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Ashika Soni
| Zuletzt Online: 25.05.2022
Ashika Soni
Registriert am:
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subset: commoncrawl


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A Message From Gail
Through my blog and website, I hope to share beauty, laughter, inspiration, aging & midlife lessons and advice on dealing with menopause. I will also devote time to integrative health and healing tips and news. I want feedback and questions because, while we may be sharing the journey, every woman has her own experience and her own story.
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Teens Can Also Enter at www.myspace.com/teenchoiceawards
for an Opportunity to Assist FOX's Official Photographer
FOX and MySpace are launching an exclusive online search for one teen guy and one teen girl to hand out the surfboard trophies on stage at TEEN CHOICE 2010 airing Monday, Aug. 9 (8:00-10:00 PM ET/PT) on FOX. In addition, teen fans can also enter for the opportunity to assist FOX's official red carpet photographer! Contestants can enter by visiting the official TEEN CHOICE 2010 MySpace profile at www.myspace.com/teenchoiceawards.
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Untold Tales of the
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In this dazzling new work of American history Kenneth C. Davis, one of the country's most popular historians illuminates some of the "hidden history" the schoolbooks left out.
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Writing from a rich font of scholarship, seasoning the facts with wit, irony and a novelist's eye for telling detail, Kenneth C. Davis has conjured back to life some of the most fascinating figures of America's founding decades. All-but-forgotten heroines (Hannah Dustin, Anne Hutchinson, Mary Rowlandson) take their rightful place onstage alongside "great men" (Washington, Revere, Daniel Shays) whose names, until Davis restored them to life, had long eclipsed their striking words and deeds. This is American history in the vibrant narrative tradition of David McCullough and H. W. Brands. —Ron Powers, co-author of Flags of Our Fathers
Paul Revere didn't shout out, "The British Are Coming" as he galloped through the night on his famous ride. What did he actually say? Read Kenneth Davis' "Hidden History" and you'll find out. You'll learn lots more, too, in this engaging book of true, and often important, stories from U.S. history. These aren't the tales you'll find in most textbooks. —Joy Hakim, author of A History of US
Ken Davis now takes us on a journey into America's past, bringing to light little known tales that shaped the nation....Once again Ken Davis proves that what you don't know can be shocking. Do yourself a favor. Read this book. —Richard M.Cohen, author of Strong at the Broken Places


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The View From the Top - Global Heads Summit Report
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Recent events have demonstrated that Earthquake Induced Liquefaction Disasters (EILDs) are responsible for tremendous structural damages causing in some cases half of the economic loss caused by earthquakes. With the causes of liquefaction being substantially acknowledged, it is important to recognize the factors that contribute to its occurrence, to estimate hazards, then to practically implement the most appropriate mitigation strategy considering the susceptibility of the site to liquefaction, the type and size of the structure. The LIQUEFACT project, funded by the EU within the H2020 – DRS 2015 call (Research Innovation Action), addresses the mitigation of risks to EILD events in European communities with a holistic approach. The project deals not only with the resistance of structures to EILD events, but also with the resilience of the collective urban community in relation to their quick recovery from an occurrence. The LIQUEFACT project sets out to achieve a more comprehensive understanding of EILDs, the applications of the mitigation techniques, and the development of more appropriate techniques tailored to each specific scenario, for both European and worldwide situations.
LIQUEFACT project Brochure


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"Psychedelic Hibiscus"
Regular price
From my most recent "Flower Concentration" series depicting the centers of individual flowers as an aid in single point concentration ultimately leading to meditation and bliss, 2017. Archival pigment print 11" x 15.5." Printed by James Wojcik on 100% acid free Canson Baryta Photographique paper in an edition of 50. Signature, edition number, and authentication stamps on verso. Matted on 16" x 20" 4 ply 100% acid free white Rising Museum board. Ships within 4-5 days.


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Title: External Forces
Author: Deborah Rix
Publisher: Dime Store Books
Pages: 268
Language: English
Genre: Young Adult Science Fiction
Format: eBook
Purchase at AMAZON
Treason, betrayal, and heartbreak.
A lot can happen to a girl between her first kiss and her first kill.
It's 100 years since the Genetic Integrity Act was passed and America
closed its borders to prevent genetic contamination. Now only the
enemy, dysgenic Deviants, remain beyond the heavily guarded border. The
Department of Evolution carefully guides the creation of each generation
and deviations from the divine plan are not permitted.
When 16-year-old Jess begins to show signs of deviance she enlists in
the Special Forces, with her best friend Jay, in a desperate bid to
evade detection by the Devotees. Jess is good with data, not so good
with a knife. So when the handsome and secretive Sergeant Matt Anderson
selects her for his Black Ops squad, Jess is determined to figure out
As her deviance continues to change her, Jess is forced to decide who
to trust with her deadly secret. Jess needs to know what's really out
there, in the Deviant wasteland over the border, if she has any hope of
making it to her 17th birthday. Because if the enemy doesn't kill her
first, the Department of Evolution probably will.
I haven't slept in forty-eight hours.
It's part of the Special Operations Assessment and Selection course,
twenty-eight days of grueling work. The two days of no sleep are meant
to disorient us, part of discarding our former selves. There are three
hundred of us trying to figure out how to do what we're told, when we're
told to, and how to do it correctly. Jay and I weren't assigned to the
same platoon, which was unexpected. I'm in the "civilian" platoon; we're
the ones with skills that don't generally require brute force. I think
Jay is in some kind of elite group because I haven't seen him, I've only
seen the G-men platoon. They are all about brute force; they're the
ones that opted for genetic enhancement at age thirteen without the
supervision of the Devotees. But Special Forces is, well, special, so
they have to prove they've got more than muscle and I've gotta prove
I've got more than a quick mind.
If I don't make it to Special Forces, my life expectancy in the
regular army could be pretty short. And if I'm a complete washout, I'll
have to go to my assessment with the Devotees and they'll find out about
me, making my life expectancy even shorter. I seriously need to pass.
Zero dark thirty is when I have to haul myself out of bed in the
so-called morning. My drill sergeant has been yelling at me for most of
the past two days. The word "why" has been surgically removed from
everyone's vocabulary. Any individual hesitation in following orders
means at least one private is getting smoked, if not the whole platoon,
which usually means push-ups. We've done a lot of push-ups. I stare
straight ahead as the drill sergeant walks by me and continues down the
row of privates. I made the mistake of "eyeballing" him yesterday.
Never. Eyeball. A drill sergeant.
First Chapter:
Three weeks earlier – May, 2125
My mother thinks I'm a Deviant.
It's the kind of thing that can really throw a girl for a loop.
The Devotees missed it when I was born, she said, but one day they
would come for me. That was a few years ago, she didn't know I was home
when I overheard her; I got out of there lickety-split.
And it's not as if I haven't noticed the way my mother looks at me
sometimes. If they had taken me when they had the chance, maybe her
other baby would still be with her. I'm pretty sure that's what goes
through her head when she looks at me.
So the early assessment notice wasn't entirely unexpected. It
doesn't necessarily mean anything. Lots of kids are called for early
assessments and nothing happens; they show up at school the next day.
Some of them are all excited because they got called to become a
But some of them, well, they don't come back.
I'm in the parking lot of my high school, West Liberty. It's prom
night, and I came with my best friend, Jay. He's still inside; he likes
this sort of thing. I haven't told him the early assessment notice came
this afternoon. I didn't want to ruin tonight for him. The humidity has
made my dress even more uncomfortable than it was inside. Jay owes me.
At least he won't mind if I go home; it's not that kind of date.
A car door slams shut. There aren't a lot of kids who can afford the fuel to drive their own car to the prom.
Uh-oh. Blake.
I take a step back. Blake is a popular kid, with the right look, the right home, the right pedigree.
Despite my attempts to blend in and stay in the background, Blake
noticed me this year. When I didn't respond like all the other girls do,
I became his target.
His car keys jangle as he drops them in his jacket pocket. I stand still; maybe he hasn't seen me.
"Hey, freak," he calls as he comes around the blue pickup I was hoping would shield me. "Not leaving, are you?"
I smell alcohol as Blake backs me up against the truck.
His slicked-back hair smells slightly astringent, and his tongue
slides over his upper lip as he looks me over from top to bottom. A
shiver of revulsion goes through me. I can't imagine what girls like
about him. I can hear some voices, but they're at the other end of the
parking lot. It's just me and Blake.
"I've got an early graduation present for you," he says quietly. His
face is close to mine, and I can see beads of perspiration on his
forehead. Slick from the humidity, his hand glides down my bare
shoulder, as if he's entitled to touch me.
I don't think I want a present from Blake.
I'm surprised when my hand moves. There is a wet sound as Blake's head snaps back.
Blood spurts, and it seems as if time has gone into slow motion. The
blood sprays toward me. I move my head to the side to avoid it, and
watch it slowly drift by, suspended in the air.
I turn back to Blake and a thrill zips through me. Thick, glossy
blood creeps down his chin from his mashed nose. His mouth is open in
shock; blood colors his teeth and gums. He moves sluggishly, and each
blink seems to take effort.
Drip by slow drip, the blood falls from his chin onto his shirt.
Fascinated, I watch each droplet burst on his crisp white collar.
A wet plonk hits my forehead as a sudden coldness envelops me. The
grin I'm shocked to find on my face sags. Fat droplets of rain release
the pressure in the air and mix with the blood on Blake's shiny shoes.
Hands to his face, he doubles over as time suddenly speeds up again.
The rain pelts down now. I take two steps to the side and run. I hear a
sob and realize it's me.
What just happened?
It's the morning after prom, and Jay saunters along beside me as we
walk back to my house. I met him half way, as per my usual. His t-shirt
is a bit wrinkled, but that's on purpose, to go with jeans that are a
little baggy in back. He's over six feet and gets asked if he's a model,
which he laughs at, but I know he's pleased. He could be quite popular
if he wanted, but he hangs out with me instead.
Jay and me are Fifth Generation. We're the ones born between 2100 and
2120. We found each other in the seventh grade. We were the last two
kids left when we all paired up for gym class. He asked me why I wasn't
moving when we were supposed to be heading out to the field. I explained
that I was trying to activate my special powers so that I could use
them to transport me far away. Usually that kind of talk would send kids
running, and they'd whisper that I must be a Deviant. But not Jay. He
blinked at me, then asked if I would take him with me, should my special
powers ever actually work. We've been best friends since, and tell each
other pretty much everything.
"So, can you come to the thing?"
Uh oh.
I think I'm supposed to know what he's talking about.
"Uh, when is it again?" I stall for time. What thing?
I push my hair behind my ears to help me think. It doesn't always
work. I have shoulder-length brown hair, parted on the side. My
no-nonsense look is how I think of it. I still don't know what the thing
"Wait. Jess. You're joking, right?" Jay says with a laugh that's on the edge of anger.
"I'm sorry." I do my best pleading cringe. "I'm a little distracted."
The early assessment and whatever that was with Blake last night are
the distractions. I can't quite believe I punched him, broke his nose by
the look of it. He's probably going to have two black eyes. But more
than that punch, as surprising as it was, is the way time seemed to slow
down around me. I want to say it was shock, or some kind of temporary
fugue state, but that's not what it was.
Something happened.
"My mother's thing, remember?" Jay practically yells at me.
"Oh, that," I say with relief. Jay's mother is hosting a party to
celebrate his seventeenth birthday. That's what the thing is. It's going
to be awful.
"We met up, what? Five minutes ago? And you're already trying to
drive me crazy?" He pinches my butt. Hard. He's pretty worked up about
this party.
I yelp and dance around. "No way. You are not blaming your crazy on
me." I give him a solid punch in the gut. "You had years of exposure to
your mother before we even met."
I go rock climbing, so my arms are strong. I've never needed to go to
the gym to work out and "stay in shape" like some of the other girls
do. I'm five feet ten and a half inches and the coach at school said I
have an athletic body; he tried to get me to go out for track and field.
I don't like the idea of people watching me like that.
But hitting Jay is like hitting concrete. He doesn't even notice my punch.
"And of course I'm coming, I already told you. That's why I didn't
know what thing you were talking about. I thought you meant some other
"You didn't actually confirm with my mother," he complains, "and I know how you feel about people, in general."
"I don't have a problem with people, in general. Just the idiots," I say. "And your mother."
It's kind of a toss-up, I suppose. A mother like mine, who actively
avoids you and has already decided you're not worth the effort, or one
who pays too much attention and has too many expectations.
Jay nudges me as an unfamiliar dark-haired boy, a bit younger than we
are, walks toward us. He doesn't look right at us, but he flashes us
two crossed fingers with his right hand.
I look up ahead and see them coming our way. Three Devotees. Jay and I
mumble the greeting in unison, "Blood of our blood, flesh of our flesh,
soul of our soul," and we look down as they brush past us in their
crisp white lab coats. It's best not to be noticed.
The Devotees work for the Department of Evolution —everyone just
calls it Devo— and they do the work of Creation in partnership with God.
The Department of Evolution is under the direction of Secretary Galton.
Basically, she's God's voice here on Earth. In the midst of the genetic
revolution a hundred years ago, when the Genetic Integrity Act closed
America's borders, strict protocols for border biosecurity were
instituted to stop genetic contamination. But we were still in danger of
being overrun by the Deviants on the other side. Galton took control,
ordered the fortification of our borders and gave the military the
authority to do what they needed to do. Most people agree; she did what
was necessary for our survival by relinquishing certain powers to the
military to ensure our protection. Including the ability to create
proprietary, genetically enhanced soldiers. The G-men. Since then,
Galton has been leading us through the current stage of evolution,
Regenesis, removing unwanted traits and improving and enhancing our best
traits with the guidance of God.
In Social Biology class, Devotee Theresa taught us that we must all
work for the common good, whether we like it or not. The less
intelligent are more fertile and must be discouraged from breeding. Only
those with desirable traits are allowed to produce the next generation.
There's this section, practically a whole semester of tenth grade,
where we studied pedigree charts, and DNA, RNA, proteins, and ribosomes.
DNA is a double helix that carries the genetic information for all
life. If only one part of one gene is wrong, it can create a whole
generation of imbeciles, and that is not in God's plan. Or in Devo's
plan. All Devotees have that DNA double helix tattooed on their forearm,
as a constant reminder of their purpose in life.
That's what the crossed fingers warning represents, the double helix tattoo.
We come up to the old Palace Theater. It's been shut down for a long
time, and the large sign that hangs out front lost its first A, so it says PLACE.
Someone found a way in down the side alley, and now kids hang out
there. They say, "Meet me at the place." If they're overheard or an
adult sees a message, it only says "the place." So far it's stayed
secret. I've heard they have illegal sim-seats in there, ones that can
scramble the biometrics and mask what you're doing.
"Jess," Jay says as he slows right down, "something's wrong."
"It's time to wake up!" a skinny boy with curly red hair yells. He's
standing on a wooden crate, and people are hesitantly milling about.
"People are dying! Out there, children are starving, and you send them
poison. People are sick, and you send them plagues. The blood of our
blood is on your hands!"
There are gasps at his blasphemy, but a few people cautiously move
toward him in morbid fascination. His eyes are wild, there's spittle on
his lips. Jay grabs my arm to tug me backward.
When the bullet enters the boy's left temple, it's as if he doesn't know it's there for a moment.
He's about to yell, his mouth opens, his lips form a word he will
never say. Then he topples backward, and I hear the terrible thud as his
head hits the ground. The people closest to him quickly step back. No
one screams, no one looks up to see the Guardian with the rifle on the
roof across the street. Everyone wants to blend in.
Another Guardian comes toward the Palace. The Guardians work for Devo
and protect us from Deviants. The stiff collar somehow makes his
slightly rumpled, brown uniform shirt look crisp. The yellow double
helix is on the front of his cap, and above his left shirt pocket.
"Move along," he says. "It was just a Deviant."
We all know that the plain fact of his yelling out crazy stuff in the
street like that is proof of his deviance. It's what happens sometimes,
but it's most prevalent during adolescence. The deviance manifests and
people become dangerous, psychotic Deviants, intent on our destruction.
The Guardian rests his hand on the butt of the holstered pistol
hanging from his belt and waits for the brown panel truck with the
whooping siren we can hear approaching.
Jay swears at him under his breath and keeps hold of my arm. We hurry
off with the rest of the crowd, wanting to move as far away as
possible. I look back in time to see somebody dart in behind the
Guardian, dip a hand in the boy's blood, and leave an angry red
handprint on the front of the Palace Theater. A red hand. I've heard the
whispers but never thought it was true. As I stare at it, I bumble into
Mrs. Yamoto, one of my neighbors. She walks fast, gripping her
daughter's hand tightly. Last year, I saw the brown truck with the
double helix on the side parked in front of her house. The Guardians had
come to take her son.
That was his name.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
A fibroblast is a type of cell that synthesizes and maintains the extracellular matrix of many animal tissues. Fibroblasts provide a structural framework (stroma) for many tissues, and play a critical role in wound healing. They are the most common cells of connective tissue in animals. Fibroblasts were first discovered by Dr. Matthias De Oliveira in 1968.
The main function of fibroblasts is to maintain the structural integrity of connective tissues by continuously secreting precursors of the extracellular matrix. Fibroblasts secrete the precursors of all the components of the extracellular matrix, primarily the ground substance and a variety of fibres. The composition of the extracellular matrix determines the physical properties of connective tissues.
Fibroblasts are morphologically heterogeneous with diverse appearances depending on their location and activity. Though morphologically inconspicuous, ectopically transplanted fibroblasts can often retain positional memory of the location and tissue context where they had previously resided, at least over a few generations.
Unlike the epithelial cells lining the body structures, fibroblasts do not form flat monolayers and are not restricted by a polarizing attachment to a basal lamina on one side, although they may contribute to basal lamina components in some situations (eg subepithelial myofibroblasts in intestine may secrete the α-2 chain carrying component of the laminin which is absent only in regions of follicle associated epithelia which lack the myofibroblast lining). Fibroblasts can also migrate slowly over substratum as individual cells, again in contrast to epithelial cells. While epithelial cells form the lining of body structures, it is fibroblasts and related connective tissues which sculpt the "bulk" of an organism.
Embryologic origin
Like other cells of connective tissue, fibroblasts are derived from primitive mesenchyme. Thus they express the intermediate filament protein vimentin, a feature used as a marker to distinguish their mesodermal origin. However, this test is not specific as epithelial cells cultured in vitro on adherent substratum may also express vimentin after some time.
In certain situations epithelial cells can give rise to fibroblasts, a process called epithelial-mesenchymal transition (EMT).
Conversely, fibroblasts in some situations may give rise to epithelia by undergoing a mesenchymal to epithelial transition (MET) and organizing into a condensed, polarized, laterally connected true epithelial sheet. This process is seen in many developmental situations (eg. nephron and notocord development).
Structure and function
Fibroblasts have a branched cytoplasm surrounding an elliptical, speckled nucleus having one or two nucleoli. Active fibroblasts can be recognized by their abundant rough endoplasmic reticulum. Inactive fibroblasts, which are also called fibrocytes, are smaller and spindle shaped. They have a reduced rough endoplasmic reticulum. Although disjointed and scattered when they have to cover a large space, fibroblasts when crowded often locally align in parallel clusters.
Fibroblasts make collagens, glycosaminoglycans, reticular and elastic fibers, and glycoproteins found in the extracellular matrix. Growing individuals' fibroblasts are dividing and synthesizing ground substance. Tissue damage stimulates fibrocytes and induces the mitosis of fibroblasts.
Secondary actions
Mouse embryonic fibroblasts (MEFs) are often used as "feeder cells" in human embryonic stem cell research. However, many researchers are gradually phasing out MEF's in favor of culture media with precisely defined ingredients of exclusively human derivation. Further, the difficulty of exclusively using human derivation for media supplements is most often solved by the use of "defined media" where the supplements are synthetic and achieve the primary goal of eliminating the chance of contamination from derivative sources.
See also
External links
ca:Fibroblast de:Fibroblast fa:فیبروبلاست he:פיברובלסט it:Fibroblasto lt:Fibroblastas mk:Фибробласт nl:Fibroblast sk:Fibroblast sr:Фибробласт sv:Fibroblast


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Rebecca Uth
"The human being is the focal point of everything I do. I want to seduce, wonder and change people through objects. To me, design must relate to the body and soul and must be felt, tasted and seen – sometimes unexplained and on an inaccessible level, sometimes just an everyday wonder." Rebecca Uth established Ro in 2013 and is creative Director of the company. In her role as artistic director, she works closely with the selected designers to curate a holistic and innovative collection that manifests Ro's universe. A universe that focuses on the artistic process and on objects that only becomes more beautiful with time. Rebecca Uth is trained as an industrial designer at the Danish Design and designs herself products for the collection.


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Introduce your business and tell us your story: How did you decide on what to sell, and how did you source your products?
I am a mother of two kids under 4 and get a LOT of emails from baby and parenting websites advertising products. I came across a similar product to the one I sell and I thought, I'm not paying that much for that!! So, having a business background, I said to myself what else have I got to do on maternity leave but raise two children? I know, I'll start a small business! I wanted my products to be Australian made and Australian owned, so I spent a significant amount of time doing research to get the best price I could. Initially I was quoted upwards of $200 per unit just for the board!! No.....not cool, so I kept going and brought my costs down so I could stay in Australia. Of course it is cheaper overseas, but having the knowledge that my supplier is just up the road bring me great peace of mind when it comes to quality control.
How did you earn your first sales? Which channels are now generating the most traffic and sales for you?
Definitely through my friends. My mother's group from my first child has been really supportive, both in sales and in just spreading the word in general. Other than friends, local markets have been a really great sales channel for me. Facebook is definitely the channel driving most traffic to my store. Both through paid ads and posting in buy swap and sell pages. It has been really effective.
Tell us about the back-end of your business. What tools and apps do you use to run your store? How do you handle shipping and fulfillment?
I use a variety of apps to help run my store, but in particular I like Receiptful as it gives the customer a great post-purchase look into the business. The receipts look professional and the ability to include a discount code helps with post sales conversions. I also like Shopimap because it shows potential customers where your sales have gone. I'm a one man (or woman) band so I handle all of the packaging myself. I use a courier company to deliver my goods as they're quite a big carton and won't be shipped by our national carrier. I love getting orders and writing a personal message to each customer. I think it's so important to show your customers some love!
What are your top recommendations for new store owners?
Oh, what have I learned? Patience! Being patient in getting the business off the ground from an admin perspective, getting sales, managing family and business life. It has been difficult but the success in knowing that you've built a business by yourself is truly heartwarming :)


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Obsessively Crafted
Low Profile Construction
Designed to provide maximum coverage and stay in place just below the edge of your shoes
No Slip Heel Grip
Stay-Put Heel Grips ensure your socks stay in place and never fall down when your shoes are on or as you take them off
Soft Memory Yarns
Manufactured using 200 need construction with ultra-soft combed cotton that adapt to your foot with each wear
Rip Protection
Proprietary constructed to eliminate holes by double re-enforcing areas that experience the most friction and tear
Our #1 priority here at Soxy is your happiness. Which means we stand by our product 100%, no matter what. If you have a problem, we'll solve it. Refund it. Replace your order. Whatever it takes.


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Qty : 1
Do you admire stylish things? Let your favourite dog enjoy wearing such accessories on! Praise him with this awesome leather dog collar with studs from FDT Artisan. This gear is made for those who just adore stylish things. In this exceptional collar, your dog will have more severe, but stylish look. Your cute four-legged friend will get the finest treatment when wearing this accessory. Full grain leather is safe and absolutely eco-friendly.
Click on the pictures to see bigger image
Fancy walking dog collar of leather with inimitable adornments
Rust-proof traditional buckle on exceptional natural genuine leather dog collar
Rust resistant traditional buckle on unusual full grain genuine leather dog collar
Key features of this Dog Collar:
Intended use of this Dog Collar:
Sizes available:
Available colors:
Corrosion proof buckle on decorated genuine leather dog collar
Please be advised that:
Natural leather was chosen to provide maximum comfort and safety while wearing. The material is perfectly oiled that saves it from cracking. Among the best features of full grain natural leather are good adjustability, tear-resistance and sturdiness. The layer of leather is rather thick that doesn't allow the tool damage. It helps you to walk even big and massive dog safely. Rounded and smooth edges of the collar are non-cutting and don't rub the dog's skin. Besides, full grain natural leather doesn't consist of any harmful elements being absolutely eco-friendly.
Exceptional leather dog collar for stylish walking your doggie
This is how the package looks
Order a present for your dog
* 1-5 business days on average once the order is shipped (not including holidays and weekends)** 3-5 business days on average (not including holidays and weekends)
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You can return all items (except close-outs and custom made products) within 21 days after delivery. Please, contact us before you send item/items back to receive a return/exchange authorization number.


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Free Brinker 3-Choice $50 Gift Card Get Brinker 3-Choice $50 Gift Card for free with Swagbucks
Details on the Free Brinker 3-Choice $50 Gift Card
Brinker International is the premier casual dining restaurant company in the world and has received numerous accolades through the years for its outstanding performance.
Brinker International has been called the "mutual fund of casual dining" - stemming from their powerful and unprecedented portfolio of outstanding concepts which includes Chili's Grill & Bar, Romano's Macaroni Grill, On The Border Mexican Grill & Cantina, Maggiano's Little Italy, Corner Bakery Cafe, and Rockfish Seafood Grill.
Founded in 1975, Brinker International has grown to over 1,500 restaurants worldwide. Brinker International's mission is to be the very best in the business. Their game plan is status go ... they are constantly looking ahead, building on their strengths, and reaching for new goals.
To view a sample e-Gift Card and a complete list of the Terms & Conditions click here.
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I think this should clear up the confusion and I appreciate Stephen's efforts to clarify this for us. In summary, non-subscribers will have full access to their list of DNA matches and "Genetic Ethnicity" results, continue to receive new matches and updates to the admixture analysis, be able to view shared surnames, birth locations and a limited tree view for their matches and (as we have all been hoping) have the ability to contact their matches through Ancestry.com. So, this confirms that there is still a lot of functionality, even without the subscription. In my opinion, outside of traditional genealogy research and strictly in regard to the DNA test, the most important additional benefit that only comes with the subscription is the ability to explore your matches' full Ancestry.com family tree. This can be very important when attempting to confirm a common ancestor with a match that might fall just beyond a genealogical brick wall.
If anyone has additional questions, please ask them in the comments section below and I will try to make sure they get answered.
I will also be following up with a post with more technical details about the test from my recent conversation with Ken Chahine, General Manager of AncestryDNA.


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Many of us have had sinus-related headaches, right? You know, these are the headaches that hurt over the sinuses (above the eyes or in the cheek bones next to your nose) and when you blow your nose, it's not pretty! Sinus infections often lead to sinus headaches – wouldn't you say that's a true statement?
A November 2011 study begs to differ. Researchers took 58 patients with a diagnosis of "sinus headache" made by their primary care physician and asked them the following questions:
- Have you had a previous diagnosis of migraine or tension-type headache?
- Is their clinical evidence of a sinus infection during the past 6 months?
- Is there the presence of "mucopurulent secretions" (that's the "not so pretty stuff" when we blow our nose)?
All 58 patients clearly seemed to have chronic sinusitis with an acute flair up and were given complete thorough examinations by a neurologist and an ears, nose, and throat specialist (otolaryngologist) on a monthly basis for 6 months during treatment. Surprisingly, 68% really had migraine headaches, 27% really had tension-type headaches, and 5% really had chronic sinusitis with recurrent acute episodes. Treatment during the 6 months included antibiotic therapy in 73% of the patients with tension-type headache and 66% with migraine. Sinus endoscopy (taking a look up the sinuses with a scope – ouch!) was performed in 26% of the patients, and therapeutic nasal septoplasty (surgery!) was performed in 16% of the migraine patients and 13% of patients with tension-type headache (a pretty BIG mistake, wouldn't you say?). The conclusion was that many patients with self-described or primary care physician diagnosed "sinus headaches" have no sinonasal abnormalities but instead, met the criteria for migraine or tension-type headache.
So, what does this mean? Well, for one thing, too many antibiotics are prescribed for tension-type or migraine headaches and have no place in the treatment process of these two common headache categories. Side effects of antibiotics include (but are not limited to): stomach and intestinal irritation, nausea, and if one is allergic to the antibiotic, a potentially life-threatening condition called anaphylactic shock. Let's not forget to mention that sinus surgery was performed in 29% of the cases where the sinuses were NOT causing the headaches and we all know the risks of undergoing anesthesia and surgery can include death and infections, among other problems.
Several publications have described chiropractic as a wise choice for the treatment of headaches. For example, see the large review of the literature on the "Effectiveness of manual therapies: the UK evidence report," released in 2010 (http://chiromt.com/content/18/1/3). In this report, researchers found strong support for the use of manipulation (chiropractic adjustments) for the treatment of both migraine and cervicogenic-type (headaches that start in the neck) headaches. In this day and age, you can be very confident that choosing chiropractic services for headache treatment is a wise, safe, and very cost-effective approach for a very disabling condition.


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Ascomp w/Codeine (Oral)
Generic name: butalbital, aspirin, caffeine, and codeine [ bue-TAL-bi-tal, AS-pir-in, KAF-een, KOE-deen-FOS-fate ]
Brand names: Ascomp w/Codeine, Fiorinal w/Codeine
Drug class: Narcotic analgesic combinations
Medically reviewed by Drugs.com. Last updated on Sep 15, 2023.
Addiction, Abuse, and Misuse:
Butalbital/aspirin/caffeine/codeine phosphate exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient's risk prior to prescribing codeine sulfate, and monitor all patients regularly for the development of these behaviors or conditions.
Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS):To ensure that the benefits of opioid analgesics outweigh the risks of addiction, abuse, and misuse, the Food and Drug Administration (FDA) has required a REMS for these products. Under the requirements of the REMS, drug companies with approved opioid analgesic products must make REMS-compliant education programs available to healthcare providers. Healthcare providers are strongly encouraged to complete a REMS-compliant education program, counsel patients and/or their caregivers, with every prescription, on safe use, serious risks, storage, and disposal of these products, emphasize to patients and their caregivers the importance of reading the Medication Guide every time it is provided by their pharmacist, and consider other tools to improve patient, household, and community safety.
Life-Threatening Respiratory Depression:
Serious, life-threatening, or fatal respiratory depression may occur with use of butalbital/aspirin/caffeine/codeine phosphate. Monitor for respiratory depression, especially during initiation of butalbital/aspirin/caffeine/codeine phosphate or following a dose increase.
Accidental Ingestion:
Accidental ingestion of even one dose of butalbital/aspirin/caffeine/codeine phosphate, especially by children, can result in a fatal overdose of butalbital/aspirin/caffeine/codeine phosphate.
Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants:
Concomitant use of opioids with benzodiazepines or other CNS depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing of butalbital/aspirin/caffeine/codeine phosphate and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. Follow patients for signs and symptoms of respiratory depression and sedation.
Ultra-Rapid Metabolism of Codeine and Other Risk Factors for Life-Threatening Respiratory Depression in Children:
Life-threatening respiratory depression and death have occurred in children who received codeine. Most of the reported cases occurred following tonsillectomy and/or adenoidectomy, and many of the children had evidence of being an ultra-rapid metabolizer of codeine due to a CYP2D6 polymorphism. Butalbital/aspirin/caffeine/codeine phosphate is contraindicated in children younger than 12 years of age and in children younger than 18 years of age following tonsillectomy and/or adenoidectomy. Avoid the use of butalbital/aspirin/caffeine/codeine phosphate in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of codeine
Neonatal Opioid Withdrawal Syndrome:
Prolonged use of butalbital/aspirin/caffeine/codeine phosphate during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available.
Interactions with Drug Affecting Cytochrome P450 Isoenzymes:
The effects of concomitant use or discontinuation of CYP3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are complex. Use of CYP3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with butalbital/aspirin/caffeine/codeine phosphate requires careful consideration of the effects on the parent drug, codeine, and the active metabolite, morphine .
Uses for Ascomp w/Codeine
Butalbital, aspirin, caffeine, and codeine combination is used to relieve symptoms of tension (or muscle contraction) headaches. Extended and repeated use of this product is not recommended.
Butalbital belongs to the group of medicines called barbiturates. Barbiturates act in the central nervous system (CNS) to produce their effects.
Aspirin is used to relieve pain and reduce fever in patients. It belongs to the group of medicines known as salicylates and acts on the immune system to reduce inflammation. It is also known as an anti-inflammatory analgesic.
Caffeine is a CNS stimulant that is used with pain relievers to increase their effect. It has also been used for migraine headaches. Codeine belongs to the group of medicine called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.
When butalbital or codeine is used for a long time or in large doses, it may become habit-forming, causing mental or physical dependence. Physical dependence may lead to withdrawal side effects when you suddenly stop taking the medicine. In patients who get headaches, the first symptom of withdrawal may be new (rebound) headaches.
This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.
Before using Ascomp w/Codeine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of butalbital, aspirin, caffeine, and codeine combination in the pediatric population. It should not be used in children younger than 12 years of age. Safety and efficacy have not been established.
Fiorinal® with codeine should not be used to relieve pain after surgery removal of tonsils or adenoids in any children. Severe breathing problems and deaths have been reported in some children who received codeine after tonsil or adenoid surgery.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of butalbital, aspirin, caffeine, and codeine combination in the elderly. However, elderly patients are more likely to have age-related lung, liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Breast Feeding
Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Abrocitinib
- Defibrotide
- Dichlorphenamide
- Furazolidone
- Influenza Virus Vaccine, Live
- Iproniazid
- Isocarboxazid
- Ketorolac
- Linezolid
- Methylene Blue
- Moclobemide
- Nalmefene
- Naltrexone
- Nialamide
- Ozanimod
- Phenelzine
- Procarbazine
- Rasagiline
- Riociguat
- Safinamide
- Samidorphan
- Selegiline
- Toloxatone
- Tranylcypromine
- Viloxazine
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abametapir
- Abiraterone Acetate
- Acarbose
- Aceclofenac
- Acemetacin
- Acenocoumarol
- Acepromazine
- Acetazolamide
- Aclidinium
- Alclometasone
- Aldosterone
- Alfentanil
- Alipogene Tiparvovec
- Almotriptan
- Alosetron
- Alprazolam
- Alteplase, Recombinant
- Amantadine
- Amcinonide
- Amifampridine
- Amikacin
- Amiloride
- Amineptine
- Amiodarone
- Amitriptyline
- Amitriptylinoxide
- Amobarbital
- Amoxapine
- Amphetamine
- Amphotericin B
- Amprenavir
- Amtolmetin Guacil
- Anagrelide
- Anileridine
- Anisindione
- Apalutamide
- Apixaban
- Aprepitant
- Aprobarbital
- Ardeparin
- Argatroban
- Aripiprazole
- Aripiprazole Lauroxil
- Armodafinil
- Asenapine
- Atazanavir
- Atropine
- Bacitracin
- Baclofen
- Barbital
- Beclomethasone
- Belladonna
- Bemetizide
- Bemiparin
- Benazepril
- Bendroflumethiazide
- Benperidol
- Bentazepam
- Benzhydrocodone
- Benzphetamine
- Benzthiazide
- Benztropine
- Betamethasone
- Betrixaban
- Biperiden
- Bivalirudin
- Boceprevir
- Bosentan
- Brinzolamide
- Bromazepam
- Bromfenac
- Bromopride
- Brompheniramine
- Budesonide
- Bufexamac
- Bumetanide
- Buprenorphine
- Bupropion
- Buspirone
- Butabarbital
- Butorphanol
- Calcium Oxybate
- Cannabidiol
- Cannabis
- Canrenoate
- Canrenone
- Caplacizumab-yhdp
- Capmatinib
- Capreomycin
- Captopril
- Carbamazepine
- Carbinoxamine
- Carisoprodol
- Carphenazine
- Celecoxib
- Cenobamate
- Certoparin
- Cetirizine
- Chloral Hydrate
- Chlordiazepoxide
- Chlorothiazide
- Chlorpheniramine
- Chlorpromazine
- Chlorpropamide
- Chlorthalidone
- Chlorzoxazone
- Choline Salicylate
- Ciclesonide
- Cilostazol
- Cimetidine
- Cinacalcet
- Ciprofloxacin
- Cisplatin
- Citalopram
- Clarithromycin
- Clemastine
- Clidinium
- Clobazam
- Clobetasol
- Clobetasone
- Clocortolone
- Clomipramine
- Clonazepam
- Clonixin
- Clopamide
- Clopidogrel
- Clorazepate
- Cloxazolam
- Clozapine
- Cobicistat
- Cocaine
- Conivaptan
- Cortisone
- Crizotinib
- Curcumin
- Cyclobenzaprine
- Cyclopenthiazide
- Cyclopentolate
- Cyclosporine
- Cyclothiazide
- Cyproheptadine
- Dabigatran Etexilate
- Dalteparin
- Danaparoid
- Dantrolene
- Daridorexant
- Darifenacin
- Darunavir
- Deflazacort
- Delavirdine
- Delorazepam
- Desipramine
- Desirudin
- Desmopressin
- Desonide
- Desoximetasone
- Desvenlafaxine
- Dexamethasone
- Dexibuprofen
- Dexketoprofen
- Dexmedetomidine
- Dextroamphetamine
- Dextromethorphan
- Dezocine
- Diacetylmorphine
- Diazepam
- Diazoxide
- Dibenzepin
- Dichloralphenazone
- Diclofenac
- Dicumarol
- Dicyclomine
- Difenoxin
- Diflorasone
- Diflucortolone
- Diflunisal
- Difluprednate
- Digoxin
- Dihydrocodeine
- Diltiazem
- Dimenhydrinate
- Diphenhydramine
- Diphenoxylate
- Dipyrone
- Dolasetron
- Donepezil
- Dorzolamide
- Dothiepin
- Doxepin
- Doxorubicin
- Doxorubicin Hydrochloride Liposome
- Doxylamine
- Dronedarone
- Droperidol
- Drospirenone
- Droxicam
- Duloxetine
- Edoxaban
- Efavirenz
- Elagolix
- Eletriptan
- Emtricitabine
- Enalapril
- Enalaprilat
- Enflurane
- Enoxaparin
- Enzalutamide
- Eplerenone
- Eptifibatide
- Erythromycin
- Escitalopram
- Esketamine
- Eslicarbazepine Acetate
- Estazolam
- Eszopiclone
- Eterobarb
- Ethacrynic Acid
- Ethchlorvynol
- Ethinyl Estradiol
- Ethopropazine
- Ethylmorphine
- Etodolac
- Etofenamate
- Etonogestrel
- Etoricoxib
- Etozolin
- Etravirine
- Fedratinib
- Felbinac
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- Fluticasone
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- Fosamprenavir
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- Foscarnet
- Fosinopril
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- Gabapentin Enacarbil
- Gentamicin
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- Iobenguane I 131
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- Isoflurane
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- Ivacaftor
- Kanamycin
- Ketamine
- Ketazolam
- Ketobemidone
- Ketoconazole
- Ketoprofen
- Lacosamide
- Larotrectinib
- Lasmiditan
- Lemborexant
- Lenacapavir
- Lepirudin
- Letermovir
- Levocetirizine
- Levomilnacipran
- Levorphanol
- Linezolid
- Lisdexamfetamine
- Lisinopril
- Lithium
- Lofepramine
- Lofexidine
- Lomitapide
- Lopinavir
- Loprazolam
- Lorazepam
- Lorcaserin
- Lorlatinib
- Lormetazepam
- Lornoxicam
- Loteprednol
- Loxapine
- Loxoprofen
- Lumacaftor
- Lumiracoxib
- Macimorelin
- Magnesium Oxybate
- Mavacamten
- Meclizine
- Meclofenamate
- Medazepam
- Medrysone
- Mefenamic Acid
- Melitracen
- Meloxicam
- Melperone
- Melphalan
- Mepenzolate
- Meperidine
- Mephenesin
- Mephobarbital
- Meprobamate
- Meptazinol
- Mesoridazine
- Metaclazepam
- Metaxalone
- Metformin
- Methadone
- Methamphetamine
- Methazolamide
- Methdilazine
- Methocarbamol
- Methohexital
- Methotrexate
- Methotrimeprazine
- Methyclothiazide
- Methylene Blue
- Methylprednisolone
- Metoclopramide
- Metolazone
- Mibefradil
- Midazolam
- Mifepristone
- Milnacipran
- Mirabegron
- Mirtazapine
- Mitotane
- Modafinil
- Moexipril
- Molindone
- Mometasone
- Moricizine
- Morniflumate
- Morphine
- Morphine Sulfate Liposome
- Nabumetone
- Nadroparin
- Nafcillin
- Nalbuphine
- Naproxen
- Naratriptan
- Nateglinide
- Nefazodone
- Nelfinavir
- Neomycin
- Nepafenac
- Netilmicin
- Netupitant
- Nevirapine
- Nicomorphine
- Nicorandil
- Nifedipine
- Niflumic Acid
- Nilotinib
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Nitrazepam
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- Nordazepam
- Norethindrone
- Norgestimate
- Norgestrel
- Nortriptyline
- Olanzapine
- Omaveloxolone
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- Opipramol
- Opium
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- Phenelzine
- Phenindione
- Phenobarbital
- Phenprocoumon
- Phenylbutazone
- Phenytoin
- Piketoprofen
- Pinazepam
- Pipenzolate Bromide
- Piperacetazine
- Piperaquine
- Pipotiazine
- Piracetam
- Pirenzepine
- Piretanide
- Piritramide
- Piroxicam
- Pixantrone
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- Polythiazide
- Posaconazole
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- Potassium Oxybate
- Pranoprofen
- Prasugrel
- Prazepam
- Prednicarbate
- Prednisolone
- Prednisone
- Pregabalin
- Primidone
- Procarbazine
- Prochlorperazine
- Procyclidine
- Proglumetacin
- Promazine
- Promethazine
- Propantheline
- Propiverine
- Propofol
- Propyphenazone
- Proquazone
- Protein C
- Protriptyline
- Quazepam
- Quetiapine
- Quinapril
- Quinethazone
- Quinidine
- Quinine
- Ramelteon
- Ramipril
- Ranitidine
- Ranolazine
- Rasagiline
- Remifentanil
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- Remoxipride
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- Solifenacin
- Spectinomycin
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- Triazolam
- Trichlormethiazide
- Trifluoperazine
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- Triflupromazine
- Trihexyphenidyl
- Trimeprazine
- Trimipramine
- Tropicamide
- Trospium
- Tryptophan
- Turmeric
- Ulipristal
- Umeclidinium
- Valdecoxib
- Valproic Acid
- Vancomycin
- Varicella Virus Vaccine, Live
- Venlafaxine
- Verapamil
- Vilazodone
- Voriconazole
- Vortioxetine
- Voxelotor
- Warfarin
- Xipamide
- Zaleplon
- Ziprasidone
- Zolmitriptan
- Zolpidem
- Zopiclone
- Zotepine
- Zuranolone
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acebutolol
- Atenolol
- Betaxolol
- Bisoprolol
- Carteolol
- Carvedilol
- Celiprolol
- Delapril
- Esmolol
- Imidapril
- Labetalol
- Levobunolol
- Metipranolol
- Metoprolol
- Nadolol
- Nebivolol
- Nitroglycerin
- Ospemifene
- Oxprenolol
- Penbutolol
- Pindolol
- Prednisone
- Probenecid
- Propranolol
- Sotalol
- St John's Wort
- Streptokinase
- Tamarind
- Temocapril
- Tenecteplase
- Timolol
- Warfarin
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
- Ethanol
- Tobacco
Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
- Ethanol
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Addison's disease (an adrenal problem) or
- Alcohol abuse, or history of or
- Brain tumor, history of or
- Breathing problems (eg, COPD, hypercapnia, hypoxia, sleep apnea) or
- Cor pulmonale (serious heart condition) or
- Depression, or history of or
- Drug dependence, especially with narcotic abuse or dependence, or history of or
- Enlarged prostate or
- Head injury, or history of or
- Hypothyroidism (underactive thyroid) or
- Increased pressure in the head or
- Obesity (overweight) or
- Stomach or digestion problems or
- Trouble urinating or
- Weakened physical condition—Use with caution. May increase risk for more serious side effects.
- Asthma with nasal polyps and rhinitis, history of or
- Hemophilia (bleeding problem) or
- Hypoprothrombinemia (low prothrombin in the blood) or
- Liver damage, severe or
- Lung or breathing problems (eg, asthma, respiratory depression), severe or
- Porphyria (enzyme problem) or
- Reye's syndrome or
- Stomach or bowel problems (eg, paralytic ileus, peptic ulcer, lesions) or
- Surgery (eg, nasopharyngeal tonsils, tonsils) or
- Thrombasthenia (a platelet disorder) or
- Thrombocytopenia (low platelets in the blood) or
- Vitamin K deficiency or
- von Willebrand's disease (blood clotting disorder)—Should not be used in patients with these conditions.
- Chicken pox or
- Flu—Use with caution. May increase risk of having a condition called Reye's syndrome.
- Gallbladder problems or
- Hypotension (low blood pressure) or
- Pancreatitis (swelling of the pancreas) or
- Seizures, history of or—Use with caution. May make these conditions worse.
- Kidney disease or
- Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Related/similar drugs
acetaminophen, ibuprofen, amitriptyline, diclofenac, naproxen, Tylenol
Proper use of Ascomp w/Codeine
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming and cause mental or physical dependence.
It is very important that you understand the rules of the Opioid Analgesic REMS program to prevent addiction, abuse, and misuse of butalbital, aspirin, caffeine, and codeine combination. This medicine should also come with a Medication Guide. Read and follow these instructions carefully. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions.
Drink plenty of fluids to help avoid constipation.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (capsules):
- For tension headaches:
- Adults—1 or 2 capsules every 4 hours as needed. Do not take more than 6 capsules per day.
- Children 12 years of age and older—Use and dose must be determined by your doctor.
- Children younger than 12 years of age—Should not be used in these patients.
- For tension headaches:
Missed Dose
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm .
Precautions while using Ascomp w/Codeine
It is very important that your doctor check your or your child's progress while using this medicine, especially within the first 24 to 72 hours of treatment. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood and urine tests may be needed to check for unwanted effects.
Do not use this medicine if you are using or have used an MAO inhibitor (MAOI) such as isocarboxazid [Marplan®], linezolid [Zyvox®], phenelzine [Nardil®], selegiline [Eldepryl®], tranylcypromine [Parnate®]) within the past 14 days.
Do not change your dose or suddenly stop using this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, including stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.
Using this medicine while you are pregnant, especially during the later part of pregnancy may cause serious unwanted effects, including neonatal withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.
Codeine is changed to morphine in the body. Some people change codeine to morphine more quickly than others. These individuals are called "ultra-rapid metabolizers of codeine". Contact your doctor immediately if you experience extreme sleepiness, confusion, or shallow breathing. These symptoms may indicate that you are an "ultra-rapid metabolizer of codeine". As a result, there is too much morphine in the body and more side effects of morphine than usual. Children may be especially sensitive to this effect. Do not give this medicine to:
- Children younger than 12 years of age.
- Children younger than 18 years of age who have had surgery removal of tonsils or adenoids.
- Children 12 to 18 years of age who have a high risk for breathing problems (eg, obstructive sleep apnea, obesity, lung disease).
If a nursing mother is an ultra-rapid metabolizer of codeine, it could lead to a morphine overdose in the nursing baby and cause very serious side effects.
For nursing mothers using this medicine:
- Talk to your doctor if you have any questions about using codeine or about how this medicine may affect your baby.
- Call your doctor if you become extremely tired and have difficulty caring for your baby.
- Your baby should generally nurse every 2 to 3 hours and should not sleep for more than 4 hours at a time.
- Check with your doctor or hospital emergency room right away if your baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, difficulty breathing, or limpness. These may be symptoms of an overdose and need immediate medical attention.
Aspirin may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash, hives, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
This medicine may cause adrenal gland problems. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.
Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help. Also, lying down for a while may relieve dizziness or lightheadedness. If this problem continues or gets worse, check with your doctor right away.
This medicine may cause bleeding in your stomach or intestines. This problem can happen without warning signs. This is more likely if you have had a stomach ulcer in the past, if you smoke or drink alcohol regularly, if you are over 60 years of age, are in poor health, or are using certain other medicines (eg, steroids or a blood thinner).
This medicine may make you dizzy, drowsy, confused, or disoriented. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Check with your doctor right away if you have black, tarry stools, chest pain, chills, cough, fever, painful or difficult urination, sore throat, sores, ulcers, or white spots on the lips or in the mouth, swollen glands, trouble breathing, unusual bleeding or bruising, or unusual tiredness or weakness. These may be symptoms of serious skin reaction including drug reaction with eosinophilia and systemic symptoms (DRESS).
This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine.
If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Your doctor may also give naloxone to treat an overdose. Signs of an overdose include: cold, clammy skin, coughing that sometimes produces a pink frothy sputum, seizures, difficult or trouble breathing, irregular, fast or slow, or shallow breathing, nausea or vomiting, pain in the upper stomach, pale or blue lips, fingernails, or skin, pinpoint pupils of the eyes, swelling in the legs and ankles, or trouble sleeping.
Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.
Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.
Check with your doctor right away if you or your child have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body.
Using too much of this medicine may cause infertility (unable to have children) or may cause a delay in ovulation for women and may affect their ability to have children. Talk with your doctor before using this medicine if you plan to have children.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects of Ascomp w/Codeine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
- Back, leg, or stomach pains
- black, tarry stools
- bleeding gums
- blistering, peeling, or loosening of the skin
- bloody urine
- blurred vision
- chest pain or tightness
- chills
- confusion
- cough
- dark urine
- decreased frequency or amount of urine
- diarrhea
- difficulty breathing
- difficulty swallowing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast, irregular, pounding, or racing heartbeat or pulse
- fever
- general tiredness and weakness
- headache
- hives, itching, or skin rash
- increased thirst
- joint or muscle pain
- light-colored stools
- lower back or side pain
- nausea
- nosebleeds
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red skin lesions, often with a purple center
- red, irritated eyes
- shakiness in the legs, arms, hands, or feet
- sores, ulcers, or white spots in the mouth or on the lips
- sweating
- swelling of the face, fingers, or lower legs
- trembling or shaking of the hands or feet
- upper right abdominal or stomach pain
- vomiting
- vomiting blood
- weight gain
- yellow eyes and skin
Incidence not known
- Agitation
- bloody nose
- confusion
- constricted, pinpoint, or small pupils (black part of the eye)
- darkening of the skin
- loss of appetite
- mental depression
- overactive reflexes
- poor coordination
- restlessness
- seeing, hearing, or feeling things that are not there
- shivering
- trouble sleeping
- twitching
- unusual tiredness or weakness
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
- Cold and clammy skin
- confusion as to time, place, or person
- continuing ringing or buzzing or other unexplained noise in the ears
- coughing that sometimes produces a pink frothy sputum
- difficult or trouble breathing
- drowsiness
- extremely high fever or body temperature
- hearing loss
- holding false beliefs that cannot be changed by fact
- increased sweating
- irregular, fast or slow, or shallow breathing
- loss of consciousness
- muscle cramps
- pale or blue lips, fingernails, or skin
- pinpoint pupils (black part of the eyes)
- restlessness
- seeing, hearing, or feeling things that are not there
- seizures
- swelling in the legs and ankles
- trouble sleeping
- unusual bleeding or bruising
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Anxiety
- blurred vision
- burning, tingling, numbness, or pain in the hands, arms, feet, or legs
- confusion about identity, place, and time
- constricted, pinpoint, or small pupils (black part of the eye)
- deep or fast breathing with dizziness
- depression
- difficulty having a bowel movement
- dry mouth
- feeling of constant movement of self or surroundings
- feeling of warmth
- feeling that others are watching you or controlling your behavior
- feeling that others can hear your thoughts
- heartburn
- high energy
- irregular heartbeat
- irritability
- loss in sexual ability, desire, drive, or performance
- numbness of the feet, hands, and around mouth
- pain in the legs
- redness of the face, neck, arms, and occasionally, upper chest
- sensation of spinning
- severe mood or mental changes
- shaking
- sleepiness
- sluggishness
- slurred speech
- trouble sitting still
- unexplained weight loss
- unusual behavior
- weakness
Incidence not known
- Decreased interest in sexual intercourse
- inability to have or keep an erection
- loss in sexual ability, desire, drive, or performance
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Commonly used brand name(s)
In the U.S.
- Ascomp w/Codeine
- Fiorinal w/Codeine
In Canada
- Fiorinal-C 1/2
- Fiorinal-C 1/4
- Teva-Tecnal C1/2
- Teva-Tecnal C1/4
- Trianal C1/2
- Trianal C1/4
Available Dosage Forms:
- Capsule
Therapeutic Class: Opioid/Barbiturate Combination
Pharmacologic Class: Barbiturate
Chemical Class: Salicylate, Aspirin
More about aspirin / butalbital / caffeine / codeine
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (35)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: narcotic analgesic combinations
- En español
Patient resources
- Aspirin, butalbital, caffeine, and codeine drug information
- Butalbital, aspirin, caffeine, and codeine (Advanced Reading)
- Butalbital, Aspirin, Caffeine, and Codeine
Other brands
Ascomp with Codeine, Fiorinal with Codeine, Fiorinal with Codeine III
Professional resources
Other brands
Ascomp with Codeine, Fiorinal with Codeine
Related treatment guides
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.


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35 Best DIY Pink Living Room Decor Ideas For Teens Girls – Page 11 – Chic Cuties Blog
Your little daughter wants a new bedroom? How about renovating the old or just filling it with new furniture sets? It sounds so easy. However, it can be difficult to find the theme of the new design and choose the right beds, tables, cardboards, etc. Let's start with a few tips to help you choose a new design easily and effectively.
Talk to your child: you may already have known a lot about your favorite books, cartoons and bands. However, you cannot be sure how she imagines her bedroom. You shouldn't consider all of your ideas. Some of them may even give birth to their daughter after several weeks. Listen to ideas that match both the style of your home and the amount of money on your credit card.
Make a plan: create a board with your favorite furniture sets for girls in different styles. Analyze which design is best for your space. Read the reviews about the furniture you like. Try to imagine what problems you might encounter with this design in the future.
Go shopping: After you have created the list of furniture sets for girls that you like the most, find them. Visit different shops. Do not hesitate to ask about anything you want to know. Find out what guarantees the manufacturer offers. Think about which colors best suit your new design. Don't forget the quality of the furniture.
[gallery columns="2" size="full" ids="48391,48392,48393,,,48394,48395,48396,48397,48398,48399,48400"]


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Bernard Ollis (born 1951 in Bath, England) is an Australian artist and painter who lives and works in Sydney and Paris. Ollis is the former Director of the National Art School, Sydney. Ollis is a graduate of Cardiff School of Art & Design, Wales and received his Master of Art (Painting) from the Royal College of Art. Ollis arrived in Australia in 1976 and lectured at the University of the Northern Territory where he became head of his department, and La Trobe University, Victoria where he became Head of Fine Art. In 1996, Ollis was appointed Head of Painting at the National Art School, Sydney. He became Director there in late 1997, a position he held for 10 years.
Bernard Ollis 'Fascinating Places' Exhibition 2024
Bernard Ollis 'An Opulent World' Exhibition 2022
Affordable Art Fair Sydney 2022
Grand Seaforth Reopening Exhibition 2022
Bernard Ollis 'From the Studio' Under 5K Online Exhibition 2021
Bernard Ollis 'The Artists Garden Part 2' Mosman Exhibition 2021
Bernard Ollis 'The Artists Garden Part 1' Mosman Exhibition 2020
Bernard Ollis 'Being There' Mosman Exhibition 2018
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Free Collection
For all fine art purchases, free collection is available from our Gallery in Seaforth. For Art of Dr. Seuss purchases, free collection is available from QVB (Sydney) or The Block (Melbourne).
International Shipping
For international shipping, please contact us for a quote.
All online orders will be processed within 48 hours (business days), unless the artwork is a part of a current exhibition or is an Art of Dr. Seuss purchase.
Exhibition artwork will be shipped once the exhibition closes and for an Art of Dr. Seuss purchase, please allow 14 – 16 weeks for delivery from date of purchase.
The average time for dispatch for all other artworks is approximately 5 business days, depending on availability and payment arrangements.
Delivery will take between 5 – 10 business days Australia wide.
We will confirm your order and dispatch arrangement details by email or phone.
All Prices are in AUD (Australian currency)
You can purchase online using a Credit Card, Art Money, Paypal, or Bank Transfer.
Our website is secured using an SSL certificate to make sure your information is safe. We also use secure payment methods. If you you'd prefer to speak to one of our team, or if you have any questions, please refer to our contact us page.
Oil on Board
48.5 x 35.5 cm Framed
A$2,700 Buy NowOil on Linen
53.5 x 44 cm Framed
A$3,600 Buy NowOil on Canvas
34 x 51 cm Framed
A$3,200 Buy NowOil on Linen
38 x 38.5 cm Framed
A$2,000 Buy NowHarvey Galleries was founded by the Harvey family in 1994 with an eye to establish a dynamic and inclusive contemporary art space on the North Shore of Sydney. For almost three decades we have expanded our reach to over three gallery locations and an ever expanding stable of the best artists Australia has to offer.
Harvey Galleries acknowledges the traditional custodians of the lands upon which our galleries stand. The Guringai people (Seaforth), the Gadigal people of the Eora Nation (Sydney), and the Bunurong Boon Wurrung and Wurundjeri Woi Wurrung peoples of the Eastern Kulin Nation (Melbourne).
We pay our respect to Elders past and present.
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