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SBDC at Kean University Presents Becoming A Successful Consultant
UNION, N.J. - The Small Business Development Center of Kean University will present a free seminar, entitled, Becoming A Successful Consultant, on Tuesday, March 30, from 6 p.m. to 8 p.m. in the Scotch Plains Public Library, located at 1927 Bartle Avenue in Scotch Plains, N.J.
Herb Caesar, president of CED Solutions, LLC, in Englewood, N.J., will discuss a host of topics related to becoming a successful business consultant, including the IRS guidelines of the consultant vs. contract employee, defining a field of expertise with appropriate credentials, identifying and marketing skills that provide added value to clients, project/client management and juggling schedules. He will also cover establishing and negotiating compensation, assessing emotional support from personal household/spouse, defining valuable relationships and collaborative alliances, establishing target market/niche and perception of one's practice within the industry and management and personnel functional structure and development.
Special arrangements for people with disabilities can be made upon request. Be sure to bring business cards and brochures for networking purposes. For further information or to register, please contact Mira Kostak at 908-737-4220.


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Photos from day two of the US Open
. The cut looms for the 156 golfers at the US Open. Follow along with our live scoreboard to see if your favorite survives and check back here for more photos from the afternoon session which will feature Bubba, Phil and Tiger. [Read More]

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The National Organization for Rare Disorders (NORD) web site, its databases, and the contents thereof are copyrighted by NORD. No part of the NORD web site, databases, or the contents may be copied in any way, including but not limited to the following: electronically downloading, storing in a retrieval system, or redistributing for any commercial purposes without the express written permission of NORD. Permission is hereby granted to print one hard copy of the information on an individual disease for your personal use, provided that such content is in no way modified, and the credit for the source (NORD) and NORD's copyright notice are included on the printed copy. Any other electronic reproduction or other printed versions is strictly prohibited.
The information in NORD's Rare Disease Database is for educational purposes only. It should never be used for diagnostic or treatment purposes. If you have questions regarding a medical condition, always seek the advice of your physician or other qualified health professional. NORD's reports provide a brief overview of rare diseases. For more specific information, we encourage you to contact your personal physician or the agencies listed as "Resources" on this report.
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Niemann-Pick disease (NPD) is a group of rare inherited disorders of fat metabolism. At least five types of Niemann-Pick disease have been identified (NPD types A, B, C, D, and E). Symptoms of types A and B occur as a result of a deficiency of the enzyme acid sphingomyelinase (ASM), which is needed to break down sphingomyelin, a fatty substance found mostly in the brain and nervous system. This deficiency results in abnormal accumulation of excessive amounts of sphingomyelin in many organs of the body such as the liver, spleen, and brain. Symptoms of type C occur because of impaired trafficking of large molecules within cells, which results in the accumulation of excessive amounts of cholesterol and other lipids (glycosphingolipids) tissues throughout the body. The metabolic defect in type C can lead to a secondary reduction in ASM activity in some cells.
The division of Niemann Pick disease into groups A, B, C and D was proposed by Allan Crocker in 1961 after he and Sidney Farber had expanded the category of Niemann-Pick disease by applying the diagnosis to all patients with "foam cells" and lipid storage in the tissues. This had led to the inclusion of older and less severely affected people than those originally described by Niemann and Pick.
Symptoms common to all types of Niemann-Pick disease include yellow discoloration of the skin, eyes, and/or mucous membranes (jaundice), progressive loss of motor skills, feeding difficulties, learning disabilities, and an abnormally enlarged liver and/or spleen (hepatosplenomegaly). The different types of Niemann-Pick disease are inherited as autosomal recessive traits.
Certain characteristics are common to all types of Niemann-Pick disease. Symptoms may include poor feeding habits, failure to grow and gain weight at the expected rate (failure to thrive), physical and mental impairment, swelling (distention) of the abdomen, and/or vomiting. Abnormal enlargement of the liver and spleen (hepatosplenomegaly) occurs in all types of this disorder, but the severity of the symptoms varies greatly. In some cases, swelling of the lymph nodes may also occur (lymphadenopathy). Some children with Niemann-Pick disease have yellow discoloration of the skin, eyes, and/or mucous membranes (jaundice). Abnormal amounts of sphingomyelin, cholesterol, glycosphingolipids, and bis (monoacylglycero)-phosphate accumulate in the organs of the chest and abdomen. In some cases, affected individuals may experience neurological impairment including loss of speech, impairment of voluntary muscle movements (myoclonus), convulsions, and/or dementia.
Niemann-Pick disease type A is the most common form of the disease. Activity of the acid sphingomyelinase (ASM) enzyme ranges from none to 1% of normal. The abnormal accumulation of fats in various parts of the body occurs in the developing fetus. Between the ages of six months to 12 months, low levels of the enzyme sphingomyelinase results in the abnormal enlargement of the liver and spleen (hepatosplenomegaly) and abnormalities of the nervous system. Affected infants may experience poor feeding habits and failure to thrive, which may become apparent during the first few weeks of life.
Additional symptoms may include abdominal swelling (distention), vomiting, diarrhea, fever (pyrexia), bright red spots in the eyes (macula), and/or a brownish-yellow skin discoloration. Abnormal enlargement of the liver occurs more often than enlargement of the spleen. A gradual decline of motor and intellectual function resulting in a degenerative muscle weakness and floppiness may also occur. An affected infant may lose the ability (regression) to hold his or her head up, sit up, or manipulate objects. In some cases, seizures and uncontrolled involuntary muscle movements (spasticity) may also occur. The severity of the symptoms increases rapidly and life-threatening complications usually occur early during childhood.
Individuals with Niemann Pick disease Type B have ASM enzyme activity that is approximately 10% of normal. Symptoms of Niemann-Pick disease type B begin during infancy or early childhood and typically include an abnormally enlarged liver and spleen (hepatosplenomegaly). Bright red spots in the eyes may be present in some affected individuals. The symptoms of this type of Niemann-Pick disease progress more slowly than other types. Nervous system impairment in type B is minimal in comparison to other types. Affected children have an abnormally slow growth rate and may have an increased susceptibility to repeated lung (respiratory) infections. The severity of Niemann-Pick disease type B varies greatly from case to case.
The onset of Niemann-Pick disease Type C (NPC) usually occurs in children between the ages of three and 10. However, NPC can present at any time from fetal life to late adulthood. Life threatening complications may occur at any time. The liver and spleen are often enlarged (hepatosplenomegaly) in infants and children, but many affected individuals do not have enlarged organs, particularly those who present later in life. Other symptoms include a yellowish discoloration of the skin, eyes, and/or mucous membranes (jaundice), progressive impairment of voluntary movements (because of ataxia, dystonia or ataxia), seizures, and/or tremors. Additional symptoms include an inability to form words and speak clearly (dysarthria); difficulty swallowing (dysphagia), and sudden loss of muscle tone, manifest as head drops or falls, brought on by emotional excitement, particularly laughter (gelastic cataplexy).
A characteristic symptom associated with Niemann-Pick disease type C is difficulty or loss of rapid up and down eye movements (vertical supranuclear gaze palsy). Over time, horizontal rapid eye movements are also impaired, and are eventually lost.
Individuals with Niemann-Pick disease type C are unable to transport lipids efficiently within cells. As a result, excessive amounts of cholesterol and glycosphingolipids accumulate in the liver, spleen, and brain. The slow progression of symptoms generally leads to the loss of mental and motor function in early adulthood. Death usually occurs in the late second or third decade from aspiration pneumonia, but patients have survived into their seventh decade.
Niemann-Pick disease type D (Nova Scotia variant) is biochemically and clinically inseparable from type C, and results from mutations in NPC1 gene. The group was created to define patients who shared a common ancestor from Nova Scotia.
Niemann-Pick disease type E is a variant of Type C but typically does not begin until adulthood. Symptoms may include a moderately enlarged liver and spleen. In most cases, no neurological impairment is present. In rare cases, neurological symptoms may include the impaired ability to coordinate movement (ataxia), progressive dementia, and impaired eye movements (ophthalmoplegia).
Another possible form of the disease, which affects people of Spanish descent, has been named Niemann-Pick disease type F or sea-blue histiocyte disease. The disorder is characterized by abnormal (sea blue) cells in the blood and/or bone marrow. Symptoms may include an abnormally enlarged liver or spleen, scarring of the liver (cirrhosis), and bright red spots in the eyes (macula). Impairment of the neurological system is minimal. It is not clear if this is a mild form of Niemann-Pick disease type B, a separate form of Niemann-Pick disease, or a completely different disorder altogether.
Niemann Pick disease is a group of rare disorders that are inherited as autosomal recessive genetic traits.
Genetic diseases are determined by the combination of genes for a particular trait that are on the chromosomes received from the father and the mother. Recessive genetic disorders occur when an individual inherits the same abnormal gene for the same trait from each parent. If an individual receives one normal gene and one gene for the disease, the person will be a carrier for the disease, but usually will not show symptoms. The risk for two carrier parents to both pass the defective gene and, therefore, have an affected child is 25% with each pregnancy. The risk to have a child who is a carrier like the parents is 50% with each pregnancy. The chance for a child to receive normal genes from both parents and be genetically normal for that particular trait is 25%. The risk is the same for males and females.
Type A and B
Niemann Pick disease types A and B are caused by an abnormality in the gene for acid sphingomyelinase (ASM) that leads to a deficiency of this enzyme.
Symptoms of Niemann-Pick disease types A and B develop due to a deficiency of ASM. This results in the abnormal accumulation of a fatty substance (i.e., sphingomyelin) in various organs of the body including the brain, liver, and/or spleen. In Niemann-Pick disease type B, sphingomyelin rarely accumulates in the brain, which is why Niemann-Pick disease type B is rarely associated with neurological abnormalities.
The defective gene responsible for Niemann Pick disease types A and B has been mapped to the short arm (p) of chromosome 11 (11p15.4-p15.1). Chromosomes, which are present in the nucleus of human cells, carry the genetic information for each individual. Human body cells normally have 46 chromosomes. Pairs of human chromosomes are numbered from 1 through 22, and the sex chromosomes are designated X and Y. Males have one X and one Y chromosome and females have two X chromosomes. Each chromosome has a short arm designated "p" and a long arm designated "q". Chromosomes are further sub-divided into many bands that are numbered. For example, "chromosome 11p15.4-p15.1" refers to band 15.4-15.1 on the short arm of chromosome 11. The numbered bands specify the location of the thousands of genes that are present on each chromosome.
Type C and D
Niemann Pick disease types C and D are caused by an abnormality in one of two specific genes for cholesterol metabolism (NPC1 and NPC2) that leads to a reduction in cholesterol metabolism. The majority of affected individuals have a mutation in the NPC1 gene. Fewer than 15 patients have been identified with mutations in the NPC2 gene.
The symptoms of Niemann-Pick disease type C develop as a consequence of impaired trafficking of cholesterol and other lipids within cells. Free cholesterol accumulates in peripheral tissues (liver, spleen and bone marrow), whereas complex fats (glycosphingolipids) are the predominant stored compounds in the brain. Cholesterol accumulation often leads to a secondary deficiency of acid sphingomyelinase.
The defective genes responsible for Niemann-Pick disease type C, termed NPC1 and NPC2, have been mapped to the long arm (q) of chromosome 18 (18q11-q12) and the long arm (q) of chromosome 14 (14q24.3), respectively. More than 150 different gene mutations have been identified in NPC1. The most frequent mutation, occurring in 15% of cases in Western Europe, is I1061T. Another mutation (G992W) has been found almost uniformly in persons with the Nova Scotia variant (Niemann-Pick disease D). Two affected persons have been identified with gene mutations in the NPC2 gene.
Niemann-Pick disease affects males and females in equal numbers. These diseases have been identified in people of all races.
The number of individuals affected by Niemann-Pick disease type A appears to be higher in families of Ashkenazi Jewish ancestry with one in 80 potentially being carriers for the disease. Type B is also more common in Tunisia, Morocco, and Algeria. According to one estimate, Niemann-Pick disease type B affects approximately 1,000 individuals worldwide.
The prevalence of Niemann-Pick disease type C in Western Europe has been estimated to be 1 in 150,000. More than 300 individuals are affected by Niemann-Pick disease type C in the United States. Type C occurs more frequently in the Spanish-American population of southern New Mexico and Colorado. The term Niemann-Pick disease type D is used to describe a specific population of Acadians from Nova Scotia, Canada, and their descendants.
Symptoms of the following disorders can be similar to those of Niemann-Pick disease. Comparisons may be useful for a differential diagnosis:
Refsum syndrome is a slowly progressive rare disorder of fat metabolism. It is characterized by the abnormal accumulation of phytanic acid in the blood and other tissues of the body. The major features include progressive inflammation and pigmentation of the retina of the eyes (retinitis pigmentosa), burning or tingling sensations in the arms and legs (peripheral neuropathy), the impaired ability to coordinate movement (ataxia), and elevated protein in the fluid that surrounds the spinal cord and brain. Refsum syndrome is inherited as an autosomal recessive trait. (For more information on this disorder, choose "Refsum" as your search in the Rare Disease Database.)
Tay-Sachs disease is a rare inherited disorder that results in the progressive destruction of the central nervous system. In affected individuals, the body is unable to properly metabolize certain fats (lipids) because of the absence of the enzyme hexosaminidase A. This disease is generally found in children of Eastern European Jewish heritage. Symptoms may include an abnormal startle response (reflex), muscle weakness (hypotonia), restlessness, and/or abnormal eye movements. Eventually a child with Tay-Sachs disease experiences a loss of cognitive skills. Tay-Sachs disease is inherited as an autosomal recessive trait. (For more information on this disorder, choose "Tay-Sachs" as your search term in the Rare Disease Database.)
Sandhoff disease is a rare inherited lipid storage disorder resulting in the progressive deterioration of the central nervous system. A deficiency of the enzymes hexosaminidase A and B results in the accumulation of certain fats (lipids) in the brain and other organs of the body. Symptoms in infants may include feeding problems, general weakness, and an exaggerated startle reflex in response to sudden loud noise. Motor delays and mental impairment are progressive. Sandhoff disease is inherited as an autosomal recessive trait. (For more information on this disorder, choose "Sandhoff" as your search term in the Rare Disease Database.)
Gaucher's disease is a rare inherited lipid storage disease that results in the abnormal accumulation of fats (lipid) in the body. The symptoms of this disorder may include bone deterioration, abnormal enlargement of the liver (hepatomegaly) and spleen (splenomegaly), and/or low levels of circulating red blood cells (anemia). People with Gaucher's disease typically have a swollen abdomen due to enlargement of the internal organs. People with Type II Gaucher's disease also experience central nervous system symptoms that may include overextension of the neck, tiredness, and/or the lack of response to outside stimulus (catatonia). Most types of Gaucher disease are inherited as an autosomal recessive trait. (For more information on this disorder, choose "Gaucher" as your search term in the Rare Disease Database.)
Sialidosis is a very rare inherited metabolic disorder characterized by a deficiency of the enzyme alpha-neuraminidase. This disorder belongs to a group of diseases known as lysosomal disorders. Lysosomes are particles bound in membranes within cells that break down certain fats and carbohydrates. The deficiency of alpha-neuraminidase that characterizes sialidosis leads to the abnormal accumulation of certain complex carbohydrates (mucopolysaccharides) and certain fatty substances (mucolipids) in many tissues of the body. The symptoms of sialidosis Type I, which typically begin during the 2nd decade of life, may include sudden involuntary muscle contractions (myoclonus), the appearance of red spots (cherry-red macules) in the eyes, and/or other neurological findings. Sialidosis Type II may begin during infancy or later. It is characterized by the same visual characteristics as sialidosis Type I, as well as other symptoms, such as mildly coarse facial features, skeletal malformations, and/or mild mental retardation. Sialidosis is inherited as an autosomal recessive trait. (For more information on this disorder, choose "Sialidosis" as your search term in the Rare Disease Database.)
The diagnosis of Niemann-Pick disease is made based upon a thorough clinical evaluation, a detailed patient history, and a variety of specialized tests.
The diagnosis of Niemann-Pick disease types A or B is confirmed by a blood test that reveals low levels of the acid sphingomyelinase (ASM) enzyme in white blood cells. DNA testing can be used to identify ASM gene mutations. Carrier testing and prenatal diagnosis are available if a specific ASM gene mutation is identified in an affected family member.
The diagnosis of Niemann-Pick disease type C is made by testing a sample of cells obtained by skin biopsy for their ability to transport cholesterol and other lipids. Transport of cholesterol is determined by measuring the conversion of one form of cholesterol (free cholesterol) to another (cholesterol ester). The process is known as esterification. Storage of cholesterol is demonstrated by staining the cells with a compound that glows under ultraviolet light (filipin). DNA testing can be used to identify over 90% of individuals with a NPC1 gene mutation. DNA testing for NPC2 gene mutations is available on a research basis only. Carrier testing and prenatal diagnosis are available if a NPC1 mutation has been identified in an affected family member.
Treatment for individuals with Niemann-Pick disease is symptomatic and supportive. No specific treatment is available for any type of this disease. Supportive care from these specialists may be helpful: pulmonologist for respiratory problems; cardiologist for heart problems; liver and spleen specialist; nutritionist; physical therapist; gastroenterologist and learning specialist.
Individuals with types C and D are often placed on low cholesterol diets. However, such diets and drugs that lower cholesterol levels in the body have not been effective in halting the progress of the disease.
Genetic counseling will be of benefit for affected individuals and their families.
Information on current clinical trials is posted on the Internet at www.clinicaltrials.gov. All studies receiving U.S. government funding, and some supported by private industry, are posted on this government website.
For information about clinical trials being conducted at the National Institutes of Health (NIH) in Bethesda, MD, contact the NIH Patient Recruitment Office:
Tollfree: (800) 411-1222
Email: email@example.com
For information about clinical trials sponsored by private sources, contact:
Paul Orchard, MD, is the principal investigator for a study being carried out at the University of Minnesota Medical Center of treatment of several inborn errors of metabolism, including Niemann-Pick disease, by bone marrow transplantation. For information, visit the ClinicalTrials.gov web site or contact Dr. Orchard at: (612) 626-2961 or firstname.lastname@example.com.
Actelion Ltd., a Swiss biopharmaceutical company, is studying the drug miglustat (Zavesca) as a possible treatment for people with Niemann Pick type C. Initial research demonstrated that miglustat is crossing the blood-brain barrier and suggests that the drug may be restoring function of brain cells (neurons) affected by the disease process. The study includes both adult and juvenile patients. Further study is necessary to determine the long-term safety and effectiveness of this potential treatment for individuals with Niemann Pick type C. The research is being carried out at Columbia University in the United States and The Royal Manchester Children's Hospital in the United Kingdom. For information, visit the company's web site (www.actelion.com) or contact the company at:
Gewerbestrasse 16
4123 Allschwil
Bone marrow transplantation is being tested as a possible treatment for Niemann-Pick disease (NPD) types A and B. Bone marrow transplantation is not recommended for individuals who have severe neurological symptoms. More research is needed to determine the long-term safety and effectiveness of this procedure as a treatment for Niemann-Pick disease types A and B. For more information about bone marrow transplantation, contact:
Dr. Edward Schuchman
Phone: 212-659-6711
Fax: 212-849-2447
e-mail: firstname.lastname@example.com
The Genzyme Corporation and Mount Sinai Medical Center have completed a clinical trial of enzyme replacement therapy. For more information about this trial, contact:
Dr. Robert Desnick
Phone: (212) 659-6700
Email: email@example.com
Genzyme manufactures acid sphingomyelinase, which was granted FDA orphan drug status in 2000 for the treatment of Niemann- Pick disease type B.
Both Dr. Schuchman and Dr. Desnick are members of the staff of the International Center for Types A and B Niemann-Pick Disease, a newly formed organization that provides information and support for patients with Niemann-Pick disease types A and B, as well as support to scientists and physicians. Contact information is as follows:
Charlene Pearlman
Department of Human Genetics
Box 1498
Mount Sinai School of Medicine
1425 Madison Ave.
New York, NY 10029
Tollfree: (800) 673-4685
Phone: (212) 659-6779
Dr. Carole Oddoux is in the process of setting up a genetic test for Niemann-Pick disease type A. Blood samples are needed from individuals who are known to be carriers of NPD for use as controls in the validation of the test. Please contact Dr. Oddoux if you would be willing to donate such specimens.
Carole Oddoux, Ph.D.
NYU Medical Centre
Human Genetics Prog, MSB 136
550 First Avenue
New York, NY 10016
Phone: 212-263-7621
Fax: 212-562-2642; 212-263-7590
Email: email@example.com
In 2003, the Second International Conference on NPD Type C was held in Tucson, Arizona. Several possible future therapeutic strategies were outlined and, in addition, there is a report on possible gene replacement or repair and other work, including information on continuing research by Dr. Peter Lobel. Dr. Lobel is credited with discovering the NPC2 C gene. This report can be accessed by contacting the National Niemann-Pick Disease Foundation. (See the Resources section of this report for contact information). This foundation's Web site provides other information on recent and current research.
Dr. Marc Patterson, the lead investigator for current research underway at Columbia University on Niemann-Pick disease type C, is available for inquiries from patients and their families. His information is as follows:
Marc C. Patterson, MD
Head, Division of Pediatric Neurology
Columbia University Medical Center
Harkness Pavilion, HP5-542
180 Fort Washington Avenue
New York NY 10032-3791
Phone: 212-305-6038
Fax: 212-305-1253
Email: firstname.lastname@example.com.
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Phone #: 520-577-5106
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Phone #: 301-251-4925
800 #: 888-205-2311
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Home page: http://rarediseases.info.nih.gov/GARD/
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Phone #: 877-621-1122
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Phone #: 571-320-8320
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Phone #: 920-563-0930
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2001 Beacon Street
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P.O. Box 5801
Bethesda, MD 20824
Phone #: 301-496-5751
800 #: 800-352-9424
e-mail: N/A
Home page: http://www.ninds.nih.gov/
Patterson MC. Niemann-Pick Disease, type C. In: NORD Guide to Rare Disorders, Philadelphia: Lippincott, Williams and Wilkins, 2003:485.
Menkes JH., au., Pine JW, et al., eds. Textbook of Child Neurology, 5th ed. Baltimore, MD: Williams & Wilkins; 1995:101-4.
Buyse ML., ed. Birth Defects Encyclopedia. Dover, MA: Blackwell Scientific Publications; For: The Center for Birth Defects Information Services Inc; 1990:1252-3.
Fauci AS, et al., eds. Harrison's Principles of Internal Medicine, 14th Ed. New York, NY: McGraw-Hill, Inc; 1998:2175.
Lyon G, et al., eds. Neurology of Hereditary Metabolic Diseases in Childhood. 2nd ed. New York, NY: McGraw-Hill Companies; 1996:55-57, 238-40.
Pentchev PG, Vanier MT, Suzuki K, Patterson MC. Type C Niemann-Pick disease: a cellular cholesterol lipidosis. In: Scriver CR, et al., eds. The Metabolic and Molecular Basis of Inherited Disease, 7th Ed. New York, NY; McGraw-Hill Companies, Inc.;1995.
Patterson MC, Vanier MT, Suzuki K, et al. Niemann-Pick disease type C: a lipid trafficking disorder. In: Scriver, et al., eds. The Metabolic and Molecular basis of Inherited Disease, 8th Ed. New York, NY; McGraw-Hill Co., Inc.;2000.
Bennett JC, Plum F., eds. Cecil Textbook of Medicine. 20th ed. Philadelphia, PA: W.B. Saunders Co; 1996:
Behrman RE., ed. Nelson Textbook of Pediatrics, 15th ed. Philadelphia, PA: W.B. Saunders Company; 1996:
Adams, RD, et al., eds. Principles of Neurology. 6th ed. New York, NY: McGraw-Hill, Companies; 1997:
Lachmann RH, te Vruchte D, Lloyd-Evans E, et al., Treatment with miglustat reverses the lipid-trafficking defect in Niemann-Pick disease type C. Neurobiol Dis. 2004;654-8.
Naureckiene S, Sleat DE, Lackland H, et al. Identification of HE1 as the second gene of Niemann-Pick C disease. Science. 2000;290:2298-301.
Kolodny EH, Niemann-Pick disease. Curr Opin Hematol. 2000;7:48-52.
Hsu YS, et al., Niemann-Pick disease type C (a cellular cholesterol lipidosis) treated by bone marrow transplantation. Bone Marrow Transplant. 1999;24:103-7.
Jan MM, et al., Nova Scotia Niemann-Pick disease (type D): clinical study of 20 cases. J Child Neurol. 1998;13:75-8.
Liscum L, et al., Niemann-Pick disease type C. Curr Opin Lipidol. 1998;9:131-5.
Carstea ED, et al., Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science. 1997;277:228-31.
Loftus SK, et al., Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. Science. 1997;277:232-5.
Pennisi E, Newfound gene holds key to cell's cholesterol traffic. Science. 1997;277:180-1.
Carstea ED, Polymeropoulos MH, Parker CC, et al. Linkage of Niemann-Pick disease type C to human chromosome 18. Proc Natl Acad Sci USA. 1993;90:2002-4.
Paterson CC, The effect of cholesterol-lowering agents on hepatic and plasma cholesterol in Niemann-Pick disease type C. Neurology. 1993;43:61-4.
Peyrat MF, et al., Prenatal diagnosis of Niemann-Pick type C disease: current strategy from an experience of 37 pregnancies at risk. Am J Hum Genet. 1992;51:111-22.
Levran O, et al., Identification and expression of a common missense mutation (l302p) in the acid sphingomyelinase gene of Ashkenazi Jewish type A Niemann-Pick disease patients. Blood. 1992;80:2081- 7.
Hulette CM, et al., Adult onset Niemann-Pick disease type C presenting with dementia and absent organomegaly. Clin Neuropathol. 1992;11:293-7.
Bayever E, et al., Bone marrow transplantation for Niemann-Pick type 1A disease. J Inherit Metab Dis. 1992;15:919-28.
Filling-Katz MR, et al., Ophthalmologic manifestations of type b Niemann-Pick diseases. Metab Pediatr Syst Opthalmologic. 1992;15:16-20.
Winsor EJ, et al., Genetic and demographic aspects of Nova Scotia Niemann-Pick disease (type D). Am J Human Genet. 1978;30:530-8.
McKusick VA, ed. Online Mendelian Inheritance in Man (OMIM). Baltimore, MD: The johns Hopkins University: Entry No. 257220 Last Update: 10/7/03, Entry No. 607616 Last update 3/13/03, Entry No. 257200 Last Update 3/13/03.
Patterson MC. (Updated 9/10/01). Niemann-Pick Disease, Type C. In: GeneReviews at GeneTests: Medical Genetics Information Resource (database online). Copyright, University of Washington, Seattle. 1997-2003. Available at http://genetests.org (accessed 10/03).
McGovern M. Niemann-Pick Disease. eMedicine.com, topic 2889, last Update 6/6/02.
Report last updated: 2006/05/05 00:00:00 GMT+0


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Jones, Eric
Adult Nonfiction F621.6 .J66 2010
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Offensive Inconsistency Haunts This Team
ChrisTriants | Feb 20, 2013 | Comments 0
Let me say this: I believe in this organization. It's tough to remember that this team is still rebuilding, and the best is yet to come. It's tough mainly because we have seen how well this team can play when they're "on", yet they run hot and cold so often (almost every period is a different story), that you never truly know what you're going to get.
Last night's 3-1 loss to the Ottawa Senators was the perfect example of this, and it's frustrating. It also defines the Islanders' biggest problem throughout the past two seasons. Their offense cannot score goals on a consistent basis, period. It's great to see this team win games with five goals, as they did on Saturday night went Tavares went off, but this team finds a way to follow up that performance with one total goal in a two-game span.
Now, I would love to put their woes on the defense and goaltending, but the thing is, this team is clearly "built" for offense. It's not like Nabby or DiPietro are stealing games, because they haven't stole one this entire season. The Isles shouldn't need to rely so heavily on them, though. Not the way they find opportunities.
The Isles found a way to outshoot their opponent again, only for their offense to come up short again. As much as we want to pin this one of Ricky, truth is, this game was a 2-1 game up until the final three minutes. That third goal was horrible, but the offense's killer instinct was worse.
How many times do I have to hear that they "ran into a hot goalie", because I don't want to hear it anymore. The Islanders threw 38 pucks at Craig Anderson, to score one goal tonight. Ten days ago, the Isles threw 43 shots at Ryan Miller, only to convert twice. It's not like they're having problems finding the net (they average 30.2 shots per game, 9th in the NHL); their offense is just so bi-polar, it's maddening.
Fun fact: the Islanders are now 0-8 when scoring 2 goals or less this season. The Islanders have scored 29 goals in their six wins (4.83 goals per game), but only 17 in their ten losses (1.7 goals per game). Again, they live and die by their offense, and that's because that's how they were built. Their team isn't suited for fine defensive play, but when you look at this roster, you see guys who are supposed to be scoring goals, and they're not scoring them in timely situations.
Did you know the Islanders have failed to score in the first period eight times this season, and in five of those times, they failed to score in the second as well? In five of those eight games, BOTH teams remained scoreless after one. The goalies are giving this team a chance, but the players aren't giving the goalies any support.
The Islanders forwards need to show their killer-instinct. No more of these Josh Bailey crossbars, or Kyle Okposo fanned-attempts. Even Moulson is failing to get a good hold of the puck when he's standing in "his" spot. The Isles need change offensively, and I'm not talking about how their 4th-line is playing. They need an offensive spark, because even JT is human. When he's contained, so is this entire team, and it cannot be this way. Bring up Nino and Nelson. Mix up the lines. Something needs to be done with this offense. If we're going to live and die by the amount of goals we score, we better make sure we can score goals consistently. The fire-power needs to be there, and if our "goal-scorers" such as Kyle Okposo and Michael Grabner are non existent, the Islanders better make sure they have a few guys ready to pick up the slack.
Anyways, who's up for some plus/minus?
Plus: Kyle Okposo played well in the corners last night. He worked hard, and he registered an assist. It was directly a result of his hardwork.
Minus: Kyle Okposo found himself in the penalty box during the second period, which ultimately led to the Senators taking the 1-0 lead. Bad penalty by Kyle for the second straight game.
Plus: Casey Cizikas works his ass off.
Minus: Matt Martin failing to hit a wide open net in the first after great cycling by that 4th-line.
Plus: The Islanders getting 38 shots on net.
Minus: The Islanders scored only once.
Plus: DiPietro had his best start of the season.
Minus: Any positive feeling about it was washed away when he allowed his second soft goal of the night, making it a 2-goal game with just over two minutes to go.
Plus: Travis Hamonic putting six shots on net.
Minus: Two defensemen led this team in shots on goal (Hamonic 6, Streit 5).
Minus: Still taking that extra two seconds to set the puck on their sticks, and then shoot, as opposed to pulling the trigger with golden opportunities.
Minus: Thomas Hickey was beaten a lot last night.
Minus: I don't think I saw Michael Grabner once in this game.
Minus: When that first line runs cold, the whole team runs cold.
Minus: Islanders failing to score in the first two periods, again.
Minus: John Tavares getting frustrated. I don't think it's fair for Islanders fans to already be booking his flight out of NY. He's not going anywhere, but he wants to win, and wants the help now.
The Islanders drop to 6-9-1. They face the red-hot Montreal Canadiens tomorrow night, against another "hot goalie" in Carey Price.
Follow @ChrisTriants
Thanks for reading. Comments are appreciated!
Filed Under: New York Islanders
About the Author: Writes at Islanders Op-Timism. Islanders Season Ticket Holder who tends to see the light at the end of the tunnel. Hofstra Graduate currently working at Portnoy, Messinger, Pearl & Associates. I definitely want to end up working within the world of hockey. Blog: www.IslandersOptimism.com E-Mail: email@example.com Twitter: @ChrisTriants


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Our Mission:
Uniting Midwest contesters into a competitive group that
supports and promotes activity in every aspect of ham radio
contesting by serving as a resource to our fellow club
members, promoting activity in all aspects of radio sport,
and supporting the entire contest community through
sponsorship of operating events and awards.
The Society of
Midwest Contesters formed early
in 1985 with the goal of uniting Midwest contesters
into a competitive group and to further the idea of
radiosporting in the Midwest. From 51 charter
members in the summer of 1985, we've steadily grown
to a membership of over 200 contesters, mainly in Illinois,
Indiana, Iowa, Missouri, and Wisconsin.
We launched our first major club effort in the 1985
November Sweepstakes, winning the Unlimited class.
We repeated in the 1986 SS, and were on our way.
We have claimed one or more club
victories in ARRL contests every year since 1999,
including a 3-peat as SS Unlimited champs in 2000, 2001,
and 2002, as well as and many national and division VHF titles
over the years.
Support SMC
Make Your Donation orPay your Dues ($10) Today
Created and maintained
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|Medical Acupuncture
Medical Acupuncture is performed by a physician who is trained and licensed in conventional Western medicine and has extensive training in acupuncture and Eastern medicine philosophies. This approach allows the doctor to use a combination of both approaches to treat and illness, injury or chronic condition.
Acupuncture involves positioning very thin needles on various points on the body depending on the symptoms or pain of the patient. Accurate placement of the needles draws energy to the desired areas and allows for positive energy flow. Acupuncture can be effective for treating both injuries and chronic conditions.
Originating in China more than 2,000 years ago, acupuncture is one of the oldest, most commonly used medical procedures in the world. Acupuncture can be given at the same time as other treatments, such as conventional Western medicine, osteopathic or chiropractic adjustments, and homeopathic or herbal prescriptions. It is important that your physician-acupuncturist knows everything that you are doing, so he can help you get the most benefits from your treatments.
What Conditions can Acupuncture treat?
- Digestive conditions, including gastritis, hiccups, diarrhea, constipation and gastric hyperacidity
- Respiratory ailments, including sinusitis, common cold, seasonal allergies, asthma and bronchitis
- Neurological and muscular conditions, including headaches, migraines, rheumatoid arthritis, sciatica, acute sprains, tennis elbow and neck/back pain
- Eye conditions such as myopia, cataracts (without complications) and conjunctivitis
- Toothaches, gingivitis, etc.
- Post-Chemotherapy conditions, including fatigue, pain, dry mouth and dry eyes
How many treatments will I need?
The number of treatments needed varies from person to person. For complex or chronic conditions, one or two treatments per week for several months may be recommended. For acute problems, fewer visits may be required. For health maintenance, four sessions a year may be all that is necessary.
Are there any side effects to the treatment?
As energy is redirected in the body, internal chemicals and hormones are stimulated and healing begins to take place. Occasionally, the original symptoms worsen for a few days, or other general changes in appetite, sleep, bowel or urination patterns, or emotional state may be triggered. These should not cause concern as they are simply indications that the acupuncture is starting to work.
It is quite common with the first one or two treatments to have a sensation of deep relaxation or even mild disorientation immediately following the treatment. These pass within a short time and do no require anything more than a bit of rest to overcome.
What are the needles like? Do they hurt?
People experience acupuncture needling differently. Most patients feel only minimal pain or discomfort as the needles are inserted; some feel no pain at all. Once the needles are in place, there is no pain.
Acupuncture needles are very thin and are made from stainless steel. Insertion through the skin is not as painful as injections or blood sampling. The risk of bruising and skin irritation is less than when using a hollow needle, such as those for drawing blood.
Is Acupuncture Covered by Insurance?
Some insurance companies currently cover acupuncture costs, but others do not yet recognize the value of acupuncture. Ask your health insurance company if they currently cover acupuncture.
What is Group Acupuncture?
If you do not have acupuncture benefits through your insurance carrier, we offer group treatments at $40 per session. Performed in chairs with several people in the same room, group treatments are a great way to maintain health while keeping the costs down. They are best for those with musculoskeletal pain and injuries, as the acupuncture points are limited. Only acupuncture points along the lower arms and legs, head, ears, feet and shoulders are used. Patients can expect to sit for 30-45 minutes during the treatment and are welcome to bring headphones to listen to music. Wearing loose fitting clothing so the doctor can easily access acupuncture points is recommended.
Private treatments are recommended for those with complex problems, conditions with emotional aspects or conditions of a private nature.
Sign up for a group acupuncture treatment here, or call us at 775-982-8255 for more information.
Qi Gong with Dr. Chen
What is Qi Gong?
Qi Gong (pronounced "chee gong") is an ancient Chinese movement art somewhat similar to Tai Chi. It is meant to promote health and improve the practitioner's own circulation of Qi (vital) energy within his or her body. The slow and rhythmic movements of Qi Gong are both easily learned and gentle on the body. Qi Gong is comprised of visualizations and external movements that improve health and longevity, as well as energy, balance, circulation, calmness, and focus. No experience necessary to participate. Classes are appropriate for any body type or athletic level. Please wear comfortable shoes and unrestrictive clothing. Please call 775-982-8255 to find out more information and the class schedule for registration.
About Dr. Chen
Howard Chen, MD, FAAMA, is board certified by the America Board of Family Medicine and a fellow of the American Academy of Medical Acupuncture. He received his medical degree from the University of Rochester and completed his residency at the University of Washington. He believes that the patient-provider relationship is that of a partnership, with both sides playing an equal part in health and well-being. In addition, he believes that optimal health care involves the use of all available treatments with have been shown to benefit a particular condition, including both Western and Eastern medical philosophies.
About Dr. Maul
Mary Maul, MD, FAAFP, FAAMA, is a fellow of the American Board of Family Medicine and American Board of Medical Acupuncture. She received her medical degree from Michigan State University College of Human Medicine and completed her residency in Family Medicine at the University of Utah in Ogden, Utah. Acupuncture for Dr. Maul is a way to connect to the patient healing process. She believes that all beings are meant to live their lives to their fullest potential. Disease and pain are a reflection of imbalance. Acupuncture assists in the healing process, connecting the spirit, mind and body. Dr. Maul has a passion for acupuncture. It is not only for pain but for well being.
In The News
Dr. Howard Chen discusses what a patient can expect with medical acupuncture treatment here.


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5 Advantages to Flexible IT Staffing
Part-time and temporary employees are likely to become popular among IT units over the next couple years, according to Robert Half Technology.
This story originally appeared at Information Management.
Provide a Trial Period
If you are considering a new crop of full-time employees, temporary workers provide a trial period for potential new employees. During this part-time work or one-time project, you have the advantage of witnessing the persons strengths.
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LiveLIVE UPDATES: Emergency services respond to explosion in Clacton street
This live event has finished
- Major gas explosion in Cloes Lane, Clacton, just after 8.30am
- Two semi-detached houses are believed to have suffered major damage
- Police: two people suffering from serious burns
Road closures + cordons will remain in place overnight + will be reviewed in the morning #ClactonExplosion— @EssexPoliceUK 05 February 2014
Demolition teams are moving in to pull down what is left of the building. Police say the blast zone will remain cordoned off overnight and the road will stay closed until it is safe. The evacuation centre at Clacton Town Hall will close at 6.30pm.
Anyone else who needs help should contact Tendring Council's 24-hour helpline on 01255 222022.
#Clacton road closure update: Cloes Lane is still closed between B1027 St John's Road and Douglas Road. Flatford Drive is also still closed.— @ECFRS 05 February 2014
Our team in Clacton is equipped with a specially adapted vehicle which provides safe shelter as well as clothing, food and shower facilities— @BritishRedCross 05 February 2014
Nick Alston, police and crime commissioner for Essex, said: "I am saddened to learn of the incident earlier this morning in Cloes Lane, Clacton, in which a number of people were injured, some seriously. My deepest sympathy is with them all.
"Early accounts suggest that there was a rapid and effective response by all the emergency services, to control the aftermath of the explosion, treat the injured, evacuate local people and ensure the wider community was kept safe.
"Our police, fire and medical teams have highly developed emergency plans to ensure that they can respond quickly and professionally to tragedies such as this, and seek to control the harm caused.
"I was briefed on the incident by Chief Constable Stephen Kavanagh soon after it happened. I have been following its development with great concern for those injured, and admiration for the manner in which the emergency services and the local community have responded."
Two people and their pet dogs have taken refuge at Clacton Town Hall following Cloes Lane explosion @Tendring_DC— @JamesDwan 05 February 2014
Our response to the Clacton explosion has included ensuring affected pets are safe and secure.— @BritishRedCross 05 February 2014
Essex Police confirm two people suffered serious burns and another seven suffered minor injuries following gas blast in Clacton— @JamesDwan 05 February 2014
Another photo from John McLellan at the scene:
Aerial images, taken by photographer John McLellan, show the extent of the damage caused by the explosion
Thoughts with everyone involved today in the #ClactonExplosion the emergency services are amazing. #Clacton— @closparks21 05 February 2014
RT @AvonFBU: @ECFRS @EssexFBU Thoughts with all affected by the #ClactonExplosion #fbu— @EssexFBU 05 February 2014
Another picture of fire dog Darcy at the scene (Photo: ECFRS)
Thinking of those involved in the #ClactonExplosion today. Awful scenes...— @yllopx 05 February 2014
12:28pm Wed 5 Feb 14
Tina Reeve says
We have just created a new group on Facebook for support and donations.
Here is Essex Fire dog Darcy searching through the rubble to check no casualties are buried underneath (Photo: ECFRS)
Unbelievable pic from the explosion this morning! The houses have just gone!!#ClactonExplosion http://t.co/paVbz28fZX— @gracielaing91 05 February 2014
Sad and shocking scenes from #Clacton - thoughts with all affected and huge praise for emergency service personnel in our part of #Essex— @jordannewell 05 February 2014
Picture of the house ripped apart by an explosion in Clacton before the incident this morning
Ambulance service: "A man, believed to be in his 70s, was airlifted to Broomfield Hospital in a life-threatening after being anaesthetised on scene by air ambulance paramedics. A woman, believed to be in her 50s, was taken to Broomfield with severe burns.
"The other casualties were taken with serious and minor injuries to CGH. Injuries include burns, and trauma injuries such as broken legs.
"Five ambulances, several ambulance incident officers, the hazardous area response team (HART) and two air ambulances attended the scene and treated casualties on scene before they were taken to hospital."
Ambulance service: "A paramedic response car was at the scene in just over 3 minutes after several 999 calls were received at 8.27am."
Ambulance service statement: "Critical care has been given to two people following a house explosion in Clacton. They have been taken to Broomfield Hospital, and eight others have been taken to Colchester General Hospital (CGH) following the incident in Cloes Lane this morning."
RT @AshKapow: Glad my Nan's ok, although there are still people unaccounted #ClactonExplosion http://t.co/6bh4OVCs47— @AlisonBagley1 05 February 2014
Essex Police say a cordon is up around Flatford Drive junction and Cloes Lane to Hadleigh Road. Nien-Oord closed. Residents can't yet go home. Schools not affected.
ACFO Paul Hill reports a fire investigation is already under way and although not confirmed yet, it appears that gas was involved.
ACFO Paul HIll " The power of an explosion fuelled by gas can be seen here and in the neighbouring streets - it is immense"
ACFO Paul Hill: "Incidents like this show how important it is to make sure gas appliances are well maintained"
Here's a pic of the #Clacton gas explosion aftermath as firefighters control the gas-fuelled fire. Horrific. http://t.co/6rFLf5I1vS— @dave_lambert77 05 February 2014
Last picture comes from Essex Police whose officers are at the scene now.
We now have a gallery of pictures as they come in from the Clacton explosion. It can be viewed by clicking here. Live updates and more pictures as we get them will be added to this live blog as we get them.
#ClactonExplosion: Cordon: Flatford Dv jct + Cloes Lane to Hadleigh Rd. Nien-Oord closed. Residents can't yet go home. Schools not affected.— @EssexPoliceUK 05 February 2014
A fire investigation has started at the scene of the house explosion in Cloes Lane, Clacton. #ClactonExplosion— @ECFRS 05 February 2014
Our first paramedic response car was on scene in just over 3 minutes following the 999 calls been made this morning about #clactonexplosion— @EEAST_Incidents 05 February 2014
Latest statement from the East of England Ambulance Service:
Critical care has been given to two people following a house explosion in Clacton. They have been taken to Broomfield Hospital, and eight others have been taken to Colchester General Hospital (CGH) following the incident in Cloes Lane this morning.
A man, believed to be in his 70s, was airlifted to Broomfield Hospital in a life-threatening after being anaesthetised on scene by air ambulance paramedics. A woman, believed to be in her 50s, was taken to Broomfield with severe burns.
The other casualties were taken with serious and minor injuries to CGH. Injuries include burns, and trauma injuries such as broken legs.
Five ambulances, several ambulance incident officers, the hazardous area response team (HART) and two air ambulances attended the scene and treated casualties on scene before they were taken to hospital.
#ClactonExplosion - another photo from the scene fo the incident in Cloes Lane. http://t.co/fXi0A9cwXX— @ECFRS 05 February 2014
#ClactonExplosion - more pictures from the scene. http://t.co/46xMmUuTkX— @ECFRS 05 February 2014
#ClactonExplosion Seven walking wounded, including 1 young teenager. Electricity turned off and will affect whole street for some time.— @ClactonGazette 05 February 2014
Search dogs, including Darcy ECFRS' fire dog, are being used to ensure everyone has been accounted for and no casualties remain buried.
Statement from Essex Police:
Police have evacuated 19 properties in relation to the explosion in Clacton.
These include ten properties in Cloes Lane, where the explosion occurred, and nine in the road immediately behind the affected property.
There are ten casualties. One is in a life-threatening condition, two are in a severe condition.
The other seven are walking wounded, including one young teenager.
The electricity is going to be turned off and will affect the whole street for some time.
Anyone who is concerned about friends or relatives can contact Essex Police on 101, extension 489803.
10 people have been injured in the house explosion this morning - two seriously. All taken to hospital. Details to follow. #clactonexplosion— @EEAST_Incidents 05 February 2014
#clacton explosion http://t.co/ceKTILJfNL— @shauntrez2 05 February 2014
Statement from the East of England Ambulance Service:
We received several 999 calls to reports of an explosion in Cloes Lane, Clacton at 8.27am this morning (February 5).
We immediately sent five emergency ambulances, one paramedic rapid response car, our hazardous area response team (HART) and several ambulance Incident Officers. Two air ambulances are also at scene and Colchester General Hospitals and Broomfield Hospital have been put on alert.
Our crews are currently assessing the level and nature of injuries of those involved.
We are working closely with other emergency services at the scene, our priority being to get patients to hospital to ensure they receive the expert medical help they need as quickly as possible.
Clacton-Cloes Lane closed between B1027 St John's Rd and Douglas Road after a gas explosion. Flatford Drive has also been closed— @EssexTravelNews 05 February 2014
Here is the location of Cloes Lane, where emergency services were first called just after 8.30am
An Essex Police spokesman said: "Several houses have been damaged. There have been reports of casualties.
"The immediate area is currently being evacuated. People are advised to avoid the area while emergency services deal with the scene."
RT @DouglasCarswell: "@dave_lambert77: Major gas explosion in #Clacton. Details updated as we get them - http://t.co/CES4zQ7E7v" <- any fol…— @LorrainePrice1 05 February 2014
#ClactonExplosion - the evacuation of properties is now complete and the Gas Board are in attendance assessing the scene.— @ECFRS 05 February 2014
RT @EssexPoliceUK: Cloes Lane, #Clacton 8.30am dealing with reports of an explosion. Houses damaged - reports of casualties - immediate are…— @NatashaAgombar 05 February 2014
RT @EEAST_Incidents: Statement on the house explosion in Clacton this morning: http://t.co/Ki7er1X0ny Stay tuned for further updates. #clac…— @AmboOfficer 05 February 2014
Picture from the scene with emergency services in attendance
Explosion was in Cloes Lane - fire service report multiple casualties. Area has been cordoned off. #Clacton— @dave_lambert77 05 February 2014
Major gas explosion in Clacton. Our reporter is at the scene - if you saw or heard anything, or have pics from the scene, let us know.— @ClactonGazette 05 February 2014
One casualty taken on stretcher to air ambulance following explosion in Clacton— @JamesDwan 05 February 2014
Five people have been taken to hospital following a major gas explosion in Clacton.
One is reported to have life threatening injuries and a further five people are being treated at the scene by paramedics.
The blast is believed to have happened in Cloes Lane just after 8.30am today.
Two semi-detached houses are believed to have suffered major damage and a gas-fuelled fire is still burning at the scene.
Other properties were damaged by flying debris.
Neighbours helped pull victims from the rubble.


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Posts tagged Jesus
Posts tagged Jesus
There has been a lot of hype recently over government, government conspiracies, gun control, wars, political elections, etc. It's pretty obvious people are scared. Whether they are scared of predators abusing the law, foreign powers, failing economies, or our own government, one thing is clear: They are vocal about their opinions. I've been accused of seeming apathetic or even ignorant to issues going on in the world because I have remained silent or seemingly passive at times. I've been told to "open my eyes," and "get my priorities straight."
I would like to share my priorities now and explain why I don't really plan on rearranging them.
It's no secret that I am a Christian. If you follow me on Tumblr now, I'd say that's painfully obvious. One of the basics of Christian doctrine is that man is sinful and fallen. For this reason, it should be no surprise when we see corrupt governments and bureaucracies because every person is susceptible to evil desires. Sometimes people worry and freak out over corrupt governments as if this is a new thing, but it's been going on since the very beginning of society. All you have to do is take a look at a history book to see that war, government conspiracies, and corruption have all been around for thousands of years. These characteristics are not unique to one country or to one race or ethnicity. They are human, unfortunately.
So if these are matters of broken humanness and not broken society, what can we do? We could be passive and accept this as fact and then become depressed. Or perhaps there is another solution.
Christianity says man is fallen, yes, but not beyond redemption. God loved His people so much that He Himself took on humanity and lived and died to correct all of the brokenness. Trusting in Him and His work is the salvation of man. God then works in the heart to root out the hate, the corruption, and the greed. In fact, the Bible says this:
2 Peter 1:4 — "Through these he has given us his very great and precious promises, so that through them you may participate in the divine nature, having escaped the corruption in the world caused by evil desires."
So if we trust in Him and escape corruption, what are we supposed to do with the world and these governments still in a mess? The most popular verse on this is when the Pharisees asked Jesus about paying taxes and, essentially, giving allegiance to the government. Famously, He says, "Give back to Caesar what is Caesar's and to God what is God's." (Matthew 22:21; Mark 12:17) In other words, there is a healthy alignment with country and with government, but ultimately you are to separate that alignment from the most important one: the one with Him. Pay your taxes, vote, follow the laws, be a good citizen. But at the end of the day, your body, your mind, and your heart were created by God and belong to Him. Give everything truly important to Him.
Jesus fought the corrupt and oppressive Roman government not with militant force and insurrection nor with money and power, but with Himself. He brought His loving words of life, truth, and freedom through salvation. He took care of widows and the poor. He healed the sick. The only way to cure the disease of corruption was to attack it directly at the human heart, not treat the symptoms that manifest themselves in the broken government and oppression. This was frustrating to His disciples at first. They wanted militant power, but instead, they got the patient, slow, loving Messiah who targeted the very nature of man. This is what we should do, too. This is how we should combat the darkness of the world—with the light of God's truth.
And don't be afraid. At best, the political powers of this world are temporary. The greatest empires have always failed, the most evil dictators have always passed away, and the darkest regimes have eventually died out in time. Christ and His love and power have lasted for centuries and will continue to last for eternity. Ultimately, the government of not only the world but of the universe lies in the very hands that were pierced with nails for you and I.
Isaiah 9:6-7 — For to us a child is born, to us a son is given, and the government will be on his shoulders. And he will be called Wonderful Counselor, Mighty God, Everlasting Father, Prince of Peace. Of the greatness of his government and peace there will be no end. He will reign on David's throne and over his kingdom, establishing and upholding it with justice and righteousness from that time on and forever. The zeal of the Lord Almighty will accomplish this.
This is the promise He has given us. He will rule eternally as the perfect, benevolent King. He will reign with justice, righteousness, and great peace that passes all understanding forever and ever.
I do not fear the powers of this world because they have already been overcome. With Christ's death, He destroyed the dominion of death and evil in the world. My peace with the situation does not mean a naivety or trust for political power, but rather it is a sign of my allegiance with another power all together. I am not afraid of any president, government, or bureaucracy, because my King is the King of Heaven and He reigns eternal.
Yesterday, I was going to The Hobbit with my boyfriend as one of our last dates together before we went our separate ways for the holidays. Before we left, though, we heard about the shootings in Connecticut. I felt incredibly sick to my stomach, not just because these were innocent lives lost, but they were children—the definition of innocence. Also, I want to be a teacher. The reality sunk in that teaching actually has risks, not just for myself but for the students that I love deeply.
Sitting in the movie, I found myself to be angry. I found myself questioning God and having that typical, angry debate with Him after instances like this.
"Why? Why God? Why children?"
No answer.
"He was awful. He was evil."
Still, of course, no answer.
"His evil spilled into the lives of others. They took the punishment he deserved. The blood of the innocent should never be spilled to correct the sins of the wretched."
It was that moment that I caught myself. It was that moment that I think I had my answer. The blood of The Innocent had been spilled to cover all of the evils of the world, and it was the blood of God Himself—God, who humbled Himself, and came as a beautiful, innocent child.
I found myself guilty of the very thing that the disciples of Jesus were guilty of: they wanted a powerful, militant Messiah who would come in and crush opposition and forcibly put everything right. In fact, that's what they thought they had, even after spending all of this time with Jesus and hearing sermons on "turning the other cheek" and "loving their enemies," they went to buy swords during his last week on Earth. They were ready for a military insurrection until Jesus had to gently tell them to put their weapons away. He who lives by the sword dies by the sword. The point is that Jesus had a different kind of salvation in mind, and He was thinking of a different kind of battle—a spiritual one of the heart armed with swords of truth and love.
You see, you don't fight fire with fire, you have to douse it in water and choke the flames out. Then, you have to begin repairing the damage of the fire by planting seeds, tending them, watering them, and working with patience and care. The results of such a process aren't seen for months or maybe even years, but it is the only way to truly reverse the destruction of the flames. God knew that He could come and force His reign. He could come on clouds with terrible lightning and swift justice, but who's to say we would have actually liked that kind of salvation any way? The human heart is so dissatisfied that we might have decided we didn't want to worship a God who would force His rule. No, the only way to root out the evils of the human heart is to patiently and meticulously plant humility and love.
This is the Christmas season. My heart is broken for the families in Connecticut; for little children who will not get to open their Christmas gifts; for families with hearts filled with grief at the empty spots around their tables. In that movie last night, there was one part that stood out to me. Galadriel asks Gandalf why he chose to bring the hobbit Bilbo on their journey, and he said, in so many words, that evil is never vanquished with great strength and force, but with small acts of kindness and a mysterious love and courage against the odds.
Remember that this Christmas season. Remember that God chose a young virgin, He chose to come as a child, He chose things that were unexpected and completely against our ideas of salvation. I'm not saying to not be upset about the awful things that have happened. By all means, be upset. I don't pretend to understand everything that happens in this world. I don't pretend to be okay with these kinds of terrible acts. Yes, I believe that God has purpose and plan, but none of those things are comforting at all in the face of immense pain. Truly grieving is comforting, and I think that's okay. Jesus, God Himself, wept deeply. Tell God you're upset. Be honest about how you feel. But know that the King of the Universe has humbled Himself to a manger and subjected Himself to the darkness of the world so that He could overcome it. Know that He weeps, too.
In fact, that may be the only comfort in such terrible situations. Jesus has felt it, whatever it may be, He's felt it. The good, the bad, the terrible, the happy, the joyful, the sting of betrayal, the thrill of life and the chill of death—He's felt it all. God is Emmanuel; He is with us.
Merry Christmas, friends.
He must increase.
I must decrease.
In my American Literature class, we are reading "The Bell Jar" by Sylvia Plath. My colleagues were commenting on Plath's humor in the book, which came as a shock to me considering she is talking about a character who is breaking down mentally and eventually attempts suicide. The main character, Esther, jokes about trying to hang herself, but she gave up because it was too hard to tie a knot and her ceilings in her house were much too low. Jokes like this actually run throughout the book.
My peers admitted ashamedly that they laughed often while reading the novel, but they didn't know how to take the humor considering she was discussing something as grim as death. Perhaps I am the weird one, but I never once found the book funny, just simply heart breaking. Esther uses humor to cover up the fact that she is very deeply hurt. Humor is often a defense mechanism to cover up insecurity or fear or one's true thoughts. Her jokes only made the situation even more painful and dark to me, because she was showing that she and her author Plath, who based Esther off of herself, were very broken. That dark monster of depression still existed inside, but if Esther could only make the reader or herself laugh, perhaps everyone would forget it or overlook it. Perhaps if we all smiled, we wouldn't have to look at or address the gaping wound. I just wanted to cry for her more.
It seems so painfully obvious to say that appearances are not everything, yet we tend to let ourselves be consistently caught off guard by real life Esthers and Sylvia Plaths. Depression was something that I grew up with and struggled with immensely. I remember admitting my depression and suicidal thoughts at a church retreat in high school and everyone was shocked. They said, "I would have never known. You just always seemed so happy and funny."
I would really love to encourage you guys to do two things:
1.) Get to know people truly and deeply. That is, look beyond their image. Ask them intentional questions about their lives, their interests, their beliefs, their fears, their insecurities, their joys… Notice things about them! Notice when they don't show up for class or church or when they are being a little more quiet than usual, etc… Be observant and be considerate. Don't be intrusive, that is, don't push it or try too hard if someone has put a wall up. But do not merely accept that wall or those smiling faces as all that is to a person.
2.) Love people for exactly who they are and where they are in life. This is seems so overused and cliche at this point, but it is truly the only way to get to know someone and to establish trust with them. You really never know who you can reach if you treat each person just like they are precious, valuable, and irreplaceable.
How do I know this? When I was struggling with depression and when I wanted to commit suicide, I had one friend who sent me an email from Asia who told me randomly how she didn't want to lose me and she loved me. It was funny, because of all the friends and family I had here, she was the only one who could see my brokenness and she was on the other side of the world. She also shared the gospel with me, and though I had heard it one million times, that time was so different, because I actually saw the love of Christ in action through her.
What difference did she make? I didn't kill myself that night.
And I accepted Christ for the first time. She saved my life, but more importantly, she pointed me to the One Who saved my soul. That's all the difference in the world.
People are afraid of love. Romantic love, or even God's love seems overwhelming at times. We're afraid of never finding love, we're afraid of losing love when we do find it, and we're afraid of how that love will change us, as it continues to hang around.
How ironic that 1 John 4:18 says, "There is no fear in love. But perfect love drives out fear, because fear has to do with punishment. The one who fears is not made perfect in love."
When you read the word "perfect" in that passage, it comes from a Greek word -teleios- that refers to something that was laid out, and then completed, like running a race course to the finish line. This word teleios would be stamped on documents to show that a debt was owed, and then was paid on full.
Teleios was the last word Jesus said on the cross.
This is just so beautiful. I needed this.
If you remember nothing else, remember this: The Gospel is for sinners and saints. It's for the thief on the cross and the widow praying at the temple. It's for those who have had abortions and those who are in the pews on Sunday. It's for the liars, the losers, the lame, and the lost. It's for those who cuss and those who have tattoos and drink whiskey. It's for the addict. It's for the girl who sings in the choir. It's for the person struggling with their sexuality. It's for the student who stays up late every night studying. It's for the families who are broken and for the couples who are crazy in love. It's for prostitutes and Pharisees. It's for the hypocrites who say they love Christ, but they don't know a thing about what it means to love Him at all. It's for those who hear about Jesus every day and those who could care less. It's for those who are passionately devoted to God and for those who have given up. The Gospel is for me, but I also want to tell you that it is for you. This list is by no means exhaustive because the Gospel is for everyone. It's for every tribe, every tongue, and every nation. It's for the world because God wants every single human being to know how greatly and enormously they are loved.
Many of my friends who do not believe in Christianity have shared with me their frustrations with Christianity's exclusivity. I guess for me this is an ambiguous term, so I have to break down exactly what they mean by exclusive. Truthfully, most things are exclusive. My University, like most I am sure you know, is exclusive to those who have the certain requirements and prerequisites necessary for admission. Taking that idea a step further, being a full-time student is exclusive to those who take 12 or more hours each semester and pay their tuition. Clubs and organizations are always exclusive. You probably won't have much luck joining the high school band if you can't tell a tuba apart from a trumpet. Sports teams are exclusive to those who follow the rules of the game. In other words, you cannot go into a soccer game and start using your hands and tackling people like in American football to get the ball into the goal. That is outside the confines of the rules of the game. Exclusivity surrounds us in everyday activities, organizations, and groups, so I am pretty certain this is not exactly what bothers people about the "exclusivity" of Christianity.
I think what bothers people most is not the exclusivity of Christianity, but of Christians. Christians, like myself, often make harsh dividing lines between what makes someone a believer and what does not. We like to draw the lines between which sins are acceptable as believers and which are not. Sometimes the statements get even more ridiculous, saying things like "Christians should vote for a specific party or candidate" or "can't have that beer with the guys" or you fill in the blank. If I had a dollar for every time I'd heard one of these statements, I would be able to pay off my college tuition no problem.
Let me be clear with you: Christianity has a set of doctrines and beliefs that should be accepted in order to call yourself a Christian—namely, the belief that Christ is God who died for the forgiveness of every wrong thing we've ever done just so He could have a relationship with us again. Of course there are more, but I can't touch on all of those in one post. Christianity is, in fact, exclusive in this way as anything else is in life. If we could just define Christianity by whatever terms we deemed necessary or right for us, there would not be a Christianity. It would be some vague, nonsensical belief with no real basis.
This being said, the belief of Christianity is not exclusive to one kind of person, which is the point that Christians often confuse. The Gospel of Christ is not for one kind of people group or culture. Jesus said this to His disciples during His last few moments on earth: "You will be my witnesses, telling people about me everywhere—in Jerusalem, throughout Judea, in Samaria, and to the ends of the earth" (From Acts 1:8). This says something very profound about the heart of God: He wants to be available to all people everywhere. Christ Himself was very inclusive in the people He hung out with. I don't know many people, Christian or not, who hang out with a lot of prostitutes, homeless people, lepers, tax collectors, and drunks. But Jesus hung out with all of these guys. If that's not acceptance, then I don't know what is.
If you remember nothing else, remember this: The Gospel is for sinners and saints. It's for the thief on the cross and the widow praying at the temple. It's for those who have had abortions and those who are in the pews on Sunday. It's for the liars, the losers, the lame, and the lost. It's for those who cuss and those who have tattoos and drink whiskey. It's for the addict. It's for the girl who sings in the choir. It's for the person struggling with their sexuality. It's for the student who stays up late every night studying. It's for the families who are broken and for the couples who are crazy in love. It's for prostitutes and Pharisees. It's for the hypocrites who say they love Christ, but they don't know a thing about what it means to love Him at all. It's for those who hear about Jesus every day and those who could care less. It's for those who are passionately devoted to God and for those who have given up. The Gospel is for me, but I also want to tell you that it is for you. This list is by no means exhaustive because the Gospel is for everyone. It's for every tribe, every tongue, and every nation. It's for the world because God wants every single human being to know how greatly and enormously they are loved.
There is nothing exclusive about that.
A friend had this conversation with me the other day, and it really touched me. He asked, "Why do you hang out with me? I've done a lot of horrible things, and it's not like I've hidden them from you. You know all of my stuff. So, if you don't do those things, why did you ever talk to me to begin with?"
I just smiled and said, "You know I am a Christian."
"Yeah, but that's even more reason to avoid me, right?"
"Not at all. It's the opposite. You see, I believe very firmly that who you were yesterday does not define who you are today. I believe that who you are today does not have to be who you are tomorrow. If my worldview is one that says that anyone—even someone like me—can be redeemed, can be made better and new, why wouldn't I think that way when I see you?"
I had the joy and opportunity of telling him that when I see him, I see him as someone whom God loves so desperately. I see him as someone that Jesus Christ gave His life and His blood just to be close to him. I don't think myself better than him by any means because we have different pasts. In fact, I got to tell him how God sees him and how that affects how I see him—a beloved, precious, amazing child of God that He misses so much.
Then, this morning, I found this scripture on my phone first thing:
Isaiah 1:18 — "Come now, let us settle the matter," says the Lord. "Though your sins are like scarlet, they shall be as white as snow; though they are red as crimson, they shall be like wool."
I don't know who this is for, but I feel like I must write this for you. Come now. Settle the matter with Him. He misses you and loves you. He shed His blood for you. It doesn't matter what you have done, so stop making excuses and feeling guilty and trying to get it all together before you come to Him. That's not how it works. He wants your crimson, scarlet, deepest and darkest stains. He wants them so He can wash them before your very eyes and make you white like snow or like the wool of the Lamb. Nothing is too dark for the light of His grace, and no sin is deeper than the matchless love of Christ.
In fact, I'd say that the greatest mistake you can make is to wait a moment longer. Come now.
And wow. I wish you would see yourself the way He sees you—you'd never go back.


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This black wood effect coffee table has a modern look and a black coloured frame. An extra storage shelf gives you more flexibility. The sturdy, practical design is fantastic value for money, and looks great in any room of the house.
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- Eric Mueller
- Long Island City, NY
- United States
Video Delivery Lead, TED.com
This conversation is closed.
What will happen to chopsticks in 1,000 years?
We're all aware that cultures are clashing and mixing faster and faster everyday thanks to new tech like the internet and old tech like migration.
Currently we celebrate cultures by engaging with them at restaurants, festivals and through travel. We are all entertained by the differences; we use chopsticks while eating asian foods, eat our "plates" when eating Ethiopian food, we are brought on stage during a hawaiian luau against our wishes but then in the end have a good time :) (etc, etc)
However, when mixing you eventually come to a blended phase where the soup is one general color. (keeping with the food theme I got goin on…it's almost lunch time)
Do you think that at some point in humanity's future we will put aside cultures and traditions and become one society - a new together culture? If so, is this a good thing?
Is it possible that future generations will only find out today's diverse cultures by asking their AIs?
Will chopsticks or forks still be around in 1,000 years?
10,000 years?
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Mar 11 2011: My prediction: spork proliferation.
Chopsticks will still be around 1,000 years from now in the same way that hammers, spears, and other primitive tools are still around in modernized incarnations. However, there are other eating tools that are probably more adaptive, versatile, and user-friendly than chopsticks. Perhaps the adoption of that new tool will grow over time.. but only if there is a reason for it to grow (new tool is cheaper to make, new tool becoming a fad, scarcity in the production process of chopsticks..etc)
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Rated 4 out of 5Â by mimimosa So comfy but a little too loose I have to say I love the material of this bra and the fact that it has padding, sooo comfortable!! I'm a 34B and usually am a Medium on sports bras but this one feels a little loose. Thankfully it's a solid color so it doesn't look that ugly when you move around. 9/7/14
Rated 5 out of 5Â by Laurie7 This is my second one I really love this bra. Incredibly comfortable - I use it for biking, walking, yoga, Pilates, and the elliptical. Just bought it in a second color. 9/7/14
Rated 5 out of 5Â by gmn27 LOVE! This sports bra is fantastic. I wouldn't wear it for high intensity or high impact workouts, but it's perfect as designed for yoga or light strength training. The fabric and fit are perfect. 2/5/13
Rated 5 out of 5Â by Courtney13 Love this product! Comfortable fabric, seams don't dig in to sides. Love and appreciate the removable cups, which make for easy washing. Would recommend to anyone! 1/30/13
Rated 5 out of 5Â by susanwayne great bra. Have never ordered a bra online before, so I really wasn't sure what I was getting. But I lucked out on this bra. The fit is great, it's not as tight as most sports bras, so I was pleasantly surprised. Love it. 8/7/14
Rated 4 out of 5Â by JL2726 Love the slight metallic look of the gray bra top This sports bra is wonderfully soft and I definitely appreciated the lining in the cups. No more flat chest! I also found that the gray top had an almost metallic shimmer to it, which I LOVED! 2/2/13
Rated 5 out of 5Â by Camio5 Perfection! Tara Stiles has done it again! This short bra is so comfortable and supportive. you hardly feel like you have it on. It doesn't fit too tight like most sports bras do. Love Love LOVE it!! 1/30/13
Rated 5 out of 5Â by Christinad023 I purchased this sports bra to accompany my Yoga Long Bra Tops and I am so glad I did! This sports bra is supportive enough for most workouts- I use it for yoga, strength training, and light cardio- but it is also incredibly soft and comfortable. In fact, I've even slept in mine a couple times. The racerback and neckline perfectly fit with the Yoga Long Bra tops and look great with other tanks as well. This bra features super soft removable cups for varying levels of support and I find that with the cups in, they offer enough support for most activities even as a larger chested woman (36C). I do like my sports bras pretty tight and this feels a little loose, especially by the end of a super hot yoga session, but not enough to be noticeably uncomfortable. This sports bra is definitely a winner and I'll definitely be purchasing more in the future! 12/16/13
Rated 5 out of 5Â by SJliz Comfortable and perfect for Yoga This is the perfect bra for my Yoga class - soft, good support and not tight on my body. 34B - I bought a small and it fits comfortably. I don't like sports bras since they are too tight for me. I wear this for Yoga and dance aerobics and it works out great! I just ordered 3 more. 2/23/14
Rated 5 out of 5Â by Yogayogayoga Perfect for Yoga It does not hold strong but the material is thick enough to support. It is perfect for Yoga. I'm going to buy more. 2/22/14


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I haven't had a chance to use it, but it appears to be the right item for the job.
AR - 10 Receiver Block
Item # WX2-189501
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A strong, safe hold for gunsmithing your AR! AR - 15 or AR - 10 Receiver Block!
These hold your rifle's upper receiver in a bench vise without fear of crushing, marring or scratching the finish.Their story is gripping:
- Machined from tough, long-wearing nylon
- Fits both stripped and barreled, carry handle and flattop receivers with .250" diameter pivot pins
- Holds the receiver at any angle for cleaning, fitting sights and accessories, etc.
- Choice for AR-15 and AR-10 guns.
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Fits standard .223, 6.8 SPC.
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373cc, 44bhp, 105mph, Insurance group
The current market seems littered with new, learner-friendly bikes, which are A2 licence compatible as manufacturers try to get new riders on board. The new 390 Duke may not have the touring ability of BMW's G650GS or the sporty appearance of Kawasaki's Ninja 300, but I think it should win the fun stakes and for most young riders that's where ...
124cc, 15bhp, mph, Insurance group
At £3999 OTR there are cheaper 125s but then none of those rivals have the same heritage or kudos. Despite making only 15bhp it's great fun to ride - the fact the new four-stroke engine thrives on revs keeps the old RS spirit alive. It handles well, stops well, and most importantly looks the part. What more could a 17-year-old ...
125cc, 9bhp, 62mph, Insurance group
The Super 8 125 is probably the most polished feeling scooter that Kymco make. It offers the sportiness of the Agility with the comfort of the Like. The ride has a nice feel to it and the finish on the dash, seat and pipes looks the best of the lot. It's well priced too.
125cc, 8.5bhp, 60mph, Insurance group
The Vity 125 is not a cutting edge scooter. It's not fast. It doesn't look good unless you've got a thing for the 80s. But it does the job and has one big saving grace – a £1,799 price tag which, for a trustworthy 125cc Yamaha, is very cheap.
649cc, 71bhp, mph, Insurance group
The original Kawasaki ER-6f was universally acclaimed by MCN's road testers and the revised ER sees the love affair continue. It's a rare package of fun, practicality and affordability, which is great for novices and experienced riders alike. Its sporty, Ninja looks prove budget doesn't have to mean bland, while revisions to the 649cc parallel twin engine have eradicated most of ...
1584cc, bhp, mph, Insurance group 14
Harley's Wide Glide dates back to the seventies. The new for 2010 bike retains the old-school low-rider looks of long, raked and wide-spaced forks (hence the name Wide Glide), skinny front wheel and minimalist bulk. But what makes the new bike far superior is it has modern handling and ride quality due to frame and suspension updates. The rest of ...
649cc, 72bhp, 130mph, Insurance group 10
The first Kawasaki ER-6n already offered fantastic value for money – fun, practicality and decent looks for £4500. It didn't need a revamp, but for this year it now has a classier more grown up image. The chassis has been tweaked to isolate vibration, and suspension quality was also improved in response to owner comments.
1151cc, 105bhp, 135mph, Insurance group 15
After just two years in production the Moto Guzzi 1200 Sport gets a new engine. So it's out with the old two-valver and in with a new 105bhp four-valve head motor, taken from the Stelvio adventure bike and the Griso 8v cruiser (yes, Guzzi call the Griso an '8v' and all the other bikes in their range with the same ...
248cc, 21bhp, 80mph, Insurance group 6
The Yamaha XV250S Virago is a trusty, reliable and easy to ride option on which to hone your biking skills. If you fancy a big cruiser later on, the Yamaha XV250S Virago is a great place to start: it's got the looks and appears bigger than a 250, so you won't feel left out down at the Ace. The Yamaha ...
124cc, 12.5bhp, 71mph, Insurance group 5
Once upon a time the learner motorcycle world was only filled with two-strokes. And once your eyes had stopped running the only quality trailie was Yamaha's DT125. And it was madly expensive. Nowadays the place is full of four-stroke cheapies like Yamaha's XT125R and we should be grateful. But we're not because de-restricting two-stroke learners was a piece of cake ...
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Unlike in recent years, when the thrust of legislative activity was on regulating abortion, this year legislators seem to be focusing on banning abortion outright.
Last year's attempt to pass a "personhood" bill through the Oklahoma legislature was a disaster. Now, it's a second try.
With three days left to bring the bill up, the senate appears content to let it die.
The development of a potential human life requires conception as a first step. But that is not the same as either pregnancy or personhood. You can't reduce complex reality to a slogan, and when you try to do so, you actually minimize the personhood of women.
The high court turned back the anti-abortion group's plea to put the issue of personhood on the Oklahoma ballot without comment.
Romney running mate Paul Ryan, who's endorsed personhood at the federal level, will have to decide whether to un-endorse the measure or stand behind it.
Why Is Former Personhood Supporter, Congressman Mike Coffman, Ducking Questions About the New Ballot in Colorado?
Rep. Mike Coffman (R-CO) has supported Colorado personhood amendments, which would ban all abortions and some common forms of birth control. Now, he's announced he will not endorse a personhood measure this year. Why not?
In a Newsweek puff piece on Keith Mason, the leader of Personhood USA, the article lets himget away with a few whoppers.
With the rejection of the "Personhood Amendment" in Mississippi and the rejection of Measure 3 in North Dakota, we see proof that Americans have a profound respect for religious freedom as the founders intended it.
The state has less than two weeks to gather 95 percent of their necessary signatures.


text: Easy Run PC code On player 1, game 1, get the kickoff around the 15 yard line then run the ball back down the middle of the field, and wait for a while and let the blockers hold the other team. Then go to the far right of the field (almost out of bounds) and there is a small gap between that final free defensive player and the out of bounds. You run down screen, thru that small gap, and you can return the ball from kickoff to about the opponent's 20 yard line. It's pretty cool because you can do it over and over, because in the one player game, the computer's team always kicks off to you.