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Game Of Thrones took Memorial Day weekend off and was replaced by Behind The Candelabra, temporarily. I'm OK with that. And I'm OK with an extended penultimate episode for The Rains Of Castamere. At least that's what I think I read somewhere (which I can't find right now so if I'm wrong I'm sorry).
The trailer for Episode 9 is below. You'll recall, Episode 9 for Season 2 is when Blackwater happened. Blackwater was... well... some say it was one of the greatest tv episodes OF ALL TIME.
So, you know, expectations are high for The Rains Of Castamere. It airs on Sunday on HBO Canada and HBO. And it's the reason why I might not be with it on Monday. Because I get back from LA at 11pm that night and I'm also on a deadline this weekend so if I have to finish my draft first, then watch it at 3am, it'll be an all-nighter. Still... it will be worth it, right? God if my PVR chooses that day to be a goddamn c-nt it might get violent. Wait. I just checked my PVR. It's saying it's only a regular hour. But sometimes the TV listings aren't properly updated. I pre-recorded 2 hours just in case.
Here's Kit Harington in Toronto earlier this week. God would that f-cking Catelyn Stark just die already?


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|July 2010
On a recent walk through Oller Cemetery, I came upon the walnut tree again. Where was Baby Spong's marker? Was it was not this tree? Had someone stolen the broken marker?
Within moments I saw it: Repaired, off the damp ground, resting against a larger gravestone.
|October 2010
Memory of
an Infant
son of Absolum &
Mary Spong born
Oct 17, 1835.
How great to see signs of extra care in Oller Cemetery!

subset: commoncrawl


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Keith Urban Not Returning to 'The Voice' Until His Album Is Done
Although Keith Urban has fully enjoyed coaching talented singers on 'The Voice' in Australia, there's no chance that the 'You Gonna Fly' hitmaker will trade in his guitar for a permanent reality TV contract anytime soon. While Urban would be thrilled to do another season of 'The Voice,' he told Australian radio's Kyle & Jackie O Show that making music is still priority No. 1.
"My thing is making sure I have an album done," Urban said. "Mostly I'm just going to be in the studio for the next [few] months. If the record comes together the way I hope it does, I'll definitely be there [on 'The Voice] next year, and if it takes longer, then I'll have to figure out how I can make it work."
Urban hasn't said for certain when his next disc will hit shelved, but he did say earlier this year that he's working 'feverishly' to explore new stories in his life and work with talented songwriters for the album.
"My intention for the record is to start exploring the stories in my own life," the hitmaker said. "There's plenty of them, and I've been through a lot of things and there's a lot more of that exploration that's happening already. I think it is taking shape a little bit. It feels like it's the first one."
If all goes according to plan, Urban will commit to another season of 'The Voice.' But even if the 44-year-old country star has to ditch his reality television gig, he promises that he'll still support 'The Voice.' and those who try to achieve success via TV competitions. For now, Urban says he's "jonesing to get back on stage anywhere … anywhere sometime soon."
Luckily, he has a 2013 tour in the making. All of the confirmed dates are listed here, and we're sure more will be added in the coming months.


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Slightly more than 60 percent of respondents to this week's RBJ Daily Report Snap Poll oppose New York requiring firms to provide paid sick leave.
With this year's unusually severe flu outbreak has come renewed debate over the issue of paid sick leave, which is not mandated by the federal government or 49 of the 50 states.
In New York, roughly 38 percent of private-sector workers are employed by companies that do not provide paid sick leave, according to the Institute for Women's Policy Research. Nationally, 40 percent of private-sector workers and more than 80 percent of low-wage workers do not have paid sick days, the National Partnership for Women & Families reports.
Connecticut has enacted legislation mandating paid sick leave; it took effect in January 2012. Seattle, San Francisco and Washington, D.C., also have mandates. Legislation has been introduced in Washington and in Albany, among other state capitals. The Paid Sick Leave Act introduced in Albany would require firms with fewer than 10 employees to provide up to 40 hours of paid sick leave annually; all other businesses would be required to provide up to 80 hours.
Proponents say mandated leave is needed because many people who cannot afford to stay home and lose pay go to work when sick, spreading illness to co-workers. Also, lower-paid workers in food service, retail and health care industries are least likely now to have paid sick leave.
Opponents argue that businesses would respond to higher mandated costs by reducing workers' pay or cutting jobs. In addition, a mandate purportedly would encourage some employees to game the system, forcing their co-workers to carry a heavier burden.
More than 640 readers participated in this week's poll, conducted Feb. 11 to 13.
Should New York require firms to provide paid sick leave (five days annually for firms with fewer than 10 employees, 10 days for all others)?
No: 61%
Yes: 39%
When will the guilt-ridden do-gooders realize that every new law is slowly destroying our country? Please let the free market take care of things. After almost 240 years, it works pretty well.
—T. Alan, West Henrietta
Common sense with regard to public health and human decency dictates paid sick leave.
—Eve Elzenga, Eve Elzenga Design, Interiors
I think that New York should require all firms to provide five days' paid sick leave annually. Ten days would be very difficult to manage in my business of 25 employees. With two weeks' paid vacation and two weeks' sick leave, that would be a full month off for each person. That would mean I would need to have an added two employees cross-trained to cover the off time of staff. The 10 sick days would require one added staffer to cover that. However, I think that five days allows for taking paid time off for flu or colds or other basic illness.
—Jim DeLuca, Abundance Cooperative Market
New York (Albany) should be responsible to keep businesses in New York, not try to create means to have them leave or go out of business. One thing New York and Washington have in common is that they are totally out of control.
—Joe Burke
All of our employees who work full time receive five days of sick leave, and it is pro-rated for those working half time or greater. It is extremely difficult for low-income employees to forego work in the case of illness, which leads them to work and spread infection to other employees or clients. I believe some sick leave is appropriate. However, 80 hours per year is prohibitive in cost, especially for any company that has not provided any sick leave up until now.
—Betty Mullin-DiProsa, president and CEO, St. Ann's Community
You want to chase more small businesses out of New York? Just pass this legislation and watch what happens. As a business owner with fewer than10 employees, I'd take steps to reduce the number of employees below 10 while looking to create any new jobs in a more business-friendly state. The authors of this bill must have never had their own business.
—Mark Redding, Poseidon Systems LLC
As we experience severe flu seasons, it's important that people be able to stay home to minimize the spread of illnesses. Also, the use of sick leave should not be limited to the individual's illness but should apply to children or dependents who require care.
—Kate Krueger
I am sure the proponents of this mandate do not know a thing about running a business. Taxing a profitable business, I can understand. Forcing a for-profit business to pay for expenses is bordering socialistic and the only effect is to drive business away from New York State. Not every business is profitable. Many business owners make personal sacrifices to build their business. Are you telling them to work harder and make less (or lose more) so employees can get pay for not producing 10 more days a year? There are enough state and federal mandates burdening businesses large and small. If people wonder why the unemployment rate is stubbornly high, just look at the disincentives the government has invented to tell employers not to hire. Plain and simple.
—Patrick Ho
This would just be another example of New York State causing its businesses to be at a competitive disadvantage when compared to neighboring states. Paid sick time should be a decision left to every employer. Government needs to learn to keep their cumbersome hands out of private business.
—Matt Convery
While it is a novel idea, adding the additional burden of this expense on small-business owners will prove to be crippling. No small-business owner has sick time; they can be sick but don't have the luxury of paid sick leave. In New York we already have exorbitant insurance expenses, thanks to the scaffolding laws. The sick leave policy should be left up to the business owner, who can assess the financial implications on the organization.
—John Stevens, owner, ICM/R.S. Media
I've worked for myself for much of my life. I don't work, I don't get paid. When I look at the amount of time taken by those people who think they have to use their sick time or lose it, it is appalling. The consumer or the taxpayer always picks up their tab.
—Angelo Mancuso, White Hot Films
So Connecticut makes a huge assumption and it should be the law of the land. What if they are wrong? Who will pay for this? How do we ensure that people are actually sick when they take sick leave? Shouldn't everybody get the same sick time, the same vacation time, the same pay and benefits? That is the only thing that is fair. Let's pay everybody's health insurance, raise minimum wage to whatever Warren Buffett makes and we will all be happy, healthy and rich! I'll sue you for everything you are worth, and you do the same to me! Who is John Galt?
—Bill Lanigan
Paid sick leave is another "perk" that can be (and frequently is) easily abused, just like workers' compensation insurance. We have unpaid leave laws on the books already. Let companies decide, based on their own circumstances. We don't need our poorly managed and run government telling our successful companies how to do anything else. They already have more than they can handle just trying to operate in New York.
—George Thomas, Ogden
Of course businesses should be required to pay people to stay at home. There should also be paid flat-tire days. Businesses should also pay overtime to employees tardy because of trains (while they wait). Complementary breakfasts, lunches and dinners with doggie bags should be mandatory and on the clock. Any time spent in the bathroom facilities should be added as comp time to allow employees build up extra days off with pay. If the job we're talking about is in manufacturing, employers should install machines and equipment in their employees' garages to eliminate commuting to work. The people who get stuck traveling to work should get paid to do so—both ways. How about pay for thinking about work? If people are at home on the weekend and think about work, just inform your boss and he should add those hours to your paycheck. This is the best one—if an employee is out on paid vacation and gets sick, they have to get double time! Is anyone else sick (pun intended) and tired of idiots who do not create anything, making policy or decisions for the people who do? Fools couldn't run a project, much less a company. On the other hand, for the people who don't have generous benefits, find another job. There is a reason low-wage workers don't have benefits comparable to high-wage workers.
—Lou Romano
On the federal level, the Family and Medical Leave Act should be expanded to cover more workers and to provide at least some weeks of pay, beyond the individual worker's paid sick leave. Very few workers can afford to take advantage of the full benefit of FMLA because very few workers can afford to go that long without pay. In the absence of federal action on this issue, New York State could create a state version of FMLA with a similar requirement of paid leave.
—Lola Kelly
The details for this are crucial. Any mandated paid sick time should be restricted to a situation where, due to their own medical condition, the employee is unable to reasonably perform their duties or is a hazard to others in the workplace. Unpaid absence should be permitted for the many other circumstances that cause employees to miss work. To permit a mandated program to be as open-ended as many of the voluntary sick-leave programs is to foist yet another government-based expense on the private sector.
—D. Kennedy, Webster
I have worked for a small-minded employer of fewer than 40 people in Geneseo who offered no paid sick leave. If you were ill, you either used your vacation time or went in to work because you didn't want to lose your vacation time subsequently infecting the entire office. Employees were treated poorly to begin with, and inadequate policies like unpaid sick leave only aggravated an already lousy work environment. If employers don't have enough decency or common sense to offer paid sick leave, then the government should make it easy for them and mandate it.
—M. Curtain, Rochester
I don't believe anyone should be required to pay for sick days, there is supplemental insurance for that reason. Most companies have to pay overtime or bring someone in to cover for a sick person so they are paying double when a person is out sick. I think the worst example of paying for sick days is in the education field. We contract with a superintendent of school and agreed to pay them a sizable fee to work 12 months a year. We throw in a large about of vacation time and a fair about of personal days, then we give them sick days. We have already agreed to pay them for 12 months. When they take a sick day, does the money to compensate them for the sick day come out of another fund someplace? When they leave a school district to move on or retire, we pay them a second time for all the sick days they didn't use. Aren't we paying them twice for the unused sick days?
—John Weaver, retired
Please! I say this gender neutrally: Man up!
—Jay Birnbaum
It depends on the position. If the employee can't work from home, then yes, they should have sick time. But for a salaried position where the employee can work at home, it seems unnecessary. And, quite honestly, something like a nagging minor cold is more vacation-day-worthy than sick-day-worthy.
—Eric Bourgeois
We have far too much "something for nothing" already, and who would control the abuse? If a merchant does not sell a thing all day, who steps in and picks up the expense? There is your answer!
—J.A. DePaolis, Penfield
This is another government intrusion. I would agree if they also added a mandatory small-business profit minimum. Then if a company could not make a profit because of all the government mandates, the government would guarantee a reasonable profit to small business. This would be paid by the government, which obviously has the money! A business that does not offer competitive benefits will lose out in the labor market in the long run.
—Eric Muench, president, Genesistems Inc.
While I believe that offering some time off for sick leave makes good business sense for most companies, I resent the fact that state government is yet again dictating to business another law. The RBJ just polled their readers on the state's proposed minimum wage issue. When will our state get out of the way and let business owners decide for themselves what is best for their businesses? New York is "open for business." Really?
—Mike Charland, Webster
Eighty hours?!
—John Schantz Jr., Schantz Homes Inc.
We provide five paid days a year for personal time which includes sick time, medical appointments, or special occasions for which our employees may wish to take off. If we are required to provide five paid days exclusively for sick days, then we would have to eliminate the personal days. Also if we are required to provide them, are we required to accumulate them if they are not used? When you add vacation time (two to three weeks), holidays (seven) days, and personal time (five days), you are providing four to five paid weeks off. It's important to take care of your good workers. Forcing companies to pay 10 days of sick leave is excessive and drives up the selling price of their products, making them less competitive and their products more expensive to the consumer. Excessively paid employee benefits helped put the entire European economy in horrible shape and that is where we are headed with this kind of proposal for paid 10 days. Then people cry about outsourcing and work getting shifted to overseas. Companies can't keep giving more, they choose options to keep their costs down. If productivity increased proportionally than that would offset it, but it doesn't.
—Bill Cox, Marktec Products Inc.
Let's join the rest of the industrialized world!
—Tom Gillett, NYSUT
This state pushes us around more than enough. I wish I could relocate to Texas; these laws may force me to. My staff has paid time off. They can use it to be sick or go to Hawaii. If the week becomes mandatory, they will still get the same paid time off.
—Daniel Mossien, architect
Whatever. Aren't we supposed to be making New York a business-friendly state? Doesn't anyone else think that if a startup was looking for a home, they would be fleeing New York State like a startled deer?
—Lou Calarese, Applied Audio and Theatre Supply
Mandated? No way. Paid sick leave? Why beg to be lied to? Just allot a number of days for planned and unplanned that are paid. Why bother entertaining what they are for?
—Doug Strang, S&S Engineering PC
New York is already the most regulated state in the nation. We don't need more regulations with know-nothing politically connected bureaucrats to administer the regulation. Paid sick leave is already a highly abused benefit. Common sense employers that haven't already left the state will make appropriate accommodations for persons that need paid time off for legitimate sick needs.
—Jim Weisbeck, Bloomfield
All time-off benefits (vacation, paid time off and sick time) should be bundled under one accrual and earned with each paycheck, then taken as needed, whether planned or unplanned. Management should have the right to send a sick employee home if deemed to be a risk to other employees or clients/patients/residents.
—Rich Mileo
What a great idea! But, just to make sure that nobody thought of the two weeks of paid time off as extra vacation days, we should mandate that everyone has 10 weeks of paid vacation. (Five weeks if you have fewer than 10 employees). We would have so much vacation we would never need to abuse sick time. Then we should follow up with a law requiring everyone to make a million dollars a year. Everyone would be millionaires! Think of all the income tax revenues!
—John Crowley
2/15/13 (c) 2013 Rochester Business Journal. To obtain permission to reprint this article, call 585-546-8303 or email firstname.lastname@example.com.


text:
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Artificial intelligence can identify at-risk patients, inform care and improve disease prevention
There's no shortage of buzz around artificial intelligence and its potential impact on a variety of areas within healthcare, from patient care to revenue cycle operations. There is an emerging trend toward AI assets that amplify the value of patient data and provide an extendable, scalable pathway to effective primary disease prevention. That's something that… Read More »


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Siege of Angband
The Siege of Angband was the 400-year leaguer of the Noldor around the fortress of Morgoth in the early centuries of the First Age, which began following the Dagor Aglareb. The Noldor and their allies possessed insufficient force to assault Angband directly.
In the west Fingolfin and Fingon guarded the pass over Ered Wethrin into Hithlum from Barad Eithel, while Finrod and Orodreth held the pass of Sirion from Minas Tirith and Angrod with Aegnor held the northern slopes of Dorthonion to the borders of Aglon. In the east the Sons of Fëanor held watch; Celegorm and Curufin held the land between the rivers Aros and Celon, Maedhros had his stronghold on Himring while he guarded the Marches north of that hill and the plains between the rivers Celon and Gelion, Maglor kept watch over the northern hills of the river Gelion, and Caranthir in the shadows of Ered Luin.[1]
It was during the Siege that Turgon's people left Nevrast to build Gondolin. Other Elven cities, Brithombar and Eglarest were also established by the Sindar on Falas, and Nargothrond, the realm of Finrod. The siege was incomplete, as Morgoth was still capable of sending out various forces of orcs to harass the elves, such as the attack of Hithlum; but the Noldor were grown strong enough, that these task forces posed no significant threat.
After the defeat of Glaurung, a period called Long Peace begun. The Men of the House of Bëor entered Beleriand and were followed by the Haladin
Years after the Battle of Aglon Pass, the Forest of Brethil was given to the Haladin. A final band of Men, the House of Hador, came to Beleriand; they were given the lands of Dor-lómin.
After about four hundred years, the Siege was broken in the Dagor Bragollach.
- ↑ J.R.R. Tolkien, Christopher Tolkien (ed.), The Lost Road and Other Writings, "Part Two: Valinor and Middle-earth before The Lord of the Rings, III. The Later Annals of Beleriand" pp. 127-8


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HOW HOLLYWOOD BECAME THE NEW AMERICAN DREAM by Savannah Renae Haspel A Thesis Presented to the FACULTY OF THE USC GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree MASTER OF ARTS (STRATEGIC PUBLIC RELATIONS) December 2011 Copyright 2011 Savannah Renae Haspel
Object Description
|How Hollywood became the new American dream
|Haspel, Savannah Renae
|Author email
|Master of Arts
|Document type
|Degree program
|Strategic Public Relations
|Annenberg School for Communication
|Date defended/completed
|Date submitted
|Date approved
|Restricted until
|Date published
|Advisor (committee chair)
|Floto, Jennifer D.
|Advisor (committee member)
LeVeque, Matthew
Ross, Steven J.
|The American Dream is being Subjugated by The Nation's Growing Celebrity Worship and Replaced by the Hollywood Dream. ❧ Almost everywhere one looks, celebrities now dominate the American culture. From television shows to household products, Hollywood has burrowed itself into nearly every aspect of people's lives. Many people not only want to emulate celebrities, but more and more want to actually become celebrities, too. This growing trend has impacted the attitudes and aspirations of the nation's youth, shifting from the once-revered hard-working American Dream to the ego-driven Hollywood Dream. This change did not happen overnight; it has been hundreds of years in the making, but has accelerated with a series of events in the last two decades. ❧ History shows that societal and cultural attitudes tend to shift over time. While humans all share the same basic biology needs, major occurrences like wars, economic conditions and technological advancements shape each generation's view of the world. This is now evident as many of the Baby Boomers (age forty-seven to sixty-five), who lived the American Dream, share a vastly different view of success than the majority of their children, the Millennials (age fifteen to thirty-one) do now. Many of the Millennials find it difficult to associate with their parents' aspirational views of America, where hard work brought prosperity, and have therefore sought a convenient shortcut: The Hollywood Dream. ❧ From the burgeoning middle class to the invention of movies to the Internet, much of society's ambitions have move from the family to the individual and the ego. Therefore, it is crucial to understand the different attitudes and motivational drivers for two of the nation's largest and most influential age groups: The Baby Boomers and the Millennials. Because of their enormous presence and buying power, and vast attitudinal differences, knowing how to craft messages and "speak" to these groups will be highly beneficial for public relations practitioners. ❧ This paper will compare celebrity fascination across generations and determine the underlining causes of how the Hollywood Dream replaced the American Dream. Additionally, it will identify key messages and tools that public relations professionals can use to effectively connect with this group.
|celebrity; worship; obsession; fascination; gen Y; millennials; hollywood; american dream; attitudes; beliefs; baby boomers; work ethic; expectations; entitlement; narcissism; psychology; fame; reality; television; family structure; parenting; childhood development; alternatives; history; stars; mental health; imaginary audience; emerging adults; theory; extended adolescence; escapism; mirror effect; schadenfreude; gossip; tabloids; paparazzi;entertainment; movies; society; generation me; sociology; consumer; luxury; lifestyle; aspirational; United States; America; shrinking; middle class; debt; technology; unhappiness; hopelessness; twitter; facebook; social media; new media; public relations; marketing; over consumption; banana republic; wealth; disparity; income; fans; fanatic; sycophantic; Internet; youtube; young adults; teens; tweens; tools; communication; strategies; tactics; workforce; workplace; differences
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|Haspel, Savannah Renae
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|HOW HOLLYWOOD BECAME THE NEW AMERICAN DREAM by Savannah Renae Haspel A Thesis Presented to the FACULTY OF THE USC GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree MASTER OF ARTS (STRATEGIC PUBLIC RELATIONS) December 2011 Copyright 2011 Savannah Renae Haspel


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You are here: Home > Prescription(RX) Drugs > P > Phenytoin Sodium (Hospira, Inc.)
phenytoin sodium injection, solution
----------Phenytoin Sodium
Injection, USP
This drug must be administered slowly. In adults, do not exceed 50 mg per minute intravenously. In neonates, the drug should be administered at a rate not exceeding 1-3 mg/kg/min.
Phenytoin Sodium Injection, USP is a sterile solution for intravenous (no infusion) or intramuscular use, containing in each mL phenytoin sodium 50 mg, propylene glycol 0.4 mL and alcohol 0.1 mL in Water for Injection. pH 10.0-12.3; sodium hydroxide added, if needed, for pH adjustment.
Phenytoin sodium is related to the barbiturates in chemical structure, but has a five-membered ring. The chemical name is sodium 5,5-diphenyl-2,4-imidazolidinedione. The structural formula is as follows:
C15H11N2NaO2 MW 274.25
Phenytoin is an anticonvulsant which may be useful in the treatment of status epilepticus of the grand mal type. The primary site of action appears to be the motor cortex where spread of seizure activity is inhibited. Possibly by promoting sodium efflux from neurons, phenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. This includes the reduction of posttetanic potentiation at synapses. Loss of posttetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas. Phenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of grand mal seizures.
The plasma half-life in man after intravenous administration ranges from 10 to 15 hours. Optimum control without clinical signs of toxicity occurs most often with serum levels between 10 and 20 mcg/mL.
A fall in plasma levels may occur when patients are changed from oral to intramuscular administration. The drop is caused by slower absorption, as compared to oral administration, due to the poor water solubility of phenytoin. Intravenous administration is the preferred route for producing rapid therapeutic serum levels.
There are occasions when intramuscular administration may be required, i.e., postoperatively, in comatose patients, for GI upsets. During these periods, a sufficient dose must be administered intramuscularly to maintain the plasma level within the therapeutic range. Where oral dosage is resumed following intramuscular usage, the oral dose should be properly adjusted to compensate for the slow, continuing IM absorption to avoid toxic symptoms.
Patients stabilized on a daily oral regimen of phenytoin experience a drop in peak blood levels to 50 to 60 percent of stable levels if crossed over to an equal dose administered intramuscularly. However, the intramuscular depot of poorly soluble material is eventually absorbed, as determined by urinary excretion of 5-(p-hydroxyphenyl)-5-phenylhydantoin (HPPH), the principal metabolite, as well as the total amount of drug eventually appearing in the blood.
A short-term (one week) study indicates that patients do not experience the expected drop in blood levels when crossed over to the intramuscular route if the phenytoin IM dose is increased by 50 percent over the previously established oral dose. To avoid drug cumulation due to absorption from the muscle depots, it is recommended that for the first week back on oral phenytoin, the dose be reduced to half of the original oral dose (one third of the IM dose). Experience for periods greater than one week is lacking and blood level monitoring is recommended. For administration of phenytoin in patients who cannot take oral medication for periods greater than a week, gastric intubation may be considered.
Phenytoin Sodium Injection is indicated for the control of status epilepticus of the grand mal type and prevention and treatment of seizures occurring during neurosurgery.
Phenytoin is contraindicated in patients with a history of hypersensitivity to hydantoin products.
Because of its effect on ventricular automaticity, phenytoin is contraindicated in sinus bradycardia, sino-atrial block, second-and third-degree A-V block, and patients with Adams-Stokes syndrome.
Intravenous administration should not exceed 50 mg per minute in adults.
In neonates, the drug should be administered at a rate not exceeding 1-3 mg/kg/min.
Severe cardiotoxic reactions and fatalities have been reported with atrial and ventricular conduction depression and ventricular fibrillation. Severe complications are most commonly encountered in elderly or gravely ill patients.
Phenytoin should be used with caution in patients with hypotension and severe myocardial insufficiency.
Hypotension usually occurs when the drug is administered rapidly by the intravenous route.
The intramuscular route is not recommended for the treatment of status epilepticus since blood levels of phenytoin in the therapeutic range cannot be readily achieved with doses and methods of administration ordinarily employed.
There have been a number of reports suggesting a relationship between phenytoin and the development of lymphadenopathy (local or generalized) including benign lymph node hyperplasia, pseudolymphoma, lymphoma and Hodgkin's Disease. Although a cause and effect relationship has not been established, the occurrence of lymphadenopathy indicates the need to differentiate such a condition from other types of lymph node pathology. Lymph node involvement may occur with or without symptoms and signs resembling serum sickness, e.g., fever, rash and liver involvement.
In all cases of lymphadenopathy, follow-up observation for an extended period is indicated and every effort should be made to achieve seizure control using alternative antiepileptic drugs.
Acute alcoholic intake may increase phenytoin serum levels while chronic alcoholic use may decrease serum levels.
Usage In Pregnancy
A number of reports suggest an association between the use of antiepileptic drugs by women with epilepsy and a higher incidence of birth defects in children born to these women. Data are more extensive with respect to phenytoin and phenobarbital, but these are also the most commonly prescribed antiepileptic drugs; less systematic or anecdotal reports suggest a possible similar association with the use of all known antiepileptic drugs.
The reports suggesting a higher incidence of birth defects in children of drug-treated epileptic women cannot be regarded as adequate to prove a definite cause and effect relationship. There are intrinsic methodologic problems in obtaining adequate data on drug teratogenicity in humans; genetic factors or the epileptic condition itself may be more important than drug therapy in leading to birth defects. The great majority of mothers on antiepileptic medication deliver normal infants. It is important to note that antiepileptic drugs should not be discontinued in patients in whom the drug is administered to prevent major seizures, because of the strong possibility of precipitating status epilepticus with attendant hypoxia and threat to life. In individual cases where the severity and frequency of the seizure disorder are such that the removal of medication does not pose a serious threat to the patient, discontinuation of the drug may be considered prior to and during pregnancy, although it cannot be said with any confidence that even minor seizures do not pose some hazard to the developing embryo or fetus. The prescribing physician will wish to weigh these considerations in treating or counseling epileptic women of childbearing potential.
In addition to the reports of increased incidence of congenital malformation, such as cleft lip/palate and heart malformations in children of women receiving phenytoin and other antiepileptic drugs, there have more recently been reports of a fetal hydantoin syndrome. This consists of prenatal growth deficiency, microcephaly and mental deficiency in children born to mothers who have received phenytoin, barbiturates, alcohol or trimethadione. However, these features are all interrelated and are frequently associated with intrauterine growth retardation from other causes.
There have been isolated reports of malignancies, including neuroblastoma, in children whose mothers received phenytoin during pregnancy.
An increase in seizure frequency during pregnancy occurs in a high proportion of patients, because of altered phenytoin absorption or metabolism. Periodic measurement of serum phenytoin levels is particularly valuable in the management of a pregnant epileptic patient as a guide to an appropriate adjustment of dosage. However, postpartum restoration of the original dosage will probably be indicated.
Neonatal coagulation defects have been reported within the first 24 hours in babies born to epileptic mothers receiving phenobarbital and/or phenytoin. Vitamin K has been shown to prevent or correct this defect and has been recommended to be given to the mother before delivery and the neonate after birth.
The addition of Phenytoin Sodium Injection to intravenous infusion is not recommended due to lack of solubility and resultant precipitation.
Phenytoin Sodium Injection should be injected slowly (not exceeding 50 mg per minute in adults), directly into a large vein through a large-gauge needle or intravenous catheter. Each injection of intravenous Phenytoin Sodium Injection should be followed by an injection of sterile saline through the same needle or intravenous catheter to avoid local venous irritation due to the alkalinity of the solution. Continuous infusion should be avoided.
Soft tissue irritation and inflammation has occurred at the site of injection with and without extravasation of intravenous phenytoin. Soft tissue irritation may vary from slight tenderness to extensive necrosis, sloughing, and in rare instances has led to amputation. Improper administration including subcutaneous or perivascular injection should be avoided to help prevent the possibility of the above.
Edema, discoloration and pain of the distal limb (described as "purple glove syndrome") have been reported following peripheral intravenous phenytoin sodium injection. This may or may not be associated with extravasation. Although resolution of symptoms may be spontaneous, skin necrosis and limb ischemia have occurred and required such interventions as fasciotomies, skin grafting and amputation. Therefore, Phenytoin Sodium Injection should be administered as described above.
The liver is the site of biotransformation. Patients with impaired liver function, elderly patients, or those who are gravely ill may show early toxicity.
A small percentage of individuals who have been treated with phenytoin have been shown to metabolize the drug slowly.
Slow metabolism may be due to limited enzyme availability and lack of induction; it appears to be genetically determined.
Phenytoin should be discontinued if a skin rash appears (see WARNINGS section regarding drug discontinuation). If the rash is exfoliative, purpuric, or bullous or if lupus erythematosus or Stevens-Johnson syndrome is suspected, use of this drug should not be resumed and alternative therapy should be considered. (See ADVERSE REACTIONS.) If the rash is of a milder type (measles-like or scarlatiniform), therapy may be resumed after the rash has completely disappeared. If the rash recurs upon reinstitution of therapy, further phenytoin medication is contraindicated.
Hyperglycemia, resulting from the drug's inhibitory effects on insulin release, has been reported. Phenytoin may also raise the serum glucose level in diabetic patients.
Phenytoin is not indicated for seizures due to hypoglycemic or other metabolic causes. Appropriate diagnostic procedures should be performed as indicated.
Phenytoin is not effective for absence (petit mal) seizures. If tonic-clonic (grand mal) and absence (petit mal) seizures are present, combined drug therapy is needed.
Serum levels of phenytoin sustained above the optimal range may produce confusional states referred to as "delirium," "psychosis," or "encephalopathy," or rarely irreversible cerebellar dysfunction. Accordingly, at the first sign of acute toxicity, plasma levels are recommended. Dose reduction of phenytoin therapy is indicated if plasma levels are excessive; if symptoms persist, termination is recommended. (See WARNINGS.)
Laboratory Tests
Phenytoin serum level determinations may be necessary to achieve optimal dosage adjustments.
Drug Interactions
There are many drugs which may increase or decrease phenytoin levels or which phenytoin may affect. The most commonly occurring drug interactions are listed below:
Serum level determinations are especially helpful when possible drug interactions are suspected.
Drug/Laboratory Test Interactions
Phenytoin may cause decreased serum levels of protein-bound iodine (PBI). It may also produce lower than normal values for dexamethasone or metyrapone tests. Phenytoin may cause increased serum levels of glucose, alkaline phosphatase, and gamma glutamyl transpeptidase (GGT).
The most notable signs of toxicity associated with the intravenous use of this drug are cardiovascular collapse and/or central nervous system depression. Hypotension does occur when the drug is administered rapidly by the intravenous route.
The rate of administration is very important; it should not exceed 50 mg per minute in adults, and 1-3 mg/kg/min in neonates. At this rate, toxicity should be minimized.
Severe cardiotoxic reactions and fatalities have been reported with atrial and ventricular conduction depression and ventricular fibrillation. Severe complications are most commonly encountered in elderly or gravely ill patients.
Central Nervous System
The most common manifestations encountered with phenytoin therapy are referable to this system and are usually dose-related. These include nystagmus, ataxia, slurred speech, decreased coordination and mental confusion. Dizziness, insomnia, transient nervousness, motor twitchings and headaches have also been observed. There have also been rare reports of phenytoin induced dyskinesias, including chorea, dystonia, tremor and asterixis, similar to those induced by phenothiazine and other neuroleptic drugs.
A predominantly sensory peripheral polyneuropathy has been observed in patients receiving long-term phenytoin therapy.
Gastrointestinal System
Nausea, vomiting and constipation.
Integumentary System
Dermatological manifestations sometimes accompanied by fever have included scarlatiniform or morbilliform rashes. A morbilliform rash (measles-like) is the most common; other types of dermatitis are seen more rarely. Other more serious forms which may be fatal have included bullous, exfoliative or purpuric dermatitis, lupus erythematosus, Stevens-Johnson syndrome, and toxic epidermal necrolysis (see PRECAUTIONS).
Hemopoietic System
Hemopoietic complications, some fatal, have occasionally been reported in association with administration of phenytoin. These have included thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis and pancytopenia with or without bone marrow suppression. While macrocytosis and megaloblastic anemia have occurred, these conditions usually respond to folic acid therapy. Lymphadenopathy including benign lymph node hyperplasia, pseudolymphoma, lymphoma and Hodgkin's Disease have been reported (see WARNINGS).
Connective Tissue System
Coarsening of the facial features, enlargement of the lips, gingival hyperplasia, hypertrichosis and Peyronie's Disease.
Injection Site
Local irritation, inflammation, tenderness, necrosis and sloughing have been reported with or without extravasation of intravenous phenytoin.
Systemic lupus erythematosus, periarteritis nodosa, toxic hepatitis, liver damage, immunoglobulin abnormalities and purple glove syndrome may occur. (See PRECAUTIONS.)
The lethal dose in children is not known. The lethal dose in adults is estimated to be 2 to 5 grams. The initial symptoms are nystagmus, ataxia and dysarthria. Other signs are tremor, hyperflexia, lethargy, slurred speech, nausea, vomiting. The patient may become comatose and hypertensive. Death is due to respiratory and circulatory depression.
There are marked variations among individuals with respect to phenytoin plasma levels where toxicity may occur. Nystagmus, on lateral gaze, usually appears at 20 mcg/mL, ataxia at 30 mcg/mL, dysarthria and lethargy appear when the plasma concentration is over 40 mcg/mL, but as high a concentration as 50 mcg/mL has been reported without evidence of toxicity. As much as 25 times the therapeutic dose has been taken to result in a serum concentration over 100 mcg/mL with complete recovery.
Treatment is nonspecific since there is no known antidote.
The adequacy of the respiratory and circulatory systems should be carefully observed and appropriate supportive measures employed. Hemodialysis can be considered since phenytoin is not completely bound to plasma proteins. Total exchange transfusion has been used in the treatment of severe intoxication in pediatric patients.
In acute overdosage, the possibility of other CNS depressants, including alcohol, should be borne in mind.
The addition of Phenytoin Sodium Injection to intravenous infusion is not recommended due to the lack of solubility and resultant precipitation.
Not to exceed 50 mg per minute, intravenously in adults, and not exceeding 1-3 mg/kg/min in neonates. There is a relatively small margin between full therapeutic effect and minimally toxic doses of this drug.
The solution is suitable for use as long as it remains free of haziness and precipitate. Upon refrigeration or freezing, a precipitate might form; this will dissolve again after the solution is allowed to stand at room temperature. The product is still suitable for use. Only a clear solution should be used. A faint yellow coloration may develop; however, this has no effect on the potency of the solution.
In the treatment of status epilepticus, the intravenous route is preferred because of the delay in absorption of phenytoin when administered intramuscularly.
Serum concentrations should be monitored and care should be taken when switching a patient from the sodium salt to the free acid form.
Phenytoin Sodium Injection is formulated with the sodium salt of phenytoin. Because there is approximately an 8% increase in drug content with the free acid form over that of the sodium salt, dosage adjustments and serum level monitoring may be necessary when switching from a product formulated with the sodium salt and vice versa.
Status Epilepticus
In adults, a loading dose of 10 to 15 mg/kg should be administered slowly intravenously, at a rate not exceeding 50 mg per minute (this will require approximately 20 minutes in a 70 kg patient). The loading dose should be followed by maintenance doses of 100 mg orally or intravenously every 6-8 hours.
Recent work in neonates and pediatric patients has shown that absorption of phenytoin is unreliable after oral administration, but a loading dose of 15-20 mg/kg of phenytoin intravenously will usually produce plasma concentrations of phenytoin within the generally accepted therapeutic range (10-20 mcg/mL). The drug should be injected slowly intravenously at a rate not exceeding 1-3 mg/kg/min.
Phenytoin Sodium Injection should be injected slowly and directly into a large vein through a large-gauge needle or intravenous catheter. Each injection of intravenous phenytoin should be followed by an injection of sterile saline through the same needle or catheter to avoid local venous irritation due to alkalinity of the solution. Continuous infusion should be avoided; the addition of Phenytoin Sodium Injection to intravenous infusion fluids is not recommended because of the likelihood of precipitation.
Continuous monitoring of the electrocardiogram and blood pressure is essential. The patient should be observed for signs of respiratory depression. Determination of phenytoin plasma levels is advised when using phenytoin in the management of status epilepticus and in the subsequent establishment of maintenance dosage.
Other measures, including concomitant administration of an intravenous benzodiazepine such as diazepam, or an intravenous short-acting barbiturate, will usually be necessary for rapid control of seizures because of the required slow rate of administration of phenytoin.
If administration of Phenytoin Sodium Injection does not terminate seizures, the use of other anticonvulsants, intravenous barbiturates, general anesthesia and other appropriate measures should be considered.
Intramuscular administration should not be used in the treatment of status epilepticus because the attainment of peak plasma levels may require up to 24 hours.
Prophylactic dosage—100 to 200 mg (2 to 4 mL) intramuscularly at approximately 4-hour intervals during surgery and continued during the postoperative period.
When intramuscular administration is required for a patient previously stabilized orally, compensating dosage adjustments are necessary to maintain therapeutic plasma levels. An intramuscular dose 50% greater than the oral dose is necessary to maintain these levels. When returned to oral administration, the dose should be reduced by 50% of the original oral dose for one week to prevent excessive plasma levels due to sustained release from intramuscular tissue sites.
If the patient requires more than a week of IM phenytoin, alternative routes should be explored, such as gastric intubation. For time periods less than one week, the patient shifted back from IM administration should receive one half the original oral dose for the same period of time the patient received IM phenytoin. Monitoring plasma levels would help prevent a fall into the subtherapeutic range. Serum blood level determinations are especially helpful when possible drug interactions are suspected.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
Phenytoin Sodium Injection, USP, 50 mg/mL is supplied in the following:
Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.]
Do not freeze.
To prevent needle-stick injuries, needles should not be recapped, purposely bent, or broken by hand.
Revised: November, 2010
Printed in USA EN-2698
Hospira, Inc., Lake Forest, IL 60045 USA
Revised: 04/2011 Hospira, Inc.
Reproduced with permission of U.S. National Library of Medicine
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text:
A collection of scholarly works about individual liberty and free markets. A project of Liberty Fund, Inc.
1698 - 1748
Historical Period:
The 18th Century
George Turnbull (1698-1748) was a lesser-known contemporary of Hutcheson, Hume, and Smith. He taught at Marischal College, Aberdeen, then became a traveling tutor, and ended his career as an Anglican clergyman, first as a chaplain to the Prince of Wales, then as a minister in Ireland. Turnbull was the first member of the Scottish Enlightenment to provide a formal treatise on the theory and practice of education.


text:
Demi Moore is asking for spousal support and legal fees from her estranged husband Ashton Kutcher following the breakdown of their six-year marriage.
The actress has been separated from Kutcher since November, 2011 and he took the first step towards divorce by filing papers in Los Angeles Superior Court in December.
The actress, who was previously married to Bruce Willis, finally responded with her own documents on Thursday, citing "irreconcilable differences" for the split, but she is preparing to fight for a share of Kutcher's fortune, which was boosted last year by the reported $24 million he earned as Charlie Sheen's replacement on hit sitcom "Two and a Half Men."
Kutcher had not asked for spousal support and did not ask a judge to deny Moore financial aid.
Kutcher, 35, has since moved on to romance his former "That '70s Show" co-star Mila Kunis, while 50-year-old Moore was recently linked to director Julian Schnabel's art collector son Vito.


text:
Presidential messages to have their own distinctive ring tone
Paul Joseph Watson
Monday, June 25, 2012
Not only does the Department of Homeland Security's new emergency alert system force cellphone users to receive text messages directly from President Obama, it also "follows" the user wherever they go, according to newly released details of the program.
As we reported last week, Apple's eagerly awaited iOS 6 update for iPhones and iPads will feature the alerts, along with updates of other operating systems. All new cell phones will be required to comply with the PLAN program (Personal Localized Alerting Network), which will broadcast emergency alert messages directly to Americans' cell phones, either through chips directly embedded in new phones or with software upgrades for older models.
According to Todd Krause, the weather-warning coordinator at the National Weather Service's Chanhassen office, the WEA alert system tracks cellphone users wherever they go in order to deliver region-specific warnings.
"What the system does is actually follow you around wherever you are going," based on users' proximity to cellular towers," Krause told TwinCities.com.
The fact that the system will empower Big Sis to "follow" cellphone users around the country has been kept under wraps until now, and is sure to prompt a firestorm of criticism from privacy advocates on both the left and right.
Since almost everyone who is active in public life now has a cellphone and carries it at all times, such a tracking system is barely much different from having an implanted microchip that constantly beams out your location. Indeed,newer microchips for cellphones can now pinpoint a user's location down to just a few centimeters.
While users can opt out of receiving extreme weather alerts and Amber alerts, messages sent from the president will be mandatory, and will even have their own distinctive ring tone.
"The new 90-character-or-less alerts resemble regular texts but are a different form of messaging that includes a distinctive ring tone and also makes a device vibrate," states the report, adding that the messages will be able to circumvent potential cellular disruption that would prevent ordinary messages from getting through.
- A d v e r t i s e m e n t
- {openx:74}
"If the United States faces a nationwide crisis of some sort, the president can transmit a mobile alert that pops up automatically on phones across the country," adds the article, noting that cellphone users will not have to fiddle around with apps to receive the alerts.
Confirming earlier reports, the story notes that users, "can't block presidential alerts."
As we have previously highlighted, early tests of the emergency alert system in New Jersey caused panic after Verizon customers received text messages warning them that a "civil emergency" was in progress and to "take shelter," prompting alarmed citizens to flood 911 lines with anxious calls.
Verizon Wireless later apologized to its customers for causing alarm, admitting that the confusion was caused by a "test" of the PLAN emergency alert system.
As we have documented, the PLAN program is part of the wider move on behalf of Homeland Security to create a public environment dominated by a pervasive sense of fear and paranoia, a context in which the safe exercise of constitutional freedoms doesn't normally thrive.
Concerns have also been raised at the potential for the federal government or the Obama presidential campaign to use the messages to create unwarranted fear for political purposes.
The emergency alerts are eventually designed to be incorporated into the Intellistreets system which turns all street lights into surveillance hubs that can record conversations and broadcast messages.
Paul Joseph Watson is the editor and writer for Prison Planet.com. He is the author of Order Out Of Chaos. Watson is also a regular fill-in host for The Alex Jones Show and Infowars Nightly News.
The Emergency Election Sale is now live! Get 30% to 60% off our most popular products today!


text:
Contribute to ReadWriteThink / RSS / FAQs / Site Demonstrations / Contact Us / About Us
Find the latest in professional publications, learn new techniques and strategies, and find out how you can connect with other literacy professionals.
Home › Professional Development › Professional Library
Adolescents and Digital Literacies: Learning Alongside Our Students
by Sara Kajder
|9 – 12
|January 2010
Purchase this book now from the NCTE Online Store
Become an NCTE member and get a discount on this book
This book isn't about technology. It's about the teaching practices that technology enables. Instead of focusing on where to point and click, this book addresses the ways in which teachers and students work together to navigate continuous change and what it means to read, write, view, listen, and communicate in the twenty-first century.
Related Resources
Grades 6 – 8 | Lesson Plan | Standard Lesson
Building Vocabulary: Making Multigenre Glossaries Based on Student Inquiry
Students choose unfamiliar words from their reading and create a multigenre, multimodal glossary of terms.
Grades 9 – 12 | Lesson Plan | Unit
Having My Say: A Multigenre Autobiography Project
Students compose a multigenre paper, modeled after the Delany sister's autobiography, Having Our Say, that includes the autobiographical narrative essay as well as an informational nonfiction piece.
Grades 9 – 12 | Lesson Plan | Unit
It's My Life: Multimodal Autobiography Project
Students express themselves verbally, visually, and musically by creating multimodal autobiographies, exchanging ideas with other students and sharing important events in their lives through PowerPoint presentations.
Grades 3 – 5 | Lesson Plan | Unit
Zines for Kids: Multigenre Texts About Media Icons
Special edition! Students use ReadWriteThink tools to create magazines about prominent figures using a variety of writing genres and styles.
Grades 9 – 12 | Lesson Plan | Unit
Designing Museum Exhibits for The Grapes of Wrath: A Multigenre Project
Using The Grapes of Wrath as a backdrop, students conduct research on issues that the novel addresses, publishing their findings in a multigenre museum exhibit.
Grades 9 – 12 | Lesson Plan | Unit
Short Story Fair: Responding to Short Stories in Multiple Media and Genres
In this activity, students read short stories and create presentations in multiple media to share in a Short Story Fair. At the fair, students explore and respond to the displays.
Grades 6 – 8 | Lesson Plan | Standard Lesson
Reading and Analyzing Multigenre Texts
Students develop a definition of multigenre texts by exploring multigenre picture books. They brainstorm what it takes to read these texts successfully and discuss strategies needed to comprehend the texts.


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Conservation through Education
The Cougar Mountain Zoo Volunteer Program
offers a broad variety of unique experiences for qualified Volunteers.
There are many reasons why you should
become a Volunteer and share the joys this fulfilling involvement offers.
Volunteering at the Zoo offers a chance
to enrich your life through a better understanding of nature and the earth's vanishing
As a Volunteer you get to know and develop
a special relationship with others who share a common interest.
You will gain valuable experience, training,
interact with some of the most unique and endangered animals, play an important
role in the conservation of wildlife and promote the cause of the natural world.
As a Volunteer you will also be the recipient
of the appreciation and recognition one deserves for volunteering time and talent
to a noble cause.
Click here to download docent/volunteer application.
Education (Docent)
One of the primary roles of a Docent is
to serve in educational and interpretive capacities.
Docents play a role as roving Interpreters, Tour Guides, Animal Behavior
Observers, Outreach Specialists, Museum/Gallery/Gift Shop Attendants and may also
be working with live Zoo Animals in the course of Zoo Educational Programs.
Fundraising (Docent)
Volunteers assist the Zoo in a range of
fundraising activities and help promote Zoo Programs such as Membership, Pave the
Way Program, Wildlife Tracks Library Expansion, Sponsorships, Events and other functions.
Volunteers with construction and maintenance
skills may assist in many areas throughout the year.
Volunteers with green thumbs assist with
planting, cultivating flowers and maintaining shrubs and trees.
Gardeners also research the viability of introducing new flora into animal
habitats and general landscaping throughout the Zoo.
Volunteers with administrative skills
may assist in Zoo and Society offices fulfilling various roles.
Computer skills are not required but helpful.
Animal Care (Keeper Aide)
There are no Volunteer openings in this category.
Volunteers with the required aptitude
may work towards becoming Volunteer Aides assisting Zoo Keepers in supportive roles
(minimum age 21).
How to Do It
Our Volunteer Program requires special
people with a sincere desire and commitment to the Zoo's philosophy of education,
conservation and a quality life for our Zoo Animals.
To become a Volunteer one must be at least
eighteen years old and serious about making a time commitment.
Previous experience is not necessary.
The first step in becoming a Volunteer
is to download, fill out and turn in the
volunteer application. Once this has been reviewed, you will be contacted to schedule an introductory meeting.


text:
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The United Nations Decade on Biodiversity was officially launched on December 17 by the UN Secretary-General. The General Assembly previously declared the period 2011-2020 as United Nations Decade on Biodiversity (A/RES/65/161) to promote the implementation of a strategic plan on biodiversity and its overall vision of living in harmony with nature.
The main goal is to mainstream biodiversity at different levels. Throughout the Decade, governments are encouraged to develop, implement and communicate the results of national strategies for implementation of the Strategic Plan for Biodiversity.
UN Pulse entries are now also posted on Tumblr.
The Brussels based United Nations Regional Information Centre for Western Europe - UNRIC provides information on UN activities to the countries of the region. It also provides liaison with institutions of the European Union in the field of information. Its outreach activities extend to all segments of society and joint campaigns, projects and events are organized with partners including the EU, governments, the media, NGOs, schools and local authorities.
United Nations Regional Information Centre for Western Europe (UNRIC Brussels)
Residence Palace, Rue de la Loi/Wetstraat 155, Block C2,7th and 8th floor, Brussels 1040, Belgium
Tel.: +32 2 788 8484 / Fax: 32 2 788 8485


text:
A 42 story res. building at 566'!Originally Posted by sfenn1117
Those must be some crazy high cielings.
Looks like demolition is almost complete:
This site is ridiculously small for such a tall building. I'm all for thin, tall towers, but this is almost too small.
A 42 story res. building at 566'!Originally Posted by sfenn1117
Those must be some crazy high cielings.
DOB records show that ALL the construction-related applications for this New Building have so far been DISAPPROVED
The Schedule A filed with that ^ Application shows that Residential Units will start on the 3rd Floor. Floors 3 - 40 will have 3 Residential Units per Floor. Floor 41 will have 2 Units; Floor 42 will have 1 Unit.
Plans for the Foundation were filed on 7.12.06 and have been "assigned to Plan Examiner" -- but have not yet been Approved.
The ONLY Application so far Approved is for DEMO.
The Big Apple's Most Active Thoroughfare
August 17, 2006
URL: http://www.nysun.com/article/38112
<IMGSRC="http://oasis.nysun.com/oasis/oasisi.php?s=7&w=300&h=250&t=_blank"WIDTH=300 HEIGHT=250 BORDER=0><IMGSRC="http://oasis.nysun.com/oasis/oasisi.php?s=6&w=300&h=250&t=_blank"WIDTH=300 HEIGHT=250 BORDER=0>
Just west of the heart of Times Square is "an avenue of commerce that rivals all north-south thoroughfares in the Big Apple," the director at Eastern Consolidated Properties, Alan Miller, said.
"As the Times Square area developed into a magnet for large law firms, me<IMGSRC="http://oasis.nysun.com/oasis/oasisi.php?s=7&w=300&h=250&t=_blank"WIDTH=300 HEIGHT=250 BORDER=0> <IMGSRC="http://oasis.nysun.com/oasis/oasisi.php?s=6&w=300&h=250&t=_blank"WIDTH=300 HEIGHT=250 BORDER=0>
Just west of the heart of Times Square is "an avenue of commerce that rivals all north-south thoroughfares in the Big Apple," the director at Eastern Consolidated Properties, Alan Miller, said.
"As the Times Square area developed into a magnet for large law firmsdia, and financial services firms, eyes turned west to find opportunities for development of walk-to-work luxury housing", the senior director of sales at Massey Knakal Realty Services, Christoffer Broadhead, said. "Eighth Avenue has the right zoning and location to meet this need."
McSam Hotel Group LLC is one company taking advantage of this proximity to Times Square and a robust hospitality market, building no less than 1,300 hotel rooms in seven new groundup developments, all on one block. Starting at 585 Eighth Ave., Sam Chang, the president of McSam Hotel, one of the nation's largest builders of new hotels, is transforming the once dreary block on West 39th Street between Eighth and Ninth avenues into a hotel destination. It is an area that has a tremendous need for affordable hotel rooms.
Meanwhile, in June the new headquarters of the New YorkTimes was declared "topped out," with the installation of the final steel beam.The 52-story tower sits on the east side of Eighth Avenue between 40th and 41st streets, across from the Port Authority Bus Terminal. The site represents the westward expansion of Midtown and the most significant construction along Eighth Avenue since the construction of One Worldwide Plaza in 1989.
The tower, which will be the third tallest skyscraper in New York City, is a joint venture of the New York Times Company, Forest City Ratner Companies, and ING Real Estate.The building will have 1.54 million square feet of gross space.
The New York Times Company will occupy about 800,000 square feet on the second through the 28th floors, with Forest City Ratner and ING Real Estate owning about 700,000 square feet on floors 29 through 52, as well as 24,000 square feet of street-level retail space. In June, Forest City announced it had entered into an agreement to acquire ING Real Estate's interest in the tower.
Prior to the construction of the Times tower, the most significant construction on Eighth Avenue was the development of Worldwide Plaza.The complex occupies an entire city block bounded by Eighth and Ninth avenues and 49th and 50th streets on the site of the third Madison Square Garden. The office tower, One Worldwide Plaza, is a 47-story, 1.5 millionsquare-foot office building developed by William Zecdkendorf Jr. The residential component, 455 apartments, is located in a 38-story tower and sixstory low-rises.
There are also other developments in the works on Eighth Avenue.
SJP Properties last month purchased the eastern block front site on the avenue between 41st and 42nd streets from Howard and Edward Milstein. It paid $306 million for the site. On Monday, SJP announced plans to construct a 40-story, 1 million-squarefoot office tower. It would buy additional development rights for $23.2 million. The project would be a development of SJP and the Prudential Insurance Company. It was the last remaining parcel in the Times Square redevelopment district.
On the northwest corner of West 42nd Street and Eighth Avenue, a Duane Reade is situated on a small parcel that was purchased by a group led by Jeff Sutton and Joe Cayre. It was purchased from HSBC Bank for about $30 million.
On the southwest corner of West 44th Street and Eighth Avenue, Steve Witkoff and a minority partner, Harwood Properties, are planning to construct a 250,000-square-foot residential condominium with about 256 units at 693-699 Eighth Ave. and 307-321 W. 43rd St. A few years ago, Mr. Witkoff purchased the majority stake in Harwood's parking garage at the site for about $26 million.
Across from the Milford Plaza Hotel is a potential development site owned by the Hotel Employees Union. The real estate industry has been keeping a close watch as to when the union plans to take advantage of this west side block front between 44th and 45th streets, where another luxury mixeduse building will rise out of the ground one day soon.
Industry leaders expect Related Companies and Boston Properties to acquire a parking lot owned by Champion Parking with frontage on the east side of Eighth Avenue on West 45th Street. A major residential tower is expected to rise on the site. The Related Companies recently acquired a site at 259-263 W. 45th St., adjacent to the development site, which would be used as well. Air rights would be purchased from local theaters.
At the northeast corner of 46th Street and Eighth Avenue, with addresses at 301-307 W. 46th St. and 733-763 Eighth Ave., SJP is developing a 42-story condominium tower with 250 units on the former site of McHale's pub. In order to develop the site, it also acquired about 140,000 square feet of air rights from the Brooks Atkins and Al Hirschfield theaters. SJP is developing a condominium tower at 45 Park Ave. on the former site of the Sheraton Russell Hotel.
Recently, a development site at the northwest corner of West 46th Street and Eighth Avenue was sold to Jim Money of Tribeach Holdings, a small, Irish-backed development company that plans to construct a new building.
Just south of this are two properties owned by investor Lloyd Goldman the site of the China Club on the southeast corner of West 47th Street and a vacant site on the northwest corner of West 47th Street. Industry leaders expect the sites to be rented to a bank until the ownership decides to develop or sell them.
A 40-story, 119-unit luxury condominium tower will rise on Eighth Avenue between 47th and 48th streets. The site contains 130,000 square feet, and when completed the building will have 92,000 square feet of residential and 1,663 square feet of retail space. The building will be located on lots at 785 Eighth Ave. and 306 W. 48th St.The building is a development of Ulo Barad, David Scharf's, Espanade Capital LLC, and Jay Eisenstadt, as well as an entity consisting of partners of Navillus Corporation.
"The Scharf site shows the extent to which builders will innovate to meet the thirst for development properties on Eighth Avenue," Mr. Broadhead said.
In the first quarter of 2007, El-Ad Properties expects the first purchasers to move into its newest luxury condominium tower at 310 W. 52nd St. The Link, a 215-unit tower, is straddling a site between Midtown and the special Clinton district, where building heights are limited to 70 feet or seven stories. It features a 471-foot high-rise and an adjoining mid-rise to the west to satisfy the dual zoning requirements.
"The Link is a text book example of the benefits of developing on Eighth Avenue as opposed to developing in the special Clinton district," which starts west of Eighth Avenue, Mr. Broadhead said.
The development began when Hampshire Hotel purchased the twostory Studio Instrumental rental building in May 2004 for $9 million, or $125 a developable foot. The first 50 feet of the building are not located in the height-restricted zone, while the remaining 50 feet are in the special Clinton district. In September 2004, Hampshire Hotel sold the site, plus approximately 167,000 square feet of air rights, for $43 million, or $181 a developable foot, to El-Ad.
Industry leaders expect a joint venture of Gary Barnett, Extell Investment, and Westbrook Partners to sell a residential rental building, the 264-unit Encore apartment building at 301 W. 53rd St., aka 891 Eighth Ave. The joint venture purchased the 25-story building about two years ago for $130 million from Ruben Schron.
This summer, employees of the Heart Corporation moved into the Hearst Tower, a 46-story, 856,000-square-foot office tower.The new building was built on the six-story structure commission by William Randolph Hearst to house the 12 magazines he owned in 1927, when construction began. It was completed in 1928, at a cost of $2 million. The tower, located at 959 Eighth Ave., between 56th and 56th streets, originally was named the International Magazine Building.The building was designated as a landmark site by the Landmarks Preservation Commission in 1988.
Across the street, on Eighth Avenue between 54th and 55th streets, the Hearst Corporation had owned a large site for more than 20 years. Early this year, Robert Gladstone of Madison Equities paid about $170 million for the site. The developer also purchased air rights from the Al Hirschfield and St. James theaters. It plans to build a luxury high-rise and hotel tower, which is rumored to include a Hyatt Hotel.
On September 15, the sales office will open at the Sheffield, the 50-story mixed-use residential tower at 322 West 57th St. The partnership of Swig Equities, Yair Levy, and Serge Hoyda paid $418 million for the property in April 2005.
Later this year, Thompson Hotels, owned by the Pomeranc Family and its investors Rosen Partners, will open 6 Columbus, a 100-room hotel on the former site of the West Park Hotel at 6 Columbus Ave. The joint venture acquired the site a few years ago, and is in the process of adding three floors and doing a gut renovation of the former 90-room hotel directly across from the Time Warner Center.
I have to concur with Alan Miller when he says,"Eighth Avenue, once the downtrodden thoroughfare acting as the step-brother of Times Square's most famous boulevard, Broadway, has blossomed into what can certainly be called New York City's most exciting and active passageway."
New Approvals at DOB regarding foundation work have come through since I posted that last info:
104480508 01A2001P APPROVED 07/26/2006Filing herewith foundation for the errection of a new building. No change
104480508 02A2P APPROVED 07/26/2006Filing herewith for underpinning/ shoring for the excavation of a newHowever it seems that all the Applications for the actual NEW BUILDING continue to be DISAPPROVED:
I like Latitude's blue neon sign next door. Can you still put up a new sign like that, or is that one grandfathered?
In fact the LATITUDE signs are fairly recent additions (just look retro).
8th still has a decent number of retro/neon signage. Times Square, for the most part, is LED.
Mefears it is soon to be wiped too clean ...
Can someone please do something with that Bennigans already. It's hurtin!
This "T"-shaped lot has been completely cleared -- except for one very LARGE tree which sits at the intersection of the two lots -- you can see the tree from the gate on 48th St.
But you had better hurry ...
A construction worker on the site today said that digging of the foundation is to start on September 18.
However DOB shows that the FIre Plan for the New Building was DISAPPROVED on 9.05.2006


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I'm not sure why it's doing this but I cannot purchase anything on Wincustomize it doesn't mateer what the item is I can't buy it. any help
I have forwarded your report to the Stardock support team for their review and recommendations.
Please keep an eye on this thread for any updates.
We really do appreciate your feedback, thanks.
AzDudeStardock Community Assistant
AzDude, thanks for the help I will key an eye on this thread
Sorry to hear you are having issues.
We will need more info to help you .
1st , try a different browser or two incase one browser is blocking you /
2 nd. What version of Windows are you running
3 is your Stardock Account up to date
4 What apps do you want to buy ? you will need the right version for your version of Windows .
Report back here with this info then we can proceed with help, Thanks .
1st - google chrome no difference
2nd - windows 10 home
3rd - yes
4th - windowblinds mostly
So what browser do you use ?
What version of windows 10 home try ( type in winver in run )
Is you problem buying the WindowBlinds App or buying Master WindowBlinds Skins from the Masters ?
Browser - Microsoft Edge and Google Chrome
Version of windows 10, 1809
it happens at the time of purchase right at the end
That's what i need to know purchase what the WB app
or a master skin ( just one having a problem or several )
Master skins and it isn't just one WB but every master skin
Are you getting an error? Please be more specific on what is happening.
I am not getting a error but what happens at the end of my purchase when you would purchase the WB a box shows up on the screen saying "processing" it stays there until it times out and you can try it again, sure hope this fixes the problem
will do
I'm not saying that it's the solution, but are you by any chance using a pop-up blocker or an ad-blocker? That might be what's preventing a purchase from some web stores.
Try opening Chrome in an incognito window:
And trying to purchase under it.
----------------Sean DrohanStardock Customer Service Manager
Also, are you logged on?
And, another thing to try, click on the "Is this a corporate or business order?" option and verify your address (or enter it if you are not logged on ).
There are many great features available to you once you register, including:
Sign in or Create Account


text:
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