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Articles Tagged with ''safety''
Professional tips for building upkeep
Maintaining an attractive and safe environment for carwash customers.
August 29, 2014Read More
Workplace safety violations lead to fine
August 25, 2014Read More
Special Edition Newsletter: Security
January 24, 2014Read More
Got Safety? Part Two
Lustra™ Tip of the Month
March 9, 2011Read More
Safety Orientation
CarWash College™ Tip of the Month
October 29, 2010Read More


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Dutch architecture firm UNStudio has designed a skyscraper for Singapore that looks like a cactus. More »
Tag: UNStudio
V on Shenton
Centre for Virtual Engineering
by UNStudio
The Scotts Tower by UNStudio
Kutaisi Airport by UNStudio
Frank Gehry creates strategic alliance
of leading architects
Dezeen Wire: architect Frank Gehry has invited some of the world's leading architects and designers to join an advisory board that aims to identify ways to achieve a higher quality of built environment through intelligent design. More »
Observation Tower by UNStudio
New Amsterdam Pavilion by UNStudio
Education Executive Agency & Tax Offices by UNStudio
New Amsterdam Chair by UNStudio
for Wilde + Spieth
Milan 2011: Dutch architects UNStudio will present this angular white plastic chair at the Salone Internazionale del Mobile in Milan this week. More »
Galleria Centercity by UNStudio
SitTable by UNStudio for Prooff
At Interieur 2010 in Kortrijk this week Amsterdam architects UNStudio present a set of two tables that incorporate upholstered seats. More »
UNStudio Tower by UNStudio
Living with Books and Art by UNStudio
Dalian Football Stadium by UNStudio
New Amsterdam Pavilion by UNStudio opens
Dezeenwire: the New Amsterdam Pavilion by dutch designers UNStudio opens today in Battery Park, New York. Related: see our previous story about the project.
Dance Palace by UNStudio
Raffles City Hangzhou by UNStudio
Burnham Pavilion by UNStudio
Here are some pictures of the completed Burnham Pavilion by Dutch architects UNStudio in Millennium Park, Chicago. More »
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subset: commoncrawl


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I'm a stage manager; lover of theatre, reading, and music. I'm trying to get my groove back into writing so here it goes.
You don't need religion to have morals. If you can't determine right from wrong then you lack empathy, not religion.
Kane Bailey
(via psych-facts)
I use sarcasm because flat out telling you you're a fucking moron is considered inappropriate and is frowned upon. And I was raised better than that.
and then sometimes you're such a moron I have to go against my better judgement and tell it like it is.
I always crushed on Josh but who didn't love Toby's snark?
(Source: fourpennies)
there are nice americans
there are rude americans
there are nice brits
there are rude brits
there are nice canadians
there's justin bieber
^ all sorts of truth… can we trade him back for Robin Sparkles?
(Source: tom-marvolo-dildo)
Texts are secrets. They're little mementos of inclusion and excitement you can read over and over. They're letters, journal entries, notes passed in class. Because we like to hold onto words that mean something to us. We like re-read and remember and re-live that moment when he said, "I miss you," or even just "Merry Christmas" because you know they mean the same thing…And when I text my best friend, "He texted me! " and she replies, "Yay!", we're not a generation lost staring at screens. We're in corsets being handed scrolls sealed with his coat-of-arms. We're in sundresses waiting for the postman to drop his letter. We're on swing sets hoping to circle 'yes' or 'no.' We're a million starry eyes still staring at the same starry skies with fingers crossed and hopes high.
DateByNumbers No Texting, No Exceptions on CollegeCandy (via datebynumbers)
(Source: faunasworld-moved)
This makes me wish Lea was a friendlier cat. only a little though cause my angry lynx is the coolest ever.
(Source: cute-kitty-cats)
SHIT I CAN'T MAKE UP: Convo between my 7year-old students today
(Names have been altered slightly, just in case.)
Josie: I have a new crusshhhhh
Matt: Me too! On a boy!
Pearl: You're a boy with a crush on a boy?
Matt: Yeah he's really cute.
Pearl: Oh.
(pause for a bit)
Matt: Boys can like boys. I just can't marry him because boys can't marry boys.
Me: Yeah they can. You can marry whoever you want.
Matt: Really?
Josie: YEAH my tia has a wife so now I have a titi and a auntie.
Matt: Okay. Then maybe I'll marry him.
Dave: (from across the room) No you can't you're seven.
(Age was apparently the only foreseeable problem anyone of my elementary schoolers could see with gay marriage. I almost cried out of happiness. Later, when I was asked if boys could kiss anyone they wanted, I replied "only if they want to kiss you back." And Josie responded "Yeah! Your body your life.")
My students are the shit.
seven year olds are smarter than most fully grown adults
(Source: marissalosesit)
kinda like those guys you date that don't understand theatre world.
(Source: fuckyeahthespianpeacock)


text:
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Droppelman promoted at D.A. Davidson
Jennifer Droppelman
Jennifer Droppelman, of D.A. Davidson & Co.'s Bellevue branch, has been named Associate Vice President, Financial Consultant, in recognition of the high quality of service to her clients and the growth of her business.
D.A. Davidson & Co. is the largest full-service investment firm based in the greater Northwest.
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Audits. From the design phase, Hayes knew that a comprehensive, annual audit of the entire security program would be necessary. He wanted an independent third party to conduct the audit but found that none of the applicants for the job met his requirements. "Everyone who bid for the job could analyze risk, but none of them knew anything about the food manufacturing industry," he says.
See all the latest links and resources that supplement the current issue of Security Management magazine.


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Let's peek inside 5 great troop trailers
May 102013
By Bryan
Even the best-looking troop trailer designs can't hide ugly insides. You know the ones I mean: cavernous, unorganized spaces into which gear is deposited and never seen again.
That's why many troops add the Scouting touch to their trailers, installing shelving and other improvements to make storing and finding gear a breeze — even if it's after dark on Friday night when you pull into camp.
So last month, I asked for troops to send me photos of the Read More At The Source
Via: Bryan On ScoutingPrint


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INSTEON for Hub
10,000 - 50,000 downloadsAdd this app to your lists
+ By INSTEON
Download the INSTEON for Hub app, Connect your INSTEON Hub, Select your favorite INSTEON devices for your home and Enjoy!
The INSTEON Hub works in combination with your router and smartphone or tablet to control INSTEON devices in your home while you're there, when you're at work, or out of town.
The INSTEON for Hub app works in concert with the Hub to automatically configure your Hub and router for remote access - so simple, anyone can do it.
Easy Device Scheduling
Want to turn on your bedside lamp automatically to help wake you up in the morning? How about program the porch light to turn on and off automatically with the rise and fall of the sun? No problem.
Get Alerts on Your Mobile Phone or Computer
Create alerts by adding water leak sensors, motion sensors, door/window sensors and more. The INSTEON Hub will send text and email alerts to you as well as anyone else you wish. The Hub also stores the status of these sensors, so you can easily check on your sensors from within the app at anytime.
Stay Connected to What Matters Most
Wonder what triggered the motion sensor or just want to check in on the kids or your pets? Add a wireless camera and you'll see it all from your smartphone. The INSTEON cameras feature pan/tilt control and night vision. Setting up this camera within the INSTEON for Hub app is the easiest setup that you have ever seen!
Cloud-based Service
The INSTEON Hub stores your homes configuration in the cloud which allows access from any number of smartphones and tablets you may own. Add another smartphone by simply downloading the app, sign in and enjoy.
That's right. No monthly fees to view, control and monitor your home. Other systems on the market charge hundreds of dollars a year for services that you can enjoy for free with the INSTEON Hub.
Easy Installation with Videos
The INSTEON for Hub app features video installation wizards that walk you through setup of many INSTEON devices.
Detailed INSTEON app features:
•Simple and clear user controls
•Easy to follow onscreen wizards for fast setup
•INSTEON Thermostat support, temp, humidity, mode, cool, heat, fan
•Supports Venstar thermostat (with INSTEON Adapter)
•Ability to add INSTEON/Smarthome indoor and outdoor IP camera
•IP camera configuration – ability to set username, password, add/edit/delete contrast, brightness, mirror, flip image, directional control (up/down/left/right – ie "pan/tilt")
•Create a scene – single activation with multiple devices
•Create rooms for organization
•Add a timer for on/off/days of week
•Auto-detect of geo-location of smartphone to calculate sunrise/sunset and automatic time synchronization
•Receive SMS/Email alerts when sensors and devices are activated
•Quick status of sensors with the Check-In page
•Cloud service provides access via multiple devices without reconfiguration
•UPnP – ability to setup remote port forwarding for routers that support UPnP
•Works over WiFi, 4G, 3G, and EDGE
•Set schedules for devices for every day of the week
•Supports hundreds of INSTEON devices
•Technical support and feedback email link within the app
INSTEON app requirements:
• Android Phone or Tablet running version 2.2+
• INSTEON Hub
Tags: insteon hub widget, new insteon hub remote setup, insteon for hub, insteon hub setup, insteon hub, how to make insteon hub compatible with x10, insteon for hub apk for tablet, convert insteon smartlinc to hub, prueba virtual insteon para hub, how to setup insteon hub.
FanLinc support
Now with faster load times
Ability to add and monitor temperature of an always-on (plug-in powered) Wireless Thermostat
Ability to add a scene to a keypad button
Improved thermostat interface
(53 stars)
This app as well as the hardware is difficult to setup. If you stand on your head while holding your big toe it may connect but you need a third hand to hold your privates for it to work with hardware. The entire software staff should be fired and some mo
(53 stars)
If I could give this "0" stars I would. Where should I start? I went to home depot and looked at the signs "easy to setup and "wireless". Neither of which is true, nor is stability and range. If you hook this piece of junk up and it finds the guest part o
(53 stars)
Much improved
(53 stars)
I can adjust t-stat, lights, and camera in my house.
(53 stars)
(53 stars)
I set up insteon for hub app on ipad. Added my devices and Nest thermostat. But when I use the same account to login into the app on an Android device, it just crashes when the app opens. Doesn't let me remove nest or do anything else. Just crashes f
(53 stars)
Almost unusable over 3G/4G. Only about half the commands get through and most of the time I cant even status my system. Even over wifi I get this issue about half the time. Would not have done the hub had I known. When it works I love it, but that isnt ev


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We offer undergraduate programs in Physics and Environmental Physics, as well as several joint degree programs with other disciplines. Graduate programs are offered at the M.Sc. level in Physics and Physical Oceanography and at the Ph.D. level in Atomic and Molecular Physics, in Physical Oceanography, in Condensed Matter Physics and in Theoretical Physics.
A mid-summers day party was held to say goodbye to John Whitehead after his several decades in our department.


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After dating for the last 27 years, Tina Turner and Erwin Bach got married in a civil ceremony in Switzerland over the weekend, Reuters reports.
Add new fall shows to your watchlist
The eight-time Grammy winner...read more
Pinetop Perkins, the boogie-woogie piano player, died Monday at his home in Austin, TX, according to his official website. He was 97.
The Mississippi native, who is said to have taught...read more
Five Remain on Survivor: China Theyre tired, irritable and, quite frankly, really look like they need to eat a burger or 10. With only five contestants left, time to start placing your votes as to who is actually going to be crowned Survivor: China. This week, everyone will be duking it out for a overnight trip to the Great Wall and some Mongolian BBQ. Then contestant numero 12 says bye-bye at tribal council. Who will it be? Watch it now! | More online videosSexy Pole Dancers on NYC SubwaysOh, the things people will do to make a buck. On a dare to win a cash prize, four exceptionally limber ladies showed their pole-dancing skills in a place they knew they would be appreciated the NYC subways (the riders faces are priceless). Talk about ballsy! We're really hoping they win a nice chunk of change for their hard work because take it from us those trains arent exactly the cleanest things in the world to grind up against. More online videosS...read more
The last know footage of Ike Turner before he passed. Ike drops some knowledge on Jacky Jasper and it sounds like he speaks from experience... Just ask Tina!
When Tina Turner first met German music producer Erwin Bach in 1986, she says it was love at first sight. Almost 30 years later, Erwin and Tina are now husband and wife. Watch as Erwin shares why it's still difficult for him to hear about Tina's abusive relationship with ex-husband Ike Turner. Plus, Erwin opens up about the first time he proposed to Tina.
Based on a true story centering on 16-year-old Agnes Apple Bailey (Vanessa Hudgens), GIMME SHELTER uncovers the struggle for survival and the hope of redemption through the harsh realities of life on the streets. As a pregnant teenager, Apple s journey plummets her into a perilous struggle until finding salvation in a suburban shelter for homeless teens. With provisions of unprecedented comfort, a collective sisterhood connection and female empowerment, the shelter inspires Apple to break the shackles of her past and inspires her to embrace the future with clarity, maturity and hope not only for herself but her unborn child.
Strippers get asked the darnedest questions. Do I look like your father?
Do I remind you of your father? Fathers and daughters in strip clubs.
Strip club fever. Incest with uncles, cousins, fathers, and daughters.
Ike Turner. Advice from seasoned strippers. Customers from strip clubs
ask the stupidest questions.
Have a question? http://www.stripperfriendly.com
Follow us on FB: http://www.facebook.com/profile.php?id=100001483916106
More Clips & Interviews
Called the greatest rock film ever made, this landmark documentary follows the Rolling Stones on their notorious 1969 U.S. tour. When three hundred thousand members of the Love Generation collided with a few dozen Hells Angels at San Francisco's Altamont Speedway, Direct Cinema pioneers David and Albert Maysles and Charlotte Zwerin were there to immortalize on film the bloody slash that transformed a decade's dreams into disillusionment.
Called the greatest rock film ever made, this landmark documentary follows the Rolling Stones on their notorious 1969 U.S. tour. When 300,000 members of the Love Generation collided with a few dozen Hells Angels at San Francisco's Altamont Speedway, Direct Cinema pioneers David and Albert Maysles and Charlotte Zwerin were there to immortalize the bloody slash that transformed a decade's dreams.
More Ike Turner Movies Videos
More Credits (9)
From the Associated Press:"Ike Turner, whose role as one of rock's critical architects was overshadowed by his ogrelike image as the man who brutally abused former wife and icon Tina Turner, died Wednesday at his home in suburban San Diego. He was 76."'He did pass away this morning' at his home in San Marcos, in northern San Diego County, said Scott M. Hanover of Thrill Entertainment Group, which managed Turner's musical career.""There was no immediate word on the cause of death.""A spokesperson for Tina Turner, who endured a tumultuous and well-chronicled marriage to Ike, tells Access Hollywood, "Tina hasnt had any contact with Ike in more than 30 years. No further comment will be made."
read more
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If you're new here, the full title is "Laid Back Loot and Transmogrification Raiding Organization." LBLTRO just doesn't work no matter how hard you try. It's a weekly drop-in gathering as people's schedules allow where we gather in a zero pressure environment to knock off some achievements, gather some transmogrification gear, and just have an all around good time.
Here are the upcoming events for the Laid Back Raid Crew. Unless otherwise stated, the raids take place between 8-10pm EST. If you're interested in attending, please contact either Repgrind (repgrind#1492) or Healblade (JackFlag#1153).


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1. Milford will be hosting Ten holiday activities will take place all day, with plenty of oppurtunities to get some holiday shopping done. Free shuttle buses will stop at each fair and the Milford Winter Farmer's Market at Town Hall. Participants can park at any location and leave their vehicle. A full list of fairs can be found here.
2. Don't miss this fabulous Christmas Craft Fair in Nashua with over 75 exhibitors displaying a variety of arts & crafts including exquisite seasonal floral arrangements, balsam wreaths, fabulous folk art & country crafts, fine jewelry, laser engraved items, fused glass, stained glass, specialty fruit & chocolates, homemade fudge, hand knits, quilts, table decor, embroidered scarves, bling clothing, NH maple syrups, handpainted metal/glass/wood decor, & lots more!!! Fabulous gifts for the holidays!!! Music of Tim Janis - Specialty Foods - Preview online at www.joycescraftshows.com (603)528-4014
3. Thinking of looking for Christmas gifts made right here in New England? The GFWC Hudson Junior Woman's Club will hold its 36th Annual Craft Fair Saturday, Dec.1 from 9 a.m. to 3 p.m, at Memorial School in Hudson. The Fair offers crafts from more than one hundred artisans from the New England Region and also features lunch and a penny raffle. From home-made candy to barbecue sauce to jewelry to themed decorated egg decorations to hand-knitted sweaters, caps, and other clothing for you, your child, your dog, or your doll, you are sure to find the perfect gift made in the USA! Admission is free. Follow the mouse signs to the fair!
4. Get a jump start on your holiday shopping. Visit the MillCity Expo Craft Fair in Manchester on Saturday, Dec. 1 from 9 a.m. to 3 p.m.This is a great place to find something unique for that special someone on your list. While your there...walk down the hall and shop in their 11,000 sq. ft. shop! MillCity Antiques. Sure to be a full day of shopping!
5. The Brookline Community Church will be holding its First Annual Brookline Christmas Faire on Friday,November 30th and Saturday, December 1st, from 5:00 to 9:00 pm each evening. This fundraiser for the church will bring the community together to celebrate Christmas while also providing an opportunity to do some Christmas shopping. The Brookline Christmas Faire will include a Silent Auction, a Talent Show,homemade dinner take-out of lasagna and macaroni & cheese, and an Angel Loft where children can shop for Christmas gifts for their family members. The Silent Auction currently includes theme baskets and gift certificates to local restaurants and businesses, with more items being added every day. There will be a door prize and refreshments. If you would like more information or would like to donate an item to the Silent Auction please contact Carol Cherian at 672-8960.


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Credits & Info
- Uploaded
- Aug 4, 2008 | 12:40 PM EDT
- Weekly Users' Choice August 6, 2008
- Daily Feature August 5, 2008
Related Stuff
If you liked this, check these out!
Author Comments
Similar to BT1, you must travel through giant bubbles, destroying enemy tanks and taking their bubbles to fuel your growth. As you grow, you constantly evolve and get ever better weapons. In the end, you'll have to face the ultimate adversary and defeat it to win the game.
This game has been in development for a long time and I'm proud to finally release it! It has FAR more content than the first game- 26 unique tank states, over 30 weapons, and over 50 enemy types! Hundreds of comments on the first game have been considered in the development of this better version!
Thanks to everyone who has supported us in this and all our games!
Note: Keyboard settings can be changed via the settings menu.
Default settings:
Up, Left, Down, and Right = A, W, S, D
Primary Fire = Hold mouse button down
Secondary Fire (when available) = Space
Pause and Menu = P
Rated 5 / 5 stars August 24, 2008
it has some annoying parts to it, but overall it is an awesone game. good job
Rated 5 / 5 stars January 27, 2009
It tortures me 2 be away from this game!
Rated 5 / 5 stars September 17, 2008
holy cow
dude. this game is awesome. i literaly cant stop playng, both sfx and gfx are flawless, idea is rich and cool and gameplay siple rocks
max score. in both rev and rating
Rated 5 / 5 stars August 31, 2008
wow. just wow.
how long did it take?
Rated 5 / 5 stars August 14, 2008
This review is useless.
...but it is without a doubt the best game ive played on here.


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Two of you — CDADave and Family Phil — have complained recently about nasty notes posted by blog trolls. My guess is that the troll my comment or blurk here. If you have trouble with a troll and have access to his/her IP address, please send it to me via private e-mail, so I can check if the clown posts here, too. Mebbe we can catch and out when of these guys.
Please keep it civil. Don't post comments that are obscene, defamatory, threatening, off-topic, an infringement of copyright or an invasion of privacy. Read our forum standards and community guidelines.
You must be logged in to post comments. Please log in here or click the comment box below for options.comments powered by Disqus


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80M : Antennas/80M
80 Meter vertical Loop is listed on dxzone.com in 1 categories, main category is Antenna for 80 meters band (antenna project for 80 meters band). Listed in our web site since Wednesday May 8 2013, received 604 total hits.
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Webmaster, add a Remote rating to your site.
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Saint-Hilaire-le-Chatel is situated in the Orne (Normandy region) in the north of France at 35 km from Alencon, the department capital. (General information: Saint-Hilaire-le-Chatel is 138 km from Paris).
Popular places to visit nearby include Belleme at 21 km and Sees at 26 km. For more places to visit and local tourist attractions see the map and listings below.
Some places that we or our contributors have visited and reviewed and can recommend close to Saint-Hilaire-le-Chatel. Note that all distances shown are 'direct' and real driving distances will be greater.
... or see ALL recommended places to visit in Orne
Hover your mouse over photos for navigation buttons
Local markets
Below we show places with official tourist classifications and other places of interest to visit nearby that should provide inspiration if you are visiting Saint-Hilaire-le-Chatel and wondering what to do next! Positions of each of these attractions is shown on the map below.
Most beautiful villages in France (see also beautiful French villages) Saint-Ceneri-le-Gerei (47km)
Recommended detour towns (fr: plus beau détour) Nogent-le-Rotrou (34km); Argentan (45km)
Regional Natural Parcs Perche (27km)
Remarkable gardens Jardin de la petite Rochelle (23km); Sassy (40km)
Sites of natural beauty Forêt de Perseigne (27km); Forêt d'Écouves (34km); Signal d'Écouves (36km); Mont du Haut-Fourché (50km)
Listed as villages d'etape - (recommended place to break a long journey) Tourouvre (10km)
Commune: Saint-Hilaire-le-Chatel
Canton: Mortagne-au-Perche
Arrondissement: Mortagne-au-Perche
Department: Orne
Region: Normandy
Postcode: 61400
from Alencon (prefecture): 35 km
from Paris: 138 km
from Calais: 282 km
from Nice: 749 km
from Bordeaux: 423 km
from Strasbourg: 531 km
Saint-Hilaire-le-Chatel is in the north of France. Most visitors arrive in one of the cross-challen ferry ports with Caen being especially close, typically within an hours drive. For driving distances to Saint-Hilaire-le-Chatel from anywhere in France see driving distances and route planner.
We have 13 other places listed nearby (within 6 kilometres of Saint-Hilaire-le-Chatel): Bazoches-sur-Hoene, Boece, Bubertre, Champs, Lignerolles, Mortagne-Au-Perche, Prepotin, Saint-Germain-de-Martigny, Saint-Langis-les-Mortagne, Saint-Ouen-de-Secherouvre, Sainte-Ceronne-les-Mortagne, Soligny-la-Trappe and Villiers-sous-Mortagne.
This page in French: Visitez Saint-Hilaire-le-Chatel
Not yet a member!? Make more of your visit with your own personal trip planner.
- Best price guarantee
- Pay on arrival


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What have the stars been up to this week?
Bad week: Sarah Jessica Parker
Bad week: Sarah Jessica Parker
Sarah Jessica Parker has admitted that she struggles with the bitchiness between women in Tinseltown. "The women that dominate culture today are pretty unfriendly towards one another. They use language that's really objectionable and cruel and not supportive" she revealed to Harper's Bazaar.
Other Galleries
» More Enterainment Photos
World Cup 2014: Latest news
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election 2014: latest
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- Congress suspends Kerala leader calling Rahul a 'joker'
- AAP to think small again: Focus on Delhi, may not contest Haryana
- Lessons from the Narendra Modi campaign
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- Cong-NCP will benefit if decision-making fast-tracked: Pawar
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A collection of things that I like and enjoy. Will include lots and lots of fandom junk, Animals, Interesting Art and funny memes and stories.
Might also include some writing if I ever get around to it.
Warning: Could display opinions.
Catching Elephant is a theme by Andy Taylor
Did you hear that, Jenny? There's a day just for us… ~V
MADAME VASTRA AND JENNY RETURN IN THE CHRISTMAS SPECIAL! yayayaya!!! So excitedddddddd.
They were amazing.
one more beautiful relationship


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Korean food craving satisfied with @jenn_mui at Seoul Garden.
So I've been on a little hiatus in posting, but not on eating.
This picture dates back to May 4th, the eve of Cinco de Mayo. Co-worker and I discussed that we should also celebrate the eve of the holiday by eating tacos for lunch. Therefore, I thought of the Mexicue truck which is parked near my office on 18th Street and 5th Ave. every Wednesdays. I've longed to go try it; however, due to the lines being long or because I always bring my lunch from home, I never had a chance to. This was the perfect excuse to ditch my leftovers and go out to the truck.
I bought one Smoked Short Rib Taco-$4 and one BBQ Brisket Slider-$3. Even though they look small, I was full with just the two items. The slider is loaded with a ton of meat, full of flavor, with just the right amount of tangy sauce. After my meal, I wished that they were parked on 18th street everyday. I want to try everything on their menu.
Mexicue Truck, www.mexicueny.com -check their twitter or facebook for weekly locations


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Top 7 Tips for Dating a Scorpio Man
Most of the Scorpio men are very intense, mysterious, sexy, deep and very brooding. They can be a little intimidating at times; but more than that, they are very intriguing. Scorpio men make for fascinating companions. They are wild, profound, exciting and a little complicated. It is wonderful to date a Scorpio man; but like every coin has two sides, it is better to get to know what you would be in for if you are dating a Scorpio man. Tips and Tricks for Dating a Scorpio Man Here are a few simple tips and tricks that you can follow while dating a Scorpio man:
- Confidence:
- Mysterious:
- One-of-a-Kind:
- Flirting:
- Straight-Forward:
- Playful:
- Loyal:


text:
From Proteopedia
|2i47, resolution 1.90Å ()
|, ,
|ADAM 17 endopeptidase, with EC number 126.96.36.199
|2a8h, 1bkc
|FirstGlance, OCA, RCSB, PDBsum
|save as pdb, mmCIF, xml
Crystal structure of catalytic domain of TACE with inhibitor
By focusing on the P1 portion of the piperidine beta-sulfone ligands we identified a motif that induces selectivity and resulted in a series of TACE inhibitors that demonstrated excellent in vitro potency against isolated TACE enzyme and excellent selectivity over MMPs 1, 2, 9, 13, and 14.
Identification of potent and selective TACE inhibitors via the S1 pocket., Condon JS, Joseph-McCarthy D, Levin JI, Lombart HG, Lovering FE, Sun L, Wang W, Xu W, Zhang Y, Bioorg Med Chem Lett. 2007 Jan 1;17(1):34-9. Epub 2006 Oct 5. PMID:17064892
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
[ADA17_HUMAN] Defects in ADAM17 are a cause of neonatal inflammatory skin and bowel disease (NISBD) [MIM:614328]. NISBD is a disorder characterized by inflammatory features with neonatal onset, involving the skin, hair, and gut. The skin lesions involve perioral and perianal erythema, psoriasiform erythroderma, with flares of erythema, scaling, and widespread pustules. Gastrointestinal symptoms include malabsorptive diarrhea that is exacerbated by intercurrent gastrointestinal infections. The hair is short or broken, and the eyelashes and eyebrows are wiry and disorganized.[1]
[ADA17_HUMAN] Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway (By similarity).[2][3]
About this Structure
2i47 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
- Condon JS, Joseph-McCarthy D, Levin JI, Lombart HG, Lovering FE, Sun L, Wang W, Xu W, Zhang Y. Identification of potent and selective TACE inhibitors via the S1 pocket. Bioorg Med Chem Lett. 2007 Jan 1;17(1):34-9. Epub 2006 Oct 5. PMID:17064892 doi:10.1016/j.bmcl.2006.10.004
- ↑ Blaydon DC, Biancheri P, Di WL, Plagnol V, Cabral RM, Brooke MA, van Heel DA, Ruschendorf F, Toynbee M, Walne A, O'Toole EA, Martin JE, Lindley K, Vulliamy T, Abrams DJ, MacDonald TT, Harper JI, Kelsell DP. Inflammatory skin and bowel disease linked to ADAM17 deletion. N Engl J Med. 2011 Oct 20;365(16):1502-8. doi: 10.1056/NEJMoa1100721. PMID:22010916 doi:10.1056/NEJMoa1100721
- ↑ Thathiah A, Blobel CP, Carson DD. Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding. J Biol Chem. 2003 Jan 31;278(5):3386-94. Epub 2002 Nov 18. PMID:12441351 doi:10.1074/jbc.M208326200
- ↑ Rabquer BJ, Amin MA, Teegala N, Shaheen MK, Tsou PS, Ruth JH, Lesch CA, Imhof BA, Koch AE. Junctional adhesion molecule-C is a soluble mediator of angiogenesis. J Immunol. 2010 Aug 1;185(3):1777-85. doi: 10.4049/jimmunol.1000556. Epub 2010, Jun 30. PMID:20592283 doi:10.4049/jimmunol.1000556


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the cats love to curl up in a ball and nap. it's hard to keep clean and free from hair.
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