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Reference: HDMVA-135
Property Details
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Proximal 10q duplication in a child with severe central hypotonia characterized by array‑comparative genomic hybridization: A case report and review of the literature
- Authors:
Affiliations: Laboratory of Genetics, Eurogenetica S.A., Athens 11527, Greece, Department of Human and Hereditary Pathology, University of Pavia, Pavia 27100, Italy, Department of Gynecology, Larissa Medical School, University of Thessaly, Larissa 41335, Greece, Developmental Assessment Unit, Second Department of Paediatrics, P&A Kyriakou Children's Hospital, University of Athens, Athens 11527, Greece, Laboratory of Genetics, Bioiatriki S.A., Athens 11526, Greece, Department of Ophthalmology, University of Ioannina, Ioannina 45110, Greece, Institute of Human Genetics and Anthropology, Jena University Hospital, Jena D-07743, Germany
- Published online on: February 6, 2014 https://doi.org/10.3892/etm.2014.1520
- Pages: 953-957
This article is mentioned in:
Proximal 10q duplication is a well-defined, but rare syndrome and is often derived from a balanced translocation in a parent (1,2). In this study, the case of a boy with phenotypic abnormalities and duplication of the chromosomal region, 10q11.21→q11.22, characterized by the array-comparative genomic hybridization (CGH) technique, is reported. The phenotypic findings were compared with those in eight additional published cases with proximal partial duplication of the long arm of chromosome 10q (1–8). The partial proximal trisomy 10q consists of mild to moderate developmental delay, postnatal growth retardation, microcephaly, prominent forehead, small and deep set eyes, epicanthus, upturned nose, bow-shaped mouth, micrognathia, thick and flat helices of the ears and long, slender limbs (8). The present study concerns an 8-year-old boy with severe central hypotonia in whom array-CGH identified a de novo cryptic duplication of the proximal 10q.
Materials and methods
Conventional karyotyping based on GTG-banding (600–800 bands) was performed using standard methods on metaphases from blood leukocytes.
Molecular karyotyping was performed on DNA extracted from the whole blood of the patient and both parents. All the experiments were performed through oligo-array platforms (Human Genome CGH Microarray 44B Agilent kit; Agilent Technologies, Santa Clara, CA, USA). Briefly, 500 ng of proband and of a gender-matched pooled reference DNA (Promega Corporation, Fitchburg, WI, USA) were processed according to the manufacturer's instructions. Fluorescence was detected in a dual-laser scanner (DNA Microarray Scanner with Sure Scan High-Resolution Technology; Model G2565CA; Agilent Technologies) and the images were extracted and analyzed through Agilent Feature Extraction software (v10.5.1.1) and DNA Analytics software (v4.0.73) (Agilent Technologies). Changes in test DNA copy number at a specific locus were observed as the deviation of the log2ratio value from the value of 0 of at least three consecutive probes. The quality of each experiment was assessed using a parameter provided by Agilent software (QC metric) and on the basis of DNA quality. Copy number changes identified in the samples were compared with the Database of Genomic Variants (http://projects.tcag.ca/variation/) and also visualized using the UCSC Genome Browser website (http://genome.ucsc.edu/). Moreover, DECIPHER (http://decipher.sanger.ac.uk/) and ECARUCA (http://umcecaruca01.extern.umcn.nl:8080/ecaruca/ecaruca.jsp) databases were used for comparison with possible analogous reported cases. The positions of oligomers referred to the Human Genome March 2006 assembly (hg18).
Fluorescence in situ hybridization (FISH) analysis
FISH experiments were performed on metaphase spreads using the following as probes: Bacterial artificial chromosomes (BACs) for the chromosomal region 10q11.22 (RP11-292F22 located in 47.075–47.114 Mb, as obtained from the Children's Hospital Oakland Research Institute, Oakland, CA, USA) and chromosome 10 centromeric probe (cep 10; Kreatech Diagnostics, Amsterdam, Netherlands). Ten metaphase spreads were analyzed for each FISH experiment. Analysis was performed using a Zeiss epifluorescent Axioskop 2 Plus microscope (Carl Zeiss Microscopy, LLC, Thornwood, NY, USA), and images were captured, enhanced and analyzed using Cytovision (Leica Biosystems, Wetzlar, Germany) software.
Case report
The patient was a 3-year-old boy, the only child of healthy non-consanguineous parents of Greek origin (a 38-year old father and 33-year old mother at the time of birth) with unremarkable family history. The prenatal serial ultrasound examinations were reported as normal and the pregnancy was uneventful. The patient was born at 40 weeks of gestation by vaginal delivery. The Apgar scores were 8 at 1 min and 9 at 5 min. The birth weight was 2,950 g (10th centile), the birth length was 50 cm (50th centile) and the occipitofrontal circumference was 3 cm (25th–50th centile).
At 8 months the patient responded normally to age appropriate communication stimuli and parental overtures; however, he exhibited severe central hypotonia, mild ataxia and mild dysmorphic features, such as a triangular face, an enlarged cranium cerebrale, a bifid scrotum, cryptorchidism, ulnar deviation of both elbows, singe palmar creases of hands and syndactyly of the second and third toes bilaterally. Brain magnetic resonance imaging revealed hypoplasia of the corpus callosum and benign dilatation of the subarachnoid areas, while G-banding karyotyping along with detailed haematological, biochemical and metabolic examinations showed no pathology. Physiotherapy was initiated and the patient walked unaided at the age of 18 months. At 19 months, the cryptorchidism was surgically corrected. The patient first uttered words and two-word phrases at the ages of 23 and 27 months, respectively.
At 2 years and 7 months, a referral for developmental assessment was made due to language delay. The patient was a sociable boy with mild dysmorphic features that could easily have passed unnoticed, such as a triangular face, frontal bossing, micrognathia, slight auricle abnormalities, a high-arched palate, pectus carinatum, widely spaced nipples, a mild systolic murmur and a clubfoot. The patient was 15 kg (75 centile) in weight and 98 cm (90th centile) in height, and had a head circumference of 52 cm (90th centile). The developmental abilities of the patient were equivalent to the level expected at 22 months, while the patient's speech consisted of 40 words and a few two-word phrases. Visual, hearing and heart ultrasound examinations were normal and speech therapy was initiated.
A re-evaluation was conducted at the age of 3 years. Clinical examination revealed a sociable boy with mild facial abnormalities (frontal bossing, moderate micrognathia, a gothic palate and auricular abnormalities), pectus carinatum, widely spaced nipples, a mild systolic murmur, single palmar crease and a clubfoot. The developmental abilities of the patient were further improved, being equivalent to the level at 2 years and 5 months. According to Griffiths Scales of Mental Abilities his developmental quotient was 82 (9). The patient was 17 kg (75–90th centile) in weight, 98 cm (75th–90th centile) in height and had a head circumference of 53 cm (90th–97th centile). Neurological examination revealed truncal hypotonia, but without focal signs. Informed consent was obtained from the patient's family and the study was approved by The Second Department of Paediatrics, University of Athens, P&A Kyriakou Children's Hospital, Athens, Greece
The karyotype analysis of the proband identified a normal karyotype, 46XY, and chromosome analyses of both parents were also normal. Array-CGH analysis revealed a 5.6-Mb duplication in the long arm of chromosome 10 located in the 10q11.21→q11.22 region (Fig. 1). The proximal breakpoint was observed between 45.478 and 46.568 Mbp and the distal breakpoint was between 51.264 and 51.676 Mbp. No abnormal copy number variations were identified in either parent using array-CGH technology. The DECIPHER and ECARUCA databases were used as resources to aid the genotype-phenotype correlation analysis. The duplication was confirmed by FISH analysis as shown in Fig. 2.
Figure 1
Array-CGH profile of chromosome 10 showing an interstitial duplication. (A) View of chromosome 10 and (B) the enlarged view of the rearrangement as generated by Agilent Technologies, CGH Analytics 4.0.73. The proximal duplication breakpoint was between 45.478 and 46.568 Mbp, and the distal duplication breakpoint was between 51.264 and 51.676 Mbp. The overall size of the duplication was ~5.6 Mb.
Figure 2
FISH analysis to confirm duplication. The analysis was performed using the probes RP11-292F22 in 10q11.22 and cep10 (centromeric probe). The resultant pattern indicated that chromosome 10 has an interstitial duplication on the proximal 10q arm. FISH, fluorescence in situ hybridization.
Proximal 10q duplication is a well-defined but rare genetic syndrome, often derived from a balanced translocation in a parent. The partial proximal trisomy 10q consists of mild to moderate developmental delay, postnatal growth retardation, microcephaly, a prominent forehead, small and deep set eyes, epicanthus, an upturned nose, a bow-shaped mouth, micrognathia, thick and flat helices of the ears and long, slender limbs (1–8).
The present study concerns the case of a 3-year-old boy with phenotypic abnormalities and severe central hypotonia in whom array-CGH resulted in the identification of a de novo cryptic duplication of the proximal 10q (10q11.21→q11.22). This is the first case of partial proximal trisomy 10q characterized by array-CGH. To the best of our knowledge, only eight cases have previously reported duplication at 10q11→10q22 (1–8). The clinical characteristics of the eight previously published cases with duplication at 10q11→q22 and the present case are outlined in Table I. In concordance, the patient of the present study showed severe central hypotonia, ataxia, a triangular face, frontal bossing, moderate micrognathia, slight auricular abnormalities, a high-arched palate, an enlarged cranium cerebrale, pectus carinatum, widely spaced nipples, a mild systolic murmur, a bifid scrotum, cryptorchidism, ulnar deviation of both elbows, single palmar creases of the hand and foot, as well as clubfoot and syndactyly of the second and third toes bilaterally. The current case did not show growth retardation and microcephaly, which have been considered common features of the syndrome (1–5,7–8). Similarly Lam et al (6) reported a case with proximal trisomy 10q, but without the phenotypic features of microcephaly.
Table I
Summary of the clinical features in previously published cases with partial proximal trisomy 10q syndrome and the present case.
The patient of the current case presented with brain malformations, which have not been identified thus far, while Lysy et al (8) reported a patient who presented with biliary atresia, anal anteposition and cardiac malformations.
Notably, these cases may be clearly distinguished from the cases with duplications of 10p12.1 to 10q11.22 (10). Liehr et al (10) identified a novel unbalanced region of chromosomal abnormalities in the pericentromeric region of chromosome 10 (10p12.1 to 10q11.22), which did not have negative phenotypic consequences.
The duplicated region identified in the present case spans only ~5.6 Mb of genomic DNA and contains ~36 genes with variable functions. Specifically these genes encode regulators of membrane organization and membrane trafficking [annexin A8 (ANXA8), ANXA8L1 and ANXA8L2], morphogenetic proteins and regulators of cell growth and differentiation [growth differentiation factor 2 (GDF2) and GDF10), transcription factors and modulators [dorsal root ganglia homeobox (DRGX)], signal transducers [mitogen-activated protein kinase 8 (MAPK8)], enzymes [choline acetyltransferase (CHAT) and poly(ADP-ribose) glycohydrolase (PARG)] and DNA repair proteins [excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6)]. It is worth taking into consideration that studies in rodents have suggested that the proteins, GDF2 and GDF10 are important in the differentiation of cholinergic central nervous system neurons and in skeletal morphogenesis, respectively (11,12). It is possible that the emerged severe phenotype is due to the fact that the region includes major genetic information affecting physical development, or that the duplication significantly alters the expression pattern of the corresponding genes.
Further studies are required to elucidate the pathogenic mechanisms as more cases are likely to be identified with 10q proximal duplication, which may be characterized by the advanced methodology of array-CGH. The critical region of the 10q duplication syndrome will be identified more specifically by including benign cases with duplication of 10p12.1 to 10q11.22.
Vogel W, Back E and Imm W: Serial duplication of 10 (q11 leads to q22) in a patient with minor congenital malformations. Clin Genet. 13:159–163. 1978. View Article : Google Scholar : PubMed/NCBI
Fryns JP, Kleczkowska A, Igodt-Ameye L and Van den Berghe H: Proximal duplication of the long arm of chromosome 10 (10q11.2 → 10q22): a distinct clinical entity. Clin Genet. 32:61–65. 1987.PubMed/NCBI
De Michelana MI and Campos PJ: A new case of proximal 10q partial trisomy. J Med Genet. 28:205–206. 1991.PubMed/NCBI
Aalfs CM, Hoovers JM, Nieste-Otter MA, Mannens MM, Hennekam RC and Leschot NJ: Further delineation of the partial proximal trisomy 10q syndrome. J Med Genet. 32:968–971. 1995. View Article : Google Scholar : PubMed/NCBI
van Buggenhout G, Decock P and Fryns JP: A distinct phenotype associated with partial trisomy 10q due to proximal direct duplication 10q11→q223? Genet Couns. 7:53–59. 1996.PubMed/NCBI
Lam FW, Chan WK, Lam ST, Chu WP and Kwong NS: Proximal 10q trisomy: a new case with anal atresia. J Med Genet. 37:E242000. View Article : Google Scholar : PubMed/NCBI
Nucaro A, Faedda A, Cao A and Boccone L: Partial proximal trisomy 10q syndrome: a new case. Genet Couns. 13:411–416. 2002.PubMed/NCBI
Lysy PA, Sibille C, Gillerot Y, Smets F and Sokal EM: Partial proximal 10q trisomy: a new case associated with biliary atresia. Hereditas. 144:191–194. 2007. View Article : Google Scholar : PubMed/NCBI
Griffiths R: The Abilities of Young Children. Bucks: Association for Research in Infant and Child Development. A comprehensive system of measurement for the first eight years of life. The Test Agency; Thames: pp. 101–172. 1984
Liehr T, Stumm M, Wegner RD, Bhatt S, Hickmann P, Patsalis PC, Meins M, Morlot S, Klaschka V, Ewers E, Hinreiner S, Mrasek K, Kosyakova N, Cai WW, Cheung SW and Weise A: 10p11.2 to 10q11.2 is a yet unreported region leading to unbalanced chromosomal abnormalities without phenotypic consequences. Cytogenet Genome Res. 124:102–105. 2009. View Article : Google Scholar
López-Coviella I, Berse B, Krauss R, Thies RS and Blusztajn JK: Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9. Science. 289:313–316. 2000.
Cunningham NS, Jenkins NA, Gilbert DJ, Copeland NG, Reddi AH and Lee SJ: Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3. Growth Factors. 12:99–109. 1995. View Article : Google Scholar : PubMed/NCBI


text:
Slightly Cooler Start, Warm Middle of the Week
From Meteorologist Zack Webster in the 4Warn Storm Center:
SYNOPSIS – Mostly sunny skies continued to stick around the Wiregrass this afternoon. Temperatures once again made their way into the middle to upper 70s. We'll trend a little bit cooler for Monday as a weak cold front pushes through. Highs will rebound back into the middle to upper 70s for most of the week ahead. We'll see a chance of rain late Wednesday into early Thursday, then again on either Saturday or Sunday as a pair of cold fronts move through.
TONIGHT – Mostly clear. Low near 55°. Winds N at 5 mph.
TOMORROW – Sunny. High near 74°. Winds N at 10 mph.
TOMORROW NIGHT – Clear with some high clouds. Low near 49°. Winds N, turning E at 5 mph.
TUE: Sunny with some high clouds. Low: 51° High: 77°
WED: Partly sunny, isolated evening showers and thunderstorms. Low: 58° High: 79° 40% PM
THU: Overnight storms, then partly cloudy with a slight rain chance. Low: 58° High: 75° 20%
FRI: Partly cloudy. Low: 55° High: 76° 10%
SAT: Partly sunny with isolated showers and thunderstorms. Low: 56° High: 73° 30%
SUN: Mostly cloudy with scattered showers and thunderstorms. Low: 55° High: 71° 50%
COASTAL FORECAST MONDAY – Light chop on Coastal Lakes and Bays. Winds N at 10-15 kts. Seas 1-2 feet.
4Warn Weather Team on Social!
@MetDavidPaul, @ZackWebWx
WTVY 4Warn Weather Team, Chief Meteorologist David Paul, Meteorologist Zack Webster
Copyright 2020 WTVY. All rights reserved.


text:
Emoji - My Moji Maker
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text:
Vinny Tumulty is a quiet, sensible man. When he goes to stay at a seaside town, his task is to comfort a bereaved friend. Vinny is prepared for a solemn few days of tears and consolation. But on the evening of his arrival, he looks out of the window at the sunset and catches sight of a mysterious, romantic figure: a beautiful woman walking by the seashore. Before the week is over Vinny has fallen in love, completely and utterly, for the first time in his middle-aged life. Emily, though, is a sleeping beauty, her secluded life hiding bitter secrets from the past.
Año de publicación:1970
No hay reseñas aún, sé el primero en reseñar este libro.
Calificación General:9,0
Calificación General:9,6
Calificación General:7,9


text:
Pursuant to Gov. Bill Lee's statewide "Stay at Home" order, Executive Order #23, issued on Thursday, April 2, 2020, Bowie Nature Park and all City of Fairview Parks are currently closed until orders by Gov. Lee are lifted.
Gov. Lee signed Executive Order 23 requiring that Tennesseans stay home unless they are carrying out essential activities. The executive order remains in effect until April 14, 2020 at 11:59 p.m.
More Coronavirus News
- COVID-19 Cases Among Children November 29, 2020
- Williamson County Coronavirus Case Count November 29, 2020
- Total Coronavirus Case Count in Tennessee November 29, 2020
- Hospital Leaders Write Appeal to Tennesseans Regarding COVID-19 November 24, 2020
- COVID-19 Dashboard: New Cases in Schools November 24, 2020
- Metro Nashville Schools Returning to All-Virtual Learning After Thanksgiving November 24, 2020


text:
Weather warnings
Asset Publisher
Aviso Meteorológico IMN 231020 1100 am
Weather Warning
Downpours and storm this Friday
October 23, 2020
11.00 a.m.
Diagnosis: The high temperatures that have been registered this morning, added to the flow of humidity from the Pacific and the activity of the Convergence Zone, creates conditions for the formation of highly developed clouds and thus increases the probability of heavy rains and storms this late.
Forecast: For this afternoon and first hours of the night, the regions of the North Pacific, Central Valley, North Zone and mountainous parts of the Caribbean present a high probability of showers with thunderstorms.
In particular, the Nicoya peninsula, the plains in the North Zone, the east and south of the Central Valley, and the mountainous parts of the Central and South Pacific are the areas where the strongest activity is expected to occur. The maximum amounts estimate between 40-85 mm.
In the case of the coastal Caribbean, it is expected to be very stable, with a partially cloudy sky and a low probability of rain.
Warning: Special attention due to the high percentage of soil saturation in the Nicoya Peninsula and Northern Zone.
Due to the above, the IMN recommends:
• Caution in areas vulnerable to flooding due to sewerage saturation.
• Take shelter in a safe place in case you hear an electrical storm or perceive strong gusts of wind near the storm clouds, as well as caution against possible falling tree branches, power lines, among others.
• Stay informed through social networks, Twitter: @IMNCR, Facebook: Instituto Meteorológico Nacional CR and the WEB Page: www.imn.ac.cr
Gabriela Chinchilla
Everyone at some point have directed the view to the sky and observed the clouds. You have seen them dark, white, thin, dense, others that produce thunderstorms, lightning, hail and up to imagine well known figures.See more
The National Meteorological Institute, offers a range of services that can be ordered online in the next section of the site.go to services


text:
Date: October 25, 2020
Bible Text: 2 Chronicles 20 | Jason Smith
Series: Worship
Growth Group Discussion Questions
- What stood out to you from the sermon?
- We saw Jehoshaphat turn to God and pray during a critical moment. Can you think of other Biblical examples who turned to God in times of crisis?
- When life is at its crucial moments, do we truly turn to God, or do we tend to start by relying on our own stregth, wisdom, etc.?
- Read 2 Chronicles 20:12. What steps can we take to have a prayer life with the absolute humility portrayed by Jehoshaphat?
- Do you normally pray Scripture, pray the promises of God back to Him?
- How does praying the promises of God impact your prayer life?
- Pastor Jason gave the anology of coming to a football game prepared (noise makers, dressed up, etc.) as we believe the crowd affects the game. How can we come better prepared to worship like it matters?
- When we sing, how can we be more attuned to thinking about the promises of God that we are singing about?
- Spend a few minutes reading the following passages and praying the promises back to God. (Nehemiah 8:10, Matthew 6:33, 1 Corinthians 10:13, 2 Corinthians 4:8-9, Ephesians 6:11, Philippians 4:7, James 1:5, and 2 Chronicles 7:14)
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Ever need an extra burner during holiday cooking? Having company and need to keep something warm? Do crafts and not want to mess up your kitchen? The Better Chef Electric Buffet Range is just the ticket! This burner features an adjustable temperature thermostat control to ensure you cook your next great meal at just the right temperature. This cooktop will add a sleek look to your kitchen.
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Motorists need to be on the lookout for deer on the run now that Michigan's firearm deer season has officially begun.
"As hunters head into fields and forests, deer will become more active – especially at dawn and dusk – and it's important for drivers to keep their eyes peeled for deer that might dart out in front of cars," said Erin McDonough, executive director of Insurance Alliance of Michigan (IAM), in a news release Monday. "As driving habits return to pre-pandemic levels, data has shown an increase in more serious crashes, which is another reason why it's so important for drivers to watch for deer this fall."
The worst time for drivers is between 6 p.m. and 9 p.m., according to data from the Michigan State Police. Also important to note is many of the crashes involving deer happened on the same stretch of road.
The counties with the most reported vehicle crashes involving deer in 2019 were:
Oakland County (1,928)
Kent County (1,684)
Jackson County (1,630)
Lapeer County (1,394)
Ottawa County (1,288)
Sanilac County (1,226)
Genesee County (1,212)
Allegan County (1,210)
Calhoun County (1,195)
Clinton County (1,174)
In 2019, 1,429 people were injured, and 12 people were killed in 55,531 crashes involving deer in Michigan. That's up from 2018, when 53,464 vehicle crashes involving deer were reported resulting in 1,200 injuries and 14 deaths.
"Deer travel in groups, so it's critical to remember that if you see one near the side of the road or in a field nearby there's a good chance more aren't far off," McDonough said. "Deer can dart out in front of cars without warning and are easily startled, which makes it hard to predict which direction they'll run and when. That's why you have to be prepared."
Firearm deer season began Sunday and runs through Nov. 30.
Driving tips
IAM recommends the following safety tips for motorists traveling during deer season:
• Watch for deer, especially at dawn and dusk, when they are most active. If you see one deer, approach cautiously, as there may be more out of sight.
• Deer often travel single file, so if you see one cross a road it's likely more are nearby waiting to cross. When startled by an approaching vehicle, deer can panic and dart out from any direction.
• Slow down when traveling through deer-populated areas.
• Always wear your seat belt.
• If a crash with a deer is unavoidable, don't swerve. Instead, brake firmly, hold onto the steering wheel with both hands, come to a controlled stop and then proceed to steer your vehicle off the roadway.


text:
Seedling ID x2
The7thLegend, in DISCUSSING PALM TREES WORLDWIDE
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Hi everybody!
I have a serious problem with germination of the coconuts. Many coconuts start to rot during the germination (some seedlings survive only). The surface of the coconuts and the embryo are covered with the white fuzzy / powder mold. I realize that the germination of the coconuts from the supermarkets is often associated with a high risk of failure, but if it is possible, I would at least want to minimize the formation of the molds on the coconuts. Since I grow the coconut palms indoor (I have a large south window where I grow my coconut palms for several years), I would like to use some natural (not chemical) fungicides. So far, I've only tried potassium permanganate, but it didn't help. What other natural fungicide do you recommend? I read on the internet that some natural products can be effective, such as: cinnamon, hydrogen peroxide, ethanol (short-term action only), seasalt water (coconut palms tolerate it highly), baking soda and liquid grapefruit seed extract (GSE). At the moment I don't have the opportunity to experiment with all the possibilities, so to make my situation easier, I want to ask you: Which natural product has the best fungicidal effects to kill the white fuzzy / powder molds?
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One of the most recognisable icons of Singapore is the Supertrees at Gardens by the Bay. One of the best ways to experience them is by taking a walk along the OCBC Skyway at the Supertree Grove.
The OCBC Skyway is a 128 metre-long aerial walkway, suspended 22 metres above ground. It provides a connection between two Supertrees and offers magnificent views of the Marina Bay area.
It is a ticketed attraction at Gardens by the Bay and one of the most amazing suspension bridges in Singapore.
Visiting the OCBC Skyway at Gardens by the Bay
HOLIDAYS: Exciting Holiday Camps & Workshops for Kids
READ: Discover Exciting Things to Do During the Year-end 2020 in Singapore
BIG CHRISTMAS GIVEAWAY: Take Part for a Chance to Win Amazing Prizes
Before heading over to the OCBC Skyway, be sure to purchase an entry ticket first.
After showing your ticket at the entrance to the OCBC Skyway, take an elevator up from the base of the Supertree to the suspended walkway.
The lift to the OCBC Skyway will take you up the equivalent of three storeys or the height of a forest canopy.
OCBC Skyway: Elevated Walk Amongst The Supertrees
The arcing walkway will provide you with a wonderous perspective of the Gardens. You can get an upclose look at the majestic Supertrees and the beautiful flora that covers their façade.
These vertical gardens serve many functions such as harnessing solar energy, acting as air intakes and collecting rainwater.
The two largest Supertrees also help to hold up the OCBC Skyway.
The other draw for visitors to the Skyway is the panoramic view that it provides of Gardens by the Bay. The only attraction which is higher than the Skyway is the Supertree Observatory.
Take note that as a suspended walkway, you will be able to occasionally feel the OCBC Skyway move under your feet.
OCBC Skyway Timing
The OCBC Skyway is open throughout the day and into the night, from 9 am to 8 pm. This makes it a mesmerising spot to be able to take in the twinkling lights of Garden Rhapsody, the light show at the Supertree Grove.
Find out more about the OCBC Skyway, including the latest costs and admission rates, at the Gardens by the Bay website.


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Komplete Kontrol S49 MK2
1 of 1
Komplete Kontrol S49 MK2
a day
a week
a month
SE16 (London)
Versatile keyboard controller with VST integration. The Native Instruments Komplete Kontrol S49 MK2 is a premium-grade, innovative MIDI keyboard controller, building on the success of the original Komplete Kontrol series. The Native Instruments Komplete Kontrol MK2 sees an improved design and an upgraded layout, including dual high-resolution colour screens for quick and easy navigation. The 49-n...ote Fatar keybed with Aftertouch provides exceptional realism and fluidity, thanks to its semi-weighted keys. The Komplete Kontrol MK2 Keyboard provides seamless integration with Maschine hardware and software, as well as many popular DAWs. It features a range of dedicated transport buttons as well as pre-mapped control of Komplete instruments and NKS instruments. Additionally, the Komplete Kontrol S49 MK2 MIDI Controller comes with Komplete 12 Select - a collection of some of the most popular virtual instruments and FX from Native Instruments.
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£20 per day
Press the down arrow key to interact with the calendar and select a date. Press the question mark key to get the keyboard shortcuts for changing dates.
Press the down arrow key to interact with the calendar and select a date. Press the question mark key to get the keyboard shortcuts for changing dates.
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Fluoxetine is a type of antidepressant known as an SSRI (selective serotonin reuptake inhibitor). It usually takes 4 to 6 weeks for Fluoxetine to work. Common side effects include feeling sick (nausea), headaches and trouble sleeping. They are usually mild and go away after a couple of weeks. If you and your doctor decide to take you off Fluoxetine, your doctor will probably recommend reducing your dose gradually to help prevent extra side effects. Fluoxetine is called by the brand name Fluoxetine.
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White Bear Hat (USA Shipping)
The Animal Hat provide fun and warmth all season long and make a perfect gift. The soft material provide extra comfort and cozy experience. You can wear this animal hat with leather pants, jeans, velvet skirts or prints, with nearly any style of clothing and footwear. Not only functional headwear, the hat has cute animal expressions.
Bear Hat Product Details:
Material: Soft
Sized for Kids /Teens and Adults. Qty-1
USA Shipping- Please allow 3 to 5 business days for delivery.
Shipping outside USA- Please check our other animal hats


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Search from Over 2500 Cities - All India
Top Localites to Buy Property
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Real Estate Agent In Top Localites
Valuable land suitable for hotel, Shop, garrage naear Sonapetia Toll gate on NH 41 i.e. Kolaghat .. Read More
Posted on : 25 Oct, 2020
Owner : SOUMEN KUMAR GHORAI
This property mainly situated in Digha road side area and front of plot have one way that is .. Read More
Posted on : 16 Sep, 2020
Owner : SUMAN ADAK
Total hi land,all over side boundry wall,Gate and entrance ready,beside NH 116,Commercial plot
Posted on : 28 Aug, 2020
Agent : TAMRALIPTA REAL ESTATE
URGENT Sale.. 10 acre Commercial land on Tajpur Main Road. Also available in 1 acre size. First .. Read More
Owner : Pradip Som
I have a land near kolaghat bridge on nh6 road. The front area of land 51 feet width . This .. Read More
Owner : RAJSHEKHAR GHOSH
Situated in the main township; corner plot. Square land measuring 86 decimal (@Benegara) do .. Read More
Owner : sakhya sekhar bhattacharjee
6 Acre Bastu Land with Bounday Wall
Owner : Animesh Samanta
This property is on the connector road side of NH 6. Road side property. From NH 6, distance .. Read More
Owner : anirban sarkar
92 Decimals (i.e. 36,800 sq ft) of land, located by the side of National High way (nh 60) with .. Read More
Owner : Shambo Sen
Land and Plots of Different Sizes Available At Tajpur. No Minimum Requirements.
Owner : Somnath
The Land Is Situated Near Mondarmmoni In Purba Medinipur,west Bengal. The Area Is Approximately .. Read More
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Land and Plots of 2-10 Bigha Old Digha and New Digha Available for Sale Digha Salt Lake Starting .. Read More
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Industrial plot in Haldia, West Bengal, located approximately 3 kms from the port; On hpl link .. Read More
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Mandarmoni is a seaside resort village in the East Midnapore district and at the northern end .. Read More
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1.5 Bigha Commercial Lands & Plots for Sell at Medinipur.
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30 Bigha Commercial Lands & Plots for Sell at Jhargram.
Owner : Shyamal Ghosh
The Warehouse is Fully Rcc Built, Situated On National Highway No.41, 4 Km Away from Haldia .. Read More
Owner : Francis Xavier


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MICA will leverage CINA Head AI algorithms to detect stroke and neurovascular emergencies
The type and amount of information possibly accessed varied by location
SmartXR helps radiographers capture quality images without needing to retake them
Clinsights platform will manage fleets of Canon MR, CT and Vascular lab solutions
Part of a collaboration with CyberMDX, a connected medical device security company
How can radiologists ramp up responsibly? How will imaging be different in a post-pandemic world?
Understanding the incentives for bringing imaging where it's needed most
Opening session emphasizes humanity in face of pandemic, other challenges
The following are just some of the products and services that will be on display at the virtual meeting
Emotions can run high in radiology, here are some tips to sooth them
December 01, 2020
December 01, 2020
December 01, 2020


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Shots: The approval is based on two clinical trials (P-III FINCH and P-II DARWIN) programs assessing Jyseleca in 3,500+ patients across a range of RA patient populations, including patients new to treatment and those who have demonstrated inadequate response to treatment with SOC including biologic DMARDs. Gilead and Eisai will jointly commercialize Jyseleca across Japan […]Read More
Tags : Jyseleca
Shots: The CHMP's positive opinion is based on P-III FINCH and P-II DARWIN programs that included 4,544 RA patient-years of experience with filgotinib. All three FINCH trials involve a broad range of patients that met their 1EPs In the trials, the drug achieved ACR20/50/70 and DAS28(CRP)<2.6. Moreover, Filgotinib inhibited the progression of structural joint damage […]Read More


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Published September 25, 2020
By Common Dream
The Trump administration on Friday moved closer to its goal of stripping conservation protections from the nation's largest national forest, putting over 9 million acres at risk of clear-cut logging and bulldozing for roads and sparking warnings of "irreversible ecological consequences."
"Forests are our guardians in our fight against the climate crisis, and we need forest protections more than ever if we are to avoid the worst impacts of the growing climate emergency."
—Amy Moas, Greenpeace USA
The proposal targets southeast Alaska's Tongass National Forest, which is described as "the crown jewel of the National Forest System" and "the still-thumping heart of a rainforest that once stretched uninterrupted from Northern California through Oregon, Washington, British Columbia, and Alaska."
"Of all the things our federal government could be devoting resources toward in 2020, slashing a rule to make way for clear-cutting in one of the world's last intact temperate rainforests shouldn't rank as a priority," said Kate Glover, Juneau-based staff attorney with Earthjustice.
The plan "would revert a net total of 168,000 old-growth acres and 20,000 young-growth acres previously identified as unsuitable timber lands to suitable timber lands," the EIS states.
A record of decision finalizing removal of the Roadless Rule is expected in 30 days.
Greenpeace USA senior forests campaigner Dr. Amy Moas warned that the "move by the Trump administration has irreversible ecological consequences, and sets a dangerous precedent for timber industry lobbyists and politicians in other states to secure access to our prized wild places."
"What's more," she added, "a healthy Tongass is essential to the wellbeing of Alaska Natives, the local economy in Southeast Alaska, and an abundance of wildlife."
Indeed, the forest is key habitat for species including bears, wolves, and salmon and essential to the food security and way of life for the Tlingit, Haida, and Tsimshian peoples.


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About Us
Online Courses
January 25, 2018
Dr. Estrella Delgadillo, N.D.
Apparently, Food Labels Aren't the Only Labels We Should Be Reading
It is no secret that we live in a toxic environment, so if you want to limit your toxic exposure, it is imperative that you read the labels of household products. I am very persistent about reading both...
January 18, 2018
People often express their opinion about how much money it cost to buy healthy food, but those same people will have no problem dropping $200.00 on an electronic device, Coach purse or a hair do. Ladies and gentleman, you know who I...
January 17, 2018
Essential Oils: Cost Effective Home Remedies
January 3, 2018
Correction: Request A Test. www.requestatest.com
January 2, 2018
Monitoring Your Health Is Not A Crime
Have you ever had a moment when you didn't feel well, but couldn't get a doctor's appointment for weeks to come. So many people have been telling me about how they don't have enough money to go to the doctor's office. Deductibles ar...
December 31, 2017
2018: Remodel Your Lifestyle
Start making healthier lifestyle choices. Whether it's a new relationship, new health habits, or new personal goals, learn the secrets to mastering optimal health. Look Good, feel better, think better, and work better! We can help you stay...
December 28, 2017
Cost Effective Home Remedies: Activated Charcoal/Plant-Based Diet
Do you realize a deficiency in B12 can mimic symptoms of Alzheimer's or Dementia. A close friend of mine was exhibiting the following symptoms: forgetfulness, flat effect, sometimes he was there physicall...
December 27, 2017
Eat Healthy & Live
Plant-Based foods (PBFs) consist of vegetables, fruits, nuts & seeds, legumes, and grains. When eaten in their natural form, they provide the most nutrient-rich supply of vitamins and minerals. Research indicates that PBFs are beneficial to...
December 24, 2017
H-pylori, is a spiral-shaped gram-negative bacteria, which characteristically latches on to its subject with deep penetration and consequently destroys the lining of the intestinal tract by initiating the inflammatory response. This damage compromises digestion and imp...
Essential Oils: Cost Effective Home Remedies
Diabetic Foot Care


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Sat 31st Oct 2020 - Second lockdown means hospitality needs a lifeline to survive the winter
Second lockdown means hospitality needs a lifeline to survive the winter:
The hospitality sector needs a lifeline to survive the winter, a trade body has argued after PM Boris Johnson announced a second national lockdown will start on Thursday. A spokesman for UKHospitalty said: "The costs to hospitality businesses of a second lockdown will be even heavier than the first, coming after periods of forced closure, the accumulation of mass debt and then significantly lower trading due to the restrictions of recent weeks. The sector was hit hardest and first, and this recent shutdown will hurt for months and years to come. The extension of furlough for a further month does help to protect our workforce during this difficult time. If hospitality, the sector that is our country's third largest employer, is to survive and help drive economic recovery, it will need equivalent – or more – support than that of the first lockdown. Hospitality businesses have already been pushed to the limits, with many closures already. For those that have survived, viability is on a knife edge, as is the future of the tens of thousands of businesses and hundreds of thousands of jobs that depend on hospitality, including through its supply chain, right across the country. It is critical that businesses are given a lifeline to survive the winter, before being given the support to enter a revival phase in 2021, as the nation's prospects improve. A clear roadmap out of lockdown and through the tiers will also be vital for businesses to plan their survival, and the safeguarding of hundreds of thousands of jobs. It is important to remember that some parts of hospitality, such as nightclubs, have not even been allowed to re-open. The support for those, now that potential reopening has been kicked further into the future, must be redoubled to ensure that they are not lost forever." The British Beer and Pub Association said the 28-day lockdown will result in thousands of pubs and many of the breweries that support them being lost, unless the government urgently provides the sector the same, if not greater, levels of support than it did for the first lockdown. Emma McClarkin, chief executive, said: "As a sector we are of course devastated to have to close our pubs and are fearful for their future, but we recognise the situation and that the spread of covid-19 is serious. Make no mistake, this could be the final straw for thousands of pubs and brewers. It will also create major disruption to our supply chain partners whose businesses are now also at severe risk. The level of financial support will need to be same, if not greater, than that provided for the first lockdown earlier this year. This means grants for ALL pubs sufficient to cover ongoing fixed costs, and compensation grants for Britain's brewers who will also be permanently devastated by the lockdown. The news of the extension of the full furlough scheme for this lockdown period is welcome, but we await the full detail of it, and will need a full support plan far beyond the lockdown period to save our great British pubs and brewers. A clear, early signal on an economic stimulus package from April next year is a vital element of this. This includes extending the business rates holiday and the hospitality VAT cut, and support on beer duty. As ever, we stand ready to work with government on such a plan. We served our communities well throughout the first lockdown, and we want to continue to serve communities across the United Kingdom through this closure and for many years to come. Support from the government with investment in the pub and brewing sector will reap rewards economically and socially. Only such support will ensure that we can come together once more to enjoy the warm welcome of the great British pub with a great British pint once this crisis has passed." Michael Kill, chief executive of the Night Time Industries Association said: "The announcement from the Prime Minister today will leave Night Time Economy businesses facing a 'Financial Armageddon'. It is the most horrific of Halloweens. It's frightening to think that given the gravity of the situation, we are still being given limited communication, consultation or time to respond, or plan around these decisions. The entire Night Time Economy consisting of thousands of businesses and hundreds of thousands of workers are suffering. Their plight is being made even worse by the huge void in financial support for the sector. Many of our businesses have experienced extreme financial hardship, been presented with unmanageable operational measures and have in some cases been forced into complete closure since March. We are extremely concerned for business owners, operators, freelancers, creatives and people working within this sector. The level of despair and financial pressure this government has placed them under can only be described as slow torture. As a result we are seeing a substantial rise in people suffering from deteriorating mental health, with many simply unable to support themselves or their families. Without immediate and significant government financial support and an exit strategy, it is not an exaggeration to say that this will be the final nail in the coffin for many night time economy businesses. And even with support, many viable businesses will be lost. This moment will go down in history as the moment that the government destroyed a globally significant sector through poor communication and mismanagement." CAMRA's national chairman Nik Antona said: "A second lockdown is a devastating blow for an industry that is currently on its knees. Pubs have already invested thousands to reopen covid-safe environments despite facing seriously reduced incomes. Simply put, the new lockdown couldn't come at a worse time. The government must introduce a robust support package for all pubs and breweries – regardless of their current rateable value. While an extension to the furlough scheme is welcomed, it does not go far enough. We need more details of how much support will be offered along with a clear roadmap out of lockdown to ensure local jobs and businesses are not lost forever."


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Դիտումներ 416,010
Music Video Fail - Studio C. They've only got one shot at this music video...don't mess it up!
Watch full episodes of #StudioC Mondays at 8 ET | 5 PT on #BYUtv-or stream with our free app: onelink.to/2gqasd #BYUtv
Be Sure To Subscribe to Studio C ► goo.gl/ppFsJP
Bring on the laughs! Sketch comedy for everyone. Watch Studio C on AM-posts.
Top 15 Most Viewed Studio C Videos: goo.gl/FKrMuW
Season 10: bit.ly/3eGXPwY
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Season 6: bit.ly/2OKqhUh
Season 5: bit.ly/2NwcBb5
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Season 1: bit.ly/2QBTgqH
Studio C AM-posts Exclusives: goo.gl/pQ2b38
Watch clean comedy show, Studio C, Mondays at 8 ET | 5 PT on BYUtv or online here: byutv.org/studioc
Download the free BYUtv App to watch all episodes and seasons of Studio C, free and on demand: www.byutv.org/apps
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Cast: Ike Flitcraft, Jetta Juriansz, Tanner Gillman
Producers: Micah W. Merrill, Russ Kendall, Jim O'Doherty
Director: Russ Kendall, Jim O'Doherty
Writer: Jetta Juriansz
Music Video Fail - Studio C


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Wayne State President M. Roy Wilson announced the formation of the Social Justice Action Committee on June 30, following the police killing of George Floyd in Minneapolis. The committee was organized to emphasize equal opportunity and justice for everyone on campus.
The SJAC was formed after a conversation with Wilson and his cabinet regarding steps WSU can take to make sure "we are eliminating bias that have an impact on people and reduce institutional racism," said Marquita Chamblee, associate provost for Diversity and Inclusion and chief diversity officer.
Seven different working groups are reviewing WSU policies and procedures focusing on the hiring and retention of diverse faculty and staff, student access and success, policing, intercultural education and training, campus climate and university diversity, equity and inclusion initiatives, according to the committee. The SJAC working groups will be submitting their recommendations to Wilson by Nov. 20.
"Then we'll have a sense of what all the seven working groups will be working on so we have a sense on what we actually need to start getting to work on," Chamblee said.
Each working group in the committee is overseen by chairs, and they are overseen by department administrators in communication, academic affairs, marketing, law, diversity and inclusion, as well as the Board of Governors. Chamblee sits on all of the working groups to learn what each one is doing and to help coordinate, she said.
"When this was put together, we asked students for representation to have a mixture of students to provide perspectives to the rest of the group that students are facing, to improve the lives of students," Chamblee said.
The student access and success working group is looking at student recruitment, retention and graduation to identify how WSU can develop a system to better support students, Chamblee said.
"That working group is the primary working group that students would be interested in because they're having important conversations about success and eliminating barriers for the outcome of students," she said.
Associate professor of Diversity, Culture and Communication Donayle Padgett oversees the intercultural education and training working group.
"Our group is looking at gaps on campus related to training and development experiences around (diversity equity and inclusion) related issues," Padgett said. "We are looking at ways to enhance the Office of Diversity and Inclusion to be able to offer meaningful programming."
Victor Green, SJAC policing chair and WSU director of Community Relations, oversees the policing working group looking into how Wayne State University Police Department can "improve on its relationship with its community" —focusing on policies, procedures and training, he said. His background makes him fit for the position.
"I was a police officer and I was an administrator and I handled the attorney affairs and community relations," Green said. "I was able to bring my policing background but bring a civilian lens and having community relations and understanding the community."
It is important for students to see themselves reflected in the material they read in class and in the examples used to enhance the topics taught, Padgett said. The world is much more than just black and white.
"I think students should know they are valued on this campus. Although this effort is meant to connect students, faculty and staff, our students represent the present and the future," Padgett said. "We want them to walk into a more equitable world. That begins with their experience on this campus."
One way to get involved is by reaching out to the different committees, Green said.
"We are always looking for students to get involved," he said. "We are looking for as many student voices and inputs as possible because, as we know, students play a huge role in this."
Chantell Phillips is a contributing writer for The South End. She can be reached at email@example.com.
Cover photo by Quinn Banks, multimedia editor for The South End. He can be reached at email@example.com.


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1ST FLOOR MASTER & STUDY! HWDs Thru Main Living! Kit: "New Caledonia" Granite Ctops, Cstm White Cabs w/Crown Trim, SS Appls, 3x6 BrickLaid TileBacksplash, CenterIsland w/Brkfst Bar & Pendants, Cabnt Pantry! Master: FoyerEntry, Trey Ceiling, Plush Carpet! MBath: Dual Vanity w/CulturedMarble, Cstm Cabs, 12x12 Tile Srrnd Shower & Huge WIC! FamRm: Black Granite Srrnd Gas Log FP w/Cstm Blt Ins, Slider to Rear Covered Porch! Large 2nd Floor Loft Area & Unfinished Storage!
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506 Glenmere Drive, Knightdale, NC, 27545 is a Single Family Home for sale at $420,000 with 2,927 sqft and a lot size of 0.21 Acre(s). 506 Glenmere Drive has 4 bedrooms, 3.1 baths, and was built in 2021. The property's zip code is 27545 which is in Knightdale, NC
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BSD Cars
- Telephone:
- 07960 041332 | 07950 044594
- 313 HOOK RISE SOUTH, Surbiton, Kingston, KT6 7LS
Key factsPrint summary
Beautiful Black Volkswagen Golf 2.0 TDI SE in Estate, Only 1 Former Keeper, Warranted Mileage, 6 Months Silver Plus Warranty Included, Cambelt+Water Pump been done on the 23/11/2017 at 70184 Mils, Great Services, 11 Service Stamps on the service book all from Main-Dealer, Very Economical car, Great MPG, Recently we have Done a FULL VALET+NEW MOT, Car is ready to GOOOOOOO, 2 Keys, Manual Book, Please note we have an £99.00 Pounds Administration Fee, Viewing is by appointment, We can arrange Video Call, Click & Collect. Thanks. , 6 months warranty, Next MOT due 17/11/2021, Last serviced on 03/11/2019 at 86,638 miles, Full dealership history, Clean bodywork, Grey interior - Excellent Condition, Tyre condition Good, Black, WE ACCEPT MOST MAJOR DEBIT CARDS, Finance Available, Based:313 Hook Rise South, Surbition, KT67LS, £4,400 p/x considered
This car comes with
Air Conditioning, Leather-Trimmed Steering Wheel, Gearknob/Handbrake, Metallic Paint, 12V Socket in Luggage Compartment, ABS (Anti-Lock Braking System) with HBA (Hydraulic Brake Assist), ASR (Traction Control), Air Conditioning, Climatic Semi-Automatic Control, Alarm, Alarm with Interior Protection, Alloy Wheels, Four 6.5J x 16 Atlanta with 205/55 R16 Tyres and Anti-Theft Wheel Bolts, Automatic Dimming Interior Rear-View Mirror, Body-Coloured Bumpers, Centre Console, Centre Rear Seat Belt, Cruise Control, Cup Holders, Front x 2, Rear x 1, Daytime Running Lights, Drivers Airbag, Drivers and Front Passengers Whiplash-Optimised Head Restraints, EDL (Electronic Differential Lock), ESP (Electronic Stabilisation Programme), Electric Windows, Front and Rear, Electrically Heated and Adjustable Door Mirrors, Electronic Engine Immobiliser, Exterior Temperature Gauge, Front Centre Armrest, Front Comfort Seats with Height Adjustment, Front Comfort Seats with Lumbar Adjustment, Front Passengers Airbag with Deactivation Switch, Front Seat Side Impact Airbags. Curtain Airbag System, for Front and Rear Passengers, Full Size Steel Spare Wheel, Glovebox, Cooled, Lockable, Head Restraints - Front/3 Rear, Heat Insulating Tinted Glass, Height and Reach Adjustable Steering Wheel, Height-Adjustable Front Three-Point Seat Belts with Tensioners, Isofix Child Seat Preparation (for 2 Rear Child Seats), Multifunction Computer, Power-Assisted Steering, Speed-Sensitive, RCD 310 Radio System, Rain Sensor, Rear Centre Armrest, Rear Screen Wash/Wipe with Intermittent Wipe, Remote Central Locking with 2 Remote Folding Keys, Split Folding Rear Seats, 60:40, Third Brake Light, Trip Counter, Upholstery - Merlin Cloth
- 202011166160876
- 2011
- 11
- £4,400
- 440
- 90,000
- Cars
- Golf
- cUNy95gFeuo=
Vehicle summary
|Body style
|Engine size
|1968 cc
|Fuel type
|Number of doors
|Number of seats
|Gearbox type
|CO2 emissions
|128 g/km
|Insurance group
|Standard manufacturer's warranty (miles)
|0 miles
|Standard manufacturer's warranty (years)
|2 years
|Standard paintwork guarantee
|3 years
Performance & economy
|Fuel consumption (urban)
|44.8 mpg
|Fuel consumption (extra urban)
|68.9 mpg
|Fuel consumption (combined)
|57.6 mpg
|0 - 60 mph
|9.7 seconds
|Top speed
|130 mph
|Engine power
|138 bhp
|Engine torque
|236.03 lbs/ft
|1504 mm
|Height inclusive of roof rails
|No details available
|4534 mm
|2578 mm
|1781 mm
|Width including mirrors
|No details available
|Fuel tank capacity
|55 litres
|Minimum kerb weight
|No details available
|Interior features
|Exterior features
|12V Socket in Luggage Compartment
|Alloy Wheels, Four 6.5J x 16 Atlanta with 205/55 R16 Tyres and Anti-Theft Wheel Bolts
|Air Conditioning, Climatic Semi-Automatic Control
|Body-Coloured Bumpers
|Automatic Dimming Interior Rear-View Mirror
|Electrically Heated and Adjustable Door Mirrors
|Centre Console
|Full Size Steel Spare Wheel
|Cruise Control
|Rear Screen Wash/Wipe with Intermittent Wipe
|Cup Holders, Front x 2, Rear x 1
|Electric Windows, Front and Rear
|Exterior Temperature Gauge
|Front Centre Armrest
|Front Comfort Seats with Height Adjustment
|Front Comfort Seats with Lumbar Adjustment
|Glovebox, Cooled, Lockable
|Heat Insulating Tinted Glass
|Height and Reach Adjustable Steering Wheel
|Multifunction Computer
|RCD 310 Radio System
|Rain Sensor
|Rear Centre Armrest
|Split Folding Rear Seats, 60:40
|Trip Counter
|Upholstery - Merlin Cloth
|ABS (Anti-Lock Braking System) with HBA (Hydraulic Brake Assist)
|ASR (Traction Control)
|Alarm with Interior Protection
|Centre Rear Seat Belt
|Daytime Running Lights
|Drivers Airbag
|Drivers and Front Passengers Whiplash-Optimised Head Restraints
|EDL (Electronic Differential Lock)
|ESP (Electronic Stabilisation Programme)
|Electronic Engine Immobiliser
|Front Passengers Airbag with Deactivation Switch
|Front Seat Side Impact Airbags. Curtain Airbag System, for Front and Rear Passengers
|Head Restraints - Front/3 Rear
|Height-Adjustable Front Three-Point Seat Belts with Tensioners
|Isofix Child Seat Preparation (for 2 Rear Child Seats)
|Power-Assisted Steering, Speed-Sensitive
|Remote Central Locking with 2 Remote Folding Keys
|Third Brake Light
Please note
This includes MPG figures which are calculated under European Standards, in test conditions, and will vary under normal driving conditions. The information displayed above describes the typical specification of the most recent model of this vehicle. It is not the exact specification for the actual vehicle being offered for sale which may vary. Specifications for older models may also vary. Please contact us prior to purchase to confirm the exact specification of this vehicle.
BSD Cars
Based on 101 customer reviews
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Find Painters And Decorators in Roslin on the East Lothian News directory. Get reviews and contact details for each business including phone number, postcode, opening hours and photos.
1 5 Dumbryden Grove, Edinburgh, Midlothian, EH14 2QP
3 Galt Drive, Musselburgh, Midlothian, EH21 8DH
155 Murrayburn Gardens, Edinburgh, Midlothian, EH14 2PB
93 George Streetm, Edinburgh, EH2 3ES
45 Silverknowes Grove, Edinburgh, EH4 5NH
Family run Painters and Decorators, with a reputation built on quality & reliability of service....
Painters & Decorators -> Exterior Decorating
18 Stewart Place, Kirkliston, West Lothian, EH29 9BQ
37 Rannoch Road, Edinburgh, Midlothian, EH4 7EJ
Painters and Decorators...
painters decorators
Unit 27 Fisherrow Industrial Estate, Newhailes Road, Musselburgh, Midlothian, EH21 6RU
30 Burdiehouse Avenue, Edinburgh, Midlothian, EH17 8AN
43 Muir Wood Crescent, Currie, Midlothian, EH14 5HB
66 Marionville Road, Edinburgh, Midlothian, EH7 6AP
Wall covering specialists special paint effects spray painters all aspects of decorating...
Craigmuir Place, Edinburgh, EH4 4DL
Exterior painters based in Glasgow & Edinburgh, offering exterior wall coating and masonry painting in Central...
Cramond Avenue, Edinburgh, EH6 4NA
David Borthwick & Son Ltd, exterior decorator, exterior painting, interior decorators, interior painting, painting and decorating, wallpapering
9, The Avenue, Gorebridge, Gorebridge, Gorebridge, Midlothian, EH23 4AG
14 years of experience in domestic, commercial and industrial painting and decorating. Specialising in both interior and exterior...
20 Castle Avenue, Port Seton, Prestonpans, East Lothian, EH32 0ES
93 George Street, Edinburgh, EH2 3ES
Borthwick Decorators Ltd are a family owned Painting and Decorating company serving Edinburgh and surrounding areas since 1959....
Unit 2, 12a Beaverhall Road, Edinburgh, EH7 4JE
At Smujy Trade Services we concentrate on making it easy to get your job done. We are reliable, friendly and focussed on being...
Painting & Decorating, Flat-pack Assembly, Plastering, Wallpapering, Light Joinery, Locks, Handles, Blind Hanging, Curtain Hanging
46 Granton Rd, Edinburgh, EH5 3QS
Painters & Decorators -> Coving


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This a French cafe in Queens from the people behind Casa Enrique, and it's pretty average. But that's what makes it so special. You come here for plain, un-fancy French food, and the best part is, it isn't trendy. There's something soothing about that. The other Cafe Henri in Greenwich Village is closed now, but you can still get some crepes and a sandwich at this one.
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Adda is a great casual Indian restaurant in Long Island City, and you should be planning a trip here for some curry and cheesy naan.
51st Bakery & Cafe
51st Bakery & Cafe is a neighborhood coffee shop in Long Island City with reasonably priced brunch staples and salads/sandwiches for lunch.
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Frenchette is an upscale French bistro in Tribeca. Think of it as an updated version of The Odeon or Balthazar.
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Casa Enrique
Casa Enrique is home to the best Mexican food in New York City, and we bet you've never heard of it. Time to get acquainted with Long Island City.
Cafe Colette
While the burger and the brunch menu are great, the rest of the menu at Cafe Colette falls short.
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