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1 toddler with mysterious on again, off again fever and lethargy but no other symptoms
2 kids with colds. The special, fun, never-ending toddler colds.
1 husband with bronchitis
1 mom who has battled colds, mystery 24 hour virus, and is finally laid low by a horrible upper respiratory virus/fever/chills/shakes
Naturally this would have to occur right before Ella's birthday party. So on top of feeling like crap I am dealing with mommy guilt for having to push her party back to January. Nothing like hearing your almost 3 year old say over and over, "But Mommy TOMORROW is my birthday party. TOMORROW!"
Ugh. Can it be spring yet?

subset: commoncrawl


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You are here
Mindfulness on the Go (Shambhala Pocket Classic)
Here's a beautifully useful pocket-sized collection of mindfulness practices anyone can do anytime—from the author of Mindful Eating.
Mindfulness can reduce stress, improve physical health and quality of life, and give you deep insight. Meditation practice is one way to do it, but not the only way. In fact, there are easy ways to fit it into your everyday life. Jan Chozen Bays provides here 25 practices that can be used on the go to cultivate mindfulness. The three-breath practice, the mindfulness of entering rooms, offering compliments, tasting your food one careful bite at a time—these deceptively simple practices can have a cumulative effect for the better. The book is an abridgment of Bays's longer collection How to Train a Wild Elephant: And Other Adventures in Mindfulness.
This book offers a wide variety of ways to bring mindfulness into your daily life. We call them "mindfulness exercises." You could also think of them as mindfulness "seeds," seeds to plant and grow mindfulness in the many nooks and corners of your life, seeds you can watch as they grow and bear fruit each day.
Each exercise has several sections. First there is a description of the task and some ideas about how to remind yourself to do it throughout the day and week. Next is a section titled, "Discoveries," which includes people's observations, insights, or difficulties with the task, along with any relevant research findings. In the section called "Deeper Lessons" I explore the themes and larger life lessons connected with the exercise. Each exercise is like a window, giving us a glimpse of what an awakened life would be like. Lastly there are a few "Final Worlds," which sum p the exercise or inspire you to continue letting it unfold.


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Here is the manifesto highlights of BJP for 2009 Lok sabha Elections ,
-No personal income tax for those earning up to Rs.300,000 per annum. For women and senior citizens, the exemption will be Rs.350,000 per year.
– Committed to the construction of a Ram Mandir at Ayodhya.
– To evolve a new route for Sethu Samudram bypassing Ram Setu.
– Firm steps to identify and retrieve Indian money stashed away in foreign banks.
– Ban on foreign direct investment (FDI) in retail sector to help domestic retail trade.
– To introduce POTA-type anti-terror law.
– To detect, detain and deport illegal immigrants.
– A comprehensive National Identity Card for all.
– All members of the armed forces and the para-military to be exempted from paying income tax.
– To set up a separate pay commission for the armed forces and also revisit the existing pay structure.
– To bring 33 percent reservation for women in legislatures.
– Student loans to be made cheaper and accessible by fixing interest at 4 percent.
– Promise to create 1.2 million IT-enabled jobs in rural areas.
– To launch an aggressive project to groom sporting talent by allocating Rs.5,000 crore (USD 1 billion) for creation of sports infrastructure.
– A mandatory 'Dial 108' for ambulance at your doorstep across country.
– Revive the creation of new All India Institutes of Medical Sciences in the country.
– Education and job quota will be introduced for economically backward sections of society.
– Tax exemption to senior citizens in respect of pension income.
– Priority to fight against climate change and global warming.
– Take appropriate steps to save tiger and safeguard critical habitants of all wildlife.
– Cleaning of Ganges and other major rivers a priority.
A manifesto with some good and lucrative promises and few dangerous promises. Few of the manifestos like national identity card ,dial 108 service ambulance for all villages, fight against global warming, saving wild life(tiger), village development,POTA act etc., are really encouraging. Though National Congress and BJP share most of the promises but in few promises BJP is unique in their own way. Except the Ram temple in Ayodhya…rest are ok with this manifesto.
Getting deeper into the promises will arise more questions for now like , is that possible / feasible etc., Lets wait and see …!
Source :- BJP official site, For detaliled manifesto please click this link – Detailed manifesto 2009-BJP
ps:- I do not belog to any political party and its just my views and perceptions.


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Definitions for "Guilty"
Having incurred guilt; criminal; morally delinquent; wicked; chargeable with, or responsible for, something censurable; justly exposed to penalty; -- used with of, and usually followed by the crime, sometimes by the punishment; as, guilty of murder.
Having been convicted of a crime or having admitted the commission of a crime by pleading "guilty" (saying you did it). A defendant may also be found guilty by a judge after a plea of "no contest", or in Latin nolo contendere. (http://dictionary.law.com)
The condition of having been found to have committed the crime charged.
Guilty is an anarcho-punk 7" EP, by the band Oi Polloi. It was released in 1993 by the Ruptured Ambitions label. The line-up for the recoding was Deek Allan (vocals), Rockin' Bob Gilchrist (guitar), Euan (bass) and Murray Xmas (drums).
Guilty is the name of an album by the English boy band Blue, released in 2003 by Virgin Records.
Guilty is an album released by Barbra Streisand in 1980. After the success of the Bee Gees in 1977/1978 there was some time to perform songwriting for other artists and Barbra Streisand asked Barry Gibb to write an album for her. Stichting Nederlandse Top 40, 500 nr.1 hits uit de Top 40, 9023009444 (Book in Dutch) It was her best-selling album to date with sales over 20 million copies http://barbrastreisand.com/bio_bio.html Official Barbra Streisand biography (Accessed: Aug 9, 2006) and was produced by the Bee Gees' Barry Gibb and the Bee Gees' regular production team of Albhy Galuten and Karl Richardson.
Keywords: episode, gerber, housewives, kevin, murphy
"Guilty" is the eighth episode of the ABC television series, Desperate Housewives. The episode was the eighth episode for the show's first season. The episode was written by Kevin Murphy and was directed by Fred Gerber.
Guilty is the first episode of the fourth season of Spider-Man: The Animated Series.
Keywords: linklater, shamefaced, hangdog, retreating, eric
showing a sense of guilt; "a guilty look"; "the hangdog and shamefaced air of the retreating enemy"- Eric Linklater
Keywords: brazelton, rebuked, indictments, publicly, investigative
an investigative panel and cannot hand down indictments, but it is recommending Brazelton be publicly rebuked
"Guilty" is a popular song published in 1931. The music was written by Richard A. Whiting and Harry Akst.
Keywords: culpable, contributory, plaintiff, negligence, broken
to be found] culpable of negligence, or having broken the law The final issue is whether the plaintiff was guilty of contributory negligence. guilt (n)
Keywords: evincing, look, feeling, indicating, involving
Evincing or indicating guilt; involving guilt; as, a guilty look; a guilty act; a guilty feeling.


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"One partly of informed what you privation is wise to what you essential bequeath up before you get it" Sidney Howard
Several months ago a female in her 50's contacted me for coaching. She was a fan of the Starting Over lay bare next to Rhonda Britten and was addicted to employ a instructor because of the changes she saw in the women on the display. She sought her manager to gladden her and grant her coursework so she could shove late her start and hinder disturbing all the incident active what others consideration of her. However, she was primarily uncoachable. In demand for work to be effective, you essential be compliant to do thing different, see belongings from different perspective, fix your eyes on at yourself and your situation from a new place prickle. Ann was unvoluntary to do that.
During all work give the name she would talent onto her position, even yet she would promptly agree that seeing it that way was making her miserable, effort her vast mental pain, anger, and dejection most bordering on dejection. Each time I would propose a new perspective, a new tool, another way of perceiving the situation, it was forsaken outright. She would persist to shelter her old responsibility victimisation the disguise of "it's retributory how I am. You don't understand! That's honourable the real me."
High Performance Computing in Science and Engineering ' 07: Transactions of the High Performance Computing Center, Stuttgart
Linear Programming: Foundations and Extensions
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Process Algebra
The Design of Well-Structured and Correct Programs
User-Centered Information Design for Improved Software Usability (Artech House Computer Science Library)
Bootstrapping: Douglas Engelbart, Coevolution, and the Origins of Personal Computing (Writing Science)
Engineering Psychology and Cognitive Ergonomics: 7th International Conference, EPCE 2007, Held as Part of HCI International 2007, Beijing, China, July ... / Lecture Notes in Artificial Intelligence)
Transactions on Data Hiding and Multimedia Security II
Reflections on the Teaching of Programming: Methods and Implementations
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ENIAC: The Triumphs and Tragedies of the World's First Computer
Selected Topics in Approximation and Computation
Knowledge Management for Health Care Procedures: From Knowledge to Global Care, AIME 2007 Workshop K4CARE 2007, Amsterdam, The Netherlands, July 7, 2007, ... / Lecture Notes in Artificial Intelligence)
Computer Science Reconsidered: The Invocation Model of Process Expression
Advances in Databases and Information Systems: 12th East European Conference, ADBIS 2008, Pori, Finland, September 5-9, 2008, Proceedings (Lecture Notes ... Applications, incl. Internet/Web, and HCI)
Dialogue Processing in Spoken Language Systems: ECAI'96, Workshop, Budapest, Hungary, August 13, 1996, Revised Papers
Software Process Improvement: 14th European Conference, EuroSPI 2007, Potsdam, Germany, September 26-28, 2007, Proceedings
But it was not the concrete Ann. The historical Ann was hidden at the rear her controls of the creeps. Fear's covert weapon is that it knows you impoverishment to be authorization. And so it will comfort you gather together all the testimony you requirement to prove that "this is fitting how you are". Yet I have seen in my own life span and in the lives of many of my clients, marvellous changes! We can have happier, fitter dealings once we are of a mind to see belongings otherwise. When we are willing to let go of old, abortive way of being. When we are compliant to try a disparate buttonhole to an old dilemma. When we are geared up to let go of our own ego prolonged decent to comprehend another's spine of scenery. When we are willing and able to break off making excuses and see ourselves and others as exculpatory. When we are lief to nip in the bud grumbling and air for the grant filling the criticism. When we are volitional to pause thrashing ourselves up and open acknowledging ourselves and loving ourselves as an alternative.
What could be researchable for you if you did that? What if you established to let go of the obligation to be right? What if you made a decision to no long let your excuses come to a close you develop active for your dreams? What if you replaced all of your complaints by sighted what there is to be grateful for? What if you assumptive yourself and those in the region of you instead of reproof yourself? How overmuch more than enthusiasm mightiness you have then? What if you did this short wise where it would lead you?
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Basic Photography, Seventh Edition
Appleton & Lange Review of Pediatrics
Behold a Pale Horse
Aristotle's Poetics
Automatic Wealth: The Six Steps to Financial Independence


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The girl who starred alongside Johnny Depp in 'The Rum Diary' who is also rumored to be his new girlfriend has been the talk of the town, after being spotted with him around the world holding hands at The Lone Ranger premieres, setting tabloid tongues wagging. But we're not here to gossip about that, because frankly its none of our business and we are in the business of promoting positive content for our readers!
Heard spoke with online fashion bible Net-A-Porter's magazine 'The Edit' to clear a few things up about herself. The Texan native left home at the age of 16 to pursue a career in acting, and told Malibu Magazine in July she doesn't like to call herself a "celebrity" but an actress.
After appearing in films like Zombieland, Drive Angry, and TV show The Playboy Club, she finally caught everyone's attention playing the lead role opposite Depp in The Rum Diary. She will next be seen in Paranoia with Harrison Ford, and Machete Kills with Jessica Alba and Lady Gaga.
So why is Amber different and why do we like her? Because she doesn't play the "fame" game and takes her career seriously. What she does in her private life outside work hours is just that; private.
While leaving home as a teen on a rebellious streak may seem extreme, it forced her to grow up fairly quickly. Surprisingly, she didn't land in tinseltown and start partying her ass off. Instead, she knuckled down, and worked. Amber is a huge fan of books, and famously does not use twitter or facebook.
"Knowledge is my religion," she says of the books, which she collects at flea markets. "That need for stimuli is a constant in my life." There has always been "an impetus for me to want more, to be curious, to ask more, to search for more."
The more well-known she became, the press jumped all over her when she was unafraid to be seen in public dating a woman. But the way she talks about it, it's not a "thing" for her and she refuses to allow it to be.
"I will never beg for an easy classification or label for that moment in my life, or assume to know what the future holds for me. I have always been and always will be just who I am and I will never fake anything for anyone."
"I am not ever going to be a person who has a desire to expose myself more than I feel." she continued.
She expressed the same sentiments to Malibu Magazine back in July, saying "I feel like my life is exposed enough and I believe in having a private life. With paparazzi- I just don't deal with it. It surprises me that anyone would want that sort of attention!"
It's about that perfect work-life balance that is on a whole other level when it comes to being a celebrity, as there is less "down time" than you may think. Amber goes on to say that aside from keeping her life private and working hard in her career, she does not feel she should hide away from who she is just because of what the press might say about her or label her.
"I also feel I have a responsibility to not appear to be in hiding. I watched people around me succumb to hiding and hiding denotes shame. I feel, and felt, zero shame. We all love who we love; we don't choose it." she explains about the issue of her sexuality.
"If I didn't want to be scrutinized, I would have just stayed in Texas," Heard says of the hoopla. "It's way easier to do what people expect of you."
Amber told Malibu Magazine the same kinda deal: "It's impossible for me to judge myself in terms of what I am…I wouldn't want to be someone who's in this business as a commodity. I just like telling stories."
But she doesn't and she definitely won't apologize for who she is. Having a career spanning 11 years and counting, it looks like she is doing something right, and a huge part of that we think, is about Amber heard defining herself, not anyone else.
If we let others dictate who we should be, how we should act and what we should look like, we create a breeding ground for insecurity, anxiety and un-productivity. What's the point of always trying to meet everyone else's expectations? Sure our journey may look like rebellion, stupidity and a huge mistake to others, but that doesn't necessarily mean you should stop. Richard Branson didn't think twice about dropping out of school to pursue his business dreams, but imagine if he did?
As for Ms. Heard, we don't give a rats who she is dating or what she is wearing. We just like that she is forging ahead in her career and staying true to herself.


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With the Milwaukee 7 celebrating its biggest year ever of attracting economic development, Democratic Milwaukee Mayor Tom Barrett and Republican Waukesha County Executive Paul Farrow shared an actual "Kumbaya" moment.
Barrett and Farrow are two of the co-chairs for the regional group that cooperates on recruiting new employers to the area and expansion by existing employers. They were on stage at the same time Monday evening during the M7's annual meeting at the We Energies auditorium in downtown Milwaukee.
Check out the attached slideshow to see photos from the event.
First, Barrett said he was glad to see a turnaround by Farrow, who when he was elected Waukesha County executive, had reservations about the M7 as being too Milwaukee-centric. Barrett said the seven counties in the region have developed the ability to work together and pointed to the city of Milwaukee's recent agreement to supply water to the city of Waukesha.
"It shows what happens when people work with each other," Barrett said. "What we need to focus on and refocus on is how we can do what's best not only for our own communities but the entire region. Of course we want the jobs in our own city or our own county. But we also recognize that at the end of the day, we're better off having the jobs in Walworth County than in Walla Walla, Washington."
Barrett said the M7 has become very good at partnerships and then introduced "my colleague, Paul Farrow."
Farrow, who is a good half-foot shorter than Barrett then took the microphone and only half-jokingly said: "We see eye to eye on a lot of things and we see eye to eye on a lot of situations that are going on in this region."
What's going on is excitement, especially after the M7 worked closely with the Wisconsin Economic Development Corp. in recruiting Foxconn Technology Group's planned massive complex in Racine County community Mount Pleasant, Farrow said.
"I've got to tell you, yeah, I was skeptical (about M7) because it seemed to be 'Milwaukee,'" Farrow said to about 200 business and community leaders from Milwaukee and surrounding counties. "It's a big thing when you stand next to Milwaukee like this."
Farrow then gave Barrett, who remained on the stage, a quick one-arm hug, eliciting light laughter from the audience.
"But you realize the catalyst that's here and what's happening in the other six counties really drives this whole region and gives us an opportunity," Farrow said.
Foxconn clearly gave the M7 leaders something to brag about but M7 co-chairman Gale Klappa, the CEO of WEC Energy Group, also pointed to German candymaker Haribo choosing Pleasant Prairie in Kenosha County earlier in 2017. Farrow cited Milwaukee Tool's multiple expansion projects in Brookfield on the eastern end of his county.
Klappa credited Gov. Scott Walker with playing an instrumental firsthand role in recruiting Foxconn. Walker also made remarks from the stage, saying the recent news that Foxconn also will open an office in downtown Milwaukee will bring "hundreds of white collar jobs" to continue revitalizing the city of Milwaukee.


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Hi Anon,
Thank you for your post! I'm sorry to hear that your IUD has implanted itself onto your uterus. As long as you are not having adverse effects, then you're ok to wait until the 28th. You're having pain because of the location of the IUD, but not necessarily because it is causing more harm. However, if you're having severe pain related to the IUD, then you may want to call your doctors office and inform them about it. Maybe if you insist that the pain is unbearable, they may move up your date. You can also ask for them to call you if there is an opening sooner than the 28th.
Best wishes and keep up posted,
RosaJuly 2, 2011 - 7:02am


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Glucan particles (GPs) are Saccharomyces cerevisiae cell walls chemically extracted so they are composed primarily of particulate β-1,3-d-glucans. GPs are recognized by Dectin-1 and are potent complement activators. Mice immunized with Ag-loaded GPs develop robust Ab and CD4+ T cell responses. In this study, we examined the relative contributions of Dectin-1 and complement to GP phagocytosis and Ag-specific responses to immunization with OVA encapsulated in GPs. The in vitro phagocytosis of GPs by bone marrow-derived dendritic cells was facilitated by heat-labile serum component(s) independently of Dectin-1. This enhanced uptake was not seen with serum from complement component 3 knockout (C3−/−) mice and was also inhibited by blocking Abs directed against complement receptor 3. After i.p. injection, percent phagocytosis of GPs by peritoneal macrophages was comparable in wild-type and Dectin-1−/− mice and was not inhibited by the soluble β-glucan antagonist laminarin. In contrast, a much lower percentage of peritoneal macrophages from C3−/− mice phagocytosed GPs, and this percentage was further reduced in the presence of laminarin. Subcutaneous immunization of wild-type, Dectin-1−/−, and C3−/− mice with GP-OVA resulted in similar Ag-specific IgG1 and IgG2c type Ab and CD4+ T cell lymphoproliferative responses. Moreover, while CD4+ Th1 and Th2 responses measured by ELISPOT assay were similar in the three mouse strains, Th17 responses were reduced in C3−/− mice. Thus, although Dectin-1 is necessary for optimal phagocytosis of GPs in the absence of complement, complement dominates when both an intact complement system and Dectin-1 are present. In addition, Th-skewing after GP-based immunization was altered in C3−/− mice.
β-1,3-d-glucans are homopolymers of glucose that form the structural scaffold of the cell wall of medically important fungi (1). Considering the ubiquitous presence of this fungal pathogen-associated molecular pattern (PAMP), it is not surprising that host defenses have evolved to recognize and respond to β-1,3-d-glucans (2). Dectin-1, a C-type lectin highly expressed on phagocytes, including dendritic cells (DCs), macrophages, and neutrophils, serves as a pattern recognition receptor for β-1,3-d-glucans (3). Upon ligation of β-glucans to Dectin-1, a number of cellular events follow, such as phagocytosis, activation of signaling pathways and transcription factors, generation of reactive oxygen species, and release of cytokines/chemokines (4). The contribution of Dectin-1 to host defenses against fungal infections in vivo has been studied by comparing the susceptibility of wild-type and Dectin-1 knockout mice to fungal challenge. In some but not all models of mycoses, mice with Dectin-1 deficiency manifested increased mortality. For example, Dectin-1 was shown to be required for optimal control of systemic Candida albicans infection in one study but dispensable in another study (5, 6). In humans, genetic variations in Dectin-1 and its downstream signaling pathways affect susceptibility to mucosal candidiasis but not candidemia (7, 8).
Particulate β-1,3-d-glucans directly activate the alternative pathway of complement (9–11). iC3b deposited on β-glucans is recognized by complement receptor 3 (CR3; CD11b/CD18) (12). CR3 also has a distinct β-glucan binding site (13). Although complement does not lyse fungi directly, most likely because of the rigid structure of the fungal cell wall, complement plays a unique role in host defenses against opportunistic fungal infections by promoting opsonophagocytosis and by the generation of the potent chemoattractants C3a and C5a (14). Complement has been suggested to play an important role in the immune responses to β-glucans based on studies using β-glucans as an enhancement reagent for mAb-based anti-tumor treatment (15–17).
We have demonstrated that Saccharomyces cerevisiae-derived glucan particles (GPs) can be exploited to function as a vaccine adjuvant-delivery platform that elicits strong humoral and Th1- and Th17-biased CD4+ cellular responses to Ags entrapped in the particles (18). GPs are largely composed of β-1,6 branched, β-1,3-d-glucans, with ∼2% chitin and less than 1% proteins (19). GPs are recognized by Dectin-1 but are also potent complement activators (10, 18). Thus, in addition to serving as a promising vaccine platform, the size and biochemical properties of GPs make them excellent tools to dissect the role of β-1,3-d-glucans in the immune response to fungi. In this study, we used Dectin-1−/− and C3−/− mice to study the relative contributions of Dectin-1 and complement to the uptake of GPs by mononuclear phagocytes and to immune outcomes after immunization with Ag-loaded GPs.
Materials and Methods
Chemicals and cell culture media
Chemical reagents were obtained from Sigma-Aldrich (St. Louis, MO), unless otherwise noted. RPMI 1640 medium was purchased from Invitrogen Life Technologies (Carlsbad, CA). R10 medium is defined as RPMI 1640 containing 10% FBS (Tissue Culture Biologicals, Tulare, CA), 100 U/ml penicillin, 100 μg/ml streptomycin, 2 mM l-glutamine (Invitrogen), and 55 μM 2-mercaptoethanol (Invitrogen). Chicken OVA was purchased from Worthington Biochemical (Lakewood, NJ). Cells were incubated at 37°C in humidified air supplemented with 5% CO2.
Wild-type C57BL/6J mice were purchased from The Jackson Laboratory (Bar Harbor, ME). Dectin-1−/− mice were a gift from Gordon D. Brown (University of Aberdeen, Aberdeen, U.K.). C3−/− mice (The Jackson Laboratory) were bred at the animal facility at the University of Massachusetts Medical School. Both strains of knockout mice were back-crossed at least 12 generations to the C57BL/6J background. Mice were specific pathogen free, and all animal procedures were conducted under a protocol approved by the University of Massachusetts Medical School Institutional Use and Care of Animals Committee.
Glucan particles
GPs were prepared from S. cerevisiae (Fleischmann's Baker's Yeast) by a series of alkaline and acidic extraction steps as previously described (20–22). Briefly, the washed yeast cells were suspended in 1 M NaOH and heated at 90°C for 1 h after centrifugation. Hot alkali extraction was then repeated. The particles were then suspended in water at pH 4.5 and heated at 75°C for 1 h, followed by successive washes of the particles with water (three times), isopropanol (four times), and acetone (two times). GPs were labeled with dichlorotriazinylaminofluorescein (DTAF) as previously described (21). Briefly, GPs (5 mg/ml) were incubated with DTAF (0.25 mg/ml) in 0.1 M borate buffer (pH 10.8) overnight at 37°C in the dark. Unreacted DTAF was then quenched by incubation with 1 M Tris (pH 8.3) for 30 min. GPs were extensively washed in sterile water, incubated overnight in 70% ethanol, washed three times with sterile PBS, and counted.
Mouse bone marrow-derived dendritic cells
Bone marrow-derived dendritic cells (BMDCs) were generated as previously described with a slight modification (23, 24). Briefly, bone marrow cells obtained from the tibiae and femurs of 8- to 12-wk-old mice were cultured in R10 medium supplemented with 10% GM-CSF conditioned medium from the mouse GM-CSF–secreting J558L cell line. Cells were fed with fresh GM-CSF–supplemented R10 on days 3 and 6. On day 8, nonadherent cells were collected and purified with the Magnetic Cell Separation System (MACS) using CD11c+ magnetic beads (Miltenyi Biotec, Auburn, CA) according to the manufacturer's protocol. Where indicated, BMDCs were rendered unable to proliferate by incubation in RPMI 1640 containing 50 μg/ml mitomycin C for 30 min at 37°C followed by three washes with R10.
GP opsonization
Mouse blood was collected by cardiac puncture and immediately transferred to a microcentrifuge tube on ice. After incubation on ice for 1 h, the blood was centrifuged at 4°C. The serum fraction was collected and divided into two aliquots. One aliquot was kept on ice, and the other was heat-inactivated at 56°C for 30 min and then cooled on ice. GPs (up to 107 per 100 μl serum) were added to each tube of serum and incubated at room temperature for an additional 30 min. After centrifugation, the supernatant was removed, and the GP-containing pellet was resuspended in R10.
Phagocytosis of fluorescent GPs by BMDCs
BMDCs in 400 μl medium (105/well) were incubated for 1 h at 37°C in 48-well cell culture treated plates with or without laminarin (1 mg/ml). In some experiments, anti-CR3 mAbs (M1/70 and 5C6) (25) or isotype control mAbs (rat IgG2b [eBioscience, San Diego, CA]) were also added at this time. mAbs were used at a final concentration of 10 μg/ml, as preliminary experiments demonstrated that this concentration of the anti-CR3 mAb gave maximal inhibition (data not shown). After incubation, DTAF-labeled glucan particles (F-GPs; 3 × 105/well, with or without mouse serum opsonization) were added into each well. After an additional 1 h incubation at 37°C, the wells were washed three times with Dulbecco's PBS (Lonza, Allendale, NJ) to remove free F-GPs and then examined under bright field and epifluorescence microscopy to determine the percentage of the cells with one or more F-GP particles in them.
Phagocytosis of F-GPs by peritoneal monocyte/macrophages
F-GPs (107) in 100 μl saline alone or plus either 100 μl dextran (100 mg/ml, m.w. 10,000) or laminarin (100 mg/ml) were injected into the peritoneum of wild-type, Dectin-1−/− or C3−/− mice. After 1 h, 10 ml cold PBS was injected into the peritoneum and collected back. Peritoneal cells were stained with the monocyte/macrophage marker F4/80 (eBioscience) and analyzed by FACS to measure the percentage of F-GP+ cells among F4/80+ cells.
GPs containing complexed OVA (GP-OVA) were made as previously described with slight modification (18, 22). Briefly, 10 mg dry GPs was swollen with 50 μl OVA dissolved in water for 2 h at 4°C minimally to hydrate the GPs allowing OVA diffusion into the hollow GP cavity. The samples were then frozen at −80°C and lyophilized. To push hydraulically the OVA inside the GPs, the dry GP-OVA was again minimally hydrated with water for 2 h at 4°C, frozen at −80°C, and lyophilized. To trap the OVA inside the GPs, the dry GP-OVA formulations were heated to 50°C and swollen with 50 μl 25 mg/ml tRNA (derived from Torula yeast, type VI; Sigma, St. Louis, MO) in 0.15 M NaCl for 30 min. Then, 500 μl of 5 mg/ml tRNA was added for 1 h at 50°C to complete the complexation reaction trapping the OVA inside the GPs. The GP-OVA particles were washed three times in 0.9% saline, resuspended in 70% ethanol for 30 min, washed three additional times in sterile 0.9% saline, counted, and resuspended at 5 × 108 particles/ml in 0.9% saline. Aliquots were stored at −20°C until use. The typical loading efficiency was calculated to be >95% by subtracting the unencapsulated OVA in the supernatant from the initial input using a fluorescent-labeled OVA tracer.
For immunizations, wild-type, Dectin-1−/−, and C3−/− mice (8–10 wk old, 4 mice per group) received GP-OVA (5 × 107 GPs containing 3.3 μg OVA) in 100 μl by s.c. injection over the abdomen. Mice were immunized three times at 2-wk intervals and euthanized 2 wk after last immunization. Blood, spleen, and lymph nodes were then harvested for the Ab and T cell assays described in the following sections.
OVA-specific Ab ELISA
ELISA was performed as previously described with slight modification (18). Briefly, sera from immunized mice were diluted 1:40 and then progressively diluted 2-fold. Round-bottom 96-well plates coated with OVA were incubated with 50 μl diluted mouse sera at room temperature for 2 h. Wells were then washed and incubated with either biotin-conjugated rat anti-mouse IgG1 (BD Biosciences, San Jose, CA) or biotin-conjugated rat anti-mouse IgG2c (Jackson ImmunoResearch, West Grove, PA) at room temperature for 1 h. After five washes, the plates were incubated for 1 h with streptavidin-conjugated HRP (eBioscience), washed five more times, and then developed with tetramethylbenzidine solution (eBioscience). OD450 was measured on a plate reader (Molecular Devices, Sunnyvale, CA). The Ab titer was defined as the dilution factor that was 2-fold greater than the inflection point. Each dilution of serum was tested in duplicate.
T cell proliferation and ELISPOT assays
The assays were performed as previously described (18). Briefly, CD4+ T cells were purified from combined lymph node cells and splenocytes using negative selection CD4+ T cell isolation kits (Miltenyi Biotec, Auburn, CA) according to the manufacturer's protocol. To measure T cell proliferation, purified CD4+ T cells (105/well) were incubated in triplicate or quadruplicate for 4 d with mitomycin C-treated BMDCs (104/well) and the indicated stimuli in round-bottom wells of 96-well plates containing 200 μl R10. Cells were pulsed with [3H]thymidine (1 μCi/well; PerkinElmer, Boston, MA) for 24 h prior to harvest. Lymphoproliferation was then determined by measuring [3H]thymidine incorporation with a β counter (Wallac 1450 MicroBeta). For the ELISPOT assay, 96-well Multiscreen HTS plates (Millipore, Billerica, MA) were coated with capture mAbs directed at murine IFN-γ, IL-4, or IL-17A. Purified CD4+ T cells (105/well), mitomycin C-treated BMDCs (104/well), and the indicated stimuli were incubated at 37°C for 42–45 h. Samples were run in duplicate except for one experiment that was run singly. Plates were then developed with 5-bromo-4-chloro-3-indolyl phosphate/NBT solution and the number of spots enumerated using an Immunospot ELISPOT reader (Cellular Technology, Shaker Heights, OH).
Data were analyzed and figures prepared using GraphPad Prism Software. For comparisons of three or more groups, the one-way ANOVA with the Tukey multiple comparison was performed. Experiments comparing two groups were analyzed using a two-tailed unpaired Student t test with Bonferroni's correction applied for multiple comparisons. Significance was defined as p < 0.05.
Role of Dectin-1 and complement in the phagocytosis of GPs in vitro
In this study, we confirmed our previous finding that uptake of unopsonized fluorescent-GPs by wild-type murine BMDCs is dependent on Dectin-1 and could be inhibited by low m.w. Dectin-1 antagonist laminarin (21) (Fig. 1A). However, particulate β-1,3-d-glucans are potent complement activators (10). Therefore, we studied uptake under conditions where an intact complement system was present, as would be expected to occur under typical in vivo conditions. After GPs were opsonized with fresh mouse serum from wild-type mice, uptake was slightly increased and was no longer inhibited by laminarin (Fig. 1A). Destruction of complement activity of mouse serum by heating to 56°C for 30 min restored the ability of laminarin to inhibit Dectin-1–mediated uptake of GPs (Fig. 1A).
When the same experiments were performed with BMDCs from Dectin-1–deficient mice, a different pattern emerged. The critical role of Dectin-1 in facilitating phagocytosis of unopsonized GPs by BMDCs was recapitulated. Under conditions of no opsonization, almost no uptake of GPs by Dectin-1−/− BMDCs was observed (Fig. 1B). However, when GPs were opsonized with fresh mouse serum, robust uptake was seen, even in the presence of laminarin. This increased phagocytosis was not seen if the serum was heat inactivated, thereby inactivating complement. Finally, when GPs were opsonized with serum from C3−/− mice, the full effect of laminarin upon BMDC uptake of GPs was apparent (Fig. 1C) because the effect of laminarin was not masked by the presence of active complement component 3 (C3). Under all opsonic and non-opsonic conditions, careful epifluorescent microscopy confirmed that the vast majority of cell-associated GPs was internalized by the BMDCs (data not shown). Taken together, these results suggest that both complement and Dectin-1 contribute to the uptake of GPs in vitro.
Involvement of CR3 in the ability of serum to facilitate GP phagocytosis
Activation of complement by GPs results in deposition of iC3b on the surface of the particles (10). As CR3 (CD11b/CD18) serves as the major receptor for processed complement component iC3b (12, 13), we next examined the effect of anti-CR3 mAbs on BMDC phagocytosis of GPs. In preliminary studies, we had demonstrated strong expression of CR3 on BMDCs (data not shown). In the presence of fresh wild-type mouse serum, anti-CR3 mAbs had a modest, but significant, inhibitory effect on GP uptake (Fig. 2B). This effect was enhanced when β-glucan receptor binding sites were inhibited with laminarin. These results suggest that CR3 on BMDCs mediates uptake of serum-opsonized GPs. Although CR3 has a direct β-glucan binding site (13), the anti-CR3 mAbs had no effect on uptake of unopsonized GPs or GPs incubated with heat-inactivated mouse serum (Fig. 2A, 2C), suggesting uptake through CR3's direct β-glucan binding site is minimal.
Roles of Dectin-1 and C3 in mediating GP uptake by peritoneal cells
To study the roles of Dectin-1 and C3 in vivo, we examined the phagocytosis of GPs by peritoneal monocytes/macrophages, as defined by positive staining for F4/80+, after intraperitoneal inoculation. For these experiments, some mice also were injected with the soluble β-glucan receptor antagonist laminarin. It has been shown that laminarin does not activate the complement system (10). Dextran, a soluble α-glucan, served as a negative polysaccharide control. Neither dextran nor laminarin had an effect on F-GP phagocytosis in wild-type mice compared with mice receiving F-GPs only (Fig. 3). Compared with wild-type mice, no significant differences in the percentages of F4/80+ cells containing associated GPs could be found in Dectin-1 knockout mice, regardless of the presence of laminarin (Fig. 3). However, significantly reduced GP uptake by peritoneal monocytes/macrophages was observed in C3−/− mice; this was reduced further by the addition of laminarin (Fig. 3). These results suggest that although both Dectin-1 and complement receptors contribute to recognition of particulate β-glucans in vivo, complement plays a dominant role.
Contributions of Dectin-1 and C3 to immune responses after GP-based vaccination
We have demonstrated that immunization of mice with Ag-loaded GPs elicits both strong humoral and Th1/Th17-biased CD4+ T cell responses (18). To assess the relative contributions of Dectin-1 and complement, anti-OVA Ab development, CD4+ T cell proliferation, and T helper ELISPOT assay were compared in wild-type, Dectin-1−/−, and C3−/− mice, each immunized with GP-OVA. IgG1 and IgG2c anti-OVA Abs were induced at similar titers in all three mouse strains (Fig. 4A, 4B). CD4+ T cells from C3−/− mice proliferated slightly more than those from wild-type mice, both in response to OVA and to the mitogen Con A (Fig. 4C). Although no significant differences were seen in the number of OVA-specific IFN-γ– or IL-4–producing CD4+ T cells among the three mouse strains, OVA-specific IL-17A–producing CD4+ T cells from C3 knockout mice were significantly reduced compared with those from wild-type or Dectin-1−/− mice (Fig. 4D).
The immunological consequences of ligation of β-glucans with Dectin-1 and other β-glucan receptors have received considerable study in the past decade (reviewed in Ref. 26). However, β-glucans are also potent alternative complement pathway activators (9–11). Thus, to formulate an integrated model of how β-glucans interact with the immune system, the role of complement must be taken into account. In this work, we studied the relative contributions of Dectin-1 and complement to immune responses to GPs. As GPs do not contain mannans, lipids, or proteins, their use allows the dissection of responses to particulate β-glucans without the confounding contributions of these other ligands. We found that complement facilitated the phagocytosis of GPs both in vitro and in vivo. More importantly, Dectin-1 was dispensable for Ab and CD4+ T cell responses to Ag-loaded particulate β-glucans in vivo. In contrast, although complement was redundant for some immune responses, optimal CD4+ Th17 responses required an intact complement system.
We previously demonstrated that Dectin-1 was indispensable for the phagocytosis of GPs by BMDCs in vitro (21). However, those studies used tissue culture media containing heat-inactivated FBS and thus did not take into account that particulate β-1,3-d-glucans are potent complement activators (10). Indeed, when fresh serum was used to opsonize GPs, phagocytosis by BMDCs proceeded, even if Dectin-1–deficient BMDCs were used or if β-glucan receptors were blocked with laminarin.
Opsonization of GPs with complement-sufficient serum results in dispersal on the GP surface of iC3b (10). Whereas some DC populations do not express the iC3b receptor, CR3, BMDCs do, and blocking of CR3 with anti-CR3 mAbs inhibited the uptake of opsonized GPs. This effect was more profound when β-glucan receptors were blocked with laminarin. However, some phagocytosis was still observed that could have been mediated by the DC cell surface protein, CD11c/CD18, which also binds iC3b (27).
In some experimental systems, Dectin-1 is required for β-glucan–induced Th17 development in vitro (28–30). In addition, recent in vivo studies show that Dectin-1 is essential for the adjuvant effect of the bacterial β-1,3-d-glucan, curdlan, and the anti-tumor activity of particulate β-glucans (30, 31). However, in our studies, wild-type and Dectin-1−/− mice immunized with GP-OVA developed similar OVA-specific Ab titers, CD4+ T cell proliferative responses, and CD4+ T cell skewing. The reason for this discrepancy is speculative but may be explained by differences in how the Ags were delivered. In our system, OVA was encapsulated inside of GPs and thus the Ag and β-glucan were targeted directly to the same compartments within APCs. In contrast, in the aforementioned studies, the Ags and β-glucans were admixed and therefore would not necessarily traffic to the same intracellular compartment. Colocalization of Ag and PAMPs has been shown to increase the efficiency of the T cell response (32) and may thereby diminish the need for Dectin-1. In addition, in the absence of Dectin-1, complement receptors and other β-glucan receptors, such as the scavenger receptors SCARF1, CD36, and CD5, may compensate for the activities of Dectin-1 (33-35). Indeed, β-glucan signaling through CD36 has been shown to induce cytokines (34).
Although the complement system was originally thought to contribute only to innate immunity against pathogens, more recent studies support the concept that complement activation can instruct B and T cell development (reviewed in Refs. 36, 37). Complement activation by GPs results in the generation of the cleavage products C3a and C5a (10). Interaction of these chemoattractants with their cognate receptors may influence Th17 development. In models of asthma and infection, mouse strains deficient in C3aR1 have impaired CD4+ Th17 cell responses, whereas C5a receptor knockout mice mount enhanced IL-17A responses (38–40). The importance of the C5a–C5aR pathway in Th17 cell development also has been demonstrated in an autoimmune arthritis model (41). C3 is central to all three complement activation pathways, and C3 deficiency will generally result in the loss of complement function. Notably, however, in the absence of C3, thrombin can substitute as a C5 convertase to generate C5a, albeit at reduced levels (42). Future studies will be needed to dissect the contributions of C3a and C5a to the Th17 responses observed after immunization with Ag-loaded GPs. Additionally, the relative contributions of the alternative and classical pathways of complement activation needs delineation. Although GPs directly activate the alternative pathway (10), recent data demonstrating that mice have natural IgM Abs against β-glucans suggest that the classical complement pathway could also be activated by GPs (43).
How the immune system specifically responds to particulate β-glucans is difficult to reconcile with models that use live fungal challenges. In addition to β-glucans, fungi have multiple other PAMPs, such as mannans, that are innately recognized by the host immune system (2). In addition to serving as a vaccine platform, Ag-loaded GPs serve as a tool to study how β-glucan recognition contributes to immune responses to fungal Ags. Our data suggest a redundant role for Dectin-1 in the generation of systemic CD4+ T cell and Ab responses to Ags within particulate β-glucans. This redundancy appears to be explained by the ability of complement activation by β-glucans to license immune responses to associated Ags. However, it will be important to examine whether Dectin-1 is required for optimal mucosal immune responses, particularly given the association of mutations in Dectin-1 genes with mucosal candidiasis (7). In summary, our data suggest a dominant role for complement and a redundant role for Dectin-1 in both phagocytosis of GPs and CD4+ Th17-skewing after GP-based immunization.
The authors have no financial conflicts of interest.
This work was supported by Grants RO1AI025780 and R21AI093302 from the National Institutes of Health.
Abbreviations used in this article:
- bone marrow-derived dendritic cell
- complement component 3
- complement receptor 3
- dendritic cell
- dichlorotriazinylaminofluorescein
- DTAF-labeled glucan particle
- glucan particle
- GP containing complexed OVA
- pathogen-associated molecular pattern.
- Received February 22, 2012.
- Accepted May 3, 2012.
- Copyright © 2012 by The American Association of Immunologists, Inc.


text: Family engagement in the school has been shown to be beneficial to both the school and the student. There are many ways parents can be involved at their child's school, however, what opportunities are there for parents who work or don't speak English? The Academic Parent-Teacher Teams (APTT) addresses these issues. Implemented in a high ELL and FRL school district in Phoenix, AZ, the APTT replaces the traditional parent-teacher conferences with three classroom team meetings, and one individual parent-teacher meeting. This program seeks to engage parents in their children's learning by working with them to strengthen and support their child's academic skills outside of the school. Parents become familiar with their child's assessment data, with help from the teacher, and they also practice activities that can be done with their children at home. Parents are able to network with each other, have a complete understanding of where their children are academically, and learn techniques to work with their children. Evidence of effectiveness include an increase in the number of teachers participating in this program, an increase in both parents attending the team meetings and understanding their child's academic performance, and short-term academic gains in APTT classrooms. For more information on this new way of parent-teacher conferencing, see http://hfrp.org/publications-resources/browse-our-publications/academic-parent-teacher-teams-reorganizing-parent-teacher-conferences-around-data.


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Book Details
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London. Charles Daly. 1837. pp. xvi, 432. Frontis, engraved title & 17 plates. 32mo. Full morocco with gilt decoration. All edges gilt. pp 191 - 194 top corner worn away not affecting text. The engraved title shows the publisher as Charles Mason and is undated, the printed title shows Charles Daly as publisher & is dated. William St. Clair in The Reading Nation in the Romantic Period in Appendix 11 - Pirate and radical publishers and publications - Byron's Don Juan p690 lists 1837. London: Charles Mason. 32mo. Extremely small type scarcely readable in a fat little volume. Numerous engraved illustrations & 1839. Charles Daly. A version of Mason's edition of 1837. Other versions have been found dated 1839, 1849 and undated. This would appear to be an earlier Daly edition than listed by St Clair. It is quite sweet.
Order Number: 10384
Website by Xtreme Multimedia


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Author(s): L. Randy Schmidt
Karen Carpenter was the instantly recognisable lead singer of the Carpenters. The top-selling American musical act of the 1970s, they delivered the love songs that defined a generation. Karen's velvety voice on a string of 16 consecutive Top 20 hits from 1970 to 1976 - including "Close to You", "We've Only Just Begun", "Rainy Days and Mondays", "Superstar", and "Hurting Each Other" - propelled the duo to worldwide stardom and record sales of over 100 million. Karen's musical career was short - only 13 years. During that time, the Carpenters released 10 studio albums, toured more than 200 days a year, taped five television specials, and won three Grammys and an American Music Award. But that's only part of Karen's story. As the world received news of her death at 32 years of age in 1983, she became the proverbial poster child for anorexia nervosa. Little Girl Blue is an intimate profile of Karen Carpenter, a girl from a modest Connecticut upbringing who became a Superstar. Based on exclusive interviews with nearly 100 friends and associates, including record producers, studio musicians, songwriters, television directors, photographers, radio personalities, classmates, childhood friends, neighbours, personal assistants, romantic interests, hairdressers, and housekeepers.
' - thorough and affectionate biography of a singer who's been constantly undervalued by the music industry.' MOJO 'Schmidt cannot be faulted - carefully factual, sensitively pitched book.' The Word
Randy L. Schmidt teaches music in the Dallas/Fort Worth area. He compiled and edited Yesterday Once More: Memories of the Carpenters and Their Music and served as creative consultant for several television documentaries on the Carpenters, including E!'s True Hollywood Story, A&E's Biography, and VH1's Behind the Music.


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A Day in the Neighborhood
It's a Thursday evening. I just came inside from doing yard work with at least 7 of the neighborhood kids who were taking lazy rotations to 'help' me shovel and move dirt. While we work, we take breaks to watch about a half dozen other neighborhood boys and girls take trick shots on the new basketball court. Others sit out front talking to my wife about grades, birthday parties and summertime plans. Our kids are making the rotation at will between friends, daddy's work, basketball, biking, and mom. This is the Antioch house, where we partner and live to make disciples with neighborhood youth: empowering the leaders of tomorrow. We currently live here and hold weekly meetings for meals, bible study and fellowship with 20+ of our neighborhood youth.
Earlier today, I led a team of 7 out to pray with our neighbors 4 blocks East at the 810 House. Every week we meet to intercede for our neighbors and then head out in teams to share the Love of Christ. My team met three young ones who had never heard the Gospel before. I explained the whole Bible story as best I could and all 3 asked Jesus to live in their hearts. (Try explaining the Bible story to someone who's never heard of Jesus…it's both refreshing and challenging finding words and stories that aren't 'churchy') The 2 other teams prayed with many others as well, bringing the total to 4 who prayed for salvation today.
What I love about neighborhood evangelism is the fact that we have a greater chance of staying in touch. We want to form relationships that will last an eternity. I was able to chat with the kids' grandma and invite them to our Thursday night programming with Antioch. We had Action Bibles and Jesus Story Book Bibles to give them, and 2 homes within 4 blocks to invite them to. With each significant encounter, we ask permission to record their address and contact info for continued follow up.
There's never any guarantees that we'll see the fruit of our labor during this lifetime; but Christ's promise remains the heartbeat of our days here: "remain in me and I will remain in you…and you will bear much fruit. Fruit that remains." As we are faithful to obey Christ and stay rooted and grounded in His love, He will bear fruit that will last an eternity.
Things aren't always this beautiful.
This past month, a neighbor boy had a gun pulled on him. He hasn't really wanted to talk about it, but Miah was able to spend some deep time ministering with family and neighbors. She sat for a couple hours in our kitchen with 2 of the neighbor girls in particular; sharing life experience and prayer.
Neighborhood violence has been on the rise as the weather warms. It seems every week there are more stories of people effected by hate. The Star Tribune recently reported that 120+ reported shootings have happened this year to date. A grandma was hit several blocks over by crossfire and died last week. There is a basic understanding among neighbors that this summer is going to be violent as gang wars escalate.
I've been praying about how the Holy Spirit might want us to respond, and felt His leading to develop the "Salt and Light Campaign." (www.thelightofnorth.com anyone can sign up to follow/participate.) The basic approach comes from an understanding that as "ambassadors of Christ" and "ministers of reconciliation", our prayers matter and influence our environment. "we do not wrestle against flesh and blood, but rulers, powers and authorities," the Bible says. "Our weapons have divine power to demolish strongholds.." "the prayers of the righteous are powerful and effective…" I want to do as Hezekiah did; spread out these bad reports before the Lord and ask for a monumental move of the Holy Spirit. Only He is able to bring peace. Many have tried in their own strength to solve our problems. We need God.
This is a multi-denominational strategy to cover every day from mid-June to mid-August in corporate prayer (salt) and blessing (light). We have over 20 neighborhood churches and organizations so far that have 'adopted' days to hold neighborhood prayer meetings, followed by an act of blessing for our neighbors. The blessing could be anything from popsicles to street witnessing, but the point is to love our neighbors well and establish relationships that will lead to the healing of our community. Each days' event will be posted on the website, and believers from all the local churches will be notified and encouraged to come together for prayer.
It's going to be awesome!
NEEDS and UPDATES
For the Salt and Light Campaign to go well, I do need some admin support. If you or anyone you know would be willing to donate 5-10 hours per week in data entry and phone work, please let me know![firstname.lastname@example.com or 612.750.6994] (WordPress knowledge is a plus!)
810 Project:
We had an amazing team of 4 come all the way down from Warroad, MN last weekend. They accomplished in 1 day what would have taken me a month. They hung doors and placed trim, among many other things. Thank you Woodland Team!!!
I still have several 'small' jobs to do around the house in order to pass inspection. If you know anyone who would be handy with a paint brush or grout, I would love to meet them!
In addition, we've had a landscape artist step forward with an amazing plan for the yard. It will be tremendous asset to the neighborhood with a prayer garden and peaceful walkway. However, we need materials donated and possibly some heavy equipment to fulfill this dream. Could you refer me to a landscaping company who might be interested in helping us out?
Finally, Summer is here!
As we approach the summer with our own kids, Miah and I have committed to include at least 1 neighborhood child in the activities that we enroll our kids in (swimming, track, ect). This is our basic approach to discipleship: including our neighbors in the day to day activities that we do; sharing the Love of Christ tangibly and consistently. These aren't only opportunities for neighbors to participate and learn new skills, it is an opportunity for us to minister on a deeper level with each family.
However, some of these fees are expensive so if anyone would be willing to donate to cover some of these costs we would greatly appreciate it.(www.damascusway.com and click on donate. Choose 'the810Project' from the drop down.)
Mostly, we covet your prayers. We are in great need of more intercessory warriors. If you understand the power of prayer and would be willing to join with us in contending for the healing of North Minneapolis, the strength of our marriage, family and ministry, would you please let us know by email or text? We know that nothing good happens without prayer. Prayer is where the work is done and the battle is won.
To sign up for our intercessory team, simply send us an email at:email@example.com
Ongoing involvement:
This summer, if you'd like to 'taste and see' what we do at the 810 Project we'll have ample opportunities for volunteers with the Salt and Light Campaign. Let us know if you'd like to come over for a visit:)
Also, our friends at Trinity Works are heading up a city wide event called "Love Twin Cities". It a powerful approach to evangelism; combining 24 hours of prayer and worship, with 24 hours of teams going out to witness. For more info or to sign up, go to www.lovetwincities247.com
As always, thank you so much for sending us here! I'd like to leave you with 1 last story that really blew me away and encouraged me. I hope it does the same for you:
I have been walking with 'A' for about 2 years now. He's not a man that you would look at and say, "wow, he's a really great Christian!" He's very rough around the edges and we've been working off and on about specific character issues. Anyway, he's got a great heart for his family and is the most giving man I've ever met.
This past weekend, he got in an argument with his oldest daughter and some very hurtful words were spoken. He left the house in a bad mood and began driving aimlessly. The meditation of his heart was basically teetering on leaving or minimizing his relationship with his family.
In his state of mind, he apparently was following a vehicle a bit too close. At the next turn, the driver of the other vehicle got out and approached A's car. The older man asked, "Why were you following me so close?" "I apologize," said A. "I didn't realize I was so close to you."
The old man continued, "That's not really why I came over here. I came to tell you that your family sees the way you've been acting and they need you to love them. I knew your dad when he was a sheriff down south. I know you. You need to love your family."
Now, A's dad was a sheriff when A was 4 years old. For this man to recognize A, who is now in his 40's, from his rearview mirror and put A's 4 year old face on his 44 year old body hundreds of miles and years removed from their hometown has got to be the most impossible thing I have ever heard of.
To me, this has to be an angelic invitation. Jesus saw what was going on in A's heart, and sent a messenger to intervene his life. "A" called me moments after this encounter and was flabbergasted. I am too. The fact that Jesus loves us so much that He would interrupt and intervene our day to day activities is something we forget and overlook often. A's story is a great reminder to me that: 1) God is real. 2) God is Love. 3) God sees what is hidden. 4) God is greatly concerned about the attitude of our hearts.
How is your heart today? Are you in a growing and loving relationship with Jesus? My prayer for you is that you would find the Love of Christ, and be so captivated by who He is that everything else would become worthless. Jesus is worthy of everything, and Jesus is faithful.
May the Lord bless you and keep you, as we strive together to do His will.
the Daniels


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The Psychic readings below are from the show link above. Join me every Wednesday from 4-6pm PT for live readings using my unique method of connecting you with your Spirit Guides for a personal reading that is ALL YOU!
The mystical tarot card has come a long way from its humble origins. In the field of psychology, Carl Jung (1875-1961) used tarot cards in analyzing the Subconscious. I use this same technique today on my radio show.
Tarot cards were originally used to play a card game that was very similar to bridge. As with the Tarot cards today, 21 of the special cards served as permanent trumps. These could be played regardless of what suit was led, and outranked all the ordinary cards just as the Trump cards of the Major Arcana do today. The game became known as the Game of Triumphs and was popular especially among the upper classes of society. In my radio show I use both a deck of playing cards and the Tarot cards for more accurate readings.
On my radio show I use numerology, colors, seasons, realms,directions, astrology tand much more hrough birthdates for more accurate readings of both a deck of playing cards and the Tarot Cards.
Each radio show begins with a protection blessing. If you are reading this blog you may do the same by cocooning yourself in protective mirrored light that only allows that which is of the highest and best to enter into any Tarot information. Everything else is reflected back from whence it came. We wish it so and therefore it is.
In this blog, I have the time to add additional information concerning the personal readings including synchronicities that become apparent during the show.
What are synchronicities? By definition a Synchronicity is a noun, an apparently meaningful coincidence in time of two or more similar or identical events that are causally unrelated. As you read this blog you may see even more. Synchronicities in the reading will often mirror what is happening in your life. This is because we are all connected by the Greater Oneness of Life. There are no accidents, only accidently on purposes. The number synchronicity in these readings is 3.
During the show, I introduce callers to their personal Conventional Playing Card and Tarot Divination Card by using their birthdates. I connect these with numerology and astrology. These are then used for readings and dream interpretations. If you share a birthday with any of these callers you may be reading about yourself.
After the show, I post the readings and additional pertinent information that correlates with the reading on my blog. Callers are identified by their name and area code.
Below is the Rune Chart used in the readings .
Becky called in for a reading.
Her Date of Birth (DOB) is Jan 24 and that makes her a 3 of Diamonds = 3 of Pentacles
People who are Pentacles = assess the world around them on the level of the five senses because they are so planted in the earth realm. They can be very attached to money and possessions and often judge their success and the successes of others by their possessions.
People who are 3s= possess the essence of the trinity: Mind, Body, Spirit-Father, Son, Holy Ghost. Three is a number of great strength because it represents the threefold nature of the one god. In scripture it stands for a completed period of time. Peter denied Christ three times, Jonah was in the belly of the whale for three days.
People who are 3 of Pentacles= Your life is about gain in finance during this lifetime and you often use artistic skills to achieve this. Your inner beings who make up your complete-self, that goes beyond Id , Ego and Super Ego in this lifetime are different and diverse yet compatible. Connect and work with them through your dreams and meditations so you can continue to work together to achieve your Life Goals and Life Purpose.
Becky wants to know what her Near Future holds for her. Using colors and numbers she chooses the Major Arcana Tarot Card 20. The Roman numeral for 20 is XX=YOU ARE HERE!
This is immediate validation from her Spirit Guides that she has chosen the correct card.
XX is The Judgment Card= A renewal and rebirth of plans. The important words that go with this card are FORGIVENESS & IMPROVEMENT. By forgiving not only yourself but others in your life, your life will improve. Don't forget the lesson you learned. Forget the pain. Forgive the person, the incident and yourself for your reactions, and move on. The lesson you learned is the silver lining to that dark cloud.
Suzanne Strisower chose the following Runes for Becky's reading.
1) Flowering= grounding in order to bring to fruition.
2) Co-creative rune= energy flowering out= CLAIM WHO YOU ARE.
3) Fire Rune= be true to your passion and great-spirit.
4) Moving through Rune= transition in your thought process.
After the reading Becky shared with us that she is moving out of an abusive relationship that had kept her from her son. Forgiveness is an issue but she will work on it. She felt her Tarot card described her perfectly.
Tune in for more readings in Part II and III of this radio show.
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Crispy Crunchy Parmesan Potatoes
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4 medium potatoes, scrubbed (not peeled)
4 tablespoons olive oil
¼ teaspoon McCormick's garlic powder, onion powder & pepper
½ teaspoon parsley
Morton salt to taste
4 tablespoons fresh parmesan cheese, divided
Preheat oven to 450 degrees and line a pan with parchment paper.
Slice potatoes ¼" thick and toss with olive oil seasoning and 2 tablespoons of parmesan cheese.
Bake in a single layer about 30 minutes or until browned, flipping potatoes after 15 minutes.
Once browned, top with remaining 2 tablespoons parmesan cheese and bake an additional 5 minutes or until cheese bubbles and browns.
Source: Allrecipes.com
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Star Wars icon Carrie Fisher and her late mother Debbie Reynolds will reportedly be laid to rest later this week.
The Fisher-Reynolds family will be holding a private ceremony in Beverly Hills, California on Thursday (January 5) in celebration of both actresses' lives, a family source told The Hollywood Reporter.
"I'm not sure what they're calling it - a funeral or a wake - but it will be Thursday at the house," this friend said. "It will be exactly what they both wanted, to be together."
The family announced last week that they would be holding a joint service at some point in the future for both Carrie and her mother Debbie, who tragically died only hours apart just after Christmas.
In his first interview since the tragedy, Carrie's brother Todd Fisher told ABC's 20/20 that the deaths of his two loved ones was "horrible" and "beautiful" all at once.
"From the family's perspective, this is Debbie's destiny," he explained. "She didn't want to leave Carrie and did not want her to be alone.
"My mother loved helping her and watching after her… I think she'll be of great assistance in heaven with Carrie."
Debbie apparently died from a stroke less than 24 hours after her daughter Carrie passed away from suspected cardiac arrest in a Los Angeles hospital.
The Star Wars actress's daughter Billie Lourd - who is a cast member on Scream Queens - reached out to fans earlier this week to thank them for their outpouring of love and support as she grieves.
"Receiving all of your prayers and kind words over the past week has given me strength during a time I thought strength could not exist," Lourd wrote.
"There are no words to express how much I will miss my Abadaba and my one and only Momby. Your love and support means the world to me."
Tributes from fans and famous friends continue to pour in as the world says goodbye to two Hollywood legends.
Want up-to-the-minute entertainment and tech news? Just hit 'Like' on our Digital Spy Facebook page and 'Follow' on our @digitalspy Twitter account and you're all set.


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JAMMU: Minister for Education, Mr. Naeem Akhtar asked the teaching fraternity to imbibe quality education along with moral values to the students for their bright future.
The Minister said this while interacting with the teaching staff of Shri Ranbir Singh Higher Secondary School (SRHSS) here this evening.
Minister of State for Education, Mr. Priya Sethi was also present on the occasion.
The Minister said being the oldest school of the State established in 1872, this prestigious school of Jammu has produced number of leaders IAS/IPS officers, famous Doctors and Engineers.
Mr. Naeem said that this school would be developed as a model school by providing modern infrastructure besides innovative laboratories. He said computer lab of the school would be also upgraded besides library would be provided knowledgeable books on different topics for the students.
The Minister said that the Government is expending huge amount on the education sector for providing quality education to the students adding that it is responsibility of the teaching community to pay special heed on the teaching of the students for achieving quality results in government educational institutions.
Director School Education, Jammu S. Simrandeep Singh was accompanied by the Minister during the visit.
The Principal of School, Mr. J. S Manhas gave detailed resume of the working of the school.


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Out there in the market, you will find many unique antique gifts that make unique collectibles people should consider most The key to buying these gifts is going for something that promises to retain its value for an extended period. Below are some top unique antique gift collectible forms that you should consider most;
The bracelets:
The bracelets are among unique antique gifts that have turned popular to many people out there. They normally come in different sizes and forms. You will find some coated with vintage gemstones and others with quality diamond. It's you the buyer to choose the one that you feel is right for you.
There exist different sets of beautiful earring sets out there, but then, settling at a rare antique earring set is never a joke, and this is among the most luxurious gifts you would have bought. Whether you like unique earrings that contain vintage pearls or the diamond-studded ones, you will find the right thing for you
Antique watches:
These have from the past been the most unique antique kind of gift preferred by most people. They turned out to be popular since they are hard to find in a better working condition and very unique in a way. Though, unlike other gifts that contain mechanical parts that can get damaged over time, they tend to stay quite longer like others with such parts.
Antique necklaces:
These are actually among the finest pieces of gifts that you will get out there to purchase. The best part of these unique antique gifts is that they are now growing to be a norm to world celebrities as they wear them mainly to accessorize their ensemble.
Fashion rings:
Before we end our list we should not forget about the fashion rings as members of some unique antique gifts we have in place. You can find some amazing forms of these gift items to add on your entire collection depending on the center stone that has been used to create it A fashion ring made from a rare stone like for instance from emeralds can be a wonderful choice you would have made.
As these gifts keep on becoming popular all year round, different ways have been put in place to accessorize to help buyers make the right choice as possible. To make the selection process simpler, here is a guide to those who are out there buying one of these gifts so that they can make the right choice;
1) To begin with, you should investigate the selling store you intend to make your purchase from. There are in place methods that will help buyers make their right gift choices. So, before you get out looking for unique antique gifts, consulting a pro dealer in these items will help you pursue easily in what you want to do.
2) The next thing is to take time to determine the style of gift you need to buy. You should know that some craftsmen can at time replicate the look of a particular piece of a gift as there are people who will be interested with just the looks of the particular item they intend to buy never minding their actual antique. So, it is important you choose a gift that is made from a popular pro in the market.
You should avoid rushing into buying any gifts until you have fully made the mind of the specific item you need. To add on this, determine right if the gift you choose matters whether they have the quality to be called real antiques or not
3)A unique antique gift valuer can provide you with much detailed appraisal of the kind of items you intend to choose and prove to you whether they are made from an authentic material you needed and also if they are truly the unique gift you need. To settle at an authentic unique antique gift, you will need the help of a credible dealer to look on your behalf the gifts that are in the market.
Reading all through this content all time will provide you with an idea of available unique antique gifts in the market and tips that will help buyers make the right selection.


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The other day, I was mixing a vodka and tonic, enjoying the civilized tinkle of ice in the glass and the refreshing scent of lime. For some reason, the sharp lime fragrance reminded me of the cocktails my parents used to have with friends of theirs, the Kixmillers. We often stopped off and stayed overnight with them, breaking up the epic annual summer trip from New York State to Maine.
The Kixmillers lived on and owned an island in Lake Champlain. Even as a child, this impressed me. Dr. K would pick us up in town and take us to the island in his motorboat. Apparently boat is still the only way to reach the lovely island with the unlovely name of Fish Bladder Island.
I curiously Googled the island and discovered that it is for sale for nearly $2 million dollars. I was surprised to see that the house I remembered, with its lovely wood paneling, gracious porches, and, most impressive to me, the wraparound upstairs gallery where the many bedrooms were located, is long gone. In its place is a new house:
which bears an uncanny (although luxe version) resemblance to my current home:
In the old days, the grown-ups would sit on the porch overlooking the lake and sip their gin and tonics in the evening while we played on the lawn and in the lake (where we acquired leeches, removed by salt after much squealing). Dr. K raised the flag – I can see no sign of the flagpole in the listing – every morning, and in the evening, he lowered it to the sound of "Taps", finishing off the ceremony with firing a very small cannon. You can see why this place impressed itself so strongly in my memories.
Sometimes I think I'd like to go back and see the house where I grew up, and my grandparents', and revisit our old stomping grounds in Maine. I haven't been to Bar Harbor in 20 years, and found it refreshingly unchanged at that time, but perhaps it's better to remember things the way they were.


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First WWS of 2014
Kicking off Wycombe Web Scene for the first time in 2014, and hoping to chat to you guys about what'd be cool to do in the coming year. Shall we keep it the same (chats in pubs), or shall we go for something with a couple of speakers (like Geek Night or Breaking Borders)? Looking to make this what you all want! Feel free to wait till the night to talk to me about it, or leave your suggestions in the comments
Wycombe Web Scene is an opportunity for designers, developers and other web folk in the High Wycombe area to meet others over a few drinks, whether it be alcoholic or non. We meet in The Bootlegger in Wycombe, which has a BYO food policy, so you can bring something to eat, and has a nice selection of beers, wines and soft drinks.
If you have any suggestions for making out meetup better, then feel free to drop either @WycombeWebScene or @lurkmoophy a line on Twitter.
An event page by Luke MurphyWearmouth
Made with love in London
We ask for your email address so that we and the attendees have a way of contacting you.


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Fha Loan Downside
Downside: The Disadvantages of FHA Loans for Home Buyers – Downside: Possible Disadvantages of Using an FHA Loan. There's an upfront mortgage insurance premium (MIP), which is usually 1.75% of the base loan amount. Borrowers must also pay an annual premium, which can vary. The annual premium for most FHA borrowers is 0.85% of the base loan amount. These premiums can be rolled into the loan,
Downside: The Disadvantages of FHA Loans for Home Buyers – Downside: Possible Disadvantages of Using an FHA Loan. Before we discuss the downside of this program, let's briefly look at the upside. FHA loans are well suited for borrowers who have little cash saved up for a down payment. That's because the program offers a 3.5% down payment option for borrowers.
Guaranteed Home Sale Program Federal Government Guaranteed Home sale program federal government: full version. – Guaranteed Home Sale Program Federal Government: full version free software download.. (gsa). fas procurement solutions to meet agency needs for guaranteed home buyout programs. government links. Federal Travel. A loan guarantee, in finance. Government loan guarantees.Select Funding Interest Rates LoanBuilder: Build Your Own Business Loan | Small Business Loans – Build your business through fast and simple funding today with a business loan from LoanBuilder.. In addition to the fixed fee (total interest charge) for the loan , the only other cost is a $20 Returned Item Fee that is. Select a shorter term.
BALANCE: Advantages and Disadvantages of FHA Loans – Advantages and Disadvantages of FHA Loans: If you're looking to buy a home, you may have been attracted to the loosened approval standards that can come with a government-backed Federal Housing Authority (FHA) loan. But before jumping into an FHA mortgage, it's important to understand the possible benefit and drawbacks. Potential advantages
FHA currently has 4.8 million insured single family mortgages and 13,000 insured multifamily projects in its portfolio. Note that the FHA has maximum mortgage limits based on the place you live. To find out how much house you can buy with an FHA loan use LendingTree's fha loan limit tool.
First Buyer Home Program Texas Mooney Adds Buyer Programs, Celebrates 70 Years – It first. Texas, plans to deliver 20 m20v acclaim ultra and M20U Ovation Ultra aircraft this year. Phillips said that number is expected to double in 2019. MooneyShares allows two buyers to share.
Apply For An FHA Loan – Federal Home Loan Centers – Apply For An FHA Loan When it comes to financing a new home, there are many financing options available to buyers. One of the more popular options is the FHA loan.
FHA.com Reviews. FHA.com is a one-stop resource for homebuyers who want to make the best decisions when it comes to their mortgage. With our detailed, mobile-friendly site, individuals can access information about different FHA products, the latest loan limits, and numerous other resources to make their homebuying experience easier.
Apply For An FHA Loan – Federal Home Loan Centers – What Is An FHA Loan? FHA, or the Federal Housing Administration, provides mortgage insurance on loans made by FHA approved lenders.This insures the lending institution against the loss of the loan's principal amount in cases where the borrower defaults on the loan or fails to meet the conditions or terms of the loan.
What is the downside of FHA 203K Mortgages? – 203K Loan 101 – Therefore, a very possible downside associated with the 203k FHA mortgage is finding out that the renovations required for your home is not on the list of acceptable renovation work. A downside associated with this type of loan as well is the interest rate. The interest rates on a FHA 203k mortgage loan are higher than other types of FHA loans.


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Ad Details
Ad ID: 2931
Added: February 14, 2020
Sale Price: 94,490
Condition: Brand New
Location: Jackson, MS, USA
Phone: 1-601-339-6265
Class: Class B
Year: 2020
Make: Dodge
Model: RAM PROMASTER 3500 H
Fuel: Gas
GVWR: 9350 lbs.
Mileage: 750 mi.
Views: 658
Website: http://van.life
United States
Contains optional:
Generator Onan 2.5Kw Propane $7,495 MSRP
Side and Rear Screen Door $2,545 MSRP
Build and price a custom-built unit with average of 90 day delivery at https://van.life/camping-models/
Design Highlights:
Built on Dodge Promaster Chassis
Large Bathroom/Shower
Lots of Storage Space
Tight Turning Radius for Daily Driving
2 identical units available. Vins 3C6URVJG5KE537224 3C6URVJG5KE537225
Custom build a Midwest van and request a quote at https://van.life/camping-models
We are a boutique new and used RV dealer in Jackson, MS specializing in class B vans. Owners Colleen and Brian have each driven Class B vans as daily drivers for almost a decade and know the ins and outs of these vehicles. We entered the business out of frustration with having paid the money these vans cost and then receiving poor service from dealers after the sale.
As we considered manufacturers to represent, we could not ignore the great experience we had as owners of Midwest Automotive Designs both with build quality and service after the sale. Midwest demonstrated to us that they will go the extra mile to ensure a great ownership experience for their customers.
All inventory is stored indoors and all batteries are constantly maintained while on our lot. We are a small company with low overhead and will not be undersold! Feel free to give us a call to ask questions about the vans themselves, our experiences driving them locally and across the country, or hear our personal testimony for Midwest and the over and beyond service they provided us.
If you are ready to buy, email us. You are deailing with the owners so there is no "good guy bad guy let me get with my sales manager" game. Make us a fair offer and you'll be a new owner!


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|Idkwhatmynameis (talk)
|Date Created:
|Please feel free to edit constructively!
Bonded Weapon [{{#arraymap: Fighter|, |x|Type::x}}] Summary::You choose a weapon, eventually growing stonger and stronger in it's use. Prerequisites: {{#arraymap: Base Attack Bonus +1|,|x|Prerequisite::x}}Benefit: This feat scales with your equivalent fighter level, levels in a class that do not provide fighter advancement instead provide 1/2 a level for full base attack bonus classes, and 1/4 of a level for 3/4 base attack bonus classes.
Bonuses by Level[edit | edit source]
|Fighter Level
|You gain a +1 to hit with the chosen weapon and you qualify as having the weapon focus feat for that weapon.
|You gain a +2 to damage rolls using the chosen weapon, and you qualify as having weapon specialization with that weapon.
|You gain the ability to, as a swift action, double your reach with the chosen weapon, taking a -2 penalty to the attack roll. You also gain the improved critical feat when using your weapon of choice.
|The ability to double your reach is now a free action, or it can be used as a swift action with no penalty.
|You gain one of the following benefits, based on the type of damage you weapon inflicts;if it is slashing, you gain the slashing flurry special ability, if it is piercing you gain the Vital Stab special ability, and if it is bludgeoning, you gain the Demoralizing Attack special ability. Lastly, you may now triple your reach as a free action, taking a -2 to attack, and you are considered prone for the rest of the round.
Slashing Flurry: When wielding a slashing weapon, you may make an extra attack at you highest base attack bonus, but that attack and all others during this turn take a -3 penalty. This would grant you 2 extra attacks for using 2 slashing weapons.
Vital Stab:As a standard action, which in addition to normal damage, deals 2d4 points of ability damage to Str, Con, or Dex.
Demoralizing Blow: For every succesful attack against an opponent, that opponent takes a -1 penalty to damage rolls, and a -1 to hit for every 2. This applies until they succesfully attack you again.
Special: This feat does not stack with weapon focus or weapon specialization.
Back to Main Page → 3.5e Homebrew → Character Options → Feats


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IDG-backed Chinese Rental Apartment CJIA Nabs USD 300 Million Fresh Funds
Property developers are looking forward to raising property income and increasing tenant engagement while long-term apartments operators are changing the market.
Chinese rental apartment operator CJIA Apartments Group (城家) has secured USD 300 million in Series A round of funding from Boyu Capital, a Hong Kong-based private equity firm, according to tech media 36Kr.
Alibaba-affiliated Yunfeng Capital, Huazhu Hotels Group, and CCB International were also involved in the transaction. CJIA, which operates 20,000 apartments across China, will be using the fresh cash to fuel urban properties, branding, channels expansion, and technology. The company has raised USD 50 million in Pre-Series A round of funding from Huazhu and IDG Capital.
It is a record-setting amount of funding in the long-term and centralized apartments market. March, Mofang raised USD 150 million in Series D; Danke, a decentralized brand announced USD 500 million funding meanwhile. Momentum concentrated on top players.
Founded in 2015, CJIA Apartments Group is a joint venture set by Huazhu and IDG. The JV enables Huazhu to make a foray into non-standard accommodation business. It now has over 100 apartments, targeting at tier 1 cities such as Beijing, Shanghai, Guangzhou, and Shenzhen.
CJIA operates various levels of accommodation. Its CJIA Apartment provides youngsters economic products that are priced at CNY 2,500 (USD 351) to CNY 5,000 (USD 702); Premium brand CJIA Aparthotel Prime costs between CNY 5,000 and CNY 8,000; Serviced apartments targeting at businessmen, such as CJIA CitiGo and Citadines, rent range from CNY 10,000 to CNY 15,000. It started to launch luxury apartments that cost more than CNY 20,000 for one month in Shanghai July.
CJIA's CEO and Huazhu's president Jin Hui claimed that the average occupancy rate of apartments for the company's mature-stage brands has surpassed 95% and every single apartment has started to bring positive margins. The company believed in clearer and growing needs of customers towards quality when choosing apartments. It then built branded and standardized services to suit the needs. Originated from a hotel brand, CJIA's can establish its product mix that includes long-term and short-term accommodations successfully. Huazhu brings 50% of customers to CJIA, according to the report.
The company added product portfolio further – by utilizing the flexible time of its long-term apartments and creating a new brand called Stay-live as you want. Occupiers can choose to live for several days to months. The company CEO Jin thinks the new niche market has huge growth potential, as still in its nascent stage. CJIA intended to capitalize on the theme and harvested good results till now – 20% of orders come from the business. Smart technology lets the company manage the division well. The company claimed to have the first proprietary CAS system to coordinate long-term and short-term occupancy.
For long-term apartment operators, value is created by the price premium and concierge-type services. In cooperation with several property management entities, the company has closed dozens of important heavy-asset programs in Beijing and Shanghai. Players like CJIA can offer REITs, governments, and property developers with operations experiences and financial channels as property developers are looking forward to raising property income and increasing tenant engagement.
There may be a long-term need to design and offer tenants with elevated service levels and amenities. But CJIA's top pursuit of safe, convenient, and clean accommodations fit the current stage of long-term apartments market in China enough.


text: Harry Potter and the Deathly Hallows: Part 1 We have found 1 items matching your search query. Sort By: TitleDatePrice List Grid Daniel Radcliffe jacket from Harry Potter and the Deathly Hallows Part 1 Join or Login to View Results (Warner Bros., 2010) Grey corduroy jacket worn by Daniel Radcliffe as "Harry Potter." Internal Angels Costumiers label with "Daniel Radcliffe January 09" written in ink. Angels Costumiers COA ... More Details 1 Page 1 of 1 Advertisement


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"Joanna Walsh is fast becoming one of our most important writers." Deborah Levy
Joanna Walsh is an internationally-published writer of fiction and creative nonfiction. She is also a critic (The Guardian, The New Statesman, Los Angeles Review of Books), and an editor at 3:AM Magazine and gorse editions. She was a judge on the 2016 Goldsmiths Prize and won the Arts Foundation Award for Creative Non-fiction in 2017. She founded @read_women.
She is the author of Vertigo, Hotel, Fractals, Grow A Pair, Worlds From The Word's End and the digital work Seed-story.com. Her 'novel in essays' Break.up was published in the UK by Tuskar Rock Press and in the US by Semiotext(e) in Spring 2018.
Picture here..


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Your Apple MD318LL/A is a powerful notebook computer with an innovative aluminum unibody design. With all-new quad-core and dual-core processors, the new MacBook Pro isn't just faster. It's phenomenal.
The 15.4-inch MacBook Pro features discrete AMD Radeon graphics for stunning visuals. New Thunderbolt technology lets you connect high-performance peripherals and high-resolution displays to a single port, and transfer files at lightning speeds. With FaceTime HD camera, your friends will see you three times more clearly than before. The spacious Multi-Touch trackpad lets you use gestures to control and interact with what's on your screen. Even with faster processors and more advanced features, the new MacBook Pro lasts an amazing 7 hours on a single charge. MacBook Pro has more than its share of innovations.
Warranty:90 Day Warranty
- Intel Core i7 2.2 GHz Quad-Core Processor
- 4GB 1333MHz DDR3 SDRAM
- 500GB 5400rpm Hard Drive
- 8x DVD/CD SuperDrive
- 15.4-Inch LED-backlit Display (1440-by-900 Resolution)
- AMD Radeon HD 6750M with 512MB GDDR5
- OS X Lion 10.7 or higher pre-installed
- Multi-Touch smooth glass trackpad
- FaceTime HD camera with widescreen HD video
Packaging:Non-Retail (Bulk Packaging)
What you get:One [1] Laptop
One [1] Charger


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How Does a USDA Construction-to-Permanent Loan Work. – · Once you can move into the home, your construction loan automatically turns into a permanent mortgage. At that point, the loan is re-amortized to reflect the remaining principal for the remaining term. You then make standard principal and interest payments as you would for a standard purchase loan.
PDF Construction-to-Permanent Financing: Single. – Fannie Mae – construction loan and the permanent financing at the same time. These types of loans are eligible for delivery to Fannie Mae when construction is completed and the loan converts to a permanent phase – subject to certain Selling Guide requirements that are summarized in this matrix. Construction Phase
M&T's Matt Petrula on His Appetite for Construction – Today, M&T doesn't shy away from sizable construction loans on some of the Big Apple's most interesting. We did a little bit of construction lending but for the most part it was permanent mortgages.
Affordable Buffalo Community Scores Construction Financing – KeyBank has financed elim townhomes in Buffalo, N.Y., with a $5.4 million construction loan and $6.7 million in 9 percent tax credit equity. additional financing was provided by the New York State.
TheTexasMortgagePros.com offers one and two time close construction loans – The construction-to-permanent loan is made directly to the borrower, a consumer-direct loan. They receive a monthly statement for the interest payment due for the given month. They have twelve (12) months to build and complete the construction from the date of closing and funding.
veterans affairs mortgage calculator los angeles mortgage rates buy a foreclosed home 580 credit score mortgage lenders VA Mortgage Calculator | U.S. Bank – This VA home loan calculator provides customized payment and rate information based on the information you provide. A VA mortgage loan does not require a down payment, but may include additional costs such as a funding fee. A funding fee is a mandatory one-time fee paid directly to the Department of Veterans Affairs (VA). The fee is a.
Construction Renovation Loans – umpquabank.com – Build your project under one roof. Construction and renovation loans have a few more moving parts than other home loans, but rest assured Umpqua has the experience to help turn your dreams into reality. For every project, you'll work with Umpqua and a dedicated construction team from start to finish with no outsourcing – no exceptions.
mortgage pre approval requirements Know This Before Getting Pre-approved for a Mortgage – MagnifyMoney – The best thing you can do to ensure a smooth mortgage application. A Crucial Step in Qualifying for a Mortgage Is Getting Preapproved.
VA Construction to Permanent Loan – flamortgagefirm.com – The VA construction-to-permanent loan allows home buyers to build a home with no down payment and with an all-in-one financing option for construction, buying land and the funding of a "permanent" mortgage with one closing.. This construction loan requires current military experience or prior with an honorable discharge.
how to pay off home mortgage faster How To Pay Off Your Mortgage Faster – American Dream Home. – A little more can be paid every month: Though refinancing is a good option, one can still get all the benefits of paying off a mortgage early without incurring a cost on refinancing and this can be achieved by paying a little more each month.
These may also be known as "all-in-one loans" or "construction-to-permanent loans." They wrap the construction loan and the mortgage on the completed home into a single loan. During the construction phase, you'll make interest-only payments on the funds that have been disbursed.
how much is a typical mortgage payment Mortgage Calculator – Work out your mortgage repayments and. – This is a guide to how much you'd pay each month. Adjust the sliders to change the term to the number of years you have left to pay, and increase the interest rate. The exact amount will depend on the type of mortgage and the lender.can you mortgage a foreclosed home The mortgage industry isn't ready for a foreclosure crisis created by climate change – In Hurricane Harvey's federally declared disaster areas, 80 percent of the homes had no flood insurance, because they weren't normally prone to flooding. Serious mortgage. "We literally can avoid.
Buying a new construction home can involve lots of exciting choices and unique opportunities. When you're ready to buy, compare home loan options and navigate the financing process with a Wells Fargo home mortgage consultant who specializes in financing for newly constructed homes.


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The (Longer) Long Tail – Chris Anderson
(Note: I read this book in 2007, and back then it didn't have "Longer" in the title. This is a repost of a review I did then in Visual Bookshelf on my Facebook.)
When this was written, back in 2006, I can imagine it being highly interesting. Today I don't think most people would raise an eyebrow as the concept is so common: digital distribution is so cheap you can have an almost infinite amount of products in your catalog. So many in fact that even if you only sell one copy of each one the total sales from these "long tale products" adds up to a considerable increase in revenue for the company. Still it's very interesting. He still has some valid points that most business hasn't quite handled that well: by having an almost infinite variety of products, how do the customers find what they want?
Conclusion: Read it, if you have some extra time. Definitely a must-read for anyone starting or running an online service with a very large product catalogue. (2011 update: Today his new book Free might be more interesting.)