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New to the CAZy classification? Read this first.
Want to learn more about CAZypedia? Read the CAZypedia 10th anniversary article in Glycobiology.
Glycoside Hydrolase Family 16
Responsible Curator as essentially complete. CAZypedia is a living document, so further improvement of this page is still possible. If you would like to suggest an addition or correction, please contact the page's Responsible Curator directly by e-mail.
|Glycoside Hydrolase Family 16
|Active site residues
|CAZy DB link
Substrate specificities
The members of family 16 are active on β-1,4 or β-1,3 glycosidic bonds in various glucans and galactans. A wide diversity of glycoside hydrolases active on plant and marine polysaccharides are found in GH16, including:
- keratan-sulfate endo-1,4-β-galactosidases (EC 220.127.116.11),
- endo-1,3-β-galactanases (EC 3.2.1.-),
- endo-1,3-β-glucanases (EC 220.127.116.11),
- endo-1,3(4)-β-glucanases (EC 126.96.36.199),
- licheninases (EC 22.214.171.124),
- β-agarases (EC 126.96.36.199),
- β-porphyranases (EC 126.96.36.199) [1],
- κ-carrageenases (EC 188.8.131.52), and
- endo-xyloglucanases (EC 22.214.171.124, a.k.a. xyloglucan endo-hydrolases, XEHs, in plants [2]).
Notably, some members of GH16 are predominant transglycosylases. These include the plant xyloglucan:xyloglucosyltransferases (EC 220.127.116.11, a.k.a. xyloglucan endo-transglycosylases, XETs) [2] and yeast chitin/beta-glucan crosslinking enzymes Crh1 and Crh2 [3, 4, 5]. Some invertebrate GH16 proteins have lost their catalytic amino acids and are involved in immune response activation through the Toll pathway upon binding of β-1,3 glucan. The role of the GH16 domain in this immune response has not been fully elucidated [6].
Several of the activities observed for GH16 members are delineated into individual sequence-based subfamilies, while other polyspecific subfamilies capture a range of activities [7].
Kinetics and Mechanism
Members of GH16 enzymes are retaining enzymes, as first shown by NMR [8] on an endo-1,3-1,4-β-D-glucan 4-glucanohydrolase from Bacillus licheniformis. As such, they utilize a covalent glycosyl-enzyme intermediate, which is broken-down by glycosyl transfer [9, 10] to water or a carbohydrate acceptor substrate in glycoside hydrolases or transglycosylases, respectively.
Catalytic Residues
The catalytic nucleophile of GH16 enzymes was first proposed using a non-specific epoxyalkyl β-glycoside inhibitor and identification of the site of covalent labelling using ESI-MS and Edman degradation on an endo-1,3-1,4-β-D-glucan 4-glucanohydrolase from Bacillus amyloliquefaciens [11]. This was subsequently verified by azide rescue of the E134A mutant of a Bacillus licheniformis 1,3-1,4-β-D-glucan 4-glucanohydrolase resulting in an α-glycosyl azide from the β-glycoside substrate [12]. The general acid/base residue was identified by making the E138A site-directed mutant of the Bacillus licheniformis 1,3-1,4-β-D-glucan 4-glucanohydrolase together with kinetic analysis and azide rescue, which resulted in a β-glycosyl azide product [12]. These structurally conserved catalytic residues have been confirmed in a number of other GH16 members, including plant XETs and XEHs [13, 14], and yeast Crh1 and Crh2 [5].
The mechanistic analysis of bacterial mixed-linkage endo-glucanases has been expertly reviewed in the broader context of GH16 [15].
Three-dimensional structures
Proteins in GH16 share a β-jelly-roll fold in which two β-sheets align in a curved, sandwich-like manner and present a cleft-shaped active-site bounded by loops extending from the β-strands. The first solved 3D structure was a hybrid protein of licheninase M from Paenibacillus macerans and BglA from Bacillus amyloliquefaciens (PDB 1byh) in 1992 [16]. Many three-dimensional structures have been solved of family 16 members of archeal, bacterial, and eukaryotic origin (see http://www.cazy.org/GH16_structure.html for an updated list). Of these, the first eukaryotic 3D structure was the xyloglucan endo-transglycosylase PttXET16-34 from Populus tremula×tremuloides (PDB 1umz) [17] and the first archeal 3D structure was a endo-1,3-β-glucanase Lam16 from Pyrococcus furiosus (PDB 2vy0) [18].
The structural diversity of GH16 members across sequence-related subfamilies has been reviewed in detail [7].
Evolution of GH16
GH16 is a member of clan GH-B together with GH7; both families share the β-jellyroll fold. The different specificities of GH16 are proposed to have evolved from an ancestral β-1,3-glucanase [19]. This proposal was first elaborated using a structure-based phylogeny approach, which suggested that an early branching event lead to the evolution of the bacterial κ-carrageenases and the β-agarases, while a later branching event lead to the bacterial licheninases and the plant XETs [20] (Figure 1). GH16 has more recently been divided into subfamilies within CAZy, the corresponding phylogenetic analysis of which supports this overall evolutionary trajectory [7].
Particularly notable, the GH16 active-site residues are located in-train on one beta-strand at the center of the substrate binding cleft. Depending upon the phylogenetic clade, this beta-strand features one of two topologies. The beta-bulge motif, which has the consensus sequence EXDXXE, is more frequent in GH16 compared to the regular beta-strand with the consensus sequence EXDXE (the catalytic nucleophile is the first glutamate and the catalytic acid/base is the second, with a proposed "helper" asparate in-between [15]). Due to the predominance of the beta-bulge motif and its presence as the only motif in GH7, Michel et al. proposed that the beta-bulge is the ancestral motif, which subsequently gave rise to the regular beta-strand of extant plant XETs and bacterial licheninases [20].
Within plant lineages, similar structure-based phylogenetic approaches have suggested that XEHs evolved subsequently to XEHs within the xyloglucan endo-transglycosylase/hydrolase (XTH) gene family [2, 21]. The identification of a group of bifunctional GH16 glycoside hydrolases, which is active on both mixed-linkage beta-glucan and xyloglucan, provides additional support for the close evolutionary relationship of XETs and licheninases [22, 23, 24].
Family firsts
- First stereochemistry determination
- Bacillus licheniformis 1,3-1,4-β-D-glucan 4-glucanohydrolase by NMR [8].
- First catalytic nucleophile identification
- Suggested in Bacillus amyloliquefaciens 1,3-1,4-β-D-glucan 4-glucanohydrolase via non-specific epoxyalkyl β-glycoside labeling [11]. Later verified by azide rescue of inactivated mutants [12].
- First general acid/base residue identification
- Bacillus licheniformis 1,3-1,4-β-D-glucan 4-glucanohydrolase, first suggested by sequence homology and mutational studies [25]. This was later verified by azide rescue of inactivated mutants [12].
- First 3-D structure
- A hybrid licheninase (Bacillus amyloliquefaciens and Paenibacillus macerans) by X-ray crystallography (PDB 1byh) [16].
Reference list
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- Hehemann JH, Correc G, Barbeyron T, Helbert W, Czjzek M, and Michel G. (2010) Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota. Nature. 464, 908-12. DOI:10.1038/nature08937 |
- Eklöf JM and Brumer H. (2010) The XTH gene family: an update on enzyme structure, function, and phylogeny in xyloglucan remodeling. Plant Physiol. 153, 456-66. DOI:10.1104/pp.110.156844 |
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- Sinnott, M.L. (1990) Catalytic mechanisms of enzymic glycosyl transfer. Chem. Rev. 90, 1171-1202. DOI: 10.1021/cr00105a006
- Bissaro B, Monsan P, Fauré R, and O'Donohue MJ. (2015) Glycosynthesis in a waterworld: new insight into the molecular basis of transglycosylation in retaining glycoside hydrolases. Biochem J. 467, 17-35. DOI:10.1042/BJ20141412 |
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10.24 acres near Ithaca bordering Treman State Park in the Finger Lakes Region of New York. This quality land parcel is in a unique setting on Thomas Road in the Newfield School District Town of Enfield. The level 10+ acres is bordered on 3 sides by the Robert Treman State Park ready for your new house. It's a beautiful setting with open field in the front and woodland in the back so you can walk into the State Park and reach the Finger Lakes Trail where you can hike for hundreds of miles. Archery hunting is allowed in the Park by permit only. The land is located in an agricultural district which would allow you to do some farming and raise livestock if that's in your future plans. Great location only minutes from Wegmans, Lowes, Home Depot and the Ithaca Commons. There is another 10+ acres also available adjoining this parcel. Both lots are being offered at $118,900 each.
Listing information provided courtesy of the Ithaca Board of REALTORS. IDX information is provided exclusively for consumers' personal, non-commercial use and it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The data is deemed reliable but is not guaranteed accurate by the MLS. This information has been obtained from sources believed to be reliable, but no representations or warranties expressed or implied, as to the accuracy of the information are being made by Ithaca Board of REALTORS or the owner/publisher of this website. Anyone using this information without independently verifying its accuracy bears all risk for any inaccuracies. Updated: 30th November, 2020 3:59 AM
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The Lazy Dog Cookie Co. Happy Birthday Pup-PIE Dog Treat, Girl
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Celebrate your dog's special day with a tasty slice of the The Lazy Dog Cookie Co. Happy Birthday Pup-PIE Dog Treat. Created because every dog deserves a piece of pie, this unique treat is made with simple ingredients that are amazingly delicious and naturally nutritious. And because the compassion for all animals run deep at The Lazy Dog Cookie Co., all of their products are vegetarian and vegan. When it comes right down to it, they're just plain good, wholesome treats that you can feel good about giving your dog—and your dog will feel even better about being on the receiving end of them.Key Benefits
- Made in the USA with no dairy, soy, wheat, corn, or GMOs with wholesome ingredients.
- Made with simple ingredients that are amazingly delicious and naturally nutritious.
- Pie-inspired dog treats comes with ten slices of tasty goodness to celebrate your dog's birthday.
- Topped with a dairy-free coating and sprinkled with multi-colored sesame seeds.
- Vegetarian and vegan recipe is handmade and hand-sliced with a soft-baked texture.
Shop Our Entire Birthday Assortment!
Item Number120633
Dimensions6 x 6 x 1 inches
Weight5 ounces
Breed SizeSmall Breeds, Medium Breeds, Large Breeds, All Breeds
Food FormTreats
Special DietN/A
Oat Flour, Cane Molasses, Pumpkin, Peanut Butter (Ground Peanuts), Coating (Cane Sugar, Palm Oil, Vanilla & Sunflower Lecithin), Sesame Seeds, Cinnamon, Ginger, Sodium Bicarbonate & Color Added. (*All ingredients are Non-GMO)Caloric Content
48 kcal/0.5 oz slice
|Guaranteed Analysis
|Crude Protein
|7.84% min
|Crude Fat
|8.28% min
|Crude Fiber
|2.54% max
|14.77% max
Intended for intermittent or supplemental feeding only.
Customer Reviews
87% Recommend
87% of reviewersrecommend this product
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235 Reviews
Showing 1-10 of 235 Reviews
a little disappointed
By tjg2007 on Nov 28, 2020
i thought this item was super cute and perfect for my dogs birthday. When we got it, the treat was super hard. I tried breaking pieces off with my hand and couldnt, i had to use a large kitchen knife to break off pieces but was too hard for her to eat and ultimately i decided not to give her any more than one piece that i watered down to soften up. Wish it was somehow made differently so it was easily edible for my dog.
They loved it.
By Nanci on Nov 9, 2020
This was a wonderful treat for my Idgie's birthday. I have a total of five dogs and they all got some. This is an appetizing, quality treat. It looks good and smells good. I tasted it and it was good to me. I tried to save half for later, (again) but they saw where I put it and I kept getting the "why can't we have that Mom?" looks, and I gave in to the pressure. This is the second one of these I've bought, and I will buy again.
Birthday pup LOVED it!!
By AllyCat on Oct 12, 2020
My pup turned 9 years old today and I gave her this to celebrate the occasion! She's really picky when it comes to treats, so I was very surprised when she ate almost the entire thing! I did have to warm it up in the microwave with a damp paper towel to soften it up a little bit, but it was still a hit! The cake itself has a heavenly scent of gingerbread. I'll definitely be getting this again!!
Both dogs sick
By Chey on Oct 20, 2020
I ordered this as a special birthday treat for our Staffie to share with our other dog as well. I cut it on the lines and only gave them 2 small slices each, both dogs weigh 60+ pounds. I gave it to them last night 10-19 and by this morning, 10-20, our staffie has thrown up twice and our hound has thrown up 3 times. Nothing makes these dogs sick, and the fact they are both puking all over the house makes me never want to buy this product again
Looked awesome but the animals wouldn't eat it
By AnimalLover on Oct 30, 2020
This looked wonderful, it even smelled good, but none of the animals would eat it. My daughter even tried it and she said it was "gross tasting" LOL she is a believer that if the animals eat it than she should try it too. We tried to feed it to them a couple of different times and ended up just tossing it.
Barbie Q Riblet
By Brenda on Oct 17, 2020
I got this for my mini pig's birthday. Being a vegetarian treat is why I got this for her. It smells good enough to eat yourself! It smelled like gingerbread. When Barbie got a whiff she got sooo excited! She was one extremely happy piggy!
Ended up tossing......
By Pekemom on Sep 9, 2020
Cute but my 1 yr old Peke puppy and her 13 yr old brother, didn't go for it. I made her a homemade doggie cake and she MUCH PREFERRED that then this! Funny, b/c my dec. Peke ABSOLUTELY went CRAZY over this. I gave it 2 stars b/c it's cute and the wrapping says it all. The pie is TINY ! BEWARE!!!! I would NEVER get another! It's not worth it for the cost. You can make Several homemade ones for the price of this.......!!!! BEWARE!!! I strongly suggest that.........!!! And they are probably more nutritious then this is.
Hard as a rock
By TSMom on Oct 26, 2020
When I opened the package there were ALOT of crumbs. But when I went to cut it I couldn't. Both dogs walked away from it. Threw it out. No birthday cake for my pups. Got a blue one for my boy and threw it away imm. It had bugs in it.
They loved it!
By BexL on Dec 2, 2020
Bought this to celebrate my puppy turning 4, she shared with her 6 friends and all 7 dogs loved it, plan on purchasing again for the next dog in the family birthday.
Birthday girl loved it
By SheltiLover on Nov 14, 2020
We have 4 Shelties, the youngest just turned #1! Of course they absolutely loved the Pup-pie and devoured it!! As the human, I thought it was really hard, but hey what do I know!!


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A Snack KM2531 – Royal Doultoun Storybook Figurine
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Interactive Documentation. All action on our reverse phone number lookup is totally confidential. You will receive an email with a link to download your report, after processing is complete. All you need do is enter phone book number (e.g. 123-456-7890) that is, the phone number that you would like to look up into Google's search bar to determine their find phone number owner outcomes. Whitepages has the largest database of contact info of Americans. Make a note of the unknown amount.
The RxRD accounting staff will follow-up with ALL of them until you receive the complete the credit potential for returned goods. There are numerous great services available — that are very cheap — but before we list these, here is some additional information that will help you understand each service. Once signed up, you'll have the ability to test out the API's features as you go through their Documentation. Whether you decide to tell the owner of the amount how you identified them or not is your decision.
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Meet the 2013 anti-gay Bigots of the Year
American author Oliver Wendell Holmes once said: 'The mind of a bigot is like the pupil of the eye; the more light you pour upon it, the more it will contract.'
For as much progress countries and communities are making with regards to marriage equality, homophobic bullying and transgender discrimination, the fight is far from over.
With the rapid-fire speed of social media, it seems someone, somewhere, is always making harmful comments to and about the LGBTI community.
All we need to look at is the hateful messages Tom Daley recieved after coming out earlier this year.
This year we saw politicians, Harvard professors and even the CEO of a pasta company make global headlines for making their homophobic feelings public.
Many justify their anti-gay comments with political and religious ideals, but there's still no acceptable reason to say and do what some of the following people put out into the world this year.
1. Pat Robertson, TV Evangelist wants Facebook 'vomit' button for LGBTI posts
There was no way TV evangelist Robertson wasn't going to make it to our list. His conservative Christian ideals and anti-gay views won him gay rights group Stonewall's 2013 Bigot of the Year.
Robertson has compared transgender people to his castrated horse and said gays are just straight people who have 'forsaken God'.
He has also expressed his desire for a 'vomit' button on Facebook so he could show how much he dislikes LGBTI-related posts.
2. Scott Lively, conservative Christian leader and supporter of Uganda's Anti-Gays Bill
The outspoken Massachusetts-based Christian leader is well-known for being an inspiration for Russia's anti-gay laws. His views were spread and followed by a series of prohibitions on gay propaganda in Russian.
Previously he admitted to supporting the criminalization of homosexuality in Uganda and the country's 'Kill The Gays' bill. He is now facing trial in the United States for crimes against humanity.
He also toured Latvia with a translator wearing a 'No Pride' shirt and told Latvian police officers: 'The gay movement is the most dangerous political movement on earth.' He publicly said he is proud of all he did.
3. George Gabauer, UK vicar who refused to baptize lesbian couple's baby
The Church of England vicar refused to christen a baby boy after both his lesbian parents wanted to register as his mothers.
Instead he wanted one of them to register as a godmother, saying it is illegal for a baby to have two mothers. He also said he 'feels sorry' for gay people because they are 'medically imbalanced'.
4. Winston McKenzie, UKIP candidate against gay adoption
Gay rights organization Stonewall called the UK Independence Party candidate for Croydon North a 'political obsessive' after his comments on gay adoption.
McKenzie said it's 'not healthy' for children to be adopted by a gay couple and compared it to throwing 'children to dogs.'
5. Niall Ferguson, Harvard professor
Early this year Harvard professor Ferguson implied the late British economist John Maynard Keynes did not care about future generations because he was gay and childless. He said Keynes economic views were influenced by his homosexuality.
Ferguson apologized for his comments and said he didn't mean any harm. However, this was not the first time Ferguson criticized Keynes based on his homosexuality, and students said Ferguson mentioned Keynes's sexuality during his lectures back in the 90s.
6. Guido Barilla, head of Barrilla Pasta
Earlier this year, Barilla Pasta's chairman said he would not use gay people in his adverts.
Guido Barilla said the concept of the 'classic' family was fundamental and if the LGBTI community didn't like the concept they could buy pasta from a different brand.
He said he didn't disrespect gay people but however, they don't think the same way. Barilla later apologized for his comments but it was already too later as millions of Italians campaigned to boycott the brand.
Check out Barilla's apology speech:
7. Homophobic subway preacher
A preacher in a New York City subway car referred to gay people as an 'abomination' and 'sick'.
People ignored the bigot and waited for him to go away but one gay passenger stood up and said: 'I'm a good man! And I'm a gay man and Jesus loves me!'
Check out the video below:
8. US Senator Marco Rubio
Marco Rubio, a potential 2016 Republican presidential candidate, said earlier this year being anti-gay doesn't make him a bigot.
However, according to OnTheIssues.org: He is against gay parents being fosters parents; is opposed to the Employment Non-Discrimination Act (ENDA); supports a federal amendment to prevent same-sex marriage; and supports banning homosexuals in the military.


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2016 Jeep Renegade Latitude SUV 2.4L 4 CYL
Contact us:
Ontario, CA 91762
(909) 225-7528
Send a Note / ShareTweet
SOLD BY CARCO, We are Located @ 201 S Laurel Av Ontario CA 91762, To schedule test drive please call, 9o9 22FIVE-7FIVE-28, or, write to us at, email@example.com, Thank You, This vehicle Comes with Clean title Like New Condition Runs and drives Great Everything works on it, Good Tags Smogged and ready to Go! Warranty Available! Financing Available! Work hours 10am-7pm Mon-Sun
About this 2016 Jeep Renegade - $12,995
Exterior Color: White
Interior Color: Black
Doors: 4 Door
Stock: 36891
Stereo: Premium Sound System
Mileage: 50,000
Engine: 2.4L L4 DOHC 16V
Bodystyle: Sport Utility
Transmission: Automatic
Drivetrain: FWD
Vin: ZACCJABT9GPE36891
- Child Safety Door Locks
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*Prices do not include government fees and taxes, any finance charges, any dealer preparation charges and any emission testing charge. Due to our ever changing inventory, this vehicle shown may not be available at this time, so please call for availability. Also due to test drives that occur at the dealership, miles shown are approximate.


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Savka Todorovska: Vote for the option of a better life
- 512 Views
- 08/12/15
- in Newsroom
- Comments Off on Savka Todorovska: Vote for the option of a better life
Activist Savka Todorovska for the voting of women for a better future:[youtube width="600″ height="400″]https://www.youtube.com/watch?v=BxyL8tFPv_o[/youtube]
Women have never had the right to choose or to be chosen. Therefore, dearly respected, use the right now, go out freely to vote at democratic and fair elections. Vote according to your own choice, for a better future for women, that is, better future for the citizens. The option that provides free elections and a better life, that's democracy.
Follow the campaign For Free Elections also on:
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New Balance Men's 1300
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Breaking news: It's not easy to stop Steph Curry from scoring the basketball.B Crazy, right? Is he the toughest cover for Jamal Murray? The answer is "yes," and the Denver Nuggets star guard recently explained why to Ashley Nevel during a conversation posted to YouTube.
November 25, 2020 | 2:00 pm EST Update
Josh Lewenberg: Marc Gasol on choosing the Lakers over Raptors: "It was tough. It was very hard. The first couple days were tough for me but once you kind of decide what you want to do next or how you want to go about your next challenge, I thought the right thing to do was go with the Lakers"


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- 1 night
1 Room, 1 Adult
Chicago South Loop Hotel
Renovated in 2019
Select room
See all 102 photos
Hotel Reviews
Convenient parking, Great location
45 reviews
Wi-Fi in designated areas
Non-smoking floor
Front desk (24 hours)
Hotel Location
- Cermak–Chinatown1.2km
- 35th–Bronzeville–IIT1.8km
- Midway International Airport15.5km
- O'Hare International Airport34.2km
- Chicago Union Station4.6km
- Van Buren St.4.9km
View Map
- 1 night
1 Room, 1 Adult
Hotel Description
- Renovated: 2019
- Number of Rooms: 232

Property Location
With a stay at Chicago South Loop Hotel in Chicago (South Loop), you'll be close to McCormick Place and University of Illinois Chicago. This spa hotel is close to Willis Tower and Skydeck Ledge.

Rooms
Make yourself at home in one of the 232 air-conditioned rooms featuring refrigerators and LCD televisions. Complimentary wired and wireless Internet access keeps you connected, and satellite programming provides entertainment. Private bathrooms with shower/tub combinations feature deep soaking bathtubs and complimentary toiletries. Conveniences include phones, as well as desks and complimentary weekday newspapers.

Rec, Spa, Premium Amenities
Pamper yourself with onsite massages, body treatments, and facials. Additional features include complimentary wireless Internet access, concierge services, and gift shops/newsstands.

Dining
Satisfy your appetite at the hotel's restaurant, which features a bar. Dining is also available at a coffee shop/café. Quench your thirst with your favorite drink at a bar/lounge. Cooked-to-order breakfasts are available daily for a fee.

Business, Other Amenities
Featured amenities include complimentary high-speed (wired) Internet access, a 24-hour business center, and a computer station. Planning an event in Chicago? This hotel has 2500 square feet (232 square meters) of space consisting of conference space and meeting rooms. Free self parking is available onsite.

You must present a photo ID when checking in. Your credit card is charged at the time you book. Bed type and smoking preferences are not guaranteed.Your reservation is prepaid and is guaranteed for late arrival. The total charge includes all room charges and taxes, as well as fees for access and booking. Any incidental charges such as parking, phone calls, and room service will be handled directly between you and the property.

Services & Amenities
Most Popular Amenities
Wi-Fi in designated areasCaféBarNon-smoking floorFront desk (24 hours)GymSpaMassageLuggage storageBeauty salonMeeting roomsMultilingual staffFax/copying serviceBusiness centerATM
- Wi-Fi in designated areas
Transportation Services
- Pickup Service(Bus/Train Station)
- Shuttle service to nearby landmarks
Front Desk Services
- Luggage storage
- Front desk safe
- Concierge service
- Attraction ticket service
- Front desk (24 hours)
- Private check-in/checkout
Food & Drink
- Restaurant
- Café
- Room service
- Bar
- Heating
- Elevator
- Accessible rooms
- Newspaper in lobbyFree
- Non-smoking public areas
- Non-smoking floor
Business Services
- Meeting rooms
- Business center
- Fax/copying service
- Multilingual staff
- Wedding service
Cleaning Services
- Laundry service
- Laundry service (off-site)
Public Area
- Mini shopping mall
- Gift shop
Health & Wellness
- Gym
- Spa
- Massage
- Beauty salon
Need to Know
Important City Info
Guests aged under 21 cannot stay at the hotel alone. Specific policies may vary by hotel and room type.
Guests should provide the credit card when checking in. The hotel will pre-authorize your card and the pre-authorization will be released if there's no extra spending or damage to the room when checking out. Some hotels and room types have special policies, please refer to the hotel.
Hotel Policy
Check-in and Check-out
- Check-in from 15:00
- Check-out before 11:00
Children and Extra Beds
Children are welcome at this hotel.
Chicago South Loop Hotel Frequently Asked Questions
How much does it cost to stay at Chicago South Loop Hotel?
Prices at Chicago South Loop Hotel are subject to change according to dates, hotel policy, and other factors. To view prices, please search for the dates you wish to stay at the hotel.
What is the closest airport to Chicago South Loop Hotel?
The closest airport is Midway International Airport. It is 15.5km from the hotel and approximately a 16minutes journey by taxi.
What are the check-in and check-out times at Chicago South Loop Hotel?
The check-in time is from 15:00 and the check-out time is before 11:00.
Does Chicago South Loop Hotel provide airport transfer services?
No, the Chicago South Loop Hotel doesn't provide airport transfer services.
What amenities and services does Chicago South Loop Hotel have?
Chicago South Loop Hotel has the following amenities and services: Wi-Fi in designated areas, Café, Bar.
Does Chicago South Loop Hotel have a swimming pool?
No, Chicago South Loop Hotel doesn't have a pool.
Does Chicago South Loop Hotel have fitness amenities?
Yes, Chicago South Loop Hotel has fitness amenities.
Does Chicago South Loop Hotel provide free Wi-Fi?
Please view the amenity list on the hotel page.
Does Chicago South Loop Hotel have non-smoking rooms?
Yes, Chicago South Loop Hotel has non-smoking rooms. Please view the hotel listing for details.
Does Chicago South Loop Hotel provide breakfast?
No, Chicago South Loop Hotel doesn't provide breakfast.
Does Chicago South Loop Hotel have a restaurant?
Yes, guests can eat at: Restaurant, Café.
Is parking available at Chicago South Loop Hotel?
Yes, parking is available at Chicago South Loop Hotel.
Does Chicago South Loop Hotel have children's amenities?
No, Chicago South Loop Hotel doesn't have children's amenities.
Where is Chicago South Loop Hotel?
The hotel address is 11 W 26th Street. The hotel is 3.63 km from the city center.
Is Chicago South Loop Hotel close to transport stations?
The closest station is Cermak–Chinatown. It is 1.2km from the hotel. View On Map
Is Chicago South Loop Hotel nearby popular attractions?
Chicago South Loop Hotel is near the following attractions: Monument to the Great Northern Migration(Approximately 791m), Chinatown(Approximately 804m), Chinese-American Museum of Chicago(Approximately 808m).
Does Chicago South Loop Hotel have hot springs?
No, Chicago South Loop Hotel doesn't have hot springs.
Show More
Haven't found the right hotel yet?
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Trevor Noah
Aired at the end of the second night, The Daily Show recapped the first night of the virtual Democratic National Convention, in which many ordinary Americans, politicians and celebrities launched a week-long celebration and call for the action for candidate Joe Biden.
One of the most moving early speakers, host Trevor Noah said, was Kristin Urquiza of Arizona, whose father died of coronavirus in June. "Her only pre-existing condition was to trust Donald Trump," she said of her father, adding that he felt "betrayed" by the president at the end of his life.
"Wow, that was absolutely scathing," Noah said of his remarks. "And she's right, she thinks Donald Trump is truly one of the most harmful things you can do." This fact was true even before Trump was president, he added – "just ask Atlantic City, his first two wives, or any other Trump University graduate.
But the real highlight of the first night was former first lady Michelle Obama's speech, in which she calmly declared Donald Trump unfit to lead. Obama's words were both 'bright' and 'icy', Noah said, "and what made them even more devastating was that Michelle Obama wasn't angry – she wasn't screaming, she just declared Trump's complete failure as president as president. obvious fact ".
Noah also appreciated that Obama "doesn't shame people. In recent years, it has been common in politics to shame people who disagree with you and do not intend to vote like you. Much of this is fueled by the toxicity of the online culture and the current division of the country, but instead of doing so, Michelle acknowledged that there are people who don't want to hear what she has. to say, then she respectfully. and seriously engaged with those who might want to listen to him, and asked them to support Biden.
Trump, of course, did not respond well to Obama's words; at an event celebrating the centenary of women's suffrage, he criticized her speech for being recorded instead of live. "Not only was it recorded," he said, "but it was recorded a long time ago because she had [coronavirus] death. "
"Damn, he's one of the biggest self-owns I've ever seen," Noah replied, then imagined Trump's logic: "One hundred and fifty thousand dead? I've killed 20,000 more since then, idiot!
Stephen Colbert
For the second night in a row, Stephen Colbert covered the highlights of DNC live immediately after the virtual broadcast. The theme for the first night was 'we the people', while the second night turned to 'leadership issues' – 'which, of course, forced the GOP to rename the second night of their convention' every day. qualities matter, "Colbert joked.
The second night of the convention was a "magical night," he continued, which included segments on women's suffrage, the health crisis in the United States and a "beautiful travelogue from Joe Biden's hairline – he's obviously had quite a trip in the last 50 years ".
Keynote speakers for the evening included former Presidents Jimmy Carter and Bill Clinton, who called Trump's Oval Office a "storm center" rather than a command center.
"That's a good point, but I don't think Bill Clinton can lecture anyone about what should happen in the Oval Office," Colbert replied. "Those who live in glass houses should not be allowed to approach the interns."
Several speakers referred to Tuesday's anniversary marking the centenary of women's constitutional suffrage through the 19th Amendment. "Fun fact: My mom was born three days after women first got to vote," Colbert said of the occasion. "This is how recently [this was]. Another fun fact: Women have been able to vote for 100 years – Joe Biden has been in office for half that time.
Jimmy Fallon
And on The Tonight Show, Jimmy Fallon recapped Michelle Obama's widely acclaimed speech Monday night, in which she used Trump's words against him. Calling Trump "the wrong president for our country," Obama said he had "had more than enough time to prove he could do the job, but he was clearly over his head. He cannot meet this moment. He just can't be the one we need for us. It is what it is. "
"At that point, Donald Trump squeezed his diet coke so hard it turned into a diamond," Fallon said. "I'm serious, right after that a doctor took Trump's blood pressure and the cuff blew up.
Trump was asked about Obama's "over-the-head" comment at an event celebrating the centenary of the 19th Amendment, and replied, "She's over-the-head." "
"Oh, yeah, it's a good comeback," Fallon scoffed. "It was his insult to you. You can't use his insult – every third grader who can't go back to school the next day knows that.


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Smart Reasons To Sell Your Home This Winter
If you're looking to sell your home, the winter is the perfect time to do so. Read below to find out the smart reasons on why you should sell your home this winter!
Interested in selling your home this winter? Contact Mark Spain Real Estate today!
Smart Reasons to Sell Your Home This Winter
Less Competition
Since Spring is generally the most popular time to sell a home, try selling in the winter! The housing market experiences less inventory in the cold months. With less inventory for buyers to choose from, this means less competition for you as a seller! There are fewer homes for sale in the winter, making this an ideal time to list your home on the market. In fact, sources say that January is one of the best times for homes to go under contract in the Atlanta market! Less competition also means that buyers may not be able to negotiate better terms, meaning you could get your full asking price or higher!
Serious Buyers
The winter months bring in the most serious home buyers. With more down time for buyers, they are able to do intense searching for their dream home. This is the time when buyers are seriously looking to make a purchase, and not just window shopping. When buyers find a home they like, they have to snag it before it's gone, considering the high competition between buyers when there's low inventory.
Financial Stability
With many people experiencing year end bonuses and payouts, buyers may have more money to spend on a home. This is an opportunity for buyers to find their dream home, and even splurge on upgrades or increase their spending budget!
Showing Your Home in the Winter
The winter months are the perfect time to show your home's readiness for the harsh elements. For example, showcasing the working condition of the heater and fireplace during a home showing, or emphasizing the new roof! With more downtime during this season, buyers are able to do more in person home showings to get a better feel of the home as well.
Do these reasons make you want to sell your home in the winter? If so, contact us today and start packing!


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