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Loop Electrosurgical Excision Procedure
- Home
- Your Health
- Loop Electrosurgical Excision Procedure
Loop Electrosurgical Excision Procedure
(LEEP, LLETZ—Large Loop Excision of the Transformation Zone, LLEC—Large Loop Excision of the Cervix, Loop Cone Biopsy of the Cervix)
Reasons for Procedure
Possible Complications
- Bleeding
- Abdominal cramping
- Infection
- Future pregnancy problems (small increased risk of premature births and having a low birth weight baby)
- Narrowing of the cervix (very rare)
- Incomplete removal of the abnormal tissue
- Accidental cutting or burning of normal tissue
- Smoking
- Drinking
- Chronic disease such as diabetes or obesity
- Menstruation at the time of the procedure—It is best to have LEEP done when you do not have your period.
- History of pelvic inflammatory disease
- Inflammation of the cervix
- Pregnancy or possible pregnancy
What to Expect
Prior to Procedure
- If your doctor will be giving you a sedative, arrange for someone to drive you home from the clinic.
- If directed by your doctor, take a pain reliever right before the LEEP.
- Bring sanitary napkins to use after the procedure.
Description of the Procedure
How Long Will It Take?
How Much Will It Hurt?
Post-procedure Care
- Washing their hands
- Wearing gloves or masks
- Keeping your incisions covered
- Washing your hands often and reminding visitors and healthcare providers to do the same
- Reminding your healthcare providers to wear gloves or masks
- Not allowing others to touch your incisions
- Dark brown-black vaginal discharge for several days
- Mild cramping
- Watery pink discharge
- Rest when you get home.
- Frequently change the sanitary pad.
- Take pain medicine as directed.
It will take a few weeks for your cervix to heal. For four weeks:
- Do not use tampons or douches.
- Refrain from sexual intercourse.
- Do not do any heavy lifting.
- It is okay for you take baths and showers.
- If advised by your doctor, have a Pap test and pelvic exam every six months.
Call Your Doctor
- Heavy bleeding (more than your normal period)
- Bleeding with clots
- Severe abdominal pain
- Fever or chills
- Unusual odor or discharge
American Congress of Obstetricians and Gynecologists http://www.acog.org
Family Doctor—American Academy of Family Physicians http://familydoctor.org
Canadian Women's Health Network http://www.cwhn.ca
Society of Obstetricians and Gynaecologists of Canada http://www.sogc.org
American Congress of Obstetricians and Gynecologists. Management of abnormal cervical cytology and histology. Practice Bulletin. 2010; 99.
Emam M, Elnasar A, Shalen H, Barakat R. Evaluation of a sinfle-step diagnosis and treatment of premalignant cervical lesions by LEEP. Int J Gynaecol Obstet. 2009;107(3):224-7.
Loop electrosurgical excision procedure (LEEP). American Congress of Obstetricians and Gynecologists website. Available at: http://www.acog.org/Patients/FAQs/Loop-Electrosurgical-Excision-Procedure-LEEP. Updated July 2014. Accessed August 15, 2014.
Loop electrosurgical excision procedure (LEEP). American Society for Colposcopy and Cervical Pathology website. Available at: http://www.asccp.org/Education/COURSES-Comprehensive-Colposcopy-HRA-Advanced-and-more/Loop-Electrosurgical-Excision-Procedure-LEEP. Accessed August 15, 2014.
Neff D. Endometrial ablation. EBSCO Health Library website. Available at: http://www.ebscohost.com/healthLibrary. Updated January 28, 2014. Accessed August 15, 2014.
Noehr B, Jensen A, Kjaer SK. Depth of cervical cone removal by loop electrosurgical excision procedure and subsequent risk of preterm delivery. Obstet Gynecol. 2009;114(6):1232-8.
Revision Information
- Reviewer: Andrea Chisholm, MD
- Review Date: 08/2014 -
- Update Date: 01/28/2014 -


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NELLIS AIR FORCE BASE, Nev. — Starting in basic military training, through technical school, to their first duty station and beyond, Airmen are advised to stay in control of their finances.
According to Air Force Instruction 36-2906, Personal Financial Responsibility, military members, "will pay their just financial obligations in a proper and timely manner."
Becoming financially irresponsible comes with consequences, especially in the military.
Master Sgt. Cristy Anderson, 53rd Test and Evaluation Group first sergeant, says leadership does not want to get their Airmen in trouble. Instead, they encourage them to contact their leadership before there is a financial problem so administrative punishment doesn't become a factor.
"We can't make someone do an allotment, we can't make you pay your bill, [or] order you to do that. But if you're not going to do it, there will be a consequence," she said.
"We want to help you; we want to get you on the right road to success. If we continue to have a problem, then some people may document a verbal [counseling], and if that still doesn't fix it, you are looking at a [letter of counseling], [letter of reprimand], or all the way up to an Article 15.
"Discipline is progressive, you may find yourself discharged and out the gate" Anderson said.
Letting your finances get out of hand and falling into trouble can not only affect your military career, but it can affect your life outside of uniform as well.
"[Financial trouble] can harm your credit score, and these days your credit score means a lot," said Quan Franklin, airman and family readiness center community readiness specialist. "A poor credit score can affect security clearances, loans, rent applications and more."
If you find yourself in financial trouble, there are programs and strategies in place to get you back on track.
"Once you set a goal and determine that this is what you want to do, what you need to do to get to where you want to be, then it is possible," Franklin said. "It first starts with the individual."
"A lot of times a lot of problems can be solved by starting a budget" she added. If you need help preparing a budget, the AFRC can assist you.
Preventing financial problems is your best defense, but if you find yourself facing money problems, keeping your leadership informed and being open to help can prevent many consequences.

subset: commoncrawl


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Come Home to Montecatini: Eating Disorder treatment in a compassionate, home-like setting
For more than 20 years, Montecatini has been helping adolescent and adult women struggling with eating disorders. In our warm and intimate environment, we provide safe and effective treatment to even the most complex and high acuity patients. Our goal is to return those who choose to heal with us to functional and joyful lives, secure in their own recovery.
You will be contacted by an eating disorder specialist within 24 hours
This organization does not disclose, give, sell, or transfer any personal information about our visitors, unless specifically required for law enforcement or statute.
A Message from Montecatini
"For more than 20 years, Montecatini has offered world class treatment and has been a place of serenity and support for our eating disorder patients. Our staff is comprised of professionals who have extensive experience with eating disorders, both professional and personal." Read more
Our Philosophy
At Montecatini we recognize the tremendous courage it takes to face recovery. We know how difficult this decision can be and we also know the rewards and freedom you will find as you move along in your journey toward recovery with us. We strive to provide a positive, respectful and culturally sensitive environment that will give you "real life challenges" and experiences.
"I want to thank everyone for everything you have done for me. You have changed my life and saved me from myself."
If you are a therapist or professional considering referring a patient for any level of care at Montecatini, it is important that you are aware of our admission process, our treatment programs and services, and our high level of commitment to a collaborative team effort. Your involvement is essential to continuity of care and successful recovery for your patient. Please contact us directly for further information.


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Product Information
- Cars 2 GeoTrax World Grand Prix RC from Fisher-Price
- Part of the Cars 2 brand
- We recommend this product for ages 2 and up
- 6 AAA batteries required TTPM Is Always On With
What It Is
What It Is
High-octane adventure continues with the release of Disney/Pixar's Cars 2 on June 24, 2011. Lightning McQueen and Mater head to the World Grand Prix where they get caught up in international espionage. The World Grand Prix comes to life in Fisher-Price's Cars 2 World Grand Prix R/C playset.
The World Grand Prix R/C playset includes such locations from the movie as the Minion Garage with Easy-Rail Station, Tokyo Pit Stop, Porto Corsa Racing Venue with collapsing bridge, eight pieces of Snap-Lock track with an Acer (one of the Cars characters) push vehicle, and a Finn McMissile Turbo R/C vehicle. The easy-to-use Turbo R/C remote lets kids "drive" Finn McMissile forward and backward along the track. (Finn McMissile even works off the track on hard surfaces.) Finn McMissile also says phrases from the movie.
The World Grand Prix R/C set works with other Cars 2 GeoTrax toys to recreate the excitement of the movie and help kids embark on new adventures. Other Cars 2 GeoTrax playsets, track packs, and R/C cars are sold separately.
Why It's Fun
The Cars 2 GeoTrax line lets kids build their own Cars 2 world. The World Grand Prix R/C set offers lots of fun racing action just like in the new movie. Kids will like reenacting scenes from the movie or creating new adventures for the Cars characters.
Who It's For
The World Grand Prix R/C set is for ages 2—7. It's great for kids who like Cars the movie or for kids who like to play with cars.
What to Be Aware of
Assembly is required, but no tools are needed. It takes about 15-20 minutes to put together.
We really like the design of this, which is easy for preschoolers to operate while giving a really satisfying train experience.
The versatility and the long-term play value of this toy makes it worth the price for parents of Cars fans, particularly since it integrates with other GeoTrax sets.
This set requires six AAA batteries (three for the R/C controller and three for the vehicle), which are not included.
Doc McStuffins Pet Vet Findo Plush
from Just Play
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from Just Play
Doc McStuffins Pet Vet Gabby Plush
from Just Play
Doc McStuffins Pet Vet Whispers Plush
from Just Play
Doc McStuffins Pet Vet Squibbles Plush
from Just Play
John Deere Pick N Pop Foot to Floor Combine
from TOMY
LEGO Duplo Fire Station
from LEGO
Doc McStuffins Pet Vet Checkup Center
from Just Play
Imaginext Power Rangers Goldar and Rita Repulsa
from Fisher-Price
Doc McStuffins Pet Vet Doctor's Bag Set
from Just Play


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Give the perfect children's gift to your - or someone else's - little adventure-seeker. Kids who love playtime, and we know they all do, will love hiding and hanging out in this inviting kids teepee!
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The Santa Clara Senior Center offers a variety of classes that will help meet your fitness goals for 2014. From No Falls S.O.S. (falls prevention) to Fitness for All (chair-based exercises), as well as Dance for Health, and Strength and Conditioning, we offer a spectrum of opportunities for various fitness levels.
We are excited to introduce three class instructors at the Senior Center!
We also offer Introduction to Woodworking for those who have always wanted to learn how to safely use a table saw, router and other tools. This class will provide participants the opportunity for hands-on instruction in the woodshop, as well as help you create a project. The next class begins on March 17.
Registration is currently open for all classes at the Senior Center. Please view the flier or the Recreation Activities Guide for additional class and registration information. For more information, please call the Santa Clara Senior Center at (408) 615-3170.
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Conservation and environmental news & publications: Cameroon
Job Annoucement - Director Communications, Marketing and Fundraising, Africa
Location: WWF office in Nairobi, Kenya.
Elephants in search of safe havens
When I joined WWF-Cameroon in 2006, I was anxious to meet the mysterious creature of the forest, ...
UN chief takes poaching concerns to Security Council
The UN Security Council today will be briefed on the threat to peace and security posed by Central ...
Twenty wildlife criminals arrested in Cameroon
Cameroon arrested twenty suspected wildlife criminals and seized 45 weapons during ...
UN recognizes severity of wildlife crimes
Members of the United Nations Commission on Crime Prevention and Criminal Justice Friday passed a ...
FSC certification in Cameroon surpasses 1 million hectares
Total Forest Stewardship Council (FSC) certified area in Cameroon has exceeded 1 million hectares
Poachers kill at least 89 elephants in Chad
At least 89 elephants were killed by poachers last week in Chad - in one night. Regional ...
Éléphants trouvés morts lors d'un inventaire faunique au Cameroun
Des carcasses d'éléphants trouvés dans le Parc National de Nki dans le sud-Est du Cameroun indique ...
"They are after our elephants"
Fifty kilometers from Chad's border, at the edge of North Cameroon's Bouba N'Djida National Park, ...
Cameroon sends army to defend borders from Sudanese poachers
Cameroon announced Friday it has mobilized its Special Forces units to prevent Sudanese poachers ...


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User Tip: If you're unsure of your vehicle type, you may skip the machine type selection box.
Select type, make, model and year above
"Customer service is priority #1 at Rocky Mountain ATV/MC. We value our customers and strive to be the best shopping experience- when you buy from us, you are buying lifetime service."
-Dan Thomas, CEO and Founder
We take pride in offering no hassle returns. In the event of a return, please call, email or chat with us to receive a solution to the problem. For apparel that doesn't fit quite right, Click here to see our Fit Guaranteed Program.
We will stand behind all products we sell with regards to manufacturing defects in workmanship and material. Most products are limited to the manufacturer's warranty. However, we will do everything in our power to take care of the problem.
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Comments On Aug 04, 2015:rubber is very hard, chain is very loud rolling on it
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Comments On Apr 14, 2015:Works great but make sure to put your own locktite on because the nylon locking nut doesn't hold up against the vibrations.
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Comments On Apr 10, 2015:Went right on my 2000 Honda CR250R. Fit great, quieted right down!!!
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Comments On Apr 01, 2015:seems very well built, and was a perfect replacement for my oem roller
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Comments On Feb 10, 2015:This roller is not the same diameter or width as the original it is supposed to replace. Verified correct P/N for my bike. Did not use it. It's still in my tool box. Will give it away to someone who can use it.
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Comments On Dec 30, 2014:works well, a little smaller than OEM , but haven't noticed it mattering
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When I search, for example, "something label:somelabel" I get 1000 results paginated by 25 (my settings). 'Select all' selects only the 25 on the current page, I would like to delete all of them (1000). How to do it? I guess I could specify a filter to perform this search, delete the messages and apply this filter, but I have many queries and making filters for all would be PITA.
Take the 2-minute tour ×
Web Applications Stack Exchange is a question and answer site for power users of web applications. It's 100% free, no registration required.
You should get a message at the top of the search results that reads;
Hope this helps.
Click on this and you will get what you want.


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Ridley Bikes is worldwide leader in the cyclocross market. This is reflected in the sponsorship of two of the biggest teams in the cyclocross circuit, Telenet-Fidea and Sunweb-Napoleongames. Telenet-Fidea with former world champion Bart Wellens and Tom Meeusens is always in the front of each race. Kevin Pauwels and Klaas Vantornout are the leaders of Sunweb-Napoleongames.
The total amount of victories in modern cyclocross for Ridley Bikes is impressive. 7 World titles, several national titles and wins in all the major series as Super Prestige, GvA/Bpost and the UCI World Cup. An unrivaled track record in cyclocross!
- Telenet-Fidea: www.fideacyclingteam.be
- Sunweb-Napoleongames: www.sunweb-napoleongames.be
- AVB cycling: www.procontract.be


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Thousands of years ago, people spent hours gazing at the night sky. They found that by connecting the stars as if they were dots, patterns emerged that resembled animals, people and things.
Today, we call star patterns constellations. Eventually, 88 star patterns were identified. The patterns helped people navigate on land and by sea as well as tell time, appearing in different parts of the sky depending on the day and year. (The stars don't move. Earth moves, rotating on its axis once every 24 hours and revolving around the Sun once every year.)
Do you enjoy stargazing? Here's help finding the different stars and constellations. (You can also reference star maps on our astronomy links page.)
The Big Dipper
The big dipper is not a constellation, but an asterism (a familiar group of stars located within a constellation). See image to the left (photo credit: NASA/Jerry Lodriguss).
Look for seven major stars: four in the "bowl" and three in the "handle." The two stars on the outside of the bowl are called the "pointer" stars. They point to Polaris, a bright star that is also called the North Star because with it you can figure out which way is north.
To find north:
- Find the Big Dipper.
- Find the pointer stars.
- Find Polaris.
- Look straight up.
- Turn your body towards Polaris.
- Now, you're facing north.
Ursa Major, the Great Bear
If you find the Big Dipper, you have found the Great Bear: The Dipper's handle is the Bear's tail. See the image to the right (credit: NASA/Akira Fujii).
Legends about the Great Bear abound. Ancient Greeks and Romans believed that a mythological king grabbed its tail, swung it around, and swung it into the sky to whirl around the North Pole forever. Some Native Americans believed that the three tail stars were hunters chasing the Bear.
Ursa Minor, the Little Bear
Polaris will help you find the Little Dipper, also known as Ursa Minor, or the Little Bear. Polar is the star on the end of the Little Dipper's handle.
Orion, the Hunter
This is easiest to find in the winter. Look for three bright stars in a line—these are Orion's belt. See image to the left (credit: NASA).
The two stars north of this are Orion's shoulders. One of these is Betelgeuse ("BEETLE-juice"), which is a giant red star. The two brighter stars to the south are his legs.
Ancient people used Orion to predict the seasons: If it appeared at midnight, the grapes were ready to harvest. If it appeared in the morning, summer was beginning. If it appeared in the evening, winter had arrived.
Canis Major, the Great Dog
This is named for the larger of Orion's two hunting dogs (the other, Canis Minor, has only two stars).
To find Canis Major:
- Imagine a straight line through Orion's belt.
- Move your eyes left (south) until you come to a very bright star—that's Sirius, the nose of the dog.
- Look farther south to find a triangle of stars that marks the dog's hindquarters.
Ancient Egyptians called Sirus "the Nile Star" because it always appeared in the sky right before summer began and the waters of the River Nile began to flood. In medieval Europe, people thought that a combination of light from the Sun and Sirius caused the hot and humid "dog days" of summer.
Credit: NASA
On a clear and moonless night away from bright lights, you can see about 2,500 stars. Spend some time looking at the sky and connect the stars!


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|Men's Basketball » News » Schedule » Roster » Coaches » Statistics
Sunday, November 28, 2010
Milligan College no match for ETSU in Thanksgiving weekend matchup
JOHNSON CITY, Tenn. (Nov. 27, 2010) - Scoring 61 first-half points, the ETSU men's basketball team's early offensive barrage was simply too much for NAIA Division II opponent Milligan College, as the Buccaneers rolled to a 103-55 trouncing of the Buffaloes Saturday afternoon inside the ETSU/MSHA Athletic Center.
With the win, the Bucs improved to 2-2 on the year as they prepare for an eight-game road trip that will take them away from Johnson City for over a month.
"This was one on paper that we are supposed to win," said ETSU head coach Murry Bartow. "I saw a lot of good things out there and we needed this one as we get ready for a really tough stretch on the road. Our guys know the next few weeks are going to be a challenge."
The Bucs got a double-double effort from junior Curtis Wilkinson (Bude, Miss.), as the 6-foot-8 forward finished with 15 points and 10 rebounds. Meanwhile, senior guard Micah Williams (Manchester) had a team-high 17 points to go along with four steals, while junior forward Isiah Brown (Miami, Fla.) netted 16, senior guard Mike Smith (Vandalia, Mo.) pitched in 13, and senior guard Justin Tubbs (Trussville, Ala.) added 11.
Junior Adam Sollazzo (Tampa, Fla.) also had a strong night at the point, dishing out 10 assists. As a team, the Bucs enjoyed some efficiency on the offensive end that resulted in 25 assists on 38 made baskets.
In the first half, the Bucs never let the Buffs even think about an upset. Hitting on 69 percent of their shots from the floor, 50 percent from 3-point range, and 79 percent from the foul line, ETSU built an early 10-2 lead and never looked back.
In all, the first half ended with Milligan giving up eight turnovers on five ETSU steals, and the Buffs shot just 23 percent from the floor - 18 percent from 3-point range.
The second half was a little better for the Buffs, as they were only outscored 42-38. However, at that point the Bucs were simply on cruise control.
Milligan got a game-high 18 points from Hudson Fricke.
As a team, the Bucs finished shooting 61 percent from the floor, 47 percent from 3-point range, and 70 percent from the line. They out-rebounded the Buffs 41-31, and held Milligan to just 30 percent shooting from the floor.
In the paint, ETSU outscored Milligan 54-14, and enjoyed a 40-21 edge in bench scoring.
The Bucs will return to action on Wednesday, Dec. 1 at Dayton. Game time is set for 7 p.m. For more on ETSU men's basketball throughout the season, visit ETSUBucs.com and click on the men's basketball link.
Men's Basketball Archives
2010-11 Men's Basketball


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Which Big Challenges Will You Tackle in 2013?
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Sell More Cloud with the Updated Cloud Sales Guide for IBM Business Partners
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If you haven't used IBM's Cloud Sales Guide lately, you should really check it out. The Cloud Sales Guide, which was just refreshed with new content in June, is an easy-to-use digital reference guide that covers the breadth of IBM's cloud solutions offerings. The guide is great for cloud ... [ + Read more ]


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The Institute of Local Government Studies (INLOGOV) is the leading academic centre for research and teaching on local governance and strategic public management. We enrich the world of local public service with research evidence and innovative ideas, making a positive difference.
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The Lantern Corps Rainbow Gets Colorful Carvings for Halloween
While Grace Belancik (a.k.a. DeviantArt user RocketGirluvsUkitake) flies her comic book fan flag all year long, this Halloween she's letting her colors shine in full force with a full lineup of multi-food jack-o'-lanterns bearing the emblems of DC Comics' lantern corps.
Belancik took a trip to a pumpkin farm and a local grocer to obtain her base ma


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Check Up Event - Safe Kids Portland Metro - 1/18/2014 - 10:00AM-1:00PM
No appointment necessary, drop in between posted hours. To ensure correct installation and faster service, please read and bring your car seat instructions and vehicle owners manual. A certified technician will help parents and caregivers learn to install and use their child restraints properly. Each car seat check will take about 40 minutes.
Saturday, January 18, 2014 - 10:00am to 1:00pm
WhereAmerican Medical Response
9800 SE McBrod
Milwaukie, OR


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PMC Presentations at Surrey Services for Seniors
Penn Memory Center clinicians will speak at Surrey Services for Seniors on the third Fridays in the months of February, March, April, and May 2015. Talks will include an overview of brain aging, a discussion on diagnosing memory, healthy brain aging, and caregiver issues.
Surrey Services for Seniors is a non-profit organization offering comprehensive resources, services and activities in Broomall, Devon, Haverford and Media, PA. Their mission is to help older adults live at home with independence and dignity and continue as active members of the community.
Please register for these lectures online at http://surreyservices.org/events/penn-memory-program-alzheimers-dementia-overview.
Following is the schedule of talks that Penn Memory Center clinicians will deliver:
Friday, April 17, 2015 from 9:30 a.m.– 11:00 a.m.
Cognitive Aging and Cognitive Fitness: a Proactive Approach, Dawn Mechanic-Hamilton, Ph.D.
How can we maximize our cognitive health as we age? We will review the changes expected with typical aging and how we can use compensatory strategies and changes in behavior to maintain cognitive health.
Friday, May 15, 2015 from 9:30 a.m. – 11:00 a.m
Caring for the Dementia Caregiver: Promoting self-care to achieve better outcomes for the person with dementia, Felicia Greenfield, LCSW
Family caregivers of people with dementia are at increased risk of adverse health including increased stress, anxiety and depression. Self-care for the caregiver is essential for improving not only the health and well-being of the caregiver, but of the person with dementia as well.
The Penn Memory Center will have information about programs, services and research participation on site.
Lectures are free to the public and are held at:
Surrey Services for Seniors
60 Chestnut Avenue
Devon, PA 19333
Please register for these lectures online at http://surreyservices.org/events/penn-memory-program-alzheimers-dementia-overview.


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I actually wish they didnt pick us. Florio is the biggest douche there is. Taking a shot by saying Miami wins close because Amendola is out. We would have won with him playing anyways - Smith would have shut him down easily.
Rams at Dolphins
MDS's take: Hardly anyone has noticed it, but the Dolphins' defense is actually quite good. Miami will put a lot of pressure on Sam Bradford and win a low-scoring game.
MDS's pick: Dolphins 14, Rams 10.
Florio's take: Arguably the best game of the weekend, Rams coach Jeff Fisher gets a shot at the team he spurned. With tough defenses and underrated offenses, the Miami offense should be able to do more against the St. Louis defense than vice-versa, given the absence of Danny Amendola.
Florio's pick: Dolphins 14, Rams 12.


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Entrepreneurship is about vision and passion. New ideas that change industries. In 1967, Herb Kelleher founded Southwest Airlines. Prior to this, flying was a luxury and only those that were wealthy or traveling for business used airplanes. With the start of Southwest Airlines, the industry changed. Today, Southwest Airlines is still one of the most profitable airlines. Herb's entrepreneurial vision and smarts are reflected in the Center, both in name and spirit.
The Herb Kelleher Center for Entrepreneurship Growth and Renewal is not just about new ventures, it's also about teaching, learning and researching entrepreneurship and business enterprise. The entrepreneurial research done at McCombs, by both McCombs faculty and faculty around the university enables companies in Texas and the nation to improve their course of action, advance company growth with more effective preparation and initiate renewal in mature companies that would otherwise fail.
Thomas W. Gilligan, Dean, McCombs School of Business
For decades, value creation through innovation and entrepreneurship has been a dominant and consistent focus of the McCombs School of Business. McCombs is situated in a university with considerable assets in innovation and creativity. Courses on innovation and creativity can be found in at least eight other colleges at the university. McCombs has a significant research and teaching presence in these important areas as faculty in all academic departments teach and conduct research on creativity and innovation.
The international reputation in entrepreneurial studies that McCombs has had for years will only keep growing as we continue to foster innovation and new business creation. At the forefront is one of the most influential academic research units in this area, the Herb Kelleher Center for Entrepreneurship.
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October 15, 2011 at 10:30am to April 21, 2012 at 11:30am – Foundry Art Centre "Mini Masters" is a beginning art experience for preschoolers ages 3-5 on the third Saturday of every month. Each class offers different activities that combine stories and instruction to inspire the… Organized by Foundry Art Centre | Type: mini, masters, preschool, art, classes
December 23, 2011 at 6pm to February 24, 2012 at 9pm – Hayloft Gallery Come view new works by artist Derek Gollaher at Hayloft Gallery in Historic Sainte Genevieve, Missouri. Open reception is Dec 23 6-9pm. Come enjoy wine and art with us during this holiday season. … Organized by Derek Gollaher | Type: art, exhibit
January 6, 2012 at 11am to February 19, 2012 at 4pm – South Hamptom (SoHa) neighborhood Zurick Looped contrasts video and film at the Soha Gallery, 4915 Macklind, from January 6 through 19, with an opening night celebration from 6 to 9 on the evening of the 6th. Three installations are… Organized by Julie Malone for R D Zurick | Type: video, installations, &, wall, hangings
January 14, 2012 at 6pm to March 10, 2012 at 9pm – The Vino Gallery Join us at The Vino Gallery on the evening of Saturday, January the 14th, for the opening of Urban Landscapes and Holy Places. Our featured artist will be Jennifer Richter. We will also feature artwo… Organized by The Vino Gallery | Type: gallery, opening
January 14, 2012 at 6pm to February 29, 2012 at 7pm – Soulard Art Market Call for Art — "Carnivalesque" The Soulard Art Market (SAM) and Contemporary Gallery is calling for submissions to "Carnivalesque" a juried exhibition of any medium. The show runs from March 8, 2012… Organized by Soulard Art Market | Type: call, for, art
January 19, 2012 at 4pm to April 5, 2012 at 5:15pm – Foundry Art Centre Designed for grades 6 – 12, these all media classes will have students working in a variety of mediums during this 12-week session. Drawing, painting, and some sculpture – the class will explore many… Organized by Foundry Art Centre | Type: foundry, art, centre, youth, all, media, classes
January 19, 2012 at 6pm to March 17, 2012 at 5pm – Clayton "Sound and Vision" Exhibition SeriesOpening Reception: Friday, January 20th, 2012; 6pm–8pmExhibition Dates: January 20th, 2012—March 17th, 2012CLAYTON—The St. Louis Artists' Guild is pleased to annou… Organized by St. Louis Artists' Guild | Type: art opening
January 20, 2012 at 6pm to February 25, 2012 at 10pm – Good Citizen Gallery Mike Calway-Fagen The Indeterminate Length January 20 - February 25, 2012 Opening Reception Friday, January 20, 6 - 10 PM Closing Reception and Catalog Release Saturday February 25, 6 - 10 PM Goo… Organized by Good Citizen Gallery | Type: gallery, exhibit, and, opening
January 27, 2012 at 6pm to March 4, 2012 at 4pm – The Saint Louis University Museum of Art Experience the African-American journey through the brush strokes of two noted painters: Father James Hasse of the Society of Jesus and Judge Nathan B. Young. Spirit and History: Paintings by James H… Organized by Mary C. Marshall | Type: art, exhibition
February 1, 2012 to February 25, 2012 – Componere Gallery in the Delmar Loop Artists: Kay Pick Zivkovich, Design Professor and Assistant Director, School of Art and Design, Southern Illinois University-Carbondale (SIUC); Cortney Boyd, Visiting Assistant Professor in Glass, SI… Organized by Componere Gallery of Art | Type: exhibit:, monoprints, glass, &, wood
February 1, 2012 to March 30, 2012 – Comprehensive Chiropractic & Studio Gallery CANDLE LIGHT: Acrylic on canvas, drawings and prints by Bulgarian American artist, Galina Todorova. Exhibiting January 6 through March 31, 2012 at Comprehensive Chiropractic and Studio, 113 West 5th… Organized by Jane Ollendorff | Type: art, exhibit, &, reception
February 3, 2012 at 6pm to February 24, 2012 at 8:30pm – Crossroads Hospice 2380 Schuetz Rd St. Louis, MO 63156 314-801-6960 www.Crossroadshospice.com You are cordially invited to an artist reception at Crossroads Hospice "The Art of Living" Friday, February 3rd 2012 at 6:00-8:30pm Crossroads Hospice 2380 Schuetz Rd St. Louis, MO 63156 314-801… Organized by Crossroads Hospice | Type: "the, art, of, living"
February 7, 2012 at 5:45pm to April 3, 2012 at 7pm – Foundry Art Centre Designed specifically for art teachers, these fun workshops are full of hands-on activities to take back to your art classrooms. With over 30 years of elementary art instruction experience, instructo… Organized by Foundry Art Centre | Type: teacher, enrichment, workshops, art, teachers
February 10, 2012 at 5pm to April 15, 2012 at 4pm – The Saint Louis University Museum of Art Drawn from the Saint Louis University Museum of Art's permanent print collection, the exhibition examines dissent expressed by artists of various periods and cultural backgrounds. Selected artworks i… Organized by Mary C. Marshall | Type: art, exhibition
February 19, 2012 from 2pm to 3pm – William and Florence Schmidt Art Center Help us celebrate the Schmidt's 10-year anniversary with "Art." What constitutes art? Watch a performance of "Art," a three-person play about a conversation between an art collector who has spent a l… Organized by Schmidt Art Center | Type: play


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Overview The University of Rhode Island Institutional Review Board (IRB) reviews research projects which involve human subjects to ensure that two broad standards are upheld: first, that subjects are not placed at undue risk; second, that they give uncoerced, informed consent to their participation.
With representation from a wide range of scientific disciplines and from outside the academic community, the IRB gives individualized attention to the numerous research projects at the University.
Protocol Review Process The length of the approval process is influenced by several varying factors, such as the complexity of a protocol, the risk of the project to the research subjects, and the completeness of documentation. In all circumstances, early submission combined with accurate documentation will result in an expedited approval.
The IRB application process starts with your submission of the application form, consent forms and other required appendices/materials. The ORI staff pre-reviews your application to make sure all of the necessary materials are there for IRB review. The ORI staff will contact you by email if your application or forms are not sufficient and will let you know what needs to be done to get your application ready for review by the IRB.
Applicants must submit application materials to the IRB at least three weeks prior to the date of the scheduled IRB meeting for all protocols that must be reviewed by the fully convened IRB. Please allow at least 6-8 weeks for protocol review, depending on the complexity of the project, the risk of the project to the research subjects, and the extent of revisions required.
IRB Meetings Schedule
General Guidance
• Does My Research Need IRB Review?
• Protocol Review Process Flow Chart and Guide
• What to include in my IRB submission package
• Does My Research Qualify as Exempt Research?
• IRB Meet Schedule and Submission Deadlines
• URI IRB Protection of Human Subjects Policies and Procedures
• For assistance, contact Mary Riedford (firstname.lastname@example.com or 874-4813) or the main Research Integrity Office: 874-4328.
Submission Process and Forms
The Initial Review of Human Subject Research (Initial IRB Application) is required for all research that requires a human subject component (exempt, expedited, and full convened IRB review). What you will notice immediately is the there are many appendices to the Initial IRB Application. Most Principal Investigators (PIs), will seldom use beyond a handful of these. These forms have designed to streamline the review process so all information required for review is submitted at time of application. Our hope is to decrease the review time for researchers.
All information must be submitted through IRBNet. Refer to the link below for required forms and sample documents.
Human Subjects Research Training
• Guidance for Student Researchers
• Students as Research Subjects


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If you can dream it, you can do it. -Walt Disney
Quality is a great business plan. -John Lasseter
Let's make some funny pictures. -Tex Avery
I never considered a difference of opinion in politics, in religion, in philosophy, as cause for withdrawing from a friend. -Howard Zinn
When critics sit in judgment it is hard to tell where justice leaves off and vengeance begins. -Chuck Jones
And what do you benefit if you gain the whole world but lose your own soul? -Jesus
A man should never neglect his family for business. -Walt Disney
What's most important in animation is the emotions and the ideas being portrayed. -Ralph Bakshi
Once you have heard a strange audience burst into laughter at a film you directed, you realize what the word joy is all about. -Chuck Jones
Before enlightenment: chop wood, carry water. After enlightenment: chop wood, carry water. -Buddhist Proverb
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crowd funded studio? can it be done?
Share your views on the state of the Animation Industry.
12 posts • Page 1 of 1
crowd funded studio? can it be done?
Something that I have been thinking about for a long time is if some one could be successful, with an entirely crowd/ fan supported budget create a movie or series. But here is the catch! No hollywood, no theatrical releases, just straight to the internet. Now I know that people do this alot as fan short films or short films. But I am talking about major productions.
Now this is how I would think it would work from a funding stand point:
1st: come to the public with at least 2-3 ideas with concept art. Then let them choose the project they want to see developed the most.
2nd: take it to a crowd funding site. This would be kickstarter and other similar sites. These sites also help keep track of who has supported you so they can get their kickbacks.
3rd: keep your audience involved in the production. The people that funded your project get access to video blogs, and other goodies through out production.
4th: advertise like hell on the web or other media. There would be a lot of social marketing, and maybe a few TV spots if the budget can support it, but mostly the advertising will be on forums, sites like Deviant Art, Youtube, and Vimeo. This money would have to come from the crowdfunding.
5th: Publish your film/series on Youtube or Vimeo Monetize your videos. This can be done with either commercials or required payment before viewing. People who paid to support your project get free access. Also, merchandise out the product to help generate more income.
6th: get your product on DVD and Bluray and set for sell Allow people to purchase your product, but not only hard copies, but on multiple platforms. This would only be done after the project has had a long enough run. Almost like being in a theater, before coming out on video.
Now all the funding that is generated from the monetizing and purchases of videos can be used for future projects to make them bigger and better, to get the initial funding needed for initial development.
I have been tossing this idea around in my head for a while, but I am sure that I am not considering something, or maybe multiple things, and wanted to get the communities opinion of it. Do you think this is doable? how would you do it? and is this something that you could get excited about?
Re: crowd funded studio? can it be done?
Hello there Jquinn!
Is it doable? Absolutely!
Here's what I've observed after a couple of years of studying crowdfunding campaigns and promoting them on AN...
Just because you get something together and put it up on Kickstarter or Indiegogo, it doesn't mean you'll automatically be successful with it. There's several key factors involved.
First, it's very helpful and very advisable to spend plenty of time building your community. Having an audience that you can go to with a campaign is vital. Case in point... Homestuck which had huge success in 2012. They raised $2,485,506 from more than 24,000 backers. The online comic had been going on for some time and had an extensive fan base to appeal to. Even though few if any in the animation biz had heard of this property, they had an extensive fan base that supported them with dramatic results.
Second, be realistic with what you're attempting to achieve through crowdfunding. Don't shoot for a huge amount of money that is beyond what your base can provide. Go to the modest side of things. That will improve your chances of realizing your financial goal. If you exceed it, it will make your campaign look that much stronger and more importantly, you'll have money to work with.
Third, have a project that will compel people to join in and back you. That includes good rewards that you can provide for those that do support your campaign.
Also, don't hesitate to promote! Get the word out there! Build your network, your online presence, email database, social media outlets, etc. The more people are aware of what you're doing the better your chances of crowdfunding success.
These are a few suggestions based upon what I've observed.
Crowdfunding is the way of the future. Anyone thinking in terms of creative independence should by all means be incorporating the option of a campaign into their plans.
Be patient and productive. Develop your property and your audience. Get a quality project together than can migrate to a rewards based system and you'll be in business.
All of my long term plans involve crowdfunding. I'm getting projects together which I'll be launching soon and they all include a crowdfunding aspect to them. A lot of people have been very positively affected by this new system. For years I've discussed the idea of an Independent Economy for artists and this is it! Crowdfunding is here to stay. Make the most of it and have fun.
Good luck and Keep Creating!
Re: crowd funded studio? can it be done?
I agree. Most,if not all, I plan on doing. I am curious to see how people would react to such a business model. It would give the audience so much more input, and involvement with the process.
There are so many situations where fans get mad that a movie is getting made a way that it is, or that some studio is taking a IP and trying to convert it to the big screen. Studios push through this of course, and try to make the film any ways. There is also, a lot of really bad films coming out recently that have no originality. Of course, what I have explained beforehand will not prevent that. But I hope that the community will be able to drive the production towards the idea that they would be the most excited to see. I am going to have to start small and see how it works with the online community reacts to it.
I just need to rally the support for it.
Re: crowd funded studio? can it be done?
This is an unprecedented time in the history of entertainment. We're emerging into an era in which Hollywood becomes increasingly obsolete as to whether a project succeeds or moves forward.
It's all up to you and to me and to each of us as individuals and collectively. If you're set upon becoming a creative force this is your chance.
This isn't a cake walk or a sure thing. It's a chance to show the world what you've got and what you've got to say. If you get something together and communicate effectively as to what you're trying to achieve you'll find success through crowdfunding.
A lot of independent artists and studios are getting financed by their fans. There's no reason why you can't do the same thing.
Re: crowd funded studio? can it be done?
I would love to hear more from the community on this idea. What do you think about tuning in every week for a series on Youtube or Vimeo? both can stream to your mobile devices or have apps for Tvs. Would you watch something like this? You are probably saying: "it depends of the content. I am not watching a 'clueless' TV series". I won't judge you. What kind of series would you watch?
Re: crowd funded studio? can it be done?
What do you want to create? What can you have fun with and can get into. If you're enjoying what you're creating it will show and people will be attracted to your content.
If you go to a seminar about what executives in animation are looking for you'll get their formula. For example Disney would want teenager high school based shows. Cartoon Network has their range and so does Nick.
The era we're in is about going beyond the mainstream. Create something that will make you happy and you can get excited about. Then share it and keep creating and sharing.
Re: crowd funded studio? can it be done?
I have many projects that I would love to start working on. I have a horror series, a short kid film, a couple Sci-fi stories, and a massive fantasy/scifi epic.
I realize there is a formula, but, This would have to be a project that the community wants. I would like to start working towards creating one of these series, but want to see which one the community would be interested the most in to start there, or if they have a specific genre or something that seems to catch their eye.
I suppose, as I am writing this, that I would have to do like what I originally posted at the beginning of this thread and simply create the material to show the projects to the community and have them rally behind the idea they like the most.
Re: crowd funded studio? can it be done?
This is all interesting and good information. I think one of the main hurdles is getting a following. It seems that is done using social media. It is a daunting feat. I would be interested to know if anyone has tips for using social media to its fullest without spending hours a day.
Re: crowd funded studio? can it be done?
I have a friend who is the marketing director for a company, and he says to get the best results, really requires a great deal of time and effort. But, social media is such an organic thing, that it can help things explode fairly quickly, if used properly. It is my hope that this is one such thing that people can get excited about.
However, social marketing is not enough, SEO will still be required, and word of mouth. Which is another reason I say that this has to be a team effort.
Re: crowd funded studio? can it be done?
Your friend is right Jquinn. It takes time and a lot of work to be positioned for a successful campaign along the lines of what you're talking about.
The essential element is your content. And it starts with you. Move towards developing your creative content first. Write it out and draw it even if you're not that good at drawing. At least you've got something happening with it.
The most successful campaigns are those that have developed an audience / fan base over time. This is a long term project that you're on. Keep that in mind and stay focused on your goal and you'll be on the path.
Take intop consideration this project that's currently on KS called GaMERCat.
https://www.kickstarter.com/projects/ce ... rcat-plush
It's made $47,000 so far in just 6 days. Surpassing its $8500 goal in just 5 hours. The comic has been online since June 2011 so that's 2 1/2 years of momentum that the author has developed that's paying off for her.
Exciting times guys!
I'm working on something that will be out soon. My plan is to move towards a KS campaign once the audience develops. The amount of content I've built up is vast and I can publish material for several months before I go to crowdfunding.
In any case, it's great to be creating in a time where we have these options!
Re: crowd funded studio? can it be done?
I agree. I don't want this project, the creation of this crowd funded studio, to be something that is rushed into. Rome was not built in a day. I know everyone wants to have that explosive growth, and amazing story of triumph. However, we must be realistic.
I am currently working to gather a team of artists together to develop some of these ideas, and to encourage the community to do the same for their ideas. the greatest thing I can think of is this Studio taking people from the community and making better artists from them while developing great content for the community to inspire more great content.
This plan has to revolve around word of mouth, social media, and a little bit of injected marketing. Organic growth is the best, since it shows how powerful your ideas is and how well it resonates with your audience.
At this point, I just need people excited about the idea, and have a passion to see it come true. I am an artist, an animator, a designer and so much more. But, I need to be a marketing expert, a social media guru, a blogger, a video blogger. To be realistic, I can't be everything that a studio will need to be successful. This project is more than just creating content, and cannot be bore on the shoulders of the content creators alone. It will need to have people who know how to get the word out, and communicate with the audience in a knowledgable way.
If you, or some one you know is interested in helping try to create something amazing. send them my way.
Re: crowd funded studio? can it be done?
Oh indeed this is doable. It happens every day!
There's an art and science to successful crowdfunding and I have been studying. I work with marketers around the world and these people have their A Games on!
Getting those secrets takes time as many charge for tutorials and guidance, however there are just so many tricks to be played when you apply the winning procedures.
Kickstarter, Indiegogo, Go Fund Me, are the leaders in crowdfunding but they're just a small number of the global crowdfunding companies out there as new ones emerge globally every week. You can join a crowdfunding site in France, Spain, Russia, China, Japan and more.
I would love to bump heads with Charles on this to get a real 1-2-3 procedure.
12 posts • Page 1 of 1


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A Mechanicsville man was killed Monday night, police report, when he tried to walk across a highway in the path of a pickup truck.
Roland Philip Tucker, 52, died at the scene of the 7:55 p.m. accident, according to the St. Mary's sheriff's office. Tucker was attempting to cross the southbound lanes of Three Notch Road, near an intersection with New Market Turner Road, the sheriff's office reports, and he failed to yield the right of way to the 2011 Ford F-150 truck operated by Paul Downs of California. No other injuries were reported.
Neither alcohol nor other drugs, or the truck's speed, are considered to be factors in the accident, according to the sheriff's office.
The sheriff's office has requested that anyone with information on the accident contact sheriff's Cpl. Brian Connelly at 301-475-4200, ext. 9010.


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Arts & Life
A 'Witch Queen' Who Casts Her Spells Year-Round
Originally published on Fri November 2, 2012 3:53 pm
Lady Rhea is not the kind of witch you'll find in a pointy hat this Halloween. She is a real workaday witch, grinding out a living selling magic products in a booth at Original Products, a grocery store-sized botanica in the Bronx. She's been a practicing Wiccan for nearly four decades, making her one of the longest-serving high priestesses in New York City.
"I am a Wiccan high priestess and Witch queen," she says. "My age — I've been in the craft since '73. I have a lot of coven people and people who are attached to me over the last years, so one of them coined me 'Pagan Mother.' Call them up and I'll say 'Hello, are you listening? This is Pagan Mother, call me.' "
This week, Lady Rhea will see a small increase in Halloween-related sales, but most of her clients come looking for the same things that have kept her in business all these years: money, luck and love.
"Some of the requests I get are for love," says the high priestess, whose birth name is Aurelia Bila. "Or, you know, come-to-me candles."
A lot of customers want their boyfriends back or help losing weight, Lady Rhea says, but others want help with money. "They gotta get that dollar going, it's a tough area."
At her booth, people can buy cascarilla, camphor, candles, crystals, frankincense and $40 spell kits.
"This is a museum in itself. You have people asking for a bath. ... Pompeia water, which is an old perfume. Yeah, walk into Macy's and tell them you want Pompeia cologne," she says. "This is a practice, it's an earth religion and so we are a very earthy people. I will not look at a pigeon and consider it a flying rat, I will consider it a creature of the sky father."
Today may be Halloween, but you won't find Lady Rhea in a pointy black hat. She's a real workaday witch who prefers a sweatshirt and Bluetooth earpiece. A practicing Wiccan from the Bronx, Lady Rhea has for nearly 40 years cater to those looking for help in matters of money, luck and love.
LADY RHEA: Hello, Magickal Realms. Lady Rhea speaking, how can I help you?
Some of the requests I get are for love.
You want a love bath?
UNIDENTIFIED WOMAN #1: Yes.
RHEA: OK, come.
Or, you know, come-to-me candles.
UNIDENTIFIED WOMAN #2: And the man becomes crazy about me?
RHEA: Yup. Get my boyfriend back.
UNIDENTIFIED WOMAN #1: You know how to use it. Right, Mama?
UNIDENTIFIED WOMAN #2: I do.
RHEA: Take a normal shower and pour it from your neck down, and pray for love to be resolved.
RHEA: Like Venus standing under a waterfall.
Help with money. They got to get that dollar going. It's a tough area.
The pictures I can't bless.
RHEA: They'll get wet.
I am a Wiccan high priestess and Witch queen. My age, I've been in the craft since '73. I have a lot of coven people and people who are attached to me over the last years, so one of them coined me Pagan Mother. Call them up and I'll say hello, are you listening? This is Pagan Mother, call me.
RHEA: To bless the candle, we carve a hexagram on the top. Thank you, my lady. We carry baths, crystals, and these are our spell kits behind you, $40 per kit. Frankincense, camphor, cascarilla. We have Fast Money. I have a weight loss candle.
This is a museum in itself. You have people asking for a bath with Pompeia water, which is an old perfume. Yeah, walk into Macy's and tell them you want Pompeia cologne.
Hi, sweetheart. How are you?
This is a practice. It's an Earth religion, and so we are a very earthy people. I will not look at a pigeon and consider it a flying rat. I will consider it a creature of the Sky Father.
Comes to 15.24, honey.
RHEA: I'm the city witch.
UNIDENTIFIED WOMAN #3: Thank you.
RHEA: You're welcome.
CORNISH: Lady Rhea runs Magickal Realms, a Wiccan shop in the Bronx, New York. Our story was produced by Matt Ozug for the project Faith in the Five Boroughs. To see a video of Lady Rhea, visit NPR.org.
CORNISH: This is NPR. Transcript provided by NPR, Copyright NPR.


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As much as I enjoy Blue Bloods , there are cases that leave me with more questions than answers. " Domestic Disturbance " was one of those episodes. For those who aren't aware, October is National Do More »
Blue Bloods "Domestic Disturbance" Season 3 episode 2 airs Friday Oct 5, 2012 (10:00-11:00 PM, ET/PT) on the CBS Television Network . Episode Synopsis: When an injured woman recants her claim of dom More »


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About LIM College
LIM College Adding More Space at Maxwell Hall
New "community center" of the College will include an eatery, more seating and docking stations
LIM College is adding 4,500 square feet of new space to its Maxwell Hall location (at 216 East 45th Street). The College is taking over the street-level area directly adjacent to Jittery Joe's Coffee and the existing student lounge.
Construction started at the beginning of October. When completed, the space will house an expanded lounge with new furniture and more seating for students, and the entire floor's audio-visual capabilities will be dramatically enhanced with the integration of a state-of-the-art audio-video projection system. Electric docking stations will also be added throughout both sides of the student lounge, supporting the LIM College community's ability to "BYOD" -- bring your own mobile device -- for educational or recreational use.
With student relaxation and socialization as its primary purpose, the first floor of Maxwell Hall will become the community center of the College – serving as a venue for special events, while serving students, faculty, and staff on a daily basis. To help achieve the goal of creating a "student union" for LIM College, the Office of Student Life will also move to newly-constructed offices on the lower level of Maxwell Hall.
A particularly exciting aspect of this expansion will be the addition of a food vendor that will offer a wide variety of all-natural and organic items, including wraps, salads, soups, snacks and drinks. They will have a storefront entrance as well as an interior window exclusively for LIM College use.
The new space is expected to be ready for use by the beginning of the Spring 2013 semester.
Says Elizabeth S. Marcuse, President of LIM College, "We are very excited to complete this addition and, as always, remain committed to providing our students, faculty, and staff with the best facilities and resources possible."


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"I saw many tombs and pyramids in Egypt, and also went to Jordan, Lebanon, Syria, Israel, and Palestine. Most rewardingly, I also tried to get involved in the community. I taught and tutored English to refugees. My students were always prepared and eager to learn, and I learned more from them than I could have ever taught them." —Sara Rose Bobak '10
SU Abroad consistently ranks among the highest quality international education programs in the United States. More than 2,000 students from both Syracuse University and colleges across the country study abroad with SU every year. SU Abroad programs foster scholarship in action through a combination of world travel, academic excellence, internships, and community collaboration. Syracuse University offers many opportunities for students to spend time studying and experiencing the culture of the Middle East.
In addition to other centers in Beijing, Florence, Hong Kong, London, Madrid, Santiago and Strasbourg, Syracuse University currently operates the SU Istanbul Center at Bahçeşehir University in Istanbul, Turkey.
Students may also study in other Middle Eastern institutions of education through the World Partners program. Among the institutions from the 20 additional countries available to SU students through the World Partners program are American University in Beruit, AMIDEAST Program in Morocco, Tel Aviv University in Israel, Bogacizi University in Turkey and American University in Cairo, Egypt .
The Maxwell School of Citizenship and Public Affairs and An Najah University in Nablus, West Bank have partnered to facilitate academic cooperation and promote mutual understanding. In preparation for establishing a formal framework for future activities, both partners will encourage units to explore the feasibility of activities such as student exchanges and faculty exchanges for instruction, research, lectures, and discussions that mutually benefit both institutions.


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The "rules and ritual" business was brought by robertk as a defense of his wholesale rejection of sitting meditation practice.Dan74 wrote:retrofuturist wrote:Greetings Dan,Dan74 wrote:In a sense what you term rites and rituals can serve as a bridge between meditation and "everyday life" in that it is easier to bring a spacious clarity of meditation into a well-rehearsed activity like that than to face the "darts and arrows" in the same spirit.
Of course there are many other good reasons for performing them too. But since we are on the subject of meditation...
Well actually, the topic is about "the causes for wisdom".
Paul, I am probably not in the mood for your sense of humour but people were discussing rites and ritual - so why the seemingly smartarse comment?
Also, as has been mentioned above in response to robertk's comments, even if someone starts out the sitting practice with the hindrance of "rules and rituals," that does not mean they are going to be forever stuck there. Insight into what binds is part of the natural unfolding of practice. It is why one does sitting meditation practice.retrofuturist wrote:Since "attachment to rites and rituals" (as compared to say, "absence of meditation") is one of the three fetters that binds us to avijja (ignorance) and prevents stream-entry, possibly it's a more important (and less beaten to death) subject of discussion on a topic addressing "the causes for wisdom".
And here you go!
If someone is performing a ritual, does it mean (s)he is attached? And if so, could it still be useful before stream-entry?
Dan wrote:retro wrote:The topic, and forum in general, needn't always be framed as a relentless defense of sitting meditation and people's chosen practices (as it has been for much of the last 18 pages of discussion).
A long time ago I was debating with Tilt, unable to understand his seemingly vehement attack on Mahayana sectarianism and particularly the term "Hinayana". Then he shared that due to this sectarian propaganda, to effectively slander, the avenue of exploring Theravada remained closed to him for some time. In essence he was denied an opportunity to explore this amazing tradition. A travesty, wouldn't you agree?
I think all ill-informed attacks on a tradition, a lineage or practice, do precisely that - misinform and deny people an opportunity to explore through slander. I am not defensive about my chosen practice - you are reading me entirely wrong. After 10 years I am completely at home with it. Any inadequacies are my own. But I think it is a good idea to correct misinformation and sectarianism when we see it. I try to do the same within my chosen tradition too.


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28 Cringeworthy Fashion Moments We Witnessed on Laguna Beach
Laguna Beach and The Hills: Where Are They Now?
18 Important Life Lessons You Learned From The Hills and Laguna Beach
Relationship Reality Show Stars: Now and Then
Heidi Montag Tearfully Calls Out Lauren Conrad For "Ruining Her Life"
19 Times Kristin Cavallari Was Wonderfully, Hilariously Unapologetic
Lauren Conrad and Stephen Colletti Have an Epic Laguna Beach Reunion
Which Friendships Survived Laguna Beach and The Hills?
Relive Prom's Highs and Horrors (in GIFs)
What If The Hills Ended Like Gossip Girl? It's a TV Finale Mashup!
Top 5 Most Talked-About Stories: The Laguna Beach Cast, Busy's Baby Name, and More!
Blast From the Past: The Casts of Laguna Beach and The Hills


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EdS in Educational Leadership
Schools are facing a critical shortage of administrators. An EdS in Educational Leadership from Webster University will build on your teaching, curriculum, and support services background and encourage you to think outside the box, seek solutions to challenges in schooling to make the world different, and find the courage to do what is best for all students.
It is an ideal way to earn an advanced degree while preparing for the state assessment. Coursework, research, and internship experiences prepare you for positions of greater responsibility and influence.
The EdS is offered with three areas of emphasis: educational leadership, school systems superintendency and leadership, and technology leadership. It can be earned in 33 credit hours and in two and a half years, if you attend one class per term.
Students wishing to combine the EdS program with the certification program must work with their advisor and EdS faculty to meet certification requirements and document performance. Students in the school systems superintendency and leadership major can work toward a superintendent certificate. After successful completion of state-required assessment activities, students can apply for administrative certification.
Points of Distinction
- Webster University's worldwide context provides insight on global teaching advancements and techniques.
- Webster University's WorldClassRoom offer courses and programs that you can participate in any time of day or night; from anywhere you have a computer with Internet access, such as work, home, or the library.
- Faculty work on the leading edge of school administration and lead by example, promoting creative thinking to advance the quality of education for all students.


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The News-Sentinel selected the 32 finalists and now it is up to you, the reader, to determine who should be the News-Sentinel Fan Choice High School Football Area Player of the Year.
The News-Sentinel Fan Choice Player of the Year recognizes the top individual performances from Fort Wayne area players during the regular season and gives fans the opportunity to decide who was the best player.
The five-round tournament begins Monday with all four regions' first-round matches. Online voting for these 16 first-round matches will end at 11 p.m. Monday. The winners will advance to the regional semifinals on Tuesday.


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Sheet Straps Hold Sheets in Place All Night
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slippery sheets I have a friend who recently began sleeping in a hospital bed at home. The mattress is slick and the bottom sheet wouldn't stay on. I finally remembered using the sheet straps in the past, so I got on the Internet and found you. Great product! Our problem was solved immediately. Thanks July 24, 2013
Plastic, not metal Service excellent as usual. I was hoping the end "catches" would be metal as the plastic is difficult to get to hold tightly. With the underside raised portion being plastic/rubber too, the plastic open catch frequently is not sturdy enough to hold. I ordered them hoping for the best as these little straps are difficult to find. Thank You August 17, 2012
They really solve the problem These really do the trick! They hold either sheets or mattress pads so they don't slip off. Of course, Vermont Country Store would have them! August 7, 2012
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Late stage assay provider results from the probe development effort to identify inhibitors of PME-1: fluorescence-based dose response cell-based gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of ABHD10
Name: Late stage assay provider results from the probe development effort to identify inhibitors of PME-1: fluorescence-based dose response cell-based gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of ABHD10. ..more
Related BioAssays
Related BioAssays
BioActive Compound: 1
Related Experiments
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC)
Center Affiliation: The Scripps Research Institute (TSRI)
Assay Provider: Benjamin Cravatt, TSRI
Network: Molecular Libraries Probe Production Centers Network (MLPCN)
Grant Proposal Number: 1 R01 CA132630
Grant Proposal PI: Benjamin Cravatt, TSRI
External Assay ID: ABHD10_INH_FLUO_GELBASEDABPP_3XIC50_INSITU
Name: Late stage assay provider results from the probe development effort to identify inhibitors of PME-1: fluorescence-based dose response cell-based gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of ABHD10.
Protein phosphatase methylesterase-1 (PME-1)-mediated methylesterification is thought to control the binding of different subunits to protein phosphatase 2A (PP2A) (1), which, along with protein phosphatase 1 (PP1), is responsible for > 90% of all serine/threonine phosphatase activity (2). PME-1 has also been identified as a protector of sustained ERK pathway activity in malignant gliomas (3), suggesting a link between cancer progression and PME-1-regulated methylesterification. A fluorescence-polarization activity-based protein profiling (fluopol-ABPP) HTS assay for PME-1 inhibitor discovery (AIDs 2130 and 2171) unveiled a phenomenal class of potent and selective inhibitors, the aza-beta lactams (ABLs). During medicinal chemistry campaign to refine ABL inhibitors for PME-1 (See Probe Report for ML174 on the NCBI bookshelf http://www.ncbi.nlm.nih.gov/books/NBK47352/), we observed that one of the common anti-targets of several ABL members was the uncharacterized serine hydrolase abhydrolase domain containing protein 10 (ABHD10). We have preliminary evidence that ABHD10 functions as a lipase in situ (unpublished); however is physiological substrates and biological role(s) have not yet been explored. A principle goal of post-genomic research is to elucidate the molecular and cellular roles of uncharacterized enzymes like ABHD10, work that requires selective chemical tools to inactivate enzyme activity in a controlled manner.
1. Wu, J., Tolstykh, T., Lee, J., Boyd, K., Stock, J. B., Broach, J. R. (2000). Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo. Embo J. 19, 5672-5681.
2. Oliver, C. J., Shenolikar, S. (1998). Physiologic importance of protein phosphatase inhibitors. Front. Biosci. 3, D961-972.
3. Puustinen, P., Junttila, M. R., Vanhatupa, S., Sablina, A. A., Hector, M. E., Teittinen, K., Raheem, O., Ketola, K., Lin, S., Kast, J., Haapasalo, H., Hahn, W. C., Westermarck, J. (2009). PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma. Cancer Res. 69, 2870-2877.
late stage, late stage AID, assay provider, powders, dose response, abhdyrolase domain containing protein 10, ABHD10, uncharacterized, PME-1, protein phosphatase methylesterase 1, PPME-1, counterscreen, activity-based protein profiling, ABPP, inhibition, IC50, dose response, in situ, Neuro-2A, neuroblastoma cells, fluorophosphonate rhodamine, FP-Rh, inhibitor, selectivity, anti-targets, Scripps, Scripps Research Institute Molecular Screening Center, SRIMSC, Molecular Libraries Probe Production Centers Network, MLPCN
Assay Overview:
The purpose of this assay is to determine the IC50 values of powder samples of test compounds for ABHD10 inhibition in situ. In this assay, cultured cells are incubated with test compound. Cells are harvested, homogenized, and reacted with a rhodamine-conjugated fluorophosphonate (FP-Rh) activity-based probe. The reaction products are separated by SDS-PAGE and visualized in-gel using a flatbed fluorescence scanner. The percentage activity remaining is determined by measuring the integrated optical density of the bands. As designed, test compounds that act as ABHD10 inhibitors will prevent enzyme-probe interactions, thereby decreasing the proportion of bound fluorescent probe, giving lower fluorescence intensity in the band in the gel.
Protocol Summary:
Cultured Neuro-2A murine neuroblastoma cells in serum-free DMEM medium (1 mL total volume) were treated with DMSO or test compound (10 uL of a 100x stock in DMSO) for 2 hours at 37 C. Cells were washed with DPBS, harvested, and resuspended in DPBS (1 mL). Centrifugation (1000 x g, 5 minutes) provided a cell pellet which was resuspended in DPBS (200 uL) and homogenized by sonication. The protein concentration was adjusted to 1 mg/mL with DPBS. FP-Rh (1 uL of 50x stock in DMSO) was added to a final concentration of 1 uM in 50 uL total reaction volume. The reaction was incubated for 30 minutes at 25 C, quenched with 4x SDS-PAGE loading buffer, separated by SDS-PAGE and visualized by in-gel fluorescent scanning. The percentage activity remaining was determined by measuring the integrated optical density of the ABHD10 band relative to a DMSO-only (no compound) control. IC50 values for inhibition of ABHD10 were determined from dose-response curves from three replicates at each inhibitor concentration (10 uM, 1 uM, 0.250 uM, 0.050 uM, 0.010 uM, 0.005 uM, and 0.001 uM).
The % inhibition was then calculated as follows:
%_Inhibition = ( 1 - ( IOD_Test_Compound - Median_IOD_Low_Control ) / ( Median_IOD_High_Control - Median_IOD_Low_Control ) ) * 100
Test_Compound is defined as ABHD10 treated with test compound.
High_Control is defined as ABHD10 treated with DMSO only (no compound).
Low_Control is defined as background in a blank region of the gel.
For each test compound, percent inhibition was plotted against the log of the compound concentration. A four parameter variable slope equation describing a sigmoidal dose-response curve was then fitted using GraphPad Prism (GraphPad Software Inc). The software-generated IC50 values are reported.
PubChem Activity Outcome:
Compounds with IC50 less than or equal to 0.5 uM were considered active. Compounds with IC50 greater than 0.5 uM were considered inactive.
The reported PubChem Activity Score has been normalized to 100% observed inhibition. Negative % inhibition values are reported as activity score zero.
The PubChem Activity Score range for active compounds is 100-100. There are no inactive compounds.
List of Reagents:
Neuro-2A murine cells (provided by Assay Provider)
FP-Rh (provided by the Assay Provider)
DMEM Medium (CellGro 10-017-CV)
DPBS (Cellgro 20-031-CV)
This assay was performed by the assay provider with powder samples of synthetic compounds.
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
BAO: assay format: biochemical format: protein format: protein complex format
BAO: bioassay specification: assay biosafety level: bsl1
BAO: bioassay specification: assay measurement type: endpoint assay
BAO: bioassay specification: assay readout content: assay readout method: regular screening
BAO: bioassay specification: assay readout content: content readout type: single readout
BAO: bioassay specification: assay stage: secondary: alternate confirmatory
BAO: detection technology: fluorescence: fluorescence intensity
BAO: meta target detail: binding reporter specification: interaction: protein-small molecule
BAO: meta target: molecular target: protein target: enzyme: generic hydrolase
BAO: version: 1.4b1090
From PubChem:
Assay Format: Cell-based
Assay Cell Type: Neuro-2A
From ChEMBL:
Assay Format: Cell-based
Assay Type: Functional
Result Definitions
* Activity Concentration. ** Test Concentration.
Additional Information
Grant Number: 1 R01 CA132630
Data Table (Concise)


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