text:
CoverDrive Updates His Q3 Forecast
It's no secret that one of my favorite Seeking Alpha members is CoverDrive. I appreciate his deep knowledge of the auto industry and enjoy his wry sense of humor.
What I like most, though, is that he systematically compiles data, goes where that data takes him, and is afflicted with few of the cognitive biases that blind many of us.
In early September, CoverDrive shared his tentative earnings forecast for Q3. Laying out his assumptions in an admirably clear fashion, CoverDrive penciled in a GAAP operating loss of $ 543 million.
Eight weeks have passed, Tesla (NASDAQ:TSLA) has revised its sales strategy (with more price cuts and model shifts), and more data has become available. In the spirit of Keynes, when the facts change, CoverDrive changes his forecasts.
As before, CoverDrive assumes that in most respects, Q2 will look exactly like Q3. As before, he sees a 5% increase in SG&A expenses even though Tesla guided for them to remain flat.
And, as before, CoverDrive assumes ZEV credits in Q3 will go to zero, as Tesla will bank the credits instead of selling them.
So, what inputs have changed since the last forecast?
CoverDrive earlier assumed the same number of Q3 Model S and Model X deliveries as Q2 (22,000). However, the significant price cuts since then have prompted him to forecast 14,000 deliveries for the Model S and 12,500 for the Model X.
Yes, 26,500. A new record. And that's not even counting Model 3 deliveries.
CoverDrive earlier forecast a 3% drop in the average sales price. Now, though, with even more aggressive discounting and a continued shift among Model S buyers to the 75kWh models, he assumes the ASP will decrease by 4%.
These changes ripple through the revenue and cost categories. As we head into the home stretch of Q3, here are the revised numbers:
The bottom line, then: A Q3 net loss of $ 492 million, which translates to a GAAP per-share loss of $ 2.98 (and a non-GAAP per-share loss of $ 1.94).
That's a better outcome than CoverDrive saw two months ago, when he forecast $ 543 million in Q3 losses (which translated to a GAAP per-share loss of $ 3.29).
The Analysts Play Catch-Up
Will CoverDrive hit the nail on the head with his EPS estimate?
Surely not. But he will have done far better than most of Tesla's analysts. Their forecasts have been coming down dramatically in recent weeks as they converge with those of CoverDrive.
Interestingly, there is no longer any institutional analyst covering Tesla who forecasts a profit in 2018, never mind 2017, even though only a year ago almost all them saw Tesla becoming profitable next year.
For instance, Goldman Sachs, which last year forecast earnings in 2018 of $ 706 million, now instead sees a 2018 loss of $ 727 million. That's a swing of more than $ 1.4 billion.
Let that sink in a moment. $ 1.4 billion. In just over a year's time, Goldman Sachs (a key Tesla underwriter from the beginning) has massively slashed its forecast of Tesla's prospects.
The bullish Tesla analysts have time after time been wildly optimistic with their forecasts. But even when, as invariably happens, the unfolding of events reveals their expectations to have been exuberantly unrealistic, those analysts remain intensely bullish, with price targets that either hold steady or rise.
(Despair not, Tesla longs. There remains at least one "analyst" who is still forecasting Tesla profitability in 2018. And, for Q3 of this year, that same analyst forecasts Tesla losses as $ 220 million lower than those estimated by CoverDrive.)
The Wild Cards: Regulatory Credits and NCIs
Are there some wild cards here? You bet.
As always, there is the ZEV and other regulatory credit wild card. Last year the ZEV credits totaled $ 215 million and the GHG/CAFE credits (which Elon Musk called "mouse nuts") totaled another $ 87 million. That adds up to $ 302 million for the year, or about $ 76 million per quarter.
Tesla recorded $ 104 million of such revenue in Q2. But CoverDrive assumes zero ZEV and other regulatory credit revenues in Q3. Why? Because of Tesla's history of storing up such credits over several quarters and then concentrating the sales in a single quarter.
It's surely possible, though, that Tesla has sold more regulatory credits in Q3 and thereby reduced the operating loss.
In the opposite direction is the adjustment for "non-controlling interests," which shifts some of SolarCity's losses to third parties. In Q2, the loss shift totaled $ 65 million, and CoverDrive, in what he admits is a moment of agnosticism, assumed the same thing would happen in Q3.
Will that happen? Like CoverDrive, I have no idea. Neither of us paid attention to SolarCity's financial reporting before it was acquired, and both of us find aspects of its accounting utterly inscrutable.
I asked Seeking Alpha Contributor Bill Cunningham, who has spent lots of time puzzling through the SolarCity financials, to weigh in. He believes the loss shifting happens when SolarCity securitizes some of its financial assets, but (much to his credit) acknowledged that he, too, has yet to crack the code of SolarCity's non-controlling interest loss shifting.
All things considered, the safest course is to assume the loss-shifting will keep on keeping on, and that's what CoverDrive has done. But to the extent the shift is less than $ 65 million, Tesla's losses will be correspondingly higher.
What About the Model 3?
How many Model 3s will Tesla deliver? As Bill Maurer reminded us this morning, Tesla's most recent guidance is 1,630 (30 in July, 100 in August, 1,500 in September).
Is Tesla likely to meet this guidance? We can only guess. The early buyers have been Tesla employees or insiders, and their purchases are reportedly subject to non-disclosure agreements. A recent comment by Seeking Alpha member "out for now" details what appear to be concerted efforts by Tesla to keep details of Model 3 problems from being publicly disclosed.
(And, indeed, Model 3 YouTube postings continue to disappear.)
However, the actual number of Model 3 deliveries are of little consequence to CoverDrive's financial estimates, as he assumes the Model 3 deliveries will be, essentially, "income neutral" (that is, all revenues offset by an approximately equal amount of expenses).
The Model 3 Rollout Is Looking Like a Disaster
Even though it's impossible to get official information about the Model 3 rollout, there is a new source of anecdotal data: the web forum of the Model 3 Owners Club.
To date, the highest Model 3 VIN reported by club members is No. 250. The low number suggests Tesla is struggling with this launch, just as it struggled with the launches of the Model S and Model X.
The difficulties should surprise no one. Here's CoverDrive:
I suspect Tesla had to stop the Model 3 production line to address quality issues. It's an unbelievably poor launch for any modern car company. But for a technology company that skips the Beta (Design Validation) phase, it's perfectly understandable.
At the risk of repeating myself, skipping the Beta phase is the most foolhardy thing a car company can possibly do. It's the phase where you discover and address "irreversible corrective action" for all the issues modeling and simulation fail to predict.
At the successful completion of the Beta phase, you can execute a "flawless launch," which is the expectation of every car manufacturer except Tesla. Tesla expects "manufacturing hell." Unbelievable!
There is a vast chasm between Tesla's share price and the company's fundamentals; a vast chasm between the rhetoric and the reality.
As with so many other risks, Tesla's share price does not reflect the very real risk of a botched Model 3 rollout resulting from the decision to foreshorten Beta testing.
Will the market remain supine and satisfied, even with a botched Model 3 rollout? Anton Wahlman recently explored that question.
I don't know the answer. But, I believe, we now have evidence that the Model 3 may be in real trouble. I expect at the next earnings call Musk will do all he can to duck and dodge questions about the exact number of net Model 3 deposits (net of refunds requested but not yet processed).
Is it now safe to short Tesla? No, not quite yet. But the day approaches. In the meantime, proceed with caution.
Let's Remember the Pie in the Face
We all remember the third quarter a year ago. In July, Elon Musk published his famous "pie-in-the-face" memo, urging Tesla employees to strain every nerve so that Tesla could show a profit and embarrass its critics.
And, indeed, in Q3 2016, Tesla achieved a $ 22 million profit on the strength of 24,821 deliveries.
Here we are, a year later. CoverDrive forecasts Tesla will exceed its deliveries from Q3 2016 by 1,500 or so (excluding the Model 3 deliveries). Should we not then expect an even greater profit than $ 22 million?
And yet, instead, Tesla will set a new quarterly record with some half-billion dollars of losses.
Why has this happened? It's happened in part because the Q3 2016 profit was artificial to begin with (achieved by cashing in an impressive stock of hoarded regulatory credits). But there are two larger reasons.
First, weakening demand has compelled Tesla to slash prices and thereby reduce margins.
Second, Tesla car buyers, especially Model S buyers, are increasingly opting for lower price, lower performance versions. Here are charts prepared by CoverDrive illustrating what's happened to Model S purchasing patterns in the first three quarters and what he sees happening in the fourth:
Pie in the face? How about, Pie chart in the face?
Who Killed the S75?
Looking at those pie charts, CoverDrive asks this question, and offers a theory:
Who killed the S75? It's not being killed because it's unpopular like the S40 was. In fact, 30% of Model S orders in Q3 were for S75.
Maybe Tesla feels it can convert potential customers to S75Ds. Or maybe Model 3s are soon to be in ample supply? Whatever the case, Tesla surely would not want to disenfranchise 30% of its customers.
I suspect there's an ulterior motive for killing the S75. I think their CPO and RVG programs are in big, big trouble due to lower residual values. Why would you spend $ 60k on a used car when you could buy a new one for $ 70k and trouser the FIT credit?
By killing the S75, Tesla has essentially just raised residual values by $ 5k. So much of Tesla's business model relies on high residual values. The good news is that the Model S gross margin should improve even if gross profit is reduced through lower sales.
The good news of higher gross margin despite lower gross profit. As I said at the outset, CoverDrive has a wry sense of humor.
Disclosure: I am/we are short TSLA.
I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.
Additional disclosure: I am short TSLA via long-dated options


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Joshua 10:24 New American Standard Bible (NASB)
24 When they brought these kings out to Joshua, Joshua called for all the men of Israel, and said to the chiefs of the men of war who had gone with him, "Come near, put your feet on the necks of these kings." So they came near and put their feet on their necks.
Cross references:
New American Standard Bible (NASB)
Copyright © 1960, 1962, 1963, 1968, 1971, 1972, 1973, 1975, 1977, 1995 by The Lockman Foundation
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subset: commoncrawl


text: Black, black, black is the color of tiffs page of our country's history, and here is a carefully researched and richly detailed expose of how popular fears and shortsighted leadership resulted in the forced evacuation of the West Coast Japanese in 1942 and their internment in the interior, a betrayal of America's traditions and its constitutional guarantees, that even the Supreme Court would not overturn. The authors prefer to bring history down to street level, recording individual people's reactions to and experiences of the large-scale upheavals that intruded upon their everyday existences. Thus we get a real sense of how it felt to be a Japanese-American on the streets immediately after Pearl Harbor, what life was like at the assembly and relocation centers. Particular attention is paid to the gap in attitudes and actions between the first-generation Issei and the second-generation Nisei. The book leaves few loose ends hanging, tracing both the earlier origins of anti-Japanese feeling on the West Coast and following up on developments in the Japanese community to the present. This unsavory episode is well worth investigating--""As a departure from American principles that was endorsed by the highest tribunal of the land, it will stand as an aberration and a warning""--but the treatment here may be a bit too thorough for the average reader's taste.


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HEBERPROT-P is a unique Cuban drug for treatment of trophic ulcers both ischemic and neuropathic. It also can be applied when treatment of trophic ulcer complications such as osteomyelitis and gangrene.
HEBERPROT-P has been developing in the capital Center of gene engineering and vascular surgery (Неberbiotec) for about 20 years.
Currently it is widely used in Cuban specialized medical units but it does not go on sale.
In addition, the substance controls the growth of epithelial, endothelial cells and fibroblasts, accelerates proliferative processes in tissues, and stabilizes the motor response of cells as a result of stimuli action.
White lyophilizate for injection solution. 1 vial contains 0.075 mg of Human recombinant epidermal growth factor. Excipients: sucrose 15 mg, dextran 40 5 mg, sodium dihydrogen phosphate dihydrate 1.061 mg, sodium hydrogen phosphate 0.454 mg. The prepared solution makes a clear, colorless, homogeneous liquid without suspended particles.
Method of application of HEBERPROT-P
HEBERPROT-P is applied at the rate of one vial per a patient. The wound surface is cleaned with a sterile physiological solution and dry sterile gauze wipes. The affected area should be measured in cm2. Ten injections per 0,5 ml should be done for treating ulcers with the area of more than 10 cm2. Injections are done in soft tissues, first of all, by needling the wound edges, and then the wound bed of the wound. The depth of needle insertion during injection should be about 0.5 cm.
Competent treatment with the current drug is able to prevent from lower limb amputation. According to the tests made effect from the treatment starts in 2 weeks after beginning of the treatment (injection course).
In accordance with clinic tests ulcers of 50% of patients, who have completed a treatment course with this drug, were completely treated and 70% of patients managed to avoid amputations.
Kiev, Nikolsko-Slobodskaya str., 2-В


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Super Bowl 50 has now come and gone. The Denver Broncos behind a fierce, relentless defense defeated the Carolina Panthers 24-10.
The thought entering the big game on Sunday was that the two-star quarterbacks from each team would lead an offensive barrage against their opposing defenses. With Cam Newton, the newly elected NFL MVP leading Carolina and Peyton Manning the five-time NFL MVP leading Denver, the thought was that offense would dominate.
Nothing could be further from the truth. Both offenses could not accomplish much all game. Denver was able to make just 11 first downs while gaining a total of 194 yards.
That total was the lowest for a winner in any of the previous 49 Super Bowls. For Carolina, Newton completed just 18 of his 44 passes or 44%. Both quarterbacks threw for interceptions and lost fumbles. The two touchdowns by the offenses on the night were from a 1-yard and a 2-yard rush.
C.J. Anderson was the only bright spot on offense for Denver with 90 yards rushing on 23 carries with one touchdown.
Denver was 1 for 14 and Carolina 3 for 15 on third down conversions. The combined percentage ended up at 14%, which was another record for futility in a Super Bowl.
Carolina s Newton summed it up well by saying that both teams dropped passes, committed turnovers, threw bad passes and allowed quarterback sacks.
The Denver defense however was the determining factor. The Broncos forced Newton and his offense into third and long situations.
The game plan worked for Denver, as Charlotte was forced into those situations and could not convert.
A fumble forced by Von Miller early in the first half that was recovered for a Denver touchdown, was an example of what was to follow.
Another season has concluded with Denver as the Super Bowl Champion. Teams will now start preparing for another season that will start in August with preseason and a regular season kickoff in September.
No one is sure if Manning will return next season. The veteran has now won two Super Bowls and 5 MVP of the league awards and the soon to be 40-year does not have anything more to prove.


text:
Migraines with Aura
AyYiYikes, in Migraines and Other Headaches - Not Tonight, Dear
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- I cant keep my levels in a normal range at 1200mg they are too low @ .6 and at 1500 mg they are too high @ 1.2
After a month of trying really hard to be medication compliant and stay on lithium I begged my PDOC to switch me. She finally agreed today. I was hoping to get opinions on medications that have been the most effective at managing your Bipolar. If you have any info on lamictal I'd really appreciate it.


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International Game Fish Tournament Observers (IGFTO) is a federally tax-exempt charitable organziation under section 501(c)(3) of the Internal Revenue Code and is registered with the State of Rhode Island and Providence Plantations as a Domestic Non-Profit Corporation.
P.O. Box 7333
Gainesville, GA 30504-0017
Saturday, November 9, 2019
Delray Beach, FL
Saturday, January 25, 2020
Delray Beach, FL
Tuesday, February 18, 2020
Marina Pez Vela, Quepos, C.R.


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Last update: Mar 01, 2019
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Quote, unquote: just-food's week in words
By Hannah Abdulla | 26 August 2014
Lindt will try again to push up prices next year amid continued pressure on raw material costs.
This week, Russia eased off on its Western import ban, announcing a list of products it would allow into the country. Elsewhere, the takeover battle for Chiquita Brands International took a new twist when juice maker Cutrale Group called on the produce giant's shareholders to vote against its planned merger with Fyffes. Meanwhile, German food giant Dr Oetker struck a deal to buy McCain Foods' North American pizza business. Here is the week in quotes.
"The volume of additional support needed to substitute for the embargoed items in full – if we are talking about short-term, through the end of the year – is tens of billions of rubles. Next year and in the subsequent years, you could say that this sum will be measured in the hundreds of billions of rubles" - Russian minister of agriculture Nikolai Fyodorov says the ban Russia has set on imports is likely to cost more than it has set aside in subsidies.
"Cutrale-Safra remains confident that the Cutrale-Safra proposal offers compelling and more certain value for Chiquita shareholders as compared with the proposed Fyffes combination, and we believe it is evident that Chiquita's shareholders recognise this as well" - Cutrale Group and Safra Group appeal to Chiquita's shareholders to vote against the merger with Fyffes.
"TA understands growth company investing and we believe they can add significant value and resources to our business. TA will help us further solidify and build on our strong foundation" - CEO of popcorn maker Skinnypop, Andy Friedman, announces the investment from private-equity firm TA Associates in the firm.
"We believe that fiscal 2015 earnings will be influenced by consumer sentiment in this slow-growth economy, our continuing investment in and success with new products, higher-trending freight costs and the completion of our dressing capacity expansion project that should also provide efficiency gains" - Lancaster Colony CEO, John Gerlach Jr comments on the annual results at the firm which saw sales increase but profits drop.
"The business suits us and our strategic goal of market leadership in the Canadian frozen pizza market" - Dr Oetker chairman Richard Oetker comments on the acquisition of McCain North America's pizza arm.
"The success of our initiatives to drive profitable sales growth through distribution gains, strategic brand investments, new product innovation and accretive strategic acquisitions in complementary growth categories and geographies has positioned the company with a solid foundation to capitalise on the tremendous opportunities in front of us" - Hain Celestial president and CEO Irwin Simon comments on the full year results which saw profits and sales increase.
"All companies will have to move and will have to explain to trade and consumers that, with that pressure on raw materials, there must be some adjustments in 2015" - Lindt & Sprungli CFO Dr Dieter Weisskopf says Lindt will try again to push up prices next year amid continued pressure on raw material costs.
"Heinz apologises to our consumers in China and wishes to assure them that the Company is 100 percent committed to food quality and safety on behalf of our consumers in China and around the world" - Heinz recalls a batch of infant food in China after officials found it contained lead in excess of the allowable limit.
"We expect the authorities to act. We never contemplated scaling down or shutting down" - Nestle Zimbabwe chairman Kumbirai Katsande comments on speculation Nestle is withdrawing from the country after facing unfair competition from cheap imports.
"Our board reviewed, with our advisors, all aspects of Dollar General's proposal and unanimously concluded that it is not reasonably likely to be completed on the terms proposed. Accordingly, our board rejects Dollar General's proposal and reaffirms its support for the pending merger with Dollar Tree" - Family Dollar CEO Howard Levine says the firm rejects a takeover bid from rival Dollar General.
Sectors: Advertising & labelling, Baby food, Bakery, Canned food, Cereal, Chilled foods, Commodities & ingredients, Condiments, dressings & sauces, Confectionery, Dairy, Dried foods, Emerging markets, Financials, Food safety, Free-from, Fresh produce, Frozen, Health & wellness, Ice cream, Meat, poultry & eggs, Mergers & acquisitions, Multichannel, Natural & organic, NPD & innovation, Private label, Retailers, Seafood, Snacks, Sustainability & the environment, World foods
Companies: Chiquita Brands International, Hain Celestial, Nestle, McCain Foods, Fyffes, Lancaster Colony, Dr. Oetker, Family Dollar Stores, Dollar General, Lindt & Sprungli, Heinz
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- Global Soymilk & Soy Drinks (Dairy & Soy Food) Market - Outlook to 2022: Market Size, Growth and Forecast Analytics


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CBD Water Might Just Be the Next Big Thing Since White Claw
Sparkling water that comes in different flavors are a big hit this month, and it was only a few weeks ago when White Claw suffered shortage nationwide due to its rising popularity.
Recently, a new kind of sparkling water is starting to make rounds on the internet because of its one ingredient that produces a good feeling once you consume it—CBD.
Cannabidiol, or CBD as it is more commonly known, is being infused in plenty of consumer products like cosmetics, coffee, beer, edibles, and tinctures. Companies are looking to expand to a bigger market by targeting bubble water production with the CBD twist, which offers relaxation effects.
These CBD-infused flavored seltzers are a great alternative to the hard seltzers and are quickly becoming a sensation in the market across the country. Some big distributors of beverages are quickly catching on the trend as well.
However, not everyone knows what CBD is, let alone why it's growing famous these days. Does it cause the same high as its cousin product, marijuana? Why are CBD-laced refreshments manufactured and where to get them? Here are some of the things you need to know about CBD water.
Is CBD Illegal?
The Farm Bill of 2018 has given licenses to many growers across the US to cultivate and sell hemp and hemp products such as CBD. However, state and federal laws often don't blend together, causing confusion in many states, particularly those that still have stringent regulations on cannabis.
Hemp is legal under federal laws as long as it has no more than 0.3% THC content. Tetrahydrocannabinol or THC is the active component of marijuana that causes its psychoactive properties.
While hemp and its derivative CBD is lawful in the federal point of view, state laws might still make these products illegal on a certain state, which is also the reason why CBD-containing sparkling drinks may not be legal in all of the US.
Robertson Allen, Ph.D., The Hartman Group senior consultant, advises companies that while CBD is viewed as legal nationwide, infusing it in drinks and food is another regulatory issue that falls under the jurisdiction of the FDA.
Soda-making company Sprig CEO Michael Lewis stated that the FDA stance on CBD is clear, which means that the substance is still now allowed to be incorporated in food and drinks today. It's contradictory to the federal ruling, which is why the FDA is meeting pressure from both Congress and the general public.
Lewis also said that the FDA may likely allow CBD in consumable products anytime now or until 2020.
Why are Companies still pushing for CBD drinks?
Despite the FDA stance, companies are still interested in considering CBD as their next investment. This is because CBD is claimed to have therapeutic benefits, from pain relief to reduction of anxiety. It could be the next popular product especially for young people who are mostly suffering from anxiety.
Allen revealed that their latest study concerning health and wellness showed that consumers are trying out products that may manage or treat their anxiety. CBD-infused drinks might pique the interest of millennials and the Gen-Z since they are also curious about cannabis.
Benjamin Witte, CEO, and founder of the Recess brand attests to CBD's effects because he has used it himself. He recalls trying CBD oil around two years back to tone down his anxiety and hyper personality.
Witte also notes how important it is to build a strong impact when establishing a beverage company. Like Mountain Dew and Sprite that advertise a dramatic change like becoming an athlete, the mood-altering effects of CBD can be a positive addition to the marketing strategy.
Another CBD sparkling water manufacturer from Colorado, DRAM Apothecary, incorporates more than the hemp extract since many plants also have great benefits to health.
CBD affects people differently, which is why such drinks may have varying degrees of relaxation if any at all. Witte likened it to coffee, wherein other people can't tolerate the drink while some can have as much as four cups before bed.
There still isn't any data on how much manufacturers are cashing in on the CBD water venture, but there are clues to note. Four of DRAM's sparkling water are out of stock, and they have recently partnered with Coors to expand the business.
Where can CBD sparkling water be found?
The FDA decision on CBD might still be unclear, but beverage companies have started to market their respective products, usually through online stores. Others can already be found in convenience shops and groceries.
Allen says their company is selling to retailers who live in states that allow medical and recreational use of the substance.
Here are some of the brands that have CBD sparkling water in the market today:
Sprig is based in Newport Beach, California and produces 0% THC CBD sodas. They use stevia as a sweetener and are promoting cocktail recipes that use their sodas in the mix.
DRAM Apothecary
The said Colorado-based company DRAM markets their CBD-infused Beauty Bubbles mixed with rosewater and hibiscus sparkling water. They sell herbal beverages that come in many flavors.
Another company from Colorado produces sugar-free CBD water and some bite-sized edibles.
Recess is a company from New York with a well-designed brand that makes them an Instagram favorite. Their CBD water is sold in NYC stores as well as in Miami and Southern California.
The present is a brand that is the result of a partnership between hemp manufacturer WAAYB Organics and brewery from Colorado called Left Hand. These also come in many flavors.
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First Legal Harvest Season for Michigan's Thousands of Acres of Hemp
While Michigan's recreational market is nearly shaping up, farmers and processors across the state are busy working with another strain of Cannabis sativa L. for its first legal harvest season.
The 2018 Farm Bill spurred this turn of events following the legalization of industrial hemp. Michigan established a pilot program not long after, wherein registered and licensed 572 growers planned to grow 32,614 acres, with 423 hemp processors at the helm.
After cultivating during spring and summer, many farmers are almost to harvesting their first hemp crop legally.
Hemp in Michigan
Vice President Dave Crabill, for the state association comprising farmers, manufacturers, and processors, iHemp Michigan, said that they are looking into scaling hemp to process CBD and the plant fibers.
The group met on Monday in Lansing to discuss hemp's introduction to the agriculture industry in Michigan.
Although the state's Department of Agriculture and Rural Development are still unsure whether the planned acreage has been planted with hemp, Michigan Industrial Hemp Program Director Gina Alessandri stated that the prospective yield at the end of the year determines what kind of the first crop will be produced.
David Connor planted 26 acres of hemp to replace his blueberry farm in Paw Paw. He has since harvested 20K pounds of industrial hemp. The said crop is split between the stalk, which is commonly used for fabric, paper, and building materials, and the flower from which CBD can be extracted.
Connor noted that the ROI for hemp shows promise. According to USDA, an acre of corn is valued at $543, while an acre of hemp can go as high as $10K to $20K. However, Connor said that the process is labor-intensive, and the market value is still a big question since harvest season is still ongoing.
Hemp and CBD
Hemp is a cannabis plant, as is marijuana; however, hemp contains significantly lower amounts of THC or tetrahydrocannabinol, which is the psychoactive compound causing the addictive nature of marijuana. It is a controlled substance since 1970 and is illegal for recreational use based on federal laws.
There wasn't any difference in the definition of both varieties up until the 2018 Farm Bill, which legalized hemp for cultivation and processing. Moreover, the bill permits the transportation of hemp and its related products across different states, provided that the THC content is less than 0.3%.
There are many CBD products in the market today, ranging from a variety of industries, from skincare to pet health and even food tech.
CBD is famous for supposedly having therapeutic benefits, such as to provide pain relief and alleviate anxiety. In 2023, the Brightfield Group forecast study projects the CBD industry to grow at $22B.
How it helps farmers
GTF Llc. CEO Gary Schuler noted that farmers benefit significantly from choosing hemp as their crop because the entire plant can be processed and used. His firm dries and then processes hemp waste to be used in food products, biodegradable plastic, animal feeds, and building materials.
Schuler further added that growing hemp decreases carbon footprint because hemp-based plastics are biodegradable, as opposed to petroleum-based plastics.
While waiting for the Food and Drug Administration to layout the final rules for CBD, Michigan plans to proceed with the hemp program in 2020. They are looking to hand out licenses to interested parties.
On the other hand, recreational marijuana use is another emerging cannabis business that will commence after business license applications on November 1 will be accepted and evaluated before awarding licenses at the end of 2019.
Pilot CBD Store Opens Its Doors to Dawson County Residents
Your CBD Store Dawsonville became the first-ever store in Dawson County to sell CBD-containing products when it opened last Friday, September 20. The store put various CBD products on display like oils, tinctures, topical creams, and water solubles, which they promise are some of the best in the market today.
Offering CBD Products to the Public
Jaime Buice, Your CBD Store general manager, stated that the incidence of getting high from their various products is highly unlikely. He reiterated that their products do not possess any psychoactive property and thus does not cause an addicting high.
He further said that customers come to their store to seek help for many different health conditions. Whether it is to focus more like in attention-deficit/hyperactivity disorder (ADHD) or attention deficit disorder (ADD), or problems in arthritis or inflammation, people are always looking for a cure to their problems.
The store sells various products like water-soluble CBD oil taken with water, topical creams for inflammation and pain, and tinctures applied by placing a few drops under a user's tongue.
More About CBD
CBD or cannabidiol, for all its fame, is still misconceived by many individuals today. It is an active compound in the hemp variety of Cannabis sativa L., the same source plant species as marijuana, an addictive and still largely illegal substance.
This simple fact is the reason for the confusion between CBD extracted from industrial hemp and those that are from marijuana.
Industrial hemp is taxonomically similar to marijuana, yet different in a major way. Hemp only has less than 0.3% of tetrahydrocannabinol or THC by dry weight. THC is the culprit for marijuana's psychotropic properties, which causes the "high" commonly experienced by a marijuana user.
On the other hand, marijuana contains a high THC level of 5-20% by dry weight.
Most CBD oils are produced to have only trace amounts of THC or none of it at all.
It is legal under federal law to sell, produce, and use CBD oil derived from the hemp variety. The 2018 Farm Bill recognizes the lawfulness of hemp and its derived products and is the basis for updates on state laws concerning the said substance.
CBD Laws in Georgia
There are specific circumstances that dictate the state of CBD laws in Georgia, which Your CBD Store Dawsonville and other CBD companies have to respect. For instance, their stipulations use the term low-THC oil instead of CBD oil.
Haleigh's Hope Act or the House Bill 1 of 2015 permit access to CBD oil for residents who are suffering from severe health conditions like cancer or epilepsy. It also grants universities the privilege to conduct studies on CBD that aim to alleviate child seizure disorders. The condition is that the CBD-containing product must not have more than 5% THC content.
Anyone who wants to purchase low-THC oil in Georgia must have an identification card proving that they are in the registry. Other than epilepsy, CBD is also believed to treat other illnesses such as inflammation, arthritis and even anxiety.
MASS Hemp Coalition Wants Clarification on Hemp Laws
The recent policy announcements and the FDA's sturdy position regarding the legality of CBD products have put hemp farmers in a difficult situation. Massachusetts hemp farmers are now supporting a recent bill regarding the clarification of CBD products sales. They want the state to understand and protect the hemp businesses from falling. CBD stands for cannabidiol, which is extracted from hemp plants. CBD has been labeled as non-psychoactive and is thought to deliver some benefits without causing serious side effects in some patients. CBD containing products are not regulated directly, and they are largely sold online. Retailers carrying these products do not usually get in trouble with local health or police departments.
MDAR on Hemp Regulations
The Massachusetts Department of Agricultural Resources regulates hemp growth throughout the state. They issued guidance which stated that the sale of CBD containing food products, animal feed, and dietary supplements or any products making false therapeutic claims are considered illegal. Mark Cusack, former Marijuana Policy Committee chairman representative issued a bill that declared that CBD containing products should not be considered as adulterants and controlled substances, and should be considered as foods. The bill (HD 4339) would allow CBD products derived from hemp to be sold and also made in Massachusetts. The bill was referred to the House Committee on Rules on Monday.
Policy director of Northeast Organic Farming Association Marty Dagoberto mentioned that this bill is a great starting point to address the issues associated with the guidance published by MDAR. Massachusetts stakeholders, MASS Hemp Coalition and NOFA/Mass chapter could consult together and contribute strong recommendations to support the bill, so that the hemp economy can be protected, thus ensuring the protection of hemp farmers.
Growing Support of The Mass Hemp Coalition
More than 100 farmers are licensed to grow hemp in the state, but only one is responsible for hemp-derived CBD production according to the coalition. Non-profit organizations such as the US Hemp Roundtable support hemp industry at the federal level. They said that Cusack's bill could provide strong hemp and CBD protection, as it reflects some important concepts discussed in the Roundtable's Model State Bill. MASS Hemp Coalition wants to share recommendations with the Cannabis Policy Committee and Cusack directly, but they also aim to seek further protection for small businesses, who largely rely on uncontrolled competition of online sellers and local boards of health.
The aim is to seek stronger protection for state-wide business and retail quickly without damaging the current progress, and the Bill HD 4339 just might be the answer, according to Laura Boehner, co-founder of a CBD company, The Healing Rose in Newburyport. A few of the coalition members are already affected by the laws, thus a community-wide approach is immediately needed to protect local retailers and small businesses.
State Board of Pharmacy Speaks Up
The MDAR guidance originated after the FDA stated that CBD cannot be used in the food and dietary supplements, which was backed by the state Department of Public Health. The Department prohibited sales of CBD oils derived from hemp. However, the coalition is united against the guidance. The Massachusetts Board of Pharmacy issued notes to license holders, advising them to review MDAR and FDA statements and to question agencies about CBD product sales. Hemp seeds, proteins, hemp fiber derived clothing are currently approved for sale throughout the state.
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Prime Minister Imran Khan meets Army Chief General Qamaraja Bajwa
ISLAMABAD: Army Chief General Qamar Javaid Bajwa with Prime Minister Imran Khan met Prime Minister House in which the internal and external situation of the country was discussed.
In the meeting, Pakistan's role was discussed in the Action against the banned organizations under the National Action Plan and the Afghan negotiation process. During the meeting, national security issues, internal and external threats, border situation, India's aggressive behavior and effective response to Pakistan were also discussed.
Also Read:Large scheduling of smuggling mobile phones etc. in the middle auto parts
On this occasion, the Prime Minister said that we want peace, but Indian adventure will be answered completely, operations against banned organizations are doing domestic interests.
The Prime Minister further said that Pakistan wants peace in Afghanistan because stable Afghanistan is essential for the peace of the region.
Also Read:Poland hockey team postponed Pakistan tour in April


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Heart Care Video Library
View the RWJBarnabas Health Cardiac Video Playlist on YouTube!
View the RWJBarnabas Health Cardiac Video Playlist on YouTube!
"The way I was treated, I would do it again," she declares. "For me, that's just how simple a procedure this was. The care I received, not just from Dr. Chakhtoura but from the nurses and technicians, was incredible."
"I knew right away that I was where I needed to be. My experience there was head and shoulders above the care I had received anywhere else."
The people that work there are extremely helpful and care about the patients.
offered at these locations in your neighborhoodView All Locations


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Question about Sony Ericsson K800i Cellular Phone
Posted by Anonymous on
the phone is not blocked but locked to network and requires the input of nck code to remove the lock you try.
<**< enter this text string and it will put you through to a personalized menu i just have network with a locked padlock next to it. its cos of this lock making my phone useless unless i enter the correct nck code.harmfully I can only try 5 times then it will lock me out for ever unless someone can explain how to change my imei number.
i replied to your solution. it can be seen above your one
but thats just the problem I dont want to pay for the code!!!! SODS LAW I KNOW>
So you wish to use your phone on another network ? if so you will need to contact the network your phone is currently with asking them for a subsidy unlock code ( sony erricson call this a network control key ) Wiki ref see http://en.wikipedia.org/wiki/Nck . Usually networks will charge you to get this code . You cannot change your imei as it is unique to each and every phone so dont try to enter a code again before you contact your network .
Posted on Mar 13, 2008
You can try your loal phone repair shop as most of them do unlocking aswell however this will invalidate your warranty and most networks recommend doing this , but to my knowledge there is no way of unlocking a phone without paying for it somehow , but I will have a look round and see if there is anything i can find .
Do you need a p.u.k code ? if so then you will need to contact your network provider and ask request a puk code who will be able to unlock your phone .
or other code can you post more info ?
Posted on Mar 12, 2008
Hi there,
Save hours of searching online or wasting money on unnecessary repairs by talking to a 6YA Expert who can help you resolve this issue over the phone in a minute or two.
Best thing about this new service is that you are never placed on hold and get to talk to real repairmen in the US.
Here's a link to this great service
Good luck!
Posted on Jan 02, 2017
SOURCE: Sony Ericsson K800i Problem
Contact vodafone for the NCK. Explain that you are going abroad and want to use local Pay as you go sims to keep costs down. They may do it for free for you.
By the way.
If there is anyone cloning phones reading this thread then your phone can now be cloned. DO NOT EVER list your IMEI number on an open thread.
Posted on Feb 02, 2008
SOURCE: Sony Ericsson K800i Cellular Phone WITH 3
try www.mobile2mobile.net or take it to a mobile center to have it unlock for a small fee.
Posted on Mar 24, 2008
SOURCE: unlock code with o2 network
I have nokia 6600 hand set .I have been already install Ultra mp3 .at this time permanatly ask serial key.
But i don't have idea for this so plz give me solution.
Posted on Feb 17, 2009
SOURCE: unlocking ericsson w850i or k800i
i want to get the nck code
Posted on Feb 19, 2009
SOURCE: Unlock code for Sony Ericsson K800i
I require an unlock code for a sony ericsson k800i. Can you help please?
Posted on Jun 19, 2009
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Living Room Sectional Couch
per item
This living room furniture collection consists of a simple sectional couch with a trunk style coffee table and home accent pieces to complete the full interior design. All of these items are available for view in the showroom of our Perdido Key furniture store.
Contact De'Cor for more on pricing, options, and availability.


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Bosch Ascenta 24 Inch Dishwasher - Black
Bosch Ascenta 24 Inch Dishwasher - Black
Professional installation available for additional fee. Contact store for details.
Price includes any available discounts
+ Wishlist
- Add to:
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Sold out in your area
This Bosch 24 Inch Dishwasher from RC Willey is so quiet, you may forget they're on.InfoLight projects a red light onto the floor to let you know it's on. Load your dishwasher and continue your after dinner conversations. This dishwasher featuers RackMatic on Upper Rack which gives you 2 Height Adjustments so that you can load your dishwasher your way.
The dishwasher that removes much more than food.
Sometimes you need extra peace of mind that your dishes are fully sanitized. Our dishwashers with the Sanitize option provide you with a thorough, hygienic clean, wash after wash. The Sanitize option can be selected with many programs and increases the rinsing temperatures to 162°F. So you can have peace of mind at the press of a button.
When you don't have a full load of dishes.
Sometimes you can't wait for the dishwasher to be full before you need to clean your dishes. The Half-Load option is the perfect solution for smaller loads. It uses less water to wash fewer dishes, offering you a convenient way to save both time and water. So you can accommodate smaller loads.
Perfect cleaning results without wasting a drop of water.
You shouldn't have to wash your dishes, before washing your dishes. With Bosch PrecisionWash™, simply start your dishwasher and walk away. Advanced sensors screen and detect the soil level of your dishes. And precision spray arms target every dish, glass, and utensil. Leaving you with sparkling clean dishes. So when your dishes are done, so are you.
InfoLight® - one red spot providing information.
A red led spot on the floor updates on whether your fully-integrated dishwasher is still operating or finished already.
Dishwashing like you've never heard before.
Quiet operation is just as important as sparkling clean dishes. That means never having to wait until going to bed to rnu the dishwasher. Our dishwashers with EcoSilence™ motor system deliver high-performance cleaning with low noise emission. Two small brushless motors offer quieter operation than a single large motor, and are held in place by rubber suspenders to minimize vibrations. So your home is as quiet as it is clean.
Half Load Option
This option dramatically reduces cycle time and water consumption when washing small, lightly soiled loads that fill half or less of the dishwasher's capacity.
- 46 dBA- Quietest Dishwasher Brand.
- InfoLight® Beams on Floor to Indicate Dishwasher is Running
- RackMatic® on Upper Rack - 2 Height Adjustments
- 24/7 Overflow Protection System®
- Stainless Steel Tall Tub with Polypropylene
- 14 Place Setting Capacity
- LED Remaining Time Display
- Long Silverware Basket Can be Placed Anywhere in the Dishwasher, Adding Space for Other Items
- 269 kwh/yr - Energy Star®
- Half Load Option for Small Loads
|Bosch Dishwasher
|23.6"W x 22.56"D x 33.9"H
|Shipping Weight
|69 lbs.
|Installation Type
|Number of place settings
|List of programmes
|1 Hour US, Auto US, Power Scrub Plus US, Regular US, Rinse & Hold US
|Cycle Options
|Extra dry, half load, Sanitation
|Silence level (dBA)
|Removable top
|Home Connect
|Color / Material housing
|Tin grey
|Color / Control Panel
|Construction type
|Panel ready
|Not possible
|Drying system
|Inherent heat
|Concealed heating element
|Tub material
|Water Softener
|Glass protection
|Surge-back protect. installed
|Leak protection system
|Aqua Stop
|Watts (W)
|Current (A)
|Length outlet hose (cm)
|230 cm
|Plug type
|fixed connection


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- Jump to
- Annual Art Exhibition
- Recent Gallery
Creativity is not the sole domain of the arts at King Edward VII School the Art Department has the privilege of dealing with an emphasis on the creative development of new ideas and to look afresh at what we normally take for granted. One has to keep in mind that originality also involves reflecting on the ideas of the artists.
The visual arts are art forms which are primarily visual in nature, such as ceramics, drawing, painting, sculpture, printmaking,design, crafts and often modern visual arts (photography, film-making & video) and architecture. We try to prepare our learners for a creative, idea-based career in advertising, film-making, architecture, crafts, design, fashion & video-making to name a few.
Creativity is the key to making sense of all knowledge and the vast amount of information that is part of our lives today, and imagination is the foundation for this creativity. Technique forms an important grounding for this expression: "Technique is what you fall back on when you run out of inspiration." Rudolf Nureyev
The study of Art at King Edward VII School is divided into Arts & Culture in Grades 8 & 9 and Visual Arts studied in Grades 10,11 and 12. The emphasis in Art & Culture is on the Arts such as Dance, Drama, Fine Art & Music. From Grade 10-12 the students are encouraged in the Visual Arts and the learners discover the nature and expressive potential of art practical. For all grades the study of a range of artists' work forms a foundation & widens the students' experience of what creativity entails and offers choices of implementation.
The Visual Arts and Art & Culture Departments have a long and varied history at King Edward VII School. Art Students who attended King Edward VII School include some well known artists such as William Kentridge, Brian Stonehobel ( an industrial designer working on F1 Racing cars), Gregory Kerr, Professor Younge ( Head of Michaelis School of Art in Cape Town). There are more to include in this list of dynamic people in the contemporary Art world such as David Andrew, David Paton & Ulrich Louw who have made successful careers based on Art.
Every year an Annual Art Expo is held at King Edward VII School that reflects and displays the many talented students and their masterpieces of art works.


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About Us
Equality Consulting was set up in Adelaide, South Australia in 2017 with the intention to support organisations in shaping and then accelerating their Diversity & Inclusion goals and strategy. Our services include workshops, project based consulting and speaking engagements.
We help build leaders who can lead effectively and with a sense of inclusivity.
About Sonali D'silva
Equality Consulting was started by Sonali D'silva to take the message of Inclusive Leadership to those who influence business outcomes. As Principal Consultant, she conducts flagship programs and takes up speaking engagements. Read more about Sonali's two decades of global leadership development experience. Click here for Sonali's full profile.


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Show 104: Digestive Health and the Microbiome with Yaakov Levine
Herbal Activism at Home: Power to the Dandelion!
As a kid, I'd played dandelion games with my friends, like blowing her seeds to see how many boyfriends we'd have and rubbing her flowers on the inside of our…
Herbal Garden and Wildcrafting Year
The herbalist garden lives year round. Those of us living in the Willamette Valley are spoiled by a temperate zone with short, mild winters matched with equally short summers. We…
Hawthorn Syrup Recipe
How to Make an Oxymel
Show 83: Herb Lab with Herbal Medicine Experimentation
Show 71: Herb Lab with Kratom and Kratom Salve
Ocular Migraine Formula Remedy
Ocular migraines will ruin your day if left its own devices. It starts around the eye socket and then slowly, painfully take the rest of your body captive. Ocular migraines…
Organic Plant Spray
If you have roses, you have bug problems. Roses must be delicious as it seems that every garden bug has a vested interested in taking at least one bite out…
Show 52: Culinary Herbalism with Leda Hermecz
Show 49: Herb Lab with Body into Balance and Herbal 101
Show 48: Body into Balance with Maria Noël Groves
Herbs for Cold and Flu Season: Class Notes
According to the US Center for Disease Control (CDC), flu and cold season typically covers October through May with its peak somewhere in December to February. In the Pacific Northwest,…
Surviving PMS and Perimenopause: Flooding
This is an abbreviated version of "Menstrual Flooding: Surviving the Deluge." Read the full version at Candace Hunter: The Witch Next Door. Flooding can feel like adding insult to injury.…
Show 44: The Versatile Rose
Show 41: The B Show – A Recap of Show 40 and Herbal 101s
Show 34: Flower Essence Healing with Patti Leahy
Show 33: The Art of Chinese Herbal Formulas
Hawthorn Jelly Recipe
Who says heart-healthy can't be absolutely tasty, too? This simple jelly made with Haws and Chili Peppers is one of our favorites. Sweet and spicy, this is the kind of…


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All steak restaurant
Beef top sirloin steak is sliced across the grain for tenderness, coated in a sweet-and-savory soy sauce marinade, then quickly stir fried with fresh green pepper, onion, and tomatoes.All Restaurants Below is a list of all fast food restaurants of which we have menu prices.MGM Grand boasts a wide selection of restaurants for any Las Vegas palette.
We stopped in for Dinner and enjoyed steak, salad, baked potato and orange roll.Find restaurants near me open now MAP This is a map of restaurants near you that are open now, you can zoom-in to find the nearest locations and click on one of them to see more information about each place.
A traditional steakhouse serving the finest Prime Grade and Canadian AAA steaks for your dining pleasure.Indulge in our signature warm popovers, our acclaimed selection of steaks, fresh seafood, satisfying sides and creative desserts.Menus, Photos, Ratings and Reviews for Steak Restaurants in Montreal - Steak Restaurants Zomato is the best way to discover great places to eat in your city.
All Steak Restaurant - FacebookWe are capable of hosting events up to 400 people depending on the Le Milsa location and availability.View menus, maps, and reviews for popular Steakhouse restaurants in New York, NY.From quick service to fine dining, Bellagio has the best restaurants in Las Vegas.
Enjoy your delectable steak dishes with a side of French fries that can be complemented with beverages like cocktails and wine.
Al's Steak House - Restaurant in Alexandria
APL Restaurant | Steakhouse | Hollywood | Adam Perry Lang
THE Steak House - Circus Circus Hotel & Resort
Las Vegas Restaurants - Bellagio Hotel & Casino
Mastro`s Restaurants | An Unparalleled Dining Experience
Steakhouse Near Me | Groupon
Las Vegas Restaurants - The Mirage
Each restaurant is proudly run by world-class chefs who are as authentic as the cuisine they serve.
Harry's Steak House - blogTO - TorontoView the menu for All American Steakhouse and restaurants in Manassas, VA.
The best steakhouses in New York City Devour porterhouses, sirloins and rib eyes at some of the best steakhouses and steak restaurants in NYC Photograph: Courtesy Peter Luger.Based on ratings and reviews from users from all over the web, this restaurant is a Good Option.
Mr Mikes Steakhouse CasualLas Vegas Restaurants At The Rio Work up an appetite and feast on one of the many tantalizing Las Vegas restaurants at The Rio, where overindulgence is highly encouraged.
Experience casual family-friendly dining in our restaurant, or have a drink in our bar inspired urbanLODGE.
Steak 'n Shake - Wikipedia
Steakhouse Locations - Family Restaurant - Texas RoadhouseRead reviews from All Steak Restaurant at 314 2nd Ave SW in Cullman 35055-4117 from trusted Cullman restaurant reviewers.
Restaurant - The Big Texan Steak RanchView menus, maps, and reviews for popular Steakhouse restaurants in Chicago, IL.
All Restaurants - Fast Food Menu Prices
Steakhouse restaurants and menus in Chicago, IL - Allmenus.com
Best Steakhouses in Montreal, Quebec: Find TripAdvisor traveler reviews of Montreal Steakhouses and search by cuisine, price, location, and more.
Chinese Pepper Steak Recipe - Allrecipes.comSteakhouse Deals: 50 to 90% off deals in Steakhouse near you.Restaurant Description. every year after the Bloomin Festival my family and I eat at the All Steak everything is always wonderful, exceptional service, well trained staff, great atmosphere and you have to love those delightful orange rolls best place to eat in Cullman.
The Best Steak Restaurants in New York - Time Out
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Home » Vintage Magazine Ads » Vintage Movie Ads
Scarce original vintage magazine ad for Disney's Snow White and the Seven Dwarfs. Text reveals that the fairy-tale written by Grimm in just a few pages will now be a full-length animated cartoon by Walt Disney.
Tagline or sample ad copy: The seven dwarfs, for example, are no longer a group of little guys with no names, they emerge as very individual little individuals with separate monikers like "Dopey" and "Grumpy" and "Doc." So it all seems like a merger made in heaven—the Brothers Grimm, and the Studios Disney, and the Dwarfs Seven, in Technicolor!
Publication Year: 1938
Approximate Ad Size (in inches): 9 x 12½
Condition: VG
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Office Space for rent.
Rent 30,000+1000 water charges.
Built area-900 sq.ft and 850 carpet area.
Lift facility are provided.
open parking .
Semi- furnished.
Landmark: Next to Serenity INN.
Facing towards North.
Deposit:10 months (300000).
office is in 1st floor.
'When you call, don't forget to mention that you found this ad on Bittoproperties.com
I do not wish to be contacted by telemarketers or representatives of any other website.
bittoproperties.com only offers an intermediary platform to facilitate the transactions between Seller and Customer/Buyer/User and is not and cannot be a party to control in any manner any transactions between the Seller and the Customer/Buyer/User. bittoproperties.com shall neither be responsible nor liable to mediate or resolve any disputes or disagreements between the Customer/Buyer/User and the Seller. Seller and Customer/Buyer/User shall settle all such disputes without involving bittoproperties.com in any manner.
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|Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults.
|Publication Type
|Journal Article
|Year of Publication
|Kearney MF, Spindler J, Wiegand A, Shao W, Haubrich R, Riddler S, Lalama CM, Hughes MD, Coffin JM, Mellors JW
|PLoS One
|Date Published
|Case-Control Studies, CD4 Lymphocyte Count, Drug Resistance, Viral, Genes, pol, Genetic Variation, HIV Infections, HIV-1, Humans, Polymerase Chain Reaction, Viral Load
BACKGROUND: Identifying pre-ART factors associated with the emergence of HIV-1 drug resistance is critical for optimizing strategies to prevent virologic failure. A previous study reported that lower pre-ART HIV-1 pol diversity was associated with higher risk of virologic failure in HIV-1-infected children. To investigate this association in adults, we measured HIV-1 diversity with deep sequencing in pre-ART samples from adults with well-characterized virologic outcomes in a study (A5142) of initial ART conducted by the AIDS Clinical Trials Group (ACTG).
METHODS: We identified 22 cases in ACTG A5142 who experienced virologic failure with drug resistance mutations in RT and 44 matched controls who did not experience virologic failure. cDNA was synthesized from plasma HIV-1 RNA. Each cDNA molecule was tagged with a unique primer ID and RT codons 41-103 were amplified and deep sequenced. Sequences with the same tag were aligned and a consensus was generated to reduce PCR and sequencing errors. Diversity was calculated by measuring average pairwise distance (APD) of the consensus sequences. An exact conditional logistic regression model with percent APD as the risk factor estimated the odds ratio for VF and the corresponding 95% confidence interval.
RESULTS: Consensus single-genome sequences and diversity estimates of pol were obtained for pre-ART samples from 21 cases and 42 controls. The median (IQR) pre-ART percent APD was 0.71 (0.31-1.13) in cases and 0.58 (0.32-0.94) in controls. A possible trend was found for higher diversity being associated with greater risk of virologic failure in adults (OR = 2.2 per one percent APD increase, 95% CI = [0.8, 7.2]; p = 0.15).
CONCLUSIONS: This study in adults suggests there is a positive association between higher pre-ART pol diversity and the risk of virologic failure in adults rather than an inverse relationship reported in children.
|Alternate Journal
|PLoS ONE
|PubMed ID
|PubMed Central ID
|Grant List
|UM1 AI069494 / AI / NIAID NIH HHS / United States
R35 CA200421 / CA / NCI NIH HHS / United States
UM1 AI068634 / AI / NIAID NIH HHS / United States
UM1 AI106701 / AI / NIAID NIH HHS / United States
UM1AI106701 / NH / NIH HHS / United States
U01 AI068634 / AI / NIAID NIH HHS / United States
UM1 AI068636 / AI / NIAID NIH HHS / United States


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Our unique accounting & consulting services empower shop owners like you in identifying areas of concern, provide insights on how to shift concerns into profits and put your business on the path to continued success for years to come. read more
375 Urbandale Ave. Benton Harbor, MI 49022 Tel: 973-677-3500View company website
SAF has partnered with Harbor Graphics : A Division Of Vomela, consultants and manufacturers of ...
P.O. Box 17099 Lansing, MI 48901 800-748-0517
3408 E. 100 S. LaPorte, IN 46350 866-769-7446
P.O. Box 479 14500 Kinsman Road Burton, OH 44021 440-834-1883
86 Tomlinson Road Unit #B Huntingdon Valley, PA 19006 215-947-2884


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Strada means "street" in Italian. Streets matter to us. They're the fundamental infrastructure of our cities and the core of our civic lives. They're the connections between buildings, people, and public spaces. This is why we're so inspired by them and it's a shared commitment to these values that brought our principals together. Just as people mingle on city streets, our office is a place where we freely exchange ideas, challenging and inspiring one another to create exceptional work.
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Although we work out of two separate offices, we are one team.
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611 William Penn Place
Suite 700
Pittsburgh, PA 15219
p: 412.263.3800
f: 412.471.5704
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325 Chestnut Street
Suite 909
Philadelphia, PA 19106
p: 215.440.0190
f: 215.440.0197
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Primary contact8 Military Road
St. John's, Newfoundland and Labrador
Access to the archives may be made by registration with the church office which is located in Canon Wood Hall. This office is wheelchair accessible.
Parking is available in the parking lot adjacent to Canon Wood Hall accessible from the Military Road entrance. Parking in the church lot is restricted to permit holders, visitors may obtain temporary permits from the church office.


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Aryan Khan making his debut along with his father, 'The Lion King' Shahrukh
King Khan, Shahrukh fans and movie lovers have been eagerly waiting for the news of Aryan Khan's Bollywood debut. Earlier, there is news spread like wildfire as Papa SRK suggested Aryan to assist KJO before B-Town debut.
Now the moment has come finally alongside his father. But this is not sharing space on the screen. Here, this adorable father and son are lending their voices to the most famous characters, the King of Jungle, 'Mufasa' and 'Simba'.
SRK to lend voice for 'Mufasa' whereas Aryan for 'Simba' in Hindi for 'The Lion King'. SRK confirmed this news on father's day during India vs Pakistan world cup match.
Now the entire Twitter is trending with the hashtag 'The Lion King' nationwide.
Disney's The Lion King is releasing in Telugu, Tamil, Hindi, and English on 19th July 2019.
Ready for the match with the spirit of #FathersDay. Go India Go!! pic.twitter.com/o09xLTq5d3— Shah Rukh Khan (@iamsrk) June 16, 2019


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Bengali Translation, Learn BengaliLearn Bengali language. Bengali language software, Bengali language course, Bengali university scholarship and learn Bengali online. Speak Bengali, meet a Bengali with Bengali training.
Sindhi Translation, Learn SindhiLearn Sindhi language. Sindhi language software, Sindhi language course, Sindhi university scholarship and learn Sindhi online. Speak Sindhi, meet a Sindhi with Sindhi training.


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Immunization Schedule, Adults: At least 45,000 adults in the United States die of complications of influenza, pneumococcal infections, and hepatitis B each year. Adults need the following vaccines: chickenpox, hepatitis B, MMR, Td/Tdap, flu, shingles, and pneumococcal.
Rabies is a disease humans may get from being bitten by an animal infected with the rabies virus. Rabies has been recognized for over 4,000 years. Symptoms and signs include fever, chills, pain, itching, muscle spasms, seizures, and coma. Treatment depends upon the species of animal, its behavior, and where you were exposed to the animal.
Immunization Schedule, Adults Topic Guide - Visuals
Slideshows, Pictures, Images, and Quizzes:
Immunization Schedule, Adults Topic Guide - Medications and Vitamins
Zoster Vaccine Live
Herpes zoster is caused by the same virus (varicella) that causes chickenpox in children. When this virus becomes active again in an adult, it can cause her...learn more »


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It's your day, enjoy it!
please wait...
Book this experience! There is only seating for 30 people at each Show Cooking, reserved only for the most interested visitors, who will be able to enjoy, observe and savour the various dishes (entree, starter, first and main course) each one accompained by wines chosen by sommeliers.
This show cooking is in Italian and in German
Online promo price:
80€/person + Garda con Gusto apron and bottle bag
The cost includes:
- reserved place watching the Show Cooking closely and tasting 4 courses cooked by the Chef
- 4 different wines paired by Chef's courses;
- dessert;
- tasting of a grappa with the expert of Istituto Tutela Grappa del Trentino;
- coffee ritual of Omkafè prepared with Chemex;
Included in the price of the Show Cooking is a Garda con Gusto Card.
Garda con Gusto Card includes:
- 1 entrance valid for one person for one day;
- 1 starter to choose from the different proposals of the tasting lounges with 1 bubbles* Ferrari Trentodoc OR 1 tasting of small food suggestions with a paired drink*;
- 1 bottle of Surgiva water 25 cl;
* It is possible to replace alcoholic drinks with Maso Giare apple juice.
After 12.00 am on 31/10/2019 it will be possible to buy tickets for the Cooking Show only at the Palavela ticket office, subject to availability.
Write the security code of the image
price: from € 80,00
Garda con Gusto - Gourmet Experience
Go to the shop
Call us +39 0464 554444
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website https://www.gardacongusto.it/
Any offer of Garda Trentino
Riva del Garda (TN) Largo Medaglie d'oro, 5
Tel: +39 (0464) 554444 - Fax: +39 (0464) 025442
E-mail: firstname.lastname@example.com
PEC: email@example.com
Torbole sul Garda - Nago (TN) Lungolago Conca d'oro, 25
Arco (TN) Viale delle Palme, 1
Registro Imprese Trento, C.F. e P. IVA 01855030225
Cap. Soc. € 499.000,00 I.V. - REA N. 182762
© 2014-2019 Garda Trentino S.p.A.
designed by eTour


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When the canvas is freed from the wall you get what Dona Nelson calls Stand Alone Paintings; double sided paintings that have a lot to share about perspectiveRead More
arcmanoro niles at rachel uffner gallery
Arcmanoro Niles at Rachel Uffner Gallery: "The Area" has been widely reviewed closes on February 25thRead More
Sims gets dissected and DAVE is no longer
The Doreen Garner and Kenya (Robinson) exhibition, White Man on A Pedestal, concluded Sunday evening with CENOTAPHIC, a memorial service for Kenya (Robinson's) #whitemaninmypocket at Pioneer Works in Red Hook, BrooklynRead More
As evidenced in their launch of a new initiative entitled Selections, Elizabeth Dee is wired and live in Harlem. Curated by the puissant Larry Ossei-Mensah, this first installment of the series perfectly examples the aims of the program. Selections Curated by Larry Ossei-Mensah Closes Saturday, Feb 25Read More
George Negroponte latest (re)+work. On view at Anita Rogers Gallery through November 30th
The Architecture of Tomorrow Art and Cultural Journal


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Right Playgroup School for Your Child's Successful Career
The first and most important decision you make for your child is deciding which school you want to send them to. The right decision could pave the way to a life of happy learning, enrollment into a prestigious college and an immensely successful career. The wrong choice, on the other hand, could really upset your child and cause a lot of issues in the future. You must also keep in mind that while most pre-schools prefer kids above two years and nine months of age, but if you feel your child is ready to go, you can contact local schools to see if they are willing to take them.
The Chief Factors to Keep in Mind While Choosing
Relationship between Teacher and Student Is Key
Even beyond the curriculum and facilities available, the fundamental relationship between teacher and child is absolutely vital to his growth and progress as a human being. You must absolutely find a teacher who is enthusiastic, engaged and willing to put in as much effort into caring for your child as she would have for her own. Head over to the pre-school you are considering, and ask to speak to one of their teachers. Have a conversation with the prospective teacher. Any good teacher will take great interest and pride in your child's progress and will go the extra mile to get to know them inside and outside the classroom, from his interests to his emotions. By establishing this bond of trust and admiration, the teachers can accelerate the learning process and keep your child happy and interested.
The World of Words
In the formative or the early years, it is important that your child is surrounded by words. See if there are child-friendly books in the classroom, or if the class visits the library regularly. Good teachers always allocate time for reading and learning with a stress on storytelling to keep them engaged. For pre-school or kindergarten, the teachers must lay the foundation for learning to read and understand words, by teaching new words every day and focusing on syllabication, like 'D makes the 'dah' sound' and then using these sounds in alliterative sentences to focus on usage.
The Essential Steps
You need to be really cautious and extra careful while choosing the right playgroup school for your child. Here are the most effective steps to take toward identifying the right playgroup for your kid.
Step One: Deliberate Over the Basics
There is absolutely no reason to be flabbergasted by the very thought of choosing a good preschool. You simply need to consider if the preschool is good enough for your child and whether it would be fitting perfectly into your normal way of life. You must essentially have answers to the questions like do you want the preschool to be in close vicinity to your home or do you want it to be close to your office or do you want the preschool to provide the necessary childcare services during the morning or in the afternoon or throughout the day both during morning and afternoon. If you are looking for subsidized pre-school programs, then also, you must find out before you consider making your final choice. Once you are clear about the answers to the above questions, you would be able to narrow down the choices to the schools in precise locations and settings of your choice.
Step Two: Understand the Relevant Terms
You must learn and understand all the complex terms related to preschool education. Several parents are at a loss when confronted with terms like Waldorf Approach, Montessori Approach, child-centered or faith-based. Before you start researching, understand these concepts clearly as that will help you in making the right choice.
Step Three: Do Ample Research
Once you are equipped with the knowledge of the exact kind of philosophy that would be suitable for your child and if you know the locality you would prefer for your child's school to be in, it would be really easy for you to do the required research work. The best way to do research is to reach out to some other parents. Look for their valued recommendations. Talk to your neighbors, friends, acquaintances, including your pediatrician or your older kid's teacher. Another effective way of identifying a good school would be by browsing through the Internet. You could come across an active playgroup networking community, a fabulous place for tapping into some worthwhile advice and resources.
Step Four: Schedule a Visit
By this time, you have been successful in narrowing down your options and have come up with a couple of settings you seem to be genuinely interested in. Now is the right time to schedule a visit to each setting without losing out any more time. You could at once, understand how things work in a particular preschool by the way the school authorities react to your introductory visits. During your visit, you would automatically be observing if you are given a warm welcome or not. Make sure that the overall ambiance is warm and welcoming and that your child is showing a lot of interest in the things that are being offered here. You must essentially observe how the teachers and other staff interact with the children. Make sure that your child is spontaneously happy in the setting. Make sure that the setting is safe and adequately clean.
The entire choosing process seems like a daunting task, but it really doesn't have to be such an overwhelming exercise. Do your research beforehand, so you can go into the entire process as an informed, aware and curious parent. Ask the right questions, and you'll soon be finding it very easy to compare, contrast and make an informed decision which will be best for your child.
Author Bio: Andrew Thompson is an educator working in an administrative role in one of thetop pre-schools in the country. He has been in the field for nearly a decade and is extremelypassionate about teaching and caring for children. He has recently taken to blogging and he writes about the schooling system, how to choose the right school etc. and also shares useful resources like https://mindseed.in/.


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This is an expanded tuning kit for all AEON headphones. The kit includes Black Foam, Black Felt, 1 and 2-Notch White Felt filters to tailor the sound of your AEONs to your taste.
About MrSpeakers Headphones
Founded by audio engineer Dan Clark in San Diego, MrSpeakers is crafting some of the world's finest headphones with precision and style. In additional to their well-known lineup of planar-magnetic headphones like the Ether and Aeon lines, MrSpeakers recently joined the exclusive club of companies producing electrostatics with their flagship Voce headphone.
MrSpeakers headphones are all hand-assembled in the USA, and their intensive sound research has resulted in a number of patents for technologies like their V-planar driver and TrueFlow magnet array. MrSpeakers headphones are all tuned by Clark, who favors a signature quite close to the Harman Response Curve, that tends to results in a smooth, powerful sound.


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Robbie has been contributing to the blading scene a lot in the past few years with his recent move from Melbourne to Los Angeles. He shares funny stories about running into the locals in NYC, how his fashion style affects him and his blading, as well as the influences that got him there.Read More
Gav is a powerhouse out of Melbourne, Australia following in the footsteps of legends like Blake Dennis, Scott Crawford, and Matt Salerno. We dig into his time skating in Burma, his experience winning the 2017 Blading Cup, the pro skate offer from Roces, and much more!Read More


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Since 2016 the Liberation Institute has been operating on a volunteer basis.
Most of the 2.5 million people incarcerated in the United States will one day be released. In addition to housing and employment, these men and women need to be embraced by a supportive and welcoming community. We hope that the Liberation Institute can provide such fellowship. Our recent graduates are, in many respects, unrecognizable from the men we first met four years ago. We have run on a volunteer and pro bono basis theSE last four years. Now we are looking to raise funds tO lay the groundwork for a robust array of re-entry services.
It is in the spirit of service that we ask that you consider donating to our tax deductible cause. Any contribution will help make a difference. The Liberation Institute is a federal and state registered 501c3 non-profit. All donations are fully tax deductible as allowed by law. Our non-profit EIN is 82-0981918. YOU CAN Check out our profile listing on the Guidestar website.
Sincerely, The LI Team & Co-founders-
Piers Kaniuka, Jessica Kaniuka, and Kevin MartiN
Get in touch today.


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Cortex is an enterprise social media marketing platform that is powered by machine learning and artificial intelligence (AI) to help marketers maximize ROI from their content marketing efforts through more engaging content. The solution serves multi-brand B2C companies within industries such as CPG, food and beverage, and travel and hospitality by building custom content calendars and briefs for upcoming months, and automatically populating them with content for human approval and scheduling.
Cortex helps organizations understand which images, videos, and text will drive consumers to react and engage with their content through the machine learning engine which finds patterns across a database of over 33,000 brands and over 1 billion pieces of marketing content. Users are able to produce social media content that is optimized for a specific audience based on artificial intelligence data, and deploy it at optimal times in order to achieve the highest possible engagement level. Tools for competitor tracking allow organizations to benchmark their posts against the industry and competitors, and get alerts any time a post goes viral.
Cortex's foresight platform tells users which photos, keywords, hashtags, and colors are inclined to inspire their audience, and automatically schedules posts for the best time to reach them. Instant reporting allows users to track key metrics such as followers, engagements, and live industry rankings, and offers actionable insights for Facebook, Instagram, Twitter, and Pinterest all in one place. Users can also track custom content themes and view a centralized history of social media KPI. Cortex allows organizations to manage just a few profiles, or an entire fleet of accounts from a single dashboard.
Strategic recommendations, optimized social platform posting times, detailed analytics, hashtag recommendations, content recommendations, posting capabilities.
Cortex provides strategic recommendations for our hashtag usage and posting times that would take a human much longer to develop. Being able to see our client's entire portfolio within Cortex makes it easy to compare and draw conclusions rather than individual data outputs. Being able to compare our numbers against our competitors and the industry allows for insights that you can't get anywhere else. Our team also loves being able to schedule their content, with direction from the software, and have it automatically post at the scheduled time.
We're looking forward to any new features that will be released. It would be nice to see the "eng rate" in the history table view.
Instead of time-wasting A-B testing, without being able to determine which variable drives engagement, we now use the Cortex foresight platform. Since then we had more time to concentrate on what truly matters.
The result is an increase of up to 275% in organic leads with one of our clients.
Since using Cortex, we have completely changed our content creation process. It used to be try and error. But no it feels like having a full fletched data analyst working for us 24/7. We now know what pictures to take, which hashtag to use and which products to promote at any given time.
Would be awesome to have a mobile version of Cortex, so we never miss a thing when we are on the road. But I'm sure there is already something in development.
Cortex is super simple to use with the interface very friendly.
The ability to review your own social channels against key competitors or pages of interest helps us to continuously improve our content.
The team are super helpful too and developed new functionality just for us which is incredible service.
Our particular usage of social media where we are always posting to social live with breaking news stories meant we didn't take full advantage of the whole functionality Cortex offers.
I love how fast and efficient this product works, as well as the market trends it finds. In todays workplace speed is everything; with Cortex, speed and top quality work are standard
With a company this big, that caters to so many people and businesses, many dont have quite the customer support. Cortex' website shows that they deal with Maroon 5 and Jack Daniels, its one of the reasons why we chose to go with Cortex. But with those major clients, I expected customer service to be better
Contact Cortex for detailed pricing information.
Below are some frequently asked questions for Cortex.
Cortex offers the following pricing plans:
Pricing model: Subscription
Free Trial: Not Available
Contact Cortex for detailed pricing information.
Cortex offers the following features:
Cortex has the following typical customers:
Large Enterprises, Mid Size Business
Cortex supports the following languages:
Cortex has the following pricing plans:
We do not have any information about what devices Cortex supports
Cortex integrates with the following applications:
Facebook, Instagram, Tableau, Twitter
Cortex offers the following support options:
Online Support, Phone Support


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Happy Indonesia Independence Day, to everyone celebrating today! 🇮🇩🇬🇧
Happy Indonesia Independence Day, to everyone celebrating today! 🇮🇩🇬🇧
https://youtu.be/OiSMkWKlKEY A short video overview of our event, "A Peaceful Dialogue with Governor Ridwan Kamil of West Java, Indonesia" held in Manchester on 23rd July 2019, jointly organised by The Association of British Muslims and British Institute of Peace.
Selamat Hari Ibu to all the mothers in Indonesia.
What is a Saint? An excerpt from the amazing film Rahmat Islam Nusantara (The Divine Grace of East Indies Islam) that explains the origins and theology of Islam in Indonesia https://youtu.be/uqDj794wZNw