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About Authors:
Dhiren Shah*1, Jatin Patel, Krunal Parikh
Seth G.L. Bihani S.D. College of Technical Education, R.U.H.S.
Sri Ganganagar, Rajasthan, INDIA
Abstract :
Involved Evaluation and Standardization techniques for crude drugs, mono or Polyherbal Frormulation. They involved the macroscopic techniques, microscopic techniques, physical evaluation and biological evaluation. They also involved the Quantitative analysis of Organophosphorus insecticides, Organochlorine and pyrethroid insecticides, microbial content determination.
Reference Id: PHARMATUTOR-ART-1506
Evaluation of drug means confirmation of its identity and determination of its quality and purity and detection of nature of adulteration.
IDENTITY: refer to exact authentic biological source of the drug can be established by actual collection of the drug from a plant or animal which has been identified or comparing a representative unknown sample with a published description of the drug with authentic drug sample.
QUALITY: refer to the intrinsic value of drug i.e. the concentration or amount of medicinal principles or active constituents present. These constituents are classified as non-living cell inclusion and have been studied under the heading, the chemical classification. This includes fixed oils, carbohydrates, glycoside, alkaloids, resin, fats or waxes, volatile oil, tannins, vitamins, alergens, etc. A high grade of quality in a drug is of prime importance. An effort should be made to obtain mainly this high quality.
The high grade quality of the drug be accomplished by:
1) Collection of the drug from the correct natural source at proper time and in the proper manner.
2) Preparation of the collected drug by proper cleaning, drying, garbling.
3) Proper preservation of the cleaned, dried pure drug against contamination through moisture, fungi, filth and insects.
PURITY: of the drug depends upon the absence of foreign matters whether organic or inorganic.
The crude drugs can be identified on the basis of their morphological, histological, chemical, physical, and biological studies.
The evaluation of crude drug is necessary because of three reason:
1. Biochemical variation in the drug
2. Deterioration due to treatment and storage
3. Substitution and adulteration, as a result of carelessness, ignorance or fraud
The different techniques involved in standardization of crude drugs are as follows:
· Organoleptic evaluation
· Microscopic evaluation
· Physical evaluation
· Biological evalution
Standardization of herbal drugs is not an easy task as numerous factors influence the bio efficacy and reproducible therapeutic effect. In order to obtain quality oriented herbal products, care should be taken right from the proper identification of plants, season and area of collection and their extraction and purification process and rationalizing the combination in case of polyherbal drugs.
Organoleptic evaluation
Organoleptic (Lit. "Impression on the organs") evaluation of crude drugs refers to the evaluation of a drug by colour, odour, taste, size and shape, occasionally the sound or snap of fracture and special fetures including touch, texture, etc..
Organoleptic evaluation is also called MORHOLOGICAL or MACROSCOPICAL evaluation.
It is a technique of qualitative evaluation based on study of morphological and sensory profiles of whole drugs. Organoleptic evaluation means conclusions drawn from studies resulted due to impression on organ of senses.
PARAMETERS used for this type of evaluation can be explained as follows.
The colour is used in indicating the general origin of drug. e.g. material derived from the aerial part of the plant is usually green and the underground plat material is usually devoid of green colour.
The length, width and thickess of the crude material are of great importance while evaluating a crude drug.
PROCEDURE: A graduated ruler in millimetres is adequate for the measurement of the length, width and thickness of crude maerials small seeds and fruits may be measured by aligning 10 of them on a sheet of calibrated paper, with 1mm spacing b/w lines and dividing the result by 10.
To an expert, odour and taste of crude material are extremely sensitive criteria based on individuals perception. Therefore, he description of this feature may sometime cause some difficulties.
· Indistinct
· Distinct
* Aromatic
* Balsamic
* Spicy
* Fruity
* Mouldy or musty
* Rancid
· Weak
· Strong
PROCEDURE: If the material is expected to be innocuous, place a small portion of the sample in the palm of the hand or a beaker of suitable size, and slowly and repeatedly inhale the air over the material. If no odour is perceptible, crush the sample between the thumb and index finger or between the palms of the hands using gentle pressure. If the material is known to be dangerous, crush by mechanical means and then pure a small quantity of boiling water onto the crushed sample in a beaker. First determine the strebgth of the odour (none, weak, distinct, strong) and then the odour sensation (aromatic, fruity, musty, mouldy, rancid, etc.) A direct comparision of the odour with a defined substance is advisable (e.g. peppermint should have an odour similar t menthol, cloes an odour similar to eugenol)
Tastes are f tw types
· True taste
* Acid (S*ur)
* Saline (Salty)
* Saccharine (Sweet)
* Bitter
* Alkaline
* Metallic
· False taste (Sensati*ns t* the t*ngue)
* Mucilagin*us (s*ft slimy feeling)
* *il (Bland sm**th feeling)
* Astringent (C*ntracti*n *f m*uth tissue)
* Pungent (Warm biting sensati*n)
* Acrid (Unpleasant, Irritating)
* Nause*us (Induce v*miting)
Examine the untreated sample. If necessary, a magnifying lens (6x to 10x) may be used. Wetting with water or reagents, as required, may be necessary to observed the characteristics of a cut surface. The texture is best examined by taking a small quantity of material and rubbing it between the thumb and forefinger, it is usually described as 'smooth', 'rough','guity'. Touch the material to determine if it is soft or hard, bend and rupture it to obtain information on brittleness and the appearance f the fracture plane whether it is fibrous, smooth, rough, granular, etc.
All this characteristics aare valuable in Indicating the general type of material and the presence of more then one component.
For convenience te description of macroscopic characters may be divided into four headings as-
a) Shape and size
b) Colour and external marking
c) Fracture and internal colour
d) Odour and taste
In some official crude drugs monograhs the entire macroscopic description consists of an organoleptic evaluation and is only means of evaluation given macroscopy refers to visual appearance to baked eyes. The macroscopic study depends on the part of the plant from which the drug is obtained.
According to the plant part used all organized drugs can be classified into following groups.
A) Underground plant parts
B) Barks
C) Woods
D) Leaves
E) Flower fruit
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HOUSTON (AP) – When Roger Clemens pitches Saturday night for the Sugar Land Skeeters it will be the first time the 50-year-old has taken the mound in almost five years.
Will he still be the Rocket who intimidated hitters in the majors for more than 20 years? Or will his extended absence and age leave him struggling against players less skilled than the ones he used to face?
Clemens signed with the Skeeters of the independent Atlantic League on Monday and he is expected to start for the minor league team on Saturday at home against Bridgeport.
"His fastball was clocked at 87 mph. All of his pitches were working," said Randy Hendricks, Clemens' agent. "He threw a three-inning simulated game after an extensive workout warmup."
Clemens and Skeeters manager Gary Gaetti have been talking about this "for months," Hendricks said. Clemens is expected to discuss his decision Tuesday during a news conference in Sugar Land, about 20 miles southwest of Houston.
His signing has some wondering if it is the first step in a return to the majors.
Minnesota Twins manager and fellow Texas Longhorn Ron Gardenhire cracked a joke when asked about Clemens on Monday.
"I'll take that Longhorn any day. I don't know all the rules, but I'll be tampering: We do have a spot, right?" Gardenhire said, chuckling.
Clemens, acquitted in June of charges he lied to Congress when he denied using performance-enhancing drugs, hasn't played for a team since pitching for the New York Yankees in 2007 at the age of 45. He went 6-6 in 18 games with a 4.18 ERA that season.
Texas Rangers pitcher Roy Oswalt, a former teammate of Clemens with the Astros, is excited about his friend's return to baseball.
"I think he's going to show everybody that all that stuff that he had to go through had nothing to do with the success he had in the big leagues," Oswalt said. "He said he's going to do it a little bit and see how his body responds. I wouldn't be surprised next year if he's pitching in the big leagues for somebody."
Clemens has been throwing batting practice to one of his sons often, and Oswalt said that Clemens "feels pretty good."
Yankees manager Joe Girardi, who is three years younger than Clemens, said it is difficult to get that urge to compete out of your blood.
"He's always loved to compete," Girardi said of Clemens. "That's who he is. He kept coming back. There were times he felt he couldn't quite go a full season, but he gave it as much as he had. He loved to compete. That's a hard thing to replace is that competition. Guys miss it."
Clemens had two great seasons with the Astros after he turned 40, going 18-4 with a 2.98 ERA in 2004 to win his record seventh Cy Young Award. He was 13-8 with a career-low 1.87 ERA in 2005.
Clemens earned $160 million and won 354 games in a 24-year career with the Red Sox, Blue Jays, Yankees and Astros. His 4,672 strikeouts are third-most and he was named to 11 All-Star games.
Now he will see what he has left for the Skeeters. He joins a roster that includes former major league pitchers Tim Redding and Scott Kazmir and Jason Lane, a teammate of Clemens' on Houston's 2005 World Series team.
"That's great, if he thinks he can do it," Gardenhire said. "He worked harder than anybody I've ever seen. His routine and program, I don't think too many people could stay with that. If he has continued to work out, he's probably in good enough shape. (He's) a big strong Texan."
It isn't clear how long Clemens will pitch for the Skeeters.
"This is a one-game-at-a-time thing," Hendricks said. "Let's see how he does on Saturday."
Some in baseball weren't quite as keen on the idea as Oswalt.
"He didn't travel with the Astros half the time toward the end there," Oakland pitcher Brett Anderson said. "I can't imagine him traveling for the Sugar Land Skeeters. I'm sure they'll draw a good crowd and it will be fun, but it's kind of those things you read about it and you're like: 'What's he doing?'"
Clemens is set to appear on the Hall of Fame ballot going to voters late this year. If he plays in another major league game, his Hall consideration would be pushed back five years.
Clemens was accused of using steroids and HGH in the Mitchell Report on drugs in baseball, something he denied. The Justice Department began an investigation concerning whether Clemens had lied under oath, and in 2010 a grand jury indicted him on two counts of perjury, three counts of making false statements and one count of obstructing Congress when he testified during a deposition and at a hearing that he never used any performance-enhancing drugs.
He was acquitted of all the charges on June 19 after a 10-week trial and has largely stayed out of the public spotlight until now.
"I think he's going to come back and try to prove a lot of doubters wrong," Oswalt said.
The signing was first reported by Houston television station KRIV.
(© Copyright 2012 The Associated Press. All Rights Reserved. This material may not be published, broadcast, rewritten or redistributed.)
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Territorial A-ZA | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 0-9
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Authors: Congregational Church of Mount Gilead
Date: April 2, 1859
This small note/ledger volume contained some "Records of the Congregational Church of Mt. Gilead Anderson Co Kansas Territory," which may have been recorded by John S. Hanway, the son of James Hanway (but John S. Hanway's name is not given among members, etc.). The volume covered about a year and a half, from the church's inception in April 1859 to the last dated entry in September, 1860, and was composed mainly of the congregation's articles of faith and by laws. Samuel L. Adair led devotions at the first meeting. The church's first members and/or officers were Wakeman and Mary E. Partridge, J. F. and Ruth I. Wadsworth, Lydia Gilpatrick, Margaret Potter, and William Loomis.
Keywords: Adair, Samuel Lyle; Anderson County, Kansas Territory; Articles of faith; Churches; Congregational Church of Mount Gilead (Anderson County, Kansas Territory); Congregational churches; Gilpatrick, Lydia; Hanway, James; Hanway, John S.; Loomis,William; Mount Gilead, Kansas Territory; Partridge, Mary E.; Partridge, Wakeman; Polter, Margaret; Wadsworth, J. F.; Wadsworth, Ruth I.


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Some truths manage to brand themselves within the inner sanctums of the human mental condition.
Yet these same truths also have their deniers. We would like to deny those particular truths because they are the recurring nightmares of history. The truth is real, but we some how hope… Are there not exceptions to the everyday, sacred laws of existence?
One such historical truth concerns the evils of the State and its sordid Political-Economy. In Ancient History, there were some exceptions to that Historical Rule of Barbarity – but within our Modern-Contemporary world, the exceptions have all but disappeared. The cruel actuality of our existence has exposed the Truth's putrid venom.
At one time in the Sahel of West Africa, whipped the brush, and scented-blinding winds of imperial glory – which also included tribute taxations, violent conquests, extensive householder slavery, and a wealth in bullion where the prosperous Islamic merchants of Baghdad would even bow their knees in glory.
The decade was the 1230's AD. The great Pagan Empire of Ghana was losing its power to the glorious Muslim armies of the Almoravid Empire, which had already reconquered Spain, Andalus, for Dar-Al Islam. A vision came upon the political leaders of the Malinke Nation concerning a new imperial creation. The leader of destiny was Sundiata Keita.
He established a disciplined army of strong Malinke soldiers who allied with other tribute nation warriors. This great army had marched onward to war. Through his tactics and discipline, he won both the battles – and the final war.
Malinke then established an even greater Empire in the Sahel, from the semi-deserts of North Africa, all the way to the tropical forests of West Africa, later called Mali.
Many Empires have decayed after their first conquests, since the ancient warrior-leaders often neglected their original successions and recent conquests. But not this Empire – as the years passed, the Mali Empire seemed to expand and increase into even greater political distinction.
The Empire ruled over the river commodity exchanges of the Niger and the Wangara. The Mali Kingdom received massive tributes in gold, human slaves, tributary soldiers and salt.
This Empire understood that a successful ancient empire must tax human migrations, labor, armies, hard currency and spice-foodstuffs, all in order to control the surrounding cultures. This empire controlled so much land that only the Mongols in the northeast had conquered more territories. Soon, Europe, Africa and Asia heard of the fantastic stories concerning its wealth and massive army.
The emperors, or Mansas, like the Mongols later in history, converted to the religion of Islam. But this was not a strict regimen. A type of syncretic religious system developed where West African rituals and native myths mixed with Islamic world culture, all of which fused into a new cosmopolitan civilization, headquartered in the magical city of Timbuktu. Timbuktu would later possess a massive university system for Islamic scholars and intellectuals.
A hundred years later, the great Mansa Musa took the throne, and he decided to perform a great pilgrimage to Mecca. He would travel with his elite soldiers, harem entourage, slaves, exquisite food – and his gold, through the Sahel and the Sahara. This pilgrimage of power and piety had thus become Historical Legend.
All the senses exploded upon urban Islamic civilization. Mansa Musa ate sumptuous meals flavored with the exotic herbs and spices of West Africa. His servant slaves were armed and had powers too. They acted more like family then humiliated peons. All of his entourage, including his slaves, wore fine clothes of leisure and sensuality. Their deep colors represented the magical Earth of orange-blue African sky, and the dry Sahel yellow ochre-green savannahs salad, mixed with tropical green-brown, pasta strewn forests. Their weapons of war seemed like works of art – even though they could maim and kill with gentle ease. But it was the overall, carefree existence of that royal entourage, in truly holding such wealth, yet not boasting of it, nor showing it off.
Musa gave generously to all religious institutions on his spiritual path, while the merchants of the great Islamic cities stood in the awe at the generosity and nobility of such an emperor. Mansa transformed into a type of mystical Sun King bursting upon the Earth from the Heavenly Golden Palace.
At that same time in history, the Europeans were suffering from the horrible effects of the Bubonic Plague, which had already killed a third of its population. They failed to see their own dirtiness and hypocrisy, and so they looked in askance. Those dirty Europeans would return to Africa with a vengeance however.
But like always in the sordid annals of human history, the cusp of imperial greatness also leads to the slow and painful decline and fall – to eventual extinction. Another one hundred and thirty years later, one of Mali's tributary states had successfully revolted and conquered Timbuktu.
This empire was the Islamic West African Kingdom of Songhai. The Songhai supported the intellectual life of the university at Timbuktu however, while they had succeeded in capturing the tributary taxes of the previous Malian rulers.
Unfortunately, the Malians tried to enlist the devious Europeans in their desire for continued power and glory. They chose the Portuguese maritime seafarers in order to further their reconquest. This became a terrible omen, for it was the Portuguese maritime empire that first established the mass murder system of the African Slave Trade in the mid 1400s.
Meanwhile, other African nations wanted greatness for their own kingdoms, such as the Wolof, the Hausa, the Benin and Ashanti. To the east, existed the Muslim African Empire of Kanem-Bornu. The Europeans discreetly understood the devious applications of Divide and Conquer.
This imperial history of West Africa perfectly explains the nature of the Ancient State. West African Kingdoms sought their power bases through family dynasties, tribute taxations, a political economy of patron slavery, and a warfare-conquest spoils system.
Most of the subject people were farmers and artisans. The wars rarely touched them. One Empire came, and then another dynastic authority took its place. And such was the bittersweet cycle of life. The new King shone bright, only to die unto History's dust.
The Ancient state and political-economic systems of tribute tax-paternalism were not necessarily brutal. Even Alexander the Great did not willfully murder whole populations of cities, nor did he target entire ethnic-religious groups for mass extermination.
The Judeo-Christian Monotheists, i.e. the Israelites of Numbers, Deuteronomy and Joshua, and the Medieval Christian Crusaders were the first ancient mass murderers or paleo-Nazis.
Yet, the ancient stories of the West African Empires fully explain the modus operandi of the State and its political-economy, always based on the power of one group over another.
Power is simply the legal rights to use violent methods for whatever reasons found necessary, which include intellectual and economic forms over subject populations. As the modern intellectual Max Weber wrote, the State always holds the final means for a total monopoly of violence. Or as we Anarchists proclaim: the most dangerous, violent criminals are State actors and their economic elites.
Yet the modern state has transformed into a wholly different, and much deadlier, rabid animal-monster. When Capitalism and its brutal profit motives invaded the daily life of humanity, during the 19th century; something in the State Sadist changed drastically – and for the worse.
A perfect historical example that exposes the criminality of the modern State is the so-called Risorgimento, or the forced unification of the Italian States during the 1860s.
The 1860s represented another violent decade across the human globe. In Japan the Emperor Meiji successfully destroyed the Tokugawa Shogunates and the Daimyo gangs ruling over the Japanese populace. The Second German Reich birthed through continual wars against its weaker neighbors: Denmark, Austria and France. The British Empire invaded and subdued the Bhutanese in South Asia. The Russian Emperor eliminated the Serfdom system, while the American Empire invaded, subdued and committed atrocities against the white South, or the Confederacy, while liberating the African-American slaves – yet giving them nothing to live on! The French Empire invaded and subdued Mexico, while three Latin American countries: Brazil, Argentina and Uruguay joined together in a War of Extermination against the Paraguay Nation.
But there was one invasion that most historians completely forgot during that same historical period. A royal-aristocratic gang of social parasites, using a bunch of Liberals as the public face of the movement, invaded another royal-aristo stronghold, and then murdered a substantial part of the rural population who had refused to give allegiance to the new bosses.
The royal house of Savoy, who spoke better French than Italian, allied with another local aristo, named Count Cavour, all of whom were located in a region of northern Italy, called Piemonte-Saboya. Those crooks came up with an ingenious plan to continue their corrupt political rule. They surfed on the Euro-Nationalist wave, and later transformed their juntas of soldier-thugs into the Italian National Army.
Those men were not stupid. In order to give a noble veneer to their wicked deeds, they publicly used Italian Nationalist-Liberals for the public face of the movement. They chose two notable Liberals: Giuseppe Mazzini who represented the political wing, and Giuseppe Garibaldi who represented the military wing.
No war is complete without a violent invasion, and so this ugly cabal from the north of Italy attacked another degenerate royal-aristo base in the southern part of the country, ruled by the Spanish Bourbon parasites, called the Kingdom of the Two Sicilies.
This was not just a fight between two different Euro-parasites for the control of a new country. The Piedmont-National Army also conducted mass murder across the rural country of southern Italy in order to fully subdue any resistance to the new kings. This Northern Army murdered around 100,000 southern Italians. This early counterinsurgency program worked quite splendidly, and so, the new National government in Rome annexed the southern peninsula. But war always leaves its scars of loss, anger, hunger and poverty.
Whole regions in the South lost valuable men and the almost self-sufficient farmers lost portions of their lands. The National Government allied itself with the local Southern aristos, carpetbagger politician-elites from the north, and the Camorra-Mafia gangs – to fully control the wealth of the region.
The Great Italian Emigration began from the South to the North of the country, to northern Europe, and across the globe, mostly to the Rio de Plata of South America and to the United States, in order to look for work. Still to this day, in Modern Italy, the North and Rome accuse the Southerners of weakening Italy's greatness.
This is what the modern state and its economic elites do to modern peoples. Unlike the ancient states, they don't just invade, amass two armies for battle, scale the walls, and then retake the palace, they also commit mass murder exterminations against civilian populations, or an act of total war against a subject population.
Why do they do this? Because our Modern Lives have lots of non-State media sources: printed publications, theaters and public spectacles. The Modern State demands that all subjects not just respect it, like a good gang leader – but also fear its criminal power of destruction. Fear works even better for the complete social control of subject populations.
The Modern State with its full monopoly of violence and legal crime always demands the center stage, the center of national attention. The National Official History is the history of its own appropriated, great leaders. National Culture is its own appropriated lies and state propaganda babble, often relayed through boring, school-university textbooks.
Do any of us still believe that a mass murderer-serial rapist will somehow transform himself or herself, and suddenly become a nice and respectful person? So then why do we continue to believe such criminal institutions, the State and their economic elite enablers, will all of a sudden reform themselves and reject the monopoly of violence.
Let all attentive subjects awake to the ides of History.


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I have a ubuntu samba server on my network and almost 70% of the office employee uses it everyday. It is not secured (free public shares) and anyone on my network can access it. As the office is expanding i need to secure it.
Is it possible to trace the user's history? Something like i can view the file he dumped, copied, or deleted. From what computer he logged in to use the file sharing server.


text: Aston Martin Racing News Tags AMOC Awards Brand Extension Centenary Corporate Dealers Events Films Gaydon GTE Heritage le mans Licensees Models Motor Shows Nürburgring Partnerships People Promotion Q by Aston Martin Racing Social Media Videos ASTON MARTIN CONTINUES STRONG DISPLAY AT NÜRBURGRING 24H AT EIGHT HOUR MARK Published: Jun 21, 2014 Tags: Nürburgring, Racing by Pete Norwood Midnight marks the eighth hour of racing at the 2014 Nürburgring 24 Hours and the #007 Vantage GT3 is back inside the top ten of the 169-strong grid. Nürburgring, 22 June 2014 - Midnight marks the eighth hour of racing at the 2014 Nürburgring 24 Hours and the #007 Vantage GT3 is back inside the top ten of the 169-strong grid. Two of the Aston Martin entries continue to hold podium placed positions - the #100 V8 Vantage N430 second in SP10 and #55 V12 Vantage third in SP8. With the past four hours seeing competitive lap times delivered by both Stefan Mücke (DE) and Darren Turner (GB), the #007 Vantage GT3 is currently occupied by Pedro Lamy (PT) in eighth position. Darren Turner said after exiting the car, "On the track we're performing very well. I had a few sectors of the track which were clear and I was able to push hard and really enjoy my time in the car. It's times like these where you experience the real highs of being a racing driver and also the fear of god." The #100 V8 Vantage N430 continues its impressive performance, with both British journalists Dickie Meaden and Chris Harris enjoying successful sessions, ensuring the car remains in second place in SP10. At the eight hour mark, Nürburgring specialist Andy Gülden (DE) remains in the car on the second of his back-to-back stints. "I was supposed to get in the car about half an hour ago but Andreas is doing a great job hunting down the leader and is feeling good so he stayed out," commented Dickie Meaden (GB). "We're now within 30-seconds of the front of the class." The #55 V12 Vantage currently sits third in SP8 while the second V8 Vantage N430, car #70, is fourth in SP8. Back to all news items Share Facebook Twitter Google Plus Linked In Downloads Languages This article is available in the following languages: - English Cars Teams Series Partners History News Contact


text: atrypa Member Posts: 1 (2/16/02 5:21:13 pm) Reply | Edit | Del All Goff 1802 Flintlock -------------------------------------------------------------------------------- Help, please. My friend just inherited a pistol. We searched the Internet and couldn't find out anything about it specifically. But. We did find an identical pistol with the same exact markings. Same metal marks, same walnut, same brass, etc. The pistol is described as a 'Nock East India Company Pattern Dragoon Flintlock'...the #1802 (the year?) is prominent. Her gun is the exact same except where it say 'Nock', the pistol says 'Goff'. Why identical guns but different names? Could someone please direct us to a website to identify this gun and learn more about it. We assume, maybe wrongly, that Goff and Nock were gunsmiths? Also, a long knife was left also. The metal, etc. matches the pistol. There are 2 interchangeable blades. Could they have been issued with the pistol? The gun was fired once each year on Victoria Day, but neither of us have fired a gun before so we would like to just get info on the gun instead. Special help, please. Could this message be transferred to the right forum if this is not it. We are not sure of the meanings of some ogf the headings. warpig883 *TFF Staff* Posts: 2452 (2/16/02 5:33:45 pm) Reply | Edit | Del Re: Goff 1802 Flintlock -------------------------------------------------------------------------------- atrypa Welcome to The Firearms Forum. This is not quite the right place to ask your question but it is 6 of 1 - 1/2 dozen of the other so we should just leave it here. I looked around some and cannot find anything on your pistol but my resources are very limited and my knowledge of such things needs improvement. There should be a bunch of people through here in a little bit who might be able to help you. Stick around and learn something or just tell us a story or two We can't be so fixated on our desire to preserve the rights of ordinary Americans... -- Bill Clinton, US President (USA Today, 11 Mar 1993, page 2a) Tac401 Administrator Posts: 3613 (2/16/02 5:40:21 pm) Reply | Edit | Del ezSupporter Re: Goff 1802 Flintlock -------------------------------------------------------------------------------- atrypa, Welcome, you may want to post this in our "What's It Worth / Ask The Pro's" forum also. One of our experts will be along shortly to help you out. The Firearms Forum Vietnam Memories Bulletin Board Contact Administrator AntiqueDr *TFF Senior Staff* Posts: 2049 (2/16/02 6:06:16 pm) Reply | Edit | Del ezSupporter Re: Goff 1802 Flintlock -------------------------------------------------------------------------------- Nah, leave it here. The reason the guns are so similar (I would hesitate to call them identical since both are largely hand-made) is because they were contracted to a specific pattern. Goff and Nock were both major gunmakers of the period, and filled contracts for military-type pieces for various entities in the British Empire. The East India Co was the largest foreign-trade operation in the world at that time, as Britain was expanding its colonization of the globe. Nock was especially noted for a special "screwless" lock, but I doubt it was fitted to these pistols. By the way, this type of pistol is more popular called an "East India Co pistol" or a "light-cavalry pistol," depending on the collector. They are more often seen and sold in the UK than in North America (you're in Canada, right?). Recent auctions have turned $900-$1000 US for decent examples with similar dates, by Goff. We Buy Guns! 1 - 100, Antique or Modern! www.apaxenterprises.com Xracer *TFF Senior Staff* Posts: 1665 (2/16/02 7:07:39 pm) Reply | Edit | Del Re: Goff 1802 Flintlock -------------------------------------------------------------------------------- Hi atrypa, and welcome to TFF! polishshooter *TFF Senior Staff* Posts: 2885 (2/17/02 6:24:28 pm) Reply | Edit | Del Re: Goff 1802 Flintlock -------------------------------------------------------------------------------- Yeah, welcome! Until about the Hall rifles circa 1812 or so, just about EVERY gun was a handmade "one-of...," and even for a long time afterwards too... And many are made like Doc said to a same general "pattern," but by different gunmakers, sometimes 5-3000 miles apart. Collecting original flint or percussion rifles, pistols and muskets is it's own industry, there ARE many fakes out there, and since there many times isn't a whole series of firearms to compare, like later, it can be tough to spot, which will affect the value of that firearm or ones like it, or at least the question of it, every time it changes hands. What I would do is try to get as much of the ownership history of the firearms down on paper NOW, and get previous owners to sign in affidavit form, and keep the papers with the firearm. Firearms last relatively forever, we are merely "temporary owners" ot "caretakers" of them, and 100 years from now it will belong to someone, either through inheritance, or sale, or both, that will probably know less about firearms in general, or this one specifically than you or we know now, so you will be doing everyone down the road a big favor to preserve not only the gun, but what history of it you can. This is for all other historical pieces too, but is more important for these pre-mass production guns, because for those we do have pretty good documentation, whether from the factory, dealers, or actual users. We must make war as we must; not as we would like. - Field Marshal Kitchener, 1915 atrypa Member Posts: 2 (2/18/02 4:45:25 pm) Reply | Edit | Del Thanks -------------------------------------------------------------------------------- Thank you for the wonderful information. This gun has been in my friend's family for almost 200 years. We told her Grandma the info and she let us open one of the wooden crates in the root cellar. We were hoping to find more guns but instead found a lot of strange metal objects covered with old cloth and what might be grease. Maybe some of the other crates have guns. Her Gram thinks the crates were put there for storage when we fought the Americans in 1812 but that we won the war before the weapons had to be used. She doesn't know why she thinks this but it somehow is just known in the family. We think her grandfather's pistol and knives were from one of the crates but there are no documents. polishshooter *TFF Senior Staff* Posts: 2903 (2/18/02 9:26:03 pm) Reply | Edit | Del Re: Thanks -------------------------------------------------------------------------------- WOW, what a find... I meant the crates, also, not just the different perspective on just who "won" the War of 1812... YES, the US invasion of Canada went over like a lead balloon...(but we gave the Brits a bloody nose at Lundy's Lane, just MIGHT have won if the darn New York militia would have VOTED to cross the Niagara and FIGHT instead of staying on the other side and WATCHING! ( ) But then again, maybe if you WOULD HAVE revolted then and joined us AGAINST the Brits like we thought you would at the time we invaded, you'd have "sane" gun laws, quality health care, survivable taxes, and a dollar worth more than $.65... The war was NOT between the US and Canada, but the US and ENGLAND...and at best it was a draw...at least until we kicked Pelhams butt at New Orleans, but then the war was already over for 3 months so it didn't count... Just a friendly neighborly formerly Bradour drinking joke there...(for the most part... ) I LOVE Canada, spent alot of time there, and should the Liberals ever succeed in taking over down here, I just might like to live there instead someday, if you are going to be miserable and oppressed, you might as well do it with Molson and Mist... (unless I can "hide" in Alaska....) I love International Welcomes! AND BTW, just maybe you should check with the OPP before you start showing it around, knowing Canadian gun laws, you are probably ALREADY a felon for just the "possession..." We must make war as we must; not as we would like. - Field Marshal Kitchener, 1915 Edited by: polishshooter at: 2/18/02 9:28:49 pm Bob In St Louis *TFF Senior Staff* Posts: 1866 (2/18/02 9:43:17 pm) Reply | Edit | Del Re: Thanks -------------------------------------------------------------------------------- "strange metal objects"? Interesting. Sounds like they are wrapped in oil cloth. Are the objects flat, blade like, or maybe conical or cylindrical? I sure hope you don't have crates of old Parrot shells or mortar rounds ---- Crusty Cruffler of Fine Spanish Pistols - Eibar Rules! warpig883 *TFF Staff* Posts: 2491 (2/19/02 10:00:11 am) Reply | Edit | Del Re: Thanks -------------------------------------------------------------------------------- I also would love to hear more about the contents of the mystery crates We can't be so fixated on our desire to preserve the rights of ordinary Americans... -- Bill Clinton, US President (USA Today, 11 Mar 1993, page 2a) gun runner john *TFF Staff* Posts: 463 (2/19/02 11:06:53 am) Reply | Edit | Del Re: Thanks -------------------------------------------------------------------------------- I'd be careful not to blow yourself up determining the contents of those old crates! atrypa Member Posts: 3 (2/19/02 12:20:35 pm) Reply | Edit | Del Thanks -------------------------------------------------------------------------------- I don't think the crates could blow up. We did some research and back then the bullets didn't have gunpowder in them. We now think the metal things are tools . We surfed the Web and some look like the ones used for shaping the metal to make bullets. The gunpowder was put in the barrel after the bullet was put in. Gunpowder was probably stored separate back then so they could be rolled off ships if there was a fire. A good book on the War of 1812 is the one by Pierre Berton. He is Canada's most famous historian and we read a couple of his books in school. The Americans were forced back everywhere and failed in their conquest. Canada has never been in a war that we lost. The Americans have lost only 2, the War of 1812 and the Vietnam War, but I don't think you have to worry about losing another one in the next 100 years. Bob In St Louis *TFF Senior Staff* Posts: 1873 (2/19/02 9:20:51 pm) Reply | Edit | Del Re: Thanks -------------------------------------------------------------------------------- Bullets were not cased and charged, but mortars and parrot shells had blackpowder charges in them. The bullet molds, strickers, ladels, etc., if that is what you have, are worth a pretty penny on the antique market too. Crusty Cruffler of Fine Spanish Pistols - Eibar Rules! polishshooter *TFF Senior Staff* Posts: 2927 (2/25/02 7:10:50 pm) Reply | Edit | Del Re: Thanks -------------------------------------------------------------------------------- I repeat, America and Canada have NEVER fought a war... The War of 1812 was between the US and Great Britain over a lot of issues NOT involving the then British owned Canada...and Great Britain LOST on all if not most of them.... The British DID push us back in our ill concieved and poorly supported quest to "Liberate" the Canadians...who decided they LIKED the oppression... But the "Invasion of Canada" was almost an Ad-Hoc "afterthought," not even a stated reason for the war. "It seemed like a good idea at the time," since we were at war ANYWAY. It wasn't even a main campaign theater for us, no matter what "your" history books say, sorry...if more of your anscestors would have supported and joined us instead of supported the crown, your books WOULD have been written differently... And it WAS a close thing, we almost pulled it off with a few soldiers and almost no logistics... But since we DID get most of what we went to war for, and gave the Brits a few bloody noses, in exchange for allowing them to burn DC a little (not enough, in some opinions... ) I'd have to say by any reckoning, 1812 was a US Victory....granted, NOT a resounding one... And as time goes on, even Vietnam is starting to look more and more like a "win" too... But, if the stuff in the crates are molds, go over them carefully, and see if you have one that matches the handgun. Machining was not precise back then, and each bore had a specific mold made at the same time, to fit the unique bore...if you HAVE one to make a set, the pistol is worth alot more... Bob, Canada never had Parrots or the like, with bagged charges, in fact, I don't know if they would have had any arty after the revolutionary era stuff, until WWI or so, and even that was mostly British stuff issued overseas...most arty pre-1812 loaded loose powder with a sort of scoop before the wadded shot was seated.... But there COULD be powder in there, be careful, that stuff gets unstable with age...don't smoke obviously around it, but also, be careful with sparks or static electricity.... A tiger never changes his spots.


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Your data, powering your experiences, controlled by you.
Satya Nadella
At Microsoft, our mission is to empower every person and every organization on the planet to achieve more. We are doing this by building an intelligent cloud, reinventing productivity and business processes and making computing more personal. In all of this, we will maintain the timeless value of privacy and preserve the ability for you to control your data.
This starts with making sure you get meaningful choices about how and why data is collected and used, and ensuring that you have the information you need to make the choices that are right for you across our products and services.
We are working to earn your trust every day by focusing on six key privacy principles:
These principles form the foundation of Microsoft's approach to privacy and will continue to shape the way we build our products and services. For enterprise and business customers, check out the Microsoft Trust Center to find out how we protect your data in the Microsoft Cloud.
On the rest of this website, you'll find links to more information and controls so you can make the right decisions for you. And we're constantly working to improve, so if you notice something in our products and services that doesn't work the way you'd expect when it comes to privacy, please let us know.
Microsoft collects data to help you do more. To do this, we use the data we collect to operate and improve our software, services, and devices, provide you with personalized experiences and to help keep you safe. These are some of the most common categories of data we collect.
Like many search engines, we use your search history, and the history aggregated from other people, to give you better search results. To speed up web browsing, Microsoft web browsers can collect and use browsing history to predict where you want to go. Cortana can make personalized recommendations based on your browsing and search history.
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John Glenn will sell all sport and season passes from 8 a.m. to 3 p.m. starting Monday in the high school office.
All sport passes for adults cost $75 and students $50, football season passes are $25 for adults and $15 for students and soccer season passes for boys and girls games are $30 for adults and $15 for students.
Gold Card for all residents 65 or older who live in the East Muskingum School District provide free admission to all fall sports. Passes must be picked up at the high school and are good for all athletic events held in East Muskingum Schools.


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Cabazitaxel Plus Prednisone With Octreotide For Castration-Resistant Prostate Cancer (CRPC) Previously Treated With Docetaxel
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01469338
Recruitment Status : Terminated (lack of funding)
First Posted : November 10, 2011
Last Update Posted : November 24, 2014
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Diarrhea Hormone-resistant Prostate Cancer Recurrent Prostate Cancer Stage I Prostate Cancer Stage IIA Prostate Cancer Stage IIB Prostate Cancer Stage III Prostate Cancer Stage IV Prostate Cancer
|Drug: cabazitaxel Drug: prednisone Drug: octreotide pamoate Other: questionnaire administration Drug: octreotide acetate
|Phase 2
I. To evaluate the impact of octreotide in reducing the incidence of grade 2 or greater diarrhea in men receiving cabazitaxel plus prednisone for castration-resistant prostate cancer (CRPC) after docetaxel therapy.
I. Overall survival (OS).
II. Progression-free survival (PFS) (defined as the time between treatment start and the first date of progression as measured by objective tumor progression using the Response Evaluation Criteria In Solid Tumors (RECIST), pain progression or death).
III. Prostate-specific antigen (PSA) response rate.
IV. Objective response rate.
V. Pain response.
VI. Toxicity.
Patients receive cabazitaxel as intravenous (IV) infusion over 1 hour on day 1, prednisone by mouth (PO) every day (QD), and octreotide pamoate given as intramuscular (IM) injection on day 1. Patients also receive octreotide acetate as a subcutaneous (SC) injection three times a day (TID) on days 1-14 of course 1 only. Treatment with cabazitaxel repeats every 21 days and treatment with prednisone and octreotide pamoate repeats every 4 weeks for up to 10 courses in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up at 1 month, every 3 months until disease progression, and then every 6 months thereafter.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|9 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Supportive Care
|Official Title:
|A Phase II Clinical Trial of Cabazitaxel Plus Prednisone With Octreotide in the Treatment of Castration-Resistant Prostate Cancer (CRPC) Previously Treated With Docetaxel
|Study Start Date :
|July 2012
|Actual Primary Completion Date :
|October 2014
|Actual Study Completion Date :
|November 2014
Experimental: Supportive care (management of therapy complications)
Patients receive cabazitaxel IV over 1 hour on day 1, prednisone PO QD, and octreotide pamoate IM on day 1. Patients also receive octreotide acetate SC TID on days 1-14 of course 1 only. Treatment with cabazitaxel repeats every 21 days and treatment with prednisone and octreotide pamoate repeats every 4 weeks for up to 10 courses in the absence of disease progression or unacceptable toxicity.
Drug: cabazitaxel
Given IV
Other Names:
Drug: prednisone
Given PO
Other Names:
Drug: octreotide pamoate
Given IM
Other Names:
Other: questionnaire administration
Ancillary studies
Drug: octreotide acetate
Given SC
Other Names:
- Development of Grade 2 plus diarrhea [ Time Frame: Baseline through 21 days after the last administration of cabazitaxel ]Defined by Common Terminology Criteria for Adverse Events (CTCAE) v4.0 criteria as an increase in frequency of 4 or greater stools per day over baseline, incontinence, diarrhea warranting hospitalization or diarrhea limiting self-care activities of daily living (ADL). Baseline frequency will be defined in the pre-treatment assessment from cycle 1 as the maximum number of stools in one 24 hour period during the past 2 weeks. Any incidence of grade 2 or greater diarrhea during treatment or for up to 21 days after the last administration of cabazitaxel will be included in this endpoint.
- Progression-Free Survival [ Time Frame: At 1 month after completion of treatment, every 3 months until disease progression, and then every 6 months thereafter ]
- Overall Survival [ Time Frame: At 1 month after completion of treatment, every 3 months until disease progression, and then every 6 months thereafter ]
- RECIST response for patients with measurable disease [ Time Frame: Baseline, after every 4 courses, at the end of treatment, and then every 6 months ]
- Prostate-Specific Antigen response [ Time Frame: Baseline, day 1 of each course, at the end of treatment, and then every 6 months ]
- Pain palliation in patients with a baseline pain score greater or equal to 2 [ Time Frame: Baseline, day 1 of each 3 week course, at the end of treatment, and then every 6 months for up to 52 weeks ]
- Toxicity (adverse events considered to be at least possibly drug-related) [ Time Frame: Baseline, day 1 of each course, and at the end of treatment ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Histologically or cytologically confirmed prostate cancer
- Measurable disease on computed tomography (CT) or evaluable disease with an elevated PSA
- Documented progression on (a) at least one prior hormone treatment, which must have incorporated luteinizing hormone-releasing hormone (LHRH) agonist therapy AND (b) at least one chemotherapy regimen, which must have included docetaxel; progression may be demonstrated by radiologic criteria or by PSA only if accompanied by new or worsening symptoms (pain progression)
- Eastern Cooperative Oncology Group (ECOG) performance score of 0-2
- Absolute neutrophil count (ANC) more than or equal to 1500/ul
- Hemoglobin more than or equal to 8.0 g/dL
- Platelet count more than or equal to 100,000/ul
- Serum creatinine less than or equal to 1.5x the upper limit of normal (ULN)
- Bilirubin less than or equal to ULN
- Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) less than or equal to 1.5x ULN
- Must be recovered from acute and late effects of any prior surgery, radiotherapy or other anti-neoplastic therapy
- Patients or their legal representatives must be able to read, understand, and provide informed consent
- Men of childbearing potential must consent to use barrier contraception while on treatment and for 90 days thereafter
- Palliative radiation for metastatic disease is allowed if less or equal to 40% of the total bone marrow was irradiated; 28 days must have elapsed since completion of radiation therapy (RT) with bone marrow recovery; soft tissue disease irradiated in the prior 2 months may not be designated as measurable disease
- Concomitant bisphosphonate use is permitted if the dose had been stable for 12 weeks prior to enrollment
Exclusion Criteria:
- Treatment with radiotherapy, chemotherapy or any investigational agent in the prior 4 weeks
- Major surgery in the prior 4 weeks
- Prior treatment with cabazitaxel
- Patients with known hypersensitivity to cabazitaxel, other drugs formulated with polysorbate 80 or octreotide
- Inability to tolerate oral prednisone
- Grade 2 or greater diarrhea in the prior 2 weeks
- Grade 2 or greater neuropathy or stomatitis
- Presence of an active uncontrolled infection or fever greater or equal to 38.5 degrees
- Presence of parenchymal brain metastases; patients with neurological symptoms must have a CT or magnetic resonance imaging (MRI) of the brain showing no metastases within 60 days of enrollment
- Prior malignancy within the past 5 years with the exception of curatively treated basal cell or squamous cell carcinoma of the skin or superficial bladder or other stage I or stage II cancer in complete remission for at least 12 months
- History of unstable or newly diagnosed angina pectoris, documented history of current serious arrhythmia or congestive heart failure (CHF) or recent myocardial infarction (MI)within 6 months of enrollment
- Known human immunodeficiency virus (HIV) or hepatitis infection
- Life expectancy less than 3 months
- Presence of any other medical condition, including mental illness or substance abuse, deemed by the investigator to be likely to interfere with a patient's ability to sign informed consent, cooperate and participate in the study, or interfere with interpretation of the results
- Lack of ability/willingness to give informed consent
- Lack of ability/willingness to receive octreotide injection
- Anticipated non-availability for study visits/procedures
- Patients with uncontrolled diabetes, defined as a HbA1c greater than 7% or greater or equal to 8% despite therapy, or a fasting plasma glucose more than 2x ULN; at the investigator's discretion, non-eligible patients can be re-screened after adequate medical therapy has been instituted
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01469338
|United States, California
|USC/Norris Comprehensive Cancer Center
|Los Angeles, California, United States, 90033
|Principal Investigator:
|Jacek Pinski
|University of Southern California
|Responsible Party:
|University of Southern California
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
NCI-2011-03266 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
|First Posted:
|November 10, 2011 Key Record Dates
|Last Update Posted:
|November 24, 2014
|Last Verified:
|November 2014
Prostatic Neoplasms
Genital Neoplasms, Male
Urogenital Neoplasms
Neoplasms by Site
Prostatic Diseases
Signs and Symptoms, Digestive
Anti-Inflammatory Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Antineoplastic Agents, Hormonal
Antineoplastic Agents
Gastrointestinal Agents


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ll Us for Safe Toronto Squirrel Removal
360 Wildlife Control provides safe, humane squirrel removal in Toronto. With our knowledgeable and experienced team we are the go to company when it comes to dealing with wild squirrels. We understand their nesting habits and seasonal behavior. We use this to help us execute our services without harming the squirrels involved. We are here to provide you with the most cost effective and efficient methods possible.
Where Do Squirrels Typilly Nest?
When squirrels are in search of a nesting area, they tend to look for high, warm places. If that isn't possible they will resort to building their nest in an attic. They do this by chewing a hole in your roof and entering from there. This n use major damaged to the exterior and interior of your home. 360 Wildlife is your best Toronto squirrel removal company serving the GTA.
What Threats Do Nesting Squirrels Pose?
- Squirrels are notorious for chewing through wood, plastic and aluminum. This puts your property at risk of major damage.
- When squirrels are able to enter your home, they then n chew wires and insulation.
- Pets and small children are at risk if a mother squirrel feels threatened or if her babies are in harms way.
- Squirrels droppings n spread diseases and if not removed these diseases n pose a health to humans.
Guaranteed Humane Toronto Squirrel Removal Services
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How Are Squirrels Removed?
Through our experiences we have created a variety of safe removal methods for squirrels. The most used strategy incorporates using a one-way door system. To start off we will secure all entry points used by the squirrel with steel mesh. From there we will then place a one-way door so that the squirrels n leave but not re-enter. Once all the squirrels have left the house, our team then will seal your roof to prevent future re-entry attempts.
If there were babies, we would have to remove them physilly to ensure their safety. Once our team removes the babies we then place them into a "baby box" near the entry hole to wait for the mother. This is so the mother n reunite with her babies and relote them to a new and safe lotion.
ll us today at 1-866-650-1811 to schedule an appointment for the best Toronto squirrel removal services. We will dispatch a wildlife control technician to your home within 24 hours of your ll. You n also ask us a question via our convenient message form on our contact page.
Damages used by squirrels
Squirrels are extremely agile animals and n rummage through your attic quickly, using damage along its way. They will attempt to chew through anything so wood, plastic and aluminum will most likely be damaged. Since the attic is high, dry and warm it is the ideal nesting lotion for squirrels. They n damage roof vents, roof pipes, soffit, or the roofline to access your attic. Squirrels n use a mess inside your attic by defeting, urinating and chewing on multiple items.
Get Safe and Humane Wildlife Control in Toronto
At 360 Wildlife Control, we focus on providing exceptional humane pest control services to homeowners and business owners in the Toronto-area. Our technicians are skilled in the removal of squirrels, raccoons, groundhogs, skunks, bats and more. Our main goal is to safely remove the unwanted animal from your residence safely. We pride ourselves on our respect for animals and this has made 360 Wildlife Control a go-to choice Toronto squirrel removal and other humane wildlife control. We provide services to Toronto, Markham, Srborough, North York, Richmond Hill, Newmarket, Brampton, Etobicoke, Mississauga and the surrounding cities.
Wildlife Removal Services
One of our skilled technicians will be at your property within 24 hours of your ll. Once there, the technician will execute an extensive 18-point inspection to lote the animal's entry point and to identify the species. From the information gathered, the technician will then create a cost effective plan to safely remove the animal.
It is important to us that our technicians are eduted in animal biology and behavior so that they are prepared for any situations that may arise. They are able to utilize this knowledge in order to remove each species safely. By lling 360 Wildlife Control, we ensure that the removal of the animal will be smooth and ultimately safe for the animals involved.
Repair and Prevention Services
Once the animal is removed from your property it is imperative that they do not return. This is why we offer repair and prevention services.
ll us today at 1-866-650-1811 to schedule an appointment for Toronto squirrel removal services. You n also visit our contact page for more information.
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Toronto, North York, Thornhill, Vaughan, Richmond Hill, Aurora, Newmarket, Markham, Unionville, Srborough, Mississauga, Brampton, Oakville, Etobicoke, Ajax, Maple, Concord


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This page is meant to be a comprehensive site of free, easily available economic time series data useful for economic research, in particular economic forecasting. This site (set of web pages) was started in 1996 to help students in an Applied Forecasting class. The idea was to give students easy access to large amounts of data, and to be able to quickly get charts of that data. This is also useful during class, so that when we use the computer and overhead projector facility in class, we can quickly retrieve series and do manipulations in class.
At this time, there are more than 200,000 time series for which data and custom charts can be retrieved. Though the greatest utility of this site is the vast number of economic time series, and the easily modified charts of that same data, an overlooked facility of great utility is the availability of Excel files for all series.
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text: PDC 2008: BabySmash Preparations October 26, '08 Comments [16] Posted in BabySmash | PDC Sponsored By As I've mentioned before, I've got a talk at PDC this year, it's "TL49" and it's called "Microsoft .NET Framework: Overview and Applications for Babies." It's on Monday at 5:15pm in Room 411. The baby aspect is really secondary, mostly because BabySmash (and what I do with it in the talk) is Not Northwind. This was the strangest Microsoft talk I could sneak past the bosses without them noticing. It also crosses over into other talks and many other products that I'll mention as the week goes on. Stressful times...I'm nervous because: I've never tried to do some many complex and intertwining demos at once. I've never had so many people help out to make it all happen. It may suck. I've got like 7 hours of content to fit in 75 minutes. I've forgotten completely what I'm talking about. ;) I hope enough people show up. Starting to get the pre-show jitters! Here's a teaser of what we were able to accomplish at Tim Huckaby's Party tonight in San Diego. More soon! (That's Clemens Vaster's daughter and yes that's what you think it is. Tim has one at his house. Crazy.) See you at PDC! Technorati Tags: PDC2008,BabySmash « Happy Eighth Anniversary | Blog Home | Tiny Victories Inside Microsoft - Smalle... » About Scott Scott Hanselman is a former professor, former Chief Architect in finance, now speaker, consultant, father, diabetic, and Microsoft employee. He is a failed stand-up comic, a cornrower, and a book author. About Newsletter Sponsored By Hosting By Comments [16] Share on: Twitter, Facebook, Google+ or use the Permalink


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Hooks airport braces for more traffic
Airport officials prepare facility for coming of Exxon, Grand Parkway
Officials at the David Wayne Hooks Memorial Airport in Tomball are paving the way for the anticipated growth expected with the expected completion of the Exxon Mobil campus in Spring and the segments F1 and F2 of the Grand Parkway in 2015.
Since 2011, Antonio Merritt, general manager at the airport, has overseen improvements such as the erection of security gates and fencing around the 680-acre airport, a task that is in the final stages.
"We have all kinds of stuff going on right now," Merritt said. "We didn't have security gates when I got here a year ago, and we are still wrapping the field (with fencing). This is a busy place."
Hooks also is refurnishing a number of aircraft hangars, adding new runway lights and resurfacing both asphalt runways.
Along with the two asphalt runways, Hooks has a rare, 3,000-foot water runway on the property which is the only one of its kind in Texas, Merritt said. The water runway is basically a manmade lake that allows seaplanes or planes that are equipped with pontoons instead of wheels, to take off and land. Hooks will be ready for the expected influx of new patrons by 2015.
Although the improvements are needed, Hooks Airport, which is one of the few general aviation airports in the U.S. with an FAA tower, already is an attractive option for corporate travelers.
A general aviation airport handles flights that are not classified as military or airline.
More Information
At a glance
What: David Wayne Hooks Memorial Airport. Operating since 1963. It supports an average of 275,000 aircraft movements a year and dispenses fuel to general and military aircraft ranging in size from a Cessna 150 to a Lockheed Martin c-130.
Where: 20803 Stuebner Airline Road
Fast fact: The airport, originally Houston Northwest Airport, was named in memory of David Wayne Hooks, the son of the original airport owner Charles G. Hooks. The son died in a plane crash soon after the airport opened.
Details: Go to www.hooksairport.com/ or call 1-800-624-7394
They usually handle any type of flight from something as small as a glider or a powered parachute, to a large cargo plane.
Hooks was named the as one of the fastest-growing and one of the busiest general aviation airports in the U.S. in 2011 by Access Aviation, an aviation consulting firm.
Merritt said Hooks also is adding new aircraft hangars, which will invariably increase the number of patrons who house their corporate aircraft at Hooks.
So far, three hangars have been added to the landscape at Hooks Airport, with two more expected to completed by the end of this year.
Meanwhile, Merritt said he is also working to bring customs inspectors to the airport, which will facilitate travelers from Mexico and Canada.
The only airports in the Greater Houston area that have customs officers are Hobby Airport, Bush Intercontinental, and Sugar Land Regional Airport in Fort Bend County.
"I believe we're going to increase our traffic to this airport from between 25 to 45 percent," Merritt said.
"This was a sleepy little airport, but we have a Department of Defense contract and we get all branches of the military, but getting these corporate jets flying in and out every day is also helping us.
"We have some big-name customers who fly in and out of here."
Some of those customers include H-E-B, Chevron, Baker Hughes, Citation Oil and Gas Corp., which is based at Hooks, and All-American Aviation.
Merritt said it is a strong likelihood that Exxon Mobil will enhance the busy corporate travel hub.
"I really don't think we have any idea the impact Exxon Mobil will have on Hooks Airport and the Tomball community," said Tomball City Manager George Shackelford.
Exxon Mobil may be on the radar for growth in the area, but there are other businesses coming into the area. Companies such as Noble Energy, which is moving into the former Hewlett-Packard complex on Texas 249 this summer, is feeding that anticipated growth in Tomball and fostering a level of excitement at Hooks.
Baker Hughes, already a frequent patron of Hooks, is poised to break ground on the Western Hemisphere Education Center in early 2014.
"It's exciting to see Hooks airport taking advantage of the timing of everything," said Kelly Violette, executive director for the Tomball Economic Development Corp.
"I think they are really looking at sprucing things up and making it ready for the growth we are going to see, not only with Exxon Mobil, but Noble Energy, Baker Hughes and all the companies that are looking at relocating and will use the airport for corporate travel."
Having Hooks within reach of Tomball is an economic advantage for the city in that it can attract new businesses to the area, Violette said.
While cities like Tomball see the economic benefits of their proximity to the airport, other communities are praising the efficiency and the amenities offered for corporate travelers.
Gil Staley, CEO of The Woodlands Economic Development Partnership, said they are not only anticipating an influx from businesses using the airport, but the completion of the Grand Parkway will lessen the commute between The Woodlands, Hooks, and the Exxon Mobil campus.
"The corporate base we have here lends itself to corporate aviation," Staley said. "Our niche market in The Woodlands area is typically corporate headquarters, so corporate aviation facilities like Hooks are vital to our success, and with it being so close, with the completion of the Grand Parkway, this will help us with our recruitment efforts, as well as those companies who want to expand here."


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METAL INQUISITOR "Ultima Ratio Regis" – A True Heavy Metal Album You MUST Own!
5 Metal Fists Out Of 5!
The Metal Warriors known across our lands as METAL INQUISITOR have a new studio album releasing this February 21st, via Massacre Records and it explodes with True Heavy Metal glory, speed, riffage, eye-popping guitar solo's, kick-ass vocals, 10 memorable songs and an undeniable spirit of what Metal is ALL about! Ultima Ratio Regis is a Metal album you MUST seek out and own! Praise the Metal Gods that Metal Inquisitor exists!
For ALL of you old school Metalheads out there, this is a True Heavy Metal album that you will ALL be telling your fellow Metal brethren to buy and hail! My Metal God almighty, does this band from Koblenz, Germany know how to shred, ignite the Metal senses and profess the True Heavy Metal gospel! Yes, Virginia, the album cover artwork does dictate just how outstanding the Metal you'll hear within is!
El Rojo on vocals slams it home, while the entire band screams legendary Metal talent, through these 10 songs. I'm NOT blowing Metal wind out of my ass here, Metal Inquisitor have paid their Metal dues and are a True Heavy Metal band that has erupted ALL the Metal goodness that flows within my Metal veins. Ultima Ratio Regis is an album that I cannot recommend any more highly than I've already tried. Metal Inquisitor and Old school Metalheads shall know what I mean.
Metal Inquisitor and their new album will have fans of Witch Cross, Satan, Sinister Realm, Manowar, Grim Reaper, Crystal Viper, Iced Earth, (early) Judas Priest and (early) Iron Maiden, salivating at the mouth. I am incredibly psyched-out that the Metal sounds of Metal Inquisitor are in my Metal blood for the rest of my Metal life. Metal be thy name. – Stone
Ultima Ratio Regis – Track Listing:
01. Confession Saves Blood
02. Burn Them All
03. Call The Banners
04. Black Desert Demon
05. Bounded Surface
06. Death On Demand
07. Self Denial
08. Servant Of State
09. The Pale Messengers
10. Second Peace Of Thorn
Blumi – Lead Guitar
T.P. – Guitar
El Rojo – Vocals
Havoc – Drums
Cliff Bubenheim – Bass
* For more info on METAL INQUISITOR:
Facebook: Metal Inquisitor
Website: http://www.metalinquisitor.de
Website: http://www.massacre-records.com
This entry was posted on February 2, 2014 at 1:05 am and is filed under Heavy Metal, heavy metal bands, Metal, metal bands, metal music, Music, news, rock music, rock music news, world news with tags metal albums 2014, metal inquisitor, Metal News, metal odyssey, true heavy metal, true metal bands, ultima ratio regis. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.
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School psychologists provide assessment and other services to students from birth through age 21. School Psychologists evaluate eligibility and continuing need for special education services as a part of a multidisciplinary team. School Psychologists evaluate and complete assessments that address various needs in cognitive functioning, emotional/behavioral functioning, Autism Spectrum Disorder, and adaptive and functional skills.
Services include:
- Administering psychological and educational tests, and other assessment procedures;
- Interpreting assessment results;
- Obtaining, integrating, and interpreting information about child behavior and condition
- Assisting in developing positive behavior strategies;
- Participating as a member of the intervention team (I-Team) to provide support in developing appropriate interventions to support emotional, behavioral, and mental health needs in the educational setting.
Student Services Contact
Courtney Holmes


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But not too long ago when I made my Southern Buttermilk Cat Head Biscuits I asked my grandmother how I was supposed to get my biscuits to be as soft and tender as possible. "Oh honey, what you need is lard. That makes biscuits melt in your mouth good". Hhhhmmm. Did I really want to go that route?
After a little research I surprisingly found the answer to that question to be "yes". Unbeknownst to me, homemade lard made from fat that you render yourself is actually the most healthy fat when stacked up against butter and vegetable shortening. True lard contains less bad fat and more good fat than butter, and is still better for you than the vegetable shortening due to the process of hydrogenating the shortening to make it able to withstand sitting out un-refrigerated.
But hold your horses before you get all excited and rush out to buy the packaged lard sitting next to the crisco thinking it's your new, healthy go-to. You can certainly buy this, but it won't be anywhere near as healthy as the kind you render at home due to the hydrogenating process I mentioned. I've never seen any, but the kind of lard that is the healthier option is the kind that would be sold in the refrigerated section of the grocery store.
To make your own lard all you'll need is some fat back. Sounds delicious, huh? But the good news is that this is super easy to make, and once you use it to make biscuits or pie crusts you'll never want to go back!
Homemade Lard
fat back
Rinse fat back of any salt used to cure it. Dice fat into small cubes (the smaller the pieces, the more fat you'll be able to render) and add to stock pot along with just enough water to cover bottom of pot by 1/4 inch. *I used an iron skillet, but I believe it would have been easier to use a deeper pot.*
Turn heat on medium high. Make sure to stir the fat about every 10 minutes to ensure that it's not sticking to the bottom. After about 20 minutes the fat will begin to melt and the water will evaporate. Continue cooking for an additional 30-40 minutes (50-60 minutes total). By this point "cracklings" will have formed (small brown bits that are left once all of the fat has been rendered).
Remove cracklings with fine mesh strainer and set aside. These bits serve as divine additives to other dishes as a source of flavor. It's kind of like adding bacon bits.
Place a cheesecloth over a glass jar (I used a coffee filter because I didn't have one one hand) and secure with a rubber band. Pour melted fat over the jar. The cheesecloth will catch any residue so that you are left with pure lard.
This may take a while for the melted fat to pass through the cheesecloth because it's much thicker than water. Just be patient though :)
The melted liquid will be a brown color, but will lighten after it cools in the fridge.
Ta da! The final product
Keep stored in a tightly seal container in the fridge.


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INDIANA, Pa. (AP) - A western Pennsylvania man has been sentenced to one to five years in prison for helping a woman purposely overdose on prescription medications then slowing the police response to ensure she'd die.
Brandon Lee Crowe, 31, of Arnold, was sentenced Monday after acknowledging that he helped 39-year-old Julie Madeley take a fatal dose of the antipsychotic medication Seroquel at her Indiana County home. She died hours later at a Pittsburgh hospital on March 28.
District Attorney Patrick Dougherty argued that Crowe also interfered when a state trooper arrived with Madeley's daughter to check on her. Crowe repeatedly told police Madeley wasn't home before troopers found her unconscious - and Crowe packing some of Madeley's jewelry and other property into his car - before he let them enter her apartment after about 15 minutes.
Crowe pleaded guilty in September to charges of aiding suicide and obstructing emergency services after prosecutors dropped charges that he took Madeley's jewelry and other items and planned to sell them.
"I find troubling your actions at the time this crime took place," Common Pleas Judge Thomas Bianco said in imposing the sentence.
Crowe apologized and his attorney, Aaron Ludwig, noted that Crowe has undergone drug and alcohol counseling and taken a parenting class since he was jailed on the charges months ago.
Dougherty filed the rarely used charge - which carries up to 10 years in prison - because further investigation has made it clear Crowe knew Madeley was attempting suicide, including his acknowledgement that her breathing was labored as he kept police from entering her apartment.
Crowe met Madeley online 11 days earlier and moved in with her and another man. She wanted him to leave after several days, but Crowe threatened suicide and stayed - and then eventually helped Madeley commit suicide instead, police said in a criminal complaint.
Crowe took some personal items from Madeley - including jewelry she was wearing - after she consumed the drugs, police determined.


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She said "Jay I'm yours
I've been screaming for the past three days I'm hoarse,"
She was spinning like she'd never seen waves before
So I gave her a boat, and an oar
And a star to guide her safely to the shore
She said she'd never believe in Moses and Noah
Unless I show her, so I showed her
Gave it right to her like I owed her
That's when I changed from Shrek the ogre
Into Master Yoda
She said "oh I, can't believe uh, it's a miracle
It's a bird, it's a plane, it's a spherical
Object, hard to detect, right out the projects
He can move mountains without flexing a bicep,"
Speaking strange dialect, I start dropping jewellery
Her eyes went googly, she went home and Googled me
Myspace friend requested and Youtubed me
A hundred thousand views of me
Buildin' me a manor on the backs of wack rappers
Out here spitting that foolery
She logged on to Gmail, clicked compose
And said "I don't do this usually
Nas said Hip Hop was dead
And what these niggas out here spitting is just eulogy
You represent the new to me, true, cats is nice
But I ain't see the God since Hova spit that navy blue to me
Truly yours, don't let me down like Lennon
The greats pay the sacrifice in they early beginnings
P.S., 'LL' rocked the bells, now it's your time
Your train is running on schedule, 'LOL', showtime
I hear your name ringing, I feel the game changing
Niggas know, every time you spit
It's like Rakim in his flag
Spitting flames with his chain dangling
Barack Obama with his dame way out in Maine wrangling
The game will swallow you if you ain't strong enough to make it follow you
I'd pack my bags and head home if I was you"
This song can be heard/read two ways.
"She" is Hip Hop, a not uncommon personification that is only revivified here.
"She" is the average Hip Hop listener who has given up hope that another great Rap talent will emerge in this climate.
"She" is probably meant to be both.


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Spaniard Marc Casanovas began diving in 1996 and was so inspired by what he saw he immediately began underwater photography. He's hosting our @suuntodive Instagram account this week. Follow along to see his incredible images from dives in the Mediterranean!
© Marc Casanovas
Tell us about yourself?
My name is Marc Casanovas, I live in Vilassar de Mar, near Barcelona, and I have been an underwater photographer for 20 years.
Where do you like to dive?
I regard myself as a Mediterranean photographer, because 95% of my work is concentrated a few kilometres from my home. I firmly believe that a photographer's best photos are taken near where they live.
© Marc Casanovas
What inspires you in the underwater world?
The fact that it never ceases to surprise me. What gets me hooked is observing nature. You always encounter different animals in a dive, or capture a new kind of behaviour.
The advantage of photography is that it is virtually infinite, even if you hardly move away from where you live. Nevertheless, I am thinking about taking a trip somewhere – we can never stop!
© Marc Casanovas
How would you describe your photography style?
I would say that I am a nature photographer. What I mean is that I do documentary photography, without ever losing sight of the fact that photography is based on aesthetic concepts.
Is there a story you wish to tell with your images?
Any photograph that tells a story at a glance, without the need for any explanation, is very likely to be a good photo. And that is what I try to do when I dive with my camera.
Where to follow your adventures?
People can follow me on my Flickr page, on Facebook or on my website.
Follow @suuntodive on Instagram


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The "Fun Time Beach" cafe in Gaza was hit by an Israeli air strike yesterday night while people were watching the semi-final of the FIFA World Cup. Nine people were killed in the attack.
Representatives of the United States government told the Palestinian Authority yesterday that Israel is refusing to stop its attack on the Gaza Strip. Netanyahu said so himself, just hours later, that a ceasefire is "not even on the agenda."
Israeli Intelligence and Strategic Affairs Minister Yuval Steinitz spoke explicitly on the BBC about Israel's plans to completely reoccupy Gaza and to keep it under military occupation. The Israeli military is currently amassing tanks and thousands of troops (40,000 reservists were officially called up yesterday) along Gaza's borders. As Israel ratchets up its airstrikes and threats of an imminent ground invasion become more real by the minute, it is important for us to grasp the true danger of this situation. A ground operation in Gaza will likely kill thousands of Palestinians. During Israel's two previous smaller operations in Gaza (2008/9 and 2012), The Israeli army killed approximately 2000 Palestinians, including 500 children.
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Petition against officer involved in shooting delivered
MADISON, Wis. — A petition requesting that the officer involved in a fatal shooting be kept off the streets was delivered to the Madison Police Department Friday.
Officer Steven Heimsness shot and killed Paul Heenan in November when he responded to a report of a home burglary.
More than 100,000 people signed the petition against Heimsness, and four people delivered it Friday.
Amelia Maurer, one of the deliverers, said Police Chief Noble Wray has declined to meet with her and others asking for Heimsness to be removed.
According to MPD spokesperson Joel DeSpain, Wray anticipated receiving the petition and wants to hear from citizens regarding the case.
"He has met in the past with those pushing the petition drive, and is willing to meet with them again after he reviews the petitions," DeSpain said of Wray.
Maurer said she and other friends of Heenan have begun a second petition asking that an impartial body investigate the shooting.
Heimsness remains on paid administrative leave. He is currently the subject of three other internal investigations not involved in the Heenan shooting.


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Khuzaa was one of the villages that was hit the hardest during the 50-day military campaign.
Amnesty International has accused Israel of committing war crimes during its military campaign in Gaza this summer.
A report released by the group on Wednesday says Israel displayed "callous indifference," launching attacks on family homes in densely populated areas throughout the coastal strip. In some cases, its conduct amounted to war crimes. The report adds that Palestinian militants also perpetrated war crimes.
The report, entitled Families Under the Rubble, examines eight cases of targeted Israeli strikes that killed at least 111 people, 104 of whom were civilians, 62 children in all. Amnesty says it has "significant doubt" as to whether there was a clear and present military objective in some of the cases, something that could make the strikes a war crime.
"In all the cases documented in this report, there was a failure to take necessary precautions to avoid excessive harm to civilians and civilian property as required by international humanitarian law," the report said.
"The report reveals a pattern of frequent Israeli attacks using large aerial bombs to level civilian homes, sometimes killing entire families," Amnesty said in a statement put out along with the report.
During the 50-day military campaign, 2,192 Palestinians were killed, including 1,523 civilians, and approximately 18,000 homes were destroyed, according to statistics from the United Nations. Israel, which lost 64 soldiers and six civilians and endured disruptions due to the threat of Hamas' missiles, said it took every precaution to minimize civilian casualties, but that its efforts were hindered because Hamas used Gaza's civilian population as human shields.
Whether or not Hamas members are guilty of hiding in civilian areas, the report is scathing in its criticisms of Israel's blatant disregard for the lives of noncombatants.
"In those cases where Amnesty International has been able to determine the possible military target, it has found either that in fact it was not a military objective, that the devastating toll on civilians and civilian property was out of all proportion to any military advantage from the attack and/or that Israel failed to take necessary precautions to minimize harm to civilians," the report reads.
In the eight cases investigated by Amnesty, no prior warning was given to the homes' occupants, despite Israel's insistence throughout its military campaign that it always warned Palestinians to evacuate the structures before bombing.
A statement issued by the Israeli embassy in London questioned the reliability of Palestinian fieldworkers employed by Amnesty in the Gaza strip who gathered testimonies for the reports, saying their work "serves as a propaganda tool for Hamas and other terror groups." Amnesty says it was forced to rely on locals to gather testimonies and information because its regular employees were barred by Israel from entering Gaza.
Amnesty called on Israel and the Palestinians to "accede to the Rome statue and grant the ICC [international criminal court] the authority to investigate crimes committed in Israel and the occupied Palestinian territories."
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