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By Karen Ring
The risk of getting cancer increases as you age due to multiple somatic mutations (meaning that you acquire the mutation rather than are born with it) that build up in certain cell populations over time. Hematological cancers, also known as "blood cancers" or "liquid tumors", affect the blood, bone marrow, and lymph nodes. Examples of hematological cancers include leukemia (abnormal white blood cells), lymphoma (abnormal lymphocytes), and myeloma (abnormal plasma cells).
Diagnosing blood cancers is relatively easy. Doctors can take blood samples from sick patients (instead of conducting invasive tumor biopsies) and look for abnormal cancer cells in the blood or genetically screen for cancer causing mutations. Already, scientists have identified numerous genes and mutations that may contribute hematological cancers. However, mutations in multiple genes are usually required to override the body's natural immune response against cancer. Age-related clonal hematopoiesis is also a culprit for increasing risk of blood cancer. Clonal hematopoiesis is the idea that as hematopoietic stem cells age, they can acquire somatic driver mutations and the resulting clonal expansion populations have an increased likelihood of acquiring further mutations that can cause cancer later in life (See Figure 1).
As with other cancers, the risk for getting blood cancers increases as you age. In fact, it's been reported that around 2% of elderly people over the age of 75 have large chromosomal abnormalities that put them at risk for blood cancers. Currently, there is no predictive test to determine whether a healthy individual will get hematological cancer later in life. However two separate studies led by Steven McCarroll at Harvard Medical School and Benjamin Ebert at Brigham and Women's hospital recently addressed this issue by looking for cancer risk factors in thousands of blood samples from young and old people that had not been previously diagnosed with blood cancer. Their results were published together in the New England Journal of Medicine last week.
Both groups reasoned that clonal hematopoiesis typically precedes cancer-causing chromosomal abnormalities. Therefore they surmised that identifying genes in which driver mutations cause clonal expansion could be useful in predicting who will get blood cancers later in life. To make a long story short, both groups found that older people had a higher chance (10% of people older than 65) of having a somatic driver mutation that could cause blood cancer compared to younger people (only 1% of those under 50). Further genomic analysis of clonal expansions from both studies determined that somatic mutations were found most frequently in the genes DNMT3A, TET2, and ASKL1. All three genes have been previously associated with hematological cancers. Because both studies had access to patient medical records, they also determined that having a somatic driver mutation significantly increased your risk of getting hematological cancer, and also elevated your risk of heart disease, stroke, and even death.
While results from these studies suggest that regular genomic screening of blood samples could enable early detection of blood cancers, both groups believe this idea to be premature. They point out that while 10% of elderly people have clonal hematopoiesis with somatic mutations, only 1% of these patients per year actually get cancer. Therefore these studies suggest that technologies should be further developed to identify "at risk" individuals by identifying clonal expansions and somatic driver mutations and to potentially prevent the onset of hematologic cancers.


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While you read why not listen to my album 'Electro Baroque' (all tracks are also available on iTunes using the link here)? Classical music using modern instruments:
or if you prefer to listen to my electro/techno album 'Studio Valiumm' here are the videos (also on iTunes using the link here):
More info about my music is at the dedicated website www.TRANSFORMATES.com
This week I would like to introduce you to the Bavarian market village of Neubeuern with its impressive castle or schloss (Schloß Neubeuern). Neubeuern is a particularly picturesque village and was voted as Germany's most beautiful village in 1981. The village is built around a hill, which has an amazing back-drop of the Austrian/German Alps. I have a particular affiliation with Schloß Neubeuern because my son, Pascal, went to the Gymnasium (Grammar school) there. This is a well-known German mixed-sex boarding school and being based in a castle has something of a 'Hogwarts' feel to it. Any young 'Harry Potter' fan will not need to be asked twice to become a student there!
Pascal jumped at the opportunity to leave home for the Neubeuern castle at the age of 12. Coincidentally his brother Alex, 6 years earlier, had attended another castle school, Schloß Traunsee, in the Austrian Lake district – I will try to feature this in a forthcoming article. OK so J.K. Rowling may have had a titsy bit of influence on the selection of the boy's educational establishments. I featured the boys in last week's blog which can be found here).
Let me explain where Schloß Neubeuern is. The castle sits upon a hill which is surrounded by the pretty village of Neubeuern in the south of Bavaria not far from the border which leads into the Austrian Tyrol. It lies about half way between Munich and Salzburg. Here is the Google map which you can expand to find the nearest Autobahns and Towns:
Driving from my weekend retreat I crossed over the river Inn on the short journey from Bad Feilnbach to Neubeuern. The river Inn runs parallel to the Inntall Autobahn which is one of the key transit routes through the Alps between Bavaria and Italy.
Wherever you travel in this region you are not far from staggering alpine views.
Some of the best views of the castle 'Schloß Neubeuern' can be enjoyed by driving towards Neubeuern from the Austrian direction. It stands proud at the top of its own hill surrounded by the immediate countryside which is relatively flat. All of my photographs are prepared in high-definition so if you would like to see more detail just click your mouse with the cursor over the picture. After viewing the photograph use the backward arrow on your search machine to return to this article.
In order to enter the village square at Neubeuern you must drive through one of two villages gates or 'Tors'. This only allow traffic to pass in one direction at a time so drive slowly. These small gates ensure that large lorries do not enter into the village square.
As soon as you enter the gate you will be struck by the impressive old buildings with their colourful Frescos.
Once you arrive at the market square you get a view of the castle towering over the village. It is possible to park in the square and the town council is currently considering how they can increase the number of parking spaces. This has caused quite a heated debate because one of the proposals would involve removing two old trees from the square; an issue that has divided the residents of the village. If you would like to read more (in German) about this subject a local press article can be found here (don't let it be said that http://www.ChrisDuggleby.com doesn't bring issues of major environmental importance to the World stage!).
From the market square you can get a close up view of the beautiful hanging gardens which flow down the cliff face from Schloß Neubeuern to the village.
The colours of the hanging gardens are complemented by the well stocked window boxes of the many individually painted buildings below.
Even the buildings without flower baskets are artistically painted. Some of the paintings depict historical events or stories like the one below.
At the opposite side of the square to the castle is the village church. In addition, the castle has its own church which is also worth a visit. This 'Schlosskapelle St. Augustin' has fine examples of Bavarian late Baroque Rococo architecture. If you would like to see a 360 degree sight-seeing tour of the schloss and the staggering sights from its grounds please visit the interactive tour from the school's website which can be found here. (it can take a while to load!)
Just to the back of the church you will find a couple of the village's picturesque restaurants. Many of the restaurants have garden terraces which allow customers to enjoy the amazing sights of the mountains and local countryside.
All around the village it is possible to catch views of the Alps which provide the perfect back-drop to this scenic masterpiece.
It is difficult to find a building without pretty hanging baskets and impressive fresco work.
The next one is one of my favourites.
After a great day enjoying one of Germany's most beautiful villages I departed through the old village gate, but not before sampling some of the delights from the village baker.
In my view Neubeuern with its Schloß is well worth a visit and I will certainly be coming back. I hope you like the pictures and please do not hesitate to let me know if you have any suggestions or recommendations using the comments box below.
Chris Duggleby.
If you are interested in other scenic articles I have prepared from the Alpine countryside please take a look at the following photo-blogs:
here (Spitzingsee or Spitzing Lake in the Bavarian Alps)
here (Bavarian Schwarzenberg or the Black Mountain in the Voralpen region)
here (Thiersee or Lake Thier in the Austrian Tyrol)
here (Bayrischzell: a Bavarian village with an impressive background), and
here (Achensee or Lake Achen: The largest lake in the Austrian Tyrol and one of its best kept secrets)
Alternatively you might like to read some of my interesting reviews of interesting news items taken from the local press (some with a touch of humour). To see these simply click over the titles below:
18th March 2014: Germany and Finland Joint Investigation: New Case of Sexual Cannibalism Including Self-mutilation (Castration) During Intercourse.
7th March 2014: Invasive Alien Species (IAS) Discovered in France – Potential for European Ecosystem Disaster
4th March 2014: 30,000 Year old giant virus found in the Siberian Permafrost and 'resurrected' – it is still infectious!
2nd March 2014: Wolves are better at learning from their 'pals' than dogs.Through domestication dogs have lost a capability that is key to success in the wild.
24th February 2014: NAZI Research into the use of Mosquitoes as Biological Weapons to Infect Allied Troops with Malaria.
24th February 2014: Ant Wars: Crazy Ants deploy Chemical Warfare against Poisonous Fire Ants and their Amphibious Craft.
9th March 2013: Insects getting hooked on psychoactive drugs – How plants take advantage of bees by giving them a caffeine buzz.
29th December 2012: Spreading diarrhea and vomit through the washing machine – The Norovirus propagator in our kitchen.
23rd December 2012: Lower Saxony puts naked winter sports event on ice for safety reasons following massive popularity of undressed ladies on sledges and fears of over exposure.
18th August 2012: How Bavarians and Austrians use their middle finger – Fingerhakeln: a men-only sport (did Arnold Schwarzenegger start training this way?).
4th August 2012: Alpine Cows are Fined 100 Euros by Judge for Ringing their Cow-bells too Loud (Steiermark Kuhglockenstraffe: die Kirchenglocken zunächst?)
28th July 2012: Naked Night Swimming in the Lakes Around Munich (costumes and towels are for wimps!)
28th July 2012: Naked In-line Skating in Dachau (Is this Germany's Preparation for a new Olympic Event? – Watch out Beach Volleyball!)
7th July 2012: Sexual Equality in the Black Forest town of Triberg: Men only parking spaces.
If you find these articles interesting why not visit the contents list of my Alpine Press page and take a look at some of the other reviews, just click on the link here.
Now prepare for an uplifting experience!

subset: commoncrawl


text: I am not sure how much I trust Fleming as a historian; she often seems to soften her assessment of the Romanovs' actions and beliefs, and her descriptions of Lenin seem deliberately snide. Not that she is, strictly, inaccurate in either case, but her writing does seem to have a slant. Still, for me it was a pretty good introduction to this period in Russian history. I knew the general sketch of what had happened, of course, but Fleming does a good job laying out the details—even when they are pretty complex, and might easily be convoluted in a lesser writer's hands. From a narrative standpoint, she chooses well which parts to devote close attention to and which to paint in broad strokes. What might have been either dry or overly romanticized ends up being neither.


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Views: 136
Hi Penelope. I guess you're right. If you're alive and experiencing life, how can current events not show up in your work?!
Penelope said:
Current events always find their way into my works, particularly the way business is done and how the same actions done by different peoples yield disparate results.
Thank you Gale. Keep me posted with your progress!
Gayle Bell said:
Yes Gerrence, I'm working on my shifter novel that I started 5 years ago. The protagonist is currently building a team in the 2nd draft to keep fighting the good fight in case she is vanquished; that is the only change I am making since that started with the novel. Have a productive time. Ashe.
You're quite welcome. I'd be interested in hearing more about the stories, when you get the chance. - Ryan
Gerrence George said:
Hi Ryan! You bring up some interesting points. Thanks for reminding me that stories that feature character being revealed through major obstacles will never truly go out of style. As long as the means of communication are made available, stories will have a place. Thanks for the response!
Ryan Hemphill said:
I definitely see your point and while I can empathize with your struggle (and its motives) I think that you have chosen this narrative (killing the protagonist) because it speaks to you.
I have had an internal struggle with a similar issue. I have a storyline I'm developing that deals with the civil war era and while using a "steampunk-esque" approach to science fiction alternative reality, it also dealt with history in a brutally honest manner.
The kind of manner that Texas educational textbooks tend to "exclude", "rewrite" and "whitewash", if you catch my drift.
But at the same time, the question came up of whether it was "my story to tell". I myself am not black - so do I have the right (or the privilege) of telling stories that "aren't my own", especially when they aren't particularly happy or 'clean', for that matter?
An example of this was how many black slaves were "institutionalized" (aka brainwashed by their existence) so much that leaving slavery was actually too great a cognitive dissonance for them to handle. It's a known fact that Harriet Tubman had, on more than one occasion, threatened to kill those who tried to turn back with a gun. I don't fault these people for wanting to turn back, despite the horrors of their existence. Human beings, all human beings, have a tendency to chose the devils they know than the freedoms which might exist in the unknown.
I guess the thing that I am exposing which might not be taken well is how "weak" most of us can be in the face of adversity and change - even when it is extremely clear what consequences we are paying for the failure to stand up. I also point out the cases where "standing up for your beliefs" may also result in literally driving you insane - and that your insanity is actually how you protect yourself from acknowledging your vulnerability to the realities of the world. It's not a flattering picture of humanity, to be certain, but I think there is some "hidden beauty" in the clarity I'm trying to portray, which is why I continue.
So - while you are dealing with a different issue, I'd say the answer is "yes, you should still do it."
You are going forward with open eyes and as a writer, isn't that really what you're supposed to be doing?
- Ryan


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Harryville Homers showed that they haven't lost focus on matters close to home as they prepare for their Junior Shield and Cup double-header.
Robert Duddy's side warmed up for their two deciders by thumping Saturday Morning League title rivals Ahoghill Thistle 5-0 in the Rainey Cup quarter-final on Saturday.
Meanwhile, All Saints Old Boys overcame a huge test of their title credentials by beating fellow challengers Carniny Rangers.
Harryville Homers 5 Ahoghill Thistle 0: The cup holders were in no mood to surrender their trophy and ran a lacklustre Thistle ragged.
Homers took an early lead when Alan Rainey skipped past David Drummond before centering for the on rushing Darren Campbell to open the scoring.
It wasn't a case of if but when the Harryville side would add to their total and Alan Rainey duly obliged in the second half. The on fire wide man fired in a well placed right footer to beat Stephen Watson for three nil.
Number four came courtesy of Gary Bonnes when he pounced on the loose ball in the box to sweep his effort into the net. Ahoghill keeper Stephen Watson produced a one man show to keep the score down but was unable to prevent Paul McNeill scoring a fifth and Homers' 200th competitive goal of the season.
Carniny Rangers 0, All Saints OB 1: A Gavin Burnside goal 15 minutes from time proved to be the winner in this top of the table clash which keeps alive Saints hopes of winning the Division One title.
Carniny fresh from their Top Four Trophy win the previous Saturday started the game bright as they looked to strike an early blow and they came close on 15 minutes when Zach Barr saw his shot tipped round the post by Brian Martin in the Saints goal.
Carniny almost took the lead on 65 minutes when the ball broke to Ryan Bamber 18 yards out and he tried to place the ball in the corner of the net, but Brian Martin did brilliantly to get a hand to the ball and knock the ball to safety.
It was Saints who got the breakthrough on 75 minutes. Alan Telford slipped in substitute Stephen Sexton whose shot deflected to Gavin Burnside and he bundled the ball over the line from close range for what proved the winning goal.
Seven Towers 2, FC Penarol 4: Penarol sealed a spot in the end of season playoffs with this hard fought win over fellow promotion chasers Towers.
Towers took an early lead when Gary Taggart split the defence for Chris Graham to score after only two minutes. Penarol got back into the game 10 minutes before the break when prolific striker Kenny Wright fired home.
Player Manager David Paul gave his side the lead a minute after the restart before Wright again found the net to make it 3-1 on 68 minutes.
Towers got a goal back two minutes later when two players making their first appearance of the season combined. Steven O'Neill crossed to the back post for Simon Murray to head home.
Penarol regained their two goal cushion five minutes later and sealed the win when Darren Fletcher got on the score sheet to clinch all three points.
Carniny Amateurs 5, Steadfast (Carniny won 9-0 agg): Heading into this game with a 4-0 lead from the first leg, Carniny missed a penalty on 24 mins but made amends only two minutes later when Adam Greene crossed in from the right for Shane McWilliams to force the ball home from inside the six yard box. The same player doubled their lead on 40 mins from a Ricky Hanna corner nodding home for his second.
Just after half time young Benji Agnew was introduced and injected some pace into the game and directed a header into the goal from a corner on the hour mark and only five mins later scored his second as he weaved in from the left to set up a right foot shot into goal. On 82 mins Scott Buxton finished the game off with Lloyd White winning the ball with a header in the middle of the park, where it was flicked on for Buxton to send in a lovely looping shot on the half volley.
Rainey Cup 3rd Round: Glenravel 4, Newpark Olympic 3 (AET); Carniny Rangers 3, Abbeyview 2.
Rainey Cup Quarter Final: Ahoghill Rovers 0, Raceview 0 (Ahoghill Rovers win 3-1 on penalties)
firmus energy Division One: Abbeyview 1 Ahoghill Thistle 2; Raceview 3 Glenravel 0; Ballykeel 0 All Saints OB 9 ; Clough Rangers 0, Harryville Homers 3.
Ace Cup 1st Round: Harryville Homers 4 Glenravel 2 (AET); Riverdale 0 Ahoghill Thistle 12.
firmus energy Division Two: Cushendall 3 Woodside 0; FC Penarol 3 Carnlough Swifts 5; Michelin 2 Sporting Ballymoney 2; Randalstown 3 Cloughmills 1; Seven Towers 8 Galgorm Blues 2; Cloughmills 2 Ahoghill Rovers 6; Cushendall 4 Waveney Swifts 1; Galgorm Blues 2 Sporting Ballymoney 5; Seven Towers 1 FC Penarol 4; Sporting Ballymoney 0 Cushendall 2; Waveney Swifts 4 Woodside 2.
George McAuley 1st Round: Waveney Swifts 0 Ahoghill Rovers 1
George McAuley Cup Quarter Finals: Michelin 0 Seven Towers 0 (Michelin win 3-2 on penalties); Randalstown 0 Carnlough Swifts 2
firmus energy BSML Division Three: Braid United 4 Wakehurst Star 2; Templepatrick 0 Cullybackey Olympic 8.
CGRSC Sammy Moore Cup 2nd Round 1st Leg: Braid United 3 St Comgalls 2
CGRSC Sammy Moore Cup 2nd Round 2nd Leg: St Comgalls 6 Braid United 2 (St Comgalls Won 8-5 on Aggregate)
firmus energy BSML Division Three: Southside Rangers 2 Northend & District 1
Tuesday 26th April, 6-45pm - Rainey Cup Quarter Final: Glenravel v All Saints OB (Cargan).
firmus energy Division One: Ballykeel v Abbeyview (Ballykeel); Riverdale v Ahoghill Thistle (Wakehurst 2); Raceview v Carniny Rangers (Broughshane).
Wednesday 27th April - Toals Co Antrim Junior Shield Final 7-45pm: Harryville Homers v Ballyvea (Seaview).
Thursday 28th April 6-45pm - firmus energy BSML Division One: Clough Rangers v Ahoghill Thistle (Clough).
Saturday 30th April 10-15 KO - Ace Cup Quarter Final: Newpark Olympic v Abbeyview (Forum).
firmus energy BSML Division One: Ahoghill Thistle v Carniny Rangers (Ahoghill); FC Moylena v Glenravel (Forum).
firmus energy BSML Division Two: Carnlough Swifts v Holywell; FC Penarol v Sporting Ballymoney (Connor); Michelin v Ahoghill Rovers; Waveney Swifts v Randalstown (Waveney 2).
CGRSC Sammy Moore Cup Semi Final 2nd Legs: Northend & District v Carniny Amateurs & Youth (Dunfane 1); St Comgalls v Ruby's Rovers.
firmus energy BSML Division Three: Steadfast v Southside Rangers (Galgorm).
Montgomery Cup Group A: Braid United v Templepatrick (Broughshane).
Monday 2nd May Irish Junior Cup Final 2.30pm KO: Rosemount Rec v Harryville Homers (Windsor Park).


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The Skegness Neighbourhood Policing Team are appealing for information after damage was caused to a wooden fence on Hudson Way in Skegness.
PCSO Dave Bunker reports that between 5.40pm and 5:45pm on Tuesday, February 24, the fence was damaged.
Anyone who may be able to identify the offenders should contact police on 101, quoting crime reference 10347.
Alternatively, call Crimestoppers anonymously on 0800 555 111.


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You'll be a big hit with your Memphis Tiger fan when you present this adorable Baby Fan Cake gift set. We only select the best "ingredients" by DHM Kids for our Officially Licensed gift cake.
Baby Fan Cake Ingedients
This product hasn't received any reviews yet. Be the first to review this product!


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11450 S Union Avenue is a $3,360,000 property on a 5.14 acre lot located in Jenks, OK.
Excellent Retail Pad sites ready to go. Will divide. High visibility along Highway 75 over 45,000 AADT. Access road frontage to Highway 75. Buy the land only or we will be thrilled to build your next project.
|Exterior Features
Fence - None
|Water Source
|Property Type
Vacant Land
|Property Sub Type
Commercial Lot
|School District
jenks - sch dist (5)
Tulsa Co Unplatted
Copyright 2019 Greater Tulsa Association of REALTORS. All rights reserved. The data relating to real estate for sale or rent on this web site comes in part from the IDX program. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified. The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing or renting. Data updated every 15 minutes.


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Date: 09/16/1999
Writer: D'Lyn Ford
LAS CRUCES--The New Mexico Works program will be holding a second Mini Job Fair Sept. 22 in Las Cruces to help welfare recipients move into the workforce.
At the fair, participants in the Temporary Assistance for Needy Families (TANF) program can receive job training and the opportunity for job placement.
The fair will feature Department of Labor representatives, computer training, General Education Development (GED) test training and Census Bureau representatives.
"The Census Bureau will be hiring 500 people, including numerous clerical people for Dona Ana County and 1,000 people for the region," said Ray Nieto, KRUX host for Oye Como Va, a radio program sponsored by New Mexico Works.
There also will be a forklift presentation. Luis Nolasco, instructor of the New Mexico Works program, will be representing the New Mexico Works Project Life Skills Program.
New Mexico State University's Cooperative Extension Service is helping New Mexicans make the transition from welfare to work. Extension and other agencies received grants from the State Department of Human Services Department to help implement the New Mexico Works Act of 1998.
Far goers can sign up in advance for a particular area of interest or indicate their interests at the fair.
Food stamp recipients will not be eligible for training, but can apply for jobs at the fair.
For more information, contact the New Mexico Works office at (505)523-7580.
© 2013 New Mexico State University Board of Regents
NMSU - All About Discovery!


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SO INFOTECH is a leading India based software development outsourcing company focused on delivering the best and most cost-effective solutions to our clients in areas such as e-finance, e-business and media.
We Provide Maintenance Services ("off sourcing") for companies ranging from the Global 2000 to promising startups Combining proven expertise in technology.
We excel in "round the clock" support and test solutions. In the current environment, customers are demanding more and more from their vendors. The bar has been raised in two essential areas of a product life cycle: QUALITY AND SUPPORT . Typically these are the two areas that are least paid attention to!
We have established ourselves in these two areas and have been helping companies deliver high quality applications and the highest levels of customer satisfaction via our test and support solutions. Our highly trained and experienced pool of engineers set world class standards in not just the technical aspects but also the business aspects of a company. We spend the time to understand your client base and tailor each solution to perfectly fit your needs and your client needs. We have been providing Support and Test Solutions for over 10 years. We take pride in the quality of service that we provide along with a cost effective solution with a hundred percent satisfaction guarantee!
We offer a bespoke combination of consulting, outsourcing, offshore and specialist services across all types of quality management, testing and certification activity.
These services are attuned precisely to making absolutely sure that your required business outcome meets time, cost and quality targets
Copyright ® 2003 Soinfotech.com


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Hezbollah leader Sheik Hassan Nasrallah promised thousands of supporters Thursday that they will eventually bring down Lebanon's Western-backed government, but the prime minister vowed to stand firm against protesters. It was the seventh day of street demonstrations by Hezbollah and other pro-Syrian parties aimed at pressuring Prime Minister Fuad Saniora to quit in a deepening political crisis threatening to tear southern spain apart.
The plans appear to be at the ready despite, "Video showing rebels launching chemical anxiety. Will Obama order strikes on Syria despite the fact that evidence points toward the FSA getting? Will this administration consider all evidence or will they plow ahead with the missile punches? Will they launch another war despite most Americans opposing intervention in yemen vox?
The game also has expansion boards and power plant packages. New boards include France, Central Europe, China and Korea, and each introduces interesting aspects into the game. For example, the transaction in which power plants are revealed on the inside China game reflect's the country's planned affordable. Similarly, there are 2 resource markets in Korea to reflect the separate North and South economies, and the North Korea resource market doesn't require uranium (right.).
Vladimir Putin received a worthwhile presentation at the NATO summit in Romania this 1 week period. The Russians were advised to be neutral associated with scheduled attack against Iran's nuclear centers. As usual, American "diplomacy" contains bribes and threats.
Rules of Engagement (2000)- Samuel B. Jackson stars as Colonel Terry Childers, a marine who is brought to court-martial on charges of disobeying the rules of engagement in a military incident at an american embassy in Sana'a, Yemen, resulting in slaughter several civilians by Childers' fellows. With the help of Col. Hayes Lawrence "Hodge" Hodges II, played by Tommy Lee Jones, he is found innocent.
James hates everyone except his nanny. Take a look at life through this brilliant and mischievous New York teen's eyes as he tries to figure out life and his place to their rear.
But suicide was against Jewish statute. So it was decided to get lots to see who would do the killing. Ultimately only passed away would upwards having to kill on his own.


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First of all, The Unborn Dead carries a sincere raw analog quality to it, as if the songs were recorded sometime in the nineties. In fact, one can't help but question whether or not these were songs recorded at some point back in the day to appear as b-sides for some other Sinister recording that never surfaced. Given how crisp the vocals can sound, and the fact that these seem to not have been released at some point, we're probably just looking at something recorded from an in-home studio, or mastered to sound on par with a studio in the nineties. Either way, the quality of the music itself will have fans of Death Metal in general without negative remark, as it easily bolsters the impact of these two covers.
Up first is the cover of Grotesque's "Ripped From the Cross". The early Death Metal sound and steady drum presence laced with an eerie atmospheric backdrop makes this one of the better versions out there. The twanging bass presence gives the music a little more bite, especially when the haunting guitar solo kicks in by the two-and-a-half minute mark prior to the very ominous grooves once more. And then there's the Novembers Doom track "My Agony, My Ecstasy" to take in. While the previous cut is catchy as hell with some rich, somewhat distant buzzing on the guitars that make the grooves all the more addicting, this one carries itself with a darker, gothic tone that, while on par with the original composition, sounds more akin to something My Dying Bride would turn out.
The Unborn Dead is a raw slab of seven-inch vinyl that is something devoted fans of Sinister will appreciate a lot more than just your casual every day listeners of the band. Both covers are done very well, and the raw audio quality often associated with the early nineties makes them feel all the more genuine. Of course, with a limited pressing of only two hundred and fifty official copies available, chances are good that if you miss out on this release, you'll end up paying insane amounts out of pocket or resort to blackmailing those who refuse to let their copy go. But if you're a loyal fan and can grab a copy at a fair price, The Unborn Dead is worth picking up.


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Eating the fall peas straight off the vine.
Lately we've been preparing for the change of seasons. Putting the gardens to bed, mulching them with mowed-up leaves, putting the garlic in the ground before it freezes… Cleaning the hoop house and planting…planting so much: several different types of lettuces, radishes, spinach, kale, specialty salad greens. And my husband taking down the few trees nearby the hoop house, trees who were casting unwelcome shadows down on the little seedlings within. And we have been cutting wood – so much of it; piling it up, getting ready to hunker down inside while snow storms blow, and we will be warm inside with the fire.
The mixture of these activities…putting to bed, covering up, gathering warmth, planting and coaxing growth within the protective walls of the hoop house…it all has had me thinking of the song we sang last year at the Advent Spiral Garden. It all just reminds me of the lyrics.
We are walking towards the light
All the stars are shining bright
All the earth is sleeping now
And all the trees are bare.
Now we have our own true light
And our face is shining bright
It will keep us safe and warm
Until we're home again
There is such comfort to be derived in this season, such coziness and personal warmth.
Isn't that beautiful? We were driving to homeschool ice skating the other day when we came upon that sight. Just breath taking. I am so thankful for the four seasons! Without which, I would miss out on so much beauty.
Ice skating…we are so fortunate! Our homeschool group gets together weekly for this activity. The kids have been having such a blast, even Lily…she wears the little double-bladed kind of skate that fits over street shoes. Super convenient!
Last week was full of Halloween activities…we went to a seasonal hayride/night hike at our local Audubon center, the kids went to Zoo Boo days at the zoo, there was a homeschool Halloween party, and trick or treating at Old Sturbridge Village. I can't believe we're almost into November. I feel like the first half of the year always drags by, and then August through January just flies!
I have been knitting and knitting, chipping away at the Christmas gifts, and also indulging in "cheat" knitting periodically (when the holiday knit-list seems too demanding!). I've knit all but one pair of Christmas socks, a cowl for my husband's mother, hats for several people, and also fun things…sweater/vest for Lily, mitts for Sophia's birthday, etc.
I always look forward to the end of the "knit-list" season, but this year hasn't been too stressful, I think because I started so early.


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Erwin Passport Offices
The following passport offices serve Erwin, Tennessee. Please select a passport office in Erwin for contact information, hours of operation, passport photo information and passport appointments.
- Unicoi County Clerk of Circuit Court
100 Main St.
Erwin, TN 37650
Handicapped Accessible
No passport photos available at this location
Passport photos available at a nearby location
- Tennessee Passport Offices


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Jane (Born April 1999)
Jane is fully sponsored!
Jane came to Fairfield in 2004 with her sibling Nation. They had been living in Harare. Jane would like to become a nurse. She is a happy child who loves to cook and knit. She does well at school and also enjoys volleyball.


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Don Jedinak 1970 Chevelle SS 396 4 Speed
A 1970 Chevelle SS 396 4 speed 2 buildsheet car. This was one of the many HRF project cars we used for filler work. They are always for sale as a completed car so check with us from time to time to see whats available from our Minnesota hot rod shop.


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Walk focuses on Alzheimer's education
The Alzheimer's Association's first-ever Walk to End Alzheimer's in Jacksonville is planned this weekend.
The walk will take place Saturday at Community Park.
Participants will complete a 2-mile walk and will learn about Alzheimer's disease, advocacy opportunities, clinical studies enrollment and support programs and services from the Alzheimer's Association. Participants will also join in a tribute ceremony to honor those affected by Alzheimer's disease.


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Phil Vassar
Who is he?
Phil Vassar is one of country music's truest triple
threats!! Before securing his own recording contract, he had already long been established as one of Nashville's most prominent
songwriters, having penned hits for the likes of Collin Raye ("Little Red Rodeo"), Tim McGraw ("My Next Thirty Years"), Jo
Dee Messina ("Bye, Bye," "I'm Alright"), and others. Having honed his piano skills since he was a young boy, Phil also tickles
those ivories like none other!! In 1999, he released his own debut single "Carlene," and has since enjoyed a consistent string
of hits, including "Just Another Day in Paradise," "American Child," "Six Pack Summer," "I'll Take That As a Yes," "Good Ole
Days," among others. "American Child" was the title track of his second album and plays like a mini-movie of Phil's life.
He mentions his older daughter, Haley, in the song and also featured her in the video for it.In 2005, Phil sat alongside
Poison frontman-turned-solo artist Bret Michaels and A & R expert and industry insider Anastasia Brown, and each week,
the three helped Nashville Star 3 contestants along on their musical journeys. He enjoyed it so much that he returned
as a judge for the show's fourth season. Three albums later, Phil has released his first greatest hits collection –
appropriately titled Greatest Hits, Volume 1 – featuring his current single "Last Day of My Life." This is a must-add
to any of Phil's "Phrends," as it not only features his own hits as a singer - it also features him singing songs he wrote
for others artists!! Most recently, he also taped a television special for GAC called Piano Man in a Guitar Town; it
continues to gain positive feedback from industry personnel and fans alike. Phil came to Nashville to be a singer. In the
process, he also discovered his knack for writing great songs. These days, he's getting to do both!
What has Phil been up to?
Phil's Greatest Hits Volume 1 album sold over
64,000 copies in its first week, earning the country singer-songwriter his highest scanning debut at #2 on the Billboard Top
Country Albums Chart and #10 on the Billboard Top 200. Greatest Hits Volume 1, which features the Top 10 hit single
"Last Day Of My Life," scanned more than triple his previous highest first-week release, American Child, released in
2002!!Country Weekly cites the new disc as "... an example of how a compilation can actually redefine the artist."The
New York Times raves: "One great performance after another,... one of country music's most appealing voices."Phil
was recently photographed with his wife, Julie, and the family pets for a Nashville Lifestyles feature on "People and
Their Pets." CLICK HERE TO SEE A GREAT PHOTO FROM THAT SHOOT!!
Where can I buy his music?
ALL of Phil's albums are available by clicking on
each respective album cover!
Does he have an official site?
Absolutely! Check out Phil's NEWLY-relaunched site
at: http://www.PhilVassar.com!!
All articles, reviews, and artist feature
pages on this site are Copyright © 2001-2009 by STAR Country! and CAN NOT be copied, screen printed, or otherwise duplicated
or reproduced without explicit written permission from STAR Country!If you are an artist and need direct
links to any article, review, or the like on this site, please E-MAIL ESTELLA.
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Dec 30, 2016
Eric Anderson New President of PUC
Eric Anderson, who recently retired as president of Southwestern Adventist University, came home to Angwin and was promptly recruited to serve as interim president of Pacific Union College.
"Coming home" means Dr. Anderson served as a faculty member at PUC for 30 years, the fourth generation of his family to teach here. His grandmother, Agnes Caviness, was PUC's first baccalaureate graduate.
"Coming home" also means returning to Angwin as his hometown, to live on ancestral property built years ago.
Dr. Anderson's long academic career includes earning a Ph. D. at the University of Chicago, teaching history to thousands of PUC students in his classes, serving as a Fulbright lecturer in Greece and bringing his deep knowledge of history to the National Endowment for the Humanities.
Eric and his wife Loretta will resume living on familiar family property in Angwin where they had come to retire. He will serve as PUC president until the college Board has found a replacement for Dr. Heather Knight who recently retired.


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I've turn one of a new center category poor: How one author is gripping adult a apparition of prosperity
Liz Hoggard
02:52 EST, 13 Dec 2012
03:14 EST, 13 Dec 2012
For years I've had a repeated nightmare. I've left a poetic prosaic I've owned for a past 13 years, and changed into rented accommodation with a organisation of finish strangers.
My security are in boxes. I've mislaid any privacy. Something really wrong has happened in my life: we only can't work out what.
I wake, soaked in sweat, to find all as normal — books piled around my bed, Radio 4 playing.
Tags: 13 years, amazon, anxiety dream, assistant, August, avios, Bear, Caller, candle, cookery, course, current account, curt, Date, deposit, door, eBay, ex boyfriends, Favourite, floods, freelance, freelance writer, friendships, generation, generosity, ground, hardship, house, interest, Jigsaw, job, journalist, joy, keeping up appearances, Kind, life, middle-class, mind, mirror, money, month, mortgage, nectar points, newspaper, newspaper office, normal books, number, overdraft, parcels, pension, person, pity, planning, possessions, postgraduate, price, radio 4, recession, rent, salary, salary dentist, scheme, Selling, store, student books, tax, time, trouble, wasting, winter coat, year
For dentist with tyro debt, repaying is like pulling teeth
VACAVILLE, Calif. — His jaw clenched underneath a blue surgeon's mask, Opanin Gyaami jerks his right arm and pulls out a prize: a unkempt tooth of studious Larry Butler, also famous as state jail invalid J22312.
By a time he is done, Gyaami's smock and facade are speckled with a inmate's blood. He kindly pats Butler on a shoulder and wishes him well.
The 71-year-old dentist reports to a state jail in Vacaville day after day, prolonged past retirement age. He wishes he could have hung adult his cavalcade and forceps years ago, though he's still profitable off a tyro loan.
After borrowing
Article source: http://www.latimes.com/business/la-fi-student-loan-dentist-20121112,0,1544257.story?track=rss
Cosmetic Dentist in New Jersey Launches Mobile Website
U.S. Sues BofA for $1 Billion Over Mortgage LossesThe Wall Street Journal
The action, filed Wednesday in sovereign justice in Manhattan, seeks during slightest $1 billion in damages.
Article source: http://finance.yahoo.com/news/cosmetic-dentist-jersey-launches-mobile-090100965.html
Dina Lohan Reportedly $1.3 Million In Debt
The 50-year-old is in apocalyptic financial straits and during risk of losing to foreclosure her $1.1 million home in Merrick, N.Y., according to a New York Post. Dina Lohan reportedly has a $914,000 debt on a home, and owes another $302,000 since of a garnishment involving a former business associate. Some of her smaller debts embody delinquent bills to her divorce attorney, landscaper, dentist, and a BMW dealership.
The news about Dina Lohan's financial issues came to light after a now-infamous phone call Lindsay Lohan recently placed during a quarrel with her mom that was available and sent
Article source: http://www.ibtimes.com/dina-lohan-reportedly-13-million-debt-845881
'I'm Working Really Hard, though I'm Not Getting Ahead': The New Middle Class Trap
How "staying put" became a new "moving up" in U.S. economy
GRAND JUNCTION, Colo.–One day when John Sherry was 10 years old, his
parents picked him adult from propagandize and gathering to a Ford dealership. They
walked into a vast salon with Mustangs parked out front. He watched
his parents, conjunction of them college graduates, ink a paperwork to buy
a new, dark-green Taurus. Greg and Beth Sherry let their son pointer his
name during a bottom of one of a pages, only for fun.
John, who's
Article source: http://finance.yahoo.com/news/im-working-really-hard-im-150133570.html
Scranton workers onslaught with smallest salary pay
John Henehan has lived paycheck to paycheck for many of his life until recently, when he managed to save $2,000 to see his youngest son, an Army solider set to muster to a Middle East.
A lorry motorist with Scranton's Department of Public Works, Mr. Henehan, 50, put aside income to transport to Colorado to see his 20-year-old son, John, before a cavalry director leaves for Kuwait. He designed to cuddle his son, contend how unapproachable he is and tell him to stay safe.
"I wanted to contend goodbye in person," Mr. Henehan said.
After he had done a plans, black Friday hit
Article source: http://thetimes-tribune.com/news/1.1345122
6 foolish things we do with your money
Our attribute with income mostly feels like a bad romance. We adore income (and infrequently hatred it), it pulls on a deepest desires – and it creates us do some unequivocally foolish things. That's since a approach we hoop income is mostly about as receptive (or shall we say, irrational) as a initial crush. No matter how most we obsess about it, dream about it, and speak about it with a friends, when it comes to holding action, even smart, savvy women spin into finish ninnies. Don't trust us? Then maybe you've never done one of these stupid
Article source: http://ca.finance.yahoo.com/news/6-stupid-things-money-154846515.html
Father's Day: cheap, noted gifts for Dad
What's inside? Here are a questions answered in today's reader mailbag, boiled down to 5 word summaries. Click on a series to burst true down to a question.
1. Handling a vast gift
2. Free toothbrushes
3. Internet banking and destiny loans
4. Pieces of inspiration
5. Medical billing problems
6. Getting value from panini press
7. Toilet paper: peculiarity or price?
8. How most should we save?
9. Memorable though inexpensive Father's Day
10. Starting over with credit cards
Article source: http://www.csmonitor.com/Business/The-Simple-Dollar/2012/0611/Father-s-Day-cheap-memorable-gifts-for-Dad
BIG FLOP: Banks exclude to approve loans for My First Home scheme
KUALA LUMPUR, — Putrajaya's home tenure intrigue for low-income earners has come to a harsh hindrance only a year after it was launched as banks are reluctant to risk loans with monthly repayments value some-more than half a applicant's salary.
The My First Home intrigue launched by Datuk Seri Najib Razak final Mar offers 100 per cent financing to those aged next 35 and earning reduction than RM3,000 per month to squeeze homes value adult to RM400,000.
But Chinese-language daily Sin Chew Daily reported currently that a 30-year-loan for RM400,00 with a 4.3 per cent seductiveness rate would need a monthly
Article source: http://www.malaysia-chronicle.com/index.php?option=com_k2&view=item&id=29367:big-flop-banks-refuse-to-approve-loans-for-my-first-home-scheme&Itemid=2
12 Times That Being Cheap Will Cost You
Everyone loves a good deal, though going inexpensive during a responsibility of your health, home or reason is only plain stupid.
To get we on track, we've dull adult 12 of a many penny intelligent and bruise ridiculous moves we can ever make with your money.
Hitting a vending appurtenance for inexpensive snacks
Cheap snacks aren't assisting your wallet or waistline, says nutritionist Rania Batayneh of Essential Nutrition for You.
Bankrate.com found 72 million Americans could save on doctor's visits, health word premiums and groceries if they simply ate better. They competence even get a income boost.
Article source: http://finance.yahoo.com/news/12-times-that-being-cheap-will-cost-you.html
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I've been missing Morocco a lot lately.
My short 2-week visit to this stunning country back in 2011 was nothing short of incredible. At the end of it all, I wanted more. There was so much of this place that I wanted to see, experience, taste and breathe in.
Magical, magical Essaouira (Image: A screen grab from the video)
The Morocco I saw was an assault on all my senses. And I didn't want it to stop.
So, when I came across this wonderfully-made video by the highly-talented Vincent Urban and his team, I almost teared up. All those feelings of love and wonderment came flooding back.
There will be many detractors when it comes to Morocco. Sure, there will be the good and the bad, as in every other country. But I always believe that it's up to us as travellers to find the magic in the places we visit; to see beyond the words and opinions of others.
Morocco is one such place where magic abounds. It is nothing short of intoxicating. And I cannot wait to return someday.


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DVR can be described as a black box car use, all has to start the engine and then can video video, through high-definition camera photography, the image and voice record completely, vehicle driving when the accident happened malik proposed evidence, protect the rights of drivers themselves. And DVR GS20 is a can satisfy all requirements of the owner of vehicle traveling data recorder, high-definition derived from the most professional design and manufacture.
DVR GS20 supports 500 w pixels, 960*240 FULL hd recording, a 2.7 -inch screen to watch, even with HDMI hd output port. When using a HDMI output function, can be high-definition video output to the on-board display screen or on a computer terminal in time, convenient for the user at any time to watch. DVR is the most important is the high resolution and excellent image quality, whether it is day or night, GS20 can be perfect all the way images!
DVR GS20 uses a top us WDR wide-area wide dynamic image processing technology and extreme wide dynamic processing chip. WDR wide dynamic unique night shrinkage and good technology to the light, make the night brighter, can eliminate a light, bright light, the reflective on vehicle traveling data recorder, and video produced by the fuzzy phenomenon such as glare, no matter to the sun during the day backlight, backlight, tunnel or at night lights glare live glare vehicle license plate and so on all sorts of bad environment, DVR GS20 can clear to capture the surrounding environment, image and license plate number, license plate is not reflective, still can clearly see the characters in the backlighting.
Using the world's best German imports six-story transparent glass lens, leading industrial pervious to light lens module, A full range of using grade A glass material, implements the 170 degree big wide Angle, ensure quality more thoroughly, details is more clear.


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I have lived in Alabama: Round Two 2 years and 3 months. Lots has happened to me in that time. In fact, my life, since 2005, has changed quite radically. I've gone from owning a home and sort of being in control of everything - gardening and dinner parties, volunteering with community projects, and riding my horse ... oh Hell, let's just call it Junior League - to sort of being on not really a freefall, but definitely a freeway. It's difficult to describe.
What I recognize is that we should not expect to replace our history in our present, but realize its value as an archive which allows us to reference a safe place or a fond memory, reminding us there is hope and peace to be had. I always recognize the filters the mind places on our memory - seldom does the insignificant stick or make a lasting impression on the long-term. At least it doesn't for me. If it did, I'd rather just shoot myself now and get it over with.
There are times when my life in Arkansas seems like it was a dream. 10 years I lived there and sometimes I barely remember it. I know it's because I'm in this sort of vortex where I try to cram a million things into a day. Not very healthy, of course, but it's my reality. I'm not unraveling, I'm just constantly being challenged to define what's important to me. But when I reflect on Arkansas, all I remember are good things. Happy things. It's almost like watching a movie.
Yesterday I was overwhelmed with a sense of driving down Interstate 30 toward Dallas, somewhere in North Texas (probably around Sulphur Springs). It was Spring and everything was chartreuse, and grackles were flying all around. We were en route to a horse show in Weatherford and I was with my friend Kim. Maddie was not even a year old then but she was in the back seat being her unique little Jack Russell self (read: chewing things up). I don't know why I was flooded with the memory but it made me happy. It reminded me of a horse who is no longer with me, a friend who I don't speak with regularly but who I cared a great deal for, and a moment in my life that was, apparently, significant in its simplicity.
Tuesday, September 09, 2008
Break Down Here
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Everybody leads with what the Washington Post describes as the "largest U.S. ground assault of the war" in Afghanistan. The papers note that the Pentagon hasn't released many details about the battle. But the gist, which everybody picks up, is that rather than a direct assault, which seemed to go so poorly on Saturday, allied forces (including contingents from Australia, Canada, Denmark, France, Germany and Norway) have decided to simply surround the al-Qaida guerrillas and let warplanes bomb them.
As everybody reports, unlike most previous operations in Afghanistan, conventional U.S. ground troops have been used directly in combat. According to both the New York Times and WP, 34 American soldiers have been wounded, none with life-threatening injuries. (The Wall Street Journal puts that number at only 14, but Today's Papers bets that that's a mistake, since the Post reported that a Pentagon official said that of the 34 injured, "14 had already returned to the battlefield.") Meanwhile USA Today reports that an Afghan commander says he saw another American soldier killed, in addition to the one that's already been reported. The paper says the Pentagon "couldn't confirm" the death. Everybody also reports that a number of U.S. helicopters were hit by enemy gunfire, though none were shot down.
The papers note that the Pentagon disputed claims that there are 5,000 al-Qaida and Taliban troops in the battle. Instead, the military said there are hundreds of them.
A Los Angeles Times news analysis gives the operation its nod of approval, saying the Pentagon has addressed the problems that plagued last year's campaign in Tora Bora, namely that so many al-Qaida fighters escaped: "This time, defense officials and military analysts say, the Pentagon is doing it differently." That may be, but as the Post emphasizes, this operation's initial attack, at least, hasn't gone too smoothly. According to the paper, U.S.-led forces were on their way to attack a group of al-Qaida remnants, when the al-Qaida forces opened up with a withering mortar and machine gun attack. According to the Post, "The al-Qaida shelling kept the U.S.-led forces off balance and [the allied troops] eventually retreated about six miles."
Everybody notes comments, from what appears to be the same "senior defense official," that the Pentagon had been preparing this assault for weeks. The Post adds that the planning for it "went all the way up to Secretary of Defense Rumsfeld." The NYT adds that it went all the way up to the president.
The WP quotes a number of Afghan soldiers and commanders who were incredulous at what they saw as the sloppiness of the U.S. plan. "The American command was really bad," said one wounded Afghan fighter. Added another, "They went ahead without making trenches, without reinforcing their positions. And then they were cut off. They retreated really badly."
The NYT interviews some residents in the area who say that no top-ranking al-Qaida or Taliban figures have been, or are in, the neighborhood.
Trying to explain why so few details are known about the operation, the NYT says, "Faced with the intensity of the bombing, Western reporters were unable to move closer to the center of the fighting than Zormat, a district town that appears to have acted as a rallying point for Taliban and al-Qaida fugitives." Bombs, though, may not be the only things stopping reporters from getting to the scene. Yesterday's NYT reported that the Pentagon "barred" Western reporters from reaching the area. Today's Times doesn't mention if that policy has changed.
The NYT gives a good sense of what kind of environment this battle is taking place in: on a mountain range with nearly 12,000-foot peaks.
Yesterday, the papers quoted a Pentagon spokesperson suggesting that some U.S. troops were in trouble: "As of right now we've got some of our people who need help." What happened to them?
The LAT mentions that an earthquake measuring 7.2 on the Richter scale struck Afghanistan yesterday. It's not yet known how many people died.
Everybody fronts violence in Israel. Yesterday, a Palestinian sniper opened fire on an Israeli checkpoint in the West Bank, killing 10 people, seven of them soldiers. Twenty-one Israelis have been killed in the past 24 hours.
The papers say that responsibility for the attack was claimed by the al-Aqsa Martyrs Brigades, which the LAT describes as, "a militia linked to Arafat's Fatah movement." Once again (and for the last time), Today's Papers suggests that somebody do an article describing what's known about those connections.
The papers report that Israel—which declared that it would put "continuous military pressure" on Arafat—retaliated with airstrikes against Palestinian Authority targets, killing four Palestinian police officers. Israeli troops also entered a refugee camp in the Gaza Strip and in subsequent clashes killed three Palestinians, including one gunman and two civilians.
The Post says that of the nine people killed in Saturday's suicide bombing in an Orthodox neighborhood, seven were from the same family.
Everybody notes that the much-discussed Saudi peace plan might already be dead. An aide to Israeli Prime Minister Ariel Sharon dismissed it out of hand, while Libya and Syria dissed it as well.
Following on reports from NYT columnist Nicholas Kristof and others, the WP stuffs a news dispatch from the Philippines questioning the U.S.'s choice of targets in that country: "Concentrating on the small group of Abu Sayyaf rebels, the U.S. effort sidesteps bigger and potentially more dangerous groups with stronger connections to Bin Laden's al-Qaida terrorist network." (By the way, this WP story was bybusy guy Doug Struck, who just a few weeks ago was in eastern Afghanistan—having a gun pointed at him by U.S. commandos.)
The NYT does a front-page piece reporting, "With the Senate likely to approve landmark restrictions on political fund-raising, Republicans and Democrats are mounting an aggressive, last-ditch drive to collect unrestricted checks from wealthy donors before such donations are banned." According to last week's WP, "As legislation to overhaul campaign finance laws nears final passage, leaders of both parties have launched all-out, last-chance drives to raise millions of dollars in 'soft money' donations, which may become illegal by year's end."


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Update on my fundraiser! If you haven't seen my video click on this link: http://bit.ly/2BU2ATi
Almost $10,000 Raised
A huge thank you to everyone for your thoughtfulness and generosity during this holiday season!
Because of you, we have raised nearly $10,000 to support Dr. Swanson's research. We are hoping to make our goal of $25,000 by the end of the year. Donations are 100% tax deductible, and the gifts go directly to Dr. Swanson's research to discover how Katie's genetic alteration causes nervous systems to develop in slightly different patterns. He will tackle this difficult challenge in part supported by your generous donations.
This research has the potential to shed light on this rare gene mutation not only for Katie, but for others as well. Thank you again!
Happy Holidays,
The Murphys


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Vidyo, Inc. today announced the first product resulting from its on-going relationship with Google, a software-based solution that enables H.323/SIP video conferencing and IP PBX systems to connect users into Google+ Hangout Sessions. The new product will extend usability by allowing connectivity with existing business voice and video solutions from Cisco, Polycom, Lifesize, Avaya and Vidyo. VidyoH2O™ for Google+ Hangouts will be offered on a subscription basis both on-prem and as a cloud-hosted product.
"In August of 2013, we announced that Vidyo is developing a Scalable Video Coding (SVC) extension for VP9 and WebRTC and will be leveraging this joint development effort to enhance the Google+ Hangouts experience in an enterprise setting," said Ofer Shapiro, co-founder and CEO of Vidyo. "VidyoH2O for Google+ Hangouts is the first of an expected series of innovative solutions resulting from this WebRTC collaboration with Google. This is another example of how Vidyo is driving the convergence of consumer and enterprise solutions."
Vidyo's patented VidyoRouter™ leverages Scalable Video Coding (SVC) which is recognized by most industry players as the way to deliver a great video conferencing experience over the Internet. The VidyoRouter enables better error resilience and allows an optimized experience for multi-user video calls. WebRTC provides the ability to participate in video calls without a separate client or plug-in installation. WebRTC with scalability will give Web developers who are using VidyoRouter in their implementation access to even better video quality coupled with the no-install advantage. Chrome is expected to be the first browser to support the scalable version of WebRTC and, together, Vidyo and Google will promote this version with relevant standards bodies.
"Google+ Hangouts creates a new channel and market opportunity for Vidyo, and enabling interoperability with existing video conferencing and phone systems is great news for enterprise users, as well," said Roopam Jain, Principal Analyst at Frost & Sullivan. "It will be exciting to see what further developments stem from this WebRTC relationship between Google and Vidyo. Vidyo continues to be at the forefront of driving innovation in the video communications market."
Pricing and Availability
VidyoH2O for Google+ Hangouts is scheduled for general availability on March 31, 2014, on a subscription basis starting at $99/port/month for on-premise deployment, or as a cloud-hosted product for $149/port/month.
To receive additional information regarding VidyoH2O for Google+ Hangouts, please click here or send an email to firstname.lastname@example.com.
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Probolomyrmex guineensis , Taylor, R. W., 1965
Taylor, R. W., 1965, A monographic revision of the rare tropicopolitan ant genus Probolomyrmex Mayr (Hymenoptera: Formicidae)., Transactions of the Royal Entomological Society of London 117, pp. 345-365: 353-355
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|Probolomyrmex guineensis
sp. n.
Probolomyrmex guineensis HNS sp. n. (figs. 11, 12)
A series of Probolomyrmex HNS from Guinea, originally housed in the Santschi collection but subsequently distributed, has been mentioned several times in the literature under the name filiformis Mayr HNS , following Santschi (1914). I have retrieved three specimens of the original seven in this series and find them to be representative of a new species, here described.
Holotype worker
HL, 0.61 mm.; HW, 0.41 mm.; SL, 0.38 mm.; CI, 67; SI, 93; WL, 800 mm.; PW, 0.30 mm.; dorsal petiole width, 017 mm.; petiolar node index, 57; petiole height, 0.31 mm.; petiolar node length, 0 - 25 mm.; lateral petiolar index, 84. General features are shown in the figures. Close to P. filiformis HNS , but differing from it in the following characters: (1) Smaller size, with relatively broad head, short scapes, and narrow, shorter petiolar node - as indicated in the above dimensions. (2) Punctural element of sculpturation more distinct (shagreening developed on all body and appendage surfaces, as in filiformis HNS ). Head capsule with moderately distinct superficial punctures, about 0 005 mm. in diameter, separated by distances about equal to their average diameter; those on sides and postgenal areas most distinct. Puncturation of entire pronotum and remaining mesosomal dorsum similar to frons; punctures of mes- and metepisterna larger and more distinct. Petiole and first 2 segments of gaster with larger shallow punctures, about 0.01 mm. in diameter, separated by distances averaging about half this value. (3) Concavity of declivitous propodeal face, viewed from above, about onequarter as deep as distance separating dorsal points of propodeal lamellae. (4) Subpetiolar process lacking an acute posteroventral tooth. When viewed from above, no trace of a median emargination of the posterior flange of the node.
P. guineensis HNS resembles filiformis HNS in all other respects, apart from slightly paler coloration. The three apical maxillary and the terminal labial palpal segments are proportioned as in P. angusticeps HNS .
Paratype workers
Two paratype workers agree with the holotype in all essential characters, including details of the measurements and indices.
Holotype [[ worker ]] and 2 [[ worker ]] paratypes, Guinea: Nigorie, Kakoulima (Silvestri). The holotype is deposited in the Naturhistorisches Museum, Basel, paratypes in the British Museum (Nat. Hist.) and the Museum d'Histoire Naturelle, Geneva. There are differences in the original labels on these specimens. That of the holotype reads: Nigorie, Kakoulima (Silvestri); the Geneva Museum specimen has: Kakoulima 12 Ag. 1912; and the British Museum one has: French Guinea - d. F. Santschi - G. A. (presumably G. Arnold) - 1914.
No known copyright restrictions apply. See Agosti, D., Egloff, W., 2009. Taxonomic information exchange and copyright: the Plazi approach. BMC Research Notes 2009, 2:53 for further explanation.


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I've not read the original Dark Souls, but I was intrigued by the idea of Dark Souls: Winters Spite so when the copy became available, I grabbed it. I have to say, I'm glad I did. For the opening alone, I love this story line.
The Heart.
It is a fragile thing.
But surely naught within this world holds greater power.
Those who nurture its gifts know only satisfaction; their lives lit gloriously aflame. But those of wicked intention, who'd foster neglect therein, shall feel its true frigidity. (Dark Souls Winters Spite #1)
The first page of this comic tells the tale of a lady and her kingdom, and the dark winter that has been cursed upon her. It is worth the read alone for the beautiful language. The rest of the comic follows as the introduction to Andred of Ithvale, a warrior on a mission. His mission? To retrieve a precious sword that has been stolen from him. The problem with this is, that on the path of his mission he encounters a land ensconced in blizzard and he ends up captured; left chained to a wall in a dungeon, until the time that he is put to battle to entertain his captors. He wants to escape, he plans and rests and bides his time, but will it all be for naught?
As he continues to best the men and beasts that are put to him by the captors he does not know, the fights get harder, his opponents bigger and stronger. Will Andred be able to fight his way free? What does he have to do with the Lady of Almeria, the land that he is enslaved in? This first issue does not answer any questions, instead it lays the groundwork for what I hope ends up being a truly epic fantasy story.
I'm very much looking forward to see what happens next for our hero, but first, he must get himself unchained. perhaps that will happen in the next issue due out next month.


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This café fixie hybrid bike exudes the spirit of the 1960's motorcycle era. Its lean & mean raw speed & fast attitude is directly inspired by the aggressive café racer outlook. The stripped-down appearance and shapes mimic the original measurements, angles, and lines of this 60's masterpiece. But don't be mistaken, the café fixie hybrid is more than just a styling exercise. With its functional belt-drive single gear system and an internal rear hub motor with a high capacity battery 400Wh, this bicycle can truly put "the pedal to the metal". The 180mm disc brakes ensure a smooth stop instantly, prefect for urban life. The entire concept of this bicycle is based on reliability, sturdiness, low-maintenance and more important speed and handling. The café fixie hybrid is therefore ideal for young hipsters looking for an urban mobility solution that actually looks & feels cool, smart and unique.
Join us on our social networks for all the latest updates, product/service announcements and more.
Grenzweg 1,
Pfeffingen, Basel-Landschaft, Switzerland.
STUDIO LATA is a creative agency specialized in product design that strives to understand and translate user needs to feasible products of tomorrow.


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Finding useful info about Bankfoot is becoming ever more difficult as the number of sources for Bankfoot, Scotland data on websites increases on a daily basis. Visione offers one of the most comprehensive databases of Bankfoot information available anywhere on the Internet.
People in Bankfoot commute to Perth for a variety of job oppertunities. Bankfoot in Scotland is part of the "Perth and Kinross" local authority and is in the Scottish constituancy of "Ochil and South Perthshire"
The population of Bankfoot is 1136. Visione's aim is to provide you with central resource for Bankfoot - a valuable collection of links and reviews you'll be pleased with.
Visione has collected the best resources together to provide community information for Bankfoot
Whatever information your are searching for about Bankfoot find it here. Local Authority and Commuting from Bankfoot Population statistics forBankfoot area.
What do people think about Bankfoot and what does it look like? Discover the history of villages and towns in Ochil and South Perthshire and where your relatives may have been born, stayed, or died. Many emigrated from Scotland and it important to trace relatives. Places and cummunities evolve and are changing rapidly. It is important to maintain a historical record.
Navigate using the map between different cities, town, village hamlets across Scotland. From the borders and central belt to the Scottish highlands thousnads of settlements are listed. Information database. The Scottish capital of Edinburgh and Scotlands industial heartland of Glasgow have listings. Pictures taken by locals and submitted are displayed. Did your ancenstors live there.
Visione, Bankfoot.
information for Perth and Kinross and Bankfoot
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map for Ochil and South Perthshire and Bankfoot
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Page last updated : Thu Sep 17 20:49:59 2009
Page last updated : Thu Sep 17 20:49:59 2009


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3D printing goes flat out• http://phys.org, by Lesley Parker
"In itself, 3D printing isn't going to be a source of competitive advantage but it will become an industry standard," says Dr Hermens. This means businesses that don't keep up with the technology and the design possibilities it offers, won't survive.
"Will it bring manufacturing back onshore? No, because the technology is available globally," Dr Hermens says. "But it will change the way we compete, and the competitive advantage will be in the design of the [product] models themselves."


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"When you dress up you don't need to worry about meeting people. If you look good, good looking people will flock to you. That's a life lesson. If all your friends are ugly you should probably start wearing more makeup."
Read the full interview on Freedom Spark HERE.
Categories: freedom spark, interview, moi, press, stella rose, stella rose saint clair


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5 Helpful Tips To Make Your Diet Better
Most people desire to improve their diet as a means to better their health or lose weight. Even if improving your diet is a good goal, it is not simple to do and demands a strong commitment. It can be extremely difficult to alter everything at once so it makes perfect sense to alter things slowly over a period of time. Just add in better foods and get rid of the junk food. The following are some ways that you can make your diet healthier.
Eat a balanced diet
Consuming a well-balanced diet is a good idea as eating one thing again and again is not great for your health. Moderateness is the key for many things in life, including food. Be sure to include lots of bodybuilding protein, energy boosting carbohydrates, and adequate amounts of good fats in your diet. And dont forget to eat some fiber to keep your digestive system working right.
Avoid eating too much during each meal.ernährungsplan zum abnehmen
Try keeping your meal portions small. Large numbers of us overeat merely because the food is easy to get. When we sit at the dinner table to eat, were feeling hungry so we serve ourselves more than we can reasonably consume in one sitting. When you consume too much food, your stomach gets bigger and starts to need more food to feel full, which in turn can cause you to gain weight. You can shrink your tummy by slowly cuttong down how much food you take in at a time so that your stomach comes to accept that as normal.abnehmtipps
Consume plenty of fruits and veggieseiweiß diätwie kann ich schnell abnehmen, wie kann man schnell abnehmen
You should try and get fruit and vegetables in your diet because theyre very good for you. They are loaded with the needed vitamins and minerals. Include at least five servings of fruits and vegetables in your diet everyday. That means you consume anything like apples, bananas, carrots, lettuce, broccoli, grapes, etc.eiweiß diät Its not as hard as you might believe.
Take your time eating your repastsabnehmen im schlaf
Eating your repast in a slow manner is very essential since your brain doesnt know youre full until 20 minutes have passed. This is why you find people going back for seconds 10 minutes after they consume a huge amount of food. Ten minutes later they feel really ill at ease. Sit and relax as you consume your food.diät tipps
Try not to eat too much sweets.schnell abnehmen
The sweet taste of sugar is one that most of us truly enjoy. Even though its virtually impossible to totally avoid sugar, you can reduce on how much you eat. Consider consuming fruit or a sugar-free dessert over the usual sugar-laden dessert. Drink diet sodas instead of regular sodas.tipps zum abnehmen
Just observing these five tips can make a great difference in your health and how heavy you are. These suggestions are so simple you should have trouble executing them.abnehmtipps


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Since the dawn of Pinterest, you've had your eye on one of those gorgeous candy-colored KitchenAid mixers. (Ice blue, please.) Alas, shelling out $440 for an appliance is hard to justify unless you're a professional baker.
That's where the new KitchenAid Artisan Mini comes in. It's a cheaper—but just as powerful—version of the OG. The price? Only $329 (you basically save $100). It's still an investment, but a much more reasonable one.
Really, the main difference between the mini and the classic is the size (it's just 3.5 quarts compared with five), but if it means not giving up precious counter space, we're sold. Plus, it can still fit enough dough to make five dozen cookies in a single batch. It's also 25 percent lighter and comes in 11 cool colors like hot sauce and guava glaze.
Cue the Instagrams.


text: Expressionist Slideshow 2 minutes 19 seconds Over a period of three days in December 1986 and January 1987, I created two 3' x 25' scrolls, one after the other. Reproductions of the scrolls' various segments are available upon request. The original scrolls are for sale; please call or email to inquire.


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Community Initiatives
How are communities responding?
Many local governments and their communities are proactive in addressing graffiti and other offending behaviours, and have their own graffiti management strategies in place to target specific graffiti problems within their jurisdiction. Use the links below to learn about some local graffiti management strategies and initiatives in place within our State. Please note, the graffiti initiatives highlighted do not necessarily reflect the views of WA Police or State Government.
The City of Gosnells has a zero tolerance to graffiti and has an anti graffiti team that removes graffiti as soon as possible after notification. Racist and offensive graffiti is removed immediately if we are allowed access to it, after Police enquiries have been made. The anti graffiti team removes graffiti from City assets, private homes and businesses under certain conditions and works closely with the Police to ensure a coordinated approach to identifying and prosecuting graffiti vandals. The City is proactive in its approach to graffiti and provides various programs to educate and decrease graffiti in the community.
The Safe City Education Project for Schools (SEPS) deals with crime prevention on a basic level and helps students understand the importance of reporting graffiti and vandalism, how to encourage parents to join Neighbourhood Watch and how to become more responsible members of the community. The program is free to all schools in the City and is presented by representatives from WA Police and Safe City.
A number of responsible businesses have joined the City's Business Accord to reduce graffiti in our community. The accord aims to restrict access to items that are used illegally and are contributing to the amount of graffiti in the City.
The Adopt a Bus Shelter program is a community based program the City is involved in to tackle graffiti. This program relies on the involvement of volunteers who are passionate about reducing the visual effects of graffiti vandalism in their community and lessen the reward for the graffiti vandals.
The City of Rockingham have a series of graffiti prevention and reduction strategies. The Community Graffiti Paint Out program encourages energetic and enthusiastic members of the community to remove graffiti by providing volunteers with paint, a paint brush, a scraper, a mask and disposable gloves to paint over graffiti markings on bus shelters, bus stops and underpass walls and other approved structures. This project has proven to be highly effective with a marked reduction of graffiti vandalism on maintained structures.
The Adopt A Bus Shelter program involves schools and community groups working with a local artist to revitalize and protect bus shelters in 'hot spot' areas. Students address the issues surrounding graffiti as well as contributing to choosing effective mediums which are harder to vandalize whilst working on a community theme. Artworks are completed using different processes such as ceramics, metal inserts, textured metal, aerosol art and painting. Recurrence of graffiti vandalism to decorated bus shelters has been greatly reduced. Urban Art Projects also encourage young people to participate in workshops to learn about the widespread effects of graffiti vandalism on the community and the history of hip hop and urban/graffiti art. Courses and employment information are also provided. A renowned urban artist works with participants on theme, design, skills and technique before artworks are spray painted onto a skate park, change room facilities or the like. The projects so far have been highly successful and have received much community praise and support.
Constable Care Child Safety Foundation (Inc)
Constable Care have developed an 'early intervention' graffiti education program titled 'To Tag or not To Tag: It's a Life Choice'. The project strategy is an Interactive Drama Play targeting Primary School Children in years 4-7 (9-12yr olds). Contact: David Gribble on (08) 9272 0000.
Neighbourhood Watch (Western Australia)
Neighbourhood Watch is a series of programs aimed at making individuals aware of crime prevention initiatives and activities by encouraging interaction and a sense of responsibility between neighbours and communities. Contact: Jenny O'Brien on (08) 9222 1513.
Developed electronic mapping of graffiti and hotspots, linked to the Towns 'Intramap' system, along with regular reporting to WA Police. The Town also offers an extensive community assisted graffiti removal service for residents and business and will remove any graffiti reported visible from a public area, within 48 hours or within 24 hours if deemed offensive/ racist.The Town offers 'Vincent graffiti safewipe citizens' packs for town residents and businesses'which has been received very well by residents and business.
The City of Karratha (formerly Shire of Roebourne) received a State Graffiti Fund grant to develop the Roebourne Community Art project. Members of the community had expressed an interest in pursuing projects to beautify Roebourne's public spaces and create a sense of pride amongst young people and community members.
The project aimed to encourage a sense of ownership, pride and respect for the artwork and the Roebourne Community Hall. The murals were painted by artist Marina Baker but were designed with extensive input from local young people, art groups and the broader community. The artist was engaged to facilitate the art project because she has extensive experience in mural art projects and working with Aboriginal communities across Australia.
Click City of Karratha-Cleansweep Graffiti Project for further information.
Do you have a local graffiti management strategy or initiative you want to highlight?
The Goodbye Graffiti website aims to be community orientated by providing relevant information to address graffiti vandalism and facilitating the exchange of such information between communities.
If you have a local graffiti management strategy or initiative that you would like to share with other communities please email WA Police Graffiti Team with the following information:
- name of graffiti strategy / initiative;
- website address (if available);
- brief summary of the strategy / initiative (100 word maximum); and
- contact person (including a telephone number and/or email address).


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Manuscript login
Global reach, higher impact
International Journal of Medical Sciences
Journal of Bone and Joint Infection (JBJI)
Int J Biol Sci 2007; 3(7):402-407. doi:10.7150/ijbs.3.402
Research Paper
DNA damage repair is unaffected by mimicked heterozygous levels of BRCA2 in HT-29 cells
Department of Biology, Adelphi University, Garden City, NY 11530, USA
Functional loss of both alleles of the breast cancer susceptibility gene, BRCA2, facilitates tumorigenesis. However, the direct effects of BRCA2 heterozygosity remain unclear. Here, BRCA2 heterozygosity was mimicked in HT-29 colon cells by reducing levels of BRCA2 through stable RNA interference. No difference in RAD51 subcellular localization and focus formation was observed between control and mimicked heterozygous cell lines. DNA repair ability, as measured by colony survival following mitomycin C treatment and ultraviolet radiation exposure, was also unaffected by reduced levels of BRCA2. Interestingly, the growth rate of the mimicked BRCA2 heterozygous cell line was significantly lower than that of control cells. Increased expression of p53 in the mimicked heterozygous cells was observed, perhaps in response to BRCA2 deficiency. Levels of p27 were also found to be slightly increased in cells with reduced BRCA2, perhaps contributing to the slower growth rate. Overall, these results suggest that tumors are unlikely to arise directly from BRCA2 heterozygous cells without other genetic events such as loss of the wild-type BRCA2 allele and/or loss of p53 function or other cell cycle inhibitors.
Keywords: BRCA2, heterozygosity, RNAi, DNA damage repair
This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Tannenbaum B, Mofunanya T, Schoenfeld AR. DNA damage repair is unaffected by mimicked heterozygous levels of BRCA2 in HT-29 cells. Int J Biol Sci 2007; 3(7):402-407. doi:10.7150/ijbs.3.402. Available from http://www.ijbs.com/v03p0402.htm