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Turn Your Fears into Goals
How to start taking action today.
I break out in a nervous sweat at the thought of networking. It's mostly a fear of not knowing what to say when I meet someone new.
To get over this fear, I had to come up with a few practices I can take action on regularly. I want to share those practices with you because they can be applied to any goal or fear you are trying to conquer.
- Set Bite-Sized Goals
What is at the core of your fear and what small thing can you act on regularly to overcome it?
The core of my fear is starting a meaningful conversation with people I do not know.
To get over this I set a small goal for myself that I can accomplish every day: talk to a stranger. In an elevator, checking out at the grocery store, buying coffee. Any chance I get, I want to try to connect with someone to practice getting over that initial fear.
To identify your own small daily goal you can take action on, think about what makes you most anxious about your fear.
For example, if your goal is to do more public speaking, your anxiety might be being the center of attention. What are the smaller, everyday steps you can take to practice being the center of attention? It could be presenting internally to your team or to your family once a week.
Whatever it is, find something small you can accomplish every day or every week.
2. Be Aware of Opportunities for Facing Your Fear
After setting my daily goal, I started to become aware of opportunities throughout my day for talking to a stranger. When I identify that opportunity (e.g. being alone with someone on the elevator), my instinct is to pull out my phone and be quiet, but instead I recognize the chance to act on my goal and just go for it.
I'm actually starting to love these opportunities. It's becoming a little game to the point where now I seek out situations where I'll be surrounded by people I don't know so that I can practice starting and holding a conversation with them.
You will start to notice these opportunities too. Don't shy away from them, embrace them. Listen to that voice inside of you and take the leap and remember that Kelly McGonigal says stress is just your body's way of preparing you to face a challenge.
3. Measure Your Progress
There is nothing more rewarding than looking back in time and seeing concrete items that prove you are taking steps to achieve your goals.
I built a simple scorecard for myself to keep track of every time I achieved my daily goal of talking to someone I don't know. It looks like this:
Pretty simple, right? But it's a great feeling at the end of the week to look back and see that 4/5 days I hit my goal.
This step is crucial because it will encourage you to keep going. On days when you feel like you're still being crushed by your fear, look at your scorecard and acknowledge all the times you actively faced that fear. It will motivate you to keep going.
Consistently acting on your small goals is what leads to conquering your big goal.
4. Tell Someone What You're Doing
Talking to someone about your fear may be a little awkward at first (especially for someone like me who doesn't like being vulnerable) but you have a better chance of achieving your goals if you are being held accountable by others. So tell someone what you're working on and what your goals are. It's all the better if they share that goal so you can help each other through it.
Tell this trusted friend or family member to ask you about it occasionally. It seems simple, but knowing they are checking up on you motivate you so you have some success to report.
Also, if people know what your goals are and what you're working on every day, they can help you. They may suggest ways to achieve your smaller goals, introduce you to people who can help, give you tips, or give you opportunities to act on your fears.
You can take a small first step and write your goal on a sticky and put it somewhere you'll see it all the time. This is a great way to hold yourself accountable and keep your goal top of mind.
5. Raise The Stakes
I love to run, but I am not the most disciplined person. I need a big race or event to look forward to to push myself. I sign up for races a couple months out that are just beyond my capability so that I really kick it into high gear and start training.
This "hack" may work for you. If you have a fear of public speaking, tell your boss you want do a presentation in a few weeks or sign up to speak at a local event or conference. Schedule time with your manager to do a small presentation. Whatever it is, get something concrete on your calendar so that you have no choice but to prepare.
For me, I have a fear of networking, but I want to get more comfortable with meeting new people. To motivate myself, I'm signing up for networking events once a month that force me to consistently hit my small daily goals so that I'm prepared for these events.
Conquering your fear is no small task. In fact, if you take any action at all after reading this, you are leagues beyond the majority of people out there.
Action is the first step. Start small, with bite-sized goals and start taking action today.


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Community Trekker
Jan 14, 2015
I'm rather new to JMP and could not find anyone with a similar issue in the discussions section so I thought I'd ask all of you experts!
I have a series of .XLSM files that have had a macro run on them; within a cell you'll see something along the lines of {=(MACRO FORMULA)}. All the files are formatted the same way but before I can write a jsl script to do some data manipulation, I need to import them.
When I ask JMP to open the .XLSM file, the data that was originally there in the Excel file turns into a value labelled #NAME?.
What's interesting is that if I go into the excel file, then in the JMP tab, when I run the Data Table Macro, JMP goes and copies the data table perfectly (albeit it's transferred at a snails pace).
Going into the excel file and doing a copy>paste value and then running a script from there would be easy, but there are going to be almost 100 .XLSM generated monthly so this would grow inefficient. Additionally, while going into the excel file and running the JMP Data Table macro looks like it's the perfect solution, it's also taking approximately 5 minutes to convert a single file....also inefficient.
In any case, I'm open to suggestions and appreciate any feedback you all may be able to provide me.

subset: commoncrawl


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Mydolls, a punk/post-punk band and one of the first inductees into the Houston Music Hall of Fame, formed in Houston in 1978 when TRISH HERRERA (guitar and vocals) and DIANNA RAY (bass and chanting) began to write songs together. They were soon joined by LINDA YOUNGER (guitar and vocals), Herrera's cousin GEORGE REYES (drums), and ultimately Ray's wife KATHY JOHNSON until her death in 2011. Predominantly self-taught, the Mydolls play their instruments unconventionally. Younger sometimes plays only the top three strings of the guitar while Herrera concentrates on the bottom three, or vice versa, in order to achieve a layered sound. Reyes's Latin and tribal-influenced drumming complements Ray's unconventional bass playing and chanting.
The band's name came from the over-the-counter medicine Mydol used to relieve menstrual symptoms, and one of the most memorably named double bills in Houston punk history occurred when the Mydolls opened for the punk/rockabilly band The Cramps. Mydolls performed with other touring acts, including Siouxsie and the Banshees and Minor Threat. They began performing in the Houston punk community early, before the punk genre began to be more rigidly defined in the mid- to late 1980s. Early in their careers, they performed with Houston bands AK-47, Hates, Degenerates, Culturcide, Party Owls, Bevatron, Anarchitex and Really Red, as well as with Texas punk bands including Big Boys, Dicks, Meat Joy, Beatless, Buffalo Gals, Marching Plague, Stickmen with Ray Guns and Butthole Surfers. Their music was influenced by Red Crayola, Wire, Velvet Underground and the Raincoats.
In the 1980s, the Mydolls released three recordings on Houston's CIA Records. Mydolls songs appear on compilations Cottage Cheese from the Lips of Death (Ward-9 Records, 1983), Sub Pop 7 (Sub Pop Records, 1983) and The Dog That Wouldn't Die (CIA, 1986). A retrospective named after their single A World of Her Own was released by Grand Theft Auto (2007). Their song "Imposter" appears on French filmmaker Claire Denis's 2008 film 35 Rhums (35 Shots of Rum), and the band performed in a bar scene in the 1984 Cannes Film Festival award-winning movie Paris, Texas. In 2015, the Mydolls eight-song CD It's Too Hot for Revolution was released on the Betsey label.
In addition to touring widely in Louisiana and Texas, the Mydolls toured the Midwest in 1983 and the East Coast in 1984 on their Go to Fish tour. While on tour, they attended the opening of Paris, Texas in New York City.
The Mydolls disbanded in 1986 and reformed in 2008. Since then, the band has continued performed locally and nationally, playing in festivals and events including Noise and Smoke (2008), Denton 35 (2015), Meow Con (2013), and Fabulosa Festival (2015). The band still performs for benefits and are active in Girls Rock Houston.


text: The Joint Strike Fighter Program (JSF) will produce the most sophisticated warfighter in the history of military aviation. JSF is unique as a major weapons system acquisition program in that the economics of system operation, support, and maintenance are being development concurrently with the technology. The JSF Autonomic Logistics (AL) Program aims to minimize operational and support costs by increasing system reliability, reducing maintenance requirements to essential levels. Using Prognostics and Health Management (PHM), materials are ordered and maintenance is performed only when needed, obviating costly routine scheduled maintenance, and reducing aircraft downtime. This vision of efficiency and responsiveness implies real-time communication between the intelligent air vehicle, industrial contractors and their suppliers, and the aircraft maintenance and support team. All of these entities require access to diagnostics and prognostics based on usage data, operational and life cycle models, and historical information on maintenance to optimize decision making in support of PHM. Here, IAC addresses the need for an intelligent software infrastructure system to manage this complex system. This system features a ontology-enabled, service oriented software architecture for automated reasoners which analyze sensor data, PHM model outputs and past behavior to recommend actions under dynamic and uncertain conditions. BENEFITS: The potential application for this technology within the Federal government is significant. The immediate application will support the Joint Strike Fighter Autonomic Logistics (AL) Program. The software system IAC proposes to design and develop in this research addresses the need to provide near real-time communication between the intelligent air vehicle, industrial contractors and suppliers, ant the aircraft maintenance and support team. This system promises tremendous positive impact on the JSF Program bottom line. In addition, other large acquisitions systems within DoD and other agencies of the United States Government would benefit by using the technologies developed here. IAC is designing software components and services to maximize their potential for reuse with little extra software engineering effort. The system may have considerable potential commercial application in products where intelligent reasoning would enhance decision making on an automatic basis. Business office copiers might benefit by learning rules mapping fault conditions to required maintenance. Desktop computers could warn of impending disk failures. Household appliances and consumer electronics could be enabled with small-footprint versions of the present system to facilitate prognostics and diagnostics. IAC will explore some of these exciting commercial applications in the future.


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Expert in Astrology
Astrology is an ancient Indian science which based on planetary motions and positions of sun and stars in the horoscope of individuals. Earlier astrology was only based on the movement of planets with respect to stars, but later on it involved zodiac signs to predict the future and essential circumstances.
Hindu astrology or vedic astrology is about 7000 years old system of prediction & anticipation. Indian astrology uses date, place and time of birth to prepare of individuals horoscope.
Astrology helps in giving prediction about important phases of man's life like, career, marriage, business by judging stars movement and sun position in horoscope. Indian tends to rely on horoscope about marriage, love relationship and other important issues just because of our true and whole faith about astrology.
India is the vast believer of astrology than other countries. Indians are very sensitive about astrology and they believe and perform all ritual about their horoscope.
It consists of several system of divination based on the premise that there is a relationship between astronomical phenomena and events in the human world.
Astrology is the science of stars, and is based on the belief that the position of the planets and stars in the sky influences human life. Like in any other profession, the accuracy of the task depends on the person performing it. The failure of predictions could be because they are wrongly interpreted by astrologers, or incomplete and wrong birth information given. After all, predictions are based on mathematical calculations of transiting plants.
Palmistry: The lines on our palm are the imprint of our destiny as charted by our past and present karma. If one wants happiness and prosperity, one must do a good to other. By deceiving others, we only hurt ourselves. I can say with great conviction that these lines consistently reveal the truth. Astrology or palmistry is based on the law of karma.
There is an amazing synchronization in this universe. Everything is perfectly timed, but due to our karmic amnesia, our conscious minds are not aware of it. Astrology is based on the principle of karma. Probably that is why the path of good karma is more difficult to follow!
The planetary positions at the time of birth lay our destiny path, where and when we are likely to meet challenges, joys and happiness. Out birth time is actually the starting time of our journey on this earth, and is therefore important. Planetary positions at the time of birth will reflect its course, progress, success or failure.
All astrological streams are self-sufficient and complete. Being older than history, astrology has suffered repeated attacks. Some ancient scriptures have been destroyed or take away by invaders, but it is for the new generation of astrologers to try and fill these gaps.
We are amongst the best astrologer in India and known for our expertise and accuracy in astrological phenomenon. We are expert in Vedic astrology, kundli matching, horoscope reading, palm reading, and numerology. We have many entourage and beneficiaries who are the witness of our acute astrological perceptions. For more information and queries please contact us:
Guru Ji Ph.:+919876146495, +91-9878019497 Email: firstname.lastname@example.com
Website: www.vashikaranspecialist.com


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CabShare booking is very simple. You have to register once and then just search for the area for ride sharing. You can send out a fresh request too. Others are free to accept or decline the cabshare option. This saves you time and money.
CabShare is a free ride sharing application that has been launched for the convenience of the commuters like office goers, students' etc.in Delhi NCR.
It is very convenient to book and use, and is safe to board.
Booking is as simple as:
a) Register your e-mail address and your password
b) Once connected, browse through the various routes and options or a suitable cab or auto rickshaw journey and request to share it. The host may either accept it or decline your request.
c) If there is no journey already planned for the route, then a fresh request needs to be made and others can request to share it.
d) The drivers on receiving the request can instantly calculate the potential savings for each incoming request for the same or similar route travel. The passengers are free to choose to accept or decline the journey and the fare.
- Time is Money: It saves you the time of taxi booking online, waiting in long queues at the airports, bus or metros; non-availability of a cab or an auto in an area or of travelling at your preferred time etc.
- CabShare helps you use these door to door transport system at the most economical rates, at par with the public transport system, as the fare gets shared between the co-travellers.
Safe to board:
1) The ride is being shared with a profile chosen by you.
2) Usually, this ride will be shared by you with your known ones or the people you will be comfortable to share the same with
3) These are people from your local community, be it near home or around office.
4) This is a suitable option even for children's car pool.
5) Both the drivers and the vehicles (cab or auto) being used are legally registered and police vetted.
6) It's safe to board it on the way back from a social gathering as:
- You don't need to travel back alone on an isolated route at odd hours
- You don't need to be driven back by strangers or unknown taxis to or on your way back
- You can share a ride back and with someone known, whose details are on record on your phone and your e-mail.
- You don't mix drinking with driving!!!
7) Your family has the details of who you are with, and the expected time for your travel on that route. Thus, some mental peace, finally, for them!!!
8) Less likelihood of pick-pocketing or eve-teasing or any such petty crimes that we face in our day to day routines, which have become a part of the public transport commute.
9) CabShare cuts your waiting time at odd or isolated places for bus or any other form of public transport. Just Be Safe…call us and enjoy a ride to your destination in a safe vehicle at economical rates.
Thus, CabShare is becoming "The talk of the Town", as it the solution to many problems today!!!
CabShare is the service that helps provide a platform for social interaction, reduces pollution, helps curb the traffic problem (to some extent), reduces your wait time, and gets you a private transport facility at the public transport rates and ALL this comes without compromising your safety.


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|Scroll Stalker
Anything that you are dying to show off that you got for christmas?
|Scroll Desperado
Gift cards, clothes, cdr's and some other stuff. It's the stuff i gave i liked better. mama xc loved the cat music box i gave her (i gotta admit, it's a nifty looking & sounding thing) and the cat who owns me got a buncha toys (only plays with one of them so far and i have to fetch it when she loses it, what a stoopid trained human i am).
|Besotted Scroller
earrings from sis
air filtery thinger - mom/dad
cards, gift cards (best buy, b&n, itunes), t-shirt, earrings - friends
|Scroll Guardian
Season 1 box set of Sleeper Cell from Keri. Gift card from her parents for Borders, some ornaments for our 'first' christmas tree. Nice stuff, I went to Borders and cleaned up on books.
I <3 4 foot 11, blonde, operatic wonders from Oklahoma.
There is no charge for awesomeness or attractiveness
|Scroll Stalker
Rachel got me a stereo. It's been so very long since I've had a good sound system. She also got me an earpiece for my phone. She also got me these really cool "museum in a book" books. One on the Declaration of Independence and one on Ben Franklin. They are SO cool.
I got Rachel a ton of books from Borders....ATV Off Road Fury 4...Pirates 2 (awesome movie!)
It was a nice christmas....simple and uneventful....I loved it.
|Scroll Guardian
from parents and other family: Lots of books, some CDs, gift cards, loads of cosmetic and nice smelling things (I think my godmother bought out Sephora), a piece of carry on luggage which will make it's debut in Austin next month and lots of fun and practical stocking stuffers...
from friends: more books, a reed diffuser from Pier 1 Imports, funny magnets, earrings, a sake set, scarves (I wear them ALL the time), some joke gifts...
My favorite gifts that I gave: for my cousin- a framed photo of her dog that I took on Thanksgiving cause she loved it.
My 5 yr old niece's pink Patriots fleece pajamas and nephew's (aged 2) fleece Red Sox pajamas cause they look so cute in them
|Warrior Scroller
I got a new dvd player, 3 seasons of "24" (which I havent ever seen one ep of yet), pinks new cd, some gift cards and a few dvds.
|Scroll Desperado
cool jacket, Amy Sedaris's book on hospitality, I Like You, a framed aerial map of the bayou area where our family camp-house is, handmade quilted placemats, a shirt that says "i like grass" with a wild-eyed cow on it, pics of my niece & nephew, a clown Pez dispenser, an extremely, horribly evil porcelain clown that i call "the pastel pediphile", and a Dremel
are you sitting on the soap?
sometimes, you just have to say 'what the f...'
|Scroll Stalker
I was looking through that book at work and I got to the end where she has the "f*** it bucket"...I laughed so loud I people started looking at me.
|Scroll Guardian
Oh! And I got some new games! Apples to Apples (board game), a Survivor DVd game that I have not yet played, and Survivor Mad Libs . I may bring those last two to Texas w/ me....heeeee!
|Scroll Desperado
hell yeah..definitely the mad libs!
are you sitting on the soap?
sometimes, you just have to say 'what the f...'
|Scroll Stalker
Oooo I want to play the Survivor game! I have an idea, if you are up for it. You could mail it here before you head this way, we can play while you are here, then I can ship it back. How's that sound?
***Edited to say that I am not a complete idiot, I was just excited and posted a reply prior to reading the entire post.***
|Besotted Scroller
just remember we're laughing with you
|Scroll Desperado
not me...i'm laughing at you.
thanks, i needed that.
are you sitting on the soap?
sometimes, you just have to say 'what the f...'
|Besotted Scroller
that's cuz i'm nicer
|Scroll Guardian
I can pack the game. It's small- the size of a DVD or video game. The instructions must be on the dvd. I still have not opened it.
|Besotted Scroller
okay lila is nicest
I didn't get these because of some greedy bastard on Amazon.com, but it was the thought that counted. I almost got Wonderman and The Secret Life of Walter Mitty on DVD
|Scroll Desperado
A Danny Kaye fan? Hmmm, curiouser and curiouser...
Why is that so curious? The man was a comedic genius!
|Scroll Desperado
Yes, he was. Hard to find Danny Kaye films on dvd these days. Still, it's not that which makes me curiouser and curiouser about the coincidence of these posts.
|Scroll Obsessive
I got myself a Sodastream from mom, that both me and hubby loves, since we are Coke-addicts both off us. The Sodastream-Coke thing actually tasts just as good as the "real" thing.
I also got a Pandora-Bracelet. I wanted that for ages.
But the best thing off all was the doll that one of my best friends made me all her self. Really pretty to. It is a doll made to look like my favorite World of Warcraft character. A tauren girl. Beat that!
My LiveJournal: A look inside KSenas mind...
|Besotted Scroller
mom decided to get me a late gift.. of course now she wants my old one
i should go show it to brucy
Now I'm quite confused.
|Besotted Scroller
i believe that's the point
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Our paper titled "Staggered Boards and Private Benefits of Control" adds a new perspective to the ongoing debate about whether staggered (or classified) boards of directors lead to entrenchment. The novelty of the paper is focusing directly on private benefits of control by taking advantage of a new market-based measure of the value of voting rights, which is interpreted as a lower bound for private benefits.
In a firm with a staggered board, only a fraction (usually one-third) of the board members are up for election at an annual shareholder meeting. Thus staggered boards provide a potent anti-takeover mechanism by impeding potential contenders from obtaining the majority of board seats. Critics argue that insulating firms from the market for corporate control leads to entrenchment of the incumbent managers and reduces firm value. In contrast, proponents argue that staggered boards are a value-maximizing governance choice and increase firm value through board independence, management stability and resistance to hostile or opportunistic takeovers.
Identifying the effect of staggered boards on firm value is not straightforward, because the price of common shares incorporates both the value of expected future cash flows and the value of shareholder voting rights. Consequently, any change in the stock price can be due to a change in either the value of expected future cash flows or the value of voting rights (or both). Moreover, the value of voting rights reflects the private benefits of control that may be extracted from the firm. Therefore, drawing inferences about entrenchment in a firm by looking only at stock prices is complicated. Prior studies largely overlook this issue, in part due to the lack of a broadly applicable measure of the value of voting rights, and tend to infer about entrenchment indirectly by examining firm performance or governance outcomes.
We estimate the value of voting rights from option prices (hereafter, control premium), following the method introduced in Kalay, Karakaş, and Pant (2014).[1] In essence, the method captures the control premium by synthesizing a non-voting share of common stock using the option put-call parity relation, and comparing the price of the synthetic non-voting share to that of the underlying stock. The key insight for the method is that option prices reflect the cash flows of the underlying stocks, but not the control rights. An important advantage of using this new method is that it enables us to estimate the control premium for a large sample of firms, unlike other methods of estimating the value of control such as using dual-class stocks or trades of controlling blocks. Further, and more importantly, we believe our method is more suitable for studying corporate governance issues, particularly staggered boards. This is because firms with dual-class stocks or controlling blocks are subject to selection biases, and the control in such firms is already concentrated. Thus having staggered boards is arguably less relevant in insulating these firms further from market for corporate control. Under such circumstances, the applicability and usefulness of the other methods of estimating control premium are limited.
Analyzing US public companies over the period 1996 to 2011, we find that control premium is higher for firms with staggered boards. This result holds after controlling for firm characteristics such as total assets, leverage, book-to-market ratio, firm age, insider ownership, R&D expenditures, ROA, and CAPEX, and for time invariant unobserved firm characteristics through the inclusion of firm fixed-effects. Focusing solely on the sample of 163 (33) firms de-staggering (staggering) their boards and in the years immediately before and after these changes in board structure, we find that firms de-staggering (staggering) their boards experience a 54% (11%) decrease (increase) in their control premium. These results are stronger for the de-staggering cases, compared to the staggering cases. This may be due to two possible reasons. First, we observe de-staggering of boards more often than staggering, and therefore our sample is larger for the former cases. Second, the de-staggering cases are arguably less subject to reverse causality concerns. This is because staggering the board might indicate an already entrenched management, whereas de-staggering tends to happen due to the pressure of dissenting/activist shareholders.
To mitigate the potential endogeneity concerns in the relation between staggered boards and the value of control rights, we use a quasi-natural experiment. This experiment is based on two court rulings in 2010 with opposite decisions on the effectiveness of staggered boards (Bebchuk, Cohen, and Wang (2011)).[2] These rulings were made during and in response to the takeover battle between Airgas Inc. (target) and Air Products and Chemicals, Inc. (acquirer). The Chancery Court's ruling on October 8th, 2010 (event #1) allowed for a shareholder-adopted bylaw to move up the date of the next calendar year's annual meeting to any date within that calendar year. This would allow the acquirer company to accelerate obtaining the majority of the board seats in the target company. The Chancery Court's ruling weakened (but did not eliminate) the effectiveness of staggered boards. On November 23rd, 2010 (event #2), Supreme Court reversed the ruling of Chancery Court on the basis that changing the date of annual meetings would implicitly and unfairly shorten the tenure of some board members. Hence, the second ruling essentially nullified the effects of the first ruling observed on October 8th. This decision, however, was somewhat anticipated by the market, and hence the reversal of the effects could have spread before the actual announcement of the decision. Bebchuk, Cohen, and Wang (2011) document a positive (negative) stock market reaction to the first (second) ruling for firms with staggered boards.
Using the above-mentioned quasi-natural events, we find that firms with staggered boards experience a decrease (increase) in their control premium after event #1 (event #2). Note that this effect is likely to be causal due to the exogenous court decision affecting all firms with staggered boards. The changes for event #1 are statistically stronger compared to those for event #2. This is not surprising given that event #1 was much more unanticipated.
Finally, we test whether the market reaction to the court rulings is indeed associated with the control premium. We find the changes in control premium around event #1 to be significantly and negatively associated with the cumulative abnormal returns (CARs) around event #1. This further suggests that the value of control rights is a determining factor for the positive market reaction to the de-facto weakening of the effectiveness of staggered boards due to the court ruling. Our finding of a negative relation between the stock returns and the changes in control premium around event #1 is noteworthy. This is because, ceteris paribus, if the control premium of a stock increases (decreases), the stock returns would increase (decrease) as well – this would bias against us finding negative correlation between the stock returns and changes in control premium. The relation between event CARs and the change in control premium around event #2 is not significant. Again, this is not surprising given that the Supreme Court's overruling was somewhat more anticipated.
Taken together, our results suggest that, consistent with the entrenchment view, staggered boards are perceived by the market on average as a value-reducing rather than value-maximizing corporate governance choice.
[1] See Avner Kalay, Oğuzhan Karakaş, and Shagun Pant, The Market Value of Corporate Votes: Theory and Evidence from Option Prices, 69(3) J. Fin. 1235 (2014).
[2] See Lucian A. Bebchuk, Alma Cohen, and Charles C.Y. Wang, Staggered Boards and the Wealth of Shareholders: Evidence from Two Natural Experiments, (available at http://ssrn.com/abstract=1706806) (June, 2011).
The preceding post comes to us from Oğuzhan Karakaş, an Assistant Professor of Finance at Boston College and Mahdi Mohseni, an Assistant Professor of Finance at the Texas A&M University. The post is based on their article, which is entitled "Staggered Boards and Private Benefits of Control" and available here.


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Saving Private Ryan
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Steven Spielberg directed this powerful, realistic re-creation of WWII's D-day invasion and the immediate aftermath. The story opens with a prologue in which a veteran brings his family to the American cemetery at Normandy, and a flashback then joins Capt. John Miller (Tom Hanks) and GIs in a landing craft making the June 6, 1944, approach to Omaha Beach to face devastating German artillery fire. This mass slaughter of American soldiers is depicted in a compelling, unforgettable 24-minute sequence. Miller's men slowly move forward to finally take a concrete pillbox. On the beach littered with bodies is one with the name "Ryan" stenciled on his backpack. Army Chief of Staff Gen. George C. Marshall (Harve Presnell), learning that three Ryan brothers from the same family have all been killed in a single week, requests that the surviving brother, Pvt. James Ryan (Matt Damon), be located and brought back to the United States. Capt. Miller gets the assignment, and he chooses a translator, Cpl. Upham (Jeremy Davis), skilled in language but not in combat, to join his squad of right-hand man Sgt. Horvath (Tom Sizemore), plus privates Mellish (Adam Goldberg), Medic Wade (Giovanni Ribisi), cynical Reiben (Edward Burns) from Brooklyn, Italian-American Caparzo (Vin Diesel), and religious Southerner Jackson (Barry Pepper), an ace sharpshooter who calls on the Lord while taking aim. Having previously experienced action in Italy and North Africa, the close-knit squad sets out through areas still thick with Nazis. After they lose one man in a skirmish at a bombed village, some in the group begin to question the logic of losing more lives to save a single soldier. The film's historical consultant is Stephen E. Ambrose, and the incident is based on a true occurance in Ambrose's 1994 bestseller D-Day: June 6, 1944. ~ Bhob Stewart, Rovi
Product Details
Release Date
MPAA Rating
R -- Restricted
2 hours, 49 minutes
- Dolby Digital w/ sub-woofer channel
- USA & territories, Canada
Video Features
- Exclusive message from Steven Spielberg
- "Saving Private Ryan: Into the Beach"
- Two theatrical trailers
- Production notes
- Cast and filmmakers' bios
Number of Discs


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ANSO Web Camera Systems is an extension of ANSO (Aussie-Net Solution Online). We are web development specialists focused on providing cutting edge open source dynamic web platforms and extended web solutions.
We are the developers of innovative solar powered webcam and IP camera solutions for extreme conditions.
All of our web camera systems are developed, built and configured by Australians in Australia. We take great pride in hand crafting our systems to make them as reliable and hardy as possible.
As a complete package, our web development skills allow us to not only setup camera systems to save images to the web, but we also specialise in providing web platforms that receive the images, catalogue and archive the images, as well as displaying the images to the web in a live environment for easy viewing by end users.
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text:
The objective of this program is to provide the students with
training in One Health and bilingual (Spanish/English) shadowing
and/or research experience at the University Pompeu Fabra, or the
Universitat Autónoma in Barcelona, Spain. Studies will take place
at the School of Medicine (UPF) and the practicum will be either in
Primary care centers for those interested in human medicine, or,
for those interested in veterinary medicine, at veterinary clinics
or the school of veterinary medicine in Barcelona.
Students will be placed in primary care physician practicums or
vet clinics (for pre-vet med students) that will be linked with a
Texas A&M BIMS 485 directed studies credit for 3 credits. 3 credit hours of tuition/fees
paid to Texas A&M University are not included in the program
fee. A letter grade will be awarded for the 3-credit hour
course and factor into the Texas A&M GPA. - 2014 Syllabus
Texas A&M University • Website by CVM Communications • Website Feedback • Site Policies • Sitemap • Employment • Contact Us


text:
Fishing Tackle Enquiries
01656 722448
Hunting & Shooting Enquiries
01656 720807
Click here to find out our delivery rates
Seen an item advertised cheaper elsewhere? We'll match it!
Product Weight: 1.00 KGS
Deben Extreme Precision Bipod Swivel Tilt Lever
Fishing Tackle Shop
01656 722448
Hunting & Shooting Shop
01656 720807
Pay online securely with Sage pay
Keen's Tackle & Guns, 117/119 Bridgend Road, Aberkenfig, Bridgend, CF32 9AP
©Keen's Tackle & Guns. All Rights Reserved. Hosting by Big Commerce


text:
Snow parks worldwide
Ski resorts with the best fun parks/snow parks worldwide - Snow parks incl. halfpipes and fun slopes worldwide
431 test reports
Best rating:
5 out of 5 stars
Evaluated by Skiresort.info, the world's largest evaluation and test portal for ski resorts.
Click here for rating process info
Top fun parks worldwide
- Worldwide – limit to
Continents: 1. Europe , 1. North America , 1. Asia , 4. Africa
Countries: 1. Austria , 1. USA , 1. Switzerland , 1. Canada , 1. Italy , 1. France , 1. Norway , 1. Germany , 1. Sweden , 1. Finland , 1. Andorra , 1. Japan , 13. Netherlands , 13. Czech Republic , 13. Spain , 13. Slovakia , 13. Russia , 13. Bulgaria , 13. Belgium , 13. Lithuania , 21. Poland , 21. United Kingdom , 21. United Arab Emirates , 21. Iceland , 21. Liechtenstein , 21. Lesotho , 27. Denmark , 27. Qatar , 27. Mongolia
Mountain ranges: 1. Alps , 1. Rocky Mountains , 1. Pacific Coast Ranges , 1. Scandinavian Mountains (Scandes) , 1. Appalachian Mountains , 1. Pyrenees , 1. Japanese Alps , 8. Central Uplands of Germany (Deutsche Mittelgebirge) , 8. Carpathian Mountains (Karpaty) , 8. Black Forest (Schwarzwald) , 8. Caucasus Mountains , 8. Sudetes (Sudety)
There are large snowparks in both areas - the Nightpark in Hinterglemm and the Nitro Snowpark in... more
The Kitzsteinhorn has three snowparks and a superpipe measuring 150 metres long and 6.5 metres... more
There are 4 different areas in Arosa and Lenzerheide with snowparks for everyone's taste.more
There is a large fun park and a funline at the Steinplatte Winklmoosalm ski resort. The Snowpark... more
The Funzone Montafon is located on the Fredakopf (Grasjoch) in the Hochjoch section of the ski... more
The ski resort offers two first class snowparks in Obereggen. There is also a boarder cross course... more
Freestylers and snowboarders can choose from numerous snowparks in the SkiWelt Wilder... more
The Schöneben Snowpark will make snowboarders' hearts beat faster. The snowpark was opened during... more
There are several snowparks and funslopes in the ski resort of Val Gardena. Not forgetting a... more
The snowparks in the Hochkönig ski resort are located in Mühlbach and Maria Alm. The Blue Tomato... more
Kitzbühel has also established a first-class reputation for its snowparks. There is something to... more
Ischgl offers a very large and perfectly groomed snowpark and a Funline on the Idalp. In Samnaun,... more
Mayrhofen's Penken Park is one of the best and largest snowparks in Europe and there is also a fun... more
The Zillertal Arena offers first class snowparks and offers for adrenalin fans. The highlights are... more
There is a large snowpark with a boardercross course, wave runs and integrated fun slope at the... more
The Schilthorn offers a very good snowpark.more
Turracher Höhe has one of the most extensive selections of fun mountain attractions in Austria,... more
There are some excellent snowparks in the Skiarea Campiglio Dolomiti di Brenta... more
The Betterpark at the Olperer tow lifts at about 3200 m above sea level is famous in the... more
The ski resort is a true paradise for boarders and freestylers. There are 5 terrain parks, a... more
Corvatsch Park is one of the top snowparks in the Alps.more
Buttermilk Mountain offers great snowparks. The parks and the superpipe are groomed daily.more
The top class Swatch Snowpark Laax is located on Crap Sogn Gion. The snowpark is split into four... more
The Alpe di Siusi (Seiser Alm) snowpark is first class.more
In the ski resort of Stoneham, there is a large snowpark, the "Parc XL", with an Olympic halfpipe... more
There is just one classic snowpark within the entire 4-Mountain Ski Area, but the Superpark Planai... more
In Tandådalen, there is a huge snowpark with a halfpipe and a Big Air arena. A beginners' park in... more
In the autumn and spring, the Snowpark on the Stubai Glacier is one of the largest and most varied... more
The Funpark Funtaklaus is one of the best snowparks in the Alps. There is also the Dino-Fun-Line... more
The Superpark Dachstein at the Hunerkogel tow lift is available for snowpark fans in spring and... more
At the snowpark and fun slope in Alta Badia, both beginners and advanced riders will be satisfied.... more
The Flachauwinkl/Kleinarl ski resort is an Eldorado for snow park fans. It offers different park... more
The Sunshine Village ski resort features three first-class snowparks.more
Sun Peaks features one of the largest snowparks in Canada. It stretches from the mountain station... more
The Kaunertal Glacier is well-known in the snowboarding scene. The season openings take place here... more
San Martino di Castrozza has two first class snowparks on the Alpe Tognola and on Col Verde. There... more
The large snowpark is located in Alpendorf on the Hirschkogel. The funslope is on the Sonntagskogel... more
Freestylers and snowboarders will be pleased with the very good snowparks here. Grandvalira offers... more
The Mount Seymour ski resort offers four first-class terrain parks featuring all difficulty levels.... more
Grouse Mountain offers three first-class terrain parks featuring all difficulty levels.more
The Cypress Mountain ski resort offers four first-class terrain parks featuring all difficulty... more
Whistler Blackcomb offers 6 first class Nintendo Terrain Parks. Beginners and experts will find... more
Big White offers a first-class terrain park with a half pipe, super pipe and its own double... more
In Les 3 Vallées, there is a complete assortment of funparks with difficulty levels ranging from... more
Almost the entire "La Toura" sector of Les Deux Alpes is set up as a funpark at 2600 m:... more
The Snowpark Pitztal Glacier at the Mittelberg lift leaves no wish unanswered. There is also a long... more
The Oslo Vinterpark Tryvann definitely has something to offer as far as snowparks and halfpipes. In... more


text:
Welcome to Zeke Hailey's official web site. Zeke is the hero in a series of novels set on Mars. Here you can find out more about his adventures, the characters, Mars and contact the author, Ian C Douglas. Read chapter 1 from the Infinity Trap free HERE, and Gravity's Eye's prologue here. The Particle Beast (Book 3) launched in summer 2017. Ian is hard at work now, writing Electron's Blade, the 4th instalment and due late 2018.
Zeke lives in a future where every 15-year-old on the planet takes a psychic exam. The precious few who pass are sent to the Chasm on Mars, training to become Mariners. These are the enigmatic space travelers who pilot starships across the galaxy in an instant. The only problem being sometimes they don't come back.
Mars, although terra-formed, is rife with dangers. And what happened to the original Martians, who disappeared 2 billion years ago? They've left behind some very weird artifacts, capable of transforming the human brain. But even worse is the Spiral, a demon from the dawn of time….


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In a dusty theatre about to be demolished, a reunion of former "Weisman's Follies" members takes place.
Memories are exchanged and former routines resurrected. Amid these, the troubled lives of Buddy and Sally, and Ben and Phyllis unfold.
Stephen Sondheim's musical is an affectionate look back at an era long past, as well as an incisive exploration of relationships. It's also a challenging production to mount and Southwick Opera successfully met that challenge.
Strong direction and a fine cast ensured the complexities of the storyline and the presence of ghostly counterparts of younger selves were clearly understood.
There were superlative performances from the four principals - Tania Newton was heartbreaking with her two big ballads, while Karen Orchin fully captured the cynicism of the emotionally abandoned Phyllis in Could I Leave You. Raw emotion was never far away from the comic shell of Steve Emery's excellent Buddy.
The show's climax has Ben, sensitively played by Jim Apted, having a breakdown, but the full impact of this was lost due to him being swamped by overcrowded staging.
A couple of solo spots needed to be stronger, however, this was a most welcome revival of a great show.


text:
Using II Timothy 2:15 as the contributing force, we offer Sunday Life Groups for all ages, and opportunities of Bible Study on Monday mornings at 10am (Adults), and various age group studies on Wednesday evenings at 7pm.
"Study to shew thyself approved unto God, a workman that needeth not to be ashamed, rightly dividing the word of truth." II Timothy 2:15


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White Crib Boy Nursery
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As adjective, whiter, whitest
of the color of pure snow, of the margins of this page, etc
; reflecting nearly all the rays of sunlight or a similar light
light or comparatively light in color
(of human beings) belonging to a group marked by slight pigmentation of the skin, often of European descent
for, limited to, or predominantly made up of white people:a white neighborhood
pallid or pale, as from fear or other strong emotion:white with rage
silvery, gray, or hoary:white hair
snowy:a white Christmas
lacking color; transparent
(politically) ultraconservative
blank, as an unoccupied space in printed matter:Fill in the white space below
composed entirely of polished steel plates without fabric or other covering; alwite
wearing white clothing:a white monk
Older Use: Offensive
decent, honorable, or dependable:That's mighty white of you
auspicious or fortunate
morally pure; innocent
without malice; harmless:white magic
(of wines) light-colored or yellowish, as opposed to red
(of coffee) containing milk
As noun
a color without hue at one extreme end of the scale of grays, opposite to black
A white surface reflects light of all hues completely and diffusely
Most so-called whites are very light grays: fresh snow, for example, reflects about percent of the incident light, but to be strictly white, snow would have to reflect percent of the incident light
It is the ultimate limit of a series of shades of any color
Compare black (def )
a hue completely desaturated by admixture with white, the highest value possible
quality or state of being white
lightness of skin pigment
a person with light-colored skin, often of European descent
a white material or substance
the white part of something
a pellucid viscous fluid that surrounds the yolk of an egg; albumen
the white part of the eyeball:He has a speck in the white of his eye
white or nearly white clothing, as in tennis whitestop-grade white flour
white wine:Graves is a good white
a type or breed that is white in color
Usually, whites
a blank space in printing
(initial capital letter) a hog of any of several breeds having a white coat, as a Chester White
any of several white-winged butterflies of the family Pieridae, as the common cabbage butterflies
white fabric
the outermost ring of the butt
an arrow that hits this portion of the butt
the central part of the butt or target, formerly painted white but now painted gold or yellow
a target painted white
Chess, Checkers
the men or pieces that are light-colored
(often initial capital letter) a member of a royalist, conservative, or reactionary political party
As verb (used with object), whited, whiting
to make white by leaving blank spaces (often followed by out)
to whiten (areas of artwork) in retouching preparatory to photoengraving (often followed by out)
to make white; whiten
As Verb phrases
white out, to cover (errors in copy) with a white correction fluid
to censor, as by obliterating words or passages with white ink
As Idioms
bleed white, Informal
to be or cause to be deprived of all one's resources:Dishonesty is bleeding the union white
in the white, in an unfinished state or condition, as furniture wood that has not been stained or varnished
As noun
a child's bed with enclosed sides
a stall or pen for cattle
a rack or manger for fodder, as in a stable or barn
a bin for storing grain, salt, etc
a translation, list of correct answers, or other illicit aid used by students while reciting, taking exams, or the like; pony
a petty theft
a room, closet, etc
, in a factory or the like, in which tools are kept and issued to workers
a shallow, separate section of a bathing area, reserved for small children
any confined space
a house, shop, etc
, frequented by thieves or regarded by thieves as a likely place for burglarizing
Building Trades, Civil Engineering
any of various cellular frameworks of logs, squared timbers, or steel or concrete objects of similar form assembled in layers at right angles, often filled with earth and stones and used in the construction of foundations, dams, retaining walls, etc
a barrier projecting part of the way into a river and then upward, acting to reduce the flow of water and as a storage place for logs being floated downstream
a lining for a well or other shaft
one's home; pad
a set of cards made up by equal contributions from each player's hand, and belonging to the dealer
a cheap, ill-kept brothel
a wicker basket
British, Australian
lunch, especially a cold lunch carried from home to work and eaten by a laborer on the job; snack
As verb (used with object), cribbed, cribbing
to pilfer or steal, especially to plagiarize (another's writings or ideas)
to confine in or as if in a crib
to provide with a crib or cribs
to line with timber or planking
As verb (used without object), cribbed, cribbing
to use a crib in examinations, homework, translating, etc
to steal; plagiarize
(of a horse) to practice cribbing
As noun
a male child, from birth to full growth, especially one less than years of age
a young man who lacks maturity, judgment, etc
a grown man, especially when referred to familiarly:He liked to play poker with the boys
a son:Sam's oldest boy is helping him in the business
a male who is from or native to a given place
boys, (used with a singular or plural verb) a range of sizes from to in garments made for boys
a garment in this size range
the department or section of a store where these garments are sold
boys, military personnel, especially combat soldiers:Support the boys overseas
Disparaging and Offensive
a term used to refer to or address a man considered by the speaker to be inferior in ethnicity, nationality, or occupational status
a young male servant; page
(in India, China, Japan, etc
) a native male servant, working as a butler, waiter, houseboy, etc
an apprentice seaman or fisherman
As interjection, Also, oh, boy
an exclamation of wonder, approval, etc
, or of displeasure or contempt
As noun, plural nurseries
a room or place set apart for young children
a nursery school or day nursery
a place where young trees or other plants are raised for transplanting, for sale, or for experimental study
any place in which something is bred, nourished, or fostered:The art institute has been the nursery of much great painting
any situation, condition, circumstance, practice, etc
, serving to breed or foster something:Slums are nurseries for young criminals
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Meeting Rooms
Merewether Room
Our Merewether room is completely saturated in natural light, purpose built to accommodate up to 120 people theatre style, 80 classroom and 24 in a boardroom style. The Merewether room has an operable wall which can be split into two separate rooms within a few minutes – perfect for breakout sessions or concurrent meetings running adjacent to each other.
The room is newly built with sound proofing technology, state-of-the-art audio visual and individually controlled air conditioning to keep your delegates comfortable throughout the event.
The indoor and outdoorpre-function area can cater for your guests during morning tea,lunch and afternoon tea breaks and should you wish.
Boardroom 1 & 2
Our boardrooms are newly built and can accommodate up to 12 people in a boardroom style. Saturated in natural light, the boardrooms are the perfect place to meet with state-of-the-art audio visual facilities available as well as individual controlled air conditioning, a pre and post event space to allow for a successful day.


text:
Crimped Knitted Wire Mesh is a processed knitted wire mesh product used to create compressed units for filtration, shock mounts and flame arrestors.
The mesh can be formed via two methods:
1) Pulling through a custom made die to compress the material
2) Running the mesh through calendaring rollers to create a continuous strip of compressed mesh.
The finished product is available in densities (% metal by volume) ranging from 10% to 70%, depending on the performance needs of your application
Shaped Knitted Wire Mesh uses the natural resiliency of the material to maintain a desired shape in your application.
Because each loop acts as a small spring when subjected to tensile or compressive stress, knitted metal has an inherent resiliency.
If it's not distorted beyond its yield point, the material will resume its original shape when the stress is removed.
Even when it's compressed into a special shape, a high degree of resiliency is retained.
Varying the knitted structure, wire diameter, wire material and forming pressure used to create the part can control this characteristic.
Support:NINEWIN INTERACTION


text:
Manchester United have launched an audacious bid for the remains of Ferenc Puskás as the Old Trafford side continue to search for a striker to accompany the out of form Wayne Rooney.
Although unwilling to discuss values, it is understood that United have made a significant offer to the family of Hungary's greatest player, who passed away in 2006 aged 79.
Executive vice-chairman Ed Woodward said: 'I think it's an open secret that we've been looking for new striking options throughout the summer, but so far we've come up blank. Now we've gone through pretty much every single living player, and failed to convince Denis Law to come out of retirement, we've had to go to Plan C, which is to dig up Ferenc Puskás's remains and stick him in a United shirt'.
United were drawn by Puskas's incredible scoring record – 508 goals in 521 games for Budapest Honvéd and Real Madrid, as well as 84 goals in 85 internationals for Hungary – as well as the fact that he was buried rather than cremated.


text:
« Ask not what the world needs. Ask what makes you come alive… then go do it. Because what the world needs is people who have come alive. »
Quotes :
- "Commitment means that it is possible for a man… "Commitment means that it is possible for a man to yield the nerve centre of his consent to a purpose or cause, a movement or an ideal, which may be more important to him than whether he lives or dies." - Howard Thurman
- Megan Follows – makes the world understand "I think we grow up as girls having to deal with a lot of oppressive beauty myths. And Anne is a girl who fails by all standards of what is acceptable and beautiful. She's not pretty. She's not rich. She has no parents. But through sheer exercise of will she makes the world understand how beautiful she is. It's her specialness, her ability to transform…
- "To be alive at all involves some risk."… "To be alive at all involves some risk." - Harold Macmillan
- "When you realize you're alive, you can… "When you realize you're alive, you can live life!" - Chad Michael Murray


text:
Here's a collection of interview questions asked in DE Shaw interviews. We have collected these questions from various forums.And published here for helping our readers to achieve success.
- What is the difference between HTTP and HTTPS
- Discuss ACID properties of a database system.
- Given a table Employee with only one field: Names, report all names with multiple entries.
- Given two sequences s1,s2 and another sequence s3, find if s3 is formed by interleaving s1 and s2.[Example: s1:abcd s2:bcaa s3:abbccdaa].
- If a class B is inherited from a class A, B has a function foo which is also in A, how do you call foo function in A?
- If a class B is inherited public from a class A, what all the variables that can be accesses and those that cannot be.
- List out the additional features of C++ over C when the latter is already available as a good programming language?
- Can classes,protected variables or other features in C++ be implemented using C?
- Define Deadlock
- Given a multi-threaded program How can you make it run on a system that supports only a single thread execution?
- Difference between a const char * and char const *?
- What are the Differences between a reference variable and pointer variable in C++?
- What is a register variable and what are the limitations on it? What is an automatic variable?
- What are the Differences in memory allocation in array and pointer(stack and heap)?
- Find the missing element in a sorted array in most optimum running time (O(log n))
Have got some interview questions submit it here.So that we can help other candidates like you to land their dream job


text:
Whether it's a short business trips, an extensive corporate event, or a relaxing leisure vacation, Echelon's private jet charter service can provide you with exactly what you need. We offer only the finest private jet charter and management services.
Expanding your jet charter options beyond major airports affords you the luxury of choosing the most convenient location for your destination, saving your time and energy. Let us assist you in replacing the hassle of traveling with relaxation, enjoyment and peace of mind. In order to personalize your jet charter travel experience, we can provide a no-obligation consultation. A seasoned and knowledgeable executive jet charter consultant will choose the best-suited aircraft for your travel needs.
Call us today at 512-219-9447 to schedule a consultation for private jet charter services.


text:
Over the years, I crossed paths with many souls.
A little more than 800 of these souls ended up as my Facebook friends, a figure that I have yet to trim (in spite of the intention of doing so many times). Let's condense this further: Of these Facebook friends, I probably physically met about a few dozen over the past 12 months. I keep regular, or weekly contact with maybe a handful.
This is when the definition of friendship itself gets interesting. How do you define friends? By the loosest definition, all of my Facebook friends are my "friends". This is obviously putting a very low threshold to friendship.
How about defining friends as the people that I regularly meet over coffee or talk over Whatsapp with? If this is the case, maybe I only end up with having not more than 10 friends.
Well, truth is, there's no strict definition of what a friendship should be made of.
Personally, I think that I have, over the years, developed the understanding that everyone has a lot of things that they have to deal with every single day. As we morph into different persons and grow out of the former state we were in (humans live in the state of permanent transiency anyway), our priorities shift. We graduate from college and enter the working world, with its new challenges. We shift work place to another company, with its new environment, demands and challenges. Some of us are married, some even have a kid or two to call their own. Our priorities shift.
With the shift of priorities often comes the "drifting away" stage. There's a group of my friends that I used to meet up with once a week. This turned into once a month. Then once in a couple of months. Then occasionally.
Details aside, does "drifting away" means that one is not keen to keep his friendship? Not necessarily. Again, priorities change, so does the shape and form of the friendship. Because one is often surrounded by changing circumstances, it's understandable that he would adapt himself to the situation he is in at the moment. This is fact of life. We are all malleable beings.
So to me, at the end of the day, when all is said and done, what really matters is how you keep your friends in your mind. Once you have the idea etched in your mind that someone is worthy of your long-term friendship and connection, nothing, not even time and distance, can ruin the bond that you have with that person. This is how I define friendship nowadays. I don't need to see you every single week to remind myself that you are dear to me (well, a coffee session wouldn't hurt, of course, but we live in a busy universe).
I understand if you don't have as much time to spend with me as we used to.
But I want you to know that once you need me I am here. Once you need to talk, I am here. No awkwardness, no judgment, no patronising remarks, just myself, and my ears, ready to listen to your grouses, ready to say things as they are.
This is what real friendship is, to me. Not something that you need to be reminded of every single time, nor is it something that you need to physically commit to every week. It's the conscious understanding that whatever happens, you have someone's back, and someone has yours.
I'll be here to support you, and that's for sure.
Speak soon,


text:
|Mutation Type
|12,478,497 bp (GRCm38)
|Base Change
|T ⇒ A (forward strand)
|Gene Name
|EDAR (ectodysplasin-A receptor)-associated death domain
|5830469M23Rik, 1810032E07Rik
|Chromosomal Location
|12,472,632-12,520,438 bp (-)
|MGI Phenotype
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
PHENOTYPE: Spontaneous mutations may lead to a kinked tail, reduced fertility, abnormal respiration and sparse hair. Chemically-induced mutants may show developmental defects in teeth, hair and ectoderm-derived glands, reduced viability and fertility, respiratory disorders, and lipid, myelin and brain defects. [provided by MGI curators]
|Accession Number
|Amino Acid Change
|Isoleucine changed to Phenylalanine
|Institutional Source
|Beutler Lab
|Gene Model
|not available
|SMART Domains
Protein: ENSMUSP00000136158
Gene: ENSMUSG00000095105
AA Change: I105F
|Predicted Effect
|probably damaging
PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|Phenotypic Category
|Alleles Listed at MGI
All alleles(7) : Gene trapped(2) Spontaneous(2) Chemically induced(3)
|Lab Alleles
|Mode of Inheritance
|Autosomal Recessive
|Local Stock
|Last Updated
|2016-05-13 3:09 PM by Stephen Lyon
|Record Created
|Record Posted
|Phenotypic Description
The achtung phenotype was identified among G3 ENU-mutagenized mice. Achtung mice are characterized by a lack of fur behind the ears, an unusually stiff posturing of the tail, a crook at the tip of the tail, and abnormally short teeth. The animals resemble achtung2, gizmo or tabby/Sleek/downless mice, which have mutations in components of the EDAR signaling pathway. Achtung is allelic to gizmo.
|Nature of Mutation
The achtung mutation corresponds to an A to T transversion at position 813 of the Edaradd transcript on Chromosome 13, in exon 6 of 6 total exons.
The mutated nucleotide is indicated in red lettering, and causes an isoleucine to phenylalanine substitution at residue 105 of the EDARADD protein.
|Protein Prediction
Near its C terminus, EDARADD contains a death domain most similar to the death domain of MyD88 (35% sequence identity) (Figure 1) (1;2). The death domain was first identified in proteins involved in cell death induction, but is now known to function as a protein-protein interaction domain that mediates homotypic interactions with other death domain-containing proteins in order to propagate signaling. EDARADD binds to EDAR through such death domain interactions (1;2), but there appears to be no connection to apoptotic signaling from this pathway. Secondary structure prediction suggests that the EDARADD death domain has a primarily helical structure consistent with the helical regions of MyD88, FADD, p75 neurotrophin receptor, and Fas death domains (2). In its N-terminal region, EDARADD contains a TRAF-binding consensus sequence (Pro-Ile-Gln-Asp-Thr) which several non-death domain-containing TNFRs use to bind TRAFs 1, 2, 3 and 5 (3). Deletion of this sequence from EDARADD abolished its interaction with TRAFs 1, 2 and 3 in GST pulldown experiments (1). Human and mouse EDARADD are 80% identical overall, 96% identical in the death domain, and 100% identical in the TRAF-binding consensus sequence.
The achtung mutation results in the substitution of isoleucine 105 by phenylalanine. This residue is located at the N-terminal end of the death domain.
In situ hybridization in mouse tissue sections and whole-mount embryos detects Edaradd transcript in the basal layer of the epidermis (detected at postnatal day 2) and in epithelial cells during formation of hair follicles and teeth (detected at timepoints during mid-gestation) (1;2). Edar and Edaradd are coexpressed in these cell types. PCR analysis of cDNA from a panel of human tissues also detects coexpression of EDARADD and EDAR in pancreas, lung, thymus, prostate, testis and fetal skin (2). EDARADD is localized in the cytoplasm.
Mutations in EDA (4), EDAR (5) and EDARADD (1) cause hypohidrotic (or anhidrotic) ectodermal dysplasia (HED) in humans, as well as the Tabby (6;7), downless or Sleek (8), and crinkled (1;2) phenotypes, respectively, when the orthologous genes are mutated in mice. EDA, EDAR and EDARADD form the ligand, receptor and adaptor proteins, respectively, of a TNF-related signaling pathway specific to the development of so-called skin appendages, ectoderm-derived tissues including hair follicles, nails, teeth and exocrine glands in mammals.
Humans with HED typically have missing or sparse hair, missing or misshapen teeth, and absent or reduced ability to sweat. The reduced ability to sweat can cause hyperthermia, and results in a 30% mortality rate in children up to age 2 if the condition is not recognized (9). HED patients also have dry skin, eyes, airways and mucous membranes. Recently, ocular surface abnormalities (corneal lesions, inflammation) likely due to a lack of Meibomian glands were reported in both human HED patients and in Tabby mice (10;11). In humans, HED may be transmitted in an autosomal dominant (OMIM #129490), autosomal recessive (OMIM #224900), or X-linked recessive (OMIM #305100) manner. Human mutations of the X-linked EDA gene cause the majority of cases of HED. Male patients display a similar severity of phenotype, but heterozygous females with EDA mutations vary considerably in their symptoms due to varying levels of X-inactivation of the chromosome containing the mutated gene (12;13). Mutations in EDAR account for approximately 25% of cases, and can cause both autosomal dominant or recessive forms of HED (14;15). More rare EDARADD mutations (only two reported to date) also result in both autosomal dominant and recessive HED (1;16).
The four mutant mouse phenotypes Tabby (Tb), downless (dl), Sleek (Sl) and crinkled (cr), first reported in the 1950s, are characterized by lack of hair on the tail and behind the ears, lack of or abnormal morphology of incisors, a reduced number of vibrissae, and occasionally a kinked tail tip [(17-20) and reviewed in (21)]. Further study demonstrated that sweat glands (normally on the footpads), lacrimal, Meibomian and submandibular glands, and three of four types of mouse hair, are lacking in these mutants (21). As in humans, Eda is an X-linked gene in mice, and female Agouti (A) mice (normally with light/yellow hair) heterozygous for Tb, in contrast to hemizygous males, grow "tabby" colored fur (containing striping of variable degree) in a mosaic pattern, giving an appearance of transverse stripes of light-colored normal and dark hair (17;22). Loss of yellow pigment results in black hair in areas of skin containing the mutation in these mice (22). The underlying mechanism by which EDA affects pigmentation in A mice is unknown, and interestingly, no pigmentation defects have been reported in humans with EDA mutations. Cr mice, in addition to the phenotypes mentioned above, also have reduced viability (approximately 40% die before 10 days of age), are smaller than their wild type littermates, and sometimes develop respiratory disorders (23). Myelin abnormalities have been observed in the brains of cr mice, along with abnormal morphology and disordered layers in the cerebellum (24).
The ligand for EDAR, EDA, is a trimeric type II transmembrane protein (extracellular C terminus) with extracellular collagen and TNF domains (25). Cleavage by furin near the collagen segment releases soluble EDA to bind to EDAR (26). The gene encoding EDA is alternatively spliced to form several different transcripts [at least six in humans (27) and nine in mice (28)]. The two longest isoforms, EDA-A1 (391 aa) and EDA-A2 (389 aa), account for approximately 80% of the total EDA transcripts in mouse keratinocytes (28), and appear to be the functional forms (27). EDA-A1 and EDA-A2 differ by only two amino acids in the receptor-binding region of the protein: E308 and V309 are lacking in EDA-A2 (29). Strikingly, this two amino acid difference accounts for an absolute specificity of EDA-A1 and EDA-A2 for different receptors, EDAR and XEDAR, respectively (29).
Transfection of EDAR into 293E cells results in dose-dependent activation of NF-κB, and this response is drastically reduced when cells are transfected with mutant forms of EDAR containing the dl mutation or lacking the death domain (29;32). Overexpression of EDARADD also leads to NF-κB activation, but a mutant containing only the death domain blocks EDAR-dependent NF-κB activation (1;2). In vivo, loss-of-function mutations in the human or mouse IKK complex subunit IKKγ/NEMO result in HED (along with immunodeficiency) due to impaired NF-κB signaling (see panr2) (33;34). Furthermore, mice expressing a constitutively active form of IκBα develop a phenotype similar to Tb and dl (35). Together, the data suggest that the TRAF6/TAK1/TAB2 complex activates the IKK complex to phosphorylate IκB, which then releases NF-κB for translocation to the nucleus and activation of gene expression (1;31;33;36). Interestingly, although XEDAR signaling can also activate NF-κB in vitro (29), EDARADD does not serve as its adapter (2). XEDAR has no role in skin appendage development, as XEDAR-deficient mice have normal ectodermal-derived organs (37). TROY, the third EDAR family member, is also expressed in skin, including hair follicles, and activates NF-κB when overexpressed in 293T cells (38). An ENU-induced mutation of Troy in the mouse, which abolishes the ability of the corresponding recombinant protein to activate NF-κB in transfected cells, has normal hair follicles, hair shafts, hair type composition and sweat glands (39).
The downstream targets of EDAR signaling are reported to include proteins of the Wnt, Sonic hedgehog (Shh), bone morphogenetic protein (BMP) and lymphotoxin- β (LTβ) pathways, which were identified by comparative gene expression analysis of Tabby and wild type skin [reviewed in (39)]. The specific role of these pathways in skin appendage development and the mechanisms by which they interface with EDAR signaling are not well understood.
|Putative Mechanism
Isoleucine 105 lies at the N-terminal border of the EDARADD death domain. No structural data are currently available for EDARADD. However, two mutations causing one case of autosomal dominant (L112R) and one case of autosomal recessive (E142K) HED have been reported (1;16). Both residues are in the death domain. Both mutations blocked EDARADD binding to EDAR in coimmunoprecipitation assays using tagged proteins (16). When tested in NF-κB transactivation assays in HEK293 cells, EDARADD mutant proteins containing either mutation had a dramatically reduced ability to activate NF-κB, with EDARADD L112R showing only as much activity as the empty vector (1;16). It is predicted that the achtung mutation also abrogates the ability to bind EDAR and activate NF-κB, but these, and the ability to interact with downstream signaling partners such as TRAF6, TAK1 or TAB2, have not been tested.
|Primers cannot be located by automatic search.
Achtung genotyping is performed by amplifying the region containing the mutation using PCR, followed by sequencing of the amplified region to detect the single nucleotide change. This protocol has not been tested.
Primers for PCR amplification
Ach(F): 5'- TTCTGCACTATTCCAAGGAAGGAATCG -3'
Ach(R): 5'- CTGAAAACCTTAGGAGCAGGTACGC -3'
PCR program
5) repeat steps (2-4) 29X
Primers for sequencing
Ach_seq(F): 5'- TATTCCAAGGAAGGAATCGTGGAATC -3'
Ach_seq(R): 5'- ATCAGTTGGCCCACAGTC -3'
The following sequence of 670 nucleotides (from Genbank genomic region NC_000079 for linear DNA sequence of Edaradd) is amplified:
41683 ttctgcac tattccaagg
41701 aaggaatcgt ggaatcgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgacact
41761 tagatgatgt caccaaaatg gtaggaaaat aaaaggagta ttgctcgtgc gtgcgcgcgt
41821 gcgggaggtg cgcatggccc ctgggtaacc tgtgacctct ctgtcatcct gcaggtgtca
41881 gcagaaacca gccctgtaag gacgggaagg gcagctgctc ttgcccttcc tgctcccccc
41941 gggcccccac catcagcgac ttgctcaacg atcaggactt gctagatacg atcaggataa
42001 agctggatcc atgtcaccca accgtgaaga actggaggaa ttttgccagc aaatggggca
42061 tgccctatga tgaactgtgc ttcctggaac agaggcccca gagccccacg ctggagttct
42121 tattccgaaa cagccagagg actgtgggcc aactgatgga gctctgccgg ctgtaccaca
42181 gggccgatgt ggagaagatc ctgcgcaggt gggtggatga ggagtggccc caccggggac
42241 actccgacag ctccatgcac ttctagaatc ccctctcctc tggcattggc cctactgctc
42301 gttggaccag catggctcct gcggagagcg tacctgctcc taaggttttc ag
PCR primer binding sites are underlined; sequencing primer binding sites are highlighted in gray; the mutated A is shown in red text.
1. Headon, D. J., Emmal, S. A., Ferguson, B. M., Tucker, A. S., Justice, M. J., Sharpe, P. T., Zonana, J., and Overbeek, P. A. (2001) Gene defect in ectodermal dysplasia implicates a death domain adapter in development, Nature 414, 913-916.
2. Yan, M., Zhang, Z., Brady, J. R., Schilbach, S., Fairbrother, W. J., and Dixit, V. M. (2002) Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice, Curr. Biol. 12, 409-413.
3. Inoue, J., Ishida, T., Tsukamoto, N., Kobayashi, N., Naito, A., Azuma, S., and Yamamoto, T. (2000) Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling, Exp. Cell Res. 254, 14-24.
4. Kere, J., Srivastava, A. K., Montonen, O., Zonana, J., Thomas, N., Ferguson, B., Munoz, F., Morgan, D., Clarke, A., Baybayan, P., Chen, E. Y., Ezer, S., Saarialho-Kere, U., de la, C. A., and Schlessinger, D. (1996) X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein, Nat. Genet. 13, 409-416.
5. Monreal, A. W., Ferguson, B. M., Headon, D. J., Street, S. L., Overbeek, P. A., and Zonana, J. (1999) Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia, Nat. Genet. 22, 366-369.
6. Srivastava, A. K., Pispa, J., Hartung, A. J., Du, Y., Ezer, S., Jenks, T., Shimada, T., Pekkanen, M., Mikkola, M. L., Ko, M. S., Thesleff, I., Kere, J., and Schlessinger, D. (1997) The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains, Proc. Natl. Acad. Sci. U. S. A 94, 13069-13074.
7. Ferguson, B. M., Brockdorff, N., Formstone, E., Ngyuen, T., Kronmiller, J. E., and Zonana, J. (1997) Cloning of Tabby, the murine homolog of the human EDA gene: evidence for a membrane-associated protein with a short collagenous domain, Hum. Mol. Genet. 6, 1589-1594.
8. Headon, D. J. and Overbeek, P. A. (1999) Involvement of a novel Tnf receptor homologue in hair follicle induction, Nat. Genet. 22, 370-374.
9. Clarke, A., Phillips, D. I., Brown, R., and Harper, P. S. (1987) Clinical aspects of X-linked hypohidrotic ectodermal dysplasia, Arch. Dis. Child 62, 989-996.
10. Kaercher, T. (2004) Ocular symptoms and signs in patients with ectodermal dysplasia syndromes, Graefes Arch. Clin. Exp. Ophthalmol. 242, 495-500.
11. Cui, C. Y., Smith, J. A., Schlessinger, D., and Chan, C. C. (2005) X-linked anhidrotic ectodermal dysplasia disruption yields a mouse model for ocular surface disease and resultant blindness, Am. J Pathol. 167, 89-95.
12. Bartstra, H. L., Hulsmans, R. F., Steijlen, P. M., Ruige, M., de Die-Smulders, C. E., and Cassiman, J. J. (1994) Mosaic expression of hypohidrotic ectodermal dysplasia in an isolated affected female child, Arch. Dermatol. 130, 1421-1424.
13. Cambiaghi, S., Restano, L., Paakkonen, K., Caputo, R., and Kere, J. (2000) Clinical findings in mosaic carriers of hypohidrotic ectodermal dysplasia, Arch. Dermatol. 136, 217-224.
14. Chassaing, N., Bourthoumieu, S., Cossee, M., Calvas, P., and Vincent, M. C. (2006) Mutations in EDAR account for one-quarter of non-ED1-related hypohidrotic ectodermal dysplasia, Hum. Mutat. 27, 255-259.
15. van der Hout, A. H., Oudesluijs, G. G., Venema, A., Verheij, J. B., Mol, B. G., Rump, P., Brunner, H. G., Vos, Y. J., and van Essen, A. J. (2008) Mutation screening of the Ectodysplasin-A receptor gene EDAR in hypohidrotic ectodermal dysplasia, Eur. J Hum. Genet.
16. Bal, E., Baala, L., Cluzeau, C., El, K. F., Ouldim, K., Hadj-Rabia, S., Bodemer, C., Munnich, A., Courtois, G., Sefiani, A., and Smahi, A. (2007) Autosomal dominant anhidrotic ectodermal dysplasias at the EDARADD locus, Hum. Mutat. 28, 703-709.
18. Phillips, R. J. S. (1960) New mutant, Mouse News Lett 23, 29-30.
19. Sofaer, J. A. (1969) Aspects of the tabby-crinkled-downless syndrome. II. Observations on the reaction to changes of genetic background, J Embryol. Exp. Morphol. 22, 207-227.
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21. Mikkola, M. L. and Thesleff, I. (2003) Ectodysplasin signaling in development, Cytokine Growth Factor Rev. 14, 211-224.
22. Mouse Genome Database (MGD) Eda
23. Falconer, D. S., Fraser, A. S., and King, J. W. B. (1951) The genetics and development of "crinkled", a new mutant in the house mouse, J Genet 50, 324-344.
24. Theriault, L. L., Dungan, D. D., Simons, S., Keen, C. L., and Hurley, L. S. (1977) Lipid and myelin abnormalities of brain in the crinkled mouse, Proc. Soc. Exp. Biol. Med. 155, 549-553.
25. Mikkola, M. L., Pispa, J., Pekkanen, M., Paulin, L., Nieminen, P., Kere, J., and Thesleff, I. (1999) Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion, Mech. Dev. 88, 133-146.
26. Elomaa, O., Pulkkinen, K., Hannelius, U., Mikkola, M., Saarialho-Kere, U., and Kere, J. (2001) Ectodysplasin is released by proteolytic shedding and binds to the EDAR protein, Hum. Mol. Genet. 10, 953-962.
27. Bayes, M., Hartung, A. J., Ezer, S., Pispa, J., Thesleff, I., Srivastava, A. K., and Kere, J. (1998) The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats, Hum. Mol. Genet. 7, 1661-1669.
28. Hashimoto, T., Cui, C. Y., and Schlessinger, D. (2006) Repertoire of mouse ectodysplasin-A (EDA-A) isoforms, Gene 371, 42-51.
29. Yan, M., Wang, L. C., Hymowitz, S. G., Schilbach, S., Lee, J., Goddard, A., de Vos, A. M., Gao, W. Q., and Dixit, V. M. (2000) Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors, Science 290, 523-527.
30. Naito, A., Yoshida, H., Nishioka, E., Satoh, M., Azuma, S., Yamamoto, T., Nishikawa, S., and Inoue, J. (2002) TRAF6-deficient mice display hypohidrotic ectodermal dysplasia, Proc. Natl. Acad. Sci. U. S. A 99, 8766-8771.
31. Morlon, A., Munnich, A., and Smahi, A. (2005) TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd, Hum. Mol. Genet. 14, 3751-3757.
32. Kumar, A., Eby, M. T., Sinha, S., Jasmin, A., and Chaudhary, P. M. (2001) The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A, J Biol. Chem. 276, 2668-2677.
33. Doffinger, R., Smahi, A., Bessia, C., Geissmann, F., Feinberg, J., Durandy, A., Bodemer, C., Kenwrick, S., Dupuis-Girod, S., Blanche, S., Wood, P., Rabia, S. H., Headon, D. J., Overbeek, P. A., Le, D. F., Holland, S. M., Belani, K., Kumararatne, D. S., Fischer, A., Shapiro, R., Conley, M. E., Reimund, E., Kalhoff, H., Abinun, M., Munnich, A., Israel, A., Courtois, G., and Casanova, J. L. (2001) X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling, Nat. Genet. 27, 277-285.
34. Makris, C., Godfrey, V. L., Krahn-Senftleben, G., Takahashi, T., Roberts, J. L., Schwarz, T., Feng, L., Johnson, R. S., and Karin, M. (2000) Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti, Mol. Cell 5, 969-979.
35. Schmidt-Ullrich, R., Aebischer, T., Hulsken, J., Birchmeier, W., Klemm, U., and Scheidereit, C. (2001) Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices, Development 128, 3843-3853.
36. Schmidt-Ullrich, R., Tobin, D. J., Lenhard, D., Schneider, P., Paus, R., and Scheidereit, C. (2006) NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth, Development 133, 1045-1057.
37. Newton, K., French, D. M., Yan, M., Frantz, G. D., and Dixit, V. M. (2004) Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency, Mol. Cell Biol. 24, 1608-1613.
38. Kojima, T., Morikawa, Y., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Senba, E., and Kitamura, T. (2000) TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles, J Biol. Chem. 275, 20742-20747.
39. Cui, C. Y. and Schlessinger, D. (2006) EDA signaling and skin appendage development, Cell Cycle 5, 2477-2483.
|Science Writers
|Eva Marie Y. Moresco
|Diantha La Vine
|Pia Viviani, Xin Du, Bruce Beutler


text:
Calendar Girls by Tim Firth
Performance Dates: 8th - 20th July 2013
A funny, sentimental and captivating play guaranteed to make you laugh and cry.
Main Characters:
Chris – 45+ A party animal. Fills silences and generates laughter. The centre of attention.
Annie – 45+ happy to let Chris lead but a bit more conformist. Great foil for Chris and vice versa
Cora – 35 to 40ish Needs to be confident enough to sing Jerusalem as a solo at the start of the play. Ability to play the piano is desirable. Great character; funny, resilient and a single parent.
Jessie – 60/70 The best teacher you ever had but don't cross her. A lover of life and brave with it.
Celia – 35+ More at home in Debenhams than the WI. A bit of a rebel.
Ruth – 40ish We see her on the floor, from where she picks herself up, to blossom in true self confidence. Brilliant scene with the make up artist in Act 2.
Marie – 50s. The WI is her world. It justifies her existence
John – (Annie's husband). A human sunflower. Not a saint.
Rod – (Chris's husband) Able to put up with Chris and give as good as he gets.
We will also need 2 youngish men in their 20's and two or three other women, one in her 20's and two in their later years for smaller but no less important roles.
Scripts and more details are available from David Underwood firstname.lastname@example.com
Auditions: Thursday 21 February and Tuesday 26 February at the Theatre 7.30pm
LOVERS Winners & Losers by Brian Friel
Performance Dates: 23rd May – 1st June 2013
Two linked plays, set in 1960's Ireland, about the hopes and disenchantments of love
Mag, 17, extreme in her enthusiasms
Joe, 17, earnest about life
(but you don't actually have to be 17 to play the parts…)
Andy, 50-ish, solid, decent, reliable
Hannah, late 40's, old maid till now, but with Andy warm and passionate
(Again, ages are flexible. Ideally, the same two actors are also the narrators in Winners)
Mrs Wilson, 60-70, Hannah's mother, sweet but controlling
Cissy Cassidy, Mrs Wilson's friend, full of pious platitudes
Scripts and more details are available from Brian Gilbert email@example.com
Particular pieces to look at:
Mag: page 19, Joe: page 42
Mag, Joe: pages 30, 31
Andy: page 52
Andy, Hannah: pages 61-63
Hannah, Andy, Mrs Wilson, Cissy: pages 65-67
Auditions: Thursday 21 February and Tuesday 26 February at the Theatre 7.30pm


text:
By now, hopefully you know that the goal of Metro Startup Launcher is to make it much easier for startup companies in the Louisville metro area to raise capital through equity crowdfunding. We also want to help lots of people in the Louisville area actually make money by investing small mounts in lots of startups: a strategy that statistically has proven to provide an average of 27% return on investment for angel investors in the United States.
Now that we have the monthly meetings rolling for both entrepreneurs and investors, I guess it should come as no surprise to anyone that startup entrepreneurs are starting to ask: OK, so how do I actually do equity crowdfunding for my company.
A lot of people around here still think that you start a business in your garage, you get in pitch contests, go to a bunch of networking meetings, and meet some rich guys who invest in your company. Next thing you know, you've got venture capital money, a super cool startup company office, and all your wildest dreams come true!
The problem is, around here, we have plenty of pitch contests, but not enough rich people to invest in startups. However, we do have 1.3 million people in the Louisville metro area, and equity crowdfunding is now legal.
We've all heard about crowdfunding, but how does it work? Let's talk about some of the specifics.
On October 30, 2015, the Securities and Exchange Commission voted to adopt "Regulation Crowdfunding" (Regulation CF). The rules went into effect May 16, 2016. Regulation CF allows a company to sell up to $1 million in company stock in any 12-month period.
Here are a couple of the amazing features about the Regulation CF exemption:
It allows anyone to invest in a company. The investors do not have to be "Accredited Investors" (a.k.a millionaires).
You can raise capital from an unlimited number of investors, and the number of investors do not count toward the current maximum number of investors allowed by a private company (2000 total, 500 non-accredited).
However, investments are limited in the following ways:
If either the annual income or the net worth of the investor is less than $100,000, the investor is limited to invest the greater of $2,000 or 5% of the lesser of his or her annual income or net worth.
If the annual income and net worth of the investor are both greater than $100,000, the investor is limited to 10% of the lesser of his or her annual income or net worth, to a maximum of $100,000.
The transaction must be made through a broker, or through a "funding portal." This is actually a good thing because the portals have made it pretty easy to run your fundraise.
The business must be incorporated in the U.S.
The business may not be an "investment" company (set up for the purpose of investing in another company).
The SEC requires that issuers provide certain information to investors through the intermediaries' platforms and to the SEC directly via a filing of Form C on EDGAR, the SEC's data handling system.
If a current offering plus previous raises amounts to $100,000 or less, the financial statements must be certified by the principal executive officer and accompanied by information from the company's tax returns (but not the tax returns themselves).
If current offer plus previous raises amounts to $100,000-500,000, the financial statements must be reviewed by a CPA.
If the current offer plus previous raises amounts to $500,000 or more, the financial statements must be audited by a CPA. However,
Released April 04, 2017


text:
We spent our 4th of July not with sparklers and hot dogs, but with our dear friends as they wed in the ornate, 800-year-old St. Thomas Church and then threw a shindig at a restaurant just under the Charles Bridge.
It was roasting outside... so maybe we'll call our Scottish groom and our Moravian bride cool as cucumbers as they looked fresh and full of love and light despite the hot temps. I, myself, was absolutely cooking in my little black dress.
Anyhow, isn't this just a feast for the eyes?! It was a bilingual ceremony.
Our friends caught each others' eyes at the school where BW and I work, but it was a couple of years before she asked him on a date. Well played.
After the ceremony, per Scottish tradition, we were led by bagpipes out of the church and through Mala Strana (the oldest part of Prague)...
At the reception venue, per Czech tradition, the couple cleaned up a broken plate together and fed each other soup. Our fetching newlyweds made even a large bib look good.
Music was provided by the Brownies, a fantastically jazzy group famous for the huge crowds they draw at weekend farmers' markets. The lead singer's voice is simply buttah, dahling.
It was a flawless night, all champagne toasts and duck páté and dance floor hijinx... and lots of love! (And air conditioning, thank goodness!)


text:
TL Series Bass Demo
Our friends at ESP Australia distributor CMI just created this terrific video to show your the sounds and vibes of the LTD TL Series basses, including the new TL-5SM and TL-4Z Fretless. These basses have a ton of excellent sonic character, and can be used in places where other basses simply wouldn't be right. They've available now from your ESP dealer.
7,564 total views - 42 month views