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Business Story Telling - How to Engage people
"• Identify how Storytelling is an impactful communication tool in Today's Business for high stake communication • Dramatize your storytelling to connect with emotions of your audience • Enhance impact with memorable anecdotes and parables • Use personal stories that creatively deliver key messages and takeaways • Demonstrate storytelling skills that make an impact and prompt action in diverse situations"
Ce que vous apprendrez
"1. Define your audience and their needs, goals, and wants 2.Use proven structures to build influence at workplace by leveraging stories 3. Use the secret to storytelling: The Magic Formula 4. Use the power of simplicity and human connect to influence stakeholders"
Pourquoi vous voulez l'apprendre
"In today's professional environment we have very little time to convey our message impactfully to our audience as the attention spans are dwindling. Storytelling is a time-tested but rarely used skill that prepares us to delivery our message impactfully and gets people to see your intentions and values without any bias and they are motivated to take action recommended by you."
Comment cela va vous aider
As Leaders, Managers and Individual contributors very often we have to get involved in high stake conversations that can impact both our personal credibility as well as the business outcomes. This could be a Sales Meeting, a Business Review, an Appraisal Discussion, a Proposal for Change, A Disagreement etc.
Dates du prochain cours
Delhi, Delhi 122003
Mumbai, Maharashtra 400001
Bangalore, Karnataka 560 025


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No brie boycott: French goods still moving locally
With the anti-French sentiment that's been sweeping the nation since U.N. talks broke down, local vendors of French goods have been on heightened alert would Charlottesvillians swap camembert for Kraft?
The answer, it seems, is no.
Though the mayor of Charlottesville's French sister city, Besancon, cancelled a planned April visit to this country because of global tension, locals still favor fromage, with Mayor Blake Caravati leading the charge.
"I'm still eating stinky French Cheese and will continue eating stinky French cheese," Caravati told the Progress earlier this week.
Suzannah Kerr, manager of gourmet food emporium Feast! in the Main Street Market, says a few customers have asked if other people have stopped eating French cheese, but she says her store hasn't seen a decline in sales.
Jose DeBrito, French-born owner of Ciboulette (French for chive), also in the Main Street Market, says, "I have a feeling that since the war has started, business is a little bit slower." Fortunately, he explains, he has a "core of Francophile" customers.
One tourist, DeBrito says, realized that he was in a French-owned establishment. "I'm in the wrong place," DeBrito recalls the man saying as he retreated toward the street.
When faced with recent inquiries regarding his motherland, DeBrito says his answer is simple. "I don't do politics," he laughs. "I do local business."
But Robert Harllee, owner of the Market Street Wineshop, says that while he hasn't seen French wine sales decline ("This is Charlottesville, after all") he has a quick and harsh– response ready for someone with an anti-French attitude.
"The whole 'Freedom fries' thing is ludicrous," Harllee says. "I would just ask, 'Have you stopped putting Iraqi oil in your SUV?'"

subset: commoncrawl


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NB. Since all of this kicked off The Moff has issued a kind of 'get your kids of my lawn' response and private Eye basically suggested that the BBC leaked the news in an effort to undermine Moffat, with whom it is quickly losing patience. Make of that what you will.
A new Doctor Who film? Those fans who might conceivably have watched The Twin Dilemma when originally broadcast may recall a few other Doctor Who films supposedly in the pipeline through the decades.
Tom's Doctor Who meets Scratchman, written by himself and Ian Marter, starring Vincent Price and funded by crumpled £1 notes mailed to Tom from keen fans.
The ones suggested in the very early 90s that would star Donald Sutherland and feature a rapping TARDIS perhaps (I defaced the images of Sutherland in anger) or the more recent Tennant-and-Piper rumours.
Then there was the TVM. Well, they got McGann pretty much right, but the rest was an absolute mess - a more fitting example you could not find of what happens when people who don't understand or care for Doctor Who make Doctor Who.
Today has brought with it the news that Harry Potter director David Yates will helm a new Hollywood film featuring a strange character called Doctor Who (never heard of him) that will reboot the series and stick two fingers up at 50 years of canon.
Quite why these rumours have come to light again - about two years after they were first mooted and repeated today with historic quotes - is not clear. Are BBC Worldwide trying to kickstart the project? Has a bored hack in search of an article dug up an old story? Or has someone sniffed that something is actually happening on this front?
We'll wait and see. For now let's look at the claims Yates made about his new film. In a move that could not have alienated the show's fanbase more if he's threatened to cast Vin Diesel, Yates claims that the film will be "starting from scratch".
Why on Earth would you do that? The show has the most malleable format in the genre, perhaps all TV. You can change the lead cast without ditching anything. This is something that has happened innumerable times over the show's history.
If Yates wants a good example of how to kick off a new series - or new interpretation - he need only look to Rose, a terrible episode but a great example of kickstarting something new without abandoning all the good stuff.
It's an important reminder that we've had people at the helm who cared about the show - we know that RTD kiboshed stuff like a female Doctor, a Young Doctor Who series on CBBC and more; and that even Tennant was very protective of what the show did and didn't do.
It's impossible to image Moffat taking the show into taboo territory too. We've been lucky that since the reboot - and in the good old days - we had people who looked after the show as best they could.
Unfortunately, Worldwide is a financial entity and must surely be scenting hard cash and, conceivably, a billion-quid money-spinner like Lord of the Rings or Harry Potter over a multi-film series that would make the TV show look like A Fix With Sontarans in comparison.
That's presumably the thinking behind recruiting a director with no apparent understanding of Doctor Who whose looking to recruit a writer with no apparent understanding of Doctor Who.
Yates pays tribute to Davies and Moffat's visions - and in the same breath announces that he's going to trash it all. Where's the logic to that?
He also says Doctor Who "needs quite a radical transformation to take it into a bigger arena". Does it? Isn't the exact point of the show - its appeal and its essence and its very artron energy - that it's a quaint little British show? Certainly it does epic storylines and its format and tone is elastic but it's always recognisably the same.
RTD and Moff clearly understand this and fandom has largely taken to their series. Perhaps it didn't need older fans, but the likes of the two show-runners are fans after all.
The show doesn't necessarily need a fan to take it to the big screen - or a Brit. But I feel sure that it would be a better product for it - and we have two people who can wield an enormous amount of power in the TV and media world, not to mention people like Neil Gaiman, Stephen Fry and Mark Gatiss who are steeped in the show and are professionals in their own right.
Alas, if what we read is to be believed then Yates directing makes perfect sense in the eyes of BBC Worldwide. They won't give two flying figs if the Doctor carries a gun, shags a busty American and has a time capsule voiced by Mos Def (actually, I like Mos Def, that could work) if it brings in the bucks.
What would this do for the TV show? Undoubtedly, if successful, it would kill it off. How could you have a TV series and a film series running in parallel that directly contradict one another? The film idea dovetails with the growing suspicion that Who might bow out on the small screen shortly after the 50-year anniversary. Torchwood, in all likelihood is gone. The Sarah-Jane Adventures are sadly no more. Confidential is canned. In a very short space of time Doctor Who has been whittled away to the main show, and there are increasing ructions over production, money and quality in the mothership.
All told then, I don't really see an upside to the film. We've had six largely enjoyable seasons of NuWho that has given repeated, respectful nods backwards. It's all about to be usurped by a new film series that chucks it all in the bin.
The two films we have are cute curios, but they're hardly high quality. The abandoned film projects all looked awful. The TVM was dreadful. Yet the BBC appears to have learned nothing.
Doctor Who doesn't need a film. If it's coming to an end as a going concern on TV the natural development is to segue into a 'specials' format. Canon or the heritage aren't the issue I have with a new film. I simply fear it would be bloody awful - and history has plenty of warnings when it comes to big screen Who.
Actors respond to Torchwood Miracle Day criticism
Bill Pullman replies to criticisms of his performance.
Meanwhile another cast member gives her honest assessment.
Finally another cast member sums up the whole affair.


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We may not be Masters, but we will do our best. Here is the spot to ask those questions to further your playing skills!
This site is owned and operated by Team Compendium, Inc.
All content is © 2000-2011 Team Compendium, Inc.
The PokeGym is not affiliated with The Pokémon Company, International
or any anime or video game companies.


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Asses, asses, butts, etc...
Vintage Hairy Girls
Old school fetish bush retro
Brutal Passion
When The situation goes out of control
Cruel Video
Shocking.Rough.Tought.Not for nervous clients.
Retro Porn Archive
Having no computers and TVs around these people spent all their time fucking. We learned this epoch thoroughly and can tell you for sure that their sex was hotter! We have proofs to show you ? retro porn photos and films. Enjoy!
Vintage Cuties
If you like classic beauty of female body, if you like all natural shapes with hairy pussies and armpits, if you admire the fact that antique erotica and photography - not really just porn - it`s way more, its wtat`s make you scream!
Index 1
Index 2
Index 3
Index 4
Index 5
Index 6
Index 7
Index 8
Index 9
Index 10
Index 11
Index 12
Index 13
Index 14
Index 15
Index 16
Index 17
Index 18
Index 19
Index 20
Index 1
of 20
Adult Comics Book Net
Adult Flex
Vintage Stockings
Vintage Cuties
Vintage Pinup
Vintage Free
Retro Cunts
Antique Twat
Retro Drawing
Vintage nylons
Free Vintage
Vintage Lingerie
Boobs Vintage
Vintage Twat
Vintage XXX Art
Adult Comics Book
Hairy Hi
Hairy Kitten
Leg Fetish
Older With Young
XXX Porn Orgy
Vintage Movies
Sex in Sport


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April 25, 2013
By KENNETH MILLER
Assistant Managing Editor
The Metro Transportation Authority (MTA) pledged significant African American participation during the construction phase of the Metro Crenshaw/LAX Transit Corridor and also signed a project labor agreement to ensure that Blacks received adequate employment representation, but contractors have drastically under performed in the hiring of African Americans in the first phase of the Crenshaw Advanced Utilities Relocation PLA for Targeted Worker Attainment.
According to MTA internal documents obtained by the Sentinel, which revealed the number of individual hires, Blacks ranked lower than any other demographic group.
The Executive order on the Crenshaw Advanced Utilities relocation summary showed an appalling percentage of Blacks contracted. The report indicated that no Blacks were hired during the month of December 2012 when the bids went out and only 2.65 percent in the month of January 2013.
Los Angeles Mayor Antonio Villaraigosa and local Black community activist were outraged and the mayor demanded a more aggressive campaign to ensure Black participation and increase employment among African Americans as part of advanced utility relocation activities for the Crenshaw/LAX Transit Corridor Project.
After the mayor mandated the promoting of African American hiring during the construction phase, the number of Blacks hired in the month of February nearly doubled the percentage of the previous two months to 5.81 for February and escalated again in March to report its greatest gains yet reaching almost 8 percent.
"Finally, I think we are moving in the right direction because more African Americans are now included in the work force," said Mayor Villaraigosa. "However, I am not satisfied and will not be until I see that African Americans who live in this community are employed and reflected in the bottom line. I believe that it is only appropriate that residents of this community be active participants and work on this rail system being built. I want to see the number of people hired that represents the population of the community. They deserve it and I demand it. My legacy as mayor of the City of Los Angeles rides on it, and my commitment to Leimert Park and the entire Crenshaw community will not waiver."
The Metro Crenshaw/LAX Transit Corridor Project will extend from the existing Metro Exposition Line at Crenshaw and Exposition Bls. The Line will travel 8.5 miles to the Metro Green Line's Aviation/LAX Station and will serve the cities of Los Angeles, Inglewood, Hawthorne and El Segundo; and portions of unincorporated Los Angeles County. The project includes 6 stations and 2 optional stations: Crenshaw/Exposition, Crenshaw/Martin Luther King Jr., Leimert Park (optional), Crenshaw/Slauson, Florence/West, Hindry (optional), and Aviation/Century.
The new Metro Rail extension will offer an alternative transportation option to congested roadways and provide significant environmental benefits, economic development and employment opportunities throughout Los Angeles County. Riders will be able to make easy connections within the entire Metro Rail system, municipal bus lines and other regional transportation services.
The project purpose is to improve public transit service and mobility in the Crenshaw Corridor between Wilshire and El Segundo Bls. The overall goal of the proposed project is to improve mobility in the corridor by connecting with existing lines such as the Metro Green Line and the Expo Line.
The majority of the funding for the project came from Measure R, the half-cent sales tax initiative approved by Los Angeles County voters in November 2008.


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News & Notes: Game 53
Tuesday, May 31, 2011 (7:15 p.m.) – Knights Stadium
Radio: WWKB AM 1520, bisons.com
Buffalo Bisons (24-28, T4th(-8.0), North)
RHP Chris Schwinden (3-2, 2.36)
Charlotte Knights (22-27, 3rd(-5.5), South)
RHP Deunte Heath (4-2, 3.52)
TODAY'S GAME: Tonight, the Bisons take on the Charlotte Knights in the second game of a four-game series from Knights Stadium (7:15 p.m.). The Bisons have won four games in a row for the first time this season. The win streak includes last night's 7-5 victory in the series opener. Buffalo has also won six of its last eight games and is now an even 14-14 with one game left in May.
VS. THE KNIGHTS: The Bisons now have the 3-2 lead in their season series with the Knights. The two teams split a four-game series at Coca-Cola Field, May 21-24. In the five games against Charlotte, Buffalo hitters are averaging .301 with a .340 mark (18-53) with runners in scoring position.
SCHWING AND MISS: RHP CHRIS SCHWINDEN will make his ninth start of the season and his first since a May 21st outing against the Knights. The Triple-A rookie ranks tied for 3rd in the International League with his 2.36ERA. The righty has been particularly tough on the road this year where he is 2-1 with a 1.96ERA and 21 strikeouts in four starts and 23.0 innings of work.
HE'S THE MANNY: RHP MANNY ACOSTA has earned a save on three consecutive days. The righty closed out the second game of each doubleheader this weekend before collecting his fourth save of the season last night. The last Bisons pitcher to record a save on three straight days was RHP BUBBIE BUZACHERO from August 28-30, 2008. Acosta has now made eight consecutive scoreless appearances for Buffalo (8.2IP, 6H, 2BB, 14K).
GONE FISHIN': INF MICHAEL FISHER has homered in consecutive games, the third Bison to accomplish the feat this year (Nieuwenhuis, Martinez). Last night, Fisher also became the first Bisons' batter to score three times in a game this season. Fisher is hitting .300 (18-60) with three home runs and eight RBI in his first 17 career Triple-A games.
BISONS BITS: The Bisons collected a season-high 17 hits last night. The outburst raised the team's season average four points in one game (.244 – .248)…OF LUCAS DUDA is 5-10 with two home runs, three RBI, two walks and four runs scored in four games since being activated off the disabled list. The Bisons bullpen has allowed just one run in the last seven games (19.2IP, 15H, 29K).
METS UPDATE: The Mets (25-28) collected a 7-3 win over the Pirates Yesterday. Former Bisons' ace RHP DILLON GEE ran his record to 5-0 with eight strikeouts in seven innings of work. New York had 15 hits including three from former Bison INF RUBEN TEJADA. The Mets host the Pirates again tonight at 7:10 p.m.


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26-27 February 2014, Seoul - Korea
Co-organised by the OECD*, the Financial Services Commission and the Financial Supervisory Service of Korea, this event explored policies and good practices for supporting long-term savings and investments through financial education and financial consumer protection. In particular, the programme allowed in-depth discussion on:
The symposium was attended by an international audience of high-level officials and experts from ministries of finance and education, central banks, regulatory and supervisory authorities, other governmental organisations, international organisations, the private sector, academia, civil society and non-governmental organisations, particularly from Asia and OECD/INFE member countries.
Find more presentations from the meeting on SlideShare
Meeting documents
National strategies for financial education
Financial education in schools
International Gateway for Financial Education
* The contribution of the OECD is sponsored by the Japanese Government
Related Documents


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Zombie Christmas…. In February.
on February 21, 2010 at 5:05 am
Posted In: Uncategorized
Proof that even during the zombie apocalypse you better come up with a good gift for your girlfriend or your in trouble. Anyway I thought this was funny. Could have used some more editing and better sound design, but the[…]↓ Read the rest of this entry…


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Oil and Gas
AEI panel discusses National Petroleum Council report on availability of fossil fuels
In a recent report, the National Petroleum Council analyzed the political, economic and environmental factors that may be causing instability in the availability of fossil fuels. How big of a role will fossil fuels play in the future? Will production hit a peak or will supplies remain abundant? How will we generate energy in the future? During today's E&ETV Event Coverage, Lee Raymond, chairman of the National Petroleum Council; James Glassman, an American Enterprise Institute economist; and Kenneth Green, an AEI environmental expert, discuss the report and assess the future of fossil fuels.


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What is a good movie to watch? I am sure that most of you can rattle off at least a dozen movies off the top of your head. However, the real answer to that question is a bit more complex. It's often very subjective and greatly influenced by personal preferences. Your judgement might not necessarily align with that of a critic. Now, don't get me wrong. Reviews are important. They can often save you from a couple of hours of agony. But, just a review or two is often not enough to get a sense of how watchable a movie is. This is where aggregators come in. Services like Rotten Tomatoes, which collect and summarise critic as well as audience ratings, are a great resource for movie buffs.
Rotten Tomatoes features both Hollywood and Bollywood movies. However, it's obvious that the focus is on western movies, western media, and western audiences. If you are looking for your dope of Indian cinema, Rotten Tomatoes is not the place to be. The good news is that there are quite a few desi versions of the Tomatometer. Here are my top four picks.
Know Your Films
The design of this website is a bit old school, but it does get the job done. The home page shows a selection of entertainment news, upcoming movies, current movies, and some featured movies from the past. For current movies, the box office performance, as well as the latest reviews are displayed. Opening up a movie's page shows more info including cast, crew, sound track, and various reviews. There is, however, no average rating, or a quick way to see how a movie has been received. There are a few other useful features including the ability to create watchlists (requires registration), and watching popular Bollywood clips and trailers.
Filmy Pakode
This website trims all the fat and puts all the focus on the films and their ratings. The home page is just a collection of recently released movies along with their ratings, and a preview of the upcoming movies. The individual movie page contains average rating, along with information about movie cast, plot, and trailers and preview clips. Filmy Pakoda is simple and useful. But, the lack of even basic features like Search limits its utility.
Sahi Nahi
Sahi Nahi is the new kid in the block, and it's very obvious what the inspiration for this service is. The design is clean and pleasant with good use of typography. The home page gives you a quick overview of the latest movies along with their ratings, as well as the current top box office performers. You also have featured celebrities, movies, and blog articles. Every movie page features the critic rating along with excerpts of their review, trailer, and cast and crew information. It's worth noting here that Sahi Nahi follows a Rotten Tomatoes like rating system were each review is classified as either positive and negative. The overall rating is not an average of the scores assigned by each reviewer. The layout is responsive, hence, Sahi Nahi works well on a wide range of devices including phones and tablets.
[ Visit Sahi Nahi ]
The Review Monk
The Review Monk has an unmistakably Indian soul that will endear it to Indian movie fans. The beautiful slider on the home page showcasing some of the most memorable moments in Indian cinema will impress you straight away. The Review Monk, however, doesn't restrict itself to Indian cinema. Hollywood movies that have been released in India are also featured. The home pages offers a quick look at movies that are currently in the theatres, as well as top rated recent movies. The coming soon section displays the release dates of movies that will hit the theatres soon. There are even monthly reports and occasional blog posts about cinema for the film buffs looking for more. Every movie page has a TRM score, excerpts from reviews, cast and crew information, soundtrack list, trailer, and twitter buzz. There is even a spider chart breaking down the critic's ratings for you. The Review Monk score is an average, unlike Sahi nahi or Rotten Tomatoes. For mobile users, there's a free Android app that's once again simple but elegant and useful. You can register to build your profile by rating and reviewing movies you have watched, and adding movies you want to watch to your watchlist. In addition to Bollywood movies, The Review Monk is currently also tracking Tamil and Telegu movies. The idea behind The Review Monk might not be original, but the execution is really good.


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COVID-19 updates
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Meet the StaffFind a directory of doctors and departments at all Mayo Clinic campuses. Visit now.
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Our general interest e-newsletter keeps you up to date on a wide variety of health topics.
Vaginal discharge is a combination of fluid and cells continuously shed through your vagina.
Normal vaginal discharge helps keep vaginal tissues healthy, provide lubrication and protect against infection and irritation. The amount, color and consistency of normal vaginal discharge varies — from whitish and sticky to clear and watery — depending on the stage of your reproductive (menstrual) cycle.
Abnormal vaginal discharge — for instance, fluid with an unusual odor or appearance or discharge that occurs along with itching or pain — may be a sign that something's wrong.
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The Red Velvet Dress
19.99$ 39.99$
- Velours fluide et extensible
- Détails en diamant et tulle
Gladys, notre mannequin bouledogue française, porte la taille large.
Quelle taille choisir pour mon chien?
Shipping rates are fixed at $7 for all packages delivered to Canada. All delivery fees, including those paid for the return of an item, are non refundable.
Orders are shipped by Canada Post and are distributed throughout Canada. Once the order has been shipped, you can track it with the tracking number provided by Canada Post. The latter agrees to leave the parcel at the post office closest to the address provided in the purchase order, if any, where no one is present at the time of delivery. If this is the case, a Delivery Notice Card will be left at the door giving you the information you need to pick up your package. No signature is required at the time of delivery at the address provided in the purchase order, but a valid photo ID will be required at the post office to pick up your package.
The shipping time is 3-5 business days in the central regions of Quebec. Please add 2-3 business days for deliveries to rural areas in Quebec as well as anywhere else in Canada.
Whether online or in store, we have a no refund policy. Only exchanges or store credits are accepted.
Our policies are 30 days for online purchases and 14 days for store purchases. If you exceed the number of days since your purchase, we unfortunately can not offer you an exchange or store credit.
To qualify for an exchange or store credit, your item must be unused, in the same condition you received it, and still have its label. It must also be in the original packaging.
Several types of products can not be exchanged. Perishable goods such as food and treats can not be returned. Also, we do not accept products for personal use, sanitary or hygiene, dangerous products or flammable gases or liquids.
Other items that can not be returned:
* Gift cards
To make an exchange or receive a store credit, you must present a receipt or proof of purchase.
Please do not return your purchase to the manufacturer.
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We only replace an item if it is defective or damaged. If this is your case and you wish to exchange it for the same item, send us an e-mail at firstname.lastname@example.com and send us your article at: 2600, boulevard Laurier, local 155, Quebec, (Quebec), G1V 4T3, Canada.
To return a product, you must mail it to: 2600 Laurier Blvd., Suite 155, Quebec City, Quebec, G1V 4T3, Canada.
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If you are shipping an item with a value of $75 or more, please consider using a delivery service that allows you to track the shipment or secure delivery insurance. We can not guarantee we will receive the item you return to us.


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|International Space Station Imagery
high res (2.4 M) low res (95 K)
|ISS028-E-015593 (10 July 2011) --- This is one of a series of images showing various parts of the space shuttle Atlantis in Earth orbit as photographed by one of three crew members -- half the station crew -- who were equipped with still cameras for this purpose on the International Space Station as the shuttle "posed" for photos and visual surveys and performed a back-flip for the rendezvous pitch maneuver (RPM). A 1000 millimeter lens was used to capture this particular series of images.
Curator: JSC PAO Web Team | Responsible NASA Official: Amiko Kauderer | Updated: 10/30/2012


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Welcome to the Pre-Filmation Era!
He-Man slaying monsters with his trusty axe? It's here.
Tri-Klops kicking ass and taking names as a bounty hunter? Right here!
Teela as a hot blonde who fights like a fury? It's here.
The Goddess (or Green Goddess)? She's here as well.
Prince Adam as a womanizer? We have it!
Skeletor going commando? It's in da house!
Alfredo Alcala/Mike Texiera art? We got it!
This is the thread to talk and discuss about getting the figures or variants in MOTUC which are representative of Masters of the Universe before the more kid friendly and lighter Filmation revamp in mid-1983. Masters of the Universe originally showcased He-Man as a heroic barbarian from the jungle in a post-apocaylptic fantasy world. While this was the original version of He-Man, the majority of the fans was introduced to He-Man through the Filmation canon.
Hopefully, we will continue to get these repaints OR redos in MOTUC as bonus figures or some kind of extra.
Epic Heroes!
Dastardly Villains!
Fearsome Monsters!
Sister Threads:The Books of The Pre-Filmation Era
Pre-Filmation Mini-Comics
He-Man and the Power Sword
King of Castle Grayskull
Battle in the Clouds
The Vengeance of Skeletor
He-Man Meets Ram Man!
The Ordeal of Man-E-Faces!
The Terror of Tri-Klops!
The Menace of Trap Jaw!
The Tale of Teela!
The Magic Stealer!
The Power of... Point Dread!
Pre-Filmation Books/Records
Power of Point Dread! - Danger at Castle Grayskull
Pre-Filmation DC Comics
From Eternia with Death!
Fate is the Killer
Issue 1: "To Tempt the Gods"
Issue 2: "The Key to Castle Grayskull!"
Issue 3: "Within these Walls... Armageddon!"
Pre-Filmation Golden Books
The Sword of Skeletor
The Thief of Castle Grayskull
Caverns of Fear
The Trap
Pre-Filmation Coloring/Activity Books
A Big Coloring Book
An Activity Book
A Color and Activity Book
A Big Color/Activity Book
The Blonde Teela Thread
The Barbarian He-Man Thread
Mini-Comic Stratos Thread
The Goddess bio revealed
Pre-Filmation Era Web Sites:
Cloudy Climbs and Bridal Path Coloring book Stories


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Plastic Surgery – Professional Education
Penn State College of Medicine and Penn State Health Milton S. Hershey Medical Center are committed to establishing and maintaining high-quality Graduate Medical Education training programs.
Contact us
To learn more about educational programs in Plastic Surgery, call
Our institution provides the diverse patient population, dedicated faculty, excellent clinical and basic science departments, and nationally recognized research programs required to create an environment optimal for learning and for the development of future leaders in the art and science of medicine.
Learn more about the Plastic Surgery residency program listed below.
Residencies and Fellowships
Find more information about all of our residency and fellowship programs.
Plastic Surgery Residency
The Residency Training Program in Plastic Surgery is a six-year integrated program that has two residents per year. Dr. Donald Mackay is the chief of the Division of Plastic Surgery. Dr. Timothy Johnson is the residency program director, while Dr. Thomas Samson serves as the assistant program director. Qualified medical student applicants should apply for a residency position through the National Residency Matching Program. Questions about the residency program can be directed to Mrs. Tasha Cochran, Plastic Surgery Residency Coordinator.
Surgery Clerkships
The Department of Surgery offers both third-year clerkships as well as fourth-year electives and acting internships. Elective information can be found at the bottom of this page.


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June 15, 2017 – Employee Benefits Institute of America (EBIA), Webinar, Administrative Services Agreements for Health & Welfare Plans
As a leader in employee benefits law, Darcy Hitesman founded Hitesman & Wold in order to help public and private employers, insurers and third-party administrators nationwide stay informed and minimize the risk of non-compliance issues.
Hitesman & Wold provides a wealth of legal experience to their clients in the areas of ERISA, COBRA, HIPAA, Health Care Reform, welfare plans, cafeteria plans, HRAs, and VEBAs.
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In recognition and celebration of the 2016 Thanksgiving holiday, we are adjusting our hours…
Thursday, November 24th
We will be closed for Thanksgiving
Friday, November 25th
Our office will be closed, but emails will be monitored.
Have a safe and happy holiday!
Hitesman & Wold, P.A.


text:
Fiona Apple
Fiona Apple Maggart (born 13 September 1977), most famous as Fiona Apple, is a Grammy Award-winning American singer-songwriter and pianist.
- This world is bullshit. And you shouldn't model your life — wait a second — you shouldn't model your life about what you think that we think is cool and what we're wearing and what we're saying and everything. Go with yourself. Go with yourself.
- Acceptance speech, 1997 MTV Video Music Awards
- It was because of this guy I had gone out with and had been really, really close with. I really loved him. I felt that he was my best friend. But he was a teenaged guy, and they don't think a lot of times. He mistreated me and then he came back. I couldn't even be friends with him for awhile. I cared about him, but it was just a situation where he kept trying to be friends with me, but I knew that he just wanted to be friends with me so he could have the option of making a move on me whenever he wanted to. And because I was so infatuated with him, and even in love with him, I was always available for that. It made me feel weak every time I would fall for that. And I would look forward to him making a move on me, but I knew that it was wrong. I knew that he was playing with me. And after awhile, I didn't even care anymore because I wanted him so much.
- On Shadowboxer from Tidal,
- from Nuvo, "Fiona Apple: The NUVO Interview" April [1997]
Interviewer: I read a post on the Internet from a young girl who had been victimized by someone and her position was like, "I can talk about this now because Fiona Apple can talk about what happened to her." Do you look at yourself as a role model for women and girls who've had this experience?
Fiona: That's the only reason I ever brought the whole rape thing up. It's a terrible thing, but it happens to so many people. I mean, 80 percent of the people I've told have said right back to me, "That happened to me too." It's so common, and so ridiculous that it's a hard thing to talk about. It angers me so much because something like that happens to you and you carry it around for the rest of your life. No matter how much therapy you go through, no matter how much healing you go through, it's part of you. I just feel that it's such a tragedy that so many people have to bear the extra burden of having to keep it secret from everyone else. As if it's too icky a subject to burden other people with and everyone's going to think you're a victim forever. Then you've labeled yourself a victim, and you've been taken advantage of, and you're ruined, and you're soiled, and you're not pure, you know.
If I'm in a position where people are looking up to me in any way, then it's absolutely my responsibility to be open and honest about this, because if I'm not, what does that say to people? It doesn't change a person -- well, it does change a person but it doesn't take anything away from you. It can only strengthen you. It has made me so angry in the past. Like I wanted to say it to somebody. I really wanted somebody to connect with, somebody to understand me, somebody to comfort me. But I felt like I couldn't say anything about because it was taboo to talk about.
- Nuvo, "Fiona Apple: The NUVO Interview" April [1997]
- I definitely had an eating disorder. What was really frustrating for me was that everyone thought I was anorexic, and I wasn't. I was really depressed and self-loathing. For me, it wasn't about being thin, it was about getting rid of the bait attached to my body. A lot of it came from the self-loathing that came from being raped at the point of developing my voluptuousness. I just thought that if you had a body and if you had anything on you that would be grabbed, it would be grabbed. So I did purposely get rid of it...I mean, my plan is to gain enough weight that I can really be considered voluptuous, and do my 'First Taste' video. And I am preparing myself for what is going to happen. Because soon they will be saying that I'm fat. And it will hurt me.
- Rolling Stone, "The Caged Bird Sings" January [1998]
- My problem was that I felt ashamed of feeling sad or angry. Now, I don't hide my vulnerability in my lyrics. There's no way I was going to get raped and not get something out of it. I learned about power and hope and forgiveness. I like who I am now and I wouldn't be who I am if that hadn't happened.
- ELLE, "Fiona Apple is NOT the next Alanis, thank you" October [1996]
- I don't have a big thing about leaving my mark or being historic.
- Dr Drew interview (November 1999)
- Don't waste your crazy!
- Forever Fiona, interview by Liza Ghorbani (June 7, 2012)
Song lyricsEdit
Tidal (1996)Edit
- I got my feet on the ground and I don't go to sleep to dream;
You've got your head in the clouds and you're not at all what you seem.
This mind, this body and this voice cannot be stifled by your deviant ways.
So don't forget what I told you, don't come around, I got my own hell to raise.
- Sleep to Dream
Once my lover, now my friend;
What a cruel thing to pretend.
What a cunning way to condescend;
Once my lover, and now my friend.
Oh, you creep up like the clouds
And you set my soul at ease.
Then you let your love abound,
And you bring me to my knees.
- Shadowboxer
Oh, it's evil babe
The way you let your grace enrapture me,
When well you know I'd be insane
To ever let that dirty game recapture me.
You made me a shadowboxer, baby.
I wanna be ready for what you do.
I been swinging all around me
'Cause I don't know when you're gonna make your move.
- Shadowboxer
I've been a bad, bad girl.
I've been careless with a delicate man.
And it's a sad, sad world
When a girl will break a boy just because she can.
Don't you tell me to deny it.
I've done wrong and I want to suffer for my sins.
I've come to you 'cause I need guidance to be true,
And I just don't know where I can begin.
- What I need is a good defense
'Cause I'm feeling like a criminal
And I need to be redeemed
To the one I've sinned against
Because he's all I ever knew of love.
- Criminal
When the Pawn… (1999)Edit
- When the pawn hits the conflicts he thinks like a king
What he knows throws the blows when he goes to the fight
And he'll win the whole thing 'fore he enters the ring
There's no body to batter when your mind is your might
So when you go solo you hold your own hand
And remember that depth is the greatest of heights
And if you know where you stand then you know where to land
And if you fall it won't matter cuz you'll know that you're right.
- When the Pawn
- My derring-do allows me to
Dance the rigadoon around you.
But by the time I'm close to you,
I lose my desideratum and now you.
- To Your Love
- Hunger hurts, and I want him so bad, oh it kills.
'Cause I know I'm a mess he don't wanna clean up.
I got to fold 'cause these hands are too shaky to hold.
Hunger hurts, but starving works, when it costs too much to love.
- Paper Bag
- Do I wanna do right, of course
but do I really wanna feel I'm forced
to answer you, hell no.
I've acquired quite a taste for a well-made mistake,
I wanna make a mistake.
- A Mistake
I may be soft in your palm,
But I'll soon grow hungry for a fight, and I will not let you win.
My pretty mouth will frame the phrases that will disprove your faith in man.
So if you catch me trying to find my way into your heart from under your skin,
Fast as you can, baby
Scratch me out, free yourself.
- So keep on calling me names, keep on, keep on.
And I'll keep kicking the crap till it's gone.
If you keep on killing, you could get me to settle.
And as soon as I settle, I bet I'll be able to move on.
- The Way Things Are
And I will pretend
That I don't know of your sins
Until you are ready to confess.
But all the time, all the time,
I'll know, I'll know.
And you can use my skin
To bury secrets in,
And I will settle you down.
- I Know
Extraordinary Machine (2005)Edit
- I certainly haven't been shopping for any new shoes,
I certainly haven't been spreading myself around.
I still only travel by foot, and by foot it's a slow climb.
But I'm good at being uncomfortable, so
I can't stop changing all the time.
- Extraordinary Machine
- One man, he disappoint me;
He give me the gouge and he take my glee.
Now every other man I see
Remind me of the one man who disappoint me.
- Everything good, I deem too good to be true;
Everything else is just a bore.
Everything I have to look forward to
Has a pretty painful and very imposing before.
- I opened my eyes
While you were kissing me once more than once,
And you looked as sincere as a dog.
Just as sincere as a dog does,
When it's the food on your lips with which it's in love.
The early cars
Already are
Drawing deep breaths past my door.
And last night's phrases,
Sick with lack of basis,
Are still writhing on my floor.
And it doesn't seem fair
That your wicked words should work
In holding me down.
No, it doesn't seem right
To take information
Given at close range
For the gag
And the bind
And the ammunition round.
- Conversation once colored by esteem
Became dialogue as a diagram of a play for blood.
Took a vacation, my palate got clean.
Now I could taste your agenda
While you're spitting your cud.
- Not About Love
- If you don't have a date
Go out and sit on the lawn
And do nothing
'Cause it's just what you must do
Nobody does it anymore.
- Waltz (Better Than Fine)
About Fiona AppleEdit
- Well, you ain't Fiona Apple. And if you ain't Fiona Apple, I don't give a rat's ass.
- Officer Barbrady, after Barbra Streisand asks him if he knew who she is
- South Park, "Mecha-Streisand" [1.12]
- And then I went over to the concession stand to get some tea and I ran into Fiona Apple, and I was like, "Who do you think you are, Fiona Snapple?"


text:
How to make a loop on your crochet toy:
Pull it trough the top of the head and then back, leaving a small loop.
Then make a chain as long as twice the toy.
The loop has to be as long as the toy itself can pass through it, which allows you to tie it to your bag easily.
(the ugly bunny bag charm on the picture is not my own pattern. Find it here)
Then leave a long tail so you can pull that tail back trough the same hole you pulled it from the beginning (from the top of the head trough the bottom of the body).
And tie the two tails together.
Then hide it in the toy.
Now you have a brand new bag charm! Easy, isn't it?! :)
P.S You can make the loop smaller and with the color of the hair then add a key holder


text:
Her Majesty The Queen and Her Royal Highness The Princess Royal are to perform a series of joint engagements in Cumbria on Wednesday, being one of the only times both Her Majesty and the Princess Royal have performed engagements together.
First, Princess Anne and The Queen will visit Kendal Town Centre in Cumbria, before visiting James Cropper Speciality Papers Limited later and then The Queen and her only daughter will visit Lake Windermere.
Princess Anne was the most active member of the Royal Family last year. Although the press rarely give her the recognition she deserves, last year she performed the most engagements in the UK (485) followed by Prince Charles (480) and then The Queen (425).
It is believed that the engagement may have been planned originally to be done by The Queen and the Duke of Edinburgh, though due to the Duke's recovery, Princess Anne stepped in to accompany Her Majesty to this particular set of engagements.
The Earl of Wessex attended a garden party at the Palace of Holyroodhouse at the beginning of the month with Her Majesty, whilst the Duke of Edinburgh remains at Windsor Castle recovering from exploratory surgery which took place last month. He is expected to return to public engagements sometime after the Royal Family's annual summer break at Balmoral Castle in Scotland.
photo credit: Defence Images & Royal Navy Media Archive via photopin cc


text:
Take a look at this suggested timeline when you are interested in applying to U.S. colleges
12 to 18 months before departure
Evaluate your reasons for wanting to study in the USA taking into consideration :
- motivation, objectives, why the USA and not elsewhere ?
- your future plans : academic or employment opportunities
- your English proficiency and academic ability
- time required to earn an American degree
- estimated cost of study & scholarship opportunities
June – September
Select 5 or 6 universities on the basis of their programs, degrees offered, accreditation, level of selectivity, cost, location and size
July – August
Find out which standardized tests are required (TOEFL, TSE, IELTS, ACT, SAT, GRE, GMAT) and register to take them in October or November. Forms are available at the Commission.
August – September
Write to 5 or 6 universities to request application forms for admission and financial aid.
October – February
- request transcripts from your department or university and prepare literal translations
- have the translations of degrees and transcripts certified at the Commission
- apply for financial aid in Belgium and the USA
- have professors send recommendation letters
- send applications to universities well in advance of deadlines
February – April
Wait for acceptance and rejection letters from the universities.
March – April
Contact universities to which you have applied, but from which you have not yet received a response.
April – June
Accept offer of admission from your preferred university. Decline offers from other universities where you were also accepted. Contact the university housing office to reserve university owned housing. Contact the university Foreign Student Advisor for any specific information concerning arrival and orientation. Contact the Commission for pre-departure information.
Upon Arrival
Contact the Foreign Student Advisor.


text:
Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01212380
Recruitment Status : Completed
First Posted : September 30, 2010
Last Update Posted : May 9, 2016
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
This phase I trial is studying the side effects and the best dose of carfilzomib in treating patients with relapsed or refractory chronic lymphocytic leukemia(CLL),small lymphocytic lymphoma(SLL), or prolymphocytic leukemia (PLL).
|Condition or disease
|B-cell Chronic Lymphocytic Leukemia Hematopoietic/Lymphoid Cancer Prolymphocytic Leukemia Recurrent Small Lymphocytic Lymphoma Refractory Chronic Lymphocytic Leukemia
|Drug: carfilzomib Other: Cytokine Assessment Other: Pharmacodynamic Studies Other: Proteosome Inhibition Assessment Other: Pharmacogenomic Studies
|Phase 1
I. To determine the dose limiting toxicity (DLT) and maximal tolerated dose (MTD) of carfilzomib in patients with relapsed or refractory Chronic Lymphocytic Leukemia(CLL) / Small Lymphocytic Lymphoma (SLL) and Prolymphocytic Leukemia (PLL).
II. To evaluate the safety and toxicity profile of carfilzomib in relapsed or refractory chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL)/prolymphocytic leukemia (PLL).
I. To evaluate efficacy of carfilzomib therapy in relapsed or refractory chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL)/prolymphocytic leukemia (PLL) to justify future phase II studies.
II. To determine the degree and duration of cellular proteosome inhibition induced by carfilzomib and relationship of this to pharmacodynamics, response and toxicity.
III. To determine the pharmacokinetics (plasma and cellular) of carfilzomib and relationship of this to proteosome inhibition, pharmacodynamics, response, and toxicity.IV. To examine the effect of carfilzomib on pharmacodynamic parameters including cytokines, changes in downstream targets including NF-kappa B (p50/p65 binding; I-kappa B level, P-I-kappa B level,select target genes), p53 (p53 nuclear levels, p53 nuclear binding, and select target genes), ER stress proteins, and p73.
OUTLINE: This is a dose-escalation study of carfilzomib.Patients receiving carfilzomib intra-venous(IV) over 30 minutes once daily, on days 1, 2, 8, 9, 15, and 16. Treatment repeats every 28 days for up to 12 courses in the absence of disease progression or unacceptable toxicity.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|21 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase I Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)/Prolymphocytic Leukemia (PLL)
|Study Start Date :
|October 2010
|Actual Primary Completion Date :
|July 2014
|Actual Study Completion Date :
|September 2015
Experimental: Arm 1
Patients receive carfilzomib IV over 30 minutes once daily on days 1, 2, 8, 9, 15, and 16. Treatment repeats every 28 days for up to 12 courses in the absence of disease progression or unacceptable toxicity.Performance of pharmacology, pharmacodynamic and pharmacogenomic studies allow assessment of carfilzomib mechanism of action and also to understand how the variability of these different features correlate with clinical benefit/response and also toxicity.
Drug: carfilzomib
Given IV infusion lasting 30 minutes. Will be administered IV at a specified dose in mg/m2 QDx2 weekly for 3 weeks (days 1, 2, 8, 9, 15, and 16). The first and second dose will always be administered at 20 mg/m2.
Other Name: PR-171
Other: Cytokine Assessment
TNF-α,IFN-γ,IL-6,IL-8,IL-10,and IL-1β pre-dose, completion, 30 minutes, 2 hours, 6 hours, and approximately 24 hours from initiation of therapy on days 1 and 8 of treatment. These will be assessed utilizing standard ELISA or flow cytometry methodology. Other cytokines or soluble factors may be assessed that relate to drug toxicity or response. After 6 patients are examined in each group, the time points or number of cytokines examined may be changed to decrease time points examined. Cytokines will be examined by a multiplex flow cytometry assay or ELISA. Other cytokines, chemokines, or soluble factors may be assessed on residual material not used for these studies.
Other Name: correlative studies
Other: Pharmacodynamic Studies
Based upon our preliminary data changes occuring in vivo during carfilzomib treatment will be determined and if their occurrence correlates with both clinical response and development of cytokine release. These studies will be performed from CD19 selected CLL cells at screening, pre-treatment, 4 hours, and 24 hours post-therapy on days 1 and 8 of treatment; end of therapy evaluation, and at time of relapse (in responding patients). These studies will include assessment of NF-κB (p50/p65 binding; I-κB level, P-I-κB level, select target genes), p53 (p53 nuclear levels, p53 nuclear binding, and select target genes), p73, and ER stress response. Standard Western Blot, EMSA, RT-PCR will be done to complete these studies.
Other Name: correlative studies
Other: Proteosome Inhibition Assessment
Proteosome inhibition on CLL cells will be examined at screening, pre-treatment and post-treatment (immediately after completion of drug) days 1, pre-treatment day 2, day 3 (optional), day 5 (optional),pre and post-treatment days 8, pre and post-treatment days 9, day 10 (optional),day 12 (optional), and day 15 (optional).
Other Name: pharmacological studies
Other: Pharmacogenomic Studies
Germ line DNA from a buccal swab and bone marrow fibroblasts will be obtained at baseline screening for possible examination of SNP polymorphisms that may correlate with response and toxicity to carfilzomib therapy. Tumor DNA will be derived from samples obtained at baseline for the p53 mutational studies. SNPs related to drug metabolism, response, or toxicity to therapy, cytokine release, and tumor biology may be examined. Other SNPs may be used in the future. Given the potential for contamination in the recipient, recipient DNA from a buccal swab and/or saliva will be obtained at baseline screening for examination of SNP polymorphisms that may correlate with response, toxicity, and pharmacokinetics.
Other Name: correlative studies
- Determine safety of carfilzomib by evaluating the toxicity profile. [ Time Frame: Up to 24 months ]
The safe use of carfilzomib will be assessed by:
- Determining the dose limiting toxicity and maximal tolerated dose of carfilzomib in patients with relapsed or refractory chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL) and prolymphocytic leukemia (PLL)
- To evaluating the toxicity profile of carfilzomib in relapsed or refractory chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL) and prolymphocytic leukemia (PLL)
- To evaluate the efficacy of Carfilzomib therapy in relapsed or refractory chromic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL)/prolymphocytic leukemia (PLL) [ Time Frame: Up to 24 months ]
Efficacy of this therapy is evaluated by:
- Determining the degree and duration of cellular proteosome inhibition and relationship to pharmacodynamic (PD), response and toxicity.
- Determining the pharmacokinetics(plasma and cellular)of carfilzomib and relationship to proteosome inhibition, PD, response and toxicity.
- Examining the effect of carfilzomib on PD parameters, changes in downstream targets including NFkB (p50/p65 binding;IkB level, P-IkB level, select target genes), p53 (p53 nuclear levels, p53 nuclear binding, and select target genes), ER stress proteins, and p73
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Previously treated patients with a diagnosis of chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or prolymphocytic leukemia (PLL) by NCI Criteria with intermediate or high risk B-Cell chronic lymphocytic leukemia (CLL)(Modified Rai stage) satisfying at least one of the criteria for active disease requiring treatment;patients with a history of Richter's transformation are eligible if they now have evidence of chronic lymphocytic leukemia (CLL) only, with < 10% large cells in the bone marrow
- Massive or progressive splenomegaly and/or lymphadenopathy; or need for cytoreduction for stem cell transplant
- Anemia (hemoglobin < 11 g/dl) or thrombocytopenia (platelets < 100 x 10^9/L)
- Presence of weight loss > 10% over the preceding 6 month period
- NCI grade 2 or 3 fatigue
- Fevers > 100.5 °C or night sweats for greater than 2 weeks without evidence of infection
- Progressive lymphocytosis with an increase of > 50% over a 2 month period or an anticipated doubling time of less than 6 months
- Creatinine Clearance (CrCl) > 15mL/min
- Alanine aminotransferase (ALT) < 3X upper limit of normal (ULN)
- Bilirubin =< 2 times the upper limit of normal, unless disease related
- Platelets >= 20 x 10^9/L and absence of active bleeding
- Patients must have an ECOG (Eastern Cooperative Oncology Group) performance status =< 2
- Patients must not have secondary cancers that result in a life expectancy of <2 years or that would confound assessment of toxicity in this study
- Patients of all racial/ethnic groups are eligible for the study if they meet eligibility criteria outlined-
- Patients must provide written informed consent
Exclusion Criteria:
- Absence of previously treated chronic lymphocytic leukemia (CLL)
- Female subject that is pregnant or breastfeeding; women of childbearing potential and men must agree to use adequate contraception prior to study entry, duration of study participation,and 30 days following study completion; should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately;confirmation that the subject is not pregnant must be established by a negative serum -human chorionic gonadotropin (beta-hCG) pregnancy test result obtained during screening; pregnancy testing is not required for post-menopausal or surgically sterilized women
- Patients with congestive heart failure (CHF)in whom pre-treatment hydration would be prohibitive;New York Heart Association (NYHA) Class III/IV CHF is excluded
- Patients who have had treatment for chronic lymphocytic leukemia (CLL) within 2 weeks, although palliative steroids are acceptable
- Patient unable to give written informed consent
- Failure to recover from toxicity of previous radiotherapy or chemotherapy to grade 1
- Patients with active infections requiring intravenous (IV) antibiotic/antiviral therapy are not eligible for entry onto the study until resolution of the infection; patients on prophylactic antibiotics or antivirals are acceptable
- Patients who have previously taken bortezomib
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01212380
|United States, Ohio
|Ohio State University Medical Center
|Columbus, Ohio, United States, 43210
|Principal Investigator:
|Jennifer Woyach, MD
|Ohio State University Comprehensive Cancer Center
|Responsible Party:
|Jennifer Woyach, Principal Investigator, Ohio State University Comprehensive Cancer Center
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
NCI-2010-01884 ( Registry Identifier: CTRP (Clinical Trial Registration Program) )
|First Posted:
|September 30, 2010 Key Record Dates
|Last Update Posted:
|May 9, 2016
|Last Verified:
|May 2016
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Prolymphocytic Leukemia
Leukemia, Lymphoid
Leukemia, Lymphocytic, Chronic, B-Cell
Leukemia, Prolymphocytic
Neoplasms by Histologic Type
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Leukemia, B-Cell


text:
The RJ-4030 enables field based workers to print 4" sized high quality documents and labels in tough conditions. Fast, light and tough, this portable printer is easy to use and ideal for printing customer invoices, on-the-spot notices or fines, shipping labels and statements of work.
As well as featuring a compact robust design, the printer is packed with features. Offering a fast print speed of 5ips/127mm per second, the machine also offers a wide range of connectivity options including USB, serial and wireless.
With direct thermal technology there is no ink or toner required, the printer is perfect for workers on the go. The machine comes with IP54 certification .
Brother is a multinational company of Japanese origin with offices throughout the world. Brother has a rich range of communication solutions: from the wide range of desktop printers, able to satisfy every type of users to mobile printing devices; from scanning solutions to electronic labeling machines; software solutions for optimization and monitoring of installed printers to innovative applications of optics and video conferencing systems. The company has more than 100 years of history and experience.


text:
- Editor Rating
- Rated 1 stars
- Really Bad
- Venture Alliance
- Reviewed by:
- Published on:
- Last modified:
- LegitimacyEditor: 0%
Venture Alliance (venture-alliance.com) was launched in September 2015 providing Bitcoin investment services from the United Kingdom. The company's legitimacy has been evaluated based on the items listed below. Every individual item has been checked for the presence of obvious red flags or warning signals. If these are present, an explanation detailing what triggered them has been included. A detailed description of the reasons to evaluate each of the included items can be found below the table.
Note that items with a warning instead of a flag indicate that these could occur at a legitimate company. For example, legitimate companies will normally try to persuade you into buying their products. Multiple warnings will, however, still trigger a flag. A description for the listed items is provided below. This list is meant to assist with identifying obvious scams, and therefore does not provide any guarantees that a company is truly legitimate.
Phantom Riches
The most common tactic used by fraudsters is called "phantom riches". By dangling the prospect of wealth such as "big payoffs", the scam artist tries to get you to stop thinking logically.
Using the fear of missing out, fraudsters create a false sense of urgency with statements such as "last chance" or "only so few available". This causes people to agree hastily, before even having the opportunity to think about what they're doing.
Source Credibility
Persuasion is more likely when the source presents itself as being credible, expert and trustworthy. Common tactics used by scammers to make themselves look legitimate include using fake websites or hacked emails and pretending to be someone they are not. Alternatively, sources can also be external with claims such as "Warren Buffet has already invested in this".
Social Proof
Fraudsters take advantage of herd behavior by creating the illusion of consensus or social proof that the investment is legitimate with claims that "everybody is already doing it", or referral programs in which members encourage their friends and associates to invest as well. This automatically triggers something in the head that says: "if everybody [or someone from the inner circle] wants it, it must be good".
A business is likely to receive far more of our trust when it provides a lot of free value, because of the rule of reciprocity which causes us to tend to feel obligated to return favors after people do favors for us
Guaranteed Return
All investments carry some degree of risk, so a guaranteed profit is a clear red flag.
High Return / Low Risk
Like a guaranteed return, a high return / low risk investment opportunity also defies the common risk-return relationship. The best advice is an old one: "if it sounds too good to be true, it probably is".
Overly Consistent, Positive Returns
Cryptocurrency markets are among the most volatile markets, hence the performance of any related product or service is also expected to fluctuate.
Downplaying Risks
The fraudster will do anything to provide a false sense of security, such as presenting some form of external risk insurance for the investment. In reality, insurance is only seldom acquired and guarantees typically lack substance. Dummy companies are often used to act as the guarantor or insurer. Other actions may include misrepresenting, or even non-disclosure of risks involved.
Secretive or Complex Trading Strategy
Even in the world of cryptocurrencies one should be skeptical about special competitive advantages without any proper disclosure, or when the information is incomprehensible or incomplete. Too often only the positive elements are accentuated.
Website Available
Considering the importance of domains and websites in the internet age, there is almost no reason for a legit company not to have one.
Website Registration Details
Very few scam websites survive longer than one year, so domains are generally registered for just one year unless otherwise required for the specific domain. For the same reason, websites created less than one year ago should be considered suspicious.
Website Design
Amateurish, cluttered and disorganized websites can point to a scam as many scam sites use text and images from legit websites and other sources which may not work together very well.
Grammar on Website
Many scammers have limited English proficiency.
Payments Options
Even though cryptocurrency payment options are logical for a cryptocurrency company, it is also very convenient for scammers as the recipient essentially remains anonymous. The same goes for services such as Western Union and Moneygram. Hence a lack of alternative payment options should still be considered a warning signal.
Service Disruptions & Unbusinesslike Conduct
Especially Ponzi scheme promotors will encourage participants to "roll over" their investment. These schemes are not very fond of investors cashing out, which may lead to difficulties receiving payments and a non-responsive or difficult to reach customer service.
Contact Information
Legitimate companies have very little reason not to list their contact information.
Business Verification
First, you should never hand your hard-earned money over without knowing where it is going. Second, you should do a background check to avoid handing it to a known scammer. Be weary of people without an online identity. Scammers will typically try to hide their identity or conceal their true identity to avoid being easily discovered. Especially investment services are normally subject to strict regulatory oversight, so a registration should not be hard to find.
Independent Audits
Audits certainly do not root out every instance of fraud, but auditors do have a responsibility to detect errors or fraud in the company's financial statements.


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I am considering extending/connecting the downspouts of my house to some pvc piping which I will run underground. What are things that I need to keep in mind?
Specifically, I have the pvc piping but the joints I have are for 90 degree angles. Is it essential that they be at 45 degree instead?
Also, is it essential that the pvc piping be sloped down an inch or two for every length of pipe (in other words whats the difference if they are just level, wont the water run off anyways)?
Can I dig the trench and put the drainage piping next to the house or is it essential that the drain pipes be a couple feet away from the house as suggested by This Old House.
I live in the northeast where winters stay below freezing for several weeks (sometimes a couple months) of the year.


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Habu is one of the pen names of a former supersonic spy jet pilot, intelligence agent, male model, movie actor, and diplomat. A wild youth in South East Asia was spent enjoying whatever sexual opportunities came his way, and much of his gay male writing is about recalling incidents from those days and inventing ones he'd perhaps have liked to experience. He now leads a very quiet and ordinary life.
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