text:
Barefoot Versus Shod Running: Which Is Best?
- Volume 25 - Issue 5 - May 2012
- 30939 reads
- 14 comments
1. Bramble DM, Lieberman DE. Endurance running and the evolution of Homo. Nature. 2004; 432(7015):345-352.
2. Available at http://en.wikipedia.org/wiki/Ancient_Olympic_Games .
3. Available at http://www.britishmuseum.org/explore/highlights/highlight_objects/gr/f/f... .
4. Trinkaus E. Anatomical evidence for the antiquity of human footwear use. J Arch Sci. 2005; 32:1515-1526.
5. Available at World's Oldest Shoes In Oregon -- 10,000-Year-Old Sandals Found In 1938 Among 70 Pairs Unearthed Within Cave". Seattle Times. December 1, 1999. http://community.seattletimes.nwsource.com/archive/?date=19991201&slug=2....
6. Available at http://en.wikipedia.org/wiki/Areni-1_shoe .
7. Available at http://www.emedicinehealth.com/running/article_em.htm .
8. Cavanagh PR. The Running Shoe Book, Anderson World, Inc., Mountain View, CA, 1980.
9. Denton JD. Break on through. Shoe Guy's list of historic shoes. Running Times, January 2006, p. 78.
10. McDougall C. Born to run: A hidden tribe, superathletes, and the greatest race the world has never seen. Random House, New York, 2009.
11. Available at http://en.wikipedia.org/wiki/Abebe_Bikila .
12. Available at http://en.wikipedia.org/wiki/Zola_Budd .
13. Available at http://www.guardian.co.uk/uk/2005/aug/10/southafrica.past1 .
14. Wit B, De Clercq D, Aerts P. Biomechanical analysis of the stance phase during barefoot and shod running. J Biomech. 2000; 33(3):269-278.
15. Divert C, Mornieux G Freychat P, et al. Barefoot-shod running differences: shoe or mass effect. Int J Sports Med. 2008; 29(6):512-518.
16. Squadrone R, Gallozzi C. Biomechanical and physiological comparison of barefoot and two shod conditions in experienced barefoot runners. J Sports Med Phys Fit. 2009; 49(1):6-13.
17. Smith GA, Bressel E, Branscomb J. Impact acceleration of the leg: comparison of shod and barefoot treadmill running. Med Sci Sports Exer. 2010; 42:133-134.
18. Divert C, Mornieux G, Baur H, et al. Mechanical comparison of barefoot and shod running. Int J Sports Med. 2005; 26(7):593-598.
19. Stockton M, Dyson R. A comparison of lower extremity forces, joint angles, and muscle activity during shod and barefoot running. Proc. 16th ISBS, pp. 251-254, 1998.
20. Aguinaldo A, Mahar A. Impact loading in running shoes with cushioning column systems. J Appl Biom. 2003; 19(1):1-8.
21. Bishop M, Fiolkowski P, Conrad B, Brunt D, Horodyski M. Athletic footwear, leg stiffness and running kinematics. J Athl Training. 2006; 41(4):387-392.
22. De Clercq D, Aerts P, Kunnen M. The mechanical characteristics of the human heel pad during foot strike in running: an in vivo cineradiographic study. J Biomech. 1994; 27(10):1213-1222.
23. Kerr BA, Beauchamp L, et al. Footstrike patterns in distance running. In Nigg BM (Ed.), Biomechanical Aspects of Sport Shoes and Playing Surfaces, University Press, Calgary, 1983, pp. 135-142.
24. Hasegawa H, Yamauchi T, Kraemer WJ. Foot strike patterns of runners at the 15-km point during an elite-level half marathon. J Strength Cond Res. 2007; 21(3):888-893.
Nice post, Dr. Kirby.
I'm in agreement with the majority of your statement.
But for me, two questions still remain:
1. What the science or the clinical logic supporting the promotion and the prescription of BBS (Big Bulky Shoes : light trainer and bigger) for a beginner or a child... (majority of the recommendations by health professionals and retailers)
2. I feel, with your article, that your position is more to the side of the shoes than barefoot. But what are the advantages of BBS over more minimalistic running shoes (Ex: Brooks-Adrenalin (The best-selling running shoe in Canada)) versus racing flats (Brooks T7) or 'so-called' minimalist footwear (Pure line of Brooks)?
ThanksReply to this comment »
There you go again, Blaise, calling traditional running training shoes "big, bulky shoes," which immediately shows your bias against shoes which are not "minimalist" shoes. Maybe I should call minimalist shoes, using your non-scientific terminology, "thin, flimsy and non-protective hhoes (TFNS)." I hope you realize, Blaise, that the terms "big" and "bulky" are both relative terms and imply a negative characteristic to these shoes even though millions of runners worldwide have chosen to run in these shoes and do so, daily, both comfortably and without injury.
Before I even attempt to answer your question, please describe to me the running shoe design parameters that consititute a "big, bulky shoe" for a size 9 men's shoe (US).
1. What is the minimum weight of your "big bulky shoe" category?
2. What is the minimum heel midsole thickness of your "big bulky shoe" category?
3. What is the minimum forefoot midsole thickness of your "big bulky shoe" category?
4. What is the minimum heel height differential thickness of your "big bulky shoe" category?
Kevin A. Kirby, DPM
Adjunct Associate Professor
Department of Applied Biomechanics
California School of Podiatric Medicine
For you, here are the answers
1. What is the minimum weight of your "big bulky shoe" category?
Less is better ... more than 9O z is certainly "maximalist."
2. What is the minimum heel midsole thickness of your "big bulky shoe" category?
Less is better ... more than 20 mm is certainly "maximalist."
3. What is the minimum forefoot midsole thickness of your "big bulky shoe" category?
Less is better ... more than 20 mm is certainly "maximalist."
4. What is the minimum heel height differential thickness of your "big bulky shoe" category?
Less is better ... more than 7 mm is certainly "maximalist."
I define for you the Big Bulky Shoes (or maximalist shoes) like a "light trainer" or bigger.
There is 100 steps between barefoot or Five Fingers and the Hoka or Brooks Beast. The best-selling running shoes in Canada are clearly closer to the Beast than the Five Fingers or the Saucony A5. 95% of the running shoes were (more than two years ago) MAXIMALISTs.
So my two questions are still open.
1. What the science or the clinical logic supporting the promotion and the prescription of "modern" shoes with characteristics like : more than 9O z, stack more than 20 mm and drop more than 7mm) for a beginner or a child (majority of the recommendations by health professionals and retailers)
2. What are the advantages of a "light trainer" or bigger (Ex: Brooks-Adrenalin) over more minimalistic running shoes (ex: racing flats (Brooks T7) or 'so-called' minimalist footwear (Pure line of Brooks) ... or even a Five Fingers?
Please commit yourself with a real answer.Reply to this comment »
I don't know if there is any good science to support the use of what I call a Traditional Traning Flat (TTF) running shoe (what you like to call "big bulky shoes") other than this has, over the last 40 years that I have been running and following the running shoe industry, by trial and error, been found to be a comfortable type of training shoe for running on asphalt and cement throughout the years.
Certainly, the concept of thinner soled running shoes with less heel height differential was not invented by the barefoot advocates and "minimalist shoe" advocates who erroneously think that running in TTFs cause injury and are somehow harmful to runners. We previously called these shoes "racing flats" and, during my years of competing in cross-country and track during junior high school, high school and at the University of California Davis for the Aggies (during the 1970s), we routinely trained and raced in racing flats and TTFs.
There has always been some variation of running shoe construction from manufacturer to manufacturer and even within one shoe manufacturer's line of racing flats and TTFs. This gave us, for many years before this barefoot vs. shod running debate began a few years ago, a fairly wide range of shoes to choose from to train or race in on hard flat surfaces, on rough trails, on grass, or in race situations. However, I do believe that the introduction of newer "minimalist shoes" does add more styles of shoes to the racing flat category and this may benefit those runners that prefer less shoe sole thickness, less shoe cushioning or less heel height differential from their running shoes.
As for what other podiatrists and shoe store salespeople recommend, I really don't know what they recommend, or for that matter, why they recommend the shoes they do. There seems to be a lot of poor shoe choices made by runners, but, luckily, here in Sacramento, we have excellent running shoe stores that do a great job at fitting runners with more appropriate running shoes.
I will use multiple criteria to choose the appropriate shoe for the runner including:
1. foot morphology
2. foot and lower extremity biomechanics
3. body weight
4. running experience
5. type of surfaces being typically run on
6. whether the shoe is intended for training or racing
7. any specific injuries that the runner is currently suffering from
8. any specific injuries that the runner has suffered from in the past
The advantages of TTFs over racing flats or "minimalist shoes" like the Vibram FiveFingers is that the added midsole cushioning can be quite helpful at reducing the need for runners to use modifications to their running form to absorb the shock of running on the hard surfaces inherent to our modern civilization (i.e. asphalt and cement).
In this regard, an interesting paper by Roger Kram and colleagues at the University of Colorado just demonstrated that experienced barefoot runners, running in a lightweight racing flat, caused them to be more metabolically efficient than while running barefoot (Franz JR, Wierzbinski CM, Kram R: Metabolic cost of running barefoot versus shod: Is lighter better? Med Sci Sp Exerc, Feb. 16, 2012, epub ahead of print). These researchers hypothesized that their research agrees with the "cost of cushioning" hypothesis put forward nearly three decades ago by Frederick et al (Frederick EC, Clarke TE, Larsen JL, Cooper LB. The effect of shoe cushioning on theo xygen demands on running. In: B.M. Nigg and B.A. Kerr, ed. Biomechanical Aspects of Sports Shoes and Playing Surfaces. Calgary: University of Calgary; 1983. p. 107-14) in which they proposed that there is a metabolic cost to having the body cushion itself with muscle power rather than shoe cushioining.
This research certainly seems quite reasonable to me from my own clinical experience and my own 40 years of distance running experience but I believe this deserves more investigation to determine why most runners prefer to run in more cushioned shoes with thicker midsoles rather than the thinner soled shoes that you often recommend in your "The Runner's Clinic" website. http://www.therunningclinic.ca/en/clinic-physios/clinic.php
Kevin A. Kirby, DPM
Adjunct Associate Professor
Department of Applied Biomechanics
California School of Podiatric Medicine
I missed one part of your questions. The clinical logic behind the prescription of Traditional Training Flats (TTFs) is that they have worked very well in the past for many runners that I have sold running shoes to, have run and competed with,and have talked to and treated over the past 40 years. In addition, I have found TTFs to personally be very helpful for my own running over the past four decades of running in these types of shoes.
However, that does not also mean that for the trail runner or lighter weight runner or person who runs on softer surfaces on a regular basis, that a thinner-soled shoe with less heel height differential (which some call "heel drop") would not be a preferred style of shoe in many instances. For each individual, there may actually be different styles of running shoes that will work best for them and they may benefit from alternating between one style of running shoe and another style on a alternate day basis.
I worry, Blaise, that you are assuming that every podiatrist does the same thing in regard to running shoe recommendations and in regards to running injury treatment. This could not be further from the truth since there is a wide range of opinion within the podiatric community as to what the best running shoes are for each runner and what is the best way to treat certain running injuries.
I find that many barefoot and minimalist shoe advocates also assume that podiatrists, in general, only are treating runners so that they can make money "selling" prescription foot orthoses. Again, nothing could be further than the truth for the majority of sports podiatrists here in the United States. As a group, most of us got into the field of sports podiatry so we could help runners and other athletes to be able to train and compete in the sports they love, not to just make prescription foot orthoses for no reason other than to make money. Our treatment plans as sports physicians may involve recommending different shoes, recommending strengthening and stretching exercises, physical therapy modalities, gait retraining, getting over-the-counter foot orthoses, prescribing custom foot orthoses, telling the patient to take foot orthoses out of their running shoes, participating in alternative sports activities and/or foot and ankle surgery.
Please don't generalize by making the suggestion that all podiatrists recommend shoes such as the Brooks Adrenaline for all runners because that simply isn't true. This type of suggestion simply widens the gulf between us because those of us who have been practicing sports podiatry for over a quarter century in this great country of ours know that this is not an accurate representation of reality.
Kevin A. Kirby, DPM
Adjunct Associate Professor
Department of Applied Biomechanics
California School of Podiatric Medicine
I enjoyed reading Dr. Kirby's article. I would like to comment about his article based on my 20 years experience as a track coach at the youth, middle school and high school levels.
Anything that fixes stride flaws is helpful. Most young runners overstride and land on their heels. When not corrected, this continues into adulthood. Well cushioned shoes that have a raised heel encourage this. When meets come, athletes switch to spikes that do not have a heel and have no shock absorption at all. From running with a totally different shoe than they are used to, they get calf pain (shin splints) and foot and ankle problems.
To correct this, I have them do stride drills with precision (stride drills performed incorrectly don't help), and a small amount of barefoot running also encourages them to not land on their heel, shorten their stride and encourages the muscles of the leg to function and aid in shock absorption, and not rely on just the shoe.Reply to this comment »
Thanks for contributing your thoughts. I ran competitively as a distance runner from the age of 12 to 22, running distance events in cross country and track in junior high, high school and all four years as an Aggie for the University of California Davis cross country and track teams. We ran barefoot mile intervals on the baseball field at UC Davis between 1975-1979 during cross country season, so barefoot running is nothing new to me, even though we didn't have the barefoot zealots back then that we do today.
I continued to compete in long-distance running events in podiatry school and into my early 40s, running my PR in the marathon of 2:28 between my freshman and sophomore year of podiatry school. So I am no stranger to long-distance running or long-distance running coaching philosophies.
Even during the early 1970s, my coaches were telling high school runners not to over stride so the idea that runners shouldn't over stride is really nothing new and has been part of long-distance coaching philosophy for at last four decades. However, very few coaches at that time were so oddly fascinated by where runners struck on their feet during running, either on their heels, midfoot or forefoot. The smart coaches could care less what part of the foot the runners struck the ground with, but worried more about putting runners across the finish line in the shortest period of time with the least amount of injuries. The best coaches never attempted to change a naturally talented inherent runner's stride pattern but rather coached them to become stronger and faster, and run the most economically for their given inherent structural and biomechanical makeup.
Considering some of your comments, certainly "landing on their heels" for runners can't be considered a "stride flaw" since every piece of research ever done scientifically very clearly shows that the vast majority of runners are heel strikers. Even the research done on elite runners in Japan has showed that of 283 elite runners analyzed at the 9.3 mile mark of a half-marathon, 74.9% were rearfoot strikers, 23.7% were midfoot strikers and only 1.4% were forefoot strikers (Hasegawa H, Yamauchi T, Kraemer WJ: Foot strike patterns of runners at the 15-km point during an elite-level half marathon. J Strength Cond Res, 21:888-893, 2007.)
Certainly, 74.9% of these elite runners didn't have "stride flaws" simply because they were landing on their heels when running. Meb Keflezighi is one of the fastest ever US men's marathoners and runs very, very fast while heel striking in his marathon. Does Meb also have a "stride flaw"? if he does, then I want some of that "flaw"!
Currently, I am seeing many more running injuries in my clinic being caused by runners who are natural rearfoot strikers being instructed by a coach, a friend or someone on the internet to "(not) heel strike" and "land more on their forefoot". In fact, when I lecture now on running injury treatment to groups of podiatrists, physical therapists and other health professionals nationally and internationally, I make a point that the clinician should ask the question if the injured runner has recently been told to start running "more on their forefoot" or that "running on their heels is a stride flaw" as part of their running injury history taking on their initial visit.
Here is a paper I wrote on the subject of the runner patient history from 30 years ago (Kirby KA, Valmassy RL: The runner-patient history: What to ask and why. JAPA, 73: 39-43, 1983).
Currently, in my practice, at least one-third of the injured runners I see are getting injured by trying to unnaturally run on their forefoot. Coaches who are teaching every runner to avoid heel striking along with the coaches who teach that all runners should be running either barefoot or in minimalist shoes are making my clinic much busier than before. However, I feel sorry for the poor runners getting injured when they have been taught by well-meaning coaches that they should run in a kinematic pattern that is unnatural for them.
Thanks again for taking part in the discussion.
Kevin A. Kirby, DPM
Adjunct Associate Professor
Department of Applied Biomechanics
California School of Podiatric Medicine
Dear Kevin,
Again, I cannot disagree with what you say, except for little things.
"I believe this deserves more investigation to determine why most runners prefer to run in more cushioned shoes with thicker midsoles rather than the thinner soled shoes."
Nothing evidence based for the moment on that. I personally think the opposite. Runners prefer lightweight and more simple running shoes (depending on what habits they had). The reason why 95% of the market was TTF/BBS in the last 20 years (except the last 2 years) is the marketing influence of the running shoe industry, and the recommendations that retailers, health professionals (podiatrist, physio, MD, ...) and coaches were doing ... based on NOTHING evidence-based.
To clarify my questions (I feel I didn't have a clear answer to my questions)
Is there science supporting the prescription of "modern" shoes with characteristics like (more than 9O z, stack more than 20 mm and drop more than 7mm: large majority of the running shoe on the market presently) for a BEGINNER or a CHILD.
1. foot morphology : flat
2. foot and lower extremity biomechanics : nothing special
3. body weight : 200 pounds
4. running experience : beginner (start a running program)
5. type of surfaces being typically run on : road - asphalt
6. whether the shoe is intended for training or racing : training
7. any specific injuries that the runner is currently suffering from : nothing
8. any specific injuries that the runner has suffered from in the past : low back pain
Can you explain why a racing flat or a minimalist shoes cannot be an option for that specific person? Is it finally just a personal choice base on perception OR is there good evidence to orient the patient to a specific type of shoe?
Thanks for your time.
BlaiseReply to this comment »
You asked: "Is there science supporting the prescription of "modern" shoes with characteristics like (more than 9O z, stack more than 20 mm and drop more than 7mm: large majority of the running shoe on the market presently) for a BEGINNER or a CHILD."
Not to my knowledge.
I don't generally recommend traditional training flats (TTFs) for children due to their low body mass and more side to side activities in their play. Children seem to do well in thinner soled shoes such as racing flats for running and in thin soled athletic shoes for their everyday sports activities such as basketball, soccer, etc..
As for your second question why a 200 lb, flat footed, beginner runner that will be running on hard surfaces could not use a racing flat to run in, I would personally recommend a TTF rather than a minimalist shoe for this runner due to the runner's body weight and the runner's presumably pronated feet. There is no good scientific evidence for this choice other than treating 1,000s of runners over the past 27+ years with similar size and foot structure. In other words, my personal experience would lead me to recommend the TTF style of shoe, probably a "motion control" or "stability" shoe, but I have no research evidence to back up my personal recommendation.
Hope this now answers all your questions.
Kevin A. Kirby, DPM
Adjunct Associate Professor
Department of Applied Biomechanics
California School of Podiatric Medicine
I have a simple question about landing and changing stride patterns (landing, frequency and length). Do you see many hip flexor injuries as a result of distance runners landing too far in front of their body (center of mass) (on their heels)?
As a coach for the past 12 years and a national level runner for 30+ years, I agree with the idea that natural stride patterns should be left to the athlete and that strength and range of motion aspects should be trained alongside aerobic capacity, etc. But if the forward strike is causing injuries, should we try to change this through drills, exercises, strength and barefoot running?
DaiReply to this comment »
Thanks for taking the time to comment on this interesting subject.
I have not specifically seen hip flexor injuries from overstriding in either high school, colllege or adult recreational or competitive distance runners, but that could certainly be the cause of some of these injurues.
As you know, since you have coached and run at an elite level yourself, overstriding in runners, and especially beginner runners, can be a common problem. I agree that runners should be taught about running efficiency and about the concept that it is often much more metabolically efficient, causing also less stress on the musculoskeletal system, to run with a greater stride frequency and a decreased stride length.
I worry very little about whether the runner heel strikes, midfoot strikes or forefoot strikes as long as they aren't "reaching" with their feet too far ahead of their center of mass at the instant of foot strike. Of course, running velocity also greatly affects stride length and foot strike pattern, but, as a coach, I simply would recommend trying to teach runners to experiment with different running patterns, trying short strides, long strides and medium strides in drills. In addition, I think that barefoot running drills for runners is an excellent method to teach more of the tactile sensation of how each running stride pattern may "feel" to the runner.
At UC Davis, running for the Aggies in the late 1970s, we did barefoot mile intervals while barefoot and in shoes on a grassy baseball field next to Hickey Gym. My mile intervals were approximately 5:03 while barefoot and, with equivalent effort in shoes was approximately 5:08, or 5 seconds faster per mile while barefoot than in shoes. This barefoot running taught me the important lesson, at a relatively young age, of how having less mass on the feet improved performance. Barefoot running also seemed to help my leg fatique, probably because we were often doing double workouts and running 70-85 miles a week at the time, and any activity that was different was a welcome relief for our chronically tired legs.
Many of the best high school and college coaches in the Sacramento area use barefoot running drills on a grassy field to try and train their runners on proper running form and quicker leg turnover. From my personal experiences, I see no problems with occasional barefoot drills and intervals for both the recreational and competitive runner since it certainly will give the runner added variety to his or her training schedule, keeping things more interesting, and hopefully teaching him or her more about how he or she can improve his or her own running form.
Kevin A. Kirby, DPM
Adjunct Associate Professor
Department of Applied Biomechanics
California School of Podiatric Medicine
Dear Kevin,
I am just curious if you are a heel striker or landing on your forefoot when you had your PR of 2:28 (Marathon)? Did you wear racing flats or running shoes with prominent heel rise?
JaneReply to this comment »
Hi Jane:
My personal record (PR) of 2:28:40 in the marathon came when I ran the Sacramento marathon in September 1980 between my freshman and sophomore years in podiatry school. I was 23 years old at the time and was running about 85 miles per week in the hills of San Francisco, where I lived at the time. I took 2nd place in that race, ran near perfect splits for the 1st and 2nd half marathons, and felt like I ran that race about as well as I could.
I had just run the Boston Marathon in April 1979 in 2:31:33, the year before at age 22, but did not pace myself so well in that race, running the first 10 miles in 55:00 but "hitting the wall" at 24 miles, which ruined my chance of breaking the 2:30 barrier. However, during the Boston marathon, I did pass Joan Benoit just before Wellesley. That was pretty cool.
I always raced marathons and all other races for that matter in racing flats or, for track, in racing spikes. However, I normally trained on the roads in my traditional training flats with my foot orthotics inside my shoes. During races, like most other college distance runners of the time, we all ran in thin-soled racing flats to minimize shoe mass and improve performance. I didn't wear orthotics during racing since I knew the added mass of orthotics would probably slow my race times.
In addition, most of my teammates at UC Davis, including the other distance runners I competed against, trained on the roads in traditional training flats that had a thicker sole and slightly larger heel height differential than did our racing flats. A few of my fellow Aggies that I trained with were much faster than me in the marathon, including Steve Palladino (2:16) and Ed Schlegle (2:17). We all ran in thicker soled shoes to train in and then ran in racing flats to race in. Of course, that was 30+ years ago but I believe the same shoe concepts generally still hold true today for the majority of competitive distance runners.
Hope this answers your questions.Reply to this comment »
To answer the remainder of your question, I am a heel striker up to about a 5:30 mile pace. At a running speed faster than a 5:30 mile pace, I become a midfoot striker and, like most runners, run as a forefoot striker at sprinting speeds.
It is funny you ask because in all the years I raced competitively, running against some of California's best distance runners, no one ever seemed concerned as to whether I was a "heel-striker" or not. Meb Keflezighi, the winner of the 2012 US Olympic Trial marathon at the age of 36, ran 2:09:08 for that race, heel striking all the way. Meb has run four marathons in 2:09 and heel strikes in all of them.
As a competitive distance runner, I could care less whether the people I was running with were heel strikers or not. Today, however, some people view runners who "heel strike" as having some sort of running form defect. Nothing could be further from the truth since even over 89% of elite runners are heel strikers at race pace (Larson P, Higgins E et al: Foot strike patterns of recreational and sub-elite runners in a long-distance road race. J Sports Sciences, 29:1665-1673, 2011.)
Kevin A. Kirby, DPM
Adjunct Associate Professor
Department of Applied Biomechanics
California School of Podiatric Medicine at Samuel Merritt College


text:
MCF-7 Cells
human breast adenocarcinoma cell line
General Information
Source of the MCF-7 cell line:
MCF-7 is a cell line that was first isolated in 1970 from the breast tissue of a 69-year old Caucasian woman. Of the two mastectomies she received, the first revealed the removed tissue to be benign. Five years later, a second operation revealed malignant adenocarcinoma in a pleural effusion from which was taken cells for MCF-7. The woman was treated for breast cancer with radiotheraphy and hormonotherapy.
Copyright picture from altogen.com. Reproduced with permission from Altogen Biosystems.
Uses for the MCF-7:
MCF-7 cells are useful for in vitro breast cancer studies because the cell line has retained several ideal characteristics particular to the mammary epithelium. These include the ability for MCF-7 cells to process estrogen, in the form of estradiol, via estrogen receptors in the cell cytoplasm. This makes the MCF-7 cell line an estrogen receptor (ER) positive control cell line.
Characteristics of MCF-7:
In addition to retaining their estrogen sensitivity, MCF-7 cells are also sensitive to cytokeratin. They are unreceptive to desmin, endothelin, GAP, and vimentin. When grown in vitro, the cell line is capable of forming domes and the epithelial like cells grow in monolayers. Growth can be inhibited using tumor necrosis factor alpha (TNF alpha), and treatment of MCF-7 cancer cells with anti-estrogens can modulate insulin-like growth factor finding protein's, which ultimately have the effect of a reduction in cell growth.
Stability of cell line:
Genetically, the MCF-7 line has not been maintained exactly. Originally, it was described as having a karyotype containing 85 chromosomes, which has since been reduced by 16 chromosomes. Today's cell line has a karyotype containing 69 chromosomes. Furthermore, there are genetic discrepancies between the MCF-7 cell line from the Michigan Cancer Foundation and the ATCC cell line. This indicates that the ATCC cell line is of a different source than the other MCF-7 cell lines.
Lab Techniques, Protocols, and Research Methods
siRNA Delivery - In Vivo Transfection Kits
CRO Pre-clinical Research Services: Xenograft animal models
GLP-compliant Cell Banking services
Generation of Stably Expressing Cell Lines in 28 Days
Stable RNAi Cell Line Generation: Stable Gene Knockdown
In Vivo siRNA Delivery: Tissue-targeted siRNA
Encapsulation of Protein, RNA, mRNA, and DNA Molecules into Liposomes
Berkeley Lab MCF7 Breast Cancer Cell Line

subset: commoncrawl


text:
Map It
Map City Services
Metro Newsroom
LouisvilleKY.gov Links
Thursday October 2, 2008
For Immediate Release:Majority Caucus Louisville Metro CouncilContact: Tony Hyatt 574-4137/ 526-3622In mid October, there is no place more beautiful in Louisville Metro than the Jefferson Memorial Forest. One Metro Councilwoman says it is the perfect time of year to not only enjoy the view but get healthy too.
"When the Mayor's Healthy Hometown Hike returns to the Forest this year, I hope everyone will take advantage of an event that shows the beauty of this scenic place," says Councilwoman Vicki Aubrey Welch (D-13).
The Hike will run from 10:00am to 2:00pm on October 18th in the Horine Section of the forest located at 12304 Holsclaw Hill Road.
It will feature five of the Forest's 13 trails. There will be guided tours and many options for those who wish to come out and walk or hike. The trails range from one fifth of a mile up to five miles.
"Metro Parks has done a great job of getting the forest ready for the hike after the storm damage we had on September 14th," says Welch. "This forest is a very special place for many people and we are looking forward to welcoming those people who have never been here before."
For more information about Mayor's Health Hometown Hike, including walking tips and directions as well as other information go to:
Sponsor:Vicki Aubrey Welch (D) 13


text: content Vitamin B3 Overview Vitamin B3, also called niacin and nicotinic acid, is a water-soluble B vitamin. As with the rest of the B-vitamin family, niacin is involved in many aspects of energy metabolism and nervous system function. It plays a role in over 200 enzyme systems that release energy from carbohydrates and fats, metabolize proteins, make certain hormones, and assist in the formation of red blood cells, and perform many other functions. Niacin is thought to lower cholesterol and triglycerides; prevent and treat diabetes (as niacinamide); improve circulation (as inositol hexaniacinate); and relieve arthritis (as niacinamide). A frank niacin deficiency causes pellagra, a condition that affects the skin and GI tract (diarrhea, nausea, vomiting and swollen tongue) and nervous system, (headache, depression, impaired memory, hallucinations and dementia). Niacinamide (nicotinamide) is the biologically active form of niacin. It is the preferred form of supplementation because it lacks the flushing effects of niacin. However, the flushing action may be necessary for its action of lowering cholesterol. In the mid-1950s, research showed that that high doses of niacin (as nicotinic acid) could lower cholesterol levels by a still-unknown mechanism. The other form of niacin (nicotinamide or niacinamide) does not provide a cholesterol-lowering effect, but it may help prevent the development of childhood diabetes (Type I) in high-risk children. Cholesterol and triglyceride levels, heart attacks and strokes are all significantly reduced with niacin therapy (sometimes used alone and sometimes used along with other drug therapy). Overall, the beneficial use of niacin (nicotinic acid, but not niacinamide) to prevent or treat elevated blood lipids and reduce cardiovascular disease risk is well documented. Nicotinic acid consistently lowers total and LDL ("bad") cholesterol (by about 15-20%) and triglycerides (by 10-25%), while increasing levels of HDL ("good") cholesterol (by 15-25%). Unfortunately, the amount of niacin needed to lower cholesterol levels also tends to result in "niacin intolerance" in 15-40% of people who try it and the unpleasant side effect of "skin-flushing" (similar to hot flashes). Dietary Sources: Rich dietary sources of niacin include many high-protein foods such as meat, chicken, tuna and other fatty fish, peanuts, pork and milk. Dosage: The RDA for niacin is only 13-18 mg. The "cholesterol-lowering" dose of niacin (as nicotinic acid) is typically in the range of 250-2000mg/day. Dosing is usually started at the low-end (250mg/day) with increasing doses of 250mg each week or two until blood lipid levels start to normalize (or side effects develop). Side Effects: In the high doses used for controlling cholesterol levels (anything above 100mg/day), nicotinic acid can cause skin flushing and itching of the skin as well as headaches and hypotension (lightheadedness and low blood pressure). The slow-release versions of niacin supplements for controlling blood lipids have the potential for causing liver damage (even at "lower" doses of 500mg/day) – so blood tests to monitor for liver damage are recommended and slow-release, high-dose niacin supplementation should only be undertaken on the advice and guidance by a physician. (Source: www.supplementwatch.com) The following citations present evidence of ongoing research on niacin for dyslipidemia and migraine and experimental investigation in cancer, lung disease, and skin disease. Earlier research with nicotinamide for the treatment of schizophrenia and mental disorders showed evidence of great therapeutic value. However, there is very little current research using in this important non-toxic modality. There is some research in "nicotinic systems in central nervous systems disease." Research Overview 1. Dyslipidemia, alone or in combination with statin drugs – hundreds of studies are evidenced in the literature. 2. Migraine 3. Skin diseases 4. Oral niacin prevents photocarcinogenesis and photoimmunosuppression in mice. 5. Niacin attenuates acute lung injury induced by lipopolysaccharide in the hamster. 6. Early onset juvenile diabetes mellitus controlled with nicotinic acid therapy. 7. Nicotinamide may extend remission phase in insulin-dependent diabetes. 8. Attenuation of amiodarone-induced lung fibrosis and phospholipidosis in hamsters by taurine and/or niacin treatment. 9. Improved skin flap survival with nicotinic acid and nicotinamide in rats. 10. Effects of nicotinate ethyl ester treatment on gingival blood circulation of experimental gingivitis in monkeys. 11. Nicotinic acid in the treatment of chronic circulatory failure in patients with ischemic heart disease. 12. Nicotinamide is a potent inhibitor of proinflammatory cytokines. 13. Nicotinic treatment for degenerative neuropsychiatric disorders such as Alzheimer's disease and Parkinson's disease. 14. Nicotinamide in the treatment of schizophrenia. Vitamin B3 Citations (372) Page12


text:
Save TOH Update: 2013
Grand Prize Winner
Finish Your Basement
DIY According to Stock Photos
Splitting Logs
'Save This Old House' Update: 2013
See whether that Georgia Greek Revival featured on the back page of This Old House magazine escaped demolition, or if that showstopping California Queen Anne found a new owner
Grand Prize Winners: The Search for America's Remodel 2014
How did one of our fellow readers earn our awe—and a $5,000 prize? Well, first he had to "retire" so he could work on the house full-time. Nice job!
Read This Before You Finish Your Basement
Even if it's currently cold concrete and crammed with boxes of off-season duds, the lowest floor of your home probably has loads of potential
If DIY Were Really Like Stock Ad Photos
Images created by photographers to sell to advertisers and publishers are often nothing like reality—especially when they show people working on their homes and using tools
How to Split Logs for Firewood
This Old House landscape contractor Roger Cook shares tools and techniques for quickly, safely splitting firewood
Before and After
Fresh Start for a Master BathA layout overhaul and classic fixtures deliver a dreamy master bath
Yard Upgrade
How to Repair a Flagstone WalkwayThis Old House landscape contractor Roger Cook shows how to affix loose flagstones
How to Store Your Lawn Mower for the Cold SeasonAn end-of-summer tune-up keeps power lawn equipment in top shape
Shop TOH on Wayfair.comMake your home look like a page out of This Old House magazine with products chosen specially by TOH editors


text:
Nadav Kander - More from the series Yangtze, the Long River
Cui Fei - Manuscript of Nature V (2002)
Be-Fun - Fuji Studio, Shibuya 2010.
1. Misplaced Nature
2. Floating Rebar
3. Spikes
4. Fissure
Cathlyn Newell - Concrete Ghosts: Curfew
Artist's statement:
"Curfew provokes the loss of a larger space to fleeting apparitions of darkness and memory.
Simply, the work is the ghosting of a darkened window, made of the strange and violent spatial lines embedded with candlewicks burnt away and trailing smoke true to the term curfew (rooted in the French term, literally to cover the fire).
Fleeting and vanishing (both physically and in memory), the line work is a dance between the fewest lines that can be trusted, and the imagination projected onto a darkened reality.
Its implications and threat of vanishing is the unknown reality, one that seems familiar, though always unfamiliar. Curfew remains something that is there among us, but anxious, fleeting, and aggressive, though even frightened in and of its own being."
Wanting romance but being terrible at it.
Design by Simon Fletcher. Powered by Tumblr.
© Copyright 2010


text:
Burns and lacerations surrounded by vibrant coloration. Reports of injuries with this description are popping up everywhere. The cause: Homebrewed dyes. With the cost of unidentified dyes reaching all-time highs, some people have reached new levels of desperation to get their clothes and armor colored just right. We spoke with the head dye chemist at "I Could Just Dye", the makers of "Suprise!" brand Unidentified Dyes.
"Dye making is no simple task. If the mix is off, you can end up with some very volitile results, which would explain the rash of injuries as of late. People really should leave this sort of thing to the professionals"
But this epidemic of dangerous experimentation isn't relegated to just the home. Last week I saw a man so broken by his need for a hit of color that he was found rubbing a dead Skritt on his legs, screaming, "RED PANTS! RED PANTS! DADDY WANT RED PANTS!"
If you or anyone you love is troubled with dye addiction, please contact your local law enforcement and inquire about services available to the public.


text:
The cost to end the contract with the company that runs the red light camera program could be at least $54,000 if city leaders decide to cancel the contract by July 1, according to city records.
In light of Pinellas County Clerk of Court Ken Burke asking Clearwater and other cities to stop issuing red light camera violations, officials looked to see what it would take to get out of the contract with Redflex Traffic Systems.
Burke argued there are flaws in the system and that his office is spending a disproportionate amount of time dealing with the fallout from violators. Burke said a significant number of red light violations are issued erroneously to the owner of a vehicle, not the driver.
"These citizens are upset with the poor communication, insufficient information and resulting unfair penalties," Burke wrote in a letter dated Feb. 20 to city leaders in Clearwater, St. Petersburg, Gulfport, Kenneth City, South Pasadena and Oldsmar.
Because of Burke's letter, Pam Akin, city attorney asked:
"What would be the consequences to the city under the contract?"
Canceling the entire contract by July 1 would cost $54,000, according to city records.
City leaders are looking to review the six-month trial program's success. The city could be locked into the contract for another two and a half years or have to pay a fee to get out of it. Success is dependent on a 15 percent decrease in violations and the program is cost neutral.
The cameras were installed in July 2012 and warnings were issued to violators. Red light running violations at intersections with cameras have decreased each month since fines started to be issued. The system has helped police in criminal and crash investigations and is financially self sustaining, so far, according to records.
In addition to Burke's directive, circulating the House in Tallahassee is a bill that would repeal cities right to use red light cameras.
Related coverage:
- Red Light Camera Revenue Tops $570K in Clearwater
- Pinellas Clerk Asks Clearwater to Stop Writing Red Light Camera Tickets
- Cameras Cut Red Light Running in Clearwater
- Red Light Cameras Reducing Crashes in Florida
- Red Light Camera Locations in Clearwater
- Red Light Cameras Coming to Clearwater
- Red Light Cameras Running in Clearwater
- City Approved Red Light Camera Proposal
Sign up for the free Clearwater Patch email newsletter to stay connected to your community.


text:
When I first heard that Rob Liefeld's Glory was going to get a relaunch, I was skeptic, but the comic came out and it was pretty rad. Its unfortunate that its coming to end, but the creators should be proud of their work.
This is probably my entry for Project: Rooftop's Fan-art Friday (if the time hasn't expired)
ETA: didn't realize how dark her skin was after I posted this. YIKES. Fixed!
- thisbeastiegirl reblogged this from branch56
- cardigansandpsychedelics likes this
- raphman likes this
- thechrishaley likes this
- mistermiraclesmagnificentmarvels reblogged this from herestoyoumsholly
- herestoyoumsholly reblogged this from lyinginthestreet
- dorkgeekus reblogged this from branch56
- dorkgeekus likes this
- imperious-perfect reblogged this from branch56
- torukun1 reblogged this from renamok
- torukun1 likes this
- renamok reblogged this from branch56
- renamok likes this
- tsujitoons likes this
- calvinamerica reblogged this from branch56
- todayikilledmybestfriend reblogged this from lyinginthestreet
- mooncalfe likes this
- the-white-hole said: Yeah, Liefeld has a penchant for coming up with ideas that're shit when he writes them, but awesome when they're under someone else.
- onigirigeek likes this
- psuedofolio likes this
- werewolfau reblogged this from thehappysorceress
- thehappysorceress reblogged this from branch56
- equiknocks likes this
- devildart likes this
- kqcomics likes this
- gorgeous-monsters likes this
- thehappysorceress likes this
- branch56 posted this


text:
Edible Craft: Marshmallow Dreidels for Hanukkah
Martha Stewart Kids
Hanukkah starts at sundown on Friday, December 11th, so for those of you celebrating, the planning/cooking may have already begun. We think making these marshmallow dreidels would keep kids occupied even longer than playing with an actual dreidel. That is, until they eat them. Get the instructions below.
The team at Martha Stewart must have a thing for marshmallow dreidels, because these aren't the only ones the magazine has featured. These are from a past issue, but the current holiday issue has some chocolate-covered marshmallow dreidels that look fantastic (but, sadly, aren't yet available online).
Both types follow the same method: Spray some clean kitchen shears with cooking spray and cut a big marshmallow into a square. For the ones above, you attach a skewer and then dip the sticky sides of the marshmallow into colored sprinkles. The tip is a nonpareil chocolate.
• Get the full instructions: Marshmallow Dreidels at MarthaStewart.com
For the chocolate version that's in the current issue, you use a pretzel as the stick, dip the marshmallow in chocolate, and attach a Hershey's Kiss for the tip (if memory serves... the magazine wasn't ours).
Has anyone ever made marshmallow dreidels? Any other variations to share?
Related: Chocolate Hanukkah Doughnuts
(Image: Martha Stewart Kids)
7 Comments
Just FYI you can find kosher marshmallows at whole foods (not very large ones though). You can also get halal marshmallows that are pork free.
A second FYI, most kosher marshmallows aren't vegetarian. Pangea sells vegan ones online at veganstore.com, or you can walk into their store in suburban DC.
... I think I just found a craft I MUST do with my (only) Jewish ex-roomie. She used to always help me decorate for Christmas, because she liked the crafts and sparkle. Our Christmas tree very often had Star of David garlands on it.
Hmm... these would look extra fun with sparkle sugar instead of non-pariels...
Marshmallows have pork in them?
Marshmallows are made with gelatin, which is derived from animal bones, possibly including pigs.
How do you get the nonpareil, or hershey kiss, to stick to the marshmallow
Following up on the other FYIs, Whole Foods carries kosher vegan marshmallows, so everyone's covered. Dandies are definitely kosher and I'm pretty sure Sweet and Sara's are too. It might be difficult to find an appropriate sized "tip" to match, though.


text:
passei 18 anos com essa sensação de algo não resolvido comigo e depois de finalmente "resolver", ainda parece que tem coisa errada.
não é culpa de ninguém, nem minha, mas é tão estranho isso ainda me fazer mal mesmo com tudo do jeito que eu esperava (até melhor)
acho que eu só queria não ter que lidar com isso, ou que minha vida tivesse começado do jeito normal e eu não carregasse todas essas drogas de sensações que essa história já me trouxe
I just remember, in particular, Matt LeBlanc and Jennifer Aniston coming up to me and like [asked me], "How are you doing? Is everything okay? You having a good time? Do you need anything?" And I was like, "Uhh… I'm fine. Thank you." They were unbelievably nice.
"I was at a weird bar in Hollywood and Matt LeBlanc, again, was at the bar and some guy went up to him and was like, "Hey man, how are you doing? This is my girl," and like flirting and talking, "Remember me?" And finally Matt goes, "Yeah, yeah that's great," and he walked away and he turned to me- I didn't know him, he was just sitting at the bar next to me- [and said], "I just totally got that guy laid." (Laughs) Like you're awesome! You went out of your way, and now that guy's gonna get laid."
no matter who you ship
no matter who your favourite character is
no matter what your favourite episode is
most friends fans will unite on one thing:
a strong disliking for emily.
"Joey, you wanna put the book in the freezer?"
do you ever wish you could unread a book or unwatch a movie/tv show just so you could go back and experience it all again as if it were brand new
Jennifer Aniston + Ellen
theme por desesperancoso; alguns detalhes por decepcionar, noheartgirl e im-mutable.


text:
Orgasm Spots - Gaba Premature Rapid Ejaculation - Bigger Penis Natural Ways
How to enlarge your penis? what did you say? Is the most excellent penis male magnification to enlarge penis growth? Penis exercises penis pumps penis male magnification pills or else other penis male magnification plans? These questions come up with been bothering men on behalf of many years.
RESULTS NOW GUARANTEED: Enlarge your penis 1-4 inches using the natural male enlargement system. You can enlarge your penis size and girth easily. Get started TODAY with no waiting. See results in as little as 7 days!
Click here now to learn how to enlarge your penis and see results this week >>
Permanent male penis male magnification is an option to men are taking into consideration supplementary and supplementary. This article command discuss trendy note many communal questions concerning lasting male penis male magnification tips and techniques plus penis male magnification merchandise outlay and how it's workable to perceive a better penis permanently through penis male magnification products.
Is Your Penis mode?
You possibly will be there shocked to hear to the conventional size of a man's penis is essentially a lesser amount of than 6 inches. Films and photos can often assign men the harm impression to the bulk of men are essentially enormously well able but the information is to this is not devoted on all.
Penis Male Eenlargement Options on behalf of Men Who Would Like A better Penis
These days present are numerous methods and choices on behalf of men not good enough to rise their penis size both trendy distance end to end and width. Many of these penis male magnification methods include plastic surgery on behalf of penis male magnification vacuum penis pumps penis extenders and stretching plans penis male magnification work out programs and in addition taking pills.
How To catch The most excellent Penis Male magnification Method on behalf of You
The ideal fine on behalf of everlasting penis male magnification depends entirely on the separate and their separate circumstances. All male penis male magnification method comes on a cost - nearly are relatively mean while others are supplementary of an investment on behalf of the work. Present are in addition complimentary penis male magnification exercises and techniques to men can try if they come up with refusal money to invest trendy penis male magnification programs.
Is Penis Male magnification Safe?
Yes the fact is penis male magnification is safe however this in addition depends a cool deal on the everlasting penis male magnification method to you indicate. Trendy broad penis male magnification exercises are safe provided you organize them rightly and survey the directives. The same applies in addition to penis pumps trendy broad provided you in addition survey sternly the directives and don't overdo it. Of curriculum penis pumps assign a supplementary temporary penis male magnification more accurately than a everlasting method. Present are in addition penis male magnification pills to come up with been proven to be there completely safe having the status of they contain all natural herbal ingredients. However to being believed it depends entirely on what did you say? Penis male magnification outcome you indicate.
Hanging weights and traction and penis stretching plans are in addition options to consider however it is critical to the directives are for eternity sternly followed with no exception and to not stuff yourself these penis male magnification methods.
Plastic surgery on behalf of penis male magnification is one more long-term solution but it does draw closer with a variety of disadvantages the cost not being the lone individual.
Does A curve Of The Penis Cause Problems?
Having a curve does not cause a drawback on behalf of magnification solutions.
Which everlasting penis male magnification outcome ought to You Try primary?
This is entirely an separate subject but I would highly urge to you commence with a magnification outcome to comes with a money back assure to requires having the status of inadequately effort or else input from you having the status of workable and to can be there made known to assign nearly penis male magnification results trendy having the status of inadequately having the status of 2 months.
Check away the website under everyplace you command catch individual of the most excellent and mainly highly rated magnification sites online.
Are you happy with the size of your penis? If you are not then take action today! Once you understand how simple it is to enlarge your penis you will wonder why you waited so long.
See results in as little as 7 days GUARANTEED - Click here to start TODAY >> No waiting - Start enlarging NOW >>
Discuss this Article
A penile injury is a scary experience, but knowing what to do ahead of time can help smooth the recovery process. Some first aid tips for the penis are offered here.
These weird penis rash causes can send men running for the doctor's exam room; fortunately, most of them are treatable if men follow the doctor's orders.
Men who experience chronic problems with dry, itchy penile skin after sex often feel frustrated that they are unable to identify the problem and unable to enjoy sex. The information here may help to clear up the issue.
It's summer, and the party is on – but binge drinking, or even having a few too many at the local bar – can have a serious effect on a man's sexual performance. Here's what guys need to know to about the proverbial brewer's droop.
Stretch marks on the penis are common, but most men would prefer to do without them. Here's how men can prevent them from occurring or minimize their appearance.
Find out more about what a penis vitamin crème can do with this quiz. It's hard to really understand the power that's inside each bottle of a penis health crème, but this quiz may help.
Dry penis skin may be a symptom of eczema. Here's what men can do to soothe flaky, itchy, irritated penile tissue.
Penis numbness can be overcome; here's how one man managed to restore penile sensation
Penis Extenders just like the Male Edge is topping the charts for most men already. They are now given the chance to add the necessary length and girth to their penis and take advantage of the power t...
For the most part men are not happy with the size of their penises and this is even more true when women they know talk of past lovers who had huge penises. Men can become insecure because of this and...
Finding the effective method to enlarge penis is some kind of confusing because there are huge amount of information and disinformation on the Internet. Yes there are many various kinds penis male enl...
If your penis is too small to satisfy women you can make it bigger fast with natural techniques. I went from a pitiful 5.5 inches long and 5 inches around to over 8 inches long and exactly 6 inches ar...
Learn The Secrets 3 Natural Penis Enlargement Tips To Substantially Increase Your Manhood Size And Please Women!
There is good news. If you've always wanted to make your penis bigger there is one method that has proven to work exceptionally well for all men. Forget about over-hyped enlargement gimmicks like pill...
Attention How To Enlarge Your Penis Without Pills And Without Surgery - Maximize Every Inch Of Your Penis Fast
It's never been so easy to increase the size of your penis at home safely and naturally. In the past if you wanted to embark upon a discreet penis male enlargement system you would have forced to use ...
Very few men around the world would ever believe what I'm about to tell them but once I explain how the process of naturally enlarging the penis works most of them would quickly get very excited. Your...
If you rewind to as little as a decade ago then all men were really interested in was how to increase the length of their manhood. The reason for this is because for years the length was associated wi...


text:
The conference is now open for public registration:
Receive updates from Wisdom 2.0
There is a revolution occuring in how we view and relate to work.
This new movement is questioning all our assumptions about what it means to develop and operate a business. Elements like mindfulness, wisdom, and compassion are no longer seen as superfluous or useless, but as integral qualities to include in any for- or non-profit endeavor. People are increasingly seeking work that is meaningful, engaged, and where their deeper life purpose is aligned.
Our sold-out event last year brought together 275 leaders and changemakers at Google's NYC offices. We are pleased to come back this year, with an expanded venue.
Join a select group of business leaders and entrepreneurs for Wisdom 2.0 Business to explore the latest trends in innovation and wisdom in business!
See photos from last year here.
Hosted by Soren Gordhamer, Founder, Wisdom 2.0
(Already received a passcode? You can register here.)
The conference will be held at The Altman Building, a historic landmark in the heart of Chelsea. Established in 1886 as the Carriage House for the B. Altman Department Store, it is now a private event venue boasting two floors, vaulted brick ceilings and the original French doors.
The convenient location and unparalleled flexibility of the open floor plan will allow us to craft a unique and outstanding Wisdom 2.0 Business experience. Find detailed directions including local subway stops here.
The Wisdom 2.0 room block at the ACE Hotel is now sold out. Here are some other area hotels you may consider, all within a half mile of The Altman Building:
(Subject to Change. Session times will be announced when confirmed.)
Registration begins at noon; sessions begin at 1:00pm
Give and Take: Why Helping Others Drives Our Success
Talk by Adam Grant, Professor, Wharton School
Mindfulness New York Style: Opportunities and Challenges of Present Moment Living in Fast-Paced Work Environments
with David Gelles, The New York Times; Jana Freidman, Twitter; Golbie Karamie, BlackRock
Diversity and Mindfulness: Why it Matters
by Kruti Patel Goyal, Vice President Business Development, Etsy
Compassion, a Powerful Business Practice
with Sharon Salzberg, Lisette Cooper, and Gina LaRoche
10% Happier: Mindfulness Applications at Work
Talk by Dan Harris, ABC News Anchor
Creativity and Innovation in Business
Fireside chat with Andy Berndt, Vice President, Creative Lab, Google with Soren Gordhamer, Wisdom 2.0
Communication Lessons from Supporting 1.25 Billion People
Talk by Arturo Bejar, Director of Engineering, Facebook
Evening Reception: 6:30pm - 8:30pm
Relationships at Work: Creating Powerful Teams Based on Vulnerability, Trust and Connection
Interview with Eileen Fisher and Diane Poole by Tami Simon, SoundsTrue
Building a Business from the Inside Out: A Soulful Approach to Entrepreneurship
Fireside chat with Marie Forleo and Soren Gordhamer
Compassion in Business
Talk by Tsewang Namgyal, Vice President,The Bank of Tokyo
The Power of Vision and Purpose: The Business Benefits of Working for a Positive Social Impact
Talk by Jonathan Rose, Founder, Jonathan Rose Companies
Mindfulness in Finance: Lessons from Starting a Meditation Program in Corporate America
by Golbie Karamie, Knowledge Strategist & Business Manager, BlackRock Investment
Mindfulness & Leadership in Business
Fireside chat with Mark Bertolini, CEO, AETNA
For information on our annual Wisdom 2.0 event in the Bay area, visit www.wisdom2summit.com
Email firstname.lastname@example.com any time with your questions, thoughts, and ideas -- we love to hear from you!
For sponsorship opportunities, please email us at email@example.com


text:
Photo Essays
Short Resume
Philip Gerard, my first mentor in the Goucher MFA program, at On the Same Page Literary Festival this morning. Hail to all the Gophers out there!
Daniel Wallace - a OTSP FAN FAVORITE!!!
Wilton Barnhardt - he skewered Charlotte but good!
This, and the photos below, are in Jerusalem on our trip there in March. It was so incredibly good we're going back later this summer and working on an archaeological dig with UNC Charlotte with the same folks from the March trip.
El Salvador!
February 22, 2012
El Salvador
Habitat for Humanity
Here's the crew with whom I dug a septic tank all last week.
Another great trip to El Salvador with my Habitat Charlotte buds. Once again I am amazed at the resilience of the Salvadoran people, their generosity of spirit, and good and open hearts. In short, we here in the U.S. have everything and they, by our standards, have little. It's 20 years since the end of a brutal civil war and memories of their personal losses are still fresh and yet they are a positive and hopeful people. It is a pleasure and gift to work together with them for a few short days, helping to make the world a better place if only for a small handful of folks. Showing up there, it feels to me, does matter. And that is reason enough to go. (Click on the Photo Essay tab above for more pictures.)
February 23, 2012 9:53 PM EST
Thanks for lending a hand to make the world a better place!
As always, your photos are terrific! Thanks for sharing your gifts.
- Neeva
February 23, 2012 10:04 PM EST
Neev, you should come with next year!
- Chris Arvidson
Post a comment
Some Favorite Quick Links
OTSP website
Click here to go to the Festival website.
E-mail the author
Wildacres Retreat
Check out Wildacres' website for more information on their wonderful programs.
Ashe County's Fabulous Literary Festival - On the Same Page
Here's info on the Festival and all it's splendid authors.
See information about the Creative Non Fiction MFA program at Goucher College in Baltimore, Maryland.


text:
Rate/Trend Comparison by State/County
Send to Printer
Close Window
Death Rate/Trend Comparison by Cancer, death years through 2010
Virginia Counties versus United States
All Cancer Sites
All Races, Both Sexes
US Rate
to US Rate
US Rate
Priority 1: rising
and above
Priority 2: rising
and similar
Priority 3: rising
and below
Priority 4: stable
and above
Alleghany Cnty and Clifton Forge Cty
Amelia County
Amherst County
Appomattox County
Bristol City
Buena Vista City
Charles City County
Dinwiddie County
Giles County
Hopewell City
Isle of Wight County
King William County
King and Queen County
Lee County
Louisa County
Northampton County
Pulaski County
Russell County
Smyth County
Warren County
Waynesboro City
Winchester City
Wise County
Priority 6: stable
and similar
Bath County
Bedford City
Bland County
Botetourt County
Buchanan County
Buckingham County
Campbell County
Carroll County
Clarke County
Covington City
Craig County
Cumberland County
Dickenson County
Essex County
Floyd County
Grayson County
Greensville County
Henry County
Lunenburg County
Madison County
Manassas City
Manassas Park City
Nelson County
Nottoway County
Page County
Patrick County
Radford City
Rockingham County
Salem City
Scott County
Southampton County
Staunton City
Surry County
Washington County
Priority 7: stable
and below
Priority 5: falling
and above
Accomack County
Brunswick County
Caroline County
Chesapeake City
Culpeper County
Franklin City
Fredericksburg City
Gloucester County
Halifax County with South Boston City
Hampton City
Lynchburg City
Mecklenburg County
Newport News City
Norfolk City
Petersburg City
Portsmouth City
Richmond City
Roanoke City
Suffolk City
Sussex County
Tazewell County
Priority 8: falling
and similar
Albemarle County
Augusta County
Bedford County
Charlotte County
Charlottesville City
Chesterfield County
Colonial Heights City
Danville City
Emporia City
Fairfax City
Falls Church City
Fauquier County
Fluvanna County
Franklin County
Frederick County
Galax City
Greene County
Hanover County
Harrisonburg City
Henrico County
Highland County
King George County
Lancaster County
Martinsville City
Mathews County
Middlesex County
New Kent County
Northumberland County
Norton City
Orange County
Pittsylvania County
Poquoson City
Powhatan County
Prince Edward County
Prince George County
Prince William County
Rappahannock County
Richmond County
Rockbridge County
Shenandoah County
Spotsylvania County
Stafford County
Virginia Beach City
Westmoreland County
Williamsburg City
Wythe County
York County
Priority 9: falling
and below
Alexandria City
Arlington County
Fairfax County
Goochland County
James City County
Lexington City
Loudoun County
Montgomery County
Roanoke County
Created by statecancerprofiles.cancer.gov on 09/20/2014 6:01 pm.
when 95% confidence interval of average annual percent change is above 0.
when 95% confidence interval of average annual percent change includes 0.
when 95% confidence interval of average annual percent change is below 0.
Rate Comparison
when 95% confident the rate is above and Rate Ratio
> 1.10
when unable to conclude above or below with confidence.
when 95% confident the rate is below and Rate Ratio
< 0.90
Priority indices were created by ordering from rates that are rising and above the comparison rate to rates that are falling and below the comparison rate.
Recent trend in death rates is Average Annual Percent Change (AAPC) based on the APCs calculated by
Joinpoint Regression Program
. Due to data availability issues, the time period used in the calculation of the joinpoint regression model may
for selected counties.
Rate ratio is the county rate divided by the US rate.
Source: Death data provided by the
National Vital Statistics System
public use data file. Death rates calculated by the National Cancer Institute using
. Death rates are age-adjusted to the
2000 US standard population
(19 age groups: <1, 14, 59, , 8084, 85+). The Healthy People 2020 goals are based on rates adjusted using different methods but the differences should be minimal. Population counts for denominators are based on Census populations as modified by NCI. The 1969-2011 US Population Data File is used with mortality data.
Note: When the population size for a denominator is small, the rates may be unstable. A rate is unstable when a small change in the numerator (e.g., only one or two additional cases) has a dramatic effect on the calculated rate.
is used to avoid misinterpretation when rates are unstable.
State Cancer Registries
may provide more current or more local data. Data presented on the State Cancer Profiles Web Site may differ from statistics reported by the State Cancer Registries (
for more information


text:
1Touches for RandleThe Cowboys drafted Joseph Randle for just this occasion — to use in case DeMarco Murray was hurt. He has a similar running style and can catch out of the backfield. But for short-yardage work, the Cowboys will probably turn to Phillip Tanner. Even so, the Cowboys have to think about how much they will feature the running game.2Return yardsDwayne Harris holds the top averages for kickoff returns and punt returns in the NFL. The Eagles are one of the worst teams in the league at kickoff coverage, and they have their problems in punt coverage, too. Like those two returns last week, this sets up nicely for Harris.3Catch zoneThe Cowboys have shown they're not that strong at covering backs and tight ends. Problem here is the Eagles have a good pass-catching tight end in Brent Celek, although he hasn't been used much, and of course, LeSean "Shady" McCoy. If the Cowboys linebackers have not solved their drop-depth issues, there will be room to run after the catch.4Boxing McCoySpeaking of Shady, the Cowboys already know the best way to tackle McCoy is not to try it alone. The Cowboys want to get bodies around him, but that will be easier said than done. As important as keeping McCoy and the ball in front of them is, it will also matter how much room the Cowboys allow him to accelerate and cut.5Getting aheadThe Cowboys have taken 7-0 leads in three of the past four games. But they have all been at home. They have not scored first on the road this season. At Philadelphia, the Cowboys can do themselves a favor by getting ahead and staying ahead, potentially limiting how much the Eagles want to turn to their No. 1-rated ground game. — Carlos Mendez
Have more to add? News tip? Tell us


text:
Challenges to the Health Care Law
Last night Senate Democrats defeated an attempt by Republicans to repeal President Obama's health care legislation. The vote went strictly along party lines, though both parties joined forces to repeal an unpopular tax provision on small businesses. In January, House Republicans voted to repeal the act. Earlier this week, a federal judge in Florida ruled the law void, bolstering those trying to overturn it. It's the fourth suit to have been decided. Two ruled part or all of it unconstitutional while the other two upheld it. Twenty more cases are pending. We'll discuss what this means for the future of health care reform.
senior correspondent with Kaiser Health News. She's most recently served as associate editor for CQ HealthBeat, a daily report on health care policy. She has also served as Capitol Hill Bureau Chief for CQ.
health policy correspondent for NPR, author of "Health Care Policy and Politics A-Z," and contributing editor for National Journal Daily.
professor of law at the George Washington University and legal affairs editor of "The New Republic." He's the author of "The Supreme Court," "The Most Democratic Branch," "The Naked Crowd," and "The Unwanted Gaze."
Please familiarize yourself with our Code of Conduct and Terms of Use before posting your comments.


text:
Secret Identity: Self-Portrait in Costume
Artists have been creating self portraits for many years. And drawing ourselves in a fantasy costume is even better. Sandburg Fourth Graders and DCS Middles (a 3rd/4th grade class) drew their self portraits in a costume of their own design.
First we drew a basic face lightly in pencil, paying attention to getting the proportions of the features correct. I talked the students through drawing a life-size oval, adding lines on each side for a neck, then almond-shapes in the center, one eye-width apart. Halfway to chin is nose tip, halfway from nose to chin is center of lips.
Then we circulated around the boxes of hats, sunglasses, scarves, belts, vests and shirts. Everyone looked in the large mirrors and combined the elements until they expressed themselves in a costume.
Then we returned to our basic drawings and began to add our costume shapes to our self portraits. Continuing to look in the mirror, we added hair and eye color, individual features, and then color with crayons and markers.
I brought masks, vests, shirts, even a wig or two, even though I knew it meant washing everything between classes ( I currently teach art lessons to four elementary school classes.) As our time is always limited (One Hour Art) all costume pieces could be worn over the students' regular clothes.
We used large wall mirrors propped up around the room, and small makeup mirrors on the desks.
The mystery and fantasy that appears in these self-portraits is so interesting. Without much time to think about it and with limited costume elements on hand, each student created a totally original alter ego.


text:
Simply confirm your registered email address below and click "Reset Password." We will immediately email you a link back to the site where you can enter a new password for this account.
We've found your existing SPIRIT Family account. Please login below to complete the Facebook login process.
Shop 'til you drop! Visit the Spotted Cow at the Mill Creek Town Center on Saturday Dec. 8th from 1-3pm and meet SPIRIT 105.3 DJ Sarah Taylor who will be giving away an opportunity to win money for a Mill Creek Town Center shopping experience! Also, the FIRST 25 people to mention "Shop 'til you drop!" to the Spotted Cow barista will receive a free drink of choice!
Come join Sarah Taylor and the SPIRIT team, SPIN the prize wheel, and WIN! At the Mill Creek Town Center you can shop, dine, and beautify yourself and more at various retailers, such as Azul, The Nest, Hot Yoga Fitness, Nail Masters and others. See you there!
Copyright © 2014. All rights reserved.


text:
Treveccaís Department of Graduate Psychology hosts professional development day for therapists
This year's featured master therapist was Susan Heitler, PhD, author of From Conflict to Resolution, known for her iconic work in working with conflictual couples. Heitler spoke on 2 clinical topics: Relational conflict resolution and her unique approach to working with depression.
The goal of the event was to provide a day of training for professional counselors.
Read more about Heitler at her website, www.therapyhelp.com


text:
Clinical significanceDetermination of serum triglyceride concentration is used to assess the possible presence of hypertriglyceridemia (increased blood and serum levels of triglycerides). An elevated level of serum triglycerides increases blood viscosity and precipitates platelet aggregation, which in turn results in diminished vascular flow. In addition, increased triglyceride concentrations in the blood coincide with decreased levels of HDL-cholesterol. Patients with ischemic vascular diseases frequently have elevated serum concentration of triglycerides.
1) Physiologic changes in triglyceride concentration
The intake of fatty meal normally entails an increase in the serum concentration of triglycerides. Highest values are measured 6 hours postprandially.
2) Pathologic changes in triglyceride concentration


text:
What Is FUD Crypter?
FUD is acronym for fully undetectable.It is a software that can be used to encrypt your exe files.
What is the use of FUD Crypter?
FUD crypters can be used to encrypt viruses,RAT,keyloggers,spywares etc to make them undetectable from antiviruses.When these exe files are encrypted with Fud crypters they become undetectable with antiviruses
How Does FUD Crypter Work?
The Basic Working Of FUD Crypter is explained below
The Crypter takes the original binary file of you exe and applies many encryption on it and stores on the end of file(EOF).So a new crypted executable file is created.
Original Exe Crypted Exe
001————- 010 101————-110
100|Original File|000-> Cryptor ->010|Original File|110
010————- 111 110————-010
The new exe is not detected by antiviruses because its code is scrambled by the crypter.When executed the new .exe file decrypts the binary file into small the data small pieces at a time and injects them into another already existing process or a new empty one, OR it drops the code into multiple chunks in alternative data streams(not scanned by most a/v) then executes it as a .txt or .mp3 file.
Why Most FUD Crypters Donot Work?
As a FUD crypter becomes popular it also get the eyes of antivirus companies.The antivirus companies update their software and employ detection mechanism that detect the encryption's by the crypter.So, most of the popular FUD crypter are easily detected by antiviruses.
Where can I test Whether my Crypter is FUD or not?
To test you crypter encrypt any virus with it and test it on http://scanner.novirusthanks.org and make sure you check the box Do not distribute the sample .
What is FUD Crypter?
What Is FUD Crypter?


text:
626 S. Miami Ave.
Miami, FL 33130
Category: Bars and Clubs
Region: Central Dade
Elvis Presley perhaps wasn't the world's foremost expert on relationships and marriage. He was an alleged womanizer, after all, and had deep, Freudian mommy issues. (Not to mention he was also rumored to be impotent near the end of his life.) Nevertheless, Elvis marrying couples will likely never wear thin. OK, maybe not the real Elvis, but a spot-on look-alike such as the one presiding over the annual Valentine's Day Wedding Bashat Tobacco Road. In its fourth year, the bash was conceived by resident DJ and head promoter Oski Gonzalez. After hitting a small roulette jackpot in Las Vegas, Gonzalez celebrated by marrying his girlfriend at a kitschy Elvis-themed wedding chapel. He had so much fun he decided to hire an Elvis impersonator to wed the Valentine's Day weekend crowd at Tobacco Road in a non-legally binding midnight ceremony. "We're going to try to re-create what [my wife and I] did in Vegas," Gonzalez told New Timeslast year. "It's really cheesy, but it's really cool." Of course no wedding is complete without music — three stages' worth.
Fri., Feb. 10, 6 p.m., 2012


text:
May 2011 - Money Morning - Only the News You Can Profit From
With a Weak U.S. Housing Market, Is Home Ownership Still a Good Investment?
Owning a home has long been a goal for many Americans, but now more people consider U.S. homeownership a poor investment choice and are kissing that plan goodbye.
Since the housing market collapsed in 2008, forcing millions of underwater homeowners out of their houses, real estate has become a scary and unreliable investment option.
"The emotional scars left by the collapse are changing the American psyche," Pete Flint, chief executive of real estate Website Trulia.com, told The New York Times. "There was a time when owning a home was a symbol you had made it. Now it's OK not to own."
- Metals vs. Stocks: Investors' Best Bet Right Now
Record Low Interest Rates Create Stampede to Issue Corporate Bonds
With interest rates at or near historic lows, companies have been issuing corporate bonds at a breathtaking pace, setting a weekly record this month.
Excluding financial services companies, corporate borrowing for the week ending May 20 reached $29.7 billion, which beat the previous weekly record of $29.04 billion set last September.
Those rushing to add corporate debt this year include some companies already flush with cash, such as Google Inc. (Nasdaq: GOOG), Microsoft Corp. (Nasdaq: MSFT), and Johnson & Johnson (NYSE: JNJ).
With the U.S. Federal Reserve buying up government debt, yields on such benchmarks as the 10-year Treasury note fell from 3.725% in early February to 3.118% in mid-May. Corporate bonds are priced against Treasuries, so when yields fall on government bonds it makes corporate borrowing cheaper.
The unusually low interest rates make acquiring debt very attractive even for companies with no immediate need for the money.
Buy, Sell or Hold: American International Group Inc. (NYSE: AIG) Is Not Worth the Risk
American International Group Inc. (NYSE: AIG) provides insurance services to an international market place. In 2008, the company was bailed out of its positions by the U.S. government, which owned 92% of AIG at its peak.
AIG last week priced new equity, allowing the government to unwind some of its position. The U.S. Treasury sold 200 million shares, or 15% of its AIG stake on Tuesday, but still has 77% ownership of the insurer and another 1.5 billion shares to sell before it is fully out of its investment.
That means this is just the first of many liquidity events. And you don't want to own a stock when you know that a company's largest equity holder is on a mission to get out of its position. Long-term weakness will prevail in this case.
So it's time to "Sell" AIG — until the U.S. government finishes diluting current shareholders by dumping its equity.
- Five Ways To Profit As Coffee Prices Soar
Don't be Fooled: U.S. Banks Aren't as Strong as They Look
U.S. banks are seeing positive trends in several measures of their health.
That's the good news.
Unfortunately, U.S. banks continue to struggle with some much-more-deeply entrenched problems. Those problems pose a major threat to banking-system health.
And they could even cause the U.S. economy to stumble.
Investors who have been heavily and successfully invested in emerging markets, commodities and precious metals have started to repatriate capital back into the U.S. market in anticipation of domestic growth.
However, to really gauge whether that's the correct move to be making right now, those investors would be wise to keep an eye on U.S. banking trends.
The message here is clear: Don't be fooled by the "official" outlook for U.S. banks – the superficial statistics and their in-depth counterparts tell two very different tales.
Good News for U.S. Banks?
It's important to understand that bank-performance statistics are a compilation of the finances of all reporting U.S. banks. Most of this information comes from statistics provided by the U.S. Federal Reserve and the Federal Deposit Insurance Corp. (FDIC). But, as we'll see shortly, the Top 10 U.S. banks hold more than half of the industry's assets, meaning any of the trend numbers are very likely to be skewed – and in a big way.
The good news for banks – particularly the "too-big-to-fail" giants – is that they are experiencing some real improvements … at least, by some important measures.
First-quarter profits totaled $29 billion, a 67% profit over the same quarter last year and the seventh-consecutive quarter of bottom-line improvements, the FDIC said.
Total net charge-offs in the first quarter of 2011 totaled $33 billion, a 37% decline that also included a hefty 39% drop in credit-card charge-offs.
Non-current loans fell 4.7%. And in the area of money that's "reserved" against possible future loan losses, banks set aside a full $31 billion less in this year's first quarter than they did a year ago.
The big banks have already turned in several quarters of profit improvements – based mostly on such declines in loan-loss reserves. And now those institutions are flaunting some highly positive trends in asset quality, which they say will result in lower-loan-loss provisions in the future.
Finally, as a result of such strong capital improvements at the biggest of banks, average capital ratios reached an all-time high.
But, the bigger picture isn't as bright as might be indicated by some of these good trends.
And here we must understand how some of these apparently upbeat numbers and trends can fool us.
To read on, please click here …
How to Turn a Tidal Wave of Profit From the Global Shipping Industry
The shipping industry plays an indispensable role in connecting consumers with their most cherished goods. But many investors unfamiliar with its inner-workings underestimate its potential as a massive profit generator.
Meanwhile, investors who are aware of its importance, and can track the volatile ups and downs of the companies that provide shipping services, frequently score big gains from its oft-repeating profit opportunities.
To get a quick idea of the enormity of worldwide shipping activity, you need only look at the U.S. trade numbers.
Extreme Weather Conditions to Threaten U.S. Agriculture for Next Decade
U.S. agriculture is likely to face harsh weather for the next decade, threatening food production and the livelihood of the nation's farmers.
Extreme weather conditions have slammed the United States this spring. Tornadoes and flooding in many U.S. states have killed hundreds and ripped through millions of acres of farmland. Residents of Joplin, MO continued to sift through rubble this week after being hit Sunday by the nation's deadliest tornado since 1953.
Many U.S. towns now have to rebuild from devastating losses, and many farmers are left with a questionable future for their land.
This prompted a reader to ask the Money Morning Mailbag how U.S. agriculture and food prices have been affected by the nation's drastic weather conditions.
What does all the recent weather catastrophes in the United States mean for crops and farmland? Will this add to food prices that are already too high for our own good?
– Rob S.
Star Hedge Fund Manager Einhorn to Microsoft CEO Ballmer: Time to Go
Citing the stagnant stock performance of Microsoft Corp. (Nasdaq: MSFT) over the past decade, hedge fund manager David Einhorn publicly called for CEO Steven A. Ballmer to step down and "give someone else a chance."
Einhorn made his comments at the annual Ira Sohn Investment Research Conference in New York yesterday (Wednesday). His Greenlight Capital hedge fund owns about 9 million shares of Microsoft stock.
While the tech-heavy Nasdaq Composite Index has gained 34% over the past 10 years, Microsoft has slumped 25%.
Ballmer was named CEO in January 2000.
"His continued presence is the biggest overhang on Microsoft's stock," said Einhorn, who gained notoriety after betting against Lehman Brothers Holdings Inc. (PINK: LEHMQ) four months before its collapse in 2008.


text:
Narrow results:
- East Asia (2)
- Europe (2)
- Southeast Asia (2)
- North America (1)
- Oceania and the Pacific (1)
Time Period
- Social sciences (5)
- History & geography (4)
- Technology (1)
Additional Subjects
- World War, 1939-1945 (4)
- Concentration camps (2)
- Iwo Jima, Battle of, Japan, 1945 (2)
- War posters (2)
- Air warfare (1)
- Autonomy (1)
- Bathing (1)
- Bombers (1)
- Correspondence (1)
- Deportation (1)
- Grumman Avenger (Bombers) (1)
- Letters (1)
- National Memory of the World Register, Latvia (1)
- Naval battles (1)
- Political prisoners (1)
- Recruiting and enlistment (1)
- Siberia (1)
- War bonds and funds (1)
Type of Item
- Prints, Photographs (5)
- Manuscripts (1)
6 results
7th War Loan. Now--All Together
C.C. Beall (1892-1967) was a commercial illustrator who drew comics and book covers. He based the image on this World War II war loan poster on the famous Joe Rosenthal photograph of the second American flag to be raised on Iwo Jima. The photo made a huge impact after being published as part of news reports on the battle. This poster was part of the campaign for a 7th War Loan subscription, which took place in May 1945, just days after victory in Europe. Officials were concerned that the ...
Get Out! The Indies Must be Liberated
This 1945 recruiting poster by the Dutch artist Nico Broekman shows a Japanese soldier being booted from the island of Bali, and the caption, "Get Out! The Indies Must Be Liberated." During World War II, Japan occupied the Dutch East Indies in early 1942. After the surrender, a large number of Dutch submarines and some aircraft escaped to Australia and continued to fight as part of Australian units. In the course of the war, Indonesian nationalists supported by the Japanese took over parts of the country. Allied troops invaded Borneo ...
Bathing Room in the Women's Quarter of the Makassarese Village Near Master Cornelis in Batavia
This 1945 photograph shows women and children bathing at the Kampong Makassar internment camp near Batavia (present-day Jakarta) during World War II. After the Dutch East Indies fell to Japanese forces in 1942, many Dutch residents were forced into internment camps, where they stayed until the end of the war. At Kampong Makassar, which operated from January to August 1945, more than 3,600 women and children were held in a space measuring less than one square kilometer. The photograph is from the collections of the KITLV/Royal Netherlands Institute ...
Military Transport Boats at Iwo Jima
This impressionistic painting of military transport boats approaching Iwo Jima is the work of Harry Reeks (1921-82), an official Marine Corps combat artist who sketched battles in the Pacific during World War II. He arrived at Iwo Jima with the invasion force and spent 30 days there drawing the campaign. The battle for Iwo Jima, from February 19, 1945, to March 26, 1945, was one of the fiercest in the Pacific campaign of the war, and is best remembered for the iconic photograph of Marines raising the flag on the ...
Long a Pacific Mystery, the Secret Naval Base at Truk is Hit by Avengers, February 1944
This illustration shows U.S. Navy planes flying over the island of Truk in the Federated States of Micronesia during World War II. The destruction of the Japanese naval base at Truk was an important element of American strategy in the Pacific theater. It also had a profound effect on the indigenous inhabitants, who were caught up in fighting that lasted from February 1944 to the end of the war. The planes shown are the Avenger torpedo bombers that first saw action in the Battle of Midway in 1942. The ...
Letter on Birch Bark from Siberia by Rasma Kraukle, May 19, 1945
On August 5, 1940, the independent country of Latvia was forcibly incorporated into the Soviet Union, after having been occupied by the Red Army in June of that year. Estonia and Lithuania suffered a similar fate. Thousands of Latvians were arrested for having anti-Soviet views, taking part in resistance movements, being farmers, belonging to political parties, or refusing to join a collective farm. Many were deported to Siberia. People who were in prisons, concentration camps, or settlements in Siberia wrote letters to friends and relatives on birch bark, which was ...


text:
Tag: new york
"Phone-and-drone" journalist Tim Pool, is one of the speakers at the second annual The Future of StoryTelling summit in New York City on Thursday, October 3rd. In the short film below, Pool, now a Producer at VICE Media, shares his experience at the front lines of the Occupy Wall Street movement, live-streaming everything he saw and quickly [...] more »
The best stories across the web on journalism and digital education 1. Did Peru's ambitious laptop program fail? (AP) 2. Cyber bullying measure in New York becomes law (MSNBC) 3. Teaching technology in a no-tech classroom (Orange County Register) 4. How web-based tools can improve teaching (Education Week) 5. Video: Autistic students form iPad band [...] more »
This month, federal agencies and local officials sent two powerful but conflicting messages to the American public about our right to record. On May 14, the Justice Department submitted a letter to the Baltimore Police Department providing in-depth guidance on citizens' right to record. The letter was submitted as part of a court case that dates [...] more »
The MediaShift Innovation Spotlight looks in-depth at one great mash-up, database, mapping project or multimedia story that combines technology and journalism in useful ways. These projects can be at major newspaper or broadcast sites, or independent news sites or blogs. The main spotlights will run every other week, with mini-spotlights running on the off-weeks. What [...] more »


text:
- Winter Weather Update Wrap
- Fantasy Snowfall League
- 400 Died in 1888 NE Blizzard
- Keeps Your Pipes from Freezing
- Sick of Winter? Try THIS.
- Windy and Snowy in Wisconsin
- How We Name Winter Storms
- He Survived. They Think He's Lying.
- The Science Behind Snow Melt
- Snow Chasers Chase Lake Effect Snow
- The Mystery of Lake Effect Snow
- Avoid the Flu at Home
- What is an Alberta Clipper?
- The Phenomenon That Made THESE
- Apocalypse of Ice
- Who Says You Can't Climb a Waterfall?
- Winter Car Survival Kit
- Driving Tips in the Winter
- Save Money This Winter
- Science Behind Snow Melt
- 2000 Miles of Untamed Mother Nature
- Weather Wizard: Freezing Rain
- Playing with Weather
- Is your city the snowiest?
- Making Snow from Scratch
- Foods That Keep You Warm
- Winter Calorie Burners
- The sun's role in a snow storm
- How do you know if the ice is safe?
- Winter driving: What you should have
- Science Behind the Snowflake
- What to do if you're sliding on ice
- How do avalanches trap people?
Winter Storm Wiley spread a swath of snow and ice from the Missouri Valley into the Mid-Atlantic states from Mar. 15-17, 2014.
Below are some of the notables from this late winter storm, by region.
Peak snow total: Haywood, Va. (13.7")
- Washington (Dulles): 11.1"
Washington (Reagan Nat'l): 7.2"
Baltimore, Md. (city): Up to 7.2"
Charleston, W.V. (NWS office): 5"
Philadelphia, Pa.: 4.7" (Brings season total to 67.6", making it the second snowiest winter on record there).
Sleet/ice reports: Under 0.3" ice accumulation in parts of southwest Va., northern N.C.; 0.6" sleet mixed with snow in Roanoke, Va.
HT @PeteSchwartzWx Today is 5th time fed. offices have closed from winter weather in #DC this season. List: #Wiley pic.twitter.com/mhCq79rYOA— The Weather Channel (@weatherchannel) March 17, 2014
Peak snow total: Oak Hill, Ohio (6")
Harrison, Ark: 5"
Sleet/ice reports: 1/2 - 1" sleet in Ellington and near Belleview, Mo.; Generally 0.1" or less ice accumulation in parts of southeast Mo.
Officially 1" of snow today Winter season total of 32.2" which is now ranked at the Top 7 snowiest! #mowx #swmo #SGF pic.twitter.com/hi39gI5lZs— NWS Springfield (@NWSSpringfield) March 16, 2014
MORE ON WEATHER.COM: Winter Storm Wiley Photos
Workers clear snow from the Jefferson Memorial on March 17, 2014 in Washington, DC. (Win McNamee/Getty Images)


text:
Drake & Scull International LLC
Engineering Services United Arab Emirates
| Dubai Financial Market: DSI
Similar to: Melrose Industries Plc, SOGECLAIR SA, Fiskars Oyj Abp
Drake & Scull International LLC engages in the delivery of integrated engineering services. It operates through the following segments: Mechanical, Electrical, and Plumbing (MEP), Infrastructure, Water, and Power (IWP), Civil Works, and Other. The MEP segment carries out mechanical, electrical, plumbing, and sanitation work. The IWP segment deals with infrastructure, water treatment plants, district cooling plants, and power plants. The Civil Works segment handles construction, sanitation work, and real estate activities. The Other segment represents the corporate office, which carries out strategic planning, management of all subsidiaries, treasury management, mergers and acquisitions, corporate branding, and investor relations. The company was founded in 1966 and is headquartered in Dubai, United Arab Emirates.


text:
Gifts and party supplies from your baby's first ultrasound to your baby's first birthday
Our Customers Say...
I will do business with this company again & will recommend them to my family & friends!
- New Mommmy Lisa from Carol Stream
What a wonderful find for new parent gifts, Grandparent gifts, baby gifts and of course shower stuff! A great variety and unique items. The company's name doesn't begin to cover all they have to offer!
- Meredith
A Child's Christmas
A Child's / Grandchild's Christmas Poem
Best Baby Shower, Inc. | 4525 Motorsports Drive | Concord, NC 28027
PHONE: 704-723-9250 | FAX: 704-723-6963 | firstname.lastname@example.com
Copyright 1998-2011 BabiestoBrides.com, Daddy's Tools of the Trade®
Copyright 2000-2011 BestBabyShower.com. All Rights Reserved. All images and text are property of Best Baby Shower, Inc. and may not be duplicated or used without written consent.
Best Baby Shower, Inc. Baby Shower Gifts, Decorations & More The #1 On Line Source For Baby Gifts and Baby Showers, Baby's First Christmas