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I had higher hopes for the feel of the fabric after reading another review. Make no mistake, the fabric is quite nice, but I was hoping for a silkier and more polished feel. I would describe the weight as "medium." These made-in-India sheets came out of the washer/dryer looking very nice and nearly wrinkle free, but the fabric has a "nap" that I'm not crazy for. This nap is going to grab flannel and cotton bed clothes and hang on tight enough for a serious "nightgown twist" or "pajama wedgie." Maybe this nap will lessen after repeated laundering - I certainly hope so. I ordered "taupe" which is nearly as dark brown as dark chocolate. None of these things are a big enough issue for me to return the sheets, but it's still a bit disappointing and I wouldn't buy them again.
Bought these sheets in sage and think they are great. The color is what I expected. The material quality exceeded my expectations. I have the 8" Serta memory foam mattress that I bought from this site. I also have a 2" memory foam topper that I put on it. WIth the mattress and topper combined the sheets fit very well. They fit the corners very nice and they don't feel like they are about to rip as some others have. Fitted sheet fits the matress surface and corners tightly. Flat sheet is long enough to tuck deep under the footboard end of the mattress and still pull all of the way up to the top edge near the headboard. After 1st wash they were still a little too rough. After 2nd washing they had just a hint of newness / roughness. After 3rd wash they were comfortable. After 4th wash they are perfect. Definitely some of the most comfortable sheets I have slept on anywhere....ever! I don't think I would consider sheets with a lower thread count than these, especially for the insignificant difference in price compared to the several years of use that I will get out of them. Have no fear of these sheets after a few washes. Anyone that would complain about the comfortability of these sheets after washing out the newness probably has a life-long predisposition towards complaining about everything in life... those people annoy me.
I bought these sheets to replace a set of 600 TC sheets that I bought in Egypt six years ago that had worn out. I was sceptical about them living up to the quality of the ones they were replacing but they definitely have! They have only been washed about three times but even after the first wash they had softened up and are very comfortable and they have not pilled at all. I will definitely be buying some more of them.
After purchasing a cheap 200 TC set of sheets from ***, I knew I needed something much softer. I did some research about thread counts, materials, etc., & decided to order these. I was very disappointed to discover that these didn't feel any more comfortable than the cheap set from ***. While the material is heavier, they feel stiff & coarse, even after washing. I ended up purchasing a different brand w/ a 400 TC from *** for half the price, which are far more comfortable! If I were you, I'd save your money & shop elsewhere.
When I opened the package, I thought at first they had shipped the wrong color, but they didn't. I ordered 'taupe' and got that, but they really aren't. Beware, their taupe is "milk chocolate" brown. The cotton is a high quality, but they aren't soft. If you care about wrinkles (I don't) then don't buy these sheets. They wrinkle badly. All that said, I'm not returning them because they will soften and the cotton is a high quality. If you wan't a soft sheet to begin with, buy Sateen sheets.
I was looking forward to the arrival of these sheets as they were a gift for my mother. The color is point on and beautiful, I bought the cranberry color, but the sheets are very stiff and heavy, not at all what I expected especially with the high thread count. I washed them before use and they were still very stiff. I would not recommend if you are expecting soft sheets. In the past I have had great luck in purchasing bedding from Overstock, but I have to say this time I was very disappointed. I'm hoping with multiple washes they will soften.
I ordered to different colors in these sheets and the are just beautiful and very comfortable. The colors are amazing and they are so so soft.
Smooth and comfy sheets with good amount of fabric for deep pockets in the corners.
When I washed the sheets upon arrival they were buttery soft and I loved them. After the third washing the sheets started pilling, no longer buttery soft but rough. I'm very disappointed that these sheets did not retain their initial feel and indeed were rougher than my cheap sheets. I have had other high thread count sheets that did not pill even after years of washings. I would not recommend these sheets.
I'm thrilled with these sheets. The color (gold) is exactly what I wanted, the quality is excellent, the price was good and they're not slippery like a sateen weave. I've only washed them once, which they survived just fine. The feeling is more crisp and substantial rather than super-soft or smooth, which is exactly what I like. Best of all, I actually feel like I sleep better in them.
Usually leaves our warehouse in 1-2 business days. *
Items must be returned in new or unused condition and contain all original materials included with the shipment. More details
FINAL SALE EXCLUSION: Items marked as FINAL SALE are not returnable unless the problem you experience is the result of our error.
Our standard shipping method is ground shipping. We also offer expedited shipping for most items. Your final shipping cost and estimated delivery timeframe will be available at checkout.
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Expedited shipping details
* For your safety, some orders go through our loss prevention department. If we select your order for this process, we will immediately notify you that there may be up to a 3-day delay on your order.
** Most Oversize orders are delivered within 1-4 weeks. Some orders may take 6 weeks to be delivered.


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Outdoor Cookware
- Pizza Que Grill Stone
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Outdoor Cookware
Outdoor cooking is simple and enjoyable with our outdoor cookware. Our collection of BBQ tools include grills, smoker wood chips and meat thermometers. Find food for grilling and get inspired for your next outdoor gathering and grill up fish, pizzas or chicken using our outdoor cookware for perfect grilling every time.

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Don't leave it alone with your pets.
Share your thoughts
What do you think of the
Spacecraft The Good Beanie
? Share a...
The Good Beanie
Jesse Thunderbird
Member since
Member since
This beanie was not at all what I expected. First of all it was extremely big, even if you do have an abnormally large head. Secondly the color was a lot different than the picture showed and I even googled it to make sure the color was what I was looking for. Overall I was very unhappy with the product and would not recommend buying it.
Aimee Koson
Member since
This hat is so cute, it looks big but once its on it fits great with a little baggy back to set the look. The interior has a thin almost t-shirt cotton material as the liner. I love it!
what material is this hat made of? Cotton,...
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what material is this hat made of? Cotton, wool, nylon?
Arthur Debowski
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These are made of acrylic.
Slouchy and soft!
Member since
Slouchy, soft, and simple logoing.


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The Canadian World Junior squad will step on the ice for their second of three exhibition games on Sunday but will have a slightly different line-up.
(Catch the action on TSN2, Sunday at 7pm et/4pm pt)
Canada defeated Sweden 4-2 in its first exhibition game on Friday. The Canadians looked strong in the win but it came at a cost as Dana Tyrell went down to injury.
Tyrell, of the WHL's Prince George Cougars, suffered a knee injury and was lost to Canada for the rest of the tournament. As a result, Vancouver Giants' Evander Kane will join the team.
Kane is expected to arrive at the airport today at 4pm et andshould dress for the game, but head coach Pat Quinn has not committed to playing the forward against Finland.
The 17-year-old Kane is sixth in the WHL in scoring with 22 goals and 26 assists over 28 games this season.
Kane was a member of Canada's gold medal winning under-18 team at the 2008 Memorial of Ivan Hlinka tournament this past August.
Canada will be facing a Finland team headed by centre Niklas Lucenius and defenceman Jyri Niemi.
Lucenius was drafted by the Atlanta Thrashers in the fourth round of the 2007 NHL Entry Draft and had six points over six games in the World Junior Championship a year ago.
Niemi plays for the Saskatoon Blades in the WHL and was a third round pick of the New York Islanders in 2008.
Finland 3, Sweden 2 (OT)
Russia 2, Canada 1
Tournament Recap | Group Standings
Game-By-Game Results


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Having a baby is said to be one of most life changing, amazing experiences you'll ever have. But for many moms who give birth via C-Section that experience was anything but amazing. Nancy Naeve Brown went to Aberdeen to show how Avera St. Luke's implemented a new program to change that.
Caroline Homan of LaMoure, North Dakota is a new mom to her second child 2 month old Ellery Claire Narum. She delivered both her children via C-Section here at Avera St. Luke's in Aberdeen, but the delivery experience between the two was very different. When Asher was born 2 years ago, she says it left her feeling alone, because she was alone.
Caroline says, "After the baby was born they took him and wrapped him up and I saw him for about 5 seconds. My husband brought him over, it wasn't really 5 seconds but it felt like it. They held him by so I saw his little head and then they left. I was taken to recovery for 2 hours and he went upstairs to our room. It was a really lonely sad experience."
The team at the Birthplace knew they had to change that. A year ago they started the "First Touch" program for C-Section moms and their babies in conjunction with their new same day surgery wing using the private post anesthesia suites.
Avera St. Luke's OB/GYN Dr. Gregg Carlson says, "We have a dedicated area with an isolette where the mom comes into the recovery room for another half hour to 45 minutes and the baby is right there with them."
Caroline says, "With Ellery they cleaned her off and did the initial tests right beside me so even when I was on the operating table I could look over and see her and I saw her skin turn bright pink. The nurses were telling me what they were doing and they were taking care of her. I felt I was part of it instead of disconnected."
Before the new program was implemented, the mom would be in the O.R. and then go directly to recovery. She wouldn't have any significant time with her baby for at least two hours.
Caroline says, "In the recovery room they laid her on my chest and she immediately started nursing. I never got to do that with Asher."
Dr. Carlson says, "The bonding in a big deal. A really big deal because it's as if they were missing a portion of their labor experience. What everyone looks forward to is seeing their baby, touching their baby and hearing their baby cry and snuggling it. People felt they were missing something."
Avera St. Luke's doesn't want any new mom to miss out on one minute of the miracle of birth which now also includes the moms who had to withstand surgery in order to give life to that miracle.
Caroline says, "It made such a difference."
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Posts tagged "wallets"
Holiday Wishlist: Erika
For our 3rd round of employee wishlists, we've got Erika, one of the most cheerful faces around the office! Read on for all her picks.
Joyrich x LeSportsac Bags are Finally Here!
After months of anticipation, the Joyrich x LeSportsac collaboration collection is finally available for purchase on Karmaloop!
Runway Inspired
If Safari's not your thing and you'd much rather turn heads in a crowded room, our RUNWAY INSPIRED Shop by Style category might be more up your alley. Lux items from our favorite runway shows don't usually get along well with our wallets, but trends always transcend the limits of our bank accounts! I recently...
Discounts On Deck!
The transition from Winter to Spring and Summer is the most exciting time to give your wardrobe an exciting makeover. However doing so can often break the bank! Check these awesome pieces now on sale for your wardrobes, and wallets convenience. Left: The Villains Motorcycle Jacket in Steel Gray by Hellz Bellz, $77.95 (was $172)...


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Cardinal Gates® 10 1/2" Side Extension for Auto - lock Pet Gate
Item # WX2-166363
- Google+
This item is shipped directly from the factory. To see the expected shipping date, please add to your Shopping Cart. Sorry, no express shipping available. We are unable to ship factory direct items to Alaska, Hawaii, Puerto Rico or APO or FPO addresses.
This item cannot ship to Canada.
This item cannot ship internationally.
- Details & Specs
Cardinal Gates® 10 1/2" Side Extension for Auto - lock Pet Gate. SAVE BIG!
Just add one of these handy Side Extensions: 10 1/2" Side Extension, expands the Gate to fit openings 40-50 1/2".
State Color, as available in the Shopping Cart. Order ONLINE Today!
- Reviews
Customer ReviewsNo reviews exist for this item....
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Expandable Metal Pet Gate with DoorBuyer's Club $29.99 Non-Members $29.99
Expandable Wooden Pet GateBuyer's Club $26.99 Non-Members $29.99
AKC Pet BarrierBuyer's Club $16.19 Non-Members $17.99


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Kolpin® ATV Works Box
Item # WX2-172732
- Google+
This item cannot ship to Canada.
This item cannot ship internationally.
- Details & Specs
Kolpin® ATV Works Box. A big, smart hauler!
This Kolpin® Works Utility Box is the only ATV hard box designed to securely transport two 5 gallon buckets and the Kolpin Fuel Pack Jr., or additional gear. Great for hauling gear whether hunting, ice fishing, landscaping or just doing the trails.
- Molded design can cradle a pair of 5 gallon buckets, plus the Kolpin Fuel Pack Jr. (not included) securely. Or other sizable mixes of gear
- Removable, snap-close lid is strong and protective
- Mounting hardware included to fit on just about any ATV
- Measures 30" wide, 8 1/2" high.
Get the right ATV gear space at the right price!
- Reviews
Customer ReviewsNo reviews exist for this item....
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Don't Forget
4 Smart Strap 3,000 - lb. 10' Ratchet Tie DownsBuyer's Club $22.49 Non-Members $24.99
12-Pk. of 900-lb. Smart Value Ratchet StrapsBuyer's Club $26.99 Non-Members $29.99
Kolpin® Rhino Grip XL ATV Gear ClampsBuyer's Club $26.99 Non-Members $29.99
You May Also Like
Kolpin® Rear Trail BoxBuyer's Club $134.99 Non-Members $149.99
Kolpin® Front Trail BoxBuyer's Club $116.99 Non-Members $129.99
Raider® Deluxe ATV Front BoxBuyer's Club $143.99 Non-Members $159.99


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This Industry's Best Value
Chad is a member of The Motley Fool Blog Network -- entries represent the personal opinion of the blogger and are not formally edited.
I know that some investors are willing to buy multiple stocks from the same industry if they find each of the companies attractive. However, I fall into the camp that I want diversification, but I would rather choose the very best of an industry and put my money into that one stock. Brokerage and investment companies seem like good opportunities since they benefit from the need to grow wealth over time. Since very few people can grow their assets without investing in stocks or bonds, in theory these companies should do well over time. Looking at the different options, it seems like T. Rowe Price (NASDAQ: TROW) could be the best value at the current time.
In the brokerage and investment company businesses, there used to be a divide between companies offering full-service advice and management, and discount brokers. However, over the last few years the line has been blurred between discount brokers, mutual fund companies, and investment managers. Through natural expansion each of these types of companies is attempting to broaden their offerings. This puts companies like The Charles Schwab Company (NYSE: SCHW) and Franklin Resources (NYSE: BEN) in direct competition with T. Rowe Price and others. The difference between these two companies and T. Rowe seems to be T. Rowe has better organic growth, and analysts are expecting faster growth for the company in the future as well.
Given that I live in Maryland, some might say I'm just touting the home team by talking about T. Rowe, but I don't let the location of companies determine whether they are good investments, I let the numbers speak for themselves. Looking at the company's recent quarterly results, T. Rowe is making its case as the best investment management stock no matter where they are located. The company saw revenue increase 13.29% and EPS increased by 32.39%. In addition, T. Rowe showed significant organic growth, with average assets under management up 14%, and this growth was split evenly between stock and bond funds. The company is heavily weighted toward stock and blended asset funds with over 74% of assets in these types of investments. With investors increasing their stock and blended asset exposure by 16% on a year-over-year basis, it appears T. Rowe investors are anticipating better times ahead for the market. Though bond and money market funds sport yields that are historically very low, this asset class saw account growth of 13% itself. It's not hard to understand that investors are attracted to T. Rowe funds. Seventy-six percent of the company's fund classes have outperformed their averages over the last 1, 3, 5, and 10 year periods. T. Rowe's top and bottom line growth is impressive, but their financials tell an even better story.
T. Rowe earnings growth is impressive, but I also want to see that this earnings growth contributes to free cash flow as well. The good news for investors is T. Rowe is very successful in converting its sales and earnings into cash flow. In fact, if you compare the company to its peers, T. Rowe reports a very good sales to free cash flow conversion rate. When comparing free cash flow across different size companies I use free cash flow per $1 sales. This ratio allows investors to compare how effective companies are in turning $1 of sales into free cash flow. The leader in this category is Charles Schwab, which generated almost $0.48 of free cash flow for each $1 of sales. Schwab serves a higher-end clientele base and has more managed accounts than T. Rowe, so this lead isn't too surprising. That being said, T. Rowe generated about $0.29 of free cash flow per $1 of sales over the last nine months. By comparison, Franklin Resources only generated about $0.09 of free cash flow using this same measure. Given that T. Rowe operates more of a standard mutual fund business, the huge difference in free cash flow versus Franklin Resources is amazing.
T. Rowe also is improving its margins, with the company's operating margin increasing from 43.34% last year, to 46.63% this year. This higher margin allowed the company to generate almost 12% more operating cash flow over the last several months. In addition, T. Rowe has increased its cash and cash equivalents by 37.54% during this same timeframe. This shows that the company understands how to make the most of its cash flow by rewarding investors with its dividend, and shoring up the balance sheet at the same time.
When it comes right down to it, T. Rowe looks like a buy based on its growth potential and income generation versus its peers. Charles Schwab is expected to grow earnings in the next few years by 7.7% and Franklin is supposed to grow by 10% over the same timeframe. By comparison, T. Rowe is expected to grow earnings by over 13%. When it comes to income, T. Rowe also beats its competition by offering investors a nearly 2.1% yield versus 1.75% at Schwab and just 0.9% at Franklin. With the highest expectation for earnings growth and the highest yield, you would expect the stock to also carry the highest P/E ratio, but it does not. In fact, Schwab sells for nearly 19 times forward estimates versus about 17 times estimates at T. Rowe. While Franklin is cheaper at about 12 times estimates, the company's slower growth rate, lower yield, and much lower free cash flow makes this a difficult comparison to T. Rowe. If the economy continues to improve, the stock market should do well. Since T. Rowe has nearly three-quarters of its assets in stock and blended assets, the company would benefit tremendously by increased investment in stocks. The company has good organic growth, the best yield of the group, and the highest expected earnings growth as well. This sounds like the best value in its industry to me.
MHenage has no positions in the stocks mentioned above. The Motley Fool has no positions in the stocks mentioned above. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy. Is this post wrong? Click here. Think you can do better? Join us and write your own!


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Definition of reeded in English:
reededSyllabification: reed·ed
Pronunciation: /ˈrēdid /
1Shaped into or decorated with semicylindrical adjacent moldings.
More example sentences
- Whistler, taking his cue from the English Pre-Raphaelites, experimented with reeded moldings and with various shades of gold leaf.
- Nonetheless this interpretation of the classical style was born deep within the backcountry despite the impressive reeded legs, half-spindles, and drawer with a convex front.
- The reeded footposts with undercut foliage are typical of Salem beds of the Federal period, but the dramatic canted, carved paw feet move the bed into the classical style.
Definition of reeded in:
- The British & World English dictionary
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Word of the day fioritura
Pronunciation: fēˌôriˈto͝orə
an embellishment of a melody...


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Citizens Police Review Board To Discuss Larimer Shooting, South Side Chase
Pittsburgh's Independent Citizen Police Review Board is set to meet this evening. They are expected to discuss two recent incidents involving police officers' actions that are being reviewed; KDKA's David Highfield reports.
Energized Pirates' Fans Hoping For Spot...KDKA-TV Nightly Forecast (9/20)Tense Manhunt Continues In Northeastern...Carrick Residents Upset After KKK Signs...Devastating Fire Leaves Oakmont Church...Local Jack Russell Terrier Ends Up In...Apple's New Operating System May...Woman Jailed After Going On Wild RampageAlligator May Be Lurking Along Allegheny...Man Accused In Mother's Death In...Man Charged With Sending Lewd PhotosOakmont Church A Total Loss After FireForgotten Treasures Up For Sale At...People Wait In Long Lines To Get New...New Hazelwood Development A Missing...Still No Confirmation On Possible EV-D68...Jeannette Woman Attacks 3 Neighbors,...Family Friend Accused Of Sexually...Fire Destroys Oakmont ChurchRAW VIDEO: Oakmont Church Fire (Pt. 3)


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What Was Miley Cyrus' Favorite Part Of Being Engaged?
20 Super Awkward Celebrities
Famous and Faithful - 10 Most Successful Partnerships
16 Celebrities With Royal Blood
Celebrities Who Have Aged the Worst
Lupita Nyong'o Is Finally Sharing Her Beauty Tips
57 and 18! The Creepiest Celebrity Couple Ever
These Celebrities' Natural Hair Colors May Surprise You
14 Celebrity Moms Who Breastfeed in Public
Nicki Minaj's Butt Implants Burst On Stage! Shocking Photos
The 8 Richest Celebrity Families
The Hottest Pictures of Old Celebrities When They Were Young
Plastic Surgery Scar Spotted on Kylie Jenner's Face
7 Celebrities Who Look Better After Having Babies
The Plastic Surgery That Changed Lisa Kudrow's Life
Kylie Jenners $1 Million Plastic Surgery Shocker
7 Celebrities Who Are Scary Hairy
11 Hottest Celebrity Dads
13 Celebrities Who've Gone Completely Crazy
Where Will George and Amal Honeymoon?
Sandra Bullock Opens Up About Chris Evans
They're Just Like Us: 13 Humiliating Celeb Photos
Inside Kim and Kanye's $20 Million Mega Mansion
13 Stars Who Were Turned Down By Playboy
11 Celebrities Who Are Aging Backwards
Proof That Kanye Always Had a Crush on Kim
Mariah Carey's Twins Are Incredibly Adorable
12 Beautiful Stars That Look WAY Different Without Makeup
A New Site Exposes Everyone's Past. What Can You Uncover?
Kim's Latest Face Lift Has Made Her Unrecognizable


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Time for some All That Remains again, this song has been played frequently on my Spotify lately, one of the best songs from their latest album!
All That Remains was formed by Phil Labonte in 1998 and was originally a side-project of his. After leaving the melodic death metal band Shadow Fall he decided to focus on All That Remains and they released their first album in 2002. Since then they've released five more albums, the latest being A War You Cannot Win. The group consists of Phil Labonte (Vocals), Oli Herbert (Guitar), Mike Martin (Guitar), Jeanne Sagan (Bass) and Jason Costa (Drums). A War You Cannot Win was released in 2012 and was produced by Killswitch Engage guitarist Adam Dutkiewicz.
The seventh song of the album is Just Moments In Time, which is a hard and heavy song that has one hell of a nice breakdown. Phil Labonte uses both growls and cleans on this one, and the breakdown is really sweet with the fast-hitting drums. A War You Cannot Win has incorporated more heavy metal elements than their earlier albums, and has a nice variety, containing singing styles ranging from growls to loads of clean parts. It's a damn good song and I'm looking forward to seeing them again at Metaltown in the summer!
YouTube: All That Remains - Just Moments In Time
Check my blog for more music and album reviews! Do you have any questions/requests? Ask on Tumblr or on Twitter -> SebastianLovas
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Baking and Pastry Instructors
Belinda Brooks
Baking and Pastry Chef Instructor
Belinda Brooks teaches baking and pastries to Kendall students, giving them a survey of a variety of pastry applications. She launched her career in front- and back-of-house positions with both Aramark and Sodexho Marriott. Brooks then decided that baking and pastry was her true love and left to study at the Culinary Institute of America in Hyde Park, NY. Since graduating, she has worked with Spago's catering division and the Standard Club, both in Chicago.
Brooks is a graduate of Roosevelt University in Chicago with a degree in Hospitality Management.
Heidi Hedeker, M.A., C.E.P.C.
Baking and Pastry Chef Instructor
Students who dream of operating their own bakeries will certainly find Heidi Hedeker an invaluable resource. She grew up in the business, working in her family's bakery on the Northwest side, Gladstone Park Bakery. Hedeker went on to own her own shop in Wicker Park, Alliance Bakery, chosen as Best Retailer of the Year by Culinaria in 2000. She also owns SweetChef.net, an online bakery specializing in European pastry. In addition, Hedeker is a consulting baker for The Good Loaf, an organic, not-for-profit bakery.
Along with hands-on experience, Hedeker is a food writer with a Bachelor of Arts degree in writing who was an editor at Baking Magazine.
Melina Kelson-Podolsky, C.M.B., C.E.P.C.
Baking and Pastry Chef Instructor
We are pleased to have Melina Kelson-Podolsky, a Certified Master Baker, on staff at Kendall College. She sits on the board directors of the Bread Baker's Guild and on the Advisory Board for Growing Power. She is an active member of Les Dames d'Escoffier. She has traveled the world and speaks Hebrew, Italian and Spanish. Kelson-Podolsky has also broadened her culinary skills by working in both sweet and savory positions with caterers, bakeries patisseries and restaurants including James Beard Award-winning Spiaggia and Brasserie T.
Kelson-Podolsky holds a Bachelor of Arts degree in English Literature from Ithaca, plus a Pastry Certificate from Cooking and Hospitality Institute of Chicago. She taught at CHIC for four years before coming to Kendall College.
Mark Kwasigroch
Baking and Pastry Chef Instructor
As a teenager, Mark Kwasigroch got his start by washing dishes at the Gladstone Park Bakery on Chicago's northwest side. There, he learned the basics of the craft and moved on to work for The Little French Pastry Shop, major hotels, Reuters Bakery and the Tel Aviv Bakery, where he learned the art of kosher baking.
Kwasigroch's love for baking brought him to Michel's French Pastry Shop. Chef/Owner Michel Tournier provided further training and later sold him the Winnetka Patisserie. While creating pastry for North Shore events, Kwasigroch was twice featured on NBC's The Today Show. His industry experience also includes technical baking consulting and sales management for bakery products companies.
Siddharth Mangalore, M.B.A., C.E.P.C.
Baking and Pastry Chef Instructor
After completing his studies in the field of Culinary Arts from Mumbai, India, Siddharth Mangalore worked for a decade in some of the finer pastry kitchens around the world and in Chicago, such as The Peninsula Hotel and The Chicago Yacht Club. His quest for continuing education has since continued under various master pastry chefs such as Ewald Notter and Ralph Gottschalk.
Along with teaching the art and skill to a new generation of pastry chefs, Mangalore's prior experience as a Career Services Counselor allows him to counsel and guide students in making the right internship and career choices.
Erika Webb, C.E.P.C.
Baking and Pastry Chef Instructor
Erika Webb began her culinary journey following an inspirational cross continent tour of Europe during the early '90's. Sensing a deepening interest in the pastry arts, she pursued training at the Ritz Carlton Hotel, Chicago, under the leadership of pastry chef En Ming Hsu. She's also worked at other notable Chicago restaurants, namely Charlie Trotters and Tru. An interest in specialty baking led her to Royale Icing, Inc. where she gained skills in cake decorating and gumpaste techniques.
Chef Webb holds a B.A. in International Ministries from Moody Bible Institute, an A.A.S. in Culinary Arts from Triton College, and a certificate in Chocolate Showpieces and Candies from the French Pastry School.


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Sure, many women admit they occasionally come up with excuses to get out of having sex. But there are also often legitimate reasons why they don't want to get it on. And while we're at it, let's clear up an ugly little gender myth here ... Women aren't the only ones saying "no" to sexytimes. Men are just as guilty of making excuses! And, believe it or not, also have their reasons for abstaining.
Here, 20 actual reasons a guy may say "no" to a bedtime romp ...
What are some other real reasons your man passes on sex?
My balls hurt.


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Ph.D. Program
In the Smeal College of Business at Penn State, we believe that doctoral education is at the very heart of our mission. Our students specialize in one of six primary fields: accounting, finance, management and organization, marketing, real estate, and supply chain and information systems.
During the doctoral program, you'll focus intensively on learning how to do research, reading research articles, collaborating with professors on research projects, and embarking on your own research career.
The Ph.D. is for students who want an academic research career. The Ph.D. degree is not for part-time students. It is not a "turbo-charged M.B.A.," nor is it designed for people pursuing careers as consultants or managers.
We believe that good researchers make good teachers. People who are at the leading edge of knowledge development are the ones who bring excitement and learning into the classroom. Thus, in developing your skills as a world-class researcher, you will also be developing your ability to contribute to the education of others.


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Not against Mars mission..never,but against economists..
Courtesy NASA/Goddard
Published October 29, 2013
NASA's next Mars mission aims to uncover the red planet's ancient atmosphere. The Mars Atmosphere and Volatile Evolution Mission, or MAVEN, will launch on November 18, weather permitting, for a ten-month trip to Mars.
Here are five things to know about the $671 million mission to the planet that most looks like Earth, and that some hope still harbors life:
1. MAVEN is an orbiter, not a rover.
The space agency has two rovers, Opportunity and Curiosity, rolling on the red planet right now. MAVEN will instead circle the planet some 106 miles (170 kilometers) above the Martian surface.
High above the red planet, MAVEN will turn its instruments to the planet's upper atmosphere. The goal is to see how quickly the sun's solar wind strips water and carbon dioxide away from the planet.
Over a Martian year, the team hopes to see the effects of solar storms and the solar wind upon the atmosphere, says mission chief scientist Bruce Jakosky of the University of Colorado, Boulder.
2. Mars once had a warm and wet atmosphere.
MAVEN's mission is to rediscover what atmospheric conditions once allowed the existence of the lakes, rivers, and seas that left their traces left on the Martian surface. They are thought to date from several billion years ago.
NASA's Curiosity rover, for example, last year reported evidence that it had landed in an ancient riverbed inside Gale Crater on Mars, where water once ran waist-high.
"It's clear there are many questions about Mars that center on the history of its atmosphere," Jakosky says. For example, what exactly happened to the thicker, carbon dioxide-rich atmosphere that once sheltered those lakes and rivers?
3. The spacecraft won't find Martians.
A lot of the hopes about microbes living under the Martian surface rode on reports that methane gas was surprisingly common in the planet's atmosphere. But MAVEN won't be looking for methane.
It might be just as well; recent Curiosity rover surface readings have cast doubt on the methane findings. (See "NASA Rover Dims Hopes for Martian Methane".)
To keep the mission focused and costs down, Jakosky said the spacecraft will concentrate instead on carbon dioxide and water vapor, the two most important gases for understanding the atmosphere's past.
Photograph by John Raoux, AP
Mars's atmosphere is very thin, less than one percent of the thickness of Earth's at sea level. And its chief gas is carbon dioxide, which is about 95 percent of the red planet's atmosphere. Carbon dioxide is a greenhouse gas, and when it was thick on Mars it likely provided an insulation blanket that helped maintain those long-vanished rivers and seas.
4. MAVEN will carry Earthlings' names to Mars.
Pinned to one of the spacecraft's solar panels is a DVD with the names of a hundred thousand Mars fans, as well as an elementary school's class project, the winner of a Mars travel contest. The kids told NASA what they would like to take to Mars someday.
The DVD will also carry contest-winning haiku written by folks interested in the mission. Here's one winner from Greg Pruett, a U.S. contestant:
distant red planet
the dreams of earth beings flow
we will someday roam
The space agency received 12,530 haiku entries in the contest. Who says poetry is dead?
5. The orbiter will keep other Mars spacecraft going.
One reason that NASA deemed the launch of the spacecraft essential during the recent U.S. government shutdown is that it will serve as a long-lived communications relay for rovers and other spacecraft orbiting Mars. NASA plans to send another rover like Curiosity to the red planet in 2020.
(Related: "NASA: Shutdown Won't Stop MAVEN Launch.")
Spending the money to send the MAVEN orbiter to Mars is a sign of the space agency's commitment to Mars exploration, said NASA science chief John Grunsfeld, speaking at a briefing on the mission on October 28.
Whatever the mission finds, it will likely be interesting, he added, endorsing the slow and steady investigation of the red planet championed by the space agency over the last two decades.
"No other planet, other than perhaps Earth, has served as inspiration for legions of science fiction writers," Grunsfeld said. "And for scientists who thought they were doing science but were actually doing science fiction."
Follow Dan Vergano on Twitter.
Converting earth into mars...we are exploring mars
Mars is what are earth will look like in 5 million years. When we have the technology to explore its surface more deeply ,its secrets of past life forms will be revealed and our view on religion will be changed forever.
Jesus once said: 'The house of my Father has many rooms.'
Hey, Elvis,
I believe the Bible too, but it never even spoke of Mars, much less any life "out there." It can't address everything. The Bible addresses life's issues not scientific exploration. I hope to live to see the day when we can confirm the existence of life beyond our tiny "blue dot." Creation is much bigger and much greater than any single book or person can ever imagine. We need MAVEN and Opportunity and Curiosity to open our minds.
This sound interesting but the Bible which i believe in never told me that life exist in any other plannet except the Earth.
@Elvis Nmehielle It also did not say that life didn't exist elsewhere.
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Paul Cully
Wallabies mustn't ignore young bulls
Paul Cully Remember the name of Bulls inside-centre Jan Serfontein. The outstanding young midfielder - big, strong, fast but with skills and vision- has the ability to change the way the Bulls attack and be a...
Bulls play the percentages but don't expect much flair
Paul Cully Placed alongside some flashier examples of the modern age, Bulls five-eighth Morne Steyn cuts an unprepossessing figure. But take a second look.
Misfiring Wallabies keep tossing up more questions than answers
Paul Cully There were question marks even after the win against South Africa, and they remain after Argentina.
Tight Five
Reds highlight Waratahs' lineout problems in the nick of time
Paul Cully Against a side with a lesser defensive lineout than the Reds, the Waratahs could have headed into the finals with paper over the cracks, but their lineout problems on Saturday night will sharpen the...
Tight Five
Waratahs hit first big hurdle with Dave Dennis injury
Paul Cully Dennis may not be a highlight reels man, but he gives the Waratahs such great balance.
Quade Cooper draws down credit with poor second half for Reds against Hurricanes
Paul Cully When you play as well as Quade Cooper did on the end of season tour last year, you put a fair bit of capital in the bank.
Super Rugby stats don't back up Australia's running game
Paul Cully Australian rugby's relationship with a running, ball-in-hand style of play is going through a complicated patch.
Wallabies are still the Bledisloe underdogs and should embrace it
Paul Cully Optimistic thinking about a shift in the Bledisloe Cup balance of power has undergone a correction over the past two weeks in Super Rugby, and it is not necessarily a bad thing for the Wallabies.
Western Force no-names the bolters for Wallabies
Paul Cully Matt Hodgson should be leading a merry quintet of Western Force players into the Wallabies' first squad of the season when it is announced next week.
Tight Five
Waratahs' season continues to blossom into greatness
Paul Cully How well are the Waratahs playing? Well enough to go to the Chiefs in New Zealand this week and feel quietly confident.
Ewen McKenzie's fine-tuning is starting to pay dividends
Paul Cully Tumult, regardless of its nature, always creates an edge.
McMeniman's efforts will make Deans think
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Genia's return must give Lions food for thought
Paul Cully The way that Will Genia has returned after knee surgery is nothing short of remarkable.
Tight five
No.13 proves lucky for Ashley-Cooper
Paul Cully Adam Ashley-Cooper is growing each week in the No.13 jersey.
Paul Cully
Hoeft helps put scrum on a firm footing
Paul Cully Could an answer to the game's most problematic area be on the horizon?
Folau shows skills to take off on the wing
Paul Cully The Herald looks at five more Wallabies positions before the British and Irish Lions series, with three Super Rugby rounds before Robbie Deans names his first squad of 25 players.
Waratahs have skill set to stop mauling by Stormers
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Brumbies must soar to great heights at altitude
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Brumbies' northern exposure the Chiefs' concern
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Paul Cully Jake White said before the Bulls game that he had nothing to prove to the Australian Rugby Union.


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Thought you might get a kick out of reading a couple of rebuttals to the Orlando Sentinel's ranking of Georgia's football team as No. 64.
First, from Barrett Sallee of CollegeFootballNews.com:
A blog post in the Orlando Sentinel got the Georgia Bulldog fan base up in arms Tuesday –- and rightfully so.
In their College Football 2010 Countdown, the newspaper ranked the Georgia Bulldogs No. 64 … one spot behind Ole Miss and two spots behind Mississippi State. That puts them among the 25 worst BCS teams in the country.
Georgia is a bit of a mystery this season. They are breaking in a new quarterback, installing a new defensive scheme and replacing six starters on a defense that was dreadful last season. But ranking them at No. 64 is just plain ridiculous. A favorable schedule and an above average running game will get the Bulldogs into the top half of the SEC in 2010, which is a far cry from No. 64.
It's a Florida-based paper, so the rivalry between Florida and Georgia probably
Continue reading Bulldogs No. 64? 'Just plain ridiculous' ranking draws rebuttals »


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Backstreet Boys revealed some news on today's Good Morning America that's bound to change summer vacation plans for their fans. The group is adding some U.S. and Canadian dates to their ongoing "In a World Like This" world tour.
"We're coming back out on tour in the U.S. and Canada this summer," Kevin Richardson announced, with the rest of the band by his side, in a pre-recorded announcement from Norway, where they're on the road. "And guess what?" he added. "We're going to have special guest -- Avril Lavigne ," he revealed, with Brian Littrell chiming in.
Tickets for the show, including VIP packages, go on sale Friday, March 21, with the U.S. and Canadian dates kicking off May 3 in Moncton, New Brunswick. The band will make their first appearance in the U.S. on May 22 in Seattle, then head cross-country, wrapping June 22 in Jones Beach, New York.
The start gives the boys about a month to rest up after wrapping up the current European leg of their tour April 5 in Manchester, England. They're scheduled to return there in late June and early July for three more dates, after which they'll get another break before embarking on their four-day fan cruise, which begins October 24.
Avril's in the midst of her own South American tour , with the last four dates extending past the May 3 start of the BSB outing.
See dates and ticket purchase info for the U.S. and Canadian stops at BackstreetBoys.com .
Copyright 2014 ABC News Radio


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Flowers Book Plate Labels
- Add your name to all your belongings with these stylish and floral book labels.
Bees, birds and blooms adorn the four designs in this set of book plates from artist Anne Keenan Higgins. Use them to mark gardening books, seed catalogs, novels or even your Farmer's Almanac.
� 2008 Anne Keenan Higgins
- Self-adhesive labels measure 3.5" x 2.5" (3-1/2" x 2-1/2")
- Sold in sets of 32 labels (4 sheets, 8 labels per sheet)
- Personalized book plate labels are perfect for marking all your books, folders, belongings and more


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During September of last year my wife needed to convalesce after an operation so she decided to stay in Lancashire for a couple of weeks to enjoy the fresh air, scenery & peace. She found a very quiet place, unfortunately she didn't realise until she got there how remote it was. When she got to the property, which up hill... More
- Also Known As:
- Parson Lee Farm Colne, England


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Awards honor Henrico students
The Mills E. Godwin String Ensemble provided prelude music and the Highland Springs High School Choir/Ensemble provided choral music at the 45th Annual Brotherhood Sisterhood Youth Award Ceremony, held February 23 at The River Road Church, Baptist. Among the honorees were 20 Henrico County residents and students, including one recent immigrant to the United States from Myanmar (Burma).
Sponsored by the Interfaith Council of Greater Richmond, the awards annually honor students from local public, private and parochial schools who have schools who have been nominated by their school counselors, administrators and classmates for their efforts to improve human relations, enhance understanding among people of diverse backgrounds, and model empathy and caring for others.
At The Academy at Virginia Randolph, for instance, Elisabeth J. Hutson participates in the AVR Peer Mentoring Program, Jobs for America's Graduates, and Skills USA. She is known for her ability to be a team player, relate to others from diverse populations, and act as a voice of reason when conflict arises.
Justin Bartlett of Varina High School, who aspires to a career in educational leadership and administration, belongs to Key Club, Beta Club, and National Honor Society and works a part-time job at Famous Footwear. As president of the senior class and a member of the student congress, he is known for interacting well with other students and helping them to have their voices heard.
A volunteer for Angel Food Ministries, Raven Sharrieff of the Hanover Center for Trades and Technology also serves as the manager for the boys basketball and soccer teams. Her coaches say that Raven models appropriate encouragement and confidence and that the boys reflect the respect she demonstrates toward them. In addition to helping to care for a grandmother with Alzheimer's disease, she worked with a boy at summer basketball camp who has autism, helping him to build confidence and feel part of the team.
As chief reporter and lead anchor on the school news station at Hermitage Technical Center, Jordan Taylor has brought mentally, physically, and emotionally challenged children on air in the studio to have them assist with news broadcasts and to enhance their visibility in the community. He is also a teacher aide, a member of the Tech Ethics Society and Henrico County Division of Police Explorer Post #608, a mentor to physically and mentally handicapped
students, and a volunteer helper for students who are being bullied and harassed.
At The New Community School, John T. Whitty III is known for his kindness and polite ways, as well as his willingness to volunteer to help other students who need assistance or partners for projects. He is always ready to lend a hand when his peers need a big brother, friend, or classroom support person, and he knows how to intervene early in a situation and prevent confrontations.
A member of Project Diversity, a group that celebrates and showcases the diverse cultures and religions at Glen Allen High School, Soemi Nava-Ovalle is known as a calming influence during heated debates and for her ability to relate well to students from all backgrounds. After seeing some exceptional education students being bullied at school, Nava-Ovalle championed a campaign called Stand Up/Speak Out, which advocates for the rights of students with special needs.
Sarah Gaines Pearce founded the Campus Feminism Club at St. Catherine's School and is also an avid crusader for the campus Gay/Straight Alliance. With the Feminism Club, she leads a regular lunchtime conversation group, and works to bring in outside speakers, including a recent expert who spoke about the traditions of Muslim women.
Founder of the Earth Service Corps at Deep Run High School, Liesa Collins also is a youth group leader at Gayton Kirk Presbyterian Church and a youth elder for session meeting at her church. In addition to working with the Key Club, Student Congress and SODA, she volunteers at the YMCA and provides swim lessons to children of diverse backgrounds.
As junior class president at Godwin High School, Carter LaBoue was asked what the class officers' legacy should be, and responded that he wanted to be a member of the first senior class that would mentor freshmen rather than hazing him. In addition to leading the newly-created senior-freshman mentoring program, LaBoue made a point of walking around the cafeteria during the first week of school and starting up a conversation with anyone eating alone, then introducing students to each other and helping them establish connections.
Calyssa S. Baig of Highland Springs Technical Center has served in the Interact Club and as a class officer and Tech Center student ambassador. Known for her friendliness and her caring and giving spirit, she attended the Student Leadership Conference, served on the Homecoming Committee, volunteers at the food bank, and is a member of
the Technology Student Association.
At Northstar Academy, Chris McKenna has appointed himself the arbiter of birthdays. Whenever he knows of a student's birthday, he leads the cafeteria in song and celebration. A volunteer at St. Peter's Church homeless feeding program, McKenna helps welcome new and visiting students, assists middle school students who have behavior
difficulties at school, and encourages his peers to focus on their abilities rather than disabilities.
The captain of the lacrosse team at Freeman High School, Stephen Goddard is also a member of the National Honor Society and a volunteer for CARITAS. In addition to tutoring students at Maybeury Elementary School and at Freeman, he volunteers many hours coaching 10- to 12-year-olds at the Boys and Girls Club of Richmond, teaching youngsters not only how to be better athletes on the field but also how to apply lessons in off-the-field situations.
As a peer advisor and a coordinator of the MADE Mentoring program, Marshall Mayhew of St. Christopher's School shows his ninth-grade group that it is 'cool' to be open to ideas and opinions different from one's own. The faculty advisor of the peer mentoring group comments, "Reaching out to others is a natural part of who Marshall is. He selflessly and enthusiastically engages the younger guys in activities and discussions that help boost their self-confidence and self-awareness."
Jason Bass of Benedictine College Preparatory School has logged well over 100 hours of community service with organizations such as the Special Olympics, Police Athletic League, and The Salvation Army. Over the past three years, he has organized and spearheaded the Cheer for Gear campaign, which has collected more than $4,000 worth of sports equipment and athletic gear for low-income children who would otherwise be unable to participate in sports.
At J.R. Tucker High School, Valentina Vega founded and serves as president of the Latino Association for Personal Success (LAPS) club, which empowers Latino students and promotes their education. Valentina also tutors elementary through high school Arabic-speaking students in English, tutors French to other Tucker students, serves
as a bingo volunteer for senior citizens and is active in the Key Club and PTSA.
As co-chair of the student government at The Collegiate School, Jordan Lee is known as a skillful consensus-builder and unifier who excels at conflict resolution and works to include many voices while striving to represent them fairly and equally. He is also a member of the Mosaic Diversity Club, and serves as an ambassador and guest speaker at the Collegiate Emerging Leaders International Conference, welcoming and hosting students from 12 schools around the world.
Ellie Iverson of The Steward School is a member of the Stewardship Club and volunteers at the Skills Development Center, Patrick Henry's Promise and Northstar Academy.
"Ellie," said her nominators, "is the ideal role model for others on how to be an inclusive, caring friend to all. She encourages others to be giving and she herself has a low tolerance of self-centeredness."
When Jennifer Titus of Hermitage High School was offered a study hall due to a scheduling conflict, she refused it -- despite a rigorous course of studies and activites such as captaining the cheerleading squad and volunteering for Triangle II Community Service -- and asked to tutor exceptional students instead. "What separates Jennifer from
other students," said her nominator, "is her ability to see the person and not the disability. . . When the students see her in the classroom, they are very eager to work with her on various lessons or tasks."
After only three years in this country, Samuel Uk Ceu Lian of Henrico High School has become an inspiration to all the students in his ESL class. Active in the school's Spirit Club, he has become an interpreter for the Chin Community, a youth leader in his church, a varsity soccer player and a member of the robotics team. His peers know -- despite his struggles to learn not only content but also the language used both in and out of the classroom -- that he can be
counted on to try and defuse any situation and handle classroom disturbances with tact.
A student at Highland Springs High School, Andrew L. Compton uses his musical talents to brighten the lives of visitors to the homeless shelter at which he volunteers, as well as to lead youth worship at his church. He has traveled to Atlanta, Philadelphia and East Asia on mission trips, volunteers at the LAMB's Basket food bank, is president of the National Honor Society and Spanish Honor Society, and is known among nursing home patients and students alike for his compassionate listening ear.
"Perhaps Andrew's most impressive quality," wrote a nominator, "is the humility that he displays in all things, knowing that he has much more to learn in his life, that he is not a perfect individual, and that every moment is a learning opportunity for the future."
Lions Club donates backpacks to elementary school
The Richmond West Breakfast Lions Club (based in western Henrico) recently donated 59 backpacks to the Westover Hills Elementary School on Jahnke Road.
Above, club members display some of the backpacks prior to their distribution. > Read more.
Glen Allen student to perform at Carnegie Hall
Thanks to a first-place win in The American Protege International Vocal Competition 2014, Glen Allen High School student Matija Tomas will travel to New York City to perform at Carnegie Hall in December.
At the first-place winners recital in Weill Hall, Matija will perform Giacomo Puccini's opera aria, "Chi il bel sogna di doretta." She will perform with other vocalists from around the world and have the opportunity to win other awards and scholarships.
Locally, Thomas has performed with Richmond's renowned Glorious Christmas Nights, Christian Youth Theatre, and WEAG's Urban Gospel Youth Choir. > Read more.
Gayton Baptist Church dedicates new outreach center
The John Rolfe YMCA and Gayton Baptist Church have partnered in an effort to bring greater health and wellness opportunities to the community.
Through this partnership, the John Rolfe Y will run Youth Winter Sports programs, including basketball and indoor soccer, in Gayton's newly renovated $5.5 million outreach center that features a new gymnasium, youth and teen space, social space with café, meeting space and full service commercial kitchen. > Read more.
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Restaurant watch
Find out how your favorite dining establishments fared during their most recent inspections by the Virginia Department of Health. > Read more.
CAT Theatre announces cast of Sherlock Holmes play
CAT Theatre's 51st season will open with Sherlock Holmes: The Final Adventure, which will run from Oct. 24-Nov. 8. Adapted by Steven Dietz, it is based on the original 1899 play by William Gillette and Sir Arthur Conan Doyle and was the winner of the 2007 Edgar Award for Best Mystery Play.
The plot follows what seems to be the end of the career of the world's greatest detective as he is confronted with a case far too tempting to ignore. When the King of Bohemia faces blackmail by famed opera singer Irene Adler, Holmes and his faithful companion, Dr. Watson, find themselves falling into the trap of evil genius Professor Moriarty. As Holmes says, "The game is afoot Watson, and it is a dangerous one!" > Read more.
Extras sought for AMC's 'TURN'
Paid extras are being sought to appear in the AMC television series TURN: Washington's Spies, which will begin filming its second season in the Richmond area at the end of September and continue through February.
No experience is required, but producers say that extras must have flexible availability, reliable transportation and a positive attitude.
Arvold Casting is holding an open call on Sunday, Sept. 21 and is seeking men, women and children who are Caucasian, African American and Native American, with thin to average builds and who can realistically portray people living in Revolutionary War times. Long hair is a plus but not a must. > Read more.
Moving on up
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From Proteopedia
|3c2i, resolution 2.50Å ()
|Non-Standard Residues:
|MECP2 (Homo sapiens)
|FirstGlance, OCA, RCSB, PDBsum
|save as pdb, mmCIF, xml
The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF
MeCP2 is an essential transcriptional repressor that mediates gene silencing through binding to methylated DNA. Binding specificity has been thought to depend on hydrophobic interactions between cytosine methyl groups and a hydrophobic patch within the methyl-CpG-binding domain (MBD). X-ray analysis of a methylated DNA-MBD cocrystal reveals, however, that the methyl groups make contact with a predominantly hydrophilic surface that includes tightly bound water molecules. This suggests that MeCP2 recognizes hydration of the major groove of methylated DNA rather than cytosine methylation per se. The MeCP2-DNA complex also identifies a unique structural role for T158, the residue most commonly mutated in Rett syndrome.
MeCP2 binding to DNA depends upon hydration at methyl-CpG., Ho KL, McNae IW, Schmiedeberg L, Klose RJ, Bird AP, Walkinshaw MD, Mol Cell. 2008 Feb 29;29(4):525-31. PMID:18313390
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
[MECP2_HUMAN] Defects in MECP2 may be a cause of Angelman syndrome (AS) [MIM:105830]; also known as happy puppet syndrome. AS is a neurodevelopmental disorder characterized by severe mental retardation, absent speech, ataxia, sociable affect and dysmorphic facial features. AS and Rett syndrome have overlapping clinical features.[1][2] Defects in MECP2 are the cause of mental retardation syndromic X-linked type 13 (MRXS13) [MIM:300055]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRXS13 patients manifest mental retardation associated with other variable features such as spasticity, episodes of manic depressive psychosis, increased tone and macroorchidism.[3][4][5][6][7][8][9][10][11] Defects in MECP2 are the cause of Rett syndrome (RTT) [MIM:312750]. RTT is an X-linked dominant disease, it is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood.[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] Defects in MECP2 may be the cause of susceptibility autism X-linked type 3 (AUTSX3) [MIM:300496]. AUTSX3 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.[34] Defects in MECP2 are the cause of encephalopathy neonatal severe due to MECP2 mutations (ENS-MECP2) [MIM:300673]. Note=The MECP2 gene is mutated in Rett syndrome, a severe neurodevelopmental disorder that almost always occurs in females. Although it was first thought that MECP2 mutations causing Rett syndrome were lethal in males, later reports identified a severe neonatal encephalopathy in surviving male sibs of patients with Rett syndrome. Additional reports have confirmed a severe phenotype in males with Rett syndrome-associated MECP2 mutations.[35] Defects in MECP2 are the cause of mental retardation syndromic X-linked Lubs type (MRXSL) [MIM:300260]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRXSL patients manifest mental retardation associated with variable features. They include swallowing dysfunction and gastroesophageal reflux with secondary recurrent respiratory infections, hypotonia, mild myopathy and characteristic facies such as downslanting palpebral fissures, hypertelorism and a short nose with a low nasal bridge. Note=Increased dosage of MECP2 due to gene duplication appears to be responsible for the mental retardation phenotype.
[MECP2_HUMAN] Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.
About this Structure
3c2i is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
- Ho KL, McNae IW, Schmiedeberg L, Klose RJ, Bird AP, Walkinshaw MD. MeCP2 binding to DNA depends upon hydration at methyl-CpG. Mol Cell. 2008 Feb 29;29(4):525-31. PMID:18313390 doi:10.1016/j.molcel.2007.12.028
- ↑ Inui K, Akagi M, Ono J, Tsukamoto H, Shimono K, Mano T, Imai K, Yamada M, Muramatsu T, Sakai N, Okada S. Mutational analysis of MECP2 in Japanese patients with atypical Rett syndrome. Brain Dev. 2001 Jul;23(4):212-5. PMID:11376998
- ↑ Watson P, Black G, Ramsden S, Barrow M, Super M, Kerr B, Clayton-Smith J. Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein. J Med Genet. 2001 Apr;38(4):224-8. PMID:11283202
- ↑ Meloni I, Bruttini M, Longo I, Mari F, Rizzolio F, D'Adamo P, Denvriendt K, Fryns JP, Toniolo D, Renieri A. A mutation in the rett syndrome gene, MECP2, causes X-linked mental retardation and progressive spasticity in males. Am J Hum Genet. 2000 Oct;67(4):982-5. Epub 2000 Sep 12. PMID:10986043 doi:10.1086/303078
- ↑ Orrico A, Lam C, Galli L, Dotti MT, Hayek G, Tong SF, Poon PM, Zappella M, Federico A, Sorrentino V. MECP2 mutation in male patients with non-specific X-linked mental retardation. FEBS Lett. 2000 Sep 22;481(3):285-8. PMID:11007980
- ↑ Couvert P, Bienvenu T, Aquaviva C, Poirier K, Moraine C, Gendrot C, Verloes A, Andres C, Le Fevre AC, Souville I, Steffann J, des Portes V, Ropers HH, Yntema HG, Fryns JP, Briault S, Chelly J, Cherif B. MECP2 is highly mutated in X-linked mental retardation. Hum Mol Genet. 2001 Apr 15;10(9):941-6. PMID:11309367
- ↑ Klauck SM, Lindsay S, Beyer KS, Splitt M, Burn J, Poustka A. A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome. Am J Hum Genet. 2002 Apr;70(4):1034-7. Epub 2002 Feb 15. PMID:11885030 doi:10.1086/339553
- ↑ Winnepenninckx B, Errijgers V, Hayez-Delatte F, Reyniers E, Frank Kooy R. Identification of a family with nonspecific mental retardation (MRX79) with the A140V mutation in the MECP2 gene: is there a need for routine screening? Hum Mutat. 2002 Oct;20(4):249-52. PMID:12325019 doi:10.1002/humu.10130
- ↑ Laccone F, Zoll B, Huppke P, Hanefeld F, Pepinski W, Trappe R. MECP2 gene nucleotide changes and their pathogenicity in males: proceed with caution. J Med Genet. 2002 Aug;39(8):586-8. PMID:12161600
- ↑ Dotti MT, Orrico A, De Stefano N, Battisti C, Sicurelli F, Severi S, Lam CW, Galli L, Sorrentino V, Federico A. A Rett syndrome MECP2 mutation that causes mental retardation in men. Neurology. 2002 Jan 22;58(2):226-30. PMID:11805248
- ↑ Moog U, Smeets EE, van Roozendaal KE, Schoenmakers S, Herbergs J, Schoonbrood-Lenssen AM, Schrander-Stumpel CT. Neurodevelopmental disorders in males related to the gene causing Rett syndrome in females (MECP2). Eur J Paediatr Neurol. 2003;7(1):5-12. PMID:12615169
- ↑ Ventura P, Galluzzi R, Bacca SM, Giorda R, Massagli A. A novel familial MECP2 mutation in a young boy: clinical and molecular findings. Neurology. 2006 Sep 12;67(5):867-8. PMID:16966553 doi:10.1212/01.wnl.0000233990.87889.15
- ↑ Inui K, Akagi M, Ono J, Tsukamoto H, Shimono K, Mano T, Imai K, Yamada M, Muramatsu T, Sakai N, Okada S. Mutational analysis of MECP2 in Japanese patients with atypical Rett syndrome. Brain Dev. 2001 Jul;23(4):212-5. PMID:11376998
- ↑ Watson P, Black G, Ramsden S, Barrow M, Super M, Kerr B, Clayton-Smith J. Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein. J Med Genet. 2001 Apr;38(4):224-8. PMID:11283202
- ↑ Laccone F, Zoll B, Huppke P, Hanefeld F, Pepinski W, Trappe R. MECP2 gene nucleotide changes and their pathogenicity in males: proceed with caution. J Med Genet. 2002 Aug;39(8):586-8. PMID:12161600
- ↑ Mnatzakanian GN, Lohi H, Munteanu I, Alfred SE, Yamada T, MacLeod PJ, Jones JR, Scherer SW, Schanen NC, Friez MJ, Vincent JB, Minassian BA. A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome. Nat Genet. 2004 Apr;36(4):339-41. Epub 2004 Mar 21. PMID:15034579 doi:10.1038/ng1327
- ↑ Wan M, Lee SS, Zhang X, Houwink-Manville I, Song HR, Amir RE, Budden S, Naidu S, Pereira JL, Lo IF, Zoghbi HY, Schanen NC, Francke U. Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots. Am J Hum Genet. 1999 Dec;65(6):1520-9. PMID:10577905 doi:10.1086/302690
- ↑ Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet. 1999 Oct;23(2):185-8. PMID:10508514 doi:10.1038/13810
- ↑ Buyse IM, Fang P, Hoon KT, Amir RE, Zoghbi HY, Roa BB. Diagnostic testing for Rett syndrome by DHPLC and direct sequencing analysis of the MECP2 gene: identification of several novel mutations and polymorphisms. Am J Hum Genet. 2000 Dec;67(6):1428-36. Epub 2000 Oct 30. PMID:11055898 doi:10.1086/316913
- ↑ Cheadle JP, Gill H, Fleming N, Maynard J, Kerr A, Leonard H, Krawczak M, Cooper DN, Lynch S, Thomas N, Hughes H, Hulten M, Ravine D, Sampson JR, Clarke A. Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location. Hum Mol Genet. 2000 Apr 12;9(7):1119-29. PMID:10767337
- ↑ Bienvenu T, Carrie A, de Roux N, Vinet MC, Jonveaux P, Couvert P, Villard L, Arzimanoglou A, Beldjord C, Fontes M, Tardieu M, Chelly J. MECP2 mutations account for most cases of typical forms of Rett syndrome. Hum Mol Genet. 2000 May 22;9(9):1377-84. PMID:10814719
- ↑ Amano K, Nomura Y, Segawa M, Yamakawa K. Mutational analysis of the MECP2 gene in Japanese patients with Rett syndrome. J Hum Genet. 2000;45(4):231-6. PMID:10944854 doi:10.1007/s100380070032
- ↑ Xiang F, Buervenich S, Nicolao P, Bailey ME, Zhang Z, Anvret M. Mutation screening in Rett syndrome patients. J Med Genet. 2000 Apr;37(4):250-5. PMID:10745042
- ↑ Obata K, Matsuishi T, Yamashita Y, Fukuda T, Kuwajima K, Horiuchi I, Nagamitsu S, Iwanaga R, Kimura A, Omori I, Endo S, Mori K, Kondo I. Mutation analysis of the methyl-CpG binding protein 2 gene (MECP2) in patients with Rett syndrome. J Med Genet. 2000 Aug;37(8):608-10. PMID:10991688
- ↑ Hampson K, Woods CG, Latif F, Webb T. Mutations in the MECP2 gene in a cohort of girls with Rett syndrome. J Med Genet. 2000 Aug;37(8):610-2. PMID:10991689
- ↑ Armstrong J, Pineda M, Aibar E, Gean E, Monros E. Classic Rett syndrome in a boy as a result of somatic mosaicism for a MECP2 mutation. Ann Neurol. 2001 Nov;50(5):692. PMID:11706982
- ↑ Giunti L, Pelagatti S, Lazzerini V, Guarducci S, Lapi E, Coviello S, Cecconi A, Ombroni L, Andreucci E, Sani I, Brusaferri A, Lasagni A, Ricotti G, Giometto B, Nicolao P, Gasparini P, Granatiero M, Uzielli ML. Spectrum and distribution of MECP2 mutations in 64 Italian Rett syndrome girls: tentative genotype/phenotype correlation. Brain Dev. 2001 Dec;23 Suppl 1:S242-5. PMID:11738883
- ↑ Laccone F, Huppke P, Hanefeld F, Meins M. Mutation spectrum in patients with Rett syndrome in the German population: Evidence of hot spot regions. Hum Mutat. 2001 Mar;17(3):183-90. PMID:11241840 doi:10.1002/humu.3
- ↑ Vacca M, Filippini F, Budillon A, Rossi V, Mercadante G, Manzati E, Gualandi F, Bigoni S, Trabanelli C, Pini G, Calzolari E, Ferlini A, Meloni I, Hayek G, Zappella M, Renieri A, D'Urso M, D'Esposito M, MacDonald F, Kerr A, Dhanjal S, Hulten M. Mutation analysis of the MECP2 gene in British and Italian Rett syndrome females. J Mol Med (Berl). 2001;78(11):648-55. PMID:11269512
- ↑ Hoffbuhr K, Devaney JM, LaFleur B, Sirianni N, Scacheri C, Giron J, Schuette J, Innis J, Marino M, Philippart M, Narayanan V, Umansky R, Kronn D, Hoffman EP, Naidu S. MeCP2 mutations in children with and without the phenotype of Rett syndrome. Neurology. 2001 Jun 12;56(11):1486-95. PMID:11402105
- ↑ Conforti FL, Mazzei R, Magariello A, Patitucci A, Gabriele AL, Muglia M, Quattrone A, Fiumara A, Barone R, Pavone L, Nistico R, Mangone L. Mutation analysis of the MECP2 gene in patients with Rett syndrome. Am J Med Genet A. 2003 Mar 1;117A(2):184-7. PMID:12567420 doi:10.1002/ajmg.a.10898
- ↑ Hammer S, Dorrani N, Hartiala J, Stein S, Schanen NC. Rett syndrome in a 47,XXX patient with a de novo MECP2 mutation. Am J Med Genet A. 2003 Oct 15;122A(3):223-6. PMID:12966522 doi:http://dx.doi.org/10.1002/ajmg.a.20320
- ↑ Smeets E, Schollen E, Moog U, Matthijs G, Herbergs J, Smeets H, Curfs L, Schrander-Stumpel C, Fryns JP. Rett syndrome in adolescent and adult females: clinical and molecular genetic findings. Am J Med Genet A. 2003 Oct 15;122A(3):227-33. PMID:12966523 doi:http://dx.doi.org/10.1002/ajmg.a.20321
- ↑ Schanen C, Houwink EJ, Dorrani N, Lane J, Everett R, Feng A, Cantor RM, Percy A. Phenotypic manifestations of MECP2 mutations in classical and atypical Rett syndrome. Am J Med Genet A. 2004 Apr 15;126A(2):129-40. PMID:15057977 doi:10.1002/ajmg.a.20571
- ↑ Carney RM, Wolpert CM, Ravan SA, Shahbazian M, Ashley-Koch A, Cuccaro ML, Vance JM, Pericak-Vance MA. Identification of MeCP2 mutations in a series of females with autistic disorder. Pediatr Neurol. 2003 Mar;28(3):205-11. PMID:12770674
- ↑ Imessaoudene B, Bonnefont JP, Royer G, Cormier-Daire V, Lyonnet S, Lyon G, Munnich A, Amiel J. MECP2 mutation in non-fatal, non-progressive encephalopathy in a male. J Med Genet. 2001 Mar;38(3):171-4. PMID:11238684


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With my heart in my mouth, I'm coming clean on my blog today. I don't know why it's taken this long. Perhaps it's that creative perfection gene that runs so strongly through my veins. It's not good enough, it needs more spit-and-polish, what if they reject me….
For those of you who don't follow me on Twitter or Facebook and just rely on blog posts to keep updated with my latest, about a week ago I put the first 14 chapters of my book – Into The Bliss: Having & Holding Ellanor – up online for public reading.
If you would like to get a feel for the book and what I've been banging on about for the past five years (and thank you for staying and listening if you've been with me on the journey for any of that time!), you are welcome to read it. A comment or some sort of feedback would be lovely (many of you creative/writerly types would understand the way that makes a heart sing), but it's not necessary. The gift is in being able to share it with you and I give it out in good faith that it will reach the eyes and touch the hearts of those of you needing to find something in it.
I wrote it not for me. Not to settle scores. Not to rewrite history or state facts or lay claim to grief. I wrote it for everything. Everyone. The All of this thing called life, and the intangible but undeniable realm that lies beyond life – in both directions.
Actually, that's not entirely true. It pretty much wrote itself. The working title of this book, in the beginning, was a joke between myself and Steve. We actually called it "This Thing Writes Itself." I was floored at the way it came together. I was humbled into something akin to stage fright at the story I could see. The realisations that came to me as I would quickly fumble for the light switch and write thoughts down on paper in the middle of the night. Sometimes, I would have entire chapters hanging in my head like heavy water balloons. I would get up, freezing cold in the dead of winter, wrap myself in something warm, pray that the LGBB wouldn't get up too early (she was seven months old when I began this) and burst them onto my Word document. Woken by her. Ellanor. I would come out of sleep with her urging me out into the still, silent house so that I could capture the magic. Occasionally, I'd try and do it without waking too much – I would type with my hands flying across the keyboard, eyes closed, still half asleep, drearily hit the 'Save' command and drop back into bed with barely half an hour before the LGBB was likely to wake.
I came to discover that my best and most creative, uninterrupted time was between 2am and about 6 in the morning just as the dawn crept in. Poetic, wouldn't you say?
I wrote myself out of the dark both literally and …. literaril..y…. during the course of writing this book.
But despite this, I maintain, I didn't write it for me. It was merely a wonderful bonus, to be able to explore the depths of this far-reaching thing called Life. See what you think. Don't be afraid! It's not as indulgently doomy and gloomy a pity-party as one might expect. In fact, rather the opposite. Well… so I'm told (it's hard to be objective about such things as the author).
I have a couple of public massive thank you's to offer, at this point, because I'm so grateful for what I have received — from Shae (from Free Range In Suburbia) who shares top billing in my blogging circle for being one of only two people so far who has read the entire book; the generous and highly gifted author in his own right, Steve (from Bloggertropolis) is the other who made it to the last page; Toushka Lee (from Toushkalee.com) who I've also entrusted the whole book to (thank you, T!); Suz (who writes at Autism Our Words); Anna (as in, Anna Spargo-ryan… she writes proper like, for a living… I am not worthy) who is sticking with it and meandering somewhere in the latter chapters and possibly regretting putting her hand up and admitting she liked the memoir genre; Naomi (who can be found Under The Yardarm), my dear friend Allie from my first foray into online forums eight years ago (who blogs In A Beautiful Pea Green Boat) and also a number of other generous friends from my Facebook world who don't have blogs but who have been stalwart readers, supporters and cheerleaders during this long process. They've read varying versions as the book has been drafted, redrafted, heavily edited, cut and spliced since 2007. Some of them would possibly hardly recognise the story if they read it now.
What do you think? Will you read it? Have you read it? If you give the chapters on Authonomy.com a go and feel it worthy, please help me spread the word. My aim is to get an agent for this. I'm working on it. I'm told time and again that it's a book that "needs to be published". However, "needs" and "will" remain two vastly different realities.
It's like winning the lottery, I know….


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Alfred "Frano" Francis on Jamaica
Alfred "Frano" Francis, executive member of the Jamaican Athletics Association, talks about the fine ingredients that make Jamaican athletes stand out from the pack.
Performance-enhancing products for those who thrive on the homestretch and live off endorphins.
PUMA is on a sustainability journey to improve our business and the lives of generations to come.


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Keep your head warm and cozy while showing your support in a big way with this Oakland Raiders New Era Woven Biggie Knit Hat. This super cool knit hat features a large woven Raiders shield logo on the crown and a smaller logo embroidered on the cuff, and a team-colored pom on top gives this hat an extra touch of Raider pride that won't go unnoticed. 100% AcrylicOur apologies, due to Mexico's trading policies this item cannot be shipped to Mexico.


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The 'Radiance' range from Royal Doulton features a multi faceted cut and a 24% lead crystal design that gives it a glamorous sparkle, reflecting the light for an eye catching look. This set of three mini photo frames includes a faceted sphere, a square and a hexagon design, great for displaying your favourite pictures in style.
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liraglutide, Victoza
Pharmacy Author:
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Jay W. Marks, MD
Jay W. Marks, MD
Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
GENERIC NAME: liraglutide
BRAND NAME: Victoza
DRUG CLASS AND MECHANISM: Liraglutide is an injectable drug that reduces the level of sugar (glucose) in the blood. It is used for treating type 2 diabetes and is similar to exenatide (Byetta). Liraglutide belongs in a class of drugs called incretin mimetics because these drugs mimic the effects of incretins. Incretins, such as human-glucagon-like peptide-1 (GLP-1), are hormones that are produced and released into the blood by the intestine in response to food. GLP-1 increases the secretion of insulin from the pancreas, slows absorption of glucose from the gut, and reduces the action of glucagon. (Glucagon is a hormone that increases glucose production by the liver.) All three of these actions reduce levels of glucose in the blood. In addition, GLP-1 reduces appetite. Liraglutide is a synthetic (man-made) hormone that resembles and acts like GLP-1. In studies, liraglutide treated patients achieved lower blood glucose levels and experienced weight loss. Liraglutide was approved by the FDA in January 2010.
PRESCRIPTION: Yes.
GENERIC AVAILABLE: No.
PREPARATIONS: Multiple dose pre-filled pen: 18 mg in 3 ml (6 mg/ml)
STORAGE: Liraglutide should be refrigerated between 2-8 C (36-46 F) prior to first use. After the first use it can be stored at room temperature 15-30 C (59-86 F) or refrigerated at 2-8 C (36-46 F).
PRESCRIBED FOR: Liraglutide is used with diet and exercise to improve control of blood sugar in adults with type 2 diabetes mellitus. Liraglutide should not be used for treating diabetic ketoacidosis or type 1 diabetes and should not be used as the first agent for treating diabetes after failure of diet and exercise.
DOSING: Liraglutide is injected under the skin of the abdomen, thigh, or upper arm. Each pre-fiilled pen can deliver 0.6, 1.2, and 1.8 mg doses. The initial dose is 0.6 mg daily for one week. The initial dose helps the body to build a tolerance to stomach related side effects. It is not effective for controlling blood glucose. After one week the dose is increased to 1.2 mg daily. The maximum dose is 1.8 mg daily.
DRUG INTERACTIONS: Liraglutide slows down transit of food and drugs through the intestine and, therefore, may reduce the absorption of drugs that are taken orally. Although liraglutide did not significantly affect the absorption of oral dugs tested in studies, it is still prudent to separate administration of liraglutide and oral medications. Combining liraglutide with insulin or drugs that stimulate release of insulin (for example, glyburide [Micronase, Diabeta, Glynase, Prestab]) may increase the occurrence of low blood sugar (hypoglycemia). The dose of insulin or the insulin release stimulating drug should be reduced.
PREGNANCY: There are no adequate studies of liraglutide in pregnant women. Most experts agree that insulin is the drug of choice in pregnant women with diabetes.
NURSING MOTHERS: There are no adequate studies of liraglutide in nursing mothers, and it is not known whether liraglutide is excreted in human breast milk.
SIDE EFFECTS: The most common side effects of liraglutide are nausea, vomiting, diarrhea, constipation, upper respiratory tract infection, and headache. Patients also may experience flu like symptoms, dizziness, sinusitis, back pain, and reactions at the injection site.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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UMC is a customer-driven company always willing to explore new technologies and be asked "what if". As you will see, UMC has up to date and well maintained manufacturing equipment, but it is our people that make us more than just another Printed Circuit Board manufacturer.
Throughout our website, we hope to share our capabilities, facilities, and hopefully our enthusiasm to help you make informed decisions regarding your PCB requirements. Once again, welcome and please don't hesitate to contact us for further information.
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Start learning with our library of video tutorials taught by experts. Get started
An insider's look into the process of building interactive web applications using Silverlight.
"I have yet to find a course that I didn't find useful, well organized, and informative. And it's always at my fingertips." —Leslie M.
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FRANKFORT, Ky. (AP) -- Kentucky poet laureate Frank X Walker is among the nominees for the 45th annual NAACP Image Awards.
Walker is nominated in the category of Outstanding Literary Work - Poetry for his latest book, "Turn Me Loose: The Unghosting of Medgar Evers."
The NAACP Image Awards highlight achievements in art, entertainment, politics and culture. The nominees and winners of the awards are selected by a group of NAACP members.
Walker says he was excited to find out about the nomination.
Walker is an associate professor of English at the University of Kentucky.
The NAACP Image Awards will be announced Feb. 21 for non-televised categorie


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JACK'S 9TH SHOW: Complete Details | Set Times | Photos
Taxi Dave's Black and Yellow Cab Will Thrill You In Sacramento [VIDEO]
Hey Lazy McRideless. Listen up! If you're ever in Sacramento (or Sacktown to some) be sure to dial 916-862-0445 and have Taxi Dave pick ya up! After all, he's the hippest cabbie this side of […]