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Interpretive Handbook
87938 :
IgA Subclasses, Serum
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
IgA, the predominant immunoglobulin secreted at mucosal surfaces, consists of 2 subclasses, IgA1 and IgA2. IgA1 is the major (approximately 80%) subclass in serum. IgA2 is the major subclass in secretions such as milk. Although IgA deficiency is a common defect (1 in 700), it is usually asymptomatic. IgA deficiency with or without IgG subclass deficiency, however, can lead to recurrent pulmonary and gastrointestinal infections. Some infections (eg, recurrent sinopulmonary infections with Haemophilus influenzae) may be related to a deficiency of IgA2 in the presence of normal total IgA concentrations.
Paradoxically, bacterial infections may also cause IgA deficiency. For example, IgA1 (but not IgA2) can be cleaved and inactivated by certain bacteria, thus depleting the majority of the IgA. In the presence of a concurrent IgA2 deficiency, infection by these organisms results in an apparent IgA deficiency.
IgA deficiency is 1 cause of anaphylactic transfusion reactions. In these situations, IgA-deficient patients produce anti-IgA antibodies that react with IgA present in the transfusion product. While transfusion reactions typically occur in patients who have no detectable levels of IgA, they can occur in patients with measurable IgA. In these situations, the complete deficiency of 1 of the IgA subclasses may be the cause of the transfusion reactions.
Useful For Suggests clinical disorders or settings where the test may be helpful
Investigation of immune deficiency due to IgA2 deficiency
Evaluating patients with anaphylactic transfusion reactions
Interpretation Provides information to assist in interpretation of the test results
Low concentrations of IgA2 with normal IgA1 levels suggest an IgA2 deficiency.
Elevated concentrations of IgA2 with normal or low amounts of IgA1 suggest a clonal plasma cell proliferative disorder secreting a monoclonal IgA2.
Increased total IgA levels also may be seen in benign disorders (eg, infection, inflammation, allergy), hyper IgD syndrome with periodic fever and monoclonal gammopathies (eg, myeloma, monoclonal gammopathies of undetermined significance [MGUS]).
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
0-<5 months: 7-37 mg/dL
5-<9 months: 16-50 mg/dL
9-<15 months: 27-66 mg/dL
15-<24 months: 36-79 mg/dL
2-<4 years: 27-246 mg/dL
4-<7 years: 29-256 mg/dL
7-<10 years: 34-274 mg/dL
10-<13 years: 42-295 mg/dL
13-<16 years: 52-319 mg/dL
16-<18 years: 60-337 mg/dL
> or =18 years: 61-356 mg/dL
0-<5 months: 10-34 mg/dL
5-<9 months: 14-41 mg/dL
9-<15 months: 20-50 mg/dL
15-<24 months: 24-58 mg/dL
2-<4 years: 16-162 mg/dL
4-<7 years: 17-187 mg/dL
7-<10 years: 21-221 mg/dL
10-<13 years: 27-250 mg/dL
13-<16 years: 36-275 mg/dL
16-<18 years: 44-289 mg/dL
> or =18 years: 50-314 mg/dL
0-<5 months: 0.4-5.5 mg/dL
5-<9 months: 1.5-6.2 mg/dL
9-<15 months: 2.8-7.0 mg/dL
15-<24 months: 3.9-7.7 mg/dL
2-<4 years: 1.3-31.1 mg/dL
4-<7 years: 1.1-39.1 mg/dL
7-<10 years: 1.4-48.0 mg/dL
10-<13 years: 2.6-53.4 mg/dL
13-<16 years: 4.7-55.1 mg/dL
16-<18 years: 6.6-54.3 mg/dL
> or =18 years: 9.7-156.0 mg/dL
Clinical References Provides recommendations for further in-depth reading of a clinical nature
1. Schauer U, Stemberg F, Rieger CHL, et al: Establishment of age-dependent reference values for IgA subclasses. Clin Chim Acta 2003;328:129-133
2. Saulsbury FT: Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) in a child with normal serum IgD, but increased serum IgA concentration. J Pediatrics 2003:127-129
3. Popovsky MA: Transfusion Reactions. American Association of Blood Banks, Third edition, 2007


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Health Hazards Connected To Electronic Cigarettes
There is a rising popularity for the e cigarettes or electronic nicotine delivery systems today even if little details are known pertaining to them. In The USA, these e-cigarettes are easily available in almost all shopping centers in many states. But in fact, how risk-free could they truly be?
There was initially five electronic cigarette brands which were examined by researchers in order to answer this inquiry today. They were capable to realize that several design flaws and health issue concerns were discovered with these new items. They then had figured that the electronic cigarettes were potentially harmful to people and has then prompted to have them removed in the market. (read a green smoke review here or v2 cigs review here to learn more about these brands)
As opposed to the normal cigarettes that consume tobacco when smoked, these items will be vaporizing nicotine with other compounds along with it too. This is going to come out by means of aerosol that is attained by heating and does not produce toxic chemicals caused by tobacco. There isn't any information nevertheless concerning the chemicals located in the aerosolized vapors.
Because of this, there are numerous individuals who have viewed the electronic cigarettes as a safer alternative to conventional cigarettes. Yet there aren't any virtual scientific studies regarding their safety. One of the studies has nevertheless shown that it had many flaws which may be the explanation of serious health conditions.
Even though there are issues about the health problems as of the moment, these items have not been banned. They are simply however prohibited in Australia, Canada, Brazil and New Zealand nowadays. The individual electronic cigarettes are known to contain a wider variety of nicotine levels even though they have been labeled as a light dosage. There has also been little quality control used with regards to the additives employed in flavoring.
In a number of countries, the government regulatory boards are actually deciding on the way they should classify the electric cigarettes and ensure its high quality. An extremely volatile battle happens to be growing between the conventional cigarette brands and also the electronic cigarette industry today. This struggle is not about consumer loyalty by itself. The electronic brands are competing to their very own goods labeled as a tobacco product by way of court battles as well.
The nicotine created in tobacco is known to be benign when compared to smoke. This habit forming component is exactly what has kept many men and women from returning to this. The injury in smoking nonetheless comes mainly from inhaling the tobacco smoke. Nicotine is comparatively harmless to individuals once it's been removed from tobacco in their purest state. By sucking in the e-cigarette vapor, aerosol is introduced that contains nicotine and goes into the lungs even though the residue is expelled.
The liquid nicotine is heated through small batteries in the e cigarettes which turns it into watery vapor. The steam will consist of water flavoring and propylene glycol which is actually a solution. It might be too early yet to be aware what the certain electronic cigarette side effects are for e-cigarettes since the products are very new. Extensive medical testing ought to be done first of all which leaves those with many questions un-answered.

subset: commoncrawl


text: With Bay Photo's Canvas Prints, you can display your photos like a fine art canvas. Canvas Prints can be made from prints on Professional Photo Papers bonded onto museum quality canvas, or Giclée Fine Art Prints printed directly onto the canvas material. The resulting prints can then be stretched and stapled onto a wood artists stretcher bar frame, mounted on gator board, or delivered loose (unmounted).


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FALLS CHURCH, Va. — The U.S. Food and Drug Administration is advising consumers to stop using OxyElite Pro, a dietary supplement, because of suspected links to acute hepatitis.
The FDA, along with the Centers for Disease Control and Prevention and the Hawaii Department of Health are investigating reports of acute non-viral hepatitis in Hawaii where 29 cases are linked to a dietary supplement. The FDA urges consumers to stop using the product while the investigation continues. Distributed by USPlabs LLC in Dallas, Texas, the product is sold nationwide in retail stores and on the internet.
"We are urging Airmen to stop using the product until the investigation concludes and results are confirmed," said Col. John Oh, chief of Health Promotion, Air Force Medical Support Agency, Air Force Surgeon General.
There have been a total of 29 cases of acute non-viral hepatitis with an unknown cause reported in Hawaii. Eleven of the 29 patients have been hospitalized with acute hepatitis, two have received liver transplants and one person has died. The CDC is also investigating other cases of liver injury nation-wide that could be related.
Symptoms of hepatitis include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, clay or gray-colored bowel movements, joint pain, yellow eyes and jaundice.
"Airmen who are experiencing these symptoms should contact their health care provider immediately," said Colonel Oh. Many Airmen reportedly use dietary supplements for weight loss or muscle building. In 2011, one-third of Airmen reported using legal bodybuilding supplements in the past year, including 15 percent in the last month, according to Oh.
"We encourage Airmen to get educated on dietary supplement safety through Operation Supplement Safety, the Department of Defense dietary supplement education and safety campaign," said Oh. Information about the campaign is found at: www.hprc-online.org/opss.
Visit www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm370857.htm for more information about the FDA. If you believe you have been harmed by this or other dietary supplements and over-the-counter products, report incidents to the FDA, using the form at www.fda.gov/MedWatch/report.htm.


text: Hey, if we don't get this wiin we are 1-4 and basically out of it. With this hard fought win we have hope, we're a game out of first place in our division and we have 5 winnable games coming up on the schedule. Not to mention we have our franchise quarterback in Ryan Tannehill and we have a very competent Head Coach in Joe Philbin. Go Fins!


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Top Definition
When a man and woman cuddle whilst his penis is inside her vagina. They aint fucking, they aint cuddling. They are fuddling
Tom had his penis inside Jennifer whilst they spooned. As there wasnt any movement they werent fucking, but it wasnt a cuddle either. They were fuddling.
di Graham Pike 18 dicembre 2013


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I needed a welding cart for my 211 and wanted a place to store all my welding paraphernalia. I had seen a cart made from a file cabinet on this site some time ago and decided that it was the way to go.
Welding helmets, gloves and bottle wrenches go in the top drawer and the spool welder and extra wire goes into the bottom.
The big wheels came off an obsolete lawn mower and make for really smooth pulling around the shop and driveway.
The whole thing is high enough that I do not have to bend down to change wire and speed settings.
The whole thing only took about an hour to build.
Cart Front.jpg
Cart Side.jpg
Results 1 to 4 of 4
Thread: File Cabinet Welding Cart
Hybrid View
03-18-2014, 11:50 PM #1Junior Member
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- Jun 2013
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File Cabinet Welding Cart
03-19-2014, 12:46 PM #2Senior Member
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- Dec 2010
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- Andover, Ohio
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Welcome to the forum Denny98501.
Also nice job on your cart.
03-19-2014, 01:22 PM #3Member
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- May 2013
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- Cantonment, FL
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That is pretty slick!!
03-21-2014, 04:04 AM #4Junior Member
Originally Posted by mbramble:318873
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- Feb 2013
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Adding that to the "stolen ideas" file.


text:
I think one of the biggest oversights in the development of the Multimatic 200 is the lack of MVP plug options for 230VAC.
Oddly, Miller chose to produce two MVP plugs for 115VAC (#219-259 & #219-261), even though there is virtually no advantage to having the NEMA 5-20P option, as the NEMA 5-15P plug will plug into a typical NEMA 5-20R receptacle.
So why only one plug for 230V (#219-258)? Furthermore, the NEMA 6-50R receptacle is not typically found outside of welding shops, or specific farm & industrial locations. It does make sense to provide a NEMA 6-50P MVP plug for larger welders that are going to spend most of their time in a dedicated welding shop location. But the primary advantage of the Multimatic 200 -- in fact, I would say its main selling point -- is that it is designed as a portable lightweight unit designed to go "to the job." But how many construction or maintenance job sites are going to have a NEMA 6-50R receptacle available? I've never encountered one. Even the typical construction site generator doesn't have a NEMA 6-50R receptacle. What are commonly available are NEMA 6-20R (straight) or NEMA L14-30R (locking).
This means we must make our own adapter cord, or we must limit the Multimatic 200 to 115VAC use. This defeats the entire purpose of the MVP plug and diminishes the portability, compactness, and versatility of the Multimatic 200. And let's be clear: making your own adapter is not cheap: just the NEMA 6-50R connector alone for making your own adapter cord will run $50 to $100.
None of this makes any sense. My suspicion is that the MVP was developed for Miller's other product lines, and that it was then carried over to the Multimatic 200. Perhaps not as an afterthought, but without consideration of the Multimatic's objective as a stand-alone roving welding shop.
So is Miller going to expand the MVP plug options? I certainly hope so.
Results 1 to 10 of 11
Thread: MVP Plug on Multimatic 200
01-13-2014, 07:41 PM #1Junior Member
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MVP Plug on Multimatic 200
01-13-2014, 08:32 PM #2Senior Member
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- Northern Arizona
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I don't know where you shop but I can build a 6-50r to 14-50p or 14-30p for about $35. A 6-50r to l14-30r would run me about the same. This is all with 8/3 wiring.
I know what you are getting at but you seem to be pricing the adapter cords pretty high. I like to have adapters around because then i can plug anything into those receptacles. Within reason of course. It would be nice to have MVP plugs with more variety but I don't have anything with MVP... so I just wire my own stuff up. Good luck.MillerMatic 251
Maxstar 150 STH
Cutmaster 42
Victor Journeyman OA
A rockcrawler, er money pit, in progress...
01-14-2014, 12:34 PM #3Junior Member
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- Aug 2013
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What I was referring to are specific cord-end connectors. The lowest cost one I found was made by ArrowHart and sold by Galco:
This connector cost me $39.47 plus $13.75 shipping to California. Other suppliers and other makes were priced significantly higher, up to over $100 for this type of NEMA 6-50R connector.
I don't know how much it costs Miller to produce an MVP adapter, but it seems to me they are losing money by not offering additional adapters.
And I still can't come up with a reason for Miller offering a NEMA 5-20P MVP plug, but NOT offering any other 230V MVP plugs.
01-14-2014, 01:54 PM #4Senior Member
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- Feb 2009
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- Lodi, CA
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Very simple, Cost. Do you have any idea of the manufacturing costs involved with those MVP plugs? Versus the cost of somebody making thousands of generic extension cord plugs? Much as many refuse to admit, Miller is a publicly owned company, and does need to make PROFIT. Miller is NOT a public charity. They provide one plug for 120, one plug for 240, it is up to you to make them work. Get over it, make an adapter, and start welding.Obviously, I'm just a hack-artist, you shouldn't be listening to anything I say .....
01-14-2014, 02:05 PM #5Senior Member
Obviously, I'm just a hack-artist, you shouldn't be listening to anything I say .....
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01-14-2014, 05:34 PM #6Junior Member
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- Aug 2013
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And you're wrong about what Miller offers: they have one plug for 230V and two plugs for 120V. They include one 120V plug and one 230V plug with the Multimatic 200. But they sell the third plug (120V) as an option. Do you think they sell that at cost? I'll wager they sell all their MVP plugs for a profit.
The question is why did Miller decide to make a NEMA 5-20P as an option (which I'll wager they sell very few of, if any), when NEMA L14-30P and NEMA 6-20P options would be significantly more useful and SELLABLE as options (thus increasing profits for their shareholders).
Even if I were to make or buy a cheapo adapter as suggested by Elvis in this thread, that's still $35 for each adapter, which is $16 more than what Miller charges for their most expensive MVP plug (the 230V NEMA 6-50P). Do you think it's a wise business decision for Miller to allow other companies to take all that extra profit from Miller?
By your line of reasoning, one must wonder: why did Miller even develop their custom MVP in the first place?
01-14-2014, 07:08 PM #7Senior Member
- Join Date
- Jan 2008
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- 328
They used to have 4 plugs
If I remember correctly they did have the 30 amp dryer plug in the 2010 or 2011 catalog. Maybe it was the 14-50 plug. Hobart only includes 1 115 and 1 240 plug. The discontinued 240 volt plug was $30+ . Find the part number and try to order one. I have 2 adapters hanging on the wall...a dryer plug and 4 prong twistlock for a generator.
01-15-2014, 12:44 PM #8Junior Member
- Join Date
- Aug 2013
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- 6
Some marketing person at Miller may be thinking, we don't sell enough MVP plugs as add-on purchases to make this a worthwhile manufacturing investment. I would argue that the reason is because Miller is not offering the MVP plug options that the market is demanding. Right now, the only MVP plug being sold that is not already included with the welding machine is the NEMA 5-20P, which seems to be a solution in search of a problem.
Deafman found the need to make two 230V adapters. I have an immediate need for two 230V adapters (and may need a drier outlet adapter in the future). I bet if we polled most users with portable welders, the vast majority of them would have at least one adapter. Imagine if, for every MVP welder sold by Miller or Hobart, they also sold one, two, or more MVP plugs as add-on purchases, and that each MVP plug had a 100% profit margin (or more). Those are a lot of consumer dollars Miller could be capturing instead of those dollars going to other companies as they are now. And then the MVP plug would realize its full potential!
My recommendation is that Miller offer at least the following three additional MVP plugs: NEMA L14-30P; NEMA 6-20P; and NEMA 14-30P.
01-17-2014, 04:13 PM #9Junior Member
- Join Date
- Jan 2014
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- 2
When adapting the miller plug to a nema L14-30, is the neutral not used?
I can't find an adapter ready to buy so I need to put one together.
All suggestions appreciated.
01-17-2014, 07:48 PM #10Ed Conley
Passport Plus w/Spool Gun
Miller 125c Plasma 120v
O/A set
SO 2020 Bender
You can call me Bacchus


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Answers FAQ
Multiple Sclerosis (MS) FAQs
Reviewed by Charles P. Davis, MD, PhD
Test your Knowledge!
- What kind of disease is multiple sclerosis?
- What does the body's nervous system control?
- What is myelin?
- Which is a common symptom of MS?
- Do people die from MS?
- What is the meaning of the term "multiple sclerosis"?
- Multiple sclerosis is only seen in adults. True or False?
- The clear cause of MS remains unknown, though what may be important factors?
- Interruptions between nerve cells can cause additional MS symptoms such as?
- There are currently no treatments for MS. True or False?
- Improve your Health I.Q. on Multiple Sclerosis (MS)
- Multiple Sclerosis (MS) Related Slideshows
- Multiple Sclerosis (MS) Related Image Collections
Q:What kind of disease is multiple sclerosis?
A:An autoimmune disease. Multiple sclerosis or MS, is an autoimmune disease. A healthy, functioning immune system seeks to protect the body by attacking foreign bodies and substances; autoimmune diseases occur when the body's immune system attacks itself. With MS, the immune system attacks the body's tissues (brain and spinal cord myelin is damaged or destroyed).
Q:What does the body's nervous system control?
A:The five senses, Balance and blood pressure and Thought and reason. The nervous system is an elaborate arrangement of particular nerve cells that helps the human body interact with the outside world through senses and reasoning. The nervous system is comprised of two parts: the central nervous system (CNS), which includes the spinal cord and the brain, and the peripheral nervous system (PNS), which controls movements and functions, both voluntary and involuntary.
Q:What is myelin?
A:A fatty coating surrounding nerves and A nerve insulator. Myelin (myelin sheath) is an insulating coating surrounding the nerves that allows the passage of nerve impulses to support coordination and muscle movement. As seen with MS, defensive immune system attacks destroy this myelin coating, interrupting the way in which the nervous system communicates and behaves within the body. The process by which myelin depletes is referred to as "demyelination."
Q:Which is a common symptom of MS?
A:Imbalance. Because the movement-controlling nerves in the brain and spinal cord are under assault, people with MS may experience imbalance as a common symptom. MS patients are also likely to suffer impaired walking, standing, and coordination. MS progresses as more nerves are attacked, causing nervous system interferences that affects vision, speech, writing, and memory.
Q:Do people die from MS?
A:No. Most people who develop MS can manage the disease over time. Oftentimes, people become disabled, but life-threatening MS is rare and does not necessarily reduce a person's life span.
Q:What is the meaning of the term "multiple sclerosis"?
A:"Many locations of scar tissue". The term "multiple" refers to the multiple places in the central nervous system that are affected and to the multiple relapses and remissions characteristic of MS. The term "sclerosis" refers to localized hardening or scarring in the body. With MS, scar tissue called plaques form as myelin is destroyed.
Q:Multiple sclerosis is only seen in adults. True or False?
A:False. Most frequently, early signs and symptoms of MS are observed in young to middle adulthood. There are rare cases, though, where children develop a varied type of MS called Schilder's disease. Much like classic MS, symptoms of Schilder's disease are progressive, myelin-depleting, and debilitating. Schilder's symptoms can include: dementia, incontinence, instability, and tremors.
Q:The clear cause of MS remains unknown, though what may be important factors?
A:Environment, viruses, and genetics. Doctors, scientists, and researchers have yet to pinpoint the exact cause of multiple sclerosis. Still, recent years of dedicated research suggest that the immune system activity witnessed with multiple sclerosis may be trigged by the affected individual's environment, family history, or perhaps even a virus.
Q:Interruptions between nerve cells can cause additional MS symptoms such as?
A:Urinary incontinence, Visions problems or loss and Muscle weakness. Urinary incontinence and other bladder problems; vision problems, vision loss, eye pain, double vision, muscle spasms, and limb weakness are symptoms that are commonly seen with MS. It is important to note that the length and frequency of MS signs and symptoms may vary from patient to patient.
Q:There are currently no treatments for MS. True or False?
A:False. Thanks to strides in medical research and science, there is hope for people with MS. A number of disease-modifying drugs are now on the market to suppress or alter the body's immune system. Additional drug therapies can help reduce the frequency and severity of MS flares and slow the progression of the disease.
Source quiz on MedicineNet
Improve your Health I.Q. on Multiple Sclerosis (MS)back to top ↑
Multiple Sclerosis (MS) Related Slideshows
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Multiple Sclerosis
Get the latest treatment options.


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What people are saying about Elvis On Tour - The Legend Continues
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