text:
From Proteopedia
We present a new design for a fluorescence microspectrophotometer for use in kinetic crystallography in combination with x-ray diffraction experiments. The FLUMIX device (Fluorescence spectroscopy to monitor intermediates in x-ray crystallography) is built for 0 degrees fluorescence detection, which has several advantages in comparison to a conventional fluorometer with 90 degrees design. Due to the reduced spatial requirements and the need for only one objective, the system is highly versatile, easy to handle, and can be used for many different applications. In combination with a conventional stereomicroscope, fluorescence measurements or reaction initiation can be performed directly in a hanging drop crystallization setup. The FLUMIX device can be combined with most x-ray sources, normally without the need of a specialized mechanical support. As a biological model system, we have used H-Ras p21 with an artificially introduced photo-labile GTP precursor (caged GTP) and a covalently attached fluorophore (IANBD amide). Using the FLUMIX system, detailed information about the state of photolyzed crystals of the modified H-Ras p21 (p21(mod)) could be obtained. Measurements in combination with a synchrotron beamline showed significant fluorescence changes in p21(mod) crystals even within a few seconds of x-ray exposure at 100 K.
A newly designed microspectrofluorometer for kinetic studies on protein crystals in combination with x-ray diffraction., Klink BU, Goody RS, Scheidig AJ, Biophys J. 2006 Aug 1;91(3):981-92. Epub 2006 May 12. PMID:16698776
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
[RASH_HUMAN] Defects in HRAS are the cause of faciocutaneoskeletal syndrome (FCSS) [MIM:218040]. A rare condition characterized by prenatally increased growth, postnatal growth deficiency, mental retardation, distinctive facial appearance, cardiovascular abnormalities (typically pulmonic stenosis, hypertrophic cardiomyopathy and/or atrial tachycardia), tumor predisposition, skin and musculoskeletal abnormalities.[1][2][3][4][5][6][7] Defects in HRAS are the cause of congenital myopathy with excess of muscle spindles (CMEMS) [MIM:218040]. CMEMS is a variant of Costello syndrome.[8] Defects in HRAS may be a cause of susceptibility to Hurthle cell thyroid carcinoma (HCTC) [MIM:607464]. Hurthle cell thyroid carcinoma accounts for approximately 3% of all thyroid cancers. Although they are classified as variants of follicular neoplasms, they are more often multifocal and somewhat more aggressive and are less likely to take up iodine than are other follicular neoplasms. Note=Mutations which change positions 12, 13 or 61 activate the potential of HRAS to transform cultured cells and are implicated in a variety of human tumors. Defects in HRAS are a cause of susceptibility to bladder cancer (BLC) [MIM:109800]. A malignancy originating in tissues of the urinary bladder. It often presents with multiple tumors appearing at different times and at different sites in the bladder. Most bladder cancers are transitional cell carcinomas. They begin in cells that normally make up the inner lining of the bladder. Other types of bladder cancer include squamous cell carcinoma (cancer that begins in thin, flat cells) and adenocarcinoma (cancer that begins in cells that make and release mucus and other fluids). Bladder cancer is a complex disorder with both genetic and environmental influences. Note=Defects in HRAS are the cause of oral squamous cell carcinoma (OSCC).[9] Defects in HRAS are the cause of Schimmelpenning-Feuerstein-Mims syndrome (SFM) [MIM:163200]. A disease characterized by sebaceous nevi, often on the face, associated with variable ipsilateral abnormalities of the central nervous system, ocular anomalies, and skeletal defects. Many oral manifestations have been reported, not only including hypoplastic and malformed teeth, and mucosal papillomatosis, but also ankyloglossia, hemihyperplastic tongue, intraoral nevus, giant cell granuloma, ameloblastoma, bone cysts, follicular cysts, oligodontia, and odontodysplasia. Sebaceous nevi follow the lines of Blaschko and these can continue as linear intraoral lesions, as in mucosal papillomatosis.[10]
[RASH_HUMAN] Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.[11][12][13]
About this Structure
2ce2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
- Klink BU, Goody RS, Scheidig AJ. A newly designed microspectrofluorometer for kinetic studies on protein crystals in combination with x-ray diffraction. Biophys J. 2006 Aug 1;91(3):981-92. Epub 2006 May 12. PMID:16698776 doi:http://dx.doi.org/10.1529/biophysj.105.078931
- ↑ Aoki Y, Niihori T, Kawame H, Kurosawa K, Ohashi H, Tanaka Y, Filocamo M, Kato K, Suzuki Y, Kure S, Matsubara Y. Germline mutations in HRAS proto-oncogene cause Costello syndrome. Nat Genet. 2005 Oct;37(10):1038-40. Epub 2005 Sep 18. PMID:16170316 doi:ng1641
- ↑ Gripp KW, Lin AE, Stabley DL, Nicholson L, Scott CI Jr, Doyle D, Aoki Y, Matsubara Y, Zackai EH, Lapunzina P, Gonzalez-Meneses A, Holbrook J, Agresta CA, Gonzalez IL, Sol-Church K. HRAS mutation analysis in Costello syndrome: genotype and phenotype correlation. Am J Med Genet A. 2006 Jan 1;140(1):1-7. PMID:16329078 doi:10.1002/ajmg.a.31047
- ↑ Kerr B, Delrue MA, Sigaudy S, Perveen R, Marche M, Burgelin I, Stef M, Tang B, Eden OB, O'Sullivan J, De Sandre-Giovannoli A, Reardon W, Brewer C, Bennett C, Quarell O, M'Cann E, Donnai D, Stewart F, Hennekam R, Cave H, Verloes A, Philip N, Lacombe D, Levy N, Arveiler B, Black G. Genotype-phenotype correlation in Costello syndrome: HRAS mutation analysis in 43 cases. J Med Genet. 2006 May;43(5):401-5. Epub 2006 Jan 27. PMID:16443854 doi:jmg.2005.040352
- ↑ Zampino G, Pantaleoni F, Carta C, Cobellis G, Vasta I, Neri C, Pogna EA, De Feo E, Delogu A, Sarkozy A, Atzeri F, Selicorni A, Rauen KA, Cytrynbaum CS, Weksberg R, Dallapiccola B, Ballabio A, Gelb BD, Neri G, Tartaglia M. Diversity, parental germline origin, and phenotypic spectrum of de novo HRAS missense changes in Costello syndrome. Hum Mutat. 2007 Mar;28(3):265-72. PMID:17054105 doi:10.1002/humu.20431
- ↑ Gripp KW, Innes AM, Axelrad ME, Gillan TL, Parboosingh JS, Davies C, Leonard NJ, Lapointe M, Doyle D, Catalano S, Nicholson L, Stabley DL, Sol-Church K. Costello syndrome associated with novel germline HRAS mutations: an attenuated phenotype? Am J Med Genet A. 2008 Mar 15;146A(6):683-90. PMID:18247425 doi:10.1002/ajmg.a.32227
- ↑ Lo IF, Brewer C, Shannon N, Shorto J, Tang B, Black G, Soo MT, Ng DK, Lam ST, Kerr B. Severe neonatal manifestations of Costello syndrome. J Med Genet. 2008 Mar;45(3):167-71. Epub 2007 Nov 26. PMID:18039947 doi:10.1136/jmg.2007.054411
- ↑ Gremer L, De Luca A, Merbitz-Zahradnik T, Dallapiccola B, Morlot S, Tartaglia M, Kutsche K, Ahmadian MR, Rosenberger G. Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation. Hum Mol Genet. 2010 Mar 1;19(5):790-802. doi: 10.1093/hmg/ddp548. Epub 2009 Dec, 8. PMID:19995790 doi:10.1093/hmg/ddp548
- ↑ van der Burgt I, Kupsky W, Stassou S, Nadroo A, Barroso C, Diem A, Kratz CP, Dvorsky R, Ahmadian MR, Zenker M. Myopathy caused by HRAS germline mutations: implications for disturbed myogenic differentiation in the presence of constitutive HRas activation. J Med Genet. 2007 Jul;44(7):459-62. Epub 2007 Apr 5. PMID:17412879 doi:jmg.2007.049270
- ↑ Sakai E, Rikimaru K, Ueda M, Matsumoto Y, Ishii N, Enomoto S, Yamamoto H, Tsuchida N. The p53 tumor-suppressor gene and ras oncogene mutations in oral squamous-cell carcinoma. Int J Cancer. 1992 Dec 2;52(6):867-72. PMID:1459726
- ↑ Groesser L, Herschberger E, Ruetten A, Ruivenkamp C, Lopriore E, Zutt M, Langmann T, Singer S, Klingseisen L, Schneider-Brachert W, Toll A, Real FX, Landthaler M, Hafner C. Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome. Nat Genet. 2012 Jun 10;44(7):783-7. doi: 10.1038/ng.2316. PMID:22683711 doi:10.1038/ng.2316
- ↑ Guil S, de La Iglesia N, Fernandez-Larrea J, Cifuentes D, Ferrer JC, Guinovart JJ, Bach-Elias M. Alternative splicing of the human proto-oncogene c-H-ras renders a new Ras family protein that trafficks to cytoplasm and nucleus. Cancer Res. 2003 Sep 1;63(17):5178-87. PMID:14500341
- ↑ Lander HM, Hajjar DP, Hempstead BL, Mirza UA, Chait BT, Campbell S, Quilliam LA. A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. J Biol Chem. 1997 Feb 14;272(7):4323-6. PMID:9020151
- ↑ Williams JG, Pappu K, Campbell SL. Structural and biochemical studies of p21Ras S-nitrosylation and nitric oxide-mediated guanine nucleotide exchange. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6376-81. Epub 2003 May 9. PMID:12740440 doi:10.1073/pnas.1037299100


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Tag: AppleTrivia
TUAW TV Live: The Unofficial Apple Trivia episode (Updated)
Today on TUAW TV Live, I'll be running a bit of a trivia contest -- or at least testing your abilities at performing internet searches. It's sure to be a fun and educational episode for anyone who loves Apple. Below, you'll find a Ustream livestream viewer and a chat tool. The chat tool...
TUAW TV Live at 5 PM EDT: Test your knowledge of Apple trivia
The last week has given Apple fans a chance to reminisce about the company, its products, and the individuals who have helped make history. Now it's your chance to show just how much you know about Apple. Today on TUAW TV Live at 5 PM EDT, I'll have a pile of Apple trivia questions ranging in...
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subset: commoncrawl


text:
Definition of tsuris in English:
tsurisLine breaks: tsuris
Pronunciation: /ˈtsʊrɪs /
(also tsores /ˈtsɒrəs/)
noun[mass noun] North American informal
Problems or difficulties; trouble: the NBA has its share of tsuris these days
More example sentences
- When you have my tsuris [troubles], you'll talk differently.
- All this tsuris so I can watch 'Curb Your Enthusiasm.'
- Everyone got the drive-by descriptions; when she made a phone call, everyone heard the tales of woe and tsuris.
early 20th century: Yiddish, plural of tsore 'trouble, woe', from Hebrew ṣārāh.
Definition of tsuris in:
- The US English dictionary
Get more from Oxford Dictionaries
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Word of the day anomalous
Pronunciation: əˈnɒm(ə)ləs
deviating from what is standard, normal, or expected


text:
KONY 2012 co-founder JASON RUSSELL has been detained for allegedly being drunk and lewd in public!
Well, there goes many of their supporters! Wonder what his son thinks of that?
Jason Russell, the filmmaker behind the Invisible Children viral video, was allegedly detained in San Diego after being found wearing only his underwear while masturbating and vandalizing cars Thursday Morning. Russell's video, which has gained the support of celebrities such as Rihanna, Justin Bieber, P.Diddy, Kim Kardashian and Oprah, aimed to make Ugandan warlord Joseph Kony and his wicked ways of abducting thousands of children for years more well known in America so the administration would finally eradicate him.
BRITNEY SPEARS' dad, Jamie Spears, plans to end his conservatorship as a wedding gift to his daughter.
Oh, yep. We get it. From one master to another.
Still, Jamie Spears feels his once cuckoo kid has finally regained control of her senses, so he's planning to rescind control of her finances and place them in her hands when she finally says "I do" to fiance Jason Trawick in the very near future (sources say Valentine's Day on Maui). Which basically means that Britney's set to get her life back when she gets married…only, wait…that life will essentially be in Jason Trawick's hands…
CHARLIE SHEEN is telling everybody he's not crazy anymore. O-kaaaaaay. Let's give your words the benefit of the doubt, Charlie, then we'll decide.
The former "Two And A Half Men" star talked to the media at the FOX Television Critics Association party in Pasadena, California and told them he should now be regarded as a more lucid individual after having recovered from his seriously skewed meltdown in the last year and a half. Maybe he's trying to convince everybody he's now ready to get down to some serious work and regain his status as an A-list celebrity…
A usually tight-lipped BRITNEY SPEARS has opened up about her ongoing struggle with weight which began shortly after the birth of her two sons, Sean Preston and Jayden James. Is Britney still addicted to Cheetos?
The recovering star, who's vacated the train wreck job that Lindsay Lohan now holds, seems to be thriving under the conservatorship held by her father, Jamie Spears. And she's even found love in the person of her former agent, Jason Trawick. She's happier and regaining the ground she lost a few years ago, but her troubles with weight gain remain…
CHRIS BROWN is not above throwing a tantrum on Twitter if his five million plus followers continue to bombard him with RIHANNA comments, pissing him off so much, he's deleted his account.
Okay, so it's not exactly like punching his fist through a glass window like he did at "Good Morning America," but man, what a waste of Twitter timeline!
JENNIFER LOPEZ suddenly broke down and cried onstage while singing about lost love during her performance at the the Mohegan Sun Arena's 15th anniversary celebration a few hours ago. Did she just let go of all her repressed emotions from her separation from Marc Anthony? Or were those tears of happiness from finding love again with Bradley Cooper?
Jenny from the block was gasping with tears during her rendition of "If You Had My Love," a song she told the audience was:


text:
I found measing tool does't stop by double click. It is annoying bug.
Double click works. I'm guessing it just has a very low tolerance making most double clicks not register
- Jackie
1) Which version of IE do you use?
2) If IE 9: Are you running IE in Compatibility mode?
3) What is the language of your operating system (OS)?
Things I've noticed:
- Double click works fine in IE 9 (without Compatibility mode), Firefox, Chrome and Safari.
- It doesn't work on IE 7 and IE 8.
- In IE 9 it doesn't work if you have enabled the Compatibility mode.
Also I've noticed that some functions doesn't work proper on a non-English OS.
However (as a workaround) 'SHIFT + left mouse click' works with all browsers (even IE 6).
System: MapGuide Open Source 2.4 as well as AIMS 2013 with Apache on Windows Server 2012 (German OS)
- Bernhard
Yes, it works without compatibility mode. Thank you for the information.


text:
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Predator Hunts My Love
Hell alchohol alone ruins people's judgement, and so many people drink. It's not a stretch to think they'd get drunk, say screw it and buy 100 bucks worth of meth then go on a binge. Booze (I've seen first hand) turns normal law abiding people into criminals...........engaging in behavior they DEFINITELY wouldn't even consider when they were sober.
A store selling drugs + booze? That's messed up.
Predator Hunts My Love
And I realize it boils down to decision making, but I still think there would be far too many negative effects on society if hard drugs were legalized. Actually not just hard drugs, I don't think kids should be toking up. As it stands it looks like 90% of high school kids are full blown potheads.......and it's no wonder why this country is near the bottom in terms of educating youth.
Kids neglecting their studies, instead lighting up and playing video games when they get out of school.
Predator Hunts My Love
are you a badfish too?
pot is illegal, its controlled heavily in the states i grew up in, yet it was much easier to come by than alcohol
no one wants KIDS doing drugs, just like they dont want kids drinking... legal doesnt mean full tilt, surely there will be age restrictions
the vast majority of people in jail for drug charges are more for trafficking or distributing, not 'using'
and the majority of the major SE/OD of drugs come from inconsistent formulas and numerous cutting agents
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Why would we want to add thousands of teenage of heroin addicts and crack adddicts to the thousands of teenage alchoholics we have now?
I would support legalization of pot, but I wouldn't want to see the guy on the corner pan handling a few bucks to buy some crystal meth instead of a bottle of booze.
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Predator Hunts My Love
Kid sitting in class doing rails on his desk, etc. It's just ridiculous.
But are you really sure about the statement in bold? I mean you can overdose due to toxicity from drugs themselves.
You do too much cocaine, you risk SCDS. And doctors still don't even know why the heart shuts down.
are you a badfish too?
and as far as drugs, its safe to say i have sufficient knowledge
Predator Hunts My Love
As far as most people being in jail for drug charges I also disagree.
Many people fail drug screens while they're on probation/parole and are sent back for a violation of their parole/probation.
And I'm not chosing a side on that issue I'm just stating the law is the law and nothing changes that. But children still shouldn't have an easier road in finding dope.
|affect, america?, drug, legalisation, south
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An ideal salt grinder, easy to use and refill and matches the pepper mill purchased recently. One of the things I like best, it is so easy to select the size of salt (or pepper) that is wanted. Have already recommended the item to others.
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Excellent product! Easy to use and looks good on the table, too! Easy to operate it stores with the mill uppermost so does not leave grains of salt on the work surface. It grinds well from fine to coarse grains.
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Excellent service in our local Dunelm branch. As always it is a pleasure to shop there.
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I have tried numerous salt and pepper grinders over the years, however, they all disappointed in one way or another. I decided to give this one a try. I am glad I did as this grinder is very good! The 'upside down idea' is fantastic, and the grinder is very easy to use, including refilling and adjusting the level of coarseness. Most importantly for me, the grinding mechanism is very smooth and, depending on your choice, it grinds both salt and pepper from coarse to very fine. I am very happy with my purchase and I would highly recommend these OXO grinders.
Service and delivery comments:
The product is good, but I was disappointed with the service and delivery, which took longer than expected. I had the product delivered to my local store. However, my local store did not contact me to inform me about the product's delivery. In fact, I had to contact the store myself to enquire.
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LUBBOCK, TX (KCBD) - The District 83 race has become a heated one over the past few weeks. Incumbent Delwin Jones is 1 of 3 long time State House Representatives whose political career is on the line this week. After some negative campaigning, former District 84 Representative, Carl Isett, spoke up about the race for the first time.
The run-off election started heating up when former District 83 candidate Zach Brady endorsed Delwin Jones after the State Ethics Commission investigated Perry's campaign. Then, Perry announced if elected he wants to repeal House Bill 1403, which he says gives $33-million in state tuition scholarships to illegal immigrants.
"I challenged his voting record and if there's anything we should engage our legislation by is their voting record and it got personal to him because obviously it doesn't support the values of this district," said Perry.
After this comment, Jones put out a radio ad stating Perry owes him and former District 84 Representative Carl Isett an apology because he supported the same bill. "Well I think he owes Carl because if I was terrible wrong in it then Carl was, and Carl was not wrong. I was not wrong. So he should apologize to me for saying that I did it when I didn't do it, and Rob Duncan did it. Carl Isett did it. 150 or so other legislatures did it," said Jones.
Isett says he does not want to endorse one candidate or the other, "I had every intention, I was just trying to stay out of this race."
However, Isett disagreed with the radio ad. "Delwin asked or suggested in a radio ad that Charles Perry owes me an apology or should apologize to me for his position. I don't agree with that. I don't think he owes me an apology. He's challenging an action that the legislature took and he has every right to do that," said Isett. Both candidates say they're disappointed with the negative turns the campaign has taken, but don't plan to slow their efforts in the final days.
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The 1st Televised Kennedy/Nixon Debate
On September 26, 1960 Democratic candidate Senator John F. Kennedy and Republican candidate Vice President Richard Nixon participated in the first of four televised debates. Americans for the first time could tune in and watch presidential debates on television, or listen on the radio.
About 70 million people tuned in for the Kennedy/Nixon debates. When they turned on their television sets, they were actually able to see Richard Nixon and John Kennedy. Nixon had refused makeup for the cameras, and hadn't gained back his natural weight after a serious knee injury and two weeks in the hospital. Kennedy, on the other hand, had been campaigning in southern California and appeared on camera with a healthy tan.
The story has it that those Americans who tuned in over the radio believed the two candidates were evenly matched, but tended to think Nixon had won the debates. But those 70 million who watched the candidates on the television believed Kennedy was the clear victor.
While there aren't any qualified statistics to back up this claim, what is certain is that Kennedy took a leap in the polls after the debate. Appearances, it seemed, suddenly mattered in Presidential races, far more than they ever had before. Kennedy himself said after the election that "it was TV more than anything else that turned the tide" toward his victory.
It's curious to think who might have been elected if modern technology had been around throughout U.S. history. Washington wore dentures. Lincoln had a high-pitched voice. William Howard Taft weighed over 300 pounds. James Madison was 5′ 4″.
-from The National Archives' Prologue: Pieces of History
What pre-television President would you most like to see speak?
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Specialty Services
McLean-Arlington Medical Associates is committed to providing patients with outstanding medical care. We believe that providing high-quality care is not only about the medical advice that we dispense, but more importantly about the relationships we have with our patients. We know that a positive, trusting relationship with your physician is essential to keeping you healthy. That is why our expert physicians and responsive staff will help you with all your primary care needs, including but not limited to:
- General physical health
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- Immunizations and flu shots
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We continue to strive to be a leader in innovative medical practices and the following ancillary services are available within our office:
- On-site comprehensive laboratory testing open daily, Monday - Friday
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Our board certified physicians and friendly staff look forward to serving all your healthcare needs. In order to facilitate your visit with us, please make note of the following for your first visit:
- We focus on the medical needs of adults, age 18 or older.
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- We accept many insurance plans. Please be sure to bring your health insurance card with you.
- Provide your physician with a current medication list and note any allergies.
- Any medical records related to your healthcare treatment.
McLean-Arlington Medical Associates is committed to enhancing the quality of health care outcomes and enrich the process of individualized care for our patients in a continuous and comprehensive manner.
To schedule an appointment or for more information, please contact us at 703-992-0649.


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I have made this recipe many times over the years and everyone loves it! Yum!
Baked Brie with Golden Raisin Compote
Photo: Howard L. Puckett; Styling: Lydia Degaris-Pursell
Category Finalist: Starters and Drinks. "This flavorful appetizer is great because most of the prep work can take place before guests arrive. The Brie is rich enough to carry the appetizer with a tart and sweet compote. To ease slicing, keep Brie chilled until ready to use." --Elizabeth Bennett, Mill Creek, WA
Yield: 20 servings (serving size: 2 topped baguette slices)
More From Cooking Light
Nutritional Information
Amount per serving
- Calories: 132
- Calories from fat: 22%
- Fat: 3.2g
- Saturated fat: 2g
- Monounsaturated fat: 0.9g
- Polyunsaturated fat: 0.1g
- Protein: 3.7g
- Carbohydrate: 23g
- Fiber: 1.1g
- Cholesterol: 11mg
- Iron: 0.7mg
- Sodium: 178mg
- Calcium: 31mg
- 6 cups chopped peeled Granny Smith apple (about 1 1/2 pounds)
- 1 cup vertically sliced red onion (1 small)
- 1 cup golden raisins
- 1/3 cup white wine vinegar
- 1/4 cup granulated sugar
- 1/4 cup packed brown sugar
- 1/2 teaspoon ground cinnamon
- 1/2 teaspoon ground cardamom
- 1/4 teaspoon salt
- 1/4 teaspoon ground ginger
- 1/4 teaspoon ground nutmeg
- 8 ounces Brie cheese, thinly sliced
- 40 (1/4-inch-thick) slices French bread baguette (about 8 ounces)
- Thyme sprigs (optional)
- Combine first 11 ingredients in a large saucepan; bring to a boil. Cover, reduce heat, and simmer 30 minutes, stirring occasionally. Uncover and cook for 5 minutes or until slightly thick, stirring occasionally. Cool.
- Preheat oven to 400°.
- Divide Brie slices into 40 even pieces. Spread 1 1/2 tablespoons compote over each baguette slice; top each with 1 piece of cheese. Arrange the slices on a large baking sheet. Bake at 400° for 5 minutes or until cheese melts. Garnish with thyme sprigs, if desired.
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Baked Brie with Golden Raisin Compote Recipe at a Glance
- COURSE: Hors d'Oeuvres
- CONVENIENCE: Entertaining
- CUISINE: American
- MAIN INGREDIENT: Cheese, Fruits
- DIETARY CONSIDERATION: Low Cholesterol
- COOKING METHOD: Bake
- OCCASION: Autumn, Spring, Summer, Winter
- PUBLICATION: Cooking Light
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Categories > TV > Degrassi > Secrets We Keep
No Talking Him Out of This One0 Reviews
Brianna's POV Adam's mind is set, now it's just up to his friends to decide if they've got his back.
"You punch like a girl, Eli," I joke, glancing over at him.
"Well, you are highly fragile. I wouldn't want to break you," responds Eli, his adorable smirk set on his lips.
In the beginning I wasn't positive about my decision to date Eli behind Claire's back, but it's not entirely bad. He had driven me home last night and staid over for almost two hours. Mainly we talked; acted like idiots, much to my brother's displeasure, and Eli helped me with math...it was normal.
"How did you do on your exams?" Eli asks Adam.
Instead of answering Adam continues to scan the hallway. What in the world is he doing now, giving Eli the silent treatment...how mature of him.
"Waiting for someone?" Eli questions, trying once again to reach the now statue still Adam.
"Yeah," responds Adam bluntly, "Fitz."
"And how is Fitzy boy?" I inquire. "Still your super awesome bff?" I continue using an overly excited voice, sounding nothing like myself.
When Adam does not respond I look around, there standing in the middle of the hall is Fitz. Upon seeing him Adam balls his hand into a fist, beginning towards the bully.
"Adam, what are you doing," Eli questions taking a step towards him. I can tell Eli is genuinely concerned for his friend.
"You were right, Eli," says Adam, continuing on toward Fitz.
I watch in horror as Adam punches Fitz in the stomach, hard enough that he falls to the linoleum floor. Adam has no idea what he is getting himself into. As he goes to assault Fitz again Eli and I grab Adam by the arms, holding him back.
"Let's go, Rocky," Eli says, "before a teacher comes."
"You better say your prayers, freak! I'm going to fight your ass after school!" hollers Fitz, still crumpled up on the floor.
"Do it!" shouts Adam, fighting against our hold on him.
"Adam, let's just go. He's not worth it," I say in a low voice, trying to talk some reason into him.
With one final tug Adam pulls free from Eli and my grasp, "I fight my own battles."
Eli makes to go after him but I stop him, placing my hand on his chest. Going after Adam will only make things worse between everyone, "Just let him go, Eli."
His eyes boar into mine, causing me to lose my train of thought for a moment, "Wait for Claire. I'm going to find Adam before he does something stupid." Eli says.
"And how am I supposed to know where you are?" I question, not ecstatic about Eli not letting Adam be.
"I'll send you a message," he replies, patting the pocket in which his cell phone is in.
"Fine, just go," I answer, trying not to be too sharp with him.
There are certain times when I allow my temper to get the best of me. This of course is something I have worked on for years now but Eli drives me insane sometimes. As I take a deep breath in, trying to calm myself I spot Claire.
"Claire! Claire!" I call waving at the only girl I've ever actually been able to be around for longer than five seconds.
"Oh, hey, Brianna," she says coming to stand next to me. "Where's Eli?"
"In the weight room with Adam, come on, he wants us to meet him." I explain, heading down the hall.
"What's going on?" asks Claire, a confused look etched on her brow.
"Just come on, Claire," I repeat, growing slightly impatient.
Together we quickly make our way to the weight room. Once I have rounded the corner I can see Eli standing in the doorway.
"Claire...Brianna, I was beginning to think something happened," Eli says with a smirk.
God how I love his smirk...the way it makes my heart beat a little bit faster every time it plays across his gorgeous lips. Caught up in his facial features I reply to Eli's comment without thinking, "What'd you think we died or something?"
Eli sets his gaze on me, a hurt look in his majestic hunter green eyes.
"Sorry, Eli, "I apologize, running my finger over his hand. Claire, focuses on Adam, doesn't notice a thing.
How could I possibly be so stupid? I know Eli still feels guilty about his ex - girlfriend's death and yet there I go bringing up people dying.
"Called in re - enforcements, huh?" asks Adam, turning his attention from the hanging punching bag to the three of us.
"Thought I might need some help talking you out of certain doom," replies Eli, taking a step towards Adam.
"What am I supposed to do, Eli?" questions Adam. "I hate Fitz. I want to make him hurt."
Claire takes in a deep breath, letting it out slowly, "Gandhi said an eye for an eye makes the whole world blind."
"Well Gandhi never met Fitz," remarks Adam.
I clap my hands over my mouth, trying to hide the fact I am snickering. Adam is right though, Fitz can't be taken down by kindness; you had to outsmart him or use physical force.
"I think you're missing the point, Rocky," says Eli looking my way for back up.
Knowing there is no way to talk Adam out of fighting Fitz I decided to support him, ignoring Eli's gaze. "Look Adam, fighting Fitz won't hurt him, it'll only give you a black eye and a bloody nose, but I support you. If you're going to fight I'll be standing there right next to you."
Adam smiles at me, "Thanks, Bri," he says before turning his attention to Eli and Claire both who are eyeing me with looks of shock, "The point is when someone disses me I fight back."
"Even if that means you get hurt?" questions Claire.
Without answering Adam pushes past her, disappearing in the crowd of people that now flood the halls. All of us stand in an uncomfortable silence, no one willing to speak.
"We have to stop him," Eli says after a few minutes.
"Thank you captain obvious," I remark, rolling my eyes.
"Yeah...how?" questions Claire, ignoring my comment.
Eli stands still for a few seconds before shrugging...he has no ideas.
"What? For once you don't have a sneaky plan?" says Claire meaning it as a joke.
Obviously not finding Claire's words the least bit humorous Eli frowns exiting the weight room he eyes Claire with a look of utter disappointment. I follow behind him, leaving Claire to stand alone.
"You know I'm right Eli. Adam is going to fight Fitz no matter what we say, we might as well be there to help him," I say, placing a hand on Eli's leather covered shoulder.
The dark haired boy turns on his heel, eyes locking with mine, "Bri, do you remember what Fitz did to you? He'll do the same thing to Adam."
"I don't think Fitz will put Adam in intensive care for three days because he broke up with him," I state, not about to give up.
"If you think we should help Adam fight Fitz then I'll be there. But don't expect me to be happy about it," Eli says.
"Thank you," I reply, kissing him on the cheek before hurrying off to class


text:
San Francisco electronic producer Paul Salva
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This was my first recipe from the Essential Dinner Tonight cookbook, even though I had already tore it out of the original magazine. Overall, an A rating....but the crepes just completely disintegrated on impact. In the photo we noticed that at least 4 crepes were used... Now we know why. My 15 year old went for seconds and that's why I consider this a hit. I would have liked a thicker sauce and will experiment with reducing the chicken broth a little more or adding a little Dijon mustard.
Creamy Chicken and Mushroom Crepes
BayGourmet Posted: 10/16/11
MelMcC Posted: 02/26/12
I'm sad this doesn't have more and better reviews, I love this dish. I gave up on the crepes after the first time, they're not worth the trouble and they do fall apart. But the rest is fantastic - creamy, savory, full of flavour. I serve it over rice - usually the easy frozen brown or red blend from Trader Joe's. For special occasions I always make canapés with smoked salmon and dill creme fraiche, so this is a standby in our house to use up the extra creme fraiche. I serve it for company all the time and always get requests for the recipe.
Reuscher2010 Posted: 11/17/12
I agree with the previous user in that I am surprised there aren't more reviews for this recipe! My husband and I enjoyed these. Couldn't find creme fraiche (and didn't feel like making it) so I used heavy cream instead. Very flavorful and easy to prepare. Will definitely make again.


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Please send any motions you have related to social work and social justice for the SWAN Conference 2014 Annual General Meeting (Saturday morning of the conference) to:
wheresjane [at] gmail.com
Please send by Thursday 10th April.
There will also be an opportunity for regional meetings at this year's conference.
We are delighted to announce that the documents for this year's SWAN Conference in Durham are now available. Please download these files at the foot of this article.
Read more...
SWAN North East have extended their deadline for proposals for papers, workshops and presentations for this year's national SWAN conference. Please download the full call for papers at the link below. Please send proposals to https://www.dur.ac.uk/conference.booking/details/?id=259
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Found November 24, 2012 on Celtics Town:
PLAYERS: Thabo Sefolosha, Jason Terry, Brandon Bass, Kevin Durant, Serge Ibaka, Jeff Green, Kendrick Perkins
TEAMS: Boston Celtics, Oklahoma City Thunder
TEAMS: Boston Celtics, Oklahoma City Thunder
You've seen the internet meme: 1. Step one. 2. Step two. 3. ???? 4. PROFIT!!! Well, I'm happy to report that the Celtics discovered the variable represented by the ????. Pay close attention.Step 1: Establish a comfortable lead with plenty of time to blow it (or "Set the table").It all began with this play.The Celtics had kept pace with the Thunder for most of the game, even outplaying them slightly. The defense was clicking (for once), and it was clicking against a talented, explosive offense, no less. What's more, with a big run at the end of the third quarter, Boston had actually pushed its lead to double digits. So when Thabo Sefolosha (who got soundly beaten in the final quarter) helped too much on Jason Terry, Terry kicked to Pierce for the open three and the Celtics were rolling.Step 2: Fail to finish off opponent (or "Hint at the collapse").Boston played this step perfectly. After Pierce pushed the lead to 14 with his 3-pointer, the Celtics stayed ahead…but they didn't extend...
Original Story: http://www.celticstown.com/2012/11/24...
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Graham Greene
Adult Fiction GREENE
Summary: "I met Aunt Augusta for the first time at my mother's funeral..." nbsp; Described by Graham Greene as "the only book I have written just for the fun of it," Travels with My Aunt is the story of Hanry Pulling, a retired and complacent bank manager who meets his septuagenarian Aunt Augusta for the first time at what he supposes to be his mother's funeral. She soon persuades Henry to abandon his dull suburban existence to travel her way#151;winding through Brighton, Paris, Istanbul, and Paraguay. Through Aunt Augusta, one of Greene's greatest comic creations, Henry joins a shiftless, twilight society; mixes with hippies, war criminals, and CIA men; smokes pot; and breaks all currency regulations. nbsp; Originally published in 1970, Travels with My Aunt offers intoxicating entertainment, yet also confronts some of the most perplexing human dilemmas. This Penguin Deluxe Edition features an introduction by Gloria Emerson.
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Henry Pulling
Age: Middle aged
Staid; inexperienced; dahlia expert.
Bank manager
Age: 70s
Henry's aunt; bohemian; world-traveler.


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A 31-year-old man died in a dirt bike crash at a Jordan River state park for off-road vehicles Saturday, police said.
Brian Buttars of Lehi was going over a double jump on a motocross track when he crashed his dirt bike about 12:30 p.m., said Salt Lake County Sheriff's Lt. Don Hutson. He was wearing full protective gear, but suffered traumatic injuries and went into cardiac arrest. Buttars was pronounced dead at the park, which is located at 2800 N. Rose Park Lane (1935 West).
The bike was found at the bottom of the second of the two jumps. Deputies are investigating what caused him to crash.
"It was not witnessed by anyone," Hutson said. "There were other people at the park, but no one in that immediate area."
Buttars was at the park with friends, riding on one of the more advanced of four dirt tracks, said Bob Rosel, a park manager with the Utah Department of Natural Resources. There was also a fatal accident at the park in 2002.
After they heard about the crash, two other riders, 26-year-old Craig Thomas, of Bluffdale, and 28-year-old Paul Hansen, of Herriman, decided to leave the park for the day.
"When you find out someone died, as a rider, he would have wanted you to keep riding. That's what I would want," Thomas said. "In a second sense, you want to have respect for his family."
"I hate to see this happen, but it's kind of part of the game. There's always that risk," Hansen said.


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About Us
As a proud Australian family-owned winery, our story so far has its fair share of tradition. Sarantos and Constantina Moularadellis emmigrated from Greece separately and met while picking vines in Australia's Riverland region. They soon were married and had children.
And so back in the 1950's, began an Australian wine dynasty lead by Sarantos and Constantina Moularadellis, where family means everything. And for the family that means we never stop striving, learning, pioneering, and aiming to consistently produce the best quality wines for Australians and the wine loving world.
Being a family winery, passion runs through our veins and hard work is given, as we continually strive to nurture our traditions and uphold our reputation for quality and continued improvement, which goes back to the 1960's, when we were first recognised for growing quality fruit.
The offical birth of Kingston Estate was in 1985 when eldest son Bill gained his Oenology degree and we crushed our first commercial vintage. Soon after we started to export our wines and select growers to supply additional premium fruit for further improvement.
Bill's foresight, innate ability to innovate and his strength of character has continued to drive Kingston Estate Wines to produce better and better wines each and every vintage. We continue to expand our fruit sourcing horizons to include cooler climate South Australian regions and to focus on varietal blend options and style development. Every Kingston Estate wine we make must reflect South Australian's best regional qualities.
While the roots of Kingston Estate's family history run very deep in South Australia's Riverland region, we apply our unique family passion to ensure every Kingston Estate wine we produce reflects South Australian's best regional qualities.
That means we strive to secure long-term fruit supply contracts from South Australia's premium grape growing regions to ensure we can achieve those wonderful regional flavours and styles.
Our Echelon range of wines showcases the pinnacle of our wine making from each vintage. Winemaker Bill Moularadellis aims high to make the best possible wines the family's skills and fruit deserve. So he chooses only the finest parcels from each vintage - fruit that displays exceptional vibrancy and intensity of flavour to craft Echelon wines.
For our Kingston Estate range of wines, for each vintage we source fruit from the two South Australian wine regions that best display the true essence of each varietal. Then we apply our unending passion and generations of winemaking knowledge to produce the generously flavoured wines that Kingston Estate Wines have become renowned for.
In the late 1990's with his unending family pioneering spirit, Bill Moularadellis looked to the future, planting new varieties suited to the Riverland's warm climate including Merlot (now hugely popular in Australia), and planting Australia's largest single planting of Petit Verdot.
Bill's foresight and resolve, when many in the wine industry doubted his vision, was rewarded when Petit Verdot emerged as the 'next big thing' and his 2002 Kingston Echelon Petit Verdot was awarded top gold at the 2003 Royal Melbourne Show.
The awards and accolades continue as the 2008 Kingston Estate Petit Verdot struck Gold at the 2009 San Francisco International Wine Show and Silver at the 2009 Decanter World Wine Awards.
Originating from Europe, this variety's name means "little green one", highlighting its need for the warmer climate to ripen it to perfection. The Riverlands warm Mediterranean climate is gaining a reputation as the signature growing region for Australian Petit Verdot.


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by Nick Beres
MURFREESBORO, Tenn. - A woman, who admitted to shooting and killing a dog, has been charged with a class E-Felony. It's now a rare animal harm case that's actually headed to court.
The question: Was the shooting of a neighbor's dog justified?
There's a growing issue of whether a key witness in the case has been threatened not to testify.
Carolyn Layne said she would let her hound, Tinker roam her 50 acre Rutherford County horse farm before dinner, but one night, he didn't come home. That's when a friend knocked on her door.
"I said 'where's my dog? Is he dead?' And he said 'yes,'" said Layne.
It turns out one of Layne's neighbors, Jacklyn Everson, shot the dog.
"I was just doing what I thought was right," said Everson.
She said Tinker had strayed onto her property and was growling and snapping at her. She felt she had no choice but to shoot the dog to protect her and her family.
Rutherford County Sheriff's Deputies investigated and arrested Everson for Intentional Killing of an Animal, a class E-Felony.
Layne said she wants to push the case to court. Everson said she's ready.
"I'm going to represent myself and make them look like an idiot. She can't have her dogs terrorizing people," said Everson.
A witness, who asked not to be identified, was there the day of the shooting. She's been subpoenaed to testify against Everson and said the dog was not aggressive.
In a twist, that witness has now filed a report with the Murfreesboro Police Department, claiming that Everson and her boyfriend have threatened her. She claimed they told her if she testifies "she will get what's coming to her," and that she needed to "watch her back."
Everson strongly denied making any threats.
"We take allegations of threats very seriously," said Kyle Evans, with the Murfreesboro Police Department.
Evans said police will not tolerate intimidation of witnesses.
Everson is cooperating and so is Layne, who believes her dog was needlessly killed.
"Tinker was my baby," said Layne.
Murfreesboro Police are still investigating the threat allegations, but no additional charges have been filed.
The criminal case for shooting the dog goes to trial at the end of April.
Email: firstname.lastname@example.com
Facebook: Facebook.com/NC5NickBeres
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