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Boehringer Ingelheim
Media & PR
Julia Meyer-Kleinmann
Binger Strasse 173
55216 Ingelheim am Rhein
Data from pre-specified interim analysis of Phase IIb SOUND-C21 trial with Boehringer Ingelheim's two investigational HCV direct-acting antivirals presented at AASLD
For media outside of the U.S.A. only
San Francisco, USA and Ingelheim, Germany [7 November 2011] – Boehringer Ingelheim today announced results from a pre-specified interim analysis of a Phase IIb study, named SOUND-C2. These data showed the combination of two oral direct acting anti hepatitis C virus (HCV) compounds (the protease inhibitor BI 201335 and the polymerase inhibitor BI 207127, with and without ribavirin (RBV), was successful in providing virological response rates at week 12 in treatment-naïve patients infected with the most difficult to treat genotype-1 (GT1) HCV.1 The shortest treatment duration tested in the study (16 weeks) achieved SVR12 in 59% of patients. None of the five study arms included treatment with interferon.1,2 These data were presented today at the American Association for the Study of Liver Diseases (AASLD) 2011 Liver Meeting in San Francisco, USA.1
"Results from the interim analysis of SOUND-C2 look promising," said Stefan Zeuzem, M.D., Chief of the Department of Medicine and Professor of Medicine at the Johann Wolfgang Goethe University Hospital in Frankfurt, Germany and lead investigator of the study. "They highlight the potential of BI 201335 plus BI 207127 to lessen the burden of existing treatments for a large portion of patients by offering a potential treatment option without the inclusion of interferon."
The use of interferon in HCV treatment is challenging for a number of patients due to suboptimal response rates, contraindications or severe side effects and treatment durations.3
"We very much look forward to the final results from the SOUND-C2 study. The development of an oral interferon-free direct-acting antiviral regimen underlines Boehringer Ingelheim's goal of eliminating interferon from HCV treatment and a commitment to deliver innovative novel treatments in virology," said Professor Klaus Dugi, Corporate Senior Vice President Medicine at Boehringer Ingelheim. "At AASLD we will also present further data from anti-HCV portfolio that demonstrates our dedication to meet the real-world challenges of HCV patients globally,1,4–7 including patient populations with traditionally difficult to treat virus types." 8–10
All five treatment arms of the interferon-free oral combination therapy of BI 201335/BI 207127/RBV showed high virologic response rates through week 12, defined by measuring the level of HCV RNA in patient blood:
The safety and tolerability profile was comparable to other direct acting antiviral regimens.
Other BI data being presented at the meeting include:
Results of this open-label, randomised, Phase IIb study were presented as a late breaking poster titled, "Virologic response to an interferon-free regimen of BI201335 and BI207127, with and without ribavirin, in treatment-naive patients with chronic genotype-1 HCV infection: Week 12 interim results of the SOUND-C2 study," by Professor Stefan Zeuzem. In the study, 362 treatment-naïve GT1 HCV patients were randomised into five interferon-free treatment groups, each with 120mg BI 201335 once daily but with different dosing of BI 207127 and treatment durations as follows:
About Hepatitis C Virus (HCV)
HCV is an infectious disease of the liver and is a leading cause of chronic liver disease and liver transplant. The number of individuals chronically infected with HCV globally has been estimated at 175 million, with 3–4 million new infections occurring each year. Only about 20–45% of patients clear the virus in the acute phase. Of the remaining chronically infected patients, 20% will develop cirrhosis within a mean of 20 years. The mortality rate after cirrhosis has developed is 2-5% per year. End-stage liver disease due to HCV infection currently represents the major cause for liver transplantation in the Western world.
About Boehringer Ingelheim in Virology
Boehringer Ingelheim has more than 7,500 scientists working in cross disciplinary teams within our global R&D network in six large therapeutic areas, including virology. In addition to its ongoing research program for HCV, Boehringer Ingelheim has a longstanding history in virology drug development, including compounds for the treatment of HIV (VIRAMUNE® (nevirapine) tablets/oral suspension, the first approved HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) and Aptivus®, an HIV protease inhibitor). The company has a well established research centre in Laval, Canada, dedicated to virology research since the early 1990's, and is committed to developing new therapies for virological diseases with a high unmet medical need.
Boehringer Ingelheim in Hepatitis C Virus (HCV)
Boehringer Ingelheim has a dedicated HCV treatment development programme, called HCVersoTM, which at its core, aims to reverse the existing HCV paradigm. The ultimate aim of this programme is to deliver improved HCV treatment outcomes for patients whilst breaking down the barriers of current treatment regimens.
BI 201335 is an investigational oral HCV NS3/4A protease inhibitor, discovered from Boehringer Ingelheim's own research and development, which has completed clinical trials through Phase IIb (SILEN-C studies). This Phase II programme supports the investigation of BI 201335 in Phase III trials currently ongoing. Boehringer Ingelheim is also developing BI 207127, an NS5B RNA-dependent polymerase inhibitor that has completed Phase I clinical trials. Phase II trials evaluating BI 207127 with BI 201335 in interferon-sparing regimens, both with and without ribavirin, are currently underway.
Boehringer Ingelheim
The Boehringer Ingelheim group is one of the world's 20 leading pharmaceutical companies. Headquartered in Ingelheim, Germany, it operates globally with 145 affiliates and more than 42,000 employees. Since it was founded in 1885, the family-owned company has been committed to researching, developing, manufacturing and marketing novel products of high therapeutic value for human and veterinary medicine.
As a central element of its culture, Boehringer Ingelheim pledges to act socially responsible. Involvement in social projects, caring for employees and their families, and providing equal opportunities for all employees form the foundation of the global operations. Mutual cooperation and respect, as well as environmental protection and sustainability are intrinsic factors in all of Boehringer Ingelheim's endeavors.
In 2010, Boehringer Ingelheim posted net sales of about 12.6 billion euro while spending almost 24% of net sales in its largest business segment Prescription Medicines on research and development.
SVR = sustained viral response, referred to as HCV cure. SVR12 = sustained viral response at week 12 after treatment is completed. RVR = Rapid virologic response, undetectable viral RNA at week 4 of treatment (indicator of how patient will respond). eRVR = extended rapid virologic response, undetectable viral RNA enduring through week 12 of treatment.
1. Zeuzem, Stefan, et al. Virologic response to an interferon-free regimen of BI201335 and BI207127, with and without ribavirin, in treatment-naive patients with chronic genotype-1 HCV infection: Week 12 interim results of the SOUND-C2 study.
2. Mensa, Federico J. BI 207127 – BI 201335 (O2) program Overview; IFN-sparing oral regimen. Barcelona, May 19, 2011.
3. http://www.thebody.com/content/art12308.html (last accessed 4th March 2011)
4. Dieterich, Douglas et al. SILEN-C3: Treatment for 12 or 24 weeks with BI201335 combined with peginterferon alfa-2a and ribavirin (P/R) in treatment-naïve patients with chronic genotype-1 HCV infection.
5. Kukolj, G. et al. Characterization of HCV NS3 variants that emerged during virologic breakthrough and relapse from BI 201335 phase 2 SILEN-C1 study.
6. Sulkowski, Mark et al. Treatment with the 2nd generation HCV protease inhibitor BI201335 results in high and consistent SVR rates – results from SILEN-C1 in treatment-naïve patients across different baseline factors.
7. Zeuzem, Stefan et al. High sustained virologic response following interferon-free treatment of chronic HCV GT1 infection for 4 weeks with HCV protease inhibitor BI201335, polymerase inhibitor BI207127 and ribavirin, followed by BI201335 and PegIFN/ribavirin –the SOUND-C1 study.
8. Soriano, Vicent et al. Directly acting antivirals against hepatitis C virus. Journal of Antimicrobial Chemotherapy. 2011; 66: 1673-1686.
9. Ghany, Marc et al. An Update on Treatment of Genotype 1 Chronic Hepatitis C Virus Infection: 2011 Practice Guidelines by the American Association for the Study of Liver Diseases. Hepatology, August 2011.
10. National Institutes of Health Consensus Development Program: Management of Hepatitis C, 2002. http://consensus.nih.gov/2002/2002Hepatitisc2002116html.htm.

subset: commoncrawl


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UPDATE , 5:29 p.m.
U.S. district court judge Susan Richard Nelson said she'll need a couple of weeks to determine if the NFL owners illegally locked out the players, according to several media reports.
Here's the Associated Press story. Click Here!
She urged the players and the league to take part in mediated talks.
Nelson was not expected to decide the case today. Her decision will likely be appealed and that could further stall the proceedings. Also, it must be determine if she has jurisdiction over the case or if it belongs in front of the National Labor Relations Board.
After hours of testimony, Nelson noted that she would take the case under advisement and make a decision "in a couple of weeks."
Ralph Cindrich, a former player, longtime agent and attorney, basically told everyone on twitter.com to calm down.
He tweeted, "Get real & bank on it: There will be a football season that will be fully played. Lots of hype, folks. It's part of business w the #NFL."
Continue reading NFL LOCKOUT: Judge to decide in two weeks »


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Winter has struck with a vengeance the last few weeks and so have the swells we've been getting. I hope everyone's been getting their fix and soaking it all up. Excuse our lack of updates lately but our regular IT Dude, Liam has escaped the cold and is sampling the warm waters of Mexico. From all reports hes been scoring too!
We've had plenty of new stuff hit the store in the last few weeks, JS has just unveiled his new 'PRODIGY' model. They arrived yesterday and look and feel great. The 'PRODIGY' is great for guys who love the volume of the 'Kingpin' and 'Blakbox' models but want something that will allow them to surf better waves. Features a pulled in round tail for tight turns in the pocket, a lower rail which allows easier transition through turns and a 5 fin option for use as a quad or a thruster. Its available from 5'8 to 6'4, RRP $785.
Surfculture now stocks a range of SURFTECH surfboards, We have MR super twins, SIMON ANDERSON Mollusc and AL MERRICK Flyers in store for you to check out. If anything else in the SURFTECH range catches your eye and if it's available, we can order it in! RRP $850
If you're still braving the cold and you haven't picked up a new steamer yet, We still have plenty of new season steamers on the racks that will keep you nice and toasty! So come up for a visit and we can fit you correctly and get you a suit that will keep you siked to surf during these colder months.
Lastly check out this footage of Timmy Curren shredding on a Channel Islands Motorboat. TIMMY CURRAN from Kyle MacLennan on Vimeo.
TIMMY CURRAN from Kyle MacLennan on Vimeo.


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We are very near to Sector Rocabella, 3km from El Chorro train station and 50km from Malaga Airport.
All our accommodations have Internet Wifi
ROCABELLA RESTAURANT: Complementing these 8 accommodations is Rocabella Restaurant where you can sample the typical cuisine of the area, tasty, traditional Spanish food in a warm welcoming family atmosphere. With WIFI INTERNET
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Basmati Rice help from a seasoned rice maker...
- mcel215 Dec 17, 2012 02:25 PM
I buy my white basmati rice from my local Indian Market. I always used Swad, and NEVER rinsed it. Put 1 cup of uncooked rice in a pan, with 1 & 1/2 cups of water. It came out perfectly every time. But the last time I was there, I bought a more expensive brand that begins with a "z". The owner (Indian), tells me to make sure I soak it for 1/2 hr. (I smile and leave, shaking my head yes)
So, tonight I soak my rice, because I think she must know better than me. And after I cook it the same way, it's like sticky rice. It's all stuck together?
Help please? I like my basmati to be a bit crunchy. This one is near awful. Should I just go back to no rinsing/soaking?
I think you should cook your rice the way you like it cooked as opposed to the way your grocer likes her's cooked.
I like my brown basmati rice crunchy also and this is what I do, I put a cup in a pot and cover it with water, and note how high the level is by putting my finger in and noting where the water hits it, i know this sounds crazy but I read it online somewhere, followed the directions and got the best rice ever, NOW after noting that, add water, swish the rice around, drain and do it again and again,,,three times rinsing!! I would swish it around , put it in a strainer, then back to the pot with more water, etc,,, lots of rinsing, After that, i added water to the right level , brought it to a boil, turned the heat down and simmered till done, it was great. No measuring . All that rinsing made an enormous difference
In general Indians do not eat undercooked rice.
So advice from and Indian will yield fully cooked rice.
Rinsing washes away and external starches and yields a fluffier rice.
I find soaking unnecessary unless the rice is very old and I only let it sit for 10-15 min.
I don't know how to guarantee crunchy/undercooked rice except to use less water. No one in my house likes crunchy rice, but I have never gotten basmati to be sticky, even if soaked.
I thought soaked rice requires less water than unsoaked rice. But I would rinse the rice thoroughly whether you soak it or not.
To be scientific about it, though, you should try cooking the new rice in the old way to see if there is something different about the brand, first.
The first poster is right - cook it the way *you* like it!
But the grocer is right in how it is "supposed" to be cooked. Basmati is rinsed/swished in several rounds of water, to get off all the starch. Indians want each grain separate. (So... sticky would be the opposite of their goal.)
Hi MCEL215,
Did you salt the soaking liquid? Persians will salt the soaking liquid. It's like brining. Then we boil it first before draining then steaming it. I'm not very sure but would imagine the Indian method should be similar. Honestly, I don't bother. A Japanese rice cooker does an amazing job for me with basmati rice (I buy Lal Qilla.). It comes out separate and perfectly cooked each and every time.
You should probably stick with the method you know and like, but this is how to cook basmati rice with the soaking method:
- Rinse the rice. Soak for 30 minutes. It's fine to soak for 2 or 3 hours if you have to, but any more than that and the rice will tend to crumble.
- Bring 1.5X water up to a boil in a pot with a good, tight lid, and add the drained rice. Let the water come up to a boil again, then reduce heat, cover and simmer from 1 to 5 minutes, depending on how well done you like your rice and how heavy your pot is (you'll be finishing the rice with residual heat, so the heaviness of the pot and the tightness of the lid make a significant difference to cooking time).
- Turn off the flame, but leave the pot on the burner. It should be done in 6 to 15 minutes (again, depends on how well done you like your rice and how well your pot retains heat).
- When the rice is done, remove from the heat, fluff and put into a serving vessel immediately. It will continue cooking a bit even after this, so when I make a very large quantity of rice, or a pulao or something else where there are more variables that might cause overcooking, I chill the serving vessel in the fridge or freezer so that it stops the cooking process more quickly.
I have heavy-bottomed pots with an OK fit on the lids and I usually simmer about 2 minutes and let sit about 8 minutes for nice separate grains (toothsome, but not crunchy). My mom has old, lightweight steel pots she bought at Wiebolt's in the 1970's, and she simmers 5 minutes and lets sit a full 15 minutes. It's all a matter of taste and the tools you're using. The best thing about this method though, is, once you get a feel of it, you can make huge or tiny amounts of rice and get it to come out perfectly every time.
Happy cooking, ninrn
Well, there is nothing wrong with soaking. It is just that (my understanding) soaking rice this long requires a different rice-to-water ratio. So if you have been having success with a 1:1.5 ratio without soaking, then you will need to use less water, presumably 1:1.3.
I like my Basmati rice fluffy and separated. I do rinse my Basmati rice to remove excess starch, but I do not soak my rice.
Was it Zafrani? I use either Zafrani or Royal, Depending on which one is cheaper. We Indians don't eat undercooked rice (at least not on purpose!) you rinse the rice in several changes of water, then soak it for 20-30 minutes. This makes the rice cook up fluffy and keeps the grains separate. Then you cook it. I use my rice cooker or a pot if I'm making a lot (like for Biriyani). For 2 cups rice, I would do 3.25 cups water on the stove and add more if needed towards the end.
re: boogiebaby
Yes boogiebaby, it is Zafrani brand.
re: boogiebaby
I also use Zafrani brand most of the time, and do as boogiebaby wrote, but I do salt the soaking water. Once drained, I fry the soaked rice in a bit of butter for 2-3 min to further reduce the moisture and to toast the grains a little, then add the water & cook.
re: pine time
Thanks pine time. I'll give your tips a try soon.
Thank you all for your advice.
My rice was always a bit undercooked, seperate and kind of crunchy. I have eaten rice in many Indian restaurants and mine comes out similar, not quite as fluffy though.
This rice was definately "soggy" and the grains broken and clumpy. And overcooked.
I will play around with times, less water and even try it the way I have been making it without rinsing also.
I'll check back and let you know how I make out.
I buy 'Neesa Select' Indian Basmati rice in 5KG bags.
I've tried not washing before going into the rice cooker. It turned out 'gummy/sticky. I always rinse a few times in room temp. water until the water stays clear. Perfect fluffy rice every time. Before I bought my cheap little rice cooker every time I made 'stove top' rice it was hit or miss. I like to mix things up when making cooked rice. Some times I'll add some 'ghee' and pinch of curry powder or maybe use orange juice instaed of water. You name it. I never salt the rice until it's cooked. If I was stranded on a desert island I'd take my rice cooker.
re: Puffin3
Thanks Puffin3, I'll give some more thought into a rice cooker. :)


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The meeting rooms Tragaluz (Skylight), the Tea Room and the Terrace are perfect places to hold business meetings, receptions, lunches and dinners in a warm, peaceful and complete privacy. The comfort of these function rooms, together with the exquisite service, ensures a successful event.
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Check the capacity of our meeting rooms.


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Scan result
Find a Conversation
|Mon, 09-24-2012 - 2:50pm
My endocrinologist called and said it appears that - maybe - there's "something on my spine". He talked with an oncologist who will call me and set up an appointment. He said I shouldn't be scared, that we just have to get to the bottom of this, but I'm scared.
Why can't anything be simple? Why couldn't I have gotten rid of the thyroid and be done with it all?
I still haven't told my sister or brother about this latest round of scans, and now this. I guess I'm waiting until I have something more definite to tell them.
I'll let you know more when I hear from the oncologist.
|Mon, 09-24-2012 - 10:35pm
Well, that report just sucks!! Don't be scared..yea, right!! Any of us would be "un-nerved" as Bunny puts it!! Glad we have Bunny here to guide you through these things with her experience!! Sure hope that oncologist calls fast and gets you in fast so you can get past this and ease your mind!! You know we're here for you and want the best for you!!
|Tue, 09-25-2012 - 8:57am


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Conor Friedersdorf brings an independent-minded perspective to dialogues on politics and culture.
|fast audio
On Friedersdorf, Elizabeth kicks things off by describing a project in which she photographs 30-year-old women. Conor expresses skepticism about the new theory that men today are more emotionally needy than before. Is everyone just freaking out about the end of gender norms? The diavloggers debate the government's proper role in combating obesity and consider portion size and deferred gratification. Conor inquires as to whether opposite-gender bathrooms should be used when they're empty and the bathroom to which you're assigned is full. Plus: Is wedding planning inherently sexist?
Conor and Peter try to make sense of QE3, the Federal Reserve's effort to kick-start the economy. Turning to the political fallout from the embassy attacks, Peter argues that Romney thinks about foreign policy like a management consultant. Though they both believe in the primacy of free speech, Conor isn't bothered by diplomats criticizing offensive videos. Peter talks about what Romney would actually do about health care if elected. If Romney wins the election, will the Tea Party ever trust him? Plus: Conor describes the album he'd love Jay-Z to make.
On a special crossover edition of Friedersdorf and The Posner Show, Conor and Sarah review the political conventions. Conor was disturbed by Joe Biden's bloodlust, but was impressed by Bill Clinton's speech. Turning a skeptical eye to the speeches by Michelle Obama and Ann Romney, Sarah and Conor discuss the folly of understanding a politician "as a person." They then talk about how the tension between neoconservatives and budget hawks at the Republican National Convention went unacknowledged. Conor explores the problems in Romney's plan for Medicare. Finally, Conor and Sarah lament that Democrats have abandoned the civil liberties positions they held in 2008.


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Articles tagged with: Data Protection
Blog, Human Rights »
By David Cook
It is difficult to have missed the hype surrounding Google Glass (referred to simply as "Glass"), not only because of its futuristic technological capabilities and design, but also the concerns it raises for an individual's Art 8 right to privacy.
Glass is, relatively speaking, inconspicuous. The camera enables the wearer, simply by voice command, to take photographs or record videos and upload these to the internet much more quickly and covertly than would be the case with a camera or smartphone. The difference between the technologies is three-fold:
It is …
Blog, Criminal, Human Rights »
By Lucy Corrin
Imagine you are a middle-aged man with a young family looking to change career to work as a primary school teacher. When you were 12 you took a chocolate bar from a shop. You learnt a salutary lesson and never repeated this isolated error of judgment. Is it right that your prospective employer should be told this? Well, whilst the Government thought your prospective employer should be forewarned, the Court of Appeal disagreed. The Court of Appeal, in R(T) & Others v Greater Manchester was critical of the …
Blog, Human Rights »
By Eduardo Ustaran
Going all the way to the Rio de la Plata to discuss the content of the future European data protection framework seems a little over the top, but the recent International Privacy Commissioners' Conference in Punta del Este, Uruguay provided a perfect forum as a neutral ground for a fierce policy debate. Surrounded by equally fierce winds and rain for added dramatic effect, regulators and other influential stakeholders in the privacy world locked horns in the most constructive possible way for three days to make the most of …
Blog, Human Rights »
By Eduardo Ustaran
Three years have gone by since the European Parliament shocked and awed everyone by tweaking the e-privacy directive and introducing the most controversial word in the data protection glossary – consent – in the provision that deals with Internet cookies.
The debate that followed immediately afterwards about the meaning of consent and whether it will ever be realistic to get everyone using the web to comprehend, consider and positively accept the use of cookies is still ongoing.
Much has been said, written and argued about this subject in the past …
Blog, Human Rights »
By Eduardo Ustaran
Obama gets it. Viviane Reding gets it. This is indeed a defining moment to get our public policies right in terms of global data protection and privacy. Ignore the human and social implications of the exploitation of personal data and we will lose forever the right to privacy and possibly our freedom. Be too overprotective with one of our greatest assets of our time and we will definitely block progress and prosperity. The stakes are really that high. That was the key underlying message of the recent EU-US …


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08.31.2012| By Allison Wolcott|
What I Did Last Summer: Shure 2012 Interns Tell All
Ah, summer internships. Filing, coffee runs, answering phones…oh wait, those were MY summer internships back in the late nineties. Summer internships at Shure are real jobs, and our recruiters travel far and wide to find the best college talent to fill them. Interns at Shure can expect to be an important part of their team, be it in engineering, IT, marketing, or wherever in the company they work. There's orientation, and then *BAM*, they jump into projects right away. In their free time, they hit the beaches, take in a Cubs game, rock out at …tagsAlexandria MonterrubioBen OlgercareersJian QiJohn LloydKevin NewhouseRaul HudemaRohan SahaiSarah BachSaul LiptonSummer Intern
08.30.2012| By Shure Notes|
"Crazy good": Videography, Wireless Receivers and the Shure UR5
By Shure Notes Editors Contributors: Keith Anderson, Videographer and Chris Lyons, Manager of Technical & Educational Communications at Shure Shure UR5 Wireless Diversity Receiver For the videographer who is either earning a living or bringing in some extra income by shooting video for weddings, events or the Internet – audio can present a challenge. You can't have a bride holding a microphone while exchanging rings or conventioneers tripping over cables in a convention hall where a manufacturer is shooting a new product introduction video. Enter wireless. How it Works Wireless systems for video have become …
08.30.2012| By Allison Wolcott|
Recent Reviews: Headphones, Mics & PSM
We've been testing our products to military specifications since World War II. So, when you see a new Shure product hit the shelves, you know it already survived a serious smackdown. Despite the confidence this gives us, we still get a little nervous when the first reviews roll in. (We …tagsAndy HongChurch Production MagazineKSM42Luke HarperMacLifeMark HolderNic VargusNolan RossiPost MagazinePSM 1000reviewsSRH1840SRH940TapeOpVideomakerVP89
08.27.2012| By Mike Lohman|
The Story of Shure: A Video
People always ask what it's really like to be a part of Shure, so we decided to make a video as an answer. It's not so much a historical timeline, but rather the story of who we are, what matters to us as a company, and where we're going. Personally, …
08.24.2012| By Richard Sandrok|
Gojira Will Not Be Stopped!
Fans of metal will know that recent circumstances involving Lamb Of God frontman Randy Blythe had led to the cancelation of their highly anticipated tour. It wasn't just Lamb Of God that had people excited; the line-up was to include the live version of Dethklok, the animated band from Adult Swim's Metalocalypse, and Gojira, one of the best up-and-coming metal bands in the world. I'm a bit opinionated when I say this, of course. They're new Shure endorsers. Gojira are not exactly a new band. They originally formed in the mid-1990s under the name Godzilla, …
08.24.2012| By Ryan Smith|
Jason Mraz & Christina Perri in Nashville
I knew I was in for a good show having listened to Jason's new CD Love Is A Four Letter Word. The Freedom Song starts off the CD and when the band kicks in, you can just imagine the live show. No more imagining, I was finally going to get to see a Jason Mraz show. First things first – I had to prepare questions for a short video interview with Jason. I like to research what other interviewers have recently asked an artist and then avoid those questions entirely…or at least rephrase them differently, …
08.24.2012| By Cory Lorentz|
The Top 5 Most Irritating Things About Gear Returning From A Loan
There are a few departments here at Shure that loan gear out to artists, engineers, television shows, movies, festivals… you name it. As you can imagine the Artist Relations department dabbles in this quite a bit. Typically we are trying to help out an artist traveling from overseas to tour here in the states or we find ourselves sending gear out for a band that is traveling with some guest musicians or we are simply letting a band demo some new gear before they commit to adding it to their live show. We are always …
08.22.2012| By Richard Sandrok|
Deftones and System Of A Down
I cannot recall a bigger buzz around the halls of Shure than in the months leading up to the Deftones/System Of A Down show. Both bands have large cult followings – a status that was evident by the chatter of my coworkers and mentions on my Facebook and Twitter accounts from the date the shows were announced. It was our honor to have System Of A Down as our Featured Artist of the Month for August. We gave two tickets each to the last two shows of the tour – Detroit and Chicago. I went …tagsAllstate ArenaBeta 58AChad OlechDeftoneshelical antennain ear monitorsKSM313Pasi HaraPSM 1000System Of A DownUHF-RWireless Workbench 6
08.20.2012| By Shure Notes|
Noise-Cancellation or Sound-Isolation: What's the Difference?
By: Shure Notes Editors, Contributor: Chris Lyons Noise cancelling headphones have become very popular in consumer markets over the past few years. Especially around the holidays, TV spots featuring de-stressed travelers in headphone Nirvana seem to dominate the airwaves. This has caused a little bit of confusion about the difference between sound isolation (as used in Shure earphones) and noise cancellation headphones like the ones you see advertised on television. Noise cancellation is an electronic process. It was originally developed to improve radio communications in noisy environments like aircraft cockpits. There's a microphone built into …tagsChris Lyonsearphonesheadphonesnoise cancellationpersonal listeningSalman AshraftShure Earphonessound isolation
08.17.2012| By Alexandria M|
Mumford & Sons with Dawes and The Last Post
For the last fifteen minutes I've been sitting at my desk staring at a blank document. To be honest, I'm not sure how to start off this blog post. Any words that come to mind do not seem quite good enough to describe what I have to share. Why? Two reasons… 1. Last night I saw Mumford & Sons with Dawes at the Chicago Theater and 2. This is my last day as the Shure Artist Relations Intern for the summer and therefore, my last blog post. But before the waterworks start, I must share …tagsDawesLena JuncajMarcus MumfordMike LohmanMumford & SonsNelson ArreguinTaylor GoldsmithThe Chicago Theater
08.17.2012| By Ryan Smith|
Memorable moments in Artist Relations.
After finishing my last post about how I got into Artist Relations, I thought about all of the wonderful moments I've been able to be a part of as a result of being in this job. Other associates often remind me to look back at what I have done so far and believe me – I still pinch myself every time I think about it. After all, I grew up wanting to be a part of this industry and now, it's my job to work within it! So I thought a bullet point format might …tagsAlison Krauss & Union StationArtist RelationsB.B. KingBeyonceBlackbird StudiosBlue Man GroupCheap TrickDark Horse RecordingDave WecklDestiny's ChildFoster The PeopleJason MrazJohn "JR" RobinsonLady GagaLeAnn RimesMaroon 5NAMMPaul NatkinSimon PhillipsSlashSlaughterSpinal TapThe Beach BoysThe Civil WarsThe Grammy'sThe WhoTony Iommi
08.13.2012| By Alexandria M|
Lollapalooza 2012
Lollapalooza… the one weekend out of the year when young music lovers roam the streets of Chicago in packs. It's not hard to spot them. They look like bouncing crayons in all their colorful attire happily showing off their wrist bands to the world. And this last weekend I am proud to say that for the first time I was able to join these Lollapaloozers in 72 hours of pure bliss. I woke up Friday, August 3rd with all the excitement of a child on Christmas morning. I immediately shot out of bed, got ready, …tagsBombay Bicycle ClubDr. DogFlorence + The MachineLollapaloozaMacklemoreRed Hot Chili PeppersThe Black KeysThe Head & The Heart


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Artist: Azuni
Title: Here You Come EP
Cat No: DPC 027-1
Format: 12″ / Download
Quotes: Here you Come has a rocking groove!! I'm all over it Hector Romero / really like Believe! deep fat beats.. Joris Voorn / here you come is hypnotyzing! Osunlade / Excellent single – will be getting fully rinsed. The Revenge / Believe got this old skool flavor and dubby at the same time…Will support this track on my radioshows and clubs DJ Franck Roger / cool vibes, believe is the joint for me Sneak / super! killer record. rough, heavy and with balls! exactly the way we like it. will play it fa lot! Trickski / perfect Milton Jackson / as always fantastic ep!! full support!! Catz N Dogz / Really into Here You Come. Killer track. Big support. Ashley Beedle
Info: Azuni are from Zurich and have recently released a great album entitled City Looks on Agnes' Sthlm Audio label, which introduced Azuni succesfully to the new house-catz. But the history of these two guys goes way back. Gianni Siravo was already active in the late 90's with his project Sequel and released music on Straight Ahead as well as on Sonar Kollektiv. Since he teamed up with Sven Lacoste they created a bootybouncin house groove which is stripped down and reduced to the max. After contributing the track "Nightshifter" to the Drumpoems 2 compilation they follow up with this awesome 12". Here you come starts with a hypnotic synth-groove and a real b-boy house beat which is hard to resist and takes you deeper into this original and fresh sound created by Azuni. Believe can't do no wrong. A great groove and a bouncy bassline just prove again that house-music shines in its rough and simple moments the most! It's a feeling!


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Becky Wright. Graphic design student. Nail obsessive. ASOS connoisseur. Loves old films. Likes shoes.
Have a gander at my creative blog: creating things the Wright way
Go gawk at my online behance portfolio
Has had the best night drinking a pot of tea, watching old films, doing coursework and doodling. Love evenings like this! The only thing missing was scones.


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AUSTINTOWN — There are no injuries to report from a morning school bus accident in Austintown.
The accident occurred just after 7 a.m. this morning on New Road between Cider Mill Crossing and Herons Boulevard.
The driver said the bus was right on the line at the edge of the road and then the bus just went into the ditch, Colleen Murphy, transportation director for Austintown schools, said.
The road's narrow edge "just sucked him right off of the road," Murphy said.
There were two students on the bus who were both unharmed.
The bus was retrieved from the ditch, but Murphy said she still unsure whether it can be used again.
The Mahoning County engineer's office was at the crash site, Murphy said. The Austintown Fire Department and police responded.
Other buses were able to pick up the remainder of students needing bus transportation.
"The drivers truly work together as a team especially when there is an emergency situation," Murphy said.
Many of the county roads in Mahoning County have poor and substandard shoulders with ditches too close to the road edge. This is the reason so many roads have pavement issues at the edges. A properly constructed road shoulder is essential for driving lane support. But, we simply mill and fill the roads because this allows the work to be done for less money and more miles of roads can be paved. This makes the politicians look good.
People want good roads, people want good parks, people want good schools, fire depts, and police depts. However when levies are up for vote, watch and see what happens.
With a more viable expanding local economy ; attention to infrastructure spending of all types must become a priority . A lot will need to be financed by borrowing , so municipalities need to get their balance sheets in order for this task .
This portion of New road is a "county road" supported by gas taxes and yearly registration tax. No special tax levy here as we give gubmint plenty but check out the Engineer's office laborers' benefits!
Was this the drivers first trip down this road? If not then the problem no doubt was inattention. Distracted driving is one of the chief causes of such accidents. There are are many instances everyday of drivers simply driving right off the road.


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Fall 2014 Enrollment OpeningsGES has four openings available for next year's kindergarten class and one opening each for third and fourth grades. See the enrollment page for details.
A free public school in Grand Marais, Minnesota that works from the principle of "one child at a time," where students learn based on their individual strengths, passions, needs and learning styles