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Don't miss our top 5 cancer-related stories this month, including a guest commentary from an industry leader, our two-part series on trends in cancer research and more!
By E. Kevin Hrusovsky, PerkinElmer Inc.
As the complexity and volume of data continue to rise, bioinformatics is emerging as one of the cornerstones of personalized medicine, from enabling discovery and development of novel treatments and diagnostics to facilitating collection, analysis and interpretation of data that ultimately helps an individual patient.
By Randall Willis, ddn Features Editor
Aiming beyond the standard of care in oncology
By Randall Willis, ddn Features Editor
Are we really making things better for cancer patients?
By Jim Cirigliano, ddn Contributing Editor
Araxes Pharma and Janssen Biotech ink oncology drug development deal
By Kelsey Kaustinen, ddnFeatures Editor
OSU, Biosortia link up to identify natural products for potential cancer treatments
New Genentech breast cancer drug shows late stage trial success
SOUTH SAN FRANCISCO, Calif.Genentech, a member of the Roche Group, recently announced top-line results of EMILIA, the first randomized Phase III study of trastuzumab emtansine (T-DM1), showing that people who received trastuzumab emtansine lived significantly longer without their disease getting worse (progression-free survival) compared to those who received lapatinib plus Xeloda (capecitabine).
The study enrolled people with HER2-positive metastatic breast cancer who had previously received treatment with Herceptin (trastuzumab) and a taxane chemotherapy. Final results for overall survival (OS), a co-primary efficacy endpoint of EMILIA, are not yet mature. According to Genentech, the safety profile of trastuzumab emtansine was consistent with that seen in previous studies.
Trastuzumab emtansine is an investigational medicine known as an antibody-drug conjugate (ADC). It is comprised of the antibody trastuzumab and the chemotherapy DM1 attached together using a stable linker. It is designed to target and inhibit HER2 signaling and deliver the chemotherapy directly inside HER2-positive cancer cells. According to Genenetch, trastuzumab emtansine "reinforces Roche's personalized healthcare approach of developing targeted medicines to fight cancer."
"Trastuzumab emtansine represents a new approach for the treatment of people with HER2-positive breast cancer that comes from our decades of research on the HER pathway," said Dr. Hal Barron, chief medical officer and head of Global Product Development. "We are excited about the EMILIA results because trastuzumab emtansine is our first antibody-drug conjugate and it may help people who still need more treatment options for this aggressive disease. We will work to submit these data to regulatory authorities as quickly as possible."
Based on these findings, Genentech plans to submit a Biologics License Application for trastuzumab emtansine to the U.S. Food and Drug Administration this year for HER2-positive mBC. In addition, Roche plans to submit a Marketing Authorization Application to the European Medicines Agency this year for the same indication. Genentech licenses technology for trastuzumab emtansine under an agreement with ImmunoGen Inc.
As Luke Timmerman noted at Xconomy.com, "Even though Genentech is responsible for development, and will keep the vast majority of product revenues for itself, today's result is an important moment for ImmunoGen. The company stands to collect a 'mid-single digit' percentage royalty on worldwide sales from T-DM1, because of its contribution to help link the antibody to the toxin. ImmunoGen has no products of its own on the market, and the approval of T-DM1 would provide a significant percentage from a potential multi-billion dollar seller."
EMILIA (TDM4370g/BO21977) is an international, Phase III, randomized, open-label study comparing trastuzumab emtansine alone to lapatinib in combination with Xeloda in 991 people with HER2-positive mBC whose disease progressed after initial treatment with Herceptin and a taxane chemotherapy.
The co-primary efficacy endpoints of the study are progression-free survival (as assessed by an independent review committee) and overall survival. Other study endpoints include safety profile, one-year and two-year survival rates, progression-free survival as assessed by investigator, overall response rate, duration of response and quality of life.
In addition to EMILIA, there are two ongoing Phase III studies of trastuzumab emtansine. MARIANNE is comparing three different regimens (trastuzumab emtansine alone, trastuzumab emtansine plus pertuzumab, and Herceptin plus a taxane chemotherapy) in people with HER2-positive metastatic breast cancer who have not been previously treated for their metastatic disease. TH3RESA is comparing trastuzumab emtansine to physician's choice of treatment in people with HER2-positive metastatic breast cancer who have already received both Herceptin and lapatinib.
According to Genentech, "Building on the results of trastuzumab emtansine studies to date, Roche/Genentech have approximately 30 ADCs in the pipeline."
Code: E03301201

subset: commoncrawl


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Book Description:Award-winning novelist Nicholas Shakespeare has written the definitive biography of one of the most influential literary figures of our time: Bruce Chatwin, whose works' strangely compelling combination of research, first-hand experience, myth, and mystification may have been the real substance of his seemingly contradictory life. Chatwin's first book, In Patagonia, became an international bestseller, revived the art of travel writing, and inspired a generation to set out in search of adventure. Chatwin became a celebrity, while remaining a conundrum. With little formal education, he had become a director of Sotheby's. An avid collector, he eschewed material things and revered the nomadic life. Married for twenty-three years, he had male lovers throughout the world. And only at his death did his personal myth fail him. Nicholas Shakespeare, who was given unrestricted access to his papers, spent eight years retracing Chatwin's steps and interviewing the people who knew him. The result is a biography that is at once sympathetic and revelatory.
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We reached the house. I turned to say something but Seth stopped me by pressing his lips to mine. I was caught off guard but soon i matched his slow rymthm. Butterflies were running through my body and i felt alive. Seth pulled away looking at me like i was the only thing that mattered in his world. "Happy Birthday Janaila." Seth said his voice rough. "I love you." I said my voice sounding breatheless. Seth smiled and picked me up pressing his lips to mine once again. He carried me upstairs not stopping until we reached my room. He laid me down on the bed and finally pulled away. My stomach was turning in excitement , love and adrenilne. Seth looked at me. "Take a shower." He said breaking the silence. I looked at him and i knew there was something else. But he was just as nervous as i was. I shook my head grabbing my towel. I pressed my lips to Seth's one last time before heading to the bathroom. I took a quick shower feeling better. I walked to my room to find it empty. I smiled as i thought about Seth. I walked to my closet picking out a light blue polka dot sweater with some overralls. I put some light blue tights with them since it was getting cool outside. I grabbed my boots. My hair was still straight so i braided it back with meeting the two braids with a blue bow. I brushed did a light gold with some glittery blue eye shadow. I sprayed some Twilight woods purfume on me and i was off. I ran downstairs anxious to see Seth. He was waiting for me at the bottom of the stairs. I jumped into his arms. He held me close like it was the first time he held me in years. It made me feel special . It made me feel like i was meant to be here. He pulled away helping me into his leather jacket. It was big but i didnt want it any other way. "We have to go before were late." Seth said opening the door for me. "Where are we going?" I said with a pleading smile. Seth grabbed my helmet putting it on me. "I can't tell it's a secret." Seth said with a big smile. I pouted which i remembered Seth couldnt see because of my helmet. Seth drove off the main rode's onto the highway. I knew we werent staying in town now. Seth started to slow and i knew i started seeing buildings. Then i seen i saw a sign welcoming us to Seattle. I smiled with excitement. Seth slowed in front of a small motel. He helped me off the bike and took off my helmet. He led me into the small motel. We were greeted by a small dark woman. She smiled. "Were with the Cullen's." Seth said. The woman looked at me and her smile grew. "Your a pretty little thang arent you." She said in a small warm voice. I smiled. "Thank you." I said shyly. "Room 3." She said motioning us towards the stairs. "Thank you." She nodded. She looked at Seth. "You take care of that pretty little thang ya hear boy?" The woman said seriously. Seth smiled and looked down at me. "I can promise you that." Seth said with all love in his voice. It warmed my bones. We walked upstairs. Alice was the door waiting for me. Seth gave me a peck on the lips leaving me with Alice. Alice started on me as soon as i got in the door. Everyone was there. They were all dressed in different types of blues. They all looked stunning. Alice stripped me of my clothes. She handed a baby blue strapless peplum top with long royal blue wide leg trousers. I got dressed and she started on my hair. She did a high ponytail with a swooped bang. She had a blue bow which she put on my ponytail. She just touched up my makeup. When she pulled me into a full length mirror i was blown away. I looked beautiful. My skin looked soft to the touch. My eyes sparkled and looked beautiful. My hair was beautiful it looked shiny and full. Everything was so simple but right. I gave Alice the biggest hug. Renesmee walked up to me with a big smile. She was holding a box. "Happy Birthday Janaila." She said handing me the box. I opened the box slowly awed instantly. The jewlery was beautiful. "Besty Johnson?" I said with a big smile. Renesmee smiled. "Thank you so much." Tears filled my throat i was so overwhelmed. Bella hugged me. "Your welcome sweetie." She said. Rosalie helped me put on my jewlery. We all took pictures. I felt like part of the family. Alice looked at the clock and said we should be leaving.
We all filed into a limo and were off. I didnt know where we going. No one told me. The car started to slow and the car parked. Bella covered my eyes leading me into an unknown place. I felt Seth's warm hands take mine soon they left and i knew he was covering my eyes. Seth uncovered my eyes and all i heard was surprise. I opened my eyes and was in shock. I was surrounded by paintings. Everyone was staring at me with huge smiles or taking pictures or videotaping me. I knew i was a mess . Tears were flowing but i had the biggest smile. I looked at Seth. He was watching me. I walked over to him pressing my lips to his. Seth pulled me as close as could be. I wasnt embarassed that everyone was watching. I loved Seth. This was amazing. I pulled away. "You did all of this ?" I said looking at the paintings surrounding me. "With a little help." Seth said. "No Janaila he planned it all out himself i just made the right calls." Alice said. I looked at Seth. "I love you." I said the tears starting all over. "I love you too Janaila." "Happy Birthday."
I turned back to the party. Thats when i spotted them. I couldn't stop myself i was screaming as i ran to Lila.We gripped each other so hard it i couldnt breathe but i didnt care. Lila was crying i was bubblering. I didnt care i was holding my bestfriend. We pulled away i wiped her tears as she wiped mine. She looked the same but beautiful as ever. I didnt realize how much i missed her until i was holding in my arms. I looked to Evan. He had a smile but his eyes were off. I knew instantly and i felt bad. I walked over to him giving him a big hug. I pulled away and looked at both of them. "I can't believe yall are here." I said my voice shakey with tears and excitement. Lila was bouncing with excitement. "J i've missed you so much." Lila said her voice matching mine. I felt a warm hands wrap around my waist. I looked up and Seth had his big warm smile placed on his lips. "It's nice to finally meet Janaila's bestfriends." Seth said. It warmed me to see everyone come together. I looked at Evan and i could feel the anger and sadness coming off. Before i could say anything Alice spoke. "Guys let's dance." She said pulling me to her. She was wiggling around which made me laugh. Seth pulled me to him and soon we were all dancing. I danced with everybody. It was fun. A slow song came on. Seth stopped and looked past me. Evan was standing looking at me. I looked at Seth asking a silent permission. He understood. He nodded. I walked over to Evan . He took my hand with enough space between us. "You look amazing Janaila." He said his voice low. "Thank you." I said quietly. Evan's eyes watered. "You love him ?" He said his voice breaking. "Very much." I said my voice breaking. Evan looked up not being able to look at me. The song started to die and i knew Evan wasnt staying. Evan looked at me as the song ended. His eyes were watery but i knew he wasnt going to cry. Evan smiled a sad smile. "I loved you Janaila." He said as he kissed me on the top of my forehead. He dropped my hands leaving me. My heart ached not with the lost love but with the loss of a friend. I felt Seth take my hand bringing it to his lips. I laid my head on his chest listening to the song of his heart. Ellie's Gouldings - Figure 8 song came on and Seth pressed my body to his moving to the beat of the song. Elle's voice was magical. My tears stopped and i looked at Seth. He was beautiful. My heart stuttered. It was too much and not enough. I knew the love we had was dangerous to lose. But i knew the love we had was right. I stopped Seth pressing my lips to his. "The moment just called for it." I said with a smile.
Everyone's gifts were beautiful. Seth bent down in front of me. My heart stopped and i looked at him. Everyone became quiet. "Janaila Michaels one day your going to be wife." "This ring is a promise to you that one day you will make me the happiest man alive when you became my wife." "I love you so much and thank you for walking into my life." Seth said as he slid a beautiful blue sapphire ring onto my ring finger. I matched his level pressing my lips to his. Everyone clapped. The party winded down and soon everyone left. The air was cool as we left. Seth led me back to the little motel. He told me he got us a room. The room was small but cozy. Seth started a fire as i changed into my pj's Alice had left for me. They were a blue shorts my fuzzy rainbow slippers and a blue tank top. I walked out and Seth was changed into his pj's. The room was warm and smelled like wood. It reminded me of when me and Lila would have our bonfires at home. I smiled. Seth wrapped his arms around me rubbing his nose agaisnt my neck. I turned so i was facing him. "Thank you for everything." I said. Seth looked at me pressing his lips to mine. We fell back but soon it turned to serious again. Seth looked at me asking me if i was okay. I nodded not being able to speak. He pressed his lips to mine and my 15th birthday night was magical.
I hoped you enjoyed these chapters. There on the happier side. Get ready for the next chappy's there going to be tough. Welp , thanks for reading. Mauh !
Songs i wrote too -
Lana del rey - ride Motorcyle ride to Seattle.
Ellie goulding -
Explosion - Evan goodbye song
Figure it - Seth's and Janaila's Slow Song moment
Sweet Dispostion - Magical night ending
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Video: Tony Bennett & Lady Gaga "The Lady is a Tramp"
The official video for Tony Bennett and Lady Gaga's "The Lady is a Tramp". The song will appear along with several other collaborations on Tony's new album, "Duets 2".
Video: Avril Lavigne "I Wish You Were Here"
Avril's newest single is a ballad called "I Wish You Were Here" featuring a rarely seen softer side of Avril. I have to say I like this side of her way better than her poppy/mean/snarky side. But that's just me. What do you guys think of Avril's new video? Do you buy her tears? -alli
WATCH: Rihanna's New Vid "Cheers (Drink To That)" W/ Three Cameos!
Check out Rihanna's new vid! "Cheers (Drink To That)" with surprise cameos made by Avril Lavigne, Kayne West, and Jay-Z! The vid gives us a little background tour of Rihanna's life at concerts and vacations. Not a bad life I must say! -Krash
MUSIC VIDEO: Lil Wayne's "How to Love"
Lil Wayne has released his latest music video and it is DEEP. There's an awesome storyline throughout the video that hits really serious topics and a "white mighta been" aspect. Watch and let us know what ya think!
Watch: Tinie Tempah ft. Wiz Khalifa "Till I'm Gone"
This song and video are JAMMIN, check it out. -Krash


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A collection of news and information related to Miranda Cosgrove published by this site and its partners.
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Monday's TV Highlights: 'The Goodwin Games' on Fox
'Despicable Me 2' premiere celebrates the return of the minions
Big Time Rush kicks into radio action, readies Summer Break Tour
'ICarly's' Miranda Cosgrove buys in Hollywood Hills
Universal Studios: Despicable Me Minion Mayhem grand opening Monday
Universal Studios: Miranda Cosgrove added to Summer Concert Series
Funny or Die on a mission to live large
Television review: 'Best Player' on Nickelodeon
Revised iPhone app gives attraction wait times for Walt Disney World guests
Two sellouts give Musikfest a strong year of headliner ticket salesStory | Aug 13, 2011 | 4:23 PMAs of today, ticket sales for this year's headline acts at Musikfest (including advance sales for today show by Nick Jonas and Sunday's by Train) have exceeded the total for headline acts at last year's festival. Nick Jonas That'...
Ranking Musikfest's headline shows: None for the ages, but a lot of very goodStory | Aug 16, 2011 | 4:23 PMMy bad news about the headliners at Musikfest's main Steel Stage venue this year: None of them blew me away. Steely Dan at Musikfest: The best this year I didn't have a single concert experience that had that spark to......


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So weird to hear a podcast where I actually think Xander is sober...
Great show guys, I loved every minute of it. Nice to see Killer Reviews branching out from it's film roots into something new. Excellent job!
Want to see some awesome free movies? Check out the Public Domain Movies Thread, in the MOVIES/TELEVISION forum. http://www.killerreviews.com/forums/...-Domain-Movies
Love the show but Malarie needs a nickname. I don't know about you, Butch, but I will definitely be getting Counterstrike when it comes out on 360.
I don't understand the wow thing
I've played alot of mmos, including wow and their all the same
The only one I really got into was star wars galaxies which was so different from everything else until Sony fucking killed it....and there was also fallen earth, which recently went FTP
Even the new star wars mmo is just another cookie cutter game....
Long live Tokyo Sheik - Uncle Frank
I actually think you covered enough for my satisfaction but I can understand though if you felt rush. Butch can be that rabbit from Alice in Wonderland :P
I'm really thinking about getting Witcher 2 today, after hearing about it on the show and watching a ton of videos on youtube. I think I need this. Seems like a game that is well worth the $60 dollar price tag.
Great Show Butch. Pretty cool hearing about the latest games out there.
One quick comment/observation. Any chance of getting Mallory's volume turned up a bit. I found myself turning up the volume to max when she was talking and when you would come in, i had to turn it down. She seemed pretty cool and "fit" into you and xanders personalities (sarchastic, funny, and slightly sexual). Just need her to speak up a little
Great show!
p@rick from southie
Last edited by sirpsychosexy; 05-11-2012 at 07:01 PM.
malory needs to speak up a bit....shes almost at a whipser
and i think an 8bit intro would be way more bad ass
Last edited by toksikshok; 05-11-2012 at 08:25 PM.
Long live Tokyo Sheik - Uncle Frank
Really great first show, you guys. The highest compliment I can pay you is this: I'm not much of a gamer, but I was still entertained by everything you were talking about. Butcher, I thought early on you sounded a little funny, and you confirmed it later when you talked about having a cold. Way to cowboy up and keep recording! I liked Xander's enthusiasm, and I'll be listening closely to his recommendations, since I'm a PS3-only guy, too. And Mallory, what can I say about that voice? I could listen to her read the phone book. You might need to turn her levels up a bit, since sometimes she's a little hard to hear. Looking forward to more from you in the future.


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Daily Mail: Hiding behind the pseudonym Naktis Ireland, the alien enthusiast uploaded the grainy footage, taken on a mobile phone, last month, but claimed to have filmed it in December. The jerky video, which is without audio, appears to show a string of otherworldly glowing fireballs, drifting slowly across the dusk sky.Having spotted the flying objects ion the horizon, the videographer runs frantically into a garden to get a closer look. Steadying his camera he captures one of the alleged UFOs floating in between two semi-detatched houses.Moments later two more appear followed by more, all flying in formation.
But his video was met with a barrage of skepticism online, with one viewer writing on website Out There: 'No audio. This would make some sense, because if a hoaxer hasn't planned out all the "ooh" and "ahh" moments in advance, said hoaxer would then have to produce a credible soundtrack, which may or may not be within the scope of his technical repertoire.'
Another wrote on the same site: 'I'm going to come down hard off the fence and cry "foul".
'This event, if real, would surely have drawn not only media coverage, but also other videos from different locations (how much footage was there of the meteorite?)...read more>>>...
A Personal Journey Into The Mysterious World Of The Occult (Including Magick & Alchemy, The Kabbalah, UFO technology & ET intelligences, The Psychic Senses & Mediumship, Paranormal Phenomena, Meditation & Visualisations, Shamanism, The Unknown & The Unseen ...etc) ...plus all the Conspiracy Theories and Current Affairs.
Tuesday, 23 April 2013
'UFO spotter' posts mysterious video of glowing fireballs floating over Cork
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Found August 26, 2013 on Lakerholicz.com:
PLAYERS: Wesley Johnson, Matt Barnes, Nick Young
TEAMS: Los Angeles Lakers, Los Angeles Clippers
TEAMS: Los Angeles Lakers, Los Angeles Clippers
Wesley Johnson has been a Laker for less than a month, but he's already fitting in with the purple and gold just fine. Laker fans have been clowning on the Clippers for years, and now Johnson is joining in with the festivities. On Sunday night, Johnson took to his Twitter account to ask a simple question regarding "The Fast and the Furious" movie franchise: How many fast and furious will there be?— Wes Johnson (@Weside11) August 26, 2013 So far there's been six movies with a seventh on the way, and according to one Laker fan, it could be a while until they stop shooting altogether: "@ricar_dough562: @Weside11 they gonna stop when the clippers win a championship which is never! Lol" LOL— Wes Johnson (@Weside11) August 26, 2013 Note that Johnson didn't just give a regular "lol" when he retweeted the fan's reply; he went with an all-caps "LOL" – nice work, Wes. Last week, Matt Barnes invaded Nick Young's Instagram account and said the Lakers' run is "over" – I wonder what Barnes would think of this tweet from Wes? The Lakers open their season against the Clippers on October 29. .bottom-of-post-responsive { width: 300px; height: 250px; } @media(min-width: 500px) { .bottom-of-post-responsive { width: 300px; height: 250px; } } @media(min-width: 800px) { .bottom-of-post-responsive { width: 336px; height: 280px; } }
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by Carrie Adams
Lately, Spartan Race has featured some amazing videos on our blog created by fancyboyproductions on YouTube. Fancy Boy has a name – Chris Bennett. Bennett, a teacher and coach in New Jersey, has a vast knowledge of track and road racing and a passion for bringing the stories and the talent to the masses. I recently asked Chris to tell me about his background, the stories behind his videos, and what he hopes they inspire.
Bennett ran in high school for Christian Brothers Academy in NJ, a US Top 10 Cross Country team. From 1994 – 1999 he ran for North Carolina, where he was captain of the Tar Heels cross country and track teams. In 1999 after college, he moved to Palo Alto, CA, where he ran for the Nike Farm Team until 2004. He no longer races but he trains with the high school team he's coaching. "It is very tough to be on that line for years and then step off it and get back on."
He credits his coaching success with learning from his own mistakes and the amazing list of coaches he was lucky enough to have himself, including legends like Tom Heath, the most successful boys coach ever on the East Coast, with no losses since 1973. Bennett was also coahced by Olympian Joan Nesbit-Mabe at Carolina and premier distance coach Jerry Schumacher, who still finds time to answer Bennett's questions to this day. "It was a dream team of coaches," Bennett says. "Everything I say I have stolen from them."
He credits his wife with a lot of his success as well. "The last and most important part of the puzzle is my wife Tammie. We met at Carolina. We were both on the team. She made me. I was lazy. I lacked confidence. She changed that. Any success I have had or will have I owe to her." Together, he and Tammie run the Bennett Running Camps and host cross country and track races. They have open workouts and special events.
Bennett's knowledge of cross country and track history is obvious and his influences vast. He's always thought the sport had the potential to be popular if showcased properly. His videos are organic and focus on the running. "I wanted to show the passion and emotion, the triumph and tribulations. I wanted to show some respect for the overwhelming efforts and stories that athletes have given us," he says. His videos showcase poignant moments in sports history with appropriate background music, which was an easy addition. "I also love music. And I'm cheesy as hell. Put all that together and you have some videos."
Bennett is still surprised how well his videos have done on YouTube–they've gotten one million views, though Bennet has never marketed them. "People write me and tell me they had no idea about Joan Benoit or Seb Coe or the story of Ryan Shay or Heather Dorniden…. our sport needs fans. Baseball players have Babe Ruth and Mickey Mantle. Basketball has Michael Jordan. Track has Alberto Salazar and Henry Rono and Haile Gebrsellasie and Paula Radcliffe. If I can get kids (or adults) to discover these heroes then that's a good thing."
When pressed to pick his favorite video, he can't easily decide. "I love The First Gold. That was my first real memory of watching running. She is such a beast too. What a badass." One of most popular videos is Bennett's latest, and my personal favorite. It's called "The Race" and it highlights the story of Heather Dorniden's heroic rise after a devastating fall during the Big 10 Championships. "That effort is so monumental." Ultimately, it comes down to one question: "Why do you run?"
As a man used to inspiring, he's inspired by seeing others improve, especially when they see it for themselves. As a coach his priority is to instill a love of the sport. He believes that runners can't achieve their potential without loving what they do. When it hurts, the love makes you do what it takes to get through it. He also wants his runners to get rid of the barrier and the limitations.
"I remember the moment I became better after I moved West to run for Nike. I realized that they were all normal guys. There was no magic that I was missing that they mysteriously had. That's not to say that they didn't have magic. They did. But they simply trained their asses off to become magicians. I was willing to do the work. The work itself no longer scared me. I was on my way."
Running, according to Bennet, is "about betterment and challenge. It's about competition with others. It's about competition with yourself. When the book closes on me, if more people hit the trails or stand up and cheer when they see a great effort then I'll be a happy guy."
Bennett keeps busy with his coaching and running camp and he can be followed on Twitter and Facebook. He's website is www.bennettrunning.com. Keep the videos coming FancyBoyProductions. We are eagerly waiting to see what you'll come up with next…
Tags: Bennett Running Camps, carrie adams, Chris Bennett, fancyboyproductions, youtube


text:
Reader Comments (Page 1 of 1)
Damage/Healing definitely is a contributing factor. I often find that on my priest, I get focused down in a large group rather quickly (particularly since I rarely PvP and have little gear for it)... but even though I'm dead/waiting for res while the battle is still raging and the HKs are tallying up for everyone but me, I'll get a really great honor total simply because of the crazy amounts of healing I did while I was tanking the Alliance. :)


text:
You feel shame, you know. And then you get free
Tony Wang
- Location
- San Diego, California, USA
- Birthday
- September 05
- Company
- Bagheera Media
- Bio
- Practicing random acts of factually based thinking.
- Hero Cat Boulette Helps Save
Eleven Humans
February 26, 2014 11:31PM
- Meet Mydia, A Cat Rescued From
the Freeway
February 26, 2014 02:04AM
- Sick Humans, Diabetic Cats,
and Purring
February 24, 2014 11:04PM
- Glucose Reading Update for
Week of 2/23
February 24, 2014 01:05AM
- Felines Sticking Their Butts
In the Air
February 23, 2014 03:45PM
- "Thanks, Alysa. I hated
that people took away the
message that
you shouldn't
February 27, 2014 06:35PM
- "Anyone who says that
felines are not affectionate
is just
being silly. Like
January 24, 2014 11:27PM
- "Hi, Alysa. No problem. I
hope that you enjoy my
January 03, 2014 02:39PM
- "He's a very sweet cat,
and while he's not at risk of
to leave us, he's
December 13, 2013 02:55PM
- "I think it got through
since they started crying.
they will never
November 15, 2013 03:53PM
A Human Who Is Likely to Add a Feline
There is a very kind human who went to extreme lengths to make sure a tiny little kitten was rescued from a roof. The poor kitten had to endure having no food, and cold temperatures before the human was able to rescue her. He did not live in the building where… Read full post »
Another Happy Cat Rescue Story
I really enjoy sharing happy cat rescue stories with you. Today, I get to share a story that shows how cruel little humans can be. It became a happy story because one woman stepped in and helped.
A woman in Atlanta took her goddaughter to a friend's house that had a… Read full post »
Smitten with Kittens Event a Huge Success
Because I have always been an indoor only cat, and this became even more important when I was diagnosed as a diabetic cat, I've never really been able to enjoy living in one of the most pet friendly cities in America. But I am very glad that I live in a… Read full post »
Two Pretty White Cats Need a Furever Home
Hello, my good furiends. It should come as no surprise to you that I love cat rescue stories. This cat rescue story is still being written, but there is no question that it is off to a good start. Now we have to help write a happy ending.
Say hello to… Read full post »
Le Cafe des Chats Offers Purr Therapy
The human tells me that there are certain cities that you consider very fashionable. Apparently, a city named Paris is one of them. He tells me that you humans will get on those noisy long metal tubes to go there because it has many attractions that you want to see. Now,… Read full post »
Cats, Litter Boxes, and the Zoomies
Yesterday, those of you who see my Facebook page will remember that I told you about how I went to use the litter box, and then cleaned my paws on the mat. But as soon as those icky things were off my paws, I decided to run around the house like… Read full post »
Jacey's Filling in For Bagheera Today
Hi, everyone. It's Jacey. Today Bagheera is enjoying a big sun puddle and he does not want to blog. That means I will do the work while he enjoys the sun. The human is always bragging about how I am a sweet and fun cat. Well, what better way to show… Read full post »
Cat Reunites with Family After Five Years
I remember how stressful it was for me, Jacey, and the human when we moved less than a mile away from our old place into our current home. Fortunately, especially for a diabetic cat like me, the human was very careful and made sure that neither Jacey nor I could get… Read full post »
Lucky Continues Helping Special Needs Cats
One of the things that makes me the happiest about the work I do here is helping my fellow special needs cats. I do not care if they are diabetic cats like me, or if there is something else that makes them a special needs cat. My ginger furiend Lucky feels… Read full post »
Diabetic Cats Becoming A Family Tradition
"Human, did I hear that right?"
"What did you hear, Bagheera?"
"I heard you talking to your father. I thought I heard you saying that there is another diabetic cat in the family. Did you say that one of his cats is a diabetic cat like me?"
"Yes, I did, Ba… Read full post »
Hill's Science Can Be Gourmet Feline Food
My human tells me that he enjoys high quality, gourmet food. Did you know that we felines like gourmet food as well? One company that produces a high quality gourmet food is Hill's Science Diet. Now, I need a special diet, since I am a diabetic cat. But just like many… Read full post »
Ten Fascinating Facts About Felines
If I were not a diabetic cat, you probably would never have heard of me. I only started talking to humans other than the one who lives with me because I wanted other humans to know that diabetic cats like me are just as fun, loving, and playful as any cat. … Read full post »
Someone's Getting Comfortable In My Home
"Human, we are doing much better with Marley."
"Yes, we are, Bagheera. Yesterday she came out of the cage and wandered around. She even got up on the ledge. And you were very good. You did not harass her, and you let her wander around on her own. She felt safe."… Read full post »
Let's Work Together to Help Big Cats
For a feline, even though I am diabetic, I am a big cat. I weigh 19 pounds or 8.5 kilos. But I have many cousins that are much bigger than me and who make me look tiny. Siberian tigers, who are the largest members of the feline family, can weigh up… Read full post »
Cats, Sleeping, and Dreaming
We felines get a lot of sleep. Sometimes, after I eat my noms and get the insulin shots I need as a diabetic cat, I love to go to sleep. But many humans wonder, what happens when we felines sleep? Do we have dreams like you humans?
The answer is we… Read full post »
Be Careful With Black Cats on Halloween
While fur color doesn't matter to us felines, to some humans, it means a lot. My fellow felines with black fur have to deal with a lot. Black cats are the last cats to be adopted in a shelter, and there are foolish superstitions that they are bad luck. It is… Read full post »
Look Out for Cats Before Starting Your Car
There are many things that are not fun about being a diabetic cat, but there is one thing that I am grateful for. My human has always kept me inside, and does not let me outside to roam. That means I do not have to worry about getting exposed to the… Read full post »
There Definitely is Feline Affection
"Human, I have a question."
"What is it, Bagheera?"
"Did you miss us when you were away?"
"Of course I did. But you are used to me going away for a little while. I did it many times when you were a tiny little mitten kitten, and it's been part of… Read full post »
What Do We Felines See Out the Window?
One of the things both Jacey and I like to do is look outside the window and see what goes by. The human has put up some fabric things that you call sheer curtains, but we can see out of them. These are good at keeping people from seeing our antics… Read full post »
Adopt a Shelter Dog Month Coming to Close
Now you know I write a lot about diabetic cats or other special needs cats, and I love to share their stories with you. Well, today, I want to remind that that there are other four legged animals in shelters who need furever homes. I of course am happiest when a… Read full post »
Hill's Science Diet Helps Disaster Relief
I told you humans about the horrible floods in Colorado and how one feline saved a lot of human lives. Today I am happy to share some good news from my furiends at Hill's Science Diet. They have announced a unique program to help get food to animal rescue organizations that… Read full post »
What Happens When Felines Eat Too Fast?
"Human, come here!"
"What is it, Bagheera? Are you okay?"
"Yes, I am fine, human, but look at what Marley did! She ate the wet noms so quickly that she vomited. You need to clean that up right now. I do not want that smell around here."
"Calm down, Ba… Read full post »
Diabetic Cats and Low Blood Sugar
I got a question from a human about what happens if a diabetic cat like me gets too much insulin and our blood sugar levels get too low. She is wondering if it is like what happens with a human diabetic, where they will drink a sugary drink to boost their… Read full post »
Time to Share Some Happy Feline Stories
Because diabetic cats like me are special needs cats, I love to share happy news about other special needs felines. And I have some good stories to share with you today.
I told you the story about Darky, a cat who has not one, but two challenges that make the ear… Read full post »
Reaction to Facebook Outage Shows Its Reach
By now, unless you've been hiding under a rock that doesn't have 3G service or access to WiFi, you know that Facebook had some issues yesterday. Now, to some, that was no big deal. You couldn't post yet another picture of your cat, another video of your kids, or tell everyone… Read full post »
Tony Wang's Favorites
On the news of your failing health
Group publishes target list of "anti-Israel" U.S. professors
Familiar: An abuse survivor's take on Ray Rice news
Shameless Self-Promotion
OS Cover Mad Libs - aka verbal Stockholm Syndrome
Are We Sane?
Stepmom Chronicles: In the Norwegian Woods with Sophia
My Savory Veggie Pot Pie


text:
Statement on Drought for the 4 and 7-month
periods ending 30th April 2006
ISSUED 5th May 2006 by the National Climate Centre
A dry start to the year has seen short-term rainfall
deficiencies emerge across parts of eastern Australia, especially
over inland eastern Queensland and parts of New South Wales, the Bureau of Meteorology announced
today. Furthermore, the northern wet season was
very dry and hot in southwest Queensland and northwest NSW.
For the 4-month period from January to April,
serious to severe rainfall deficiencies have developed over an area of eastern Queensland
near and to the west of the Great Dividing Range, stretching from near Moranbah
to around Gympie. Serious to severe rainfall deficiencies have also
developed along the NSW coast south of Sydney, over an area of inland
south-central NSW centred on Grenfell, and some small areas in far
southwest Queensland and adjacent northwest NSW.
Above-normal April rainfall has eliminated short-term rainfall deficiencies
in northern and central Tasmania, except for a small area in the far northeast.
April rains have also removed small areas of rainfall deficiencies that
had existed in northern South Australia and the southern Northern Territory.
For the 7-month period from October to April,
serious rainfall deficiencies, with patches of severe deficiencies,
affect substantial areas in far southwest Queensland and adjacent far northwest NSW.
The dry conditions have been exacerbated by
very much above average to record high temperatures, particularly during the summer.
Deficiencies in the Mackay area have been eliminated by April rainfall.
Above-normal rainfall in April has eliminated nearly all longer-term rainfall deficiencies
that had existed in southern Victoria for the period commencing in April 2005. This
period is no longer being monitored.
Rainfall deficiency
maps for longer periods indicate that deficiencies at the
three year timescale, which are particularly relevant to water supplies,
remain prevalent in parts of eastern Australia, especially in Queensland.
Note: The terms used to describe rainfall in these
Drought Statements have the following meanings -
Serious deficiency
- rainfalls in the lowest 10% of historical totals,
but not in the lowest 5%
Severe deficiency
- rainfalls in the lowest 5% of historical totals
Lowest on record
- lowest since at least 1900 when the data analysed begin
Very much below average
- rainfalls in the lowest 10% of historical totals
Below average
- rainfalls in the lowest 30% of historical totals,
but not in the lowest 10%
- rainfalls in the middle 40% of historical totals
Above average
- rainfalls in the highest 30% of historical totals,
but not in the highest 10%
Very much above average
- rainfalls in the highest 10% of historical totals
For more information regarding this rainfall
deficiencies statement, please contact the following
climate meteorologists in the National Climate Centre:
External Sites Relating to Drought
The Bureau of Meteorology does not make formal drought declarations
as these are done by either the relevant State Governments or by the
Australian Government. The Australian Government Program is called
Exceptional Circumstances
and it is administered by the Federal Department of Agriculture,
Fisheries and Forestry (DAFF). General information about Australian
Government drought assistance is available at
This page was created at on
© Copyright Commonwealth of Australia , Bureau of Meteorology (ABN 92 637 533 532) | Disclaimer | Privacy | Accessibility


text:
FRUITLAND, Md.- A weekend traffic stop south of Fruitland has led to the arrests of two Colorado men on drug charges.
The Wicomico County Sheriff's Office said that shortly after 5 a.m. Sunday, a deputy stopped a vehicle for traveling 92 mph in a 65 mph zone on U.S. Route 13 at Stockyard Road. Police said that upon contacting the driver, 29-year-old Adam R. Gotchey of Denver, Colo., the deputy learned that Gotchey and his passenger, 27-year-old Sean Pierre LaClair of Dillon, Colo., were in a hurry to get to Virginia Beach, Va. The deputy also learned that the duo was traveling from New York City.
According to police, the deputy noted the absence of any luggage in the vehicle. Based on what the deputy deemed as suspicious indicators, a drug K9 team was called to the scene. During the scan, police said the K9 alerted to the presence of the odors of drugs. Police said that during the subsequent search of the vehicle, the deputy located hashish, marijuana and methadone. A search of LaClair's person revealed marijuana, investigators said.
LaClair and Gotchey were arrested and charged with possession of CDS and possession of drug paraphernalia. Both were ordered held in the Wicomico County Detention Center in lieu of $20,000 each.
The 14th Annual Delmarva Bike Week is underway.
All content © Copyright 2000 - 2014 Worldnow and WBOC. All Rights Reserved. For more information on this site, please read our Privacy Policy and Terms of Service


text:
Hologic Appoints Mark D. Myslinski as Senior Vice President and General Manager of DiagnosticsJanuary 31, 2011 1:31 am | by Bio-Medicine.Org | Comments
BEDFORD, Mass., Jan. 31, 2011 /- Hologic, Inc. (Hologic or the Company) (Nasdaq: HOLX ), a leading developer, manufacturer and supplier of premium diagnostics products, medical imaging systems and surgical products dedicated to serving the healthcare needs of women, is pleased to announce...
Endo Pharmaceuticals Announces Receipt of Paragraph IV CertificationJanuary 30, 2011 11:35 pm | by Bio-Medicine.Org | Comments
CHADDS FORD, Pa., Jan. 31, 2011 /- Endo Pharmaceuticals (Nasdaq: ENDP ) announced today that its partners, Teikoku Seiyaku Co., Ltd. and Teikoku Pharma USA, Inc., have received a Paragraph IV Certification Notice from Mylan Technologies Inc. advising of the filing of an Abbreviated...
Cadence Makes Big Addition to Pain-Relief ArsenalJanuary 30, 2011 11:32 pm | by San Diego Business Journal | Comments
Befitting the company's name, San Diego-based Cadence Pharmaceuticals Inc.'s sales staffers are marching to appointments to get a share of the pain-relief business at the nation's hospitals.
HEALTHY IMPACTJanuary 30, 2011 10:32 pm | by San Diego Business Journal | Comments
Health care reform may be a permanent fix to provide every American with basic medical services, but look to temporary staffing firms to do a lot of the heavy - and challenging - lifting on the patient care recruitment front.
Study finds little decline in hepatitis C infections among injection drug usersJanuary 30, 2011 9:33 pm | by EurekAlert | Comments
(Infectious Diseases Society of America) A recent 20-year study of injection drug users in Baltimore found a significant decline in new cases of HIV infection but only a slight decline in new cases of hepatitis C virus (HCV) infection. The findings suggest that efforts to curb...
Despite China's might, US factories maintain edgeJanuary 30, 2011 7:45 pm | by PAUL WISEMAN - AP Economics Writer - Associated Press | Comments
U.S. factories are closing. American manufacturing jobs are reappearing overseas. China's industrial might is growing each year.And it might seem as if the United States doesn't make world-class goods as well as some other nations."There's no reason Europe or China should have the fastest...
Caraco Pharmaceutical Laboratories, Ltd. Reports Results for the Third Quarter and First Nine Months of Fiscal Year 2011January 30, 2011 1:31 pm | by Bio-Medicine.Org | Comments
DETROIT, Jan. 30, 2011 /- Caraco Pharmaceutical Laboratories, Ltd. (NYSE Amex: CPD ) generated net sales of $40.4 million and $268.2 million in the third quarter and first nine months of its Fiscal Year 2011, respectively, as compared to $52.0 million and $178.4 million, respectively, for...
Scripps Research scientists reveal key mechanism governing nicotine addictionJanuary 30, 2011 9:34 am | by EurekAlert | Comments
(Scripps Research Institute) Scientists from the Florida campus of the Scripps Research Institute have identified a pathway in the brain that regulates an individual's vulnerability to the addictive properties of nicotine. The findings suggest a new target for anti-smoking therapies.
Silicon laboratories expands timing solutions with acquisition of SpectraLinearJanuary 28, 2011 6:32 pm | by I-Micronews | Comments
Silicon Laboratories Inc. (Nasdaq: SLAB), a leader in high-performance, analog-intensive, mixed-signal ICs, today announced the acquisition of Silicon Valley-based SpectraLinear, a late-stage private company offering integrated timing solutions. Silicon Labs acquired the talented...
University Receives $5.8M for Stem Cell ResearchJanuary 28, 2011 4:34 pm | by San Diego Business Journal | Comments
The California Institute for Regenerative Medicine, aka CIRM, has awarded three grants totaling nearly $5.8 million to researchers at UC San Diego.
Ambrilia Biopharma stock to be delisted; shares plunge over 60 per cent on TSXJanuary 28, 2011 12:45 pm | by The Associated Press | Comments
Stock in Ambrilia Biopharma Inc. (TSX:AMB) plunged more than 55 per cent Friday after the insolvent biotech company announced it would not challenge a move to delist it from the Toronto Stock Exchange.At the company's request, the TSX agreed to allow the shares to trade for 48 hours before...
BioTime acquires biotech company assets for $250KJanuary 28, 2011 12:45 pm | by The Associated Press | Comments
BioTime Inc. said Friday it has acquired substantially all the assets from biotech company Cell Targeting Inc. for $250,000, a move aimed at bolstering its slate of embryonic stem-cell therapy products.BioTime issued 261,959 common shares as part of the deal and its stock fell 62 cents, or 7.6...
Vitamin D deficiency alters lung growth and decreases lung functionJanuary 28, 2011 12:36 pm | by EurekAlert | Comments
(American Thoracic Society) Previously linked to the severity of asthma and chronic obstructive pulmonary disease in humans, vitamin D deficiency has now been shown to alter lung structure and function in young mice. The new study, conducted by researchers in Australia, offers the...
Lilly Alzheimer & #8217;s Imaging Agent Gets a Conditional Panel VoteJanuary 28, 2011 12:35 pm | by U.S. Food & Drug Administration | Comments
An FDA advisory committee said an Eli Lilly contrast agent that may be useful in predicting Alzheimer's disease could be approved if the company conducts physician training to make sure brain scans are read consistently.
FDA & #8217;s Pediatric Grant Program Addresses Crucial Unmet NeedsJanuary 28, 2011 12:34 pm | by U.S. Food & Drug Administration | Comments
Developers of devices to address unmet pediatric needs may qualify for a piece of a $2.5 million FDA grant.


text:
Kowloon Walled City was home to 50,000 residents and was controversial since 1898, when it was the only part of Hong Kong which the imperial Chinese government refused to hand over to the British. Throughout the chaos of the 20th century, mainland governments of whatever hue maintained that the site was sovereign Chinese land. It became a lawless area, a favourite base for illegal immigrants and famous for its prostitutes, opium dens and unlicensed dentists. The British and Chinese governments eventually agreed the Walled City's fate in 1987 and it was demolished in 1993.
Kowloon Walled City
What was it really like living in Kowloon Walled City?
25 Apr 2013
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- Hong Kong Occupy Central leaders promise civil disobedience campaign in Hong Kong Sep 1, 2014|1:56
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- China Unseen footage of Tiananmen Square attack caught on CCTV Aug 24, 2014|0:29
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Sign up for Yardbarker's daily Top 10 newsletter, the Morning Bark! Customize to get news on your favorite sports and teams.
Found November 21, 2012 on NESN.com:
PLAYERS: JD Drew, Stephen Drew, Jose Iglesias, Derek Jeter, Jim Bowden, Jhonny Peralta
TEAMS: Boston Red Sox, Oakland Athletics, New York Yankees, Detroit Tigers
TEAMS: Boston Red Sox, Oakland Athletics, New York Yankees, Detroit Tigers
One year removed from the J.D. Drew era in Boston, the Red Sox might be taking a look at the family tree. The Red Sox are among the teams interested in Stephen Drew (older brother of J.D.), according to CBSSports.com's Jon Heyman. The Yankees and Tigers reportedly are also interested in the 29-year-old shortstop. Drew is currently a free agent, as the Athletics in October declined their half of a $10 million mutual option. The shortstop was traded to Oakland from Arizona in August after spending his first six-plus seasons with the Diamondbacks. As Heyman points out, the A's could still be interested in signing Drew in what is a relatively weak shortstop market, but clearly the price tag that came with the option was much too high. The Red Sox' shortstop situation is well-documented around Boston. Jose Iglesias, a young defensive wizard, could take the reins up the middle in 2013, but he'll need to show that he's capable of overcoming his offensive shortcomings. The Yankees, meanwhil...
Original Story: http://nesn.com/2012/11/report-red-so...
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Adding Stephen Drew Would Provide Detroit Tigers With Options; Ideal Upgrade at Shortstop
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What Jonny Gomes Means to the Red Sox
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Red Sox Rumors: Kyle Lohse, Josh Hamilton, Hiroki Kuroda
Free agent news: Drew and Berkman
Tigers interested in Stephen Drew and trading Jhonny Peralta?
Red Sox ink Jonny Gomes to two-year deal
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Your Morning Dump...where the Sox are ahead of schedule
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Jonny Gomes and Red Sox nearing two-year deal
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text:
Polsinelli Podcasts - Best Kept Secrets of the Americans WIth Disabilities Act
Marijuana in the Workplace
5 Risks of Telecommuting (And How Employers Should Handle Them)
Pizza Delivery Company Unlawfully Refused Job Coach for Worker With Intellectual Disability and Then Fired Him, Federal Agency Charges -
PHOENIX - PJ Utah LLC, PJ Cheese, Inc., and PJ United, Inc., collectively doing...more
Federal Agency Charges Concrete Company Refused to Accommodate Payroll Manager, Then Fired Her Because of Disability -
HOUSTON - Baker Concrete Construction, Inc. violated federal law by refusing to accommodate and...more
Cities Have an Obligation Under the ADA -
The Ninth Circuit recently ruled that cities have an obligation under the Americans with Disabilities Act to provide on-street parking that is accessible to people with...more
In an important decision for retailers and other public accommodations, the Tenth Circuit overturned a lower court decision requiring that every "porch-like" entrance to Hollister retail establishments be remediated to be...more
Workplace accommodation issues under the Americans with Disabilities Act (ADA) can be tricky to navigate especially if the employee's supporting medical documentation is insufficient. This often occurs in situations where the...more
On July 14, 2014, the Equal Employment Opportunity Commission ("EEOC"), by a 3-to-2 vote of commissioners, issued Enforcement Guidance on Pregnancy Discrimination and Related Issues (the "Guidance"), along with a question and...more
The Equal Employment Opportunity Commission (EEOC) recently issued new enforcement guidance on pregnancy discrimination for the first time in 30 years. The new guidance clarifies the EEOC's understanding of the law, as well...more
A federal appellate court upheld the dismissal of a lawsuit alleging that a Dairy Queen franchisee failed to reasonably accommodate a blind employee under the Americans with Disabilities Act (ADA). In Bunn v. Khoury...more
The answer seems obvious. The employer must decide what hours of work are best for producing its products or serving its customers, and employees must maintain regular and reliable attendance during those hours. In fact,...more
The laws prohibiting disability discrimination impose obligations on employers which go far beyond the mere avoidance of discrimination. In addition to refraining from discrimination, employers must also provide reasonable...more
Employee With MS Denied Accommodation and Fired, Federal Agency Charged -
CLEVELAND - Lifecare Medical Services, Inc., an Ohio medical transportation services company, will pay $72,500 and provide other relief in order...more
In EEOC v. Ford Motor Company, the federal Sixth Circuit appellate court (covering Kentucky, Michigan, Ohio, and Tennessee) recently held that telecommuting may be a reasonable accommodation under the Americans with...more
On Friday, the EEOC filed a lawsuit against AutoZone targeting the company's "no fault" attendance policy because of its negative impact on disabled employees requesting accommodations. The suit, EEOC v. Autozone, Inc., No....more
On Friday, the EEOC filed suit against AutoZone, alleging that the car repair company violated the Americans With Disabilities Act by applying its attendance policy in a way that failed to accommodate certain...more
Jacobsen v. New York City Health and Hospitals Corp., No. 2014-34 (N.Y. Court of Appeals, Mar. 27, 2014): New York's highest court recently ruled that an employer's failure to engage in a good-faith interactive process...more
A California federal court denied Walgreen Co.'s motion for summary judgment on April 11, 2014, in a disability discrimination case brought by the Equal Employment Opportunity Commission (EEOC v. Walgreen Co., 2014 U.S. Dist....more
While the 2008 amendments to the Americans with Disabilities Act ("ADA") made it easier for employees to state a claim that he or she was "regarded as" having a disability, a recent decision from a federal court highlights...more
Good employers often attempt to provide support for employees who are facing personal issues. Such was the case when Selena Hancock developed a nerve condition that prevented her from lifting more than 20 pounds. Although an...more
In recent years, many employers have shied away from telecommuting programs and arrangements, believing employees cannot perform their jobs as effectively from home or be adequately supervised while working remotely. Disputes...more
In a decision that is both favorable to and disadvantageous for New York State employers, the New York Court of Appeals has ruled that indefinite leave is not a reasonable accommodation for persons with disabilities under the...more
Hospital Refused to Accommodate Nurse's Disability, Refused to Reassign, Then Terminated Her, Federal Agency Charged -
TAMPA, Fla. - Saint Joseph's Hospital, part of the BayCare Health System, the second-largest...more
More than 100 nearly identical class action lawsuits alleging noncompliance with Americans with Disability Act accessibility standards for ATM machines have been filed against banks and credit unions since new standards went...more
The New York Court of Appeals – New York's highest court – is out with a new decision this week addressing our favorite statutory friend (foe?), the New York City Human Rights Law – this time in the context of a disability...more
We are in Montana and a very obese woman recently applied for a manager position. The position is more physical than most in that there is significant walking between facilities, and the candidate must climb ladders to view...more
Health Care System Fired a Pulmonary Function Technologist After She Requested an Accommodation and Filed a Discrimination Charge, Federal Agency Charges -
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text:
Angela Lergo, I give you my heart
Intimately impersonal
Grizzly Bear - August March
Wash the taste of me right out of your mouth
Two days left. I've been neglecting exercise so I've gotta get back in the habit of running. There's too many good bands playing here this semester. Everything goes really fast. My writing is still shit. Grizzly Bear is great when you wanna fade away.
(Source: lady-butter, via milk-sockets)
By Michael Donovan
(Source: nikolawashere, via fiebre)
(via hotaruhaku)
(via eldiariodenadie)
A beautiful moon.
(Source: 333.kachiky.net)
(Source: yokotanji)
(Source: thisissen)


text:
Comment: Debian GNOME needs some attention (Score 1) 163
After something like 20 years I finally found a system that won't run Debian unstable right now. My Panasonic Toughpad FZ-G1 magnesium tablet + iKey Jumpseat magnesium keyboard. Systemd and GDM break. Bought (for less than full price) because I am a frequent traveler and speaker and really do need something you can drop from 6 feet and pour coffee over have it keep working.
But because of this bug I have ubuntu at the moment, and am not having fun and am eager to return to Debian.


text:
With a new bundle of joy starring in your world, there is no doubt you'll be "showered" with all kinds of love, encouragement, support and gifts, and our line of Baby Announcements & Stationery is here to help. Fashioned in all the cutest baby boy and baby girl designs, this beautiful stationery will make it easy for you to write all your thank you's and invite all your friends and family to the events you'll cherish the most in their first years!
Baby Announcements & Station
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oPatientPlus articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use, so you may find the language more technical than the condition leaflets.
Torsades de pointes is a distinctive polymorphic ventricular tachycardia in which the QRS amplitude varies and the QRS complexes appear to twist around the baseline. Torsades de pointes is associated with a prolonged QT interval, which may be congenital or acquired. It is usually not sustained and terminates spontaneously but frequently recurs unless the underlying cause is corrected. Torsades de pointes may degenerate into sustained ventricular tachycardia or ventricular fibrillation.[1] Torsades is a life-threatening arrhythmia and may present as sudden cardiac death in patients with structurally normal hearts.
- The corrected QT interval is longer in the white population than in the black population, and longer in females than males. Therefore, torsades de pointes is more common in white races and in females.
- Torsades occurs at any age. If it occurs at an early age, the cause is usually due to congenital long QT syndrome. In later years, the cause is usually due to acquired long QT syndrome.
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Risk factors[2]
- Congenital long QT syndromes, eg Jervell and Lange-Nielsen syndrome, Romano-Ward syndrome.
- Acquired long QT syndromes:
- Acute myocardial infarction.
- Drugs, eg antiarrhythmic agents of classes Ia and III, erythromycin, ketoconazole, tricyclic antidepressants, antipsychotics.
- Electrolyte disturbances; hypokalaemia, hypomagnesaemia, hypocalcaemia.
- Renal failure, liver failure.
- Metabolic; hypothyroidism, anorexia nervosa, starvation.
- Bradycardia; sinoatrial disease, atrioventricular (AV) block.
- Toxins; heavy metals, insecticides.
- Episodes of torsades in patients with congenital long QT syndromes may be triggered by stress, fear or physical exertion.
- Patients with torsades usually present with recurrent episodes of palpitations, dizziness, and syncope.[3] Sudden cardiac death can occur with the first episode.
- Nausea, pallor, cold sweats, shortness of breath and chest pain may occur.
- A history of congenital deafness or a family history of sudden death may indicate a long QT syndrome.[1]
- Physical findings depend on the rate and duration of tachycardia and the degree of cerebral hypoperfusion. Findings include rapid pulse, low or normal blood pressure, and transient or prolonged loss of consciousness.
- Other physical signs depend on the cause, eg features of a congenital disorder.
Differential diagnosis
- Ventricular tachycardia.
- Supraventricular tachycardia with aberrant conduction.
- Other causes of syncope or sudden cardiac death.
- Paroxysms of 5-20 beats, with a heart rate faster than 200 beats per minute. Sustained episodes are occasionally seen.
- Progressive change in polarity of QRS about the isoelectric line occurs with complete 180° twist of QRS complexes in 10-12 beats.
- Usually, a prolonged QT interval and pathological U waves are present. The most consistent indicator of QT prolongation is a QT of 0.60 seconds or longer or a QTc (corrected for heart rate) of 0.45 seconds or longer. QTc = QT interval divided by the square root of the interval (in seconds) between the onset of each QRS complex (Bazett's formula).
- A short-long-short sequence between the R-R interval occurs before the trigger response.
- Electrolytes; hypokalaemia, hypomagnesaemia and hypocalcaemia.
- Cardiac enzymes; assessment for myocardial ischaemia.[2]
- CXR and echocardiography, to rule out structural heart disease.
Short-term treatment
- Resuscitation
- Defibrillation:
- Although torsades is often self-terminating, it may develop into ventricular fibrillation, which requires defibrillation.
- In an otherwise stable patient, direct current (DC) cardioversion is usually a last resort because torsades is paroxysmal in nature and frequently recurs after cardioversion.
- Discontinuation of any offending agent (stop all QT-prolonging drugs) and correction of any underlying cause such as hypokalaemia, hypomagnesaemia and bradycardia.
- Intravenous magnesium is the drug of choice for torsades de pointes. Magnesium is effective even in patients with normal magnesium levels.
- Acceleration of the heart rate can be achieved by using beta 1-adrenergic agonists such as isoprenaline or overdrive electrical pacing.[1]
- Isoprenaline is used as an interim treatment until overdrive pacing can be started:
- Isoprenaline accelerates AV conduction and decreases the QT interval.
- It can be used in bradycardia-dependent torsades that is usually associated with acquired long QT syndrome.
- Isoprenaline is given as a continuous intravenous infusion to keep the heart rate faster than 90 beats per minute.
- Beta-adrenergic agonists are contra-indicated in the congenital form of long QT syndrome.
- Temporary transvenous pacing:
- Pacing can be effective in terminating torsades by increasing the heart rate and so reducing the QT interval.
- Atrial pacing is the preferred mode because it preserves the atrial contribution to ventricular filling. In patients with AV block, ventricular pacing can be used to suppress torsades.
Long-term treatment
- Patients without syncope, ventricular tachyarrhythmia or a family history of sudden cardiac death can be observed without starting any treatment.
- Congenital long QT syndrome:
- Beta-adrenergic antagonists are used as a first-line long-term therapy in congenital long QT syndrome. Propranolol is has been the most extensively used.
- Betablockers are contra-indicated in acquired cases because bradycardia produced by these agents can precipitate torsades. They should also be avoided in those congenital cases in which bradycardia is a prominent feature.
- Permanent pacing benefits patients who remain symptomatic despite receiving the maximally tolerated dose of betablockers and can be used in addition to betablockers.
- High left thoracic sympathectomy is effective in patients who remain refractory to beta-blockade and pacing.
- Implantable cardioverter-defibrillators (ICDs) are useful in rare instances when torsades still continues despite all of these treatments. Betablockers should be used along with ICDs because shock can further precipitate torsades by adrenergic stimulation.
- Acquired long QT syndrome:
- Long-term treatment in acquired cases is usually not required because the QT interval returns to normal once the predisposing factor has been corrected.
- Pacemaker implantation is effective in cases that are associated with heart block or bradycardia.
- Implantable cardioverter-defibrillators are indicated in cases that cannot be managed by avoidance of any specific precipitating factor.
- Ventricular tachycardia
- Ventricular fibrillation
- Sudden cardiac death
- Patients may revert spontaneously or convert to a non-polymorphic ventricular tachycardia or ventricular fibrillation.
- Torsades is a life-threatening arrhythmia and may present as sudden cardiac death in patients with structurally normal hearts. In congenital long QT syndrome, the mortality rate for untreated patients is 50% in 10 years, which can be reduced to 3-4% with treatment.
- In acquired long QT syndrome, the prognosis is excellent once any precipitating factor has been removed.
- Avoid offending drugs that prolong the QT interval.
- Prevent predisposing conditions such as hypokalaemia, hypomagnesaemia, and hypocalcaemia, especially in patients shown to have long QT interval.
- Screen families of patients with torsades for whom the cause for prolonged QT is suggested to be congenital.[1]
Further reading & references
- Bessette MJ et al; Torsade de Pointes (Emergency medicine perspective), eMedicine, Jan 2010
- Dave J et al; Torsade de Pointes (Cardiology perspective), eMedicine, Jan 2010
- Brignole M; Diagnosis and treatment of syncope. Heart. 2007 Jan;93(1):130-6.
- ECG Library; © Stephen Gerred (Medical Registrar Auckland, New Zealand) Dean Jenkins (Specialist Registrar, Llandough Hospital, Cardiff, Wales)
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.
Original Author:
Dr Colin Tidy
Current Version:
Dr Colin Tidy
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text:
See and share Beautiful Nature Photos and amazing photos of interesting places
Let dogs delight to bark and bite,
For God hath made them so:
Let bears and lions growl and fight,
For 'tis their nature, too.
But, children, you should never let
Such angry passions rise:
Your little hands were never made
To tear each other's eyes.
Let love through all your actions run,
And all your words be mild:
Live like the blessed Virgin's Son,
That sweet and lovely child.
His soul was gentle as a lamb;
And as his stature grew,
He grew in favor both with man,
And God his Father too.
Now, Lord of all, he reigns above;
And from his heavenly throne
He sees what children dwell in love,
And marks them for his own.


text:
Jenelle Evans, made famous by MTV's Teen Mom, isn't going to win Mother of the Year any time soon, but she is also not that strange for a teenager. Yes, she has problems, but if she hadn't had a child, most of those problems -- drugs, bad boyfriends, depression -- wouldn't be all that different than the ones faced by so many teenage girls and women in their early 20s. So why is her former "friend" Tori selling stories about her cutting?
It's pretty bad that a friend would sell her out, period. But even worse is WHAT she is selling out. Many young girls "cut" and it's not something they would like shared with the world.
The fact is, if it's true, this is a girl in pain and her "friends" are worse than enemies. Maybe Tori NEEDED to be hit.
It's pretty obvious that Jenelle has had problems long before she got pregnant with Jace. Her "friend" said:
[When Jenelle's parents split], it just messed with her head. Sometimes you [could] see the blood and stuff.
This is the problem with getting famous, of course, and Jenelle asked for her life to be scrutinized when she went on a reality show. But realistically, cutting isn't a laughing matter.
It isn't a piece of gossip, though, and it isn't some cry for attention. If Jenelle was cutting, she was doing so because of her bipolar disorder, her family problems, and pain she was trying to express physically. It's sad and a huge problem.
Cutting isn't funny or crazy and my guess is she isn't doing it on purpose to be made fun of (if she is doing it at all).
Jenelle never should have been a mom. She was an at-risk youth who made a permanent change in her life. Now that her son is here, one can only hope she will someday get it together, get better friends, and find new ways of expressing her emotions and dealing with her pain. Cutting isn't the way.
Do you think this story is true?
Image via MTV
I think her dear friend Tori is looking for every bit of attention she can get from this and is spilling out a bunch of crap, and needs to keep her mouth shut.
And somebody needs to give that girl a swift kick in the head.
First of all, Jenelle doesn't need help looking bad she does just fine on her own but this girl is probably trying to make a quick buck and while I think that is low I think this statement in the artice is lower "Maybe Tori NEEDED to be hit." NO ONE needs to be hit and Jenelle was a terrible friend to Tori and all of her friends for that matter. Jenelle treats everyone around her like trash and feels it's okay for her to cuss out and put her hands on who ever she feels like at the time including her own mother! I hope Jenelle never gets custody of her son because the one time he mouths off to her she'll probably put her hands on him too... I hope someone eventually presses charges against her so she can feel the full repercussions of her actions. I think it's hilarious that she verbally/physically abuses everyone around her including boyfriends but then is quick to press charges on them for grabbing her and sing little songs about domestic abuse like she's a freakin victim! Girls like her give true victims a bad name. Maybe Tori is low for releasing that info but as far as I'm concerned it's Jenelle's just desserts!
BTW, what hard life??? She's a spoiled brat her creates her own problems and then whines about them. Her mom may be far from perfect but she financially supported Jenelle's pregnancy, stepped up and took care of her son so she could go out a party, has bailed her out on multiple occasions, let her live with her despite the drama she brings, and much much more. Jenelle's demons are self created and I feel no pity for her what-so-ever. If she is cutting, it's probably for the attention in which case Tori is helping her.
Sorry, don't feel sorry for her. I feel sorry for our future. As these young people are our future, I fear we have no future. Because of bleeding hearts, our futures are being raised w/o dicipline, restraint and not giving in to stupid urges. The boys won't keep it in their pants and the girls won't keep their legs closed. Can't call them young men and women, because they all act like spoiled 5 y/o. who have never ever been punished for anything. She gets what she deserves!!!! And no, SHE IS NOT A GOOD MOTHER!!!!!


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Corner Baths
A corner bath makes a dramatic statement in your bathroom and creates plenty of bathing space too. Any one of our stylish corner baths will instantly give your bathroom a lift. Go for glamour with luxury brassware and waterfall taps, to give your corner bath a spa like feel. Or try an efficient single bath tap with mixer to make your corner bath ideal for a shared family bathroom. Read more ...
Corner Baths Provide Stylish Bathing
Corner baths are ideal for a smaller bathroom, allowing a great deal of space to be saved within the bathroom and ensuring that there is plenty of room for the other essentials required. As well as saving space within the other three corners of your bathroom, dedicating one corner purely to your bath allows for an extremely spacious and relaxing bathing experience, similar to the more traditional freestanding baths.
Corner Bath Design Choices
Screwfix Bathrooms are experts when it comes to the design of bath suites, and can provide you with a corner bath to suit any bathroom.
Whether you are putting together a hectic family bathroom or a luxurious bathing space for you and your partner, a corner bath is a superbly stylish addition. Both left handed and right handed corner baths are available, ensuring that you can rely on Screwfix Bathrooms to provide exactly what you need to put together the bathroom of your dreams. One popular option is the Solar Corner Bath, which comes with a capacity of 160 litres, as well as using Supercast, which is designed for extra strength and warmth in your bathtub.
Corner Baths from Screwfix Bathrooms
If you have a question about your purchase of a corner bath from Screwfix Bathrooms, don't hesitate to get in touch. You can call us on 0800 954 1646, or email email@example.com.
Many of the answers to your queries may well be found within the Screwfix Bathrooms Bath Buying Guide, which contains a number of helpful hints when deciding which bath is best for your preferences.


text:
Feiss Wall Lights
There is a difference between having lights and having lighting. Choose a Feiss Wall Light for your home that adds flair and style. There are multiple styles from which to choose, constructed with different materials, such as metal or wood. Pick one that complements the cozy feeling of your home.


text:
ABC News Promotes Eric Avram and Santina Leuci
ABC News has promoted a pair of executives charged with wrangling tough interviews. Eric Avram has been promoted to Senior EP of division-wide interviews, reporting to ABC News president Ben Sherwood. In that role Avram will be in charge of interviews for ABC's Medical, Business and Law & Justice teams as well as the Woodruff unit and the investigative units.
Santina Leuci, "Good Morning America'"s chief booker, will become executive editorial producer, while retaining her "GMA" duties. She will continue to report to "GMA" senior EP Tom Cibrowski.
Avram has been the man charged with booking big guests for many of ABC's primetime specials. As the network moved away from paying for interviews via license fees, it has been able to book big guests by promising maximum exposure on multiple platforms and shows. Leuci has been at the forefront of "GMA'"s revival, particularly during Robin Roberts' absence from the program, when a number of big names stepped in to help fill her shoes.
Sherwood's note to staff, after the jump.
Read more


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Sandy • Six games don't make a season. One year doesn't equal a career. But after taking a chance June 27 on little-used and often-forgotten defender Kwame Watson-Siriboe, Real Salt Lake has gladly accepted everything it has received.
While RSL has often struggled in its last five games, losing three and being blown out 5-0 by San Jose, Watson-Siriboe has exceeded expectations. Exiled by the Chicago Fire for more than a year, the 25-year-old centerback is finally approaching the potential first shown when he helped lead the University of Connecticut twice to the NCAA Tournament quarterfinals.
Real's defense hasn't always been lockdown since Watson-Siriboe joined via a trade with Chicago for a fourth-round pick in the 2014 MLS SuperDraft. But RSL's uneven play has obscured an attack that's held opponents to just three combined goals in four games, including a 2-0 shutout of Colorado Rapids on July 21.
"As a team, we practice defense first. And once we're defending well as a team, then we know that through our possession and our play, we'll probably get goals," Watson-Siriboe said. "From the coaching staff and above, they tell us defense first. Once we get that down pat, then we can attack the other team."
The 6-foot-3, 196-pound Watson-Siriboe has played a key role in Real's recent stinginess. He played 90 minutes during his RSL debut July 4 against Seattle. In six games, he's totaled 378 minutes and four starts. For a tall, muscular player who prides himself on his athleticism, simply holding a relevant role in Real's outcome has been a life-changer. Watson-Siriboe went from Oct. 23, 2010, to June 30 without even entering an MLS match
"It definitely wasn't [easy]," said Watson-Siriboe, who spent 2011 in the second-tier North American Soccer League. "Coming from college, you're comparable to a lot of players. But coming into the league, MLS players are very technical, very athletic. … It was something that was my dream, so I continued to keep going. If something doesn't happen right away, you shouldn't get discouraged if it's something you truly love to do."
Watson-Siriboe knew all he needed was a chance. So did Real assistant coach C.J. Brown. When RSL had an opportunity to land Watson-Siriboe, Brown pushed hard. Now that the defender is beginning to prove he can consistently compete at the MLS level, Brown wants more.
"The sky's the limit for him, as long as he has the right mentality," said Brown, who's provided his ex-Fire teammate with RSL game tape in an effort to fast-forward his development.
He added: "It's about staying hungry. One game, you have a good game, that means nothing. I need you to do that the next game. I need it in training, and I need to see the focus and the determination. If you don't show that in training … that, to me, tells me you're not ready."
RSL coach Jason Kreis also isn't settling. Watson-Siriboe's been "solid," running on fresh legs that have provided much-needed energy. But high expectations have defined RSL's up-and-down season, and Kreis said this isn't the time for his team or Watson-Siriboe's career to be content.
"There's a lot of emotion that he's been riding so far and doing a good job," Kreis said. "But we need to be very careful, because this is only four or five games for a very young player."
RSL at Vancouver
P At BC Place (Vancouver)
Kickoff • Saturday, 5 p.m.
TV • Ch. 4
Radio • 700 AM
Records • RSL 13-8-3, Vancouver 9-7-7
TheWatson-Siriboe file
Position • Defender
Year • 3
Vitals • 6-foot-3, 196 pounds
Stats • 6 games, 4 starts, 378 minutes
Career • 16 games, 11 starts, 1,059 minutes, three shots on goal
College • Connecticut
Born • Chino Hills, Calif.


text:
Landmines killed nine people in Afghanistan in two separate incidents on Sunday.
KABUL, Afghanistan — Officials say landmines have killed nine civilians in separate incidents in eastern and southern Afghanistan.
Youqib Khan, who is deputy police chief for the eastern Khost province, said three men, two women and a baby died when their vehicle ran over a mine as they were returning home from hospital on Sunday morning. The family was leaving a maternity hospital in Khost province in a pick-up truck when the bomb exploded, a statement from the office of the provincial governor said.
"A pregnant woman was taken by her family to a hospital last night at 10 p.m, and they were making their way home in the morning with their newly born baby when the bomb hit," said Zarmaeed Mokhlis, governor of Khost's Sabari district.
In the south, three civilians were killed when their vehicle detonated a landmine Sunday on the road between Helmand and Kandahar provinces, a government statement said. Two other members of the family, which was on the way to a wedding, were wounded.
The United Nations says homemade bombs continue to be the deadliest weapon for civilians in the war.
Meanwhile, a U.S. soldier was killed by an improvised explosive device in southern Afghanistan on Saturday, a military statement said. It did not elaborate.


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getting my patsy on in most ways…already more than halfway through the bottle..got my bouf goin too. yummy cab sav btw and ignore my grim reaper shirt haha
posted 8:41 pm on Saturday, June 18, 2011 with 12 notestags » #gpoy #thanks patsy #patsy stone #wine #kinda drunk
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See you in hell, my friend.
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Remington College in Oahu is in the heart of downtown Honolulu, amid restaurants and local businesses. Yet just five blocks away, you can see the crystal clear Pacific Ocean.
Just like the bustling downtown area we're a part of, our College means business when it comes to educating our students. And just like the blue waters of the nearby ocean have the power to invigorate you, the environment at our Campus is all about stimulating your senses and revitalizing your full potential through the power of education.
Call or request information to see our Honolulu college for yourself.
Remington College's Honolulu Campus offers Bachelor's, Associate's and Diploma programs. Programs offered include: Criminal Justice, Clinical Medical Assisting and Massage Therapy.If you would like to talk to a Remington College Admissions Representative about the Honolulu Campus please call
Start Today! Call:
(1) Employment upon graduation not guaranteed.
Copyright © 2014 Remington College. All rights reserved.


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Fallen Marine's funeral today in Frederick
Frederick and Washington counties will today say goodbye to Marine Lance Cpl. Maung "Sam" Htaik, 20, who was killed in combat in Afghanistan on Jan. 1.
Tags: Maung "Sam" Htaik , Smithsburg High School , Marine , Funeral ,
Military center heart of 'secret war' on terror
AP reports on the center that will be staffed by 100 special operations agents.
Tags: DoD Report , terrorism , military , secret war , CIA , cloud computing , Dorobek Insider , technology
1,400 more Marines headed to Afghanistan
The battalion could start arriving as early as mid-January, and would mostly be deployed in the south, around Kandahar.
Tags: troop deployment , Robert Gates
New drones to be deployed in Afghanistan
The Gorgon Stare drone has nine cameras and can monitor a whole city
Tags: Federal Drive , Defense , DoD Report , Gorgon Stare ,
Corruption investigations in Iraq, Afghanistan on the rise
Stuart Bowen, Special Inspector General for Iraq Reconstruction, discusses why alleged fraud cases seems to be increasing in the war zones.
Tags: Stuart Bowen , DoD , Iraq , inspector general , corruption , accountability , Federal Drive , contracting
Commander: Afghan-Pakistan border impossible to seal
A senior U.S. commander said the focus is now fighting Taliban militants in Afghanistan.
Tags: DoD Report , Associated Press , Pakistan , Taliban , military , Viet Luong , Federal Drive
DoD awards $1B contract for Afghan training
DynCorp International will provide support to 14 training facilities in Afghanistan.
Tags: DoD Report , DynCorp International , contracting , Federal Drive
Flournoy, Cartwright on Afghanistan, Pakistan, and Korea
Pentagon leaders say relationship with Pakistan is central to U.S. efforts in Afghanistan.
Tags: In Depth , Francis Rose , Michelle Flournoy , James Cartwright , management , DoD , Pakistan
What needs to be done in Afghanistan?
The Afghanistan and Pakistan Annual Review reaffirms the strategy's "core goal" to disrupt, dismantle, and eventually defeat al-Qaida in the Afghanistan-Pakistan region and prevent its return to either country. We get details from DoD's David Sedney.
Tags: Federal Drive , DoD , Pentagon , Afghanistan and Pakistan Annual Review , David Sedney
Gates gives troops a holiday lift
Four soldiers traveling to see family for the holidays got an upgrade, courtesy of Defense Secretary Robert Gates.
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