text:
Honey bee venom toxins trigger immunological, physiological
and neurological responses within victims. The high occurrence of bee attacks
involving potentially fatal toxic and allergic reactions in humans and the
prospect of developing novel pharmaceuticals make honey bee venom an attractive
target for proteomic studies. Using label-free quantification, we compared the
proteome and phosphoproteome of the venom of Africanized honeybees with that of
two European subspecies, namely A. m. ligustica and A. m. carnica. From the
total of 51 proteins, 42 were common to all three subspecies. Remarkably, the
toxins melittin and icarapin were phosphorylated. In all venoms, icarapin was
phosphorylated at the 205 Ser residue, which is located in close proximity to
its known antigenic site. Melittin, the major toxin of honeybee venoms, was
phosphorylated in all venoms at the 10 Thr and 18 Ser residues. 18 Ser
phosphorylated melittin - the major of its two phosphorylated forms -was less
toxic compared to the native peptide.
Sunday, June 30, 2013
Proteome and Phosphoproteome of Africanized and European Honeybee Venoms
Proteomics, 2013 Jun 25
Bee Venom
Saturday, June 29, 2013
Eating Drone Larvae Suppresses Blood Glucose, Cholesterol
Br Poult Sci, 2013 Jun;54(3):355-361
1. An experiment was conducted to determine the possibility
of stimulating sexual development at an early age in male and female broiler
chickens by administration of apilarnil, a natural bee product, in the
pre-pubertal period.
2. From 28 to 55 d of age, birds were given apilarnil
orally. The effects of low (2.5 g/bird) and high (7.5 g/bird) doses of
apilarnil on growth performance, testicular weight, secondary sexual
characteristics, blood lipids, testosterone and fearful behaviour were
3. Apilarnil administration did not cause a positive effect
on growth performance of male and female broilers suggesting that apilarnil did
not have an anabolic effect.
4. Apilarnil administration suppressed blood glucose and
5. Birds receiving apilarnil remained immobile for a shorter
period in a tonic immobility test and showed less home-cage avoidance responses
suggesting a lower level of fearfulness.
6. Increases in testicular weight, testosterone
concentration and comb growth in males receiving apilarnil implied that it
stimulates the sexual maturation at an early age. However, a similar
stimulation of secondary sexual characteristics was not observed in females.
Apitherapy and Beekeeping
Friday, June 28, 2013
Saudis Use Honey Bee Products as Complementary and Alternative Medicine
The use of and out-of-pocket spending on complementary and
alternative medicine in Qassim province, Saudi Arabia
Ann Saudi Med, 2013 MAY-JUNE;33(3):282-289.
The current picture of the Saudis' use of complementary and
alternative medicine (CAM) has not yet been developed. The aim of this study
was to assess the feasibility of using the international questionnaire to
measure use of complementary and alternative medicine (I-CAM-Q) in Saudi Arabia
to evaluate the use of and out-of-pocket spending on CAM.
It was a cross-sectional study, conducted in 2011, in
primary health care centers in Qassim.
In a multistage sampling technique, 12 primary health care
centers were selected randomly in the Al-Qassim province in Saudi Arabia. From
each center, 100 attendants were interviewed for a total of 1160 completed
A total of 74% of subjects had visited CAM providers in 12
months before the survey. This percentage decreased to 47.6% when spiritual
healers were excluded. The specific CAM providers who were visited were
spiritual healers (26.7%), herbalists (23.2%), providers of honeybee products
(14.9%), and hijama (wet cupping; 13%). Chronic illnesses were the main reason
for the visits. A total of 50% of subjects were satisfied with their visit.
Physicians were the providers of CAM for 11.3% of the participants. More than
75% of the subjects used herbs in the previous 12 months for medical and health
reasons, while only 25% used vitamins or minerals. Self-help was used in 26% of
the participants. Relaxation (10.3%) was the most common self-CAM practice
followed by meditation (6.7%). The subjects spent 350000 (US$) on CAM visits
and 300000 (US$) purchasing CAM products.
I-CAM-Q can be used in different populations and cultures in
the East including Saudi Arabia after customization to overcome its
limitations, as the questionnaire was developed in Western societies.
Bee Venom,
Bee-Collected Pollen,
Royal Jelly
Thursday, June 27, 2013
Letter: Topical Honey for Diabetic Foot Ulcers
Dtsch Arztebl Int 2013; 110(21): 373
Local Treatment of Chronic Wounds in Patients With
Peripheral Vascular Disease, Chronic Venous Insufficiency and Diabetes by Dr.
med. Mike Rüttermann, Dr. med. Andreas Maier-Hasselmann, Brigitte Nink-Grebe,
Marion Burckhardt in volume 3/2013
The data regarding different treatments for wounds are still
disappointingly scant. No grade B recommendations are available for wound care
products, and grade A seems completely out of the question! A grade B
recommendation exists only in favor of hydrogel, hyperbaric oxygenation in
ulcers that are beyond treatment in diabetic foot syndrome, and integrated
care. In view of the many patients and the vast market in wound care products,
this is sobering. I was therefore all the more surprised at the recommendation
not to use honey for chronic wounds (the context was really generally that of
chronic wounds) because honey resulted in more pain in a single study of venous
ulcers. Why was a special scenario (venous ulcers) generalized to include all
chronic wounds?
Years of experience with manuka honey in patients with
diabetic foot syndrome have shown that pain usually does not constitute a
problem in these wounds owing to the comorbid polyneuropathy. I would have
welcomed a fact-based recommendation, differentiated by evidence level (which
exists for a negative recommendation only for venous ulcers). Numerous small,
qualitatively moderate to poor studies of honey treatment in diabetic foot
syndrome have shown mostly promising results, which are entirely consistent
with my own observations. Obviously, high-quality randomized controlled studies
of honey treatment in diabetic foot syndrome are absolutely necessary and
desirable. But until these have been conducted and reported, the treatment of
the diabetic foot syndrome with honey provides an efficient, cost-effective
variant with a poor evidence base. This, however, is also the case for all
other wound treatments.
Wednesday, June 26, 2013
Propolis May Help Treat Hypertension
Propolis Reduces Oxidative Stress in l-NAME-Induced
Hypertension Rats
Cell Biochemistry and Function, Early View
The inhibition in the synthesis or bioavailability of nitric
oxide (NO) has an important role in progress of hypertension. The blocking of
nitric oxide synthase activity may cause vasoconstriction with the formation of
reactive oxygen species (ROS). Propolis is a resinous substance collected by
honey bees from various plants. Propolis has biological and pharmacological
properties. The aim of this study was to examine the effect of propolis on
catalase (CAT) activity, malondialdehyde (MDA) and NO levels in the testis
tissues of hypertensive rats by Nω-nitro-l-arginine methyl ester (l-NAME).
Rats have received nitric oxide synthase inhibitor (l-NAME,
40 mg kg−1, intraperitoneally) for 15 days to produce hypertension and propolis
(200 mg kg−1, by gavage) during the last 5 days. MDA level in l-NAME-treated
group significantly increased compared with control group (P < 0.01). MDA
level of l-NAME + propolis-treated rats significantly reduced (P < 0.01)
compared with l-NAME-treated group. CAT activity and NO level significantly
reduced (P < 0.01) in l-NAME group compared with control group. There were
no statistically significant increases in the CAT activity and NO level of the
l-NAME + propolis group compared with the l-NAME-treated group (P > 0.01).
These results suggest that propolis changes CAT activity, NO
and MDA levels in testis of l-NAME-treated animals, and so it may modulate the
antioxidant system.
Tuesday, June 25, 2013
Novel Antimicrobial Peptides Isolated From Wild Bee Venom
Panurgines, Novel Antimicrobial Peptides from the Venom of Communal
Bee Panurgus calcaratus
Amino Acids, 2013 Jul;45(1):143-57
Three novel antimicrobial peptides (AMPs), named panurgines
(PNGs), were isolated from the venom of the wild bee Panurgus calcaratus. The
dodecapeptide of the sequence LNWGAILKHIIK-NH2 (PNG-1) belongs to the category
of α-helical amphipathic AMPs. The other two cyclic peptides containing 25
amino acid residues and two intramolecular disulfide bridges of the pattern
Cys8-Cys23 and Cys11-Cys19 have almost identical sequence established as
LDVKKIICVACKIXPNPACKKICPK-OH (X=K, PNG-K and X=R, PNG-R). All three peptides
exhibited antimicrobial activity against Gram-positive bacteria and
Gram-negative bacteria, antifungal activity, and low hemolytic activity against
human erythrocytes.
We prepared a series of PNG-1 analogs to study the effects
of cationicity, amphipathicity, and hydrophobicity on the biological activity.
Several of them exhibited improved antimicrobial potency, particularly those
with increased net positive charge. The linear analogs of PNG-K and PNG-R
having all Cys residues substituted by α-amino butyric acid were inactive, thus
indicating the importance of disulfide bridges for the antimicrobial activity.
However, the linear PNG-K with all four cysteine residues unpaired, exhibited
antimicrobial activity. PNG-1 and its analogs induced a significant leakage of
fluorescent dye entrapped in bacterial membrane-mimicking large unilamellar
vesicles as well as in vesicles mimicking eukaryotic cell membrane. On the
other hand, PNG-K and PNG-R exhibited dye-leakage activity only from vesicles
mimicking bacterial cell membrane.
Bee Venom
Monday, June 24, 2013
Antimicrobial Properties of Honey
Am J Ther, 2013 Jun 18
Honey has been widely accepted as food and medicine by all generations, traditions, and civilizations, both ancient and modern. For at least 2700 years, honey has been used by humans to treat a variety of ailments through topical application, but only recently have the antiseptic and antimicrobial properties of honey been discovered. Honey has been reported to be effective in a number of human pathologies. Clinical studies have demonstrated that application of honey to severely infected cutaneous wounds rapidly clears infection from the wound and improves tissue healing.
A large number of in vitro and limited clinical studies have confirmed the broad-spectrum antimicrobial (antibacterial, antifungal, antiviral, and antimycobacterial) properties of honey, which may be attributed to the acidity (low pH), osmotic effect, high sugar concentration, presence of bacteriostatic and bactericidal factors (hydrogen peroxide, antioxidants, lysozyme, polyphenols, phenolic acids, flavonoids, methylglyoxal, and bee peptides), and increase in cytokine release, and to immune modulating and anti-inflammatory properties of honey; the antimicrobial action involves several mechanisms. Despite a large amount of data confirming the antimicrobial activity of honey, there are no studies that support the systemic use of honey as an antibacterial agent.
Sunday, June 23, 2013
Demand for Manuka Honey Exports to Indonesia
Radio New Zealand, 6/21/2013
A Maori business consultancy firm says there's huge
potential for Maori business in Indonesia and it may be able to break through
by exporting manuka honey.
Members of the Poutama Trust recently attended a trade
mission to Jakarta.
Chief executive Richard Jones says manuka honey has taken
off in China, but so far not in Indonesia, despite high demand.
He says a large Indonesian pharmaceutical company, Kalbe
Farma, is interested in importing the product and samples of manuka honey,
energy bars, gels and lozenges were sent over this week…
Saturday, June 22, 2013
Review: Me, the Bees and Cancer
Review by Wyndham Wise, Associate Editor, Canadian MovieDatabase, 6/20/2013
(June 20, 2013 - Toronto, Ontario) John Board is veteran
Canadian 1st AD/associate producer with an impressive resume that dates back to
1970 and Paul Almond's Act of the Heart. He has worked with David Cronenberg on
seven of his films (The Brood, Videodrome, The Dead Zone, The Fly, Dead
Ringers, Naked Lunch and M. Butterfly), and his other credits include the
Oscar-nominated Atlantic City and the Genie-winning The Grey Fox.
Board is also a passionate advocate of homeopathic medicine,
and in 2002 he compiled something call he calls his 'Hollywood Survival Kit,' a
handy briefcase full of remedies, herbs and ointments, which he claims,
enthusiastically and repeatedly, has something to cure anything. In fact, Board
is so convinced the first scene in his documentary Me, the Bees and Cancer
(which opens tomorrow, June 21 at the Royal in Toronto) is devoted to a rap
song that he wrote and performs in front of his house – sort of an
advertisement in rap extoling the virtues of his 'Survival Kit.'
Two-years ago Board was diagnosed with Hodgkin's lymphoma, a
fairly common form of cancer resulting in the growth of a tumor in his right
armpit. With a grand of seed money from the $1,000 Feature Film Challenge, he
sought to document his own cancer alternative – bee sting or venom therapy. The
result is an intensely personal and at times hard-to-watch documentary…
Bee Venom
Friday, June 21, 2013
Video: Report on Medicinal Benefits of Bee Products – Honey, Propolis, Venom, Royal Jelly
Honey has been used as a medicine since time immemorial; as a remedy for digestive problems, bad circulation, breathing difficulties and – of course – as the ultimate elixir for a sore throat.
But honey is also an effective antiseptic and antibiotic, with the power to ward off wound infections, reduce inflammation and promote healing.
The medicinal molten gold includes germ-killing inhibins, which slow down the production of bacteria, and the protein defensin-1, which helps stimulates the immune system.
Besides honey, bees also produce other useful substances, such as propolis. This is a yellow, waxy resin bees use to seal the cells in their hive. They collect it from the sap of trees, and when these trees have strong antibiotic properties – as the poplar, willow and birch do – the propolis transfers these antibiotic benefits to the hive, and thus to the honey itself.
As Professor Henri Joyeux explains, the uses of propolis are endless: "We realized that propolis could have had antiseptic effects, as an antibiotic or anti-inflammatory. And when the bees leave the hive, we will are able to extract it, and purify it. This purification is such that one can produce a small alcoholic extract, which can help, because it is quite thick, fat, and contains considerable vitamins, minerals, and has a very interesting effect on bronchoalveolar respiration. For example, if you have a child suffering from a little asthma, you put 5 drops of propolis in his breakfast, you mix it, and it'll solve the problem immediately."
Bee therapy's most prized product, however, is still royal jelly; a concentrated honey made exclusively for queen bees...
Bee Venom,
Royal Jelly
Thursday, June 20, 2013
Major Royal Jelly Protein Exists Mainly as Apisin in Royal Jelly
Quantification of Major Royal Jelly Protein 1 in Fresh Royal
Jelly by Indirect Enzyme-Linked Immunosorbent Assay
Biosci Biotechnol Biochem, 2013 Jun 7
Rabbit polyclonal antibody produced by a major royal jelly
protein 1 (MRJP1) specific peptide reacted only with a MRJP1. Indirect ELISA
with the antibody revealed a MRJP1 level of 4.12-4.67 g/100 g in different
company's royal jelly, which almost agreed with that of a hexametric form of
MRJP1 (apisin) measured by high performance liquid chromatography. These
results suggest that MRJP1 exists mainly as apisin in royal jelly.
Royal Jelly
Wednesday, June 19, 2013
First Case of Folliculitis Associated with Granuloma as a Complication of Bee Sting Acupuncture
Granulomatous Inflammation with Chronic Folliculitis as a Complication
of Bee Sting Acupuncture
Indian J Dermatol Venereol Leprol, 2013 Jul-Aug;79(4):554
Bee sting therapy is one of the traditional herbal medical
procedures that has been widely used for the treatment of chronic recalcitrant
neuralgia and arthralgia in Asian and Middle Eastern countries, and is also
called apitherapy. There are two methods of this therapy, one is stinging
directly to the treatment site [Figure 1] and the other is injecting the
artificially extracted venom from a bee. The substrates that compose the venom
of a bee have anti-inflammatory and analgesic effect. The bee leaves poison sac
and neural plexus when stinging, and the retained sting materials at the
treatment site may induce inflammation and granulomatous reaction.
A 50-year-old man visited our clinic complaining of
erythematous papules and nodules with tingling sensation on his back [Figure 2]
which showed wax and wane for the past 3 months, despite he had been treated
with intralesional injection of steroid in a private clinic. He had no specific
history but received bee sting acupuncture for several years in an oriental
medical clinic due to his back pain. The skin lesions occurred after 2-3 years
from the apitherapy procedures, directly at the sites that received the
acupuncture. Histopathologic findings of biopsy specimen taken from the back
showed perifollicular dense inflammatory infiltration composed of lymphocytes,
plasma cells, and histiocytes [Figure 3]a and b. Around the perifollicular
infiltration, ruptured granulomatous reaction composed of epitheloid cells and
lymphocytes was shown [Figure 3]c. There was no giant cell or foreign body in
the whole specimen. Special stains, Gomori methenamine silver (GMS) and
diastase-periodic acid-Schiff (d-PAS) revealed negative findings. The patient
was diagnosed as chronic folliculitis and granuloma caused by bee sting
acupuncture treatment. For anti-inflammatory effect, he was treated with oral
and topical antibiotics for a short period. The lesions showed slight
improvement but the patient was not able to be followed-up…
Folliculitis is an inflammation in the perifollicular area
that presents as erythematous papules and pustules on the trunk, neck and groin
area. The causes of folliculitis are mostly infection, bacterial organisms,
fungi such as Pityrosporum, viruses, and demodex. Histopathologic findings of
chronic folliculitis differs from acute folliculitis, that it shows perifollicular
infiltration composed of lymphoid cells, histiocytes and plasma cells rather
than neutrophils.
Granulomatous inflammation is a distinctive inflammatory
pattern characterized by granulomas, containing epitheloid histiocytes. Of the
five histological types of granuloma, foreign body granulomatous reaction is
divided into two subtypes, allergic and non-allergic. Foreign body type giant
cells and foreign body surrounded by numerous histiocytes and lymphocytes are
characteristically visualized in the non-allergic type. Besides, granuloma
composed of histiocytes is seen in the allergic type, and phagocytosis of
foreign body is not seen. [2] The granuloma of this patient is suggested to be
an allergic type foreign body granulomatous reaction due to remained poison sac
or neural plexus in the skin, not due to the stinger which should have been
discovered in the serial section of the specimen.
Although several reports had been published in Korean
literatures, there are only five reports of complications of bee sting
acupuncture in English literatures, since apitherapy is usually performed in
Asian and Middle Eastern countries. Only one case of the five English
literatures is a dermatologic complication. Therefore, we report the first case
of chronic folliculitis associated with granuloma as a complication of bee
sting acupuncture therapy, and no reports of chronic folliculitis combined with
granulomatous reaction as in our case have been reported.
Bee Venom
Tuesday, June 18, 2013
Texas Man Uses Bee Venom Therapy to Treat MS
Man Hopes to Sting Away Effects of MS
By Kimberly Sutton, The Courier, 6/16/2013
THE WOODLANDS — The fatigue from Alan Swor's multiple
sclerosis was so bad that he had to stop and rest while brushing his teeth or
while shaving.
However, the 48-year-old resident of The Woodlands is
feeling much better and the fatigue is almost gone since starting a treatment
regimen that involves stinging himself with bees. It's called Bee Venom
"It hurts," Swor said about the stings.
Swor turned to Bee Venom Therapy because his doctor's
prescriptions were not effective.
"Nothing that the doctor told me was helping. I was using
all kinds of drugs to treat MS symptoms," he said.
His sister, Brenda Vozzo, is his health care provider and
assists him by picking up bees from the Montgomery County Beekeeper Association
three times per week and stinging him with about 30 bees during each treatment.
Beekeepers are donating the bees to Swor at no cost, he said.
A friend told Swor about Bee Venom Therapy and he began to
research it. He found Alan Lorenzo's website, www.beewelltherapy.com. Lorenzo
lives in Stanford, Conn., and flew to Houston to train Swor and his sister.
"You need to know what to do and where to sting yourself,"
Lorenzo said. "You just can't sting yourself anywhere and expect it to work,"
Lorenzo is certified in Apitherapy, using bees and products
of the hive to treat health conditions. He is a member of the American
Apitherapy Society.
"It's been called America's best-kept medicine secret,"
Lorenzo said.
Bee Venom Therapy is the therapeutic application of honeybee
venom through live bee stings to bring relief and healing for various spinal,
neural, joint or musculo-skeletal ailments, according to Lorenzo's website.
Lorenzo said bee venom is antibacterial, antiviral and kills
cancer cells.
"Only during the first stage, if you sting a cancer tumor
with a bee sting, it disappears," he said.
Conditions that respond to the treatment are Parkinson's
disease, Alzheimer's, depression, fibromyalgia, bursitis, tendinitis, lupus and
many more, Lorenzo said…
Bee Venom
Monday, June 17, 2013
Toronto Documentary About Bee Sting Therapy Cost Less Than $1,000 to Make
Longtime Toronto filmmaker John Board, 78, endures more than
1,200 stings in all in his documentary
The Star, 6/15/2013
Would you be brave enough to clasp a writhing, angry
honeybee in tweezers and let it sting you? How about 30 stings at a time —
several times a week over the course of an entire summer — in and around your
Longtime Toronto assistant director , 78, endures more than
1,200 stings in all in his documentary Me, the Bees and Cancer, a film he made
in 2012 for less than $1,000 as one of five features funded through the 1K Wave
Challenge, launched by director Ingrid Veninger and The Royal cinema's Stacey
"If I'm on a TV movie or series, I would probably spend
$1,000 on a lunch," said Board to help put his meager budget in context. "A
thousand dollars a day is barely taking care of your food on a smallish
Diagnosed with cancer after he discovered a lump under his
arm, Board chose to treat his illness with homeopathy, healthy diet and regular
doses of bee venom — an ancient and medically controversial practice involving
bee hive products called apitherapy — on and around his tumor…
Me the Bees and Cancer premieres at the Royal Cinema, 608
College St. W. June 21.
Bee Venom
Sunday, June 16, 2013
Indian Stingless Bee Propolis Demonstrates Anticancer Activity
Evid Based Complement Alternat Med, 2013;2013:928280
Indian stingless bee propolis has a complex chemical nature
and is reported to possess various medicinal properties. In the present study,
anticancer activity of the ethanolic extract of propolis (EEP) was explored by
testing the cytotoxic and apoptotic effect in four different cancer cell lines,
namely, MCF-7 (human breast cancer), HT-29 (human colon adenocarcinoma), Caco-2
(human epithelial colorectal adenocarcinoma), and B16F1 (murine melanoma), at
different concentrations.
Cytotoxicity was evaluated by MTT assay and Trypan blue dye
exclusion assay. EEP at a concentration of 250 μg/mL exhibited ≥50% mortality
in all cell lines tested (i.e., IC50 value). EEP revealed a concentration and
time dependent cytotoxic effect. Apoptosis was estimated by differential
staining (ethidium bromide/acridine orange) and TUNEL (deoxynucleotidyl transferase-dUTP
nick end labeling) assay. Light microscopy and atomic force microscopy
demonstrated morphological features of apoptosis in all the cell lines after
treatment with 250 μg/mL EEP for 24 h.
Thus, early onset of apoptosis is the reason for anticancer
activity of Indian stingless bee propolis. Further, the antioxidant potential
of Indian stingless bee propolis was demonstrated to substantiate its
anticancer activity.
Saturday, June 15, 2013
Malaysian Honeys Have High Antibacterial Potency Derived From Total and Non-Peroxide Activities
Antibacterial Activity of Selected Malaysian Honey
BMC Complement Altern Med, 2013 Jun 10;13(1):129
Antibacterial activity of honey is mainly dependent on a
combination of its peroxide activity and non-peroxide components. This study
aims to investigate antibacterial activity of five varieties of Malaysian honey
(three monofloral; acacia, gelam and pineapple, and two polyfloral; kelulut and
tualang) against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and
Pseudomonas aeruginosa.
Minimum Inhibitory Concentration (MIC) and Minimum
Bactericidal Concentration (MBC) were performed for semi-quantitative
evaluation. Agar well diffusion assay was used to investigate peroxide and
non-peroxide activities of honey.
The results showed that gelam honey possessed lowest MIC
value against S. aureus with 5% (w/v) MIC and MBC of 6.25% (w/v). Highest MIC
values were shown by pineapple honey against E. coli and P. aeruginosa as well
as acacia honey against E. coli with 25% (w/v) MIC and 50% (w/v) MBC values.
Agar inhibition assay showed kelulut honey to possess highest total
antibacterial activity against S.aureus with 26.49 equivalent phenol
concentrations (EPC) and non-peroxide activity of 25.74 EPC. Lowest
antibacterial activity was observed in acacia honey against E. coli with total
activity of 7.85 EPC and non-peroxide activity of 7.59 EPC. There were no
significant differences (p > 0.05) between the total antibacterial
activities and non-peroxide activities of Malaysian honey. The intraspecific
correlation between MIC and EPC of E. coli (r = -0.8559 was high while that
between MIC and EPC of P. aeruginosa was observed to be moderate (r = -0.6469).
S. aureus recorded a smaller correlation towards the opposite direction (r =
0.5045). In contrast, B.cereus showed a very low intraspecific correlation
between MIC and EPC (r = -0.1482).
Malaysian honey, namely gelam, kelulut and tualang, have
high antibacterial potency derived from total and non-peroxide activities,
which implies that both peroxide and other constituents are mutually important
as contributing factors to the antibacterial property of honey.
Friday, June 14, 2013
Bee Venom Used to Treat Range of Ailments in China
Stung for a Cure
By Global Times, 6/12/2013
When Chi Cheng was stung by a bee last year, he was
surprised to experience relief from his spinal arthritis, rather than the usual
pain and swelling. Chi, a 40-year-old traditional Chinese medicine doctor, had
battled rickets for around a decade before his bee sting.
Now a convert of apitherapy, the medical use of bee products
including venom, Chi doesn't hesitate to unleash his bees on patients suffering
a wide range of ailments...
Bee Venom
Thursday, June 13, 2013
Medicinal Manuka Not All Equal: Research
GEOFF LEWIS, Waikato Times, 6/9/2013
Thirty years of research into the therapeutic uses of honey
has been condensed into one spot - and written in language suited to the
no-specialist reader by long- serving Waikato University Professor Peter Molan.
Professor Molan, 69, passed 40 years at Waikato in February,
but retains a passion for his subject.
He recently completed his "labour of love" -
condensing into one website the knowledge he has accumulated over three decades
of research into the use of honey as a medicine.
"This has been written in simple language to make it
fully accessible to the general public and it gives details of all the research
on honey at Waikato University and the research on therapeutic properties of
honey that has been done by others elsewhere in the world."
Professor Molan said honey has been known for its medicinal
uses for more than 4000 years and continued to be used even after the
development of antibiotics in the 1940s.
"The challenge has been to understand and provide a
scientific explantation of how honey works as an anti-bacterial and
anti-inflammatory agent. We have discovered that honeys vary widely in their
potency and manuka honey is the best. However, there is still variation within
manuka honeys depending on the variety and the purity of the nectar
Professor Molan said there are six or seven varieties of
manuka which are believed to have arrived in New Zealand from Australia,
probably with birds, before the last ice age…
Apitherapy and Beekeeping,
Wednesday, June 12, 2013
Bees Deprived of Honey as Food Have Weaker Immune Systems
Honeybee Food May Contribute to U.S. Colony Collapse
BOSTON (Reuters) - Bee keepers' use of corn syrup and other
honey substitutes as bee feed may be contributing to colony collapse by
depriving the insects of compounds that strengthen their immune systems,
according to a study released on Monday.
U.S. bee keepers lost nearly a third of their colonies last
winter as part of an ongoing and largely unexplained decline in the population
of the crop-pollinating insects that could hurt the U.S. food supply.
A bee's natural food is its own honey, which contains compounds
like p-coumaric acid that appear to help detoxify and strengthen a bee's
immunity to disease, according to a study by scientists at the University of
Apitherapy and Beekeeping,
Tuesday, June 11, 2013
Review of Patent Application, Biological Constituents of Propolis
Recent Progress of Propolis for Its Biological and Chemical
Compositions and Its Botanical Origin
Evid Based Complement Alternat Med, 2013;2013:697390
Propolis is the generic name given to the product obtained
from resinous substances, which is gummy and balsamic and which is collected by
bees from flowers, buds, and exudates of plants. It is a popular folk medicine
possessing a broad spectrum of biological activities. These biological
properties are related to its chemical composition and more specifically to the
phenolic compounds that vary in their structure and concentration depending on
the region of production, availability of sources to collect plant resins,
genetic variability of the queen bee, the technique used for production, and
the season in which propolis is produced.
Many scientific articles are published every year in
different international journal, and several groups of researchers have focused
their attention on the chemical compounds and biological activity of propolis.
This paper presents a review on the publications on propolis
and patents of applications and biological constituents of propolis.
Monday, June 10, 2013
Propolis Component May Help Treat Thrombosis
Caffeic Acid Phenethyl Ester Inhibits Endothelial Tissue Factor Expression
Biol Pharm Bull, 2013;36(6):1032-5
Caffeic acid phenethyl ester (CAPE) is a component of
honeybee hives with various beneficial properties. Tissue factor (TF), the key
trigger of thrombosis, is expressed in human endothelial cells.
This study was designed to investigate whether CAPE modulates
TF expression in human aortic endothelial cells (HAECs). Western blots and
real-time polymerase chain reactions were performed. CAPE (10(-7)-10(-5) m)
inhibited tumor necrosis factor (TNF)-α induced endothelial TF protein
expression by 2.1-fold at 10(-5) m (p < 0.0001). Similarly, TF surface
activity was reduced (p < 0.02). In contrast, TF mRNA expression, TF
promoter activity, and mitogen-activated protein (MAP) kinase activation
remained unaltered.
Sunday, June 09, 2013
Propolis May Help Treat Sleeping Sickness
In Vitro Evaluation of Portuguese Propolis and Floral
Sources for Antiprotozoal, Antibacterial and Antifungal Activity
Phytotherapy Research, Early View
Propolis is a beehive product with a very complex chemical
composition, used since ancient times in several therapeutic treatments. As a
contribution to the improvement of drugs against several tropical diseases
caused by protozoa, we screened Portuguese propolis and its potential floral
sources Populus x Canadensis and Cistus ladanifer against Plasmodium
falciparum, Leishmania infantum, Trypanosoma brucei and Trypanosoma cruzi.
The toxicity against MRC-5 fibroblast cells was evaluated to
assess selectivity. The in vitro assays were performed following the
recommendations of WHO Special Programme for Research and Training in Tropical
Diseases (TDR) and revealed moderate activity, with the propolis extracts
presenting the relatively highest inhibitory effect against T. brucei.
Additionally, the antimicrobial activity against Staphylococcus aureus, Candida
albicans, Trichophyton rubrum and Aspergillus fumigatus was also verified with
the better results observed against T. rubrum. The quality of the extracts was
controlled by evaluating the phenolic content and antioxidant activity.
The observed biological activity variations are associated
with the variable chemical composition of the propolis and the potential floral
sources under study.
Saturday, June 08, 2013
Sterilized Honey Combats Infections in Dialysis Catheters
Jim Kling, Medscape Today, 5/20/2013
ISTANBUL, Turkey — A sterilized honey preparation was
effective in preventing infections at the site of peritoneal dialysis
catheters, according to a study presented here at the European Renal
Association-European Dialysis and Transplant Association (ERA-EDTA) 50th
However, the honey preparation underperformed versus
mupirocin in patients with diabetes, said presenter Carolyn van Eps, PhD, staff
nephrologist at the Princess Alexandra Hospital, in Brisbane, Australia.
There is little evidence regarding the optimal strategy for
prevention of infection in peritoneal dialysis catheters. "Honey has
potential advantages," Dr. van Eps told Medscape Medical News. "A
very broad range of germs are covered by honey, including gram-positive and
gram-negative bacteria, and fungi, as well as multi-drug resistant organisms.
And it has not been shown in any study to induce antibiotic resistance, which
can be a problem with mupirocin. Honey also helps disrupt biofilms," which
can develop on the surface of catheters…
"Honey was not better and not worse compared to
mupirocin. Patients with diabetes seemed to do a bit worse when we used honey
compared to mupirocin, and there were more withdrawals from the trial in people
who used honey, and that was due to a combination of reasons because the
patients or physician wanted to withdraw, or they got a local reaction,"
said Dr. van Eps.
"For those reasons, honey is probably not the ideal
firstline recommendation, but it probably does have a role in patients who we
know have organisms that are resistant to mupirocin, or in patients who have
local reactions to mupirocin," she said…
Friday, June 07, 2013
Antimicrobial Activities of Bee Pollen Tested
The Effects of Bee Pollen Extracts on the Broiler Chicken's
Gastrointestinal Microflora
Res Vet Sci, 2013 Aug;95(1):34-7
The aim of this study was to investigate the effects of bee
pollen ethanolic extracts on the in vivo gastrointestinal tract microflora
colonization of broiler chickens.
A completely randomized experiment based on six treatments
(different concentrations of bee pollen - 0, 5, 15, 25, 35 and 45gkg(-1) diet)
was used during 7weeks. The highest count of faecal Enterococci was found in
the experimental group with the addition of 15g of pollen (8.85±0.87log
CFUg(-1)) per 1kg of feed mixture. The highest count of Lactobacilli was
detected in the experimental group with 35g of pollen per 1kg of feed mixture
and the highest number of the Enterobacteriaceae genera count was found in the
control group (8.43±0.15log CFUg(-1)).
Moreover, the MALDI TOF MS Biotyper identified the following
genera: Escherichia coli, Proteus mirabilis, Klebsiella oxytoca, as well as
Lactobacillus acidophilus, L. crispatus, L. fermentum and L. salivarius from
the Lactobacilli group and Enterococcus avium, E. casseliflavus, E. cecorum, E.
faecalis, E. faecium, E. gallinarum, E. hirae and E. malodoratus from the
Enterococci group. Additionally, the in vitro antimicrobial activities of
pollen against five bacteria species isolated from gastrointestinal tracts of
chickens were tested.
The best antimicrobial effect of the pollen extract was
detected against K. oxytoca.
Bee-Collected Pollen
Thursday, June 06, 2013
Tualang Honey May Help Treat Breast Cancer
Inhibitory Effects of Tualang Honey on Experimental Breast
Cancer in Rats: A Preliminary Study
Asian Pac J Cancer Prev, 2013;14(4):2249-54
The study was conducted to determine the effect of Malaysian
jungle Tualang Honey (TH) on development of breast cancer induced by the
carcinogen 7,12-dimethylbenz(α)anthracene (DMBA) in rats.
Forty nulliparous female Sprague-Dawley rats were given 80
mg/kg DMBA then randomly divided into four groups: Group 1 served as a Control
while Groups 2, 3 and 4 received 0.2, 1.0 or 2.0 g/kg bodyweight/day of TH,
respectively, for 150 days.
Results showed that breast cancers in the TH-treated groups
had slower size increment and smaller mean tumor size (≤2cm3) compared to
Controls (≤8cm3). The number of cancers developing in TH-treated groups was
also significantly fewer (P < 0.05). Histological grading showed majority of
TH-treated group cancers to be of grade 1 and 2 compared to grade 3 in
controls. There was an increasing trend of apoptotic index (AI) seen in
TH-treated groups with increasing dosage of Tualang Honey, however, the mean AI
values of all TH-treated groups were not significantly different from the
Control value (p > 0.05).
In conclusion, Tualang Honey exerted positive modulation
effects on DMBA-induced breast cancers in rats in this preliminary study.
Wednesday, June 05, 2013
Propolis Component May Help Prevent Blood Clots
Caffeic Acid Phenethyl Ester Inhibits Endothelial Tissue
Factor Expression
Biol Pharm Bull, 2013;36(6):1032-1035
Caffeic acid phenethyl ester (CAPE) is a component of
honeybee hives with various beneficial properties. Tissue factor (TF), the key
trigger of thrombosis, is expressed in human endothelial cells.
This study was designed to investigate whether CAPE
modulates TF expression in human aortic endothelial cells (HAECs).
Western blots and real-time polymerase chain reactions were
performed. CAPE (10-7-10-5 m) inhibited tumor necrosis factor (TNF)-α induced
endothelial TF protein expression by 2.1-fold at 10-5 m (p < 0.0001).
Similarly, TF surface activity was reduced (p < 0.02). In contrast, TF mRNA
expression, TF promoter activity, and mitogen-activated protein (MAP) kinase
activation remained unaltered.
In conclusion, CAPE inhibits TF protein expression and
activity at the posttranscriptional level thereby exhibiting anti-thrombotic
Tuesday, June 04, 2013
Honey Gel a Good Alternative for Treating Burn Wounds
The Effect of a Honey Based Gel and Silver Sulphadiazine on Bacterial
Infections of in vitro Burn Wounds
Burns, 2013 Jun;39(4):754-9
Bacterial contamination remains a constant threat in burn
wound care. Topical treatments to combat contaminations have good bactericidal
effects but can have detrimental effects for the healing process. Treatments
with for example silver can increase healing times. Honey based products can be
a good alternative as it is antibacterial and patient-friendly.
We evaluated the bactericidal and cytotoxic effects of a
honey based gel and silver sulphadiazine in a human burn wound model with
Pseudomonas aeruginosa.
After adding 10(5)colony forming units of P. aeruginosa,
topical treatments were applied on the burn wound models. After 2, 12, 24, 28
and 70h, bacteria were dislodged and counted by plating dilutions. Cytotoxic
effects were evaluated histologically in samples of burn wound models treated
topically for 3weeks, without bacteria.
l-Mesitran Soft significantly reduced the bacterial load
(5-log reduction) up to 24h but did not completely eliminate bacteria from the
burn wounds. After Flammazine(®) treatment, only a few colony forming units
were observed at all time points. In contrast, re-epithelialization was
significantly reduced after application of Flammazine(®) compared to l-Mesitran
Soft or control. This in vitro model of burn wound infection can be used to
evaluate topical treatments.
l-Mesitran Soft is a good alternative for treating burn
wounds but the slightly lower bactericidal activity in the burn wound model
warrants a higher frequency of application.
Monday, June 03, 2013
Honey May Help Prevent Cavities
Antibacterial Activity of Honey on Cariogenic Bacteria
J Dent (Tehran), 2013 Jan;10(1):10-5
Honey has antibacterial activity. The aim of this study was
to evaluate the antibacterial activity of honey on Streptococcus mutans and
In this in vitro study, solutions containing 0%, 5%, 10%,
20%, 50% and 100%(w/v) of natural Hamadan honey were prepared. Each blood
(nutrient) agar plate was then filled with dilutions of the honey. The strains
of bacteria were inoculated in blood agar for 24 hours at 37°C and were
adjusted according to the McFarland scale (10×10 cfumcl(-1)). All assays were
repeated 10 times for each of the honey concentrations. Data were analyzed by
non parametric Chi-Square test. Statistical significance was set at α=0.05.
Significant antibacterial activity was detected for honey on
Streptococcus mutans in concentrations more than 20% and on Lactobacillus in
100% concentration (P < 0.05).
It seems that antibacterial activity of honey could be used
for prevention and reduction of dental caries.
Sunday, June 02, 2013
Bee Venom Spray Stimulates Immune Response
Immunoprophylactic Effects of Administering Honeybee (Apis
melifera) Venom Spray against Salmonella Gallinarum in Broiler Chicks
J Vet Med Sci, 2013 May 30
Antibiotics continue to be used as growth promoters in the
poultry industry. Honeybee (Apis melifera) venom (HBV) possesses a number of
beneficial biological activities, particularly for regulating the immune
The aim of the present study was to evaluate the
immunoprophylactic effects of HBV against Salmonella Gallinarum in broiler
chicks as an initial step towards developing eco-friendly alternatives to
reduce antibiotic use.
HBV was administered using a spray technique. HBV improved
body weight gain, particularly in the presence of infection. Moreover, HBV
enhanced antibody production activity against formalin-killed S. Gallinarum.
The CD4+:CD8+ T lymphocyte ratio, relative mRNA expression levels of
interleukin-18 and interferon-γ, and serum lysozyme activity also increased
following HBV administration before the infection period as well as during
infection. HBV reinforced bacterial clearance and increased survivability
against S. Gallinarum.
Corresponding pathological analyses demonstrated that the HBV-sprayed
group displayed mild and less severe abnormal changes compared with those in
the control group. It was presumed that the prophylactic effects of HBV against
S. Gallinarum were associated with its non-specific immune response stimulating
Thus, HBV may provide an alternative to reduce antibiotic
use in the poultry industry.
Bee Venom
Saturday, June 01, 2013
Historical Aspects of Propolis Research in Modern Times
Evid Based Complement Alternat Med, 2013;2013:964149
Propolis (bee glue) has been known for centuries. The
ancient Greeks, Romans, and Egyptians were aware of the healing properties of
propolis and made extensive use of it as a medicine. In the middle ages,
propolis was not a very popular topic and its use in mainstream medicine
disappeared. However, the knowledge of medicinal properties of propolis
survived in traditional folk medicine.
The interest in propolis returned in Europe together with
the renaissance theory of ad fontes. It has only been in the last century that
scientists have been able to prove that propolis is as active and important as
our forefathers thought.
Research on chemical composition of propolis started at the
beginning of the twentieth century and was continued after WW II. Advances in
chromatographic analytical methods enabled separation and extraction of several
components from propolis.
At least 180 different compounds have been identified so
far. Its antibacterial, antiseptic, anti-inflammatory, antifungal, anesthetic,
and healing properties have been confirmed. Propolis has been effectively used
in treatment of dermatological, laryngological, and gynecological problems,
neurodegenerative diseases, in wound healing, and in treatment of burns and
However, it requires further research that may lead to new
discoveries of its composition and possible applications.
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What's your home worth?
It seems like a simple question, but finding that answer is more complicated than it might seem. Sites like Zillow, Redfin, Eppraisal, and others have built-in home valuation tools that make it seem easy, but how accurate are they? And which one do you believe if you get three different answers? Online valuation tools have become a key part of the home buying and selling process, but they've been proven to be highly unreliable in certain instances. One thing that is for certain is that these valuation tools have reinforced that real estate agents are as vital to the process of pricing a home as they ever were – and maybe even more so now.
There are limitations to every online valuation tool. Most are readily acknowledged by their providers, such as Zillow's "Zestimate", which clearly states that it offers a median error rate of 5%, with varying accuracy across the country. That may not sound like a lot, but keep in mind that amounts to a difference of about $35,000 for a $700,000 home. For Redfin and Trulia, there are similar ranges in results. When you dig deeper into these valuation tools, it's no small wonder that there are discrepancies, as they rely on a range of different sources for information, some more reliable than others.
Redfin's tool pulls information directly from multiple listing services (MLSs) all over the country. Others negotiate limited data sharing deals with those same services, but also rely on public records, as well as homeowners' records. This can lead to gaps in coverage. These tools can serve as helpful pieces of the puzzle when buying or selling a home, but the acknowledged error rate is a reminder of the dangers of relying too heavily on them.
Home valuation tools can be a useful starting point in the real estate process, but nothing compares to the level of detail and knowledge a professional real estate agent offers when pricing a home. An algorithm can't possibly know about a home's unique characteristics or those of the surrounding neighborhood. They also can't answer your questions about what improvements you can make to get top dollar or how buyer behaviors are shaping the market. All of this – and more – can only be delivered by a trusted professional whose number one priority is getting you the best price in a time frame that meets your needs.
If you're curious what your home might be worth, Windermere offers a tool that provides a series of evaluations about your property and the surrounding market. And once you're ready, we're happy to connect you with a Windermere agent who can clarify this information and perform a Comparative Market Analysis to get an even more accurate estimate of what your home could sell for in today's market.

subset: commoncrawl


text:
See a charge from Instacart you don't recognize? Before you reach out to us for help, you might want to double-check it's not—
- An Instacart+ membership fee
- A temporary authorization hold for an order in process
- An adjusted total for changes in your order (e.g., items unavailable or replaced items at a different price).
Temporary authorization hold amounts
For orders in process, we place a temporary authorization hold for a slightly higher amount than your estimated order total. This small difference accounts for potential changes in the final total due to added items, items replaced at a different price, and actual weight of items.
We release the authorization hold after your order is delivered or canceled. It can take 7 days for the pending charge to drop, depending on your bank.
We will only charge you for the total of the items delivered to you.
Final total different from total at checkout
When you place an order, we show you the anticipated total, including estimated taxes and fees. The final total charged to your card may be different if any changes occur during the shopping process, such as—
- An item is out of stock and you're refunded
- You add an item to your order after checkout
- An item you order needs to be replaced, and the replacement has a different price
- An item you order is sold by weight and the exact weight is slightly different
Recurring charges
For security reasons, our payment processor cannot store a card's CVC on file. Our payment processor flags the initial charge as "recurring" so that you don't have to re-enter your card information every time you place an order.
Fraudulent charges
If the scenarios outlined in this article do not apply, and you still feel the charge you see is fraudulent, please email us and include the following information—
- The last four digits of your card number
- The date of the unauthorized charge(s)
- The amount of the unauthorized charge(s)
We recommend talking to us before disputing unknown charges directly with your bank. When a dispute is filed, the associated Instacart account is placed on hold during the investigation, which can take up to 90 days.


text:
Geopolitical tensions have been rife across the globe as election risk took centre stage over the month.
In the USA, France, and UK, political transitions are expected following imminent elections. These "lame duck" periods can create uncertainty in markets as outgoing leaders finalise their terms.
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- David Puts, David Carrier, and Alan R. Rogers. 2023. Contest competition for mates and the evolution of human males. Pp. 317-377 in Oxford Handbook of Human Mating, edited by David M. Buss. Oxford University Press.
Published, 01/27/2023.
https://global.oup.com/academic/product/the-oxford... - Rogers, Alan R. (2022). Beating your neighbor to the berry patch. Peer Community Journal. Vol. 2, e34.
Published, 06/08/2022.
https://peercommunityjournal.org/articles/10.24072... - Rogers, Alan R. (2022). An efficient algorithm for estimating population history from genetic data. Peer Community Journal. Vol. 2, e32.
Published, 06/07/2022.
https://peercommunityjournal.org/articles/10.24072... - Brand CM & White FJ (2022). Estimating bonobo (Panpaniscus) and chimpanzee (Pantroglodytes) evolutionary history from nucleotide site patterns. Proceedings of the National Academy of Sciences of the United States of America. Vol. 119, e2200858119e2200858119. Published, 04/01/2022.
- Jeremy S. Morris, Nala Rogers, Alan R. Rogers & David S. Carrier (2020). Sexual Dimorphism in Skeletal Shape in Voles (Arvicolinae): Disparate Selection on Male Bodies and Female Heads. Journal of Mammalogy. Vol. 101, 951-957.
Published, 08/2020.
https://doi.org/10.1093/jmammal/gyaa076 - Rogers, Alan R., Nathan S. Harris & Alan A. Achenbach (2020). Neanderthal-Denisovan ancestors interbred with a distantly-related hominin. Science Advances. Vol. 6.
Published, 02/20/2020.
https://advances.sciencemag.org/content/6/8/eaay54... - Rogers, Alan R. (2019). Legofit: Estimating Population History from Genetic Data. BMC Bioinformatics. Vol. 20, 526.
Published, 10/28/2019.
https://bmcbioinformatics.biomedcentral.com/articl... - Rogers, Alan R. (2018). Biographical Memoir: Henry C. Harpending, 1944-2016. (pp. 1-23). National Academy of Sciences, USA. Published, 03/31/2018.
- Rogers, Alan R., Bohlender, Ryan J & Huff, Chad D (2017). Reply to Mafessoni and Prufer: Inferences with and without singleton site patterns. National Academy of Sciences. Vol. 114, E10258-E10260. Published, 10/02/2017.
- Early history of Neanderthals and Denisovans. Proceedings of the National Academy of Sciences, USA. doi: 10.1073/pnas.1706426114.
Published, 08/07/2017.
http://www.pnas.org/content/early/2017/08/01/17064... - The heritability of gestational age in a two-million member cohort: Implications for spontaneous preterm birth. Human Genetics, 134(7): 803-808, 2015.
Published, 04/29/2015.
http://link.springer.com/article/10.1007/s00439-01... - Bias in estimates of archaic admixture. Theoretical Population Biology, 100: 63-78.
Published, 01/06/2015.
http://www.sciencedirect.com/science/article/pii/S... - The molecular clock. In: (Thure Cerling, ed) Treatise of Geochemistry -- Archaeology and Anthropology. Elsevier. Published, 02/2014.
- A Late Holocene Population Bottleneck in California Tule Elk (Cervus elaphus nannodes): Provisional Support from Ancient DNA. Journal of Archaeological Method and Theory, 20(3): 495-524. Published, 09/2013.
- Genetic relatedness to sisters' children has been underestimated. Proceedings of the Royal Society, Series B. 280 (1751). doi: 10.1098/rspb.2012.1937. Published, 11/28/2012.
- Rogers, Alan R. The evidence for evolution. Chicago University Press. Published, 06/15/2011.
- Understanding Climate's Influence on Human Evolution. National Academies Press.
Published, 01/01/2010.
http://dels.nas.edu/resources/static-assets/materi... - Detecting positive selection from genome scans of linkage disequilibrium. BMC Genomics 11(1):839-834. Published, 01/01/2010.
- Mobile Elements Reveal Small Population Size in the Ancient Ancestors of Homo sapiens. Proceedings of the National Academy of Sciences. 107(5):2147–2152. Published, 01/01/2010.
- Rogers, Alan R. and Chad Huff. Linkage Disequilibrium between Loci of Unknown Phase. Genetics.
Published, 2009.
Research Statement
All of my research involves evolution, but there are two distinct threads. The first of these (in human evolutionary genetics) involves using genetic data to learn about human evolutionary history. The second (in human evolutionary ecology) involves building models in order to test hypotheses about adaptive evolution.
Research Keywords
- Human Population Genetics
- Evolutionary Ecology
- Evolution
- Neanderthal-Denisovan ancestors interbred with a distantly-related hominin. Annual meeting of the Southwest Association of Biological Anthropologists, Tempe AZ. Conference Paper, Refereed, Presented, 11/02/2019.
- Superarchaic admixture confirms a deep separation of Neanderthals and Denisovans. American Association of Physical Anthropologists. Cleveland, OH. Conference Paper, Refereed, Presented, 03/2019.
- Superarchaic admixture confirms a deep separation of Neanderthals and Denisovans. American Association of Physical Anthropologists. Cleveland, OH. Presentation, Accepted, 03/2019.
- The early history of Neanderthals and Denisovans. International Symposium on Biomolecular Archaeology. Jena, Germany. Poster, Presented, 09/2018.
- Genetic evidence for early separation of Neanderthals and Denisovans and an early archaic bottleneck. American Association of Physical Anthropologists. Austin, TX. Presentation, Presented, 04/2018.
- Hyperarchaic admixture into Denisovans. University of Utah. Invited Talk/Keynote, Presented, 02/2018.
- Hyperarchaic admixture into Denisovans. Rutgers University. Invited Talk/Keynote, Presented, 02/2018.
- Simultaneous Estimates of Archaic Admixture and Ancient Population Sizes. Poster, Presented, 07/04/2017.
- The origin of Neanderthals and Denisovans. Society of Molecular Biology and Evolution. Poster, Presented, 07/03/2017.
- Genetic evidence for an archaic human diaspora. American Association of Physical Anthropologists. New Orleans. Presentation, Presented, 04/20/2017.
- Do species change? Presentation to Salt Lake Oasis. Invited Talk/Keynote, Presented, 02/19/2017.
- Panel discussion at Darwin Day Celebration, Humanists of Utah. Panel, Presented, 02/11/2017.
- Legofit: a new estimator of the history of population size and admixture. Southwest Association of Biological Anthropologists, Arizona State University. Poster, Presented, 11/05/2016.
- Bias in estimates of archaic admixture. Genetics of Admixed Populations. Satellite meeting of the Society for Molecular Biology and Evolution, San Antonio, TX. Poster, Presented, 05/19/2016.
- Allele sharing between archaic and modern humans. Annual meeting of the American Society of Physical Anthropologists, Atlanta, GA. Presentation, Presented, 04/16/2016.
- The recent history of human population size. American Society of Human Genetics. Poster, Presented, 10/07/2015.
- Discussant for Science Movie Night: Creation. Natural History Museum of Utah. Presentation, Presented, 07/14/2015.
- Genetics and the Neolithic of Europe. Lecture to the Department of Anthropology, University of Utah. Invited Talk/Keynote, Presented, 11/07/2013.
- Did Humans Evolve? Keynote address at Darwin Day celebration, University of Utah. Invited Talk/Keynote, Presented, 02/09/2013.
- Discussant, public screening of "Creation", film series sponsored by Department of Anthropology, University of Utah. Other, Presented, 02/22/2012.
- Presentation on evolution to science teachers of the Alpine School District. Presentation, Presented, 02/16/2012.
- First of two presentations on the evidence for evolution, Sunday school class for children in their early teens, South Valley Unitarian Church, SLC. Presentation, Presented, 02/12/2012.
- Public lecture on the evidence for evolution, keynote address for the Darwin Day Celebration, Utah Valley University.
Invited Talk/Keynote,
Presented, 02/08/2012.
http://www.uvu.edu/csh/symposium/alanrogers.htm - Public Lecture on the evidence for evolution. Humanist Society. North Valley Unitarian Church, SLC. Presentation, Presented, 01/12/2012.
- Lecture on the evidence for evolution to NAKAMA, Research Admin, University of Utah. Presentation, Presented, 10/07/2011.
- Public lecture about my new book, The Evidence for Evolution, at the King's English Bookstore. Presentation, Presented, 09/29/2011.
- Public lecture: The evidence for evolution. Adventures in Anthropology Lecture Series, Gould Auditorium, University of Utah.
Invited Talk/Keynote,
Presented, 01/12/2011.
Software Titles
- Legofit. A computer package that uses genetic data to estimate the deep history of population size, subdivision, and admixture. Release Date: 03/09/2017. Inventors: Alan Rogers. Distribution List: Available free of charge at https://github.com/alanrogers/legofit.git.
- PopHist. PopHist is a computer package that estimates the recent history of population size from genetic data. Release Date: 08/2014. Inventors: Alan R. Rogers. Distribution List: https://github.com/alanrogers/pophist.


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Do-It-Yourself Guide to Apostille Veterinary certificate
Veterinary certificate Apostille
An Apostille for Veterinary certificate is to certify the authenticity of the signature on the document. The Apostille stamp is accepted in all Hague Convention Participating countries. To Apostille a Veterinary certificate,it must be notarized by a notary public in the same state, where the document was issued. You can obtain an apostille for your Veterinary certificate from the Secretary of State office in the same State where the notary is licensed
Document Apostille Guide
On 1961, more than 120 countries have signed the Hague Apostille Treaty to abolish foreign document legalization requirements and replace it with a single certification, which is the Apostille seal. There are two entities in the United States that are authorized to issue apostilles, depending on the document type.
- Apostille public State document from the local Secretaries of State offices in all 50 States.
- Apostille federal documents from the US Department of State in Washington DC.
Veterinary certificate Embassy/ Consular Legalization
There are many countries that didn't sign the Apostille Treaty and still require embassy legalization to accept foreign documents. A Veterinary certificate destined for use in a Non-Hague Participating Country requires certification from the Secretary of State, authentication from the US Department of State in Washington DC and finally legalization from the embassy of the destination country in Washington DC or on of it consulates.


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We are The Maids, the only company providing residential cleaning services in Huntington Beach & Huntington Harbor that specializes exclusively in house cleaning for health. Our cleaning systems, products and extensive industry experience have given us the ability to make your house cleaner and healthier than ever before, and we provide a safer environment than any other house cleaning service. Our 22-Step Healthy Touch® Deep Cleaning System, along with our four-person cleaning teams, our environmentally preferred products, our state-of-the-art equipment and our unique cleaning process provide customers an affordable line of home cleaning services that cannot be matched anywhere else. We are the best in the residential housecleaning industry.
We Can Help You Get Your Huntington Beach & Huntington Harbor House Cleaner than Ever
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We do not move dirt – we remove it! By eliminating cleaning tools such as dust wands and dust mops that are known for spreading dirt from one place to another, we provide environmentally friendly cleaning services that not only make a customer's house cleaner on the surface, but deep down as well. This attention to detail is what homeowners love.
Customers utilizing our cleaning services most often say the reason they need housecleaning help is because they don't have enough time to get everything done. If you are feeling time starved, stressed, and feel there are not enough hours in the day to get your house cleaner, why not have someone else do your housecleaning. And there's no better choice than The Maids – the most thorough cleaners in the industry. Do not wait, your very own four-person cleaning team is ready and waiting to dust, vacuum and detail clean every room of your home.
The Maids Healthy Touch® Deep Cleaning System was created to ensure a healthy cleaning process and provide you and your family with the healthiest living environment possible. Healthy Touch® is based on a 22-step plan of action that combines healthy cleaning supplies with a strict attention to detail.
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Growth Through Adversity
The Growth Initiative is an ongoing research program that aims to better understand the conditions under which people can experience positive behavioral changes after going through highly stressful adverse events. They intend to uncover the scope of this growth, and the factors that limit growth. This research program is based at Wake Forest University and the University of Pennsylvania and made possible through a grant from the John Templeton Foundation
Changing in the Aftermath of Adversity
Nietzsche's claim that "what does not kill me makes me stronger" has great intuitive appeal, and many of us believe that experiencing hardship and troubles can leave us in a better place than we were before. Psychological scientists have become increasingly interested in studying the positive life changes that people report in the aftermath of highly stressful life events including (but by no means limited to) diagnosis with terminal illness, bereavement, and sexual assault. This notion has been referred to with many different names, but the construct is most commonly referred to by scientists as adversarial growth, posttraumatic growth, stress-related growth, altruism born of suffering and benefit finding.
Growth through Adversity
Posttraumatic growth (PTG) is a scientific construct that strives to capture these positive transformations in beliefs and behavior. PTG may take five forms: improved relations with others, identification of new possibilities for one's life, increased personal strength, spiritual change, and enhanced appreciation of life. These positive changes relate to the development of important qualities of character, such as diligence, generosity, love, purpose, and humility. Thus, adversity may provide opportunities for the development of important character traits, echoing St. Paul's insight that "suffering produces endurance, and endurance produces character, and character produces hope" (Romans 5: 3-4).
For more information on the science of growth through adversity, see the Growth Initiative website.


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Welcome to NuSoapdom! Tenth Anniversary Version!
Can you believe it? This is www.Soapdom.com's fourth version. Around here, we are calling it Soapdom v4. We've come a long way from our humble beginnings as Turtle-Run.com back in 1999. Those of you who have been with us since then will remember our adorable mascot, Bob the Purple Turtle.
Ain't he cute? We went from Turtle-Run's humble beginnings...
...to a more dynamic content driven site in 2002:
...to here in 2006:
...to where we are now in 2009:
With each new version of the site -- and the logo -- we brought you new features and top notch content. This go round we are extremely, extremely excited about what v4 offers. Here is just a sample:
Soapdom Social Network
It's our very own Facebook-MySpace-type community right here at www.Soapdom.com. You can write and manage blogs, upload photos, videos, build a friends list, and so much more. Why have a soaps-related page on Facebook, when you can do it right here at Soapdom, Where Soap Operas Rule! Start your page and invite your friends today.
Color Code
This is one of my favorite features. The default color for Soapdom is this cool shade of pink. But if your look in the drop down where you log in or register, you will see four small boxes. Click on the blue box and the site turns blue! Click on the orange box and the site turns orange. Click on the gree box and --- say it with me soap fans --- the site turns green. Click pink and you are back to where you started!
Chat and Forums
As usual, we still have our chat rooms -- one for each soap, an audiorium, and an editors chat. And our message boards. Come share your thoughts with everyone.
As in v3, you can comment on every article throughout the site. All your comments will be listed in your member area's "comment section."
The more you comment, blog, add photos, videos, etc to the site, the more points you'll get. The more points you get, the more of a soap opera expert you become. Top scorers will be entered into contests at the various intervals thoughout the year and you can win some very hot prizes. More info on this to come.
Speaking of contests, we'll have more of them. There will be polls, photo galleries, games, and more.
Yup. We intend to offer a featured video a few times a week. If it's not one we've shot and produced ourselves, it will be one from YouTube or one directly produced by our content partners. It could even be one of yours. Stay tuned for more on this cool new feature.
Finally, finally, finally we will get our Soapdom store off the ground.
As with v3, we offer a wide range of Newsletters, from the The Soapdom News to newsletters on each show, and of course the ever popular Sneak Peeks Newsletter. Be sure to sign up for your favorites.
Last But Not Least
As usual, we will continue to provide you with the latest in soap opera breaking news, casting news, show background, in depth interviews, opinion articles and oh so much more.
So come and join us Inside the Bubble at www.Soapdom.com.
Linda Marshall-Smith
QueenRuler, www.Soapdom.com
QueenRuler said:
... Glad to see you guys tooling around the site. Postalgirl, you have now beat me as the top member of the site! See the bottom of any page, the left hand column for Top Member stats. |
mut51 said:
congrats...tne years! what a great accomplishment, good job! YOu and your website have grown immensely. |


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City Portrait: Split, Croatia
Experiencing The Adriatic Coast Named after a shrub, Split may not have the most exciting or intriguing name but look at one photo, and...
New Mexico - Colorado - Utah - Arizona
Registration Deadline: February 26, 2021
Duration: 14-day vacation, 11 riding days,
1 rest day, 2 travel days
Skill Level: (moderate)
Group Size: 6 – 12 motorcycles
Arrival: Las Vegas, NV
Departure: Las Vegas, NV
Total Distance: 2,050 mi / 3,299 km
Average Daily Mileage: 185 miles / 275 km
Average Temperature: 50–80ºF / 10-27ºC
need to chose photos
Itinerary will be revised, from Las Vegas
Highlights: Albuquerque, NM • Sandia Crest • Santa Fe, NM • Ghost Ranch, NM • Million Dollar Highway • Four Corners • Mesa Verde National Park • Goosenecks State Park • Monument Valley • Antelope Canyon • Lake Powell • Grand Canyon National Park • Canyon de Chelly • White Sands National Park
The Four Corners Tour combines the wide-open expanse of Arizona, the tranquil deserts of New Mexico, the rugged Colorado Rockies, as well as the majesty of Utah's Monument Valley. Four Corners is named for the spot in the American Southwest where four states meet. It is an intersection not only of four states, but a meeting point of prehistoric landscapes, indigenous people, majestic mountains, and modern evolution—especially in terms of exceptional riding on well-maintained roads.
The Four Corners Blue Rim Tour offers an especially rare view of this great country's diversity from the seat of a motorcycle. Exploring this region on two wheels provides a unique riding experience, allowing for a closer connection to its exquisite natural wonders and an appreciation for the natural beauty that transcends the dynamic—and sometimes harsh—landscape. From Monument Valley to the Rocky Mountains, and the Grand Canyon to White Sands National Monument, you will ride through a rich tapestry of American history for a truly memorable motorcycling experience.
As an added bonus the tour includes riding Colorado's serpentine "Million Dollar Highway," an idyllic motorcycle route, which snakes through the Rocky Mountains. With true million-dollar views, this 50-mile stretch starts in Durango, CO and winds its way through grand vistas of unequaled beauty and abandoned mining facilities, arriving in the quirky town of Ouray, the ice-climbing capital of the world.
Starting and ending in Albuquerque, New Mexico this 14-day vacation (of which eleven are full ride days) will traverse an amazingly full 2,050 miles, with ride days averaging a comfortable and leisurely 185 miles. The tour was specifically planned around a mild time of year, with average daytime temperatures of 80˚F, making for optimum riding weather. Join us for the adventurer's essential American Southwest road trip.
Day 1
What Your Tour Includes
Knowledgeable and experienced tour guide
Accommodations at comfortable hotels (13 hotel nights)
All breakfasts
Entrance fees to all parks and other points of interest
A detailed tour information package including maps, guide books, and a T-shirt
Support vehicle (if more than 6 riders)
Motorcycle rental is not included


text: Medicine (UK English , ; US English ) is the science or practice of the diagnosis, treatment, and prevention of disease. The word medicine is derived from the Latin ars medicina, meaning the art of healing. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, prostheses, biologics, and ionizing radiation, among others. Medicine has existed for thousands of years, during most of which it was an art (an area of skill and knowledge) frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). While stitching technique for sutures is an art learned through practice, the knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science. Prescientific forms of medicine are now known as traditional medicine and folk medicine. They remain commonly used with or instead of scientific medicine and are thus called alternative medicine. For example, evidence on the effectiveness of acupuncture is "variable and inconsistent" for any condition, but is generally safe when done by an appropriately trained practitioner. In contrast, medicine outside the bounds of safety and efficacy is termed quackery.


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And in the Zapatista Communities?
Zapatista Army for National Liberation
To the compañer@s of the Sixth:
To whom it may concern:
Compañeroas, compañeros and compañeras:
Now we are going to tell you a little bit about the Zapatista communities, where the bases of support resist and struggle.
What we are going to share with you now comes from reports by the Zapatista compañeras and compañerosin the communities who are coordinators for their commissions (for example, health, education, young people, etc), autonomous authorities, or other organizational coordinators. But along with the compas of theComité [CCRI] we checked to make sure this information wasn't a lie, that things hadn't been altered so that the good things would appear and bad things would remain hidden. The work of these writings is not to lie to our compas of the Sixth nor to those who support us and are in their solidarity. We won't lie to you, to them, nor to anyone else.
If things are going badly we will tell you so clearly, but not so that you feel even more sad on top of everything that is happening in your own geographies and calendars. We tell you because it is our way of being accountable, of letting you know what's happening and so that you know if we are on the path we said we were on or if we have wandered off that path, perhaps repeating the same vices we criticize.
But if we are on the right track, well we want you to know that too in order to bring joy to the collective heart that we are.


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Dear Lifehacker,
There are a lot of people talking about freedom of speech on the internet these days. Some sites say they stand for free speech, but does the first amendment apply to them? Where exactly am I free to speak my mind?
Dear Soapboxer,
The truth is, what your freedom of speech is and where it applies is actually very simple, but our understanding of it has been distorted, mostly because people use "free speech" as a weapon where it doesn't apply, and often as a shield to hide behind when they're being criticized. Even so, free speech has never been a more valuable right, especially on the internet, where governments, companies, and individuals all try to control their image and what people say about them. I'm no constitutional lawyer, but there are plenty of ways to exercise your speech freely online. First, let's brush up on our US civics, shall we?
What the First Amendment Really Says
The first amendment to the Constitution says:
Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof; or abridging the freedom of speech, or of the press; or the right of the people peaceably to assemble, and to petition the Government for a redress of grievances.
This amendment (and all of the other amendments to the Constitution) were added because the Constitution itself, according to its drafters (and the states, which had to ratify it), didn't offer enough protections for the civil liberties from the powers of government. This is very important: freedom of speech, along with the other freedoms in the first amendment, are designed to protect the liberties of the populace against an oppressive government that would seek to squash those rights in its own self-interest. Photo by Brent Payne.
Private entities and private spaces, however, are largely not required to protect your speech, and the first amendment does not protect what you say—only your right to speak. This means that you can say what you choose, but the nature of free speech is that others are free to say what they choose as well, even if it means disagreeing with you or mounting a campaign of people to respond to you. Keep these points in mind as we discuss how your freedom of speech plays out on the internet.
Free Speech and Censorship on the Internet
Earlier in our nation's history, most towns and cities had a "public square" at the heart of a community where people could meet, discuss, and hear the news and issues of the day. It was usually the place where officials made proclamations, candidates spoke and stumped for votes (directly analogous to today's "town hall" meetings), and in general where the people could gather and speak freely. Those public squares have all but disappeared, and while there are still town halls and other public spaces for speech, the true heart of most communities today are private places of commerce or entertainment (malls, stores, stadiums.) Photo by BLMOregon.
Today, most of us turn to the internet because the tools are free and available: Twitter, Facebook, Reddit, newspapers, blogs with comment sections, forums, they all offer one-click methods for us to speak our minds. However, when you leave a comment on a company's Facebook page, post to a Reddit thread, or tweet your grievances, you're speaking in privately owned spaces. This means you should have no expectation that your speech is somehow protected beyond that service's terms of use. That said, when it comes to freedom of speech on the internet, there are two truths that are almost universal:
Most spaces on the internet are privately owned, and have no obligation to allow you to speak freely in their space. Whether it's Facebook removing content that violates its own terms of service, a blog owner deleting a comment they find offensive, or a big company deleting user posts from its Facebook page, your speech may be censored, but you have no first amendment right to free speech in those places. This includes our discussions on Lifehacker—we've always held our community up to high standards, and if you start a discussion we find isn't up to those standards, we reserve our right to dismiss it.
Most companies know it's in their own best interest to allow you to speak freely on their platforms. When you hear any company say "we support/stand for freedom of speech," what they really mean is that by honoring your freedom of speech, they know they can successfully build a community, attract users, attract views, attract advertisers, and make money. They may truly value free speech, don't get us wrong, and most companies know that success means taking the bad with the good, but that doesn't make it your right. They just know it's in their best interest to say they value it, and act accordingly.
While "censorship" can apply to any type of speech suppression, censorship in the context of "free speech" is generally reserved for speech that's suppressed by government or state actors. A company deleting your post on their Facebook page about how their product was a waste of your money, even if you think the post was relevant or witty, is not state suppression of your speech. It may be censorship, but your freedom of speech has not been violated. Photo by Newtown Grafitti.
Remember this when you speak on the internet. While Reddit or Twitter may feel like the new "public square," they aren't. This means your speech is not constitutionally protected unless specified in the terms of use for that service, and those can change at the whim of the service or platform provider. Plus, governments know that they can lean on companies to change their rules (see SOPA, PIPA, and ACTA) and restrict private speech as well (see Twitter working with local governments to censor objectionable material,) regardless of whether they can do it in public. All isn't lost though—some speech is protected, and there are places where you can say what you choose.
What Speech on the Internet Is Protected?
That's a difficult question. Legal challenges abound on this topic, many of which attempt to define what's protected in an era the line between public and private is blurred and the vast majority of people treat the internet like a public space. For example, some argue that clicking "like" is protected speech because of its public nature, and others argue that your tweets and blog posts are protected speech. To date, most courts have come down on the side of "use a private service, you're subject to their rules and moderation, but government cannot interfere with your private speech and individuals cannot silence your speech just because they dislike it." Photo by Thomas Angermann.
Remember when we noted that freedom of speech doesn't stop others from speaking out against you? This point is important too: too often on the internet "freedom of speech" is used as a defense mechanism to deflect criticism, when in reality it was framed in order to promote self-policing and self-criticism of communities and governments by the people. In short, freedom of speech means everyone gets to speak publicly, whether they agree or disagree with you. If you speak your mind (in a public space) and find a group of people shouting back at you, your rights aren't being trampled, you're just unpopular—and all of you have the right to speak.
Where Can I Speak Freely?
So where can you speak freely if you find your opinions are no longer welcome on a company's Facebook page, or if you've been banned from commenting on a blog? You can set up your own space to speak—as in start your own blog and invite people to come and participate in a truly free discussion with you, or start your own Facebook page where you air your grievances with the company that won't respond to you anymore. Again, because these are actually private spaces, your speech is only as protected as your service provider's whim. If you start a free blog at Wordpress or Tumblr, you have to stay inside the lines of acceptable use. If you start a Facebook page, you have to adhere to Facebook's TOS. Make sure to read them carefully.
Your best bet is to get a decent web host and host your own blog where you can say what you like. When you host your own speech, you're now the party with the terms—you can be as lenient or restrictive as you choose. You may not have the audience you wanted (that Facebook page's subscribers or forum's readers), but free speech protects your right to speak—it doesn't force others to listen. You're still subject to your hosting company's TOS, and it's still a semi-private space, but it's the closest you can get to public on the internet, and most hosting companies don't care what you say as long as it doesn't get them into legal trouble.
Good luck, and good luck speaking your mind!
Have a question or suggestion for Ask Lifehacker? Send it to [email protected].
Title photo made using kstudija (Shutterstock).


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PHOENIX — Unlike any cocktail you may be mixing on New Year's Eve, fireworks and pets do not go together.
While you may be celebrating, each explosion in the sky will make for a scary start to 2019 for your furry friends.
"We've heard of dogs jumping over fences ... crawling under fences," said Jose Santiago with the Maricopa County Animal Care and Control in Arizona. "We've heard of dogs jumping through windows."
Santiago explained that pets already hear things at a much higher decibel than humans.
"They don't know what that noise is," Santiago said. "They don't know what that explosion is."
If you are going out on New Year's Eve, Santiago suggests keeping your pet in a room without windows, and to turn on the TV or music.
"If you're home, keep them in a room with you," Santiago said. "Your presence calms them down considerably."
But these holidays are still known to bring hundreds of pets into the shelter. Last year, the shelter saw more than 200 lost animals.
That is why Santiago strongly advises to get your pet micro-chipped as soon as possible.
"If we find a dog that has been running around loose and we scan for that microchip, we will drive them straight home," Santiago said. "They never set foot in the shelter. It's the easiest way to get a dog home."
Plus, the county shelter is closed on New Year's Day. So pet owners will have to wait until Wednesday to start searching the shelter for their lost pet.


text:
Free Shipping on US Orders $85+
Say "Hey" to the Greetings Collection 👋🏼 Click to Place Your Order Now!
JB Yeti or Not Die-namics
This die set coordinates with the Yeti or Not stamp set for perfectly die-cut images. The dies are open inside to allow you to stamp then cut or cut then stamp. This feature also allows for easier removal of the die cuts.
Die-namics, our very own exclusive American-made line of steel dies, work with a variety of die-cutting machines. Find your stack HERE.
November 2023 Release - (6) piece set
Please refer to the coordinating stamp set for approximate die dimensions.


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Plug-in Multifunction 6H40
Plug-in Multifunction 6H40
This single-row, multifunction plug-in holds up to 6 burs securely during sterilization and also serves as a convenient bur stand. The rotating cover allows for the protection of the burs and can be tilted to display burs upright or at an angle.
CAPACITY: 6 instruments
HEIGHT: 4cm
MATERIAL: 304 stainless steel and silicone
Product Code: 1004.103
- Our dental bur plug-ins are made of durable, low maintenance 304 stainless steel and silicone.
- The silicone parts come in different colors allowing for versatility and customization according to your needs.
- The plug-ins are recommended for burs applicable in implant surgery, endodontics, dentures and the placement of amalgams and other dental fillings.
- They are compatible with common sterilization equipment.
Our plug-in models are manufactured out of 304 stainless steel and silicone and can withstand even the heaviest sterilization conditions. During sterilization they can be placed inside a cassette for increased protection, or directly into a pouch. They are compatible with common sterilization equipment and can be placed in a disinfecting container (chemical or ultrasonic treatment) or in an autoclave without any fear of damage. Sterilization can be run at 134°C for 18 minutes at a pressure of 2.2 bar. The free flow of air and fluid in the cassette makes the operation even more efficient.


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Liberal journalist Walter Shapiro, a former Carter speechwriter, self-professed JournoList member, and possessor of one of these most portentous author mug shots I've seen in recent memory has an article at AOL's Politics Daily moaning about the leaker of the now infamous JournoList:
Every entry on Google Groups, where JournoList resided, ended with the cautionary line, "And remember: All postings are off-the-record." But someone — whose motivations were mysterious and whose lack of integrity was obvious — collected all of Weigel's back e-mails and apparently sent the most intemperate comments (ripped out of context) to FishbowlDC, a media gossip website, and the Dally Caller, a new conservative online newspaper. Weigel, who had recently been hired by The Washington Post to write about the conservative movement, resigned from his new job Friday because of the furor.
I do not know Weigel (and actually do not remember most of his postings on JournoList), but I am outraged over what happened to him. It is one thing to castigate a reporter for the accuracy of his journalism or to deride a blogger for the rigor of his arguments. But it is morally repugnant to heist someone's e-mail comments — and to leak them in a way designed to embarrass him with the people whom he is covering. The obvious and odious parallel would be to secretly place a tape recorder on a table at a dinner party and then to turn the most inflammatory sound bites into a podcast.
Which the average New York Times journalist would do in a second if he thought he could get a story out of it that bashed anyone to the right of Pinch Sulzberger or Frank Rich.
(Update: as a reader notes in the comments below, "Isn't that exactly what was done to Gen. McChrystal by Rolling Stone….?")
More from Shapiro:
In another era, Secretary of State Henry Stimson closed the State Department's code-breaking office in 1929 because, as he quaintly explained, "Gentlemen do not read each other's mail." Translating that sentiment in modern and gender-neutral language: "Honorable people do not read each other people's e-mails without permission."
How laudable, how naive, how early 20th century. The zone of privacy these days stops at the edge of your thoughts. It is impossible for any group (and this means liberals, conservatives and middle-of-the-road vegans) to share off-the-record ideas online without running the risk that someone will breach the bonds of trust to score cheap political points. Every time someone like Weigel is humiliated because of quickly typed off-the-cuff comments, it moves us closer to a world where we all communicate in predictable homogenized phrases because who knows where they might end up.
Yes, it will be a sad day when a writer can't use the word "ratf*cker" to describe his subjects while he's assigned to a column titled "Inside the conservative movement and the Republican party," as Weigel's masthead at the Post advertised:
Shapiro's article is titled "The Death of JournoList: Does Privacy End at the Edge of Your Thoughts?" Which seems like a rather disingenuous question for a man of the left to ask, as this is where the terrain invariably ends up, the further and further one moves left.
Which is exactly what the nation has done since January of 2009. Newsweek, owned by the Washington Post, famously screamed on a cover story early last year that "We Are All Socialists Now." And blogger "Doctor Zero" recently noted at Hot Air the correlation between the leviathan socialist state virtually all Beltway journalists begged for when they endorsed Obama in 2008, and the state of journalism itself.
You wanted East Germany on the Potomac? Might as well have all of the trappings, boys.
So does privacy end at the edge of your thoughts? George Orwell's characters in 1984 could easily answer that question. As could Robert Ley, Head of the National Socialist German Labour Front from 1933-1945, who was famously quoted by Hannah Arendt as saying that "The only person who is still a private individual in Germany is somebody who is asleep."
Update: "Why is no one calling for the outing of the 400 JournoList members and an investigation of whether there were any other attempts to collude and to coordinate the media narrative?"
Update: "Oh, good grief. Check out the photo if you want to see the face of modern journalism. In your nightmares . . . ."
Update: Regarding said photo, Jim Hoft adds, along with a screen capture, that at least at the moment, "It's even on his Wikipedia page."


text: About Phoenix Motor Leathers' StorePhoenix Motor Leathers is committed to excellence! That means we want you to be completely satisfied with every purchase. If you're not satisfied with one of our products for any reason, it can be returned in new, unused condition within 30 days and we will promptly exchange your merchandise or issue you a store credit to spend in the future, whichever you prefer. Customer will be responsible for additional shipping charges if they apply. Items sold by us are covered by a 30-day to lifetime warranty, depending on the product. Please email us for any warranty issues. Thanks for stopping by! Learn more... |