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Screening for Inhibitors of Bacterial Capsule Biogenesis E.coli strain UT189 (6)
Over 100 million UTIs occur annually throughout the world, including more than 7 million cases in U.S. adolescents and adults. UTIs in younger children are associated with greater risk of morbidity and mortality than in older children and adults. Antimicrobial resistance among UPEC is on the rise, driving efforts to elucidate vulnerable targets in the molecular pathogenesis of infection. New more ..
BioActive Compound: 1
Related Experiments
Over 100 million UTIs occur annually throughout the world, including more than 7 million cases in U.S. adolescents and adults. UTIs in younger children are associated with greater risk of morbidity and mortality than in older children and adults. Antimicrobial resistance among UPEC is on the rise, driving efforts to elucidate vulnerable targets in the molecular pathogenesis of infection. New insights into the roles of K capsules in UPEC virulence during UTI make capsules an attractive target. Uropathogenic Escherichia coli (UPEC) produces 80% of community-acquired urinary tract infections (UTI). UPEC is also a leading cause of nosocomial UTI, the most prevalent hospital acquired infection. Dissemination of UPEC from the lower urinary tract is associated with morbidity and mortality through infection of the kidneys, bloodstream, and central nervous system. In recent years, the treatment of outpatient and inpatient UTI has been severely compromised by the rising incidence of antibiotic-resistant UPEC.
Investigators have found that encapsulation is an important UPEC virulence factor. The K1 capsule type is closely associated with pathogenic isolates; not only is it the leading type in UTI, but it also accounts for much of the extra-urinary tract complications. Animals studies of E. coli K1 sepsis demonstrated that injection of K1 capsule degrading enzyme abrogates infection. However, the enzyme treatment is immunogenic; accordingly, chemical inhibition may prove to be a superior approach.
Of the different K types, the Group 2 and Group 3 capsules are most prevalent among UPEC isolates, with K1 and K5 being leading types. Although the capsules have different compositions, they are synthesized, assembled, and exported by functionally homologous factors, leading us to hypothesize that we can develop small molecular inhibitors of K-type encapsulation that target the most medically important K types. Furthermore, the medically important infectious agents Campylobacter jejuni, Hemophilus influenzae, Neisseria meningitides, and Salmonella typhimurium among others, use these homologues in the biogenesis of their capsules. By exploiting the properties of a K-type specific phage, we performed a small scale high-throughput screen of >2,100 molecules from the NCI that uncovered several promising inhibitors of K1 and K5 encapsulation. This assay will identify a larger number of inhibitors with different mechanisms of action from which we may determine the optimal targets for capsule biogenesis inhibition and develop analogues with pharmacologically optimized properties.
Chemical modulators of K1 encapsulation might represent a new avenue to combat the catastrophic effects K1 diseases. To this end, this team has successfully developed a 1536-well high-throughput primary screen suitable for the discovery of novel capsule biogenesis inhibitors. This 96-well format confirmatory-screen for dose-response confirmation of the primary screen hits is detailed below.
This screen recapitulated the primary screen in the culture tube format. Compounds were received in powder form and resuspended in DMSO to create 10 mM storage stocks . One hundred microliters of each compound was taken and diluted two-fold sequentially to 0.078 mM in PCR strip tubes to create working stocks. Compounds were kept frozen in sealed vials or PCR tubes at -20C (protected from light). Overnight cultures of UTI89 (K1) and kpsM mutant were grown in LB from a colony on a plate (from freezer stock). The cultures were then diluted 1:100 into a clean and sterile 96-well flat bottom tray (99 ml per well). Compounds were then added to each well (1 ml per well for final concentrations ranging from 100 uM to 0.78 uM (for indicated wells, DMSO only was diluted to a final concentration of 1%). Each compound concentration was tested in duplicate. Each plate contained controls for growth of UTI89 with and without phage as well as kpsM mutant resistant to phage lysis. On a LB plate, UTI89 and kpsM were tested for K1F phage sensitivity to confirm lysis of UTI89 by phage preparation. The plate was then sealed with tape and placed in a shaker at 37C. After incubating the plate at 37C with shaking for 1.25 hrs, an absorbance reading (OD600) of the plate was taken and indicated wells were infected with 5 microliters of K1F phage (from freshly cleared lysate). The plate was returned to the shaker and a second growth reading was taken 3 hrs post infection to determine lysis.
Inhibition of phage lysis was calculated relative to the mean of the cell control (minus phage). Data are graphed as the mean A600 at 3 hrs p.i. +/- SD of two wells normalized to the average of UTI89 + DMSO + no phage (3 hrs p.i.). Values are expressed as percentages and graphed as % Inhibition of Phage Lysis (which is equivalent to cell viability). Inhibition of phage lysis was determined at each of 8 tested concentrations ranging from 100 uM to 0.78 uM. IC50 values were calculated only for compounds showing >=50% inhibition of phage lysis using XLFit.
Outcome: Compounds that showed inhibition of phage lysis of >= 50% at any point on the dose response curve were considered Active. Compounds giving discrepant results between the replicates are labaled as inconclusive.
Score: In this secondary dose response screen using synthesized compounds, active compounds were scored on a scale of 81-100 based on the relative IC50 values. Compounds that were not confirmed as active in the dose response screen were given the score 0. Primary screen data is scored on a scale of 0-40, confirmatory data is ranked from 41-100.
Result Definitions
* Activity Concentration. ** Test Concentration.
Additional Information
Grant Number: 1 R03 MH090791-01
Data Table (Concise)


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Plugged In is the entertainment guide your family needs to make family appropriate decisions through movie reviews, book reviews, TV reviews, and more.To learn more on our vision and passion for helping families, check out our about us page.
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Today was a good day.
Facebook was lit up with blue in support of World Autism Awareness Day. Major buildings from all over the globe shined a glorious blue light putting emphasis on a disorder that has so shaped my life. Autism.
Autism Awareness Day in my family looked a lot like another day. My lovely wife wore her Autism earrings, dressed the boys in blue shirts adorned with puzzle pieces, I chatted with The Pier Center for Autism's Board President Josh Cobbs 4 or 5 times (on and off-air), educational and daycare staff made it their mission to help my son, Trey (9 years old) , in every way possible. Beau (his 7 year old brother) was by Trey's side all night long and he told me he really wants Trey to live with him when he gets older so he can keep an eye on how to buy cialis in canada him. Talk about heavy thoughts from a first grader on a Tuesday morning. Three people asked me how I thought Trey "got Autism". My response: "I have no clue".
This may come as a shocker to you – in our family - we are well aware of Autism. We see it every waking minute. It weighs on our minds daily. Many questions remained unanswered. Some days are better than others. Some days aren't. You learn to adapt. You learn to pray. You learn to hope.
You can't preach understanding.
We knew nothing about Autism Spectrum Disorders 8 years ago. We viewed "Rain Man". That was it. The first thing we did when we had concerns was to hop on WebMD. That's a night I never want to order viagra cheap relieve. Some of what we read that night came true. Trey is 9 years old. He is non-verbal. He still wears pull-ups. He "flaps" his arms when he gets overly excited. He's different from his peers.
In other ways, WebMD could not have been more wrong for us. Trey is VERY LOVING. His mind is always working in overdrive. He has great eye contact with us. He can melt your heart with a single glance and giggle.
You just never know.
Since Trey's official diagnosis at the age of 3, it seems as though society "gets it more". The level of awareness and knowledge base has increased tremendously. Maybe it's because it is how to get cialis no prescription more diagnosed, far more radio/tv stories about the subject, Facebook and Twitter posts, print articles and levitra canada the like….
I'd like to hope it's because more people meet kiddos like my son. More hearts have been melted by a giggle and a grin.
I appreciate every single question I get about Autism. It means people are trying. I love it when a parent like my buddy Josh from The Pier Center starts an organization that betters the life of online viagra drugs those like Trey. It always better to have dreams and an action plan.
Awareness is a great start. Next year, let's have World Autism Action Day!
Tony Michaels
KSUX Program Director / Pier Center for Autism Board member / Autism Dad / Dreamer / Fan of Action
Sioux City, IA
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2012 Grammy Winners
See all the winners from the 54th Grammy Awards.
Adele Top Winner With 6 Grammys
Adele and Foo Fighters were big winners at the 2012 Grammy Awards. Find out what else happened.
The Beach Boys To 'Do It Again' At The Grammys
The Beach Boys — Brian Wilson, Mike Love, Al Jardine, Bruce Johnston and David Marks — will reunite on the Grammy stage on Sunday, performing live together for the first time in more than two decades.
54th Annual Grammy Awards To Feature First Dance Music Segment
Grammy show producer Ken Ehrlich had considered putting dancing/electronica music into the ceremony in the past, but could never quite figure out how to incorporate the high-energy club feel in front of a sometimes staid audience.
Watch GRAMMY Artist Performances From Live On Letterman
Katy Perry, Adele, Coldplay, Wilco and other 2012 Grammy nominees perform Live on Letterman.
Download The Complete List Of 2012 Grammy Nominees Now!
Here are the nominations for the 2012 Grammy Awards, to air on CBS Sunday, February 12.
Bruce Springsteen And The E Street Band Will Play At Grammys
Bruce Springsteen and the E Street Band will play the 54th Annual Grammy Awards, February 12 on CBS.
Katy Perry To Make Her First Post-Split Appearance At The Grammy Awards
Katy Perry is expected to perform at the 54th Annual Grammy Awards on Feb. 12, marking the singer's first public appearance since her highly publicized split from Russell Brand.
Adele To Sing At Grammy Awards, 1st Performance Since Vocal Cord Surgery
Grammy nominee Adele will make her much-anticipated return to the stage for the 54th Annual Grammy Awards, nearly five months since having surgery on her vocal cords.
2012 GRAMMY Nominees Album To Be Released January 24
The 2012 GRAMMY Nominees album will be released digitally and in stores January 24, 2012. The album features 22 hits from some of the GRAMMYs' most popular nominees.
LL Cool J To Host 54th Annual Grammy Awards On CBS
The Recording Academy announced Wednesday that LL Cool J is set to host the 54th Annual Grammy Awards on Feb. 12. LL Cool J, who has hosted "The Grammy Nominations Concert Live!" since its inception in 2008, will be the first official host of the show in seven years.
2012 Grammy Nominees
Here are the nominations for the 2012 Grammy Awards, to air on CBS Sunday, February 12.


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Ministry-Based Programs
The Mobile MA in Christian Leadership enables you to stay in your current ministry while DTS partners with local church and parachurch ministries to offer a seminary degree. DTS tailored the program to help you better love and serve your people. You'll learn alongside other like-minded leaders working for the good of your community and city.
*Mobile sites currently under construction.
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What You'll Learn
From the ministry to the marketplace, the MACL gives you a strong biblical foundation and the leadership tools to adapt to diverse situations.
|Area of Study
|Biblical Exposition (BE)
|Theological Studies (ST)
|Vision, Communication, and Leadership (PM, CE)
|Ministry Internship (SL)
Frequently Asked Questions
- What is the Master of Arts in Christian Leadership (MACL)?
- The Master of Arts in Christian Leadership (MACL) degree is designed to provide graduate-level biblical and theological education to prepare students for organizational leadership roles in a wide variety of ministry settings. The training prepares students to assume leadership positions in church, parachurch, missions, and marketplace contexts.
- Is the MACL the right degree for me?
- It depends. If you anticipate preaching and teaching to represent the bulk of your ministry, the Master of Theology degree is probably a better fit. However, if you anticipate serving in a variety of leadership roles where teaching and preaching are not primary, then the MACL is right for you.
- Do I need to move to Dallas to earn the mobile MACL?
- No. The beauty of the mobile MACL is that DTS comes to you. It's possible that you'll only need to come to Dallas four times for a total of four weeks during the entire degree. See the How it Works section above for more information.
- What are DTS courses like?
Mobile MACL courses are offered in a number of formats:
- Live-On Site: DTS offers some courses in person wherever there is a cohort. Although the number of meeting times for each course may vary depending on the course, a DTS professor leads the instruction and in some cases partners with a local church pastor(s) to bring his ministry and leadership expertise into the educational process.
- Online/Video Conferencing: The flexibility of the mobile MACL comes from students' opportunity to take online courses. Taught and overseen by fully credentialed DTS faculty, these courses allow students to merge seminary into busy lives. In some courses students may participate in video conferencing or other real-time components where the professor in Dallas teaches and interacts with the cohort using high definition technology.
- Live-Dallas: MACL students are required to complete at least 21 hours of the degree at a campus approved to offer the leadership degree. In order to minimize time away from your ministry, the Seminary offers special week-long courses in Dallas at four different times during the degree program. MACL students complete work before coming to Dallas, fulfill the residency requirements for courses in one week at Dallas, and complete online work after returning home. In the end, you will spend a total of four weeks in Dallas (one week per calendar year) over the course of the program. The final week of residency is adjacent to graduation, thus minimizing travel time.
- Do I work with other students or only by myself?
You work with other students in a variety of ways. For online courses, you may be grouped with other DTS students or others in your cohort. You'll get to know these student by reading their autobiographies and interacting with them on questions relevant to the course.
For live courses, you'll be in an actual classroom with your cohort and a DTS professor. In Dallas, you and your cohort will have class with other cohorts from around the country. This will give you an opportunity to network with other students in similar ministry situations.
- Can I join a cohort after it has begun?
- Yes. The Advising Center can help determine the best way to get you plugged into the cohort in your city.
- Can I work full-time and complete the mobile MACL?
- Absolutely. The MACL was designed specifically for people working extensively in ministry situations. Although challenging, students tell us that taking two courses per semester and working full-time is very manageable.
- Do I need to be serving in ministry to do the mobile MACL?
- Although the MACL was designed for those already serving in ministry, anyone who meets the admission requirements for the Seminary can pursue the degree.
- What is the ministry residency?
- MACL students have the option of earning eleven credit hours toward their degree by serving in their current ministry. We call this the ministry residency. DTS believes that preparation for ministry takes place both in the classroom and in the field of service. It is vital to link theory and practice. Instead of learning only in the isolation of the classroom, DTS supports learning happening within the community of faith as you serve in a ministry context and reflect on that experience.
- Can the ministry residency be done in a business setting?
- Yes. Students who have leadership responsibilities in a business context can participate in the ministry residency. The Spiritual Formation and Leadership office can provide more information about that.
- How long will it take me to finish the degree?
- The Mobile MACL is designed to be completed by a cohort in four years by taking one or two courses per semester. Check out the How it Works section above.
- How will my church be involved?
Your church can be involved in a variety of ways. For example, students work with their churches to design, implement, and evaluate the ministry residency component of the degree.
Some churches may work with professors in hosting live course components for online classes, such as discussions.
Some churches offer financial assistance to staff or churches members who desire to pursue the Mobile MACL.
- How much does the Mobile MACL cost?
- The average cost of the Mobile MACL is about $2500 per semester for eleven semesters (this includes fall, spring, and summer terms).
- What is Spiritual Formation, and why do I have to be a part of it?
- Spiritual Formation is a program that provides a relational context and biblical curriculum designed to help leaders explore key topics related to the Spirit's work in our lives and the lives of those to whom we minister. Our heart is that through the SF process, MACL students will grow in their appreciation for God's authorship in their life stories and the necessity for Christian community in every aspect of our lives. The MACL exists to equip and prepare leaders. The work done through your time in Spiritual Formation is foundational to the concept of service through leadership for the body of Christ.


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This conversation is closed.
To elicit action via this forum from either a consortium or individuals to place open letters in major media regarding respective subjects
The letters ought to be directed to... and demand that...
A) Accurate unbiased representative government by civil funding only.
B) True science based whole health postured care system uninfluenced by money via profit systems.
C) Mission statement adherence within the financial industry that center on noble fair and equitable credo with real penalties.
D) Media reportage unencumbered by connection to industry or otherwise biased in anyway so committed to being a forth estate.
E) Food industry not in anyway disconnected with health science, at it's mission to promote well being not profit on ill health.
F) Education take a non industrial age template to children/adults of the 21st century and formulate a truly healthy environment in efforts toward the goal of problem solving for health welfare and thriving future generations.
G) Entertainment industry be civilly culpable and so aware not just to bottom line reactive sales with reptilian responsive base triggering via violent imagery.
H) Oil and mineral industries to comply with accepted peer reviewed environment science regarding impact on basic human survival and use equitable policies on retrieval of these minerals. And value based responsible economics included in these equations.
it would be a next move to create a social network page for collaboration, action tasking and further discussions.
Apr 25 2013: It upsets me when responses are from those who when researched, seem bent on dragging conversations into confrontations with little in the way of reality or construct from any reasonable viewpoint. SO PLEASE if you cannot or will not be a civil responder with only constructive criticism and with a thoughtful reach toward "the golden rule" stay away from anything I write. I will from here forward ignore your simple flaming effort and the rule is.. treat others how you would like to be treated in case you missed that day in school. Thank you.
edward long
Apr 25 2013: Kudos on your composition, language wise! Machiavelli is turning in his grave. In a world ruled by craftiness, duplicity, and expediency your suggestion sparkles with optimism, simplicity and altruism. What a clash! Best wishes.
- +1
Apr 25 2013: ye who enlightens my weary heart a great big thanksApr 25 2013: Personally, from my perspective, he comes off naive as heck. The media makes money via sensationalism and war.
edward long
Apr 25 2013: Well Jim, I think Mr.Cogswell is advocating for improvements to the zeitgeist. If I am right he seems to have nailed most of the improvements needed. In a dark, pessimistic world like ours optimism is often mistaken for naivete.
- +1
Apr 25 2013: Every election is time for change---lol--in 200 years its simply more of the same. But hey, his ideas of change are the same as the last 200 years.
Tell us of one form of gov that is not fully corrupt or the super majority of the media that does not hide most all the gov's deceptions, with one rule for the rich and connected and another for those not rich or connected. It has always been and will always be. Gov's pit the haves against the have nots or are you and he so blind that you cannot see?
Honest people and dishonest people cannot work together, because each looks down on the other. All of congress takes bribes and or they refuse to stop the bribe taking, making them all guilty. That's been going on for over 200 years, so yes, you both are naive.Apr 26 2013: Edward,
I agree with that and would like to add that at times also idealism happens to be mistaken for either naivety, vigilantism or mysticism.Apr 26 2013: Jim,
That's true, they do make money and personally I see nothing wrong about that under one condition - that sensations they present to the consumers at large are reality and research-based, not interest based, and providing information. When this information is sensational (e.g. cure for AIDS, cure for cancer etc.) - even better. Everybody needs sensation and entertainment.
"Honest people and dishonest people cannot work together, because each looks down on the other. All of congress takes bribes and or they refuse to stop the bribe taking, making them all guilty."
Great power corrupts greatly. But not everybody... And I'm not sure I fully agree with the clear distinction that you're making - honest people vs. dishonest people. Sometimes it's lack of knowledge, awareness or willpower that lead to infringements or escalation of greed.
Apr 26 2013: Why would one people own 96% of the WORLDS media?
"The pen is mightier than the sword."
In any war, you have to win the hearts and minds of the people.
Believe all the propaganda you want, it doesn't make it so.Apr 26 2013: ""The pen is mightier than the sword."
In any war, you have to win the hearts and minds of the people.
Believe all the propaganda you want, it doesn't make it so."
...but actions speak louder than words and the devil lurks in the details. In peace, amen.Apr 27 2013: so sure a FB page and certainly some other than promoted interest, busy as I am it will either do nothing as my detractors seem to want or once I get time to spend time it might be a good thing, in any event its something, weak critique aside.
www.facebook.com/OpenLettersToAmericanInstitutionApr 26 2013: Naturally.. points taken, and I am absolutely drawn to what the tedsters accomplish and need not differentiate if higher disconnect indeed fits. Directly I am ill effected by a couple of negative responses and the case made for it here.
I would not have marveled at teds were they so inclusive so come to ted talks as an important place for me in this new information age and the transitions to it.
As I have allowed time its place and tonic I first and most importantly recognize how the dialogue has swerved away from any semblance of the topic. And i am intent on wrapping up the focus on whether or not tearing down ideas or otherwise reflecting nothing close to the spirit of the talks I have seen. As it becomes apparent again my effort is toward the vision I have interpreted ted discussion board affords. All while honoring your interjections I do not think this particular back and forth, you and I, is on beam as I see it. While you feel certainly clear about how this forum works best and it's limits it may help me not to extend that perception to my understanding. People laughed and mocked me on this idea and your posture I have navigated to a point where while points taken I suspect we do not share the same perspective. Good day sir.
Comment deletedApr 26 2013: Thank you Fritzie for great insights taken in tonight for a time to digest and readdress tomorrow.
As I do intend to do this I cannot resist first recognizing that in an "action science" sense it would be unfortunate. There seems to be more intelligence compressed here @ Ted than most other places so as in an open forum it is attractive. It would however be a shame if indeed it turns out to be simply a spot where we all spin in place, one gargantuan ego playing in league with another of similar size bantering on infinitely blah blah blah and so on.
A very goodnight!.
Fritzie -
Apr 26 2013: I don't think it is at all "a spot where we all spin in place." Many TEDsters are actively engaged in projects that are meaningful to them. What they do not do, necessarily, is to drop those meaningful efforts when another option and its champion come to town.
- +1
This is another idea that is worth considering from an angle other than your specific interest. If people don't jump to follow any particular leader, you cannot logically conclude they are not engaged in meaningful projects and are just bantering infinitely. They may simply consider their projects a higher priority for their efforts than your project is to them.Apr 25 2013: Philip, I think you might get more satisfying response if you clarify what you are looking for. Are you asking for people to say, Sure, I'll write letters to major media demanding your eight demands here? And then to add a few more demands to your list? (And not to respond to the thread if they question the viability of your project?)
Or are you looking for feedback or discussion of any of the ideas themselves?
Or are you asking people whether this forum is a good place to organize a network of supporters for the letter writing campaign you envision?
For example, I didn't interpret Pat's comment as not being civil. It was just too terse, obviously, for you to understand his position.
Apr 26 2013: First Fritzie great and good to see your interest and efforts to help. Yes to all of your questions in fact emphatically yes, dissection discussion and perspective as well. But there is obviously terse response vs a civil discourse. I find the fact Pat responds with nothing but a contrary statement and looks to me to engage him without making any initial point is high riding. In fact having admittedly looked at his arguments, and they seem exclusively that, over posts I decided his value is not appreciated in my heart I know this. This idea is my discussion and there are other open letters on Ted so it is not that hard a concept to follow. And so some here have baseless arguments it has been noted and I refuse to engage. I am optimistic and fail to see merit in such overall negativity. I have two respondents who beg an argument based on what patterns I see with other posts. This is not my problem it is decidedly a problem at Ted. It is no more than flaming and it troubles me. But as I said optimism carries me when folks laugh out loud at me or try to drag me to their shallow depths of conflict for its sake only it does not work. I am happy and will probably remain this way. Who is better off?
Apr 26 2013: I still fear the way you have posed your question is not the most fruitful.
One question you might ask (independent of whether people agree in principle with your demands) is for people to give you feedback on whether presenting a list of demands like this to media outlets is likely to get media outlets' attention in a way that is productive to your agenda. If they think this approach is not the best to advance your agenda, what alternative would they expect to be more effective?
Another question is what is the best way to gather letter writers for a letter writing campaign. I would have thought going to your social media channels, starting with people you know and who you know agree with your positions would be higher probability than posting to a discussion site.
On that point, one thing I have noticed in my year of participation in TED Conversations is that it does not feel like a group of people waiting for a leader to come in and lead them in a project. For one, people seem to me quite independent minded, but even without looking for reasons, I have seen multiple times when someone has come in with a proposal looking for supporters here for an initiative, or to steer a collective effort here unrelated to the site itself, and I have never seen people rally behind the proposal in the sense of saying something like Count me in.
I am not saying there cannot be a first time, but I have a feeling this is not your most promising hunting ground for this project.Apr 25 2013: Are you trying to make us all rotfloao, because its working.
There is no such thing as care for the people or justice in America. Just look around.
Apr 25 2013: your simple thanks is proof positive enough for me, cynicism will get you nowhere change your circumstance.Apr 25 2013: That won't work


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In fact, during your visit to West Palm Beach Hyundai serving Palm Beach, Greenacres City, Delray Beach and Palm Beach Gardens drivers, our team is available to arrange more than a thrilling test drive. At your leisure, we're happy to discuss feasible Hyundai financing opportunities, to help you get started down the path to ownership, today.
Dealer is not responsible for pricing errors. Prices good for three days from date publication. Pictures can be for illustrations purposes. All vehicles subject to prior sale. New car prices include applicable manufacturer incentives & manufacturer rebates in lieu of special financing. Plus tax, title, tag and dealer fees. Used vehicles prices plus tax, title, tag and dealer fees. All offers with approved credit. All prices, specifications and availability subject to change without notice. See dealer for complete details.


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(05/30/06) As many of you may have noticed YourPimpSpace has changed A LOT! In this update there has been 10,000 thats right 10,000 MySpace Graphics for your to choose from! If that wasn't enough we also added 5,000 MySpace Layouts! You can now have a different layout everyday if you wanted!
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Wedding Ceremony Music near clarksville,mi
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Overneath Weddings38 Reviews
We Make What Moves You
Kalamazoo, MI | 269-903-3103
Providing Ceremony Musicians, Customized Ceremony Music, Cocktail Hour Musicians, Live Bands, DJs, Photography and Videography: we are Overneath...(more)
Mike Davis Trio - Ceremony, Cocktail, and Reception26 Reviews
Two Trios in One (Classical & Jazz)
Traverse City, MI | 231-357-4870
The Mike Davis Trio, one of the most popular music trios in Northern Michigan, is really two trios in one. The music trio is comprised of three...(more)
Soprano Elizabeth Cameron11 Reviews
Servicing Southwest & Northern Michigan
Kalamazoo, MI | 917-334-5234
A live performance of the perfect song is the ultimate way to express the love in your hearts. Soprano Elizabeth Cameron will help you shape your...(more)
Robert McCloy - Musician112 Reviews
Your Requests Are My Business
Mason, MI | 517-203-4477
Music for Ceremonies, receptions, rehearsal dinners, corporate & private events. I'm thrilled and overjoyed by SCOTUS ruling for marriage...(more)


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Experience the power of a touch. Slim and light, the Nokia 6131 phone is encased in a layer of soft-touch paint that feels great in your hand. Flip it open with the unique one-touch push-to-open design for comfortable one-hand messaging, dialing and answering calls Inside, the Nokia 6131 phone comes with all the features you want, including a brilliant 16.7-million "true color" main display and 262,144-color outer display, ideal for use with the 1.3-megapixel camera. Enjoy the full music experience with MP3 player and FM radio with Visual Radio technology.
- Nokia 6131 Unlocked (Black Color)& H700 black
- Travel Charger (EU plug)
- USA Adapter
- Original Stereo Headset
- English Manuals
Customer Reviews
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The Community of Disc Golfers and About All Things Disc Golf
I was watching ESPN tonight and was talking to my buddy who isn't really into disc golf. And i told him that i think DG is going to really grow in the next five years and come mainstream. He denied it saying there are other growing sports that would come first but couldn't really name any specific ones.
Any thoughts on the growth of the sport?
Views: 262
My opinion is that the PDGA should team with the PGA on a few of these national televised tournaments. By using portable baskets a regular 18 hole ball golf course could be turned into a 36 hole disc golf course. The cameras and staging would already be set-up. Of course the main event would be the ball golf, but I equate it to having "warm-up" bands at a rock concert. This would be the most efficient and economical way to televise the sport. If it does not become popular, then they can go to plan B.
That's what I thought when I read that statement. It's been 5 years away for 20 years.
Those snobby fucks at the PGA would never let us discers near them. You have to learn how to hold a teacup correct. But the idea of doing that is fantastic. The sports on a good pace of growth. We need to stay passionate and keep promoting in new ways.
Since building new DG courses on private land in Southern California would cost millions of dollars, piggy backing onto existing ball golf courses has been the new fad out here. Verdugo Hills is the latest course to be a dual use course. Ball golfers and discers playing at the same time. So far it has worked out really well.
We also have the Van Buren dual use course in Riverside county and the Goat Hill course in San Diego County. Goat Hill has a tourney coming up bill as the longest (Length) disc golf tourney in the world. The course is so long you have to se a golf cart.
I'd rather we had seperate use courses, but the dual use courses are not bad. Verdugo Hills in particular makes really good use of the tree'd area along side the ball golf fairways. There is some very interesting Mando's as well to keep everyone safe.
that sounds rad, are some fairways shared? and some running along side? who yields to who? pay how much to play? tee-times? i haven't heard of this before
Wow that sounds very cool. Didnt know this concept of sharing courses was out there. I would like to see how this idea spreads
Verdugo Hills is a pitch n putt par 3 with the longest hole being 140 yards. Fairways and tees are completely shared. Ball golfers are usually pretty good about letting us play through. It's kinda the ideal length for a DG course, IMO.
I thought they only did that in Florida!!! :0
I cannot WAIT to win the lottery and build a 27 hole DG Course on an existing ball golf course. My day will come!!!!!!!!!!!!!
There are a surprising number of shared courses around the country---4 that I can think of in South Carolina alone.
However, there are drawbacks to the concept. I can't imagine it ever being more than an exotic alternative.
© 2015 Created by Terry "the Pirate" Calhoun.


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Home > Bath & Spa > Bathroom Storage & Decor > Teak Shower Stools > Mini Teak Corner Shower Bench with Shelf
Mini Teak Corner Shower Bench with Shelf
Ideal for virtually every shower - large or small.
Teak is prized for its rot and mildew resistance making it an ideal wood for use inside the shower.
The Mini Corner Shower Bench with Shelf can be used inside or outside of the shower and is perfect for a support when shaving or even a place to keep your shampoo and body wash.
This pre-assembled corner bench is made entirely of teak with marine-grade stainless steel fasteners. As with all of these products, the mini corner bench is handcrafted of the finest quality teak and features a hand sanded finish that will withstand every day use in the shower. Whether you select Burmese Teak or Plantation Teak, this piece will bring beauty to any bathroom designed.
Wood Offering Descriptions:
- Burmese Teak: Our premium Teak which is pure heartwood from mature Teak trees grown in the Indonesia/South East Asia region. Heartwood Teak provides an elegant piece with unique grain patterns and a beautiful rich color giving any area an immediate WOW factor. The high silica content in teak makes it an ideal wood to use when a slip resistant surface is needed and the natural oil makes the wood resistant to mold and mildew.
- Plantation Teak: Our FSC certified Plantation Teak comes from trees harvested from an actual plantation of younger Teak trees. Since we only use the heartwood of the tree, it has all the same qualities of old growth Burmese Teak but it is a little lighter in color
Mini Teak Corner Shower Bench with Shelf
Mini Teak Corner Shower Bench with Shelf
Mini Teak Corner Shower Bench with Shelf
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Mini Teak Corner Shower Bench with Shelf
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Residential programs for victims of sex trafficking are sorely lacking in Virginia, according to a national survey and local officials.
A national survey of residential programs for victims of sex trafficking was recently undertaken by the Criminal Justice Information Authority of Illinois. Results of the national report, published in October, show that out of the 682 residential beds dedicated to victims of sex trafficking in 33 residential programs nationwide, only six of those beds are available in Washington, D.C., and none are in Virginia.
According to the authority, domestic sex trafficking is a violation of human rights and considered to be a form of modern day slavery. It is recognized as a growing issue in the U.S.; however, the full extent of trafficking remains unknown. Traffickers and victims often avoid detection since much of the criminal activity is hidden and victims rarely seek help or report their situation to police.
What constitutes trafficking is also often misunderstood.
Trafficking victims do not have to be foreign-born or transported across borders; in fact, many are born in the U.S. and are never moved from their recruitment city. Victims of trafficking often suffer from serious physical and psychological problems.
"Sex trafficking victims have very specific physical and psychological needs," said Chris Davies, director of counseling services for the Fairfax County Department of Family Services' Office for Women & Domestic and Sexual Violence Services. "Many times they do not see themselves as victims because the level of their manipulation is so high." According to Davies, historically there have always been a limited number of shelters and services available for these victims, and even fewer with the capacity to appropriately treat the severity of sex trafficking victims' problems.
"There is a shortage of shelter space throughout the U.S. and especially in Virginia. What often happens is that sex trafficking victims are sent to domestic abuse shelters, but the needs of domestic violence survivors are very different than those of sex trafficking victims, and they are not always compatible."
In addition, shelter space strictly for domestic abuse survivors is also at a premium in Fairfax County.
Every month, Fairfax County Police receive nearly 1,000 domestic calls for service and on average make more than 160 related arrests, according to a 2013 annual report prepared for the Fairfax County Board of Supervisors by the Domestic Violence Prevention, Policy & Coordinating Council.
According to the 20-page report, domestic violence hotlines countywide receive almost 260 calls each month. Also on average each month, 65 domestic violence victims request family abuse protective orders, and 14 families escape to emergency domestic violence shelters.
Sex trafficking is also on the rise in Fairfax County, creating an even greater demand for dedicated shelter space. Since 2010, the commonwealth has obtained 50 human trafficking-related prosecutions and identified 375 victims. The U.S. Attorney's Office for the Eastern District of Virginia in Alexandria has also prosecuted 24 federal cases against 50 defendants since 2011.
In October, The Fairfax County Police Department received a $1 million grant from the U.S. Dept. of Justice to be able to better battle the growing trend of human trafficking in the county. Half the award, $500,000, will enable the police department to have one full-time detective and one crime analyst dedicated to the issue.
The other half of the award went to the Washington, D.C.-based nonprofit Polaris Project, which provides services to human trafficking victims. Polaris is the organization outlined by the Illinois Criminal Justice Information Authority national survey as providing six residential beds for the entire Washington, D.C., metropolitan area.
"Polaris does a great job," said Davies, "But they generally serve a different population in D.C. We could really use a sex-trafficking victim residential program right here in Northern Virginia."


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Trade between countries allows people to purchase goods or services they desire, or sell goods and services they create.
But do open borders allowing the free flow of goods, services, ideas, and information between provinces and between countries improve our economies and standard of living? What are the outcomes of trade? What are the benefits, if any? Should we place limits on trade?


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Own a piece of history for your wall! This incredible print gives you a large-scale reproduction of a historic advertising poster from the early years of competitive racing. From Brett Horton's vast collection of vintage cycling posters and photography, this rare piece (original is worth thousands of dollars) features one of the earliest examples of a sponsored racer - France's legendary champion Andre Leducq, winner of the 1930 and 1932 Tour de France, and, as indicated here, #1 Frenchman in the 1927 Tour. With a breathtaking scene of Leducq taking on an endless Alpine climb, a vintage photographic image of Leducq in his prime, and the whimsical use of Thomann's happy elephants, this is both a historic work of vintage cycling art, and a beautiful piece for the wall of home or office! Reproduced faithfully to the original, and printed on heavy gallery-quality paper stock, this is perfect for framing, and will become the centerpiece of your cycling collection.
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Gallery: Team Tidewater's Solar Decathlon Unit 6 is an Efficient Protot...
The team took inspiration for its design from the arts and crafts-style homes found throughout the center-city neighborhoods of Norfolk, Virginia. Craftsman style lines, windows and decor put this home in a more traditional light, which could likely appeal to a wide audience – especially those living in historic neighborhoods. But after you get past the aesthetics, there's nothing about this home that is traditional. Passive solar design plays a starring role with south facing windows that take in the sun during the winter, and large overhangs and shades that block it out in the summer. A retractable window in the living room transforms the space into an open-air porch, and a pocket window into the kitchen encourages natural ventilation.
Modular construction, allows Team Tidewater to pick up each room for easy transport up to DC, and a high performance facade will maintain the thermal balance. High performance windows regulate the heat and the cold, while smaller windows on the north side allow daylighting to permeate the home. The mechanical core with the inverters, solar hot water tanks, and other systems are housed in a small room off to the west of the house next to the porch. Window and door sensors provide security information and tell the HVAC system how to operate if the home is open or closed.
Unit 6 is designed as a prototype for a much larger, 6-unit multi-family housing project. These buildings have six units stacked on either side of a central circulation and mechanical core. Each unit has a deep porch, to provide shade to the living room and encourage natural ventilation, while other windows are shaded from the sun. Just like in Unit 6, the mechanical core is stored off to the side of the house and shared with the other apartments as a way to increase the affordability. Team Tidewater has been researching systems and performance for two, six-pack buildings that are being prepared for construction in Norfolk.


text: Front View larger Pro.Fit miniGRIP Universal holder for small portable devices Item #: 042MI200BG 4 Reviews This item is no longer available. Original Price: $24.99 Shop all Device Holders Need help? 1.888.955.6000 Email Chat Ask an expert advisor No pressure, no commission — just lots of good advice from our highly trained staff. Overview Reviews Details Articles & Videos by Zak Billmeier Having a hard time finding a way to mount a small device like an iPod mini, portable MP3 player, or cell phone in your car? Pro.Fit's miniGrip features adjustable sliding clamps designed to secure smaller portable devices. The clamps can grip your device either horizontally or vertically, depending on where your device's inputs and outputs are located. The adjustable supports on the bottom of the mount accommodate several types of device power plugs. The miniGrip fits perfectly on a Pro.Fit universal or vehicle-specific mount. Enter your vehicle information to see if a vehicle-specific mount is available for your car, truck, or SUV. You can also install the miniGrip using the included adhesive backing. Product Highlights:universal holder for iPod, MP3 players, cell phones, and other portable devicessliding clamp holds your portable device in placesupport tabs adjust to accommodate several types of power plugsvertical or horizontal mountinguniversal or vehicle-specific mount also recommended (sold separately)secures devices 1-3/4"-3-1/4" wide and up to 4" tallwarranty: 1 yearOur 60-day money-back guarantee Pro.Fit miniGRIP Reviews Average Customer Review: 4 reviews Review this product Submit a review and then enter to win a $350 rewards card Filter by rating: 5 Star: (0) 4 Star: (0) 3 Star: (0) 2 Star: (0) 1 Star: (0) Review this product: Thanks for taking the time to share your experiences about this product. Please be sure to focus your comments on the product itself. Read our Review Guidelines for more information. Review title * Email Your email won't be visible. Please use the email address that is associated with your order. Display name (e.g., JohnD) Your review will be signed using the display name and location * Your location (e.g., Charlottesville, VA) * Your rating Click on a star to rate the overall product on a scale of 1-5 1500 characters left * Your review Attach a YouTube Review Crutchfield Video Review Guidelines Only submit videos that you made or are authorized to use. Do not submit videos that contain music, video or visuals that are copyrighted and belong to someone else. Please see our Review Guidelines for more information. Enter the URL of your YouTube™ video review or product demonstration. e.g., "http://www.youtube.com/v/o79TWHh598U" 500 characters left Pros 500 characters left Cons * Agree to Terms By checking this box you agree your review becomes the property of Crutchfield, that you are over 18 years of age, that you own or have owned this product, and that you are located within the United States or its territories. Please see our Review Guidelines for more information. We reserve the right (but are not obligated to) review all submissions and edit or remove any review in any manner which we deem necessary. Your review should be posted within seven days. Pro.Fit miniGRIP Written By Kay, Folsom, CA on Tuesday, June 28, 2011 Crutchfield Customer Review (What's this?) Works perfectly for my BlackBerry 9700, 4th gen iTouch, 3G iPhone, and Motorola Droid Was this review helpful? Yes No Pro.Fit miniGRIP Written By NoLight, Texas on Monday, June 13, 2011 Crutchfield Customer Review (What's this?) Easy to use. Holds my ipods, Iphone, and the Blackberry that work makes me carry.. Was this review helpful? Yes No Pro.Fit miniGRIP Written By jch, Trumansburg, NY on Saturday, March 19, 2011 Crutchfield Customer Review (What's this?) Works pretty well with iPod touch in a variety of cases. The lower supports seem to fall off a bit too easily when spread for an iPod connector. Was this review helpful? Yes No Pro.Fit miniGRIP Written By Ronnie, Fort Worth, Tx on Friday, February 04, 2011 Crutchfield Customer Review (What's this?) Holder holds phone very well. Adjustable arms excellent feature for different phones 1 out of 1 people found this helpful Was this review helpful? Yes No Hands-on research What's in the box? | In-depth notes What's in the box? Pro.Fit miniGrip Holder T-AMPS adapter plate 4 Machine screws 4 Hex nuts Surface preparation cleaningkit Alcohol pre pad Product Research Features Overview: The Pro.Fit miniGRIP Universal Holder is designed to fit any devices 1-3/4" to 3-1/4" wide, and up to 4" tall. The feet on the bottom are adjustable to allow room for a plug. Its great for small flip phones or gadgets like Blackberrys, Droids or iPhones. Note: Requires compatible Pro.Fit vehicle mount. Holder Compatibility: The Pro.Fit Bravo miniGRIP Universal Holder is designed to work with any of the Pro.Fit vehicle mounts. Dimensions: Universal Holder: 2.625" - 4.0625" (w) x 3.5" (h) x 1.8125" (d) Adapter Plate: 1.6875" (w) x 2.25" (h) x 0.3125" (d) Our Product Research Team At Crutchfield, you'll get detailed, accurate information that's hard to find elsewhere. That's because we have our own in-house Product Research team. They verify what's in the box, check the owner's manual, and record dimensions, features and specs. We stay on top of new products and technologies to help people make informed choices. Sorry, the Pro.Fit miniGRIP is no longer available. Looking for a similar item? Shop all Device Holders Or, you can still... Write a review Search the website Go


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Guest DJ: Rosanne Cash
Listen to Rosanne Cash's Guest DJ'd station on iHeartRadio
Singer/songwriter Rosanne Cash (and daughter of icon Johnny Cash) has a brand new album, The River And The Thread.
"It's both real river, The Mississippi, and real thread," Rosanne Cash tells iHeartRadio. "My friend Natalie Shannon in Alabama taught me how to sew, and when she was teaching me, she threaded my needle and she said, 'You have to love the thread,' and it just sent a chill through me. She wasn't speaking in metaphors at all... but I thought yeah, the thread of your own past, the thread of your musical history, the thread that goes backwards and forwards, your parents and your children and your grandparents and your great grandchildren. The river is the same thing."
[Buy The River & The Thread on iTunes]
Rosanne Cash teamed up with iHeartRadio to Guest DJ a radio station that represents her southern sensibiblity and passion for music. Her station features an interesting mix of rock, country, standards and more. Check out the Rosanne's top ten tracks below.
1. Howlin' Wolf, "Smokestack Lightning"
"'Smokestack Lightning' by Howlin' Wolf is kind of the quintessential Delta [blues] artist and the quintessential Delta song to me," Rosanne tells iHeartRadio. "It's just so sexy and rhythmic and tough and sweet at the same time... During one of my trips to the Delta when I was writing the new record, I went to Dockery Farms where Howlin' Wolf used to work on the cotton plantation and then sit on the porch of the juke joint at night and play his songs. That was really quite powerful, to go to that area to see where he was. This is one of my favorite songs from The Delta Blues."
2. Sister Rosetta Tharpe, "Strange Things Happening Every Day"
"She's such a badass," Rosanne says. "She's a great guitar player, great singer and she's got this kind of rock star attitude even though she's this nice southern woman who sings a lot of gospel music. My dad always said she was his favorite singer. This is a really inspiring woman and a really inspiring track... Patty Griffin sings this song called 'Sister Rosetta Comes Before Us'. She was like the original badass (laughs)."
3. Bobbie Gentry, "Ode To Billie Joe"
"[This song] has this incredible blend of being a very raw, narrative story all set around the dinner table. It could be a photograph, a black and white photograph from the 1950's from the south -- it's so crystal clear -- the cinematic qualities delivered in a really beautiful, present voice. There is no voice like Bobbie Gentry's, and her acoustic guitar with the country pop background of the cascading strings... there's no other record like it, there's no other story like it." Rosanne adds, "Forty years after this song was a hit, people are still saying, 'I wonder what they threw off the bridge,' and Bobby Gentry is such an enigmatic personality. She virtually disappeared from the music business; you can't find her. In fact, I narrated a documentary for the BBC called Searching For Bobby Gentry – nobody knows where she is. She does not want to be found, so at some point early in her career she just dropped out. She had a lot of music left in her, but she didn't want to deal with the business anymore is what everybody thinks, and who can blame her?
"She was a great great artist, and I've been singing this song live in concert for several years now.
"The coolest thing happened: I sang it live at The Rainforest Foundation Benefit at Carnegie Hall a couple years ago, and President Clinton was in the audience. There was an intermission, and he kind of summoned me at the intermission to talk at length about 'Ode To Billie Joe.' He had these very well developed opinions about the song and how it represented the shame of the South; it was fascinating what he said about it. People still talk about this song 40 years after it was a hit; it's a really amazing story."
4. Johnny Cash, "Big River"
"I think 'Big River' is a perfect song; it works on so many levels," Rosanne says of her father's song. "It's a geographical trip in that it starts in Minneapolis or St. Paul, Minnesota and it ends up in New Orleans, so it takes this trip down the Mississippi River and it mentions cities along the way. On another level, it's fueled by this urgency and testosterone. He's looking for this woman, and he stops at every town along the way to look for this woman, and he doesn't find her.
"On another level I think it's a perfect piece of southern poetry. My dad's phrases and his alliteration and his onomatopoeia... it's perfect, it's almost Shakespearean. and it's one of my favorite songs of his. I chose it because it's quintessentially southern. Also I think he was looking for my mother when he wrote that song, so that makes it even more special."
5. Randy Newman, "Louisiana 1927"
"I just don't know if there is a more poetic, sadder, elegiac song about a southern state. I think Randy Newman is one of the greatest living American songwriters, and this song, this quintessential Randy Newman, it's perfect. And the way he offered the song up after Katrina was so heartbreaking and so beautiful and so perfect... he's a hero in my eyes just for that, but for the catalog of his work and this song at the centerpiece of it, you have to give it up to the guy, he's just one of the greatest."
6. Muddy Waters, "I Love the Life I Live, I Live the Life I Love"
"I love this song, not only but Muddy but by Mose Allison, so I had to choose it 'cause there's also something counterintuitive about it, just as word play it feels good to say, it feels good to sing. But it's also counter to a lot of Blues songs because the life was so hard and there was so much longing and suffering, and this one is a departure from all of that. I love it, I live it and sung by Muddy... I mean there's not much more to love about that."
7. Bob Dylan, "Highway 61 Revisited"
"Couldn't leave Dylan out of the list even though he's not southern. He wrote some great songs about the south, none greater than 'Highway 61 Revisited.' 'God said to Abraham kill me a son, Abraham said where you want this killing done, our on highway 61' -- and I took that trip down Highway 61, I guess every musician who cares about this music eventually takes the trip down Highway 61.
"In the same way the Dylan wrote 'Highway 61 Revisited' because of what had happened there and what was happening to music. We all go there because of the music, Dylan just happens to love it as much as we do and wrote the song. We started in Memphis, we drove to Oxford, Mississippi and saw where Faulkner lived and then all the way down Highway 61, ended up in New Orleans and it was a perfect trip of music and inspiration... nobody does it like Dylan. The urgency, the pictures painted, the word play, the unexpected pairings of God, Abraham and the Delta... And he's funny and he's Bob Dylan so what more could you want!?"
8. Paul Simon, "Graceland"
"He's not a southerner of course, but it's about a journey down the Mississippi river. He describes the Mississippi river -- I think the best description ever -- he calls it our national guitar, 'shining like a national guitar.' I was standing on the roof of a hotel in Memphis a couple years ago looking over the Mississippi at dusk, and this gleam came across the Mississippi and it just burst into my head, Paul Simon's line 'it's shining like a national guitar' – that was it. I get it.
"He goes to Graceland to Elvis' house, and he's taken a child on this journey with him, and you can see it, you can see this road trip and you can see him ending up there. And then Graceland of course becomes the biggest metaphor. The land of Grace and going with this child, the child of his first marriage. The details are so perfect and so deep; I never get tired of hearing that song."
9. Jesse Winchester, "Biloxi"
"It's such a beautiful song, and it has a couple of elements like 'Graceland' in that it's full of this poignancy and longing, and yet it has such a powerful sense of place. You see the sunset on the water, and you see the little boy on the sand digging the hole -- and we are walking naked. In the water there's this abandon and beauty about the song. I have never been to Biloxi, so it has this added element of mystery. If I go there will I see Jesse Winchester's Biloxi."
10. Etta James, "At Last"
"There's no voice like Etta James, and 'At Last' is the quintessential Etta James. Talk about badass! She was a badass. I was just watching her in that documentary about Muscle Shoals not long ago, and she was just this little, intense, big-voiced black woman with blonde hair and she'd just take no prisoners. You did not wanna meet her in a back alley, no! And also you don't want to go toe to toe with her in a singing contest either, it's Etta, it's Etta James... she's the bomb."
11. Rosanne Cash, "A Feather's Not A Bird"
"I'll close out this set with one of my own songs, 'A Feather's Not A Bird,' because it's the opening track on my record The River And The Thread," Rosanne tells iHeartRadio." It lays out the landscape of the south and it lays out these journeys I took through the south that inspired all these songs. It starts in Florence, Alabama and it goes to Memphis and Arkansas and Nashville -- all these places are name checked -- but there's also a sense of urgency about it too, because it's also a road trip, but it's a road trip to the past and to yourself, the sense of home that you carry in yourself. The line that I'm very happy I came up with is, 'There's never any highway when you're looking for the past.' So in the same way that some of these other songs are geographical journeys and metaphorical journeys, 'A Feather's Not A Bird' is that."
Listen to Rosanne Cash's Guest DJ'd station on iHeartRadio
Photos by Katherine Tyler for iHeartRadio


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- Home »
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- Webb Welcomes Dr. Roger I. Basu
Webb Welcomes Dr. Roger I. Basu
Webb is pleased to announce Roger I. Basu as our newest professor. Dr. Basu is a structural engineer with over thirty years of experience. His early experience was in the structural design and analysis of offshore structures, bridges and buildings. For the last twenty years his focus has been exclusively on ship and offshore structures. His experience in more specialist areas includes fatigue, fracture and vibration analysis, and risk and reliability methods.
Prior to joining the American Bureau of Shipping (ABS) in 1997 he was employed for 10 years at a naval architectural firm in Ottawa, Canada where he worked on a variety of structural design tasks on naval and other ships and led the company's noise, vibration, shock and blast group. Roger participated in a number of Ship Structure Committee projects including one as principal investigator and another as Chairman of the Project Technical Committee. At ABS he was formerly Manager of the Advanced Analysis Department and is currently Director of Research & Product Development where he is responsible for applied research in support of the development of tools and technologies for the assessment of ship and offshore structures. Roger is active in various international organizations including as Chairman of the Standing Committee of PRADS 2007 and as a member of the International Advisory Committee of OMAE.
Roger has published or presented about 40 technical papers. He holds a Ph.D. in structural engineering from the University of Western Ontario, London, Canada.


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What are they and what are they used for? And how are they different from regular SLR or DLSR cameras?
Take the 2-minute tour ×
Photography Stack Exchange is a question and answer site for professional, enthusiast and amateur photographers. It's 100% free, no registration required.
"Format" refers to the size of the recording medium in a camera. I say recording medium because the term originated in the film era and has continued to the digital age.
There are no hard limits but medium format is typically anything larger than 35mm film up to 6cmx7cm film. Large format is typically everything from 4"x5" up.
In addition to the size of the film or sensor there are a number of features typical of medium and large format cameras:
Medium format
Large format


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Defensive Tackle: (DE denotes the player could also draw interest as a 5-technique with teams that employ an odd front, or already play the DE position in an odd front in college)
Tier 1 (Top 25-50 Grade)
Star Lotulelei / Utah
Sylvester Williams / North Carolina
Joe Vellano / Maryland
Kawann Short / Purdue
Margus Hunt / SMU (DE)
Tier 2 (Top 75-125 Grade)
Brandon Williams / Missouri Southern
John Jenkins / Georgia
Jake McDonough / Iowa St. (DE)
Jesse Williams / Alabama
Jordan Hill / Penn St.
Kapron Lewis-Moore / Notre Dame (DE)
A.J. Francis / Maryland (DE)
Chris Jones / Bowling Green
Tier 3 (Top 150-200 Grade)
Damion Square / Alabama (DE)
Izaan Cross / Georgia Tech (DE)
Abry Jones / Georgia (DE)
Scott Vallone / Rutgers
Baker Steinkuhler / Nebraska (DE)
Quinton Dial / Alabama (DE)
Larry Black / Indiana
Cory Grissom / South Florida
Tier 4 (Top 225-250 Grade)
Jamarkus McFarland / Oklahoma
Anthony Rashad-White / Michigan St.
Josh Mauro / Stanford (DE)
Everette Dawkins / Florida St.
Josh Boyd / Mississippi St.
Joe Vellano also plays DE in an odd front for Maryland, but it won't be his best position in the NFL. He's a better fit for a pure 3-technique, as he doesn't have the ideal length that you're looking for in a 5-tech.
Jake McDonough is the one of the most underrated defensive players in the country at nose tackle for Iowa St. All he does is soak up double-teams at the point of attack and stand his ground. However, I think his build at 6'5", 280 pounds is ideal for the 5-technique if he tests well enough athletically. He's already adept at 2-gapping.
Purdue will often use Kawann Short lined up at DE although he doesn't have the same impact there. He's better disrupting the B-gap attacking the outside shoulder of the guard as a traditional 3-technique.


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Standard or low camber provides the stability at higher speeds many shreds can't live without. The amount of snap and pop you get from a cambered board is unrivalled by any other camber designs. If you like to haul ass and go big, camber is irreplaceable.
Pantera SC
Standard Camber
Response Rating
About the
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Well-balanced layers of carbon fiber establish a new level in performance. More snap and liveliness provide a smooth, powerful and effortless ride.


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The Beat the Blues Sweepstakes is no longer open. The winner has been notified by e-mail. Thanks to everyone who entered.
Sierra Club Beat the Blues - Get Outdoors! Sweepstakes Official Rules
1. How to enter: No purchase necessary. A purchase will not increase your chances of winning. The Sierra Club Beat the Blues - Get Outdoors! Sweepstakes ("Sweepstakes") begins at 12:00 a.m. Pacific standard time (PST) on December 19, 2006, and ends at midnight PST on February 28, 2007 ("entry period"). To enter, go to www.sierraclub.org/getoutdoors. Follow the directions to complete the entry form and click Submit. Entrants must complete all data requested on the form. Entrants will receive Sierra Club's biweekly email newsletter, the Sierra Club Insider, and will be informed of Sierra Club issues and special offers.
If you do not wish to receive the Sierra Club's biweekly email newsletter and to be informed of Sierra Club issues and special offers via email or to enter online, you may also enter the Sweepstakes by printing your name, address, city, state, zip code, telephone number, e-mail address (optional), the words " Sierra Club Beat the Blues - Get Outdoors! Sweepstakes" on a 3-by-5 inch card and mailing it to: Sierra Club Beat the Blues - Get Outdoors! Sweepstakes, 85 Second St., 2nd Floor, San Francisco, CA 94105-3459. The Sierra Club must receive all entries by February 28, 2007. Limit one entry per person. All entries become the property of the Sierra Club and will not be acknowledged or returned. Illegible, photocopied, incomplete, or other mechanically reproduced entries are void.
The Sierra Club assumes no responsibility for lost, late, misdirected, stolen, illegible, mutilated, altered, damaged, incomplete, or postage-due entries or for any computer, online, telephone, cable, network, electronic, or Internet hardware or software malfunctions, failures, connections, availability, traffic congestion, or garbled or jumbled transmissions or service provider, Web site, or other accessibility or availability issues, unauthorized human intervention, or any other error, omission, or technical malfunction that may occur. Entrants shall be the authorized account holder of the e-mail address submitted at the time of entry. "Authorized account holder" is defined as the natural person who is assigned to an e-mail address by an Internet access provider, online service provider, or other organization (e.g., business, educational institution, etc.) that is responsible for assigning e-mail addresses for the domain name associated with the submitted e-mail address.
2. Eligibility: The Sweepstakes is only open to legal residents of the United States (excluding Puerto Rico, Tennessee, and Rhode Island) who are 18 years of age or older on the date the Sweepstakes begins. Employees of the Sierra Club and its subsidiaries, affiliates, prize suppliers, and advertising and promotional agencies, their immediate families (spouses, parents, children, and siblings and their spouses), and individuals living in the same household as such employees are ineligible. The Sweepstakes is governed by the laws of the United States and is subject to all applicable federal, state, and local laws and regulations. Void in Puerto Rico, Tennessee, Rhode Island, and wherever prohibited by law with no exceptions.
3. Judging: The winner will be selected by a random drawing around March 30, 2007, from all eligible entries received. The prize drawing will be conducted at the Sierra Club's office at 85 Second St., San Francisco, CA 94105-3459. By participating, entrants agree to be bound by the Official Rules and the decisions of the judges, which shall be final and binding in all respects. The odds of winning depend on the total number of eligible entries received. Limit one prize per person, family, or household from any Sierra Club-sponsored contest or Sweepstakes. The winner will be notified via e-mail, U.S. mail, and/or by overnight courier.
4. Prize: Prize and approximate retail value (ARV): One prize winner will receive his/her choice of one of any of Sierra Club's trips under $1,500 (one thousand five hundred dollars) OR a $1,500 (one thousand five hundred dollar) gift certificate toward any more expensive trip offered by Sierra Club Outings. The prize's total ARV is $1,500.00. See list of trips.
Prize cannot be exchanged for cash and cannot be used in conjunction with any other promotion. The Sierra Club reserves the right to substitute a prize of equal or greater value in the event any offered prize is unavailable. No substitution or transfer of prize permitted except as provided for at the sole discretion of the Sierra Club.
The prize winner must complete all forms required by the Sierra Club to participate on trips offered by Sierra Club Outings (e.g., Medical Form, Participant Approval Form, and Acknowledgement of Outing Member Responsibility, Express Assumption of Risk, and Release of Liability Form) or the prize will be forfeited. Sierra Club Outings leaders review these forms to make sure that each trip applicant has the appropriate equipment, experience, and physical conditioning to participate in the outing. The leader will contact the prize winner if he/she is not approved for the trip selected. In this case, the prize winner may select another, more suitable trip, or the prize is forfeited.
5. General conditions: All federal, state, and local taxes, fees, and surcharges on prize packages are the sole responsibility of the prizewinner. The prizewinner will be required to execute and return, as directed, an Affidavit of Eligibility/Release of Liability/Prize Acceptance Form within ten (10) days following notification that the winner has won the prize. Return of a prize notification as undeliverable, failure to sign and return an Affidavit of Eligibility/Release of Liability/Prize Acceptance Form, or any other failure to comply with any official rules will result in disqualification and the selection of an alternate winner. Each winner grants the Sierra Club the right to use and publish his or her legal name and state of residence online and in print, or any other media, in connection with the Sweepstakes. Acceptance of a prize constitutes permission for the Sierra Club and its affiliates and their advertising and promotional agencies to use the prizewinner's names and likenesses for editorial, advertising, and promotional purposes without payment of additional compensation unless prohibited by law. By entering, participants release and hold harmless the Sierra Club and its respective parents, subsidiaries, affiliates, directors, officers, employees, attorneys, agents, and representatives from any and all liability for any injuries, loss, claim, action, demand, or damage of any kind arising from or in connection with the Sweepstakes, any prize won, any misuse or malfunction of any prize awarded, participation in any Sweepstakes-related activity, or participation in the Sweepstakes.
As a condition of participating in the Sweepstakes, the participant agrees that any and all disputes that cannot be resolved between the parties, and causes of action arising out of or connected with the Sweepstakes, shall be resolved individually, without resort to any form of class action, exclusively, before a court of competent jurisdiction located in San Francisco, CA, which court shall apply the laws of the state of the California without regard for rules of conflicts of law. In any such dispute, the participant shall, under no circumstances, be entitled to claim punitive, incidental, or consequential damages or any other damages, including attorneys' fees, other than the participant's actual out-of-pocket expenses (if any) associated with participating in the Sweepstakes, and the participant hereby waives all rights to have damages multiplied or increased. Caution: Any attempt by a contestant or any other individual to deliberately undermine the legitimate operation of the Sweepstakes is a violation of criminal and civil laws, and should such an attempt be made, the Sierra Club reserves the right to seek damages from any such contestant to the fullest extent permitted by law.
6. Limitations of liability: The Sierra Club is not responsible for any incorrect or inaccurate information caused by any technical or human error that may occur in the processing of submissions in the Sweepstakes, including but not limited to any misprints or typographical errors or computer failure. The Sierra Club assumes no responsibility for any error, omission, deletion, defect, theft, destruction, or unauthorized access to, or alteration of, entries. If, for any reason, the Sweepstakes is not capable of completion as planned--including by reasons of tampering, unauthorized intervention, fraud, technical failures or any other causes beyond the control of the Sierra Club that corrupt or affect the administration, security, fairness, integrity, or proper conduct of the Sweepstakes--the Sierra Club reserves the right at its sole discretion to cancel, terminate, modify, or suspend the Sweepstakes.
7. Names of the winner: For the winner's name, send a self-addressed, stamped envelope after March 31, 2007, to: Sierra Club Beat the Blues - Get Outdoors! Sweepstakes, 85 Second St., 2nd Floor, San Francisco, CA 94105-3459.