text:
Your Local One Off Cleaning Specialists in
Intensive Agency Approved One Off Cleaning Services in
Call Us On: 0208 942 2819
Toll Free: 0800 689 8989
After Office Hours: 07907 004090
From Abroad: +44 7907 004090
Request A Quote Online: Request A Free No Obligation Quote
Email Us: firstname.lastname@example.com
Are you looking for professional deep cleaning services in Area and want to get your property fully cleaned to highest possible standards? You are probably on a right page then. We are your local cleaning company offering bespoke home and office deep cleaning services at highly competitive rates.
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You may call us on 0208 942 2819 or on 0800 689 8989 in order to book the service. If you are calling us after office hours then please call on 07907 004090
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There are several other services we can provide when it comes to cleaning, handyman services, and more, please browse through our website or give us a call today!
Dear Luqman, Thank you for sending an amazing team, when one of the most reputable company in London have failed and refused to do re-clean you guys came in and you guys did a great job! I will never use another company but you guys for all our move in or move out cleaning needs! Thanks once again, I and my Mrs are very pleased with how you guys work Cheers Isleworth, London, UK
Cheap cleaning service yet so professional – Quick turn-around time, great support and cleaners very punctual. Fulham Broadway, London
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End Of Tenancy Cleaning Oxford Reviews = Dear Luqman, A big thank you for offering us an amazing end of tenancy cleaning services in Oxford on Saturday. Your staff was really a pleasure to work with. They even dropped us at our new property. I can safely say, I have found professional end of tenancy cleaners in Oxford for highly affordable prices. You guys were stars! I would not hesitate to recommend your end of tenancy cleaning oxford services to my friends and family! If you guys are in town, please join us on lunch sometime! See ya! Luciana Oxford, Oxfordshire, UK
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I am extremely pleased with their professional end of tenancy cleaning services, eye to detail, pleasing personalities and extreme politeness. Thanks for all your help Wandsworth, UK
The best cleaners I have worked with in my lifetime, great service!


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Rowley Turton has joined Leicestershire County Cricket Club's 1879 Business Club.
The 1879 Club was formed in 2015 and provides local businesses with advertising at Leicestershire's Fischer County Ground for Vitality Blast fixtures, Specsavers County Championship games and Royal London One-Day Cup matches. For the £1,500 price tag, sponsors also receive two match tickets to watch a selected England international match, and social media exposure.
Tracey Branson, corporate partnerships manager for the club, said: 'We are extremely happy to have Rowley Turton on board at the Fischer County Ground as a new member of the 1879 Club. It is a well-known and highly respected company within Leicester, and will be a welcome addition to our business club.'
Scott Gallacher (pictured left), director at Rowley Turton, said the partnership would allow his firm to strengthen its client relationships and improve its standing in the local area. 'As a Leicestershire business, the 1879 Club offers us an excellent opportunity to strengthen our relationship with our existing clients, fellow professionals and our local community,' he said.
Rowley Turton was formed in 1996 at 20 Friar Lane, Leicester, by managing director Alan Turton. According to E. E. Snow's A History of Leicestershire Cricket, Leicestershire CCC was actually created at the same address, 117 years previously in 1879. Turton appeared as a New Model Adviser® cover star in 2016.

subset: commoncrawl


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Our annual tradition is to do a canvas painting for Gran every year for Mother's Day. Gran has them all proudly displayed in the dining room. The first one Wee Picasso was just over 2 months old.
View the 2010 painting here - 2010 painting for Gran
I will have to take a picture of Gran's wall of art someday.


text:
Quarry Screen Mesh
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Quarry Screen Mesh & Crusher screen Mesh material
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our customers. We hope to build up friendly
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Welcome to visit our factory!


text: That makes our entire company proud. Our long-term and new clients are our greatest fans! We'll let them do the talking about our fantastic company. Our West Coast location (Redlands, California) has been referred to as West Coast Derm Billers or WCDB and our East Coast location (Casselberry, Florida) has been known as Dermatology Billing Associates or DBA. You'll hear our clients' testimonials refer to these two locations by their previous names. They are both now known collectively as The Inga Ellzey Billing Companies. No matter what you call us, our clients all call us "The Best!"


text:
Fortnite has arrived on mobile platforms, with Epic making its battle royale game cross-platform with PC and consoles.
The battle royale shooter goes from strength to strength in 2018, with the mobile version for iOS and Android joining PC, PS4 and Xbox One.
There's some confusion about how a mobile version works with other formats, which devices are supported and when exactly it's available, so we're going to help clear that up.
When does Fortnite on mobile launch for Android?
Fortnite mobile will be coming to Android devices in the future. Epic's official response is "support for Android will be coming in the next few months". The good news is that the release of Fortnite on iOS is now out of the way, so all effort is on the Android port.
The following is a list of Android compatible devices that Epic has said it will support:
- Google Pixel 2 / XL
- Huawei Mate 10 / Pro / Lite
- Huawei Mate 9 / Pro
- Huawei P10 / P10 Plus / P10 Lite
- Huawei P9 / P9 Lite
- Huawei P8 Lite 2017
Access to Fortnite on Android is likely to be invite only as it originally was for iOS, as Epic gets its tech straight, so expect a limited sign-up process in the first couple of weeks.
How to get Fortnite mobile on iOS and what are the compatible devices
Originally, Fortnite on mobile for iOS was invite only. But this is now no longer the case. You just need to simply navigate to the App Store and download the game to start playing.
To play Fortnite on mobile you'll need iOS 11 on at least an iPhone 6S/SE, iPad Mini 4, iPad Pro, iPad Air 2 or iPad 2017 device.
Here'a a list of all iOS compatible devices:
- iPhone SE
- iPhone 6S / 6S Plus
- iPhone 7 / 7 Plus
- iPhone 8 / 8 Plus
- iPhone X
- iPad Mini 4
- iPad Air 2
- iPad 2017
- iPad Pro
Is Fornite mobile on iPhone 6?
There's been some confusion as to whether or not Fortnite works on the iPhone 6. Apple originally had the iPhone 6 listed as a compatible device but that was an error. We've check with Epic Games and Fornite mobile does not work on the iPhone 6. You will need the iPhone 6S or 6S Plus to play Fortnite mobile.
Fortnite mobile: how to invite friends
Each user has three invite codes for Fortnite mobile so you can send them to friends and play in a squad if you want to. You'll see a notification in the lobby on the right hand side of the screen. To send out invite codes do the following:
- Launch Fortnite
- Wait for the game to connect to the Fortnite servers
- In the Fortnite Lobby, tap the Invite Friends tab
- Tap Share Invite Code
- Tap the method you want to share the Invite Code: either directly to an Epic account or via email
- Tap send
Once your friends have accepted the invite and signed up for an Epic account they'll be automatically added to your friends list.
Is Fortnite on mobile different to PC, Xbox One and PS4?
Fortnite Battle Royale mobile is the same game as it is currently on PS4, Xbox One and PC. We've played it, and it's a pretty smashing port of the original game. That means 100 players on the same map, with the same loot and progressions, complete with weekly challenges and updates.
You can check out 9 essential tips for Fortnite mobile, and we also went the whole hog and had Fortnite mobile face-off with PUBG mobile because we're thorough like that.
Even better news is that Fortnite mobile supports cross-platform play with PS4, PC, Xbox One and Mac. This means game play and game progression will work and be saved across those formats.
The post Fortnite mobile: when is the Android release date, what are compatible devices and how do you sign up? appeared first on VG247.


text:
This cruise left from Tampa, which is one of our favorite ports to leave from. The path to the Gulf of Mexico is a long one and there is much to see on the way.
|Daniel did a painting of this street. You can see it here on his blog.
❧ Silke
|Daniel did a painting of this street. You can see it here on his blog.
Key West looks oh so quaint -- like visiting a different era. Love those famous cats!ReplyDelete
Some great pictures of great places there! I am puzzled by the red ribbons on the white fence. Do you know why they were there?ReplyDelete
Liebe Silke,
vielen Dank für deinen ausführlichen Reisebericht. Besonders gefällt mir der kleine Leuchtturm.
Ich wünsche dir eine gute Zeit.
Allerbeste Grüße


text:
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text:
UK Aviation Movies
Aviation in motion
A few departures from RIAT 2012.
Various displays from F-16s, F-18 Super Hornet, French AF Rafale and the RAF Tornado Role Demo and Typhoon.
Some highlights from the from RIAT 2012 arrivals days. Shot with a Sony HDR-SR11.
A older movie from the archive.
This footage is sitting inside one of my earlier RIAT videos but I thought it was time to bring it out from hiding!
Shot on July 7th 2012 on a Sony HDR-SR11E.


text:
Cammile gets ready to leave for a lunch appointment when she sees the garden tractor parked behind her car. She tries to push it out of the way knowing it won't run because there is no key. Dressed in a stretch cotton Guess dress and expensive peach Casadei high heels Cammile Tries to push the tractor out of the way. She struggles to move the little mower as her thin Casadei stilettos bend and almost crack under the pressure of her straining. As the tractor starts to move she does not notice the sticky greasy mess it had left behind, a slippery sticky mess that her fancy high heels were about to get ruined in. Soon here heels were attacked by the goo! Cammile can't believe it.. she is slipping in this sticky mess! She hangs on to the tractor and figures if she is in it this far she might as well keep going. As she pushes she looses her footing in the goo and her pretty bare feet pop out of her heels and wind up in the mess. Because the pavement is very warm Cammile is forced to put her sticky foot back into her fancy expensive Casadei heel. Still she cant get a grip an before you know it her other foot follows the others fate.
See Cammile's feet get sticky and her beautiful heels get trashed in this HD video shot in 4K with quality sound for computers with graphics cards for smooth play.
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text:
A conversation between Marina Abramović and Harold Koda.
curated by Silvia Mella
One thing that I find really inspiring is when heavenly bodies, whom would otherwise never come into close contact due to their orbits cross paths or align together and align with the unconscious purpose of stimulating and disrupting each other to expand both their horizons. That is the same awe with which I approach these two titans meetings. They had never meet before, but I knew it that they would have so much to share with each other.
Harold Koda: I notice your make up is very symmetrical. Is there something about symmetry that relates to beauty or do you have any kind of standard or codified ideas about what constitutes beauty?
Marina Abramović: I think beauty is overrated. There are so many factors that go into whether or not an individual perceives something as beautiful. I think in the past what was considered beautiful doesn't quite apply today.
H.K.: It's always changing and it's always unstable.
M.A.: Exactly, it's inconsistent. I have a very big problems with things being symmetrical. I would have recurring dreams as a child of symmetrical arrangements of seats on left and right with bells on them, and one bell missing would ruin the symmetry of the airplane corridor. Another dream would be an army with all the soldiers uniforms perfect, and I would go and remove a button from each of them to break the symmetry. So I feel like as an artist, my role is to break the code and create new ones.
H.K.: Do you think that this relates more to you introducing chaos or just somehow establishing a new order?
M.A.: I think that breaking the codes of symmetry is more about creating your own order, to propose a new solution for order. Especially when I was a young artist, I had to find a way to express myself and performance was my best tool. I didn't like theater, it was the enemy of performance because it's in a box and is artificial. Performance is something really true and in the moment: you have to break all the rules and create new ones, then maybe you can start to tolerate old ones again. Now I appreciate theater much more.
H.K.: Do you find that when returning to what you rejected [with a new point of view], it's completely altered by what intervened?
M.A. : Yes, I think that you return to things with a brand new perspective, similarly to how you have to sort of hate your parents to an extent growing up, but realize what they told you growing up makes more sense for you later on.
H.K.: What I noticed about creative personalities, being a curator and vouyuer of the creative process, is that creatives never truly relinquish control. What may appear outwardly to others as chaos, or asymmetry is really a new order imposed by taking a different form.
M.A.: My mom was obsessively ordered, when i was a child, she'd even wake me up to tell me that I was sleeping too messily and to fix my bed which is completely insane. So now when I go to hotels, the cleaning people think that I don't even sleep because I'm so still and don't wrinkle anything.
H.K.:(Laughing) How's your underwear drawer?
M.A.: Completely organized by color. Now I have to be organized in regards to almost everything. The ideal places for order are sanitariums, prisons, and monasteries because the order is so perfect that your mind can wander free, even if they're not all ideal living environments.
H.K.: How do you work with others or deal with situations in which you are not in a position of power?
M.A.: I tend to let the person have control because I think as human beings, one of our problems is that we constantly go after what we like or are familiar with, and so we repeat the same mistakes. When I get an idea, if I have this sensation of fear and panic because it is completely new territory, I get excited. If an idea seems too nice and pleasant, I drop it. I'm not interested in it because I know the process will not bring any change.
H.K.: The thing about beauty is that just the word suggests a sort of complacency or standard that is shared whereas if you say "repulsive," it could be so many more things. Beauty seems to be more by consensus or at least what the majority would say is the consensus.
M.A.: When I was 24, I made a piece called "art must be beautiful," and it was really misunderstood. Art has to be disturbing, ask new questions, has to predict the future, raise awareness in the people viewing it. These criteria adds to its complexity and to its adaptability for others so that they can take what they will from it. If art is too political, people will find it relevant today and the next, old news.
H.K.: One of the things I found fascinating is that every so often, magazines will take a bunch of pictures of women who are considered beautiful at the time and super-impose them over each other to find come up with some sort of generalized face. In the end you are stuck with what a plastic surgeon might consider beautiful.
M.A.: It's horrible. Beauty comes from inside. What I've always found fascinated about being Slavic and coming from Eastern Europe is Russian icons. The beauty or light comes from inside them instead of outside. That inner-illumination is like divine presence.
H.K.: That's a interesting point: an icon has that power and is very schematic, and people are able to project themselves onto it and identify with it better. When it's too photographic or too representational of real life, it lacks that power. To me it's more of an abstraction of an ideal.
M.A.: Yes, that inner light and the idea divine presence I find very very powerful.
H.K.: So are you a theist?
M.A.: It's really complicated because I come from a Communist background, but my grandmother was highly religious, and my grandfather was the Patriarch Varnava of the Serbian Orthodox Church , and my mother and father were national heroes from World War 2, with my mother also being Director of the Museum of the Revolution and Art in Belgrade. I'm a strange mixture of the deeply religious and artist communities. As a religion though, what attracted me the most is Tibetan Buddhism, and not just the beliefs but the philosophy behind it as well.
H.K.: I was raised as a Buddhist, but I found it too hard to believe. Nonetheless, it made me conscious of the fact there is no way to arbitrarily state there is nothing or that another's beliefs are wrong. I'm more comfortable with the plastic world, and empiricism, and the Age of Reason, but I don't see truth in any kind of hierarchy.
M.A.: I just came back from Brazil. I was investigating places of power in nature like mountains, valleys, waterfalls, volcanoes, and their energy and its spiritual connection with the people who live near them; their shamanistic ways. Meeting these people and feeling that energy...I made over 100 hrs of film!
H.K.: Have you been to Ise? It's a Shinto shrine in Japan.
M.A.: I haven't been to that one in particular, but I have been to others.
H.K: There's something about the presence of nature that has been cultivated in a way to elevate it that is so deeply moving. You enter the main shrine in the same way that you would others, but then you see the use river and riverstones, and how clear the water is. There are granite steps that go into the water with fish swimming over them and it's incredible. There's this transparency of your environment.. you have to see it.
But anyway, do you think beauty is more about light or shadow in terms of conventions we use to identify it?
M.A: I think it's a mixture of both. You can't have one without the other. Regarding religion, though, I'm more spiritual than a practitioner of any religion. I've had experiences with incorporating spirits after I went to visit this man called John of God whom operates on people with no anesthesia.
H.K.: Tell me about it. Did he actually have you present while he was operating on someone?
M.A.: Yeah, of course. It's a thing where there are a lot of people present, but I had asked him six months or so before if I could film it, and he said no, but when he saw me, he said "I can't unless I ask the permission of the spirits I invoke." He got permission, and I was able to witness one of his operations. It shook me. It was very powerful.
H.K.: I believe that places of both design and nature are beautiful and have energy.
M.A.: Yeah, and also of note is that churches and other buildings had historically been built on or near places of power or where people felt a spiritual connection, and I feel like we've lost that to an extent.
H.K.: How did you go into fashion?
M.A.: When I was growing up, it was definitely a "no-no" to be into fashion as an artist, because it represented vanity.
H.K: ...and the ephemeral and temporal.
M.A.: That...and something insubstantial, cheap, or vulgar. I remember in the 70s even wearing nail polish and lipstick as an artist was frowned upon.
H.K.: I guess because it was bourgeois and associated with a mindset of conventional beauty.
M.A.: There was a bit of collaboration with Dadaists and fashion and Surrealism, but there wasn't much. Like Coco Chanel: making costumes for theater and such, but yeah, not very much crossover. For me, it was really when I was between 40 and 50, and I was sad and feeling abandoned by the man I was in love with. I spent more time on myself: I bought a beautiful Yamamoto jacket, got my hair done, and I asked myself "What's wrong with this?" I felt good about indulging myself.
H.K.: What were you into wearing before? Was it intentionally transgressive?
M.A.: Not really, I wore pretty much white shirts and trousers, nothing special. Performance artists in the 70s–there were only really two appropriate looks, dirty white or dirty black.
H.K: In NY there was a Yugoslavian designer, Zoran, and his approach to fashion was all about minimalism. He loved color, but everything was modular and seamless or with straight seams, and he kept pushing it and making it simpler and simpler while using the most luxurious fabrics. Are you familiar with him?
M.A.: Yamamoto was the first designer I really bought. He had a documentary, and he was saying "In old days if you were sleeping, you would hang your clothes up, and if you woke up and forgot who you were, you would know by the clothes in front of you your role in society." He was very much influenced by Russian clothing not necessarily Japanese like you'd expect. With Issey Miyake even, they would ask him why he designed such large dresses, and he'd say it's so important that there is space between the fabric and the body for your spirit to leave: that got me thinking about fashion in terms of truly original designers and the others, and I was really interested in original designers.
H.K.: Who are the Originals you admire most at the moment, if you had to make a short list?
M.A.: I'd definitely put Riccardo (Tisci), my friend of course, and Yamamoto, because I love him, but Rei Kawakubo of Comme des Garçons–her clothes, never mind that you can wear them, are art in the way that they are detailed. My favorite was a piece with strange buckles and hinges all over the body.
H.K.: Right, because she is someone who advocated for originality over any preconceived ideas of how things should be.
M.A.: Her interest was to create something new over something marketable.
H.K.: When she did her bump dress that looked like there was a tumor or growth coming from the side–(M.A. interjects)
M.A.: That was also a favorite of mine.
H.K.: Merce Cunningham had her do some costumes for his dance, Scenario.
M.A.: I saw that ballet. I loved it. Oh, I also love Margiela.
H.K.: Did you ever see his Barbie collection? You know with Barbie dresses, the snap has to be the same size as a normal dress despite it being miniature, for our hands. Well, he took the simplistic design of these dresses he blew their size up 100 times to life-size. Everything was so large but still so simple because on a doll you didn't have the same refined cut, it was beautiful.
M.A.: There was another exhibition he did where beside each piece on display, there was a piece of paper that noted number of hours it took to make it. 300, 1000, etc..time is so important to both art and fashion, and I found this really relevant to what I do as a performance artist.
I'm really good friends with Riccardo (Tisci). I made a piece with him called 'The Contract.' I said to him, "Riccardo, let's make something together. Is it true that fashion takes from art? Well, I'm the art, and you're the fashion, just suck my tit!" and that's exactly what he did. I loved it!
H.K.: I saw that as well. It definitely got people talking. Regarding beauty: In your early works, did you wear makeup?
M.A.: Never. During my performances I still don't wear makeup, and I don't use dresses. I sort of have this robe that I use to keep warm but nothing else. However, I'm delighted to enter this other world after performances where I love to wear things. Let me show you the jacket Riccardo made for me: isn't it amazing? It's a pleasure to wear.
I'd get a lot of criticism by my generation for my interest in fashion, but I asked myself "why shouldn't art meet fashion and beauty"? Art is supposed to push and cross boundaries.


text: School custodian returned to work drunk, sexually assaulted co-workerBut Ottawa-Carleton District School Board wasn't justified in firing him, says Ontario Arbitration board11/21/2005|employmentlawtoday.com The Ottawa-Carleton District School Board wasn't justified in firing a custodian who returned to work drunk after hours and sexually assaulted a female co-worker, an Ontario Arbitration Board has ruled.The board awarded Franco D'Angelo, who was chief custodian at a school, his job back, albeit at a different school than the one where the victim worked.What happened the night of the assaultThe alleged assault took place on Feb. 3, 2004, at about 8 p.m. D'Angelo left work a few hours earlier, at the end of his shift, and returned to the school in a drunken state, having spent the intervening time at a local bar.He used his keys to get into the school, where he sought out a colleague — a regular part-time custodian, described in the arbitration decision as "petite," who had been employed by the school board since 2000.It is alleged that D'Angelo, who stood six foot two and weighed 225 pounds, engaged in a "frightening sexual assault" in an isolated area of the school, in the course of which he lifted up the victim and hugged and kissed her.Following an investigation, D'Angelo was suspended and his employment was terminated.D'Angelo said he had no recollection of the assault on his co-worker. He said he had been taking prescription medications which, combined with the alcohol, had had an unexpected affect on him.D'Angelo had been with the school board since 1988. His employment had been free of discipline. His normal workday was from 6:30 a.m. to 3 p.m.At the time of the assault, he had several health problems. In addition to hypertension and sleep apnea, he had degenerative disk disease for which he took pain medication and a muscle relaxant. He had been warned he would become drowsy if he took the muscle relaxant and alcohol at the same time, but said he had done so frequently and had been able to cope with the effects.His degenerative disk disease got worse when he shoveled snow, he said, and Feb. 3 was a snowy day. It was snowing when he started work, and he took the muscle relaxant (Flexeril) three times during the day. It was a busier than usual day, because of the snowfall and because some additional preventive maintenance was being performed at the school.Lack of recollection 'too convenient'The board rejected the idea that D'Angelo had no recollection of the assault. It said it was "too convenient" that he remembered almost everything else that night, but had a blackout during the critical part. It cited a case involving Air Canada in which an arbitrator cautioned against accepting a worker's explanation that he was in an "alcoholic blackout" at the time of his misconduct:"Given the ready convenience of this kind of 'blackout' defence, one has to be circumspect in simply taking the transgressing employee's word for it," the arbitrator said in the Air Canada case. "It is significant to have other independent evidence that would provide corroboration of the employee's capacity at the time in question."The board said there was some evidence D'Angelo did remember the assault — his wife testified that when he came home, he told her that he had spoken with the victim privately that evening to tell her what a good job she had been doing, and that he had given her a hug and a kiss.The board was also critical of D'Angelo for not offering an apology to the victim. While he did apologize to her for the possible use of foul language on the night in question, he did not offer an apology for the assault. D'Angelo said that was because he didn't remember the assault, something the board had already discounted."In our view, an apology was due for his drunken assault on her immediately (after) he sobered up," the board said. "His apology to her on Feb. 5 cannot be regarded as a true apology since, even according to his evidence, it only related to the question of the possible use of bad language."It attached no weight to an apology conveyed by union counsel on D'Angelo's behalf to a staff review panel because it was not addressed to the victim and was sent more than a month after the assault and after he had been suspended.A serious act of misconduct, fuelled by alcoholThe board said it accepted the fact D'Angelo had a lot to drink during the afternoon and evening of Feb. 3, and that his behaviour that night was influenced by the alcohol and possibly aggravated by the prescription medication.It said the assault was "quite out of character" for D'Angelo. It said several arbitration decisions have examined how a worker's intoxication at the time of serious misconduct should be taken into account by arbitrators."Unlike the situations in many of those awards, there is no suggestion here that (D'Angelo) was suffering from alcoholism," the board said. "There is also no room for doubt here about a causal relationship between the drinking and the misconduct."But the fact he was drunk did not distract at all from the seriousness of the misconduct, it said."Employees at work are entitled to be protected from sexual assaults," the board said. "It is obviously unacceptable that an employee, even drunk, returns to his workplace after hours, lets himself into the building with his own keys, and assaults one of his subordinates."Why the board ordered reinstatementThe board said its decision should not be taken as minimizing the seriousness of the behavior. So why, then, did the board order his reinstatement?The board said it was satisfied that intoxication giving rise to serious misconduct should be viewed as a mitigating factor. In the earlier mentioned Air Canada decision, the arbitrator reduced the penalty of an employee from a discharge to a lengthy suspension after he had stolen company property during a alcoholic blackout. After reviewing expert evidence on alcoholism and blackouts and various earlier awards, the arbitrator in the RELATED ARTICLES$611 million in Sears Canada dividend payments under review by court monitorBritish gay man wins right to equal pension for husband in landmark decisionOne employment relationship saved, another destroyedAir Canada case concluded:"I am satisfied that the condition and behaviour of the grievor at his workplace on April 15 was in fact an aberration, wholly uncharacteristic of the grievor as an employee, and a direct result of the unusual circumstances of that day that led him to drink excessively before his shift. The grievor appreciates that intoxication at work can never be a complete justification, and claims no back pay in the matter. He has been off work from Air Canada for almost three years — eight months without income, and since then at a lesser rate (as well as benefit package.) That, I am satisfied, constitutes an appropriate penalty … as opposed to discharge."In D'Angelo's case, the board said it was worth nothing that, unlike in Air Canada, he did not show up to work intoxicated."He returned to the workplace intoxicated after the end of his shift, at a time when it was not unreasonable for him to be drinking, as he was not due to work for another 10 hours or so," the board said. "In our view, this element adds greater strengths to the mitigating factor."It summed up the case as follows:•a worker with 16 years of unblemished service;•a single episode of very serious misconduct;•no apology; and•D'Angelo's intoxication at the time, when he was not due to be at work for another 10 hours.It said discharge in this case simply wasn't warranted. It said there was no basis to conclude that the school board could not trust D'Angelo to behave appropriately in the future, but it did emphasize that it was troubled by the lack of apology."We accept that denunciation, protection of other staff and deterrence are legitimate objectives of discipline in a case like this, but we feel that a lengthy suspension can accomplish those goals," the board said.But it also said it would be "unacceptable" for D'Angelo to go back to a position where he would be supervising or working with the victim."She is the innocent party in this matter and should not be forced with daily reminders of her terrifying experience," the board said.Therefore it:•set aside the discharge;•said D'Angelo was to be considered a surplus employee, entitled to recall, except that he is not entitled to bump any other employee and will not be assigned to the school where the victim is working; and•ordered that D'Angelo was not entitled to any compensation for lost earnings.For more information see:• Ottawa-Carleton District School Board v. O.S.S.T.F., 2005 CarswellOnt 5056, [2005] L.V.I. 3592-2 (Ont. Arb. Bd.)• I.A.M.A.W., Local 2323 v. Air Canada, 2000 CarswellNat 1300, [2000] L.V.I. 3113-6, (sub nom. Air Canada v. I.A.M., Loc. 2323) 89 L.A.C. (4th) 97 (Can. Arb. Bd.)© Copyright Canadian HR Reporter, HAB Press. All rights reserved. Add Comment * Title * Name * Email Anonymous * Comment


text:
The aim of the project is to investigate nuclear matter at high temperatures and pressure using the CHPC for large-scale calculations, hydrodynamic modelling simulations and data analysis. The specific case of simulation and analysis of high energy nuclear physics data has been selected due to the experience of the three groups involved in performing this work, the UCT-CERN Research Centre (University of Cape Town), and iThemba LABS, as well as the suitability of this field of science for the investigation of high-energy physics. The consortium will also assist the CHPC in promoting the development of GRID in South Africa by implementing GRID computing workshops. They will furthermore promote the usage of GRIDS in all other scientific disciplines.
Last Updated on Tuesday, 24 July 2012 18:06
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Quantum information technology has gained tremendous momentum in the research arena over the past decade and its potential impact on the future was realised in South Africa when the Quantum Research Group at UKZN received a substantial amount of funding from the Innovation Fund to set up a Centre for Quantum Technologies and to develop a quantum key distribution system. One of the ultimate goals of quantum technology is to produce a completely self-sustained quantum computer. Quantum computers based on logic quantum gates are able to perform certain computational tasks more efficiently than classical computers. However, there are still technological shortcomings with respect to the realisation of quantum gates, the building blocks of the quantum computer.
One of the novel and most promising candidates in realising quantum gates are double-optical lattices, periodic atom structures created by atom-photon interactions. The double-optical lattice structure was first implemented by Prof A. Kastberg and his research team (Umea, Sweden). The Quantum Research Group at UKZN is involved in collaborations with this research team and much progress has been made in the development of a quantum model that can be used to simulate quantum state manipulation of atoms or de-coherence in this lattice structure. It is vital to be able to simulate the dynamics of the atoms in the construction of these quantum gates. The numerical simulation of this model is based on Monte Carlo Wave Function techniques, renowned as an efficient numerical tool, for their and requires the diagonalization of matrices of 10 000 x 10 000 for a complete description of the dynamics. With these techniques and ensemble of stochastic state vectors are propagated in the open system's space so that the reduced-density matrix is recovered through an appropriate ensemble average. Unravellings of time-local non-Markovian quantum master equations in a doubled Hilbert space obtained by time-convolutionless projection operator technique allow for efficient Monte Carlo algorithms.
A generalisation of the Lindblad theory on the regime of highly non-Markovian quantum process in structured environments has been developed by H.P. Breuer, with whom the UKZN Quantum Research Group collaborates in research efforts. This research intends to investigate realistic quantum optical and spintronic devices that exhibit non-Markovian behaviour by using recently-developed algorithms. Exact Monte Carlo methods have been developed for the representation of the non-Markovian dynamics of open quantum systems. These techniques lead to an exact solution of the Von Neumann equation of the total system and they have been shown to be successful in studies of simple-spin models for de-coherence.
Last Updated on Tuesday, 24 July 2012 18:04
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RNA viruses, such as HIV, have extremely high mutation rates largely attributable to a low fidelity reverse transcriptase. This high mutation rate of HIV combined with a large effective population size and a short generation time, result in an enormous capacity to generate diversity and to adapt to changes in the host environment. This has important implications for the design and monitoring of drug treatment regimens and is the primary reason for the difficulty experienced in developing a HIV vaccine that is effective across the globe. Moreover, the intra-host evolution of the virus is an essential part of the HIV disease dynamics. It is therefore vital to develop tools to understand HIV evolution within and across infected individuals. HIV data collection efforts are on the increase in scale and resolution as a result of ultra-high throughput sequencing technology and the large-scale application of the Single Genome Amplification (SGA) technique. Efforts to monitor the large-scale roll-out of antiretroviral treatment in South Africa will generate large quantities of molecular sequence data. The availability of data as well as the biologically and clinically relevant insights that can be obtained by modelling intra-host evolution, emphasize the need to develop and apply more accurate and biologically-relevant evolutionary models.
Probabilistic models of sequence evolution typically assume a continuous-time Markov process whereby a rate matrix Q with elements qij denoting the instantaneous DNA substitution rates from codon i to codon j. This enables the determination of a transition probability matrix P(t), as a function of time, that describes the probability of a substitution from state i to state j in a time interval t. Typically, sequences are modelled along the branches of a phylogenetic tree which may be known already or may be included as one of the parameters to be estimated. In one approach the likelihood of a codon alignment, given an estimated phylogenetic tree of relationships, is calculated using a model of evolution that constrains all DNA sites to evolve naturally and then compares it to the likelihood using a model in which a subset of sites are permitted to evolve adaptively. Positive selection is inferred when the latter model is favoured (using standard model comparison techniques).
The distinction between neutral and adaptive evolution is captured by comparing the relative rates of substitutions that alter the encoded amino acid (referred to as non-synonymous substitutions) and substitutions that, because of the degeneracy of the genetic code, have no effect on the encoded amino acid sequence (referred to as synonymous substitutions). The latter class results in the substitution of one codon (or nucleotide triplet, encoding an amino acid) for another codon that encodes the same amino acid, often assumed not to have any effect on organism fitness, and therefore to occur at the neutral rate of evolution (which, according to evolutionary theory, is the same as the rate of mutation). When coding sequences evolve such that the rate of non-synonymous substitution (dN) is greater than the rate of synonymous substitution (dS), positive Darwinian selection (i.e. adaptive evolution) can be inferred. The inference of positive selection and the sites that are evolving under selection can reveal key aspects of organism biology – particularly in the context of pathogen infection and host resistance.
Strategies as the one discussed supra have been used to investigate the evolution of resistance to drug treatment in pathogens, including HIV-1, and have also been used to study escape from immune responses. The models proposed in this study are modifications of these general models of sequence evolution and will be designed to provide more power to detect the effects of immune responses on HIV evolution intra-host, and to detect more sensitively the footprint of host immune genotype on the virus. The study proposes to extend directional selection models, in the context of antiretroviral drug treatment, the detection of secondary resistance mutations and apply these models to sequence data sets from southern Africa and to sequence data sets that are available to the public.
The descriptive project objectives are:
Each of the objectives stated above will be addressed through the development of custom probabilistic models of evolution implemented in HyPhy, the R-package or C/C++.
Develop and apply methods to evaluate the intra-host evolutionary selective pressure acting on HIV-1 protein-coding genes
Previous models of sequence evolution give very high rates of false positives when applied to recombining sequences such as HIV. A model was recently developed to alleviate the confounding effects of recombination on parameter estimation. As part of another study, the researchers intend to carry out an exhaustive survey of selective pressures in HIV protein-coding genes using this model with a view to re-evaluating the published evidence of selection and its biological significance using an unbiased method. The intention is to distinguish between evolutionary selective pressures acting on viruses within individual hosts and selective pressures that shape the evolution of the pandemic more generally. In the first case, the researchers will focus on selective pressures acting on the virus in acute infection. This critical stage of the disease is believed to have a significant impact on set-point viral load, which in turn affects the rate of disease progression. Understanding the nature of the virus isolated from acute infection and its adaptation to the new host environment has potential implications for vaccine development.
The PI of this research is an investigator on the CHAVI project (http://www.chavi.org/) through which he has access to a large set of highly accurate sequences from the HIV env gene, generated through the Single Genome Amplification technique from samples collected in North America (approximately 3 400 unpublished complete sub-type B coding sequences generated from samples from 102 acute individuals). A large number of env coding sequences isolated from southern African individuals acutely infected with HIV sub-type C became available in 2008. These data form a very comprehensive data set and give rise to a unique opportunity to understand the nature of the virus that is transmitted to newly-infected individuals (a key objective of the CHAVI project) as well as the nature of the selective forces that shape the evolution of the virus in the crucial phase of infection (the primary objective of this study). The CHAVI project will also generate whole genome HIV sequences at later stages, and this will enable investigation of the evolution of other HIV genes.
With input from other researchers, the research team has implemented a method to assess the selective pressure acting on HIV sequences in acute infection, using the HyPhy batch language for evolutionary modelling. The method combines evidence over multiple phylogenetic trees representing the evolutionary relationships of sequences from different infected individuals. For each infected individual, the time to the most recent ancestor of the sequences in the individual is estimated using Bayesian Evolutionary Analysis Sampling Trees (BEAST). This method makes use of the Markov Chain Monte Carlo (MCMC) algorithm to sample polygenetic trees (the graphs representing the relationships between the viral sequences) according to their posterior probabilities, given the sequence data. Given a set of sampled trees and a set of input parameters, including mutation rate and generation time, confidence intervals on demographic parameters of interest can be inferred, including the time to the most recent common ancestor of the viral sequences. If the most recent common ancestor of the sequences post-dates the estimated time since the patient was infected (based on clinical stage information), we can be confident that the observed viral diversity was generated during acute infection. The MCMC algorithm used by BEAST is naturally parallelisable since a single chain from which posterior distributions are derived can be sub-divided across multiple nodes. This research team has developed an automated MPI wrapper for BEAST and has tested scalability on an acute infection data set derived from the CHAVI project and because MCMC methods are well-suited to parallel implementation we expect good parallelisability.
This research team will use the methodologies set out above to determine whether the HIV env gene evolves under positive Darwinian selective pressure in acute infection and, if so, identify the sites in HIV env that evolve rapidly at this stage. The researchers expect that these sites will include reversion of mutations that enabled the virus to escape from immune responses that were present in the infecting individual, but absent from the newly-infected host and possibly mutations that facilitate escape from the earliest antibody responses of the newly-infected host. CHAVI investigators have revealed a severe population bottleneck in HIV transmission to the extent that most new infections result from expansion of just a single viral particle, and there is great interest in determining whether this bottleneck is selective (Does the process of HIV transmission from one host to another select for a viral strain that is particularly adapted for this purpose?). This concept is topical, because if transmission involves a severe selective bottleneck, vaccines need not target the full diversity of HIV, but merely a sub-set of strains selected for improved inter-host transmission. If the bottleneck is selective, consistent reversion of amino acids that are advantageous fro transmission to a state that is most advantageous for expansion in a newly-infected host, will leave a detectable signature of positive selection.
Develop a method to model viral evolution and host genotype simultaneously and to use this model to identify the footprint of the host genotype on the autologous viral sequence
One of the most exciting developments in genomics recently has been the development and broad application of whole genome genotyping technologies. These technologies enable genotypes of up to a million single nucleotide polymorphisms (SNPs) to be determined in a single experiment. One of the objectives of this research is to develop the capacity to model the genome sequence of a pathogen and its host simultaneously. HIV is known to evolve under extremely strong evolutionary selective pressure. This fact is central to the current research and an essential aspect of the pathogenesis of the virus. The main driving force for the very rapid and adaptive evolution of HIV is the host environment. The dynamics of the adaptive immune response within individual hosts drives adaptive evolution of HIV within the host.
Differences in the innate and adaptive immune capacity between hosts as well as differences between hosts in a large number of non-immune-related host proteins with which the virus must interact, drive adaptive evolution between the hosts. There have been several attempts to determine the footprint of the host immune capacity on HIV sequences, but no attempt has been made to determine the more general footprint of host genotype on viral sequence evolution. Collaborators in the CHAVI project carried out the first large-scale whole-genome association study of human loci that affect HIV disease progression. This project proposes to use the data from the whole genome association study, together with HIV sequence data from the same individuals that were genotyped as part of that study to investigate general host factors that place a selective pressure on HIV and thereby to establish the general host molecular footprint on the virus. This has profound implications for understanding the mechanisms through which different hosts progress to disease at very different rates and for understanding the biology of HIV pathogenesis. Determining the footprint of the host genotype on HIV sequence requires simultaneous models of sequence evolution and the host environment. Previous studies that investigated the footprint of HLA alleles on an HIV sequence have generally either neglected to account for the non-independence of epidemiologically-linked data or have use heuristic methods to take this into account.
This research proposes to take a more complete model approach to the problem of finding a relationship between viral sequence polymorphisms and host HLA genotype. This model will explicitly model the host genotype and allow sequence evolution to depend on the HLA allele. The method in this research will sum over the genotypes of individuals infected by the ancestral viral sequences, represented by the internal nodes of the tree since these genotypes are unknown. It is possible to encode this analysis using the HyPhy batch language; however, the analysis is extremely computationally intensive owing to the addition of a variable (HLA allele) over which all ancestral nodes of the tree have to be summed. This approach furthermore requires the researchers to test for relationships by fitting models independently for each pair consisting of an amino acid site and an HLA allele. Approximately 20 HLA alleles are readily found in southern African populations to enable testing with this method. The HIV genome is approximately 10 000 base pairs long and approximately one third as many amino acids will be encoded. The implementation of this project thus requires the optimization of 20 x 3000 models. A reduction in computational requirements will be obtained by removing invariant and slow-moving sites, although the computational requirements of this part of the project remain significant. This task is highly parallelizable since there is independent model-fitting for each pair of amino acid site and HLA allele.
Model viral evasion of host immune responses, in particular T-lymphocyte (CTL) responses
Escape from host immune responses can be associated with a significant cost in terms of viral fitness. Reversion of escape mutations to wild-type in hosts lacking a specific immune response and re-escape in hosts with the response can cause a pattern of amino acid toggling. Sequences tend to toggle between a very fit state and an easily accessible or very unfit escape variant. This research proposes to develop a model of amino acid toggling to improve the sensitivity with which it is possible to detect evasion of immune responses that carry high costs in terms of viral fitness. Positive Darwinian selection can be inferred when the rate of non-synonymous, dN, (amino-acid changing) substitution is greater than the rate of synonymous, dS, substitutions. Although dN.dS is sufficient to infer positive Darwinian selection, it is not necessary. The objective in this research is to develop methods to infer positive Darwinian selection from coding sequences when dN=dS. In the case of selective pressure for escape from a specific CTL response and reversion to the most fit amino acid in individuals lacking the CTL response, the researchers expect to observe toggling between the most replicative fit, but immune susceptible state and toggling between the least fit, but immune escaped state. If the rate at which mutations between these states occur are greater than the rate predicted under random neutral mutation, positive Darwinian selection can be inferred, even when dN
Validation of the models of sequence evolution proposed requires extensive simulation with significant high-performance computing implications. In order to determine whether these models are applicable to real-world HIV and other comparable sequence data sets, the researchers will simulate data sets using parameter values and sizes comparable to published data sets of HIV genes that have been used to carry out relatively heuristic investigations of the relationship between immune system alleles (in particular alleles of the Human Leukocyte Antigen – HLA) and sequence evolution. HyPhy allows simulation of data sets using flexible input models and will also be used to fit the models of the simulated data. Fitting the evolutionary models to data involves calculating the likelihood of a data set given a phylogenetic tree (byfurcating tree structure representing the relationships between the sequences, with the lengths of the tree branches representing evolutionary distance), a model and a set of parameter values. The ancestral states of the sequence (the states of the sequence at the ancestral or extinct nodes of the tree) are unknown, and therefore the data of the tree is calculated as a sum over all possible ancestral states. The number of ancestral nodes are more or less equal to the number of sequences (which can be a few hundred) and the alphabet size for codon models of evolution is relatively large, making it computationally intricate to calculate. It can however be calculated in a reasonable time using the dynamic Felsenstein's Pruning programming algorithm. Fitting the model to the data involves optimization and the EM algorithm will be applied, but this makes for difficulty in parallelisation. The number of simulations carried out will depend on the availability of computer resources, but ideally this research would like to simulate 1 000 replicate data sets fro each model tested in order to reduce the variance in the false positive and power estimates.
Evolutionary modelling to confirm putative CTL (and, later, antibody) epitopes
As an extension of the model proposed above, the research team will investigate the development of a model specifically designed to aid in the identification of epitopes (the regions with pathogen proteins that are recognised by the host immune system). The researchers will firstly concentrate on epitomes recognised by human cytotoxic T-lymphocytes (CTLs) since these epitopes are contiguous on the viral sequence. The PI of this research has worked with researchers at the South African National Institute of Communicable Diseases (NCID) where they have experimentally identified the approximate regions within HIV proteins recognised by the CTL response (using interferon-gamma ELISPOT assay). They have also generated HLA genotype data for these HIV-infected individuals. This type of data has also been generated in laboratories in other parts of the world.
HLA proteins function in presenting the epitope at the cell surface, where it interacts with receptors on immune cells, causing a CTL-mediated immune response. It is possible to hypothesise that the CTL response to a given peptide is mediated by a given HLA allele when the HLA allele is statically over-represented among individuals indicating a specific CTL response. The researchers propose to confirm the existence of a relationship between specific HLA alleles and CTL-recognised peptides through the use of evolutionary modelling. In particular, the research will model the evolution of a CTL-recognised peptide, allowing different evolutionary rates along branches leading to individuals with and without a focal HLA allele. For branches of the phylogeny leading to ancestral nodes (where the HLA state is unknown because the individual infected by the ancestral virus is not present in the data set), a mixture model will be used with mixture proportions equal to the frequency (and one minus the frequency) of the HLA allele. This will enable the researchers to determine whether the evolutionary rate within a specific peptide is dependent on the presence or absence in an infected individual of the HLA allele under investigation. This approach can easily be extended by developing directional models of selection analogous to the model used to investigate drug resistance. In this instance the researchers will test whether there is a tendency at specific sites within the peptide to mutate away from the wild-type (or default state) in the presence of the HLA allele and towards the wild-type in its absence. This would provide a signature of immune escape and enable the researchers to pinpoint mutations that enable the virus to evade the immune response, while it would also provide strong evidence for an epitope for the investigated HLA allele within the peptide region modelled. The researchers have not determined parallelisability. Since it is similar in concept to the modelling of the human genotype-HIV evolution, it is likely to require substantial computational resources. The researchers predict that the project will scale more or less linearly with the number of epitope-HLA allele combinations.
Detect compensatory mutations associated with the evolution of anti-retroviral drug resistance
The recently-developed models of the evolution of drug resistance will be extended to the detection of compensatory mutations and this model will be applied to the serially sampled HIV sequences. These models will be used to detect compensatory mutations associated with the evolution of resistance to anti-retroviral drugs using the data set of Nevirapine-treated individuals that formed the basis for a recent study and from the new drug treatment data sets as they become available from the National Institute of Communicable Disease. The proposed method will test for dependence between evolutionary rate at a candidate accessory resistance site and the resistance state at known resistance sites. This will require independent model fits and optimizations for each site and for each of the most important known drug resistance sites. This task is computationally highly intensive, but also highly parallelisable and the researchers expect linear gains in efficiency with the number of available computer nodes.
Each of the five objectives described above requires substantial computing resources: in obtaining sufficiently large numbers of samples for accurate estimation using MCMC sampling techniques, for analysis of multiple databases, and for extensive testing of custom models through simulations. Preliminary analyses using some of the models were computationally extremely intensive (approximately two hours per codon site). Since these models are subdivided by codon site, they can be parallelised relatively easily.
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Last Updated on Tuesday, 24 July 2012 18:36
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Cosmologists seek to understand the structure and evolution of the universe and its physical constituents. A field that lies at the interface of astronomy and particle physics, cosmology has undergone a major revolution over the past decade, made possible by a wealth of observational data from cutting-edge experiments and telescopes. The wide range of these cosmological observations is impressively fit by a simple concordance model with a small number of parameters.
Modern South African Astronomy and Cosmology: Confronting the Simulated and the Observed Universe
The standard cosmological model describes an expanding universe that is smooth on the largest scales with inhomogenous structures, such as galaxies, galaxy clusters and super-clusters, present on smaller scales. These structures originated from small fluctuations, or irregularities, that were present in the matter distribution in earlier times and which then steadily grew via gravitational instability to form the variety of observed structures. In addition to the familiar, visible matter there is strong evidence that the universe contains significant fractions of dark matter and dark energy that dominate the cosmic energy budget today.
Despite the remarkable success the cosmological model has enjoyed, there are several outstanding issues that remain. The leading challenges in cosmology are:
Major national and international astronomical facilities will help address these questions and further transform our understanding of the cosmos. All three investigators on this research will play a leading role in cosmological surveys on those facilities. The researchers at UKZN, UWC, UCT and NASSP will be involved in a large telescopic survey of supernovae and galaxy clusters on the Southern African Large Telescope. This data will be used in conjunction with photometric data from the Sloan Digital Sky survey (SDSS) and microwave data from the Atacama cosmology Telescope (ACT) to study the use of supernovae and galaxy clusters, respectively, as probes of the dark energy. Both the SDSS and the ACT projects are high-profile international projects, of which the researchers are members. The microwave data from ACT can be combined with Wilkinson Microwave Anisotropy Probe (WMAP) data and future polarization data to set strong constraints on the nature of the primordial fluctuations. The South African MeerKAT radio telescope project will map out the distribution of neutral hydrogen (cold gas) in galaxies at intermediate redshift. The cold gas plays a pivotal role in galaxy and cluster evolution.
With the wealth of incoming data, cosmology has now entered the high-precision era. To analyse and interpret this data and to use it to constrain theoretical models requires significant computational effort. Large cosmological N-body simulations are necessary to understand the distribution of large-scale structures and the complicated gas physics that influence how galaxies and galaxy clusters evolve. These simulations are also used as an impetus to understand the yield of astronomical targets (supernovae, galaxy clusters) in large cosmological surveys in different wave bands. Computationally intensive algorithms that maximise the constraints on dark energy from large supernovae surveys are necessary to design optimal surveys. The N-body and hydrodynamic simulations are also used to study the systematic effects that arise in large observational surveys, and to calibrate these effects when studying real data – issues that will be studied for microwave observations. Large Monte Carlo Markov Chain simulations are necessary to estimate cosmological parameters from the variety of data sets resulting from these observational surveys, thereby further refining the cosmological model. The CHPC provides an unprecedented opportunity to complete this computationally intensive programme that will help to address leading cosmological questions.
Last Updated on Tuesday, 24 July 2012 18:01
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This project addresses electromagnetic computer simulation of key elements of the proposed Square Kilometre Array (SKA).
Electromagnetic Computer Simulation for the MeerKAT and SKA
The world's radio astronomy community is working together to conceptualise the SKA - the largest and most sensitive radio telescope ever. It is likely to consist of a myriad of dishes, each 10-15m in diameter. Special antenna tiles in the core of the array will form a "radio fish eye lens" for all sky monitoring at low frequencies. This will allow many independent simultaneous observations. The joint receiving area of all these dishes and panels will add up to approximately one million square metres. The SKA will require super-fast data transport networks ever-increasing powerful computing. South Africa and Australia are the only two countries on the short-list to site this mega-telescope. A final decision on the site is expected by 2010 and construction should start in 2014. Should the telescope be sited in South Africa, the SKA's core will be in the Northern Cape Province (in the Karoo region). The SKA will consist of thousands of antennae spread over several thousands of kilometres. Approximately half of the antennae will be concentrated in a central region of approximately 5km in diameter.
The SKA is an international mega-science project and the projected cost is currently one billion euros. The erection of the SKA in South Africa will serve as a catalyst to firmly connect South Africa with international science.
The MeerKAT, another very important South African project with a budgeted cost of R800 million, is considered the largest government-funded science project since the early 1990s. The MeerKAT, with its approximately 80 dishes, is intended to serve as a technology demonstrator for the SKA, but will also be used independently.
The primary elements in both the SKA and KAT are receiving antennae. Due to the large size and complex design of these structures with demanding specifications, CEM plays a key role in the optimal design of the elements of the antennae to ensure maximum scientific return on investment.
A primary application of the SKA is the mapping of the entire sky and the ability to observe several parts of the sky simultaneously (in theory, as many times as there are elements in the focal plane array) can substantially reduce survey time (which can be measured in years for some radio astronomy projects). The focal plane array (located in the feed point) places a number of receiving elements at the focus of the main dish (probably a reflector with a 12 m diameter) and allows for the effective reception of a number of beams simultaneously. Simulating even a small array over the operating band of KAT requires high-performance computing. A major challenge in the construction of these antennae is to create them to be able to operate effectively across a wide frequency range. Constructing large arrays are grand challenges and thus call for the use of high-performance computing.
Last Updated on Tuesday, 24 July 2012 18:08
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text:
Ryan Mayer
I want to take a minute before we get to the picks for this week to appreciate just how ridiculous Steelers' wide receiver Antonio Brown's last two weeks have been. Brown has caught 20 passes for 313 yards and five touchdowns. That account for a full 48 percent of Roethlisberger's 650 passing yards, nearly a third of his completions (63) and a full 62.5 percent of his touchdowns (8) in that span. The Big Ben to Brown connection has led to monstrous games for the Steelers offense and it has been beautiful to watch. Especially when Brown is making catches like this.
In a year in which so many exciting players have gone down to injuries, watching Antonio's masterful displays of his craft is one of the few joys left on Sundays.
No way we can lose – locks of the week: As you can guess, these will be the stone-cold locks of the week. The games I'm so confident about that I'd wager my life's savings on them, if I had a life's savings to wager.
Feeling pretty… pretty good: Not quite willing to bet the farm on this batch, but as Mr. Larry David would say, 'I'm feeling pretty… pretty good' about these games.
Heads or tails: These are your true toss ups: they can go one way or another, and you should pick with caution, even after heeding my expert advice.
All lines courtesy of Sportsline. All times Eastern.
Washington Redskins @ Dallas Cowboys (-1.5), Thursday 8:25 p.m.
Level of Confidence: Feeling Pretty…Pretty Good
ATS & Straight up: Redskins
Nothing I've seen from Dallas and Dak Prescott in the past two weeks inspires any confidence in their ability to beat anyone. Let alone a division foe who is raring for revenge. Kirk Cousins and the 'Skins are fighting for the playoffs and I think they get a step closer here.
No Way We Can Lose…Locks of the Week
New England Patriots @ Buffalo Bills (+8), Sunday 1:00 p.m.
ATS & Straight up: Patriots
The Patriots have turned into their usual December killing machine. Buffalo found success slowing down the Chiefs last weekend, but the Patriots with a red-hot Tom Brady are an entirely different animal.
Minnesota Vikings @ Atlanta Falcons (-3), Sunday 1:00 p.m.
ATS & Straight up: Vikings
The Falcons have started to find their stride on offense, in particular, wide receiver Julio Jones. Jones went off for 12 catches, 253 yards and a pair of touchdowns last week, but that came against the Buccaneers defense. This Vikings unit is one of the best in the league at shutting down opponents' passing games (11th in NFL) and they get after the QB (30 sacks, t-9th). Minnesota gets the win on the road.
Cleveland Browns @ Los Angeles Chargers (-13), Sunday 4:05 p.m.
ATS & Straight up: Chargers
The Chargers have gotten hot at the right time. The Chiefs are struggling, the Raiders have their own issues and the Broncos are, well, likely out of the AFC West race. That means Los Angeles, which started the season 0-4, is right in the thick of things at 5-6 on the year. The main reasons for that are a dominant pass rush and Phillip Rivers. The Browns, after some promising play at the beginning of the year, have tailed off to their normal level of terribleness. L-A gets the big win to get back to .500.
Feeling Pretty…Pretty Good
Detroit Lions @ Baltimore Ravens (-3), Sunday 1:00 p.m.
ATS & Straight up: Ravens
Flacco and the offense haven't been good, but the defense is legit. The Lions offense can be explosive, but the defense has been terrible since losing Haloti Ngata earlier this season. Alex Collins finds some success on the ground and the Ravens win.
Indianapolis Colts @ Jacksonville Jaguars (-9.5), Sunday 1:00 p.m.
ATS: Colts
Straight up: Jaguars
I'm hesitant to take the Jaguars in any games featuring big lines solely because of Blake Bortles. I don't trust him to not turn the ball over. The Colts are bad, but Jacoby Brissett has been able to keep them in most games. They cover here, with Jacksonville pulling it out.
Kansas City Chiefs @ New York Jets (+3.5), Sunday 1:00 p.m.
ATS & Straight up: Jets
The Chiefs have fallen apart. They're 1-5 in their last six games after a 5-0 start to the season. The offense looks stagnant and Alex Smith has reverted back to his normal checkdown self, not pushing the ball down the field the way he was at the beginning of the season. The Jets have also lost five of six games, but they've been within one possession in each of those losses. They get over the hump here and beat a struggling Chiefs team.
Philadelphia Eagles @ Seattle Seahawks (+4), Sunday 8:30 p.m.
ATS: Seahawks
Straight up: Eagles
This is a tough one. The Seahawks always play well in front of their home fans and Russell Wilson has been an absolute magician this year. Seattle also shut down the Eagles last year, winning 26-15 in front of the CenturyLink crowd. But, the Seahawks defense is banged up, and the Eagles front four could present big problems against a bad Seattle offensive line. This will be a good barometer for just how good the Eagles are, and they squeak by with a win.
Pittsburgh Steelers @ Cincinnati Bengals (+5.5), Monday 8:30 p.m.
ATS & Straight up: Steelers
Pittsburgh is rolling, and Ben Roethlisberger is finally looking like his old self. As mentioned at the top of the post, Antonio Brown has a large part in that with 20 receptions for 313 yards and five touchdowns in the last two weeks. That's insane. While that production has to tail off a little at some point, the Steelers have enough weapons to beat their AFC North rivals on Monday night.
Heads or Tails…Toss Up
Denver Broncos @ Miami Dolphins (+1), Sunday 1:00 p.m.
ATS & Straight up: Broncos
I refuse to pick the Dolphins anymore. I'm done. Picked them to cover 16.5 points last week. They lost by 18. Nope, not gonna do it again. Now, watch, they'll somehow end up winning this game.
Houston Texans @ Tennessee Titans (-7), Sunday 1:00 p.m.
ATS: Texans
Straight up: Titans
The Titans have been playing with fire in recent weeks, playing close games against bad teams. They beat the Colts by just four and beat the Bengals, Ravens and Browns by just three. I have zero reason to expect that they'll beat the Texans by a touchdown. All available evidence says otherwise.
Tampa Bay Buccaneers @ Green Bay Packers (0), Sunday 1:00 p.m.
ATS & Straight up: Packers
Brett Hundley and the Packers offense didn't play terribly against the Steelers on Sunday night. He'll have a much easier task against a bad Buccaneers defense this week.
San Francisco 49ers @ Chicago Bears (-4), Sunday 1:00 p.m.
ATS: 49ers
Straight up: Bears
The 49ers will start Jimmy Garoppolo for the first time since acquiring him this week. Garoppolo did complete both passes he attempted last week and threw his first touchdown pass as a member of the Niners, but this is the first time we'll get to see him play a full game. It's a bit of a soft landing for him as the Bears defense has begun to struggle in recent weeks after being hit by injuries. San Fran keeps this one close, but the Bears running game eventually puts the game away.
Carolina Panthers @ New Orleans Saints (-4), Sunday 4:25 p.m.
ATS & Straight up: Panthers
New Orleans won the first meeting between these two teams back in September and the Panthers looked awful in that game. Cam Newton in particular, played poorly going 17/26 for 167 yards and three interceptions. It's been an up-and-down season for Newton, but he and the Panthers have started to get on a roll winning four straight since an ugly loss to the Bears on October 22nd. The Panthers defense makes a couple of big plays and so does Cam as Carolina takes over the top spot in the NFC South.
Los Angeles Rams @ Arizona Cardinals (+7), Sunday 4:25 p.m.
ATS & Straight up: Rams
The Cardinals surprised a lot of people by getting the win over the Jaguars last week, myself included. But, this week, they're playing a much better Rams team that got back on track with a big win over the Saints last Sunday. Rams get the win.
New York Giants @ Oakland Raiders (-7.5), Sunday 4:25 p.m.
ATS & Straight up: Raiders
The Giants just benched Eli Manning because head coach Ben McAdoo needs to "see more" of Geno Smith and what he can do. Ask any Jets fan, they'll be able to tell you. The Raiders offense is banged up, but they should be able to get the win.
Last Week
Straight: 13-3
Straight: 113-62