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Benefits of Exercise for Individuals Living with HIVBy · Comments
July has been officially declared the 1st National HIV Awareness Month. What a great opportunity to welcome my first guest blogger by sharing an article written by Jim Rollince of Gym Source on the therapeutic effects of light to moderate exercise in patients with HIV.
Benefits of Exercise for Individuals Living with HIV
I am so grateful to my family for holding down the fort while I attended the 2012 Fitness and Health Bloggers Conference. I met some exceptional health, fitness and wellness professionals, both speakers and attendees. I will be blogging about the new evidence-based information I learned in the coming weeks. Speakers presented the latest research on weight loss and weight management, fitness, wellness, complementary and alternative medicine (CAM), and nutrition.
Pre-Conference – Focusing on my Breath
It's Stress Management Month – Try MeditationBy · Comments
Since April is stress management month, I thought I'd share an excerpt from my FREE Stress Management Guide. If you'd like to read the full guide, simply sign up on my blog: positivelywell.com and you'll receive it by e-mail.
Meditation is one of the easiest, healthiest, most misunderstood habits. The reality is meditation is the focus of many research studies, and the positive effects on one's health are encouraging. Here are some common concerns with mediation, and my thoughts on how to work through them:
Can't sit still?
What's in your courage cocktail?By · Comments
The opposite of courage is fear. What specific fears are holding you back from being your courageous self? Are you scared to leave a dead end job or relationship? Are you afraid to discover what your true passion is and follow it? This is a great quote that I think about whenever I need some help: "Life expands or contracts in proportion to one's courage" Anais Nin.
Top Ten Salty Foods according to new CDC reportBy · Comments
The Centers for Disease Control (CDC) just issued a new report listing the top ten sources of sodium. Personally, I think the list is a little surprising. Bread beat out deli meat and snacks, like chips and pretzels. Bread is not that high in salt per slice (80-200 mg per slice for white bread) so that probably means we're just consuming too much of it. These top ten salty foods account for 44% of the salt intake of Americans according to the CDC. Check out the ranking below:
- Bread and rolls
- Cold cuts and cured meats
- Pizza
What is Ujjayi breathing in yoga?By · Comments
Have you ever been in a yoga class and the teacher welcomed you to use Ujjayi (pronounced Ooo-jai) breathing during the practice? If you weren't sure what it was, how to do it, or why it is helpful, read on.
Ujjayi is a sanskrit term that roughly translated means expanded (uj) and victorious (jayi), so ujjayi breathing is expanded, victorious breathing. It helps expand the lungs and overcome mental distractions during your practice. The breathing technique uses both sound and sensation. It is more commonly called ocean breath.
Here are some simple steps to practice Ujjayi breathing:
Wellbeing: The Five Essential Elements – Book ReviewBy · Comments
Wellbeing: The Five Essential Elements by Tom Rath and Jim Harter is a great book. It is based on solid research, looks at wellness holistically, and provides access to an online tool to track and improve your own wellbeing. Gallup surveyed over 1,000 people in each of 150 countries covering more than 98% of the world's adult population. They are attempting to measure the quality of our wellbeing in areas like career similar to how we measure our weight or our blood pressure.
A recent study in the International Journal Sport Nutrition and Exercise Metabolism looked at fat metabolism after endurance exercise. The study participants performed the same workout of 36 minutes of running on a treadmill at 65% maximum heart rate under 2 different test conditions. One morning the participants performed the workout in a fasted state and did not eat breakfast. Another morning the participants performed the same workout after eating a small breakfast. The oxygen consumption and respiratory-exchange ratio was higher after exercise when a small breakfast was consumed. The same measurements were taken 12 hours later, and the oxygen consumption was still higher when breakfast was eaten before exercise, while the respiratory-exchange ratio was significantly lower indicating greater fat metabolism.
Easy, nutritious snacks ideas: 10 great optionsBy · Comments
Here are some of my family's favorite healthy snacks. Hope you enjoy them as much as we do!
- Hummus and pretzels
- Edamame
- Yogurt with granola
- Celery with almond butter
- Carrots and cucumbers with low fat ranch dressing
- Strawberries with dark chocolate
- Apples with honey
- Avocado with crackers
- Trail mix (I like a mix of almonds, dried cherries, and sunflower seeds)
- Cottage cheese with pineapple


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A Guest Post By Kirk Hazlett, APR, Fellow PRSA
"I know that you believe you understand what you think I said, but I'm not sure you realize that what you heard is not what I meant." This quote by Robert McCloskey had always been, for me, the perfect example of why communication as a profession is so critical.
Then a recent "Dilbert" cartoon caught my attention and really got me thinking about the perilous minefield in which public relations professionals work.
Ours is a profession founded on both actions and words.
It should go without saying that we must produce meaningful results for clients or employers if we are to consider ourselves successful.
But those results are predicated on communicating coherent messages that are received by, understood by, and accepted as beneficial by our target audiences.
That communication process begins with research that tells us who those audiences are, what their concerns/interests are, and what our mutual points of agreement are.
From that, we are able to craft messages and design programs that, ideally, will resonate with those audiences and persuade them to take a particular action. (Hopefully they won't do like Asok in the Dilbert cartoon and literally throw someone under a bus!)
What all this implies is something that public relations professor Jim Grunig said years ago and I emphasize in every one of my undergrad PR classes at Curry College. Communication is a two-way, synchronous process. I listen to you and formulate my messages for you…you listen to me and respond to me with your perceptions of what I suggested you consider. (Now, before the "i-dot/t-cross" mob get too hyper, I hasten to say that there's a heck of a lot more that goes into this process…but this is a blog post, not a graduate thesis.)
The bottom line is that, as communicators, our mission is to communicate with…not talk at…those individuals, groups, or organizations whose support we need.
And to accomplish this, we have to be acutely aware of how we present thoughts and ideas in our messages. What works in one cultural scenario may possibly go up in flames in another…witness the case of that oldie-but-goodie marketing misstep, the Chevy Nova. Great idea in English-speaking populations…not so much in a Hispanic setting.
Effective communication also requires a mutual understanding of needs, wants, and desires. The Public Relations Society of America's' new (March 2012) definition of the term "public relations" emphasizes the relationship-building aspect of the process and rightly so. Without this synchronization of relationships, communication remains a "shotgun" effort, with a broadside salvo of words that one hopes will reach and resonate with intended audiences.
And herein lies the challenge…and the opportunity…for public relations professionals. Our mission is to craft messages and programs for clients or employers that will be heard by target audiences, comprehended by target audiences, and responded to by target audiences…no buses involved (unless you're Vito Corleone!).
"The ever-increasing complexity of society is constantly changing our way of living. We are increasingly dependent on one another, and thus, more than ever before, we need mutual understanding." [Edward L. Bernays, "A definitive study of Your Future in Public Relations," 1961]
Kirk Hazlett, APR, Fellow PRSA, is Associate Professor of Communication (Undergraduate) at Curry College in Milton, MA. He also is Visiting Lecturer, Organizational and Professional Communication (Graduate), at Regis College in Weston, MA. Prior to his move into academia, Kirk practiced nonprofit and government public relations and marketing for more than 35 years in the US as well as Asia. Accredited by the Public Relations Society of America (PRSA), Kirk is a Member of PRSA's national Board of Directors and has held leadership positions with PRSA Educators Academy and PRSA Northeast District as well as with the Boston and Hawaii PRSA chapters.
Kirk makes great points. Although they may seem obvious, we often get so caught up in the day to day that don't always keep these points in mind – both in providing service to a client and in the advice given to clients. Mindfulness and practice are critical. We tackled that topic in a resent blog series that discussed media training and sound bites: http://www.newsmakergroup.com/blog/say-what-formulating-an-effective-and-accurate-sound-bite/
I think you made some very valid points. The quote attributed to Robert McCloskey is excellent based on my experience as a certified business coach with work focused on organizational leadership. A conversation between any two individuals can further progress if successful and effective … or it can send someone off course. And the key rests in making certain that the listener gets precisely what the communicator wants them to get from the conversation. That, then, becomes the job and goal of the one communicating and it's as simple as asking the listener to repeat back the take-away in terms of their understanding. All that they did get … great. And wherever there is something that needs to be restated and clarified to achieve the alignment, it becomes a rather easy task of the one communicating. Failure to have everyone 'together' is and can be very costly. Your post inspired me to blog on this topic http://thethirdzone.com/?p=1046.
Thanks for your insights
[...] PR is a profession that requires its practitioners having skills more than simply speaking well and writing well. More than words require to create an effective communication plan and to implement it. Deirdre Breakenridge well defines effective communication and talks about how to achieve it in his blog. [...]
Hi, Suzanne and Mike ~
Thanks very much for your feedback, and my apologies for the delay in responding. Between PRSA International Conference and then getting back into classroom mode, I've been a little off-schedule.
Really enjoyed reading your blog as well, Mike!
I would have to agree with the previous comments, you made some very valid points. I'm a public relations student at the University of Oregon and my professors also stress the importance of two-way communication. It is the public relations job to understand their company's target market through research to ensure the message not only gets received but also understood and accepted. Your post gets to the heart of what the field of public relations is all about.
Thank you,
Sarah Kanthack
Thanks very much, Sarah. You're absolutely correct…it's a MUTUAL understanding, and we, as public relations professionals, have to "drive the bus" on this one and not "assume" that someone else will do it for us or that "they should know this already." Sounds like your professors at University of Oregon have it nailed!
Thanks very much for reading and commenting!

subset: commoncrawl


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By tousif
via techzoo.org
Published: Oct 24 2013 / 21:19
Nowadays Developers across the world uses JavaScript frameworks like jQuery UI, ExtJs, Dojo to develop Rich Internet Applications (RIA). This JavaScript framework uses Asynchronous calls (Ajax Request) to get data from server in Json format. On server side we have plenty of frameworks like spring, Struts which can handle Asynchronous and synchronous request. In response to a Asynchronous request, Controller need to send response in Json format. For synchronous request, controller can delegate response to a View.


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text: Warning: Declaration of vB_ProfileBlock_vBSEOLikes::block_is_enabled() should be compatible with that of vB_ProfileBlock::block_is_enabled() in ..../vbseo/includes/functions_vbseo_ui_profile.php on line 52 View Profile: Crossroads - Cartographers' Guild Remember Me? Register Help Home What's New? Forum Forum Home New Posts FAQ Calendar Community Groups Albums Member List Forum Actions Mark Forums Read Quick Links Today's Posts View Site Leaders Donate Blogs Gallery Album Gallery Picture Gallery Advanced Search Member List Crossroads Crossroads Guild Applicant Find latest posts Find latest started threads View Articles View Blog Entries Likes Received (0) Likes Given (1) Mini Statistics Join Date 11-22-2012 Last Activity 05-18-2013 11:30 PM Blog Entries 0 Recent Visitors The last 3 visitor(s) to this page were: aidenprice, Larb, lastofthemany This page has had 298 visits Tab Content Crossroads's Activity About Me Post AreasLikes Received Tab Content All Crossroads Friends Photos New Activity () Please reload this page to view the 200+ new activity items that have been created. Older Activity More Activity No More Results No Recent Activity About Crossroads Basic Information Date of Birth July 15 About Crossroads Location: Rapid City, SD Interests: Gaming, Magic, Juggling, Fire-Eating Occupation: Entertainer Software Used: You guys tell, what's out there for the iPad? Statistics Total Posts Total Posts 4 Posts Per Day 0.01 General Information Last Activity 05-18-2013 11:30 PM Join Date 11-22-2012 Referrals 0 Post Areas Top Areas Of Posting 0 Likes -- Cartographer -- Default Mobile Style Contact Us Cartographers' Guild Archive Advertising Top All times are GMT -4. The time now is 05:02 PM. Powered by vBulletin® Version 4.2.2 Copyright © 2014 vBulletin Solutions, Inc. All rights reserved. Search Engine Optimization by vBSEO 3.6.1 Site Copyright © Robbie Powell 2006-2014All posted content is the sole property of the poster and may not be reused without permission, except for cross-site promotions.Digital Point modules: Sphinx-based search


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A tire shop caught fire Thursday morning on Glendale Avenue near the I-17 freeway.
The fire was able to be contained to one corner of the shop according to the Phoenix Fire Department.
At this time the Phoenix Fire department is unsure as to what may have started the fire.
No one was injured in the fire.
Copyright2013 CBS 5 (KPHO Broadcasting Corporation). All rights reserved.
3933 Washington Road
Augusta, GA 30907
(706) 650-5400
FCC Public File
(706) 650-5400
EEO Report
Closed Captioning


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Following Danica Patrick: Bashas' Supermarkets 200
By: Farrah Kaye After a long stay in Daytona, Scottsdale, Ariz., resident Danica Patrick was happy to get home to her own bed. She spent the few days between the races relaxing and getting a […]
Following Danica Patrick: The Daytona 500
By: Farrah Kaye In a Daytona 500 that saw fire, rain and a Monday night start, Danica Patrick's first NASCAR Sprint Cup series start didn't go as planned. During her Gatorade Duel, Patrick was involved […]
Pittsburgh Vintage Grand Prix Braces For Hot Weekend
From all over the country, people are arriving this weekend for the Pittsburgh Vintage Grand Prix at Schenley Park. But drivers and spectators alike are going to have to deal with an unusually hot weekend.


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I haven't used this product yet, but it arrived as stated on time and it looks good.
BSA® 4x32 mm Air Gun Scope
Item # WX2-217628
- Google+
This item is shipped directly from the factory. To see the expected shipping date, please add to your Shopping Cart. Sorry, no express shipping available. We are unable to ship factory direct items to Alaska, Hawaii, Puerto Rico or APO or FPO addresses.
This item cannot ship to Canada.
This item cannot ship internationally.
- Details & Specs
BSA® 4x32 mm Air Gun Scope for precision plinking excellence!
Air-powered accuracy improved! This Scope is built to handle the unique reverse recoil of today's magnum spring-powered air rifles, AND it can focus down to less than 10 yds.... very important for hunting.Zero in:
- 4X magnification, compact 32 mm objective size
- Adjustable objective focuses down to under 10 yds.
- Finger-adjustable 1/ 4 " MOA clicks for windage and elevation
- Nice 3" optimum eye relief for comfortable use
- F.O.V. @ 100 yds. is 17.8'
- Measures 12 3 / 4 " long, 14 ozs.
- Reviews
Customer Reviews
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BSA® Boresighter KitBuyer's Club $26.99 Non-Members $29.99
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BSA® Sweet .22® 3-9x40mm Scope, Matte BlackBuyer's Club $44.99 Non-Members $49.99


text: Comments on: Talking Points: Common languages in Maryland, pipe organ stolen from church, digital health records Back to the article » Talking Points • | March 4, 2013 | 12:00 am What are the most commonly spoken languages in Maryland? According to the U.S. census, nearly 300,000 Marylanders speak Spanish, which is by far the most common language after English. Roughly 55,000 to 56,000 speak Chinese or either French or Creole French, and nearly 40,000 speak Korean. The rest of the state's 15 most commonly spoken languages include Russian, Vietnamese, Persian,... Web URL: http://washingtonexaminer.com/article/2523236 Share this article on Facebook or Twitter Print this article


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I recently came across a nice new site called Ohh Deer (although its been around since November) who sell prints, cards, stationery, clothes and home-ware from a range of creatives, mainly illustrators and designers. They had a competition last month based on the theme of 'Stuck on Repeat', with the winners work becoming notebook covers. You can see all the entrants here or just the winners here, lots of great work!
The top 4 images are my favorites of the 8 winners they selected, by David Stelfox, Emma Pearce, Pippa Stewart and Stephen Cheetham.
The 4 below them didn't win but I like them, by Suzanne Antonelli (who graduated from my uni last year), Nancy Straughan, Rich Banks and Marina Molares.
London based graphic designer.
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Links - Website - Ask - Flickr - Pinterest
Follow @Theo_Inglis


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LOOP, TX (KCBD) - West Texas communities are remembering two teenagers that died Wednesday afternoon in a car crash near Loop, about ten miles southeast of Seagraves.
The Department of Public Safety says it happened around 2:30 p.m., one mile east of Loop, at the intersection of Highway 83 and County Road 129. DPS troopers say a Chevy pickup drove through the intersection and was hit by a Ford van.
The two teens in the pickup, 17-year-old Dylan Bratcher of Loop, and 15-year-old Abraham Remple of Seminole, were pronounced dead at the scene. The driver of the van had minor injuries.
Just hours after the crash, the boy's fiends gathered as the sun set, at a place the two teens made memories, the Loop Longhorn Stadium, for a candlelight vigil. The two teens shared a passion for life in school, at church and on the field.
"Our total population is 250 to 300 people so when an accident happens you know in your heart you know this person and that was the fear that ran through our community today...was we knew whoever was in that accident and we were close to them," says Loop ISD Principal Charla Scott.
This community was close to the teens, a testimony to the number of people inside Loop Longhorn Stadium to honor their memory.
15-year-old Abraham Remple and 17-year-old Dylan Bratcher died Wednesday afternoon, and as the sun began to set, friends embrace one another, shed tears, shared prayers and stories.
So many asked why? Why did this happen? "It's the impossible question. I tried to talk to my students and tell them it's a natural question. I strongly believe God is understanding and he would expect us to ask that question," says Scott.
It is faith this community leans on. "We have lost two very sweet Christian young men and they will be greatly missed - we want the families to know our prayers are with them and they can rely on our community for support," says Scott.
Hundreds of candles lit the West Texas sky over Longhorn Stadium. "I've been to both homes, there is a strong sense of faith and both families have bibles out searching for scripture."
"It's unbelievable its just surreal. It doesn't feel like it happened even though sorrow and grief is evident that it has."
The flames honoring the boys will fade, but the legacy these two young men leave behind will shine forever. "It's hard to believe we lost those 2 young men."
Both families told KCBD they need your thoughts and prayers. Churches in Seminole and Seagraves held vigils on Wednesday night as well. Even though school is out for the summer, counselors will be available on the Loop campus for students if they need someone to talk to.
Copyright 2010 KCBD. All rights reserved.
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Sarah Burrill w/ Tad Price @ Harvest Gallery Wine Bar
When: Sun Oct 14th
7:30 pm - 10:30 pm
Where: Harvest Gallery Wine Bar | 776 Main St | Dennis Village
Sarah's music is nothing short of contagious. Whether belting out the blues, singing about her pajamas, or covering classics from the 60s to songs from the present day, this nationally acclaimed singer and songwriter will "wow" you with her voice, musical talent, charisma, and sense of humor.
See more events with tags: cape cod chat house sarah burrill blues 60s


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Osteoarthritis Health Center
Understanding Arthritis -- the Basics
What Is Arthritis?
Arthritis includes a variety of inflammatory and noninflammatory joint diseases such as osteoarthritis, gout, rheumatoid arthritis, and juvenile rheumatoid arthritis.
Although the term arthritis is applied to a wide variety of disorders, arthritis means inflammation of a joint, whether the result of a disease, an infection, a genetic defect, or some other cause.
Understanding Arthritis
Find out more about arthritis:
Arthritis inflammation causes pain, stiffness, and swelling in the joints and surrounding tissues. Many people mistakenly perceive arthritis as any kind of pain or discomfort associated with body movement, including low back pain, bursitis, tendinitis, and general stiffness or pain in the joints. However, these symptoms may not be caused by arthritis. A doctor needs to confirm a diagnosis of arthritis.
For many, but not all, arthritis seems to be an inevitable part of aging. While there are no signs of long-lasting cures in the immediate future, advances in both conventional medical treatment and alternative therapies have made living with arthritis more bearable.
The Major Types of Arthritis
Osteoarthritis, or degenerative joint disease, refers to the pain and swelling that can result from the progressive loss of cartilage in the joints. It is the most common form of arthritis, affecting nearly 27 million adults in the United States, particularly older adults. In osteoarthritis, the protective cartilage that cushions the ends of bones within joints gradually wears away, which is why it is sometimes called "wear and tear" arthritis. It can affect almost any joint in the body, but commonly involves the weight-bearing joints: the knees, hips, and spine. It can also affect the fingers and any joint with previous injury from trauma, infection, or inflammation. The inner bone surfaces become exposed and rub together, and in some cases, bony spurs develop on the edges of joints, causing damage to muscles and nerves, pain, deformity, and difficulty moving.
Although the mechanism behind osteoarthritis is unknown, some people appear to have a genetic predisposition to degenerative joint disorders. This is often the case for people who develop it at an early age. Other causes of osteoarthritis include:
- Misuse of anabolic steroids (used by some athletes).
- Trauma to joint surfaces.
- Being overweight, which can cause early and more rapid progression of joint problems, especially in the knee.
In many people, the onset of osteoarthritis is gradual and has no serious debilitating effect in the beginning, although it can change the shape and appearance of a joint. Bony growths called spurs and gnarled joints may cause painful nerve damage, along with significant changes in posture and mobility.
Rheumatoid arthritis can occur at any age, but generally begins to affect people between ages 30 and 50. It affects women two to three times more often than men. It is the second most common form of arthritis, affecting 2 million people or more in the United States. Rheumatoid arthritis is characterized by inflammation, swelling, and pain in the hands, especially the knuckles and next closest finger joints, as well as in the wrists, elbows, shoulders, knees, and feet. Generalized fatigue can also occur. Rheumatoid arthritis can also cause damage to other parts of the body, including the lungs, eyes, nerves, and skin. The discomfort of rheumatoid arthritis usually develops and worsens over weeks or months and tends to be most severe upon awakening.
WebMD Medical Reference


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I don't usually pay much attention to these kinds of Facebook pictures, but this gets special mention because of the last panel. This is not because it has spelling errors or because it is offensive, but because it is illogical. I don't think I have to explain why.
If you click on the picture, you will be directed to the Facebook post in question.
- fandom-ninja-potato likes this
- clementineandfriends likes this
- flummoxingfog likes this
- belieber8797 reblogged this from morisenshisun
- morisenshisun posted this


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Creatures of the Night
"It's a weird, closeted hobby I've harbored for forty years," said Turtle Conservancy founder Eric Goode last night. "My mother gave me a tortoise when I was five, and, obviously, I didn't grow out of the phase." The inaugural Turtle Ball drew friends and colleagues of the hotelier and restaurateur from as far away as the UK and Kuala Lumpur, with philanthropists, movie stars, and artists all uniting at the Bowery Hotel to raise awareness about endangered amphibious creatures, as well as funds for Goode's Conservancy.
"There's something spiritual about turtles, something soothing," Goode said. And his friend, the designer Victoria Bartlett, agreed: "I think it's phenomenal how long they've been around, and they're still wearing the same clothes!" The evening's emcee, Sandra Bernhard, seconded the notion: "The idea that turtles have survived everything for so long is really inspiring." It was tempting to detect a tinge of nostalgia for the past in all the talk about longevity. One picture by Michael Halsband in the silent auction showcased the cast of characters that partied at Area, the legendary nightclub that Goode founded with his brother in 1983. Pointing to a woman in the photo, Bartlett said, "I used to be in a band with her, called Cheap Date—I've been around quite a while."
J.Crew's Jenna Lyons found another reason to get behind the turtles' cause. "I do not snap at people," she said, "but it's a trait I think I should develop for fashion week."


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Throw darts at the no-frills board the pros use. The Brittany Bristle Dartboard is regulation size, in case you want to hone your skills for competition. It's made of self-healing bristle board and even if you hit the bullseye multiple times, the surface stays intact. The ring of numbers rotates, so no scoring area gets overused and the board lasts longer. Use with steel-tipped darts (sold separately). Imported. 1-1/2Dx18" dia.
- Self-healing bristle board
- Moveable numbers ring extends board life
- Regulation size
- Uses steel-tipped darts, sold separately
- Games Included: Darts
- Number of Players: 1 or More Players
- Number of Games: 1
- Dart Board Target Area: 18.0 "
- Surface Material: Bristle Board
- Frame Material: Hardwood
- Care and Cleaning: Wipe Clean With a Dry Cloth
- Manufacturer's Suggested Age: 12 Years and Up
- Dimensions: 18.0 " H x 18.0 " L x 1.5 " W
- Weight: 12.0 Lb.
- Battery: no battery used
- Assembly Details: no assembly required
special offers and deals.
other offers.
free standard shipping with $50 purchase, offer details.
other Info.
- 548547
- 091-17-0526
- Made in the USA or Imported


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Inspections, Compliance, Enforcement, and Criminal Investigations
S & F Enterprises 30-Jan-04
Department of Health and Human Services
Public Health Service
Baltimore District Office
January 30, 2004
Mr. Daniel A. Albisu, President
S & F Enterprises D.B.A. Ziggy's Finest
35 New York Avenue NE
Washington, DC 20002
Dear Mr. Albisu:
The Food and Drug Administration (FDA) inspected your food storage warehouse located at 35 New York Avenue NE Washington, DC 20002 on October 29 and 31st, 2003. The inspection revealed numerous deviations from the Good Manufacturing Practice (GMP) Regulations, Title 21, Code of Federal Regulations (CFR), Part 110. At the conclusion of the inspection, you were issued a Form FDA 483, Inspectional Observations (copy enclosed), which describes the insanitary conditions observed in your firm during the inspection. These conditions cause the products stored in your facility to be adulterated within the meaning of Section 402(a)(4) of the Federal Food, Drug, and Cosmetic Act . Effective measures are not being taken to protect against the contamination of food on the premises by pests, in violation of 21 CFR 110.35(c). Specific examples include:
- A live mouse observed inside a box of [redacted] Macaroni stored on top of the cooler in the northeast part of the warehouse;
- Two dead mice observed on a glue trap by the front door under a pallet of canned product at the northeast comer of the warehouse;
- A cardboard box of [redacted] Macaroni had a hole at the bottom left side. Six 1 pound inner packages also had holes varying from 3" by 2" at the largest to 1" by 3/4" at the smallest. Holes in food packaging allow the food inside to be accessed by pests, thereby giving rise to an insanitary condition;
- A cardboard box of [redacted] Macaroni had a hole at the bottom right side. Twelve 1 pound inner packages also had holes varying from 5" by 4" at the largest to 3/4" by 3/4" at the smallest sizes;
- A case of Pepperoncino located at the northwest side of the warehouse had a hole 4" by 7";
- Rodent excreta pellets were observed in eight different areas of the warehouse. Numbers of pellets ranged from 33 to 7. Four of the sites were in proximity to stored food articles.
The investigator also noted failure to maintain buildings in repair sufficient to prevent food from becoming adulterated, in violation of 21 CFR 110.35(a). Specifically,
- A hole in the wall/floor juncture of the second floor stairway landing along the northwest side of the warehouse;
- A hole in the wall by the window frame along the second floor, southeast side of the warehouse.
You should take prompt action to correct these deviations. Failure to do so may result in regulatory action being initiated by the FDA without further notice, including seizure and/or injunction. This letter may not list all the deviations at your facility. You are responsible for ensuring that your facility operates in compliance with the Act and the Good Manufacturing Practice regulations, 21 CFR Part 110. You are responsible for implementing procedures to prevent further violations of the Act and all applicable regulations.
Please notify this office in writing, within 15 working days of receipt of this letter, of the specific steps you have taken to correct the noted violations and to prevent recurrence. Your response should outline the specific things that you are doing to correct these deviations. You should include in your response documentation and written verification procedures or other useful information that would assist us in evaluating your corrections. If you cannot complete all corrections before you respond, we expect that you will explain the reason for your delay and state when you will correct any remaining deviations.
Your reply should be sent to the Food and Drug Administration, 6000 Metro Drive, Suite 101, Baltimore, Maryland 21215, Attention: Elizabeth Laudig, Compliance Officer. Ms. Laudig can be reached at (410) 779-5441.
Lee Bowers
Baltimore District Director


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Kristi Gorenson is a fill-in anchor and reporter for KREM 2 NEWS.. She joined the KREM 2 NEWS team in December of 1997.
Originally from Puyallup, Washington, Kristi received a bachelors degree in broadcast communications from Washington State University in 1992. She started her broadcast career in 1992 at KLEW-TV in Lewiston, Idaho, as an anchor/reporter.
In 1994 Kristi moved on to KLEW's sister station KEPR-TV in Pasco, Washington, where she worked as an anchor-reporter through 1997.
During her time at KREM, Kristi has covered a variety of different stories, including the Spokane serial killer investigation and consumer affairs stories. She won a regional award from the Associated Press for a feature story on the "Kool Aid Kid" , the story of a young boy who was monopolizing on the fans at Seahawks Training camp at Eastern Washington University by selling Kool Aid.
Kristi enjoys spending time with her family as well as a variety of outdoor activities including snow skiing, hiking and snowshoeing.
You can contact Kristi at


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Comments on Donor spotlight: A century of achievement, the commitment of a lifetime If your life spanned nearly an entire century of American history, how would you want your accomplishments to be recognized? When 99-year-old engineer, inventor, and entrepreneur Bruce Del Mar considered his personal legacy, he reached out to the Smithsonian, leading to the donation of several artifacts and a generous gift to the National Museum of American History and the National Air and Space Museum. TypePad 2012-11-28T22:50:45Z NMAH http://blog.americanhistory.si.edu/osaycanyousee/ tag:typepad.com,2003:http://blog.americanhistory.si.edu/osaycanyousee/2012/11/donor-spotlight-a-century-of-achievement-the-commitment-of-a-lifetime/comments/atom.xml/ Paolo Rodriguez commented on 'Donor spotlight: A century of achievement, the commitment of a lifetime' tag:typepad.com,2003:6a00e553a80e108834017d3e542e4a970c 2012-12-01T01:25:48Z 2012-12-01T21:02:21Z Paolo Rodriguez http://paolorodriguez.com How long will this be on display?
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Who plays who in the last 16 of the Accenture World Matchplay Championships in Melbourne...
Listed below is the Quarter Final draw for teh Accenture World Matchplay Championships at the Metropolitan Golf Club in Melbourne, Australia.
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Kate Upton continues within the more fashion oriented side of modeling with this glamorous photo shoot for Interview Russia. Shot by Elle Muliarchyk and styled by Vanessa Traina, Upton is looking fantastic. We wish there was more images available for viewing! Check out a few photos from the shoot above in our gallery.
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Cheney, WA (Sports Network) - Venky Jois had 22 points and 13 rebounds to help the Eastern Washington Eagles overcome a second half deficit to defeat the Cal State Fullerton Titans, 79-75, in non-conference action at Reese Court.
Justin Crosgile tallied 16 points, 10 rebounds, and six assists for EWU (2-5). Thomas Reuter also scored 16 points, and Parker Kelly chipped in 12 points off the bench.
For Fullerton (3-3), Kwame Vaughn put up 22 points and D.J. Seeley scored 21 points.
EWU outshot Fullerton from the field in the first half, 46.9 percent to 44.7 percent, but the Titans were able to take a 46-39 lead into intermission thanks to a 6-of-12 showing from three-point range.
Fullerton's lead grew to nine at the 15:42 mark of the second half before EWU started to mount its comeback. With the game tied 64-64 with just over four minutes remaining, Jeffery Forbes drilled a jumper to give the Eagles the lead, and they were able to hold on by making 7-of-8 from the free throw line in the final minute.
The Eagles committed a game-high 19 turnovers, but they were able to make up for those miscues by outrebounding Fullerton, 40-33.
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Sydney RECOMMENDATIONS See all
Seeing an Opera in Sydney
By Viator, August 2014
While there is much more to Sydney Opera House than opera, it has to be Australia's most exciting venue to watch a performance by the world-renowned, Opera Australia. Predating the Sydney Opera House (which was opened in 1973) by almost 20 years, Opera Australia brought high-end culture to a country that was crying out for sophisticated and artistic entertainment, and remains to this day Australia's largest and most productive performing arts organization with over 600 performances a year.
It is easy to plan your night at the opera because the season is scheduled at least a year in advance. Novices can pick their way through the maze of operas or work out which opera might best suit them.
For a night at the opera with a difference, Sydney visitors might wish to plan their trip to coincide with the once yearly opera performance that takes place on the Sydney Harbour. This fantastic show began in 2012 and runs every March - April. The harbour performance is a one-off opportunity to watch a world-renowned opera take place on a floating stage with the world's most spectacular natural harbour as a backdrop. You may not be inside the famous Sydney Opera House, but you get to see its famous sails, along with the Sydney Harbour Bridge and the city's glittering North Shore.
Tours & Tickets
Opera Performance at the Sydney Opera House
Catch one the many amazing performances by Opera Australia at the World Heritage-listed Sydney Opera House. With your choice of seating, the 2014 season ... Read more
Sydney, Australia
Duration: Varies
Sydney Opera House and Sydney Symphony Orchestra Dinner Package
Music lovers - why not enjoy dinner, guided tour of the Sydney Opera House and a Sydney Symphony Orchestra performance when you're next in Sydney. Enjoy a ... Read more
Sydney, Australia
Duration: At leisure
Sydney Opera House and Australian Ballet Dinner Package
A must-do Sydney Opera House experience for lovers of ballet! This guided evening tour of the UNESCO World Heritage listed Opera House also includes a 3-course ... Read more
Sydney, Australia
Duration: 6 hours (approx.)
Sydney Opera House: Summer at the House Performance Ticket and Tour
Grab the chance to see one of the top-notch 'Summer at the House' performances at the World Heritage-listed Sydney Opera House. See the cabaret-style circus ... Read more
Sydney, Australia
Duration: Varies
New Year's Eve Opera Performance at the Sydney Opera House
Ring in the New Year at the Sydney Opera House with passion, fireworks, celebration and 'La bohéme'! Be swept up in the emotion of Puccini's famous opera, ... Read more
Sydney, Australia
Duration: 2 hours 45 minutes (approx.)


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President Obama: "Congress is only going to act if they hear from you—the American people." #DemandAction, http://t.co/DOMTxo63Ad
TONIGHT: President Obama at the White House Correspondents' Dinner, hosted by @ConanOBrien. Watch live at 9:45 ET:
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Latin Music superstars Pitbull, Marc Anthony, Thalía, Jencarlos Canela to perform at 2013 Premios Juventud
Univision celebrities Alejandra Espinoza, Rodner Figueroa, Carlos Calderón, and Amores Verdaderos leading lady Eiza González confirmed to host pre-show
Eugenio Derbez to receive Supernova Award
Celebrating its 10th birthday with a sensational "beach bash," the 2013 Premios Juventud youth awards will air LIVE on the Univision Network on Thursday, July 18, 2013 at 7 p.m. ET/PT (6 p.m. Central)
MIAMI – JUNE 25, 2013 – With almost a month to go before the big event, the lineup of Latin music top stars confirmed to perform on Univision's Premios Juventud (Youth Awards) is shaping up to be the biggest ever. The coolest, most unconventional awards ceremony on Spanish-language TV, the 10th Annual Edition of Premios Juventud will air on the Univision Network LIVE from the BankUnited Center at the University of Miami on Thursday, July 18, 2013 at 7:00 p.m. ET/PT (6 p.m. Central). The talent arrival pre-show will be hosted by Univision celebrities Alejandra Espinoza, Rodner Figueroa, Carlos Calderón, and Amores Verdaderos leading lady, Eiza González.
The first group of performers signed up for the spectacular show includes three chart-busting luminaries that are all nominated for 2013 Premios Juventud awards: Pitbull (five nominations), Thalía (four nominations), and Marc Anthony (one nomination). Also confirmed is pop singer/songwriter Jencarlos Canela, performing the world TV debut of his new single, I Love It.
In addition, Maite Perroni and Leslie Grace will also present world premieres, while up-and-coming singer Becky G, Angel & Khris, and DJ Chino ft. Fito Blanco and Papayo will add their unique styles to the celebration as well. Many more names will be announced in the coming weeks.
With five new categories added this year, and more than 90 celebrity nominees vying for awards in the areas of Music, Movies, Novelas, Sports, and Pop Culture, the Premios Juventud broadcast will celebrate its 10th birthday by hosting a sensational, surprise-filled "beach bash" in keeping with Miami's world-famous fun-in-the-sun South Beach scene. Dozens of A-list Hispanic celebrities are expected to attend the event as performers, presenters, and guests.
As part of the celebration, for the first time ever, Premios Juventud will introduce the Summer Song 2013 category, in which the winner will become the official song of Univision's summer on-air promotions. The nominees are Jencarlos Canela with his new single, I Love It, Angel & Khris with My Corazón, and DJ Chino featuring Fito Blanco and Papayo with Si Te Agarro. Fans can already start voting via PremiosJuventud.com and Twitter.
In addition to the spectacular musical numbers and unconventional award presentations, Premios Juventud 2013 will bestow its prestigious "Supernova Award" upon the hugely popular Mexican comedian Eugenio Derbez in recognition of his distinguished and wide-reaching career. Past recipients of the "Supernova" award include Fernando Colunga, Shakira, Maná, Ricardo Arjona, Chayanne, and Antonio Banderas.
To amplify TV viewing and provide an even more immersive digital experience, PremiosJuventud.com will have a comprehensive digital offering for fans, which will be unveiled beginning today and run through the night of the awards show. Digital integrations include:
* Premios Juventud Over the Past 10 Years. In celebration of the 10th Anniversary of "Premios Juventud," fans can relive the best video moments of the show since its inception in 2004; from the top winners, the best wow moments, red carpet events and much, much more.
* Special: Ten Years of Premios Juventud Fashion. Noted fashionista Rodner Figueroa celebrates a decade of couture hosting a weekly video recap of the best and worst dressed from past Premios Juventud award shows. Figueroa also gives fans the inside look on how to achieve the Premios Juventud 2013 Red Carpet Look.
* Worldwide Debuts of Anticipated Singles. PremiosJuventud.com will unveil the exclusive international debut of a duet sung by "The Corrido Phenomenon," Gerardo Ortiz, and his younger brother, Kevin Ortiz, who will be singing together for the first time. Additionally, Venezuelan breakout artist Jonathan Moly and producer Sergio George will unveil an adaptation of his new song, Mi Linda Princesa, exclusively for PremiosJuventud.com.
* Vote for the Summer Song 2013. For the first time ever, fans will have the opportunity to vote for their favorite song of summer 2013 via PremiosJuventud.com and by using the hashtags #pjiloveit, #pjsiteagarro and #pjmycorazon on Twitter. Voting is now open. The winner of the Summer Song 2013 will be unveiled LIVE during the Premios Juventud telecast on July 18. The Summer Song 2013 will also become the official theme song promoting Univision's summer line-up in a six-week Univision/UniMás summer promotional campaign.
* Exclusive Celebrity Access. Special interviews will be featured on PremiosJuventud.com including exclusive footage with Maite Perroni, Leslie Grace, Becky G, El Daza, Abraham Mateo, Kat Dahlia, Jonathan Moly, Sonus, Kevin Ortiz, Valentino and Jencarlos Canela.
* Unique Video Content from Univision Stars. Marisela Demontecristo, winner of "Nuestra Belleza Latina" 2013, will give PremiosJuventud.com exclusive access to her styling room to show fans how she will be getting ready for the awards show. Additionally, Alejandra Espinoza will share insights into her career since first stepping foot on the Premios Juventud Red Carpet in 2007. She will also give fans a preview of the wardrobe she will wear as carpet host. Finally, alongside Carlos Calderón and Rodner Figueroa, Espinoza will also give fans a sneak peek of what will take place on this year's red carpet.
The dedicated Premios Juventud Channel is also LIVE on the Univision Radio app featuring the biggest and most popular artists and nominated songs, including Jesse & Joy, Juanes, Larry Hernandez, Banda El Recodo, Robi "Draco" Rosa, Romeo Santos, Vicente Fernández, Victor Manuelle, Wisin & Yandel, Daddy Yankee, Beto Cuevas, and Jenni Rivera.
Since its debut in 2004, the Premios Juventud youth awards show has consistently been a phenomenal ratings success. In July 2012, the live broadcast of Premios Juventud delivered an average audience of 4.1 million Total Viewers 2+ and positioned Univision as the No. 1 broadcast network during the entire night among Adults 18-34 for the fifth consecutive year.
Social media activities for Premios Juventud made it the second most engaged awards show in 2012, regardless of language. This year's 10th birthday beach bash will take fans' access to their favorite stars and key moments to a new level. In the lead to the broadcast, fans can get the latest – from the celebrities participating to access to key history moments of Premios Juventud– by joining the conversation on Twitter via @PremiosJuventud and using the hashtag #PremiosJuventud, as well as comment along with others on https://www.facebook.com/PremiosJuventud and UnivisionPremios on Instagram.
Source: Univision Press Release


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Created: 10/21/2013 11:33 AM KSTP.com
By: Jennie Olson
President Barack Obama on Monday said there was "no excuse" for the cascade of computer problems that have marred the rollout of key elements in his health care law but declared he was confident the administration would be able to fix the issues.
"There's no sugarcoating it," Obama said. "Nobody is more frustrated than I am."
The president said his administration was doing "everything we can possibly do" to get the federally run websites up and running. And he guaranteed that everyone who wants to get insurance through the new health care exchanges will be able to.


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Otterburn Bed and Breakfast
Open April to September, David and Elaine Crane will greet you with a warm and friendly welcome at Otterburn Bed and Breakfast. This modern bed and breakfast is located in the picturesque village of Dervaig, overlooking Loch Cuin, where you can be sure to see an array of exciting bird life and even spot the local otters and deer. Sea eagles are seen regularly over the garden and in the locality, as are other birds of prey such as buzzard, golden eagle, hen harrier and sparrowhawk.
At Otterburn you will get to meet Molly, our young Collie X. She is very friendly, loves to meet and greet our guests and enjoys playing with her numerous toys and balls!
Dervaig is located at the head of Loch Cuin between Tobermory and Calgary Bay and renowned to be one of the prettiest villages on the island. Founded in the late 18th century, Dervaig was built by the laird, MacLean of Coll, to provide accommodation for the nearby Quinnish Estate.
Kilmore Church in the village, is the only Irish towered chapel in Scotland (the spire of which looks like a sharpened pencil) and is also famous for its unusual stained glass windows. Dervaig has a hotel in the village serving excellent meals (renowned for its platters of local produce) and another restaurant within two miles. On the whole, Dervaig is an ideal retreat and convenient base for touring and exploring around the north of Mull and beyond.
Otterburn has two extremely spacious rooms on the first floor - one king-size double and one twin - both with superb views over the Cuin. The rooms have large en-suite bathrooms, comfortable sitting areas, and are well-equipped with TV, DVD player, tea and coffee making facilities and hairdryer. Breakfast is served in the bay window area on the ground floor enabling guests to watch the abundant birdlife in the garden and the occasional sea eagle passing by.
Otterburn is a non-smoking establishment, including the grounds.
See the accommodation page for more details.
Breakfast and Packed Lunch
Breakfasts at Otterburn are well cooked and hearty – served with an Irish twist (to reflect David and Elaine's origins in Northern Ireland). We can also provide packed lunches for those 'all day' bird watching, cycle or walking trips.
Availability and Booking
We are now taking bookings for 2014. Please check here for availability. Making an advance booking is easy. Either e-mail us via this booking link or ring us on 01688 400685. We will try to respond to e-mails within 24 hours.
Our prices for 2014 range between £35 and £45 per person per night bed & breakfast depending on the number of nights you stay. We regret that we are unable to process payments by credit or debit card. We accept cash (Pounds Sterling) and cheques raised on a UK bank account. View the full 2014 Tariff here.
David and Elaine Crane,
Otterburn Bed and Breakfast, Cuin Croft, Dervaig, Isle of Mull, PA75 6QL


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We love this and have made it several times. I like to use whole wheat pasta but have never found whole wheat ditalini, so I usually sub small shells or orzo. I also add feta when serving as a main dish, to make it more rounded and filling. I agree with the other reviewer that corn fits better than cucumber, but obviously that will add starch and calories, if that's a concern.
Summer Black Bean and Pasta Salad
Drain the pasta, and rinse it immediately with cold water to cool it quickly. If you can't find ditalini pasta, substitute tubetti or small elbow macaroni.
Yield: 4 servings (serving size: 1 1/2 cups pasta and 1 lime wedge)
How to Cook Pasta
More From Cooking Light
Nutritional Information
Amount per serving
- Calories: 214
- Calories from fat: 30%
- Fat: 7.1g
- Saturated fat: 1.1g
- Monounsaturated fat: 4.4g
- Polyunsaturated fat: 0.9g
- Protein: 7.3g
- Carbohydrate: 35.5g
- Fiber: 7.2g
- Cholesterol: 0.0mg
- Iron: 2.4mg
- Sodium: 656mg
- Calcium: 47mg
- 3/4 cup uncooked ditalini (very short tube-shaped macaroni, 3 ounces)
- 1 1/2 cups halved grape tomatoes
- 3/4 cup diced peeled avocado
- 1/2 cup chopped seeded poblano chile (about 1)
- 1/2 cup chopped cucumber
- 1/3 cup chopped red onion
- 2 tablespoons chopped fresh cilantro
- 1 (15-ounce) can black beans, drained and rinsed
- 2 teaspoons grated lime rind
- 2 tablespoons fresh lime juice
- 1 tablespoon cider vinegar
- 2 teaspoons extravirgin olive oil
- 3/4 teaspoon bottled minced garlic
- 3/4 teaspoon salt
- 1/8 teaspoon ground red pepper
- 1 medium lime, cut in 4 wedges
- Cook pasta according to package directions, omitting salt and fat. Drain and cool completely.
- Combine the tomatoes, avocado, poblano, cucumber, onion, cilantro, and beans in a medium bowl, stirring well. Combine rind, juice, vinegar, oil, garlic, salt, and pepper in a small bowl, stirring well with a whisk. Add pasta and lime mixture to bean mixture; toss to combine. Serve with lime wedges.
My Notes
Only you will be able to view, print, and edit this note.Add Note
Summer Black Bean and Pasta Salad Recipe at a Glance
- COURSE: Main Dishes, Salads
- CONVENIENCE: Quick/Easy
- CUISINE: Southwest
- MAIN INGREDIENT: Vegetables
- DIETARY CONSIDERATION: Low Cholesterol, Low Saturated Fat
- OCCASION: Summer
- PUBLICATION: Cooking Light
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174 results for "rushel shell"
Rushel Shell #7 RB
Position battle update: West Virginia RBsJake Trotter
This week we've been highlighting the key position battles for every program in the Big 12. We continue this series with West Virginia, which has several capable running backs, but one football to hand off. Here's where the battle stands: Conte...Blog | August 20, 2014
Photo results for "rushel shell"
West Virginia v MarylandSeptember 13, 2014
West Virginia v AlabamaAugust 30, 2014
Rutgers v PittsburghNovember 24, 2012
Rutgers v PittsburghNovember 24, 2012
All-Big 12 ballot roundtableJake Trotter
Earlier this morning we gave you our preseason All-Big 12 picks. Here are some additional thoughts: The other player I most considered for Offensive Player of the Year? Chatmon: Tyler Lockett was tough to leave in Bryce Petty's wake. The Kansas...Blog | July 09, 2014
Video results for "rushel shell"
3Q WVU C. Trickett pass,to R. Shell for 19 yds for a 1ST downAugust 30, 2014
2Q WVU R. Shell run for 14 yds for a 1ST downAugust 30, 2014
- 00:17
Q&A: West Virginia signee Dravon HenryBrandon Chatmon
Dravon Henry could be the next great player from Aliquippa, Pennsylvania. The No. 140 player in the ESPN 300 for the Class of 2014, Henry turned down offers from Pittsburgh, Alabama, Florida State, Ohio State and others to sign with West Virginia....Blog | June 20, 2014
Strong and weak: West VirginiaBrandon Chatmon
The last two weeks, we've been examining the strongest and weakest positions for each team in the Big 12 heading into the fall. On Friday, we continue the series with West Virginia. Strongest position: Running back The Mountaineers running b...Blog | May 23, 2014
Ranking the Big 12 position-by-positionJake Trotter
Two weeks ago, we ranked every team in the Big 12 position-by-position coming out of the spring. Putting that together, we've ranked the overall league position-by-position. In other words, what is the league's strongest position? What is its weakest...Blog | May 21, 2014
Q&A: West Virginia assistant JaJuan SeiderBrandon Chatmon
With a meeting room full of talented running backs set to battle for carries, West Virginia could have the deepest position group in the Big 12 this fall. Running backs coach JaJuan Seider took some time to chat with ESPN.com about the depth at th...Blog | May 14, 2014
Tide schedule preview: West VirginiaAlex Scarborough
Editor's note: We're taking steps to get you ready for every one of Alabama's regular season opponents. Every Friday we'll go through each week of the schedule, starting with the season-opener against West Virginia and closing with the finale against...Blog | May 09, 2014
Poll: Big 12's best offensive unit?Jake Trotter
For the past two weeks, we've been ranking the best units in the Big 12 by position. Now, in our weekly poll, we're asking for your opinion: Who has the league's best offensive unit regardless of position? We're going to exclude the quarterback...Blog | May 08, 2014
West Virginia spring wrapJake Trotter
Three things we learned in the spring about the West Virginia Mountaineers: 1. Clint Trickett is the heavy favorite to open as the starting QB: Paul Millard and junior college transfer Skyler Howard battled to make a run at the starting QB job dur...Blog | May 01, 2014
Big 12 post-spring breakdown: RBsJake Trotter
With spring ball done, we're reexamining and reranking the positional situations of every Big 12 team, continuing Tuesday with running backs. These outlooks will look different in August. But here's how we see them post-spring: 1. West Virginia ...Blog | April 29, 2014
Big 12 spring stars, Part 2Brandon Chatmon
Spring football is coming to a close in the Big 12, with several players making a move in their respective programs and securing or improving their roles on the team. We reviewed the Big 12's stars of the spring by taking a closer look at their pre-s...Blog | April 25, 2014
Spring game review: West VirginiaJake Trotter
West Virginia capped its spring drills with the Gold-Blue game on Saturday. Here's a recap of what happened: Best offensive performance: The other quarterbacks had their moments, but veteran Paul Millard was the steadiest, completing 14 of 19 pass...Blog | April 14, 2014
Spring game preview: West VirginiaMax Olson
West Virginia finishes its spring practice schedule with the annual Gold-Blue spring football game this weekend. Here's what you need to know: When: 1 p.m. ET Saturday Where: Milan Puskar Stadium, Morgantown, W.Va. What to watch for: The...Blog | April 11, 2014
Poll: Top Big 12 offensive newcomer?Jake Trotter
In 2013, Charles Sims transferred to West Virginia from Houston for his final college season. After finishing third in the league in rushing, Sims deservedly was named the Big 12 Offensive Newcomer of the Year. This year, several offensive transfe...Blog | April 10, 2014
Garrison emerging for West VirginiaJake Trotter
Even with All-Big 12 performer Charles Sims moving on to the NFL, West Virginia still has an abundance of riches at running back. Dreamius Smith was the No. 1 juco back in the country last year, and finished second on the team in rushing. And d...Blog | April 08, 2014
WVU's Shell ready to 'bring it' this springJake Trotter
This spring, West Virginia linebacker Nick Kwiatkoski discovered firsthand the power Rushel Shell can bring between the tackles. During a team drill, the two fiercely collided at the line of scrimmage. Kwiatkoski bounced off one way. Shell bounced of...Blog | April 01, 2014


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Fleet One Local Sites
5,000 - 10,000 downloadsAdd this app to your listsTweets por @AppsZoom
Fleet One's Local Fuel Card replaces credit/debit cards or cash and gives you unparalleled control over your fleet fuel expenses. There's a reason Fleet One is the fastest growing fuel card company in the industry.
•You control who uses your business' fuel cards, where they may use it and for what products
•Line-item purchase detail on every transaction means easier reconciliation; no need for receipts
•Online account management that lets you make changes to your account with just a few mouse clicks
Visit www.FleetOne.com/Local for more information and to see what you've been missing, whether you're new to fuel cards or ready for an upgrade from your current provider.
The Fleet One Local Sites Finder lets you search all Fleet One accepting sites and view their retail fuel prices.* Around the corner or across the country, the Fleet One app means no more guessing where to get the best deal on fuel or where your drivers can swipe their card.
•Search for Fleet One Local Sites by price or by distance
•Filter search results by gasoline or diesel
•View Fleet One Local sites in a list or on a map
Download the Fleet One Local Sites App. today, and maximize the benefits of your Fleet One account. The app is free. The service is free. What are you waiting for?
*Prices may not be available on all sites, posted fuel prices represented on the Fleet One Local Site App. reflect the most current information available to Fleet One, actual site retail prices may differ.
Tags: free fleet one apps, fleet one, googlefleetonefilters, fleet.one.com/sites, www.fleetone.com, fleet one fuel filters, fleetone.com/sites, fleet one file, fleet one local sites, fleet one phone.
(54 stars)
Does not upload
(54 stars)
Half the places listed doesn't accept fleet one..
(54 stars)
Half the gas stations listed don't take the Fleet card and the prices posted are completely off... 3.19 when it's 3.89 at the pump.
(54 stars)
Only problem I had was the store was supposed ti be a Sunoco but they just changed to marathon.
(54 stars)
I wanted to use this for work b/c we use Fleet One cards, but it continuously fails to load while during a search. This app really deserves a zero star.
(54 stars)
Would be useful if the app filtered results to show which stations accept FleetOne OTR, have 18-wheeler access, etc. All the data is in their hands already. Please update!
(54 stars)
Just joined and uploaded the app. First search I found the cheapest Diesel prices within 50 miles that participate with FleetOne. Was pleasantly surprised to find HUCKS amnesty. Thank you for such a great app Miller Trucking


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Similar Movies
The most popular movies among NYTimes.com readers.
2 Readers' Reviews
HIGHLIGHT (What's this?)
March 6th, 20097:06 am
A cool and perfect a character study. Rarely have I seen a film in which the stylistic choices by a director so perfect suit the characters and material. Patient and restrained, "Dead Ringers" could have easily gone off the deep end into the macabre, but because of the control of Cronenberg's aesthetic and the breadth of Irons' performances the film retains an uncanny power right up through its emotionally shattering climax.
— Eric Slee, 91403
November 5th, 20078:23 pm
Over and over and over again; is it he; is it him? So the girl friends say. After a third of the way through this slop (and slop music)we, like the girl friends, don't care. The psychological crumbling? Jeremy Irons? Retch.
— juniperus, Roan Mountain,Tennessee


text:
An Application to Rezone from C-1 to AG has been received by the Floyd County Zoning Commission.
You are hereby notified that James Dow has filed an application with the Floyd County Zoning Commission to rezone 73.75 acres of property from C-1 to AG for the purpose of turning a golf course club house into a residence and turning the golf course into tillable ground. This property is located at 2127 – 8th Street SW in the Northwest Quarter of Section 15 and the Northeast Quarter of Section 16, Township 95 North, Range 18 West, Rockford Township, Floyd County, Iowa.
You are further notified that the Floyd County Zoning Commission will hold a Public Hearing on this request in the office of the Planning & Zoning Department on the 1st floor of the Floyd County Courthouse beginning at 9:00 A.M. on March 13, 2012, at which time you may file written or oral objection or support of said application.
(Note: Following the Zoning Commission hearing the Board of Supervisors will hold a public hearing at 10:30 A.M. to consider same.)
Floyd County Zoning Commission
By Jeff Sherman, Zoning Administrator


text:
The Tipsy Baker: Gourmet Today: roasted pears and candied celery. Right before we went to Boston last week, we had party with my uncle Luis, his wife Ana Maria, and my grandmother.
The only dish I made that didn't come from Gourmet Today was the guacamole (excellent Rick Bayless version with tomatillos) and the guests -- all natives of Guatemala -- informed me that this chunky Mexican guacamole lacked the suave, elegant texture of Guatemalan guacamole, which is essentially pureed and, of course, far superior. Having stated their case, they basically scraped the bowl clean of the barbaric Mexican guacamole and my grandmother took the dish to her place at the table and used the last bits as a relish for the rest of the meal. I served straciatella, a chicken soup with spinach and egg that was fine, and an eggplant souffle, that was also fine but didn't rise one centimeter, so I called it a frittata.
Sweet saturday: banana soft serve. It occurred to me during this week's Today's Eats post that I talk a lot about banana soft serve, but have never actually demonstrated how to make it.
I guess I just assumed that it was common knowledge. Which is the problem with being in the healthy living blog community, we tend to assume everyone know what chia seeds and coconut water is, but truthfully, we're the freaks. Banana soft serve is absolutely one of my favorite healthy diet "tricks". It looks like ice cream.
It tastes like ice cream. Pear compote - by Carina. Drop Doughnuts Recipe. Apple cream, John Barry and Valentine's day. I have a nasty cold.
I am a wreck. And I do feel that way. This has not prevented me from feeling an urgent desire to make a dessert with apples though, being them one of my many addictions. Sea Salt Caramel Rice Krispie Treats | Dash of East. I hope you all are having a great Friday!
We are in Orlando right now on a spur of the moment vacation. Today, we're going to be exploring Harry Potter World at Islands of Adventure. Lemon Cream with Blackberries. White Peaches In Rose-Water Syrup. Food blogging started out as a curious little hobby but it is morphing into a very timing consuming affair.
The essential 3 components : cooking,photographing and writing can take up a inordinate amount of my time. I have to be honest and admit that I am truly struggling to sustain the momentum while continuing to complete my work datelines. (the one that pays the bills!!) I continue to marvel at prolific bloggers who demonstrate clock-work regularity in their posting - some of whom have chocked up an enviable stash of back log which allows them to do auto-scheduled posting....
5-Ingredient Rice Crispy Treats. Going back to school?
When I was growing up, I'd often find a rice crispy treat—in that infamous turquoise wrapper—packed into my school lunchbox. So rice crispy treats remind me of school… in a good way! No-bake, and they can be gluten-free! (Or you can make squares)
Ice Cream
Pudding. Na Miotle » Icing is not difficult :) W ramach przerywnika między piernikami a porządkami powstał lukrowy domko-kościół.
Przez kilka dni 'budowałam' z lukru poszczególne elementy. Dzisiaj doczekały się połączenia w całość. Tytuł wpisu jest trochę przekorny bo montaż dachu nie był wcale taki prosty :). Niestety ze względu na bardzo dużą 'delikatność' materiałów budowlanych nie dało się niczym podeprzeć poszczególnych elementów w czasie łączenia. No ale jakoś poszło… :). The Pastry Affair - Home - Brown Butter Rice Krispie Bars.
Today I ate a peanut butter and jelly sandwich.
Creamy peanut butter, grape jelly, and white bread—transcendence. I haven't had a PB&J for years and oh it was good. Sometimes I feel like I've outgrown certain foods, like boxed macaroni and cheese, hotdogs, or PB&J. Steamed Chinese Lotus Buns Recipe 莲蓉包 (with Photo Tutorial) | Tastes of Home. I am so pleased to present today steamed Chinese lotus paste buns from my humble kitchen - I'm still a little surprised at how good they were since this was my first attempt at making steamed buns or pao/ bao at home, I guess with a bit of determination and a decent recipe, one can't go too far off the mark, yes even for a novice like yours truly.
Biting into these piping hot soft buns with just the right amount of lotus paste oozing out was pure bliss - steamed buns are one of my favourite Chinese snacks and are something I must order whenever I have dim sum at restaurants. I was a tad apprehensive before and while making the buns as I have heard that the dough for the buns may be a little tricky in different weathers but luckily the stars were aligned right today - oh and did I mention that it was a really fun process? Healthy & raw pineapple dessert | NatureInsider.com. I have some great news to share – my niece is coming to visit us for a month and this time she is bringing her boyfriend with her!
It's a huge event for our family, because we get to see them very often, once in 2-3 years. See, my brother lives in Canada and I live in Europe, some 3000 miles away… Me and my brother have a big difference in the years, he practically raised me, then got married and now has two lovely daughters which I adore – Alina & Katrin.


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ONLINE AUCTION OCTOBER 9TH inline 6-cylinder, auto transmission, believed to have 33,025 original miles, garage kept. Runs and drives. More info on website: barrrealtyauction.com. Auctioneer Stephen... More
1963 Chevrolet ``Bel Air`` 4 Dr.Sedan restoration in beautiful, fresh ``Ember Red`` factory color refinish professionally done and a quality job !! The... More
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Just in from the south is this 1963 BelAir 2 door sedan. This car started life as a six cylinder, but now sports a... More


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Icehouse 4pk Cans (In Store Only)
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Adobe Photoshop Lightroom 5 software download is available at Amazon | B&H | Adorama for $149. All versions (update and Student & Teacher version, both $79) at Amazon | B&H | Adorama.
Related posts:
stay away from this bug ridden release. wait for an update.
look at teh adobe forum.. mayn nasty bugs!
in worst case you delete wrong files because the selection in grid view is buggy.
can you post the link to the forum?
The upgrade is only $79 on Adobe's website.
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text:
There it was, hanging on the rack, the only one left. The warm and fuzzy faux fur coat was clearly a hot selling item. And, unlike most faux furs, it didn't resemble Chewbacca.
And with the pricing at just $40, I had found my new winter coat.
So I paid for it and immediately slipped it on, right there at the check-out counter, stuffing my worn peacoat into the shopping bag.
I walked out of that store with a much bigger strut than when I went in. I felt fashionable, sexy, sophisticated, and fancy in my faux fur coat.
But once the luxury had worn off, reality set in. Why did I feel fancy in it? I, a huge supporter of animal rights, had to admit to myself that it was because fur was considered luxurious.
Well, then I just felt like a horrible hypocrite. A wolf dressed up in sheep's clothing (well, actually, it looks more like mink).
Every time someone complimented me on my new coat, I felt the need to go into this long defensive explanation -- Thanks! Actually it's fake. I'd never buy a real fur coat, even if I could afford it! I'm highly against that. Those poor animals!
I knew that they could care less about where I stood on animal rights, but I was doing it more for myself ... to convince myself that I bought the coat because it was warm and chic. Not because it resembled coats that were created from animals who were kept in horrible conditions until they ultimately died.
It didn't help matters when a stranger came up to me, actually crossing the entire length of the room, to tell me that I was an evil person for wearing fur. When I gave them my memorized defense speech, they responded back with Well, that's just as bad.
If I hadn't been in a very public place, I would've cried. But the person made a valid point. Unless you're wearing a blatantly obvious faux (and if that's the case, honey, just don't wear it ... whether you're a friend or foe to the animals), who will know if your jacket is real or fake? They make assumptions, and 50% of those assumptions will probably lean toward the real thing. So there you are, a walking billboard for fur fashion.
I've since come to peace with my faux fur -- it's just too chic to give up. Plus it's getting cold as hell outside and the thing traps in heat like a greenhouse. I still give my defensive speech, but I no longer worry about what others think of me. So I may be a walking contradiction -- but at least I know I'm walking in a fake.
Do you wear faux fur? Do you think wearing faux fur is just as bad as wearing real fur?
Image via fueledbynofx/Flickr
Good for you. I don't necessarily have a problem with the real stuff, 100 years ago people didnt just use the fur, they used the meat, the bones, etc. All parts of the animal were being used to some good. Fur was a nessessity, not a luxury, at that time. That being said, I am more for the faux stuff now than the real stuff, though I'm not one of THOSE people who will cross a room to tell a complete stranger something that is none of my business. I would not have a problem necessarily wearing the real thing either. Call faux fur hypocritical if you want, i don't see it that way. It's a way to have the look and feel of luxury without having to decimate some already almost extinct population. And if people judge you for it it's there problem,not yours
Do you wear leather?
Personally, I think fur - real or fake - is pretty ugly, so I don't wear it. However, I do love leather - bags, shoes, and jackets. The idea of having real fur on me is sort of icky, and I can't really tell you why I don't feel the same about real skin (leather) - so I guess I'm a hypocrite on this one.
I think it looks ugly either way. I don't wear fur or animal print of any sort. I just think it looks tacky.
Doesn't matter to me if it is real or not, I have a leather bag and coat which to me is no different then fur.
Seriously, if someone wants to get all hot and bothered over and ASSumption that THEY made... that is THEIR problem. Since most anti-fur people protest wearing fur on the grounds of animal rights (cruel treatment, etc.) wearing fake fur is OBVIOUSLY no where near as bad.
i dont agree
I do not like fur fake or real and I would be doing the same thing explaining over and over everytime some one said anything
I create a special savings account
I put a little away at a time
I cut corners until I can afford it
Save? Who has money to save?
I plan to put it on my credit card and love the benefits of the reward program


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I love these.
This post is wonderful.
Perfect reason not to vote for this douchebag that never had to worry about money in his entire life.
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lmao the baby one is the best
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I felt it and wasn't sure, I always have thought I feel it but it just turns out to be gas, then I just waited and I felt it again, and actually SAW it!
My heart stopped, I keep staring at my belly now and waiting but nothing else is happening.. but I'm 99% positive that was a kick. I am so happy, I have been waiting for this moment for weeks now.
Baby Boy's First Kick: July 1, 2012, at about 10:45 AM
:) :) :)
I can't help but feel like this is him telling me to relax, ever since yesterday's incident I have been crunching numbers like crazy to see if me and my boyfriend can move into an apartment sometime soon, and it's been stressing me out, I couldn't sleep until 3 this morning because of it.


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From Proteopedia
|2a45, resolution 3.65Å ()
|Thrombin, with EC number 18.104.22.168
|FirstGlance, OCA, RCSB, PDBsum
|save as pdb, mmCIF, xml
Crystal structure of the complex between thrombin and the central "E" region of fibrin
Nonsubstrate interaction of thrombin with fibrinogen promotes sequential cleavage of fibrinopeptides A and B (fpA and fpB, respectively) from the latter, resulting in its conversion into fibrin. The recently established crystal structure of human thrombin in complex with the central part of human fibrin clarified the mechanism of this interaction. Here, we reveal new details of the structure and present the results of molecular modeling of the fpA- and fpB-containing portions of the Aalpha and Bbeta chains, not identified in the complex, in both fibrinogen and protofibrils. The analysis of the results reveals that in fibrinogen the fpA-containing portions are in a more favorable position to bind in the active site cleft of bound thrombin. Surface plasmon resonance experiments establish that the fpB-containing portions interact with the fibrin-derived dimeric D-D fragment, suggesting that in protofibrils they bind to the newly formed DD regions bringing fpB into the vicinity of bound thrombin. These findings provide a coherent rationale for the preferential removal of fpA from fibrinogen at the first stage of fibrin assembly and the accelerated cleavage of fpB from protofibrils and/or fibrils at the second stage.
Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly., Pechik I, Yakovlev S, Mosesson MW, Gilliland GL, Medved L, Biochemistry. 2006 Mar 21;45(11):3588-97. PMID:16533041
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
[FIBG_HUMAN] Defects in FGG are a cause of congenital afibrinogenemia (CAFBN) [MIM:202400]. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen. Note=Patients with congenital fibrinogen abnormalities can manifest different clinical pictures. Some cases are clinically silent, some show a tendency toward bleeding and some show a predisposition for thrombosis with or without bleeding. [FIBA_HUMAN] Defects in FGA are a cause of congenital afibrinogenemia (CAFBN) [MIM:202400]. This is a rare autosomal recessive disorder characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen. Note=The majority of cases of afibrinogenemia are due to truncating mutations. Variations in position Arg-35 (the site of cleavage of fibrinopeptide a by thrombin) leads to alpha-dysfibrinogenemias. Defects in FGA are a cause of amyloidosis type 8 (AMYL8) [MIM:105200]; also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash.[1] [THRB_HUMAN] Defects in F2 are the cause of factor II deficiency (FA2D) [MIM:613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding symptoms. The severity of the bleeding manifestations correlates with blood factor II levels.[2][3][4][5][6][7][8][9][10][11][12][13] Genetic variations in F2 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.[14] Defects in F2 are the cause of thrombophilia due to thrombin defect (THPH1) [MIM:188050]. It is a multifactorial disorder of hemostasis characterized by abnormal platelet aggregation in response to various agents and recurrent thrombi formation. Note=A common genetic variation in the 3-prime untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increased risk of venous thrombosis. Defects in F2 are associated with susceptibility to pregnancy loss, recurrent, type 2 (RPRGL2) [MIM:614390]. A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions.[15] [FIBB_HUMAN] Defects in FGB are a cause of congenital afibrinogenemia (CAFBN) [MIM:202400]. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen. Note=Patients with congenital fibrinogen abnormalities can manifest different clinical pictures. Some cases are clinically silent, some show a tendency toward bleeding and some show a predisposition for thrombosis with or without bleeding.
[FIBG_HUMAN] Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. [FIBA_HUMAN] Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. [THRB_HUMAN] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.[16] [FIBB_HUMAN] Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
About this Structure
2a45 is a 10 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1qvh. The November 2006 RCSB PDB Molecule of the Month feature on Fibrin by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_11. Full crystallographic information is available from OCA.
See Also
- Pechik I, Yakovlev S, Mosesson MW, Gilliland GL, Medved L. Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly. Biochemistry. 2006 Mar 21;45(11):3588-97. PMID:16533041 doi:10.1021/bi0525369
- Pechik I, Madrazo J, Mosesson MW, Hernandez I, Gilliland GL, Medved L. Crystal structure of the complex between thrombin and the central "E" region of fibrin. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2718-23. Epub 2004 Feb 20. PMID:14978285 doi:10.1073/pnas.0303440101
- ↑ Benson MD, Liepnieks J, Uemichi T, Wheeler G, Correa R. Hereditary renal amyloidosis associated with a mutant fibrinogen alpha-chain. Nat Genet. 1993 Mar;3(3):252-5. PMID:8097946 doi:http://dx.doi.org/10.1038/ng0393-252
- ↑ Wang W, Fu Q, Zhou R, Wu W, Ding Q, Hu Y, Wang X, Wang H, Wang Z. Prothrombin Shanghai: hypoprothrombinaemia caused by substitution of Gla29 by Gly. Haemophilia. 2004 Jan;10(1):94-7. PMID:14962227
- ↑ Board PG, Shaw DC. Determination of the amino acid substitution in human prothrombin type 3 (157 Glu leads to Lys) and the localization of a third thrombin cleavage site. Br J Haematol. 1983 Jun;54(2):245-54. PMID:6405779
- ↑ Rabiet MJ, Furie BC, Furie B. Molecular defect of prothrombin Barcelona. Substitution of cysteine for arginine at residue 273. J Biol Chem. 1986 Nov 15;261(32):15045-8. PMID:3771562
- ↑ Miyata T, Morita T, Inomoto T, Kawauchi S, Shirakami A, Iwanaga S. Prothrombin Tokushima, a replacement of arginine-418 by tryptophan that impairs the fibrinogen clotting activity of derived thrombin Tokushima. Biochemistry. 1987 Feb 24;26(4):1117-22. PMID:3567158
- ↑ Inomoto T, Shirakami A, Kawauchi S, Shigekiyo T, Saito S, Miyoshi K, Morita T, Iwanaga S. Prothrombin Tokushima: characterization of dysfunctional thrombin derived from a variant of human prothrombin. Blood. 1987 Feb;69(2):565-9. PMID:3801671
- ↑ Henriksen RA, Mann KG. Identification of the primary structural defect in the dysthrombin thrombin Quick I: substitution of cysteine for arginine-382. Biochemistry. 1988 Dec 27;27(26):9160-5. PMID:3242619
- ↑ Henriksen RA, Mann KG. Substitution of valine for glycine-558 in the congenital dysthrombin thrombin Quick II alters primary substrate specificity. Biochemistry. 1989 Mar 7;28(5):2078-82. PMID:2719946
- ↑ Miyata T, Aruga R, Umeyama H, Bezeaud A, Guillin MC, Iwanaga S. Prothrombin Salakta: substitution of glutamic acid-466 by alanine reduces the fibrinogen clotting activity and the esterase activity. Biochemistry. 1992 Aug 25;31(33):7457-62. PMID:1354985
- ↑ Morishita E, Saito M, Kumabashiri I, Asakura H, Matsuda T, Yamaguchi K. Prothrombin Himi: a compound heterozygote for two dysfunctional prothrombin molecules (Met-337-->Thr and Arg-388-->His). Blood. 1992 Nov 1;80(9):2275-80. PMID:1421398
- ↑ Iwahana H, Yoshimoto K, Shigekiyo T, Shirakami A, Saito S, Itakura M. Detection of a single base substitution of the gene for prothrombin Tokushima. The application of PCR-SSCP for the genetic and molecular analysis of dysprothrombinemia. Int J Hematol. 1992 Feb;55(1):93-100. PMID:1349838
- ↑ James HL, Kim DJ, Zheng DQ, Girolami A. Prothrombin Padua I: incomplete activation due to an amino acid substitution at a factor Xa cleavage site. Blood Coagul Fibrinolysis. 1994 Oct;5(5):841-4. PMID:7865694
- ↑ Degen SJ, McDowell SA, Sparks LM, Scharrer I. Prothrombin Frankfurt: a dysfunctional prothrombin characterized by substitution of Glu-466 by Ala. Thromb Haemost. 1995 Feb;73(2):203-9. PMID:7792730
- ↑ Casas JP, Hingorani AD, Bautista LE, Sharma P. Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. Arch Neurol. 2004 Nov;61(11):1652-61. PMID:15534175 doi:61/11/1652
- ↑ Pihusch R, Buchholz T, Lohse P, Rubsamen H, Rogenhofer N, Hasbargen U, Hiller E, Thaler CJ. Thrombophilic gene mutations and recurrent spontaneous abortion: prothrombin mutation increases the risk in the first trimester. Am J Reprod Immunol. 2001 Aug;46(2):124-31. PMID:11506076
- ↑ Glenn KC, Frost GH, Bergmann JS, Carney DH. Synthetic peptides bind to high-affinity thrombin receptors and modulate thrombin mitogenesis. Pept Res. 1988 Nov-Dec;1(2):65-73. PMID:2856554


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"Little Letter Girls" ~ a series of illustrations inspired by my love for snail mail ☺
Available as postcards here.
Still 3 days to get free shipping in my society6 shop!
Free shipping in my shop until February 10th by clicking this link! Hurry up and go grab something :3
Check out my new project :3 And suggestions for new sadboyz are welcome!Is any of you guys on behance?
Free shipping on everything in my Society6 Shop! Just click the link and the promotion will be activated automatically :3 (Valid until Sept. 16th)
Get 15% off in my Etsy shop during the whole month of July by entering the code: XMAS12 at checkout :3
(Source: wreckthisgirl)
Many thanks, Louis! by anja mulder on Flickr.
Many thanks, Louis! by anja mulder on Flickr.


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Great Escape
Thawing Out on Our 2014 Great Escape Vacation
Another loyal troupe of Y100 listeners join Bear, Charli, and Dan Stone on our 10th annual get away from the frigid Wisconsin winter for a tropical Mexican vacation. Plus, Country stars Thompson Square, Love & Theft, and Brett Eldredge join them for laughs, sunshine and live concerts unlike any other!
Catch the show live from Mexico each morning, and follow the fun in the sun by checking out the pictures and video, courtesy of SunSeekers by Rosie!
Be among the first to learn about Great Escape 2015 and sign up for our preboarding pass email.


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Nylabone Knot
Average rating from 7 reviews.
(4.1 out of 5, based on 7 reviews)
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Reader's Reviews (7)
Strong and safe
posted 6 years ago
Nylabones last for a long time. I feel safe leaving my dog alone with one.
Since my dog was a pup I only gave her Nylabones and Strong rubber toys (kongs). These toys are so much safer than rawhides. they can only get little tiny pieces off. Nothing big enough to choke on. A dog who had had alot of rawhides often wont be interested in the nylabones because they can't demolish them quickly. To keep my dogs interest, I put a little bit of peanut butter in the grooves on the bone
Pros: Strong, durable
Cons: Not every dog likes durable bones
1 of 1 people found this review helpful.
Did you?
A powerful toy for powerful doggies
posted 6 years ago
Big doggies like these and they LAST! Good for many hours of healthy and entertaining gnawing, drooling and chomping. Must taste great to dogs. The ones who like 'em never seem to tire of them.
-- additional:
[updated on 2008-02-22 01:13:38]:
RATE at 5 - excellent product
Pros: For big dogs with a big need to chew
Cons: none that I know of
1 of 1 people found this review helpful.
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Pink is my favorite color these are wonderful.I will recommend a good website fou you: www.9footballshirt.org
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Editor's note: This is part three of a five-part series from Coast Reporter and Transportation Choices (TraC ) concerning commuter cycling on the Sunshine Coast during the annual Bike to Work Week of May 26 to June 1.
Many recreational bike riders make the mistake of treating their bikes the same way they treat other kinds of sports equipment. You use it. You put it away. You come back a few weeks (or even months) later and expect it to perform exactly like it did the last time.
Unfortunately, unlike a baseball glove or a pair of ski boots, bicycles have many moving parts, so they do require some attention to keep them working well.
The good news is, even cycling rookies can perform some very basic maintenance that will help them enjoy a good amount of hassle-free riding (and prevent breakdowns far from home).
Keep your bike clean
When exposed to mud, grime and debris, bicycle parts begin to deteriorate. So, your first line of defence against breakdowns is proper bike hygiene. Bike cleaning means more than just hosing it down occasionally. In fact, water (especially when coming from a high-pressure hose) can cause damage to sensitive bearing systems throughout your bike.
So when washing with water, do so carefully. Most dirty bike components can be cleaned by wiping them carefully with a damp or dry rag. Other components require occasional brushing, buffing and re-lubrication.
Lubricate the moving parts
Once your bike is clean, take a few minutes to lubricate the moving metal parts. You can spot many of these places just by watching your bike in action and seeing where metal parts move against and around each other. Or there are many diagrams and videos available online that can show you exactly which spots to lubricate. Remember to use a lightweight oil especially designed for bikes. Light lubrication is the key, and wipe off excess at the end.
Get your bike tuned regularly
Don't overlook regular maintenance by bike pros. If you're a regular rider, bring your bike in for twice-yearly checkups to ensure that complex, hard-to-evaluate components such as spokes, bearing surfaces, derailleurs and cable systems are inspected and serviced regularly. These bike parts should always be serviced and adjusted by experienced mechanics.
Does your bike need a professional tune-up? In support of Bike to Work Week, both our local bike shops (Spin Cycles in Gibsons and Off the Edge in Sechelt) are offering tune-up specials to participants. Bring in your bike (and registration form or confirmation email) between now and May 25 and save 25 per cent off the regular cost of a tune-up.
For free registration in Bike to Work Week 2014, go to www.biketowork.ca/sunshine-coast and click on 'register'.
© Coast Reporter