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Dr. Fabián Pina Amargós is a first-rate marine scientist from Cuba, who has worked closely with EDF's Oceans program for many years. Fabián has been a scientist with Cuba's Center for Coastal Ecosystems Research for twenty years and was recently named director of the center.
Welcome back for Part 2 of our intern Shannon Switzer's interview with Dr. Fabián Pina Amargós, as they discuss the marine scientist's opinion on the effectiveness of MPA's and ecotourism as conservation tools as well as his hopes for Cuba as a nation. Read the first part of the interview here.
SLS: Some people are skeptical that MPAs are effective in sustaining fisheries while protecting marine life. What have your studies shown you about the effectiveness of MPAs?
FPA: I think that of course, the controversial part is because nature is very variable. Sometimes you can have the results or the positive impacts of a management tool in a shorter time and sometimes it takes longer, which is dependent, for example, on the species you are trying to recover. So a species that has a short life cycle would have an impact of a no-take area faster, but if we are thinking tarpon, or goliath grouper or other species that live longer, you need to wait a longer time [to see the results].
But generally speaking, and especially where I am dealing in the Gardens, which is relevant for Cuba but also for other tropical places with similar ecosystems, we measured the results of the effect of the marine reserve. We found that after ten years of the declaration [of the MPA] the number of fish increased, the size of the fish are bigger and they are more abundant inside of the reserve. Also, they are not shy and are friendlier and allow you to get closer, so you can enjoy them more when you dive. But also, because the number has increased dramatically, we carried out an experiment and tested the spill-over effect, which is when the number of fish increases until it's full inside, and they need to move outside. It's not a random movement, it's basically a density-dependent kind of movement, cause it's crowded inside the protected area, and then they just spill over the boundaries.
Then the fishery grounds benefit from that, and you can fish outside. We've proved that [with our research], but now fishermen are saying most of the fish they are catching now are coming from the reserve. So now the reserves are gaining support by, not all of the fishermen, but many of them. At the beginning the vast majority of them were opposed to the reserve, and it's a normal reaction of human behavior—you are preventing me from using a fishing ground that I've been using forever and my father and my grandfather and my grand grandfather were fishing on—but they realize now that this is a good tool.
SLS: Along the same lines, part of MPA management often involves tourism based on recreational and sport fishing. Do you think these activities should continue to be allowed in protected areas, despite some studies saying that mishandling can sometimes lead to as high as a forty percent mortality rate?
FPA: I think so. What's happening typically is the mortality is a lot lower for recreational fishers, especially if you target tropical places with shallow water areas called flats, like we have in Cuba. These are good fora kind of fly fishing that targets bonefish, tarpon, permit and snook. Basically, you use a very small hook and you need to tease the fish that the thing close to his mouth is real bait—like a real shrimp or a crab or small fish—and then as soon as they bite, you need to hook them, because the fish are not stupid. They feel that it's something sharp, there is no meat in that, and they just spit that out of their mouth. So you need to hook them almost immediately, and if you hook it in the mouth and handle it properly—keep the fish in the water in a horizontal position while unhooking and taking pictures with it—you can get as close as zero percent mortality.
For sure the mortality is less than if you use a net and catch two tons of bonefish. It's very easy to catch two tons of bonefish, because the medium sized ones gather in schools of several hundred individuals, so you can get 5 or 6 tons of bonefish in two minutes [with a net]. Probably you will need like a year or more for hooking a few hundred bonefish.
So I'd say it's viable also because people are willing to pay a lot. Americans, Europeans, people from Argentina, Brazil, Mexico, almost everywhere, South Africa, all those countries that visit the Gardens are good for catching and releasing bonefish. And they pay a lot of money, they pay air tickets, hotels everywhere on their way to the Gardens which benefit our economy and people, and also they tip the guides. The tips are very high, so that money is coming to the coastal communities and having a positive impact on families.
So yes, it is more profitable with less impact. We have tagged a bonefish and caught it again just two weeks later. So in two weeks they are happy to bite again, even with not only hooking them but also putting the tag in the back. So I think it's viable, but of course it is dependent on the fishery.
All the time it is very important to inform people through the media that nature is very case by case, and there are not general recipes for everything. So even in tropical areas to temperate areas similar to one another, there's differences that you must know about and take into account for managing the resources, and that's why it's important to do the research but also to inform people that every place is different and you need to know what is going on in every place to make the best decisions.
SLS: You mentioned that the money from tourism ends up in the hands of the locals and benefits the surrounding community. That is great to hear. Tell me more.
FPA: In Cuba we have been good at gathering the revenues of the country and splitting it quite evenly in the population. So even in the situation of Cuba with limited resources and the embargo and general world situation, we keep the health care, social security and education in very high level related to other countries with similar or even higher income. We have been very good with that.
So even the money that is generated by tourism is well-used in the country, so in general it benefits the entire country, but especially this kind of tourism that involves people from the coastal communities. The issue is that typically the people from the coastal communities, I think almost everywhere, but especially in developing countries, they are not highly educated people, so sometimes it's hard for them to get the positions like in a hotel kind of environment. But these guys are good for marine things- diving and fly fishing- it's impossible for any one of us to compete with these guys on marine related activities. Read More


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Jawatan Kosong Majlis Perbandaran Subang Jaya (MPSJ)
Jawatan Kosong MPSJ
About Majlis Perbandaran Subang Jaya (MPSJ)
Majlis Perbandaran Subang Jaya – MPSJ was established in accordance with the Local Government Act 1976 (Act 171) under section 4. Previously declared as Subang Jaya Municipal Council, it is known as Petaling District Council.
In 1994, the state government has decided to upgrade to the Petaling District Council Council and named as the Subang Jaya Municipal Council. The purpose of this upgrade is to reorganize the administrative organization to pressure on the physical, social, economic and environmental conservation.
Jawatan Kosong Majlis Perbandaran Subang Jaya (MPSJ)
Qualified Malaysian citizens invited to fill the vacancies at Majlis Perbandaran Subang Jaya as follows :
- Pembantu Tadbir (Perkeranian/Operasi) N17
- Penolong Pegawai Tadbir N32
- Penolong Jurutera JA29
- Penolong Pegawai Undang-Undang L29
- Penolong Pegawai Kawalan Alam Sekitar C27
- Pegawai Undang-Undang L41
- Pemandu Kenderaan H11
Further information and how to apply, please follow :
Jawatan Kosong MPSJ Closing Date : 30 April 2014

subset: commoncrawl


text:
Click here to view/print a schedule of all 2014 planned FreeWalker events (updated 7/16/14).
Get organized! Click below to add to your personal calendar, sign up for the event, or just to learn more.
|07-15-2014 08:00:00 07-18-2014 17:00:00 15 "The walk of the world" 4Days Marches Nijmegen Join Ray Smith's marching team for his 17th "Nijmegen:" The oldest, farthest, multi-day, non-competitive march/walk on the planet. A rich 98-year history and a "Bridge Too Far." Registration opens soon and there are only 45,000 slots. Fees & travel. Reservations limited. Get on the FreeWalkers team now. Event: http://www.4daagse.nl/en Signup: http://freewalkers.org/events/the-walk-of-the-world-4days-marches-nijmegen Nijmegen, Holland FreeWalkers - Ray Smith firstname.lastname@example.com false MM/DD/YYYY
|4Days Marches Nijmegen
|08-09-2014 08-09-2014 15 Columbia Trail Twilight/Night Hike Evening hike along the Columbia Trail. Bring headlamp or flashlight, water, snacks. Support vehicle in Califon will have refreshments. Event info: Email Bob firstname.lastname@example.com Signup: http://freewalkers.org/events/columbia-trail-twilight-night-hike High Bridge FreeWalkers - Bob Quninlan email@example.com false MM/DD/YYYY
|Columbia Trail Twilight/Night Hike
|08-16-2014 08-16-2014 15 Connecticut Coastal Walk #3 - 2014 One-day 24-mile walk along the East Coast Greenway and Long Island Sound from Bridgeport to New Haven. Details to follow. Free. Open to public. Event: http://ctcoastalwalk.org Signup: http://freewalkers.org/events/connecticut-coast-walk-3-bridgeport-to-new-haven Starts: South Norwalk FreeWalkers - Nancy Jonap / Ken Kurland firstname.lastname@example.com false MM/DD/YYYY
|Connecticut Coastal#3
|09-27-2014 07:30:00 9-27-2014 18:00:00 15 Endless Summer Walk (bay2ocean30)- 2014 The bay2ocean30 is a unique long distance walk along the interesting and beautiful New Jersey coast covering both the bay and ocean waterfronts. Free. Open to public. Event: http://endlesssummerwalk.org Signup: http://freewalkers.org/events/bay2ocean30-the-endless-summer-walk-2014 Starts: Aberdeen/Matawan Train Station FreeWalkers - Paul Kiczek firstname.lastname@example.com false MM/DD/YYYY
|Endless Summer Walk
|10-13-2014 07:30:00 10-13-2014 18:00:00 15 Lenape34 Walk (The Origins Walk)- 2014 Columbus Day 34 mile walk along the "Lenape Trail" in beautiful South Mountain, Eagle Rock and Mills Reservations. It includes Montclair, West Orange, Verona, Bloomfield, Nutley, and Belleville, and ends in urban Newark. Our fifth annual LENAPE34 is 50% wooded trail and 50% suburban and urban sidewalks and streets. Free. Open to public. Event: http://lenape34.org Signup: http://freewalkers.org/events/lenape34-the-origins-walk-2014 Millburn (starts) FreeWalkers - Paul Kiczek email@example.com false MM/DD/YYYY
|Lenape34 Walk
|10-18-2014 08:00:00 10-18-2014 15:00:00 15 Battle of Short Hills March Approximately 20 mile walk starting in Metuchen following the route of Washington's retreating troops, to Clark, Scotch Plains, stopping at several of the historic sites along the way. Then up into the mountains, along the western edge of the Watchung Reservation, where troops fought the Battle of Bloody Gap. Special historical walk helps commemorate New Jersey's 2014 theme of "Crossroads of the Revolution" Free. Open to public. Event: http://battleshmarch.org Signup: http://freewalkers.org/events/battle-of-short-hills-march Metuchen (starts) FreeWalkers - Paul Kiczek email@example.com false MM/DD/YYYY
|Battle of Short Hills
|11-10-2014 07:30:00 11-10-2014 16:00:00 15 JFK Vets March A 22-mile walk ending at Arlington National Cemetery. This event honors the life of JFK and the lives of others that were given in the service of our country. The route is a circular loop around the district consisting of natural trails, streets and monuments to many who gave their lives to our country. Event: http://jfkmarch.org Signup: http://freewalkers.org/events/jfk-vets-march-2014 Washington DC FreeWalkers - Ray Smith email@example.com false MM/DD/YYYY
|JFK Vets March - 2014
|11-16-2014 11:00:00 11-16-2014 18:00:00 15 Brooklyn Tour & Year-end Party 3rd annual Brooklyn tour of about 8-10 miles area covered TBD. The pace will be easy starts with walk over the Brooklyn Bridge and our final destination is at Sud Vino e Cucina in Bed-Sty. Signup: http://freewalkers.org/events/brooklyn-tour-walk-2014-and-freewalkers-year-end-get-together NYC City Hall Fountain (starts) FreeWalkers - Nancy Jonap email@example.com false MM/DD/YYYY
|Brooklyn Tour & Party
Congrats to our 33 FreeWalkers who completed the 40-mile Great Canal Walk on April 7, 2014.
Congratulations to our 35 hard-core walkers who walked the C&O Canal Towpath in Maryland and West Virginia on 2/8/14.
On a cold January 19th, about 30 hearty FreeWalkers & Hike Morristown members trekked like patriots did in historic winter of 1780.
FreeWalkers organize walking events, walking information and social networking. We welcome everyone.
47 members
18 members
4 members
FreeWalkers is a social network for individuals interested in participating in distance walking events. Our group is free and open to everyone. We encourage each member to accomplish challenging goals as we work together, experience, and promote pro-pedestrian issues.
FreeWalkers is an informal group of individuals who plan interesting and challenging walks and invite others to join but do not accept responsibility for their safety and welfare. Walkers who participate in any event should understand that they are participating separately and should be physically prepared and adequately supplied. Any advice offered makes no claims of expertise. Walking a long distance requires above average physical stamina, necessary rest and adequate food and water; which the walker must be prepared to carry or purchase along the way. We encourage all participants to walk together as a group and to have an emergency phone contact or other means of assistance in case of problems.
October 18, 2014 from 8am to 3pm – Metchen (start)0 Comments 0 Likes
Posted by Paul Kiczek on September 29, 2014 at 3:33pm 1 Comment 1 Like
If you think 50 miles, or even 20, is a long way to walk you will need to reset your idea of the possibilities after reading this article. Appearing recently in the New York Times Magazine, it tells of one woman's solitary journey in some of the most forbidding and challenging places on the planet - just for her own personal discovery.
If this sounds familiar to you - "You tell people what you're doing, and they say,…Continue
Posted by Paul Kiczek on September 4, 2014 at 9:23pm 0 Comments 0 Likes
Here's an interesting article on the association of walking with thinking and writing. It's a unique activity that stimulates the creativity in us while keeping our mind and bodies healthy. Watch for more interesting angles on walking. This stuff just may get popular again!
What is it about walking, in particular, that makes it so amenable to thinking and…Continue
Posted by Paul Kiczek on May 28, 2014 at 11:00am 0 Comments 0 Likes
Regular exercise, including walking, significantly reduces the chance that a frail older person will become physically disabled, according to one of the largest and longest-running studies of its kind to date.
The results, …Continue
Posted by Paul Kiczek on May 1, 2014 at 4:30pm 0 Comments 0 Likes
Construction on a two-mile Lenape Walking Path in Essex County Branch Brook Park is underway.
The path will be made of a rubberized surface and provide park goers with a formal and safe trail through the Northern Division of Branch Brook Park, which…Continue
Posted by Paul Kiczek on April 30, 2014 at 4:59pm 0 Comments 1 Like
Walking generally improves thinking skills, both immediately and in the longer term. Multiple studies have shown better memory and executive functions after walking. Now, a test at Stanford is showing that it also improves creativity. Need a good new idea, go for a walk.…Continue
Posted by Paul Kiczek on March 12, 2014 at 1:00pm 0 Comments 1 Like
The FreeWalkers are spotlighted in this new article in the Rails-to-Trails blog. What a great group! They are worthy of our support and interest.
In America's urban centers and rural areas, walkability is becoming a hot topic. Both the public and public leaders are recognizing the way in which pedestrian-friendly policies and infrastructure can help spur economic…Continue
Posted by Paul Kiczek on January 14, 2014 at 4:38pm 0 Comments 2 Likes
The anthropologist David Raichlen and his team recently studied the movement patterns of one of the few remaining hunter/gatherer tribes, the Hazda tribe of Tanzania. They are still independent and subsist on hunting and gathering food by…Continue
Posted by Ray Smith on January 9, 2014 at 1:00pm 1 Comment 1 Like
Martin Luther King, Jr. is inextricably linked to our FreeWalker Kennedy Walk legacy efforts. His dedicatedly unique life is saluted annually at the MLK Holiday Parade and Peace-Walk, which also commemorates the freedom rights march from Selma to Montgomery, Alabama.
The event starts at the United Black Fund, crosses the Frederick Douglass Memorial Bridge and ends at Shepherd Park. https://maps.google.com/
It is free and all ages are…Continue


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- Home
- Find a degree
- Applying and entry
- Fees and funding
- Careers and employability
- Life at UCL
Digital prospectus
English Linguistics MA
Options: PG Diploma
The English Linguistics MA provides students with the theoretical and practical knowledge needed to describe Modern English, together with appropriate training in academic writing, linguistic argumentation and research methods. Students have access to the Survey of English Usage, an unparalleled resource for research into grammatical repertoire.
Mode of study
- Full-time 1 year
- Part-time 2 years
Tuition fees
- UK/EU Full-time: £8,500
- UK/EU Part-time: £4,250
- Overseas Full-time: £16,750
- Overseas Part-time: £8,500
Application date
- All applicants: 1 August 2014
- Scholarship applicants: 1 February 2014
More details in Application section.
What will I learn?
The MA introduces students to the core areas of the study of English Linguistics, including morphology, syntax, phonetics, phonology and intonation. The programme trains students to use library OPACS, specialised websites, discussion lists, and databases (among them the ICE-GB corpus, based at the Survey of English Usage in the English Department).
Why should I study this degree at UCL?
The department has exceptional resources for the study of English Linguistics. Use of the Survey of English Usage has resulted in many important studies of the grammar, semantics and vocabulary of present-day English.
Excellent library facilities are provided by the UCL Library, Senate House Library and the British Library.
Students undertake modules to the value of 180 credits. The programme consists of three core components (90 credits), two optional modules (30 credits) and a research dissertation (60 credits).
A Postgraduate Diploma (120 credits, full-time nine months) is offered.
Core Modules
All MA Students undertake an independent research project which culminates in a dissertation of 10,000 words. Students have access to the Survey of English Usage for this project.
Teaching and Learning
The programme is taught through seminars and individual tutorials. Student Assessment is through a portfolio of essays (two 2,000-word essays on English grammar), three three-hour written papers and the dissertation. Each of the five components of assessment makes up 20% of the final mark.
Further details available on subject website:
Further information about funding and scholarships can be found on the Scholarships and funding website.
Entry requirements
A minimum of an upper second-class Bachelor's degree in English language or literature, or in linguistics from a UK university or an overseas qualification of an equivalent standard will normally be required.
Some prior knowledge of English language studies (specifically English grammar) are is expected for the programme.
International equivalencies
Select your country for equivalent alternative requirements
English language proficiency level: Good
How to apply
The deadline for applications is 1 August 2014, or 1 February 2014 for candidates who are also seeking funding through the Arts & Humanities Research Council and those seeking UCL funding.
Who can apply?
The programme will be of interest to British and overseas lecturers and teachers of English as a first language or as an additional language, those intending to become educational administrators or to train English teachers and those intending to use the MA as a platform for further doctoral research.
What are we looking for?
When we assess your application we would like to learn:
- why you want to study English Linguistics at graduate level
- why you want to study English Linguistics at UCL
- what particularly attracts you to this programme
- how your academic and/or professional background meets the demands of a challenging academic environment
- where you would like to go professionally with your degree
The programme provides an ideal foundation for those wishing to continue for a research degree in English Language or Linguistics; students who obtain good results in their MA examinations may be considered for the MPhil/PhD programme at UCL (subject to places being available). It is also of interest to those who wish to become teachers or lecturers of English, or those intending to pursue a career in writing, publishing, or editing.
Top career destinations for this programme
- King Saud University, University Teaching Assistant, 2011
- Synovate, Research Executive, 2011
- UCL Language Centre, Course Administrator, 2009
- CIC Language School, Teacher, 2009
- ZHI Company, Translator, 2010
Next steps
Mr James Phillips
Register your interest
Keep up to date with news from UCL and receive personalised email alerts. Register your interest
Make an application
Prospectus subject
Faculty overview
Staff View
"London offers unparalleled resources for all researchers and UCL is fortunate in being just round the corner from the British Library, British Museum and the Wellcome Trust."
Professor Bas Aarts
Professor of English Linguistics
Staff View
"At the moment I am trying to gather together everything that I have ever known for the 18th century volume of the Oxford English Literary History."
Professor John Mullan
Head of Department


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CHAPEL HILL Saturday was another whirl of activity for Carol Folt, UNC-Chapel Hill chancellor-elect, who made the rounds at a science expo, an alumni association meeting, dinner with campus leaders and the spring football game.
She spent the morning with Chancellor Holden Thorp, who seemed to enjoy the role of tour guide. Leading Folt and her husband, David Peart, into the chancellors digs in the historic South Building shortly after 9 a.m., he said, So, this is your office.
Asked to describe Friday, her first day on campus, on a scale from one to ten, Folt said, 20.
The future chancellor heads back to Dartmouth College this week, where she is interim president. She starts the job in Chapel Hill July 1.
In an interview with The News & Observer on Saturday, Folt shared her views on her new role and her leadership style.
Private to public: After three decades at a private college in the Ivy League, Folt returns to her roots at a big public university. She was educated at UC-Santa Barbara, UC-Davis and Michigan State, and having grown up in Akron, Ohio, she was oriented to the Big Ten schools, dominated by large public campuses. These were the places that meant something theyve always felt to me to be the genesis of so many exciting ideas and really important lives. I think I found my way to Dartmouth and had an amazing set of opportunities. You know, its just a wonderful, loving community. But Ive wanted to go back to the bustle of the big public.
Problem solving 101: This week, Folt has been described as a fixer, someone who helped deal with a $100 million budget shortfall at Dartmouth and headed a strategic planning effort at the same time. What is her administrative philosophy? Im a team builder. I do really feel that problems are solved when you bring people together to talk about them. And a lot of that goes back to the roots of being an educator. You dont teach students by just telling them things, you teach them by engaging them in conversation, and every time you do that you learn something. ... I like to work on problems. We are here for that job. And so, even when theyre difficult and personally wrenching, that is one of the real privileges that we have is that people are looking to us to really put (forth) a thoughtful set of answers. They may not always agree, but if people believe you are doing your best, youre genuinely trying to get to that and you have a solution that you can back up with real reasoning, youre providing a service.
On sports: Folt grew up a Big Ten fan and has been a lifelong swimmer. Dartmouth doesnt have the major revenue or public attention that UNC generates from its athletic teams, but it does have 34 Division I sports. She is the Ivy League representative on the NCAA Division I Board of Directors. When asked about the sports she loves, she happened to mention the biggies at UNC-CH. I love basketball. I love football. I fell in love with womens soccer in that first World Cup and Olympics, and so I have been a fan of North Carolina womens soccer forever. ... I can get pretty excited about a game.
On fundraising: Increasingly, university presidents jobs are to bring in corporate and alumni donations. UNC-CH is expected to launch a multiyear fundraising campaign, but Folt said she doesnt view donor cultivation as a chore. I look at these often as educational, learning moments. Youre having conversations, and it is very helpful when you go back and talk with the faculty and the staff to be able to say, Look, this is how were being viewed from outside. What is our answer back? So Ive always found these to be extremely stimulating dialogues.
About politics: Its safe to say that Folt hasnt had much exposure to lobbying lawmakers at the private Dartmouth. Thats about to change, as the legislature and new governor in North Carolina are asking questions and scrutinizing education spending. She said she would work alongside the university boards and UNC system president Tom Ross. I hope to help him as we try to describe why we just feel so passionately that this thing that we do is for the future of the state. So I think thats something that will certainly be part of my learning curve, but Im excited about it.
On moving beyond scandal: Folt doesnt believe the athletics and academic fraud scandals have sullied UNC-CH. She said she interacts with people in higher education across the country and hasnt heard them talk about a decline in the universitys reputation. Its viewed very, very positively in the world. It is thought to be one of the great places. And though you live in a place where you see the issues of immediate consequence in the moment, none of that has tarnished the institution considered one of the great universities in the world.
Stancill: 919-491-8213
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The Lyric Beauty of Eyes
By Rob Taylor
No matter where you look, there they are. In fact, without them, you wouldn't be able to look anywhere, so they're certainly very important. Indeed, as an ever-present part of our lives, the eyes have trickled down into all the spheres of culture – film, literature, art and music – and are frequently employed for their vivid imagery and as a symbol for the things that lie within us. Today, let's delve a little deeper into the ocular world with a look (pun intended) into the presence of eyes in the music that we listen to. Why let the ears have all the fun?
Where to begin? Well, the best place would probably be way back at the dawn of music with the plainsong of the monks of old(e) – unfortunately for us, nobody seems to have bothered to translate their drones into English, so we have no idea whether they're singing about eyes or the price of donkeys. Instead, we'll skip ahead to a time when some genius somewhere invented the lyric. Actually, a few years beyond that, even, to a point where we're all pretty much on even cultural footing. The 1960s, let's say.
(Incidentally, we'll be sticking strictly to the literal sense of the term "eye" here, so don't expect any "Eye Don't Wanna Miss A Thing"s, or "Everything Eye Do, Eye Do It For You"s. If you're in the market for optical puns, though, you've come to the right place.)
Beginning with the swinging sixties, let's take a look at a song by one of the most influential artists of all time – none other than Jimi Hendrix. On his 1968 album Electric Ladyland, Jimi treated us to an aural extravaganza in the form of "Gypsy Eyes." The song mentions our optical apparatus on more than one occasion: "Well, I realize that I've been hypnotized, I love your gypsy eyes / I love your gypsy eyes." Come now, how many times have you found yourself "lost" in someone's eyes? It's a great example of the lofty places our eyes can take us to.
Moving swiftly along, we find ourselves in (nearly) everyone's all-time favorite decade, the 70s. So, which of the plethora of songs from that era have been singled out here? Why, it's arena-rock band Queen with their song "White Queen (As It Began)." Released in 1974 on the album Queen II, the song opens with a significant reference to our body part of choice - "So sad her eyes / smiling dark eyes / so sad her eyes / as it began" - revealing yet another facet of these ubiquitous biological orbs: their ability to convey emotion (or, indeed, their ability to convey conflicting emotions... smiling, yet sad at the same time – those clever things).
Next up, we'll look at "Lyin' Eyes" by the Eagles. Featured on the 1975 album One Of These Nights, the song rolls down a heartbreaking path of Americana gold, passing these lyrics on the way: "You can't hide your lyin' eyes / and your smile is a thin disguise / I thought by now you'd realize / there ain't no way to hide your lyin eyes." This reminds us that these eyes of ours don't always work in our favor, and, more often than not, they'll tell the truth long before we do.
Let's flash forward to the go-go 80s. Shoulder pads, huge hair and Corey Feldman – a glorious era it was (and one which should never, ever be repeated). Amongst this new age of booming business and burgeoning technologies, we find the subject of our next stop: Survivor's "Eye of the Tiger." Released in 1982 as the theme tune to the possibly unnecessary Rocky III, the song was an immediate smash. In this case, the use of the word "eye" seemingly relates to determination and power: "It's the eye of the tiger, it's the thrill of the fight / risin' up to the challenge of our rival / and the last known survivor stalks his prey in the night / and he's watchin' us all in the eye of the tiger." Here, Survivor are using the term to portray a focus on success – never giving up – just like the mighty tiger hunting down his prey.
We're remaining in the 80s for the next eye-popping lyrical extravaganza, and it's one that every woman over the age of sixteen in the entire world should know. Yup, it's "Hungry Eyes" by Eric Carmen, prominently featured in the 1987 flick Dirty Dancing. So, how do our visual sensors work their way into this one? Let's take a look: "With these hungry eyes / one look at you and I can't disguise / I've got hungry eyes / I feel the magic between you and I." The use of the word "hungry" here really is a perfect fit – what better term could there be to describe that sheer buzz you feel when gazing upon someone you really love?
Now it's time to jump back into our time machine (a magic carpet, perhaps a DeLorean – whatever takes your fancy) and head to a far more recent point in time, with female solo artist KT Tunstall's 2004 debut album Eye To The Telescope - and in particular the song "Suddenly I See." Now, whilst this song doesn't mention eyes directly, it does represent the emotionally perceptive nature of our eyes: "Suddenly I see / this is what I wanna be / suddenly I see / why the hell it means so much to me." These words seem to convey a sudden realization – a vision not created by the eyes, but by the heart. Sure, it's a tentative link, but the album title features the word "eye," so it's in!
Heading into even more recent territory now, we find ourselves in the company of one of 2007's biggest R&B stars, Rihanna, with her song "Rush" from the album Good Girl Gone Bad. How do eyes figure into this hip little number? A little like this: "I wanna hold your body close, it's callin' to me / and when I look into your eyes, I'm likin' what I see". This song gives us a glimpse of something a little more lustful and primal – our eyes' power to convey that most basic of our human urges...Any more explanation than that would lead us down a totally different road, and I figure we've got to stay PG here.
Throughout our magical optical journey, we've managed to travel across decades (a few, at least) and see just how important our eyes can be – not only so that you don't bump into walls and tumble down stairs, but also as a means to express what we feel inside, that fire that comes from the love or passion that drives us all. Here, my friends, endeth the lesson – and you've all been exemplary pupils (always go out on a high!)...
OPTI® eSTORIES is a place for eyes, of course - a forum for sharing tips and stories, for offering new vision and perspective, for discussing lifestyle and image, all through the window of our eyes. More than that, though, OPTI® is about celebrating the beauty within all of us, and the way our eyes can be just as unique as we are. Fun and feisty, elegant and soulful. It's all here. It's all OPTI®.
If you have any questions or comments about our articles - or a suggestion for future articles - we'd love to hear from you.


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Politics Blog
Political news, election updates, for San Francisco CA and national politics
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CA Recall Flashback:Tom McClintock on the liberal media (VIDEO)
Rep. Tom McClintock was the conservative conservative's choice for governor in the 2003 California gubernatorial recall. But alas, it wasn't his time. He finished third. But until about two weeks before election day, he still thought he could win. Until then, McClintock believes that conservative voters were behind him, skeptical that fellow GOPer Arnold Schwarzenegger […] [Read More]


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|Comfort Inns Harvey hotels are listed below. Search for cheap and discount Comfort Inns hotel rooms in Harvey, LA for your group or personal travels. We list the best Comfort Inns Harvey hotels so you can review the Harvey Comfort Inns hotel list below to find the perfect place.
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DealFisher via eBay offers the refurbished Nokia Lumia 1020 32GB Windows Smartphone for AT&T (no-contract) in White, Black, or Yellow for $259.99 with free shipping. That's $40 under our May refurb mention and the lowest total price we've seen for this no-contract phone. (It's also at least $128 under the best price we could find for a new one.) It features a 4.5" 1280x768 touchscreen display, Qualcomm Snapdragon S4 1.5 GHz dual-core processor, 2GB RAM, 32GB on-board storage, 41-megapixel rear camera, 1.2-megapixel front camera, 1080p video recording, 802.11n wireless, Bluetooth 3.0, and Windows Phone 8.
A 90-day warranty applies, although it's unclear who backs it.
Refurb Nokia Lumia 1020 AT&T No-Contract Phone
$260 + free shippingSHOP NOW
Posted 1 day 14 hr ago


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Review: Corpse Party: Book of Shadows pens a novel of blood and gore
The original Corpse Party for PSP abandoned players in a haunted school of death and torture, leaving them to explore its rooms by walking sprites around Pokémon-style. Team GrisGris has since scrapped that approach, creating a first-person point-and-click visual novel adventure for Book of Shadows (also for PSP), the second game in the series to enjoy a Western release. The title... Read More


text:
|HAL : in2p3-00706824, version 1
|arXiv : 1203.5615
|Code Bibliographique ADS : 2012MNRAS.tmp.3009B
|Fiche détaillée
|Récupérer au format
|Monthly Notices of the Royal Astronomical Society 423 (2012) 1293-1299
|Intensity and polarization of the atmospheric emission at millimetric wavelengths at Dome Concordia
|E.S. BattistelliG. AmicoA. BaùL. Bergé1É. Bréelle2R. Charlassier2S. Collin1A. CrucianiP. De BernardisC. Dufour2L. Dumoulin1M. GervasiM. Giard3C. GiordanoY. Giraud-Héraud2L. Guglielmi2J.-C. Hamilton2J. Landé3B. MaffeiM. MaielloS. Marnieros1S. MasiA. PasseriniF. PiacentiniM. Piat2L. PiccirilloG. PisanoG. PolentaC. Rosset2M. SalatinoA. SchillaciR. SordiniS. SpinelliA. Tartari2M. Zannoni
|BRAIN Collaboration(s)
|Atmospheric emission is a dominant source of disturbance in ground-based astronomy at millimetric wavelengths. The Antarctic plateau is recognized as an ideal site for millimetric and submillimetric observations, and the French/Italian base of Dome Concordia (Dome C) is among the best sites on Earth for these observations. In this paper, we present measurements at Dome C of the atmospheric emission in intensity and polarization at a 2-mm wavelength. This is one of the best observational frequencies for cosmic microwave background (CMB) observations when considering cosmic signal intensity, atmospheric transmission, detector sensitivity and foreground removal. Using the B-mode radiation interferometer (BRAIN)-pathfinder experiment, we have performed measurements of the atmospheric emission at 150 GHz. Careful characterization of the airmass synchronous emission has been performed, acquiring more than 380 elevation scans (i.e. 'skydip') during the third BRAIN-pathfinder summer campaign in 2009 December/2010 January. The extremely high transparency of the Antarctic atmosphere over Dome C is proven by the very low measured optical depth, <τI>= 0.050 ± 0.003 ± 0.011, where the first error is statistical and the second is the systematic error. Mid-term stability, over the summer campaign, of the atmosphere emission has also been studied. Adapting the radiative transfer atmosphere emission model am to the particular conditions found at Dome C, we also infer the level of the precipitable water vapor (PWV) content of the atmosphere, which is notoriously the main source of disturbance in millimetric astronomy (? mm). Upper limits on the airmass correlated polarized signal are also placed for the first time. The degree of circular polarization of atmospheric emission is found to be lower than 0.2 per cent [95 per cent confidence level (CL)], while the degree of linear polarization is found to be lower than 0.1 per cent (95 per cent CL). These limits include signal-correlated instrumental spurious polarization.
|1 :
|CSNSM - Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse
|2 :
|APC - UMR 7164 - AstroParticule et Cosmologie
|3 :
|CESR - Centre d'étude spatiale des rayonnements
APC - Cosmologie et Gravitation
|Planète et Univers/Astrophysique/Cosmologie et astrophysique extra-galactique
Physique/Astrophysique/Cosmologie et astrophysique extra-galactique
|atmospheric effects – instrumentation: polarimeters – site testing – cosmic background radiation
|Lien vers le texte intégral :
|in2p3-00706824, version 1
|Contributeur : Jean-Christophe Hamilton
|Soumis le : Lundi 11 Juin 2012, 15:55:40
|Dernière modification le : Lundi 17 Septembre 2012, 12:02:06


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Two Argosy University, Sarasota Counseling Programs Receive Continued Grant of Accreditation From CACREP
The Council for the Accreditation of Counseling and Related Educational Programs (CACREP), a specialized accrediting body recognized by the Council for Higher Education Accreditation, has granted eight years continued accreditation to the Master of Arts in Clinical Mental Health Counseling and Doctor of Education in Counselor Education & Supervision programs at Argosy University, Sarasota
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Thank you to those who joined us at the 2012 Bone Bash Ball at the Country Music Hall of Fame & Museum on Friday, October 19th! A great time was had by all and we thank our sponsors, donors and planning committee!
Photo credits Rusty Terry, The Tennessean
Dr. Kurt Spindler
This Halloween-themed affair was complete with decorations, a silent auction, dinner and program with frightfully fun music from the Soul Incision band. We are proud to have honored Dr. Kurt Spindler, Director of Sports Medicine at Vanderbilt University Medical Center for his dedication to patient services, research and education in the field of arthritis.
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FLOWERY BRANCH — The Falcons released defensive tackle Carlton Powell and added quarterback John Parker Wilson to the active roster on Friday.
The Vikings, who released Donovan McNabb yesterday, tried to sign Parker Wilson off the Falcons' practice squad.
Also, running back Michael Turner and Julio Jones practiced today.
We'll have the full injury report posted shortly after 4 p.m.
–D. Orlando Ledbetter, The Atlanta Falcons beat blog
December 2nd, 2011
1:33 pm
Will they still target him?
December 2nd, 2011
1:39 pm
The Falcons are probably planning to trade Wilson, with all the QB's in the league coming down with injuries and the ineffective play of others, there seems to be a market for young QB talent. Could sure use some more draft choices in the upcoming draft. I doubt he will ever play for the Falcons.
December 2nd, 2011
1:47 pm
Falcons must feel like this kid can take over for Redman next yr.
December 2nd, 2011
1:55 pm
Good move, keeping our guys in-house. We should have done the same with Dmitri Nance last year. Hope Powell clears waivers and makes it onto the practice squad.
December 2nd, 2011
1:58 pm
Frazier needs to man up… Ponder and Wilson? That sounds like the stupidity that got Brian Billick run out of Baltimore… Leslie, don't let Musgrave get you fired!!!
December 2nd, 2011
2:04 pm
Well hopefully we'll be able to get something for him if he's trade bait. If I recall we signed him as an undrafted rookie FA. If we can get a 5 or above, that's a good move for us. Most likely I assume we're just grooming him and plan to have him move into Matty's back up in the next year or so and put Redman out to pasture or trade him, he's been solid in the action he saw in 2009.
December 2nd, 2011
2:05 pm
@ Rikus…I don't think they want Nance. He's a free agent now and they had a chance to pick him up. I forgot who they chose instead, I think a back-up o-lineman that's no longer on the squad
December 2nd, 2011
2:20 pm
Is Chris Redman retiring next year? If so we definitely don't need to let go of JPW…we need at least one more QB here who knows our offensive system in case Ryan goes down. If Redman is no longer with the team next year they need to either 1 draft another developmental QB or get an established quality backup QB. As evident by the misfortunes of Houston and or Chicago…you are 1 snap away from having your season ruined if Matt Ryan goes down!
December 2nd, 2011
3:10 pm
Trade him and get some picks for the draft.
December 2nd, 2011
3:19 pm
LOL, look at the picture above. He's throwing the football backwards. Haha…
December 2nd, 2011
3:22 pm
Donovan McNabb wasn't released by the Vikings. He was released from prison.
December 2nd, 2011
3:46 pm
How did Turner look in practice today…will Rodgers start if he is unable to go or will we go with Snelling….
December 2nd, 2011
3:50 pm
@TonyTiger bad snap by the center, but JP as a good grip on it
December 2nd, 2011
5:06 pm
[...] second-year player John Parker Wilson off the Atlanta Falcons' practice squad, according to the Atlanta Journal-Constitution, but Wilson chose the Falcons' offer to join their 53-man roster instead. Then, they claimed [...]
December 2nd, 2011
7:00 pm
Why? Beside being a prototype physical quarterback in teams of height, weight, (should, I say hair & eye color) and great college record, this guy is developmental at best, not roster spot worthy.
He can not play special teams, and how many clip board holders do you need ?
December 3rd, 2011
12:58 am
Hehehe John Parker Wilson would be fit for the Vikings….yeah?
December 3rd, 2011
1:31 am
I hope JPW is trade bait for next season. We can't afford to lose him now.
What we need in the back up role to MR2 is a dual threat QB. A change of pace passer/runner who will give DCs another element to prepare for.
Dimitroff, Smitty and Mularkey are you feeling me man?
December 3rd, 2011
9:31 am
[...] Atlanta Falcons This entry was posted in Atlanta Falcons and tagged active, added, John, Parker, Powell, released, roster, Wilson. Bookmark the permalink. ← My Week 13 Picks for the NFC North Division: A Fan's Opinion (Yahoo! Contributor Network) [...]
December 4th, 2011
9:59 am


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Set on 100 acres alongside 7 lakes, Westlake Apartments in Indianapolis, Indiana, is a peaceful community located just 1 block from I-465 and minutes from Indianapolis International Airport and downtown Indy. We offer studio and 1-, 2- and 3-bedroom apartments on 29 spacious floor plans designed with comfort and convenience in mind. Most homes have a patio or balcony and in-home storage. Select homes have lake views, walk-in closets and ceiling fans, and some homes have been remodeled to include new appliances, counters, cabinets, lighting, flooring, windows and doors. Go for a jog or stroll around the lakes, or head for the lakeside pool, tennis courts or sand volleyball court. Work out in our 24-hour fitness center, located in the lakeside Westlake Clubhouse. Go boating, rafting, fishing or windsurfing. Take your family to the onsite playground. Park in a covered carport or a garage. Our pet-friendly community also welcomes cats and dogs. Call today to schedule a personal tour.
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Georgia Girl
member for 6 years, 6 months, 25 days
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My name is Carol and have lived in Georgia all my life. Residing in N.E. Atlanta for many years and grew up in Hapeville, Georgia.
My Dad began this amazing journey in finding our heritage. While on this journey we had discovered so many relatives and friends.
Peternal Lineage ...
Hape ~ Rogers ~ Puderbach ~ Putnam ~ Hall ~ Naill ~ Ecker ~ Engel ~ Reifsnider ~ King ~ Robbins ~ Thompson ...
Maternal Lineage ...
Hunt ~ Edwards ~ Harris ~ Brown ~ Clay ~ Simmons ~ Wingate ~ Maddox/Maddux ~ Knott ~ LeSueur ~ Stinson ~ Bryant ~ Harper ~ Wyatt ~ Tyler ~ Strother ~ Shy/Shi ~ Chastain ~ Hancock ~ Batte ~ Birchett/Burchett ~ Judkins ~ Polk ~ McLarty ~ Eidson ~ Daniell ...
Most of these memorials are based on personal research from my family history (birth, death, marriage, military & other records). Other information was taken from grave markers or obituaries that I've discovered over the years. Cannot guarantee the accuracy of all these memorials, but believe most of them to be correct.
Will be glad to make memorial transfers upon request that is if related. Would very much like to hear from you and should you have any additional information and if there are any corrections to be made, please let me know.
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Bright Star Cemetery
I just posted a picture of Mrs. Daffin's grave. Please consider this image your property.
Added by
on Sep 18, 2014 2:41 PM
S. Frank
Looking for a photo source
Hi there! I'm trying to find the source material for a photo you put up (sorry, I know this is a tough request, you've posted a lot here!). The picture is of Major John Thomas Hunt (http://www.findagrave.com/cgi-bin/fg.cgi?page=pv&GRid=32305607&PIpi=14569982)
We're a TV show looking to possible use the image on tv, and we want to try and find the copywright holder, if there is one.
Many thanks!
Added by
S. Frank
on Sep 10, 2014 8:11 PM
Presleys in West Hill Cemetery
If you're related to the Presleys in West Hill Cemetery in Grayson County, I'd be happy to transfer them to you. I am only distantly related.
Added by
on Sep 10, 2014 1:44 PM
Thank you so very much for your research and information posted here. When my grandmother passed away years ago I had not gotten enough information from her about her lineage but it seems that you have done the whole half of my maternal grandmother's side!
I am very much interested to be in touch with you and can only leave my email here to be in touch. I'm a doctoral student at the University of Georgia.
w t o d d u g a AT u g a DOT e d u
I would love to hear from you, for I certainly have questions.
My very best.
Added by
on Sep 07, 2014 3:13 PM
Franklin & Susan Naill
Hi, Georgia Girl! I've used quite a bit of your data in my trees. Thank you for all of your work!! When I saw you didn't have photos of a stone that is in my town I went out and took photo of for you. Its for Franklin & Susan Naill. Can I send it to you or add it to your page? - Jen
Added by
on Sep 07, 2014 2:13 PM
Shirley Davis
James Clay
James Clay is my 6th gg father. I am trying to find his grave and his fathers (John Charles Clay) grave. I live in Stone Mountain, GA. I have a lot of information on the Clays.
contact me at firstname.lastname@example.com.
Added by
Shirley Davis
on Sep 04, 2014 10:29 AM
Algernon Cannon
Holland Cemetery
I grew up in Wilkinson County and have done some research on Wilkinson County cemeteries; however, I have never seen anything on the Holland cemetery and it is not listed in the Wilkinson County Cemetery Book. Where is this cemetery physically located? Please reply to: firstname.lastname@example.com.
Added by
Algernon Cannon
on Sep 04, 2014 5:47 AM
Millie Belsher Liebert
McCuin Belcher and Sarah Little
Thank you Carol for so promptly correcting McCuin and Sarah's memorials and updating with the information I sent on my 3rd great-grandparents. Your consideration of the evidence is much appreciated. Millie
Added by
Millie Belsher Liebert
on Aug 31, 2014 6:02 PM
Janis Masters
RE: MICHEAL DICKSON JR and his 2nd wife
I have all the information on that Womack family at my website at Ancestry.
If you are a member of Ancestry, you can click on this "link" to my tree at Ancestry and you will find this Womack family.
Abraham Womack's parents were Richard Womack and Anne Nancy Childer's. His 2nd wife Martha Patsey Watkins was a daughter of William Watkins b.1730 King and Queen,VA and Winnefred unknown.
William Watkins left Hannah and Jude to his daughter Patsey Womack and stated they were already in her possession. Then when Abraham Womack died he stated the same two were to stay with his wife M Womack as they were given to her in her father's will.
I did learn that my Martha Watkins Womack remarried Micheal Dickson Jr and there is a possibility she remarried after his death. I don't have any info about that.
Added by
Janis Masters
on Aug 31, 2014 3:47 PM
Millie Belsher Liebert
McCuin Belcher and Sarah Little
McCuin Belcher was married to Sarah Little - not Sarah Parker; see history of Bark Camp Church www.barkcampchurch.org/detailed-history.html listing McCuin and Sarah as charter members, proving they were already married by the time the church was founded 12 April 1788, the date Sarah Parker was also a charter member.
McCuin and Sarah (Little) Belcher's daughter Nancy (Belcher) Taylor named a son William Little Taylor; their son Robert named a son Abraham Little Belcher, indicative of a close relationship with the Little family.
McCuin was born in Amelia County, Virginia abt 1749; died 1821 in Twiggs County, Georgia. His father was Thomas Belcher; it is my opinion his mother was Elizabeth Mackewen, daughter of William Mackewen of Amelia County. Sarah was born abt 1750 in Edgecombe County, North Carolina; died before 1820 in Georgia. She was the daughter of Abraham Little and Amy Llewellyn. McCuin and Sarah were married in Edgecombe County, N.C.
Information regarding McCuin "Belsher" estate can be seen at Milledgeville Historic Newspapers website http://milledgeville.galileo.usg.edu: legal notice published Dec 18, 1821 in Georgia Journal of estate sale to be held in January 1822; executors were sons Robert and Littleton. A search for Littleton "Belsher" will show his father's estate was finally settled in 1826 per the Feb 12, 1827 issue of the Southern Recorder.
McCuin and Sarah are my 3rd great-grandparents. My Ancestry.com tree is: "Families of Belsher, Belcher, Belser, Belsha & affiliates". I also have more information on McCuin's brother Abraham posted at findagrave memorial # 123134385.
Added by
Millie Belsher Liebert
on Aug 31, 2014 4:45 AM
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Bangalore International airport- 34km (approx.)
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Brigade Millenium Bus Stand- 14km (approx.)
The hotel has modern day facilities to offer which include Conference facilities, Body Treatments, Bus Parking, Massage Services, Dining and Wedding/Banquet facilities. D'Lish Multi Cuisine Restaurant and Bar presents an appetizing array of epicurean delights beneath the canopy of twinkling stars. The President is a massive hall used for Large Conventions, Seminars, Annual Meetings, Product Launches, Exhibitions and Conferences. Jade and Spinel Hall are two exclusive venues ideally suited for Corporate Training programs, Interviews and Personal Functions like Birthdays, Receptions and Kitty Parties. The hotel provides complete leisure with the offerings of body treatments and massage services to revitalize the worn-out body cells. Ample parking space not just allows the smooth placement of cars but equally validates safe bus parking.
Bell Hotel and Convention Centre has a brilliant collection of 72 rooms in three categories, Superior Room, Premium Room and Suite Club. The rooms speak the language of extravagance in volumes and hold a majestic spark within. Provision of High Speed WiFi Internet allows the guests to stay socially updated. Residents can charge their inner senses by using the massage chairs for comfort. Every room has an attached bathroom equipped with Bathrobe, hair dryer and modern amenities. There is installation of Satellite TV with 100 plus Channels and refrigerated mini bar for the expediency of the residents. They can even ask for 24 hour in- room dining to enjoy lavish meal in complete solitude.
Hotel has two Banquet hall "Jade Hall" that can accommodate 150 people, "Spinel Hall" can accommodate 150 people and a Convention Hall "The President" can accommodate 1500 people.
The Bell Hotel and Convention Center has a D'Lish multi-cuisine restaurant that serves flavoursome Indian, Chinese and Continental food. This multi speciality restaurant is a great place to explore world cuisine amidst gleaming interiors.
Cleartrip's hotel ratings take into account numerous factors such as independent rating systems like FHRAI, media recognition and post-trip feedback from our customers. We make all attempts to keep this information up to date, but cannot guarantee service levels at the hotel to be consistent.


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Experimental Drug Turns Off Leukemia Cells
COLUMBUS, Ohio (Ivanhoe Newswire) - Medical experts said every year about 12,000 patients in the United States are diagnosed with chronic lymphocytic leukemia, but a new drug has shown promise for patients who have lost all hope of beating the disease.
It's the simple things, like enjoying the outdoors and taking family vacations that 73-year-old Dennis Hickey can look forward to once again.
"I'm very fortunate, I'm excited about life. I can do my job, I sell houses, I can enjoy the grandkids," Hickey told Ivanhoe.
Hickey has chronic lymphocytic leukemia, or CLL, a common and deadly form of leukemia affecting older adults.
"The prognosis was not good, but I was going to see it through no matter what," Hickey said.
With six months to live, Hickey got to take an experimental drug called Ibrutinib as part of a clinical trial for CLL patients. John Byrd, MD, and professor of medicine at the Ohio State University, co-led the study.
"We have seen a drug come into the clinic that has really helped patients with CLL and related diseases that have been at the end of their life," Dr. Byrd explained.
The drug works by targeting the protein in CLL cells. Without the protein, the cancer can't grow. Doctors say 90 percent of patients have had success with Ibrutinib and side effects are minimal compared to chemotherapy.
"The patients tolerate it very, very well. Many patients say they feel like they did before they had CLL," Dr. Byrd said.
Researchers said Ibrutinib is a game-changer. Hickey says it's a life-saver.
"I'm still here and I'm so thankful," Hickey said.
Researchers said Ibrutinib is not a cure, but if patients follow treatment, they can manage CLL the same way they would manage diabetes or high blood pressure.
The drug is expected to be approved by the FDA in early 2014.
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a type of cancer of the blood and bone marrow. The term "chronic" comes from the fact that it typically progresses more slowly than other types of leukemia and "lymphocytic" comes from the cells affected by the disease — a group of white blood cells called lymphocytes, which help your body fight infection. (SOURCE:http://www.mayoclinic.com/health/chronic-lymphocytic-leukemia)
SYMPTOMS: Many people with CLL have no early symptoms. Those who develop signs and symptoms may experience:
- Enlarged, but painless, lymph nodes
- Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen
- Frequent infections
(SOURCE: http://www.mayoclinic.com/health/chronic-lymphocytic-leukemia)
TREATMENT: A new drug application has been submitted to the FDA for the investigational agent Ibrutinib as a therapy for previously treated chronic lymphocytic leukemia (CLL) and previously treated mantle cell lymphoma (MCL) after the positive results observed in two clinical trials, which showed high response rates to the drug.
The filing for the indication for CLL was based on the results of a phase Ib/II trial, in which 85 patients with relapsed or refractory CLL or small lymphocytic lymphoma (SLL) received Ibrutinib orally once daily, with 51 patients receiving a 420 mg dose and 34 patients receiving an 840 mg dose.
The overall response rate (ORR) in both treatment groups was 71%, with an additional 20% of patients in the 420 mg dose arm and 15% of patients in the 840 mg dose arm experiencing a partial response with lymphocytosis. After 26 months of follow-up, the estimated rate of progression-free survival (PFS) was 75%, and the rate of overall survival (OS) was 83% for all patients, irrespective of the dose. Side effects were minimal and consisted mostly of grade 1 or 2 transient diarrhea, fatigue, and upper respiratory tract infection. (SOURCE:http://www.onclive.com/web-exclusives/NDA-Filed-for-Ibrutinib-in-CLL-and-MCL)
John C. Byrd, MD, Professor of Medicine and Medicinal Chemistry at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute, talks about a new drug to treat Leukemia.
How exciting is this drug?
Dr. Byrd: Ibrutinib has been very exciting. This drug has really helped patients with CLL and related diseases; that have been at the end of their life. We've been able introduce a very well tolerated therapy that's giving patients back their life. How can one not be excited about that?
Can you explain how it works? Does it attack the protein within the leukemia cell?
Dr. Byrd: Ibrutinib works in a unique way and it's a targeted therapy. So leukemia cells, CLL cells, and related leukemia have a protein called Brutons Tyrosine Kinase. Without this protein, malignant B cells, the leukemia cells can't propagate. They can't grow and they can't get stimuli to stay alive. The drug works very uniquely by just affecting predominately the leukemia cells. It's a targeted therapy that doesn't affect the rest of the body, which really contrasts it from chemotherapy, that's been used for decades for the treatment of cancer where you're giving something that's toxic to the whole body. It's just a little bit more toxic to the cancer cells. So the patients can take this medicine for a long period of time and not have the adverse side effects that people would have with chemotherapy.
What about side effects with this drug?
Dr. Byrd: Any drug that we give is going to have side effects. Some nuisance side effects at the beginning of treatment, loose stools, rash, heartburn, but then those generally disappear and then patients often will go back to feeling very well. Many patients will say they feel like they did before they had CLL.
What cancer patients are typically good candidates for this particular drug, is it only leukemia patients?
Dr. Byrd: Thus far the drug has been shown to work in CLL, chronic lymphocytic leukemia and a variety of different B cell lymphomas. The target of ibrutinib is present, the drug has a chance of working and it's worked across several different types of blood cancers at this point.
This isn't approved yet by the FDA, but it's on the road to being approved, is that correct?
Dr. Byrd: That's correct. When it will be approved will more than likely be soon, we hope. It can't be soon enough because we're seeing patients every day that would benefit from this drug and right now the only access to it is on clinical trials.
How many on average are patients out there with CLL?
Dr. Byrd: Approximately twelve thousand new patients with CLL are diagnosed a year in the United States. The prevalence is over a hundred thousand because patients with CLL live for an extended period of time.
The good thing with this drug is although they are still living with it their quality of live does improve?
Dr. Byrd: Yeah, it's a disease that mainly affects the elderly, so patients can live with it for a period of time. However, when it causes the symptoms, the big lymph nodes, the spleen enlarging, the fatigue and other things that's when we treat it. That's sort of when outcome becomes much less favorable where quality of life goes down and that's really where the drug impacts most, because we're giving something that's targeted. It doesn't have the adverse side effects of chemotherapy and produces durable remissions with just taking a pill daily.
It comes in a pill form right?
Dr. Byrd: It's a pill.
Any thoughts about the folks at home that are going to see this and may not have hope or know this is available?
Dr. Byrd: Ibrutinib in CLL has given a lot of hope to patients, to physicians, and to the care givers that care for them. The success of this project has come from pharmaceutical companies, universities and the FDA really working hard to bring forth a – a very exciting and active drug and it's happened very quickly. And I think that's a credit—that's a credit to everybody you know including the regulatory agencies that have really moved this agent very quickly through the pipeline.
Is this a cure?
Dr. Byrd: Ibrutinib does not appear to cure CLL, but it is medicine that patients can go on and potentially convert their disease to being one like high blood pressure or diabetes where they can take an oral medicine and control their disease and live with the symptoms of their disease.
Would you even use the product or give it to someone in your family?
Dr. Byrd: If I had CLL and were at the point that it was time to be treated, I would travel around the world, mortgage my house, do whatever to be able to get on this medicine, because it's really a game changing medicine and it's going to likely eliminate chemotherapy from the treatment of CLL in the future.
The Ohio State University
Lab website: www.cll.osu.edu
- Latest


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15 years
I am a very hands-on teacher.
Teacher of the Year 1999
My degree is an Early Childhood Education. I have been teaching since I was in 1st grade even though I did not obtain my degree until 1998.(LOL)I love teaching and could never imagine myself doing anything else.
I teach 3rd grade and love teaching! I have to make learning fun and meaningful for my students. I incorporate as many skills as possible into each activity I do each day. I feel skills must be taught and tied into everyday life. As you can tell, I am a Pig lover! My classroom is full of pigs and my students and I "OINK" a lot!


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Powell's two new schools were dedicated Thursday with brief ceremonies and open houses.
Principal Ginger Sleep opened the celebration at Southside Elementary. She introduced school board chairman David Northrup, who spoke briefly, thanking all the individuals and companies who had contributed to the design and development of the building. Northrup read a letter a letter from U.S. Sen. John Barrasso congratulating the Park County School District No. 1 for completing the new building.
Fifth-grader Trey Ouellette, president of the Southside student council, echoed Northrup's thanks to those who contributed to the school's construction and then invited those in attendance to tour the school.
"I'm going to use my presidential powers to call in Mrs. Sleep to organize things," Ouellette said, before joining other student council members to lead the tours.
At Powell High School, Northrup opened the ceremonies with thanks, then introduced Barrasso, who spoke about the importance of education and praised the Wyoming Legislature for creating the Hathaway Scholarships for Wyoming students.
"You have great opportunities here," Barrasso told the students in attendance.
PHS student body officers Gavin Mills and McKenzie Danforth spoke about memories of the old building and opportunities for new memories in the new one.
Billie Kasinger, a member of the PHS class of 1961, the first one to graduate from the old school, spoke briefly, telling the students to "remember, the best years of your life are now."
"Be the best that you can be," Kasinger said.
Members of the district school board then stepped forward to cut the ribbon on the new school, and everyone stepped inside to inspect the new facility.


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- Mathew Naismith
- Maryborough
- Australia
This conversation is closed.
Is hydraulic fracturing the answer especially when you take in consideration the environmental impact it is having?
Hydraulic fracturing is polluting the underground water which comes up through the cracks caused by the fracturing of the rock & ends up in our water ways. I think we have enough pollutants to deal with above & below the ground now!!
Showing single comment thread. View the full conversation.
Jan 17 2013: Anyone who is using coal for their electricity, gasoline in their car, using sugar in their coffee or buying plastic from China is promoting devastating ecological damage.
There isn't much that is attractive about Hydraulic Fracturing, but it's a lesser of evils compared to the current fuel production system. Getting the US and Canada off of "foreign oil" would be a big plus, might even help to rebalance the world economy and thin the cash funds away from religious terrorist groups.
Personally, I believe that we have more to fear from the damage done to the Everglades and reef system off the coast of Florida due to the sugar industry, thanks to fertilizers, the canal drainage systems and the clearing of forests... and nobody rallied for the displaced Seminoles.
Jan 17 2013: G'day Addam
Obviously you didn't read & watch the links supplied.....We are polluting the air the ground & now with hyrdaulic fracturing the subterranean basin so whtat's so good about hydraulic fracturing again?
On top of obviously polluting the subterranean basin the toxic wast from the drilling process needs to be disposed of as well.
If the multinationals didn't keep squashing clean free energy inventions I think we would be a lot better of than polluting the subterranean basin with hydraulic fracturing.
Jan 17 2013: I've seen the evidence as presented from both wings, Coke AND Pepsi. I'm a green, btw, total enviro-geek, vegan and all.
And I'd like to agree with you but sentences like "multinationals didn't keep squashing clean free energy inventions" are a real turn off in logical discussion.
They don't exist, your technology gods, it's too close to "conspiracy theory".
I'm not saying "it can't happen"... but I am saying that we are using coal and oil, and your laptop is powered that way just as surely as mine. I don't recall that Tesla ever finished figuring out the "free, clean energy" thing, and Atlas may have shrugged - the fact is that we have been dumping tons of US and allied currency into "securing the Middle East" and the same time our citizens are paying for both sides of the fight. Doesn't matter if we're there for the purpose of securing oil, we buy oil from there regardless.
Hydraulic fracturing is a way of opening a domestic energy source that is cleaner and more efficient than coal or oil. It's not pretty, but neither are the coal mountains or the oil fields. It's not optimal, it pollutes, but imagine if we had been using natural gas powered container trucks instead of diesel for the last 15 years, imagine how much less carbon would be in the air, how much less cash out of the pockets of those multinationals.
As far as i'm aware, the biggest heads in the oil biz are just as aware of the "end of big oil" as the rest of us, perhaps more poignantly so - and some of them have lost the most money on attempts at generating "clean energy" through solar and wind collection.
Of course, windmills face the same "Not In My Back Yard" problem that hydro-frac'ing does, and solar fields take up great swathes of desert, killing fields of cacti and spiny lizards.
We demand energy, we can demand *clean* energy, but we don't stop using dirty energy.
You can't really feel good about your sugar, and eat it too.
Unless you're Ed Begley Jr, of course.
Jan 18 2013: G'day Addam
I agree with you that it is a cleaner alternative than what we have been using however it's just as toxic if not more so. Take a look at this link http://www.mining.com/tag/hydraulic-fracturing/
I'm not into conspiracy theories either however I am in direct contact with a source that confirms that the multinational have stopped such inventions coming onto the markets. If you think about it what would the multinational get out of free clean energy & what would it do to the world economy, of course they will stop such inventions, I think that's obvious.
You seem to have excluded all the toxins that are attributed to hydraulic fracturing, like I said we have already polluted the air the ground & now with hydraulic fracturing the subterranean basin which so many rely on for clean water plus by the sounds of it it's going to run into the sea through underground rivers but it doesn't stop there the toxic material coming out of the wells has to be dumped somewhere as well.
I'm sorry but some people are conned to believe that this is our only alternative to what we have been doing, is space next on the list I wonder?
Showing single comment thread. View the full conversation.


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I recently received a flipper for a tooth I lost. A couple of questions, no one at my current dentist office explained anything about it, how do I store it? clean it? can I eat and drink with it? will I talk funny with it as long as I have it? and most importantly how do I know if it is fit correctly?? Thank you for all your help.
Melanie from Connecticut
Usually a flipper is made as a temporary tooth replacement while you are getting something more permanent made. But sometimes it is provided as a budget solution for missing teeth. If you are going to use it more long-term, you need to exercise some care to prolong its life.
Storage: You can store the flipper in a little plastic case similar to what dentists give patients for bleaching trays or orthodontic retainers. I would ask your dentist if he or she has some of these on hand, and, if not, if they can get you one maybe from an orthodontist or by ordering from a dental supply company. If that's a problem, I think you can find something like that at a drug store.
Cleaning: You can clean it by simply brushing it. If you want to get more fancy, you can get denture cleaning tablets or powders which you would use in a glass or in your storage container.
Fit: Will you talk funny? You shouldn't. It should snap into place and feel comfortable, secure, and unobtrusive. If it doesn't, check with your dentist for an adjustment. It shouldn't get in the way of your normal bite or move around while you're talking.
Flippers aren't made to be strong enough to eat on, though some people try eating things. You can get away with that if the food is soft. But if you do that, excuse yourself immediately to a rest room, take the flipper out, and rinse it off and rinse your mouth. If you don't, over not too much time you will get cavities in all those places where the flipper snaps against your teeth. Do this right away. If you wait 20 minutes, the damage has begun.
This blog sponsored by California implant dentist Dr. Robert Thein
Tags: adjusting a flipper, care for a flipper, cleaning a flipper, Dental flipper


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Drive the sturdy, smooth-riding Junkmobile around the neighborhood on regular collection days, or park beneath the Waste Shooter for a quick fill.
Wheels and hubcaps: Make a hole in the center of each wheel and hubcap. The skewer axles should fit through snugly. Using the same method, create two evenly spaced larger holes near the bottom of each long side of the box.
Push a lid and a cap onto the pointed end of a skewer. Thread the skewer through the holes and attach a second lid/cap pair on the other side, as shown. Trim the excess skewer with wire snips. Repeat for the second set of wheels. Rest the trimmed toilet tube halves over the axles so the truck's contents won't interrupt wheel movement. Tape them down.
Driver's cab: Trim the smaller plastic container so that it fits beneath the edge of the truck body. Pierce holes and use paper fasteners to attach the cab to the body.


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*To receive 20% off your $99 purchase, enter promotion code IPEB49VT at checkout. Promo Code box is located in Step 4 of checkout. Order value must total $99 or more before services, taxes, shipping and handling. Valid online at eastbay.com. Does not apply to prior purchases or open orders and cannot be combined with any other offers. May not be used with purchase of GiftCards or toward team orders. Promotion may be modified or terminated at any time. Certain restrictions may apply. Some items are not eligible for discount and will indicate "excluded from discount" on the product's description page. Offer expires 09/25/2014 (3:59 am CT).
Be the First to Know! Get up-to-the-minute info on the latest product launches, special offers and sales events by signing up for Eastbay emails or by requesting our free catalog.
|The adidas Samba is the classic indoor soccer shoe. Full-grain leather upper provides comfort and soft feel. Die-cut EVA midsole adds lightweight cushioning. Non-marking rubber outsole for use on polished indoor surfaces. Wt. 12.1 oz.


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Maybe this is too easy given the prop. Scroll down to see the video.
Quick thought on your way to seeing the video... maybe someone could have picked a better cover image for the video on YouTube... just sayin'.
Oh, and this video starts with a bonus story on how the song got it's name.


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Designer Karl Lagerfeld is obviously still feeling guilty for saying that Adele was "a little too fat" in an interview earlier this year -- at least, according to the British paper The Sun . The fashion icon reportedly is sending Adele a collection of Chanel handbags to apologize.
A source tells the paper that when Lagerfeld, the head designer for Chanel, found out that Adele has a thing for designer handbags, he told his team to send Adele "the best the fashion house has to offer." Said the source, "He said he really wanted to make it up to her so they could maybe work together in the future. He could see her fronting a campaign for Chanel Mademoiselle bags [in the future]."
The source says that Lagerfeld is "annoyed with himself because he ended up insulting her when he meant to compliment her. He thinks she's beautiful and calls her divine."
In February, Lagerfeld told the publication Metro , "The thing at the moment is Adele. She is a little too fat, but she has a beautiful face and a divine voice." Then, he backtracked, issuing a statement that read, "I'd like to say to Adele that I am your biggest admirer" and claiming that his remarks were "taken out of context from how it was originally published."
Copyright 2012 ABC News Radio


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Back to Document
Partnership for Food Safety Educationhttp://www.fightbac.org
US Food and Drug Administrationhttp://www.fda.gov
Canadian Partnership for Consumer Food Safety Educationhttp://www.canfightbac.org
Public Health Agency of Canadahttp://www.phac-aspc.gc.ca
Benenson A.
Salmonellosis. Control of Communicable Diseases Manual.
American Public Health Association. 1996: 410-414.
Centers for Disease Control and Prevention (CDC). Use of a self-assessment
questionnaire for food safety education in the home kitchen—Los Angeles
County, California, 2006-2008.
Edwards BH. Salmonella and shigella species.
Clin Lab Med. 1999; 19(3):469-487.
Heymann D. Salmonellosis. In: American Public Health Association.
Control of Communicable Diseases Manual.
Koningstein M, Simonsen J, et al. The interaction between prior
antimicrobial drug exposure and resistance in human Salmonella infections.
Antimicrob Chemother. 2010;65(8):1819-1825.
Salmonellosis. Centers for Disease Control and Prevention website. Available at:
http://www.cdc.gov/salmonella/. Updated June 27, 2013. Accessed June 19, 2014.
Salmonellosis. EBSCO DynaMed website. Available at:
https://dynamed.ebscohost.com/about/about-us. Updated January 16, 2014. Accessed June 19, 2014.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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Thursday, December 26, 2013 - 1:39pm
(CNN) — Just like Black Friday started earlier this year, stores are ringing in the after Christmas sales early too. Some opened as early as 5 a.m. and some of the deals are so big, you just might need a sleigh to get all of your goodies home, George Howell reports.
Just when you thought the Holiday shopping frenzy was over, the after Christmas sales are on and this year, it's expected to be bigger than ever.
Some stores like Walmart and Kohl's opened their doors as early as 5 a.m. to anxious shoppers just hours after Christmas.
According to Dealnews, you'll get the best bang for your buck on clothing, brand name HDTV's and Holiday treats and decor.
Kathy Grannis, National Retail Federation, "Discounts will definitely be deep this week. But what you're getting are leftovers. You can guarantee that you'll see some 70-75% off discounts on wrapping paper and Christmas tree trinkets."
The sales aren't just in stores, they're online too, Shopper, "We're doing a lot of Amazon.com. A lot of online shopping."
Retailers like Amazon.com, Old Navy and Saks Fifth Avenue are amping up their "day after Christmas" sales in hopes of cashing in on your Holiday cheer.
Kathy Grannis, National Retail Federation, "The week after Christmas can account for as much as 15% of what retailers see throughout the entire holiday season. So if you add it all up this final week is just as important for retailers as the week before is."
Experts say the 26th is also a big day for gift card purchases with Target customers cashing in their stocking stuffers the most today.
Kathy Grannis, National Retail Federation, "Gift cards for 7 years in a row now have been the most requested item. We're actually expecting gift cards to bring about $28 billion once they've all been redeemed."
For those lugging around that sack of returns, some advice from Consumers Reports:
- Make sure to read your receipt's fine print for the exact window and to see if you can get an extension on Holiday gifts.
- Be on the lookout for re-stocking fees
- Keep in mind some items, like video games and movies, can't be returned once you open them.
If you are heading to stores to make those returns today, Kiplinger's Personal Finance reminds you to bring your state issued ID.
Some retailers may ask to see it, especially if you don't have the receipt, that's a step stores are taking to catch repeat returners.


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Important Upcoming Dates
International Students
March 4: Seniors only: OPT class. Learn how to apply for work in your field after you graduate. 12-1pm Vulgamore Hall Rm. 203
March 7: Spring Break begins
March 24: CPT class, learn about Curricular Practical Training and what you must do to apply. 4-5pm. Vulgamore 203
April 25: Final Coffee Hour of Spring Semester and 2013/14 Academic Year
April 25: Departure Forms, Summer Address Forms and Updated I-20 Requests Due by 5:00 p.m.
Students Interested in Studying Off Campus
March 19: Mandatory Orientation for Students Studying Abroad
March 21: Mandatory Orientation for All Students Intending to Study Abroad Off-Campus in 2014
March 21: $250 Deposit Due for Off-Campus Programs
International Coffee Hour - Open to Entire Campus
Most Fridays in the KC Living Room. Check Back for a Detailed Schedule!
March 7, 2014 3:30-5
March 28, 2014 3:30- 5
April 11,2014 3:30-5
April 24, 2014 final coffee hour for the 2013/14 Academic year~ see you in the fall!


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Crime Scene sells forensic supplies and detective clothing to the public. We are also home to an interactive detective game. | View Crime Scene Cases |
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Evidence Collection Tubes
These large, clear plastic Evidence Collection Tubes can be used for collecting and protecting a variety of evidence.
These tubes are 12" long and 3" in diameter and come with two tuff-pak caps that will not pop off of the clear plastic tube.
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Next, you'll be asked to connect with Twitter. Rest assured, we will never send a tweet from your account
without your permission.
We will send you an email with an invite soon.
Hey @linkedin. Its 2012. Fix your search! Still easier to use google than your own search box to search your site.
and so the AWS chase begins in earnest (finally): Google Elbows Into the Cloud
Google enabling Email Collection boxes in Ad Word placement. Smart.
Apple Chomps At App Store Search? Developers See Shift In Search Results
Google has been on multi year fast follow to keep up with Apple... Google unveils Play,
Puzzling story. Monetization? Its about defending Search share: Android No. 1, But Makes Little Money
See what's Trending Now for @dcstalder


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The Pokémon: Symphonic Evolutions concert tour is coming to Philadelphia on September 19th. We have two sets of concert double-passes to give away to lucky Bulbanews readers!
Pokémon Omega Ruby and Alpha Sapphire are coming this November! Check BNN and Bulbanews for up-to-date Pokémon news and discuss it on the forums or in our IRC channel.
Keldeo (BW Promo 60)
Keldeo (Japanese: ケルディオ Keldeo) is a Water-type Basic Pokémon card. It is one of the BW Black Star Promos.
Card text
Pokédex data
|Keldeo - Colt Pokémon
|4'07" (1.4 m)
|106.9 lbs. (48.5 kg)
|Pokédex entry
|When it is resolute, its body fills with power and it becomes swifter. Its jumps are then too fast to follow.
|かくごを きめることで ぜんしんに ちからが みなぎって すばやくなり とびはねると ざんぞうが みえる。
Release information
This card was released within the Keldeo Box during the month of October 2012. In Japan, this card was given to those who bought 1,000¥ worth of Pokémon Trading Card Game products from stores starting from July 13, 2012, the release date of Freeze Bolt/Cold Flare. An alternate version with the Pokémon Center stamp was made available if this store was the Pokémon Center.
Swords Dance is a move in the Pokémon games that Keldeo can learn. This card's Pokédex entry comes from Pokémon Black 2 and White 2.
|This article is part of Project TCG, a Bulbapedia project that aims to report on every aspect of the Pokémon Trading Card Game.