWI in New Mexico can have serious repercussions in your life. It's very important that you contact a DWI attorney to see how you can prepare to handle this difficult time. The DWI attorneys on DWI.com handle drunk driving defense cases in Grant County and throughout New Mexico. Call now for immediate help with your DWI case.
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Getting a DWI in Silver City, New Mexico can be a very scary event. Taking your DWI or drunk driving case through the court process can be even more intimidating. You will need a qualified DWI attorney in Grant County who knows the DWI laws in New Mexico. The experienced DWI lawyers on DWI.com can help you with the ins and outs of the DWI process in New Mexico and can guide you through it step-by-step. If you have been arrested for a DWI in Grant County, you need a DWI lawyer in Grant County that knows the drunk driving laws. The DWI attorneys on DWI.com are ready to handle your drunk driving defense case. For a free consultation for your DWI call 800-852-8005 or complete the simple consultation form.
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After you have been arrested for a DWI in Grant County you will have many court appearances. This is another reason to hire a qualified DWI attorney in Grant County. There is a first appearance and many subsequent appearances, or pretrial's, that will be scheduled. These court dates are crucial to your DWI defense. An experienced DWI lawyer will use these appearances to get valuable information regarding your DWI arrest.
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Being arrested for DWI in Grant County, New Mexico can be very costly. A DWI arrest can result in fines, vehicle impoundment, license suspension and even jail time. Making the right decision when choosing from DWI lawyers in Grant County, New Mexico for your drunk driving defense can mean the difference in thousands of dollars saved and/or time spent in jail. Make sure to choose a DWI lawyer with a proven track record and a team of qualified people who work for you. Please call 800-852-8005 for a free no obligation consultation or complete the contact form.
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