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No one was injured when gunshots fired early Sunday hit a car and residence near 12th Street and 13th Avenue, Rock Island.
Officers were called to the area shortly after midnight, and no arrests had been made by Monday afternoon.
Rock Island Deputy Police Chief Jason Foy did not know how many shots were fired, but said it appeared the firearm used was a handgun.
An overnight incident report for the police department listed a 35-year-old female and a 42-year-old female as victims of the incident. Deputy Chief Foy said the women were not injured and are listed because they are the owners of the home and car that were hit.
Milan, IL Details
Spanish Corn with Chicken
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Welcum 2 a bl0g dedicatd to paint creeshuns of the Doktah Who nayture. Feel free 2 submit yor own masterpeeses nd hav fun. Wi mek our own and reboob others nd aksept submishuns.
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Listen up! See Gurl Try kicks off its new season on Monday!
Check out the above teaser trailer featuring our new host, Jamie!
(And yes, that's the same Jamie from our "Do It, Gurl" series! If you recognized her, then chances are you already know how awesome she is!)
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Defender desperate to make up for '09 disappointment.
If one Everton player has the right to feel he deserves a shot at an FA Cup final, it's Phil Jagielka.
In 2009, the defender went from semi-final matchwinner to cup final injury victim, a serious knee injury cruelly depriving the Player of the Season-in-waiting of the chance to take on Chelsea for the trophy.
It was the England man's coolly-struck penalty which set up the final-day meeting with Guus Hiddink's Londoners, but it proved to one his final acts of the campaign.
Fast-forward three years and the 29-year-old is hopeful of making a significant mark in the semis once again - even if patience may have to be a factor.
Jagielka has been sharing playing time in David Moyes' defence since sustaining another knee knock in January and understands Sylvain Distin and John Heitinga may be given the nod against Liverpool on Saturday.
"The memories that I have of playing in the semi-finals last time are up there with the best of my career," he said, reflecting on the spot kick which dispatched of heavy favourites Manchester United. "So it's nice to go back and it would be nice to play as big a part as I did last time. But I understand at the moment the boys have been doing really well, so I might have to bide my time and see how it goes.
"If my role at the moment is to give Johnny and Sylvain a rest for a game, it's not ideal for me, but we're all part of a squad which wants to do well and we all want to win a trophy. So whatever the manager sees fit, as long as the end result is what we want, we'll all be giving each other high fives and it will be irrelevant.
"I feel a little bit like I'm owed a final," he continued. "I've played in four semi-finals and I got through one but wasn't able to play in the final. I'm still lucky enough to have played those big occasions and they're fantastic enough on their own. But it would be nice to get through to a final and play in one. It would be even nicer obviously to win one."
Having experience the euphoria of toppling Sir Alex Ferguson's side in 2009, Jagielka knows what taking down Liverpool would mean this time around.
And should penalties be required - and should he be called upon - he'll be ready to shoulder the biggest responsibility once again.
"A semi-final is always massive but to play Liverpool is huge," he said. "We knew when the draw came out it was a huge incentive to go up to Sunderland and beat them and thankfully the lads played well and set up the tie of the round.
"Shootouts are hard. I'm not normally one who particularly likes to take one but the majority of the time your centre backs don't get changed so 120 minutes in you know you're likely to be one of the players left. I won't be jumping up and down saying pick me, pick me but if asked, as one of the elder statesmen, I'll have to step forward and try to score again."
- Previous Article Head-to-Head: Heitinga v Suarez
- Next Article What The Papers Say - April 12


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But what I do remember, which doesn't make the cut, is lying back on the jeep on a stretcher, pitch black, Shane having to, even though I don't believe it was in the script, cover me because obviously I'm injured so I can't cover myself, and explosions just kicking off all over the place around us. And we shot it for quite a while. It's in the cut, but quite slight in the cut. But I felt protected by him, genuinely, and I don't think it was just him being medic about it. He was having an eye towards my sort of well-being as well. He's like that, Shane.
-Rick Warden


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Here's another new vegan creamer to spice up your fall coffee or tea. It's full of cinnamon and apple all wrapped up in a creamy So Delicious Coconut Milk. It's cooked down thick and sweetened only with virtuous dates. This was my first recipe with So Delicious' new Culinary Coconut milk and I decided to […]
Easy Slow Cooker Date-Sweetened Apple Spice Creamer
October 21, 2013 · by · 1 Comment
Pumpkin Spice Cashew Creamer
October 14, 2013 · by · 8 Comments
Allyson Kramer shares my Vanilla Hazelnut Creamer and a Gingerbread Latte
September 13, 2013 · by · 5 Comments


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Viewing entries tagged with 'junior'
Bulldogs and Knights take out National Junior Rep Finals
RESULTS from today's National Finals of the Junior Reps, where New South Wales champions from Canterbury and Newcastle were dominant.
New South Wales Under 16's side announced
THE following players have today been selected to represent the NSW Under 16's v QLD Under 16's at SUNCORP Stadium on Wednesday 25th May 2011 prior to State of Origin One.
State Against State: Junior Finals
FOLLOWING on from the state Grand Finals last Saturday, this weekend it will be state against state in the Junior Rep Grand Finals at Leichhardt Oval!
Cowboys conduct Central Highlands school tour
NORTH Queensland Toyota Cowboys development manager Dean Payne is starting a five-day tour of the Queensland Central Highlands today.
Bulldogs and Knights take out NSWRL Junior Rep Honours
THE SG Ball and Harold Matthews competitions came to a close today with two big Grand Finals - and it was Newcastle and Canterbury who ran out winners!
NSWRL Junior Representative Grand Finals - Tomorrow!
GENERATION 'Next' will be on show tomorrow as the NSWRL 2011 Junior Representative competitions draw to a close as both the Harold Matthews and SG Ball Cup Grand Finals are decided at St Marys Leagues Stadium.
Cowboys calling for nominations for Laurie Spina shield
PLAYING on Dairy Farmers Stadium prior to the North Queensland Toyota Cowboys' NRL clash with the NZ Warriors will be one of the big thrills awaiting the teams who will play in the final of the Laurie Spina Shield on June 18.
QAS emerging Origin squad
NINE new players were today named in the QAS Emerging Origin squad that will be put through its paces by Academy Head Coach Wayne Bennett next month.
Junior Kangaroos fall prey to Junior Kiwis
THE ARL Junior Kangaroos have been beaten by the Junior Kiwis in Rotorua this afternoon after the New Zealanders spectacularly recovered from twenty points down at halftime to run out 36-20 winners.
Junior Kangaroos name squad for second test
COACH David Hamilton has today announced the Junior Kangaroos team to face the Junior Kiwis at the Rotorua International Stadium this coming Saturday.
Junior Kangaroos win opening tour game
THE ARL Junior Kangaroos have tonight won their opening tour match against the Junior Kiwis at Westpac Stadium in Wellington, running out 24-16 winners.
Young Kangaroos triumph over Kiwis
A double from Australian fullback Dane Gagai has helped the Junior Kangaroos to a 24-16 win over the Junior Kiwis at Westpac Stadium, Wellington.
Ben Jones has been named Junior Kangaroos captain
THE Sydney Roosters' Ben Jones has today been named captain of the ARL Junior Kangaroos for the upcoming two match series against the Junior Kiwis.
Final Junior Kangaroo squad announced
THE ARL have settled on their final junior kangaroos squad for two international fixtures against the junior kiwis
Australian Junior Kangaroos squad announced.
THE ARL Board has come together to select the Junior Kangaroos squad for two fixtures against the Junior Kiwis


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Kone Out Of Spurs Clash
But John Heitinga is ready to rejoin the squad.
Everton boss Roberto Martinez will be without Arouna Kone for the visit of Tottenham Hotspur after the striker suffered a setback in his recovery from a knee injury.
Dutch defender John Heitinga has returned to training following a muscle complaint however, meaning Antolin Alcaraz (hamstring) and Darron Gibson (knee) are the Spaniard's only other absentees.
Ivory Coast international Kone over-extended his knee after coming off the bench during last month's 2-1 win over Hull City and Martinez confessed the problem is worse than originally thought.
"We are a little bit worried about the knock that Arouna Kone picked up against Hull City," he said on Friday. "We had a bit of a setback. It's a little bit more serious than we first expected, so he won't be available for the squad.
"It [the severity of the injury] is something we need to find out over the next few days. We'll do a few tests and see how his knee is reacting."
Martinez also revealed how Gibson has been in good spirits following surgery on his ruptured anterior cruciate ligament, while fit-again full-back Tony Hibbert is impressing in his search for full match fitness.
"Darron Gibson has had a very good week straight after surgery, so it's been a real positive week and he's already on the road to recovery," said the Blues boss. "Tony is getting ready. He had 90 minutes in a practice game on Tuesday and that was a real positive. He's getting stronger in training and his experience is a real need for us to have him in the squad.
"I'm really looking forward to seeing him fulfil his fitness levels and then making sure he is available.
"He's been a really important player to have around, it's great to have him fully fit again and he's going to have a massive role this season."
Tickets for Sunday's game are still available. To buy, click here or call 0871 663 1878*.
Alternatively, visit the Park End box office at Goodison Park, Everton Two in Liverpool One or TicketQuarter in Queen Square.
- Previous Article Goal Of The Month: October
- Next Article Club Connector: Gary Lineker


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2. First Steps
Let's get started as simple as possible. We are going to demonstrate how to store, retrieve, update and delete instances of a single class that only contains primitive and String members. In our example this will be a Formula One (F1) pilot whose attributes are his name and the F1 points he has already gained this season.
First we create a class to hold our data. It looks like this:
Notice that this class does not contain any db4o-related code.
2.1. Opening the database
To access a db4o database file or create a new one, call Db4oEmbedded.openFile() and provide Db4oEmbedded.newConfiguration() as a configuration template and the path to your database file as the second parameter, to obtain an ObjectContainer instance. ObjectContainer represents "The Database", and will be your primary interface to db4o. Closing the ObjectContainer with the #close() method will close the database file and release all resources associated with it.
DB4OFILENAME is just a string value representing any filename. If the file with this name already exists, it will be opened as db4o database, otherwise a new db4o database will be created.
For the following examples we will assume that our environment takes care of opening and closing the ObjectContainer automagically, and stores the reference in a variable named 'db'.
2.2. Storing objects
To store an object, we simply call #store() on our database, passing any object as a parameter.
We'll need a second pilot, too.
2.3. Retrieving objects
The easiest way to see the content of our database is to use Object Manager Enterprise, which will be introduced in the next chapter . For now let's continue with the API overview and learn how to build db4o queries.
db4o supplies several different querying systems, Query by Example (QBE), , Native Queries (NQ) and the SODA Query API (SODA). In this first example we will introduce QBE. Once you are familiar with storing objects, we encourage you to use Native Queries .
When using Query-By-Example, you create a prototypical object for db4o to use as an example of what you wish to retrieve. db4o will retrieve all objects of the given type that contain the same (non-default) field values as the example. The results will be returned as an ObjectSet instance. We will use a convenience method #listResult() to display the contents of our result ObjectSet :
To retrieve all pilots from our database, we provide an 'empty' prototype:
Note that we specify 0 points, but our results were not constrained to only those Pilots with 0 points; 0 is the default value for int fields.
db4o also supplies a shortcut to retrieve all instances of a class:
For JDK 5 there also is a generics shortcut, using the query method:
To query for a pilot by name:
And to query for Pilots with a specific number of points:
Of course there's much more to db4o queries. They will be covered in more depth in later chapters.
2.4. Updating objects
Updating objects is just as easy as storing them. In fact, you use the same #store() method to update your objects: just call #store() again after modifying any object.
Notice that we query for the object first. This is an importaint point. When you call #store() to modify a stored object, if the object is not 'known' (having been previously stored or retrieved during the current session), db4o will insert a new object. db4o does this because it does not automatically match up objects to be stored, with objects previously stored. It assumes you are inserting a second object which happens to have the same field values.
To make sure you've updated the pilot, please return to any of the retrieval examples above and run them again.
2.5. Deleting objects
Objects are removed from the database using the #delete() method.
Let's delete the other one, too.
Please check the deletion with the retrieval examples above.
As with updating objects, the object to be deleted has to be 'known' to db4o. It is not sufficient to provide a prototype object with the same field values.
2.6. Conclusion
That was easy, wasn't it? We have stored, retrieved, updated and deleted objects with a few lines of code. Now you are probably interested to see how the database looks like. Let's have a look using db4o graphical tool - Object Manager in the next chapter .
2.7. Full source


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A good and interesting rice dish. Served with homemade tamales. Ours came out a bit spicy. I'm undecided on whether I will make again.
Green Rice
"This is one of my favorite recipes to make because it's always well received. It has a wonderful aroma that envelops the house." -Arundathi Krishna, San Mateo, CA
Yield: 4 servings (serving size: 1 cup)
More From Cooking Light
Nutritional Information
Amount per serving
- Calories: 243
- Calories from fat: 9%
- Fat: 2.5g
- Saturated fat: 0.3g
- Monounsaturated fat: 1.3g
- Polyunsaturated fat: 0.6g
- Protein: 4.5g
- Carbohydrate: 55.1g
- Fiber: 4.7g
- Cholesterol: 0.0mg
- Iron: 2.8mg
- Sodium: 311mg
- Calcium: 28mg
- 4 cups plus 2 tablespoons water, divided
- 1 cup basmati rice
- 1 cup chopped fresh cilantro
- 2 poblano chiles, seeded and coarsely chopped
- 1 1/2 teaspoons olive oil
- 1 cup finely chopped onion
- 1/2 cup chopped green bell pepper
- 1/4 cup chopped green onions
- 1 garlic clove, minced
- 1/2 teaspoon salt
- Combine 2 cups water and rice; let stand 30 minutes. Drain well.
- Place 2 tablespoons of water, fresh cilantro, and poblanos in a blender or food processor; process until smooth.
- Heat oil in Dutch oven over medium-high heat. Add onion, bell pepper, green onions, and garlic; sauté 3 minutes. Add poblano mixture; sauté 2 minutes. Stir in rice, 2 cups water, and salt; bring to a boil. Cover, reduce heat, and simmer 15 minutes or until liquid is absorbed.
My Notes
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Green Rice Recipe at a Glance
- COURSE: Appetizers, Side Dishes/Vegetables
- MAIN INGREDIENT: Rice/Grains
- DIETARY CONSIDERATION: Low Cholesterol, Low Fat, Low Saturated Fat
- PUBLICATION: Cooking Light
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"Bring the Noise 2011"Deadline: 2011/03/06
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Response to residential time-of-use electricity rates : How transferable are the findings?
AbstractNo abstract is available for this item.
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Bibliographic InfoArticle provided by Elsevier in its journal Journal of Econometrics.
Volume (Year): 26 (1984)
Issue (Month): 1-2 ()
Pages: 141-177
Contact details of provider:
Web page: http://www.elsevier.com/locate/jeconom
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Cited by:
- Henley, Andrew & Peirson, John, 1998. "Residential energy demand and the interaction of price and temperature: British experimental evidence," Energy Economics, Elsevier, vol. 20(2), pages 157-171, April.
- Mostafa Baladi, S. & Herriges, Joseph A. & Sweeney, Thomas J., 1998.
"Residential response to voluntary time-of-use electricity rates,"
Resource and Energy Economics,
Elsevier, vol. 20(3), pages 225-244, September.
- Herriges, Joseph A. & Baladi, S. & Sweeney, T., 1998. "Residential Response to Voluntary Time-Of-Use Electricity Rates," Staff General Research Papers 1233, Iowa State University, Department of Economics.
- Henley, A & Peirson , J, .
"Energy Pricing and Temperature Interaction: British Experimental Evidence,"
Discussion Papers
9616, Department of Economics, University of Wales, Aberystwyth.
- Henley, A & Peirson , J, 1996. "Energy Pricing and Temperature Interaction: British Experimental Evidence," Working Papers 96-16, University of Wales, Aberystwyth, Department of Economics.
- Mountain, Dean C. & Lawson, Evelyn L., 1995. "Some initial evidence of Canadian responsiveness to time-of-use electricity rates: Detailed daily and monthly analysis," Resource and Energy Economics, Elsevier, vol. 17(2), pages 189-212, August.
- Torriti, Jacopo, 2013. "The significance of occupancy steadiness in residential consumer response to Time-of-Use pricing: Evidence from a stochastic adjustment model," Utilities Policy, Elsevier, Elsevier, vol. 27(C), pages 49-56.
- Adela Conchado & Pedro Linares, 2010. "The Economic Impact of Demand-Response Programs on Power Systems. A survey of the State of the Art," Working Papers 02-2010, Economics for Energy.
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2012 Solo 401k contribution limit is $50,000 ($55,500 if age 50+ due to a "catch-up" provision).
Tax free loans are permitted with a Solo 401k plan. Loans are permitted up to 1/2 of the total value of the Solo 401k up to a maximum of $50,000.
Roth 401k - There is an option to make Roth 401k contributions with the salary deferral portion of the Solo 401k. Contributions into a Solo Roth
401k are not tax deductible, but withdrawals are tax free after age 59 ½.
Potentially greater administrative responsibilities and administrative fees compared to a SEP IRA.
The term Solo 401k is commonly used to refer to the Individual 401k (also known as a Self Employed 401k, Personal 401k, Uni-k and Single k).
The SEP IRA and Solo 401k are popular because both plans have high contribution limits and have completely discretionary annual funding
requirements. In 2012 a SEP IRA has a maximum contribution limit of $50,000 and a Solo 401k has a contribution limit of $50,000 ($55,500 if age
A SEP IRA is easier to setup and has less administrative costs than a Solo 401k, however a Solo 401k may allow a greater contribution at the
same income level due to the way the contribution is calculated.
After tax Roth contributions can be made into a Solo 401k. Roth 401k contributions are not tax deductible, but are received tax free when withdrawn
after age 59 ½. SEP IRA contributions can only be made pre-tax and does not have a Roth option.
Another important distinction between these self employed retirement plans is a Solo 401k has a loan provision. IRS rules do not allow loans with a
SEP IRA. Solo 401k loans are permitted up to 50% of the total 401k value with a $50,000 maximum.
|Individual (SOLO) 401k
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Reviews and Comments


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GreatSchools Rating
Teacher quality
Principal leadership
Parent involvement
Academic programs are strong, and as well as the availbility of music program, arts sports and other extracurricular activities. Parent involvment and volunteer opportunities are strong.
Turtle Rock is a great school. But At times I feel that they push the students to be very competative and it can be damaging to young egos. Also, they currently are having PTA meetings during the day, which is difficult for working parents to be able to participate. Great school with high standards, but seem to be very concerned about thier ratings than the actual place a student might be at. Also, it can be very difficult working with the office.
it's an excellent school. the teacher is knowledgable.
Great 6th Grade Teachers. Excellent Arts Program, and a gret English Program.
Excellent academic school with a much more diverse population than Bonita Canyon due to the UCI demographics. Fantastic elementary school experience for all my children with a great academic preparation for University High School.
This school is highly academic. Very involved parents and teachers. Wonderful, challenging teachers.
Test scores and conformity come first, creativity and individual growth a distant second at this school. This is a highly structured, top-down environment, and is unlikely to suit a child with a creative mind or an independent spirit.
Good School. Lots of activies for kids.
My son attended K - 4th grade at TurtleRock Elementary. His experience here was excellent. I was extremely impressed with the teachers and their interest in the kids. Cory was challenged yet had fun.
My son attended K - 4th grade at TurtleRock Elementary. His experience here was excellent. I was extremely impressed with the teachers and their interest in the kids. Cory was challenged yet had fun.
Great community and teachers. Love it!
My children love being in this school. They can't wait to go to school in the morning. Turtle Rock is a place for learning and for playing. It is a happy place for them. I am very proud of what Turtle Rock has achieved!
I am a teacher at this school and I think this school is the greatest. All of our teachers are so qualified and wonderful and we are lucky to have such supportive parents. Also, we have the best students! Turtle Rock is a great place to learn!
Fantastic area. The district emphasis on quality shows, with this school being one of the very best in an excellent school district.
Community ratings and reviews do not represent the views of GreatSchools nor does GreatSchools check their accuracy or verify the reviewers' identities. Use your discretion when evaluating these reviews.
The Community Rating is the school's average rating from its community members (e.g., parents, students, and school staff). The highest possible rating is five stars; the lowest is one star.
5151 Amalfi Drive
Irvine, CA 92603
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Guy's 'Friends' Push Him Into Water with Shark
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It's been a weekend of destruction in Vermont. Areas in the Northeast Kingdom saw substantial amounts of damage. Including in Glover, where residents are now working on putting the pieces back together.
This summer has been one of devastating storms. Saturday, the Northeast Kingdom town of Glover experienced yet another round of heavy winds and rain.
"I had a calf blow in the air. We found it. She's in rough shape, might make it," said farmer Brandon Tanner.
Tanner was out mowing the hay when the storm rolled in. Moments later, he found himself in the middle of it as it blew down trees around him. He still wasn't prepared for the damage waiting for him back at home.
"When I got back to the barn and I had two leveled barns and equipment flying everywhere," Tanner said. "I had some cows hit in the head, punctured eyes. One swimming in the manure pit."
"We had stuff blow all the way, probably the length of about two football fields, all the way across that hay field," said Glover resident David Perrigo.
One of Perrigo's prized possessions, a tumbled apple tree, is now laying in the yard.
"The old apple tree with the red swing that everyone's known for years and years won't be there anymore," Perrigo said. "We'll have all the family up this week. Get a little help to do the clean up and what not."
As Perrigo and Tanner wait for family to arrive to help out, Hal Parker won't be having any guests any time soon at his vacation home on Daniel's Pond. He'll be cleaning up the mess for awhile.
Residents say they hope to have everything back to normal as soon as possible. But with the unexpected storms so far this summer, many are concerned of possibly more on the horizon.
"It came very fast, couldn't prepare for it. The sky turned black, then it just hit us," Parker said.
Within a matter of minutes, the storm had passed, downing 70-year-old trees and leaving debris everywhere.
At the height of this weekend's storms, 10,000 customers lost power. Sunday evening, about 1,300 still needed to have power restored.
PO Box 4508
Burlington, VT 05406-4508
Primary Phone: 802-652-6300
Primary email: email@example.com


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Posts Tagged 'pumpkin'
Caramel Frosted Pumpkin Mini Cakes
One of my favorite bands, Paramore, is playing in Nashville tonight. Originally when I had planned on going out of town for Thanksgiving, I was going to stop and see that show on my way out. Unfortunately that is no longer my plan as I decided to stay put and save money. I did see them with No Doubt a couple years back and with Jimmy Eat World before that so it's not too heart breaking – except that they are the headliners this time. You better believe I will be cooking dinner tonight while dancing around to their music, pretending I'm there. Not that that's different from a normal day in my kitchen…
In other news, today is National Cake Day! With Thanksgiving nearly upon us I am throwing as much pumpkin at you as I possibly can, including these mini cakes. These individual cakes are made by cutting rounds from a thin sheet cake. The rounds are layered and frosted with a caramel cream cheese frosting and then topping with caramel sauce and candied pecans, resulting in eyegasms. Who wouldn't want their own personal mini cake?
You can use the leftover cake scraps to make cake balls or if you'd prefer to avoid scraps, make these into cupcakes instead.
One year ago: Arugula Pesto Pasta
Three years ago: Caramel Apple Pie
Read the rest of this entry »
Thanksgiving Dinner for Two
Normally for Single Serving Sunday I try to share recipes that only make one serving, but with the upcoming Thanksgiving feast I decided to do something special – a Thanksgiving meal that serves two. Many recipes for Thanksgiving produce a magnitude of servings, but what about the people out there only cooking for two, or four? This menu I have prepared easily serves 2 with leftovers. Because who doesn't want leftovers from Thanksgiving? That being said, the turkey could serve four but if you have hearty eaters you may want to double the sides.
This dinner consists of a slow cooker turkey tenderloin with gravy, Greek yogurt-rosemary rolls, bagel-bacon stuffing, roasted brussels, twice baked sweet potatoes, cranberry-pomegranate sauce, and pumpkin crème brulee for dessert. Take a moment to be jealous.
My turkey tenderloin came out so juicy and flavorful that it will be hard to convince me to cook a whole turkey in the future. It literally fell apart when I lifted it out of the pot. By using a slow cooker I was also able to do whatever the heck I wanted in the oven, which is a huge perk for those of us with only one oven (one day I hope to be spoiled with a double oven). Even the gravy was amazing after cooking in all those delicious juices.
As you are aware, I have a habit of adding Greek yogurt to anything I possibly can so it shouldn't be a surprise that it shows up here in dinner rolls. The rosemary really sold me on these rolls. If you don't like rosemary, please substitute for another herb because they will rock your world with their subtle herby-ness. You can also prep these the day beforehand and refrigerate before the last rise. The next day, take them out of the fridge about 30 minutes before you want to bake them.
Then there's the stuffing. I've seen stuffing made with all types of bread but this was the first recipe I had seen using bagels. I originally set aside two corn muffins for stuffing, but those were thrown into the freezer once I discovered I could use a bagel instead. I freaking love bagels! And I was not disappointed by the trade-off, especially since there was bacon involved.
For a green side I chose brussels sprouts. Only a couple Thanksgivings ago I discovered that I no longer hated them and actually became obsessed. As a result, they are nostalgic to me at this time of year. Just a simple roasting and a drizzle of balsamic is all they needed.
Growing up we usually had both regular mashed potatoes and mashed sweet potatoes but knew I would burst if I tried to add both onto this already long lineup. I went with a twice baked sweet potato that is topped with pecans and coconut. Although it is less sweet than a marshmallow topping, it has a crunchier topping that will make you forget about those puffy white things (no offense marshmallows, I still love you).
No Thanksgiving dinner is complete without some cranberry sauce. This version uses pomegranate juice for a more complex flavor. This can be made the day beforehand or even a few days before to minimize the amount of work you have to do on the big day. But if you do have to whip it up the same day, rest assured that it will only take 20 minutes.
Of course, once you've stuffed your face you'll still find room for dessert, right? Especially for pumpkin crème brulee. I know you may initially think it's a crime to not have pumpkin pie but it's basically pumpkin pie and crème brulee all in one. Are you really going to be upset by having both?
Now for some tips on how I timed everything in order to be hot and ready all at the same time. An hour before turkey is done cooking (mine only took 4 hours), take rolls out of fridge (if prepared the night before), toast the bagel for stuffing, and prep the brussels sprouts. Bake the stuffing and brussels at the same time and with 20 minutes of cook time remaining, add the sweet potatoes and rolls to the oven. At that time, remove the turkey from the slow cooker and prepare the gravy. Slice up the turkey and serve! Then once your belly has digested a little to make room for dessert, torch the creme brulee just before you're ready to dig in.
One year ago: Buckeye Cupcakes
Two years ago: Apple Blackberry Pie
Three years ago: Cranberry Sauce
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Stuffed Shells with Pumpkin Sage Cream Sauce
With my dissertation behind me and only 21 days until I graduate and get hooded for my Ph.D. you'd think I would be care-free and excited. Not so much, more like the same old stress and anxious. I am still working on a couple last experiments per reviewers comments on my paper, job hunting, and worrying about what I am going to do if I don't have a job lined up by the end of January when my lease runs out. With any luck that last item won't become a reality, but in the meantime it's a good time for some comfort food.
Stuffed shells are great comfort food. Those big shells hug in their cheesy goodness of a filling while being wrapped up in a warm blanket of sauce. Sounds like the life, doesn't it? This sauce happens to be extra special because it is a pumpkin alfredo sauce with sage. Now wait, don't get discouraged thinking you have to make your own alfredo sauce (but you can if you want). This recipe uses a premade jar of alfredo mixed up with pumpkin puree and a couple other flavor additions to create a great fall pasta dish.
One year ago: Individual Baked Pumpkin Oatmeal
Two years ago: Thanksgiving Recipe Roundup
Three years ago: Veggie Lasagna
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Pumpkin Baklava Bars
After making peanut butter baklava bars I immediately knew I wanted to try it out with pumpkin for the holidays. As much as I loved the peanut butter version, how could it not be just as good if not better with pumpkin? With the cinnamon, honey, and nuts floating around in there it was meant to be.
The result is what I imagine would happen if pumpkin pie and baklava got together and made babies. With a sugar cookie base, pumpkin-walnut filling, crispy fillo topping and completely coated in honey, it's two deserts in one. As a bonus it's easy to make and therefore should definitely make it for your upcoming festive gatherings.
As far as the job search is going, I have applied to many, but no hooks just yet. I just have to keep applying for those which interest me and I am qualified for and hope for the best. I probably should track down contact numbers to HR or whoever I can find to inquire about my applications. Unfortunately several to which I have applied explicitly say that calls are not welcome. Ugh… Thankfully I have a couple little projects to fiddle with in the lab to keep me busy in the meantime and will be resubmitting my paper now that I have finished addressing reviewers comments. Having that paper in press will definitely improve my CV!
One year ago: Baked Purple Sweet Potato Doughnuts with Marshmallow Glaze
Two years ago: Gluten-Free Cake Batter Pancakes
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Chocolate Pumpkin Pancakes
Not only is it another Secret Recipe Club reveal day, but it's also National Chocolate Day! As a result, my recipe selection for today from Vintage Kitchen Notes involves chocolate. But before I talk about that, you should check out some of Paula's other recipes such as Grilled Eggplants with Honey and Spices, Brown Sugar Cheesecake, and these festive White Chocolate Dulde de Leche Ghosts. I also almost made her Chocolate Walnut Sheet cake for today but I hadn't treated myself to pancakes in awhile.
I ended up choosing her recipe for chocolate pumpkin pancakes. The original recipe used chocolate chips, but I decided to mix in cocoa powder instead to spread the chocolate throughout the pancakes. The chocolate flavor wasn't as pronounced, but I liked the added flavor in addition to the pumpkin and cinnamon. And I went ahead and sprinkled some mini chocolate chips on top anyway. It's a fall breakfast treat!
Two years ago: Halloween Brownie Roll Out Cookie Sandwiches
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Sea Salt Pumpkin Peanut Butter Cups and a Bar & Bean Giveaway
Did you know that this coming Monday, October 28th, is National Chocolate Day? I'm here to tell you to not just celebrate it with any old chocolate, but try something new. Bar & Bean is an online marketplace for small-batch craft chocolate (less than 250 tons annually). The makers of the chocolates they stock are working to reintroduce and redefine a flavor that has been dominated by large producers.
I was sent Bar & Bean's Baker's Set which is a mix of 5 craft chocolate bars:
(1) Ritual Chocolate – based in Denver, CO and started by 2 individuals: Robbie and Anna. Balao 75% Cacao – characterized by citrus and nutty notes. Only 2 ingredients: cacao and sugar.
(2) Poco Dolce – based in San Francisco, CA and started by Kathy Wiley. "Poco Dolce" literally translates from Italian as "not too sweet", which aligns with the company's mission of staying on the "savory side of sweet". Bittersweet with Sea Salt – light sprinkling of Grey Sea Salt.
(3 & 4) Escazu – based in Raleigh, NC and started by Hallot and Danielle. Uses an antique roaster and stone grinder to make chocolate in a more traditional method to bring out flavor complexity. Chipotle Chili & Vanilla – 74% dark chocolate that is complemented with a spicy kick of chipotle chili. Pumpkin Seed and Guajillo Chili – 73% dark chocoloate with roasted pumpkin seeds and guajillo chili.
(5) Dick Taylor – based in Aracta, CA and started by two college buddies Adam Dick and Dustin Taylor. Dick Taylor uses only organic cacao and organic cane sugar in its bars. They roast their beans in their modified Royal #5 coffee bean roaster. Aged for at least 2-4 weeks to further develop and stabilize flavor. Fleur de Sel – 74% Dominican Republic with hand harvested sea salt.
The first bar I tried was the Escazu Pumpkin Seed and Guajillo Chili Dark Chocolate bar, and it inspired me to incorporate pumpkin seeds into the pumpkin peanut butter cups I had been planning to make for today, which is National Pumpkin Day (and also the usual PB+Choc Saturday). Then I went after the two sea salt bars because that's one of my favorite things in special chocolate. And as a result the pumpkin peanut butter cup with pepitas then got a sprinkle of sea salt on top as well!
Unfortunately, I did not leave enough leftover to make these cups completely out of the chocolate I was sent, but the recipe was inspired by all the craft chocolate I got to try. These little cups are the perfect combination of pumpkin, chocolate, and peanut butter in order to fully celebrate. To make the celebration even better, be sure to find the Rafflecopter widget after saving the recipe in order to enter to win your own set of craft chocolate.
As for the PB+Choc portion of today's celebration, today Ohio State plays Penn State which means many people in my life are enemies on this day. Hopefully it will only last the day. Penn State is coming back after a 4OT win against Michigan, so it should be a really good game. They are still not eligible to play in the B1G or National championship games, so it's really to the benefit of the conference as a whole if we win O:-). However, I don't particularly want to go to the Championship game either because as good as I do believe we are, I am not sure we are at the same level as Alabama or Oregon. As much as I hate to admit it.
Two years ago: Butternut Squash Mac and Cheese with Caramelized Onions, Bacon, and Apple
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Chocolate Pumpkin Cupcakes with Cinnamon Buttercream
If you recall, last week I posted a savory recipe for a Chicken & Sweet Potato Potpie using the Baker's Secret 9-inch pie pan. Today I am sharing a sweet recipe using their muffin/cupcake pans because who doesn't enjoy a good festive cupcake?
The combination of pumpkin and chocolate is not visited enough, in my opinion. I discovered the joy of those two flavors mixed together when I made the Pumpkin Kissed Gingerbread Brownies. This time they come together in the form of a cupcake, with a cinnamon buttercream. Complete with fall leaves sprinkles.
Don't forget to enter to win your own Baker's secret pie pan and muffin pan by clicking HERE and using the Rafflecopter widget at the bottom of the post. Giveaway ends tonight!
Two years ago: Stuffed Flank Steak with Potato Cakes and Amaretto Chocolate Cheesecake
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Pumpkin Spice Brownies
Last fall I saw a few bloggers post about two-ingredient pumpkin brownies, which only requires a box of brownie mix and a can of pumpkin. I was skeptical but finally decided to try it out this year except I added in a couple more ingredients such as cinnamon, frosting and pumpkin spice M&M's I found at Target.
Be warned, if you do not like dense fudgy brownies these are not for you. But if you do then stick around and stay awhile! As you can see from the pictures of these brownies, they are so fudgy that they actually look like fudge. I also think that the additions made them taste a little more like pumpkin than they would have otherwise. They really are a great way to make a slightly healthier Halloween treat!
Speaking of Halloween, while snapping photos of these brownies on my porch I spied a huge spider in the top corner of my porch, resting on an approximately 3-foot wide web spanning from the roof to the handrail. Commence freak out! His/her abdomen was about the size of a nickel. Add a head and legs and you'll understand why I quickly snapped these photos and ran inside.
No I did not attempt to kill it, because when it comes to bugs, I don't like feeling when I kill them and when they are that big that's exactly what will happen. Besides, the spider was basically floating in the air on the web so it would've been hard to squash without catching it first. Who has a flame thrower I can borrow? I don't think my kitchen torch will cut it.
In the meantime, thanks for the Halloween decorations?
Two years ago: Peanut Butter Hot Chocolate with Oreo Crumbs
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And I don't care if you see this
and don't want to talk to me ever again or hang out ever again, but there's not a thing in the world I wouldn't do to go back and undo everything and still be with you. There's not a thing I wouldn't do to go back to the time when you still loved me back, before I was replaced. I don't care how happy she'll make you. I know there's no girl who could treat you like I could. I know that there's no girl that knows you like I do, nor will there ever be.


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Just wondered if anyone has a way of removing and preventing storage of MP3s that are clearly copyrighted without stopping Audacity projects and legit MP3s some departments have purchased.
Even a slightly automated solution would be nice - our full backup is taking ages to run!
*searches /students/homes/ for *.mp3*


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Spanking and Punishment Website Directory
Spanking and Punishment. The best caning, OTK, schoolgirl, paddling, birching, humiliation adult spanking websites. Spanking videos, spanking stories and pics. Free spanking videos. Spanking personals, and spanking implements.
I am a legal adult, with an interest in the practice of
Enter Spanking and Punishment Website Directory
PARENTS! Use one of these services to prevent children from accessing adult oriented web sites:


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Explore Outdoor Stewardship
Jarvis Bird Sanctuary Workday
Saturday, January 12
9 a.m. – 2 p.m.
Jarvis Bird Sanctuary – 3550 N. Lake Shore Drive
Come dressed for the weather, rain, snow or shine to help clear brush and remove invasive species to restore this natural area which provides essential habitat for birds to rest and feed during migration.
Meet at the shed near the southeast corner of the parking lot. For more information or questions, contact email@example.com.


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This week's show came about in the best possible way — while browsing illustrated books about classic literature at a quaint children's book shop in Minneapolis (The Wild Rumpus). I pitched the brilliant folklorist Maria Tatar as a guest who could talk about why all these timeless stories are infusing our culture in fresh ways these days. The popularity of Game of Thrones and The Vampire Diaries is a testament to the great, inventive work being done.
The result? "The Great Cauldron of Story: Why Fairy Tales Are for Adults Again."
Fairy tales don't only belong to the domain of childhood. These stories' overt themes are threaded throughout hit TV series like True Blood, Grimm, and Once Upon a Time too. These stories survive, says Maria Tatar, by adapting across cultures and history. They are carriers of the plots we endlessly re-work in the narratives of our lives — helping us work through things like fear and hope.
I think you're going to dig this conversation. If so, spread the word: reblog, tweet, post on your own site, you name it.
~Trent Gilliss, senior editor
A fascinating look at fairy tales and how we tell them from the folklorist Maria Tatar. If you're at all interested in how fairy tales are being adapted today in television, movies, and elsewhere, give it a listen. Tatar discusses how fairy tales have moved across time and through different cultures, why they are popular now, and what they say about us, the people who continue to tell them. Really interesting stuff!


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Seretide 50, 125, 250 Evohaler
Last Updated on eMC 07-May-2013 View changes | Allen & Hanburys Ltd Contact details
- 1. Name of the medicinal product
- 2. Qualitative and quantitative composition
- 3. Pharmaceutical form
- 4. Clinical particulars
- 4.1 Therapeutic indications
- 4.2 Posology and method of administration
- 4.3 Contraindications
- 4.4 Special warnings and precautions for use
- 4.5 Interaction with other medicinal products and other forms of interaction
- 4.6 Fertility, pregnancy and lactation
- 4.7 Effects on ability to drive and use machines
- 4.8 Undesirable effects
- 4.9 Overdose
- 5. Pharmacological properties
- 5.1 Pharmacodynamic properties
- 5.2 Pharmacokinetic properties
- 5.3 Preclinical safety data
- 6. Pharmaceutical particulars
- 6.1 List of excipients
- 6.2 Incompatibilities
- 6.3 Shelf life
- 6.4 Special precautions for storage
- 6.5 Nature and contents of container
- 6.6 Special precautions for disposal and other handling
- 7. Marketing authorisation holder
- 8. Marketing authorisation number(s)
- 9. Date of first authorisation/renewal of the authorisation
- 10. Date of revision of the text
Recommended Doses:Adults and adolescents 12 years and older:- Two inhalations of 25 micrograms salmeterol and 50 micrograms fluticasone propionate twice daily.or- Two inhalations of 25 micrograms salmeterol and 125 micrograms fluticasone propionate twice daily.or- Two inhalations of 25 micrograms salmeterol and 250 micrograms fluticasone propionate twice daily.A short term trial of Seretide may be considered as initial maintenance therapy in adults or adolescents with moderate persistent asthma (defined as patients with daily symptoms, daily rescue use and moderate to severe airflow limitation) for whom rapid control of asthma is essential. In these cases, the recommended initial dose is two inhalations of 25 micrograms salmeterol and 50 micrograms fluticasone propionate twice daily. Once control of asthma is attained treatment should be reviewed and consideration given as to whether patients should be stepped down to an inhaled corticosteroid alone. Regular review of patients as treatment is stepped down is important. A clear benefit has not been shown as compared to inhaled fluticasone propionate alone used as initial maintenance therapy when one or two of the criteria of severity are missing. In general inhaled corticosteroids remain the first line treatment for most patients. Seretide is not intended for the initial management of mild asthma. Seretide 25 micrograms /50 micrograms strength is not appropriate in adults and children with severe asthma; it is recommended to establish the appropriate dosage of inhaled corticosteroid before any fixed combination can be used in patients with severe asthma. Children 4 years and older:- Two inhalations of 25 micrograms salmeterol and 50 micrograms fluticasone propionate twice daily. The maximum licensed dose of fluticasone propionate delivered by Seretide inhaler in children is 100 microgram twice daily. There are no data available for use of Seretide inhaler in children aged under 4 years.Children <12 years old may have difficulties synchronising aerosol actuation with inspiration of breath. Use of a spacer device with Seretide inhaler is recommended in patients who have, or are likely to have difficulties to coordinate actuation with inspiration. A recent clinical study has shown that paediatric patients using a spacer achieved exposure similar to adults not using spacer and paediatric patients using Diskus, confirming that spacers compensate for poor inhaler technique (see Section 5.2). Either the Volumatic or AeroChamber Plus spacer device can be used (depending on National Guidance). Limited data are available that demonstrate an increase in systemic exposure when the AeroChamber Plus spacer device is used compared with the Volumatic spacer device (see section 4.4).Patients should be instructed in the proper use and care of their inhaler and spacer and their technique checked to ensure optimum delivery of the inhaled drug to the lungs. Patients should continue to use the same make of spacer device as switching between spacer devices can result in changes in the dose delivered to the lungs (see section 4.4). Re-titration to the lowest effective dose should always follow the introduction or change of a spacer device. Special patient groups:There is no need to adjust the dose in elderly patients or in those with renal impairment. There are no data available for use of Seretide in patients with hepatic impairment.Instructions for Use:Patients should be instructed in the proper use of their inhaler (see patient information leaflet)During inhalation, the patient should preferably sit or stand. The inhaler has been designed for use in a vertical position.Testing the inhaler:Before using for the first time patients should remove the mouthpiece cover by gently squeezing the sides of the cover, shake the inhaler well, hold the inhaler between the fingers and thumb with your thumb at the base, below the mouthpiece and release puffs into the air until the counter reads 120 to make sure that it works. The inhaler should be shaken immediately before releasing each puff. If the inhaler has not been used for a week or more remove the mouthpiece cover, the patients should shake the inhaler well and release two puffs into the air. Each time the inhaler is activated the number on the counter will count down by one.Use of the inhaler:1. Patients should remove the mouthpiece cover by gently squeezing the sides of the cover 2. Patients should check inside and outside of the inhaler including the mouthpiece for the presence of loose objects.3. Patients should shake the inhaler well to ensure that any lose objects are removed and that the contents of the inhaler are evenly mixed4. Patients should hold the inhaler upright between fingers and thumb with their thumb on the base, below the mouthpiece.5. Patients should breathe out as far as is comfortable and then place the mouthpiece in their mouth between their teeth and close their lips around it, Patients should be instructed not to bite the mouth piece.6. Just after starting to breathe in through their mouth, patients should press firmly down on the top of the inhaler to release Seretide, while still breathing in steadily and deeply. 7. While holding their breath, patients should take the inhaler from their mouth and take their finger from the top of the inhaler. Patients should continue holding their breath for as long as is comfortable.8. To take a second inhalation, patients should keep the inhaler upright and wait about half a minute before repeating steps 3 to 7.9. Patients should immediately replace the mouthpiece cover in the correct orientation by firmly pushing and snapping the cap into position. The cover does not require excessive force and it will click into positionIMPORTANTPatients should not rush stages 5, 6 and 7. It is important that patients start to breathe in as slowly as possible just before operating their inhaler. Patients should practise in front of a mirror for the first few times. If they see "mist" coming from the top of their inhaler or the sides of their mouth they should start again from stage 2.Patients should consider getting a replacement when the counter shows the number 020. The counter will stop at 000 when all the recommended puffs have been used. Replace the inhaler when the counter reads 000.Patients should never try to alter the numbers on the counter or detach the counter from the metal canister. The counter cannot be reset and is permanently attached to the canister.Cleaning:Your inhaler should be cleaned at least once a week. 1. Remove the mouth piece cover.2. Do not remove the canister from the plastic casing.3. Wipe the inside and outside of the mouthpiece and the plastic casing with a dry cloth or tissue.4. Replace the mouthpiece cover in the correct orientation. The cover does not require excessive force and it will click into position.DO NOT PUT THE METAL CONTAINER IN WATER
Paediatric populationChildren and adolescents <16years taking high doses of fluticasone propionate (typically ≥ 1000 micrograms/day) may be at particular risk of systemic effects. Systemic effects may occur, particularly at high doses prescribed for long periods. Possible systemic effects include Cushing's syndrome, Cushingoid features, adrenal suppression, acute adrenal crisis and growth retardation in children and adolescents and more rarely, a range of psychological or behavioural effects including psychomotor hyperactivity, sleep disorders, anxiety, depression or aggression. It is recommended that the height of children receiving prolonged treatment with inhaled corticosteroid is regularly monitored. The dose of inhaled corticosteroid should be reduced to the lowest dose at which effective control of asthma is maintained.
Fluticasone PropionateUnder normal circumstances, low plasma concentrations of fluticasone propionate are achieved after inhaled dosing, due to extensive first pass metabolism and high systemic clearance mediated by cytochrome P450 3A4 in the gut and liver. Hence, clinically significant drug interactions mediated by fluticasone propionate are unlikely.In an interaction study in healthy subjects with intranasal fluticasone propionate, ritonavir (a highly potent cytochrome P450 3A4 inhibitor) 100 mg b.i.d. increased the fluticasone propionate plasma concentrations several hundred fold, resulting in markedly reduced serum cortisol concentrations. Information about this interaction is lacking for inhaled fluticasone propionate, but a marked increase in fluticasone propionate plasma levels is expected. Cases of Cushing's syndrome and adrenal suppression have been reported. The combination should be avoided unless the benefit outweighs the increased risk of systemic glucocorticoid side-effects.In a small study in healthy volunteers, the slightly less potent CYP3A inhibitor ketoconazole increased the exposure of fluticasone propionate after a single inhalation by 150%. This resulted in a greater reduction of plasma cortisol as compared with fluticasone propionate alone. Co-treatment with other potent CYP3A inhibitors, such as itraconazole, is also expected to increase the systemic fluticasone propionate exposure and the risk of systemic side-effects. Caution is recommended and long-term treatment with such drugs should if possible be avoided.
Potent CYP3A4 inhibitorsCo-administration of ketoconazole (400 mg orally once daily) and salmeterol (50 micrograms inhaled twice daily) in 15 healthy subjects for 7 days resulted in a significant increase in plasma salmeterol exposure (1.4-fold Cmax and 15-fold AUC). This may lead to an increase in the incidence of other systemic effects of salmeterol treatment (e.g. prolongation of QTc interval and palpitations) compared with salmeterol or ketoconazole treatment alone (see Section 4.4).Clinically significant effects were not seen on blood pressure, heart rate, blood glucose and blood potassium levels. Co-administration with ketoconazole did not increase the elimination half-life of salmeterol or increase salmeterol accumulation with repeat dosing.The concomitant administration of ketoconazole should be avoided, unless the benefits outweigh the potentially increased risk of systemic side effects of salmeterol treatment. There is likely to be a similar risk of interaction with other potent CYP3A4 inhibitors (e.g. itraconazole, telithromycin, ritonavir).
Moderate CYP 3A4 inhibitorsCo-administration of erythromycin (500mg orally three times a day) and salmeterol (50 micrograms inhaled twice daily) in 15 healthy subjects for 6 days resulted in a small but non-statistically significant increase in salmeterol exposure (1.4-fold Cmax and 1.2-fold AUC). Co-administration with erythromycin was not associated with any serious adverse effects.
FertilityThere are no data in humans. However, animal studies showed no effects of salmeterol or fluticasone propionate on fertility.
PregnancyA moderate amount of data on pregnant women (between 300-1000 pregnancy outcomes) indicate no malformative or feto/neonatal toxicity of salmeterol and fluticasone propionate. Animal studies have shown reproductive toxicity after administration of beta-2-adrenoreceptor agonists and glucocorticosteroids (see section 5.3).Administration of Seretide to pregnant women should only be considered if the expected benefit to the mother is greater than any possible risk to the foetus.The lowest effective dose of fluticasone propionate needed to maintain adequate asthma control should be used in the treatment of pregnant women.
LactationIt is unknown whether salmeterol and fluticasone propionate/metabolites are excreted in human milk. Studies have shown that salmeterol and fluticasone propionate, and their metabolites, are excreted into the milk of lactating rats. A risk to breastfed newborns/infants cannot be excluded. A decision must be made whether to discontinue breast-feeding or to discontinue Seretide therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
|System Organ Class
|Adverse Event
|Infections & Infestations
|Candidiasis of the mouth and throat
|Immune System Disorders
|Hypersensitivity reactions with the following manifestations:
|Cutaneous hypersensitivity reactions
|Angioedema (mainly facial and oropharyngeal oedema)
|Respiratory symptoms (dyspnoea)
|Respiratory symptoms (bronchospasm)
|Anaphylactic reactions including anaphylactic shock
|Endocrine Disorders
|Cushing's syndrome, Cushingoid features, Adrenal suppression, Growth retardation in children and adolescents, Decreased bone mineral density
|Metabolism & Nutrition Disorders
|Psychiatric Disorders
|Sleep disorders
|Behavioural changes, including psychomotor hyperactivity and irritability (predominantly in children)
|Depression, aggression (predominantly in children)
|Not Known
|Nervous System Disorders
|Very Common1
|Eye disorder
|Cardiac Disorders
|Cardiac arrhythmias (including supraventricular tachycardia and extrasystoles).
|Atrial fibrillation
|Angina pectoris
|Respiratory, Thoracic & Mediastinal Disorders
|Very Common2,3
|Throat irritation
|Paradoxical bronchospasm
|Skin and subcutaneous tissue disorders
|Musculoskeletal & Connective Tissue Disorders
|Muscle cramps
|Traumatic fractures
Description of selected adverse reactionsThe pharmacological side effects of beta-2-agonist treatment, such as tremor, palpitations and headache, have been reported, but tend to be transient and reduce with regular therapy.Due to the fluticasone propionate component, hoarseness and candidiasis (thrush) of the mouth and throat can occur in some patients. Both hoarseness and incidence of candidiasis may be relieved by gargling with water after using the product. Symptomatic candidiasis can be treated with topical anti-fungal therapy whilst still continuing with the Seretide Evohaler.
Paediatric populationPossible systemic effects include Cushing's syndrome, Cushingoid features, adrenal suppression and growth retardation in children and adolescents (see section 4.4). Children may also experience anxiety, sleep disorders and behavioural changes, including hyperactivity and irritability.
Seretide Asthma clinical trialsA twelve month study (Gaining Optimal Asthma ControL, GOAL), in 3416 adult and adolescent patients with persistent asthma, compared the safety and efficacy of Seretide versus inhaled corticosteroid (Fluticasone Propionate) alone to determine whether the goals of asthma management were achievable. Treatment was stepped up every 12 weeks until **Total control was achieved or the highest dose of study drug was reached. GOAL showed more patients treated with Seretide achieved asthma control than patients treated with ICS alone and this control was attained at a lower corticosteroid dose Well-Controlled asthma was achieved more rapidly with Seretide than with ICS alone. The time on treatment for 50% of subjects to achieve a first individual Well-Controlled week was 16 days for Seretide compared to 37 days for the ICS group. In the subset of steroid naive asthmatics the time to an individual Well Controlled week was 16 days in the Seretide treatment compared to 23 days following treatment with ICS.The overall study results showed:
|Percentage of Patients Attaining *Well Controlled (WC) and **Totally Controlled (TC) Asthma over 12 months
|Pre-Study Treatment
|No ICS (SABA alone)
|Low dose ICS (≤500 microgram BDP or equivalent/day)
|Medium dose ICS (>500-1000 microgram BDP or equivalent/day)
|Pooled results across the 3 treatment levels
The Salmeterol Multi-center Asthma Research Trial (SMART)SMART was a multi-centre, randomised, double-blind, placebo-controlled, parallel group 28-week study in the US which randomised 13,176 patients to salmeterol (50μg twice daily) and 13,179 patients to placebo in addition to the patients' usual asthma therapy. Patients were enrolled if ≥12 years of age, with asthma and if currently using asthma medication (but not a LABA). Baseline ICS use at study entry was recorded, but not required in the study. The primary endpoint in SMART was the combined number of respiratory-related deaths and respiratory-related life-threatening experiences. Key findings from SMART: primary endpoint
|Patient group
|Number of primary endpoint events /number of patients
|Relative Risk (95% confidence intervals)
|All patients
|1.40 (0.91, 2.14)
|Patients using inhaled steroids
|1.21 (0.66, 2.23)
|Patients not using inhaled steroids
|1.60 (0.87, 2.93)
|African-American patients
|4.10 (1.54, 10.90)
|Number of secondary endpoint events /number of patients
|Relative Risk (95% confidence intervals)
|Respiratory -related death
|Patients using inhaled steroids
|2.01 (0.69, 5.86)
|Patients not using inhaled steroids
|2.28 (0.88, 5.94)
|Combined asthma-related death or life-threatening experience
|Patients using inhaled steroids
|1.24 (0.60, 2.58)
|Patients not using inhaled steroids
|2.39 (1.10, 5.22)
|Asthma-related death
|Patients using inhaled steroids
|1.35 (0.30, 6.04)
|Patients not using inhaled steroids
Mechanism of action:Seretide contains salmeterol and fluticasone propionate which have differing modes of action. The respective mechanisms of action of both drugs are discussed below.
Salmeterol:Salmeterol is a selective long-acting (12 hour) beta-2-adrenoceptor agonist with a long side chain which binds to the exo-site of the receptor.Salmeterol produces a longer duration of bronchodilation, lasting for at least 12 hours, than recommended doses of conventional short-acting beta-2-agonists.
Fluticasone propionate:Fluticasone propionate given by inhalation at recommended doses has a glucocorticoid anti-inflammatory action within the lungs, resulting in reduced symptoms and exacerbations of asthma, with less adverse effects than when corticosteroids are administered systemically.
Salmeterol:Salmeterol acts locally in the lung therefore plasma levels are not an indication of therapeutic effects. In addition there are only limited data available on the pharmacokinetics of salmeterol because of the technical difficulty of assaying the drug in plasma due to the low plasma concentrations at therapeutic doses (approximately 200 picogram/ml or less) achieved after inhaled dosing.
Fluticasone propionate:The absolute bioavailability of a single dose of inhaled fluticasone propionate in healthy subjects varies between approximately 5-11% of the nominal dose depending on the inhalation device used. In patients with asthma a lesser degree of systemic exposure to inhaled fluticasone propionate has been observed. Systemic absorption occurs mainly through the lungs and is initially rapid then prolonged. The remainder of the inhaled dose may be swallowed but contributes minimally to systemic exposure due to the low aqueous solubility and pre-systemic metabolism, resulting in oral availability of less than 1%. There is a linear increase in systemic exposure with increasing inhaled dose. The disposition of fluticasone propionate is characterised by high plasma clearance (1150ml/min), a large volume of distribution at steady-state (approximately 300l) and a terminal half-life of approximately 8 hours. Plasma protein binding is 91%. Fluticasone propionate is cleared very rapidly from the systemic circulation. The main pathway is metabolism to an inactive carboxylic acid metabolite, by the cytochrome P450 enzyme CYP3A4. Other unidentified metabolites are also found in the faeces.The renal clearance of fluticasone propionate is negligible. Less than 5% of the dose is excreted in urine, mainly as metabolites. The main part of the dose is excreted as faeces as metabolites and unchanged drug.
Paediatric populationThe effect of 21 days of treatment with Seretide Inhaler 25/50 microgram (2 inhalations twice daily with or without a spacer) or Seretide Diskus 50/100 microgram (1 inhalation twice daily) was evaluated in 31 children aged 4 to 11 years with mild asthma. Systemic exposure to fluticasone propionate was similar for Seretide Inhaler with spacer (107pg hr/mL [95% CI: 45.7, 252.2]) and Seretide Diskus (138pg hr/mL [95% CI: 69.3, 273.2]), but lower for Seretide Inhaler (24pg hr/mL [95% CI: 9.6, 60.2]). Systemic exposure to salmeterol was similar for Seretide Inhaler, Seretide Inhaler with spacer, and Seretide Diskus (126 pg hr/mL [95% CI: 70, 225], 103 pg hr/mL [95% CI: 54, 200], and 110 pg hr/mL [95% CI: 55, 219], respectively).
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M.U.M. Home Page
The Review via e-mail
Vol. 20, #18, June 15, 2005
Copyright 2005, Maharishi University of Management
Raja Dean Dodrill to Give Commencement Address
This year's commencement address will be given by Raja Dean Dodrill, a highly successful entrepreneur who has now devoted his life to creating peace and enlightenment for the world.
Raja Dean completed the enlightenment training conference offered by His Holiness Maharishi Mahesh Yogi, founder of Maharishi University of Management, and was appointed to be Raja of the Washington domain. This domain covers Washington, D.C., Maryland, Virginia, West Virginia, North Carolina, and South Carolina.
He plans to establish a university campus in this domain that is affiliated with Maharishi University of Management. He is also establishing Maharishi Peace Palaces in the major cities within his domain.
Currently there are 35 recertified, full-time Governors of the Age of Enlightenment in Raja Dean's domain working to set up Maharishi Peace Palaces and Maharishi Enlightenment Centers that will offer a wide range of services and products, from instruction in the Transcendental Meditation® technique to organic produce and health-related products from MAPI, Inc.
Raja Dean brings world-class business experience to these activities. As an entrepreneur he has headed many successful ventures, most recently Amteva, a software company whose networking middleware enables a user to unify voicemail, e-mail and fax traffic into a single mailbox accessible over an Internet-based network independent of location, time, or device.
Amteva was sold in 1999 to Cisco Systems, Inc., a worldwide leader in networking for the Internet.
Raja Dean lives in the Bethesda, Maryland, Maharishi Peace Palace with his family. He is a long-term practitioner of the Transcendental Meditation technique and has been practicing the TM-Sidhi® program for nearly 30 years.
University, Maharishi School Students Win Awards at World Creativity Competition
Not only did Maharishi School students win more first- and second-place awards than any other school in the world Destination ImagiNation competition, they also won more awards than the entire state of California — and every other state, with the exception of Texas.
Their total of five first- and second-place awards compares to a total of four top awards won by the 27 schools entered from California. Schools from Texas won a total of eight, and Wisconsin had three. All other states and countries had fewer.
There were some 860 teams competing from nearly as many schools — all of them at the global competition by virtue of having been state or country champs. There were 40–60 teams in each category of competition.
Also, two Maharishi University of Management students won two first-place awards in DI Xtreme, a college-level improv competition among a smaller field of six teams. The teams are given a challenge in the morning, have a number of hours to prepare, and then present their solution in the afternoon. Participating were Destination ImagiNation veterans Aaron Hirshberg and Milo Winningham.
"This level of success is just unprecedented," said coach Mark Headlee. "No other school that I know of has ever done anything like this."
He believes their success is the direct result of Consciousness-Based(SM) education. "The Transcendental Meditation technique is the only variable by which you can explain this phenomenon."
Destination ImagiNation is an international creative-problem-solving program that develops cooperative teamwork and critical thinking, as well as building technical and performance skills. The participants come up with ingenious and often wildly entertaining solutions to complex challenges. There are five separate problem challenges for each of three levels of education: elementary, middle, and secondary.
In the category titled Live! It's RaDIo DI!, which involved producing and presenting an eight-minute radio show that's judged on areas such as sound effects, the Middle School team won first place and the Upper School team took second. The Upper School team also received the Renaissance Award, which is not related to a team's score on the various criteria but is a subjective award given by the judges to the team that demonstrates unusual creativity.
In describing the team's unusual creativity, the judges said, "This team took the challenge of designing a technical 'modement' to make sound above and beyond. A motorized corkscrew rotated three dowels, each connected to separate disks that used a piston-style configuration to convert angular momentum into linear movement. This motion was used to rotate three dimmers up and down. This created a warbling sound from a radio. Now, if you can understand any of that, you can understand why this team should win this award. And we won't even tell you about the suspension cage!"
An all-girl Upper School team also won a first-place award in the category Sudden SerenDIpity, which is a short skit developed around the invention of a device and overcoming a problem related to that device.
And in what must be one of the more technically challenging categories — DIsigning Bridges — in which students were required build a bridge of balsa wood that must support nearly 500 pounds, the Middle and Upper School teams both received second-place awards. Winning bridges are scored on length of span, weight of bridge, and weight supported.
The students spend months working on their chosen challenge and then advance through regional and state competitions. A total of seven Maharishi School teams won the top award at state and advanced to the global competition in late May in Knoxville, Tennessee.
One of the winners was Maharishi School senior Michael Cook, who was on the RaDIo DI and DIsigning Bridges teams, as well as performing with the winning college team by virtue of his acceptance as a student this fall at Maharishi University of Management.
"It's fun to work with others," Mr. Cook said. "Solving a problem and then showing everyone the solution is very fulfilling."
Summer Projects Include Removal of Stadium Seats
An outside dining area, removal of the remaining stadium seats, and other construction projects are planned for this summer.
According to project manager David Todt, removal of the hill and old stadium seats east of the playing field will provide a more attractive environment and allow the Maharishi Patanjali Golden Dome and new men's residence halls to be more in accord with principles of Maharishi Sthåpatya Veda(SM) design by giving more exposure to the morning sun.
The earth removed from the site will be used in a new housing development in Utopia Park.
The playing field has been reworked and seeded, and is expected to be ready for use in the fall of 2006. In the meantime, Bobby Warren Field north of campus is being used for student athletic activities such as soccer.
Also planned is a fenced-in area on the west side of the Student Union patio so students can have access to outside dining without having to go all the way around the north end of the building.
In other construction news, the new locker rooms in the Recreation Center are now finished, with lockers, showers, and attractive linoleum flooring.
Also, two more student houses have been completed and are now occupied.
Future plans include repair of campus roads and sidewalks, and construction of bike paths that will connect the residence halls with the major buildings.
Students Give Recognition to Outstanding Faculty
Last month at the annual Teacher Appreciation Celebration, five faculty members received awards from the students for being outstanding teachers.
The students had earlier voted among themselves to select the recipients. At the celebration, each of the five faculty members chosen for recognition was introduced by one or two students, who spoke movingly about the faculty member's exemplary qualities.
The Computer Professionals students selected Peter Just. Denekew Jembere said of Mr. Just that the "accuracy and certainty he has on the topics he presents gives confidence. He certainly knows what he talks about and presents it in a way you wouldn't forget. He just has a way of getting the best out of you."
Juliette Daley, a teacher of improvisational dance, was recognized for her ability to help students tap into the deep reservoir of creativity within them and to express it in movement. In presenting the award, Isaac Nevas said, "Juliette Daley's class is as close as you can come to taking 'Epiphanies 101.'"
Two students spoke highly of Paul Morehead, who teaches physiology and health, a discipline based on the profound knowledge of health contained in the Veda and Vedic Literature. Hilary Jordan described Mr. Morehead as a "sattvic, evolved, respectful, kind, and knowledgeable professor whose heart expands to include everyone around him and whose insight leads all inquiring minds into the depths of the most sacred knowledge of life."
And student Nathan Jones said, "Being in class with Professor Morehead is such a joy because you know his only desire as a teacher is for all of his students to be living 200 percent of life."
Management professor Jane Schmidt-Wilk was recognized for her excellent qualities as a teacher. Student Katie Greenfield said, "Jane Schmidt-Wilk is organized, efficient, inspiring, and a perfect example of an ideal teacher — always giving more and more knowledge, and always connecting it back to consciousness."
And Professor David Pohlman, Department of Maharishi Vedic Science, was recognized for his personal qualities and abilities as a teacher. Student Sharon Gradischnig shared the comments of one of her classmates: "David Pohlman is a professor who teaches with great sensibility, but also has a firm hand. He answers questions from a calm center, with wisdom and inspiration. Most practically, of course, he is a wonderful and effective transmitter of knowledge."
Graduating B.F.A. Students Exhibit Artwork
Seven students who will be graduating with a Bachelor of Fine Arts degree this month will be exhibiting their work in Unity Gallery in the Library June 17–25. The opening reception is Friday, June 17, 8:00–9:00 p.m.
The artists include:
"I'm really excited about the B.F.A. show this year," said digital media professor Gurdy Leete. "The students' work is extraordinary. Those who go to the show will really enjoy the beautiful diversity."
All of the students have websites exhibiting their work. Find links online at webworks.mum.edu. Their websites present some of the work that will be in the exhibit, as well as other projects that they have done, including freelance work for clients.
Many of the students are already working professionally and the others are looking forward to beginning their careers. Ms. De Souza plans to continue her employment with Human Factors as well as doing freelance video work. The Lisefskis and Mr. Estey will do freelance graphic and web design. Ms. Schook plans to do freelance graphic design, while Ms. Martinez will be doing freelance web design, animation, and video. Mr. Mullenneaux will be showing his ceramics and sculpture, including an upcoming ArtWalk exhibit.
More Weight Equipment for Recreation Center
More top-of-the-line weight-training equipment was recently ordered for the Recreation Center, completing the third phase of a major upgrade to the facility and offering everything necessary for a complete workout of all muscle groups.
The world-class weight machines, which together cost $13,500 and are made by Cybex, simulate a workout done with freestanding weights through a system of variable resistance, says Ken Daley, head of the Department of Exercise and Sport Science. Also purchased were some new benches to be used with freestanding weights.
"We had a mid-range facility before, but now we're moving to a new level," Mr. Daley said. "We now have a top-end weight-training area."
The next phase of the upgrade will include more aerobic equipment.
He said that the weight-training facility helps support the required student exercise program. "This equipment helps make our innovative Mod Log program more accessible and easy to do."
Old Cell Phones, Printer Cartridges Earn Equipment for Recreation Center
Don't throw away those old printer cartridges and cell phones. The Recreation Department can recycle them through the FundingFactory, and thereby earn points that can be exchanged for new recreation equipment in order to help out Maharishi University of Management.
"People simply need to donate something they would normally just throw away — cell phones and empty laser and inkjet printer cartridges," says Ken Daley, head of the Department of Exercise and Sport Science. These cartridges can be from printers, fax machines, and even desktop copiers.
Not only will the University receive much-needed equipment for free, those who donate are helping to save the environment.
You can donate your empty cartridges and cell phones by placing them in the collection boxes found at the Recreation Center.
If you have many items, call (641) 472-1112 to schedule a pickup.
If you have any questions about this great opportunity, please e-mail Mr. Daley at firstname.lastname@example.com.
Maharishi Gandharva Veda Music Summer Workshops
This summer the Institute of Maharishi Gandharva Veda Music is offering four two-week voice and bamboo flute workshops.
The workshops will be taught by master Gandharvan Binay Krishna Baral. Participants will learn the structure of a raga.
Workshops will meet Monday through Friday for two consecutive weeks, for a total of 10 hours per workshop. Students may sign up for any workshop, or any combination of workshops. Open to all ages.
Beginner/intermediate level will be 9:00–10:00 a.m., Monday–Friday.
Intermediate/advanced level will be 10:00–11:00 a.m., Monday–Friday.
(The instructor will assign intermediate students to the level most suitable for them.)
Location: Building 151 upstairs suite
The workshop dates are:
The cost is $100 for the 10-lesson, two-week workshop. The special price for Maharishi University of Management and Maharishi School personnel and dependents is $50.
For more information and to sign up, please call Mr. Baral at (641) 472-7000, ext. 3003.
School Tennis Teams Compete at State
Maharishi School tennis players had yet another solid year, with both the girls and the boys competing at the state tournament in both the individual and team competitions, with several third-place finishes.
In the state team competition, the girls were again among the final four for the second year in a row, again finishing in third place.
In the individual competition, seniors Melodia and Coral Morales advanced to the state semifinals, losing a tough match to the eventual champion and then winning their final match to secure third place.
Sophomore Avery Gibson, who played in the number one spot for the team this season, qualified for the state singles competition for the second year in a row. In the first round she easily handled an opponent who had beaten her a week earlier in the regional final, but lost her second-round match to the eventual champion. She then played well in consolation rounds and earned fifth place.
Also competing for the girls in the state team competition were Tasha Blitz, Dariana Travis, and Deborah Swartz.
The boys exceeded expectations this year, making amazing progress during the season and not only earning a spot in the final four of the state team competition, but also, for the first time ever, had all six players qualify for the individual competition.
The boys earned third place in the team competition, losing their first match to the eventual champion from Dubuque, a team that also won the championship last year. But they were dominant in their battle for third place, winning 5-0.
In the individual competition, senior Jeremy Jones, who played number one for the team, won three matches and lost two, finishing seventh in the singles competition.
In the doubles, sophomores Cooper Rose and Mehul Kar also won three and lost two, finishing seventh.
Also qualifying for state was sophomore Devon Jarvis, who played in the number two position on the team this year. And qualifying for the doubles were junior Dhruv Kar and freshman Owen Blake, who won a match at state.
School Student Justin Rocca Goes to State Track Meet
School Student Justin Rocca Goes to State Track Meet
Maharishi School student Justin Rocca enjoyed a successful season, qualifying for the state meet.
Mr. Rocca competed in the 400-meter run at state and finished ninth with a time of 51.45 seconds.
Golf Team Finishes Third in District
Golf Team Finishes Third in District
The Maharishi School boys golf team finished third in the district tournament with a 311, just six strokes behind the two state qualifying teams.
Danny Steinberg shot 75, just three strokes behind the champion. Sam Goldstein had a 77, Max Steinberg 78, and Mitra Muehlman 81. Alternates were Nick Juskewycz with an 83, and Will Courtade with an 86.
®Transcendental Meditation, TM-Sidhi, Maharishi Vedic Science, Maharishi Gandharva Veda, Maharishi Jyotish, Maharishi Sthåpatya Veda, Consciousness-Based, Maharishi Peace Palace, Maharishi Enlightenment Center, Maharishi School of the Age of Enlightenment, and Maharishi University of Management are registered or common law trademarks licensed to Maharishi Vedic Education Development Corporation and used under sublicense or with permission.


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Painfully Healthy, Dangerously Delicious Green Apple Spirulina Cookies
The Goods:
•2 cups rolled oats (I use gluten free)
•3 tbsp Spirulina
•1 tbsp Cinnamon
•2.5 bananas
•1 green apple
•3 Tbsp water
The Deed
•Preheat oven to 350*
•Blend dry ingredients together and add to mixing bowl. Blend fruit/wet ingredients separately and add to dry ingredients.
•Dollop onto baking sheet and bake for 45 minutes (at altitude)
#vegan #vegetarian #paleo #celiacs #glutenfree #dairyfree #spirulina @paleomg (at Lindsey's Kitchen)
Ladies Night rockin the mike at Armeda's. Who knew Miss España knows all the words to Ganstas in Paradise
Oh, hey there APRIL
The girls totally killed it tonight
"One of these things is not like the other."
-Lee (at Gather)
Cap Hill ladies, you should go see Lisa at Namaste #Aveda on 9th… She's does magical things (at Namaste An Aveda Concept Salon)
Fancy bumping into these lovely people on my run (at Cherry Creek Trail)
Best way to end the week: Climbing with these crazies (at Earth Treks Climbing Gym)
Afternoon yoga with the rockstar ladies of Galvanize
@kindsnacks paid us a little morning visit
#galvanizeperks #fuelcreativity #entrepreneurs (at Galvanize)