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Worldwide Enterprise College Suzhou
The definition of International commerce isn't in any respect in contrast to how we might normally outline home commerce. The Worldwide Business profile is extremely related to students who take into account a profession in multinational corporations, international organisations or smaller corporations whose activities involve a considerable diploma of international enterprise. Lecturers with a various and worldwide background, as well as visiting lecturers from partner universities and enterprise schools overseas, be sure that the instructing is state of the art.
Present courses that will qualify for this focus embody: MKT 302 Service Marketing, MKT 305 Market and Advertising Research, MKT 320 Built-in Advertising and marketing Communications, MKT 330 International Marketing, MKT 340 e-Advertising, MKT 350 Advertising for Not for Revenue Organizations.
Worldwide Enterprise Relations majors can select positions at international and multilateral corporations, in ministries of overseas affairs, non-governmental organizations (NGOs), non-revenue associations, worldwide foundations or in humanitarian businesses.
It's …


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Supernatural: The Complete Third Season
Supernatural: The Complete Third Season
The yellow-eyed demon is vanquished, but at a terrible price. The battle that brought him down released hundreds of demons from Hell into an unsuspecting world. And it cost Sam his life. But a grief-stricken Dean made a deal with the Crossroad Demon his soul for Sam's resurrection. Now Dean has just one year to live. One year to fight the unholy, the twisted, the ghoulish. One year to say farewell to Sam. And one year for Sam to search desperately for some way to save his brother. Mind-bending adventure awaits as the Winchester brothers continue their astonishing odyssey into the supernatural...and their personal odyssey into destiny.
- Additional Information
Additional Information
Release Date Sep 2, 2008 Actors Jared Padalecki, Jensen Ackles Runtime 720 Screen Format Widescreen Sound English Dolby Digital 5.1 Special Feature Gag Reel; All-New Featurettes; Commentaries And A Bonus Digital Copy Of The Entire Season! Sub Titles English, Spanish, French, Portuguese Video Aspect 1.78:1
- Reviews

subset: commoncrawl


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Ruffa Gutierrez may be a celebrity but she's just like any proud momma when it comes to her daughters.
The actress just got emotional as she revealed that her eldest daughter, Lorin, is set to go to college abroad.
The 15-year-old is currently in the United States for a pre-college course to study Economics at her dream school, the University of California Los Angeles (UCLA). Lorin will be away from home for three weeks.
Ruffa went on to social media to post throwback photos of Lorin; wondering how time had flown so fast.
She wrote on Instagram, "This little girl I carried while I was pregnant with [Venice, Lorin's sibling] is off on her own this summer as she expands her knowledge at one of the top-ranked economics institutes in the world."
Ruffa has nothing but good wishes for her daughter. She added, "Lorin, spread your wings and embrace this new journey! I love you."
Meanwhile, Lorin revealed her mother was both "happy and nervous" about her living on her own for a while. Lorin said living away from her home as a 15-year-old can be daunting but her mom has prepared her.
She told Cornerstone Entertainment, "I'll be staying in a dorm the whole time and will be cooking, cleaning and doing my own laundry so she made sure I was prepared for all that."
She also added that her mother is really supportive of her decision and also didn't think twice in allowing her.
Lorin said, "She knew that this would be a great opportunity for me and didn't hesitate to allow me. UCLA is my dream university and I hope to study there after high school, but its incredibly hard to get into for actual college so I'm making sure to keep my options open."
She added she'll be back in August and "will resume with life as it is now."
Source :Push


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Update: After writing this I heard from Toki's mom, who had great news! Toki just visited the doctor and it turns out he's doing amazing and isn't going to have to have that last surgery after all! He's only wearing a brace at night and that gets to go off in three weeks. What an incredible journey coming to an end. Thanks for the great update!
Earlier Post:
This photo session was all about Toki. He recently turned one and on top of that major milestone, has come a long way in the last couple of months physically. He has hip dysplasia and in just one year was in and out of three braces, had surgery and a cast. He still has one more surgery to go, but will hopefully be feeling good and ready to take on the world after that!
Back when we first scheduled his session he wasn't even sitting up on his own yet. We actually had had to reschedule that one and another because of bad weather, but the timing worked out perfectly. He's sitting up, crawling, able to stand while holding onto things and even walking with help from mom and dad now.
He's seriously a super happy kid and flashed all sorts of cuteness toward the camera. Between him and his adorable big sister, I was smitten! Their big blue eyes, blonde hair and awesome expressions will make anyone smile.
This is such a lovely family and it was so great to see them all again and how well they're doing! Congrats on one year and even more big steps to come!
Lots of love,


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SIZE: 22x9.5 | 22x10.5
HARDWARE: Exposed
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Exposed Stainless ARP Hardware
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Stay up-to-date with the industry style leader. Latest jaw-dropping builds, trend setting styles, and top events in the industry.
Decades of study and participation in every aspect of the wheel industry has guided us to an intense appreciation of the absolute best craftsmanship, quality, design, engineering, and manufacturing.


text: Overview Itinerary Price ACCOMMODATIONSHotel : Radisson Blu or similar Hotel : Deshadan Mountain Resort or similar Overnight on board the houseboat. Hotel : Lake Song Resort or similar ADDITIONAL REMARKS Tipping to English speaking Station Guide/Driver at USD$6 per day/passenger Monument & Entrance Fee : USD19 (Exclude) Updated : 14Feb2019 English | 中文 Itinerary DAY 1 Arrival Kochi Upon arrival at Kochi International airport you will be met by a representative who will assist with the transfer and check-in at the hotel. Kochi is situated on the south-west coast of the Indian peninsula, in Kerala. Its importance over the centuries as a strategic maritime centre has earned it the name – Queen of the Arabian Sea. Kochi is also called the Gateway to Kerala. In the evening, enjoy an enthralling performance of Kathakali. KATHAKALI: The ancient dance –drama form of Kerala. DAY 2 Kochi/Munnar (130Kms) In the morning, proceed with a tour of Kochi. FORT KOCHI: The Fort Kochi heritage zone (6 km or so) is wonderfully cosmopolitan, with a beautiful cultural mix of Malayali Christians, Hindus, Muslims, and Jews. Fort Kochi is where the influence of the Portuguese, the Dutch, and the British can be seen the most. The area has charming old-world streets and buildings. See the ancient Chinese fishing nets (Cheenavala), distinctly unique to Kochi. It is believed that traders from China introduced these nets here. Remarkably, outside of China, these nets are found only in Kochi! The St. Francis Church is said to be India's oldest European church. It was originally built by Portuguese friars in1503. Vasco da Gama was buried in this church in 1524 before his remains were moved to Portugal. The Dutch Palace (Mattancherry Palace) was built by the Portuguese in 1555 as a gift for the Maharaja of Kochi. In the afternoon drive to Munnar and on arrival check in at the hotel. You have the day at leisure to explore the sights of Munnar. DAY 3 Munnar Journey through Munnar and take in breaths of pure, fresh air; take a short trek;; spot creatures in the wild; go fishing; explore the dam; taste exquisite tea; or simply relax and enjoy the wonderful surroundings. MUNNAR is Kerala's most famous, stunning hill station sits high at 5,000 feet in the Western Ghats mountain ranges, at the confluence of three streams – the Nallthani, the Kundala, and the Muthirapuzha – that make their way out of the hills to join the mighty Periyar River. Munnar gets its name from the words moonu aaru in Malayalam, literally meaning 'three rivers'. Serene blue lakes, cascading streams, roaring waterfalls, emerald forests, a wildlife reserve, endangered animals and birds, tea plantations, a dam – gorgeous Munnar has it all. Once the summer resort of the British in the 19th century, Munnar was perhaps Kerala's best-kept secret till it was happily discovered by nature lovers, wildlife enthusiasts, holiday-goers, and tea-tasters/lovers! Munnar is also known for the rare Neelakurinji flower that blooms only once in twelve years. The 'kurinji season' in Munnar is a magnificent sight when the landscape is covered in a sea of blue! Overnight at Munnar DAY 4 Munnar/ Alleppey (260 Kms) In the morning, check out of your hotel and drive to the spot from where you will board a kettuvallom for a Cruise on the backwaters towards Alleppey. Alleppey is one of the lowest lying areas in India, the Kuttanad region of Kerala is called the rice bowl of the state. Paddy here is actually grown on water-filled fields reclaimed from the sea! Alleppey, with its endless stretches of paddy fields, small streams and canals, bridges, a silver beach, serene lagoons, and emerald coconut palms, lies in Kuttanad. Alleppey's great allure is its stunning backwaters. The town has at least six navigable canals that are its lifeline; connecting the city to the intricate thread of backwater trails, earning it the name "the Venice of the East". Alleppey lies between the Arabian Sea and a vast network of rivers flowing into it, explaining its unique blend of fresh and saltwater eco-systems. A luxurious cruise on a kettuvallom, through the backwaters, is the finest way to experience the natural beauty around you; see lush paddy fields and narrow canals, enjoy panoramic views of lake-side villages as villagers go about their traditional occupations such as fishing and agriculture. DAY 5 Alleppey/Kumarakom (32Kms) After a sumptuous breakfast on board the Houseboat, continue sailing till the jetty point where you would disembark from the houseboat and switch over to your vehicle for a short drive to Kumarakom. Upon arrival check into your hotel. The day is for you to spend at leisure. KUMARAKOM is also called "one of the ten paradises on earth" by National Geographic Traveller, Kumarakom is a stunningly beautiful cluster of backwaters fishing villages set against the backdrop of the Vembanad Lake in Kerala. DAY 6 Kumarakom/Kochin (91Kms) After breakfast, depart for Kochin and check in at the hotel on arrival. Rest of the day is at leisure and free for last minute shopping / souvenir hunting. Overnight is at the hotel DAY 7 Kochin Departure (44Kms) After Breakfast drive to Kochi International Airport to board the flight for onward destination Price Hotel Adult Child Extension TWN SGLCHTCWBCNBTWNSGLCHTCWBCNB + GV2 01Apr2019-31Oct2019S$668S$1018S$668S$668S$498 - - - - - + GV4 01Apr2019-31Oct2019S$568S$918S$568S$568S$398 - - - - - * Price listed is per person Legend


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Duration: 8:00 Views: 134 Submitted: 3 months ago
Description: Leonie-Marie is a presenter for "Love Confessions", a reality tv show. Driven by the need for ratings, Leonie-Marie documents some of the most cynical stories, often violating the privacy of the subjects. So when the opportunity arrives to enter a community practicing free love, she jumps at a chance to film what she sees as doomed menagerie of sex maniacs. But for once, Leonie-Marie's story is not as simple as it seems, and proves to question her own sexuality more than her subjects! Ovidie directs and stars in her outstanding third explicit feature, that again questions the fluidity of sexuality and the reasoning behind monogamy, which she has dubbed "a comedy of morals".
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Though you may not be able to escape the aging process, you can fight back with aesthetic treatments like a PDO threading face-lift. At My Retreat Med Spa in the Greater Atlanta area, the talented team of certified medical aesthetic experts offers an innovative approach to nonsurgical face-lifts with PDO threading to rejuvenate and regenerate your skin in about an hour at the med spa. Learn more about this cutting-edge treatment for a younger, firmer, appearance. Call or book online today.
Polydioxanone (PDO) threading is a nonsurgical face-lift that rejuvenates sagging skin. During this procedure, your experienced medical aesthetics provider injects special surgical-grade threads into areas of your face with a fine needle. The thread is made from polydioxanone — a material that has been used for medical sutures for more than 35 years.
The PDO threads lift your skin tissue and improve its texture. The threads also stimulate the production of new collagen, so your skin continues to become firmer and regenerate new cells and tissue in the weeks following your face-lift. Your body absorbs the threads as they dissolve and eliminates them naturally, so there's no need to return to have them removed.
The minimally invasive PDO threading face-lift involves injecting tiny threads into the deeper layers under the surface of your skin. There is some discomfort during this procedure, but patients usually tolerate it well. You may request a topical numbing cream to help minimize any discomfort.
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The Iraqi Defense Ministry says the second-in-command of the Islamic State (IS) extremist group has been killed in a coalition air strike in the country's north.
Azerbaijan's state-owned oil company SOCAR reportedly spent hundreds of thousands of dollars to secretly bankroll a trip to Baku for 10 members of the U.S. Congress and provide them with gifts.
Authorities in Kazakhstan say they've found hundreds more carcasses of a critically endangered species of antelope in a northern region, with the toll in the latest die-off now topping 1,000 animals.
The United Nations says the death toll from a May 13 Taliban attack on a Kabul guesthouse popular with foreigners has jumped to 14.
Russian says the country's land forces will join troops from Belarus, China, India, and Mongolia in a series of joint military training exercises during the second half of this year.
A Moscow court has turned down a request by Russian prison officials to replace outspoken Kremlin critic Aleksei Navalny's suspended sentence with a prison term.
NATO and Ukraine are calling on Russia to stop its "continued and deliberate destabilization" of eastern Ukraine.
A Russian nationalist biker gang has been awarded a free plot of the land taken from Ukraine.
A lawyer for a man accused of burning a copy of the Koran in Russia says that the suspects in the case are believed to be members of a neo-Nazi group that authorities have blamed for several killings and other crimes against ethnic minorities.
German Chancellor Angela Merkel has said a cease-fire agreement was still being violated in eastern Ukraine on a regular basis.
Ten years after the Andijon massacre in Uzbekistan, rights activists say the regime of Uzbek President Islam Karimov has frightened witnesses into silence -- including those who have sought refuge as exiles abroad.
NATO's Secretary-General Jens Stoltenberg said the alliance and Afghan leaders have agreed on a framework for a future joint military-civilian presence in Afghanistan when the bloc's current mission ends.
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Description : AYTEK is a Producer and DJ based in Pune, India. Starting his career as a producer, he has been actively making music since 11 years and has been hugely popular for his soothing chill out reprises & remakes which have been made to perfection for any music lover.
With support from various international as well as Indian artists Aytek has released multiple singles as well as EP's on Beatport Charts. Influenced by Gareth Emery, Above and Beyond & Armin, the first release was Time is Running out signed by Neo Red Records in 2010. His latest latest release, Aftermorning – Core (Original Mix) released on ShiftAxis records has been in the Beatport Top 100 Progressive House releases.
He performs various styles and genres with a focus on electronic music, including bass-heavy remixes of club and hip hop favourites, commercial as well as amalgamations of other styles.
In an industry that is often more interested in the bottom line than artistic merit, Aytek has manag


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India, US ask Pakistan to act on terror, after foreign secretary Vijay Gokhale's meeting
The two countries had issued a call to Pakistan to undertake "concerted action" to dismantle its terror network after Gokhale called on US secretary of state Michael R Pompeo on Monday.world Updated: Mar 13, 2019 21:05 IST
India and the United States on Tuesday called on Pakistan to "meaningfully address" global concerns on terrorism and cross-border terrorism, during Indian foreign secretary Vijay Gokhale's ongoing trip for diplomatic consultations.
"Both sides called on Pakistan to meaningfully address the concerns of the international community on terrorism, including cross-border terrorism," Indian embassy said in a readout of Gokhale's meeting with his US counterpart, under-secretary for political affairs David Hale.
The two countries had issued a call to Pakistan to undertake "concerted action" to dismantle its terror network after Gokhale called on US secretary of state Michael R Pompeo on Monday. And National Security Adviser John Bolton wrote shortly after on Twitter he had asked Pakistan's foreign minister Shah Mehmood Qureshi to take "meaningful" steps toward combatting terrorism.
Gokhale and Hale also reviewed progress on subjects discussed and agreed upon at the first 2+2 ministerial meeting in New Delhi last September and on how to build on "convergences in the Indo-Pacific and agreed to work with each other and regional partners to promote inclusivity, stability, peace and prosperity in the region".
The foreign secretary is in the US for a round of pre-scheduled diplomatic consultations, which given the context of the Pulwama attack, has seen the two countries to stress counter-terrorism, an issue that is of utmost importance to both, and Pakistan continued support of terrorism as a foreign policy tool.
First Published: Mar 13, 2019 21:05 IST


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CliffsNotes on Dickens' A Tale of Two Cities
The original CliffsNotes study guides offer expert commentary on major themes, plots, characters, literary devices, and historical background. The latest generation of titles in this series also feature glossaries and visual elements that complement the classic, familiar format.
In CliffsNotes on A Tale of Two Cities, you experience one of Charles Dickens's most important works as he recounts the horrors of the French Revolution in what amounts to a cautionary tale warning of the possibility of revolution in 18th-century England. From its first line ("It was the best of times, it was the worst of times") to its last ("It is a far, far better thing that I do, than I have ever done; it is a far, far better rest that I go to than I have ever known"), Dickens's novel of revolution, sacrifice, and redemption continues to captivate modern imaginations.
Chapter summaries and commentaries lead you through Dickens's "Tale," and critical essays give you insight into the women of A Tale of Two Cities and the French Revolution. Other features that help you study include
- Character analyses of the main characters
- A character map that graphically illustrates the relationships among the characters
- A section on the life and background of Charles Dickens
- A review section that tests your knowledge
- A Resource Center full of books, articles, films, and Internet sites
Classic literature or modern-day treasure—you'll understand it all with expert information and insight from CliffsNotes study guides.
Product Details
|Houghton Mifflin Harcourt
|Publication date:
|Cliffs Notes Series
|Sales rank:
|Product dimensions:
|5.25(w) x 8.25(h) x 0.32(d)
About the Author
MARIE KALIL received her M.A. from the University of Nebraska-Lincoln, specializing in nineteenth-century British and American Literature. She has taught at the University of Nebraska at Omaha and Iowa Western Community College.
Table of Contents
Life and Background of the Author.
Introduction to the Novel.
Critical Commentaries.
Book the First: Recalled to Life.
Chapter 1: The Period.
Chapter 2: The Mail.
Chapter 3: The Night Shadows.
Chapter 4: The Preparation.
Chapter 5: The Wine-shop.
Chapter 6: The Shoemaker.
Book the Second: The Golden Thread.
Chapter 1: Five Years Later.
Chapter 2: A Sight.
Chapter 3: A Disappointment.
Chapter 4: Congratulatory.
Chapter 5: The Jackal.
Chapter 6: Hundreds of People.
Chapter 7: Monseigneur in Town.
Chapter 8: Monseigneur in the Country.
Chapter 9: The Gorgon's Head.
Chapter 10: Two Promises.
Chapter 11: A Companion Picture.
Chapter 12: The Fellow of Delicacy.
Chapter 13: The Fellow of No Delicacy.
Chapter 14: The Honest Tradesman.
Chapter 15: Knitting.
Chapter 16: Still Knitting.
Chapter 17: One Night.
Chapter 18: Nine Days.
Chapter 19: An Opinion.
Chapter 20: A Plea.
Chapter 21: Echoing Footsteps.
Chapter 22: The Sea Still Rises.
Chapter 23: Fire Rises.
Chapter 24: Drawn to the Loadstone Rock.
Book the Third: The Track of a Storm.
Chapter 1: In Secret.
Chapter 2: The Grindstone.
Chapter 3: The Shadow.
Chapter 4: Calm in Storm.
Chapter 5: The Wood-Sawyer.
Chapter 6: Triumph.
Chapter 7: A Knock at the Door.
Chapter 8: A Hand at Cards.
Chapter 9: The Game Made.
Chapter 10: The Substance of the Shadow.
Chapter 11: Dusk.
Chapter 12: Darkness.
Chapter 13: Fifty-two.
Chapter 14: The Knitting Done.
Chapter 15: The Footsteps Die Out Forever.
Character Analyses.
Critical Essays.
CliffsNotes Review.
CliffsNotes Resource Center.
Customer Reviews
Average Review


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kiaduran, who was the winning bidder in the Snapdragon auction. Thank you very, very much. Tomorrow, I've been told, Ignatius will be composing a brief letter of introduction on her behalf, which I've been asked to witness and sign. And then Snapdragon will be on her way to you. Spooky's very pleased she's going to a good home.Just a quick entry to congratulate
- Current Location:The Pelennor Fields
- Current Mood: grateful
- Current Music:Poe, "Hey Pretty" (Drive-by remix)
( 1 comment — Have your say! )
( 1 comment — Have your say! )


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Trolls and Warrior King photographers; Newbie photographer survival advice
This is for any photographer that feels brow-beaten by peers or shamed on social media for so called un-originality or just negativity around their photography
We all start somewhere - Every end has a start, every artist went through a stage of un-originality. We've all shot howlers, and we only now know they were 'bad' when we go back and look at our old work. I don't see my previous work in any kind of a shameful way, I see it purely in terms of my personal growth (though I do still cringe at some of my shots!).
In any endeavour, you need to learn the basics, and working out lots of things on the fly is a given. You then forget them, repeat the same mistakes, remember those mistakes; rinse and repeat. And it's those failings that teach us things. Photography is the same as everything else. You think you know everything at first because you are shooting in Portrait mode (the little dial on the top of your camera. Generally it is denoted by a capital 'P'), and you are on the top of the Mountain while you are using it. You are the Warrior King, and your pictures are awesome. You begin to wonder if you are in fact James Bond. You then read about Manual mode. You are awesome, so you put the camera into Manual mode and everything falls apart in your shots. They are blurry, or over exposed, and why is the background so sharp? You now realise you aren't even in the foot hills of those Mountains you just thought you were the King of, and you are in fact just about to click 'buy' on the holiday to those Mountains while sitting typing on your laptop while in your PJs. And make no mistake, it's a daunting journey, but it's worth it to have so much more control of your camera and understand why it does what it does.
All of our journeys are different - As are the people we encounter on that journey. I was bought a camera for my 16th Birthday, couldn't use the damn thing, sold it and bought loads of comics and books and subsequently dedicated my existence to breaking myself into small pieces while doing BMX Freestyle. I of course came back to photography, and it was through my love of Henri Cartier Bresson & Annie Leibovitz's work (I know. Colour me a cliche') that I did. I unashamedly love their work. Simple as that, and through that, many other fabulous photographers.
Surviving online negativity - The difference now is social media. Lots of people are uploading their work on things like Instagram, Facebook, etc and in their fledgling endeavours to show the world what they can do, their view of the world, or how awesome their cats are, are then getting savaged. And is this warranted? No is 99% of the answer. There are always the 1% delusional photographers, but as they are delusional, they won't be reading this! Asking for critique is one thing, and you take it all on the chin, because how else can you grow? But the barrage I see daily of unsolicited criticism is just not helpful in any way, and a lot of the time, it's out and out spiteful but that is now part of the playing field. It of course doesn't have to be. There are loads of supportive photography communities on the web. Truthfully I'd suggest joining some of them, and let you and your art grow up in less savage and destructive environments. The caveat is of course, always know you can always be better, no matter what anyone tells you. Support and encouragement are great, someone fluffing your ego is not. If you are a big fish in a small pool, don't carry that attitude into more advanced groups. I suspect you know what will happen if you do….
So where does it all the negativity come from? Aside from some people having superiority complexes, crappy attitudes, or just want to troll, you don't really need to go too in depth to realise that anonymity on the web can bring out the worst in people, or even if you know who they are, they can't see you for a person as you are just a disembodied profile picture of someone they will never have to look in the eye. Its a failing on their part, not yours. And this brings me to how Photographers can act towards other photographers, because at the heart of it as well as the public they can be a fickle mush heads. We see the same images again and again and we can get jaded. Then ten years later, an Ad agency puts out an advert with a pose or lighting that is no longer in vogue, and then it's 'retro' or 'chic' or any number of adjectives that in truth bore me and we all chuck up our hands in the air like it's something new and then over use it till we are all then sick of it again. So with that in mind some photographers get it into their heads that they are the last bastion of what is good and right in the Kingdom of Photography. And they then decide that they must share their wisdom with you (er, a bit like what I am doing now. We'll just skip that ). The poor photographer who has offended their sensibilities and outraged their Photography chronometer of what should be allowed to be shot in what year is then left thinking 'Wow. So I should be shooting something more modern? More black and white?" You have a ladder in your shot? 'Dude, that so sub 2000' - Beauty shots with a back light and reflector? 'Dude, that's the 90's' (Tell that to Sue Bryce).
You get the idea. And with these people, what do you do? Personally, my advice is to just drive on by. If they are persistent, block them. On your photography journey, they are just stones and pot holes that you can walk around. You don't need them in your life, why bother with them.
What made me write this post? Negativity on social media was a large part of it. In closed groups on forums, Facebook, etc, bashing someone elses photography is still in evidence, and it always will be. It doesn't make it good or right, it simply is, and will not go away. And for some souls that gut punch will leave them reeling and wheezing metaphorically on the floor. They'll drag themselves off the canvas, put up their artistic boxing gloves, and carry on. They are down but not out. But there are also folks who are of a more sensitive disposition, and this blog post is for them. You are not alone. It feels like it, but you aren't. If the negativity is too much somewhere, retreat for a bit. Do your thing. Put your camera down if need be and learn to bake bread, learn to handstand or just go out with your friends. Someone elses view on your work is just that. Their view. It isn't definitive.
So you do your thing and grow. Don't let the bastiches drag you down.
And if you are looking for anything to help you understand basic photography
Scott Kelby (honestly hard to go wrong here for beginners!)
Basics of Digital photography
The Digital Photography Book: Part 1 Part 2 Part 3
Professional Portrait Retouching Techniques for Photographers Using Photoshop (Voices That Matter)
Joe Mcnally
The Moment It Clicks: Photography secrets from one of the world's top shooters (buy from a second hand seller. Much cheaper!)


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A successful swap
Dear Editor:On behalf of the Aspen Ski Swap, I would like to thank everyone involved for our best ski swap ever!The Aspen Ski Swap is a nonprofit, volunteer event that could not take place without the hundreds of volunteers who so graciously donate their time and energy. In addition, we rely heavily on the local media to help promote our event.A special thank you to Catherine Lutz and Damien Williamson at The Aspen Daily News, who gave us front page coverage twice and was an editor's choice for a weekend event. Josh Taylor, Rochelle Obechina and DBach from KSPN, Don Cheney from KSNO, Jim Lawrence, Jeannie Walla and Bonnie Behrend from KUUR, Madeleine Osberger and Robin Morse from The Snowmass Sun, Brad Manosevitz from GrassRoots TV and The Aspen Times.We appreciate the support. This year we had a record number of people shopping and we will be able to donate a record amount of grant money to the Aspen School District. Thank you for your support.We hope to see you at the 53rd Ski Swap on Nov. 2 and 3, 2007.Michael TaylorSki Swap chairmanAspen
Start a dialogue, stay on topic and be civil.
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Working Together for Success
The Key Stage 4 Manager My aim is to help solve any issues that may arise concerning the curriculum. Concerns in lessons Falling behind with work Underachievement Advice on revision strategies Provide support to individuals
Positive Partnerships Research indicates that family involvement in schools increases student achievement (Henderson & Berla, 1994; Ballen & Moles, 1994; Epstein, 1995). It is important to work in partnership to 'get it right for every child'.
Changes to GCSEs All terminal assessment Revision becomes very important Good notes to look back on will be key Mock exam revision much more important Controlled assessment grades crucial Learning/ revising homeworks normal More in class tests
What is Controlled Assessment? Controlled assessment is the internal assessment component of the GCSE courses that is completed in school. It is completed in the classroom so it is supervised, so students are not able to work on it at home. It replaces coursework.
What are the advantages? It allows students to demonstrate their skills in class. A percentage of a GCSE is awarded for controlled assessment. Controlled assessment is carried out IN THE CLASSROOM, so time outside school can be spent preparing for vital examinations and class tests.
Is it for all subjects? No… Maths and Religious Studies GCSEs are courses that are based on examinations only. They include no controlled assessment.
Is it for all subjects? No… BTECs are different: BTEC courses have no examinations, assessment is carried out using a range of assignments, case studies and practical activities. Students complete a portfolio of evidence that shows the work they have completed. Students may work on this outside the classroom.
My Expectations Continue to foster positive relationships. Show resilience – dont give up! Ask for help. Be punctual and improve attendance. Be prepared – equipment / homework Meet deadlines – seek help and dont fall behind.
Students should take responsibility… Some subjects have as much as 60% of their course as controlled assessment, others have only 25%, so attendance is important. Catching up can prove difficult as it must be done in school, extended after school sessions are necessary to facilitate this. (Prep@thepatch)
Attendance & Punctuality Punctuality is also important as it an mean missing registration or assembly, two of the most important parts of the week in making sure you are prepared for learning/ getting the key messages
Journey So far… Progress was judged as good against Key Stage 3 targets. Yr 9 GCSE courses - Philosophy and Ethics 17% A*- A and 51% A* to C grade; But also 24% F-U. Revision skills need to improve for some. In general the attendance could have been much better in Yr9 (90.9%). This is an average of around one day a fortnight off for each student. At KS4, this means missed controlled assessment; missed topics for exams.
Attendance & Punctuality The government says that 95% attendance should be a target for all students. Two days off a month is a 10% learning loss. One day off per week is a 20% learning loss.
Working with the School Check your child is aware of deadlines and is meeting them. Make sure that they are using their planner regularly. Check your child knows when exams, tests or controlled assessments are and that they revise Check they are fully equipped for school Communicate with school if you need to: ring teachers or use the planner Make sure your child is attending fully
Top tips for supporting revising
Hydration Oxygenation Sleep Brain gym Nutrition Music Brain Boosters
Helping with revision
Learning is Emotional Students should make learning colourful, exciting, musical Give students a reason for learning. Set students goals for learning & reward their efforts Revising with music, breaks, food is good!
Some statistics to consider We Remember: 5% of what we read once 20% of what we read a few times 30% of what we hear 40% of what we see 50% of what we say 60% of what we do 90% of what we see, hear, say and do
Record it! Tape the key points, or make a podcast! Use different peoples voices Play it last thing at night - your subconscious will process it whilst you are asleep Most MP3s have a microphone
Flash Cards Posters Revision walls Lists and Notes Fact Sheets A variety of approaches to writing and remembering
One of the most effective ways of learning is to teach someone else – let students explain things to you Test your child – you could build in a testing period each day in the run up to exams Use on-line tests Study Buddy
100 50 0 % recall Time (days) 1515 Long Term Memory
To Make Learning stick Learn a topic Repeat in 24 hours Repeat for ten minutes at the end of a week Repeat again for 10 minutes a week later etc
English and Maths Key
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text: A founding person in the 116 Clique, Christian rapper Sho Baraka was created in Alberta, Canada but grew up in Southern California through the rise of gangsta rap. Sho cherished the music, but viewing a lot of his close friends go to prison after becoming a member of the gangsta life-style affected the aspiring rapper to select a different route. He remaining for university and Tx, but rap drawn him back, this time having a Christian spin as he created the 116 Clique in 2005 with close friends Trip Lee, Lecrae, and Tedashii. He released his solo profession two years later on with the recording Turn MY ENTIRE LIFE Up, then this year 2010 he released Lions & Liars, which would climb to number 3 on Billboard's gospel graph. Released in 2013, Skilled 10th topped that graph and presented a visitor appearance from his fellow 116 Clique member Tedashii. Baraka came back three years later on with his 4th LP, The Narrative (Humble Beast), which broke in to the Top Ten from the Billboard rap graph.


text: Great AHR 2017 for Build Products! We won two big awards & added a new team member... Welcome Kevin Scofield to the Build Products Team! Always nice to spend time with Ruth Ann - our favorite person in the industry!!!!! Mike McNultyFebruary 1, 20171 Comment Facebook0 Twitter LinkedIn0 0 Likes


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Footwear That Supports the Healthy Development of Little Feet
When my girls were babies, my aunt would hand-crochet baby booties for their tiny feet. There really wasn't a great selection of infant shoes available like there are today.
I recently was sent a pair of adorable toddler brown Leather Soft Sole Booties from Robeez. With a one-year old grandson on the run, these slippers will keep him toasty all winter!
Robeez is one of the most well-known manufacturers of premium, leather footwear for newborns, infants, toddlers and pre-schoolers. In September 2006, Robeez was acquired by Stride Rite Corporation, which is home to a portfolio of great footwear brands. Robeez is the 'only brand' of baby footwear that creates moments to delight in, so they're a perfect gift for celebrating the Holiday season.
Robeez baby shoes and baby booties are made out of the softest leather with soles that are flexible and durable. We also know baby needs to look cute, so Robeez baby shoes come in over 700 adorable designs!
These adorable booties will warm up any wardrobe. Beige flecked with cream and cuddly soft, there's a teddy bear plush lining which will provide warmth and protection for tiny toes.
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- Approved by the American Podiatric Medical Association
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Enjoy Free Shipping on purchases until December 9, 2009!
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© Moomettes Magnificents
Benefited Reviewer. Opinions are my own.
Moomette's Magnificents is hosting a Giveaway Contest! For a chance to win, there will be one (1) winner of one pair of Robeez from the Holiday collection. Robeez can only confirm gender and size, not the style of shoe (but you can still request a particular product if you wish when you win.)
Please include a way of contacting you. Should you be the contest winner, this information may be shared with the contest sponsor in order to send your prize.
Main Rule: (remember if this rule is not followed then no others will count)
a) Sign up for my free Newsletter Updates to my blog through my e-mail Feedblitz link (on the top of my right column or let me know if you already are, in a separate comment) AND
b) Visit Robeez and leave a comment about what you like best about their site and another product you'd like to try.
This contest will run until December 10 at 11:00 pm. EST
For Additional Entries, check out my Contest Entry Rules.


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2019 Reading Series
Yellow Arrow Publishing presents:
Buffalo in the Book
An Interactive Reading Series
Our quarterly reading series seeks to push the limits of current literary norms. Through the exploration of various themes, our featured writers will engage in panel discussions after presenting their work. Attendees are invited to participate in the exploration of the theme through various interactive art forms.
August 2: Literary Night
August 2, 2019, 5 - 9 PM
This reading series event will be held in conjunction with the Highlandtown First Friday Art Walk. Come meet a variety of artists at various venues in Highlandtown. Hear readings by writers and poets, and meet or purchase books from a number of our local women authors.
More information here.
November 3: Music and Literature
November 3, 6 - 7 PM
Atomic Books
Panel discussion and workshop featuring Kristina Gaddy.


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Divine eatery is a restaurant established in 2003 to meet the demand of people who are in need of specialized food and catering services in Nigeria.
Our food is affordable and we have excellent customer service in a conducive and relax environment.
You are welcome to a quick service restaurant in Nigeria where you are always treated with good service.
Divine eatery is managed by a team of trained professionals with specific competence in the food industry.
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Repetitive sequences of carbonate deposits, occurrence include in the lower part of the Paleogene Carbonate Unit (northeast border of the Madrid Basin), have been studied, defining regressive lacustrine sequences and early diagenetic processes. Binocular microscopic examination, scanning electron microscopic/energy dispersive X-ray observations, and X-ray diffraction analyses joint to isotopic studies ( δ 18 O and δ 13 C) have been used to characterise the facies and environments. The sequences consist of a lower uncemented carbonate mud unit, calcitic or dolomitic in composition, and an upper carbonate unit (arenites, bioclastic limestones, and microbial laminated limestones with cherts). Visual features (vertical prismatic structures, fissures, massive nodulization, rhizoliths, brecciation) and microscopic features (micrite micronodules, vug porosity, circumgranular cementation, gypsum lenticular crystals) outline pedogenic processes. These features, found locally in bioclastic and microbial laminated limestones or in dolomite uncemented muds, define, respectively, palustrine limestones or dolocretes. Facies analysis allows us to define several lacustrine sub-environments (basinal, littoral, eulittoral and supralittoral) and characterises different types of shallowing upward lacustrine sequences, either with or without subaerial exposure. The isotopic values of the bioclastic and microbial laminated limestone (from −5.77‰ to −6.78‰ for δ 13 C, and from −5.25‰ to −5.53‰ for δ 18 O) and those of uncemented calcitic muds (from −5.80‰ to −7.01‰ for δ 13 C, and from −4.98‰ to −5.58‰ for δ 18 O) establish that both types of carbonates precipitated in equilibrium with meteoric waters. In the palustrine carbonate deposits, the δ 13 C values suggest a strong organic contribution. The dolomitization that only affected the uncemented carbonate muds is early interpreted because of the structural and compositional characteristics of the dolomite (micro-rhombic dolomicrite, nearly stoichiometric and poorly ordered), and because the calculated average Δ 18 O dol–cal for calcitic and dolomitic uncemented muds is about 6‰. The δ 18 O isotopic values indicate that the dolomite precipitated from water that was slightly more enriched in heavy isotopes than the calcite, because of an increase in evaporation rates. Nodules and nodular levels of cherts occur in the upper units of littoral and eulittoral sequences, probably as a consequence of the existence of microbial mats that could include the silica source. According to their mineralogy (Opal CT and quartz/moganite) and structures (double nodules, lamination and bioturbation), three types of chert are described (TB, MB and WO). These types define three general stages of silicification during the early diagenesis, from the recently buried to the postcompactation of carbonate deposits. The δ 18 O values of quartz show that the silicification and ageing of opaline phases occurred from meteoric waters, which were lighter than the calcite or dolomite precipitating waters. The cherts included in palustrine limestones show δ 18 O values of quartz that record more evaporated waters than those of the general stages of silicification.
Sedimentary Geology – Elsevier
Published: Jul 15, 2002
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Best Places To Meet Transgenders In Montreal
When looking for places to meet transgenders in Montreal you have some options, but don't expect things to be easy. This is not somewhere like Bangkok where they are around every corner, but you can still find some around if you know where to look.
Of course the LGBT nightlife in the Gay Village will be what a lot of this post is about. Many still do prefer to go out and pick up people at bars, but tracking down sexy TS in a bar is no guarantee by any means.
If that sounds like your style then our LGBT nightlife section will really help you meet transgenders in Montreal. But that is not the only way, we also will tell you about a popular LGBT event and how you can meet transgenders near you online on t4m dating sites at any time.
TS girls are still in the minority so it will take some effort to meet them, but don't worry we have some solid tips for you. Hopefully as time goes on and more continue to transition this will all become easier and easier.
We have covered trans in Toronto and Edmonton if either also interest you.
LGBT Nightlife In The Gay Village
The Gay Village has been the main gay bar district in this city for many years. Now it is known as the LGBT bar district because we must always be politically correct, right?
However going out looking for transgenders in Montreal's Gay Village may not be as easy as one might think. Yes, there are more shemales here than their used to be, but that doesn't mean you can just snap your fingers and find a sexy TS girl to hook u pwith.
One night you might go to every bar on this list and not find a single one. Another night you might see six hot trans in the first place you walk inside. This is going to take effort, patience, and a whole lot of luck.
Some good LGBT bars to look for transgenders in Montreal are:
We included a map, the main drag of LGBT bars is located on Rue Sainte-Catherine. Speaking of drag Mado Lamotte has been putting on live drag shows in Montreal for years and is still going strong today.
Another good bar to see drag shows is Le Cocktail. Hopefully you get lucky and some of the performers stick around after the show, or other transgenders are in the crowd to watch as well.
Club Unity is the biggest LGBT nightclub in the city and is always a good place to go hunting.
Festival TransAmeriques
The Montreal Festival TransAmeriques is held in late May/early June each year and is one of the bigger LGBT events in Canada. Try to make it out to this great event if you can, there should be a strong contingent from the transgender community here.
You will be able to meet new ts girls from all over the country like from Quebec City or Vancouver, and hopefully find many who live right here in this city as well.
Meeting Montreal Trans Online
This final section is all about meeting transgenders in Montreal online on a great TS dating site. The truth is that many are not going to feel comfortable trolling LGBT bars in the Gay Village and walking up to a trans in a crowded bar.
Some people may be ready for that, but a lot of us value our discretion and know that people will gossip. That is where MyLadyboyDate can really help you out, it is the biggest transgender dating network in Canada and also the biggest in the world!
TS girls are usually very active online, many of them value their discretion as well. While some have the courage to let the whole world know who they really are some don't want to spend a lot of time getting all dolled up to go to the Gay Village and get stared at.
There are numerous reasons why it is easier to meet transgenders online that in person and we don't want to get into all of them. It should also be pointed out that t4m dating sites are always a more efficient use of your time no matter who you are trying to meet.
The bottom line is if you want serious dating, to find a trans life partner, or just to hook up with a sexy TS girl MyLadyboyDate is going to be the easiest and quickest way to make it happen. There are many places to find transgenders in Montreal, but that doesn't mean you don't have your work cut out for you.


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The Home Builders & Remodelers Association of Mohawk Valley has announced that the 2017 Home Show will be held April 1 and 2 at the Jorgensen Athletic Center on the MVCC-Utica Campus.
Open to the public, the show has been a local highlight each spring since 1994, and is one of the largest shows in central New York, typically showcasing more than 140 homebuilders and remodelers. Last year, more than 3,000 people attended the Home Show. The 2017 show is sponsored by the Utica Observer-Dispatch, CBS Utica, First Source Credit Union, and New York Sash
This year's event will feature displays exhibiting new products and services for local homeowners. Exhibits include the latest in new technologies from homebuilders and developers, remodeling and home improvement contractors, and building materials suppliers. Additionally, companies such as HVAC, landscaping, pools and spas, appliances and lending institutions will also be represented at the Home Show.
The MVCC carpentry class, under the guidance of instructor Ricardo Rosero, will also be building a storage shed on-site during the show on Saturday. Show attendees will have a chance to enter a $5 raffle to win the shed. The shed winner will also have the opportunity to choose the participating non-profit group to receive raffle proceeds.
The Home Show will run from 10 a.m. to 6 p.m. Saturday, April 1, and 11 a.m. to 4 p.m. Sunday. Visit hbrmv.com/home-show/ for more information.


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Horrific accident on R72 at Kleinemonde
Kleinemonde resident Colin Ashwell took these photos of the aftermath of the accident that took place between a truck and a car on the R72 this morning.
The number of people injured or fatalities are not yet known.
"It would be nice if our traffic officials would take note and try to make it safer from overtaking idiots," Ashwell said.
Last week Talk of the Town posted a number of photos of illegal overtaking across the solid white line on the R72, between the stretch of road from Fish River to Port Alfred.


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One of your last chances to own Castle Rock Lake Shoreline! This buildable 1.09 acre lot offers our 231' of owned shoreline on Wisconsins 4th largest lake. Includes an older septic system and a garage. (Septic may not be up to code). Breathtaking views from every direction, park your boat/watercraft directly in front of your lake home!
Features Lots and Acreage
|Total Acres: 1.09
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|Elementary School: Grayside
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|High School: Mauston
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|Body of Water: Castle Rock Lake


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The introduction of technologies such as mass spectrometry and protein and DNA arrays, combined with our understanding of the human genome, has led to renewed interest in the discovery of novel cancer biomarkers. Furthermore, the morden technologies provide the means by which new, single cancer biomarkers could be discovered through use of reasonable hypotheses and novel analytical strategies. Despite the current optimism, a number of important limitations to the discovery of novel single cancer biomarkers have been identified, including study design bias, and artefacts related to the collection and storage of samples. Despite the fact that new technologies and strategies often fail to identify wellestablished cancer biomarkers and show a bias toward the identification of high-abundance molecules, these technological advances have the capacity to revolutionize cancer biomarker discovery.
Gene-expression profiling
Genomic microarrays represent a highly powerful technology for gene-expression studies. Over the past decade, a tremendous growth in the application of gene-expression profiling has been witnessed. This growth has contributed to the cancer subclassification theory, insights into cancer pathogenesis, and the discovery of a large number of diagnostic cancer biomarkers. Despite promising proof-of-principle data, the successful use of gene arrays to discover novel subtypes of various carcinomas, and the utilization of these technologies for discovery of diagnostic cancer biomarkers, these new tools are not yet recommended for widespread clinical use by either organizations issuing clinical guidelines or expert panels
Mass-spectrometry-based proteomic profiling
Proteomic-pattern profiling is a recent approach to cancer biomarker discovery. Given that mRNA information does not best reflect the function of proteins, which are the functional components within organisms, the use of proteomic patterns to enable tumor diagnosis or subclassification seems more promising. Mass-spectrometry- based methods of proteomic analysis have improved and include more-advanced technology that brings higher mass accuracy, higher detection capability, and shorter cycling times, thereby enabling increased throughput and more-reliable data.
In spite of the optimism regarding this approach, a number of important limitations have been identified. These shortcomings include bias from artefacts related to the clinical sample collection and storage, the inherent qualitative nature of mass spectrometers, failure to identify well-established cancer biomarkers, bias when identifying high-abundance molecules within the serum, and disagreement between peaks generated by different research laboratories. Another limitation concerns possible bioinformatic artefacts. Despite a substantial time lapse since the first report of this technology, no product has yet reached the clinic and no independent validation studies have been published. Guideline-developing organizations and expert panels do not currently recommend serum proteomic profiling for clinical use.
The low-molecular-weight plasma or serum proteome has been the focus of recent attempts to find novel cancer biomarkers. Peptidomic profiling might represent nothing more than peptides cleaved during coagulation or functions inherent to plasma or serum, including immune modulation, inflammatory response and protease inhibition. Many of the aforementioned caveats associated with mass-spectrometry- based protein profiling technologies also apply to peptidomics.
Cancer-biomarker-family approach
The premise for the 'cancer biomarker family' approach is that if a member of a protein family is already an established biomarker, then other members of that family might also be good cancer biomarkers. For example, PSA is a member of the human tissue kallikrein family. Kallikreins are secreted enzymes with trypsin-like or chymotrypsin-like serine protease activity. This enzyme family consists of 15 genes clustered in tandem on chromosome 19q13.4. PSA (KLK3) and KLK2 currently have important clinical applications as prostate cancer biomarkers. Other members of the human kallikrein family have been implicated in the process of carcinogenesis and are being investigated as biomarkers for diagnosis and prognosis. For example, KLK6 has been studied as a novel biomarker for ovarian cancer.
Secreted protein approach
In theory, a candidate serological tumor marker should be a secreted protein, because secreted proteins have the highest likelihood of entering the circulation. Examination of tissues or biological fluids near to the tumor site of origin could facilitate identification of candidate molecules for further investigation. The increasing evidence that tumor growth and progression is dependent on the malignant potential of the tumor cells as well as on the microenvironment surrounding the tumor (e.g. stroma, endothelial cells and immune and inflammatory cells) further supports this approach.
It should be noted that some of the widely used cancer biomarkers such as CEA, CA125 and HER2 are actually membrane-bound proteins, which are shed into the circulation. The identification of secreted proteins in tissues or other biological fluids does not necessarily imply that the proteins will be detectable in the sera of cancer patients. Serum-based diagnostic tests depend on the stability of the protein, its clearance, its association with other serum proteins and the extent of post-translational modifications.
Other prominent strategies
A number of other strategies for detecting cancer biomarkers exist. One approach that is gaining popularity is based on protein arrays. Another prevailing view is that tumor-associated antigens could serve as biosensors for cancer because tumors naturally elicit an immune response in the host. Moreover, breaking the cancer genetics dogma that hematologic malignancies result from chromosomal translocations and that mutations underlie epithelial solid tumors, gene fusions as a result of translocations in prostate cancer have been identified through use of gene-expression data sets. In addition, mass-spectrometrybased imaging of fresh-frozen tissue sections has yielded a number of potential candidate molecules. Besides proteomic profiling of serum, attempts have been made to decipher the serum proteome via numerous fractionation schemes to simplify and reduce the dynamic range of molecules present in serum. Finally, the use of animal models involving human tumor xenograft experiments has also shown promise for biomarker discovery.
The first cancer biomarker ever reported was the light chain of immunoglobulin in the urine, as identified in 75% of patients with myeloma in an 1848 study. The test for this marker is still employed by clinicians today, but with use of modern quantification techniques.
From 1930 to 1960, scientists identified numerous hormones, enzymes and other proteins, the concentration of which was altered in biological fluids from patients with cancer. The modern era of monitoring malignant disease, however, began in the 1960s with the discovery of alfa-fetoprotein and carcinoembryonic antigen (CEA), which was facilitated by the introduction of immunological techniques such as the radioimmunoassay.
In the 1980s, the era of hybridoma technology enabled development of the ovarian epithelial cancer marker carbohydrate antigen (CA) 125. In 1980, prostate-specific antigen (PSA [KLK3]), considered one of the best cancer markers, was discovered.
Every era of biomarker discovery seems to be associated closely with the emergence of a new and powerful analytical technology. The past decade has witnessed an impressive growth in the field of large-scale and high-throughput biology, which has contributed to an era of new technology development. The completion of a number of genome-sequencing projects, the discovery of oncogenes and tumor-suppressor genes, and recent advances in genomic and proteomic technologies, together with powerful bioinformatics tools, will have a direct and major impact on the way the search for cancer biomarkers is conducted. Early discoveries of cancer biomarkers were based mainly on empirical observations, such as the overexpression of CEA. The modern technologies are capable of performing parallel rather than serial analyses, and they can help to identify distinguishing patterns and multiple markers rather than just a single marker; such strategies represent a central component and a paradigm shift in the search for novel biomarkers.
Cancer biomarker discovery and development falls into five conceptual phases: preclinical exploratory studies; clinical assay and validation; retrospective longitudinal studies; prospective screening; and randomized control trials
Preclinical exploratory studies
In this phase, tumor and non-tumor specimens are compared to generate hypotheses for clinical tests for detecting cancer. Strategies such as geneexpression profiling, mass-spectrometry-based methods and other approaches to cancer biomarker discovery can be used to aid this phase.
Assay development and validation
A clinical assay that uses a specimen of choice (usually something that can be obtained noninvasively) is developed in this phase. The assay must discriminate individuals with cancer from those without. The patients assessed in this phase have established disease. The utility of the assay in detecting disease early is not demonstrated in this phase.
Retrospective longitudinal clinical repository studies
Specimens collected and stored from a cohort of healthy individuals who were monitored for development of cancer are used here. Evidence for the capacity of the biomarker to detect preclinical disease is demonstrated in phase 3. Criteria for 'positive' screening results are defined and used in phase 4.
Prospective screening studies
In this phase, individuals are screened with the assay and diagnostic procedures are applied to those who screened positive. This can help to establish the tumor stage or the nature of the disease at the time of detection.
Randomized control trials
The objective of this phase is to determine if screening reduces the burden of cancer in the population.
Canonical Wnt Pathway
Complement Activation Pathways
Death Receptor Signaling
EGFR Signaling Pathway
NF-kB (NFkB) Pathway
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Notch Signaling Pathway
p53 Pathway
TGF-beta Signaling Pathway
TNF Signaling
VEGF Signaling
Cytokines & Growth Factors
Cell Lysates
cDNA & qPCR Primer
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Stem Cells
Developmental Biology
Cell Biology
Signaling Pathways
Influenza Research Reagents
Adhesion Molecule
Cancer Biomarker
CD Molecule
Growth Factor
Fc Receptor
Disease Therapeutic Target


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A new top of the range helmet designed for travel maxi enduro owners.»
Strong, practical and technical, it is the ideal companion for all bikers, especially off-roaders.»
Discover the GIVI accessories that best suit your taste and your needs!
Do you want to get the best out of your bike with GIVI products?
Find the dealer nearest you!
Would you like to fit out your motorbike with Givi's accessories? Thanks to this brand new virtual tool, Givi will help you find accessories which will be perfect for you and your requirements!
Specific footguards in ABS
Specific footguards in ABSLook for the section MY MOTORCYCLE to verify the compatibility of the specific article for your motorcycle


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Rawalpindi starts a rule for the motorcycle driver who did not wear the helmet will not purchase petrol for motorbike. Now the district administration of Rawalpindi started a rule "No Helmet No Petrol " on all petrol pumps in the city. The main purpose for starting this rule is to promote the government campaign about helmet wearing is compulsory for the motorcyclists.
Lahore High Court has passed strict order to the petrol pump to ban selling petrol on the motorcyclist not wearing a helmet. The main purpose that the government forced the authorities to take strict action for helmet wearing is just to better the system and trying to control road accidents.
Moreover, the government starts a different campaign to set up the proper traffic rules and force citizens to follow the traffic rules if they don't want to pay fine.to impose the fine on rule violating is just to promote this culture in people to don't violate the law and keep maintain the discipline in the country


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One of the finest estates ever offered on the Eastern Shore, Tred Avon Manor offers the very best of classic Eastern Shore Living. The park like grounds consist of 16 + acres on a southerly facing peninsula lot with deep water, and up to 1,200 +/- ft of protected shoreline on the Tred Avon River. Improvements to the main parcel include a 9000 +/- square foot manor house that is a stunning example of modern construction while utilizing the very best of classic architecture. Features include living spaces suitable for both formal and casual living. There is a well-equipped chef~s kitchen with commercial appliances, and a full butler~s pantry. The gorgeous master suite has double walk in closets, fireplace, and a private office. The dining room is generously sized, and opens into the sunroom for entertaining. Other improvements include a proper, full size, 3 bedroom guest residence, large pool with pool house, pier with deep water slips, and even a heated in ground duck blind for waterfowl hunting. Additional, contiguous waterfront home available to the buyer of the main residence that includes a well maintained home, pier and waterside pool.
Attic, Built-Ins, Butlers Pantry, Carpet, CeilngFan(s), Chair Railing, Crown Molding, Double/Dual Staircase, Formal/Separate Dining Room, Master Bath(s), Pantry, Recessed Lighting, Upgraded Countertops, Walk-in Closet(s), Wet Bar/Bar, Wine Storage, Wood Floors, Bar, Wpool Jets, Cedar Closet(s)
Garage - Front Entry, Garage Door Opener, Oversized
Trees/Woods, Panoramic, Scenic Vista, River
Dishwasher, Disposal, Dryer, Exhaust Fan, Icemaker, Instant Hot Water, Microwave, Oven-Double, Oven-Wall, Oven/Range-Gas, Range hood, Refrigerator, Stainless Steel Appliances, Washer, Water Heater, Commercial Range
Exterior Lighting, Outbuilding Apartment, Private Beach, Pool (In-Ground)
Landscaping, Partly Wooded, Private, Rip-Rapped, Secluded, Trees/Wooded
The listing content relating to real estate for sale on this web site is courtesy of MRIS. Listing information comes from various brokers who participate in the MRIS IDX.Properties listed with brokerage firms other than Coldwell Banker Chesapeake are marked with the MRIS Logo and detailed information about them includes the name of the listing brokers.The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed and should be independently verified.All listing information copyright MRIS 2019.
Listing information last updated on October 17th, 2019 at 12:03am EDT.


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'Caramel Slice'
For the base:
100g Pitted dates
100g Almonds
50g Walnuts
80g Oats (gluten free if required)
For the caramel:
160g Pitted medjool dates
45g Almond butter
50ml Warm water
2tsp Pure maple syrup
For the chocolate layer:
100g Dark chocolate (at least 70%)
1 tsp Coconut oil
1 tsp Pure maple syrup
Start by placing the pitted dates in a bowl and cover with boiling water. Leave to stand for at least 10 minutes.
Meanwhile, start on the 'caramel'. Place the medjool dates in a blender and blast until a paste is formed.
Add the warm water and blend again before adding the almond butter and maple syrup.
Leave to process for a couple of minutes or until it forms a caramel texture. Cover and place in the fridge.
Now we can go back to the base, place the dry ingredients in the blender and process until it forms a breadcrumb texture.
Drain the pitted dates and add to the blender. Process until everything is well combined and sticking together.
Line a baking tin with foil, then press the base mixture firmly into the tin.
Grab the caramel from the fridge and evenly layer this over the base then cover and return to the fridge for at least 20 mins.
Now for the final layer! Bring a pan of water to a gentle simmer then place a heatproof bowl over the pan.
Add the chocolate, coconut oil and maple and stir until everything has melted and combined.
Remove the tin from the fridge and layer the melted chocolate over the caramel.
Return to the fridge and leave to cool for a couple of hours or until the chocolate has set.
Slice into 12 squares and keep in the fridge to prevent the chocolate from melting.


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I love destination weddings! Everything is new and exciting! There is a fun energy that comes with destination weddings. I was able to take some time to explore this micro town in Mexico. I had an amazing time with both brides and their entire wedding party! Thanks to Willa and Brittany for including me in your special adventure/wedding!!!
Santa Barbara Wedding Expo!!!
I'm super excited to be a part of Central Coast Bride's Wedding Expo in Santa Barbara this Sunday, Jan 20, 2019! Come down and visit me! I will be giving away prizes and I would LOVE to meet you!


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Wednesday Nights Bible Study
We meet at the church in the Mary Cook Room at 7:00pm.
We suggest parking in the parking lot on Jarvis street between Lane and Fremont street. Call the church office at 956-723-5714 for more information
We will be looking at the Way of Love Bible Lessons to be used on the Sunday after each of these Wednesdays. Open to all.
(For those who want to stay after the study, at 8:00 we will have an Holy Communion Service from 8:00 p.m. to 8:15 p.m.)
Call the church office at 956-723-5714 for more information about bible study and more.
Tuesday Morning Adult Bible study
meets on Tuesday Mornings from 10:30 - 11:30 a.m. in local homes. Call the church office for details. (956 -723-5714) We will be working on the Way of Love Bible lessons. Open to all.


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Caring for Your Collection
Although works of art on paper such as prints, drawings, and watercolors are inherently fragile, they can be easily and effectively protected from damage and deterioration using these guidelines.
Works of art on paper should be touched as little as possible. Hands should be clean and dry before handling paper items, as the oils from fingers can cause staining on the paper. If possible, mat, frame, or store the works in a manner that permits viewing and transporting without direct handling.
Paper materials are damaged by prolonged contact with acidic surroundings. Mats, folders, and mounting adhesives must be chemically stable, non-staining, and permanent by reversible. It is important to use archival-quality materials. A common sign of poor mat board is browning of the cut edge of the window opening. If you are unsure of how to identify the material in your framed artwork, consult a paper conservator.
Archival framing standards:
Use a mat window and backboard made of 100% ragboard or lignin-free, alkaline-buffered matboard.
Attach artwork to the mat or mount by hinging it with high-quality archival tissue and a permanent, nonstaining, reversible adhesive. Homemade starch paste is the choice of conservators. Avoid commercial tapes, including those advertised as archival.
Use protective glazing, either glass or Plexiglas. The artwork must not be in direct contact with the glazing material. Ultraviolet filtering products are recommended to protect against UV light. Note that acrylic carries a static charge and must not be used with pastels, charcoal, or other powdery or flaking medium.
An additional protective layer or sturdy, lignin-free board should be used in the back of the frame. The frame should be well-sealed to discourage any entry of air or insects.
To prolong the life of your unframed paper items, they should be stored individually in acid-free alkaline folders, Mylar, or alkaline mats. Alkaline storage material provides a desirable neutralizing affect on acidity.
Please see here for our list of suggested vendors for archival storage materials.
Storage recommendations:
It is best to store paper items flat, rather than folding and unfolding, which can lead to creases and tears.
To protect the edges of items, folders should be larger than their contents.
Mylar has the benefit of being clear and can also provide support, but is not alkaline. Mylar can have an electrostatic charge, which damages friable media such as unfixed pastel and charcoal, heavily applied pencil, and flaking media.
Oversized items are best kept in flat file drawers. These files should be made of metal rather than wood because of the acidic gasses emitted by wood.
When storing highly acidic materials, such as newspaper clippings or telegrams, the items should be isolated to avoid acid migration.
Light causes fading of certain media, especially watercolor, pastels, and many drawing inks. It can cause paper to bleach, become yellow, darken, and can severely embrittle the cellulose fibers of the sheet. Light damage is cumulative and irreversible.
Optimal display conditions are those with low light levels and no daylight exposure. Light sources containing ultraviolet (UV) rays are especially harmful. UV is found in all sunlight and in the emissions of certain artificial lights, such as some fluorescent and metal halogen lamps.
Special filters are available to screen out UV rays. Inexpensive plastic sleeves which filter UV rays can be placed on fluorescent tubes. Windows or frames can be covered with stick-on UV-absorbing films or rigid sheets of UV-filtering plastic. Because all light is damaging to art, conservators recommend that no work on paper be permanently displayed. In some cases, a high-quality photocopy or reproduction can be a good substitute for a light-sensitive original.
Pollution, Dust, and Pests
Dust and soot will soil delicate, porous paper surfaces and are difficult to remove safely. Pollutants, such as ozone and fumes from photocopy machines, car exhausts, and heating systems can cause damage to paper. Alkaline storage materials may help provide a buffer to these pollutants. Paper materials should be protected from dust and dirt using the storage systems mentioned above.
Monitor for evidence of rodents and insects. Silverfish, book lice, and book worms can eat, soil, and damage paper; good housekeeping and preventative environmental conditions will help reduce the threat of these pests.
Temperature and Humidity
Store paper materials in a cool, dark, dry location. Ideal conditions are 35% relative humidity and below 72° F. Avoid light, heat, and dampness. Maintaining steady temperature and relative humidity is preferable over cyclical conditions. Climate fluctuations cause expansion and contraction, which can lead to structural damage in paper, weaken the attachment of media, and cause distortions such as rippling.
High humidity can lead to the development of foxing (small, brown, disfiguring spots in paper) or mold growth. Frames and storage enclosures may provide some degree of protection against daily fluctuations but will not protect paper from long-term or seasonal changes. Due to climate fluctuations, do not store works in basements or attics. Do not hand them in bathrooms or over heat sources.
For more information, see guidelines from the Library of Congress: www.loc.gov/preserv/care/paper.html


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Excel provides a few helpful features you can use to change the way worksheets display. You can set up your workspace for specific tasks and then save the same view settings for the next time you need to perform the same task.
Worksheet panes let you view different areas of your worksheet simultaneously. You can split any worksheet in a workbook vertically, horizontally, or both vertically and horizontally, with synchronized scrolling capabilities. On the worksheet shown in Figure 12-17, columns B through M and rows 4 through 37 contain data. Column N and row 38 contain the totals. In Normal view, it's impossible to see the totals and the headings at the same time.
Figure 12-17. You can scroll to ...
No credit card required


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THE first of the North East's little cuties lined up yesterday for our Baby Idol 2009 contest.
Hundreds of proud parents visited Eldon Square for their free photo shoot in a bid to prove their baby is the bonniest in Toon.
Little Josie Matilda Gill, five months, lit up the room with her infectious smile.
Proud mum Nicola Laing, 37, from Fenham, Newcastle, said: "Josie is always like that, content and smiling. Everyone is always saying how pretty she is with her jet-black hair.
"I saw the queues as we were shopping and just decided to enter her. Now I'm hoping she will win. I've already been on the phone to everyone I know to tell them to vote for her."
There is still plenty of time to put your little one in the frame alongside Josie.
It is absolutely free to enter and we've teamed up with Eldon Square to offer some top prizes. Winners will receive a £500 Eldon Square Gift Card, a 20in x 16in laminated framed portrait and their winning trophy. Runners-up will also receive gift cards, a portrait and trophy. You can enter by cutting out the Baby Idol photo session voucher. Simply take it along to the photographer's stand in Eldon Square on Blackett Bridge, outside of Top Shop, to have your free Baby Idol photo session. Our photographer will be there every day from 10am until 4.30pm until Wednesday, November 4.
You will then be asked to return to Eldon Square between Thursday, November 5, and Sunday, November 8, to select which photo you would like to appear in the Chronicle's Baby Idol supplement.
The competition is open to youngsters up to the age of three. There are three categories: 0-nine months, 10 to 18 months and 19 to 36 months.
Once entries are published, it's down to readers to vote for their favourite by phone or text.
Standard Trinity Mirror plc rules apply, available at www.chroniclelive.co.uk/legal . Log on for full terms and conditions.


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All item details
Ultra-lightweight and super comfy: these trousers adapt to your figure and are perfect for sports and leisure activities.
- Very lightweight, easy-care fabric with stretch for comfort and E-DRY technology
- E-DRY: lightweight, quick-drying and breathable
- Wide, comfortable elasticated waistband with drawstring ties
- Two side slit pockets
- Loose leg width
- Fixed hem edges
Size info
- With size S (can vary slightly depending on the size):
- Inseam length: Approx. 74 cm
- Leg opening: Approx. 30 cm
Material and care
- Outer fabric: 87% Polyester, 13% Elastane
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Customer ratings
Active elastic waist trousers, E-DRY
Overall rating:
(3 of 5 stars)
Didn't like the material as I wasn't planning to use it for working out.
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