text:
It's time to socialize!
The Prime Times Social Club holds free monthly meetings on a wide variety of topics meant to educate and entertain, with complementary refreshments provided by Altra. Group outings are also scheduled throughout the year.
Who can join?
The Prime Times Social Club is sponsored by Altra Federal Credit Union and is open to all La Crosse, WI area residents age 50 and over. There is no cost to join and Altra Federal Credit Union membership is not required. Guests are always welcome to attend.
How do I join?
It's easy! Just provide us with your email or mailing address. You'll receive a monthly Prime Times newsletter with helpful consumer information, financial tips, and upcoming event & seminar information.
Find us on Facebook!
The Altra Prime Times Club has a Facebook page, and you are welcome to post items to it! Visit us on Facebook to access the page, find upcoming event info, view pictures of events and more!
Suggestions & Questions
If you have any questions or suggestions for speakers or future events, please contact Dawn at [email protected] or call 608-787-4500.
|Wednesday, June 6, 2018
Annual Summer Picnic
|July 2018
|No Meeting
Summer Break
|Wednesday, August 1, 2018
|La Crosse Queen Riverboat Cruise
Riverside Park, La Crosse, WI
RSVP Required
|Thursday, September 27, 2018
|Oktoberfest Senior Breakfast
South Side Oktoberfest Grounds, La Crosse, WI
|Wednesday, November 7, 2018
|River Valley Raptors
Inspiring Conservation through Education
Altra Operations Center, Onalaska, WI
|December 2018
|Annual Holiday Luncheon & Live Entertainment
Radisson Hotel, La Crosse, WI
RSVP Required


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How do you make your website known? It takes a lot of time and effort in order for your site to be listed at least in the first page when someone puts in a keyword in a search engine. You need to have a huge number of sites that have links pointing to your site. So how do you make other website owners include your link in their website? This is where the process of link building comes in. Link building is very good in marketing your products or services because it promotes traffic for your website. Here is some free software that you can use to help you in link building, along with the links to download the programs.
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How To Do Things. Copyright Howtodothings.com © 2016, all rights reserved.

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Jeffrey McGlone
Windham High Windham, OH Class of 1983
Personal Info
- Name:
- Jeffrey McGlone
- Graduation Year:
- 1983
Register to view Current location, Gender, Birthday, Relationship Status, Children, Employer, Military, College, and Interests
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What I'm doing now:Register to see what Jeffrey McGlone is up to now!
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|- Registered as a WHS Class of 1983 alumni. 2009


text:
After much explanation that no toads were harmed in the making of this dish, we ate it for tea, with some courgettes, sweetcorn and peas. There was a lot of explaining about Yorkshire pudding too.
You'll need:
sausages - we had about 14 little skinny thinny Cumberland ones
2 eggs
150g plain flour
150ml milk, mixed with 150ml water
a teaspoon of grainy mustard
a little sunflower oil
You need the oven good and hot, so stick it on at about 220 degrees C before you start.
In a bowl, whisk together the eggs, flour, milk and mustard, until it's stopped being hideously lumpy. According to the God of all sausage dishes, Nigel Slater, you want the batter to be the consistency of double cream, so depending on how large your eggs are, you may have to add a little extra flour.
Now your oven's hot, stick your toad in the hole pan(s) in, with a dollop of sunflower oil in the bottom. I used muffin tins today, to make mini toads, but you could just bung the whole lot in a baking dish (in which case you'll need a couple of tablespoons of oil in the bottom).
Once the oil's hot (should take just a couple of minutes), add the batter to each tin (it should sizzle nicely), and drop the sausages in. Try not to get spattered by any hot fat...
Bake in the oven for about 30-40 minutes, depending on the size of your sausages and how crispy you like your Yorkshire pudding.


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February 1st, 2019
Author: April Bullard |
706-542-4847 |
More about April
A weekly digest of news, events, and opportunities for all undergraduate FACS students.
Friday, February 1, 2019
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The Career Center partners with employers in Atlanta and Athens to provide a job shadow opportunity to match your career interest. Students who participate are able to build their resume, explore a career and network with professionals.
How to participate in Intern for a Day?
Attend a mandatory info session:
February 6th, 4:00 – 5:00 p.m., Miller Learning Center Rm. 171
February 7th, 4:00 – 5:00 p.m., Miller Learning Center Rm. 171
February 11th, 4:00 – 5:00 p.m., Miller Learning Center Rm. 171
For more details and to view the list of participating employers (beginning 2/4), please visit http://career.uga.edu/job_search/internships/intern_for_a_day_application
Career Center Events Next Week:
Pre-Health Personal Statement Writing Lab
February 4th; 3:30 - 5:00 p.m.; Career Center - Clark Howell Hall, 2nd Floor
If you're applying to OT, PT, PA, medical, dental, or any health profession school, it's time to start thinking about writing your personal statement. In this small group session, we'll discuss what admissions committees look for in personal statements and go over techniques to improve your writing skills. You'll walk away with tangible resources to help you begin or improve your personal statement. Bring a pen or your laptop and be ready to write. Labs are limited to 25 students; must register in advance on Handshake to attend.
Arch Ready: Interviewing
February 4th; 4:00 - 5:00 p.m.; Miller Learning Center, Rm. 171
College of Environment and Design Career and Internship Fair
February 5th; 12:00 - 3:00 p.m.; Tate Student Center – Grand Hall, 5th Floor
Journalism and Mass Communication Career Day
February 7th; 2:00 - 5:00 p.m.; Tate Student Center – Grand Hall, 5th Floor
Arch Ready Express Workshop: How to Network
February 7th; 2:30 - 3:00 p.m. or 3:00 - 3:30 p.m.; Career Center - Clark Howell Hall, 2nd Floor
See link for more details. Pre-registration is required.
Save the Date
UGA Diversity & Inclusion Career Conference
February 19th; 3:00 - 8:15 p.m.; Tate Grand Hall – 5th Floor
See link for more details. Pre-registration required.
4. FACS Events Pick of the Week!
10 Outstanding Senior Leaders will be featured in this year's Pandora Yearbook. If you are a senior who has exemplified great honor and integrity, apply to be an OSL! Applications are due February 11th, at 5:00 p.m. Visit the Involvement Network for more information.
Bulldog Basics is a student-led initiative supported by FACS. A variety of personal hygiene items are available for students to access as needed. Bulldog Basics is funded by a UGA Sustainability Grant awarded fall 2016 and by a UGA Parents and Families Leadership Council Grant, awarded in spring 2017. Item donations are accepted in the Student Success and Advising Center (112 Dawson Hall).
Hours: Check the Bulldog Basics website
6. 2019 FACS Student Ambassadors – Applications Open
Are you interested in serving as a FACS Student Ambassador? You can find more information and the application here. Applications are due February 22nd!
7. McPhaul Center – Construction Update
Sewer repair work located at the quad between Family Research Centers 1 & 2, Consumer Research Center, and the Charles Schwab Financial Planning Center has begun. This work is estimated to last 3 to 4 weeks, during this time the quad/sidewalks between buildings will be inaccessible. If you have any other questions or concerns, please feel free to contact Joe Nageotte.
FACS Destination of the Week: Bolivia
About Bolivia! If you would like to study away while touring a beautiful country, then this is the program for you! The Bolivia study away program is great way for students to engage in a different culture while working in the healthcare field. This program gives students the opportunity to learn about Bolivia's healthcare system, while working alongside dieticians and nutritionists. Students will even have the chance to live with a local family to get a clearer view of a background different from their own. Studying away in Bolivia will give you the helpful experience needed in areas of people and health. The Bolivia study away program dates are May 13th, 2019 – June 2, 2019. Spots are limited!
Class Credit! Students are able to earn 3 - 6 hours of class credit for FDNS. To see the list of the courses offered, please click here.
Application! To apply, please visit the FACS Study Away in Bolivia website or contact Silvia Giraudo .
Scholarships! The deadline to apply for FACS Study Away scholarships has passed. For more information regarding funding and scholarships, please visit the Office of Global Engagement website.
FACS Club of the Week presents: The Agency
What is The Agency? The Agency is a student run organization catered to students who share an interest in fashion and modeling. This club not only gives students the opportunity to network and build relationships with one another, but students will also be able to put their creative skills to the test. Members of The Agency are able to gain hands on experience while working with other organizations throughout the university. This club is a great way to be more involved as a FACS major!
Benefits of Becoming a Member! Through The Agency, students will work within the modeling and the fashion industry. Photographers, make-up artists, and models are all roles that equip students with the skill and knowledge needed for such careers. Not only is this a great way to explore your craft, but this is a great way to build your resume!
Join! All students interested in fashion and modeling are welcomed! To become a member, please contact one of the Jaleesa Reed!
Already a Member? Be More Involved! The Agency works with many organizations across campus. The Agency organizes three photoshoots per semester, and hosts an annual fashion show. Both are ways to stay involved!
10. Follow Us On Social Media!
Stay connected with FACS!
Follow @ugafacs on Instagram and Facebook for posts you don't want to miss!
Facebook: facebook.com/ugafacs
Instagram: instagram.com/ugafacs
New to FACS? View FACS Connection Archives here!
Items for FACS Connection should be submitted by 5:00 p.m. on Wednesdays. Instructions on formatting a FACS Connection entry can be found here.
The Student Success and Advising Center (SSAC) is now accepting internship applications
Leaders and advocates highlight the importance of family and consumer sciences
How the end of our time at Ridge and this program helped me narrow my focus
Finding the light in situations where the resources are limited.
A story about how my first OR experience changed the trajectory of my future


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text: MLS Search 5 Bed / 5 Bath Home in Tanners Mill CirGainesville, GA 30507-8839$16500000Spectacular property and residence that is maintained to perfection. Within an hour you arrive to 446 acres of rolling, fenced pastures, a winding river with waterfalls and lake all surrounding the main residence built of stone and a very rare red slate roof. The rolling hills, pastures, lake and the North River make this a spectacular development opportunity. Included is an equestrian center or car barn and 2 caretaker homes. Property can be subdivided with the house and 50-100 acres. The rest can be developed with the car barn that could be used as a recreation center for the development.SummaryMLS #8438809Price16500000Bedrooms5Bathrooms (Full)5StatusActiveFeatures4 Bed / 7 Bath Home in None1103 Apple Pie Ridge RdAlto, GA 30510$12750000Situated on 1128 acres, this luxurious North Georgia Blue Ridge Mountain home comes with custom architecture and modern finishes throughout. The "Private Island Retreat" comes with stables, barn, a caretaker apartment and abundunt riding trails. On the amazing grounds you have a second caretaker home or guest cottage, gardens overlooking the mountains, waterfalls and a fishing pond. Utmost privacy! Truly Special!!SummaryMLS #8330188Price12750000Bedrooms4Bathrooms (Full)7Square Footage11828Square Footage SourcePublic RecordStatusActiveFeatures9 Bed / 14 Bath Home in None4965 Butner RdAtlanta, GA 30349$12500000Gated Main Entry. English Manor Full finished basement, 8 car garage, 1 Boat/ATV, Pool House and Carriage House, 16.2 acres, w/stocked lake, Exclusive estate feature main foyer spectacular curved staircase, barrel ceiling, Formal living and dining rooms, w/2 FPs, Oversized windows w/natural light, slate roof, copper gutters, Master Suite, morning bar main level, his & her closets, dressing rom, Elevator, Grand foyer, parlor, Gourmet Kitchen, Butler Kitchen, Terrace level w/entertainment rom, FP, oversized bar, Theater, bedroom, more, more.SummaryMLS #8354537Price12500000Bedrooms9Bathrooms (Full)14Square Footage0Square Footage SourceBuilder PlansStatusActiveFeatures6 Bed / 11 Bath Home in Tuxedo Park3800 Northside DrAtlanta, GA 30305$12500000Masterpiece! 3.5 acre estate in Buckhead's Tuxedo Park! Exquisite English Manor Mansion with spacious terrace level, pool house, infinity pool and patios with outdoor living space. 2 story foyer opened to a pair of arched staircases on both sides overlooking the two story great room with wall of windows overlooking pool and open to kitchen. 2 story master with fireplace, separate closets for him and her. Terrace level includes entertainment, media, exercise & spa. 2 story Pool house is unbelievable with bedroom and bath on lower level. Welcome to Buckhead's Finest!SummaryMLS #8482616Price12500000Bedrooms6Bathrooms (Full)11Square Footage0Square Footage SourceBuilder PlansStatusActiveFeatures5 Bed / 6 Bath Home in None301 Kemp RdSuwanee, GA 30024$10600000One of four homes on 191+/- acres of pristine nature to enjoy with family and friends for years to come. This wonderful home has a very open floor plan. Beautiful exterior of stone and wood. Large master is on the main level, 3 bedrooms upstairs, finished terrace level, & full apartment over the garage, From the front door you can hike,or ride miles of trails winding through beautifully wooded property. Currently on property are 2 barns, 2 riding rings, and cross country course. Located close to everything, but extremely private. The possibilities are limitless on how to enjoy this breathtaking landSummaryMLS #8485159Price10600000Bedrooms5Bathrooms (Full)6Square Footage7258Square Footage SourceSq Ft Not EnteredStatusActiveFeatures5 Bed / 5 Bath Home in Tanners Mill Estate3509 Tanners Mill CirGainesville, GA 30507-8839$9900000Spectacular custom built residence, car barn and 130 acres available. Rolling pastures, lake and river surround the residence. The quality of construction is superb from the wide plank flooring to reclaimed beams and solid doors. Floor to ceiling glass in the living room open outside to covered patios. Perfect pool site! The master wing and sitting room open to the patios. The collector car barn is ranked in the top 5 in the country & features an entertainment/bar area for viewing. Can easily be converted back to an equestrian riding ring & stables.SummaryMLS #8491792Price9900000Bedrooms5Bathrooms (Full)5Square Footage0Square Footage SourcePublic RecordStatusActiveFeatures7 Bed / 9 Bath Home in GA1291 Braswell RdRockmart, GA 30153$9750000This all-inclusive Estate is a part of a working cattle ranch with Manager's home, barn, & hunting cabin. Would also make a perfect vineyard or hunting retreat. Multiple land parcels. Silver Comet Field at Paulding NW Airport is 6 miles away. Polk County Airport Cornelius Moore Field is 15 miles away. 3 spring-fed lakes & numerous springs throughout property. Pasture has 14 separate cross-fenced pallets, all with livestock watering. Property adjoins the State of Georgia Wildlife Management area on north & east sides. 5 acre lake behind home. 1 mile creek frontage. Roads & ATV trails throughout pasture & timber acreage. Over 1 mile of road frontage. 220 open grassed acres. This magnificent property includes main Estate home, Hills Creek Event Facility.SummaryMLS #8413799Unit NumberBPrice9750000Bedrooms7Bathrooms (Full)9StatusActiveFeatures8 Bed / 9 Bath Home in None1401 Bullard RdPowder Springs, GA 30127$9750000Breath-taking French country manor home on a 46 acre world class equestrian estate. Spectacular home features great stone fire places, old growth walnut floors, and old growth cypress coffered ceilings. Exquisitely landscaped gardens surround a custom pool and pool house. The equestrian facility boasts a custom fully equipped 12 stall barn, riding arena with viewing deck. An historic 1867 farm house serves as the caretaker's home. 15 minutes to The Marietta Square, 20 minutes to the Battery Atlanta, and 45 minutes to Hartsfield-Jackson International Airport.SummaryMLS #8450616Price9750000Bedrooms8Bathrooms (Full)9Square Footage14791Square Footage SourceSq Ft Not EnteredStatusActiveFeatures7 Bed / 9 Bath Home in None1291 Braswell RdRockmart, GA 30153$9750000Spectacular Estate Home settled on 780+ acres located in Northwest Georgia at the foothills of the Appalachian Mountains. Home boasts of Seven bedrooms, seven full baths, and two half baths. Finished on all three levels with full kitchen on both main and pool levels. Landscaped pool with waterfall and spa which sits over lake with gazebo on island with bridge. Property includes Hills Creek Event Facility originally a Cattle Sales Barn situated on Georgia's most beautiful farmland, rolling hills, winding creeks and hardwoods. 3 spring-fed lakes. Numerous springs throughout property. Pasture has 14 separate cross-fenced pallets all w/livestock watering. Property adjoins the State of Georgia Wildlife Mgt. area on north and east sides. 5+ acre lake behind home.SummaryMLS #8413837Price9750000Bedrooms7Bathrooms (Full)9Square Footage10357Square Footage SourcePublic RecordStatusActiveFeatures6 Bed / 9 Bath Home in None4615 Northside DrAtlanta, GA 30327-4549$9395000A stunning gated, private estate with 9+ acres of dramatic, landscaped grounds complete with gardens, paths, ponds, & unique outdoor venues. Built in 1990 in Georgian style, the home features elegantly appointed rooms with classic scale and fine millwork. Entertaining is easy with 2 formal bars on either side of the grand foyer. The formal living room, dining room, and galleries open to the expansive limestone terrace and formal gardens. Gourmet "cook's" kitchen & large family room open to the play yard, pool & tennis court. 48 hours notice & proof of funds requiredSummaryMLS #8444994Price9395000Bedrooms6Bathrooms (Full)9Square Footage13400Square Footage SourceOther (See Remarks)StatusActiveFeatures1 Bed / 1 Bath Home in None220 Sam RdNewnan, GA 30265$8000000Craftsman style loft overlooking 25+- acre lake on 328 +- acre tract close to Piedmont Newnan Hospital. Survey at buyer's expense will determine exact acreage. Property is gated, call agent for code. Ask about the Coweta Greenway Plan and Rails to Trails! If Listing Agent shows property without Buyer's Agent being present, selling commission is reduced on the Buyer's side to 1%SummaryMLS #8363503Price8000000Bedrooms1Bathrooms (Full)1Square Footage0Square Footage SourceSq Ft Not EnteredStatusActiveFeatures6 Bed / 9 Bath Home in Lake Burton2458 Moccasin Creek RdClarkesville, GA 30523$7995000Designed by PRITCHETT+DIXON architects, this expertly crafted 6 BD, 7 fb and 2 hb Lake Burton home was completed in 2018. Built as a contemporary Timber Frame Lodge with cypress timbers and granite stone, the clean-lined interior features custom mill-work and ship lap paneling. Westerly views of the lake and distant mountains are enjoyed throughout the home. The main floor owner's suite offers a lakeside porch and spa-like bath. Four additional guest suites plus a bunk room provide ample room for guests. Amenities include professional appliances, elevator, nanawalls, generator, 2-car garage and 2-story boathouse.SummaryMLS #8492839Price7995000Bedrooms6Bathrooms (Full)9Square Footage8189Square Footage SourceOwner/SellerStatusActiveFeatures6 Bed / 12 Bath Home in North Buckhead40 Cates Ridge RdAtlanta, GA 30327-4425$7950000Incredible resort-feel estate in North Buckhead that borders State land and the Chattahoochee River. This location is extremely desirable and a lower tax base but minutes to Buckhead. Very private and secure with front and back gates on the property. The 3 parcels that make up this property total 8.4 manicured acres. Complete with golf cart paths, walking trails, waterfalls to the lake, tennis, batting cages and new pool with spa. The main house, guest cottage and caretakers house are all on the latest Control 4 technology. Interiors are light and airy. Generator.SummaryMLS #8468018Price7950000Bedrooms6Bathrooms (Full)12Square Footage16694Square Footage SourceAppraiserStatusActiveFeatures5 Bed / 11 Bath Home in None795 Highcourt RdAtlanta, GA 30327$7950000Private luxurious European gated estate located on nearly 6 acres of beautifully manicured gardens. Stunning foyer with soaring ceilings that open to living room with views of the infinity pool and outdoor terrace. Travertine and hardwood floors, Brazilian walnut doors, spacious gourmet kitchen with keeping room. Master on main with enormous his and her closets, fireplace and sitting area. 4 large bedrooms upstairs, finished daylight terrace level with wine cellar. 4 car garage.SummaryMLS #8332942Price7950000Bedrooms5Bathrooms (Full)11Square Footage22000Square Footage SourceOwner/SellerStatusActiveFeatures15 Bed / 10 Bath Home in GA13835 Hopewell RdAlpharetta, GA 30004$7499900Exciting News! Seller is including everything! A 10000 sqft Cape Cod home, 1600 sqft private guest house, 4500 sqft workshop/RV barn, all adding up to 30 acres. A must see property. 38 stall barn, which was constructed and furnished with the greatest attention to detail imaginable. From the stacked stone walls, pillars and arches to the 160' by 300' covered and lit arena with 16 "AA" show quality jumps, this barn is truly one of a kind. The barn boasts 8 wash stalls as well, complete with heated water and fans and area heaters for seasonal comfort.SummaryMLS #8346403Price7499900Bedrooms15Bathrooms (Full)10StatusActiveFeatures4 Bed / 8 Bath Home in 3307 Sandy Flats RdCleveland, GA 30528$6900000INCREDIBLE GENTLEMAN'S ESTATE IN WHITE/LUMPKIN CO 546 METICULOUSLY MAINTAINED ACRES TWO HOMES, 8000 SF SHOP, POWER PLANT, 1.5 MILES RIVER, 6 ACRE LAKE.SummaryMLS #3178809Price6900000Bedrooms4Bathrooms (Full)8StatusActiveFeatures2 Bed / 2 Bath Home in Apple Pie Ridge RdAlto, GA 30510$6750000This landmark property is situated on 978 acres in North Georgia overlooking the Blue Ridge Mountains. This private island retreat comes with private stables, barn with caretaker apartment and abundant riding trails. A second caretaker home or guest cottage is also on the grounds along with water falls, vineyards/gardens and a large fishing pond! This property can be purchased with GAMLS #8329556 to add additional acreage and a luxurious custom architectural home.SummaryMLS #8329911Price6750000Bedrooms2Bathrooms (Full)2StatusActiveFeatures8 Bed / 11 Bath Home in None1865 Bethany WayMilton, GA 30004$6599000Newly updated, one-of-a-kind, 26 acre lakefront Chathambilt estate designed by Stephen Fuller. Breathtaking setting and views can only be appreciated in person. Uncompromising attention to detail, design and quality. Gated, carriage house, 6 car garage, pool, basketball and tennis, theater, 2 pastures. Located just 5 minutes from Downtown Alpharetta but the true Milton feel.SummaryMLS #8268990Price6599000Bedrooms8Bathrooms (Full)11Square Footage18984Square Footage SourceAppraiserStatusActiveFeatures4 Bed / 5 Bath Home in Waldorf Astoria Residences3376 Peachtree Rd NEAtlanta, GA 30326$6500000This privately owned TOP FLOOR penthouse SHELL is now available for your most discerning buyers. Buyers can design a home specific to their needs and lifestyles. With its discreet setting, dedicated 24-hour staff & state-of-the-art security, this 2 story spectacular duplex penthouse is a haven of consummate privacy. Residents & their guests enjoy use of a private entrance & lobby area, as well as a private parking garage & resident-only elevators. Pricing is for shell space only. 4 primo parking spaces and 2 large storage units included w/ sale.SummaryMLS #8498443Unit NumberPH 58Price6500000Bedrooms4Bathrooms (Full)5Square Footage0Square Footage SourceSq Ft Not EnteredStatusActiveFeatures6 Bed / 11 Bath Home in Trinity Church1850 Trinity Church RdCanton, GA 30115$6500000Unmatched property and custom estate nestled in Southern Cherokee County! Situated on 67 acres with stocked lake and over 30 acres of pastures with easy access to private air travel. Carriage house features luxury apartment and climate-controlled area perfect for specialty car collection. From entry you are struck by the classic elegance and superior craftsmanship. Indoor spaces flow seamlessly to outdoors like the infinity pool pouring into the kaleidoscope of colors in the never-ending landscape. Breathtaking views from each room frame snapshots of a Hallmark movie.SummaryMLS #8526542Unit Number#A-67Price6500000Bedrooms6Bathrooms (Full)11Square Footage0Square Footage SourceOwner/SellerStatusActiveFeatures custom hotsheet


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Anti-TGF beta Receptor II antibody (ab17650)
- Datasheet
- References (1)
- Protocols
Product nameAnti-TGF beta Receptor II antibody
See all TGF beta Receptor II primary antibodies
DescriptionSheep polyclonal to TGF beta Receptor II
Host speciesSheep
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Chicken
Fusion protein, corresponding to amino acids 27-85 of Chicken TGF beta Receptor.
General notes
Antibodies directed against TGF beta receptor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.08% Sodium azide
Constituent: PBS
Concentration information loading...
PurityImmunogen affinity purified
Primary antibody notesAntibodies directed against TGF beta receptor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion.
Research areas
Associated products
Isotype control
Our Abpromise guarantee covers the use of ab17650 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|1/100. Predicted molecular weight: 63 kDa.
|Use at an assay dependent dilution.
FunctionTransmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.
Involvement in diseaseDefects in TGFBR2 are the cause of hereditary non-polyposis colorectal cancer type 6 (HNPCC6) [MIM:614331]. Mutations in more than one gene locus can be involved alone or in combination in the production of the HNPCC phenotype (also called Lynch syndrome). Most families with clinically recognized HNPCC have mutations in either MLH1 or MSH2 genes. HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (CRC) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the Western world, and accounts for 15% of all colon cancers. Cancers in HNPCC originate within benign neoplastic polyps termed adenomas. Clinically, HNPCC is often divided into two subgroups. Type I: hereditary predisposition to colorectal cancer, a young age of onset, and carcinoma observed in the proximal colon. Type II: patients have an increased risk for cancers in certain tissues such as the uterus, ovary, breast, stomach, small intestine, skin, and larynx in addition to the colon. Diagnosis of classical HNPCC is based on the Amsterdam criteria: 3 or more relatives affected by colorectal cancer, one a first degree relative of the other two; 2 or more generation affected; 1 or more colorectal cancers presenting before 50 years of age; exclusion of hereditary polyposis syndromes. The term "suspected HNPCC" or "incomplete HNPCC" can be used to describe families who do not or only partially fulfill the Amsterdam criteria, but in whom a genetic basis for colon cancer is strongly suspected. HNPCC6 is a type of colorectal cancer complying with the clinical criteria of HNPCC, except that the onset of cancer was beyond 50 years of age in all cases.
Defects in TGFBR2 are a cause of esophageal cancer (ESCR) [MIM:133239].
Defects in TGFBR2 are the cause of Loeys-Dietz syndrome type 1B (LDS1B) [MIM:610168]. LDS1 is an aortic aneurysm syndrome with widespread systemic involvement. The disorder is characterized by arterial tortuosity and aneurysms, craniosynostosis, hypertelorism, and bifid uvula or cleft palate. Other findings include exotropy, micrognathia and retrognathia, structural brain abnormalities, intellectual deficit, congenital heart disease, translucent skin, joint hyperlaxity and aneurysm with dissection throughout the arterial tree.
Defects in TGFBR2 are the cause of Loeys-Dietz syndrome type 2B (LDS2B) [MIM:610380]. An aortic aneurysm syndrome with widespread systemic involvement. Physical findings include prominent joint laxity, easy bruising, wide and atrophic scars, velvety and translucent skin with easily visible veins, spontaneous rupture of the spleen or bowel, diffuse arterial aneurysms and dissections, and catastrophic complications of pregnancy, including rupture of the gravid uterus and the arteries, either during pregnancy or in the immediate postpartum period. LDS2 is characterized by the absence of craniofacial abnormalities with the exception of bifid uvula that can be present in some patients. Note=TGFBR2 mutations Cys-460 and His-460 have been reported to be associated with thoracic aortic aneurysms and dissection (TAAD). This phenotype, also known as thoracic aortic aneurysms type 3 (AAT3), is distinguised from LDS2B by having aneurysms restricted to thoracic aorta. As individuals carrying these mutations also exhibit descending aortic disease and aneurysms of other arteries (PubMed:16027248), they have been considered as LDS2B by the OMIM resource.
Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain.
modificationsPhosphorylated on a Ser/Thr residue in the cytoplasmic domain.
Cellular localizationCell membrane.
- Information by UniProt
Database links
- Entrez Gene: 396399 Chicken
- SwissProt: Q90999 Chicken
Alternative names
see all
- AAT3 antibody
- FAA3 antibody
- LDS1B antibody
Datasheets and documents
This product has been referenced in:
- Qiu X et al. TR4 nuclear receptor increases prostate cancer invasion via decreasing the miR-373-3p expression to alter TGFßR2/p-Smad3 signals. Oncotarget 6:15397-409 (2015). WB . Read more (PubMed: 25980442) »


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Take Violin Lessons in Singapore to Master this Instrument
Violin is a popular musical string instrument. People love to learn this instrument and play melodious tunes that tug at the strings of heart. These days, Violin Lessons are readily available in Singapore. Seeking these classes can help them gain a lot of advantages. With the internet use increasing rapidly, many companies offer an online violin class that allows students to learn playing violin while sitting in the comfort of their home.
The major benefit that can be enjoyed by engaging the services of a Violin Teacher in Singapore is the affordable rates at which the same can be availed. The teachers hired by these music schools are highly experienced and expert in their field. They can help the students get a hang of this tricky instrument in a simple and systematic manner. Moreover, the teachers hired by the schools are usually highly reputed and well-known.


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Food & Drink
Beauty & Health
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Organic India, Indira Nagar, Bangalore
This Organic India store is a company owned store that offers all the company's products. The products include Organic Honey, Ghee, different Green
Location: #4, Chinmaya Mission Hospital Rd, Opp to Shanthi Sagar Hotel, Indiranagar, Bengaluru, Karnataka 560038Website: https://www.organicindia.com/Phone: 087928 33207
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Nisarga Shoppe Organic Store
Nisarga Shoppe offers the product range include different varieties of unpolished rice, millets, pulses, spices, pickles, jams, paneer made from whole
Location: Suite 'G', Inside Lake View Farm, Siddhapura, Adjacent to Miraya Rose Apartment Next to Shell Petrol Bunk, post, Varthur Rd, Whitefield, Bengaluru, Karnataka 560066Website: https://www.nisargashoppe.comPhone: 91 - 80 - 28542897
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Fresh Organic World - Boopasandra Main Road
Fresh Organic World is located at Boopasandra Main Road, Bangalore.
Location: #60, NTI Bus stop, Boopasandra Main Road , R.M.V 2nd Stage, Bangalore - 560094Phone: 9620631592
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Krushika Organics - Organic Food Store in Banswadi
Krushika Organics is an Organic Food Store in Banswadi, Bangalore.
Location: No 2C-742, Basement, 9th Main, 1st block, HRBR Layout, Banasawadi, Bangalore - 560043Website: https://krushika-organics.business.site/Phone: 8884158880
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The PicoBoard allows you to create interactions with various sensors. Using the Scratch programming language, you can easily create simple interactive programs based on the input from sensors. The PicoBoard incorporates a light sensor, sound sensor, a button and a slider, as well as 4 additional inputs that can sense electrical resistance via included cables.
Designed for educators and beginners, the PicoBoard is a good way to get into the very basics of programming and reading sensors.
Be aware that four sets of alligator clips are included, however a miniUSB cable is not included. If you don't already have a miniUSB cable lying around make sure to pick one up. You can find the SparkFun miniUSB cable in the Recommended Products section below.
Note: The PicoBoard is a derivative work of the Scratch Sensor Board.
Resistors are a good thing, in fact, they're actually crucial in a lot of circuit...
These are 6" long jumper wires with female connectors on both ends. Use these to...
These are 6" long jumper wires with male connectors on both ends. Use these to...
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Posts Tagged 'Seattle Parks and Recreation'
A Few Great Seattle Parks You Might Not Know About
July 28th, 2018 by Kristen Cramer
Seattle is home to many amazing parks and the big ones, such as Volunteer Park, Discovery Park, and Carkeek Park seems to get most of the praise. However, there are several lesser-known parks that provide plenty of things to do and beauty to enjoy. The Seattle Parks and Recreation actually maintain more than 400 parks […]


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Tropical fruit from all over Krawk Island is gathered cut and thrown into this pot. It is perfect for parties and very healthy.
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We provide Mobile DJ & Music workshops to a variety of educational and non-educational establishments, charities, communities, organizations and offer Private DJ Hire.
We also provide affordable studio bookings, private tuition and band workshops.
ProBeatz is passionate in supporting and working alongside community groups. We are proud partners alongside FORCE5 Education. Our aim is to reach young people who are struggling with formal education and open our facilities to local communities.
KS2 Age 7-11, KS3 Age 11-13, KS4 Age 14-16, KS5 Age 16-18
Bedfordshire, Buckinghamshire, Cambridgeshire, Hertfordshire, Leicestershire, Northamptonshire
Schoolworkshops.com is a directory of workshop providers/third party suppliers advertising
their services to schools or other organisations.
On completing this enquiry form, you may be contacted by a member of the schoolworkshops.com
team to support you with your enquiry. Schoolworkshops.com does not take bookings directly or
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All subsequent enquiries are forwarded to the relevant workshop provider/supplier to contact
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who we feel may meet the needs of your enquiry.
If you choose to book a workshop with a workshop provider/supplier as listed on schoolworkshops.com,
the contract is between the school/organisation and the workshop provider. Schoolworkshops.com
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As a school or organisation it is your responsibility to verify the credentials of a provider
you may be interested in engaging. We suggest you obtain proof of ID, CRB's for all staff, insurance,
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The trade show can be a gold mine for your business, rather it can also prove a real trap any time you do not seize the most out concerning the experience. While a whole lot has been made all about taking along the suited promotional material, getting an best location, and having plenty of business s and other contact info available, there are five secrets tips that might help you get the most important most out of each trade show.
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Korea Institute of Geoscience and Mineral Resources (KIGAM) – Korea MP
In more than 80 years since its establishment as a geological survey of Korea in the early twentieth century for geological mapping and mineral resources exploration, KIGAM has grown into a comprehensive geoscience research institute covering diverse fields to meet the various social needs.
They include not only the basic studies such as geological mapping and mineral exploration, but also the applied ones such as mineral utilization, groundwater evaluation and contamination improvement to prepare against the water shortage in the future and geological disasters to minimize the loss of life and property. KIGAM also studies mining research, underground space utilization, oil and gas exploration, marine geology, geological engineering and recycling of industrial wastes. In addition, as a part of our activities for the public understanding of geoscience, we have opened the geological museum which is the first one in the field in Korea.
KIGAM will develop new technology and diversify its research fields on the basis of its previous researches to cope with the rapidly changing life and industrial circumstances and to aim for the theme of the 21st century, 'Environmental friendliness, Sustainable development and Global system'. We also will try our best to contribute to the enhancement of life quality and the development of industries.We hope contents of homepage will aid you in understanding our institute and activities.


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UWCSEA has a vacancy for May 2019 at its Dover Campus for an Assistant Head of Aquatics.
Responsible for assisting in the successful delivery of the ticketing operations and services.
Using your extensive coaching experience you will be responsible for ensuring that the Centre's Gymnastics program is fun, progressive and engaging!
We are looking for an experienced Partnership Account Manager to join the IRONMAN Oceania team. They will be responsible for developing, servicing and maintaining corporate and government relationships, as well as managing all sponsorship requirements for their portfolio of events.
The Security Manager will be responsible for development, coordination and delivery of security plans.
Playing a key role in delivering our Tournament vision of a Spectacular Celebration that brings generations and cultures together.
This is a great opportunity to oversee all operational aspects of the brand new Adelaide ATP/WTA Tournament and ensure event readiness both on and off the court.
Imagine a world where you socialise with people, make new friends and get to play social sport… and get paid for it. If this sounds like your dream job then learn more about becoming the new face of SportUP Brisbane as our new Competition Manager.
Responsible for running Bowls Australia events and competitions and building strong relationships with various bowls stakeholders.
Hockey Australia is the national sporting organisation charged with the delivery and governance of Hockey in Australia. Hockey Australia has offices in Perth and Melbourne, with the Melbourne office responsible for the administration of the sport.
ATC is looking for an experienced Functions, Events & Operations Manager to join the team at Rosehill Gardens Racecourse. Be a key player for large scale events such as Golden Slipper, The Golden Eagle, large exhibitions and prestigious dining experiences of up to 1000pax.
Urban Rec is Canberra's social sports club, a one-stop shop for all things sport, and recreation in this city. We are looking for hosts for our Basketball leagues (Thursdays in Braddon starting ASAP new leagues on Weeknights starting in May, June and July).
The Competition & Club Development Manager is responsible for the professional administration and day-to-day operations of senior and junior football competitions within the Townsville region.
We are seeking to appoint a committed and enthusiastic Women's Artistic Gymnastics (WAG) coach for our Beyond the Curriculum (Extra-Curricular) department at St Catherine's School, Waverley. You must be available at least two of the following afternoons Tuesday, Wednesday and Friday.
Race day customer service work for the 2019 Melbourne Cup Carnival. We need the right team to deliver the best ever racing, fashion and entertainment.
To successfully coordinate community Rugby competitions including competition management, administration and match official management.
Horizons is seeking an individual to assist in the efficient organisation and delivery of logistics of tours organised by Horizons. The Company is seeking a talented individual with good attention to detail and organisation skills and a passion for sport and travel.
Permanent Part Time Sport Assistant position available at Leading Independent School. Coordination and administration of the co-curricular sports program (people and logistics), PLUS overall ownership / coordination of 1-2 of the sports within the program.
Strategic leadership role delivering meaningful change to an industry whilst growing and redeveloping a longstanding state sport organisation.
Great flexibility, work casual, part-time or full-time, work up to 38 hours per week, depending on your availability. Coach gymnastics, complete some administrative tasks, mentor and coach a team of gymnasts. Assist junior staff and ensure delivery of gymnastics classes to the highest level of excellence.
Urban Rec is Sydney's social sports club, a one-stop shop for all thing sport, and recreation in this city. We are looking for someone to host our Touch Football leagues (Tuesday in Centennial Park and Wednesdays in Camperdown).
Gymnastics NSW, a membership organization with 72,000 members, seeks a Events and Sports Development Officer to work with our team. The successful candidate will have exemplary time management and organizational skills, which are matched by a positive outlook and an affinity toward customer service.
Sydney Olympic Park Sports Venues is seeking energetic, motivated and enthusiastic venue staff to fill a number of expanding operational positions across its Satellite Sports Venues based at the Sydney Olympic Park Archery Centre. A great attitude will be valued more than just experience.
Working directly with the Barça Academy Technical Directors and the Sydney & Brisbane Academy Managers, the Operations Manager will play a pivotal role in the delivery of the Academy programs, Camps and Tournaments.


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Hughes Architects managing director, Doug Hughes, has praised the work of a partnership between the public, third and private sector that he says has helped develop and drive forward the economic and social growth of the county.
Read More »
It's great to see work starting on the new Palliative Care Unit at Llanidloes War Memorial Hospital in Powys. The local community wanted a unit for patients to stay at in the town - close to their homes - during their palliative care.
Pupils at a north Powys primary school have received a brand new football strip, thanks to a local architects practice.
Plans for 250 new council homes in Powys over the next five years are just the start of a much needed investment in the area's social housing sector, according to a local architect. Powys County Council has announced it will build the homes as part of a five-year programme, adding to the 5,300 homes it already provides in the county.
Plans put forward by Hughes Architects for 96 new homes at Llanidloes, Powys have been approved by councillors. Powys County Council's planning committee approved outline planning permission for the development of land at Bryn Ddu Road for the new development adjacent to the existing Dolgwenith and Tan-y-Bryn housing estates.
There's nothing more satisfying than seeing a job we were involved in right at the start coming through to completion and into use. One such project has been the £7.5million Llys Glan-yr-Afon social care housing scheme in Newtown, Powys.
Young carers from throughout Wales, the Midlands and North West of England are benefiting from a new respite home in north Powys with help from a local architects practice.
Hughes Architects has begun a pre-plann
Plans are to be submitted to develop Welshpool's former social club site into affordable homes for rent.
Nurturing future talent is important in all parts of life and work. None more so than in architecture and building design.
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We approach each job differently, and treat all clients as individuals and every building as a one‑off.
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We work hard to deliver excellent customer service, standing shoulder-to-shoulder with our clients throughout the whole process.


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sælge som varme kager Betty Bee's Attitude 9781490877785
Tilgængelighed: På lager
Betty Bee makes her home in sunny meadows of black-eyed susans and daisiesnot too far from the clear blue pond and frogs with the lazies. Betty is filled with joy, love, and kindness and lots of gratitude. Betty has the perfect Bee Attitude. She considers this special Bee Attitude a gift from God above. She is ever mindful of those around her who need some extra love. Follow Betty Bee as she encourages those she meets along the way and how they too can have a Bee Attitude and then in turn share that with others. In this first book in a series of eight, Betty Bee encounters three little church miceMortimer, Millie, and Maudewho are poor in spirit. Read along to see what has caused this to happen and if Betty can help them get their spirit back! This is the first book in the Betty Bees Attitude series.
- Sprog:
- Engelsk
- 9781490877785
- Forlag:
- WestBow Press
- Format:
- ePub
- Beskyttelse:
- Udgivet:
- 27. april 2015
sælge som varme kager Betty Bee's Attitude 9781490877785