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Chemo drug offers new hope for HIV patients
Treating HIV patients first with a chemotherapy drug improved their response to an experimental gene-modifying technique for controlling the virus, according to Sangamo BioSciences.
The company presented new data from a small early-stage trial of its treatment, SB-728-T, on Thursday at the Conference on Retroviruses and Opportunistic Infections in Boston.
Shares of Sangamo were up 17 percent at $22.92 in late trading on Nasdaq. Shares of the Richmond, California company have gained about 67 percent so far this year.
On Wednesday, the New England Journal of Medicine published data from an earlier trial showed that Sangamo's strategy of genetically modifying cells from people infected with HIV could become a way to control the virus that causes AIDS without using antiviral drugs.
"Sangamo's HIV 'suppression' is promising, but very early and far from a 'cure,'" RBC Capital Markets analyst Michael Yee said in a research note. "This is very early study for technology and safety validation."
The technique is designed to disrupt a gene, CCR5, used by the human immunodeficiency virus to infect T-cells, the white blood cells that fight viral infections. A patient's cells are removed and processed to alter the DNA that codes for the CCR5 receptor. The altered cells are multiplied and tested, then infused back into the patient.
The results presented on Thursday show that increasing doses of the chemotherapy drug Cytoxan, or cyclophosphamide, before infusion with SB-728-T led to an improvement in both growth of the genetically modified cells and an increase in total CD4 immune system cells, which otherwise would be a target for HIV, according to Sangamo.
Two of three patients treated with the highest Cytoxan dose have remained off of antiretroviral drugs for several weeks with detectable, but stable, levels of HIV in their blood, the company said. In all, nine patients received Cytoxan to augment their treatment.
Cytoxan, made by Bristol-Myers Squibb, is used to reduce the number of T-cells in the body, which then rapidly repopulate once the drug is discontinued. The aim is to allow SB-728-T to be infused as new T-cells are growing in the body. Cytoxan is generally used to enhance effectiveness of bone marrow transplants in cancer patients and as therapy for autoimmune diseases.
The gene editing technique behind SB-728-T seeks to mimic the resistance to HIV observed in the small number of people who have inherited CCR5 mutations from both parents.
Sangamo has also been carrying out clinical studies in HIV patients who have one copy of the natural mutation.
So far, the company has used a deactivated virus to deliver its gene-modifying technology to patients but said it will shift to a new method using messenger RNA to deliver the cell-altering proteins. Messenger RNA is a single-strand molecule that carries information telling cells which proteins to make.
When a virus is used to deliver gene therapy, patients develop antibodies, making them immune to further treatments. By using messenger RNA, patients can be re-treated with SB-728-T if needed, said Sangamo spokeswoman Elizabeth Wolffe.
Sangamo said it has expanded the Cytoxan preconditioning study to determine the right dose of the chemotherapy. It then plans to treat an additional 12 subjects, using the new messenger RNA delivery method, this year.
"If those data are positive, plans are to move forward with pivotal trials with a pharma partner," said Sangamo Chief Executive Officer Edward Lanphier, referring to efforts to sign on a bigger drugmaker to help with funding. He did not give details on whom Sangamo might approach.
Sangamo is testing its "gene editing" strategy to develop therapies for a number of diseases, including inherited illnesses such as hemophilia, sickle cell disease and Huntington's disease.


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Twitter Fiction Festival breaks storytelling into bite-sized bits
"Twitter is a place to tell stories," wrote Twitter's Andrew Fitzgerald in a blog post announcing the event. "Often those stories are about news, or politics, or perhaps sports or music, but it turns out Twitter is a great place for telling fictional stories, too. As one professor from Michigan State University says, 'Tweeting can be thought of as a new literary practice.' We want to celebrate that."
A panel of festival organizers hand-picked a wide range of genres and concepts to feature. One participant will re-tell 100 Greek myths in 100 tweets. Another plans to invite Twitter users to help her write epigraphs for gravestones. Twitter also will showcase the serialized story of five strangers trapped on a bus, an exploration of censorship in China, and an interactive writing game that will involve the wider Twitter community.
"With this kind of medium, serialized writing can be taken in a totally new direction," said Johannes Neuer, associate director of marketing at the New York Public Library, which is hosting in-person facets of the festival. "All of the sudden you have readers in real time, and an opportunity to really incorporate the reader much more than previous generations of authors could have done."
Twitter has been a playground for storytelling experimentation before. The New Yorker magazine carried out a high-profile experiment on the platform with author Jennifer Egan, who tweeted installments of her story "Black Box," before the magazine published it in its entirety last May.
Comedians routinely have used the platform to tell stories or share vignettes in installments. Last fall, writer and actress Mindy Kaling posted a string of fictional observations about New York Fashion Week.
"Took off heels and pretended to be Malia Obama to sit in front row at Prabal Gurung," she wrote at the time. The series of tweets also included mock details of a dramatic faux romance with actor Adrien Brody. More recently, a parody account pretending to be New York Times polling analyst Nate Silver tweeted a psychedelic election-night journey. One of those tweets: "I am islanded in a stream of stars. Motes of datum gleam overhead. Am I their projection, or are they mine?"
Some may cringe at the idea of subjecting literature to the sometimes haphazard and rapid-fire unpredictability of a Twitter stream, but even now-sprawling classics have fractured roots. Celebrated works like "Anna Karenina," "The Brothers Karamazov," "Madame Bovary," and much of Charles Dickens' work first reached readers in snippets published in newspapers. But one of the goals of this festival is not simply to replicate serializations of the print era.
"Just taking paper books and putting them online, there's something not-so-beautiful about that," said Yael Goldstein Love, a novelist and co-founder of Plympton, a new publishing house that specializes in serialized fiction. "Part of what is really exciting about the Twitter Fiction Festival is it gets writers all over the world to think of other ideas, ways the online-ness of it enhances the story."
Goldstein Love was one of the judges who picked participants in the festival and says she was struck by the kinds of narrative experimentation Twitter encouraged. She says one entrant described the way his story's tempo -- and in turn the frequency with which he published tweets -- would vary based on what was happening at any given moment in the story.
"This guy saying he would change the rhythm depending on how much action there was, that kind of blew my mind," Goldstein Love said. "That can have emotional resonance. These are the kinds of things we just don't even think about."
Since it launched in 2006, Twitter has become a space where people play with narrative conventions. While the platform's web origins make it part of the disruption that has turned the publishing world on its head, Goldstein Love sees the creativity generated on Twitter as a harbinger of good things to come for the industry.
"Especially seeing all these submissions -- some from established writers, some from people who have never published a word -- it really puts to death a lot of doom-and-gloom rumors," she said. "People are imaginative and people are excited about publishing. Publishing is going to have to change a great deal, but so long as people are brimming over with creativity, I'm not at all worried."
Ryan Chapman of Penguin Press echoed that sentiment, calling Twitter one of the "green shoots for narrative storytelling" that keeps him optimistic.
"Maybe it's something to do with the fact that Twitter's maturing into this new space where people are so used to seeing it as a news source or conversation source," Chapman said. "As a reader, Twitter's obviously a place where everybody's already gathering for exchanging news and conversation. If people can use it as another part of their toolkit to create stories, that's really exciting."
Labels: fiction, Twitter, Twitter Fiction Festival, twitter literature

subset: commoncrawl


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Laroo Thh (Feat. Brimstone & Mic Conn) - Lights, Camera, Action
Artist: LAROO THH feat. Brimstone, Mic Conn Song: Lights, Camera, Action Directed by: Gino Rocks
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When: Thursday night
Where: Rogers Arena
VANCOUVER -- Ever since being crowned the winner of the fourth season of American Idol, Carrie Underwood has been spinning a familiar and extremely popular yarn.
The unassuming, fresh-faced dreamer from Muskogee, Okla. is, perhaps more than original Idol winner Kelly Clarkson, the quintessential Idol representative, the one that encapsulates the "American Dream" spirit of the competition the most.
Her storyline was and remains made of the kind of mythical fluff that fuels the imagination and, seven years later, Underwood still wants us to witness the power of that dream and how she rose out of middle-of-nowhere America to become one of the biggest country/pop music icons of the past decade.
It's a story woven deep in her four best-selling albums, including her latest Billboard-topping, steamrolling unit-shifter Blown Away, as well as in her concerts, which are reminders of how lucky and blessed she feels and how - if they believe hard enough - it could happen to any of the thousands of screaming fans that filled Rogers Arena Thursday night.
View more photos from the show here
That's the archetypical story Underwood has groomed and maintained for years, but as opposed to Clarkson's "anger management" style or Taylor Swift's "my exes are all jerks, so whatever" songbook, Underwood exudes a certain kind of wise maturity that doesn't feel forced or contrived.
Yes, it can be slightly overblown in concert, and you can chalk that up to Underwood wanting to deliver as much of an experience for fans as possible.
(But as opposed to someone like Madonna, whose concert last week was mostly flash and little substance, Underwood performs as if she isn't owed anything as much as she knows she owes her status to her fans.)
Kicking off with a Wizard of Oz theme (Oklahoma style rather than Kansas), with Underwood quite literally being "blown away" by a tornado in a quick movie intro, the blonde bombshell appeared popping out in the midst of kaleidoscopic, 2001: A Space Odyssey-style projections singing hit single Good Girl, with her cowboy/cowgirl gear-clad fans going wild.
Garbed in a sparkly white dress, Underwood upped it up a notch with rocker Undo It, the small town/farm backdrop coming back into play for Wasted.
The Wizard of Oz and Alice In Wonderland themes have been quite popular lately with female performers (Lady Gaga, Pink, Katy Perry) but Underwood's take on the "wide-eyed girl lost in a strange land" concept was more subdued, with a focus on the songs, many of them not as innocent as one may think. Two Black Cadillacs, on which Underwood really shined, is about two scorned women passing each other at the funeral of their common lover.
Backed by a solid eight-piece band, Underwood showcased her Idol-winning pipes, soaring high on an Emerald City-themed I Told You So.
Underwood's critics often cite her sizable team of handlers and the somewhat pre-fabricated, overwrought nature of her songs.
While some of the accusations leveled against Underwood are warranted (she is, after all, a huge money-making machine), the concert, with its carefully planned 20-plus song setlist, was a blast.
Favourites Last Name and All-American Girl (with its nod to Canadian hubby and hockey player Mike Fisher) had the crowd going bonkers, and rightfully so.
Underwood had the entire arena singing Jesus Take The Wheel, the 29-year-old grinning from ear to ear before floating over the audience on a platform with her band, as if carried aloft by hot-air balloons, singing Get Out Of This Town, Nobody Ever Told You and Thank God For Hometowns, all salutes to Muskogee and Vancouver.
The concert dragged a bit on the trip back, but it was nothing a few giant beach balls and confetti couldn't fix.
Underwood pulled a neat trick by bringing Brad Paisley on stage via LED projection to do Remind Me, and opener Hunter Hayes also showed up for Leave Love Alone. A cover of Sweet Emotion, however, would've benefited from the real Aerosmith.
In the end, it was a massive singalong for Before He Cheats, with a city landscape glittering in the background, that would prove to be the highlight of the night.
Opening, youngster Kira Isabella, who hails from Ottawa, had an unforgivingly short 20 minutes to make a good impression, and she did her best to make the most of it, wrapping up with a medley that included U2's Where The Streets Have No Name.
Rising country music star Hunter Hayes performed an effective -- if slightly bland -- set of material culled from his self-titled debut released a year ago.
The 21-year-old can be applauded for, like Underwood, writing or co-writing most of his material (he apparently played all the instruments and sang all the vocals on his album as well).
It would be tempting to label him country music's Justin Bieber considering he has been performing since he was four, appearing on Maury and Rosie O'Donnell's TV shows, and more importantly because the people that reacted loudest were the young female fans in attendance.
Hayes sometimes got pitchy (on Wanted and on a rather soulless cover of Bruno Mars' Just The Way You Are), but give the kid credit for at least playing and singing everything himself.
Blog: vancouversun.com/awesomesound


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I looked at the date of the last post and was saddened. I realized that the last post was 24 Feb. In addition, I was the last poster! People, our blog is suffering. Do we not experience still? Have we not the urge to share our personal ramblings and inner monologues? Perish the thought for the day has arrived that we cease to live and share! I beseach thee! Return to the blog and breath life yet into this wilting flower. My belief in you is strong, for you hold the key that will unlock the treasure that is our blog.
I just watched both seasons of the Tudors - forgive me.
Anyway, if you want to send cookies or other "goodies" to a friend/brother/son/uncle/cousin/citizen soldier who is at Fort Hood, TX his address is:
Jelani Berry
Battalion Judge Advocate
Building 56413
North Fort Hood, TX 76544
Lest you revive your once cherished notions for the blog, you shan't see my dispatch.
Monday, May 11, 2009
Posted by The Maharaja at 6:32 PM 0 comments
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Set up restricted areas with access only for privileged users in Trac 0.10.x
The RestrictedAreaPlugin is a pretty simple Trac plugin that allows the Trac administrator to set up restricted areas which are accessible only for privileged users in Trac 0.10.x installations. The access is controlled via the new Trac action
RESTRICTED_AREA_ACCESS and a list of paths configured in the Trac
IMPORTANT WARNING: Don't use the plugin for trying to hide sensitive data! The plugin is only a very simple protection against viewing Trac pages with restricted access! As pointed out by #2116 and #2364 not all parts of a restricted area can be restricted from visibility. With enough efforts it is thus possible to view all parts of a restricted page without the need of direct access to it. Unfortunately it isn't easily possible to further restrict access with Trac 0.10.x.
The plugin is tested only in our Trac environment which is a version 0.10.3 installation and in a 0.10.4 installation; it's known to not work with version 0.10.2 (cf. bug #1184) and will probably not work with earlier versions either. If you are running the plugin successfully in any other installation than the ones mentioned, then please edit this page accordingly -- alternatively file an informational ticket and I'll add the information myself ;-) Thanks!
Hint: For the newer Trac versions (0.11 and higher) the plugin will probably not work. But here the plugin should not be needed anyway as Trac has a fine-grained permission system included by default since 0.11. Head over to the SecurityBranch for more information on this.
Bugs/Feature Requests
Existing bugs and feature requests for RestrictedAreaPlugin are here.
If you have any issues, create a new ticket.
Download the zipped source from here. The plugin is licensed under the revised BSD license.
You can check out RestrictedAreaPlugin from here using Subversion, or browse the source with Trac.
To enable the plugin, add the following line to the
[components] section of your Trac
restrictedarea.filter.* = enabled
If you don't explicitly set anything, the path
/wiki/restricted has restricted access only. Usually, however, you will specify your own restricted areas via paths in the Trac
INI-file. Therefore you add the
[restrictedarea] section with paths specified in the following form:
[restrictedarea] paths = /wiki/secret, /wiki/area51
Finally you have to add
RESTRICTED_AREA_ACCESS action permissions to each subject (users or groups) that may access the pages below the specified paths -- just like you would do with any of the Trac built-in actions.
Recent Changes
Author: Chriki
The plugin was originally inspired by the HttpAuthPlugin. It was developed at the German Research Center for Artificial Intelligence, DFKI by me, Christian Spurk. Suggestions and feedback are always welcome; please note, however, that the plugin is my very first Python work and was developed during my first few weeks of contact with Trac. That means I'm neither a Python nor a Trac guru at all, so if you suggest enhancements to the plugin, then it would help a lot to give me some hints on how to implement certain things.
Finally if you're successfully using the RestrictedAreaPlugin I'd be happy to hear from you; just drop me a line, so I can see the plugin is appreciated and actually useful for someone -- thanks in advance :-)


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This post is part of our #DearMayor series. Join the discussion by tweeting us using the #DearMayor hashtag. We'll be bringing your responses to our continuing political coverage, and to our April 22nd mayoral debate!
1:43 p.m.: French toast and thanks
We're wrapping up our #DearMayor chat for today. We heard quite a lot from area residents, which we'll be reading over in the coming weeks as we approach the April 22nd mayoral debate.
We'll keep you posted on future cafe town halls. Meanwhile, we want to extend our deep thanks to Westchester's Coffee Company for hosting us. We're now about to finish off the afternoon with one of their famous French Toasts.
1:20 p.m.: Blight and business in South LA
Fixing potholes, fighting blight and providing jobs are common concerns we've heard this morning.
Trudy Goodwin of South Central told us she thinks the area needs the next mayor to help plan revitalization efforts.
"I'm very concerned with revitalizating those impoverished areas, those blighted areas of South Central, she says, "And also bringing in more jobs for young adults and high school children."
Valerie Doby, too, tells us the next mayor should focus on rebuilding parts of South L.A. that are still struggling after the '92 Riots.
"After the [92] Riots, there just hasn't been a lot to do in that part of Los Angeles. There aren't a lot of restaraunts the grocery stores are not great and the people in those areas really need the opportunity to shop and eat in their community."
Ginneh Smith of South L.A. was more specific about where she's seen pothole problems nearby.
"We have a lot of potholes and streets that need attention, especially the century corridor from Century and Crenshaw all the way down to LAX. We also have a lot of potholes between Florence and Slauson [avenues]."
Full audio:
RELATED: Your #DearMayor responses
1:38 p.m.: Dear Mayor, Airport issues are high on Westchester residents' minds
We heard earlier today from Paul Coony about his concerns with the planned expansion of LAX deeper into Westchester. That issue seems to be on the mind of a number of area residents.
John Frost came to talk to us about his worries that an expansion would endager residents' health and cramp traffic.
"They can spread these airports out," he says. "Use Ontario and Palmdale and other areas."
Westchester resident Sandra Bray echoed those concerns saying she wants the next mayor to to "take a stand" against LAX's planned expansion:
Marco Ramos, an LAX employee and 29-year Westchester resident, echoes both of their concerns, along with beautifying the neighborhood.
11:00 a.m.: Dear Mayor, Let's talk about diversity
Shirley Sher has concerns about the air quality, the local economy and education, but she also brought up an issue we haven't heard a lot about in this election - inter-ethnic and race relations in the city.
"I know that LA is full of immigrants and people of different backgrounds," she says, "but there still is a lot of hate crimes there's still a lot of intolerance. We'd just like to see L.A. become more mixed instead of … separate, people living in separate neighborhoods."
Shirley went on to tell us she felt that the mayor could help in that effort by raising awareness of the issue and getting different communities to talk.
What do you think? Are race/ethnic relations something you think the city and its mayor need to address, or has the urgency faded in recent years?
RELATED: #DearMayor: Share your thoughts on what LA's new mayor should focus on first
10:15 a.m.: Education Education Education
We've heard a lot from parents, students and teachers about their concerns regarding education funding. The mayor doesn't have direct control over the city's schools, though she or he can us their clout to influence the direction of L.A.'s school system.
Ella Kazemi, current owner of the Coffee Company where we recorded today's #DearMayor discussion, tells us she wants to see the next mayor to continue to focus on funding city schools and after-school programs.
Cafe-goer Durshawn Dennis and Twitter follower Franklin Burris, below, agree:
#DearMayor, pls add more after-school programs—Durshawn Dennis @wendy_greuel @ericgarcetti twitter.com/AshleyAlvarado…— Ashley Alvarado (@AshleyAlvarado) April 16, 2013?
@kpcc @ericgarcetti @wendy_greuel education is a cornerstone of any innovation economy and strong families— Franklin Burris (@FranklinBurris) April 16, 2013
9:45 a.m.: Dear Mayor, It's still about jobs
Clarence Scott had a few concerns for L.A.'s incoming mayor including fixing the streets and hiring more LAPD officers, but the most important issue, he feels, is creating jobs.
"There's a lot of people unemployed," he says. "If we can get more jobs we can boost the economy. and I think we'd be on our way. "
L.A. (and Southern California in general) has lagged behind much of the nation in recovering from the recession.
9:20 a.m.: Dear Mayor, Guns are in the news and on voters' minds
Deborah Favorite, a self-described progressive liberal activist, tells us she's looking for mayoral leadership on gun control, and assault weapons in particular.
8:45 a.m.: Dear Mayor, What's your plan for LA's water resources?
Toni, Arinsberg, the former owner of The Coffee Company, came by to share her concerns with the way L.A. currently handles its water resources.
"From what I understand," she says, "Los Angeles is currently purchasing water from Orange County -- reclaimed water, cleaned water. Whereas water in Los Angeles is just being taken right out to the ocean and dumped."
Toni also brought a few pictures from the Coffee Company's and KPCC!'s past. Free coffee for the first person to get the name of KPCC reporter at the right of this shot.
8:20 a.m.: Dear Mayor, Focus on public transportation and education
Public education and transportation have come up in many of our #DearMayor conversations.
Dominick Martin is one of those we spoke to this morning. He says the candidate with the best education and transportation plans will win his vote.
8:00 a.m.: Dear Mayor, take your own medicine
LAX employee Michael Quiles says he wants the next mayor to protect city employee benefits.
He says he wants to see the next mayor commit to sharing in the pain of public employees by taking cuts in salaries alongside public workers.
7:30 a.m.: Dear Mayor, Keep your promises!
Reporter Frank Stoltze kicked off this morning's talk with Paul Coony, an attorney and longtime resident of Westchester. He says it's important to him that candidates honor their campaign promises.
"For example," he says. "I recently switched allegiance from one candidate to another because one of them had the courage to make a commitment to an issue that's very important to me here in Westchester and that has to do with the expansion of and the removal of the North runway to a place 300 feet north of where it currently exists."
The expansion of the airport is of great concern to residents in Westchester as it will likely affect a number of homes.
7:00 a.m.: Coffee's on!
We're here at The Coffee Company in Westchester to hear what you think the next mayor should focus on first.
If you're in the area, come over and have a coffee with us, or tweet us using the #DearMayor hashtag.
We'll be bringing your responses to our continuing political coverage, and to our April 22nd mayoral debate!


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AL-QOSH, Iraq - Iraqi Kurdish fighters backed by US warplanes retook the country's largest dam from militants on Sunday, as Sunni Arab tribesmen and security forces fought the militants west of Baghdad.
The recapture of Mosul dam marks the biggest major prize clawed back from Islamic State (IS) militants since they launched their offensive in northern Iraq in early June when they swept Iraqi security forces aside. IS militants, who have declared a "caliphate" straddling vast areas of Iraq and Syria, also came under air attack in their Syrian stronghold of Raqa on Sunday, a monitoring group said. Syria's air force carried out 16 raids on the city of Raqa and several more on the town of Tabqa in Raqa province, killing at least 31 jihadists and eight civilians, said the Syrian Observatory for Human Rights. Two months of violence have brought Iraq to the brink of breakup, and world powers relieved by the exit of divisive premier Nuri al-Maliki are sending aid to the hundreds of thousands who have fled their homes as well as arms to the Kurdish peshmerga forces.
Buoyed by the air strikes US President Barack Obama ordered last week, Kurdish forces are fighting to win back ground they had lost since the start of August, when the jihadists went back on the offensive north, east and west of the city of Mosul, capturing the dam on August 7. Earlier Sunday, US warplanes and drones pummelled the militants fighting against the Kurdish advance.
The US Central Command reported that the military had carried out 14 air strikes during the day near the dam, which, located on the Tigris river, provides electricity and irrigation water for farming to much of the region. CENTCOM said the strikes destroyed 10 IS armed vehicles, seven IS Humvees, two armoured personnel carriers and one IS checkpoint.
An AFP journalist saw towers of smoke rising from the area of the dam, apparently from the sites of strikes. In Syria's Raqa, the air strikes were the "most intensive" against the IS since the jihadists joined the anti-regime revolt in that country in spring 2013, the Observatory said. "The regime wants to show the Americans that it is also capable of striking the IS," said the Britain-based group's director, Rami Abdel Rahman. In western Iraq's Anbar province, security forces backed by Sunni Arab tribal militia, who announced a new effort against the jihadists on Friday, made gains west of the provincial capital Ramadi, police said. Fighting was also taking place near the strategic Euphrates Valley town of Haditha, located near another important dam, police Staff Major General Ahmed Sadag said.
The rallying of more than two dozen Sunni tribes to the government side marked a potential turning point in the fightback against the jihadists and their allies. The militants were able to sweep through the Sunni Arab heartland north and west of Baghdad in June, encountering little effective resistance, and Iraqi federal security forces have yet to make significant headway in regaining ground. Anbar was the birthplace of the Sahwa, or Awakening, movement of Sunni tribes that from late 2006 sided with US forces against their co-religionists in Al-Qaeda, helping turn the tide against that insurgency.
In the north, members of minority groups including the Yazidis, Christians, Shabak and Turkmen, remain under threat of kidnapping or death at the hands of the jihadists. On Friday, IS fighters killed around 80 Yazidi Kurds in the village of Kocho near the northwestern town of Sinjar, Kurdish officials said.
The jihadist' storming of Sinjar on August 3 sent tens of thousands of civilians fleeing onto Mount Sinjar, prompting an international aid operation and helping to trigger the launch of US air strikes. The Yazidis' non-Muslim faith is anathema to the Sunni extremists of IS. Human rights groups and residents say IS fighters have been demanding that religious minorities in the Mosul region either convert or leave, unleashing violent reprisals on any who refuse. Amnesty International, which has been documenting mass abductions in the Sinjar area, says IS kidnapped thousands of Yazidis in this month's offensive.
Tens of thousands have fled, most of them seeking refuge in areas of northern Iraq under Kurdish control, or in neighbouring Syria.


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Adora 5.3 cu. ft. Electric Range with Self-Cleaning Convection Oven in Black Slate, Fingerprint Resistant
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REDLANDS, CA – Hangar 24 Craft Brewery, one of the top 100 craft brewers in the country, has expanded its California footprint to now include Northern Los Angeles and Ventura Counties and its famed Central Coast. Previously only available in Southern California, the nearly five year-old craft brewery offers 30 different styles of beer across seven categories.
"Hangar 24 continues to grow and we are excited to see people resonate with the brand," said Founder and Master Brewer Ben Cook. "I am incredibly proud of the hard work that our team has contributed over the past five years, including our brewery staff, sales team and distributors. We've all worked together to get us where we are today."
Hangar 24 is now available in Ventura, San Luis Obispo, San Benito and Santa Clara counties, in addition to already being featured in Los Angeles, Orange, Fresno, Kern, Kings, Riverside, San Bernardino (home of the brewery) and San Diego counties.
Hangar 24's current craft beer offerings are categorized by style in groups including, but not limited to:
- Year Round Offerings — Hangar 24's seven core beers, offered throughout the year
- Seasonal Offerings — The perfect beer for each of the four seasons
- Local Field Series — Each release features an ingredient grown in Southern California, including citrus, dates, red wine grapes, pumpkins and more
- Barrel Roll Series — Barrel aged beers available in very limited quantities Some of Hangar 24's craft beers that are currently available include, but are not limited to:
- Orange Wheat — American Wheat Beer brewed with whole, pureed, 100 percent locally grown oranges added throughout the process
- Amarillo Pale Ale — American Pale Ale dry hopped with Amarillo hops with an assertive hop flavor and aroma with a hint of caramel in the background
- Alt-Bier Ale — Northern German Ale with a caramel dominated flavor, bready/toasty finish, followed by a roasty flavor to dry it all out
- Hullabaloo (Seasonal, November-February) — A Scottish Ale brewed with American and English hops
For a full list of on and off-premise locations carrying Hangar 24 craft beer, please visit http://www.Hangar24Brewery.com/findbeer.htm. For a complete list of Hangar 24's craft beer styles and categories, please visit: http://www.Hangar24Brewery.com/currentofferings.htm. For distribution inquiries in Northern Los Angeles and Ventura Counties please contact Allied Distributing at (818) 362-9333. For distribution inquiries in California's Central Coast, please contact Central Coast Distributing at (805) 922-2108.
About Hangar 24
Hangar 24 Craft Brewery began with a true passion for good beer, the absolute love of flying and the pure enjoyment of being around great friends. Owner and master Brewer Ben Cook and his buddies used to meet at Hangar 24 after an afternoon of flying to trade stories, talk aviation, play music and share a few cold ones that Ben just finished brewing at home. These days, the location where these fine beers are brewed has changed, but the quality time spent enjoying a delicious, handcrafted beer and conversation is the same as ever. Hangar 24 Craft Brewery employs more than 50 team members and its distribution is now spanned throughout Southern California with its addition of another company, Hangar 24 Craft Distribution. Its annual capacity now stands at approximately 40,000 and its Brewery and Distribution Center together employ nearly 100 people.


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Sandra Bullock and the five stages of grief
June 30, 2009
I had never walked out on a movie, and I wasn't starting now.
The following is a true story. The names of the people involved are changed, the names of the movies involved aren't.
Sunday. 4:38 p.m. In one hand I hold my soda; the other, two tickets for the 4:40 p.m. showing of "The Hangover," and my cell phone with an open text message thread.
Me (2:15 p.m.): I'll be at the theater at 4:30 p.m.
Tara (2:16 p.m.) : All right.
Me: (4:36 p.m.): I'm in the lobby. Already got tix.
Tara (4:38 p.m.): Almost there.
A few minutes later, the almost is gone. We enter the already-darkened theater where the 4:40 movie is now showing. We are the late people I normally loathe.
Trailers for bad movies show. Sarcastic comments follow. And then silence, for "The Hangover" is about to start. The summer's breakout comedy starts at an office building, with ... Sandra Bullock on an exercise bike?
As an aside, I do not hate Sandra Bullock movies. I just don't particularly like Sandra Bullock movies. There are many things I'd rather do than watch a Sandra Bullock movie, and at the top of Sunday's list was "Watch the movie I paid to see." I required no romantic ending.
The stages of grief set in. Denial comes first.
"Wait, Sandra Bullock's in 'The Hangover,' too? So is Ryan Reynolds? Thought I would have heard something about that."
The words, "The Proposal" come up on the screen. Anger comes next. I'm tempted to lash out at Tara for showing up late so we didn't have time to pick out a seat and ... oh yeah, not hurriedly walk into a theater where one could easily mistake "NOW SHOWING THE HANGOVER 440 PM" with "NOW SHOWING THE PROPOSAL 440 PM."
Tara took control of the bargaining. "Kevin, I kinda want to see this movie anyway. Assuming you're free the rest of the night, as am I, I'll pay for 'The Hangover' later tonight."
Depression was quick. For as much as I didn't want to see Bullock, there's something enjoyable about Ryan Reynolds given a chance to be a jerk. Basically, "Proposal" goes like so: The world's most demanding boss (Bullock) is about to be deported to Canada, but she forces her assistant (Reynolds) to marry her and they have to take a trip to his family's house in Alaska to break the news and try to convince an immigration agent they're in love and not defrauding the government.
Soon after, acceptance sets in. I walked us into the wrong theater, and I do not have the moral high ground on Tara here. During a dinner break between the movies, I texted Lacey, who recommended I watch "The Hangover" because I knew she'd love an embarrassing story. And I told friends online, noting they would have become millionaires if they could have bottled up the sense of defeat I felt when Bullock appeared on screen at 4:50 p.m.
A friend writes back, "That's nothing. I had a friend whose wife took him to '28 Days Later' (British zombie movie) thinking it was the sequel to '28 Days' (Bullock movie about a big-city reporter who checks into a quaint drug rehab center).
I'm guessing she didn't get a romantic ending either.
Kevin Wilson is a columnist for Freedom New Mexico. He can be contacted at 763-3431, ext. 313, or by e-mail: [email protected]


text:
M&T Bank must forfeit $560K in drug proceeds
Feds: Drug money laundered through branch in Perry Hall
A federal judge in Baltimore is ordering M&T Bank Corp. to forfeit $560,000 in drug money laundered through a branch in Perry Hall.
U.S. Attorney Rod Rosenstein announced the forfeiture Wednesday.
The judge found that the bank failed to file reports on at least eight currency transactions in which a teller converted proceeds from illegal drug sales from small denomination bills into $100 bills.
Former head teller Sabrina Fitts was sentenced to a month in prison for failing to file currency transaction reports on suspected drug proceeds. Fitts also must forfeit $5,000 she was paid by customer Deanna Bailey to do the conversions.
Bailey was sentenced to 46 months in prison for money laundering conspiracy.
The bank said that its cooperation with law enforcement helped in the prosecution and recovery.


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From the Baron & Baroness
Unto the Populace of Rowany do Baroness Ameline and Baron Miles send warmest greetings.
It has been an exciting month! And a busy one. It has been great to see so many of you at events both near and far.
A month ago, we stepped up as Baroness & Baron. This was a wonderful event stewarded by Sigvald and team. We were especially impressed by the delicious repast created by Lady Tatya and her team, created in such difficult conditions. Thank you also to Lady Annabel for her organisation of the Agincourt carol. We were also very pleased to witness the elevation of Mistress Clara van de Maes to the Order of the Laurel.
In the last month we have had two demos, one at the Blacktown Medieval Fair, and more recently, at Supanova. Great thanks to Skarpathan for his organisation of these, and all of those who volunteered their time. We had a great time at the Blacktown demo, and it was good to be able to include Combat Archery in the display for the first time.
We were pleased to accept the kind invitation to attend Dismal Fog's Panther Hunt event. This was an archery focused event. It was good to see members of our Barony travelling to visit our near neighbours. Special thanks to the Bunny Rabbit, the Dragon & the Panther.
Further afield, we also travelled to Great Northern War. The Northern Reaches as always put on a wonderful event, and we are sure that those others from Rowany who travelled there also enjoyed it as much as we did. Lots of good fighting, good company, and also lots of fire.
Last night we had our first Baronial event within our tenure, the Pheast of the Pheasant in our Canton of Okewaite. It was good to see many travellers from central Rowany & Stowe, and also some guests from Politarchopolis. Thank you to Cristoval for providing such marvelous food – including an item or two for the more adventurous to try. At this event we were pleased to recognise Lady Helouys of Politarchopolis with a Silver Cinquefoil for her work for the Barony, especially in Okewaite; also Lady Bella Rose of Okewaite for work on Flanders costume with Rowan Berries; and also recognising the exemplary courtesy of Baroness Alys Dietsch with the Order of the Dovetail.
In the next month, we will be travelling both to the Stormhold Investiture on the 21st of June, and Midwinter Coronation in Politarchopolis on the 5-6th of July. Closer to home, the College of St Ursula is hosting College War at Glenfield, and also Stowe on the Wowld will be holding their Ludi Natalis Birthday Feast on the 19th of July. We hope to see many of you at these events.
In Rowany's new monthly A&S Challenge and Display, as organised by Mistress Clara, in the month of June we are looking at both Cooking and also Music – two great categories that we hope to see many members participate in. July will follow with Plants & Herbs, and Textiles & Fibre Arts – so start thinking about what you might like to try for those areas as well.
We are currently working on getting the Barony's award records into a form that they can be displayed on the website. Please don't forget to recommend to us those members of the Barony that you feel are worthy of recognition.
Ameline et Miles


text: Academics / Sparer Public Interest Law Fellowship print Sparer Fellowship Committee Overview Fellowship Program How to Apply Public Interest Curriculum Meet the Sparer Fellows Sparer Fellowship Committee Symposia and Forums Publications Sparer Alumni Fellows Mentoring our Sparer Fellows The Sparer Fellowship Committee, under the leadership of its founder and Director, Professor Elizabeth M. Schneider, is an outstanding group of faculty with a strong commitment to public interest law. Their prior work experience, and their scholarly and teaching interests reflect a diverse range of public interest work. The Committee members serve as advisors and mentors to the Sparer Fellows. Elizabeth M. Schneider, Director, Sparer Public Interest Law Fellowship Program and Rose L. Hoffer Professor of Law Professor Schneider, director of the Edward V. Sparer Public Interest Law Fellowship Program, is a national expert in the fields of federal civil litigation, procedure, gender law, and domestic violence. The New York State Coalition Against Domestic Violence honored Schneider as one of 30 leaders making a difference in the lives of survivors of domestic violence. She served as a consultant for the Secretary-General's Report on All Forms of Violence Against Women, which was submitted to the General Assembly of the United Nations. Jonathan Askin, Associate Professor of Clinical Law Professor Jonathan Askin founded the BLIP Clinic when he joined Brooklyn Law School in 2008, bringing more than a decade of experience in the communications industry from both the public and private sectors. He has served as president and general counsel for the Association for Local Telecommunications Services and was a senior attorney at the Federal Communications Commission. He is actively involved in developing Brooklyn as the 21st century "Silicon Alley," recognizing the borough as a burgeoning hub for innovative start-ups, and is affiliated with the Dennis J. Block Center for the Study of International Business Law. Debra Bechtel, Associate Professor of Clinical Law Professor Bechtel teaches clinical courses that address a range of corporate, community and real estate topics. One of New York's foremost experts in low-income or limited equity co-ops, she has written for the ABA Affordable Housing Journal and speaks often on community development issues. She is the co-chair of the New York State Bar Co-op and Condo Committee's Subcommittee on Affordable Housing. Stacy Caplow, Associate Dean of Professional Legal Education and Professor of Law Professor Caplow is the director of the Law School's Clinical Education Program and co-director of the Safe Harbor Project. A leader in the field of clinical legal education, she has worked abroad to help augment the clinical curriculum for LLB and LLM students at the University College Cork Faculty of Law, and with a refugee center in Cork. Caplow also spent a semester at the University of Hong Kong helping to establish its first legal clinic. Elizabeth Fajans, Associate Professor of Legal Writing Professor Fajans is the Law School's writing specialist. Her book, Writing and Analysis in the Law, now in its fifth edition, is the most widely used first-year legal writing text for law students. Linda B. Feldman, Director of the Academic Success Program and Associate Professor of Academic Support Professor Feldman is the director of Brooklyn Law School's Academic Success Program. She is a former chair of the Association of American Law Schools' Academic Support Section and is currently on that section's nominating committee. A frequent presenter on issues of academic support, she has spoken at the Law School Admission Council Conference and at various workshops. She serves on the executive committee of a not-for-profit organization providing housing and support services for the recently homeless. Cynthia Godsoe, Associate Professor of Law Professor Godsoe co-created and co-teaches a public interest law class, highlighting various models of public interest lawyering and ethical issues confronting attorneys in this field. She also discusses public interest law in her Children and the Law and Professional Responsibility classes. Godsoe is an expert in children's rights, education and juvenile justice issues. Prior to teaching, she engaged in impact litigation and direct services at a number of organizations including Advocates for Children and Legal Aid. Godsoe was awarded a Skadden Fellowship upon graduation from law school and currently chairs the Juvenile Justice Committee of the New York City Bar. Susan N. Herman, Centennial Professor of Law Professor Herman is a nationally-recognized expert on the U.S. Supreme Court and constitutional law. She is the president of the American Civil Liberties Union, an organization she has worked with for over 25 years. As a constitutional law specialist, Herman has written books and numerous articles on civil liberties issues, including the due process rights of prisoners, the Patriot Act, the Fourth Amendment, socioeconomic rights and equality, and the First Amendment. She is a regular commentator in the media. Minna Kotkin, Professor of Law Professor Kotkin is the director of the Brooklyn Law School Employment Law Clinic and teaches New York Civil Practice. She has taught civil procedure, aministrative law, civil rights law, and interviewing and counseling. She has written and lectured extensively on issues of employment discrimination and clinical legal education. Rebecca Kysar, Professor of Law Professor Kysar teaches and researches in the areas of federal income tax, international tax, legislation, and statutory interpretation. Her recent scholarship examines the tax legislative process and has appeared in several prominent journals. Prior to joining Brooklyn Law School in 2008, Professor Kysar practiced at Cravath, Swaine & Moore, where she was responsible for the tax aspects of complex domestic and international transactions. Samuel K. Murumba, Professor of Law Professor Murumba teaches and writes in the fields of international human rights and intellectual property. A refugee who fled the regime of Ugandan dictator Idi Amin, he continues his lifelong commitment to human rights. Murumba was recently honored by Human Rights Watch for his decades of service to the organization, including as a board member and advisor to the Women's Rights Division and the Africa Division. He is an Advocate of the High Court of Uganda and of its subordinate courts. David Reiss, Professor of Law Professor Reiss concentrates his scholarship on real estate finance issues and is well known for his research on the subprime secondary mortgage markets. Reiss directs the Community Development Clinic, which represents development corporations, cultural institutions, affordable housing providers, and small businesses that serve under-represented communities. He serves on the boards of several local organizations. Dan Russell Smulian, Associate Professor of Clinical Law Professor Smulian teaches the Safe Harbor Clinic, in which students represent individuals in a range of cases affecting their status and entitlements in the United States. He has a strong background in public service lawyering. He served as the director of training and legal services at the New York Immigration Coalition, managing a statewide program that provides seminars and educational events on immigration law and immigrants' rights issues for immigrant communities. Previously, he was associate director for legal services at Catholic Charities Department of Immigrant and Refugee Services. Winnie Taylor, Professor of Law Professor Taylor is an authority on consumer law, contracts, and credit and employment discrimination. For the past 30 years she has served as a consultant for Fair Lending and Workplace Equity, focusing on equal credit opportunity and equal employment opportunity laws. She has written extensively on the federal Equal Credit Opportunity Act and is a former member of the Federal Reserve Board's Consumer Advisory Council. She also participated as an instructor in a Federal Trade Commission program to train its attorneys on fair lending and other consumer banking issues. Nelson Tebbe, Professor of Law Professor Tebbe teaches constitutional law, religion and the law, and professional responsibility. His scholarship focuses on the relationship between religious traditions and constitutional law, both nationally and internationally. His articles have appears in numerous law journals and he is the Chair of the Law and Religion Section of the Association of American Law Schools. View photos from the Sparer Celebration. Related Links: Law Journals Public Interest Law Curriculum Student Organizations Fellowship Application Pro Bono Brochure Have questions? We have answers. Sparer Fellowship Program Marva Skeene Brooklyn Law School 250 Joralemon Street, Room 800A Brooklyn, New York 11201 Telephone: (718) 780-0351


text:
Bangor, Maine, mental health liaison, officer, allegedly assaulted in domestic abuse response
BANGOR, Maine (AP) � Bangor police say a mental health liaison and an officer were allegedly assaulted while responding to a domestic abuse case in the Maine city.
Officer Tim Shaw says a struggle broke out as he was trying to arrest 24-year-old Anthony King of Bangor on a domestic assault charge and handcuff him. Shaw says King attempted to choke him. A city mental health officer tried to help Shaw during the struggle.
Shaw says he and the mental health liaison were punched and kicked several times before Shaw threatened to use his Taser on the suspect. At that point, King gave up and was handcuffed.
King's been taken to Penobscot County Jail in Bangor, where he faces assault on a police officer, domestic assault, terrorizing and other charges.


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- Description
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Getting a new set of bedding is a great way to give your bedroom a mini-makeover and give yourself the warmth and comfort you want.
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Through dance, mime and puppetry, the company of six Siro-performers interact with technology in a way never seen before. Featuring spectacular video projection, light animation, stunning laser effects and a pulsating electro beat, SIRO-A is family entertainment like no other.
SIRO-A is fast becoming a worldwide phenomenon, having performed to 30,000 people at the Shanghai Expo and winning the Spirit of the Fringe award at the prestigious Edinburgh Festival. Now this visually stunning show is returning to London where it wowed audiences and critics on its previous go-round in February.
Siro-A is not available to book, please sign up to our newsletter for updates and offers on forthcoming and available shows.
Show times vary throughout the run.
Find out more about the venue for your show: Directions, Transport options and facilities.
The Leicester Square Theatre is two minutes' walk from Leicester Square tube station, and ten minutes' walk from Charing Cross mainline station.


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Park Slope Tanning & Airbrush salon offers an exceptional tanning experience in Park Slope, NY. It is accessible from Brooklyn neighbourhoods including Gowanus, Carroll Gardens, Cobble Hill, Fort Greene, Downtown Brooklyn, Sunset Park and Prospect Park.
Receive a beautiful glowing tan with six levels of UV tanning or sunless, UV-free airbrush tanning or spray tanning options. Park Slope Tanning Salon is top ranked by our regular tanners because of its superior tanning machines and great monthly tanning specials.
Also read our blog for tanning tips and visit us today at Park Slope!


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When we ring in the new year, we have no idea what unusual scientific discoveries will turn up. iStockphoto/Thinkstock
Scientists and researchers are always busy at work, hoping to create the next greatest consumer product, or identify a new species of mammal, or create a cure for cancer. Similarly, archeologists are constantly digging around to unlock secrets from the past. More often than you'd think, all of this hard work results in some pretty bizarre discoveries.
These discoveries don't come just at the hand of scientists, of course. Plenty of regular citizens have stumbled upon the craziest things. So what's been discovered in 2012? Lots of oddities, just like any other year. Here are 10 of them.


text:
1st Gear: Behold, you lovers of highly-decorated, ridiculously expensive, German/French tea sets. We've got a slew of new, official images (click here for the gallery!) of the Bugatti Veyron L'Or Blanc, a version of the recently updated Veyron with porcelain fittings by Germany's Konigliche Porzellan-Manufaktur Berlin (KPM). The one-off is reportedly worth $2.3 million.
2nd Gear: This week it emerged that the British newspaper, the News of the World, had allegedly accessed voicemails of murdered schoolgirl Milly Dowler. Now, after a prolonged Twitter campaign of about four hours, Ford has pulled all advertising from the News of the World over the ongoing phone tapping scandal.
3rd Gear: BMW is recalling 50 2011 X3s because a control module in the electric power-steering unit could malfunction, resulting in a sudden loss of power-steering assistance, according to the National Highway Traffic Safety Administration. "A control module in the electric power steering unit may malfunction, resulting in a sudden loss of power steering assistance," said NHTSA in its recalls summary of the problem. "Sudden loss of power steering assistance could increase the risk of a crash." In other documentation filed with the federal government, BMW said it "received 20 cases (regarding the defect) for the X3 worldwide." The defect, if left unchecked, will of course lead to potential fiery death!
4th Gear: Ford is planning to spend $600 million to overhaul a plant in Kentucky to produce a new model of its Escape sports utility vehicle. This version of the Escape would be built on the Ford Focus platform and look almost exactly like the Ford Vertrek concept showed at the Detroit Auto Show earlier this year. Because, you know, at Ford, all your cars are belong to Focus.
5th Gear: General Motors issued recalls to fix a faulty part on police versions of 2007-08 Chevrolet Impalas but ignored more than 400,000 U.S. civilian buyers, according to a lawsuit filed last week. The suit, which was filed in federal court in Detroit and seeks class-action status, alleges the vehicles were manufactured with defective rear spindle rods. The faulty rear spindle rods misalign the rear wheels, causing tires to wear out prematurely, the suit says. And as we all know, tires that have been worn out prematurely can lead to fiery death!
6th Gear: Metropolitan Lincoln in suburban Detroit, a dealership located less than nine miles from Ford headquarters in nearby Dearborn, has closed down after more than 50 years in business. The dealership cites Ford's move to discontinue the Mercury brand last year. The dealership, in Garden City, Mich., originally was Stu Evans Lincoln Mercury. It became Metropolitan Lincoln Mercury in October 2006. A statement on the dealership's Web site that was attributed to managing partner John Obeid said the loss of Mercury sales sent the dealership into a tailspin. The Mercury brand "accounted for about 70 percent of Metropolitan's new-vehicle sales," the statement said. The closing of Lincoln dealerships has been expected after the move by Ford to discontinue Mercury in 2010. At the time, Ford executives said eliminating the Mercury brand was a necessary step for the company to focus its attention on fewer brands.
⏎ Behind-the-scenes: James compares Porsches. [Top Gear]
⏎ Tesla Motors coming of age as an automaker [San Francisco Chronicle]
⏎ For Jaguar Drivers, a Letter Brings Its Privileges. [New York Times]
⏎ Is Ford the best American automaker? [CNBC]
⏎ Suzuki's Kei Cars, Running Mild in New Jersey [New York Times]
⏎ UK new car sales down 6.2% in June, in year-long decline. [MSN Autos UK]
⏎ Metro Detroit gas prices inching back toward $4. [Detroit News]
Today in Automotive History:
The great Argentine race car driver Juan Manuel Fangio, winner of five Formula One driver's world championships, competes in his last Grand Prix race—the French Grand Prix held outside Reims, France—on this day in 1958. [History]
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This female SIN 2353 metric threaded push style hose fitting has been designed and tested for use with our SAE 100R6 high temperature hose, to form a push style hose system.
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Enjoying a typical day of world-class fishing in Louisiana
By Craig Lamb
The fastest, safest and best-equipped boats in south Louisiana are docked just a few steps away from your luxury condo. Captain John Pisa, a veteran guide around Venice, Louisiana, is waiting for you to come aboard.
Untie the lines and head out the Mississippi River passes and you will be in the most gamefish-rich waters of the United States. Yellowfin tuna. Snapper. Grouper. Wahoo. Dolphin. And lately, there are swordfish.
That's a snapshot of a day of fishing with Home Run Fishing Charters & Lodge. Pisa and his fellow captains are the most knowledgeable guides in the area known as Tuna Town.
At typical day begins at 6 a.m. and concludes at 6 p.m. Offshore rates are $1,700 plus fuel costs for up to 6 anglers. Inshore rates are $800 for up to 3 people or another $50 for a fourth angler. Fuel, artificial and dead bait is included.
You will ride and fish in luxury from 36' Yellowfin 36 boats designed for smooth, dry rides in the blue water, and powered by a trio of fast, dependable 300-horsepower Yamaha outboards. What that means for you is a boat that skims across the water at 50 mph or more. You will be first to the best fishing, while arriving safely. You will fish from Shearwater and Skeeter boats for inshore trips.
Click here to view more about the offshore fleet of boats.
You'll use the best and latest tackle when aboard the boats. The gear can stand up to the toughest pelagic species in the sea, such as premium 30w and 50w stand-up gear and Shimano reels with Seeker Rods. For really deep fish the boats have Hooker electric reels.
Those will come in handy for the latest fishing craze in South Louisiana.
"Swordfish have gotten really popular, and recently we've hooked up with lots of big fish," said Pisa.
The swordfish are being caught from 1,300 t0 1,700 feet deep. Those electric reels make the work easier and more fun for fighting the big swordfish. Those are running up to 200 pounds.
The snapper season is what else is hot. The season begins June 1 and runs 48 days.
"We have a lot of customers who come for the snapper," added Pisa. "It's a short window, but the fishing is just exceptional."
Right now is prime time for experiencing the greatest variety of fishing around Venice. Take your pick from blue and white marlin, grouper, cobia, blackfin tuna, yellowfin tuna, and wahoo. Mangrove snapper, dolphin and king mackerel also are abundant.
"What's really great about a trip here is a lot of times you don't know what you're going to catch until you see it come up," added Pisa.
Click here for more about the offshore charters.
"We also have world-class inshore fishing for speckled trout and redfish," said Pisa.
Click here for more about inshore charters.
What sets Home Run Charters apart is the Home Run Lodges. The lodges are located within the very same marina where you will meet your captain and board their boat. You can have a tasty breakfast and be out the door and into the boat within minutes.
Ready to book a trip? Click here for more information on rates. Got questions? Click here for the FAQs. Need more information? Call (504) 909-TUNA.
Original Source: Sportsmans Lifestyle.com


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- The Step Up Your Speaking contest helped winner Stephanie Benoit's progress, but is a coaching program where all our readers can benefit.
- This blog's all about the preparation, and the Checklist for the Whole Speaker post -- a list that considers your intent, content, mind, body, wardrobe and technology before you set out to speak -- is a perennial favorite.
- You'll speak better if you gesture, and this post on the science behind effective gestures has become a regular reference for our readers.
- Conveying power is a key component of eloquence. No wonder these 6 strongest speaker statements are so well-read. Among them: "I don't know," one of the most powerful for any speaker.
- Questions can sometimes get your presentation off-track. Can you welcome questioners and manage Q&A at the same time? Our graceful ways with Q&A can help.
- Readers have a host of questions about the most important part of body language: eye contact. So we offered 5 eye contact tips for speakers, a perennially popular post.
- Storytelling's another critical skill for the eloquent speaker. In this post, you can see a top scientist demonstrate how to tell a story on yourself -- the most powerful stories are the most personal ones, I find.
- Can a tour guide be eloquent? I think so, and guiding tours is just one of many everyday situations where women have speaking opportunities. This post about my tour guide at the Martin Guitar Factory shares what you can learn from her.
- Readers and their questions inspire my best posts, and here, 7 readers offer you the best speaking advice that they've ever received--and put to actual use. Their tips cover Q&A, intros, practice, breathing, audience engagement, pacing and more.
- When the speaker needs to catch her breath, another reader-prompted post, looks at what's really happening when you go breathless while speaking--and what to do about it.
Inspiration, ideas and information to help women build public speaking content, confidence and credibility. Denise Graveline is a Washington, DC-based speaker coach who has coached nearly 200 TEDMED and TEDx speakers--including one of 2016's most popular TED talks. She also has prepared speakers for presentations, testimony, and keynotes. She offers 1:1 coaching and group workshops in public speaking, presentation and media interview skills to both men and women.
Saturday, August 14, 2010
New way to weigh in on Eloquent Woman blog posts
Look at the bottom of any blog post on The Eloquent Woman and you'll now see a new way to weigh in: Checkboxes that let you say "will try this," "afraid to try this," or "inspiring!" Try out the new buttons on these posts that are among the most popular with readers:
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It's hard for any other gaming app to shine when Rovio releases the first true sequel to the physics game that's captivated millions of fans across the globe. Good thing there's five Gaming App of the Day slots every week.
Now I'm not saying the makers of Star Warfare, MotoHeroz HD, Abduction! World Attack and TrafficWonder aren't deserving of their spots in our daily salute to mobile games; each has their own unique strengths and weaknesses that make them worth of the title of Gaming App of the Day.
I'm just saying I like gift baskets, though I am on a diet so I prefer fruit over chocolate. Or chocolate over fruit, since the fruit negates the calories.
If you have a suggestion for an app for the iPhone, iPad, Android or Windows Phone 7 that you'd like to see highlighted, let us know.
Star Warfare is Fighting Against Awful iPhone Controls
Look, for the most part, there's nothing terribly remarkable about iPhone shooter Star Warfare. Its visuals are nice, if hardly top-shelf in this post-Infinity Blade world. Its structure, while taking enough cues from Horde mode games to be enjoyable, isn't pushing the idea anywhere new. More »
Driving Through Traffic Jams Never Felt This Good
Some mobile games are built to be nothing but diversions, pointless timekillers for subway rides and doctors' appointments. Others are good enough to keep you up all night. More »
MotoHeroz HD Combines Racing and Platforming For a Fast, Fun Ride
Dev studio RedLynx created a genuine phenomenon with their physics-happy motorbike racer Trials HD. That Xbox 360 exclusive turned hordes of gamers into obsessive-compulsive stunt riders, trying to notch ever better performances out of their thumbs. More »
Angry Birds Space Slingshots Its Way Into Gaming App of the Day
You've read all about Angry Birds Space in our explainer article, now watch me play it as we officially give Rovio's latest and greatest a nod as our Gaming App of the Day. More »
Bouncing Cows to the Rescue in Abduction! World Attack
Abduction! World Attack is not new. It's not complicated. And it's not super HD. But it is silly, fun, cute, and addictive, which makes a great combination. More »


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HTC One Is a Winner
HTC One Review
Android phones are often criticized as flavorless. While they come in a variety of screen sizes with insides that differ even more, they generally all look and feel the same, with many differentiators (ooh, apps that scroll up and down instead of side to side!) actually not amounting to very much. Even the name "Android" implies easily replicated automatons.
That's why the HTC One ($199 for 32GB with a two-year contract on AT&T or Sprint, also on T-Mobile) is a refreshing change from all the bots out there. HTC has focused on a few standout features — including an interactive home screen, a retooled camera and a novel way to share experiences — to turn the One into a device that, well, stands out. None of those features is perfect, but at least the company is really trying to differentiate and not just "skin" things.
Take just one example: The HTC One can function as a TV remote control. The app is bland, and setting it up could be clearer, but it's a great feature to have. HTC had to build an infrared blaster into the power button on the top to enable the One to work as a remote, but that's definitely something you iPhone can't do.
HTC lent us a One for review, a pre-production unit that works on Sprint's network (I could tell it was pre-production since it kept telling me it was connected to "print"). Unfortunately, even though it's equipped to connect to Sprint's flavor of LTE, the network hasn't been switched on yet, so I was puttering along at much slower 3G speeds when separated from Wi-Fi.
Pretty One
You can tell the One is a high-end phone from its design. The exterior is crafted from a single piece of aluminum, which feels solid in the hand — although it's ever-so-slightly less grippy than plastic or glass. The 4.7-inch screen size strains the balance between convenience and unwieldiness ... your fingers will get a good stretch sometimes, at least.
The edge of the phone tapers in slightly toward the screen. This actually gives the phone a very distinctive feel; I would never mistake the One for, say, the Galaxy S III or even other HTC phones like the One S. Some well-considered chiseling along the edge helps to give your fingertips more traction.
The screen is a beautiful LCD with full HD resolution, 1,920 x 1,080 pixels. That puts its pixel density way north of "retina" at 468 pixels per inch (ppi) — not that it makes much difference to your eyes. The screen makes photos and videos look amazing, although I wouldn't expect anything less from a phone that calls itself a flagship.
The 4.7-inch display is on the large side, though. This isn't a monster phone like the Galaxy Note II, but it can be unwieldy sometimes — like when you need to create an app shortcut on the home screen. It's a straightforward process: Just press and hold the icon and drag it to the top of the screen, but that's sometimes a large distance to traverse with your thumb if you pick an icon lower down.
Like other HTC phones, the One carries the Beats Audio label. In this case, at least, it means a lot, since the One has some of the best — and loudest — audio I've heard from a cellphone. The front of the phone incorporates speakers both above and below the screen. I once held the phone at arm's length during a loud outdoor party and was still able to hear the Pandora station I was tuned to. Bonus: There's a built-in FM radio, too.
Snacking on BlinkFeed
The marquee feature on the HTC One is BlinkFeed. It's a big, visual feed of stories that serves as the One's default home screen. Once you set it up, it'll show you updates — basically photos, headlines and avatars — from any social networks (Facebook, Twitter, Fickr, etc.), apps (such as the Calendar and TV apps) and partner publications (including Reuters and The Huffington Post).
If that sounds a lot like Flipboard, you're not far off. BlinkFeed is designed to give you "snack-size" content that you actually care about from the moment you unlock your phone. In practice, it's not quite as elegant as Flipboard, although the scrolling animation is nice and inviting.
The difference comes in execution. With Flipboard, when you tap on a story, a preview comes up that's within the app's framework. With BlinkFeed, you're shunted to whatever app the story is from, or if it's a publication, to a newsreader. It's a subtle difference, but it leads to delays as you wait for Facebook and Twitter to launch before you see the content you want. And if you're offline, forget it (apps like Flipboard and Pulse hold some content in a cache).
There also isn't much control over how the content is presented. You can choose the networks and publications whose content you want to see, whether or not the feed auto-refreshes, and what region you want the stories to focus on. How often you see a particular network, or the size of the update windows isn't customizable.
You also can't delete BlinkFeed outright, although you can make any other screen your default home screen in lieu of it, and you technically never need to set it up. Also keep in mind, BlinkFeed is a 1.0 service, and improvements are sure to come soon.
BlinkFeed, like Facebook Home, is one of several recent stabs at making smartphones more personal by pushing apps aside to bring users content they ostensibly want. I prefer BlinkFeed's approach to Facebook Home's since it's inherently more democratic, although HTC might have done better if they simply partnered with Flipboard for the service. In any case, I like the idea.
Searching for UltraPixels
HTC removed itself from the megapixel race with the One, actually reducing the resolution of the image sensor from its previous generation of phone cameras. Why would they do that? Simple: to make the pixels themselves larger, what the company calls "UltraPixels," which is said to give the One's 4.3-megapixel camera advantages in low light and fast action.
By my eyes, HTC is really onto something here with UltraPixels. In a photo I took of my wife in our dim living room, I could pick out detail in her dark blue jeans as well as on our dark brown couch — detail that's often smeared out in shadow when inferior image sensors try to capture it. (Check out some sample shots from the HTC's camera below.)
HTC One Sample Photos
I also used the One to take dozens of photos of an outdoor toddler birthday party. As the kids ran around like crazy, jumping all over a bouncing castle, the One was a very capable action photographer, and I was able to snap several great shots.
However, for all the pics I took, I noticed slightly more graininess than I saw in photos taken by other phone cameras (mainly an iPhone 4S) in the same lighting — whether dim or bright. It was only noticeable when I viewed the pics on a bigger screen, but it was definitely there.
Perhaps the camera was choosing an ISO that was a little too high, or maybe it's just something inherent with a lower-res sensor. If most of your phone pics end up on Facebook or Twitter, you won't even notice. Overall, I found the image quality of the HTC One's camera to be very good.
Zoe Makes an Impression
With the One, HTC is introducing a new feature. It's called Zoe, and it's pretty cool. After you snap a bunch of photos — and maybe even a few videos — of any event (say, a hockey game), the phone will automatically create a short video compilation of them (using up to 13 individual pieces of media). It's essentially a slideshow that's about 30 seconds long, complete with canned music and optional Instagram-like filtering. Here's an example:
While apps like Apple's iPhoto have been doing similar things for a while, Zoe has two innovations: 1) It's completely effortless — the Zoe compilations are automatically generated, appearing as a kind of header to an event (making them even less work than BlackBerry's Storymaker feature). They're created on the fly, so they don't take up any memory, and even though you don't have to, you can customize them to the last detail.
And 2) The camera can take a different kind of photo specifically for Zoes. Instead of snapping a single still, the camera will actually record a short video as well as capture several individual photos. This ostensibly gives the Zoe editor a lot to work with, but the mode doesn't explain itself. I'm certain many users will be confused by Zoe mode when shooting — especially since it's so prominent on the camera's screen.
The Zoe compilations themselves are surprisingly good, somehow keying in on most of the best shots at the toddler party I mentioned earlier. Once I told it to take out one bad video clip and include three can't-miss shots, it was perfect. And it won over more than me: Showing the Zoe to my wife, she insisted I email it to the other parents immediately. Not bad for seven seconds of work.
One complaint: The Gallery app doesn't make it easy to explicitly exclude content from a Zoe — at least short of deleting it outright. A Zoe I compiled of people in the office also had a picture from home in it that I took later that day. The only way I could find to ensure it wasn't included in the Zoe was to designate all 13 pieces of content, so there wasn't room for anything else.
Extra Points
BlinkFeeds and Zoes are nice, but my favorite extra in the HTC One is its ability to serve as your remote control. The power button up top doubles as an infrared blaster, which ties into the TV app. It's called TV and not "Remote" because the app doesn't function solely as a universal remote — it's also a complete channel guide, with graphics and show info.
Setting up the HTC One to control my TV was probably the easiest universal remote setup I've ever performed. After a decade of reviewing remotes, it struck me how much more convenient it is to have the remote control itself connected to the Internet: all instructions, codes and brands were right there on screen — either part of the app or immediately downloaded. Nice.
The remote works very well, and I even appreciated the "content first" approach the the channel guide — where you tap on a particular show that's on, and the TV just knows to tune to it, without ever needing to know the channel. The system mirrors similar apps from Sony and Samsung, so HTC isn't exactly innovating here, but it's following the right trend.
The One also includes NFC (near-field communication) tech, something fairly common in high-end smartphones these days. I wish HTC had put some kind of mark on the exterior to show exactly where the NFC chip is, but after slowly sliding the back of the device over the top of a Sony egg-shaped speaker (model SRS-BT5), I eventually was able to find it. One finger tap later, and I was listening to Pandora at respectable volume. Very nice.
Finally, call quality was excellent. Trying out a Sprint phone made me miss speaking on a CDMA network (my personal phone is on AT&T), and both male and female voices were crisp and clear. The great speakers on the One probably had something to do with it.
How the West Was One
For all its ability to attract friends like Steve Ballmer and Mark Zuckerberg, HTC isn't doing spectacularly well. Its market share and profits lag far behind Samsung's and Apple's, and other Eastern brands such as Huawei and ZTE threaten to undermine the recent progress HTC has made in the West.
With the One, however, HTC has built something it can really stake its future on. The company can't rely solely on brand (like Apple) or momentum (like Samsung), so HTC appears to have correctly reasoned that the only card it can play is quality.
Certainly, some of the things HTC has launched with the One — notably BlinkFeed and Zoe — will need a few iterations to fully blossom, but the fact that they're there at all speaks volumes about HTC's focus. When using the One, you don't feel like the company is just following trends or tossing in a grab bag of features in the hopes that one or two will stand out. Its differentiators are substantive and focused.
For that reason above all else — that the phone has the weight of a company riding on it, with a commitment to the path it's setting out for itself — the HTC One isn't just different from other Android phones out there today. It's better.
Phone images by Nina Frazier, Mashable; screenshots courtesy of HTC; sample photos by Pete Pachal, Mashable


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Ashley Wells, Seth Auberon, Wisdom Quarterly
|Buddha under a fiery Bodhi tree as Mara and yakkhas attack (manicksorcar.com)
Buddhist New Year's celebration with shamans in Far East Russian Buryatia (Sky News)
To meditate or ring in the New Year? Dating a person from Asia, I learned a momentous thing: I was assured that it is a well known and ancient belief that what one does on New Year's Day that is what one will be doing for the year. It makes sense.
There is. Los Angeles has three specific opportunities and an uncounted number of US temples that will be visited tonight and tomorrow morning.
We're always trying to be happy. So we try to be happiest on New Year's eve. But what we think is happy is sometimes nothing more than excess and avoiding. What if there were a way to meditate-in the New Year?
|Bangkok (torchrelay.beijing2008.cn)
SHAMBHALA will hold an open sit from 4:00 pm to midnight. It's not eight hours of straight sitting. There's a celebratory dinner, a video by the "Sakyan" (Chogyam Trungpa Rinpoche's son and heir), walking, and lots of socializing.
AGAINST THE STREAM is following tradition with its New Year's eve "Intention Setting" ceremony. It begins in Santa Monica, ends early, and is repeated in Hollywood on Melrose, which goes into the New Year. There are helicopters, gunfire, fireworks, and a humorous stream of intentions said aloud as candles are lit and Noah Levine gives an encouraging talk.
SELF REALIZATION FELLOWSHIP also holds its annual welcoming the New Year meditation in Glendale in honor of founder Pramahansa Yogananda, Babajii, and the saints of all religions.


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Donald Allen Wilson, long time resident of Ray City, GA, served in the US Air Force in three wars – WWII, Korea, and Vietnam.
LT. COL. (RET. USAF), DONALD ALLEN WILSON, 86, of Ray City died Wednesday, March 26, 2008 at his home. He was born on April 26, 1921 in Rochester, New York to the late Sidney Clinton and Adriene Baldwin Wilson and had lived in this area for many years. Mr. Wilson was a member of the Ray City United Methodist Church and was a 1972 graduate of Valdosta State College. He served in the China Burma India Theatre for eight months and out for one year and then recalled to theatres. Mr. Wilson was a combat pilot in World War II, he flew fifty five night combat missions in Korea in A26's and tour of cargo aircraft in Vietnam. He also did Ford Motor Training.
Survivors include his wife of 65 years, Juanelle Starling Wilson of Ray City, a daughter, Barbara Joyce of Ray City, a son, Dale Allen Wilson of San Diego, Calif., grandchildren, Miriam M. Evans of Tallahassee, Fla., Niccolo Robert Wilson and Sofia Antonia Wilson both of California.
In accordance with Mr. Wilson's request he will be cremated and no formal services will be held at this time. Condolences to the family may be conveyed online at http://www.mclanefuneralservices.com. Carson McLane Funeral Home.


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Prizes and Awards
Every year Stockholm University presents a number of prizes and awards. Stockholm University researchers are also awarded for their achievements by other institutions.
Stockholm University Prizes and Awards
Honorary Doctorates
Stockholm University annually appoints honorary doctors from different fields. An honorary doctorate is an expression of the University's appreciation of outstanding contributions in one or more of the University's areas of academic activity.
Stockholm University Honorary Doctorates
The Award for Good Teaching
Every year the President of Stockholm University awards inspiring university teachers who make outstanding efforts in teaching and pedagogical development. Students and members of staff nominate talented teachers to the award.
The Award for Good Teaching
The Stockholm Prize in Criminology
The Stockholm Prize in Criminology is an international prize, awarded annually since 2006 by Stockholm University, in the field of criminology established under the aegis of the Swedish Ministry of Justice.
The Stockholm Prize in Criminology
Stockholm University researchers awarded by other institutions
Göran Gustafsson Prize
The Göran Gustafsson Foundation for Research in Natural Sciences and Medicine annually gives perennial large grants to researchers in the fields of mathematics, physics, chemistry, molecular biology and medicine in Sweden.
Göran Gustafsson Prize
Nobel Prize
The Nobel Prize, awarded each year since 1901, is internationally the most prestigious scientific prize in the world, given annually to those who have contributed to the greatest benefit to humankind. It is administered by the Nobel Foundation in Stockholm, Sweden. Since 1901, four researchers from Stockholm University have received the Nobel Prize and a fifth has been awarded the Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel. Several Stockholm University researchers are members of the Nobel Committees and take part in the process to decide the next Nobel Laureates. Every year on 8 December the Nobel Lectures are held in Aula Magna at Stockholm University.
Nobel Prize
Wallenberg Academy Fellows
Several of Stockholm University's young researchers are Wallenberg Academy Fellows and as such part of a career programme created by the Knut and Alice Wallenberg Foundation providing long-term funding for young, promising Swedish and foreign researchers from all academic fields.
Wallenberg Academy Fellows
Last updated:
January 28, 2019
Source: External Relations and Communications Office


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Let me start by saying that I really appreciate the fact that Zimbra is FOSS. I also know that it is just the beginning, and that as such it suffers from many compatibility issues.
I am trying to build and install from the CVS version. I am using FC4, on a x86_64 machine. I have encountered some problems while building ThirdParty tools - but I resolved them (I can send the diffs if needed): they mostly invlove adding "-fPIC" to the Native compilation. Once I am done, I will post my experience.
Also, the CVS head is not very stable, and doesn't always compile. Can you please make sure that at least the CVS HEAD branch compiles? I was forced many times to mix-and-match files from vaious dates, just to make the server/client compile ;-)
I use the following guidelines:
* http://www.zimbra.com/blog/archives/2005/08/developing_with.html"
* ZimbraServer/docs/build_cvs_howto.txt
Currently, I have reached the stage where I need to run /opt/zimbra/libexec/zmldapinit. It fails, because of an authentication?? file.
TLS: could not load verify locations (file:`/opt/zimbra/conf/ca/ca.pem',dir:`').
What is this ca.pem file? The "conf/ca" directory is empty in my case - where should have it been initialized?
These are the last lines of running the init script in verbose mode (+slapd in verbose):
daemon_init: ldap://:389/
/opt/zimbra/openldap/etc/openldap/schema/zimbra.schema: line 2832: bad config line (ignored)
bdb_db_init: Initializing BDB database
TLS: could not load verify locations (file:`/opt/zimbra/conf/ca/ca.pem',dir:`').
TLS: error:02001002:system library:fopen:No such file or directory bss_file.c:104
TLS: error:2006D080:BIO routines:BIO_new_file:no such file bss_file.c:107
TLS: error:0B084002:x509 certificate routines:X509_load_cert_crl_file:system lib by_file.c:279
main: TLS init def ctx failed: -1
slapd stopped.
connections_destroy: nothing to destroy.
Started slapd: pid
if [ $? -ne 0 ]; then
exit 1
${zimbra_home}/openldap/bin/ldapmodify -a -c -H ldap://127.0.0.1:389 -w ${ldap_root_password} -D "${zimbra_ldap_userdn}" -x -f ${config_dir}/zimbra.ldif
ldap_bind: Can't contact LDAP server (-1)
if [ $? -ne 0 ]; then
exit 2


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Jason Segel might not have gotten his coveted chance to act alongside Hillary Clinton — but he did get the next best thing: a gracious "declines with regrets" response.
The actor has made no secret of his love for the Secretary of State or his desire to work with her, and he apparently wasn't kidding when he told Jimmy Fallon last week that his would-be co-star had sent him a "rejection letter," Politico reported.
"I was delighted to read about your interest in sharing the big screen with me. As you can imagine, I am a little occupied at the moment, but perhaps someday I can help you forget Sarah Marshall... again," Clinton wrote.
U.S. & World
News from around the country and around the globe
The catch?
"My only condition is that there be Muppets involved, and that is non-negotiable," she added.
Back in March, the "How I Met Your Mother" star had told Us Weekly that he would love to co-star with the Secretary of State.
"I just feel like she would be good at comedy," he said. "I think you can feel it from a mile away."
Bill — and Michelle Williams, for that matter — had better watch out.