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Home Cure for Lupus
Natural Lupus Treatment Ebook by Dr. Gary Levin
Dr. Gary Levin is helping lupus patients with a step-by-step system that rehabilitates your immune system and boosts the bodys natural supporting systems to begin eliminating all lupus symptoms. The healing process of Natural Lupus Treatment is carried out through a simple step-by-step method that rehabilitates your immune system and boosts your supporting body systems to eliminate all lupus symptoms, the joint pains and swelling etc. Actually there is no cure yet discovered for lupus, however, you will find methods to control and manage its signs and symptoms. The aim of the treatments of lupus generally would be to let the patient experience more comfort and lesser pain. Continue reading...
Proven Lupus Treatment By Dr Gary Levin Summary
Contents: Ebook
Author: Dr. Gary M. Levin
Official Website: www.drgaryslupustreatment.org
Price: $47.99
My Proven Lupus Treatment By Dr Gary Levin Review
Recently several visitors of websites have asked me about this ebook, which is being advertised quite widely across the Internet. So I decided to buy a copy myself to figure out what all the fuss was about.
My opinion on this e-book is, if you do not have this e-book in your collection, your collection is incomplete. I have no regrets for purchasing this.
Acute cutaneous lupus erythematosus
Acute cutaneous lupus erythematosus (ACLE) usually occurs in association with systemic manifestations preceding by weeks or months the onset of a multisystem disease (Watanabe and Tsuchida, There are localized and generalized manifestations of ACLE (Costner et al., 2003 Fabbri et al., 2003). The localized form commonly presents as the classic malar rash'' or ''butterfly rash'' on the central portion of the face and may only affect the skin transiently. Therefore, at the onset of disease, the patient may mistake this rash for sunburn. It usually begins with small, discrete erythematous macules and papules, occasionally associated with fine scales and gradually becomes confluent and hyperkeratotic. Facial swelling may be severe in some patients with ACLE however, it mostly disappears without scarring and pigmentation (Norden et al., 1993 Yell et al., 1996). Similar lesions have also been found to occur on the forehead, the V-area of the neck, the upper limbs, and the trunk. In addition,...
Photosensitivity in Lupus Erythematosus
Lupus erythematosus (LE) represents an autoimmune disease with great clinical variability in which photosensitivity is a common feature for all forms and subsets. Cutaneous LE lesions often arise in sun-exposed areas and it is well reported and recognized that sun exposure may also exacerbate or induce systemic manifestations of this disease (Dubois and Tuffanelli, 1964 Nived et al., 1993 White and Rosen, 2003). The original concept of photosensitivity in LE dates back to the first description by Cazenave (1851) and early observations since the beginning of the 19th century, where the role of environmental factors were related to disease activity and even induction of the disease. Of the different external factors that have detrimental effects on disease activity, the sun's radiation has been best studied. Hutchinson (1888) reported in his Harveian Lectures on Lupus, that patients with LE did not tolerate the sun. The term ''Lupus erythematosus subacutus'' was first described by Fuhs...
Is Cd20 Expressed On Lupus
Therapy to patients with type III and IV lupus nephritis. Using rituximab in combination with steroids, 8 out of 10 patients responded at least partially after 2 months (median). Analysis of lymphocyte subsets in these patients revealed a prompt and clear reduction of T-lymphocyte activation, reflected by a decrease of surface expression of CD40L, CD69, and HLA-DR on CD4 + lymphocytes. These data suggest that B cells promote autoimmunity in humans by directly influencing T cells and are important in further understanding the pathophysiological process in SLE. The downregulation of CD40 and CD80 on B cells during treatment of SLE patients support this hypothesis (Tokunaga et al., 2005). Interestingly, Anolik et al. (2004) described that a specific B-cell depletion therapy with rituximab persistently improved abnormalities in B-cell homeostasis and tolerance. However, randomized controlled trials are urgently needed to confirm the excellent efficacy and safety profile of rituximab and...
Lupus Erythematosus
A premenstrual exacerbation of the cutaneous manifestations of lupus erythema-tosus (LE) was described in 25 of patients with systemic LE (34) and in 13 to 16 of patients with discoid LE (34,35). There are several indications that estrogen is an important cofactor for the development or exacerbation of LE. This is corroborated by the facts that the disorder affects females predominantly, that it is well known that estrogen-containing oral contraceptives may cause an exacerbation, as well as by the described association of LE with Klinefelter syndrome. In an in vitro study, the administration of estrogen was shown to lead to an upregulation of the binding capacity of antiRo SSA antibodies to keratinocytes (34).
Differential diagnosis
As far as pSS cutaneous involvement is concerned, cutaneous xerosis is an extraordinarily common problem, especially in the elderly, affecting at least 75 of the population aged 64 and older. Moreover, besides from elderly xerosis, pSS xerosis has also to be differentiated from dry skin secondary to underlying malignancy, renal insufficiency, obstructive biliary disease, hypothyroid-ism and idiopathic conditions (Vivino, 2001). Cutaneous vasculitis differential diagnosis includes both secondary vasculitis, due to infective agents, drugs or malignancies, and primary systemic vasculitis (mainly Mixed Crioglobulinaemia) (Gonzalez-Gay et al., 2003). Finally, annular erythema has to be differentiated from sub acute cutaneous lupus erythematosus (Katayama et al., 1991).
Calcineurin inhibitors
Topical tacrolimus is licensed for the treatment of moderate and severe atopic eczema in children (0.03 ) and adults (0.1 ) and, more recently, it has also been applied to other inflammatory dermatoses such as contact dermatitis, erosive lichen ruber planus, steroid-induced rosacea, pyoderma gangrenosum, vitiligo, and psoriasis (Assmann and Ruzicka, 2002 Gupta et al., 2002 Nasr, 2000). In single case reports, topical tacrolimus has also been shown to be effective in treating cutaneous lupus erythematosus (CLE). According to
LEspecific immunomodulation
Handled properly and, instead, localize to organs such as the kidneys. This results in various degrees of cellular proliferation, inflammation, and fibrosis leading in some patients to renal failure. Numerous clinical studies have investigated anti-dsDNA antibodies and their relationship to flare and lupus nephritis. Experiments in mice have confirmed the association between anti-DNA antibodies and lupus nephritis Administration of these antibodies to non-autoimmune mice has been shown to produce nephritis, and transgenic mice expressing a secreted form of an anti-DNA antibody develop lupus nephritis.
Differential diagnosis of papulosquamous SCLE
Chronic cutaneous lupus erythematosus The non-scaling pattern of early CCLE lesion presents as an erythematous plaque, sharply demarcated, with minimal scaling. Lupus tumidus, in which the papular component is predominant, can be considered as an extreme of the spectrum of the non-scaling pattern of CCLE manifestations. The diseases, which we may consider in differential diagnosis with the non-scaling pattern of early CCLE, are polymorphic light eruption, Jessner's benign lymphocytic infiltration of the skin, lympho-cytoma cutis, granuloma faciale, pernio (chilblain), and lupus pernio (sarcoidosis). The same diseases may also be considered in the differential diagnosis with tumid LE. Some CCLE patients may develop chilblain lesions on the extremities that evolve to form characteristic discoid LE (DLE) plaques, with a typical clinical appearance and a diagnostic pathology, for which the term 'chilblain lupus' or 'perniotic LE' has been proposed. This phenomenon might represent a...
Differential diagnosis of localized ACLE
The diseases, which we may consider in the differential diagnosis with localized ACLE, are acne rosacea, contact dermatitis and photodermatitis, seborrheic dermatitis, dermatomyositis, erysipelas, and delusion of lupus. 2.3.7. Delusion of lupus vs ACLE Delusional beliefs of having a butterfly rash occasionally induce some otherwise healthy subjects to ask for a rheumatological consultation (Fig. 6). In these cases, the differential diagnosis is easier than convincing the patient and sometimes the relatives that share the same delusional beliefs. Figure 6. Delusion of lupus slight erythema on the malar areas in a perfectly healthy subject with delusional beliefs. Figure 6. Delusion of lupus slight erythema on the malar areas in a perfectly healthy subject with delusional beliefs. DIF IgM and C3 around blood vessels in the superficial dermis and C3 along the dermo-epidermal junction can be present in erythema multiforme as compared to the lesional lupus band test observed in SLE. In...
Detection of antiphospholipid antibodies aPL in dermatology
Although new tests have become available, determination of lupus anticoagulant LAC and measurement of anticardiolipin antibodies aCL by Alarcon-Segovia, D., Delez , M., Oria, C.V., et al. 1989. Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus. A prospective analysis of 500 consecutive patients. Medicine 68, 353. Alarcon-Segovia, D., Perez-Vazquez, M.E., Villa, A.R., et al. 1992. Preliminary classification criteria for the antiphospholipid syndrome within systemic lupus erythematosus. Semin. Arthritis Rheum. 21, 275. Asherson, R.A., Derksen, R.H.W.M., Harris, E.N., et al. 1986. Large vessel occlusion and gangrene in systemic lupus ery-thematosus and lupus-like disease a report of 6 cases. J. Rheumatol. 13, 740. systemic lupus erythematosus. Scand. J. Rheumatol. 30, 235. Black, M.M., Hudson, P.M. 1976. Atrophie blanche lesions closely resembling malignant atrophic papulosis (Degos' disease) in systemic lupus erythematosus. Br. J. Dermatol....
Dermatologie aspects of Antiphospholipid Antibody Syndrome
The first definition of the antiphospholipid antibody syndrome (APS) described recurrent arterial and venous thrombosis and miscarriages in association with positive tests for the lupus anticoagulant, antibodies to negatively charged phospholipids (mainly cardiolipin) and to one of the bodies natural anticoagulants, a glycoprotein (B2GP1) (Harris et al., 1987). These remain the leading clinical features of this syndrome although its spectrum has broadened and has been expanded considerably over the last 15 years (Asherson and Cervera, 1992). Among these, a wide variety of dermatologic manifestations have been reported (Table 1) (Frances et al., 1996). Their clinical significance is highly variable and their management depends on their clinical aggressivity and the presence of other APS manifestations requiring therapeutic intervention. was evaluated systematically by the attending physicians and confirmed by a senior dermatologist. Dermatologie manifestations were present in 49 of our...
Diagnostic investigations and differential diagnoses
When cutaneous signs are associated with general symptoms and or other organ or system involvement of vasculitis, differential diagnoses are primarily other systemic diseases, like systemic lupus erythematosus, and secondary vasculitides, attributed to infections, neoplasia, hematologic malignancies or drugs. Indeed, many drugs have been reported to be potential causative agents of vasculitis (Table 5). Differential diagnoses of isolated purpuric lesions are numerous and relatively easy to make (thrombotic and or thrombocytope-nic purpuras idiopathic thrombocytopenic purpura, disseminated intravascular coagulopathy, thrombopathies vascular purpuras, with exclusion of vasculitides Ehlers-Danlos disease, scorbut, amyloidosis, Bateman's purpura, etc.). Embolic or atheromatous thromboses should also be ruled out when confronted with isolated distal necrosis or necrotic purpura. McDuffie's hypo-complementemic urticarial vasculitis is a rare systemic disease, characterized by the presence...
Agents targeting Tcells
Since T-helper cells may contribute directly to cutaneous tissue damage in LE by stimulating both macrophages and cytotoxic, specific inhibition of the T-helper cells using anti-CD4 was considered as a suitable approach to suppress disease activity (Owen and Harrison, 2000). Therefore, a recombinant chimeric CD4 monoclonal antibody (cM-T412) was investigated in clinical trials for its efficacy in the treatment of LE (Prinz et al., 1996). Treatment of five patients with chronic discoid LE including two patients with systemic involvement resulted in an immediate improvement in the skin lesions. Moreover, proteinuria as an index of lupus nephropathy was fully resolved and the antibody was well tolerated. Further controlled clinical trials are required to prove these very promising though preliminary results.
The Skin as an Immunologic Organ
States (e.g., allergic contact dermatitis, lupus erythematosus) thanks to the expression of specific chemokines on the surface of dermal endothelial cells. Dendritic cells are not only involved in the initiation of protective or immunopathologic immune responses, but also in the induction of immune tolerance. A low-grade migration of immature dendritic cells from the skin to the regional lymph nodes may indeed favour the activation of these T regulatory cells (Cavani et al., 2005).
The validation process
And the validation has not been published. In its current form, the instrument measures the degree of disease activity of extra-muscular organ systems and muscle. It is a combined tool that includes the myositis disease activity assessment visual analogue scales (MYOACT) and the myositis intention to treat activity index (MITAX). The MYOACT is modified from the vasculitis activity index (VAI) (Whiting-O'Keefe et al., 1999). The VAI grades nine presentations of vasculitis on a visual analogue scale, while the MYOACT grades the activity of a variety of signs and symptoms of myositis, among them the skin, on a 10-cm visual analogue scale. The other component of the assessment of each element of activity in the MDAAT is the MITAX. The MITAX is modified from the British Isle Lupus Assessment Group (BILAG) approach to assess disease activity in lupus (Hay et al., 1993). The MITAX is composed of a series of organ-specific questions relating to the presence or absence of the clinical feature...
Riccardo Rondinonea Stefania Banob Luca Iaccarinoa Andrea Doriaa
Lupus erythematosus (LE) is a multisystemic autoimmune disease that can occur with a wide spectrum of clinical manifestations. The skin is frequently involved, either as an isolated finding, i.e. when no other sign or symptom of systemic involvement can be disclosed, or as a part of a complex syndrome with multiple organ involvement. 2. Acute cutaneous lupus erythematosus
Clinical manifestations
Dermatomyositis occurs in both children and adults. It is a distinct clinical entity identified by a characteristic rash accompanying or, more often, preceding the muscle weakness. The skin manifestations include a heliotrope rash (blue-purple discoloration) on the upper eyelids with edema, a flat red rash on the face and upper trunk, and erythema of the knuckles with a raised violaceous scaly eruption (Gottron rash) (Dalakas 1990, 1991 Karpati and Carpenter, 1993 Engel et al., 1994 Dalakas and Hohlfeld, 2003). The initial erythematous lesions may result in scaling of the skin accompanied by pigmentation and depigmentation, giving at times a shiny appearance. In contrast to systemic lupus erythematosus, in which the phalanges are involved and the knuckles are spared, the erythema of DM spares the phalanges. The erythematous rash can also occur on other body surfaces, including the knees, elbows, malleoli, neck, and anterior chest (often in a V sign), or back and shoulders (shawl...
Other biological compounds
CTLA-4 is expressed on the surface of a subpopulation of activated T-lymphocytes and binds with high affinity to molecules of the B7 family that are present on B-cells and antigen-presenting cells. CTLA-4Ig is a fusion protein of the extracellular domain of CTLA-4 with the Fc portion of IgG1, which serves as a soluble receptor. Therefore, this molecule prevents CTLA-4 B7 interaction by blocking T-cell activation and T-cell-dependent B-cell functions in vivo. In animal studies, treatment of NZB W mice resulted in an improved survival rate as well as regression of nephritis (Finck et al., 1994). Clinical studies with CTLA-4Ig in patients with lupus nephritis are being initiated and one compound (BMS-188667) currently is investigated in clinical trials for patients with RA and psoriasis. Preliminary data indicate that treatment with CTLA-4 Ig appears to be an effective therapy for psoriasis and atopic eczema (Abrams et al., 1999 Najafian and Sayegh, 2000 Davenport et al., 2002 Davidson...
Separate measurements of disease activity and damage
The validation of the CLASI is described in detail elsewhere (Albrecht et al., 2005). This process has confirmed content validity. Construct validity is assessed by comparing the instrument to the other outcome instruments for cutaneous lupus. These do not exist, but the measures used in the SLE instruments available correlate with the CLASI. We did not assess criterion validity because the reason for the development of the instrument was that there was no measurement available. Reliability studies demonstrated an intraclass correlation coefficient (ICC) for inter-rater reliability of 0.86 for the activity score 95 confidence interval (CI) 0.73-0.99 and of 0.92 for the damage score (95 CI 0.85-1.00). The Spearman's Rho for in-tra-rater reliability for the activity score was 0.96 Select the score in each anatomical location that describes the most severely affected cutaneous lupus-associated lesion Albrecht, J., Taylor, L., Berlin, J., et al. 2005. The CLASI (Cutaneous LE Disease Area...
The etiology of SSc still remains obscure. Certain features like lymphocytic infiltration in the skin, antinuclear antibodies, and the occurrence of overlap syndromes with lupus erythematodes, der-matomyositis or Sjogren's syndrome point toward an autoimmune pathogenesis. Several disease models hypothesize, that genetically predisposed
Mycophenolate mofetil
Mycophenolate mofetil (MMF) was initially evaluated in RA and several years later also licensed for the treatment of organ transplantation. Because MMF inhibits specifically T- and B-lymphocyte proliferation by interfering with the inosine monophosphate dehydrogenase, it has emerged as an alternative in SLE mainly for patients refractory to other treatments. The growing interest on MMF in SLE is reflected by a supplement of the journal 'Lupus' to this drug (Hughes and D'Cruz, 2005). In recent years, MMF is mostly described for the treatment of lupus nephritis. Chan et al. (2004) reported a comparable response to oral cyclophosphamide however, long-term follow-up of the small number of patients indicated a high number of relapses. The still not fully published study comparing MMF with the protocol of the National Institute of Health by Ginzler et al. (2003) indicates a higher remission rate using MMF in type III-V lupus nephritis over 6 months. Unfortunately, follow-up data of this...
Ciclosporin A
One of the first new immunosuppressive agents was ciclosporin (CSA), which is licensed and mostly used in organ transplantation. Although CSA has shown promising results in various diseases with disturbed immunoregulation, controlled studies in SLE are limited after nearly 20 years of experience. In open labelled trials, CSA is mostly well tolerated and reasons for discontinuation are side effects, such as hypertension, tremor, and ne-phrotoxicity. However, in lupus nephritis the antiprotein uric effect of CSA seems to be favourable, especially in type V nephritis. The largest and longest experience in lupus nephritis is documented by Dostal et al. (1998) reporting a clear reduction in proteinuria and disease activity with a complete remission in 5 of 11 patients of a group suffering mostly from nephrotic syndrome. The same authors presented data of response to CSA in patients with lupus nephritis refractory to cyclophosphamide and showed similar renal outcome comparing both drugs in...
Richard D Sontheimer
In the 1960-1970s, the study of human lupus ery-thematosus (LE) was undergoing a revolution resulting from the description and characterization of various autoantibody-autoantigen systems as disease markers (e.g., Ro SS-A, La SS-B, U1RNP, Sm).1 That such autoantibody systems were found to be associated with specific clinical features of LE and associated rheumatic diseases led to the idea of subsetting LE patients on the basis of shared clinical, pathological, laboratory, and immunogenetic findings (Urowitz, 1977 Provost, 1979). Today, sub-phenotyping would be a more modern designation for the exercise of ''sub-setting'' (Stewart, 2002). One example would be the increased risk of lupus nephritis in LE patients found to have high levels of double-stranded DNA autoantibody and low levels of complement (C3, C4, CH-50). Another example would be mixed connective tissue disease In the early 1970s, Dr. James N. Gilliam in the Divisions of Dermatology and Rheumatology at UT Southwestern...
Localization and features of cutaneous lesions associated with joints and gastro-intestinal symptoms are very suggestive of HSP diagnosis. However, several other forms of leucocytoclastic vasculitis such as acute infantile haemorragic oedema (AIHE), hypersensitivity vasculitis, lupus erythe-matosus (LE), Wegener's disease and microscopic polyangiitis (MPA) can have a similar clinical presentation. None of the circulating IgA abnormalities described above are specific or constant. If specific immunological serological parameters can be used to differentiate HSP from LE, Wegener's disease and MPA, this is not the case for hyper-sensitivity vasculitis and AIHE. The AIHE is a rare cutaneous leucocytoclastic vasculitis generally without IgA deposits, clinically characterized by a symptom triad of fever, large purpuric skin lesions and oedema of hands, feet and face and taking place before the age of two (Caksen et al., 2002). It is a benign condition, which is confined to the skin and...
Deoxyspergualin (DSG) is a synthetic derivate of spergualin, originally isolated from Bacillus later-osporus, and licensed for reverse graft rejection in some countries. It is proven to be effective in animal models, such as experimental autoimmune encephalomyelitis and murine lupus. The precise mode of action is not known, but in vitro-studies indicate blocking of cell cycle progression in effector T cells following antigen stimulation and inhibition in the production of interferon gamma. Experiences in humans are limited and, in a few patients with primary vasculitis, DSG exhibited promising results. Actually, DSG is tested in a phase II III trial in moderate SLE.
Furthermore, abatacept was successfully applied to various lupus mouse models resulting in an improvement of survival and proteinuria however, data of patients with SLE are missing. A phase II trail is ongoing. Another costimulatory molecule, CD137, was successfully blocked in murine lupus models, and anti-CD80 (anti-B7) showed a moderate effect in treating patients with psoriasis.
Activation of complement induces the release of cytokines and chemokines, which, in turn, upreg-ulate the expression VCAM-I and ICAM-I on the endothelial cells (Stein and Dalakas, 1993). These molecules serve as ligands for the integrins VLA-4, LFA-I, and Mac-I expressed on T cells and facilitate their exit through the blood vessel wall to the perimysial and endomysial spaces. Various che-mokines have been upregulated at the protein and mRNA level (De Bleecker et al., 2002 Raju et al., 2003 Confalonieri et al., 2000). Immunophenoty-pic analysis of the lymphocytic infiltrates demonstrates B cells, CD4+ cells and plasmacytoid and dendritic cells in the perimysial and perivascular regions, supporting the view that a humoralmediated mechanism plays the major role in the disease. Other molecules upregulated in DM include TGF-beta (Amemiya et al., 2000) and (in the perifascicular regions) the cathepsins and STAT-I, probably triggered by interferon-gamma (Gallardo et al., 2001). After...
Selection and Interpretation of Laboratory Results
Antinuclear antibody and anti-DNA antibody titers are obtained to screen for collagen vascular disease, usually lupus. Low serum C4 concentrations reflect activation of the classical complement pathway, and C3 is decreased when either the classical or alternative pathway is activated. Such activation is most common in lupus or membranoproliferative
Project Title Fine Specificity Of Scleroderma Autoantibodies
Progressive fibrosis of specific target organs, such as the skin, lung, heart, gastrointestinal tract, and kidney. Although the underlying pathophysiology of this disorder remains an enigma, the presence of antinuclear antibodies in scleroderma patients is nearly universal. Targets of these autoantibodies include topoisomerase 1 (Scl-70), nuclear ribonucleoproteins (nRNP), centromere, PM-Scl, and Ku. Anti-topoisomerase-1 (topo-1) autoantibodies are quite specific for scleroderma. and are present in precipitating levels in 20-40 of patients. Anti-topo 1 is associated with diffuse skin thickening, lung involvement, and the development of lung, colon, and brain cancer. Scleroderma patients with anti-nRNP autoantibodies may have a more cutaneous form of the disease and universally suffer from Raynaud's phenomenon. Over the past decade we have extensively characterized the immunochemistry of lupus autoantigens. These previous studies provide the technical background for this proposal....
Cigarettes and the brain
Doctors usually diagnose the condition by excluding other illnesses with similar symptoms. As yet, there is no indicator or diagnostic test that can clearly identify the disorder. Overlapping symptoms can occur with several diseases, such as fibromyalgia, Gulf War illnesses, and multiple chemical sensitivities. Lupus, hypothyroidism, and Lyme disease also have similar symptoms and will need to be ruled out when making a diagnosis.
Cyclobut G See lobucavir
Cyclophosphamide (CY) An immunosuppressive drug that at high doses has been used in cancer chemotherapy regimens. In low doses, the drug has well-documented immunomodulatory properties and has been used to treat several immune disorders, including lupus and Wegener's granulomato-sis. In people with HIV, cyclosphosphamide is most commonly used in combination therapy for AIDS-related lymphoma. CY has a greater suppressive effect on b cells than on t cells, and CD8 cells are more sensitive to the drug than other T cell subsets.
Solute carrier family 22 organic cation transporter member 4 SLC22A4 and member 5 SLC22A5
As with PADI4, we initially identified RA-associated SNPs in a LD segment containing SLC22A4 and SLC22A5. Further dense-LD mapping identified RA-associated SNPs (OR 2.0) in the intronic region of SLC22A4 that disrupts the RUNX1-binding sequence 14 . Allele-specific effects of RUNX1 binding on SLC22A4 expression seem to produce RA-susceptibility as in the case with PDCD1 for systemic lupus erythematosus 47 and SLC9A3R1 or NAT9 for psoriasis 48, 49 .
Suicide and Medical Disorders
Medical disorders associated with an elevated risk of suicide are AIDS, cancer (especially head and neck), Huntington disease, multiple sclerosis, peptic ulcer disease, end-stage renal disease, spinal cord injury, and systemic lupus erythematosus. Any serious medical illness can raise the risk of suicide in elderly Caucasian men. In most cases, suicide in the context of a medical disorder occurs in conjunction with a depressive disorder or a history of alcohol abuse, or both.
Physiopathology and Risk Factors
Nella occurs, but they are not directly risk factors of en-dovascular infection such as aortitis. They are immunodeficiency, hypoacidity and gastric atrophy, long course antacid treatment, deterioration of endogenous digestive flora, extreme age, underlying malignancy, rheumato-logic inflammatory diseases and lupus erythematosus HIV infection with AIDS 76, 81 . In the new-born babies and in patients suffering from AIDS, which are two situations with risk of nontyphoid Salmonella bactere-mia, endovascular infection never occurs because of the lack of the primordial risk factor of vascular attack, which is atherosclerosis.
Young Woman with Postpartum Cerebral Venous Thrombosis and Abnormal Coagulation Tests
Lupus anticoagulant testing However, 10 weeks later, the patient presented with pleuritic chest pain. A spiral computed tomography scan and a ventilation-perfusion scan were indicative of pulmonary embolism. Admission laboratory studies showed that the PT-INR was not therapeutic (1.4), the aPTT remained prolonged, and the Staclot-LA test remained abnormal with a A value of 20.6 s (normal less than 9 s) indicative of the persistence of a lupus anticoagulant.
The Antiphospholipid Syndrome
Primary antiphospholipid syndrome refers to patients with the syndrome who do not have any other rheumatological or autoimmune conditions such as lupus erythematosus. Associated (but not defining) conditions include thrombocytopenia, vasculitic rashes, arthralgias, dermal necrosis of digits, livedo reticularis, and pulmonary hypertension. A thrombotic cause of these additional manifestations is unlikely since anticoagulant treatment does not result in a remission of these complaints. The presence of APL antibodies can be detected by either a phospholipid-dependent prolongation of a coagulation test lupus anticoagulant (LAC) or as anticardiolipin antibodies (ACA) in a b2-glycoprotein I (b2-GPI)-dependent enzyme-linked immunosorbent assay (ELISA). LAC activity and ACA are closely related but not identical. Patients should be tested with both types of assays (immunologic and clot-based) to rule out the diagnosis of antiphospholipid syndrome in a patient with a clinical presentation...
Diagnosis of Antiphospholipid Syndrome
Criteria for the definite diagnosis of APS were agreed on at an international workshop in 1999 and recently updated in 2005. These Sapporo criteria require at least one clinical criterium (vascular thrombosis or pregnancy-related morbidity (see Table 63.1) and one laboratory criterion (anticardiolipin antibodies isotype IgG or IgM at moderate or high levels, i.e., greater than 20 GPL or MPL units or a lupus anticoagulant (see Table 63.2). on two or more occasions separated by at least 12 weeks Lupus anticoagulant detected in the blood on two or more occasions separated by at least 6 weeks International Society of Thrombosis and Haemostasis criteria for lupus anticoagulant include Prolongation of a phospholipid dependent screening assay (e.g., aPTT, dilute prothrombin time,
Treatment of Antiphospholipid Antibody Syndrome
The optimal duration of anticoagulation for prevention of recurrent thrombosis in patients with APL antibodies is unknown. The risk of recurrence appears to peak in the first 6 months after discontinuation of anticoagulation, and is higher for patients with antiphospholipid antibodies compared to patients who are antibody-negative. Retrospective studies report recurrence rates as high as 53-69 . Therefore, the general consensus is to anticoagulate patients with APS and venous thrombosis indefinitely. It is unknown whether anticoagulation can be discontinued in patients whose lupus anticoagulant and or ACA testing has become negative, or if the only laboratory finding is a persistent low-titer ACA. Therefore, indefinite anticoagulation is recommended.
Pathophysiology Of
Occasional coexistence of pancreatitis with other autoimmune diseases suggests that there may be common target antigens in the pancreas and other exocrine organs such as the salivary gland, biliary tract, and renal tubules. We observed that several autoantibodies such as antinuclear antibody (ANA), antilactoferrin antibody (ALF), anticarbonic anhydrase-II antibody (ACA-II), rheumatoid factor, and antismooth muscle antibody were frequently detected in patients with AIP. LF, a nonenzymatic protein, is also detected in the various human tissues, including the lactating breast bronchial, salivary, and gastric glands and the pancreatic acinus.19 The high prevalence of these antibodies suggests that CA-II and LF may be the candidates for the target antigens in AIP. However, it is noted that these antibodies are not necessarily specific for AIP because ACA-II can be detected in some patients with SjS or systemic lupus erythematosus and ALF in ulcerative colitis or PSC.
Woman with a Rash and Lower Extremity Pain
The patient developed anorexia and lower extremity pain with weakness, nausea, and vomiting over the next week. On presentation to the emergency room, she also complained of fatigue, suprapubic pain, and fullness. The history was remarkable for frequent urinary tract infections over the prior 6 months, but no prior chronic health issues, surgeries, or pregnancies. Placement of a urinary catheter produced 1 L of clear output she was thus admitted with urinary retention and severe pain of the lower extremities. Further questioning revealed that the patient was involved in a long-term monogamous relationship (which included unprotected intercourse), that she had a cousin with lupus, that she smokes a pack per day, and that she had no known drug allergies. The admitting hospitalist consulted a rheumatologist for a possible diagnosis of systemic lupus erythematosus. Review of the patient's history and physical examination by the rheumatologist found that she had no evidence of current or...
Myositis and Myopathy
Hydroxychloroquine and chloroquine, anti-malarial drugs that are also used to treat systemic lupus erythematosus and RA, can rarely cause muscle disease, but this is not usually associated with much inflammation. The commonest symptom is weakness affecting proximal muscles such as the thigh and shoulder, without elevation of muscle enzymes. Even less common is inflammation of the muscles of the heart, cardiomyopathy, which if severe can cause heart failure.
Neuropsychological Dissociations Between Visual Working Memory And Spatial Working Memory
The dissociation between visual- and location movement-based working memory gains support from the patterns of impairment observed in a number of individual case studies. Farah et al. (1988) reported patient L.H. who, as a result of a closed head injury in an automobile accident, suffered damage in both temporal occipital areas, in the right temporal lobe and in the right inferior frontal lobe. He performed well on tasks concerned with memory for locations and for pathways, such as letter rotation, 3-D form rotation, mental scanning, and recalling a recently described pathway, but was severely impaired in his ability to remember colours, the relative size of objects and shapes of States in the map of the USA. A similar case was reported more recently by Wilson et al. (1999). Their patient, L.E., was a professional sculptress who, following systemic lupus erythematosus, resulting in diffuse damage to both the cortex and the white matter, was unable to generate visual images of possible...
Genetic Susceptibilities And Resistance To Toxicants
Genetic susceptibilities exist to the chemically induced adverse effects of ultraviolet radiation and visible light, a condition known as photosensitivity. Porphyria, an abnormal extreme sensitivity to sunlight, can result from chemical exposure in genetically susceptible individuals. Lupus erythematosus, a heritable disease manifested by red, scaly skin patches, is characterized by abnormal sensitivity to ultraviolet radiation. Porphyrias in genetically susceptible individuals, which can be induced by chemicals such as hexachlorobenzene and dioxin, occur through the malfunction of enzymes involved in producing the porphyrin heme used in hemoglobin. This results in the accumulation of porphyrin precursors in the skin. Exposed to ultraviolet light at 400 to 410 nm, these precursors reach excited states (see Chapter 2), which may generate damaging free radicals through interaction with cellular macromolecules and O2. Phototoxicity can also be caused by xenobiotic substances either...
Definition of the Disease
Systemic lupus erythematosus is a chronic, inflammatory, often multisystem disorder characterized by humoral autoimmunity. Specific autoantibodies gradually accumulate for years prior to the onset of clinical disease,2 which reinforces data showing an increase in the concentration of autoantibodies as well as their epitope specificity preceding the diagnosis of SLE. Indeed, while self-reactive antibodies may be relatively common in the population, the prevailing wisdom indicates that antibodies must mature in their affinity for self-antigens before assuming a pathogenic role. The mechanisms responsible for systemic lupus erythematosus have not been well articulated, but likely represent a complex interplay of genetic and environmental factors that ultimately result in disease-causing autoantibodies. Recent studies report that lupus patients have elevated blood levels of interferon a (IFN-a), suggesting that this cytokine may be a component of the disease mechanism, and or a response...
Lung inflammation Pneumonia
Lupus anticoagulant An acquired coagulation inhibitor first noticed in patients with systemic lupus erythematosus but since found in association with other immune disorders, including HIV. It is typically silent, meaning it does not effect illnesses at all, but it may on occasion, paradoxically, cause excessive clotting.
Acquired Hypercoagulable Disorders
Lupus Anticoagulant Antiphospholipid Antibody Syndrome The term antiphospholipid syndrome was developed to describe the clinical manifestations of a hypercoagulable state associated with antiphospholipid antibodies. The most commonly identified antiphospholipid antibodies are lupus anticoagulant, anti-cardiolipin antibody, and anti-P2-glycoprotein I antibodies.21 This syndrome is divided into primary and secondary syndromes. The primary syndrome occurs in patients without associated autoimmune disorders and the secondary syndromes occur in patients with systemic lupus erythematosus and or other autoimmune disorders. The procoagulant effects of the antiphospholipid antibodies leading to thrombosis include inhibition of the activated protein C pathway, inhibition of antithrombin activity, inhibition of anticoagulant activity of P2-glycoprotein I, inhibition of fibrinolysis, potentiation of platelet activation, and enhanced platelet activation, among others.8,21 Antiphospholipid...
Transcutaneous immunization
The skin performs a complex defense function that may be described as immunological. The immunological environment of the skin, including the humoral and cellular components, is given the acronym SIS (skin immune system). Dysregulations of this system can manifest as immunodermatolog-ical diseases, including atopic eczema, psoriasis, cutaneous lupus erythematosus, scleroderma, and autoimmune bullous disease.40-42
Clinical Findings
Nephrotic patients should be evaluated for a skin rash, which would raise the possibility of collagen vascular diseases such as systemic lupus erythematosus, and also for fever, which would suggest that the patient may have either renal inflammation or intercurrent infection. Nephrotic patients are susceptible to bacterial infections, mostly pneumococcal, including otitis, pneumonia, or primary peritonitis (the latter is more common in children). The absence of fever, especially after initiation of corticosteroid treatment, does not rule out infection.
Specialists in neuroimmunology concentrate on patients with autoimmune neurologic disease, particularly multiple sclerosis. According to the AAN, roughly 350,000 to 500,000 people suffer from multiple sclerosis in the United States. The neuroimmunologist also evaluates and treats patient with other autoimmune neurologic problems, such as myasthenia gravis, lupus, and Sjogren disease. Due to the complexity of these diseases, neuroimmunologists are also knowledgeable in their complications, including depression, psychosis, spasticity, incontinence, sexual dysfunction, and pain.
Lockjaw See tetanus
Lupus An autoimmune disease in which a person's immune system mistakenly works against the body's own tissues. Systemic lupus erythematosus (SLE), the most common type of lupus, typically develops during the 20s, 30s, or 40s mbut about 15 percent to 17 percent of people with systemic lupus first notice symptoms during childhood or adolescence. Most of these are children 10 years or older it is extremely rare in children under five. Experts estimate that between 5,000 and 10,000 children in the United States have SLE. Children diagnosed with lupus often have been ill for a longer period and are more likely to have significant internal organ involvement than most adults with lupus. This may be because many children are not recognized as having early lupus until the disease has become worse. As a result children with lupus often are required to begin aggressive therapy soon after diagnosis. While lupus can be a severe and life-threatening disease, many children with lupus will do very...
Nephritic Syndrome
Rapidly progressive glomerulonephritis (RPGN) is a clinical syndrome with many causes. These may be divided into three groups postinfectious RPGN, RPGN associated with systemic disease, and idiopathic RPGN. The most common form occurring after infection is poststreptococcal. Common systemic diseases associated with RPGN include systemic lupus erythematosus, Wegener's granulomatosis, vasculitis, and Goodpasture's syndrome.1 The pulmonary findings of linear fluorescence along alveolar basement membranes confirm that this patient had Goodpasture's syndrome. Goodpasture's syndrome is associated with antibodies to a component of the a3 chain of type IV collagen preferentially expressed in basement membranes of pulmonary alveoli and renal glomeruli.2,3 This antibody explains the clinical picture of RPGN with associated pulmonary hemorrhage. In both organs there is an acute necrotizing inflammatory lesion resulting in loss of basement membrane integrity with subsequent hemorrhage.
Common descent
Dogs and wolves, for example, are different species because they are reproductively isolated, but they have countless other features in common and for this are classified in the same genus Canis (Canis familiaris and Canis lupus). In the same way, tigers and lions are two species of the genus Panthera (Panthera tigris and Panthera leo), as polar bears and grizzly bears are different species of the genus Ursus. Tigers and domestic cats, on the other hand, cannot be put in the same genus, but still have so many characters in common that they are classified, together with lions, in a single family (the Felidae). species tigris leo domesticus familiariaris lupus arctos maritimus melanoleuca species tigris leo domesticus familiariaris lupus arctos maritimus melanoleuca
Metabolic Disorders
Several other disorders of lipid metabolism have been reported that can lead to chylomicronemia or hypertriglyceridemia and are independent of the lipoprotein lipase system. They represent a significant risk factor for the development of pancreatitis when plasma triglyceride levels rise above 2000 mg dl. The incidence of such disorders is even higher than that of disorders in the lipoprotein lipase system and additional factors such as drug therapies including glucocorticoids, estrogens, diuretics or beta-adrenergic blockers, and also alcohol abuse or diabetes mellitus can contribute to a further increase of hypertriglyceridemia above the threshold level for developing pancreatitis. The most common familial disorders associated with chylomicronemia are Type I and Type V hyperlipopro-teinemias (according to Levy and Fredrickson) that comprise a diverse family of disorders with moderate to severe hypertriglyceridemia.8 A predisposition for increased plasma lipids is also found in...
The alchemists were always fascinated by antimony and one of their names for the metal, which they obtained by heating stibnite with iron powder, was regulus (king) of antimony or martial regulus (king of Mars) implying an impure form of regal gold. Needless to say, they never achieved their objective of converting one into the other, but the spin-off from their researches greatly added to the store of knowledge about antimony. The alchemists had another name for antimony, lupus metallorum (wolf of metals), based on its remarkable ability to alloy with other metals and change their character. The alchemists were probably the first to discover butter of antimony, which they got by heating the metal with corrosive sublimate. They purified the product and then heated it in a sealed vessel for several
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ADVENTURES IN FUTURELAND3 x 60' for Channel 4
TX September 2019
Comedian and film maker Jamali Maddix explores the wild west frontier of Sex, Fame and Money in the digital era. In Miami and Las Vegas he discovers a new breed of entrepreneurial performer providing bespoke personalised sex services for a price. In LA he meets children who have become global online celebrities. And in Puerto Rico he joins a Bitcoin billionaire and his followers who are trying to create a radical new community.
Presented by Jamali Maddix
Presented by Jamali Maddix
Assistant Producers Sarah Muhsen, Poppy Begum and Evie Buckley
Filmed and Directed by David McConnell and Lauren Jacobs
Executive Producer Jaimie D'Cruz

subset: commoncrawl


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- This article is about the Nordic Museum in Stockholm. For the Nordic Museum in the Ballard district of Seattle, Washington see Nordic Museum (Seattle).
The Nordic Museum (Swedish: Nordiska museet) is a museum located on Djurgården, an island in central Stockholm, Sweden, dedicated to the cultural history and ethnography of Sweden from the early modern period (in Swedish history, it is said to begin in 1520) to the contemporary period. The museum was founded in the late 19th century by Artur Hazelius, who also founded the open-air museum Skansen. For long part of the museum, the institutions were made independent of each other in 1963.


text:
Marc Cuenco
Former teen magazine editor. Pop culture nerd. Runner. Follow him on Twitter @iamcram.
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Of all the topics I read about on Christian Case Making (apologetics) blogs, I seldom find anyone writing about leadership. But this aspect of the Christian life, while it is often overlooked, is critical to our success as Case Makers. When we think about what's required to be a good …Read More »
It's Better to Be Respected Than Liked
I had a discussion with one of my kids recently about the natural inclination we all have to be adored. Let's face it, we all want to be accepted, loved, admired and embraced; it's difficult when you find yourself on the "outside looking in", shunned or ignored by those who …Read More »


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Greetings! I'm Hampton, a digital artist & designer. I enjoy creating works of fantasy & mystery for book covers and other mediums.
• provided visual design and voiceover services to over 200 clients
• designed book covers, logos, album artwork, and commercial graphics
• provided front-end website development and Wordpress services
• recorded voiceovers for commercials, PSAs, and other audio projects
• designing logo and brand identities for restaurants and franchises located throughout New York
• creation of print and motion graphics for menus and other materials
• designed logo and branding identity concepts
• created illustrations and animations for point-of-sales graphics
• designed responsive web concepts from wireframes and
original graphics
• created social media graphics and animations for internal branding
• worked collaboratively with the head graphic designer to develop client brand materials, including logos, social media banners, and web design concepts
• conducted research on brand competitors and contributed to brand ideation
• worked collaboratively with the head designer and project manager to
provide branding services
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Christina Blake
Sixteen-year-old, Sapphire Serel wants more out of her life. She lacks a close relationship with her parents, who neglect to notice her and day after day, she feels as if she is drifting away from her once-close friends, Aria and her boyfriend, Jesse. Although, it isn't until people around the world start dying for no found reason that her life becomes exceptionally complicated. Her existence ... read more
The Legendary SoldierMajor Allana Guiver lost everything in the war. She lost her friends, she lost her troops, she lost her family and she lost her fiancee. She lost all this and more to defend humanity in its time of need. Then she was cryogenically frozen.The ViatosThey are a mysterious alien threat who appeared from the dark abyss. They claim to be humanity's salvation and plan to rid huma... read more
Charles Norman
A TALE YOU HAVE NEVER HEARD It's a story that has become legend. The burning bush. The plagues on Egypt. The parting of the Red Sea. The Ten Commandments.But before he was Moses, he was Kisil -- a wanderer, an almost-ordinary man, both doubting and driven. And before she was the wife of a prophet, she was Tzipporah -- the fierce, faithful woman who lent her wisdom and courage when his faltered... read more
Matt Casamassina
When 17-year-old Zephyr Rockwell wakes from a camping trip in the woods, he discovers that nearly everyone in the world has disappeared and most of the luxuries mankind maintained are already breaking down. What happened? Where did everybody go? Why is he still here?The boy soon embarks on a journey for answers and companionship in a new reality where great cities lay in ruins, food and water ... read more
Crystal Packard
What readers are saying . . . "A wonderful voracious read" "This book will absolutely sweep you away . . ." "A world-hopping, romantic, fantasy adventure!"How much would you risk for love? . . . .Everything? Seventeen-year-old Lily Harris is pretty sure she's going crazy. Weird things are happening. Scary things. A demented owl taunts her daylight hours, and her nights are filled with frighten... read more
Andrea Rose Washington
Sasha's lived a simple life, until her mother's secret came to light. Now, at the age of sixteen, Sasha learns that, not only has everything to that point been a lie, but now there's a hit squad after her. To escape their attackers, Sasha's mother, Jasmine, sacrifices herself so her daughter can escape. With her best friend Cassie in tow, and her mother branded a traitor to the crown Sasha mus... read more
Ali Abbas
Commander Raymond Burntwood of the Royal Navy has returned to England where he meets the reclusive heiress Lady Ariana Grayhart. After the scandal of a night spent dancing together, Ariana returns home to Northumberland. Raymond's superiors—seeking information about Ariana's father—dispatch the commander under the cover of courting the heiress. All is not as it seems in the Grayhart household.... read more
Ben Mariner
On a cube planet embroiled in magic, monsters, adventure, and sticky buns, a sinister plot unfolds that will join unlikely friends on a journey where the flow of time is variable and youth is at stake.Cubonia's most famous treasure hunter, Broderick Porter, has just been hired to steal a necklace from Queen Annelise's youngest daughter, Alexandra. For one so skilled, it should be an easy job. ... read more
Andrew Gibson
In the 22nd century, living beyond death has moved from science fiction to science fact. However, a casual onlooker, from another planet perhaps, would never know it because those who have been brought back to life have been pushed out into the margins of society. Though resurrecting the dead is a new concept, discriminating against an entire population of people is old hat.This bigoted attitu... read more
Kimbra Swain
The descendant of a Greek Titan, a reluctant shape shifter, and an angel's warning. The Agency's purpose coincides with its leader, Hyperion. As the father to the sun, the moon and the dawn, the Greek Titan endeavors along with his vast network to ensure the world keeps turning. Abigail Davenport, a descendant of the Titan and powerful magic wielder, must adapt the network she established befo... read more
Mia Archer
The good girl. The outlaw. A second chance at first love they can't ignore. An explosive romance more dangerous than they could ever imagine!It's been ten years since Mari last saw Robin Locke. Ten years since she put her hometown in the rear view mirror. Ten years of trying and failing to forget about her first love.Mari told herself she'd never move back home. She told herself she'd never ge... read more
K.F. Bradshaw
The people of Damea are no strangers to magic. They have wielded it for years - woven it into their societies and everyday lives. From powering marvelous cities, to building dazzling infrastructures to maintaining even the tiniest of farms, magic is the backbone of Damea. It is a part of them, it breathes with them. But the magic is dying, and taking Damea with it. With the land rapidly headin... read more
Tanya Dawson
One girl. Two bloodlines. One pledge to be made.When Olivia Whitby's mother vanishes, a cryptic letter left at her door leads her to a family she never knew – a family of Fae. But the secrets run even deeper and Olivia soon finds herself trapped amongst the power struggle between the Fae and the Sabean Vampires, whom she is thoroughly warned to stay away from. However, the possibility of findi... read more
J.M Clark
Twenty years ago, Jacob lost everything. Just as he was starting to figure out life as a college freshman,his world was suddenly shattered when a devastating illness destroyed the world he once knew and claimed the lives of everyone that mattered to him.Jacob and the other survivors of the pandemic were transported to the Palace Program. Housed ina quarantined modern facility, the Palace is a ... read more
Hali C. Broncucia
A viral epidemic has wiped out 99% of the world's population leaving scientist Heather Morgan to fight off thieves and scrounge for food and shelter near Denver, Colorado. When Heather befriends the young, naïve Jodi, she learns that a biotech company in San Francisco is rumored to have created a vaccine. Together, the women trek by foot to find the lab. After suffering a near-fatal attack, He... read more
Scorned by her family. Banished by her kind. Hunted by zealots.Where does an exiled Fairy Queen hide?A remote mountain cabin, the seedy underbelly of a metropolis, or an uninhabited island. All would be good choices, however, after hundreds of years on the run, the daughter of Oberon, King of the Wild Fairies, signs a binding contract with the zealots that hunt her. In exchange, they allow her... read more
Daniela Elana
Deep within Maricel's dreams a familiar set of iridescent eyes melt her heart and a melodic voice captivates her soul. Claudius an enigmatic Watcher haunts her dreams waiting to initiate contact. When a twenty-two year old actress moves to Los Angeles to star in a horror film, little does Maricel know she's been cast in one for real. For the past four years, Claudius has been there every time ... read more
Blaire Hammond
Centuries ago, on the planet Elixir, a new race was born. A race much stronger, and more powerful than they have ever known. A race trained to fight, to protect their world from those that lurk in the shadows. They are known as the Enchanted. But with good, comes evil. With the Enchanted, come the Wicked. And the Wicked will do all they can to seize power. There is a war brewing, and should it... read more
Dan Kemp
The year is 1890, and a small town mayor is trying to hold his community together, while seeking revenge for his wife's recent murder.The year is 1972, and a small time crook is in way over her head as a deal goes very wrong.The year is 2020, and a homicide detective is on the trail of a serial-killing vigilante.On the eve of the 2020 presidential election, these characters, their stories, and... read more
Diane Glen, April 2020
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Sci-fi and fantasy specialist with 400+ covers. Experience with 14 of the top 100 Amazon authors in SF&F & 100+ Bestselling Books.
I 'm a freelance graphic designer, specializing in book covers. Favorites genres? Anything "dark" and "grungy" suits my style!
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Women's Basketball Looks For Weekend Sweep
Jan. 31, 2003
CORVALLIS, Ore. -
Complete Release in PDF Format
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Saturday, Feb. 1, 2003
Arizona State at OSU
7 p.m. PST, Corvallis, OR
(Gill Coliseum)
Radio broadcast on KRKT 990
OREGON STATE BEAVERS (11-8 overall; 5-5 Pac-10)
G #10 Leilani Estavan, 5-7, Jr.,(11.6 ppg, 2.6 rpg, 5.1 apg.)
G #14 Jessica Jones, 5-8, So., (3.4 ppg, 2.7 rpg, 1.8 apg.)
G #24 Mandy Close, 5-11, Fr., (4.1 ppg, 2.3 rpg, 1.1 apg.)
F #45 Hollye Chapman, 6-2, Jr., (11.6 ppg, 5.9 rpg, 2.6 apg.)
C #42 Brina Chaney, 6-5, Jr., (8.8 ppg, 6.6 rpg, 2.5 bpg.)
ARIZONA STATE SUN DEVILS (12-7 overall; 4-6 Pac-10)
G #10 Kylan Loney, 5-7, So., (9.1 ppg, 1.4 rpg, 3.5 apg)
G #22 Jill Noe, 5-10, Fr., (15.0 ppg, 5.7 rpg, 3.2 apg.)
G #30 Carrie Buckner, 5-9, So., (7.3 ppg, 5.5 rpg, 1.4 apg.)
F #32 Amy Denson, 6-1, Fr.,(11.1 ppg, 6.5 rpg, 0.7 apg.)
F #54 Kristen Kovesdy, 6-3, Fr., (11.1 ppg, 6.5 rpg, 1.2 apg.)
A GLANCE AT ARIZONA STATE: Arizona State enters Saturday's game at Oregon State with a 12-7 overall record and 4-6 Pac-10 mark. The Sun Devils have lost three of their last four games and boast just a 1-4 record in conference road tilts. Three players reached double figures in scoring in ASU's 68-52 loss at Oregon on Thursday, but the Sun Devils committed 23 turnovers compared to just 15 by the Ducks. A pair of Oregon products led ASU to victory against rival Arizona last Thursday, as freshman Jill Noe of Wilsonville High School had 22 points and seven rebounds against the Wildcats and Corvallis product Carrie Buckner recorded a double-double with 10 points and 12 boards. Noe leads the squad in scoring with 15.0 points per game and is shooting 43-percent from the field and 82-percent from the free throw line. Another Oregon product, Amy Denson of Crater High, averages 11.1 points and 6.5 rebounds while post Kristen Kovesdy also adds 11.1 points and 6.5 boards. The youthful ASU squad starts three freshmen and two sophomores and has only one senior on its roster. The Sun Devils lead the Pac-10 in offensive rebounds per game (15.78).
STATISTICALLY SPEAKING: How Oregon State stacks up statistically with Arizona State:
OSU ASUPoints per game 58.2 67.8Points allowed per game 57.8 62.4Field goal percentage 40.2 41.73-pt field goal percent 26.0 33.9Free throw percentage 65.3 69.1Rebounds per game 37.6 37.4Assists per game 14.9 16.1Steals per game 7.6 10.9
BEAVERS AND SUN DEVILS SERIES NUMBERS: Oregon State leads the all-time series with Arizona State, 18-17, dating back to the 1983-84 season. The two teams split the last two seasons' meetings, with each squad earning victories on its home court. ASU has won nine of the last 12 games in the series but OSU has won two of the last four. Oregon State has won three consecutive games in Gill Coliseum. Head coach Judy Spoelstra has a 7-8 record against the Sun Devils.
LAST TIME OUT AGAINST ARIZONA STATE: Oregon State led by as many as five points in the opening half but Arizona State used a big second half run to knock off the Beavers, 70-58 on Jan. 2. The win was the seventh consecutive for ASU against OSU in Tempe. ASU went on an 11-4 run in the middle of the second half, helped in part by a pair of 3-pointers, to earn a 51-44 lead with just 6:43 remaining. The Beavers would get no closer than within four points the rest of the way. Freshman guard Casey Bunn led the squad with a then career-best 13 points on 5-of-8 shooting and pulled down five rebounds. Leilani Estavan also reached double figures in scoring with 12 points and Juleen Smith added 10. Junior post Brina Chaney hit 4-of-5 field goals for nine points while fellow post Hollye Chapman amassed a career-high six assists. Three Sun Devils reached double figures in scoring led by Wilsonville High grad Jill Noe's 23 points and 11 boards. Arizona State dominated the glass with a 40-24 rebounding edge, including a 15-8 advantage on the offensive boards.
INJURY UPDATE: Oregon State freshman guard Anita Rivera will miss the remainder of the season after tearing her ACL in a collision during the Jan. 11 game against California. Rivera saw action in 10 games for OSU and averaged just over one rebound per outing. Sophomore guard Juleen Smith has missed four consecutive contests while nursing an ongoing hamstring injury. Her return to the lineup is questionable for the remainder of the season. The 5-5 speedster has now missed eight games on the season due to the hamstring injury.
LOOKING BACK AT No. 24 ARIZONA: Leilani Estavan had 20 points, nine assists and six steals as Oregon State knocked off No. 24 Arizona 71-65 in overtime Thursday night. The victory was the first for OSU against a ranked opponent since defeating No. 22 Arizona State on Mar. 3, 2001. The win also marked the third straight for the Beavers against the Wildcats in Corvallis. Hollye Chapman buried 8-of-10 field goals and pulled down 11 rebounds for her sixth career double-double, while freshman Casey Bunn had her first double-double with 14 points and 10 boards. Freshman Shawntinice Polk led Arizona with 18 points and 11 rebounds. OSU trailed by six points (29-23) at the half but scored eight straight points to open the second frame. The back and forth second half saw neither team lead by more than five points. Oregon State finished the game shooting 48-percent from the field while Arizona hit 45-percent of its shots.
LOOKING BACK AT WASHINGTON: It was all Washington, as the Huskies rolled to a 82-56 victory against Oregon State on Jan. 25 in front of 5,964 fans at Bank of America Arena. UW led by as many as 29 points (68-39) with 8:03 remaining and held a 43-21 halftime advantage. Leilani Estavan scored a career-high 24 points for the Beavers on 9-of-18 shooting, including a 4-of-9 clip from 3-point range. Brina Chaney added eight points and Kristina Rukstelyte had four points and a team-high five rebounds. Four Husky players reached double figures in scoring with Emily Autrey and Giuliana Mendiola finishing with 13 each. Mendiola also dished out a career-high 13 assists. UW held a 43-26 rebounding advantage.
LOOKING BACK AT WASHINGTON STATE: Sophomore guard Jessica Jones buried four free throws in the final 13 seconds as Oregon State escaped with a 65-62 victory at Washington State on Jan. 23. The Cougars led by as many as 10 points (45-35) with 10:38 remaining in the game but the Beavers battled back to eventually knot the score at 49 behind a 3-pointer by Jones, who finished with a career-high 13 points and matched her career-best with seven rebounds. Hollye Chapman scored 10 of her 16 points in the final 3:28 and gave the Beavers the lead for good after converting an old-fashion 3-point play with just under one-minute in the game. All-told, the Cougars held the lead in the contest for 35 minutes and 50 seconds, but OSU had the advantage when the final buzzer sounded. Leilani Estavan also reached double figures in scoring for Oregon State with 12 points and dished out six assists. Bianca McCall led all players with 20 points and 11 rebounds for WSU. The loss was the 40th consecutive for the Cougars.
FAST FACT: Oregon State has swept the home series with the Arizona schools in two straight seasons.
FILL GILL: Tickets for Saturday's game against Arizona State can be purchased at the door for $1. Game-time is scheduled for 7 p.m. with the gates opening at 6 p.m.
BIG WIN: Oregon State's 71-65 overtime victory against No. 24 Arizona on Thursday night marked the first time the Beavers had topped a ranked opponent since knocking off No. 22 Arizona State on Mar. 3, 2001. Oregon State's 71 points against the Wildcats were the most for the Beavers this season. OSU's previous high-scoring game was 70 points in a 83-70 loss at Portland on Nov. 26. The Beavers suffered their worst loss of the season in Tucson earlier this year when the Wildcats ran away with a 72-44 victory.
GOOD THINGS COME IN TWOS: Junior post Hollye Chapman buried 8-of-10 field goals, including a perfect 3-for-3 clip from 3-point range, and pulled down 11 rebounds against No. 24 Arizona on Thursday. The double-double was the sixth of Chapman's career and her third this season. The Oregon City grad is shooting a team-best 41-percent (23-of-56) from 3-point range and has reached double figures in scoring in 11 games this season. Freshman Casey Bunn knocked down 6-of-8 field goals for 14 points and pulled down a career-high 10 rebounds, including five on the offensive glass, for her first career double-double. Bunn is shooting 50-percent (48-for-97) on the season - leading all the Beaver guards and ranking third best on the team. The Stayton, OR product is averaging 11.3 points and 7.3 rebounds over the last four games. On the year she averages 6.4 points and 3.7rebounds.
GOOD POINT: Junior Leilani Estavan scored a career-high 24 points on 9-of-18 shooting, including a 4-of-9 clip from 3-point range at University of Washington Jan. 25. The 5-7 guard followed that performance with 20 points, nine assists and six steals, while committing just one turnover against No. 24 Arizona on Thursday. Estavan has reached double figures in scoring in five straight games and in a team-high 13 contests on the year. Estavan currently ranks tied for first on the squad in scoring with 11.6 points per game. Her 5.1 assists and 2.1 steals lead the team.
HOME SWAT HOME: Junior post Brina Chaney has amassed 47 blocked shots on the season, 36 of which have come in games played in Corvallis. On the year, 54 of Oregon State's 81 blocked shots have occurred on Ralph Miller Court.
DID YOU KNOW: Freshman Mandy Close has made 17 consecutive appearances in the starting lineup...Forward Hollye Chapman ranks second on the team in assists with 50...Hollye Chapman has hit a team-high 23 3-point field goals....Oregon State is 7-0 when it leads at the half...The Beavers are 0-4 when tied at the half...Leilani Estavan has reached double figures in scoring in five consecutive games...Oregon State is 10-2 in games which it shoots better than its opponent...Brina Chaney leads the Pac-10 in blocked shots with 46 on the year and ranks 13th in the nation with 2.5 swats per game...Oregon State has blocked seven or more shots in five games this season...The Beavers entered the week ranked 1st in the Pac-10 and 32nd in the nation for scoring defense, holding their opponents to just 57.4 points per game.
PAC-10 TOURNAMENT: The 2002-03 season will conclude with the State Farm Pac-10 Women's Basketball Tournament to be played at the HP Pavilion in San Jose, CA on March 7-10. The tournament's winner will receive the Pac-10's automatic bid to the NCAA Tournament. Tickets may be purchased through the Oregon State ticket office at 1-800-GOBEAVS.
PACIFIC-10 CONFERENCE COACHES POLL: For the second consecutive year, Oregon State was tabbed to finish in seventh place in the 2002-03 Pacific-10 Conference race, as voted on by the Pac-10 coaches. The Beavers received 40 points in the voting, while Stanford, who went undefeated in conference play last season, was predicted to repeat as champion with 90 points and nine first place votes. OSU's 2001-02 fourth place finish was its highest since 1995-96, when the squad finished second.
CLOSING IN ON RECORDS: Junior post Brina Chaney currently ranks in 4th place in the OSU record book for blocked shots with 117 in her career. Chaney tied the OSU school record for blocked shots in a single game with eight swats against Oregon on Jan. 18. The 6-5 post needs just 12 more swats to move into sole possession of 3rd place in the record book and pass Tanya Mothershed's (1982-85) total of 128. Chaney has tallied five or most blocks in four different contests this season. Her 47 stuffs on the year are tied for fifth on the OSU single-season chart. Junior guard Leilani Estavan ranks in 8th place for assists in the OSU record book. The 5-7 guard has 410 career assists. Estavan needs 12 dishes to climb up the ladder to 7th place on the all-time list and pass Chelle Flamoe's (1986-89) total of 421. Estavan has tallied nine assists in two different contests this season.
STREAKS TO WATCH: Junior guard Leilani Estavan is the only Oregon State returning player to start all 32 games last season. Estavan closed out the 2000-01 campaign with eight straight starts, giving her a current streak of 59 consecutive appearances in the starting five.
IN GILL: The Beavers have won 74 of their last 115 (.643) games played at Gill Coliseum. Over the last nine seasons OSU is 90-45 in the friendly confines of Gill.
NON-CONFERENCE RECORD: Oregon State has an all-time non-conference record of 237-124 dating back to the 1976-77 season for a .657 percentage.
ON THE BENCH: Assistant coach Todd Corman returns for his second year on the Beaver bench after spending 10 seasons as the head coach at Loyola Marymount University and more recently, six years at the helm of Albertson College. Jualeah Woods enters her third year on the Oregon State staff, assuming second assistant coaching duties in July. Heath Alexander joins the coaching staff as an assistant coach after spending the 2001-02 season as director of operations. Mary Kincaid, a 14-year coaching veteran, joins the staff for her first year as operations director.
HEAD COACH JUDY SPOELSTRA: Judy Spoelstra has a record of 106-113 in her eight seasons at the helm for Oregon State. Spoelstra has recorded a 204-181 overall record while in her 14th season as a collegiate head coach, her first six being at Montana State. She picked up career win No. 200 against USC on Dec. 27, 2002. Spoelstra has led the Beavers to back-to-back postseason tournament appearances in the WNIT. At the conclusion of the 1999-00 season, Spoelstra was named Pacific-10 Conference Coach of the Year.
Pac-12 PlaylistTOMORROW | 7:00pm PTLive
Pac-12 PlaylistThu 4/2 | 7:00pm PTLive
Pac-12 PlaylistMon 4/6 | 7:00pm PTLive


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Delamode: Logistics
The Group's warehousing and logistics services are based in the UK, Romania and Bulgaria and comprise three core supply chain logistics businesses: Delamode Logistics UK; Delamode Logistics Romania; and Pall-Ex Romania, plus the recently acquired EMT business.
The Group provides end-to-end supply chain solutions for national clients which includes inbound logistics, storage solutions, eCommerce fulfilment and related services as well as "final mile" delivery. The activities tend to comprise of in-country, rather than cross-border services and include:
- Warehousing and logistics;
- E-commerce fulfilment;
- Storage solutions and related value-added activities;
- Domestic express palletised freight distribution;
- Collection of full truck load and part load transport services within national markets.
Delamode operates 9 multi-user warehouse facilities strategically located throughout Romania and services blue chip customers within a number of sectors, including technology, manufacturing, FMCG, automotive, agriculture, retail and commerce.
The UK warehousing and logistics division is based at the Group's leased facility in Braintree. The freight logistics warehousing operations of this facility have become more focused on e-commerce fulfilment which is seen by the Board as a key area for long-term growth.
Pall-Ex Romania
The Pall-Ex Romania business is a pallet delivery franchise which has been licensed to the Xpediator Group by the Pall-Ex group, leading UK based palletised freight network provider. The Pall-Ex concept operates on the basis of an express palletised freight distribution service which uses a pallet transport network of regional and central hubs to ensure all movements of goods are, as far as possible, with overnight full load transport.
The Pall-Ex Romania palletised freight network commenced trading in January 2012, transporting 868 pallets in its first month. Current volumes exceed 40,000 pallets per month and the Directors expect pallet delivery volumes to continue to rise. The average consignment size is 1.46 pallets, which can be distributed across Romania normally within 24 hours.
As a result of the success of Pall-Ex Romania, the Pall-Ex Group has recently awarded Xpediator the master franchise licences for both Hungary and Moldova.


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Players with little to no experience, seeking to develop basic skills, techniques, and game strategies.
This class is tailored for students with little to no experience playing tennis. Students will be playing with a ball that bounces lower and moves slower through the air, making it easier to hit at a comfortable height, while also providing more time between shots to prepare for the next ball. Players will be taught basic skills of the game, in addition to development an enjoyment for the sport.
This class will continue to use either red, orange, or green dot balls, as players continue to develop basic level technique and tactics. In this stage, players will start to incorporate simple footwork and movement around the court, in addition to having an introduction to game strategy. Players at this level will feel more at ease hitting the ball with more speed, accuracy, and consistency.
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Ideal for Students with some experience playing tennis, who obtain a basic understanding of the game, and are beginning to enter in novice to challenger level tournaments.
Students in this class will be playing with regular yellow balls. The class is for players who have had some experience playing tennis, and is able to rally with other students. At this stage, students are beginning to enter novice level tournaments, and will start to participate in more practice matches, to develop and improve their game
This next level of class is for those who are more familiar with match play, and are looking to learn different types of shots and footwork to expand their game. Students in this class will be doing more advanced drills as they learn to become a more well-rounded player. In this stage, juniors are expected to be able to play full length matches and incorporate skills they have learned during class, in a pressure environment.
Tournaments players holding at least two years of competitive experience, aspiring to develop and improve their game to progress to the next level.
Players in this class are participating in challenger-level tournaments, with at least two years of competitive match-play experience, and are more serious about advancing their game. Students will be conditioning to work on increasing their fitness level, as well as continuing to learn more on-court strategies and tactics. This class is designed to teach students to play and focus at a higher level, in order to start seeing better results in tournaments.
Juniors at this level are beginning to play open level tournaments, and have a greater intent and aspiration to progress their game to the next level. At this stage, classes will be held at a higher intensity level, while more conditioning and complex drills will be incorporated in the class. Students will learn more advanced strokes to add to their skill-set, as well as which style of play fits their preference and abilities best.
Intense tournament players with at least four years competitive experience, along with a USTA NorCal ranking to Register.
Student in this class are playing at the championship tournament levels, and have an official USTA Norcal ranking. Players in this class have already developed a style of play, and are seeking to improve their game to reach the top level. Classes will have an even greater concentration on fitness, as drills will proceed at a quicker pace, while incorporating a greater range of shots, and using a wider range of the court simultaneously.
This is our highest level of class, and is more players competing in national tournaments or looking to progress to play college tennis or the professional circuit. A large portion of this class will include conditioning, while players excel towards obtaining a solid grasp on the necessary footwork and technique needed in higher level, and broadening their match-play expertise. Students will be training at the upmost intensity level, working to increase their court agility, speed, power, endurance, and competitive mindset.
Here at Silicon Valley Tennis Academy we have the right combination of activities for the Adult population, with a blended mix of stretching and conditioning exercises (to help joints stay limber) and match play in competitive leagues (to retain your competitive edge!) Choose whichever program looks best to meet you interest, play like you mean it, and stay on for the buzzing social life afterwards. If you have questions, please email email@example.com!
Players will be grouped according to age and skill level.
Silicon Valley Tennis offers Bay Area residents a wide variety of Summer Programs at our Mountain View location for all levels. We welcome all levels from toddlers to adults and red ball to professionals. You can customize your classes by selecting from a variety of days/ times within each package.
No. of Lessons
Total Fee
Great Tennis Lessons with Coach Francisco
1 hour private lesson
12 Hours of one on one training with coach Francisco. Please contact him directly at 650 924 3085 to confirm the times
6 Hours of one on one training with coach Francisco. Please contact him directly at 650 924 3085 to confirm the times


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SUBEA SCD braided Hyperflex SCUBA octopus hose yellow neonSUBEA
From To
* From To
Product benefits
Technical Information
Length: 100 cm.
First-stage connection: 3/8 UNF male connection. Tighten with a 9/16 inch wrench (between European sizes 13 and 14).
Second-stage connection: 9/16 UNF female connection. Tighten with a 11/16 inch wrench (between European sizes 17 and 18).
The base of the hose is made from antimicrobial thermoplastic polyurethane (TPU) polyether.
Outer coating: braided nylon for greater strength and suppleness. Withstands more twisting than conventional rubber hoses. Prevents the feeling that the regulator is pulling on the mouth.
The MP (medium pressure) hose, also called LP (Low Pressure), conveys the expanded air from the tank (compressed at high pressure) through the first stage and to the second stage of the regulator. The conveyed air is usually at a pressure of between 8 and 10 bar.
To not overtighten the first stage. First stages are usually made of chrome-plated brass, a soft alloy. Overtightening can damage the first stage. The O-ring on the hose is used for watertightening purposes.
On the second-stage connection, there is a cylindrical male part inside with an O-ring for watertightness.
Use a silicone grease to lubricate the seals and increase their lifespan.
Repeated pressurisation of the regulator and external cracks will made the hose more fragile. This type of wear, usually invisible, affects the performance of your regulator. At the worst, your hose will end up by breaking, usually at the point where it is crimped.
Regularly check your hoses and replace them if cracked.
Replace your hoses at least every 5 years.
SUBEA-TRIBORD advises you to service your regulator every two years and to make a visual inspection at least once a year. This two inspections must be made in a SUBEA-TRIBORD certified workshop.
A service is also recommended after a particularly intensive season (more than 100 dives), or after a long period of inactivity.
During this inspection, your hoses will be checked and replaced if necessary.
Never use solvents or hydrocarbon-based products to clean or lubricate the regulator yourself.Never use spray cans, because the gas propellent can attack the plastic.
Use a silicone grease to lubricate the seals and increase their lifespan.
0.143 kg


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Anchors Steeped In Catholic Tradition to Provide Expert Daily
Commentary, Behind the Scenes Features, and Exclusive Interviews
UNIONDALE, N.Y.–(BUSINESS WIRE)–Tune in starting at 3:30PM ET on September 22, 2015 for the start of six
(6) days of in-depth coverage of the Pope's Apostolic Journey to
America. While many networks will cover this historic event, only
Telecare TV will provide non-stop reporting and exclusive coverage from
the Catholic perspective.
You can watch Telecare TV's coverage here:
live and on-demand
- Telecare App (available at the App Store)
Cable TV: Optimum channel 29/137, Time Warner Cable channel 471,
Verizon FiOS channel 296
Telecare TV is pleased to offer a free embed link if you would like to
feature their coverage of this historic event on your own website. Go
here: http://tinyurl.com/pba2afx.
Msgr. Jim Vlaun will be joined at the anchor desk by Bishop William
Murphy, Bishop of the Diocese of Rockville Centre, Emmy Award winning
journalist, Jane Hanson, co-host of Everyday Faith Live, Sister Mary
Alice Piil, along with Msgr. James McNamara, Father Nicholas Lombardi
S.J., and Father James Maher, President of Niagara University, in
addition to a team of correspondents at each event.
For a complete schedule of events please visit: http://www.TelecareTV.org.
About Telecare Television
TV – The Best in Catholic Television! ® is a not-for-profit,
state-of-the-art television and production facility. For more than 40
years, Telecare Television has been dedicated to answering a critical
need: to provide millions of viewers with quality, value-oriented
Catholic television. Our broadcast schedule airs 7 days a week, 24 hours
a day, reaching millions of households.
Telecare Television
Joseph Perrone, 516-538-8704 x145


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Author Archives: whocaresreviews
Podcast Against Type Episode 3: Oscars Part 3 of 5
We have just passed the halfway mark with this episode of Podcast Against Type's Oscars observation. Today, I talk about the nominees for Best Visual Effects, Editing, Costume Design, Cinematography, and the highly competitive Best Actress categories. Which leading lady … Continue reading
Posted in Podcast Tagged academy awards, academy awards 2017, academyawards, academyawards2017, actress, allied, Arrival, best actress, cinematography, costume design, Deepwater Horizon, doctor strange, editing, elle, emma stone, film podcast, filmpodcast, florence foster jenkins, Hacksaw Ridge, hell or high water, Isabelle Huppert, jackie, kubo and the two strings, la la land, lion, loving, meryl streep, moonlight, Natalie Portman, oscars, oscars 2017, Podcast, Rogue One, Rogue One A Star Wars Story, ruth negga, silence, Star Wars, the jungle book, visual effects Leave a comment
Podcast Against Type Episode Two: Oscars part 2 of 5
Welcome back to the second episode of Podcast Against Type! In this Oscars episode, I look at the nominees for Best Sound Mixing and Editing, Best Original Score and Song, and the possible winner from the Best Actor category. Who … Continue reading
Posted in Uncategorized Tagged 13 Hours, 13 Hours the Secret Soldiers of Benghazi, academy awards, academy awards 2017, academyawards, andrew garfield, Arrival, captain fantastic, Casey Affleck, cinema, Deepwater Horizon, denzel washington, fences, film, film podcast, filmpodcast, films, Hacksaw Ridge, jackie, james foley, justin timberlake, la la land, lion, manchester by the sea, moana, movies, oscars, passengers, Podcast, Rogue One, Rogue One A Star Wars Story, ryan gosling, Star Wars, Sully, trolls, viggo mortensen Leave a comment
Podcast Against Type Episode One: The Oscars (Part I of 5)
After years of inactivity, I have returned to my child named WhoCaresReviews. I have great ideas ahead for myself, and my reopening of WCR is part of those plans. After stints on other platforms, I will begin to reuse this … Continue reading
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2013 BAFTAs
Before I start, I'd like to direct your attention to an excellent website that focuses on all forms of entertainment called Live in Limbo. It's run by a friend of mine, and it's well designed, well informed, and sleek … Continue reading
Gangster Squad
Rating: 2.8/10 Flashy? Definitely. Sexy? Unquestionably. Captivating? … Continue reading
Let's Rant: Zero Dark Thirty Controversy
In a new video segment I have started called "Let's Rant", kind of like a Let's Play but not even remotely, I will discuss current controversies and issues with films/movies. This isn't to rant about bad movies. This is to … Continue reading
Posted in Rant Tagged academy awards, argo, Ben Affleck, boycott, boycotting, controversy, jessica chastain, kathryn bigelow, mark boal, oscars, snubbing, torture, zero dark thirty Leave a comment
Les Misérables
Rating: 7.3/10 Oh what an emotional … Continue reading
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Dr Love is a five reel, 20 payline from NextGen and the sequel to the phenomenally popular Dr Love.
Ever the opportunist, Dr Love has felt he's been overdoing it a bit at the office. We can't really go into the details as to the how's, why's and, ultimately, who's, but suffice to say he's left feeling exhausted so he's decided to take a break.
With incredible bright and colourful graphics, cheery sound effects and jazzy music, Dr Love On Vacation is an attractive slot with plenty of exciting gameplay. Symbols include get well wreaths, the doctor's suitcase, his stethoscope, a jumbo jet, a beach ball, Martinis, deckchairs, a former patient now pink from sunburn, and the lovely nurse in her skimpy bikini.
As in the previous game Dr Love is wild as wild can be. The surfboard is the scatter and can bestow free spins from 12 right up to 20 with a huge 6x multiplier – oooooooh!


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Mining Project Rehabilitation and Closure Guidelines: Papua New Guinea
Mine closure and reclamation should be conducted progressively and planned for from the early stages of a mining project in order to maximize the beneficial outcomes following closure.
Opportunities to achieve sustainable post-mining land uses decrease over time. Poor decisions in planning and operation made early in the mine life can reduce closure options and result in poorer closure outcomes related to land stability and fertility, water quality, biodiversity and aesthetics.
Papua New Guinea (PNG) is home to mining operations that range in scale and proximity to communities. Mining operations last from a few years to decades, and vary in their degree of rehabilitation and mine closure (RMC) planning. This document is intended to provide direction on RMC planning in PNG, including through RMC Plan evolution throughout the mine life, plan contents and submission requirements, financial assurance (FA) provisions and inclusions/exclusions. Guidance on sustainable post-closure land use, closure criteria and community engagement is also provided.
This document provides guidance for the administration, regulation and monitoring of the rehabilitation and mine closure obligations in PNG, with the understanding that mine sites exist in various stages of operation and evolution (through proposal variations and permitted amendments) and will consequently require different content within their RMC Plans. The spirit and intent of this document is in conformance with the Asia-Pacific Economic Cooperation Mine Closure: Checklist for Governments and the International Council on Mining and Metals Integrated Mine Closure – Good Practice Guide (2nd edition), both of which may be reviewed for additional background information.


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Undergraduate CDU-IND11-2020
Indonesian Studies 1A
Start down the path to speaking and writing in the Indonesian language.Steep yourself in Indonesian culture. Learn to ask for directions and talk about your family. Grapple with the essentials of Indonesian's rules of grammar and sentence structure.
Enrolments for this year have closed. Keep exploring subjects.
Study method
Online and other materials
Available loans
100% online
Prior study
Not required
Subject details
The aim of the subject is to provide students with the first steps towards a sound, practical command of basic Indonesian.
At the completion of this subject students will be able to:
- demonstrate and apply a basic understanding of the grammatical system of Indonesian language
- read and respond to simple authentic Indonesian language sources
- demonstrate an understanding of many fundamental aspects of Indonesian cultures and compare these to Australian thinking and practices
- write basic compositions in Indonesian
- participate competently in everyday social conversation in Indonesian within the range of topics covered
- participate competently in pair and group interaction in Indonesian.
- Self and family
- Time and daily activity
- Buy and sell goods
- Directions and locations
- Describing people and places
Study resources
Instructional methods
- Audio/Video conferencing
Online materials
- Resources and Links
- Printable format materials
- Online Assessment
Other materials
No eligibility requirements
Special requirements
No special requirements
Curious about Indonesia and would like to get to know the country and its people in more depth? This subject provides an introduction to the Indonesian language for students with little or no prior knowledge of the language. It is designed to guide the student to a basic level of proficiency, to be built gradually from beginning to more advanced levels. Spoken language, basic grammar and the general structure of discourse are introduced systematically to enable students to gain a good working knowledge of the language.
- Writing Language Exercises (14%)
- Oral presentation (20%)
- Role Plays (2) (28%)
- Essay - Indonesian (500 words) (30%)
- Oral language exercises (8%)