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Haxe US-Summit 2019
May 8-10 @ Seattle
The US Haxe Summit is a three day event which will take place in Seattle in May 2019. It is the main Haxe Community Event in the US and a great meeting spot for the people who create Haxe, people who work with it or people who are new to Haxe and want to explore it.
We will have a mix of presentations and workshops about topics ranging from game development with Haxe to things you can get up to on the Web.
Join us to:
- meet the people who create the Haxian tech you are using
- connect with other developers who may know a thing or two about Haxe that you don't
- get a fresh boost of inspiration and motivation.
And all of that even before the conference party has worked its magic.
See you soon!
Are you :
- doing something exciting with Haxe that you would love to tell us about
- solving a pesky problem (workflows and tooling, anyone?);
- looking to pass on some Haxian wisdom?
Then we would love to hear from you!
We are interested in quick showcases, more thorough presentations and full workshops.
Not sure if you should get up on that stage? Apply anyway! We will help you figure it out.Speak Up!
The Haxe Summit is like a yearly dose of fresh energy for the Haxe community and the makers of Haxe. Help us put on a good show and grow the community. Who knows, you might even meet your future Haxe developer while you are enjoying the Summit with us!
Sponsor the Event
Are you interested in sponsoring this event? Awesome, we would love to hear from you.sponsor the event
The full ticket price will be 450 USD so take advantage of our Early bird pricing now! Early bird pricing will be until 28th February.
The conference will take place at Seattle Downtown, more details coming soon
Not yet available
… and the occasional evening party of course!


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All rights reserved to Kaysie Bekkela, if you see something you like please contact the writer via her contact page.
I found this piece of gold hidden in my files...
A has a pop tart.
B: Hey
A: I got a poptart
B: I can see that
A: good
Love Texts to My Lover
Read 10:08 PM THURSDAY
Hey. So I was at a party tonight. And I felt you in me. So I looked at my friend and was like, "I'm a little intoxicated." She goes, "Yes you are. I like you intoxicated." And I was like, "Me to."
I'm drinking now. I'm a little drink.
I'm debating if I should finish this water or finish that bottle of wine I started last week.
My mom thinks I spend too much time with you. But I'm like, "that's not even true." She thinks I'm an alcoholic. But I don't even have fun!
I have fun when I'm with you though. You just- I feel like wooh! Around you. I just tell people I love them. Yo, without you I would have never kissed that one guy. I feel like I don't tell people how I feel often or let go often but you like encourage me.
Read 11:01 PM THURDAY
The Queen and The Jester
This one of my favorite pieces I've ever written. It's a little bit older but it's still a good time.
We are at the Castle. The QUEEN sits in her throne, she is a drag queen, she is twiddling her hair. Her JESTER sits on the floor hitting the bells on his hat.
QUEEN: Jester, would you be so kind as to entertain me?
JESTER: Shall I do a nice jig around you?
QUEEN: A horizontal jig?
JESTER: No ma'am An Irish one.
QUEEN: Perhaps. Let me see it.
JESTER begins his jig.
JESTER: How's this your majesty?
QUEEN: Your hat is poking me.
JESTER: My bad your majesty.
QUEEN: No, no. It's fine. I don't mind a poke or two.
JESTER: Yes your majesty.
JESTER dances close-ish to QUEEN so that his bells occasionally hit her.
QUEEN: You know I used to be called quite the lobster kettle in my day.
JESTER: Your majesty?
QUEEN: Not familiar with the phrase are you?
JESTER: No, your majesty. Has it anything to do with eating the sea creature?
QUEEN: Yes, in a way.
I hate to ask this of you, do you mind…tipping the velvet?
JESTER nods, walks over to the curtains and rips them down.
That time I tried my hand at Criticism: The Goodman's Carlyle
The obvious hero of The Fresh Prince of Bel-Air is Will Smith. He's cool. He's bad. He's trying to make his way in the world. It's is a classic underdog story. Young boy from the bad streets of West Philadelphia leaves his neighborhood playground for the great wide Bel-Air. A truly classic American tale of assimilation. Boring! No one wants to hear another Will story. What the audience really wants, what they really need is the untold story of Carlton Banks! The story of a boy who doesn't always fit in. A boy who wears khaki pants! A boy born into riches! A true account of a black republican! A story never before told! Until now…
Here's a scene I wrote for The Comedy Show featuring one of my favorite characters, Aunt Margie!
In a class room characters get into place as class starts.
Happy first day of sex ed! Name's Margie but you can call me Aunt Margie, everyone does.
Yo. You gonna show us how condoms work?
Oh honey if you don't already know you're doing it wrong if you know what I'm saying.
She goes for a high five. Doesn't get it.
Slap it!
Still no high five.
Kid 2:
My mom says absentness is the best method of birth control and that it should be illegal to teach sex ed in school. And that you're a devil woman.
Oh honey your mom isn't the most innocent cow on the farm . if you know what I'm saying!!!
I hear that Margie!
Kid 3 goes for a high five. Margie takes it.
He knows what I'm talking about.Alright you frisky freakydeaks let's get rolling!...That's what he said am I right?
Goes to get high five from Kid 1 or 2 doesn't get it. Goes for kid 3, get high five. It's an under the leg, low five. Kid 2 raises hand.
All rights reserved to Kaysie Bekkela , if you see something you like please contact the writer via her contact page.

subset: commoncrawl


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Union Power, Kyriarchy and the Scab
On the Use and Misuse of the Term "Scab"
November 30th: The women fight back
Earlier this week, the Guardian asked the women of twitter what pissed them off most about the Con-Dem government. It was a testimony to women's ingenuity that so many were able to fit so much into 140 characters. Among the many, many answers given were childcare cuts, attacks on employment rights, legal aid cuts, scrapping …


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Breaking News Emails
Erdogan Declares State of Emergency in TurkeyJuly 20, 201600:40
NATO member Turkey on Wednesday deepened a crackdown on suspected followers of a U.S.-based cleric it blames for a failed coup, dismissing nearly 1,700 military personnel and shutting 131 media outlets.
So far, tens of thousands of people — including police, judges and teachers — have been suspended or placed under investigation since the failed putsch. Turkey alleges it was staged by a faction within the military loyal to the Muslim cleric Fethullah Gulen.
Gulen, who lives in self-imposed exile in Pennsylvania but whose movement has a wide following in Turkey where it runs a large network of schools, has denied any involvement in the coup.
Western governments and human rights groups, while condemning the abortive coup in which at least 246 people were killed and more than 2,000 injured, have expressed concern over the extent of the crackdown. Some suggest President Recep Tayyip Erdogan may be using it to stifle dissent and tighten his grip on power.
Erdogan says the Gulen movement threatened democracy by attempting to build a "parallel state" within the military, media and civil service.
U.S. State Department spokesman John Kirby said Thursday that the department was "deeply concerned" by the reports of a media crackdown.
"The United States supports freedom of expression around the world. And we have concerns when any country makes a move to close down media outlets and restrict this universal value," Kirby said. "We expect Turkish authorities to uphold their assurances that the Turkish government will protect the rule of law and fundamental freedoms."
On Wednesday, the military dishonorably discharged 1,684 of its personnel, a Turkish government official said, citing their role in the failed coup. Of those, 149 were generals and admirals, said the official, who requested anonymity. Data show that would represent roughly 40 percent of all generals and admirals in Turkey's military.
Broadcaster CNN Turk has reported that more than 15,000 people, including around 10,000 soldiers had been detained so far over the coup, citing the interior minister. Of those, more than 8,000 were formally arrested pending trial, it said.
See Turkish Intelligence HQ Strafed by Rebel HelicopterJuly 18, 201600:37
In addition, the government said in its official gazette that three news agencies, 16 television channels, 45 newspapers, 15 magazines and 29 publishers have been ordered shut down.
These moves, which follow the closure of other media outlets with suspected Gulenist ties as well as the detention of journalists will further stoke concerns among rights groups and Western governments about the scale of Erdogan's post-coup purges.
The United States said on Wednesday it understood Turkey's need to hold perpetrators of the attempted coup to account, but said the detention of more journalists was part of a "troubling trend."
Turkey ordered another 47 journalists detained on Wednesday, singling out columnists and other staff of the now defunct Zaman newspaper, the government official said. Authorities in March shut down Zaman, widely seen as the Gulen movement's flagship media organization.
The media reported on Monday that arrest warrants had been issued for 42 other journalists, 16 of whom have so far been taken into custody.
Erdogan's ruling Islamist-rooted AK Party and opposition parties, usually bitterly divided, have demonstrated a rare spirit of unity since the abortive coup and are seeking consensus on constitutional amendments partly aimed at "cleansing" the state apparatus of Gulenist supporters.
Also on Wednesday a government official said Turkish special forces were still hunting in the hills around the Mediterranean resort of Marmaris for a group of 11 commandos who are believed to have tried to capture or kill Erdogan on the night of the coup, when he was on holiday in the area.
Erdogan, a popular but polarizing figure who has dominated Turkish politics for more than a decade, will chair an annual meeting of the Supreme Military Council (YAS) on Thursday after vowing to restructure the armed forces following the coup.
The General Staff said 35 planes, including 24 fighter jets, 37 helicopters, 74 tanks and three ships had been used by the coup plotters, NTV reported. It put the number of soldiers from the Gulenist network involved in the attempted putsch at 8,651, or about 1.5 percent of the armed forces.
Erdogan has also signaled the country might restore the death penalty in the wake of the failed coup, citing strong public support for such a move. The European Union has made clear this would scupper Turkey's decades-old bid to join the bloc.


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Trust Bloomberg Tax for the international news and analysis to navigate the complex tax treaty networks and global business regulations.
Andrew Gilder and Geoff Stiles ENSafrica
Andrew Gilder is Climate Change and Carbon Markets Practice Area Lead in the Environmental Department of ENSafrica and Geoff Stiles is an independent consultant based in Ottawa, Canada
The Canadian province of British Columbia and the Republic of South Africa have developed carbon tax regimes in response to very different political and economic forces: both regimes are considered here.
Canada's province of British Columbia ("BC") and the Republic of South Africa ("RSA") have developed carbon tax regimes in response to very different political and economic forces.
The BC regime is characterized by a simplified tax with a range of compensatory mechanisms, designed to make the tax "revenue-neutral." The BC government has applied the tax across all economic sectors, collecting tax primarily at the wholesale or distribution level; while the RSA regime concentrates on the industrial-commercial sectors, imposing taxation on emissions from a specified list of activities and has developed a complex set of allowances to mitigate the burden of carbon taxation in the first phase of implementation—the purpose of the allowances being to achieve a soft landing of the tax for industrial sectors).
In this article, we have provided a brief comparative description of these two regimes and the approach used by the relevant governments, and we have suggested some important lessons for the development of carbon taxation regimes in other countries.
BC was the first jurisdiction in the world to implement a carbon tax, in 2007. From the outset, BC's tax was meant to be "revenue-neutral", in that individuals and entities affected by the tax would be compensated through reductions in other kinds of taxes, e.g. income and sales tax, or by compensatory grants. The price charged per tonne of carbon dioxide equivalent (tCO2e) was set to increase, from an initial rate of C$10 to C$30 in 2012. Critically, there has been no increase since 2012.
The tax currently produces revenues of upwards of C$1 billion per year. 1
The most significant characteristic of the BC carbon tax is that it is extracted at the wholesale point, i.e. it is levied against distributors of fossil fuels, not end-users (the exception to this is natural gas, which is taxed at the retail level). However, for purposes of making the tax as transparent as possible, government maintains an updated list of the actual cost of the tax as a fraction of the per-liter cost to the consumer.
Of equal importance, government is responsible for tracking the revenue neutrality of the tax. This is done through a relatively simple exercise: the BC government estimates each year its expected carbon tax revenues for the next three years, and enacts tax cuts or other measures which should in principle reduce the tax burden on individuals and businesses by an equivalent amount.
In practice, BC's tax cuts have more than canceled out the revenues collected from the carbon tax, making it slightly "revenue negative" for the government. 2
According to one expert:
… BC's fuel use is down a whopping 16.1%. Its economic growth has kept pace with the rest of Canada. And its personal and corporate income tax rates are now among the lowest in Canada. In short, the numbers indicate that BC's carbon tax shift has been a remarkable success, environmentally and economically. 3
Although lower income tax rates do not in themselves indicate success, there is no doubt that the potentially adverse impacts of the carbon tax have been mitigated by good government policy, and that consumers have reacted to the tax by reducing their use of fossil fuels. Whether this shift is sufficient to offset the introduction of other emissions sources, e.g. large-scale Liquefied Natural Gas ("LNG") developments, is a subject of much debate in the province.
The South African carbon tax, due to be enacted either by mid-2017 or January 2018 at a rate of South African Rand 120/tCO2e, 4 is the result of more than 10 years of sometimes fractious debate and public consultation. In response to the debate, government has developed the complex set of allowances, mentioned above, including:
The potential net effect of tax-free exemptions is to reduce tax liability to between 60–95 percent of total emissions, i.e. the carbon tax will be imposed on only 5–40 percent of actual emissions during the first phase. Although this may seem inadequate, given the country's Paris pledge that emissions can be peaked by 2025 before plateauing for a decade and then declining in absolute terms from 2035, 5 South Africa has other means of reducing emissions including the above-noted carbon budgeting system and its well-regarded auction system for procuring renewable energy projects, 6 as well as its overall commitments to decarbonize electricity production.
The regime also proposes that revenues from the tax will be spent on a range of sustainable interventions, e.g. providing tax relief for rooftop solar power, a reduction in the fossil fuel electricity levy or providing support for free basic electricity.
The only significant similarity between the two regimes is the use of a single rate (Rand or C$/tonne) for all target groups, subject to change over time. Beyond that, the two systems are quite divergent. However, it should be noted that the tax rate in the SA regime is only a fraction of that in the BC regime: 120 Rand/t CO2e (US$8.50, C$11), before allowances are factored in; after allowances, the effective rate will vary from 6 Rand to 48 Rand/tCO2e (US$0.42 to US$3.49, C$4.50).
The most distinctive feature of the BC regime is its relative simplicity. The tax is direct and uniform across sectors and classes, and is collected at the wholesale level for all fossil fuels, with the exception of natural gas. 7 The impacts differ according to the type of user and whether or not they qualify for tax deductions, tax credits, or targeted subsidies.
The SA regime is far more complex, making it difficult to predict its probable impact. While it is intended in principle to be revenue-neutral, in practice it will be far more costly for emissions-intensive sectors, although during the initial phase this will be mitigated through the use of allowances.
A further difference is the SA regime's focus on commercial-industrial users, whereas the BC regime covers all classes of user. Because of strong negative feedback from business, the SA government has been forced to create its complex system of allowances primarily to avoid placing SA business at a disadvantage during a period of economic uncertainty. This also means that the SA regime has little direct impact on emissions in the transportation sector, a significant omission in that in South Africa, as in Canada, transportation is a major emissions source.
Another important difference between the two systems is the use of offsets in the SA regime. While the BC regime was originally to evolve towards a cap-and-trade system in which offsets were permitted, or to permit offsets to satisfy a portion of tax liability, they have moved away from this option and are considering offsets only for the LNG mitigation and "carbon-neutral public sector" programs. 8
By contrast, SA has developed a detailed offsets program, spelled out in the June 2016 document, Draft Regulations on Carbon offsets. 9 It is expected that carbon offsets will reduce tax liability by between 5–10 percent and that demand for offsets created by the tax has the potential to catalyze the local carbon market by sending firm supply, demand and price signals for locally-generated offsets.
Andrew Gilder is Climate Change and Carbon Markets Practice Area Lead in the Environmental Department of ENSafrica (Africa's largest law firm) and Geoff Stiles is an independent consultant based in Ottawa, Canada who regularly blogs on climate change and has over 40 years' experience in the renewable energy and energy efficiency fields.They may be contacted at: firstname.lastname@example.com; firstname.lastname@example.com
1 https://en.wikipedia.org/wiki/British_Columbia_carbon_tax.
2 https://cleanenergycanada.org/wp-content/uploads/2014/12/Carbon-Tax-Fact-Sheet.pdf.
3 http://business.financialpost.com/fp-comment/b-c-s-carbon-tax-shift-works.
4 South African Rand, approximately 10.00 Rand to C$1.00.
5 http://www4.unfccc.int/submissions/INDC/Published%20Documents/South%20Africa/1/South%20Africa.pdf.
6 http://www.ipprenewables.co.za.
7 http://www.fin.gov.bc.ca/tbs/tp/climate/A4.htm.
8 http://www2.gov.bc.ca/gov/content/environment/climate-change/stakeholder-support/developing-emission-offset-projects.
9 www.treasury.gov.za.
Copyright © 2017 The Bureau of National Affairs, Inc. All Rights Reserved.
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It's actually pretty ironic that I have a sex blog. I don't actually have much sex. I guess that's my inspiration. I obsess over sex because I want what I don't have. That is true. If I am having a conversation with a man, my boss, my neighbor, my kid's friend's father I try to picture how they would be in bed.I think I could pretty much have good sex with anybody at this stage of the game. Today I was at work and a guy who works down the hall came in to chat. It's Friday so everything is pretty casual as far as dress and attitude. So this guy was going on and on about his ex-wife and how he googles her but how he is not a stalker and all I can think about is how I would fuck this guy.
He's pretty geeky so it would be especially fun for me I think. Something tells me nerdy guys are especially "giving" in bed. I'd LOVE to find out.
There is a part of me that loves to shock people. I love to make people laugh and I love to turn men on. It's an ego thing with me, I think.
At any rate I wonder if I am the only person that does this. I wonder if men look at me and wonder how I am in bed. I think my appearance is deceiving. I think most men would write me off as a chick that does the missionary position and that's it.
Well, we all know that couldn't be farther from the truth.


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Well, it wasn't until I just sat down to make my bucket-list for 2017 that I realized I did not make one for 2016. It is probably a good thing though because if I don't make lists, then I can't be disappointed when I don't check everything off! Ha
That being said, 2016 still shaped up well for me and I was able to cross off many little things as well as two MAJOR bucket-list items. Like, MAJOR ones!!! The #1 place on my USA list as well as the #1 place on my international list. I'd say thats a pretty successful year! 😀
Fiji and Yellowstone national park . . . Done, and DONE!! YAY! Thank you Jesus!!! 😄
Now for my 2017 list . . . I am going to try to not go overboard on my wish list as we are currently trying to be responsible with our finances and get out of debt. That being said, I'd like to go somewhere, at least one dream place!!! To me, dream places do not nesisarily have to be out of the country, they can be right here in the USA, after-all, there are still TONS of places in my own "backyard" Ive yet to experience.
Ok, without delay, my list of 7 in 2017, in no particular order . . .
- Big family trip over either Easter break or summer vacation – I am 90% sure we have decided on the place(s) as of last night BUT I also thought that 7 places ago, so I am going to keep it a secret until after we actually book it next year. I will give you a hint though, it is not tropical. 🌏
- Host a fitness retreat in a dreamy location – one place that has been on my radar for at least 10 years is Hoh rainforest. I am currently organizing a retreat that will take us to Washington State and Canada early 2017 for some workouts, R&R, hiking, yoga and exploring. Fingers crossed it works out!
- Take Jolee to Great Wolf Lodge. Baby girl has been asking us to take her to Great Wolf Lodge since December 2015. I think 2017 needs to be the year we finally make that happen. She recently started asking about Disneyland too BUT first things first, GWL has to be checked off first.
- Host an overnight fitness retreat close to home, full of adventure and rejuvenation. Looking at Yosemite for this overnight retreat.
- Road trip to a fun place with my WHOLE family. I have 2 sets of uncles/aunts coming from Mexico to visit next year and my local family and I want to find a cabin or beach house to rent somewhere for a couple of nights to do some exploring and sight seeing. Place TBD but we will certainly use AirBNB. If you have never used AirBNB please enjoy $25 on me off of your first stay by signing up using my link ——–> HERE <———– 😄
- Hike at a place I have NEVER hiked before. Near or far, I don't care, it just has to be different.
- Go to at least ONE concert with my love. We really enjoy going to concerts yet for some reason we haven't been to one together in years. We are way overdue so I would definitely like to go to a concert with him some time in 2017.
Looking over this list is kind of overwhelming me. I hope I am able to check off at least 3 of the 7!!! 😁 Do you have a hike you can recommend for my #6 or a concert for #7? Do share!!! 😄 Want to guess our family trip(#1) location? I'd love to hear your guesses!
Will you share your 7 for 2017 with me??? I would LOVE to hear them! 😀


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Category: Metal Fabrication, Job Shop Manufacturing, Case Studies, Inventory
Sales & Customer Service 1.800.364.5958
Instant Manufacturing Business Visibility and Custom Reporting Got Goetsch's Welding
Founded in 1969 by professional welder James Goetsch, Goetsch's Welding & Machine, Inc. started out making fabricated components for large agricultural construction equipment companies such as Case and Caterpillar. Since then, Goetsch's Welding has expanded into heavy construction equipment, paving, medical supply and other general industries. The Wisconsin-based company also builds custom production machinery for the automotive and specialized paper industries.
When Goetsch's began searching for the right ERP system to help support its future growth, management wanted a fully-integrated, single source system that could efficiently manage production while integrating shop floor and back office information. They found this in Global Shop Solutions ERP software.
For General Manager Craig Kowatch the overriding benefit of Global Shop Solutions comes through the integration and visibility of data, which leads to vastly improved process control. Through the robust Inventory software, he can easily drill down to see the status of any job in production.
With easy customization options, Kowatch can review custom reports that indicate which components for a job haven't been completed, allowing him to keep jobs on track. Meanwhile, the person on the shop floor can easily see what has been done, what needs to be done and whether jobs are ready to ship.
"Chasing down this information used to require a lot of legwork. Now we can instantly see what needs to be done instead of scrolling through mountains of paper lists detailing all the different subcomponents. We can get any information we want from Global Shop Solutions."
– Craig Kowatch, General Manager of Goetsch's Welding & Machine
To learn more about Goetsch's Welding, download their case study or any of our other 150 case studies here.


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Investment Management in Financial Services UK
- Select a blog category
Innovation and data privacy: the ICO's technology strategy 2018-21
New technologies and evolving business models have required regulators to review their capabilities and respond to new risks posed. And the UK Information Commissioner's Office (ICO) is no exception. The new General Data Protection Regulation (GDPR) has vested considerable powers to the ICO to regulate and supervise data privacy risks. Increasing concerns about the wholesale use and processing of personal data by firms are reflected in the ICO's recently published Technology Strategy, which outlines its objectives and focus areas through eight technology goals.
The ICO strategy's leitmotif is that technological advances "need not come at the expense of data protection and privacy rights" and that "privacy and innovation are not mutually exclusive". Through the development of its technology strategy, the ICO's overall aim is to remain relevant by ensuring that the monitoring and understanding of technological change, and its impact on information rights, are a core component of its work going forward.
PS18/4: Credit Cards and Persistent Debt
This blog is aimed at credit card providers but has read across to other consumer credit firms such as debt purchasers, credit reference agencies, debt management companies and providers of free debt advice.
Open-Source or Proprietary Software for Credit Risk: It's all about asking the right questions
It is no secret that technology and its impact on companies' business models is shaking up the general market. Technology disruption isn't limited to media, retail, or transport (to name a few industries), but this disruption is widespread, also impacting financial services. The general theme is that technology enabled companies can execute quicker, cheaper and with greater precision.
Pillar 2 Liquidity: Cashflow Mismatch Risk
The PRA recently issued their policy statement on Pillar 2 Liquidity and have finalised the reporting requirements for Cashflow Mismatch Risk (CFMR). This followed the consultation papers released in May 2016 and July 2017. While the policy statement covers CFMR, franchise viability, intraday liquidity and other liquidity risks, this blog focuses on CFMR given the significant implications for firms.
PRA Business Plan 2018/19
The PRA published its Business Plan for 2018/2019 on 9 April 2018. The Business Plan, structured around the PRA's eight core strategic goals, is cross-sectoral, outlining the work the PRA intends to undertake for the upcoming year across both banking and insurance sectors.
FCA's Business Plan 2018/19
This blog provides an overview of the FCA's 2018/19 Business Plan. It discusses the key cross-sector priorities the FCA identifies and compares them to those in the previous year's business plan, noting dropped, changing and new priorities. It also outlines the FCA's sector priorities for 2018/19.
Alongside the business plan, the FCA also published its 2018 Sector Views – the FCA's annual analysis of how each sector is performing – covering retail banking, retail lending, general insurance and protection, pensions and retirement income, retail investments, investment management and wholesale financial markets.
Notably, the UK's withdrawal from the EU is called out as a top priority, over and above any cross-sector or sector priorities. The FCA notes that they will have to dedicate extra resources to this programme of work, and that this will mean reduced activity in other areas as a result.
FCA and PRA business plans: technological innovation remains a priority
Technology and innovation ("FinTech") again featured prominently in this year's Financial Conduct Authority (FCA) business plan. Andrew Bailey, Chief Executive of the FCA, remarked that "technology is supporting competition, transforming markets and changing the way consumers engage with them. […] creating a conveyor belt of risks and opportunity". Given this, and despite the need for the FCA to dedicate a significant proportion of its resources to the UK's withdrawal from the EU, FinTech was confirmed as a key priority for the FCA over the coming year. The two specific FinTech priorities highlighted in the business plan are: Innovation, big data, technology and competition and Data security, resilience and outsourcing.
The Prudential Regulation Authority (PRA)'s emphasis on technological innovation in its business plan is relatively less pronounced. Nevertheless, it too is exploring ways to innovate as a regulator, by continuously monitoring FinTech developments, and supporting the authorisation and supervision of new banks and insurers.
Assessing value for money in investment funds
On 5 April 2018 the FCA published a policy statement, summarised in our recent blog, on its first round measures as part of its asset management market study. Particular interest has been generated by the new rules and prescribed responsibility this contains on assessing value for money. In this blog, we focus on these new rules and consider their implications for firms and senior managers.
AI in financial services - Highlights from the IFGS18 roundtable
Deloitte and UBS[1] hosted a roundtable on Artificial Intelligence (AI) at the recent Innovate Finance Global Summit 2018 (IFGS18). We had representatives from across the FinTech ecosystem covering incumbents, start-ups, scale–ups, consultants and other service providers.
AI is clearly a hot topic and there are a number of challenges and opportunities to explore. We chose four key themes, crowdsourced from experts in the area:
- Navigating the hype
- Bias and transparency
- Collaboration
- Role of the regulator
After a lively discussion, we used a voting system to identify the top messages by theme. The messages that earned the highest number of votes are summarised below.
FCA's asset management market study | Shining a light on value for money
As part of its asset management market study, the FCA has published:
- a policy statement on its measures on fund governance, moving investors to better value share classes, and treatment of dealing profits;
- a consultation paper on proposed measures on investor disclosures; and
- an occasional paper on costs and charges disclosures.
These papers follow the FCA's final report on its asset management market study which was published in June 2017 (see our blog). 1 Below we summarise the key rule changes and assess the implications for firms.


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Site-specific perturbations of alpha-synuclein fibril structure by the Parkinson's disease associated mutations A53T and E46K.
e49750 - ?
PLoS One
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Parkinson's disease (PD) is pathologically characterized by the presence of Lewy bodies (LBs) in dopaminergic neurons of the substantia nigra. These intracellular inclusions are largely composed of misfolded α-synuclein (AS), a neuronal protein that is abundant in the vertebrate brain. Point mutations in AS are associated with rare, early-onset forms of PD, although aggregation of the wild-type (WT) protein is observed in the more common sporadic forms of the disease. Here, we employed multidimensional solid-state NMR experiments to assess A53T and E46K mutant fibrils, in comparison to our recent description of WT AS fibrils. We made de novo chemical shift assignments for the mutants, and used these chemical shifts to empirically determine secondary structures. We observe significant perturbations in secondary structure throughout the fibril core for the E46K fibril, while the A53T fibril exhibits more localized perturbations near the mutation site. Overall, these results demonstrate that the secondary structure of A53T has some small differences from the WT and the secondary structure of E46K has significant differences, which may alter the overall structural arrangement of the fibrils.
AuthorsLemkau, LR; Comellas, G; Lee, SW; Rikardsen, LK; Woods, WS; George, JM; Rienstra, CM
- College Publications [5171]


text: The guy who just nabbed this lovely lady didn't let his catch get away. But he sure ruined my catch. This is an almost shot. Almost great. Almost perfect. Love the colours, love the expressions, the focus, the veil. But I've cropped as far as I can. And the new hubby is still giving me the cold shoulder. Gutted. If I'd known how this would turn out, I'd have shot more frames. Alas, I didn't. This isn't my first 'almost' shot. It won;t be my last. It's one of my most disappointing though.


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I'm a Queen fan. A big Queen fan. Have been since I can remember. Seeing May and Taylor on the big stage is a wonderful thing for me. Nothing else really matters...I went to a number of shows on the two Queen and Paul Rodgers tours and enjoyed them immensely; that though always felt like an odd combination; a blues rock singer, singing songs from a band that were as far away from blues as Brian May is from joining a Boxing Day Hunt. That an American Idol runner up, half the age of May and Taylor, should be any better is laughable of course…yet weirdly…somehow…Lambert is.
Queen music seems to have been sold off as the soundtrack to every advert going (Somebody to Love used to sell sofas anyone?) but at least it keeps Queen music in the here and now. As for Lambert? Well he doesn't have the rock background or rock pedigree and I for one was highly sceptical of what he could bring to Queen. Yet as it turns out he is a front man who not only looks the part but also possesses all the showman qualities needed. Most importantly of all he has one hell of a voice.
We had started queuing at 5.30pm (as we are pretty keen but not stupid). Good enough to get us to the pit barrier. Not good enough to get in the first 200 to get in the actual pit. Luckily fellow Queen geek Mark kept pestering the security guard who said that if we kept near the pit gate we may be allowed in. We didn't move. As the first sounds of One Vision started at 8.25, just as the curtain flew up, just as I was giving up hope, we got the signal and Mark left me for dust as he flew into the pit. Luckily I hung on to his coat tails and somehow we found ourselves three from the front. Marvellous.
The set list tonight contained hit after hit, no real surprises but then who cares. When a band has as many well-known songs as Queen then they shouldn't be ashamed to play to the crowd (as Adam pointed out the trouble with Queen is they just have too many hits). The stage is a throwback to tours gone by and like Queen is way over the top. That though is why I love this band. Everything to the max. Brian May is an iconic guitarist and the writer of many rock classics. Roger Taylor still looks like the rock star that he always was (actually he looks a little too much like Uncle Albert these days....or at least Uncle Albert with attitude). The rest of the musicians on stage include the unofficial 5th member of Queen, Spike Edney, as well as Roger's son Rufus (the spit of his Dad 40 years ago). The line-up is completed by bass player Neil 'not John Deacon' Fairclough and it is obvious that after touring America last year this is a band that are a tight unit.
One Vision is an excellent way to open the show and following that up with Stone Cold Crazy shows their intent right from the off... Lambert is dressed very much like Freddie in his rock star mode and it is clear that that he has all the rock star moves to go with it. Dust, Fat Bottomed Girls (which sees Lambert in his element) follow while Lap of the Gods has the arms swaying. Seven Seas is joyous before Adam drapes himself across a Chaise Lounge for a very funny and camp take on Killer Queen.
I Want To Break Free and Somebody to Love finish off the first half and then it is May's moment. He is front and centre and it is great to see him so happy and relaxed. He sings a light hearted but very much heartfelt Maybe It's Because I'm A Londoner followed by Love of My Life and '39. Roger's up next with These Are The Days which he sings walking round the stage, microphone in hand. He never quite looks comfortable doing that, always looks more at ease behind the drum kit but his voice is still as brilliantly hoarse as ever. He has a drum duel with Rufus before duetting with the returning Lambert on Under Pressure. Save Me is good but it is the stunning, note perfect, Who Wants to Live Forever, that confirms that this Lambert fellah is the real deal.
Brian's guitar solo includes Last Horizon from his own Back To The Light album. Guitar solos...a slightly dinosaur thing to do these days it has to be said. However this is Brian 'Red Special' May. How can he not do a solo? Ok so solos definitely divide opinion. Some in the crowd use it as the time to get a drink, others stand in awe at a guitar hero in action. For me it does go on too long but I would be disappointed if I didn't get to see May do his thing.
Tie Your Mother Down gets the jumping going (and my dodgy knees hurting) although I soon realise I'm the only one jumping and so self-consciously and rather sheepishly put a stop to my silly behaviour (I forgot us Queen fans aren't as young as we used to be). Rufus Taylor takes the lead drums on that one and shows what a hell of a drummer he is (very Taylor Hawkins like).
I Want It All is powerful; really wish we had chance to see Fred sing that one live, before Radio Ga Ga has the hands in the air. It is poetry in motion watching Queen fans clap along to that song, not missing a beat. Alas Mark crumbled and got his timing all wrong somehow blaming it on the woman in front who couldn't keep time either. His Queen Fan star rating dropped a couple of points after that. Crazy Little Thing sees me trying to dance but failing miserably then its time for the national anthem: Bohemian Rhapsody. It sees the impressive screen behind the band show Freddie and it really is hard to not get a lump in the throat. Unbelievable to think he was only 45 when he died. Even harder to believe it is 24 years ago this year since his sad passing.
We Will Rock You and Champions finish the show as they have since time began (well they are dinosaurs after all). While God Save the Queen is played and the band take their bows I look up to the ceiling and not only manage to swallow half the glitter that is coming down but also curse that I hadn't booked more than one concert….hmmm...I may have to rectify that.
2 hours and 15 minutes that blew the January blues away. If you have your doubts then take it from me Adam Lambert should not be underestimated. Yes by fronting Queen he has undoubtedly done his profile no harm at all in Europe. Yet he has also done the same across the pond for Queen. Lambert is breaking down barriers in America in more ways than one and it is great to see a new showman in town.
I was certainly worried by this collaboration initially but now I just want to go and see them again (I may get to hear Don't Stop Me Now as well). How long this particular partnership will continue we don't know but if it means more shows like this then bring it on.
Ticket: January 17th 2015 / Wrist Band
Ticket Price: £69.00
Set Lists:


text: Humanities Religion & Spirituality Egyptian Creation Myths The Main Cosmogonies of Ancient Egypt Share Flipboard Email Print Religion & Spirituality Christianity Origins & Development The Bible The New Testament The Old Testament Living the Christian Faith Christian Life for Teens Prayers Weddings Bible Devotions Denominations & Movements Funerals Holidays Entertainment Definitions Catholicism Islam Judaism Hinduism Buddhism Latter-Day Saints Taoism Alternative Religion Angels & Miracles Sikhism Holistic Healing Paganism / Wicca Astrology Atheism & Agnosticism View More by N.S. Gill N.S. Gill is a freelance classics and ancient history writer. She has a master's degree in linguistics and is a former Latin teacher. Updated January 05, 2018 Egyptian cosmogonies were more about explaining the order of the world (personified as Ma'at), especially the rising of the sun and the flooding of the Nile, than the creation of mankind. The world would continue its orderly progression regardless of whether or not we mere mortals lived or died, although the kings and queens, as incarnations of the gods, counted, and religious rites symbolically helped maintain the order. During the millennia during which ancient Egypt was a Mediterranean power to be reckoned with, different dynasties came to power, some African, some Asian, and later, the Greeks and Romans. One result of the long, heterogeneous history of Egyptian power is great variety in the myths of ancient Egypt. Tobin ["Mytho-Theology in Ancient Egypt," by Vincent Arieh Tobin. Journal of the American Research Center in Egypt (1988)] says the different and seemingly conflicting creation myths were but different sets of symbols used to "articulate the same reality," rather than factual accounts of how the universe emerged. Two of the versions below have a sun god as the creator. A version not listed below, at Elephantine, has a potter as the creator god. There were 3 main Egyptian creation myths, named for the gods and locations involved, which helped justify the political claims of these cities: Hermopolis - The Hermopolitan Ogdoad,Heliopolis - The Heliopolitan Ennead, andMemphis - The Memphite Theology. Here you'll find information related to the 3 main Egyptian creation myths and the major gods. Go to the hyper-linked articles for more information and the references. 1. Ogdoad of Hermopolis Hermopolis on map of ancient Egypt, from The Atlas of Ancient and Classical Geography, by Samuel Butler, Ernest Rhys, editor (Suffolk, 1907, repr. 1908). Public Domain. Courtesy of Maps of Asia Minor, the Caucasus, and Neighboring Lands The 8 gods of the Hermopolitan Ogdoad were mated pairs from a primordial chaos. Together they produced the world, but exactly what they produced varied with the telling, more so than the variation in the powers of the 8 chaotic deities. They may have produced a mass or an egg or the sun. Although the Ogdoad may not actually be the oldest Egyptian cosmology, the gods and goddesses of it, are thought to have produced gods and goddesses of the Ennead of Heliopolis. Hermopolis Hermopolis (Megale) is a Greek name for this important city of Upper Egypt. Hermopolis was the spot where the chaos gods brought forth life or the sun or whatever, and then later became an important city for the international set, with layers of temples from different religions, and cultural artifacts from the Greeks and Romans. Thoth Thoth. CC Flickr User gzayatz Thoth (or Amun) is credited with stirring up the old chaos gods to create the primordial mass. Thoth is described as a moon god, a cosmogenic god, a god of thunder and rain, a god of justice, and the patron of scribes. Thoth is also the Egyptian messenger god. 2. The Ennead of Heliopolis Detail of Pyramid Text from the Tomb of Teti I, Saqqara (6th Dynasty, First Intermediate Period Egypt). LassiHU The Ennead of Heliopolis was formed during the Old Kingdom period of ancient Egypt by priests in On, the city sacred to the sun god; hence, the more familiar Greek name Heliopolis. The creative force and sun-god Atum-Re generated (through spit or masturbation) Shu and Tefnut, a male and female pair so normal generation could take place. Symbolically, the creation is repeated each day when the sun (god) rises. Pyramid Text The Pyramid Texts refer to the ordering of the gods and the world that informs the Cosmogony of Heliopolis. Atum-Re Ra. CC Flickr User Ralph Buckley Atum-Re is the creator god of the Heliopolitan cosmogony. He was a particular favorite of Akhenaten's father. His name combines two gods, Atum, the god who emerged from the primordial waters to create the other gods, and Re, the basic Egyptian sun god. 3. The Memphite Theology From the Shabako Stone. CC Flickr User kevan The Memphite theology is inscribed on a stone dated to 700 B.C., but the date of the creation of the theology is debated. The theology serves to justify Memphis as capital city of Egypt. It makes Ptah the creator god. The Shabako Stone The Shabako Stone, housed at the British Museum, thanks to a gift from one of Princess Diana's ancestors, contains the story of Ptah's creation of the gods and the cosmos. Ptah Hieroglyph of Ptah. CC Flickr User pyramidtexts Ptah is the creator god of the Memphite theology. Herodotus thought he was the Egyptian version of Hephaestus. Ptah is normally depicted wearing a skull cap. He created by means of the word. Continue Reading


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I have a Trail SL 29ER F4. They have the Shimano HB-M475 hubs. Are they the center lock type? I want to purchase a 2nd set of wheels to setup for street.
My current brakes are Tektro Auriga Comp.
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Etsushi Toyokawa was born in Osaka in 1962. He became well known after starring in a popular TV thriller "Night Head" in 1992. He has been active in movies and TV dramas ever since. Awards he received for his performances include both Outstanding Performance by an Actor in a Leading and Supporting Role Awards from Japan Academy Awards, Best Actor Award for Takasaki Film Festival and Hochi Film Festival. He often chose to work with directors he'd never worked with, to expand his boundaries.
Etsushi Toyokawa's other film appearances include, Isao Yukisada's Kondo ha Aisaika (2010), Katsuaki Motoki's "Inu to Watashi no Ju no Yakusoku / 10 Promises to My Dog" (2008); Kaneto Shindo's "Hana wa Chiredomo / Though the Petals have Fallen" (2008); Yoshimitsu Morita's "Southbound", "Tsubaki Sanjuro / Sanjuro" (2007); Kunitoshi Manda's "Seppun / The Kiss" (2007); Junji Sakamoto's "Tamamoe" (2007); Yasuo Tsuruhashi's "Ai no Rukeichi / Love Never to End" (2007) and Tomoyuki Takigawa's "Hanin ni Tsugu / The Investigation Game" (2007).
Otcho or Choji Ochiai was one of the Secret Base friends. Later he disappeared while working for a trade company in Thailand. He's found working as an underground crime fighter, named Shogun, in Thailand. He goes back to Japan when Kenji contacts him so they can fight Friend together. In 2015 Otcho is put in solitary confinement in Umihotaru Prison, until he risks his life and escapes. He then attempts to assassinate Friend...
Did you read the original manga?
Yes, and I've always been interested in it, because there have been rumours about adapting it for a while, as well as another masterpiece "Monster" created by Naoki Urasawa. Naoki Urasawa is a master storyteller. The way he depicts scenes in his manga is very cinematic. I like the way his drawings are dynamic, but he doesn't use bold strokes. I think that's one of the reasons why the "20th Century Boys" manga is packed with action and dynamic, yet it has class. To adapt it into a movie, I believe that the director is very conscious of the graphic excellence of the manga.
Are there anything you particularly did to play Otcho, the manga character?
The original manga goes into Otcho's background in detail. So I read it over and over. You don't see it in the movie but in the manga, Otcho goes through zen training like a "Dragon Ball" character (laughs). His life is quite extraordinary and in that sense his character is the most fantastic. Most other characters come from regular backgrounds and that puts Otcho in a heroic light. Like Toshiyuki Karasawa said, "20th Century Boys" is an ensemble movie. I figured the character I play could stick out a little. I also postured a lot and positioned my face as Otcho was drawn in the manga. Normally I don't pay attention to storyboards and camera setup plans. But this time, photocopied pages of the manga came with the screenplay so I diligently checked them for reference. Of course this is going to be very enjoyable for those who haven't read the manga but I really don't want to betray the expectations of the manga fans. If we were not truthful to the original manga, it would be meaningless. The principal plan was to follow the manga as close as possible, so I did my best to play the character as closely as it was drawn in manga.
How did you like the location shooting in Thailand?
I went there to mainly shoot the action sequence. I had a long partial wig and a long coat on so it was really hot. Otcho never takes off his long coat. I'd like to ask Naoki Urasawa what's behind Otcho's look one day (laughs).
What do you find most interesting about Otcho?
Otcho is a man who lost something very important in his life. There's something very sexy about him because of that.
About Chapter Two:
"15 years has passed between the first and second chapter of the mega saga of 20th Century Boys. Our toughest challenge in bringing this saga to audiences was to transport them to 2015 in a convincing way. Everything conceivable was done by the director and actors to realise this. Special makeup was applied to age us by 15 years, which also assisted us in our performances. Although it was physically taxing to go through the 2-hour makeup application every day.
The makeup artists and I talked a lot about hair colour options and the affect of ageing on skin. In the comic series of 20th Century Boys, Otcho's hair shows signs of receding in 2015. Initially we wanted to keep as close as possible to the original manga series so I tried on a bald cap. The result was not too convincing so we opted not to go with the balding look.
Otcho in the first movie was a tough, heroic figure who'd gone through a lot in Thailand's ruthless underworld. He continues to be the tough guy in this movie. After he breaks out of Umihotaru Prison, he has many encounters with people with crucial information about Friend and helps solve the 2015 mystery in Tokyo.
Playing his character meant doing many unusual and fantastic things. But in the 20th Century Boys universe, it wasn't unusual so I got used to it when I was playing his character. I really enjoyed all the action-hero scenes. The scenes where my character rescues Kanna at the church and where Otcho confronts Friend alone were particularly exhilarating.
In this movie, Otcho has a sidekick, Kakuta. I got the feeling that the director wanted to bring a buddy element to the film with their relationship and comical interaction. Otcho has very strong feelings for Kanna. He calls Kanna the last hope and really thinks of her as special. I think it comes from his strong feelings for Kenji. Otcho thinks of Kanna as Kenji's legacy.
While Otcho interacts with many characters, there are episodes in the movie where he doesn't feature. It's a complex, big movie. The tone and the pace of the movie are totally different from the first chapter. I hope you'll enjoy this very different 20th Century Boys, set in 2015."
About Chapter Three:
"I did my very best in all three instalments. The shooting of the trilogy lasted a year which, frankly, was gruellingly long (laughs)! Because there were so many actors in each scene, I had a lot of waiting time in between my scenes. It was hard keeping in character during those periods.
While shooting the first two movies, I didn't know how the trilogy would conclude. So my performance involved some guesswork. I had read the original manga but I knew some things had to change. When I finally got to read the final chapter screenplay, I was impressed by the accomplished rearrangement and reconstruction of the original material.
As in Chapter 2, my character is in his 50's. In the final chapter, Otcho's 2 years older. The makeup artist and hair stylist did such a great job ageing me that it made it really easy to get in character. But really the emotions and tensions of each scene were more pivotal than the realistic ageing process of the characters. What the director wanted is entertainment. So I played my character with youthful exuberance despite his age. My character does a lot of stunts, he has to run from Friend's henchmen, climb up a high wall and shoot down flying saucers, which requires a lot of energy! And of course there's the past that Otcho turns a blind eye to. I had to always keep in mind that Otcho is always stuck with his son's death. He has a special bond with Kenji, which is never articulated but motivates him. In the climactic scene where Otcho and Kenji confront Friend I asked the director to do another take because I wanted to get the right emotions. All through the shooting it was very satisfying to be able to perform with incredibly talented contemporaries."
© 1999, 2006 Naoki Urasawa, Studio Nuts, Shogakukan © 2008 "20th Century Boys" Film Partners © 2008 4Digital Media


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It has been done. It's officially December which means time to decorate and go shopping! I put up the girl's tree and decorated my room, this is how it went 😀
Open up the closet and bring out the boxes! Time for set up and some holiday spirit in this house!
I have a lot of ornaments and fun things for my dolls… Don't allow me into a thrift store!
The tree is set up! I cleaned off the branches and pulled them out a tad, time for the best part.
I got the lights set up and they look amazing!!
So majestic and Christmas-y
10 minutes later…
The job is done! The little gifts are under the tree and all of the ornaments are there.
Photo shoot time 😀
All the shiny gifts are under the tree…
Hmm what's that waiting under there?
Some bigger presents hide behind the tree 😉
Looking good Molly!
Molly can't wait for more snow! I'm going to update the picture on this blog soon for winter, so look forward to that! I hope you guys are having a good weekend. I had my first week back from Thanksgiving break, and already I can't wait for Christmas break in about two and a half weeks! When did you guys decorate for the holidays or going to?
See ya next time lovelys!


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Based on the Miramax motion picture by
Juliette Towhidi and Tim Firth
Directed by
Margaret Quarton & Nancy Chastain
When Annie's husband John dies of leukemia, she and best friend Chris resolve to raise money for a new settee in the local hospital waiting room. They manage to persuade four fellow WI members to pose nude with them for an "alternative" calendar, with a little help from hospital porter and amateur photographer Lawrence.
The news of the women's charitable venture spreads like wildfire, and hordes of press soon descend on the small village of Knapeley in the Yorkshire Dales. The calendar is a success, but Chris and Annie's friendship is put to the test under the strain of their new-found fame.
Calendar Girls is based on the true story of eleven WI members who posed nude for a calendar to raise money for the Leukemia Research Fund.


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Mild By Nature, Bitty Bottom Cream, Unscented , 4 oz (113 g)
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Life is just better with animals around! Light up your room and spirit with this art print of an original watercolor painting of a bald eagle soaring through the sky. I hope you enjoy this very personal and meaningful artwork!
Bald Eagle Watercolor Print
25.00$ – 55.00$
SKU: baldeagleprint Categories: Birds, Watercolors Tags: animal art, animal painting, bald eagle, bird, bird art, bird print, eagle, eagle art, eagle art print, eagle painting, eagle print, eagle watercolor
Bald Eagle Watercolor Print
SIZE: choose the size that best fits your budget
SIGNED by the artist
MEDIA: fine art print (the original was painted in watercolors)
FRAMING not included
** all prints are
- printed on archival fine art textured matte paper
- printed using only the finest archival fade proof inks
- shipped within 2-3 business days
- shipped FLAT protected within an acetate sleeve and backing board
- larger print ships SAFELY rolled to prevent bending
Additional information
|10 oz


text:
It isn't enough to sit in your lonely room contemplating all those really
rare records you've found. It isn't even enough to sit at your computer
hawking what you've found on eBay. If you like the music enough to collect
it, you've got to love it enough to want to help keep the music alive.
In the more than 50 years I've been a record collector I've done over 50
music festivals where I organized the kinds of music I collect, and I've
paid to attend a couple of 100 more. I've done radio shows for over 30 years
(I currently do two; one of which has been running for over 16 years). I
have been on the production end of 27 long-play records and some 32 CDs,
all of which feature the kinds of music I collect (vintage, country, blues,
jazz, rockabilly, gospel, and vaudeville). I've produced well over 200
concerts and presentations. I've taught classes at UCSD Extension on vintage
country music and country blues, and I've owned a collector's record shop
for over 36 years.
Now you know where I'm coming from. One other thing you ought to know is
that except on a few occasions, I haven't taken any money for doing what I
do (except, of course, for the shop). Most of the cases that I've taken
money were in the form of a grant. I have a couple of research grants along
the way and the National Endowment for the Arts put together some touring
troupes of old timers back in the '70s. My payment has been mostly in terms
of the great music I've had the pleasure of hearing and take credit for
bringing to San Diego. So, to you other record collectors who actually like
the music you -- and I'm not talking about you guys who are in it purely
for the bucks, since you guys aren't going to listen to me anyway it's
almost a duty to give something back. That means buying records and CDs and
going to concerts, but it also means, for those of us who collect music
outside the mainstream, helping to expose others to that music. If you have
rare stuff that should be reissued, then make your stuff available to those
who'll reissue it. Don't think about getting rich doing it either. The music
isn't there for you to get rich off of. The guy who made the music probably
didn't get rich off it, so why should you? When I look at reissued CDs of
country blues, jazz, old timey, cajun, or whatever, I see the same 15 or 20
collectors (fortunately my name is included as often as possible) who donate
copies of their rare sides for reissue. I know many other collectors who
should be offering up the stuff they have but are content to be members of
"the I have it, you don't club." They ought to be ashamed of themselves
because in 30 years or so they'll be gone. At least some of them will have
heirs who will throw their "lovingly collected" rare recordings into the
garbage and some of that music will be lost forever.
Liking a certain kind of music also means getting involved in keeping that
music in front of the public. Whether it's where music has been (featured
at the Adams Avenue Roots Festival) or where the music is going (like the
Adams Avenue Street Fair), you can be a part of the preservation effort on
just about any level you choose. I might add to those of you who like
old-time music that there's a hell of a lot more work to be done in that
area. Contemporary musicians are more pushy than old-time musicians in getting
their sound around. It's probably been 25 years since an old-time group had
a regular coffee house or club gig. As popular as the festivals on Adams Avenue
are, there is yet to be a club in the Adams Avenue neighborhood that books
old-time music and promotes it. We know there is an audience for it. The
crowds at the festivals tell us that. I don't think a week goes by that
someone doesn't ask me where they can hear some of the artists we present
at our local festivals and clubs. Except for the contemporary artists, I
can't help them. You'd think some of the Adams Avenue coffee houses and
clubs would have old-time music nights but again, it comes back to this
giving back thing. Old-time music is an important part of our heritage and
you damn club and coffee house owners ought to realize that, too. It isn't
enough to have a two-chord singer/songwriter with a ten-person following
while great San Diego traditional musicians like Curt Bouterse, the New
Lost Melody Boys, Mimi Wright, Wayne Brandon, and Clarke Powell never work
anywhere except at the Roots Festival and occasionally the Adams Avenue
Street Fair. The clubs on Adams Avenue ought to be ashamed of themselves,
Well, I've spouted off at just about everyone this time around, but you
all deserve it. Now, get off your butts and go down to the Adams Avenue
Street Fair. If any of you think I might be right, drop by Folk Arts and
I'll tell you a few things you might do to get involved. Go thou and blow now.
Recordially, Lou Curtiss


text:
Variety and contrast an artist uses elements of art to create diversity and differences in design. Contrasting colors, textures, and patterns all add interest to the art work. Highlights of color to the corners or edges of some shapes maybe used to add contrast.
Tuesday, March 17, 2009
Contrast and Variety
Posted by Colan Boggess at 6:23 AM
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Free and easy return
Chaoshaw ... It is made of silver attached to the sides of the head and slips next to the ears to reach the Shaoshau part by means of a bar that passes over the head. The shoulders, despite the paucity and scarcity of Shaoshaw's ornamentation, and the ambiguity that surrounds it is unknown in modern generations and has been used in Nubia. Another type of beads is called Shaoshaw, which is the beads of beads attached to the hair and hanging on my side and the back of the head to the shoulders and the backpacker Burkhart that such an ornament worn by Nubiat in the north of the dir on their heads from the back sharks short trimmed the place of the ornament and mascot together, The source of this ornament is Connect the Asian and African word came Chaoucao sound caused during the movement of women that wear them especially at weddings and events and called upon Alfdajat (Mariko), a Roman word origin
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Know more about the artist of this product
Nubians lovers of heritage, arts and crafts, professions and many developers for the character they own, and crossing through which the beauty of the great Nubia and their customs and traditions and the great heritage which dates back to the era of the Pharaohs authentic. Nubian women since ancient times known as exercising daily for some distinctive handicrafts. It adopted so totally dependent on local resources that largesse of the Nubian region by the source of those resources are agricultural crops and trees that exist in the region as well as other natural sources such as clay mud, which made him an honorary Pots and some limestone and non-calcareous stones that go one way or the other in some manufactures hand. The agricultural crops and trees, the palm tree come in the forefront as human Nubian depends on the Palm in his daily life, depending almost essential, Nubian women marked with the letter colored wicker and called on the workers wicker craft industry Name (Akhawash) craft items wicker often carried out by women, and is transmitted by heredity. Where the mother is keen to teach her daughter the assets of the craft, and in some communities men share with women, especially in the large manufacturing baskets. The wicker dye different colors are available at shops Perfumery and dyeing usually begins to boil water in a large bowl and set the dye is then required to drop the desired colored wicker and leave for 5 minutes then lifted from the water and placed in the shade to dry. The milky white wicker or are such that acquires this color due to exposure to the sun for a limited period of time with evaporated. When wicker manufacturing has to be soaked in warm water to soften even easier, whether wicker Normal or colored assortment because dyeing to Atzul water and then lubricate wicker begins manufacturing work long pigtail and different display plexus by production type and the greater the supply, the number of wicker used papers and has become the industry harder and after Spit-making wicker is formed by product to be workmanship and often are using a broad and long needle (made when mourning specially for this purpose) and thread may be sometimes of wool to decorate I have for often be wicker palm dome, where a resilient References: Khaald Abdul Majid: Specialized studies in the Nubian craftsDiscover More
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text:
October 18, 2010
Small changes make a Big difference!
7 comments:
- Alyse and Bob said...
These are all great things! Thanks for the reminder, and hopefully I can do 10 pushups tomorrow. haha.
- October 18, 2010 at 4:30 PM
- Nancy Moyle said...
Thanks for posting this!! Love it!
- October 18, 2010 at 9:19 PM
- {Gregg and Carli} said...
Thanks Ladies! I hope it was helpful! Keep coming back there is always more!
- October 19, 2010 at 2:08 PM
- Cher said...
Hi Carli,
I'd be happy to give you permission to feature posts from Love Actually for your blog...dating ideas are definitely useful for women! I usually ask all features to include a link back to the post and blog and not include the post's full text or images (as to give them a reason to go to the original source) :)
Good luck starting your new blog---it's a fun adventure!!
- October 19, 2010 at 2:36 PM
- {Gregg and Carli} said...
Thanks Cher, that is not a problem I will be happy to do that! Thanks for your awesomeness!
- October 19, 2010 at 10:16 PM
- Christa Larsen said...
You are awesome Carli! I'm excited to keep up on this blog! I would love an invite to your personal blog... email@example.com. Also, I would love it if you wanted to advertise! If you want to display my button, the url is: http://4.bp.blogspot.com/_CaFQSmXTBqY/TLTMwnS7XEI/AAAAAAAAAeU/x0m-QkUe08g/S220/LDS+Button.jpg - I would be happy to do the same for you if you want!
- October 20, 2010 at 9:43 AM
- {Gregg and Carli} said...
Christa it is not loading the button for me?
- October 21, 2010 at 10:34 AM


text:
iOS Developer in Berlin
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Our Vivy app provides you with a complete overview of your medical data and documents, you are in direct contact with your physicians and you also receive an integrated health and fitness application. With experienced founders and a highly motivated team, the high security standards and features of the app are developed and guaranteed. Our focus is always on customer centricity, less bureaucracy and making a real difference in life of our users.
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High degree of autonomy and crucial role in a highly motivated, talented and international team
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All the equipment you need like a brand-new MacBook Pro, 27" 4k display, etc.
An opportunity to shape a product that may enhance the life of millions of people
Flat hierarchies, as well as short and open channels of communication
About Vivy


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The BAUD has been shown to help chronic pain, improve sleep, stop nightmares, heal traumas deeply rooted in the past and recent emotional concerns of the present. Feelings of anger or shame or urges and cravings are among the many symptoms and conditions it can help.
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Invented by Dr. Frank Lawlis, a pioneer in the field of medical psychology, the BAUD is built around the latest discoveries in neuroscience. You can quiet the over-active neural pathways that are the real source of problems like an out-of-control appetite or a mind obsessed with worry. This same technology has been used in neurofeedback by doctors to treat serious disorders like depression, phobias, substance abuse, OCD and ADHD.
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text:
стр. 55
3 Resuspend the pellet m absolute ethanol and repeat this step twice.
Analysis of HSV-DNA and RNA
4. Dry the pellet, resuspend m 100 pL of DNA extraction buffer, incubate at 37В°C
for l-12 h, boil for 15 min, and take 10 uL for PCR
3.2. Extraction Procedure for RNA
1. Transfer tissue scraped from the slide to a sterile Eppendorf tube containing 0 8
mL TRI and homogenize usmg a Polytron homogemzer.
2 Store homogenized samples for 5 min at room temperature
3 After addition of 0.2 mL of chloroform, vortex samples for 15 s, and store for
2-3 mm at room temperature.
4. Centrifuge samples in a microfuge for 15 mm. RNA is found m the upper phase
5 Precipitate RNA from the upper aqueous phase with 0 5 mL of isopropanol for 10
mm at room temperature. Microcentrifuge samples for 10 mm at room temperature
6. Wash the RNA pellet with 70% ethanol and allow to air-dry.
7. Dissolve extracted RNA m 50 pL distilled water.
3.3. Amplification of DNA
Amplify lo-p,L samples of extract in a final volume of 100-pL m PCR assay
buffer for 30 cycles, at 95В°C for 15 s, 54В°C for 15 s, and 71В°C for 1.5 mtn.
Amplified gB DNA IS 191 bp long, using the gB gene primers described above.
3.4. Construction of Competitor gB DNA
1. A mutant 19 1 bp competitor gB PCR fragment can be constructed, with a HpaII
restriction site 29 nucleotides from the 3' end, by using the wild-type gB
PCR product as template for amplification with the wild-type gB 5' primer
and a new 3' primer (5' AGA-AAG-CGC-CCA-TTG-GCC-AGG-TAG-
TAC-TCC-GGC-TG3') m which nucleotide 29 IS changed from G to C, mtro-
ducmg a HpaII sate internal to the ortgtnal 3' primer. The ampltftcatton
conditions are as described earlier
2. Gel purify the mutant gB product and quantify by optical density
3.5. Competitive Quantitative DNA-PCR
The amount of viral DNA in the extracts is first approximated by titration
against a tenfold dilution series of the mutant gB fragment, followed by a more
precise quantitation by titrating the extracts against a 2-fold dilution series
spanning the first determination.
1. Add 10 uL of extract to samples of a tenfold dilution series of the mutant com-
petitor gB fragment ranging from 100 pg to 1 fg.
2. Amplify the mixtures for 30 cycles using the original primer pair as described
3. Dilute reaction products 200-fold and amplify again for two cycles with radioac-
tive tracer in a 20-uL final volume of PCR Assay Buffer, to eliminate heterodimer
formation (13).
4. Add 20 U of HpaII and incubate the mixture at 37OC overnight.
5. Electrophorese the entire volume on a 4% NuSieve GTG agarose gel m 1X TBE
Ramakrishnan, Fink, and Levine
1234567 12 3456 123456
i -191 bp
MUTANT -162tip
Fig. 1. Competitive Quantitative DNA-PCR of gB. DNA from 2 d, 7 d, and 8 wk hip-
pocampal extracts were coamplified with a twofold dilution series of competitor mutant
gB DNA using gB primers as described in the text. The radioactive amplified PCR prod-
ucts were digested with &"a11 and electrophoresed on 4% NuSieve agarose gels. Gels
were dried and exposed to X-ray film. A representative autoradiograph is shown here. (2 d)
Lane 1, 100 fg of mutant gB DNA coamplified with an uninfected hippocampal extract;
lanes 2-7, twofold dilution series of competitor mutant gB DNA ranging from 100 fg (lane
2) to 3.1 fg (lane 7), coamplified with infected trigeminal extracts. (7 d and 8 wk) Lane 1,
100 fg of mutant gB DNA coamplified with an uninfected hippocampal extract; lanes 2-6,
twofold dilution series of competitor mutant gB DNA ranging from 100 fg (lane 2) to 6.25
fg (lane 6), coamplified with infected trigeminal extracts.
buffer. Dry the gel and expose to X-ray film (Hyperfilm-MP, Amersham, Arling-
ton Heights, IL) at -70В°C.
6. Visual comparisons of the wild-type and mutant bands allow for a rough approxi-
mation of the amount of viral DNA in the extract.
7. Add 10 & of extract to an appropriate twofold dilution series of mutant competi-
tor gB fragments, usually from 100 to 3.1 fg.
8. Repeat steps 2-5. A representative autoradiograph is shown in Fig. 1.
9. Count the amount of radioactivity in each band using a system like the AMBIS
Radioanalytic Imaging System.
10. Prepare standard linear regression curves by plotting net counts per minute for
each sample in the dilution series against the amount of input mutant gB DNA in
the series. A software program like the Graph PAD INPLOT software program
(Graph PAD Software, San Diego, CA) may be used for this. Using the regres-
sion coefficient obtained from the standard curve and the net cpm from the wild-
type bands, the point of equivalence is determined and the amount of gB DNA in
the original extracts calculated.
3.6. Amplification of RNA
RNA templates are amplified using a combined RT-DNA amplification
method (9,24) in a single tube, using a single buffer system.
1. Treat extracts with DNase I (1000 U) for 60 min at 37В°C to destroy the DNA template.
2. Incubate extracts in a final volume of 100 mL of RT-PCR assay buffer, at 37В°C
for 30 min to permit reverse transcription.
Analysis of HSV-DNA and RNA
73 PROMOTER 6 PRIMER (IA'IJ
5' CC-TCG-AAA-TI'A-ACC-CTC-ACT-AAA GAC-AGC-AAA-CCC-GTC-AG 3'
Fig 2. Schematic of the use of a 12-bp bridge oligonucleotide to stabilize the T3
RNA polymerase promoter and the 5' LAT primer for ligation
3. Amphfy using LAT primers at 95В°C for 1 mm and 60В°C for 1 min for 30 cycles,
followed by a single extension at 72В°C for 10 min. This results m a 195-bp prod-
uct with a BsaHI restriction enzyme site located 2 1 nucleotides from the 3' end
3.7. Construction of Competjtor LAT-RNA
A mutant LAT-PCR product can be constructed in which the cytosine at resi-
due 22 from the 3' end 1s converted to thymidine, resulting in the loss of the
BsaHI site. An oligonucleotide codmg for the T3 RNA polymerase promoter (5'
GCT-CGA-AAT-TAA-CCC-TCA-CTA-AA 3') 1s ligated to the 5' end of the
LAT 5' primer (5' GAC-AGC-AAA-CCC-GTC-AG 3') using a 12-bp brtdge oli-
gonucleotide (5' TGA-TTT-CTG-TCG 3') complementary to SIXbasesof the T3
promoter oligonucleotide and SIX bases of the LAT 5' primer as shown in Fig. 2.
1 Treat 5 pg of LAT 5' primer with 10 U of T4 polynucleotide kinase Extract the
reaction products with phenol-chloroform, precipitate in ethyl alcohol, dry, and
resuspend in 10 pL autoclaved distilled water
2. Ligation of the T3 promoter oligonucleotide and the kmased LAT 5' ohgonucle-
otide m the presence of the bridging oligonucleotide (5 pg each) IS accomplished
using 30 U of T4 DNA hgase m a final volume of 30 uL for 12 h at 14В°C.
3. The T3 promoter-5' LAT ohgonucleotide ligation product (5 JJL of the ligation
reaction mixture) is used m combmation with the 3' LAT mutant primer (5' ACG-
AGG-GAA-AAC-AAT-AAG-GGA-EGC-C-3') to amplify the wild-type LAT
fragment creating a T3 promoter-mutant LAT DNA fragment that has lost the
BsaHI site 22 nucleotides from the 3' end of the PCR product.
4. Electrophorese PCRproductson a 1% low-melt agarose 1X TBE buffer, ex-
the in
cise the corresponding band and confirm the presence of the mutation by BsaHI di-
gestion. The wild-type 3' LAT primer anneals downstream to the point of mutation,
permitting the amplification of the mutant LAT using the original LAT primer pair.
5. Confirm thenatureof theT3-mutantLAT construct PCRamplification
by usingtheT3
ohgonucleottde as the 5' primer and the 3' LAT primer and the original primer pan.
Both primer sets should amplify a mutant LAT fragment that has lost the BsaHI site.
6. Subject 5 uL of the T3-mutant LAT DNA template to in vitro transcription using a T3
RNA polymerase kit (Promega, Madison, WI) in a final volume of 200 pL at 37OC
min according to the directions of the manufacturer After 60 mm of incubation, add
20 more units of RNA polymerase and continue the reaction for an additional 60 mm
Ramakrishnan, Fink, and Levine
MUTANT -195 bp
WILD TYPE 174 op
Fig. 3. Competitive Quantitative RT-PCR of LAT-RNA. RNA from 2 d, 7 d, and 8
wk infected hippocampal extracts were,reverse transcribed and coamplified with a two-
fold dilution series of competitor mutant LAT-RNA using LAT primers as described in
the text. Radioactive RT-PCR products were digested with BsaHI and electrophoresed
on 4% NuSieve agarose gels. Gels were dried and exposed to X-ray film. A representa-
tive autoradiograph is shown. (2 and 7 d) Lane 1, RT-PCR products from infected
hippocampal extract after RNase treatment; lanes 2-6, RT-PCR products from a twofold
dilution series of competitor LAT-RNA, ranging from 50 fg (lane 2) to 3.1 fg (lane 6),
added to infected hippocampal extracts; lane 7, RT-PCR products from infected hippoc-
ampal extract; lane 8, RT-PCR products from infected hippocampal extract without
addition of reverse transcriptase. (8 wk) Lanes 1-5, RT-PCR products from a twofold
dilution series of mutant LAT-RNA, ranging from 50 fg (lane 2) to 3.1 fg (lane 6), added
to infected hippocampal extracts; lane 6, RT-PCR products from infected hippocampal
extract; lane 7, RT-PCR products from infected hippocampal extract after RNase treat-
ment; lane 8, RT-PCR products from infected hippocampal extract without addition of
reverse transcriptase.
7. Digest the DNA template with 10 U of RNase-free DNase, for 60 min at 37В°C.
Extract the reaction products with phenol-chloroform, precipitate with ethyl
alcohol, dry, and resuspend in 100 pL of autoclaved distilled water. Quantitate
RNA by measuring optical density.
3.8. Competitive Quantitative RT-PCR
1. To obtain a first approximation of the amount of LAT-RNA in the brain extracts,
5 pL of extract is mixed with a IO-fold dilution series of mutant LAT-RNA rang-
ing from 1 pg to 1 fg and subjected to RT-PCR as described.
2. Amplify the samples for 30 cycles, dilute 200-fold, and following reamplification
for an additional two cycles, electrophorese the entire reaction mixtures in 4%
NuSieve GTG agarose gels, dry the gels, and expose to X-ray film, from which
visual estimates of RNA quantities can be made.
3. To arrive at more accurate determinations of the amount of LAT-RNA in the ex-
tracts, coamplify 5-a samples with an appropriate twofold dilution series of com-
petitor mutant LAT-RNA ranging from 50 to 3.1 fg, using the same procedures as
described above.
4. Process the RT-PCR products, quantify radioactivity using the AMBIS system
and analyze counts by linear regression as described for the viral DNA determi-
nations. A representative autoradiograph is shown in Fig. 3.
Analysis of HSV-DNA and RNA 363
3.9. In Situ PCR
1. Latently infected animals are perfused with 4% paraformaldehyde, the ganglia
embedded m paraffin, and cut mto 6-p sections on a mlcrotome
2. Sections of infected trigeminal ganglia on glass slides are deparaffinized m xylene
(3 x 2 min)
3 Sections are successively rehydrated with graded ethanols m the following order:
100% ethanol (2 x 2 mm), 70% ethanol (2 min), and 50% ethanol (2 mm)
4. Wash sections in PBS (pH 7.5) for 5 min, twice.
5 Sections are then treated with 1% HC 1 m PBS for 5 mm and then washed m PBS
(3 x 5 min).
6. The sections are rinsed m PCR Buffer II (3 x 5 min)
7. 25 PL ofln situ PCR reaction mixture is layered onto the sections, which are each
covered with a glass cover slip and sealed using nail polish, taking care to ensure
that the polish does not seep into the reaction mix.
8. PCR amplification 1s carried out in a BloOven II Thermal Cycler (BioTherm,
Fairfax, VA) m two stages, first for 3 cycles at 92В°C for 1 mm, 54В°C for 30 s,
and 72'C for 30 s, followed by 25 cycles at 92'C for 15 s, 54'C for 15 s, and
72В°C for 15 s.
9 After amplification, the cover slips are removed and the sections washed succes-
sively with 1X SSC (2 x 5 mm), 50% formamide in 1X SSC (3 x 15 min, 56"C),
and 1X SSC (2 x 15 mm)
10. Following a rinse in Trls-buffered saline (pH 7 5) and 5% normal goat
serum, the dlgoxlgenln-labeled amplified DNA 1s treated with an antl-
dlgoxlgenm antibody conjugated to alkaline phosphatase (1:250 Boehrmger
Mannheim, Mannhelm, Germany), and visualized with BCIP/NBT (Vector,
Burlmgame, CA)
11. Color development 1s monitored visually, and stopped typically after approx 30
min, by washing with 0. 1M Tris-HC 1, pH 7 5, 1 mM EDTA. Typical positive
neurons are shown in Fig. 4A
3.70. Controls for the In Situ PCR
A number of controls are required to determine that the zn situ PCR results
are specific for the HSV- 1 gB gene sequence.
1. In sztu PCR 1s carried out using gB primers and uninfected ganglia to show
absence of any labeled nuclei (Fig 4B)
2. Using a primer pair for the HIV Tut gene not present m the tissue, no 1˜1 sztu
signals should be detected m infected ganglia (Fig. 4C)
3. DNase treatment of sections from infected ganglia prior to PCR should com-
pletely eliminate the PCR signals (Fig. 4D)
4. Finally, DNA extracted from sections of infected ganglia after PCR 1scompleted
should hybridize to gB specific probes in Southern blot analyses. Smgle radloac-
tive bands of the expected length should be observed (Fig 5)
Ramakrishnan, Fink, and Levine
Fig. 4.1˜ Situ PCR of HSV- 1 DNA in Trigeminal Ganglia. (A) In situ PCR of a
6-p infected trigeminal ganglionic sections with oligonucleotide primers for HSV- 1
gL3DNA sequences and digoxigenin-labeled nucleotides at 8 wk postinnoculation. (B)
Control, showing uninfected ganglion amplified in situ with HSV-1 gB primers. (C)
Control, showing 8-wk postinoculation ganglion amplified in situ with primers for
HIV tat. (D) Control, showing 8-wk postinoculation ganglion, amplified in situ with
primers for HSV- 1 gB gene after overnight DNase-1 treatment. Bar = 100 u.
4. Notes
1. PCR: A number of factors can contribute to nonspecific amplification. These can
a. Contamination of PCR reagents: Use the best quality of reagents possible,
and use them exclusively for PCR. We routinely aliquot out all our solu-
tions and freeze them away at -20В°C. We also use aerosol-resistant tips
for pipeting to minimize crosscontamination. Designate one area in the
lab exclusively for PCR work. When possible, DNA and RNA samples are
prepared in separate rooms. In addition, it is absolutely essential to run suit-
able negative controls (i.e., without target sequence) each time an experi-
mental PCR is performed.
b. Titrate the 7'aq polymerase with the specific target. Too much enzyme can
result in nonspecific background.
c. Titrate primers from 50 ng to 1 yg.
Analysis of HSV-DNA and RNA 365
стр. 55


text:
I met Andy at a friend's birthday party about 2 months ago. He was really cool! Genuinely friendly, fun to be around, and after only a few minutes conversing, we quickly spotted some common interests: French, France, England, love for Persian people, traveling..
We added each other on Facebook, liked each other status, he invited me to a get-together where I met his girlfriend and friends. And next thing you know, he decides to support my run and contribute to my fundraising for BCNA.
Someone I only met 2 times! How incredible is that ?! I think that says a lot about Andy. I am glad he is part of that adventure and, cannot wait to get to know him more!
Thanks Andy!
Please be part of my adventure, support my run and more importantly donate for Breast Cancer Network Australia now: http://ow.ly/qUFoZ


text:
Discussion in 'Getting Started/New Member Help' started by makomako, Apr 9, 2008.
the only way I have seen is to click on new member help. is there an other way?
If you go to the main forum index http://board.midibuddy.net/index.php, the black bar on the top of the page has a drop-down menu that will allow you to post new threads.
thank you. It helps me a lot.
Yep, thanks, thats good idea.
I tried some possibilities ( etc.) but with no success.
Separate names with a comma.