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February 2017 Funded Microgrants
February 2017 Funded Microgrants
Mini-1 Intracellular Calcium Signaling in Patients with Severe Epilepsy
Epilepsy, characterized by periods of uncontrolled vigorous shaking, or seizures, affects approximately 1% of the population. Seizures can be very difficult to treat sometimes requiring several medications, while 30% of patients are unresponsive to treatment. Many cases of epilepsy are genetic in origin and a large number of causative genetic mutations have been identified. Recently there have been enormous advances in the development of new anti-seizure medications using the knowledge from genetics, and treating the condition of individual patients, thus developing and perfecting the notion of personalized medicine. For some novel genetic mutations associated with epilepsy, no disease mechanisms have yet been elucidated. These cases where we do not yet know how the genetic defect causes seizures are much more difficult to treat. One such mutation associated with epilepsy is in the RYR3 gene, which affects a specific calcium channel in the brain, but experimental evidence for how the mutation causes epilepsy is totally lacking. In other cases the genetic mutation puts patients at risk of dying unexpectedly, as in cases with mutations (SCN1A) in sodium channels. These mutated channels also alter calcium signaling in brain cells. We will perform experiments in cells derived from the patient's blood that behave like brain cells and carry the RYR3 or SCN1A mutation to identify abnormalities in brain cell signaling caused by the mutated channels. Control experiments will be done on close relatives not carrying the mutations in question. The goal of these experiments would be to translate the knowledge obtained, into treating individual patients with epilepsy with medications that alter the calcium or sodium levels in the brain. This would not only mean a better quality of life without seizures, but ultimately saving the lives of those patients who are at risk for sudden death in epilepsy.
19-16 Establishing patient-derived cell lines for testing new therapies for Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is an inherited disorder caused by mutation of the dystrophin gene. This causes a deficiency of the muscle protein, dystrophin, which is essential for muscle integrity and function. This disorder is carried on the X chromosome and primarily affects boys, who experience progressive weakness leading to difficulty walking, running and jumping and all boys are in a wheelchair by the end of their teenage years. It also leads to progressive respiratory insufficiency requiring support for breathing as well as affecting the heart muscle. The mean age of death is about 28 years. About 10% of DMD patients have a type of mutation that creates a stop signal within the dystrophin gene so the dystrophin protein is cut short at the mutation and cannot function. Ataluren (PTC 124) is a drug designed to enable cells to ignore the premature stop signal and produce full-length dystrophin protein, a process called premature termination codon (PTC) read-through. In clinical trials, some patients receiving Ataluren showed slower disease progression while others did not. It is important to understand why patients respond differently. We will make immortalized cells from the blood of two DMD patients with different mutations. These cells will be differentiated into muscle cells and treated with various PTC read-through drug candidates to determine how much dystrophin they produce and if it is possible to predict which patients may be more sensitive to the drug. A positive outcome could lead to tests to predict which patients might benefit from the treatment.
19-21 GOT2 deficiency: studying a rare inborn error of metabolism to understand brain metabolism and targets for epilepsy treatment
Epileptic encephalopathies encompass a group of debilitating and potentially life-threatening neurologic conditions. Accurate diagnosis of the underlying cause, especially inborn errors of metabolism, is essential as this allows for targeted treatment, which can prevent brain damage and improve daily functioning and outcomes for affected children. Our team applied genomic technologies to study a 5-year old boy with severe seizures, developmental delay, and unexplained biochemical abnormalities in blood and spinal fluid. Excitingly, the team identified a novel rare neurometabolic disease characterized by mutations in the gene GOT2; this discovery allowed for treatment with nutritional supplements targeting the metabolic defects. The patient's response is promising; seizures and head growth have improved although many serious challenges remain. Our goals are to understand the mechanisms underlying this rare neurologic condition which causes developmental delay and epilepsy, to enhance early identification and to develop better treatment strategies. We have already created cell lines missing GOT2 and now plan to study the chemical changes important to brain function. We aim to use the study results to develop more precise diagnostic and treatment methods for this rare epilepsy disorder. Central to our approach is an international collaboration between different disciplines, student training, family participation, as well as a translational focus from bed- to bench- to bedside.
19-34 Chromium content of Pediatric Parenteral Nutrition solutions in Canada: Are Pediatric patients on Parenteral Nutrition exposed to toxic amounts?
Intestinal Failure (IF) occurs when a person's gut cannot work well enough to absorb enough nutrients and fluids. In these cases, life-saving parenteral nutrition (PN) is given through their veins for months or years. Special bottles of certain nutrients are added together to make PN solutions. Unfortunately, these bottles have been proven to have too much chromium (Cr). Chromium is a trace element; the word "trace" meaning that we only need it in very small amounts. Chromium assists the hormone insulin, which helps the body use carbohydrate, fat and protein. While the body needs Cr to function properly, too much is unsafe. The nutrition solutions used in PN contain high amounts of Cr because of contamination. This level of contamination does not have to be measured or included on the label of the PN solutions. Patients on PN may therefore get enough or even too much Cr from the contamination of the PN fluids and may not need additional Cr in their PN. High levels of Cr in blood and tissue may have a negative impact on kidney function. We have observed that patients on PN have high amounts of Cr in their blood; up to 20 times higher than normal. Also, we have observed that patients on PN for long periods of time (over 6 weeks) have problems with their kidneys. It is possible that the excess Cr is linked to the kidney issues. The goal of this study therefore is to determine the amount of Cr in the PN solutions provided to patients with IF. We will collect 10 mL of sample from the discarded bags of PN from 45 IF patients in hospital and 45 patients on home PN. Then we will measure the amount of Cr in each sample and compare the measured amount to that which was ordered to determine the level of contamination. The information from this study will help us decide if we need to order Cr in the PN for our patients or whether the amount present from contamination is already enough or even in excess.
19-24 Treatment of Medically Refractory Epilepsy due to Focal Cortical Dysplasia with mTOR inhibitors
Focal cortical dysplasia (FCD) is a localized brain formation problem that often causes difficult to control seizures. Individuals with FCD can have a sudden worsening of seizures, requiring admission to ICU, and non-response to anti-seizure medications. This can cause a great burden for families and the healthcare system. Many require urgent epilepsy surgery, where the abnormal brain tissue is removed to improve seizures. However, additional treatments are needed in the interim. Research shows that the mTOR pathway, involved in cell growth and function, plays a role in FCD. Recently, mTOR inhibitors were proven to significantly reduce seizures with a good safety profile in patients with Tuberous sclerosis complex, who have multiple small FCDs. Therefore, mTOR inhibitors may be useful in treating seizures in patients with FCD and very difficult to control seizures, while they await epilepsy surgery. This is a pilot study of this treatment that will be conducted in one clinic.
19-7 Protein restoration therapy for children with inherited thrombophilia
Inherited thrombosis is a very rare genetic disease in which the liver does not make anticoagulant proteins, leading to a high risk of deep venous thrombosis and embolism (serious clots) in infants and young children. Patients require frequent and sometimes life-long treatment with blood thinners (anticoagulant drugs). These are difficult to dose correctly and carry the risk of inducing life-threatening bleeding. In this project we will determine the potential of new drugs that restore the body's own production of anticoagulant proteins to better treat this disease without the risk of bleeding.
19-1 The gut microbiota as a target to resolve chronic diarrhea in children with microvillus inclusion disease
Microvillus inclusion disease is a very rare and severe genetic bowel disorder that affects infants and young children. Patients suffer from severe unstoppable diarrhea which complicates disease management and severely impairs quality of life. There is no treatment to resolve the diarrhea. Recent studies suggest a relationship between the diarrhea and the composition of the bacteria in the gut. Here, we will determine in detail the changes in the composition of the bacteria in the gut of these patients. We will identify targets for intervention in the composition of the bacteria in the gut to resolve the chronic diarrhea, and in this way improve patient care and quality of life.
19-33 Can phosphorylation of the E1alpha Subunit of Pyruvate Dehydrogenase Complex Help Predict the Prognosis and Direct Treatment of Pyruvate Dehydrogenase Complex Deficiency?
Pyruvate Dehydrogenase Complex Deficiency (PDCD) is a very serious condition that often results in death in infancy. It sometimes can present in a milder form with survival beyond infancy with development of learning difficulties or as dystonia, a disorder of movement where children are unable to control their limbs, torso or head. Sporadically it has been noticed that some children with PDCD are responsive to a vitamin called thiamine or a special diet. To date it is not well understood why the condition is more severe in one child over another or why only some children are responsive to treatment. We have attained samples from a male patient (6 years old) with a mild form of PDCD who is very responsive to thiamine. His debilitating symptoms of dystonia have all but resolved on thiamine supplementation and he can now walk home from school. We will use the samples from this patient to understand why thiamine was so successful in this child. This would help explain why mutations in PDC have such a variable effect, which will help doctors predict 1) the severity of the condition and 2) what therapy (thiamine versus special diet) should be used in treating the disorder.
19-37 Understanding the pathophysiology of vitamin B6-dependent epilepsy due to PROSC deficiency
Some forms of epilepsy in children are resistant to common antiepileptic medicines but can be stopped by treatment with vitamin B6. This disease is called GOT2 deficiency. These are designated as vitamin B6-reponsive epilepsies and attributed to inborn errors of metabolism. Recently a new form of these diseases was discovered that causes neurologic impairment in affected infants along with epilepsy. Little is known about the disease biology, and filling these knowledge gaps is important to improve diagnosis and treatment. We will create a yeast model for GOT2 deficiency to study the changes in biochemistry caused by the disease. Our goal is to gain more insights into the disease mechanism, and to define targets for intervention.
19-18 Role of lipid metabolic errors in frontotemporal dementia pathology
Frontotemporal dementia (FTD) is a fatal neurodegenerative disease that results in a selective degradation of neurons in the brain. Mutations in the granulin (GRN) gene, which result in low levels of its product progranulin (PGRN), have been identified as a major cause of FTD. Unfortunately, the mechanisms underlying this disease remain poorly understood. Our lab uses the nematode C. elegans as a powerful genetic system. We have created nematodes with mutations in GRN to study the effects of the loss of PGRN and to better understand howt his loss is connected to FTD. Our results so far suggest that a loss of PGRN may result in problems with lipid metabolism. These metabolic problems ultimately lead to cellular dysfunction and death. We will perform a mass-spectrometry based assay to characterize lipid metabolism in our nematodes that carry the GRN mutation. If this project is successful, we propose to validate our findings in patients with FTD by characterizing lipid metabolism in their tissues and provide clear, new insights into the pathology of this devastating disease.
19-29 Patient-Specific Modeling of Juvenile Idiopathic Arthritis-Associated Uveitis via Induced Pluripotent Stem Cells
Uveitis is a rare, chronic eye inflammatory disease of unknown cause that affects 7% of Canadian children with juvenile idiopathic arthritis (JIA), or 1:10,000 children. Uveitis is often painless, but leads to blindness, cataract and glaucoma when is diagnosed late. Why children develop uveitis and JIA is still poorly understood. Moreover, uveitis is often resistant to treatment. Therefore, new strategies are urgently needed to investigate the mechanisms of uveitis and find effective treatments for each patient. We will develop patient-specific induced pluripotent stem cells from children with uveitis and juvenile idiopathic arthritis, and then differentiate them into affected tissues. These are the uvea (the eye layer that become inflamed in uveitis), joint linings, cartilage, bone and endothelial cells. This will allow us to study the mechanisms of uveitis and arthritis directly on the affected sites, tests new medications and find individualized treatment for each child affected by this rare disease.
19-31 Characterization of Pediatric Idiopathic Recurrent Pericarditis in Canada
Childhood idiopathic recurrent pericarditis (IRP) is a rare and often unrecognized chronic inflammatory disease of the lining of the heart. IRP has not been yet investigated systematically in Canada. We will ask Canadian pediatric specialists how many cases of IRP they diagnose in a year, and analyze the patients' characteristics, risk factors and treatment regimens. This study will increase our understanding of this rare pediatric disease and provide the much needed clinical care guidelines that will improve the diagnosis and outcome in children diagnosed with IRP in Canada.
19-9 Mucopolysaccharidosis IIIB: Improving enzyme replacement therapy utilizing protein transduction domains.
Mucopolysaccharidosis IIIB is a genetic disease characterized by the accumulation of un-degraded cellular products in the brain causing neural degeneration and a significantly shortened lifespan. This disease results from mutations in the α-N-acetylglucosaminidase (NAGLU) gene. Because of these mutations, the NAGLU enzyme is missing in patients. Treatment by injection of the missing enzyme is ineffective as the administered enzyme fails to reach the brain because it is unable to cross the blood-brain barrier. Protein transduction domains are relatively small positively charged peptides that can be fused to biological enzymes. These peptides are able to facilitate the delivery of enzymes across biological membranes, including the blood-brain barrier. The fusion of the missing enzyme (NAGLU) to the protein transduction domain, PTD4, has the potential to improve delivery of active NAGLU across of the blood-brain barrier and therefore improve enzyme replacement therapy for the treatment of MPS IIIB.
Results - We created the Naglu-PTD4 DNA construct and introduced it into the genome of Sf9 insect cells. These Sf9 insect cells acted like a 'biological factories' by producing quantities of active Naglu-PTD4 enzyme that could be used for further testing. Naglu-PTD4 was purified from the Sf9 insect cells using fast liquid column chromatography with a yield of 11%. Preliminary uptake studies with Naglu-PTD4 and MPS IIIB fibroblasts showed a detectable increase in active Naglu within the cell (activity of Naglu in control fibroblasts was ≤ 0.3 U/mg and activity of Naglu in fibroblasts treated with Naglu-PTD4 was ≈ 5.3 U/mg). This preliminary data suggests that active Naglu-PTD4 was able to successfully cross fibroblast cell membranes. Successful uptake studies with Naglu-PTD4 on MPS IIIB fibroblasts are the first step in testing the delivery capability of PTD4. In future, we plan to conduct blood-brain barrier penetration studies on mice to test the ability of PTD4 to deliver the missing enzyme Naglu across the blood-brain barrier.
19-13 Locus heterogeneity in Niemann-Pick disease type C
Niemann-Pick disease type C (NPC) is a genetic condition that affects the body's ability to transport and handle cholesterol. In patients with NPC, the cholesterol accumulates in a variety of tissues and causes signs and symptoms that can develop at any age and generally worsen over time. It can cause neurological problems, including difficulty coordinating movements (including of the eyes), speech problems, swallowing problems, stiffness, and dementia. Other problems can include severe liver and lung disease. Two genes are known to cause the disease, NPC1 and NPC2. It is important to diagnose NPC early since there is a treatment available to slow the progress of the disease. Our clinic follows a patient who has a very large spleen and laboratory findings that are typical for NPC, but who does not have any of the neurologic problems. His genetic testing for changes in NPC1 or NPC2 was negative, suggesting he may have a novel condition that mimics NPC. In order to provide our patient and his family with a genetic diagnosis, we will aim to identify the causative gene and gain some understanding of its function. Finding this gene may help the 10% of patients and families with NPC who do not have a mutation in NPC1 or NPC2. It may also provide insights into the cause of the neurologic problems we see in this condition.
19-38 Genetic basis of pyridoxine-dependent neonatal epilepsy in a consanguineous family
Some forms of epilepsy in children are resistant to common antiepileptic medicines but can be stopped by treatment with vitamin B6. They are designated as vitamin B6-dependent epilepsies and are attributed to inborn errors of metabolism. This study of families afflicted with these forms of treatable neonatal epilepsy will help to identify their genetic causes and improve diagnosis and treatment. Our team, specialized in research of this type of diseases, identified a consanguineous family who has a child affected which such a rare form of epilepsy. Seizures started in this child in day 3 of life and were controlled only by vitamin B6. Testing of a gene that is known to cause one form of this epilepsy was negative. We will perform more comprehensive testing (known as whole-exome sequencing) which will test all genes of this child in one experiment. This will help to identify the causative disease gene and subsequently improve diagnosis and help to devise therapeutic interventions.
19-6 Surgical Outcomes Of Rare Types of Strabismus: Development of a Canadian Registry
Strabismus is an eye condition where the eyes are not straight. Strabismus can lead to loss of vision in children or severe functional difficulties in adults by causing double vision. Rare causes include abnormal nerve supply to the eye muscles from genetic or acquired diseases. The resulting paralyzed or stiff muscle cannot move in sync with other muscles. Surgery to align the eye muscles are often not successful in such patients, and many different techniques are practiced. Because of the rare nature of these types of strabismus, each hospital may only see a handful of cases per year. Therefore, we do not know which procedures work best. Our goal is to set up a national database to collect information from multiple hospitals and eye care centres on these rare forms of strabismus. A collaborative effort across health care institutions will allow us to pool information and examine how effective different procedures are. An online database can be used to provide long overdue evaluation of surgical techniques used in rare strabismus. We will be able to statistically analyse the best surgical procedure by having enough numbers of these difficult cases which should ultimately result in stronger patient-centred care.
19-2 Cardiovascular Outcomes of Pregnancy in Turner Syndrome: A Multi-Center Retrospective Case-Control Study
Turner Syndrome is a genetic condition affecting 1/2000 live born girls where there is partial or complete loss of one of the X sex chromosomes . As a result, these women are mostly infertile, however, with newer technology they are able to achieve pregnancy through egg donation. The risk of pregnancy is thought to be high with 2% death rate quoted from research in small numbers of patients. Up to 50% of women with Turner Syndrome have heart abnormalities. The presence of these abnormalities has been shown to increase the risk of pregnancy. More research is needed to better understand the risk of pregnancy in this group. We have organized a network of researchers who look after these women to collect pregnancy outcomes data so that a clearer picture of risk can be presented to patients. We have identified approximately 155 women who have had a pregnancy at one of these sites, and this will be the largest group studied to date.
Results - Turner Syndrome affects 0.5% of women, and although many women with Turner Syndrome are keen to become pregnant, difficulties and risk surrounding pregnancy exist. With advances in reproductive therapies, more women with Turner Syndrome are able to become pregnant. This study aims to better understand the cardiovascular outcomes of pregnancy in Turner Syndrome. To date, 32 pregnancies have been included in the study. We plan to include up to 100 pregnancies and compare them to non-pregnant women with Turner Syndrome. The results of this study will improve our understanding of the cardiovascular changes that may occur during pregnancy, and the researchers are grateful to the Rare Disease Foundation for supporting this study.
19-14 Characterization of a novel mitochondrial disorder resulting in metabolic crisisWe have been caring for two young cousins who have both presented throughout childhood with episodes of devastating illness requiring repeated admission to the paediatric intensive care unit for resuscitation and emergency management. Each episode has been precipitated by a mild infection or slight dehydration. In between episodes the children are completely well and attend full time education with no difficulties. Recent studies by our team have identified the specific genetic change responsible for this illness in the boys. The change (one copy inherited from each of the children's parents) alters a gene that makes a protein that we know is important in the energy producing bundles in the cells called the mitochondria. We plan to 1. Identify other children that are similarly affected due to changes in this gene; 2. Undertake analysis to look at the different types of tissue (e.g. muscle, brain,) where this gene works and 3. Use yeast models to study the function of this gene in more detail. These complimentary studies will help us to understand why this gene change leads to this devastating, and likely under-recognized, condition and to develop strategies to avoid future episodes of crisis in the boys and other affected families. The work will also allow appropriate counseling of family members who are considering having children about the risks of having an affected child and establish the first steps in developing an effective treatment.
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As the youth champion for SGD 9 (Industry, Innovation, and Infrastructure), Jessica spoke alongside sixteen other exceptional young leaders all over the Philippines. During her speech entitled "From Ground Zero To Hero," she shared about her life-changing experiences in Marawi where she trained residents of the city right after the infamous siege.
As wrapped up her bit, she left a very eye-opening and hopeful message, "With the rise of online workers and digital advocates in Marawi, demand for better technology, infrastructure, and internet speed will follow, and will pave the way for a new type of employment in Marawi."
An empowered woman and Mindanawon, Jessica is one of the nation's pioneers in digital marketing and the online work industry. She was acknowledged for her role in advocating digital literacy and responsible use of social media through training and empowerment which she believes are catalysts in providing long-lasting solutions in today's global economic and technological problems.
Jessica's involvement in developing the Philippines' online work landscape has been very significant. She played a vital role in developing onlinejobs.ph, which provided a job platform for Filipinos to be connected with employers all over the globe.
Despite her hectic schedule, she imparted her knowledge about working online in various sectors in the country. She was part of the training team for the Department of Information and Communication Technology's Digital Jobs program. During which, she provided help and online work training to various rural areas in Mindanao, including the city of Marawi.
Local farmers and entrepreneurs were also given assistance by Jessica as a part of the Philippine Rural Development Projects Mindanao organized by the Department of Agriculture. She also played an integral role in the advancement of micro-, small-, and medium-sized enterprises through the Rural Impact Sourcing Training by the Department of Trade and Industry.
As an entrepreneur, Jessica founded and co-owns a digital marketing company, Coffeebot Solutions, which helps local and international businesses flourish on the internet landscape through effective use of online tools and social media. The company specializes in web design and development, search engine optimization, social media marketing, and management, email outreach, lead acquisition, paid campaigns, and video and graphic design.
Established as a small home-based company, Coffeebot had grown into one of Davao's leading digital marketing agencies providing exceptional online services to its clients. Located in Amalgated Building, Iñigo St., Davao City, the company has over 30 employees specializing in a wide array of technical and online expertise to serve small-and medium-scale entrepreneurs achieve success in their businesses.

subset: commoncrawl


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It was a table-flip of a weekend in the rugby world – the Boks came out on top over the All Blacks while Argentina trumped the Wallabies, but looking at the best try of the bunch scored, we have to give that nod to Israel Folau.
The Wallaby fullback (who had been shifted to the wing for the match in the Gold Coast) scored an breathtaking try from 50 metres out, taking a flat ball from Kurtley Beale and sidestepping the first defender, then beating a whole bunch more on the way to the tryline.
Check it out above.


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Hey Showmethesnow, Thank you for your analysis that you post on the forum. enjoy reading it; I don't post much but next winter, provided i"m still alive will purchase the weather model special in the fall and and try to keep up with everyone. Have a good week!
Jeff from Manassas
March Mid/Long Range Discussion 2
Vasnowboy replied to Cobalt's topic in Mid AtlanticTo PSU, CAPE, Bob Chill and those that make this wx forum come to life thank you! I read the remarks and learn a bit more. I'm a lifelong DC resident about to hit 50 yrs of age and think my first wx memory was Hurricane Agnes. I'm a snow lover first and foremost ever since I was 7 or 8. PSU thanks for keeping this winter wx hope on life support. Each winter seems to have a personality of it's own, this winter is sure strange....the discussions explain why it's so hard for snow to fall here this year. A 4" snow really would be wild if it occurred this March. Will end as I started and say thanks and will keep the faith


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University District Retailers are Ready. Are You?
University of Calgary Properties Group cares about the health & well-being of our community. Our Discovery Centre has resumed normal operations. To ensure everyone's health & safety some new procedures will be in place. We look forward to seeing you! Read More
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Celebrate Sandwiches and All Their Makings Scores of up-and-coming restaurants are surfacing in University District. We have news about…


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A scenic summer panorama view of the Colorado front range Rocky Mountains Continental Divide above Denver and Boulder. This is a part of very large 30 image panorama divided into five parts. Put all five together for a very large panorama fine art if printed on canvas could be over 40 feet wide.
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Michael has served in the eCommerce industry for 8 years, bringing his expertise to Classy Llama as a Solutions Architect. During his time working directly for a merchant, Michael was able to build online sales from ~$100k to nearly ~$3M, through replatforming and digital marketing.
Things I Love:
My wife, God, people, incredible flavors
Things I Hate:
When people use the word "literally" figuratively.
Favorite Places:
Anywhere my wife is. New York City. London. With my family in the Netherlands. A mountaintop in the middle of the woods, surrounded by nature. The beach.
Favorite Quotes:
It ain't what you don't know that gets you into trouble. It's what you know for sure that just ain't so. – Mark Twain
When I stand before God at the end of my life, I would hope that I would not have a single bit of talent left, and could say, 'I used everything you gave me'. – Erma Bombeck


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Where: Mr Tipply's, 347 Kent St, Sydney. Vibe? 1940's night club. Taste: Delicious. Written by Steph Nash and Sabrina Muysken.
Anthony Minghella's 1999 film, The Talented Mr Ripley (1999), is a twisted story of love, lies, obsession and murder. The best part? The jaw-dropping beauty of the star-studded cast, featuring the baby-faces of Matt Damon, Jude Law and Gwyneth Paltrow.
Much like the film, Kent Street's Mr Tipply's is a beautiful mystery. Is it a bar? Is it a pub? Is it a restaurant?
Well, as the Spanish would say: porque no los dos?!
Walking in to the newly-renovated upstairs restaurant and bar is like walking in to a sultry nightclub from the 1940's. The atmosphere is elegant, chic and soothing, with lighting more practical than most Sydney bars. A pianist welcomed us in with a tribute to Elton John, giving the vintage vibe a humble modern touch.
The seating arrangements are classically demure, as we take to a corner booth and find crystal glassware atop a mirrored table. Amongst the music and decor, one can't help but feel fervently glamorous. If you're looking to take a loved one on an intimate date, this is definitely a swoonable option.
What is most interesting about Mr. Tipply's is the array of choices and prices on the menu. It is vastly unusual for a menu so gourmet, settled in an atmosphere so elegant, placed in a location so attractive, to be so affordable. For a standard cocktail at a surrounding venue, you're probably looking at an average price of $20. At Mr Tipply's, the average price is an acceptable $15, so you won't have to skimp on the booze to be able to afford a main meal.
For the mains, the average meal price is around $25 – which is suprisingly cheap considering the location. Describing the cuisine at Mr Tipply's is a relatively hard task. Hearty, and yet affordable, one is tempted to pass off the venue as a pub. But with such mouth-watering gourmet dishes as seared scallops, Atlantic salmon, and snapper fillet, you couldn't do the chefs the injustice. At best, it is modern-Australian combined with Asian-fusion, and affordable enough to warrant the foodie term "gastro-pub".
Despite Sydney's latest health trend, being a vegetarian still poses a culinary challenge. Unless you're dining at an exclusively vegetarian or vegan restaurant (um, yum!) you'll be hard-pressed to find more than one edible dish on offer. Vegetarians of Sydney rejoice! Mr. Tipply's dinner menu has not one, but three main course options.
To awaken our taste buds, we ordered the Edamame as a starter. With a salted casing protecting the warm beans inside, this healthy favourite didn't disappoint.
For mains, we were lucky enough to sample a variety of items on the menu, starting first with the Snapper Fillet. The snapper was cooked to perfection – crispy and salty on the outside, lush and tender on the inside. The fish fibres were melt-in-your-mouth satisfying, and were coupled divinely with a spicy bed of chickpeas and gremolata. The gremolata was rich and tomatoey, with just the right amount of spice.
On the vegetarian side of things, we had the Spiced Pumpkin & Beetroot Salad along with the Vegetarian Halloumi Cheese Burger – how gluttonous! As self-proclaimed spice enthusiasts, a salad of such description should prove to be a salivating success. Unfortunately, the name was somewhat misleading. Albeit the pumpkin was cooked to near perfection and nicely complimented by beetroot, lentils, onion and a sunflower seed mix – but spicy it was not. With light and fruity raspberry vinaigrette the meal held a mild flavour, but lacked that extra-spicy kick to really wow the taste buds.
With a refreshing burst of cucumber and capsicum to neatly counteract the Halloumi zest, the Vegetarian Halloumi Cheese Burger ticks all the vegetarian boxes. Leaving you satisfyingly full yet not overcome with that sickly feeling burgers all too often leave in their wake, this is one for your must-try list. And to wash it all down? A delectable non-alcoholic mocktail full of lychee, mint, lime and a hint of blueberry – the perfect dinner companion.
Skipping suddenly to the more carnivorous side of the menu, we had Mr Tipply's pièce de résistance – the 500gm T-Bone Steak. Those of you lusting after the perfect steak need not look any further. When slicing through the steak, the knife slid straight through the tender meat. Lightly pink on the inside and deliciously charred on the outside, the most expenisve item on the menu is definitely worth its price tag. If you were to order the same thing from Neil Perry's Rockpool Bar and Grill, it would easily cost you an arm and a leg (roughly, an extra $15).
Lastly, we had the Mongolian Lamb Cutlets with Steamed Greens. Perhaps we should've eaten these first… After the T-Bone, there was just no comparison. We had unfortunately peaked too early. The cutlets were missing that succulent juiciness that the steak had pleasantly provided. The steamed green vegetables were fragrant and delicious – but as a whole, the dish could not compare to its more successful sibling. We finished the night with a delightfully refreshing Pimms No 1, which was colourfully decorated with strawberries, organges, cucumber and mint.
So, what did we conclude from the glamorously mysterious Mr Tipply's? We decided that gastropubs were no longer a thing of the future – the time is now people! If you want hearty pub food on a modest budget, you've got it. If it's elegance and romance that you want – hey, why not have that too. It's the best of both worlds: relaxed, delicious and good on any occasion.
Cheers to Mr Tipply's – thank you for showing us the future of the gastropub. See the Mr Tipply's website for more details.


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There are many common causes of car accidents that get a lot of attention: drunk driving, texting while driving and inattentive driving, just to name a few. But one of the most common and deadly causes of car accidents is a hazard that all drivers tend to take for granted: speeding.
According to the Insurance Institute for Highway Safety, about 27 percent of car accident deaths in 2015 involved speeding. Driving too fast for conditions makes a collision both more likely to occur and more likely to be fatal.
Despite the risks, speeding is a major temptation for most drivers. Therefore, at least one automaker is addressing the problem by placing limits on just how fast we can go. Earlier this month, Swedish car company Volvo announced that it will soon be reducing top speeds on all its new vehicles to no more than 112 mph.
To be sure, the vast majority of crashes occur as speeds well below 112 mph. Moreover, Volvo isn't really known as a thrill-seeker's automaker. Nonetheless, the company's move may be the start of a larger conversation "about whether car makers have the right or maybe even an obligation to install technology in cars that changes their driver's behavior," according to Volvo's CEO. Cars are increasingly adding safety features meant to compensate for human error or protect us from our own bad choices. Volvo's decision to limit speeds seems to be an extension of that.
For the time being, each of us is responsible and liable for the way we drive, including the decision to speed. If you or a loved one has been seriously injured by a negligent, speeding driver, you have the right to seek appropriate compensation with the help of an experienced personal injury attorney.


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Why Planes Dump Fuel Before Landing – Picture this, you're nestled cozily in your window seat on a jet airliner when suddenly, you notice weird white spray coming out the back of the wing. Is something wrong with the plane? Are you going to crash? No need to panic! At this moment, the pilots are performing a standard procedure called fuel dumping.
But the reason why they get rid of fuel, which is by no means cheap, is another story. So, it's not totally uncommon for airliners to dump fuel while flying; what's more, pilots do it intentionally. At first, it may sound like a huge waste. See for yourself: a mid-sized Boeing 737-300, designed for short and medium-range flights,uses about two and a half tons of fuel per hour of travel.
The price of jet fuel is more than $600 per ton, so that means that while flying such a plane, you spend approximately $1,500 per flight hour. In other words, when a jet travels from New York to Los Angeles, which takes four and a half hours, it burns nearly $7,000 worth of fuel. I would say that's impressive. So, let's figure out why pilots literally throw away a fortune!
The truth is that in certain situations, fuel dumping turns out to be cheaper than the alternative! Most planes must be lighter when they land than when they take off, like more than 200,000 pounds lighter! The problem with landing is that it puts much more stress on a plane than take-off, that's why the less weight a jetliner carries, the better. If a plane doesn't use a certain amount of fuel before landing, it might hit the ground too hard, which can lead to some serious damage.
On the other hand, pilots don't usually have to worry about too much fuel in the tanks because the problem takes care of itself. During a flight, a commercial plane burns almost all the fuel, and by the time it arrives at the destination, it's light enough, and ready for a safe landing. But from time to time, emergencies occur, and planes are forced to land way earlier than planned.
That's when fuel dumping comes into play, and it usually happens right before landing. Let's say that after take-off, Captain Kirk discovers that there's an urgent maintenance problem, or a passenger has a medical emergency. Surely, pilots can burn fuel by flying around with the flaps or landing gear dropped. But obviously, this maneuver won't save the day in case of a medical emergency when time is of the utmost importance.
That's when it's time to eject fuel. Few people know that most fuel is stored in the wings of an aircraft. That's why, when a pilot flips a switch in the cockpit, a sophisticated system of pumps and valves comes into action, and special nozzles in the wings let out excess fuel. This amazing system can get rid of thousands of pounds of fuel a minute, and that's exactly what you're seeing from your window seat.
On the other hand, not all planes have this complicated system. For example, narrow-bodied planes like the Boeing 757 or Airbus A320 can't dump fuel. This ability is more typical for more massive metal birds that have additional fuel tanks. But then, what alternatives do smaller planes have? Well, for them, the only way out is to land overweight.
Unfortunately, in this case, damage to the plane can be severe, and the repair – way costlier than it could be should the aircraft dump fuel. Besides, under such circumstances, a plane might be simply unable to stop in time. And if worst comes to the worst, an overweight landing might lead to a fire and result in a fuel explosion.
That's why, if the plane's construction allows it, pilots prefer to eject fuel rather than to risk people's lives. In fact, fuel dumping isn't a common procedure that happens regularly. That's why air traffic controllers often help pilots in the process and keep them away from other planes. Ok, this is all well and good, but seriously, should I open my umbrella if a plane flies over in case it starts raining gasoline?
You can relax; there's nothing to worry about. Most fuel evaporates while still in the air and never hits the ground. However, it's more likely to happen on a warm day, or when a plane ejects fuel high up in the sky – ideally, more than 5,000 feet. It may seem terrible from an environmental pollution standpoint. But here's one bitter truth: one way or another, when planes fly up there, all the fuel ends up in the atmosphere anyway.
By the way, every plane must carry more fuel than is necessary just to cover the distance from point A to point B. Before the departure, Captain Kirk has to make sure that the plane has enough fuel for all kinds of emergency situations. Therefore, there must be – trip fuel, which a plane needs to take off, climb to the cruising altitude, cruise, descend, and touch down
– Fuel needed if a plane will have to land at another airport;
– Reserve fuel;
– Fuel that can be used in unforeseen situations, for example, strong headwind or arrival delays;
– Taxi fuel, which a plane burns on the ground;
– And additional fuel for all kinds of emergencies, such as an engine failure.
Wow, that's a lot. No wonder a plane has to get rid of this load before having a smooth landing! Here's a story for you. On December 29, 2014, Virgin Atlantic Flight VS43, bound for Las Vegas, took off from Gatwick Airport. Shortly after, the pilots realized that the plane's right-wing landing gear had gotten stuck and hadn't retracted.
The only way out was to turn back and land at Gatwick. But the plane was a Boeing 747, also called a "jumbo jet" – a huge, four-engine machine. The fuel-laden aircraft was prepared for a long transatlantic flight and was way too heavy to land safely so shortly after the departure. And don't forget about the malfunctioning set of wheels!
At first, the pilots brought the plane to an altitude of 10,000 feet to drop it sharply to dislodge the trapped gear. When that didn't work, the plane started circling at a low altitude, burning fuel. The trick is that the closer to the ground, the more fuel a plane burns. Up high, at cruising altitude, the air is way thinner, and its resistance is weaker;that's why aircraft don't need as much fuel to keep moving.
Anyway, after circling for several hours, the pilots finally ejected enough kerosene over the territory of southern England to return to Gatwick. Luckily, even with the failed gear, they managed to land the plane smoothly, and more than 450 passengers and crew members were safe, with nothing more than minor injuries.
By the way, if you're still wondering why on Earth fuel is kept in the wings, here's the answer!First, it helps to reduce the stress airplane wings experience during take-off and climb- after all, they have to lift hundreds of tons up in the air. It puts so much stress on aircraft wing roots that they can literally bend upward! So, to reduce this stress, the wings get loaded with fuel, which makes them more rigid and heavier, and reduces the bending.
For example, the Airbus A380-800, the largest passenger plane nowadays, doesn't have the center tank at all. Instead, each of its wings can hold more than 264,000 pounds of jet fuel. Anyway, one more reason for locating fuel tanks in the wings is to lighten the aircraft's fuselage, which reduces the pressure on the wing roots as well.
On top of that, wing fuel tanks keep the center of gravity of the plane in the desired position. If all the fuel was stored in the nose or tail of the aircraft, the center of gravity would change along with the fuel consumption, and it would mess with the plane's stability. So there.
Have you ever seen a plane dumping fuel? Let me know down in the comments.


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Marine Metallic Stripe
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Delphinium Inca Fringe
Oyster Shell Coloured Lace 15mm
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Yuma Funding
Listing Details
Consumer Lending
Tammy Sherman
1780 S 1st Ave, Yuma, AZ, 85364
Under 500k
1 to 4
Yuma Funding 1 to 4 employees, with average earnings less than $500,000 per year. Yuma Funding company in Yuma, Arizona, categorized under Consumer Lending.
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text: Regardless of your experience level, developing an effective SEO strategy is something that must be accomplished in order to understand the needs of your company and meet and exceed those needs. It can be difficult to know where to start or even how to begin this daunting process. However, utilizing the SWOT technique can easily simplify the process and put you in the driver's seat when it comes to creating an effective SEO strategy. An essential part of this process is learning how to identify and recognize your businesses strengths, weaknesses, opportunities, and threats. Once you can identify these four areas of focus for your business you can effectively carve out a path for your SEO strategy in order to maximize your efforts.


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UMF 12+ 400g
Taste: Sweet yet (savoury), creamy yet dry with delicious Manuka characteristics. Well balanced and moderately tangy with a clean, pure finish.
Usage: Tahi Manuka Honey UMF 12+ is ideal for everyday eating – by the spoonful, as a spread, or to add sweetness and flavour to smoothies and juices. Note: Heating Manuka honey can affect its unique properties.
The UMF® trademark (Unique Manuka Factor) is your guarantee that our honey is authentic New Zealand Manuka honey, containing all of the unique and natural properties that make Manuka honey so sought after around the world. All of our honeys are free from GMOs and GE, with no added sugar, water or chemicals.


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Less than a year ago, Central Marin police intercepted a planned excursion by a group of teenagers that could have ended in tragedy.
A teen-rented party bus, carrying 30 containers of hard alcohol, marijuana and prescription drugs, was prevented from taking its planned six-hour tour with the under-aged crowd. Recently, the driver of the bus, who was arrested for possession of his own drug paraphernalia and a switchblade, pleaded guilty to misdemeanor charges.
The "closure" of this incident is a strong reminder that our community must remain vigilant in educating our teens about the dangers of alcohol and substance abuse. Parents must take a strong stance to protect their teens from making irresponsible decisions that could end tragically.
While I know that many people may think that "teens will be teens," I hate to think what could have happened if those "silly" teens had continued on their party bus journey.
Parents must establish an open dialogue with their kids about the dangers and consequences of alcohol and drugs. They should know their child's friends and their child's whereabouts. Invading your child's privacy is your job and your duty — whether it's in cyberspace or the real world, you could be the key to preventing a dangerous false move or tragedy.
This time of year in particular, as prom and graduation season approaches, kids are more likely to want to "go big" with party buses and hosting social engagements in celebration of these milestones. I urge parents to get involved with the planning of these events and require responsible chaperones to be present.
Inform your teens that the party bus rental comes with a responsible adult on board; a party is allowable, but only with attentive adults present.
Establish clear rules and boundaries for your teen when they are with friends. Establish a level of trust and be clear that if your child violates that trust, there will be consequences.
You may be thinking that your teen does not use alcohol or drugs and does not associate with kids who do. As a parent who learned the hard way, I need to tell you, "think again."
The latest "California Healthy Kids Survey" of Marin County high school students shows that 40 percent of 11th-grade students report having consumed at least one drink in the last 30-day period, while 24 percent reported binge drinking; 30 percent have used marijuana.
This kind of behavior leads to other potentially tragic consequences including drunken driving, not to mention the long-term consequences of starting these habits early in life.
It is important to note that parents are not supposed to be "friends" with their children. The role of the parent is to protect, nurture and guide our children down a successful path in life. When we blur the lines, we send a mixed message.
Be a model for your child — be their rock, be their foresight.
No one ever said parenting would be easy, and we are fortunate to have strong resources in our community to offer support to parents in this journey.
There are actions parents can take and organizations that can help.
Common Sense Media (commonsensemedia.org) offers tools for parents. Locally, betheinfluencesf.com and beingadept.org focus on discouraging teen substance abuse.
The Marin Prevention Network involves six community coalitions collaborating to promote healthy choices and reduce risk. Parents should also be aware of local social host ordinances, laws that cite adults when minors consume alcohol and drugs at their home, with or without their parents' knowledge.
Being a parent is challenging, but it offers many rewards. Be the voice that guides your child to a successful future: that will be the reward of a lifetime.
Mary Jane Burke is the Marin County superintendent of schools, the parent of two children raised in Marin, and a grandmother.


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Royal Albert Hall
The Hall is a Grade I Listed building; and has been in continuous use since it was opened in March 1871. It was always conceived as a multipurpose building to host not only concerts of music but exhibitions, public meetings, scientific conversations and award ceremonies. It is a registered charity held in trust for the nation but is financially self sufficient: it receives no funding from central or local government.
Kensington Gore, London SW7 2AP
United Kingdom of G.Britain and N.Ireland - Europe


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I'm home! After 5 days of traveling + hanging out in Eugene with the Brooks Running crew for the US Olympic Track & Field Trials I'm happy to be home with my little people once again.
Friday after a 2am wake up call I finally made it to Portland around 1ish to make the drive with the other Brooks Run Happy Ambassadors to Eugene.
I was the only one new to the bunch so I was secretly stressed that I wasn't going to mix with them but I immediately felt like I was one of the bunch. All of them were lovely. I see why they all love getting together for this yearly Brooks trip.
I roomed with Emily! I was VERY excited to meet her because I've been reading her blog since before she had little people.
We stayed at a frat house that Brooks had rented that literally had views of the stadium steps away. I made some jokes about not ever thinking that my first time sleeping in a frat house was going to be when I was 34 years old with 3 kids. Dream big people, dream big. I kid. It was fun though and did bring me back to my college days where you had zero space and not a lot of privacy. It also reminded me how much fun I had getting ready for a night out with all my girlfriends and attempting to carry on conversations over the noise of blow dryers. I feel like a baby yet it's been 13 years since I was in college – sigh. Time moves too dang fast in some respects and not fast enough in others.
Brooks left no detail to chance. I am obsessed with the pillow cases they had for us as well as the new Victory Collection Launch they gave each of us. I won't be running in them because I want them to last 34092348 years.
Who wouldn't want to drink out of these Brooks glasses?
After dropping off our bags quickly we headed right to the track to spectate the afternoon events.
Yes that is a runner laying down on the track mid-race. Needless to say, some races were more dramatic than others!
Once the races were over we headed to the Excelsior Inn for dinner and wine. After oh around 25 hours straight of being up, I was more than ready for bed. Emily warned me that the sun rose early in Eugene and she wasn't kidding.
After a month that included a trip to the beach with my little family I'm fairly certain that the amount of glasses of wine I've had rivals the amount of miles I've run. So yeah I don't feel prepared AT ALL for my half marathon coming up in San Diego in less than two weeks {Coupon Code: IRUNTHISBODY gets you a discount on all the races in the series}. Instead of racing it, it's going to be a nice long fun run. It's a good thing I like running long for fun, so it's all good.
I'm signed up for a couple of Rock N Roll races coming up and if I can make them work then I'm going to pick one of those as a target half. More on other running plans later as well as how I plan to get back on track before leaving for San Diego……
AND before I forget I really want to thank Brooks for the entire weekend. I'm certain I won't ever forget that time I got to go watch some of the fastest people in the US duke it out for a chance to go to Rio. The whole weekend still doesn't even seem real. Thank you!!


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Postgraduate Courses
Full time students are expected to choose 2-3 modules per semester from the list provided above. Each module has one class meeting per week for 2 hours. Those students who opt for five papers instead of a research paper will have to choose three modules. If a student is going to do a research paper he/she will have to start working on the research from the first semester.
African Sociolinguistics and Globalisation
This course provides an introduction to the history of the English language and the relationship of English to African Languages. Furthermore, the course explores the context and effects of English as a global or international language. There is also a specific emphasis on the use of English in Africa and how it interacts with African languages. The implications of this use of English in a postcolonial Africa, and the effect it has had on the peoples of the continent are explored. Essentially, we are looking at the history of English as an international language, its spread and impact on African languages, and the consequences of this spread for individuals and societies.
Translation and Interpreting Studies
The course is intended to:
- develop a general understanding of the subject of translation and its relationship to language planning (corpus planning);
- to provide an understanding of the translation theory;
- help explore how translation can be used in African languages to facilitate their intellectualisation;
- distinguish between technical and literary translation;
- explore strategies that one can employ in the translation process;
- consider some challenges and/or problems that translators, especially in African languages, are often confronted with;
- assist in understanding the process and the stages of translation; and
give participants skills to use the knowledge and skills given above in practical translation by undertaking translations of selected 'technical' and 'literary' texts.
Language Planning and Policy
This course examines the principles from which South African Language Policy has been derived. This will be carried out by looking at the historical background of South African Languages and also comparing it with language planning of other countries. The course will look at how the government, individuals, organisations and groups have influenced the language use and development in a multilingual country like South Africa. There will be an emphasis on factors underpinning language planning decisions at local, national and international level. Students will be encouraged to employ the knowledge gained in their own languages. The course's aim is also to illustrate relationship/link in all the other modules on offer for example the association between translation, linguistics theory, sociolinguistics and globalisation. It will focus on the different kinds of Language Planning and language aspects that influence or are influenced by languages such as economy, socio-political aspects, education, multilingualism as a resource or problem, language shift, death and development.
Linguistics Theory
The course examines the theoretical framework of African Languages especially the grammatical descriptions. It seeks to explore the meaning and use of the languages. Comparative studies will be part of the course. Knowledge on the broad understanding of issues in language will be imparted. It will explore the various aspects of unconscious linguistics knowledge. Students will be expected to give an in depth understanding of language skills especially in communication.
This course deals with all the genres of isiXhosa Literature. It aims to impart knowledge on the analysis of novels, short stories, essays, drama, and poetry. Students will be introduced to a variety of books associated with these genres.
Introduction to Lexicography and Terminology
The aim of this course is to introduce language students to the disciplines that underpin one of the fundamental resources of the practising linguist: the dictionary, in all its forms*. This is intended to be a practical course, which will align theoretical background with hands-on experience of both using and preparing lexicographic and terminological materials for applied language activities such as translation, interpretation, writing and editing.
*In this context, the word 'dictionary' is used generically to cover all types of word lists, term lists, and glossaries.
This degree is offered by a thesis on any approved topic to full or part time students. It caters for candidates who hold a Post Graduate degree in any African Language, students holding an ordinary degree will be accepted in exceptional cases. When the candidate's subject of research has been approved, such approval will remain in force so long as the annual registration fee is paid. Candidates are expected to report in person to their supervisors from time to time and these candidates should be registered for at least two years. Since this course is offered by theses the first step for these candidates is to write a research proposal by following the Higher Degrees Guidelines. Once the proposal has been approved by Higher Degrees Committee the candidate can continue with his/her research. For more information please refer to General Rules G.50 to G. 61 of the university calendar.
Last Modified: Tue, 28 Mar 2017 15:58:36 SAST


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For the third week in the row, the Cal women's swim team will take to the Spieker Aquatics Complex, but this time with a special guest: The Bears will swim in a dual meet with the men's swim team against Wisconsin on Friday at 1 p.m. The winners of the NCAA championships last year, the men's team may not feature the recognizable names the womens' does, but they have been much more successful winning championships, having won three in the last four years.
"I really like the chance to have a dual meet with the men's team because it brings a different kind of energy," said Cal associate head coach Kristen Cunnane. "It's a good learning experience to see them race and see what they are doing. Year in and year out, they are definitely one of the top teams in the country."
Cal will be swimming at home against Wisconsin for the third year in a row. The Bears won the past two meetings in dominant fashion, defeating the Badgers 163-111 last year and 170-110 in 2012. Wisconsin's head coach, Whitney Hite, was the assistant for Cal head coach Teri McKeever from 2004 to 2006.
The Bears are coming off a tough loss to Texas last week, 161-139. Cal was unable to close out the meet and ended up losing their early lead. Despite the loss, junior Elizabeth Pelton had a dominating performance, winning three individual events. Sophomore Missy Franklin also won two events, the 100-yard and 200-yard freestyle, finishing in 1:47.37 and 50.13, respectively.
"I think we definitely learned a lot from the Texas meet," Cunnane said. "We're going to take that and try to be a little be tougher, a little bit sharper."
Wisconsin (1-2) is coming into the meet off a loss against Minnesota, 95-203. In the meet, senior Ivy Martin won both the 50-yard and 100-yard freestyle and also placed second in the 100-yard butterfly. The Badgers won their first meet of the season Oct. 3, against Arizona State, 142-94, where they won 11 events.
Martin has the fastest 50-yard freestyle time in women's college swimming, 22.31. Martin is known for her sprinting abilities and could pose a potential problem for the Bears, who don't have a sprinter of Martin's caliber. Also for the Badgers, junior Jenny Holtzen has reached personal best times in the 500- and 1,000-yard freestyles. In fact, Wisconsin's fast start has included seven swimmers reaching new personal bests.
"Swimming against Wisconsin is always fun," Cunnane said. "(Hite is) definitely building an outstanding program at Wisconsin, so (we are) really grateful they will come all this way to race us."
Cal will not return back home until Jan. 30, so they hope to have a positive performance at home before they head on the road.
"I think just capitalizing on having the home crowd and the men there with us, capitalizing on that energy and taking into our racing," Cunnane said. "We are definitely hoping for a good home crowd; the weather is supposed to be really nice, swimming with the men's team will hopefully, get a bigger crowd and some more energy. We'll bring our energy, and it will be a good."
Alaina Getzenberg covers women's swim. Contact her at [email protected]


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I have developed a simple, manual process in hopes of increasing your email revenue using your MailChimp email campaigns. This process uses simple statistics to help you optimize your email scheduling and increase your Revenue. Before you begin, you will need to have at least 6 months of data using MailChimp for your eCommerce website.... Continue Reading →
Muttontown Preserve Ruins Documentary (Transcript)
I made a short documentary for a video class assignment in 2011 at SUNY Old Westbury. I enjoy hiking then and still do now. I picked the Muttontown Preserve because it is one of my favorite Long Island hiking spots. This was my first attempt at making a documentary.
Logo Design
Give your small business, band, or blog a unique icon used to communicate your brand across language barriers. A well-designed logo makes this possible. Make your brand stand out and recognizable with my logo design services.
Get Organized with Clover
(Icon for Clover) I love the tab function of macOS Sierra and higher for Mac's window panes because it allows me to get organized with my projects more easily. I thought to myself, "does Microsoft Windows have this functionality?" The short answer is "no, not naively (built-in)." However, after doing some Googling, I discovered the... Continue Reading →
Using Calculus to Determine Your Next Estimated Ordering Date for Paper #RealWorldCalculus
The following process described will not necessarily be 100% accurate as paper consumption varies year-round especially for seasonal businesses. For more accurate results, track paper consumption for a year (as described below).
Vector is Best For Logos & Graphics
The above graphic* is a good visual of the main difference between vector & raster. Raster images are what you naturally get with photos with file extensions such as JPG, PNG, TIFF. Vector file extensions include EPS, PDF**, and AI. Vector - created with mathematic equations by an app, independent from resolution. In other words,... Continue Reading →
Product Photography: My Process of Photo Compositing a 1-Tier PDQ Display into a 2-Tier PDQ Display
Behind the scenes look of my process in product photography, i.e. how I turn a 1-tier PDQ Display into a 2-tier PDQ Display: In graphic design and photography, the process of combining more than one photo or graphic into a single image is called "photo compositing." A company may need a multiple-tier PDQ display composited from... Continue Reading →
Cyber Security Tip – VirusTotal
Virustotal (https://www.virustotal.com) is a Google-owned site that you can use to scan & "analyze suspicious files and URLs to detect types of malware, automatically share them with the security community [aka Anti-virus/Anti-Malware companies]." If you suspect or are unsure about the how safe a link (URL), download, or file is, you can use Virustotal to scan... Continue Reading →
Cyber Security Tip – Password Manager Apps
Manage your passwords not in a Word doc but in a secure, encrypted password safe app


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Mid-July and the heat is here in Charleston! These days in the roastery, we're taking our coffee cold in the afternoons. One easy method we do often is brew Japanese Iced Coffee.
It's simple: coffee brewed hot over ice.
This flash-chilled method yields a delicate, light-bodied drink, more tea-like and subtle. It's not a coffee that you would add milk or sweetener too and it's one that we recommend using a lighter roast coffee. Easy to make and enjoyable, it's often our go-to for our afternoon coffee break.
For Japanese Iced Coffee, you will need:
Coffee: 24 grams
Grind: Medium- Medium-fine
Water: 230 grams. Hot and just off boiling
Ice: 200 grams
We recommend brewing in a Chemex or Hario Drip Decanter
Water-to-Coffee Ratio: 10-1
Brew time: approx. 2.5 minutes
Have you tried the brew method before? We'd love to know what you think!


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The home is used only as a conventional dwelling is currently transformed into a modern home with a range of designs and models vary. Moreover, it is also sustainable. Although it's not proper for the whole house, it's a fantastic choice for entertainment areas like pergolas and patios. The original house was designed in the 1930s in a traditional architecture style. Furthermore it would be better if the wooden home is built in an area which has good pure elements, including mountains, hills, and beaches. Wooden houses are extremely popular and modern in a some regions of the world. Surely wooden house located in urban residential locations and will earn a decrease in the value of art in the home. Read more "11 Most Creative Modern Wooden Houses of 2019"
Category: cambridge
20 EXSTRAORDINARY Designs of Modern Minimalist Old Houses
You're able to simply utilize Keynote templates designed by professionals to produce the ideal slideshow presentation in a couple of minutes. You can choose a retro minimalist design or go all out and receive a planet. Our present ecommerce web design was outdated and was not responsive. Read more "20 EXSTRAORDINARY Designs of Modern Minimalist Old Houses"
23 New Cambridge Home Designs are Suitable for Low Budget
Many truck owners would like to have service stations on either side of the truck so that they can maximize volume and support. Whether you're after an upcoming investment property, a house for the family members or a luxury establishment, we've got a variety of house plans and new home designs to suit your wants. An open home is a chance to walk through a home that's for sale without the should bring along a realtor. While wiring every room in your home for video might appear cool, it isn't necessarily a terrific investment. Employing a table permits you to modify the Grouping by altering the table and refreshing the PivotTable. The Order table, however, are going to have exceptional Order ID field. In many instances, a single data table doesn't have all the info you have to create your report. Read more "23 New Cambridge Home Designs are Suitable for Low Budget"


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CSU's Graduate Certificate in Ministry is a practice-oriented course and an excellent way for ministers to upskill as you reflect on your ministry practice.
The course comprises a single core subject on reflective practice in contemporary ministry, along with three electives. Electives permit you to explore such areas as pastoral counselling, supervision, church governance, management and leadership, applied pastoral theology, chaplaincy, and contemporary mission and evangelism.
This course is a pathway into the Master of Ministry. (Completion of this course awards you with 32 out of the 96 required credit points for the Master of Ministry.)
Our course advisors are well placed to match your background and educational objectives to the course that would best suit your needs.
Just fill out our online form and one of our course advisors will get in touch with you.Ask for a course advisor
The Graduate Certificate in Ministry aims to assist ministers and others in church leadership by providing skills in ministry to a range of contexts for professional practice.
The course aims to
Candidates for admission need to have
The Graduate Certificate comprises 4 subjects, beginning with a core subject that introduces reflective practice in contemporary ministry.
Students may then choose to study any 3 of the electives listed below. A full list of subjects and electives will be available on the CSU website late in 2018.


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Information Technology Services
Requesting a NetID (Username) Change
The display name for your various MSU Denver accounts (e.g. the part of your email address that appears before the @msudenver.edu) is called your NetID (Network ID). Changing a NetID can have some serious complications, including loss of coursework, corruption of student records, loss of email information (calendars, address book, etc.), and loss of emails. Additionally, any email sent to your old email address will be returned to sender stating there is no such address. Therefore, there must be a legal or urgent reason—such as a legal name change due to marriage or other reasons, or if the NetID is profane, illegible, or socially unacceptable—before the NetID will be changed.
After a legal name change, you must first obtain a new Social Security Card that displays your new name. If you are a student and your name has changed, you must take the new Social Security Card to the Registrar's Office in SSB 160 to request your name be changed in the system. If you are a faculty or staff member and your name has changed, you must take the new Social Security Card to Human Resources in SSB 310 to request your name be changed in the system. Only after your name has been officially updated in Banner can we begin the process to change your NetID.
Please be aware of the following:
- Due to the potential for loss of academic information, we do not process NetID changes for any student or faculty while they are taking or teaching classes. Anyone associated with an active, current-semester course must wait until after grades have been posted for the semester before submitting a change request.
- We anticipate this process taking up to a week to complete. We will contact you by phone when the process is complete to provide your new NetID and confirm you are able to log in to your MSU Denver accounts with the new information. We cannot provide login information via voicemail or email.
- Your new NetID will be generated automatically based on your name as it appears in the University database.
- During this process, you may lose access to MSU Denver web services, including email, Blackboard, and the Employee Services/Student main menu.
- Your existing emails will be migrated as part of this process. However, any emails sent or received by your MSU Denver account during the transition period may be lost.
If you have read and understand the implications, and would still like to have your NetID changed, you will need to submit a HelpDesk ticket stating:
- Your request.
- That you understand the above implications.
- That you would like to proceed with a NetID change.
Last Update: March 2019
Further Assistance
If you have additional questions, concerns, or need immediate assistance - Please contact the MSU Denver Helpdesk.


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How to help someone who may be experiencing domestic violence
It can be worrying if you suspect that someone you know may be experiencing domestic violence. If you are unsure whether your friend or relative is experiencing domestic violence., there may be some signs that indicate there may be domestic violence:
- They may be afraid of their partner or be always very anxious to please him or her.
- They may talk about their partner being possessive, or very jealous, or having a bad temper.
- They may have become anxious or depressed, or have their confidence, or be unusually quiet.
- They may have stopped seeing friends or family.
- They may always cut their phone calls short when their partner is in the room.
- They may have unexplained physical injuries such as bruises, broken bones, sprains, or cuts.
- You may have noticed that they are often criticised or humiliated by their partner in front of other people.
- Their partner may orders them around and make all the decisions for them (such as controlling what they can do, who they can see, and their money).
- They may be reluctant to leave their children alone with their partner.
How to help someone who has been sexually assaulted
If someone you know tells you they've been sexually assaulted, it can be really overwhelming. You'll probably have feelings of your own to deal with and might not think there's much you can do to help.
But there is a lot you can do. And it doesn't mean you have to have all the answers. Here's how you can help:
- Hear what your friend has to say and try not to interrupt.
- Your friend needs to know that you're on their side.
- Tell your friend that what they're feeling is ok.
- No blame. In our society it's common for victims to be blamed for the assault. Try to avoid questions like "why did you go there?" and "why did you drink that much?" because they might make your friend think that they are responsible for what happened. Victims are never to blame for their experience of sexual assault.
- If you're not sure, ask your friend what sort of help they'd like from you.
- Shhh… Your friend or family member trusts you and so if you think that someone else needs to know, tell your friend first.
- Get help. Encourage your friend to talk to someone for more support, such as a counsellor at the Canberra Rape Crisis Centre.
- If you need to talk to someone yourself, you can call the Canberra Rape Crisis Centre on (02) 6247 2525.
Services you can access
The Domestic Violence Crisis Service
The Domestic Violence Crisis Service gives priority to the safety of people who have been subjected to violence and abuse, but they also work with all people who have been affected by Domestic Violence.
The Domestic Violence Crisis Service can provide support for family and friends of those affected by domestic violence
The Canberra Rape Crisis Centre
The Canberra Rape Crisis Centre Support can provide support for family and friends of those affected by sexual violence and assault. CRCC is staffed by specially trained workers.
These services are free and confidential. Call (02) 6247 2525 7am to 11pm, 7 days a week for support, information.
Resources you can access
The Women's Legal Centre has published the following resources:
- Domestic violence: a friend's tale
- Domestic violence: a neighbour's tale
- Domestic violence: a sister's tale
You can download them at: http://www.womenslegalact.org/Publications/Resources
What to say! – A new tool for responding to sexual violence – for women and in the workplace.
The What to say website now includes two new sections – What to say for women and What to say for the workplace. These sections are designed to give women and co-workers the information they need to identify sexual violence, safe ways to respond and intervene if you experience or witness sexual violence, and advice on how to support someone who tells you they've experienced sexual violence. Each new section incorporates information about who to contact and will include regular blog posts over the summer about issues like sexual harassment, dating, work parties and nights out.