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Get the latest NHS information and advice about coronavirus (COVID-19).
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Check if you or your child has coronavirus symptoms
Find out about the main symptoms of coronavirus and what to do if you have them.
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Get a test to check if you have coronavirus, understand your test result and find out what to do if you're contacted by NHS Test and Trace.
Self-isolation and treatment if you have coronavirus symptoms
Advice about staying at home (self-isolation) and treatment for you and anyone you live with.
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Advice for people at higher risk from coronavirus, including older people, people with health conditions and pregnant women.
Social distancing and changes to everyday life
Advice about avoiding close contact with other people (social distancing), looking after your wellbeing and using the NHS and other services.
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'Your COVID Recovery' helps you to understand what has happened and what you might expect as part of your recovery.
GOV.UK: coronavirus – guidance and support
Government information and advice.
GOV.UK: local restrictions – areas with an outbreak of coronavirus
Local outbreak advice.
Priory Gate Practice1st Floor City of Coventry Health Centre2 Stoney Stanton RoadCoventry, CV1 4FSTel: 024 76 961 370
Priory Gate will be closed from 12:30 on Wednesday to allow Doctors to attend "Protected Learning Time" teaching. Our phones will be automatically diverted to Care UK call handlers.
We will reopen at 8am on Thursday 24th
Priory Gate will be closed from 12:30 on Wednesday to allow the Doctors to attend 'Protected Learning Time' teaching. Our phones will be automatically diverted to Care UK call handlers.
We will reopen at 8am on Thursday 13th February
We have received our stocks of flu vaccines for the current Season. If you have not heard from us and wish to be vaccinated please contact the Surgery.
Priory Gate as a reseach practice are keen to assist patients with the use of long term opioid medication that is taken for pain managment. Patients are encouraged to consider an on-line study in conjunction with Keele University. Full details can be found at WWW.promppt.co.uk
Priory Gate Practice is now a Registered Parkrun Practice and we plan to be running at 9am in the Memorial Park in Coventry. If you are interested. If you wish to join us follow the link below and register. We will post on here when staff are running
We are in the process of introducing a text message reminder service at Priory Gate so please ensure you provide us with an updated mobile number when you have contact with us and let us know as soon as possible after you have changed your number.
If you prefer for us not to have any contact this way please let the reception team know.
Priory Gate is looking to expand our Patient Participation Group. The Group meet quarterly and support the Practice with a range of activities. If you are a patient and would like to consider joining the group please contact the Practice Manager Glenn Walker to express your interest or to have an informal discussion. email@example.com or 02476 961370.
Priory Gate Practice is honoured to have received 5 shortlisted nominations for the first GP Alliance Awards event that took place on Friday 6th July.
The following are the shortlisted nominations:
GP of the year 2018 - Dr Helen Tyrrell
Practice of the year 2018
Practice Nurse of the year 2018 - Dawn Barker
Unsung Hero of the year 2018 - Dionne Morgan
Practice Manager of the year 2018 - Glenn Walker
The Partners and staff were delighted to be shortlisted for 5 awards ( more than any other Practice of the 65 that make up the Alliance) and Dr Tyrrell was thrilled to receive her award.
Priory Gate Practice aims to be fully compliant with the new GDPR Regulations. As part of this we have prepared a Privacy Statement describing how we handle and deal with your medical information. A copy of this is available for you to download under the Further information GDPR tab on the right.
Please ensure you advise us of any change in your circumstances including contact numbers, email and address to enable us to maintain appropriate contact with you.
Priory Gate appoints new Partner
We are delighted to welcome Dr Claire Kelly who has recently joined Priory Gate from a surgery in Kenilworth. Dr Kelly is a trainer and will bring to the Practice 10 years of experience of working as a GP. Dr Kelly worked with us for 4 months before being appointed a Partner in January 2018.
The Coventry & Rugby CCG (the CCG) has recently authorised a mail drop to all Coventry households advising that the aim is to share the information on your GP record with other associated Health Care Professionals when needed. The aim of this project is to allow them to view this information as required as part of your care and treatment.
If you do not wish for your information to be shared please let either the Reception team or Clinical team know this when you are next in contact with us.
Priory Gate have formed an alliance with a number of Practices across the city and are now able to offer appointments between 6.30pm and 9.45pm between Monday to Friday and at daytime on Saturday and Sunday. These additional clinics are based nearby on Broad Street Surgery- just off Stoney Stanton Road and are manned by GPs working across the City. In addition two further sites in Coventry are also available for these extended appointments. If you wish to benefit from these appointments please contact our reception team before 6.30pm on Monday to Friday.
All patients now have the right to access some of their medical records on- line. Please speak to the Practice Manager Glenn Walker if you would like access to this facility.
All Patients of Priory Gate now have a named accountable GP. The named GP is largely a role of oversight, with the requirement being introduced to reassure patients they have one GP within the practice who is responsible for ensuring that this work is carried out on their behalf. Dr Beaumont and Dr Tyrrell undertake the bulk of this role, however please ask at Reception if you do not know who your named accountable GP is.
If you are unable to attend an appointment at Priory Gate please contact us at the earliest opportunity to enable the appointment to be made available to other patients. The cost to the NHS for one week of missed appointments is usually around £2000.
Priory Gate is authorised to provide Yellow Fever vaccinations. Our Prescribing Nurse Dawn Baker has undertaken appropriate training for this service. The cost of this service is £60 per patient and this includes a certificate with the vaccination. Duplicate certificates if they are needed can be provided for £10.
Survey report 2013/2014 ppg_report.doc_2012-2013.doc Patient Participation Report 2011/12 ppg_report.doc_2012-2013.doc
PPG Report
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United tells pilots no alcohol for 12 hours before flights
United Airlines is setting an earlier cut-off time for when pilots must stop drinking alcohol before flights.
The airline is telling pilots they must abstain from alcohol for 12 hours before flights, up from the previous eight hours.
The change in the rule — it's called "bottle-to-throttle" in the airline business — comes several days after two United pilots were arrested in Scotland and charged with suspicion of being under the influence before a flight to the U.S.
The old 8-hour limit complied with Federal Aviation Administration rules, which also prohibit pilots from flying with a blood-alcohol content at or above 0.04%. Almost all states make it a crime to drive a car at or above 0.08%.
An extra four hours will help social drinkers sober up, although it might not be long enough for a heavily drunken person. Some researchers calculate that once someone puts down the bottle, their blood-alcohol level drops 0.015% each hour. At that rate, a drinker could go from 0.12% to zero in eight hours, or from 0.18% to zero in 12 hours.
United sent a bulletin describing the new policy to pilots a week ago, and it took effect last Saturday.
"This policy is being changed to help assure pilot compliance with standards established by the United States and individual states where United operates around the world," the bulletin said. It warned that meeting the 12-hour ban doesn't guarantee that pilots will be in the clear — some countries have a zero-tolerance policy on blood-alcohol content.
The Air Line Pilots Association, which represents United's pilots, did not respond to phone and email requests for comment.
A United spokesman declined to say whether the change was due to the arrests of two United pilots on Aug. 3 in Glasgow, Scotland, before they were scheduled to operate a flight to Newark, New Jersey. The flight was canceled.
Spokeswomen for Southwest Airlines and Delta Air Lines said their airlines follow the FAA's current standard of no drinking within eight hours of duty. Neither indicated a change in the works. American, Alaska and JetBlue did not immediately describe their policies.
United's new policy was first reported by Skift, a travel industry media company.
The arrests of the United pilots followed other recent incidents. In May, an American Airlines pilot received a suspended six-month sentence after pleading guilty in a U.K. court to drinking before a Manchester to Philadelphia flight. In July, a Delta Air Lines pilot was arrested before a flight in Minneapolis — airport police said he had an alcoholic container in his possession.
Incidents involving alcohol and on-duty airline employees aren't limited to pilots. On Aug. 2, a flight attendant was arrested after a United Express flight landed in Indiana. Passengers said she slurred her words during the pre-flight safety demonstration, then passed out in her jump seat.

subset: commoncrawl


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Nob Hill Blogs
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"Explore Pride Tours 2012"
Gay owned and operated,Explore San Francisco is pleased to announce Pride Tours 2012. Want to see the city above and beyond the parade, festival and the clubs? We offer the GLBT community tours and sightseeing within our community but outside of the box. Food tours, walking tours, running tours, 1970s Folsom District walk, or even porn studio tours. We accomodate groups and we offer sightseeing with transport provided by van service, SUV or town car. You may find the perfect choice from our regular itinerary or let us create something special for you. Please call the Pride Desk at 415.793.1104 or email email@example.com
Scenic RunningSan Francisco is the perfect city for running, incomparable scenery, varied terrain and mild temperatures. Take one of our scheduled runs or let us lead you on a custom run.
North Beach & Chinatown at NightThis tour is very social, we have fun and friendships are made. Maybe its the wine or exotic teas, good food, the company or the vibrant area, but if youre looking for a great evening, you cant go wrong with this fun event.This is part of our regular line up, 4 or more and well have a GLBT outing.
Side StreetsSan Francisco, California is one of the most walkable cities in the country. We have walking tours all over the city. Choose from our regular line up of tours, or let us design something for you. 415.793.1104
Folsom DistrictRelive the 1970s Miracle Mile and The Folsom District in all of its glory. See just the Folsom or combine this with a tour of the SF Armory, home of Kink.com. Select tours go to Treasure Island MediaUpon Request
Anniversary or birthday celebration, Pride Party to never forget, personal milestone, marriage proposal, business proposal, romantic evening or just something new and different. Give us your vision and let us expertly and meticulously make your extraordinary event a lifetime memory. 415.793.1104
Shuttle, Van or Town CarANapa, The Russian River, Black Sand Beach, or San Gregorio are all popular GLBT destinations within driving distance. We have transportation for any size group. Please call the Pride Desk for these spots or anywhere else you might like to see! 415.793.110
via "Explore Pride Tours 2012".


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Brussels, 22 May 2012 – The European Commission launched a new viral clip today as part of the "Generation Awake!" campaign, which alerts consumers to the dangers of unsustainable patterns of consumption. The clip features Water Maniac Walter, a neurotic bucket who addresses the theme of excessive water use. The clip links to the Generation Awake website, a multilingual site intended to get citizens thinking about their consumption habits, and help them change their behaviour so as to live more sustainably.
A number of other activities will also be launched this year as part of the campaign, including a new section on the website looking at the water footprint of goods such as jeans, hamburgers or beer. A video competition open to the general public will be launched in September 2012, and live events will be organised to inspire people and drive behaviour change in Italy, the Netherlands, Romania and Spain, in early autumn.
Generation Awake is the European Commission's campaign on resource efficiency. The aim is to raise awareness about the environmental, economic, social and personal consequences of using resources unsustainably, and to trigger changes in consumption patterns and behaviour. Ultimately, the goal is to help citizens develop a responsible consumption reflex as a matter of routine.
Since its launch in October 2011, the campaign website, which is available in 23 EU languages, has generated over 200 000 page visits. The campaign video has been viewed by over 1 million people and the Facebook page () has attracted close to 13 000 fans. The campaign has been specifically designed to address young urbans and families across the European Union, not only to build awareness about the importance of resource efficiency but also to encourage them to change their habits.
For more information:
Full details on the campaign's multilingual website: www.generationawake.eu
The Campaign's Facebook page: www.facebook.com/generationawake
Source: EU Press Service
The Brussels based United Nations Regional Information Centre for Western Europe - UNRIC provides information on UN activities to the countries of the region. It also provides liaison with institutions of the European Union in the field of information. Its outreach activities extend to all segments of society and joint campaigns, projects and events are organized with partners including the EU, governments, the media, NGOs, schools and local authorities.
United Nations Regional Information Centre for Western Europe (UNRIC Brussels)
Residence Palace, Rue de la Loi/Wetstraat 155, Block C2,7th and 8th floor, Brussels 1040, Belgium
Tel.: +32 2 788 8484 / Fax: 32 2 788 8485


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This is the last in a four-part special report on special needs planning for advisors and their clients. In part four below, a look at how advisors prepare to give this specialized advice .
Scott MacDonald, a Modesto, Calif.-based Merrill Lynch advisor who helped to develop this latest iteration of the special needs calculator, calls it a "user-friendly starting point" for families to look at planning for a loved one's needs in conjunction with their own retirement needs, and how much they need to save or insure for.
He cites his own brother's family as an example. "I have an autistic nephew," he says, "very low-functioning, but he will be fine till [his] mom and dad are gone. Then he will need care giving and a group home, and how will they pay for that?" Such substantial expenses can be accommodated if properly planned for, but too often families don't get that far in the process.
MacDonald (left) adds that there is also the necessity to plan for other, nonfinancial issues, such as writing a letter of intent to specify how the boy's parents want their son taken care of—something that will specify for caregivers his "wants, loves, hates, and needs."
Merrill's specialized advisors who carry the Certified Special Needs Advisor designation have been trained to help with that, and also to consult with outside experts such as specialized attorneys and health care providers.
While Merrill stresses that its CSNA designation and "Special Needs Financial Services Program" are unique in the industry, MassMutual also offers a special designation catering to families with special needs–available at present only to MassMutual agents, and offered through The American College–called the Chartered Special Needs Consultant , and its own program to assist such families, called SpecialCare.
As reported last year in Investment Advisor magazine, that designation/program combination also delves into the more arcane aspects of special needs planning, which includes everything from the proper use of insurance for a special needs family to the particular aspects of estate planning and tax law that can make or break a plan for the long-term care of a special needs individual.
There is also, as previously reported by AdvisorOne.com, the practice of advisor Mary Anne Ehlert, Protected Tomorrows, which offers webinars and partnering for financial advisors on the unique aspects of planning for special needs families.
It takes approximately 18 months to qualify for Merrill Lynch's CSNA designation, says MacDonald. According to Chris Sullivan (left), head of Special Needs Financial Services for Merrill Lynch, there are three core areas of training and coursework.
Part one, says Sullivan, "tackles the scope of the disability and special needs community and how no family is like another … advisors are also educated on the solutions, tools and resources available to them and their clients through the firm's 'Families of Children With Disabilities and Special Needs Planning Program,' as well as training on a team-based approach to ensuring a family or individual's financial, legal, social and medical needs are met."
Part two, the "Legal and Personal Aspects of Special Needs Planning" phase, offers online coursework in estate planning for families with children with disabilities, the use of letters of intent and special needs trusts.
Part three offers additional education through phone-based sessions with outside professionals in the legal and special needs community, says Sullivan, as well as discussion of specific cases highlighting the uses of special needs trusts, estate planning, care management, work with disability organizations, pooled trusts, and insurance when working with families and other caregivers.
Advisors who earn the designation, says Sullivan, can remain engaged with the program via ongoing emails with additional information to broaden their knowledge of the field.


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Tax Return Tithing
To those of you well-situated enough that you actually pay taxes, congratulations! Good job working hard for your money, and sorry about what's going to happen to you in April.
To those of us, however, who fall into the tax bracket known as "pitiful slobs," this is the most wonderful time of year. It's the time of year when daddies are allowed to buy socks that don't have holes in them, and frugal moms splurge on extravagant items like car registrations and non-irregular ketchup. Yes yes, it's tax return time!
Can o' worms disclaimers:
1. Tithing is a fabulous and praiseworthy practice, and something to be striven for, but it is not possible for all families. Giving generously and significantly from what you have is required by the Church; giving ten percent is not. (See CCC #2043)
2. Taxes don't count as charity, even if some of your tax money does go toward supporting some of those icky poor people (yes, I have heard otherwise sane Catholics argue this line). Taxes are for Caesar, charitable donations are for God, and Catholics are supposed to pay both.
3. Why, yes, America is being ruined by irresponsible people like us who go on and have forty-seven children that we can't even afford to outfit in Brooks Brothers suits with a Rush Limbaugh logo embroidered on the lapel. We should pull ourselves up by our bootstraps, quit whining, and take the triple extra overtime shift in the coal mine so we will have something to leave to the Pat Buchanan Young Monsters Brigade in our will.
4. I'm still spending part of our tax return on beer, and you can't stop me. Or even make me feel bad about it.
Okay, with that out of the way: what we have decided is that, if we can't manage to tithe every month, we can at least tithe from windfalls—and the greatest of these is our annual tax refund.
We generally donate a medium amount to the local crisis pregnancy center, and a large amount to Save a Family Plan. This is our favorite charity because it has an extremely low overhead, with no monkey business, and it gets results. This is not heavy-handed, bureaucratic, temporary-shower-of-gold-style charity: it's intensely local and very personal. And it's run by nuns, so you're not going to end up accidentally funding some hideous sterilization program, as you might with UNICEF or United Way.
Here's how it works: in the Family Deveopment Program, your family helps a family in India with "immediate needs such as food, clothing, medicine or education"; and then the organization "encourages each family assisted to become self-reliant and productive within the context of their local economy." From the website:
purpose of assistance
Provide basic human needs (food, medicine, shelter)
Cover some of the educational costs of children so they can attend school
Offer skills development opportunities for parents
Enhance employability through training
Provide means for these families to own livestock to have an improved diet and to give them an asset
Assist families in financing entrepreneurial initiatives such as small retail stores called petty shops, bicycle repair centres, teashops, fishing businesses, etc.
how it helps poor families
Reduces their indebtedness
Improves their living conditions
Reduces the burden on single parents such as widows and widowers as well as abandoned women
Augments present income for an immediate improvement in their standard of living
Provides avenues for subsidies and bank loans that would not normally be available to the poor
Provides a built-in support system with their local Sangham
You commit to supporting the family for a certain number of years, and will receive a photo, and letters from the family if you wish (and you may write back, too). A $240 annual donation ($20 a month) will send a family on its way toward self-reliance within six years. Save a Family Plan has helped more than 50,000 to become self-sufficient!
Lent is coming! An excellent time of year to think about lightening that pesky load in your wallet. I heartily recommend Save a Family Plan, but there are other fine homes for your money, as well. So, what's your favorite charity, and why?


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Will They Really Fix the Offensive John Paul II Statue?
I've blogged before about the UGLY John Paul II statue outside Rome's main train terminal.
Now Catholic New Agency is reporting that an effort is underway to fix it:
"I made a design for the sculpture that wasn't executed well in the foundry," explained the creator of the artwork, Italian sculptor Oliviero Rainaldi.
"It is not that we have come up with a new statue," he told CNA on Jan. 10. "We're correcting those details that weren't executed well" so that "it will be more faithful to my original idea."
The redesign will involve replacing the head, modifying the Pope's cape and touching up the outer coating of paint, since the bronze has oxidized to a light shade of green. The statue will also be raised 15 inches on a new platform, and its lighting will be improved.
. . .
Rainaldi told CNA in a June 2011 interview that his avant garde design is intended to manifest the inner-life of Pope John Paul II, instead of presenting a life-like photographic image.
"The man within was more interesting to me than the man outside," he said, describing a man who was "lacerated" inside "not only by his infirmity but also by his mission," the sculptor said. Rainaldi added, "this man showed he was beautiful for others reasons beyond his appearance."
Color me skeptical, but it doesn't sound to me like Rainaldi "gets it."
If you want to make a John Paul II memorial homeless person shelter then make a homeless person shelter and slap a sign on it. Don't make something that positively invites an internet caption contest.
Speaking of which . . . how would you caption this monstrosity?


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February 13 2011
Amber Benson's book signing tour. "Serpent's Storm," the third installment of Amber's Calliope Reaper-Jones series, comes out next Tuesday. More...
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This site will work and look better in a browser that supports web standards, but it is accessible to any browser or Internet device.


text: So im thinking about purchasing my first "new" board and found a good deal for a Surftech "No Brand" Stylish Nugget (9'3"). I was wondering what people thought of the surftech tuflite technology and wheather this would be an acceptable board for and beginner looking to advance. I live in southern maine so the summers can be pretty harsh. Learded on a 7'6" fish and am looking for a longer board for those small summer days.


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Nairobi Now :: arts, culture and events
On Friday 4 April 2014 the Somali Red Crescent and the British Red Cross will launch their case study "Principles in Action in Somalia" at an event hosted by the Nairobi Forum of the Rift Valley Institute.
Date: April 4, 2014
Venue: Seminar Room | RVI Office – Laikipia Road, Kileleshwa
Time: 10 am – 12:30 pm
The study examines the importance of the Fundamental Principles of the International Movement of the Red Cross and Red Crescent, first agreed in 1965, in the current humanitarian environment in Somalia. The study analyses the operational relevance and challenges associated with applying these principles.
The panel will comprise Dr Ahmed Hassan, President of the Somali Red Crescent Society, and Jane Backhurst, from the Humanitarian Policy Department of the British Red Cross. The meeting will be chaired by Dr Abbas Gullet, Secretary General of the Kenya Red Cross Society and Vice President, International Federation…
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EUropean Pharmacogenetics of AntiCoagulant Therapy - Acenocoumarol (EU-PACT)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01119261
Recruitment Status : Completed
First Posted : May 7, 2010
Last Update Posted : June 18, 2013
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
The narrow therapeutic range and wide inter-patient variability in dose requirement make anticoagulation response to coumarin derivatives unpredictable. As a result, patients require frequent monitoring to avert adverse effects and maintain therapeutic efficacy. Polymorphisms in cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase complex 1 (VKORC1) jointly account for about 40% of the inter-individual variability in dose requirements. To date, several pharmacogenetic guided dosing algorithms for coumarin derivatives, predominately for warfarin, have been developed. However, the potential benefit of these dosing algorithms in terms of their safety and clinical utility has not been adequately investigated in randomised settings. Objective: To determine whether a dosing algorithm containing genetic information increases the time within therapeutic INR range during anticoagulation therapy with each of warfarin, acenocoumarol and phenprocoumon compared to a dosing regimen that does not contain this information. Secondary outcomes of the study include cost effectiveness, number of thromboembolic and bleeding events, time to reach stable dose and number of supratherapeutic INR peaks. Study design: This is a two-armed, single-blinded, randomised controlled trial. In one arm (intervention) patients commencing anticoagulation therapy with either warfarin, acenocoumarol or phenprocoumon will be dosed according to a drug-specific genotype-guided dosing algorithm, which is based on genetic information, clinical data and (in the monitoring phase) previous INR. For the other arm (control) patients will be dosed according to a non-genotype-guided dosing regimen which does not include genetic information. The follow-up period per patient is 3 months. Study population: Newly diagnosed patients of both genders and at least 18 years old who need anticoagulant treatment with either acenocoumarol, phenprocoumon or warfarin within the low intensity INR range will be included in the trial. Main study parameters/endpoints: The % time within therapeutic INR range in the first 3 months of anticoagulation therapy. Nature and extent of the burden and risks associated with participation, benefit and group relatedness: Six extra blood samples are taken from each participant at the start of the study. Patients also have to attend 8 scheduled visits within the 3 months study period and are asked to fill in questionnaires. The genotype-guided dosing algorithm is anticipated to improve the accuracy of coumarin dosing and thus improve the safety and efficacy of anticoagulation therapy.
|Condition or disease
|Venous Thromboembolism Atrial Fibrillation
|Other: Genotype-guided dosing algorithm Other: Non-genotype-guided dosing algorithm
|Phase 4
|Study Type :
|Interventional (Clinical Trial)
|Estimated Enrollment :
|970 participants
|Intervention Model:
|Parallel Assignment
|Single (Participant)
|Official Title:
|EUropean Pharmacogenetics of AntiCoagulant Therapy - Acenocoumarol
|Study Start Date :
|November 2010
|Actual Primary Completion Date :
|June 2013
|Actual Study Completion Date :
|June 2013
|Active Comparator: Non-genotype-guided dosing algorithm
Other: Non-genotype-guided dosing algorithm
Loading and monitoring dose according to non-genotype-guided dosing algorithm
|Experimental: Genotype-guided dosing algorithm
Other: Genotype-guided dosing algorithm
Loading and monitoring dose according to genotype-guided dosing algorithm
- Percent time within therapeutic INR range 2-3 during 12 weeks following the initiation of coumarin therapy [ Time Frame: 12 weeks ]
- Time to INR > or = 4.0, which indicates overanticoagulation. [ Time Frame: 12 weeks ]
- Percent time spent > or = INR 4.0 [ Time Frame: 12 weeks ]
- Percent time spent < or = INR 2, which indicates under-anticoagulation [ Time Frame: 12 weeks ]
- Time to reach therapeutic INR defined as the time to the first INR within target range, providing that a subsequent INR > or =1 week later is also within target range [ Time Frame: 12 weeks ]
- Time to reach stable dose defined as INR within target range for a period of at least 3 weeks with <10% change in dose [ Time Frame: 12 weeks ]
- Time to and number of minor and major bleeding events [ Time Frame: 12 weeks ]
- Time to and number of thromboembolic events (therapeutic failure) [ Time Frame: 12 weeks ]
- The incidence of coumarin sensitivity [ Time Frame: 12 weeks ]
- The incidence of coumarin resistance [ Time Frame: 12 weeks ]
- Number of coumarin dose adjustments [ Time Frame: 12 weeks ]
- The clinical utility of the rapid genotyping test developed by LGC [ Time Frame: 2 years ]
- Quality of life as reported by the patient tested by the EuroQol (EQ)-5D questionnaire [ Time Frame: 12 weeks ]
- The cost-effectiveness of genotype-guided dosing for each coumarin compared with non-genotype-guided dosing [ Time Frame: 2 years ]
- Number of patients with INR > or = 4.0, which indicates overanticoagulation [ Time Frame: 12 weeks ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients with either venous thromboembolism (VTE) or atrial fibrillation (AF) requiring coumarin therapy for at least 12 weeks and a target INR in the low intensity range (INR range 2-3 in the United Kingdom, Sweden, Germany, Austria and Greece and INR 2.5-3.5 in the Netherlands)
- Age ≥ 18 years
- Ability to attend scheduled visits
- Signed informed consent
Exclusion Criteria:
- Presence of a mechanical heart valve
- Severe cognitive impairment
- Known genotype CYP2C9 or VKORC1 at start of the study
- Previous or current treatment with any coumarin
- Pregnancy or lactation
- Non-eligible subject
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01119261
|Democritus University of Thrace Medical School
|Alexandropoulis, Greece
|Utrecht University
|Utrecht, Netherlands
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Anke-Hilse Maitland-van der Zee, PharmD, PhD, Utrecht Institute for Pharmaceutical Sciences
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
223062 ( Other Grant/Funding Number: European Union - Seventh Framework Programme )
2009-016992-31 ( EudraCT Number )
|First Posted:
|May 7, 2010 Key Record Dates
|Last Update Posted:
|June 18, 2013
|Last Verified:
|June 2013
Venous thromboembolism (VTE)
Atrial fibrillation (AF)
Atrial Fibrillation
Venous Thromboembolism
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes
Embolism and Thrombosis
Vascular Diseases


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Tell me on a Sunday is a series of storytelling events held at the Ikon Gallery, where selected tellers go up on stage and tell their anecdotes relating to a set theme. Before the event commenced there was a chance to socialise with other audience members, in the gallery's cafe that serves tea, coffee and soft drinks and even muffins.This week's Tell Me on a Sunday was based around the theme of 'Strange Encounters'.
The dim-lit, small and social audience make the sharing of stories an intimate event. It is hosted by Cat Weatherill, one of Europe's leading performance storytellers who set the theme after being inspired by Valentine's Day. She responded well to each seven-minute performance, drawing us in and out of each teller's life. Some of the storytellers told their story in a very conversational way, using hand movements to express themselves, which further added to their performance. The comedienne Naomi Paul, however, crafted her story with a performance perfect structure instead of a conversational anecdote. Her story provided a neat beginning, middle and end.
The stories range from humorous to tragic and 'all with truth at their heart'. This just goes to show how far the theme can be interpreted. One story, by a retired teacher-turned-writer touched us all as he told us how his failed attempt at resuscitating a person has had a lasting effect on his life. Furthermore, the idea of not knowing the young man's name still stays with him today.
Journalist William Gallagher enticed us to his story with his love of Sci-fi; he made us believe that he had actually witnessed, in his own words, a 'shiny glowing disc'. Not only a shiny glowing disc, but that a woman was abducted by aliens. This ended with the humorous realisation that the woman possessed the car keys.
Through the variety of funny and emotional stories, we were able to relate to some aspect of the tellers' experience. What I really loved about the event is that it goes back to the oral tradition of storytelling, where the teller is not restricted by the barrier of pen and paper, allowing the teller's story to flow and touch us in an authentic way.
By Malia Choudhury
The next Tell Me On A Sunday is at the Ikon Gallery Cafe on Sunday 17th March. To reserve call the Ikon Gallery (0121 248 0708). The facebook event is: https://www.facebook.com/events/150196501798295/.


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Known Issues[edit | edit source]
Question #1: Is the collection Czech Republic, Třeboň, Nobility Seignorial records, 1619-1859, Třeboň, V. 144 (1672) correctly named? Shouldn't it be 1679 not 1672?
Answer #1: The correct year is 1679.
Question #2: Sometimes when I search for a record, the images are not there, or the message says "Image Not Available." How do I find these records?
Answer #2: Whenever possible, FamilySearch makes images available for all users. However, ultimate rights to view images on our website are granted by the record custodians. Data Privacy rules prohibit viewing the following records: All birth images must be 100 years or older; all marriage images must be 75 years or older, and all death images must be 75 years or older.
If any record on a digital folder contains birth records from the last 100 years, for example, the entire digital folder is restricted.
The Historical Records collections will be updated each year to show new unrestricted records. FamilySearch respects and strives to adhere to all privacy laws respective to preserving and providing access to genealogical records in its collection.
If you encounter additional problems with this collection, feel free to report them at firstname.lastname@example.com. Please include the following information:
- If searching a specific collection: please include the name of the collection; include all search criteria used, including name, event, dates and places.
- If browsing this collection: please include the full path you followed to where the problem occurred. The browse path is located above the Image viewer window.
For example: Czech Republic, Třeboň, Nobility Seignorial records, 1579-1859 > Třeboň > V. 144 (1672) > Image 1 of 31
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Return to the Czech Republic, Archive of Třeboň, Nobility Seignorial Records - FamilySearch Historical Records article.
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Six go through as Atlético run ends
Thursday 8 November 2012
Article summary
Club Atlético de Madrid's winning run finally ended while six clubs qualified for the knockout rounds and Edinson Cavani scored four for a resurgent SSC Napoli on matchday four.
Article top media content
Article body
After winning 16 consecutive games in UEFA competition, Club Atlético de Madrid finally lost on matchday four as A. Académica de Coimbra pulled off a famous win, while Edinson Cavani produced the individual performance of the night and Taison perhaps the goal of the season.
Wilson Eduardo scored twice as Académica stunned the UEFA Europa League holders in Coimbra. Atlético still lead the way in Group B, but their loss allowed FC Viktoria Plzeň to pull level on points thanks to an emphatic 4-0 victory against Hapoel Tel-Aviv FC.
In Group F, another perfect record was ended as SSC Napoli came from 2-1 down to defeat FC Dnipro Dnipropetrovsk 4-2, the irrepressible Cavani scoring all four goals for the home side. In the same section, AIK's 1-0 triumph against PSV Eindhoven leaves the Dutch team struggling to make the knockout stages. PSV sit bottom, five points behind leaders Dnipro with two games to play.
FC Anji Makhachkala turned the tables on a youthful Liverpool FC to beat the English club 1-0 while BSC Young Boys chalked up a second win against Udinese Calcio. Just three points separate all the sides in Group A.
It is a clearer picture in a number of other pools with FC Internazionale Milano and FC Rubin Kazan through in Group H, while FC Metalist Kharkiv and Bayer 04 Leverkusen have achieved the same in Group K. Metalist overcame Rosenborg BK 3-1, the highlight of the encounter an incredible volley from Taison.
Other teams to advance include the only side to sport four wins from four, Olympique Lyonnais, who edged a see-saw contest at Athletic Club 3-2. Hannover 96 are also in the hat for the draw on 20 December after winning their own five-goal thriller against Helsingborgs IF.
Fenerbahçe SK and FC Steaua Bucureşti are on the verge of joining the qualified clubs while victories for Tottenham Hotspur FC and S.S. Lazio strengthened their respective positions in Group J


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There were times when Collin Klein's mother couldn't help but worry, when she would watch her son take a snap from center, dodge a couple of defenders and then take off at a gallop.
The play would usually end up with Kansas State's quarterback taking a big hit, the kind that caused Kelly Klein to gasp. The kid would invariably drag himself off the turf, blood usually seeping from his elbows. He would adjust his facemask, hike back his shoulder pads and trundle back to the huddle and do it all again.
``I get emotional because I do worry,'' Kelly Klein admitted this week. ``But he does what he loves to do, so you have to be grateful that he has the physical ability to do it.''
Klein's prodigious physical ability, along with his even demeanor, unwavering faith and singular focus on getting better bit by bit all contributed to one of the finest careers in Kansas State history. On Wednesday, he was voted the AP Big 12 offensive player of the year.
``I'm just honored with this opportunity that the Lord has provided me here at K-State,'' said Klein, who made the All-Big 12 first team as a quarterback and was honorable mention as an all-purpose player. ``I'm just happy to represent Kansas State, our team and what we've been able to accomplish this season.''
The Heisman Trophy finalist set a slew of records while helping the seventh-ranked Wildcats to an 11-win season, the third conference title in school history and a berth opposite Oregon in the Fiesta Bowl.
Klein is the first player from Kansas State to be voted the Big 12's top offensive player. He received 14 of the 18 votes from members of the media who regularly cover the Big 12, while West Virginia's Tavon Austin got three votes and Terrance Williams of Baylor received the other one.
``It's an amazing thing and it's a huge honor, but the reward, you know, is just seeing him do his thing, and do what he loves to do,'' said Klein's father, Doug Klein. ``Truly, whether it's recognized or not, that's the reward.''
Klein's coach, Bill Snyder, was voted Big 12 coach of the year for the third time on Tuesday.
``He deserves all the compliments he can have,'' Snyder said. ``He's awfully good at what he does, and he's awfully good as a leader and he's awfully good as a field manager, and he's awfully good in all the physical aspects of the game - and he's a tremendous person.''
Defensive end Devonte Fields of Big 12 newcomer TCU was voted AP's defensive player of the year. He received seven votes to beat out Kansas State's Arthur Brown (four), Horned Frogs teammate Jason Verrett (three), Iowa State's A.J. Klein (two), and Aaron Colvin and Tony Jefferson of Oklahoma (one each).
Fields was also the runaway winner of defensive newcomer of the year, while Baylor running back Lache Seastrunk was voted the conference's top newcomer on offense.
Klein has already won the Johnny Unitas Golden Arm Award, and is up for several other national awards this week. He's one of three finalists for the Heisman, along with Texas A&M quarterback Johnny Manziel and Notre Dame linebacker Manti Te'o, which will be handed out Saturday night in New York.
The senior from Loveland, Colo., was recruited to Kansas State under former coach Ron Prince, played for a while at wide receiver, and then transitioned back to quarterback. But he never approached the position in the way most do: He was just as comfortable bulldozing for yards as he was airing it out.
Klein threw for 2,490 yards and 15 touchdowns this season while running for 890 yards and 22 more touchdowns. He's the first player in the BCS era to have consecutive seasons with at least 10 touchdown passes and 20 touchdown runs, and the other three to even accomplish the feat once all won the Heisman: Auburn's Cam Newton in 2010, Florida's Tim Tebow in 2007 and Eric Crouch of Nebraska in 2000.
``Some crazy things have happened to lead our team and myself to this point,'' Klein said. ``There are a lot of reasons for that. There's a lot of hard work, a lot of preparation that have been put in on so many people's part, and so many people have invested in me when I was going through a hard time or struggling.''
Kansas State led the league with six first-team All-Big 12 selections: Klein, Brown, offensive lineman B.J. Finney, tight end Travis Tannahill, defensive lineman Meshak Williams and defensive back Ty Zimmerman. The Wildcats also had five second-team selections and eight honorable mentions.
Oklahoma State had the second-most first-team selections with five: running back Joseph Randle, wide receiver Josh Stewart, offensive lineman Lane Taylor and Quinn Sharp, who made it as both a punter and kicker.
Fields was joined on the first team by Verrett and TCU teammate Kenny Cain.
Oklahoma's Jefferson and Colvin were joined by Gabe Ikard on the first team. Baylor's Williams and Cyril Richardson, Texas Tech's LaAdrian Waddle and Kerry Hyder, West Virginia's Austin and Stedman Bailey, Iowa State linebackers Klein and Jake Knott and Texas' Alex Okafor also made the first team.


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For more than seven years, Dr. Robert Wood and a team of researchers from Harvard University have been studying flies and attempting to build a life-size, flying robot that can mimic the flight of living flies. The government is hopeful that robotic flies might one day be used as spies in surveillance missions, as well as to detect toxic chemicals used by terrorists. On July 19, 2007, MIT's Technology Review announced that Wood's "robotic fly has taken flight at Harvard University" (Ross, 2007). Dr. Ron Fearing of the University of California, Berkeley has been studying the dynamics of insect flight for years. In fact, he is Wood's former Ph.D. advisor. He called Wood's robotic flying insect "a major breakthrough" (as quoted in Ross).
What do brilliant scientists have to show for their seven plus years of research on flies? What was the "major project milestone" reported in Technology Review? Why was Wood joyfully "jumping up and down in the lab" (Ross)? Answer: his life-size robotic fly took off. It cannot maneuver in the air. It is unable to be controlled. It cannot avoid obstacles. It cannot slow down and land on a specific target. It does not have its own power source (and even if it did, it could provide no more than five minutes of power to fly). "At the moment, Wood's fly is limited by a tether that keeps it moving in a straight, upward direction" (Ross). Yet, since "a lot of people thought it would never be able to take off," such a feat is considered remarkable.
Admittedly, Woods and his colleagues have done a superb job in building a life-size robotic fly that can move upward on a tether by flapping its synthetic wings. It takes extremely intelligent individuals to develop their own fabrication process and manufacture a tiny robot that resembles and mimics (to some degree) living flies. Yet, these same men advocate that real flies, which have "long puzzled scientists and bedazzled engineers" with their "magical," "sophisticated," "intricate maneuvers," are the end result of mindless time and chance, i.e., evolution (Dye, 2007). Such a proposition defies common sense!
Were Woods and his team of researchers to leave hundreds of tiny carbon-polymer pieces lying around in a lab for 100 years (or one billion years!), no reasonable person would conclude that, eventually, time and chance would assemble a robotic fly, much less one that maneuvers as well as a real fly. It has taken intelligent, hardworking scientists more than seven years just to make a robotic fly lift off the ground.
Who made the often imitated, but never duplicated living fly that can "change the direction of its flight by 90 degrees in about 50 thousandths of a second" (Dye)? Who designed the fruit fly's "spiffy neuron-circuitry" that allows it to rotate from north to west and then zip westward "in one-fifth the blink of a human eye" (Dye)? Who made the fly, its sesame-seed size brain, and its complicated flight dynamics that scientists have been unable to "figure out" fully even after several years of study? Did mere time and chance create the common fly, which Dr. Michael Dickinson of the California Institute of Technology said has "the fastest visual system" and "most powerful muscles on the planet" (as quoted in Dye)? Should we conclude, as did Dr. Wood, that "[n]ature makes the world's best fliers" (as quoted in Ross)? Certainly not! Only a superior Intelligence outside and above nature's time and chance logically explains the existence of intricate design. Indeed, God is the builder and maker of all things (Hebrews 3:4).
Dye, Lee (2007), "Scientists Study the Amazing Flight of Flies," ABC News, [On-line], URL: http://abcnews.go.com/Technology/story?id=97651&page=1.
Ross, Rachel (2007), "Robotic Insect Takes Off for the First Time," Technology Review, [On-line], URL: http://www.technologyreview.com/Infotech/19068/.


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Justin Timberlake and Scarlett Johansson put their separate hacking scandals behind them to enjoy a night out together in New York on Wednesday.
The old friends met up at hotspot 1Oak and appeared to be happy and carefree, despite the drama of the cellphone leak fuss that erupted earlier after naked snaps of what appears to be Johansson in a bathroom and bedroom appeared online.
The actress is reportedly working with FBI agents to find out who hacked into her cellphone and distributed the saucy images.
And Timberlake could also be part of a widespread investigation after candid photos of the singer were allegedly taken from the cellphone of his "Friends With Benefits" co-star Mila Kunis.
But neither he nor his "What Goes Around… Comes Around" video leading lady showed any signs of stress as they partied through the night.
A source tells Life & Style magazine, "He was all smiles with her. Scarlett and Justin left together with two of his friends around 5 a.m. and hopped into a black SUV. You can tell the two are great friends and had a blast together."


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Tracking The Four: Voices of…Posted by EJacoby on February 24th, 2012
Evan Jacoby is a regular contributor for RTC. You can find him @evanjacoby on Twitter. TT4 will cover four selected teams of interest – Syracuse, Indiana, Murray State, and UNLV – by tracking their ups, downs, and exciting developments throughout the course of the season.
The 'wildcard' version of TT4 is back, and this week we take a look at the voices of each team. Below you'll find key quotes throughout the season from players, coaches, and media members who cover each of our four squads. With just three games remaining (or less) for each team in the regular season, it's an appropriate time to take the pulse of the programs before they head into the home stretch:
Indiana Hoosiers
- "They've been punking us the past couple years and we realized that. This year we had to go toe-to-toe with them." Guard Victor Oladipo, 12/31 (after win over Ohio State)
- "Our mindset is next man up. We know that a lot of different people at different times can step up and make a play that helps us win games on either offense or defense. We have done a good job of being unselfish and worrying only about getting the win." Guard Jordan Hulls, 1/3
- "The bottom line is this team gritted it out again. They have won 14 games 14 different ways with a lot of room for improvement, and I'm excited about them." Coach Tom Crean, 1/5
- "We can't be satisfied with moral victories." Center Cody Zeller, 1/18
- "I think the most difficult thing to swallow from one game to another, though, is simply the consistency of this basketball team in recent weeks. You really just don't know what you're going to get from week to week, game to game, minute to minute. And that's what I find to be the big difference between the 15-1 start and the 2-5 record since then. It comes down to consistency. And it's across the board." Beat writer Terry Hutchens of the Indianapolis Star, 2/2
- "If you're going to get physical with [Zeller], he's going to respond. The only soft thing about Cody is that he's soft-spoken on the court, but other than that he's a tough, tough person." Coach Tom Crean, 2/9
Murray State Racers
- "Coach has a great personality and he cares about our team more than anything, and the same way he cares about us we care about him and we try to go out and play as hard as we can for him." Guard Isaiah Canaan, 12/15


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LETTERS: Obama critics ignore reality; Bible's guidelines are clear; Obama is ruining U.S.
One of your Sunday letter writers could use a fact-checker, two memory pills and another Prozac. He opines that the Obama administration is corrupt, because two functionaries hail from Chicago Yes, this administration is the most corrupt since, well, the last one.
Bush allies were convicted, for outing a CIA operative, election fraud and bribery. Justice lawyers were purged. Torture was excused. The FAA was asked to interfere in Texas politics.
Our writer wants the INS to rigorously check out immigrants, but complains when the IRS expects non-profits to prove they're following the law.
As to the nonsense about Black Panther voter activism, that group has been defunct for three decades. The group that manipulates elections here is the Texas Legislature. Thanks to gerrymandering, county voters get to choose which Montgomery County Republican shall represent them.
Clearly our scribe got the 50-percent-on-government-checks number the same place he conjured the Panthers from. If he means my Social Security, I'll take to the streets before anybody entrusts it to those Wall Street speculators which crashed the economy.
Thomas C. Watson, Bridge City
God didn't say Adam and Steve, He said Adam and Eve. Gay marriage is against God's holy word.
Lydia Jane Robertson, Port Arthur
We have and administration that instead of taking care of law and order, the economy and safety is overwhelming us with race, gay rights, abortion and social issues.
We have a president who bypasses Congress boldly and openly governs by executive orders. He is systematically gutting industry after industry to our economic ruin. While to make a point, allowing sequestration on so many petty levels, Obama dares to spend $100 million in taxpayer money to go to Africa, an expensive summer vacation! What do we get in return?
We have a Congress that does not read bills before voting! Then who are the actual people writing these bills?
We have courts filled with party affiliates, rather than scholars of the constitution, to uphold the law of the land. The federal government failed to enforce laws and let 11 million people come and stay here illegally. How irresponsible and wasteful they are. We have an attorney general openly and deliberately lying to Congress and the people. IRS and other federal officials openly taking Fifth Amendment, refusing to tell the truth and cover up administration abuses. Now the IRS is going to oversee our health care system?
Someone tell me what is the solution.
Jeya Bharathi, Beaumont


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Sanya Richards-Ross
Sanya Richards-Ross | 12/17/2013, 3:09 p.m.
4x Olympic Gold Medalist, Entrepreneur, Reality Show Star
What is the significance of Black History Month to you?
"Black History Month is by far my favorite month, not only because I'm born in February, but just because it really gives us an opportunity to reflect on where we've come from and it highlights so many of the heroes in the African American Community. It also gives us a chance to see where we are and where we are going and how much more we have to accomplish. For me, Black History Month has always been very special."
What was the most poignant moment in Black History month to you?
"I think of Brown vs the Board of Education when schools were no longer segregated. And for me that always sticks out, because my coach, Coach Clyde Hart, he was actually a part of the first school in Arkansas that became integrated and he always talked about that. Sometimes, I can't wrap my mind around that moment because we're so used to being integrated."
Growing up who were the African-American Icons you looked up to and why?
"My very first role model was Merlene Ottey. She was a Jamaican celebrity sensation, one of the best 100 meter runners in history. I remember thinking as a young kid, I wanted to be just like her. Not only because of her strength and power on the track but she was always so poised, so relatable and did so much in the community in Jamaica. Similarly, my American role model is Jackie Joyner-Kersee. I loved her grit, her determination, and also all of the stuff she has done for St Louis, which is her hometown. To know her personally is a great thrill."
The first American woman to do so in 28 years, and only the 2nd in history, Sanya Richards-Ross became Olympic Champion over 400m at the 2012 Games in London by overtaking the competition in the last 50 meters of the race. The London games also saw Sanya become tied as one of the most decorated female track and field Olympians of all time after anchoring the 4x400m relay team to gold for the 3rd consecutive time.
A banner year in her career, the 2012 season got off to a roaring start for Sanya Richards-Ross. Having set four world-leading times over 200 and 400 meters in her first three competitions of the season, electing to participate in indoor competition for the first time in several years, has proven beneficial for Richards-Ross. Being crowned 400m World Indoor Champion and helping her teammates win the Silver as the anchor in the 4x400m relay has been the icing on the cake on her journey to her ultimate gold of becoming Olympic Champion in her flagship event later this year. With this achievement under her belt, Sanya began the 2012 season with high hopes, ambitious goals, and great expectations for what she hoped would be the best year of her career yet.
Sanya dedicated the 2011 season to working her way back to form. Her best performance of the year came in at the Aviva Grand Prix in London, where she turned out an impressive time of 49.66 seconds over 400 meters. Encouraged by her performance, Sanya went on to defend her individual World title at 400 meters in Daegu, South Korea, but fell short. She went on to lead her teammates to gold in the 4×400 meter relay, becoming a World Champion once again.


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End of Zen: Kobe Bryant's extension complicates Phil Jackson's return as L.A. Lakers' coach
The Quick Hit: There are many theories on the Los Angeles Lakers' recent struggles.
Perhaps, they're bored having all but locked up first in the Western Conference standings. Perhaps, players are distracted by the trappings of Hollywood. Perhaps, they miss injured giant Andrew Bynum more than they care to acknowledge. Perhaps, Kobe Bryant's on-going contract negotiations and unknown future was unsettling. And perhaps, tension exists between Bryant and Pau Gasol over shots and touches.Read More


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Where did you get the screen from behind Admiral Ackbar? I need to give R-3PO something to do in my Hoth display. He can be updating the Rebel Alliance's facebook status and twitter feed."The empire is striking back at us on Hoth"
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What were your choices? *spoilers* ALL EPISODES
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Identical twins Bill and Tom Kaulitz were not even twelve years old when they formed their band in Magdeburg in 2001. Four years later Tokio Hotel had their first number one hit in Germany – with the song Durch den Monsun.
Germany is not the only country where Tokio Hotel are teen heartthrobs. The band's singles, albums and DVDs have won gold and platinum in more than ten countries, from Hungary to Portugal and from Argentina to Russia. Tokio Hotel have been especially successful in France, where learning German suddenly became much more fun. In 2009 their third album Humanoid was simultaneously released in German and English – and promptly shot into the USA charts as well.
Két hasznos billentyűkombináció a böngészőn belüli zoomoláshoz:
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További segítséget az alábbi ikonra kattintva kaphat:


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**IMPORTANT**There is a maximum purchase of 2 units per shadow SKU (per order) for all the new Stained Glass Collection. For example, you can purchase 2 of the shade "Spire", but not 3. This applies to bundle, single listings etc. Any purchased overage will be refunded and not fulfilled. Thank you for your understanding! STAINED GLASS COLLECTIONThe "Stained Glass Collection" was inspired by the beautiful art of stained glass and the vibrant tones used to create these masterpieces. This collection consists of 92 multichrome shadows and includes four different formula types: Jewelled Multichromes, Iridescent Multichromes, Glitter Multichromes and Pastel Multichromes. For application tips, scroll down. Our shadows are made with pure, high-grade cosmetic-approved pigments. We don't use fillers in our product, only what is needed to bind the products. DESCRIPTIONGlitter MultichromesThese are glitter eyeshadows, not plastic-based glitters, as such, they melt into the skin. Their shelf-life is the same as that of a regular shadow of ours, 24 months. These have varying levels of opacity in the base colour and varying sizes of glitter particles. They are safe to use on the eyes and some on the lips (see individual listings). Engrave - Has a semi-sheer brown base with large glitter particles that shift from lilac/pink-orange-gold. APPLICATIONThere is a bit of a learning curve to these shadows, but we promise the effect will be well worth it. Below are a series of application tips to help you use these gorgeous products. We recommend doing your eye makeup prior to the rest of your face, as there may be some fallout while applying. Glitter Multichromes These are glitter eyeshadows, not gel-based glitters, as such they perform similarly to a standard, shimmer shadow and apply relatively easy to the lid when patted on with a finger. For maximum longevity and intensity, apply over a set primer. Larger-particle glitters work even better over a tacky base (glitter glue). You can apply them with your finger or a shader brush sprayed with a setting spray. Apply the shadow by patting it onto the lid. Don't swipe. Because of the larger particle sizes in these shadows, you don't have to worry about the product sealing in the pan. But this also makes them more delicate; so do not dig your brush or finger into the product roughly. STORAGE & CARETo maximize the shelf life of your products, keep them stored in a dry, cool and sealed place, like an empty magnetic palette. **Please Note**While we try to capture photos of our products as true to life as possible, they may appear slightly different in person from photos due to variances in lighting.
~ 100% Vegan and Cruelty-Free
~ Good For: Face, Eyes, Lips and Body.
~ 100% Talc and Paraben-Free
~ 2.4cm x 2.1cm rectangular pan, 1.5g x1


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2 oz Privateer Collection | The Plank Ultra High Relief Silver Round
Buy this magnificent 2 oz ultra high relief silver round, the fifth release in the Privateer series at the lowest price through our online store.
The reverse features a shirtless mutineer who has provoked the wrath of the pirate Captain. This special form of execution was employed to set an example for all others on the ship to see.
The obverse of this round features a skull centred over a ship's wheel, with the wheel set over a tattered sail. Entwined with the wheel is a braided line. Encircling the top of the skull is the phrase, "No Prey, No Pay". This was a common pirate law meaning a crew received no wages but, rather, shared whatever loot was taken.
This magnificent 2 oz round features a theme not often covered by government mints, private mints - or any mints for that matter. Pirates! This ultra high relief round makes a perfect gift for ship lovers as well as being a great way to introduce people to investing in silver. This round will only be in production for a limited time.
Multiples of 10 will ship in an original mint tube.
|United States
|Silver Shield
|Brilliant uncirculated
|A skull centred in a ship's wheel with a tattered flag in the background and the words "No Prey No Pay 2 oz Fine Silver 999"
|Ultra high relief of a mutineer walking the plank on a pirate ship.


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Naperville, IL -- (SBWIRE) -- 06/10/2014 -- Reportstack, provider of premium market research reports announces the addition of Research Report on Condiment Industry in China, 2014-2018 market report to its offering
Condiments in the report include monosodium glutamate, essence of chicken, soy sauce, vinegar, tomato paste and compound condiments.
The market size of condiments exceeded CNY 200 billion in China in 2013. The annual growth rate remains above 15% in recent years.
Soy sauce is the most important condiment in China with the production volume of 7.58 million tons in 2013. There are hundreds of soy sauce manufacturers in China. Chinese soy sauce industry is in the phase of bipolar differentiation. Major enterprises, such as Haitian and Lee Kum Kee, occupy most of domestic market shares while other enterprises become regional brands or merge with large enterprises.
The production volume of vinegar products exhibits upward trend in China. After years of rapid development, fruit vinegar and healthy vinegar occupy certain market shares in China.
In China, monosodium glutamate industry is highly homogeneous. Manufacturers are faced with pollution treatment with various requirements for environment protection from local governments. Moreover, Chinese consumers gradually transfer from monosodium glutamate to chicken essence and chicken powder as health concern increases. Therefore, Chinese monosodium glutamate industry is faced with severe problems. The chicken essence industry is mostly seized by leading enterprises in China. Totole is very popular in East China and North China while Knorr seizes the market in South China. Enterprises in the industry have huge potential for growth due to the large market space for chicken essence products.
The market of paste and sauce products grows rapidly with uneven development in China. Most fastest-growing enterprises are located in South China and East China. Sauce products with large sales volumes are chili sauce, meat paste, tomato paste and bean paste.
Downstream of condiment industry includes catering industry, household consumption and food processing industry. As market competition becomes intense, some foreign-funded enterprises develop food solutions (professional solutions in catering industry) to update the marketing mode. Unlike the sales of traditional condiments, enterprises send out professional consultants to design menus and develop cuisines for restaurants. They instruct chefs in standardized condiments and skills to improve the efficiency. The sales of the products increase as the enterprises maintain close relations with the chefs and restaurants.
Reasons that foreign-funded enterprises focus on food solutions in China are as follows:
1. Food solutions are the strength of foreign-funded enterprises as the business is already fully developed overseas. With the rapid development of condiment market in China, it is difficult for foreign-funded enterprises to defeat famous domestic enterprises in fields of traditional Chinese condiments, such as soy sauce and vinegar, due to the strong regional features. Therefore, foreign-funded enterprises avoid direct competition with domestic enterprises through differentiation in catering industry.
2. Catering industry possesses large demand for condiments. Chain enterprises can rapidly increase the sales value through close cooperation with catering industry.
The demand for condiments keeps increasing as economy develops in China. Meanwhile, the product structure is constantly upgraded. The market concentration rate will exhibit upward trend as condiment industry integrates in China in the coming years. Enterprises will enjoy advantages in market competition with effective food solutions.
Readers can obtain the following information or more through this report:
-Government Policies of China Condiment Industry
-Development Status of Sub-industries of Condiments in China
-Sales Channels of Condiments in China
-Analysis of Major Enterprises and the Operation Status in China Condiment Market
-Competition in China Condiment Market
-Import and Export Status of Condiments in China
-Distribution of Foreign-funded Enterprises in China Condiment Market
-Development Trend of China Condiment Industry
The following enterprises and people are recommended to purchase this report:
-Manufacturers of Condiments
-Raw Material Suppliers of Condiments
-Catering Enterprises
-Food Manufacturers
-Investors/Research Institutes Concerned about China Condiment Industry
To view the table of contents for this market research report please visit
Roger Campbell
United States
Ph: 888-789-6604


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Girls Frayed Denim Shorts (Kids)
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Best practices on indigenous knowledge
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This publication provides a series of case studies to illustrate how indigenous knowledge (IK) can be used to create sustainable development. It aims to suggest, by example, guidelines for development planning, as the practices described may give policy makers and development practitioners a deeper insight into the ecological and cultural complexity of sustainable development. Includes basic definition of IK and related terms, and indexes by country and theme