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1960 Rolls-Royce Silver Cloud II, A complete Rolls Royce Silver Cloud II Saloon, built in 1960, imported in 1961. Two-year renovation recently completed; left... More
1965 Rolls Royce Silver Cloud III LHD '65 Rolls Royce Silver Cloud III LHD, 2 tone silver with black with grey interior, automatic transmission, power... More
In 1968, perhaps the worlds finest sedan on the market was the Rolls Royce Silver Shadow. In its fourth year of production, the British... More
1965 Rolls Royce Silver Cloud III LHD long wheel base factory partition Excellent original car for restoration . For only $34,500.... More
1964 Rolls Royce Silver Cloud III LHD '64 Rolls Royce Silver Cloud III LHD, a beautiful color combination of two-tone silver with burgundy and burgundy interior. A... More
1967 Rolls Royce Silver Shadow Coupe Coachwork by H J Mulliner, Park Ward Ltd. Left Hand Drive – This vehicle comes in white with burgundy interior.... More
This 1962 Rolls-Royce Silver Cloud is a lovely long wheel base model in well preserved, mostly original condition. The car was purchased new in... More
A rare LWB Cloud III without division window this is a great original car. This vehicle just arrived. A complete description is coming soon.... More
For sale is a 1967 Rolls Royce Silver Shadow located in our Indianapolis showroom. Rolls Royce produced the Silver Shadow model from 1965 to... More
1969 Rolls-Royce Silver Shadow Sedan VIN: SRX 6150 Showing 90,000 miles on the odometer which appears to be original. The Rolls-Royce Silver Shadow was a striking... More
1966 Rolls Royce Silver Shadow Coupe RHD '66 Rolls Royce Silver Shadow Coupe, RHD, 2 tone silver with navy blue and white interior, desirable chrome... More
1961 Rolls Royce Silver Cloud II. Black with red interior. Left hand drive. Rust free CA car. Runs and drives well. For only $29,500.... More
1966 Rolls-Royce Silver Shadow with 84k original miles and good working original engine. All original parts in and out. Power windows and locks. Original... More
1962 Rolls Royce Silver Cloud II LHD '62 Rolls Royce Silver Cloud II, Left hand drive, black with tan interior, excellent color combination, A/C, and... More
Introduced in 1959 to replace the Silver Wraith Rolls-Royce revived a storied name when it created the Phantom V. Based on a conventional frame... More


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Sunny Hill Trigger Guard Remington 700 ADL Stainless Steel
Product #: 463515 Sunny Hill #: 125
Product Information
High quality replacement steel trigger guard bow from Sunny Hill. This trigger guard is by no means a drop in fit and will require extensive fitting. Gunsmith installation is recommended.
Delivery Information
Shipping Weight: 0.150 PoundsXThe total weight of the product, including the product's packaging as it sits on our shelf. Since some products ship directly from the Manufacturer, their weight may be unavailable. Because of variations in the manufacturing process, similar products may have differing weights. Unless the product is designated as "Ships Alone", Shipping Weight does not include the shipping box or packing materials associated with your order.
Ships Alone: NoXProduct ships from MidwayUSA, separate from any other products on your order due to its size. Products that are Shipped Alone incur separate "Per Order" and "Per Pound" shipping charges.
DOT-Regulated: NoXProduct is regulated by the US Department of Transportation (DOT) and cannot be shipped via USPS or air shipping methods. DOT-Regulated products must ship UPS Ground.
Carrier Restrictions: NoXProduct is restricted by shipping carriers and cannot be shipped to certain locations or via certain shipping methods.
HazMat Product: NoXAdditional shipping charge for HazMat products. Carriers charge extra to ship packages with products they consider hazardous, such as reloading powder and primers.
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The statements and opinions expressed within Customer Reviews reflect each author's personal perspective and do not imply endorsement by MidwayUSA, its Employees or any other organization. Customers should in no way infer that MidwayUSA has validated review information as safe, accurate or appropriate.
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subset: commoncrawl


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Profile and Contact Information |
| Laboratory
Research Program
Our long-term goal is to elucidate basic mechanisms of eukaryotic transcription control and clarify how these controls are subverted during oncogenesis. Ultimately, we hope to use such information to identify points of oncogenic susceptibility within the cell and thus identify potential targets for pharmacologic intervention. We employ biochemical, molecular, and cell biological approaches to study the regulation of eukaryotic RNA polymerase II transcription.
Research Projects
1. Function and regulation of the human transcriptional Mediator
Transcription is central to most cellular processes, both normal and pathologic. For protein-coding genes, transcription by RNA polymerase II is a principal step targeted for regulation within the cell. Gene-specific transcription factors regulate transcription initiation through interactions with chromatin-modifying activities or the general transcription machinery in order to enhance or repress nucleosome-mediated promoter repression and transcription pre-initiation complex formation, respectively. Work over the last decade has established that a central component of the general transcription machinery is Mediator, an evolutionarily conserved multiprotein interface between gene-specific transcription factors and RNA polymerase II. In this capacity, the Mediator occupies a centrally important role in the expression of most eukaryotic protein-coding genes. Originally identified biochemically in the yeast Saccharomyces cerevisiae, we were among the first to identify from human cells a metazoan homolog of the yeast Mediator termed human Mediator (hMediator). We were the first to link the metazoan Mediator to the control of cell-fate specific gene transcription during development and among the first to implicate the Mediator as an end-point in signal transduction pathways. Our work along with that of others has led to the current concept that metazoan Mediators specify unique transcriptional control mechanisms that underlie, at least in part, the advanced complexity of multicellular organisms. We are actively engaged in biochemical studies pertaining to the following issues with respect to hMediator: (1) the precise mechanism by which eukaryotic activators and repressors interface with hMediator to effect activation or repression of transcription; (2) the precise physical and functional interactions among individual Mediator subunits; and (3) how developmental and oncogenic signaling pathways converge on hMediator and how these signals are, in turn, relayed to RNA polymerase II. These studies should reveal novel insight into underlying mechanisms by which cellular phenotype is specified.
2. BRCA1 and transcription control in the DNA damage response.
A major focus of our ongoing research aims to understand how inactivation of the human breast cancer susceptibility gene product BRCA1 leads to breast tumorigenesis. BRCA1 ensures global genome stability through its dual participation in DNA double-strand break repair and transcriptional regulation of DNA damage-inducible genes. This work aims to understand how the caretaker function of BRCA1 is subserved by its role in transcription control. To this end, we have been studying the functional interaction between BRCA1 and ZBRK1, a sequence-specific DNA-binding transcriptional repressor of the DNA damage-inducible GADD45 gene that functions in G2/M cell cycle checkpoint control. Our studies show that BRCA1 functions as a co-repressor of ZBRK1 by targeting the two hallmark features of ZBRK1 as a sequence-specific transcriptional repressor – its ability to bind sequence-specifically to DNA and its ability to repress transcription once bound to DNA. In addition to GADD45, potential ZBRK1 binding sites have been identified in other DNA damage-inducible genes, indicating a prospective global role for ZBRK1 and BRCA1 in the coordinate regulation of DNA damage-response genes. We are actively engaged in the following biochemical and cell biological studies to further define the mechanism and regulation of BRCA1-dependent ZBRK1 transcriptional repression: (1) the influence of BRCA1 on the DNA-binding affinity and specificity of ZBRK1; (2) the identification and characterization of the complete co-repressor network through which BRCA1 mediates repression of promoter-bound ZBRK1; and (3) how BRCA1-dependent ZBRK1 repression is regulated by DNA damage-induced cell signaling. These studies should reveal novel insight into the underlying basis for the caretaker properties of BRCA1 in preserving genomic stability and identify potential therapeutic targets for future intervention in breast cancer.
3. BRCA1 and estrogen signaling in breast cancer.
Mutational inactivation of BRCA1 confers a cumulative lifetime risk of breast and ovarian cancers. However, the underlying basis for the tissue- and gender-specific tumor suppressor properties of BRCA1 remains poorly defined. We previously discovered a novel function for BRCA1 in suppressing the ligand-independent transcriptional activity of the estrogen receptor ? (ER?), a principal determinant of the growth and differentiation of breast and ovarian tissues. Importantly, we showed that clinically validated BRCA1 missense mutations abrogate this repression activity, suggesting that its ER?-specific repression function is important for the biological activity of BRCA1 in breast tumor suppression. We hypothesize that BRCA1 represents a ligand-reversible barrier to transcriptional activation by unliganded promoter-bound ER? and, further, that mutational inactivation of BRCA1 promotes mammary epithelial cell proliferation through aberrant expression of estrogen-responsive genes. To confirm and extend this hypothesis, we are currently engaged in the following biochemical and cell biological studies pertaining to the modulation of ER? function by BRCA1: (1) the precise mechanism by which BRCA1 mediates ligand-independent ER? repression; (2) the regulation of BRCA1-mediated ER? repression by both estrogen-dependent and estrogen-independent cell signals; and (3) the biological role of BRCA1 in the control of cellular proliferation through modulation of ER? activity. These studies should reveal novel insight into the tissue-specific tumor suppressor function of BRCA1 and identify defined molecular targets for future intervention in breast cancer.
Selected Publications
Vulto-van Silfhout AT, de Vries BB, van Bon BW, Hoischen A, Ruiterkamp-Versteeg M, Gilissen C, Gao F, van Zwam M, Harteveld CL, van Essen AJ, Hamel BC, Kleefstra T, Willemsen MA, Yntema HG, van Bokhoven H, Brunner HG, Boyer TG, de Brouwer AP. Mutations in MED12 cause X-linked Ohdo syndrome. Am J Hum Genet. 2013 Mar 7;92(3):401-6.
Gu S, Boyer TG, and Naski MC: (2012) Basic helix-loop-helix transcription factor Twist1 inhibits transacivator function of master chondrogenic regulator Sox9. J Biol Chem. 287(25): 21082-92.
Spaeth JM, Kim NH, and Boyer TG: (2011) Mediator and human disease. Semin Cell Dev Biol. 22(7): 776-87.
Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, Evans RM, and Beutler B: (2011) Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proc Natl Acad Sci U S A. 108(49): 19678-82.
Xu X, Zhou H, and Boyer TG: (2011) Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signaling. EMBO Rep. 12(3): 216-22.
Trauernicht AM, Kim SJ, Kim NH, Clarke R, and Boyer TG: (2010) DBC-1 mediates endocrine resistant breast cancer cell survival. Cell Cycle. 9(6): 1218-19.
Ding N, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, and Boyer TG: (2009) MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression. J Biol Chem. 284(5): 2648-56.
Ding N, Zhou H, Esteve P-E, Chin HG, Kim S, Xu X, Joseph SM, Friez MJ, Schwartz CE, Pradhan S, and Boyer TG: (2008) Mediator links epigenetic silencing of neuronal gene expression with X-linked mental retardation. Mol Cell. 31(3): 347-59.
Trauernicht A, Kim SJ, Kim NH, and Boyer TG: (2007) Modulation of estrogen receptor alpha protein level and survival function by DBC-1. Mol Endocrinol. 21(7): 1526-36.
Zhou H, Kim S, Ishii S, and Boyer TG: (2006) Mediator modulates Gli3-dependent Sonic hedgehog signaling. Mol Cell Biol. 26(23): 8667-82.
Lu M, Chen D, Lin Z, Reierstad S, Trauernicht AM, Boyer TG, and Bulun SE: (2006) BRCA1 negatively regulates the cancer-associated aromatase promoters I.3 and II in breast adipose fibroblasts and malignant epithelial cells. J Clin Endocrinol Metab. 91(11): 4514-9.
Kim S, Xu X, Hecht A, and Boyer TG: (2006) Mediator is a transducer of Wnt/beta-catenin signaling. J Biol Chem. 281(20): 14066-75.
Tan W, Kim S, and Boyer TG: (2004) Tetrameric oligomerization mediates transcriptional repression by the BRCA1-dependent Kruppel-associated box-zinc finger protein ZBRK1. J Biol Chem. 279(53): 55153-60.
Tan W, Zheng L, Lee W-H, and Boyer TG: (2004) Functional dissection of transcription factor ZBRK1 reveals zinc fingers with dual roles in DNA-binding and BRCA1-dependent transcriptional repression. J Biol Chem. 279(8): 6576-87.
Trauernicht AM and Boyer TG: (2003) BRCA1 and estrogen signaling in breast cancer. Breast Dis. 18: 11-20.
Zhong Q, Boyer TG, Hasty P, Chen P-L, and Lee W-H: (2002) Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts. Cancer Res. 62(14): 3966-70.
Boyer TG and Lee W-H: (2002) Breast Cancer Susceptibility Genes. Science & Medicine 8: 138-149.
Lee W-H and Boyer TG: (2001) BRCA1 and BRCA2 in breast cancer. The Lancet (Supplement), 358: S5.
Zheng L, Annab LA, Afshari CA, Lee W-H, and Boyer TG: (2001) BRCA1 Mediates Ligand-Independent Transcriptional Repression of the Estrogen Receptor. Proc Natl Acad Sci U S A. 98(17): 9587-92.
Zheng L, Li S, Boyer TG, and Lee W-H: (2000) Lessons learned from BRCA1 and BRCA2. Oncogene. 19(53): 6159-75.
School of Medicine |
Department of Molecular Medicine |
Graduate School of Biomedical Sciences |
UT Health Science Center at San Antonio
Web Privacy Policy | Accessibility Policy | Links provided from Health Science Center pages to other web sites do not constitute or imply an endorsement of those sites, their content, or products and services associated with those sites.


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@ T. Rowe Price
Download Our Apps Today
Access your investments and T. Rowe Price Investor® while on the go.
T. Rowe Price Personal App for iPhone®: Simply download the app and log in using your
T. Rowe Price user name and password.
- Buy and sell mutual funds, view balances, and retrieve account history.
- Access timely T. Rowe Price Insights on current market events and conduct fund research.
T. Rowe Price Investor® Magazine App for iPad®: Read this March 2013 issue and back issues with
interactive charts and added functionality.
College Savings Plans Receive Morningstar's Highest Ranking
Morningstar's ratings of the 64 largest U.S. 529 plans are based on five factors:
• Strategy and investment process,
• Funds' investment performance,
• Manager skill,
• Administrator's stewardship practices, and
• Value compared to peers.
In Morningstar's 2012 annual review of 529 plans, the T. Rowe Price College Savings Plan, offered by the Education Trust of Alaska, and the Maryland College Investment Plan were two of only four plans to receive a "Gold" rating. For the plans rated "Gold," "Morningstar has the highest conviction in the plan's ability to serve college savers over the long term." The report also mentions T. Rowe Price's "top-notch investments" and that the plans have been industry leaders for several years running because they offer "high-quality active strategies at a reasonable price."
Plans were then assigned forward-looking ratings of "Gold," "Silver," "Bronze," "Neutral," and "Negative." 22 of the industry's smallest plans were not rated.
Please note that a 529 plan's disclosure document includes investment objectives, risks, fees, expenses, and other information that you should read and consider carefully before investing. You should compare these plans with any 529 college savings plan offered by your home state or your beneficiary's home state. Before investing, consider any state tax or other benefits that are only available for investments in the home state's plan.
It's Not Too Late to Make Your 2012 IRA Contribution
You have until April 15, 2013, to contribute up to $5,000 ($6,000 if you were age 50 or older in 2012) to an IRA for the 2012 tax year. You also can get an early start on this year's contributions. Limits for 2013 have increased.
|IRA Contribution Limits
|Tax Year
|Under Age 50
|Age 50 or Older
Direct Deposit Your 2012 Tax Refund
Consider directly depositing your 2012 tax refund into one of your T. Rowe Price mutual fund accounts. Please note that your direct deposit form must be completed with our online tool and received by T. Rowe Price prior to having your refund transmitted to your account.
T. Rowe Price Connections
T. Rowe Price Connections is an exciting digital series that explores the companies, people, and innovations that are shaping the global economy and our ongoing investment decisions. Our analysts and portfolio managers gain knowledge every day about dynamic industries that are poised to have wide-ranging effects.
Learn what they have to say.
- The African Renaissance:
With 1 billion people, rich deposits of natural resources, and rapidly improving infrastructure—and politics—Africa has become one of the world's fastest-growing economic regions.
- Genomics: The field of genomics is already shaping the way we grow plants and treat diseases. And the latest technological advances suggest that this may only be the tip of the iceberg.
- Coffee: It's about much more than taste and caffeine. It's an $80-billion-a-year global industry. And it's more interesting now than ever. Learn more about the trends that are currently defining this multifaceted industry.


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You can now filter search results with text. Example: "person: john" will search only person pages for "john".
The vicious battle between Superman and the Green Lantern Corps put a lot of innocent people in danger. One of them happens to mean a whole lot to John Constantine, and he isn't someone you want to upset, Superman.
Jason Aaron's newest book starts here! Check out this spoiler-free review!
Review and recap for this week's episode
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Aquacave appears in 37 issues.
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The SVS-5 HDD Extension Unit is a 19" rack-mount type external storage unit using an Serial ATA (SATA) interface, so that it can be installed easily in a cabinet with a DVR (Digital Video Recorder). It affords excellent space saving, because a maximum of 4 SATA HDDs may be fitted to an 1U-height chassis.
- 1U 19-inch rack case
- Data transfer speed: Up to 3.0Gbps (SATA II)
- Available SATA HDD: Up to 4 (4TB)
- Maximizes space saving and capacity relative to cost
- Expandable for more storage
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US & Worldwide Patent Pending
Indexable Inserted Broach Tools for CNC Lathe & Mill Broaching
For Keyway Broaching
Phone: 310-822-2810
No Distributors
Broach Tool Sizes
CNC Broaching Speeds/Feeds/Set-up
CNC Broaching FAQ's
In The Press
The Future of Broaching
A New Broaching Approach
Insert Broaching on a CNC Lathe
Indexable Insert Broaching Tool Technology
Last Word
Contact Us
CNC Broaching Forum
Latest Forum Posts
Razorform's Keyway Broaching tools allow CNC lathes and CNC mills to broach internal keyways rather than transfer parts to a separate broaching machine or vend out to specialty broaching service.
CNC Broaching enables you to make your part Complete In One Operation And In One Location.
Blind Hole Broaching on your CNC Machining Center
The TiN Coated, Carbide, Keyway Broaching Inserts Are Indexable And Re-grindable
Watch CNC lathe broaching
Interrupted cut in MONEL!
"We recently ran up against a tough lot of Monel sockets requiring slotting six places through a helix. The material was far harder than usual, and our usual rotary broach couldn't handle it. Because the run was short, we couldn't spend a lot on tooling. The Razor Form tool cut the nasty stuff beautifully, even through the interrupts, and got the job done with less burring and deformation. Even managed to salvage the part that the old broach broke down on. Good job! Thanks for the help."
- Karl Mech, Hydrasearch Co, Stevensville, MD.
Blind Internal Keyway Broached!
"We currently implemented a broach tool from razorform tools, it was a broach application that was not a through hole which required us to look into farming out this application. With implementing the razorform tool we were able to not only keep this operation in house, we were able to combine it to the lathe operation and also because of that we were able to add the drill and tap cross holes to make it complete in one operation which is always a cost savings if you don't have to handle the parts more than once. Centerline held real well because the bore and the broached keyway were done in the same operation."
- Monty Twingstrom
CNC Manager, K-Manufacturing, Inc., Osseo, MN
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To provide CNC Keyway Broaching tech support, and save our end-users money, we do not sell to distributors.
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There are 2 Saint Francis Employees Federal Credit Union Tulsa branch locations. The addresses are:Saint Francis Employees Federal Credit Union Tulsa
Special offer to credit union members. See your instant credit report.
Also see our daily credit union news page .
Online newspapers and TV stations serving Tulsa and Oklahoma: Muskogee Daily Phoenix & Times, USA Today, or view a national listing of newspapers.
Thinking of buying a car? See Oklahoma car dealers listed alphabetically by city.


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Posts Tagged 'iMessage'
Messages for OS X Mountain Lion Replacing iChat, You can get it NOW
OS X Mountain Lion will arrive this summer. Apple has a preview up on their website. Cool, but you know what is better? The ability to download Messages, a beta program that works with Lion, yet is an official part of OS X M...
30 of the Best iOS 5 Features (list)
Tomorrow, Apple will unveil the next iPhone, presumably the iPhone 4GS or iPhone 5. Not only will it be faster and have an upgraded camera, but it will be powered by iOS 5. Here are the top 30 new and improved features that u...


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Win "Martha's Entertaining: A Year of Celebrations" on the Ehell blog! Entries close May 11th.
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...Thursday: oatmeal (mix in a ziploc bag 2 part rolled oats, one part instant oats, pinch or more of cinamon, handful of craisins, sweetener if you like. when ready to eat, put three tablespoons in a cup, add boiling water and a little milk, cover and let it sit for about 5 minutes. yum and sooo filling)....
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We discover and build what your customers really need.
This xkcd comic makes fun of university websites by highlighting the frequent disconnect between what customers really need and what they get.
Vitamins focus on features. They make you look good, but mostly increase costs and don't help your customers.
Pain Killers focus on customers and delivering value. They increase revenue, cut costs or both.
Using our Pain Killer Program we'll develop the right solutions for your customers by asking:
Now we know who, it's time to get innovative and figure out what.
Ideas are not innovation. An innovation satisfies a real need or solves a real problem. An innovation is useful, different and better.
Being innovative takes guesses, experiments, failure, learning and switching direction quickly.
Compared to traditional business processes innovation is messy. It's no surprise that all businesses struggle to innovate.
As software engineers we're used to responding to changing requirements. To stay efficient and keep on track we apply systematic development methods.
We've taken our development experience and combined it with the latest lean startup approaches in a simple two phase Pain Killer Program.
Get started quickly and see what happens. In the battle between planning and action, action wins.
Our Pain Killer Program is based on Steve Blank's proven customer development process and tailored specifically for micro and small businesses.
Using a business model canvas we map the flow between key components of your business. Unlike traditional outdated business plans your model is a flexible guide and scorecard.
The model contains guesses about jobs your customers need done. We test these guesses and find facts.
With facts we set priorities, build a minimal solution, and invite selected customers to try it and give us feedback.
We check feedback against the model and if results look good move on to building sales. If not the model needs adjusting.
In the same way the business model sets your business direction, a sales roadmap helps find and sell to the right customers.
First you must get ready to sell. Preparation includes working out positioning, channel planning, and developing sales materials.
Now you get out of the building! Customers are out there and you need to know them.
A structured interview process validates our guesses and gives better knowledge about customers needs and ways to improve sales activities.
And just like the business model we adjust the sales roadmap as we learn.
You are now a continuous innovator, routinely applying the Pain Killer process to satisfy customers new needs.
Test on the fly: "Are customers buying?", "Is the problem fixed?". Yes, good. No, what can we do differently?
Digital AD Services (Japan) produce complex catalogs. The revision process is complex and time consuming, requiring extensive client liaison. Our solution uses HTML5, JavaScript and nifty server-side processing. Now revisions are easy and efficient.
We built Business Model Fiddle, a playground for creating and sharing business models.
Developing pain killers requires a good business relationship, generally that means:
If this sounds good send Johan an email with your Fiddle link and outline your requirement, timeframe and budget. You can expect a reply within 1 business day.
Business models enable new products and technologies and help solve entirely new customer problems.Alexander Osterwalder
The way to succeed is to double your failure rate.Tom Watson, IBM
Contact us today and we'll help you uncover and solve the problems your customers really care about!
Our solutions are fast, minimalist, and responsive so a single design works across screen sizes from mobile to desktop.
Our development principles are:
We use open-source technologies including AngularJS, HTML5, CSS, JavaScript, CouchDB, MongoDB, NodeJS, MySQL and Railo.
Keep in touch by subscribing to our occasional newsletter.
We'll only send you good web business and related technology stuff with zero spam.
Unsubscribe instantly at any time. We will not share your email address.
We've sent a verification email to you. Check your inbox and click on the link in the email to verify your address. Check the spam filter if you don't get it.
Do less than your competitors to beat them. Solve the simple problems and leave the hairy, difficult, nasty problems to the competition.Jason Fried
No matter how cool your interface is, it would be nice if there were less of it.Alan Cooper
Our guarantee is to provide practical solutions that deliver value to your business and customers.
Johan Steenkamp
Owner / Founder
Orbital is a small team of experienced web application software engineers. We know how to make the Web work in business.
We've been in business for more than 12 years. We are small, efficient, and like Getting Real.
I enjoy working at the intersection of business and technology with emphasis on business model innovation and building simple and innovative solutions to real problems.
Follow me on twitter, Google+, and occasionally tumblr.


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"The message of the movie was: no one's gonna help you, little kid…You have to save yourself."
In the Fear of Sleep* episode of This American Life, production manager Seth Lind tells how he saw Stanley Kubrick's The Shining on TV when he was six years old — the same age as Danny in the movie — and how it led to two years of nightmares:
Seth: It just made it plausible. I think it was just a really quick decision, like, "I'm that kid" — as simple as that. It's like, "oh hey look, I'm on the TV. And there's really really really terrible things happening to me and my family." And that's why it got so far under my skin… Also, there were these twin girls, who in the movie are sort of spectral characters that only Danny, the little kid can see…
Ira Glass: And they're sort of shot like Diane Arbus twins… I love how your Mom's take on this is that it's so not deeply sinister, this film.
Seth: [imitating parents] "There was a little girl. Didn't he have a friend? A playmate?" [laughs] It's not fair to expect that someone else would have the same relationship as me, feeling like I kind of lived inside of it in a really terrible way for two years…
Seth's Mother: I guess it just really shows that children have very involved inner lives that their parents might not know much about.
Ira: And why didn't you ask for help?
Seth: I didn't think that anyone could help. The message of the movie is: "no one's gonna help you, little kid…You have to save yourself."
Ira: Do you think one of the reasons you didn't ask for help was because it infected your dreams? Do you know what I mean? Like, in a way, it had gotten to a part of you where nobody can go, anyway, but you?
Seth: There's a certain point where the person who is trying to help you is going to go to sleep. And I would be left alone. Everyone sleeps alone.
*The Fear of Sleep episode is also notable for Mike Birbiglia's "Sleepwalk with Me" story — so well-told that you will be able to repeat it to your friends verbatim after just one listen.


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Northern Michigan Forum-Share Events, Travel Ideas, Photos, Videos
Time: September 20, 2014 from 8:30am to 12pm
Location: Samels Heritage Farm
Street: 8298 Skegemog Point Rd.
City/Town: Williamsburg
Website or Map: http://samelsfarm.org/
Phone: 231.313.2032
Event Type: and more
Organized By: Samels Heritage Farm
Latest Activity: Sep 11
Export to Outlook or iCal (.ics)
The objective of this program is to introduce the basic skills of blacksmithing and provide an early 1900's view of a farm blacksmith shop.
Topics to be discussed and demonstrated:
Safety; Project Planning; Fire Building; Heating Steel; Shaping Techniques; Bending Techniques; Twisting Techniques; Cutting Techniques; High Carbon Steel Heat Treating Techniques.
This is a "hands on" program and all participants go home with a hand forged item(s) that they made. Please bring safety glasses, older clothes and sensible shoes.
A donation for the class is $35; all proceeds go to the restoration and preservation of the Samels Farm by the Samels Family Heritage Society.
For more info, and to register, please email email@example.com or call 231.313.2032.
Williamsburg is on M-72, about 4 miles East of US-31, 15-20 minutes from Traverse City.


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Police responded to a shots fired call on Worthington Street around 2 a.m. on Thursday.
CBS 3 media partner Mass Live and The Republican reported that officers found live and spent ammunition, but there were no arrests, no property damage and no victims.
The shooting happened outside of Kush High End Complex, which is located between Main Street and East Columbus Avenue.
Police recovered one round each of live and spent ammunition.
The incident remains under investigation.
Copyright 2013 WSHM (Meredith Corporation). All rights reserved.


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What to do now - Diversions
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Summer 2014
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The best of summer! 100+ great gardening ideas; make a summery strawberry wreath; build an Italian-inspired garden room; colourful flowers and no-fuss perennials; extend your veggie harvest and more! more
Confused about composting?
Composting is a great way to recycle—and it's good for your plants and garden soil, too. Before making a batch of backyard compost, take this fun quiz to find out if you're a composting pro or a rank amateur.
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From the Editor
Hope Sprouts
There's room for trial and error in every garden. When I bought my house, I was ecstatic about the existence of a mature tree peony in the backyard. Then I made a mistake. I decided to move it. Despite my attempts to make the plant's transition as smooth as possible, it was wilting within a few days. I continued to care for it anyway and just when I decided to give up, I discovered some new growth. Lesson learned: Don't mess with perfection.


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Going Deep w/ Amani and Dan 9:00 PM - 12:00 AM
On Air Now.
On Air Now.
(^not Aaron Rodgers....everyone knows he's not a never-nude) So Aaron Rodgers does a fireside chat every Tuesday at 540 AM WAUK in...Read More »
This graphic, courtesy of ESPN, tells us everything we need to know about the parity of the NFL and the circuitous nature of the uni...Read More »
Unfortunately for Miami's Richie Incognito, there no longer is anything undercover about his d-bagerry. Bad dude. Plain and simp...Read More »
Well the last two Monday Night Football games have been a real peach haven't they? Didn't think it could get any worse than Fail Ma...Read More »
Well this hits the nostalgia bone pretty hard. Man I remember how awesome Monday Night Football used to be. I think I was 10 (I wa...Read More »
Gamblers on the NFL this season must be pulling out what little hair they have left. There has been very little rhyme or reason to...Read More »
Welp folks I think it's time to re-analyze just how big of a fan I am. Like I thought buying a piece of construction paper for $250...Read More »
First of all, say what you will about my chosen career, my wasted degree, my neck beard or my grasp of the English language, but do...Read More »


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Turok Devs Announce 'Pirates of the Caribbean' Open World Action-RPGThe developers behind the recent Turok title are teaming up with Disney to create a new open world action-RPG based on the Pirates of the Caribbean license.
Pirates of the Caribbean: Armada of the Damned will take place before the events of the film series, according to IGN. Players will explore the world on both land and sea, and interact with various NPCs in determining their character's moral center.
Combat will be an actiony affair, while RPG mechanics will see the player leveling up over the course of the game. The ship-to-ship combat is said to be "vastly different than any other game," and economic systems are being considered.
The game is in development for PC, Xbox 360 and PlayStation 3. No release date yet.
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Funeral Services Planned for Berta Olivarez Filut06 September 2014Read More...
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MISSION – Sharyland Independent School District School Board members approved the extension of School Superintendent Dr. Virginia Richter's contract during a special meeting this week.
A Sharyland native, Dr. Virginia Richter was hired with a three-year contract in July of 2012 after serving as an administrator with Pharr-San Juan-Alamo school district for 24 years.
Although no specifics of her contract were discussed, board members did approve extending her contract for an extra year.
Richter's contract will be discussed again, with compensation in mind, at next week's board meeting, on Feb. 26.
Richter said she is happy the board has decided to extend her contract and looks forward to serving the district.
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The Progress Times is the hometown newspaper for the local communities of Mission, Sharyland, Alton, Palmview, La Joya and surrounding areas in Western Hidalgo County. We have a staff of veteran reporters who work diligently every week to bring our readers the latest news as it affects their hometown area and people.


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Keep your home a safe haven by knowing how to avoid electricity-related accidents.
Our program features six important safety rules to follow when working around power lines. Watch our Power Line Safety video and download our poster (English/Spanish/Creole) for additional tips.
Safety around trees and power lines is very important. Before any major event or before you get the trimmer out, read these important safety guidelines.
Nuestro programa resalta seis reglas de seguridad importantes para seguir cuando se trabaja cerca del tendido eléctrico.
You don't want anything to happen to your children and neither do we. They need to know how to stay safe. Our website just for kids teaches all about the hidden dangers of electricity and more.


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Welcome to the home page of the Santa Clara County Rose Society.
Santa Clara County encompasses the area from Palo Alto to Gilroy, California (essentially
most of Silicon Valley).
We are located in USDA Zone 9.
Wondering how to apply miniature and miniflora roses in your garden landscape.
Learn from the leading American Rose Society expert, Rose Gilardi who will take you on a pictures trip visiting public
and private gardens throughout the country. Find solutions for your miniature and miniflora questions.
Rose Gilardi is a life ARS member, and a member of two local rose societies.
She was District Director for NCNH District for 6 years, a Master Rosarian, Life Horticultural Judge,
and an Accredited International Horticultural Judge. She was honored to be awarded the NCNH District Silver Honor Medal,
the Outstanding District Judges Award, and Outstanding CR Award for NCNH District.
Rose received the ARS Bronze Medal from three different societies.
She also received several
ARS Presidential Citations
over the years.
Presently she is on the AOE committee and has been on several National Committees including chairing
the ARS Prizes and Awards committee. Rose was on the faculty of several CR schools/Seminars
and have presented many lectures locally and nationally on roses and related topics.
Our meetings occur the 2nd Friday of each month (except during July and August) at the
O'Connor Medical Office Building Auditorium, 2101 Forest Avenue, San Jose - right next
to O'Connor Hospital.
Doors open at 7:00 PM, program starts at 7:30 PM. Directions
The Santa Clara County Rose Society (SCCRS) was founded in 1927, and is
affiliated with the American Rose
Society (ARS).
There are currently
approximately 200 members in the SCCRS.
Our mission is to encourage interest in the rose, to promote its cultivation,
and to disseminate information on its culture among any interested people.
Although this home page is mostly intended for residents of Santa Clara County,
we hope that people outside the county will find it useful too.
Learn more about the SCCRS's
Contact us
Copyright 1995-2014 Santa Clara County Rose Society


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Sour Apple hints at broader weakness
Wall Street looks to its tech hero to save the day. But with Apple's earnings miss, it is clearer than ever that only the Fed can give the market what it wants: More easy money.
The first two days of trading this week saw more chaos worldwide, as Asian markets were trashed on Monday and European markets punished Monday and Tuesday. The locus of the trouble was again Europe's debt markets; Italian and Spanish bonds were hammered, with yields for the former climbing to 6.3% and for the latter to 7.4%.
On Tuesday, the yield for Spain's two-year bond climbed past 5%. (Contrast that with the U.S. two-year, whose yield, at 22 basis points, is a mere rounding error.) Spain is in the process of coming completely unstuck, with its regional governments (entities similar to states in the U.S.) going bust, on top of the central government and central bank's problems.
The swagger we saw the previous week (of buying companies despite the prospect of weaker third-quarter results) was dampened rather decisively Tuesday morning when UPS (UPS) lowered its expectations for the rest of the year and lost 5%. More important, that company is a pretty good barometer for the rest of the economy, but it remains to be seen if and when Federal Reserve Chairman Ben Bernanke gets the memo (more on that later).
The trading both Monday and Tuesday saw a pattern of U.S. stocks selling off, but then rallying late in the day to trim the losses, with Tuesday's rally due in part to the hope that Apple (AAPL) might save the day when it reported its results Tuesday night.
One bad Apple
Once again, the stock market was surprisingly resilient Wednesday, given the fact that the current "greatest company in the history of the world" stumbled at beat-the-number. In fact, it more than stumbled, as sales were very disappointing. It was one of the few times in the past decade Apple has not won at that silly Wall Street game.
Apple has looked vulnerable to me since March, as I pointed out at the time (the column was reposted on April 5 as part of a site refresh; it generated a fair amount of "hate mail" in the comments section, but unfortunately those are no longer visible). Thus, Apple's results this week were not a shock, nor should they have been to regular readers.
At any rate, that should have been a double whammy that brought on selling due to Apple's weighting in the Nasdaq 100 (NDX) (as well as many exchange-traded funds), and the fact that the economies of the world are so weak that even mighty Apple couldn't make its projections.
Instead, the undertow was offset by the fact that The Wall Street Journal ran a story above the fold by Jon Hilsenrath, a regular conduit of leaks and spin from the Federal Reserve, which suggested that the Fed was more prepared to "do something" quantitative-easing oriented (e.g., bond buying or money printing) than it has been. In my opinion, the article suggested that the Fed may act at next week's meeting rather than wait for the following one, on Sept. 13.
For what it's worth, The New York Times also ran a story on the same subject. As a close observer of this sort of news, I can't recall a time when both of those papers prominently featured gossip about what the Fed might do next. Obviously, the pressure on the Fed is heating up, just as it is on the European Central Bank, but it remains to be seen if Bernanke has enough imagination to do what he is supposed to believe he should.
Their coup runneth over
The faith of those stock bulls who think the Fed has their backs has buoyed the equity market through a host of disappointing earnings reports, at least when one looks at the next couple of quarters. When I saw the Apple news, I assumed it ought to be enough to "bust the tape," which would, of course, increase the pressure on the Fed for easing. However, in perverse fashion, the Pavlovian salivation about said easing tends to keep stocks from reacting to the bad news that actually does arrive.
The question for those who are short is: "Will we get a nasty plunge in the tape before Bernanke actually panics, or will he ease before that swoon occurs?" I wish I knew the answer, but I don't, although my suspicion is that bulls will need to be tested a bit more before they get their "coup de whiskey," as the Fed boys of 1926 called it.
The reason I keep rooting for the Fed to reach deeper into its bag of tricks is because I know that it will eventually, and I would just as soon get it over with. If we are ever to have a chance of cleaning up the mess in this country, we need to completely discredit the Fed and the concept of fiat money managed by a politburo.
The sooner things get worse, the better
Getting to that juncture will precipitate quite a crisis, which will also create the pressure we need for the losers in Washington, D.C., to finally stop worrying about their own re-election and do something for the good of the country.
Unfortunately, that can happen only in a world awash in fear. Having Treasurys and the dollar under pressure due to recognition of the failed strategy of printing money is going to create the exact backdrop we need. That's getting way too far ahead of myself, of course, but we can only hope we get there as soon as possible.
At the time of publication, Bill Fleckenstein did not own or control shares of any company mentioned in this column in his personal portfolio.
" If we are ever to have a chance of cleaning up the mess in this country, we need to completely discredit the Fed and the concept of fiat money managed by a politburo."
No truer words were ever witten.
Congress, the fed and Obama are our enemies. We are going to have to revolt against them.
Great article.
We will get no handouts. Green companies will continue to get millions of our tax payer dollars, but the people that could use help will get none.
Actually I am tired of open borders that are cutting deeply into our own resources. We need someone that will close the border, now.
We have no money because we give it all away... Overseas, and to take care of the illegals coming across.
Time to stop... Take care of Americans first.
"If we are ever to have a chance of cleaning up the mess in this country, we need to completely discredit the Fed and the concept of fiat money managed by a politburo."
Thank you for writing that, Bill. 1,000 points UP in about 3 weeks without solid substantiation. Hopes and begging for stimuli are not good reasons for 200 point days. I've been reading up on the LIBOR scandal. It seems to me that Wall Street would be far more cautious about that then looking to Ben for more cash. The scandal ran mainly from 2005 to 2009, or while Phil Gramm (author of the Gramm Leach Bliley Act that gave the financial sector the right to collude) was at UBS (a major bank named in the scandal). Even Bernanke and Geithner are not free from this.
Commonsense thinks these increases are last minute grubber grabs and we have days to weeks before that major retracing occurs.
Bill it is obvious to anyone that the Federal Reserve has been dong stealth easing for some time now.
When you consider how bad the real US economy is as we have been trapped in a Death Spiral of Lost Jobs and an ever weaker and weaker economy. Our real unemployment rate is north of 25 percent. The retail sales are in a downward slump. And income has been dropping like a rock.
Add in the fact that the stock market has been losing money as unemployed or retired people have been living off their 401K pension plans and taking more money out than other 401K pension workers have been putting in and that participation in 401K plans is at an all time low.
Pretty much the Federal Reserve in a disperate move has been loaning banks money at zero percent for what like 4 years now? And the banks are using the money to keep the stock market from total collapse and lining the Wall Street banker's pockets with trillions of dollars.
The real solution to our economic woes is very clear. Use to be 30,000,000 new US jobs paying $100,000 a year would have gotten us out of the mess we are in now. As more high paying jobs have been destroyed and replaced with 1/3 the number of minimum wage jobs we will need 40,000,000 million new US jobs paying $120,000 a year to get us out of the deeper hole Bernanke in his misguilded attempts has dug for the US economy.
Pretty much we are all going to wake up one day say January 28, 2013 and have the Federal Reserve tell us that the western banking system has totally collapsed and that all our stocks and bonds and monies and house values have fallen to zero. And that the Federal government has started a distribution system of the limited resources we have left.
Pretty much will make the war time shortages during W.W.II look like booming retail times.
Of course the 1 percent super rich will not be affected by this sudden drop in wealth of all other Americans. Their wealth will increase as the government sales all assets it has to them for pennies on the thousands of dollars.
Welcome to the brave new world folks. It's going to be very different than the way we live today and it is coming soon.
Funny thing about fiat money... while normal people will slow down- the exact opposite of the intent of additional currency infusion- Inflationists will scuttle all they can to ensure what does get purchased will keep costing more. The pickled thinking process is this... the majority holders of things that are or can be liquidated (coin, cash, stocks, bonds, commodities) desire them to be worth more, so they create a catastrophe- like terminate the careers of half the workforce in the world. Some of those people move to another roles, start businesses or retire early. The others force a slowing in the economy. In order to recover, governments authorize additional currency printings and sell the issues. Those issues accrue interest. Inflationists cause the economy to continue to fail until there are several issues and plenty of interest. Then they right the economy and restore the commerce they purposely manipulated. People are happy to recover so they ignore the fact that it was manipulation that caused their woes and the fact that government now owes Inflationists- huge sums in principal and interest. These people still own what they hoarded, plus get the payments in the new economy. It's literally... a financial vampire cultivating a farm of bodies to drink dry when desired!
I do not recognize Bernanke, the Federal Reserve or Quantitative Easing. There was $50-60 Trillion in currencies worldwide just 15 years ago. That is what we must return to and tie it to a valuable and useful Index. Unfortunately, those in power want to make a World Currency, not because it is better for us, but easier to manipulate. Divest global... Close the banks. Save the world.
bottom line: Cut off their revenue and ramp up their expenditures until they collapse.
The country dwellers will find a way to live on without bloated government. When the urban entitlement class, gangs, and other human filth comes crawling out for food, they can work on your farm.
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Fundamental company data and historical chart data provided by Morningstar Inc. Real-time index quotes and delayed quotes supplied by Morningstar Inc. Quotes delayed by up to 15 minutes, except where indicated otherwise. Fund summary, fund performance and dividend data provided by Morningstar Inc. Analyst recommendations provided by Zacks Investment Research. StockScouter data provided by Verus Analytics. IPO data provided by Hoover's Inc. Index membership data provided by Morningstar Inc.
This column is a synopsis of Bill Fleckenstein's daily column on his website, FleckensteinCapital.com, which he's been writing on the Internet since 1996. Click here to find Fleckenstein's most recent articles.
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[BRIEFING.COM] Equity indices remain near their flat lines as heavily-weighted sectors continue trading in mixed fashion.
At this juncture, the industrial sector (-0.6%) is the weakest performer among cyclical groups with defense contractors pressuring the space. The PHLX Defense Index is lower by 1.1% with just about every component trading lower. Including today's decline, the Defense Index is now down 2.4% for the week and off 0.7% so far in September. On the upside, General ... More
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As the devil-may-care bravado of Wall Street marches on, history warns that -- in the end -- there will be the devil to pay.
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