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Hi new to the forum. I was wondering on idea's and help with building my press for my shop. I mainly need it for removing bearings and installing bearings. And probably a few other things. Any help would be appreciate Thanx
Results 1 to 9 of 9
Thread: press
01-08-2012, 02:19 PM #1Junior Member
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Here is mine. I have since went with a 12t jack instead of the 6t shown...BobBob Wright, Grandson of Tee Nee Boat Trailer Founder
Metal Master Fab Salem, Oh 44460
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hi, you may want to look at the harbor freight 20 ton press. It maybe cheaper than building it. Like its said here, "why buy it for $200 when you can build it for $300'' ! Here is the press. Make sure to use a 20% off coupon too. You should buy it for $159 which has been the going price. just a thought.
01-08-2012, 09:37 PM #4Senior Member
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- Feb 2004
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- 1,225
Because if you build it you can actually have decent welds on your press. And you can put an American made ram on it. If that kind of thing matters to you.
If not, just buy the cheapest chinese junk you can find, fund the chinese military, employ slave/convict labor and enjoy your press, I guess.
JT, Made in the USASome days you eat the bear. And some days the bear eats you.
01-08-2012, 10:42 PM #5Senior Member
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- Jun 2009
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- greenfield new hampshire
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- 895
real nice job bob, i make most of my fixtures like that also, but i did buy a cheapy press, at the time i was burnt out with building things, i needed a press so i bought one for setting up ring and pinions, one thing i know, if it is home built, and done right, it will be far superior than any import
01-09-2012, 11:13 AM #6Member
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- Jan 2012
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- goldsboro north carolina
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- 42
i bought the 20t harbor freight press as well. got it for just over 100 on sale. i will build my own cradel for it sometime soon to have a wider mouth for more versitility.
if you want to build one by all means do it.. if your only pressing bearings and stuff like that go on craigslist and find a used one. time= money i can spend $300 in materials and a day or two of labor building one or i can buy one in the morning and make $400 in the 2 days of time doing other jobs. just my opinion. i agree with buying things that are american made but there is a point where practicalliaty comes in to play. i buy american vehicles and run them on e85 when i can find it...if i bought everything that was american made i couldnt afford to eat.
01-09-2012, 12:44 PM #7Junior Member
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01-13-2012, 08:32 PM #8Junior Member
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Swagoffroad.com has a DIY Kit that also comes with bender for $149
01-14-2012, 11:23 AM #9Junior Member
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- Apr 2011
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Wait till you put a little too much pressure on that Chinese piece of junk and it folds up on you!


text: hey Gonz, saaaay you are in the lounge and an emergancy happens in the Dolphin forum, is there like a special signal we can give you to bring your service. Could we get a "panic" button maybe...shaped like a babe? When the emergancy occurs it will be to late to ask questions, action will be needed, we need a button now.

subset: commoncrawl


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Stedman Bailey would fit in our offense perfectly.
Stedman Bailey would fit in our offense perfectly.
I have no idea who we should draft, I have never watched a college game in my life. But I hope we use our first round and our highest second round pick on wide receivers. Then id like to see us try and replace Vonte Davis in the second round as well. After that I dont know, just fill what ever holes need filled, right guard perhaps.
Hopefully next years draft will bring improvement and the one after that could actually make us competitive.
Also a hypothetical question for you draft nerds, if Tannehill had stayed another year in Texas, played well and showed solid progression what pick would he have been in 2013?
Tannehill couldn't stay another year because he was already a Senior. Secondly, he was better as a junior than he was as a senior.
One thing I notice watching most of these receivers is a tendancy for dropped passes. For some of 'em it isn't necessarily something new... but for some of 'em it is.
I see them all, including several that are probably a little off the radar of the general draft community and underrated prospects. The only one's I haven't seen any dropped passes from are Stedman Bailey and Aaron Dobson.
One of the most underrated defensive ends I've found is Western Kentucky's Quanterus Smith. This kid could start in the SEC.
He's 6'5", 250 pounds with incredible quickness... and he can bend. I watched him personally wreck Alabama's offensive line last Saturday for 3 sacks and 3 TFL's. I dug in to some of his 2011 film and watched him dominate Sun Belt competition week in and week out. Very talented and well coached kid that will likely find his way higher on my board than most.
Coach Taggert's squad has another very underrated linebacker that I already knew about. He's an underclassman and unlikely to come out this year although it's certainly possible by the name of Andrew Jackson. At 6'1", 255 pounds he moves, plays, and reacts a lot like a young Ray Lewis. In fact, he played at the same high school as Ray Lewis (Kathleen). Jackson had offers on the table from SEC schools.
It's no coincidence that this team plays everybody tough, and beat Kentucky yesterday. Despite some of the underrated talent they have, they're just so well coached....especially in the front 7.
Joe Fauria is a nightmare mismatch in the redzone. UCLA likes to use him in the slot or lined up at the "X" position to run some X-iso and get a mismatch on a cornerback. However, he has no clue when it comes to blocking out of a 3-point stance, and that's being generous. Tremendous weapon in the passing game.
Datone Jones is an absolute animal at DE for UCLA. Even got some time on offense and caught a touchdown pass Saturday vs. Houston.
Shamarko Thomas is a kid that I've talked about since May as an underrated safety prospect. Ironically, he finally got his first career interception in man coverage against what is probably the most dynamic passing combination in the country... a Matt Barkley pass intended for Robert Woods down the seam vs. USC. Just an outstanding play by Thomas.
Neither Knile Davis, Marcus Lattimore, or Justin Hunter look 100% healthy at this point. I know what they look like completely healthy and they're just not there yet.... nor are they supposed to be this soon.


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Tony D said about: Swift Transport Training
I booked my cat.c lessons with swift I found the lessons excellent. Alan was a very experienced instructor and made me feel at ease straight away he taught me everything I needed to know to pass first time and be safe on the road....
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It's simple! And simply terrific! Your spectator cuts a deck of cards. The card that is on top of the cut pile is set aside. You place a half dollar into the spectator's hand, and ask him to wave his hand over the chosen card. The card is turned over- it's the 7 of Hearts. And when he opens his hand- the half dollar has a "7" and a "heart" punched out of it!
Yes- the half dollar is a REAL U.S. half dollar coin!
And yes, you have to force the 7 of Hearts card. We show you exactly how to force the card in the FREE VIDEO below. And if you'd like to learn other easy methods of forcing a card, please see the Forcing a Card DVD.
You also have to switch the real half dollar for the punched one. Just watch how Peter Monticup does it in the video demo above.
punched out US half dollar coinprinted instructionsYou supply your own deck of ordinary playing cards.You also supply a real ordinary US half dollar coin.
Is it illegal to use real US coins to make magic tricks? According to the U.S. Treasury F.A.Q., the answer is- No. It is only illegal to alter a US coin with the intention of spending it as if it were a coin of a different value.From the official U.S. Treasury website: "Section 331 of Title 18 of the United States code provides criminal penalties for anyone who 'fraudulently alters, defaces, mutilates impairs, diminishes, falsifies, scales, or lightens any of the coins coined at the Mints of the United States.' This statute means that you may be violating the law if you change the appearance of the coin and fraudulently represent it [in a monetary transaction in trade for goods or services] to be other than the altered coin that it is. As a matter of policy, the U.S. Mint does not promote coloring, plating or altering U.S. coinage: however, there are no sanctions against such activity absent fraudulent intent."


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Fall 2010: Get Together & Get to Work
By PAN's analysis, the key strategic task of this moment is to gather strength and momentum—build power—to engage in the public struggle for America's values with truth and compelling stories, and redouble our efforts where mega-corporations have the least influence: local organizing and movement building. In this issue we call for reclaiming our democratic roots and gathering our friends to build power for change from the ground up. We unmask mythmakers who work to keep us off balance, and we report on progress toward breaking the bonds of the corporate food system.


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"They can think whatever they want. But as far as, by the law, I'm right….
Shouted out after victory to the UFC masses, BJPENN.COM is the home to multiple time champion BJ Penn. After a decade of on-line operation BJPENN.COM has evolved into the most reliable destination for all your fighter interviews, fighter blogs and MMA/UFC news stories.
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I was just wondering what the most up-to-date source for US Zip Code boundaries would be. My first thought was TIGER, whenever that comes out, but then I thought that the Postal Service might be a better bet. Does anyone have some input?
One thing to keep in mind is the fact that Zip Codes are not polygons, and therefore do not have boundaries. Zip Codes are lines (delivery routes) or points (Post Offices). See the Census Bureau website for a brief explanation. Also, the paper Zip Codes are Not Polygons
gives a good overview of the situation.
All that being said, when I need to use Zip Codes, first place I look is at the ESRI data that used to come on CDs with ArcView/GIS, but is now available online at: Esri Data & Maps
Maponics provides ZIP Code Boundaries and updates them each quarter with data directly from the USPS (and in fact, we are the only ZIP Code data provider that the USPS refers its customer to). While it is true that the data from the USPS is not in the form of geographic boundaries, we use numerous methods and algorithms to create boundaries from carrier routes and other data. The results are the most current available and can be purchased or licensed (with quarterly updates included) in a variety of GIS formats.
A five-digit ZIP code covers an arbitrary collection of delivery points (addresses). The USPS is the sole determiner of what ZIP code is assigned to what address, so they are the best source of current and correct data, which changes monthly. Cheap sources of current data are vendors like Semaphore Corporation.
Addresses within a ZIP code are assigned to numbered delivery routes. Addresses along the route are visited in a specific order, however there is no guarantee what path is taken by the mail carrier between two points along the route, so attempts at plotting routes as lines (or plotting all routes in a ZIP as a collection of lines) can't always be accurate.
Because ZIP codes are collections of points, the concept of "boundary" is ambiguous. It might mean computing the minimum rectangular bounding box enclosing all the addresses in a ZIP, or using a Graham scan to compute a "tighter" polygon, or using Lloyd's algorithm to polygonize a map, but how to choose the "best" boundary isn't always clear as shown in these 3 different boundaries for 5 points.
Since all addresses for a ZIP will be served by a single post office, it's tempting to start with that office's city boundary as the encompassing border for all ZIP codes served by that office, but exceptions occur: for example, a post office will serve ZIP codes outside the city, such as in unincorporated towns. Small towns often don't have street delivery; everything for a ZIP code might go to post office boxes at one location. And just over 100 "unique" ZIP codes are reserved for schools and businesses at a single location.
As Don points out, the US Postal Service makes available their detailed delivery routes with zip code, carrier route and zip+4 detail for every truck route. The USPS web site lists this data as their Zip+4 Product and it is available for yearly license. Conversion of this address-by-address detail into ZIP code (and Carrier Route) polygons is a somewhat sophisticated GIS problem, but with accurate geocoding, the polygon boundary definitions become visually obvious and algorithmically derivable. Other GIS competitors, like US DataMart also provide the current USPS ZIP code polygons for free viewing or for paid download at much more reasonable rates.
The USPS EDDM (Every Door Direct Mail) application displays our most recent ZIP code boundaries.
Few sites give neighborhood zip codes like this site. Most just give the standard Census City and Communities.
US Zipcode Boundaries API: https://www.mashape.com/vanitysoft/boundaries-io
Above API shows US Boundaries(GeoJson) by zipcode,city, and state. you should use the API programatically to handle large results.
for example:


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|Men's Golf » News » Schedule » Roster » Coaches » Statistics
Preview | RecapMeronk leads Bucs after first two rounds of General Hackler
Related Links
Monday, March 11, 2013
MURRELLS INLET, S.C. (March 11, 2013) – It was an up and down day for Adrian Meronk (Wroclaw, Poland), but the Buccaneer freshman still led the ETSU men's golf team after the first two rounds of the General Hackler Championship on Monday from the TPC Myrtle Beach.
Meronk – who opened the day with a 2-under-par 70 – followed things up with a 7-over 79 in the second round, and went from being tied for second into a three-way tie for 13th with a two-round total of 5-over 149. After registering six birdies in the first round, Meronk only totaled one in round two and finished the last two holes at 5-over.
Meanwhile, No. 17 Arkansas holds the lead on both the team and individual leaderboards.
In team scoring, the Razorbacks carry a two-shot lead over No. 23 Kent State into the final round. The Razorbacks finished the day at 6-over-par 582. Like his team, Thomas Sorensen holds a two-shot advantage over Tennessee's Oliver Goss, as the Arkansas golfer shot a 3-under 141.
As a team, the Bucs enter Tuesday's final round in fifth after carding a two-round total of 607 (299-308) on Monday.
The other ETSU notables were sophomore Rhys Pugh (Pontypridd, Wales) and freshman Chris Hickman (Centreville, Md.). The Buccaneer duo sit in a six-way tie for 20th after generating a score of 7-over 151.
The third and final round gets underway at 7:40 on Tuesday morning. ETSU will be paired with No. 47 Coastal Carolina and Lamar.
ETSU fans wanting to receive Buccaneer news, score updates, in-game promotions and much more sent to their mobile device can do so by signing up for "Buc Updates." Click here to sign up today!
For more information on Buccaneer men's golf, visit ETSUBucs.com and click on the men's golf page.
Men's Golf Archives
2012-13 Men's Golf


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Brine Lacrosse
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FORT WAYNE — When Kyree Ellis piped up from the backseat with, "I'm hit," after a single gunshot rang out, his cousins thought he was joking.
He wasn't, though, and unbeknownst to them, he was dying from a single .40-caliber gunshot wound to the back.
According to prosecutors, A.C. James Jr. murdered Ellis, 21, late on Feb. 3, 2012, after an argument with one of Ellis' cousins over a cellphone.
James, 38, of the 1700 block of Illinois Street, was originally charged with aggravated battery and criminal recklessness. Late last week, prosecutors added the charge of murder, just days before his trial in Allen Superior Court began Tuesday.
Allen County Deputy Prosecutor Jeff Stineburg told the jury during opening statements that, along with witness testimony, they will hear from a man who loaned James the truck that was spotted at the scene of the shooting. Inside the truck, police found a spent .40-caliber shell casing, which matched the brand on an empty box of ammunition that was found inside James' home, Stineburg said.
Testimony most of the day came from Ellis' cousins – Andrew Witt and Michael Lewis – who were in the car with him that night.
According to testimony and court documents, Lewis found a cellphone earlier that evening inside a gas station at East Paulding Road and Hanna Street. He took it over to Kyree Ellis' grandmother's house, where Ellis was hanging out with Witt, Luevenia Ellis, and other family and friends.
While Lewis was there, the cellphone rang repeatedly – with the person on the other end of the call trying to negotiate for the return of the phone. Lewis agreed to meet the phone's owner back at the gas station but wanted a finder's fee for returning the phone, according to testimony.
Lewis drove to the gas station in a small Kia SUV belonging to Luevenia Ellis, with Witt in the passenger seat and Kyree Ellis in the back.
At the gas station, a man later identified by Lewis as James approached the car, argued with Lewis about the phone and then walked away.
Witt testified he felt strange about the situation and suggested they leave the lot. Lewis pulled out, with a two-tone older pickup truck following close behind.
Lewis testified he tried unsuccessfully to lose the pickup truck on Paulding Road, running the traffic light at Lafayette Street. As he approached the intersection, a shot rang out and the pickup truck took off down parallel Avondale Drive.
Witt testified he noticed the rear window of the car was shot out, and then Ellis said he had been shot.
"He wasn't acting right," Witt testified.
Lewis drove back to the family member's home, and then Luevenia Ellis got in the car and drove Kyree Ellis to St. Joseph Hospital, where he died.
Luevenia Ellis testified that while she was driving to the hospital, a truck began following her and she heard another gunshot.
Lewis testified in a bright-orange Allen County Jail jumpsuit. He is awaiting sentencing after pleading guilty last month to voluntary manslaughter, having admitted to shooting 27-year-old Christopher Mhoon inside a Fort Wayne liquor store in June.
During opening statements Tuesday, James' defense attorney, Randy Fisher, argued that the evidence would not prove James was the gunman. During cross-examination, Fisher questioned witnesses about whether they saw James driving the truck that night.
The trial is expected to continue through Thursday.


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Everyone has to play by the rules. Here are the ones specific to watching Pirates games at PNC Park.
PNC Park has a natural grass field.
The outfield fence height varies from a mere six feet in left, to 10 feet by the left-center bullpens, to 21-feet in right in honor of Roberto Clemente.
PNC Park also features a 410-foot nook in the alley in deep left-center field.


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The Simpsons Movie: Not So Much "D'Oh" Just "Eh"
Do you remember that episode of The Simpsons where Homer won't let Bart go see the Itchy & Scratchy movie? And in the end it's like the year 2032 and Bart is a member of the Supreme Court and he finally goes to see the movie with Homer? I felt a little bit like that when The Simpsons Movie started. I was thinking about how long I've waited to see this movie and now I'm old and


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Hey gorgeous bar slaves and cocktailistas! This night's for you (and your friends). The annual Mid-Winter Barworkers Ball raises a glass to all service industry workers 9pm-2am Tue/18 at Churchill. Don't worry, it's free to barwokers, there's free drinks, great music -- and games, of which I am a judge, bwahahaha. Here's the rundown from the release:
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As part of the Wellness Center, the Disability Services staff promotes diversity and inclusion at UMass Lowell by partnering with the campus community. We create equal access by removing barriers, promoting diversity, employing universal design and striving for inclusion.
Finding Their Way
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The Literature For Children Collection
Literature for Children is a collection of the treasures of children's literature published largely in the United States and Great Britain from before 1850 to beyond 1950. At the core of this Collection are books from the Baldwin Library of Historical Children's Literature, housed in the Department of Special Collections and Area Studies at the University of Florida. Books from the Departments of Special Collections at the Florida Atlantic University, Florida State University, and the University of South Florida join volumes from the Baldwin Library to complete the Collection. The foundation for this Collection was a cataloging and preservation microfilming project funded by the National Endowment for the Humanities (NEH). The NEH project included a digital color management strategy for the reproduction of illustrations as children saw them.


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Practice Philosophy
Dr. Newman and his dedicated staff strive to provide the highest level of professional expertise and personal attention. After completing a comprehensive examination and listening to his patient's desires, Dr. Newman creates an individualized treatment plan. This tailored approach, combined with open communication leads to more rewarding results. At his state-of-the-art facility in Murrieta, California, Dr. David Newman offers a variety of plastic and cosmetic treatments. He performs aesthetic procedures for the face, breast and body including facelift, rhinoplasty, eyelid surgery, breast augmentation, lift and reduction and tummy tuck/liposuction procedures.
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Dr. Newman performs cosmetic and plastic surgery at The Breast and Cosmetic Surgery Center in Murrieta, CA. The Center is accredited by AAAHC, an independent agency approved by The Medical Board of California. Only board certified anesthesiologists have privileges at The Center and the anesthesiologists at The Cener have full privileges at Rancho Springs Medical Center.
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Home > Furniture > Entryway Furniture > Entryway Benches > Simpli Home Warm Shaker Collection Entryway Bench
Simpli Home Warm Shaker Collection Entryway Bench
Add function to your home with this elegant and stylish entryway bench.
The Warm Shaker Collection combines the warmth of a country home with the elegance of casual contemporary style. The style is defined by its shaker style drawers, door fronts, rounded rectangular brushed nickel knobs and tapered legs. Add this stunning functional furniture piece to your entryway, or any other room in the home with the Warm Shaker Entryway Bench. This sturdy and stylish bench offers convenient seating for putting on shoes that can be stored and hidden away right inside the bench itself with 2 big storage compartments.
- Solid plantation grown pine construction
- Attractive stain with protective lacquer finish
- 3 shaker doors open up to 2 storage spaces with 2 adjustable shelves
- Rounded rectangular brushed nickel knobs
Simpli Home Warm Shaker Collection Entryway Bench
Simpli Home Warm Shaker Collection Entryway Bench
Our innovative products will provide you and your family with years of enjoyment. And with the Brookstone Protection Plus service and replacement plans, you'll have the added peace of mind knowing that if the unexpected does happen, we will simply repair or replace your covered product. Our enhanced coverage goes above and beyond the manufacturer's warranty, saving you time and money.
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Cruise ships usually offer shore excursions that can be booked for an additional fee. These can be more expensive than going with a 3rd party, since the cruise line takes a cut. Is there a list of companies offering shore excursions in the Western Caribbean? Anyone have experience with a tour operator in particular in this region?
Take the 2-minute tour ×
Travel Stack Exchange is a question and answer site for road warriors and seasoned travelers. It's 100% free, no registration required.
Hah! I'm getting to re-use cruising tips I wrote almost ten years ago. Yay for recycled material!
Shore Excursions
There are generally two reasons to book your trips through the cruise line:
There's one other reason to go with cruise line tours: one of the nicest parts of cruising is the instant community that arises, and it's fun hanging out with some of the same people off the ship, too.
Yeah, the excursions are expensive. But hey, how often do you get a chance to take a helicopter to a glacier and then walk around? I did it on my first trip to Alaska, and while I feel no urge to do it again, it was a great experience and one that I'm happy I did.


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25 Oct 2007
|Printable version | Email to a friend
|World's Largest Halloween Jack-o-lantern Pumpkin Carving Display
This Saturday, October 27, Bennington VT is determined to win the Guinness World Record for the most jack-o-lanterns on display in one place. The current record is held by nearby Keene NH which set the record in 2003 with 28,952 officially counted.
Who says Americans don't have enough leisure time?
There will also be a Main Street parade at 4:00.
Seeing that many jack-o-lanterns will probably be an impressive sight so don't forget your camera.
Bennington is a nice town to visit with many architecturally and historically significant buildings. I recommend you take the walking tour around the Old First Church and cemetery on the west side of town. There is a very good quality Welcome Center in an old brick blacksmith's shop at the Corner of Route 7 and Elm Street where you can pick up literature on things to see. For some reason, it is closed on Sundays - when most visitors would be coming into town.
The Bennington website has a listing of local attractions.
You will also be near Arlington and Manchester, both of which are scenic towns. Manchester is known for its outlet stores but even if you won't want to go shopping, you should drive through this very pretty village. Just take Route 7 north from Bennington. It's about 15 minutes to Arlington and another 15 to Manchester where you will see the Reluctant Panther and the Equinox, both world class ($$$$) lodging and dining facilities. Since we are now entering "low season", The Equinox is running some specials, one of which offers three nights of lodging for just $333 - a fraction of what the rooms cost during busy seasons.
There are many other good quality inns and motels in the Manchester area that are not as expensive.
Southwest Vermont is one of my favorite areas to visit but it's been a while since I was there so I think I'll take another look at lodging places down there and get a trip scheduled soon.
(c) 2007 Jeff Connor
Bennington Old First Church,
the oldest church in Vermont
|posted by grunhaus at 22:12


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Reading a book on the Nook or iPad Mini comes in handy when you're in the slow-moving PCH passenger seat, but nothing compares to holding the good 'n honest spinal version. Truth be told, bookish weekends are a major incentive for reaching that Friday EOD finish line — we've even been known to forgo a night on the town just to stay in and revisit our favorite hard copies. But, to make up for the fact that we're eschewing heels for slippers, we get cozy with a high-fashion tome or two, clocking face time with the men who matter most: Tom Ford, Helmut Newton, and Mario Testino.
To that end, here are 30 coffee-table beauties we'd ditch our Friday and Saturday night plans for — without an ounce of guilt. Can you blame us? Perusing some of the most iconic garments in fashion history totally beats bellying up to an overhyped bar. Plus, we'd rather save our moolah to add another tome to our growing collection!


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Saturday afternoon in Columbia, with the hated Bulldogs of Georgia in town, and a mass of Gamecocks fanatics turning Williams Brice Stadium into a sea of red...there's no better place to be! This breathtaking panoramic poster celebrates SEC football at its finest. From a unique wide-angle perspective in the upper deck, the whole scene unfolds before your eyes, and as Marcus Lattimore crosses the goal line for his second TD of the game to send the home fans into a frenzy - SNAP! The moment is preserved for all-time, and is now available for your wall. From the action on the field, to the sideline entourages, to the cheerleaders, the scoreboards, the packed grandstands and jammed standing-room-only locations, this is the ultimate celebration of football on the USC campus! Whether you're a student, alumni, or simply a college football fan looking to capture the spirit and look of those beloved fall Saturday afternoons, this if for you - worthy of a nice frame and a central location on your sports wall-of-fame!
Product Specifications:


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Welcome to the biggest game in Chicago in a generation!
After a brilliant regular season, and a thrilling OT win over the Seattle
Seahawks the previous week, the Bears hosted the New Orleans Saintsfor
the NFC title and a chance at glory in Super Bowl XLI. With the excitement
level in The Windy City reaching levels not felt in 20 years, it was game-on,
and a packed house settled in for a great party atmosphere. As Rex Grossman
looks for another first down after leading his team to an early 6-0 lead...SNAP!
The moment is preserved for all-time, and is now available for your wall.
With this poster, you are transported back that dynamic
winter afternoon, when the entire city was abuzz with hopes for a second
Super Bowl championship. Like all prints in photographer Rob Arra's Everlasting
Images series, every detail is in perfect focus, and as you pan across
the image you feel like you are actually there! You can see the action
on the field, the players and coaches on the sidelines, the spectators
in the stands, the unique architecture, the giant video boards, the scoreboards,
and the darkening late-afternoon winter sky. A fantastic piece for the
wall of any football fan, and a great collector's item for years to come!
Whether you were watching on TV, or were there in person that day, this
is an absolute must for your Bears Wall-of-Fame.
Product Specifications:


text: Front Back Cone With optional grille Photos (4) Video View larger Polk Audio MM1040D Mobile Monitor Series 10" sub with dual 4-ohm voice coils Item #: 107MM1040D 15 Reviews This item is no longer available. Original Price: $169.99 Shop all Component Subwoofers Need help? 1.888.955.6000 Email Chat Ask an expert advisor No pressure, no commission — just lots of good advice from our highly trained staff. Overview Reviews Details Accessories Articles & Videos by Gabrielle Thorndyke Polk Audio's Mobile Monitor Series subwoofers bring out superior performance from lighter materials, so you'll get the impact you want without the extra weight of conventional construction. Advanced engineering and optimized components reproduce your sound with uncompromising accuracy, for low end that is rich and clear. The MM1040D 10" dual voice coil subwoofer handles up to 350 watts RMS. A copper voice coil and neodymium magnet motor drives the polymer cone with exceptional efficiency. The carbon composite basket features a "wagon wheel" design that resists flexing during heavy excursion, so your sub hits solidly without distorting. The dual 4-ohm voice coils offer options for wiring a multi-sub system or drawing maximum power from your mono amplifier. This sub is certified for marine use, and Polk includes corrosion-resistant stainless steel mounting hardware. Priced per speaker Product Highlights:10" subwoofer with dual 4-ohm voice coilspolymer cone with butyl rubber surroundcarbon composite basketcertified for marine useoptional matching grille complements the basket designpower range: 100-350 watts RMS (135 watts RMS per coil)peak power handling: 700 wattsfrequency response: 24-200 Hzsensitivity: 91 dBtop-mount depth: 4-9/16"sealed box volume: 0.66 cubic feetwarranty: 1 yearOur 60-day money-back guarantee What's a component sub and why would I want one? A component sub is simply a speaker that's designed to reproduce bass once it's installed in a compatible enclosure. Think about the impact of a movie soundtrack in a big theater or even in your own home HDTV setup. A component sub can add the same kind of power to the music in your car. And a car sub is not all about the boom that you hear on a street corner (although that's cool too) - you can pair a component sub with your choice of enclosure to get bass just the way you like it, from tight and punchy to fat and loose. And once you experience music in your car with a well-tuned subwoofer, you'll never go back. Polk Audio MM1040D Reviews Average Customer Review: 15 reviews Review this product Submit a review and then enter to win a $350 rewards card Filter by rating: 5 Star: (0) 4 Star: (0) 3 Star: (0) 2 Star: (0) 1 Star: (0) Review this product: Thanks for taking the time to share your experiences about this product. Please be sure to focus your comments on the product itself. Read our Review Guidelines for more information. Review title * Email Your email won't be visible. Please use the email address that is associated with your order. Display name (e.g., JohnD) Your review will be signed using the display name and location * Your location (e.g., Charlottesville, VA) * Your rating Click on a star to rate the overall product on a scale of 1-5 Rate the following specific attributes Value Sound Quality Ease of Use "Coolness Factor" Build Quality 1500 characters left * Your review Attach a YouTube Review Crutchfield Video Review Guidelines Only submit videos that you made or are authorized to use. Do not submit videos that contain music, video or visuals that are copyrighted and belong to someone else. Please see our Review Guidelines for more information. Enter the URL of your YouTube™ video review or product demonstration. e.g., "http://www.youtube.com/v/o79TWHh598U" 500 characters left Pros 500 characters left Cons * Agree to Terms By checking this box you agree your review becomes the property of Crutchfield, that you are over 18 years of age, that you own or have owned this product, and that you are located within the United States or its territories. Please see our Review Guidelines for more information. We reserve the right (but are not obligated to) review all submissions and edit or remove any review in any manner which we deem necessary. Your review should be posted within seven days. Great sub!!!!! Written By Spiro, Minnesota on Sunday, September 01, 2013 Crutchfield Customer Review (What's this?) "Coolness Factor" Build Quality Ease of Use Sound Quality Value Great sounding subs installed two of them on my boat, connected to 300.2 amp plenty of power. Connect to show 4 ohm load. Very pleased Pros: Great sounding bass, dvc kept the load at 4 ohms. So I could existing amp Cons: None Was this review helpful? Yes No The last mm1040d Written By FALLGUY, GIG HARBOR .WA. on Monday, August 12, 2013 Crutchfield Customer Review (What's this?) "Coolness Factor" Build Quality Ease of Use Sound Quality Value I AM STOKED!! I just bought the last MM1040 D Crutchfield had in stock, and possibly the last available! as they have been discontinued! I,m sure Polk w After reading all the EXCELLENT reviews,...i cant wait to incorporate it into my system! Was this review helpful? Yes No Powerful, tight, bass Written By DaveL., Los Angeles on Wednesday, July 24, 2013 Crutchfield Customer Review (What's this?) "Coolness Factor" Build Quality Ease of Use Sound Quality Value I bought one of these to replace some cheap aftermarket subs that were already installed in my recently purchased, used, ram 1500. The old subs were flabby, and... well, loose. Nothing I did made them sound "good". I took them both out and replaced them with a this single dual coil Polk. Instant improvement! The lows are now nice and tight with good definition, but it can still rattle windows when I want. Definitely a great buy! Pros: Quality, quality, quality. Sound quality, build quality, efficiency... I love it. Cons: My only point of contention was the mounting point of the speaker terminals. They are placed 180 degrees away from one another and opposite. I think most folks will want to go parallel for the extra power, but to make that work, I had to cross paths when connecting terminals. Not a big deal, but a little annoying. Was this review helpful? Yes No Great Written By Nikolay, Rancho Cucamonga CA on Thursday, July 18, 2013 "Coolness Factor" Build Quality Ease of Use Sound Quality Value Its a great sub doesn't have distortion and sound great. It great for all types of music. To some it may not be enough but i think with 2 in my truck it is just amazing! Pros: Well built Last for along time Was this review helpful? Yes No Much better for SQ than DB Written By MikeV, Fresno on Friday, March 08, 2013 "Coolness Factor" Build Quality Ease of Use Sound Quality Value By far the best SQ for rock, jazz, and the such. Dave Matthews sounds amazing. But it seems just a tad weak in the DEEP low bass. Now don't get me wrong it's not bad...but my older Memphis sub had that bowel shaking low bass. But it was not nearly as good as sound as this polk. And I'll trade consistent sq over occasional super low bass any day. Let the teenagers get the stupid bass. Pros: Sq Cons: Low low low db Was this review helpful? Yes No Polk Audio MM1040DVC Subwoofer Written By Zach, Montgomery, AL on Wednesday, November 28, 2012 "Coolness Factor" Build Quality Ease of Use Sound Quality Value I just got this product installed in my car, and Can't wait to try it out. I've seen a couple reviews about how this sub won't "knock the other car out of his lane with your bass." I wanted to recommend that if you want a sub that will hit harder and louder, look to Polk's sister company, Orion. They make excellent products as well, but I personally prefer Polk. Was this review helpful? Yes No Awesome sound quality...but a bit power hungry Written By Danno, Alabama on Tuesday, October 30, 2012 Crutchfield Customer Review (What's this?) "Coolness Factor" Build Quality Ease of Use Sound Quality Value I have mixed feelings on this sub. It may be one of the best sounding subs I've ever owned but this thing is power hungry. Maybe its my vehicle but it doesn't get as loud as some other subs I've owned. I'm pumping about a true 300 watts into this sub and I think it needs about twice that. I'm nit-picking of course since the sound quality of this sub is off the charts and its practically a shallow mount sub without being a shallow mount design. Maybe I was expecting too much from a single 10 in a big truck. I'm thinking of buying a 2nd one and upgrading the power to it since power is a lot cheaper than it used to be. Bottom line - As others have said, it sounds better than just about any sub I've ever heard in its price range. Pros: Looks Sound Quality Size Cons: A tad power hungry, but not bad at all. Was this review helpful? Yes No best sub for the money hands down! Written By B. rosser, northern wisconsin on Thursday, October 11, 2012 "Coolness Factor" Build Quality Ease of Use Sound Quality Value i bought this used off of a co-worker in july and have just now gotten around to getting my sound system started in my focus. its a 2003 svt 3 door hatchback, currently it has the factory audiophile front door speakers, and the stock one way 6x8's in the rear, those are powered off of my alpine deck. the bass on this thing is really exceptional if you build a large sealed box for it. a smaller box will make for tighter more sq styled bass but you'll lose low end punch, that said even my oversize box has great sq. it can get very loud in the car but standing outside you cannot tell i have much going on, which is what i like. i dont think i even need to do much soud deadening if any. planning of bolting two more into my box (its large enough for it) and seeing what i can get out of my 5 channel mtx amp. Pros: great sub, hit hard if you have the space to make a box big enough even in a space confined focus Cons: wish it was a bit cheaper new. so i could get two more. Was this review helpful? Yes No Pleasantly surprised Written By Jay, Laurel, MD on Sunday, July 08, 2012 Crutchfield Customer Review (What's this?) "Coolness Factor" Build Quality Ease of Use Sound Quality Value This is a shallow but heavy sub woofer, but you can feel the quality in the structure the moment it comes out of the box. I love the rubber surround (my former sub was foam and it was shreded). But most importantly this thing sounds great! My set up is as follows mm6501 6.5 component mm1040d subwoofer pad 4000 4x125 amp This set up is awesome provided you have a decent source. it hits hard with rap, is tight with jazz bass, and adds harmonics that even make NPR sound more full. All without being overbearing. With the mm6501 the base sounds like its coming from the front of the car and not thumping from the back. For the money I don't think you can beat the Cleanliness, Sound Pressure and Fidelity of this system. Its only going to get better as the woofer breaks in. Pros: Sounds great Flexible installation with the dual voice coils Cost Cons: Can't think of any 3 out of 3 people found this helpful Was this review helpful? Yes No much better then a w3 Written By mr 350z, florida on Saturday, May 12, 2012 "Coolness Factor" Build Quality Ease of Use Sound Quality Value owned L5's, and w3's, these sub kick the heck out of the w3's and have better sound quality then the L5. im very happy with my purchase 1 out of 1 people found this helpful Was this review helpful? Yes No Bang for the buck! Written By Wes, Delaware on Saturday, May 12, 2012 Crutchfield Customer Review (What's this?) "Coolness Factor" Build Quality Ease of Use Sound Quality Value Great sub for the money! Had a w1 and build quality on the Polk is far superior, dvc and cheaper!!! Pros: Loud, tight bass and very efficient sub Cons: Doesnt really dig as low as I'd like but it's also in a frontier so options were limited. Was this review helpful? Yes No Polk Audio MM1040D Written By RobertJ, Phoenix Az on Friday, September 16, 2011 I've had one these subs in my trunk for a little while now and I have been playing around with different box configurations. I tried Polk's recommendations at first, both sealed and ported, but I wasn't happy with the performance. So I decided to put the numbers in my BassBox Pro software and see what I could come up with. Wow, with the right enclosure this little sub sings.The sub is very musical and clear sounding with very deep lows. Whatever genre of music you are into this sub fills in the bottom end nicely. Trust me, I listen to just about everything from Bass Mekanic to Beethoven. The bass is tight and musical; not just boomy and loud. Now one of these will not knock your neighbors nick-naks off the shelf but they can hear you coming and that's fine with me. I like a sub that sounds musical and clear but I do love to rattle the windows once in awhile and this sub does the job very well. So in my opinion, If you want a good musical sub that sounds good no matter what you listen than this will do the trick. But if you want to knock the other car out of his lane with your bass then look somewhere else. 5 out of 6 people found this helpful Was this review helpful? Yes No Quality at the best price Written By aaron, chelan, wa on Wednesday, April 06, 2011 I have a single 10 right now in a sealed box with .8 cubic feet, with 300watts RMS from a phoenix gold 500zx (the old white ones). Pounds really good, and it isn't even broken in yet. Other people were commenting that it wasn't able to go low on rap and r&b songs were mistaken. Hits almost as loud as a type R, but way better sound quality. Getting another one here shortly, and im sure that will fill in the little extra i want out of em. Overall amazing sub, good job polk~ 1 out of 1 people found this helpful Was this review helpful? Yes No Decent Performer Written By Josh, Bay Area, CA on Tuesday, March 03, 2009 Due to reliability issues in the past I went away from mainstream sub companies and moved to internet sub companies and had great success. Due to clearance issues my choices were limited and being so impressed with Polk components I decided to try out a pair of these. So far the subs sound great with classical rock, light rock, classical music and some heavier rock. The subs are dissappointing when it comes to hip hop and rap as their lower end extension isn't the best. The subs sound great as I said but don't get very loud. This is fine for me as I'm getting passed my years of blasting rap and hip hop. I have a feeling the 12's probably produce much better low end bass and probably have greater output. I unfortunately had to pass on them due to clearance issues. If you have room get the 12's. 2 out of 6 people found this helpful Was this review helpful? Yes No Excellent Subwoofer Written By Cammie, Darlington SC on Saturday, November 22, 2008 Crutchfield Customer Review (What's this?) This is the best sounding shallow mount sub period. The sound quality of this sub is awesome. This sub hits clean deep and hard. I have had the kicker cvt shallow mount sub. The pioneer shallow mount sub and the rockford fosgate shallow mount sub. And this sub puts them all to shame. You won't be disappointed with this sub. 11 out of 14 people found this helpful Was this review helpful? Yes No Hands-on research Features and specs chart | What's in the box? | In-depth notes What's in the box? Download owner's manual 10" Dual 4-ohm voice coil subwoofer Foam gasket 8 Mounting screws 8 Speed-clips Owner's Manual Product Registration Information sheet Features and Specs Size 10 -inch Impedance 4 ohms Cone Material Polymer Surround Material Butyl Rubber Ideal Sealed Box Volume (cubic feet) 0.66 Ideal Ported Box Volume (cubic feet) 1 Port diameter (inches) N/A Port length (inches) N/A Free-Air No Dual Voice Coil Yes Sensitivity 91 dB at 1 watt Frequency Response 24 - 200 Hz RMS Power Range (Watts) 100-350 Peak Power Handling (Watts) 700 Top Mount Depth (inches) 4 9/16 Bottom Mount Depth (inches) 5 1/8 Cutout Diameter or Length (inches) 9 1/16 Vas (liters) 18 Fs (Hz) 35 Qts 0.5 Xmax (millimeters) 0 Parts Warranty 1 Year Labor Warranty 1 Year Product Research Features Enclosure Compatibility Features Klippel Optimized: Using a state-of-the-art Klippel Distortion Analyzer, Polk engineers were able to optimize the woofer's motor structure, voice coil alignment and suspension for the best possible performance, even at extreme listening levels. Polymer Woofer Cone with Butyl Rubber Surrounds: The Polymer Woofer Cones and Butyl Rubber Surrounds will not break down over time and will survive the rigors of harsh automotive environments. High Temperature Copper Voice Coil (50mm) and Polyamide Former: High Temperature 50mm Copper Voice Coil and Polyamide Former withstand the most rigorous use while maintaining extremely low distortion for bass punch and output. Dual 4-ohm Voice Coils: This woofer features dual 4-ohm voice coils that offer wiring flexibility. When the voice coils are wired in parallel, the woofer presents a 2-ohm load. When wired in series, the woofer presents an 8-ohm load. Carbon Composite Basket: The woofer's carbon composite basket is lightweight and will not flex during music audio peaks. Nickel Plated Heavy Duty Input Terminals: Nickel plated heavy duty input spring-post terminals accommodate speaker wire up to 8 AWG or twisted pairs of 12 AWG. Preconditioning Period: Mobile Monitor subwoofers will achieve even greater performance once they are thoroughly broken in. To break in your new MM subwoofer, play 20 to 30 hours of music at moderate levels. Marine Certified Woofer: Polk MM Series woofers are built to withstand exposure to moisture and UV rays, so they work well in boats and cars. They also include stainless mounting hardware for corrosion and rust resistance. Enclosure Compatibility Recommended Sealed Box Volume: Polk recommends mounting this woofer in a sealed enclosure made out of 3/4" MDF with an internal volume of 0.66 cubic feet. Recommended Ported Box Volume: Polk recommends a ported enclosure made out of 3/4" MDF with an ideal internal volume of 1.0 cubic feet using a slot port measuring 13.5" wide x 1" tall x 20" deep. Our Product Research Team At Crutchfield, you'll get detailed, accurate information that's hard to find elsewhere. That's because we have our own in-house Product Research team. They verify what's in the box, check the owner's manual, and record dimensions, features and specs. We stay on top of new products and technologies to help people make informed choices. Sorry, the Polk Audio MM1040D is no longer available. Looking for a similar item? Shop all Component Subwoofers Or, you can still... Write a review Purchase accessories for this product Download the product manual Search the website Go


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Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR8
Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David Weaver ..more
BioActive Compound: 1
Related Experiments
Assigned Assay Grant Number: NS053536-01
Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David Weaver
Chemistry Center Name & PI: Vanderbilt Specialized Chemistry Center for Accelerated Probe Development, Craig W. Lindsley
Assay Submitter & Institution: Colleen M. Niswender, Vanderbilt University
The primary pathophysiological change giving rise to the symptoms of Parkinson's disease (PD) is a loss of the dopaminergic neurons in the substantia nigra pars compacta (SNc) that are involved in modulating the function of basal ganglia (BG) nuclei. Unfortunately, traditional therapies for treatment of PD based on dopamine replacement strategies eventually fail in most patients and are associated with numerous side effects. A great deal of effort has been focused on developing a detailed understanding of the circuitry and function of the BG to develop novel, nondopaminergic, approaches for restoring normal BG function in PD patients. Exciting advances suggest that metabotropic glutamate receptors (mGluRs), including the group III mGluRs (mGluR4, -7 and -8), play important roles in regulating transmission through the BG and could serve as targets for novel PD therapeutics (Conn et al., 2005). For instance, mGluR4 activation reduces overactive GABA release at a specific inhibitory BG synapse (Macinnes and Duty, 2008; Marino et al., 2003; Valenti et al., 2003) and reverses motor deficits in a variety of rodent PD models (Konieczny et al., 2007; MacInnes et al., 2004; Marino et al., 2003; Ossowska et al., 2007; Valenti et al., 2003).
To more selectively activate mGluR4 and improve upon the pharmacokinetic liabilities of glutamate analogs, we and others have developed novel positive allosteric modulators (PAMs) which potentiate glutamate function at mGluR4 (Engers et al., 2009; Maj et al., 2003; Marino et al., 2003; Niswender et al., 2008a; Niswender et al., 2008b; Williams et al., 2008); several of these tool compounds exhibit antiparkinsonian and neuroprotective effects in multiple rodent PD models (Battaglia et al., 2006; Marino et al., 2003; Niswender et al., 2008a). Unfortunately, many available compounds have lacked pharmacokinetic properties to make them useful tools for study of mGluR4 function via systemic routes of administration. The probe compound developed here exhibits sufficient potency, efficacy, and pharmacokinetic properties, including brain penetration, to make it a useful compound to progress mGluR4 biology, which will undoubtedly allow the intense study of mGluR4 activation in multiple areas of neuroscience such as psychiatric disorders (Stachowicz et al., 2006; Stachowicz et al., 2004), cancer (Iacovelli et al., 2006), and addiction (Blednov et al., 2004).
1. Battaglia G, Busceti CL, Molinaro G, Biagioni F, Traficante A, Nicoletti F and Bruno V (2006) Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurosci 26(27):7222-7229.
2. Blednov YA, Walker D, Osterndorf-Kahanek E and Harris RA (2004) Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol. Alcohol 34(2-3):251-259.
3. Conn PJ, Battaglia G, Marino MJ and Nicoletti F (2005) Metabotropic glutamate receptors in the basal ganglia motor circuit. Nat Rev Neurosci 6(10):787-798.
4. Engers DW, Niswender CM, Weaver CD, Jadhav S, Menon UN, Zamorano R, Conn PJ, Lindsley CW and Hopkins CR (2009) Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs). J Med Chem 52(14):4115-4118.
5. Iacovelli L, Arcella A, Battaglia G, Pazzaglia S, Aronica E, Spinsanti P, Caruso A, De Smaele E, Saran A, Gulino A, D'Onofrio M, Giangaspero F and Nicoletti F (2006) Pharmacological activation of mGlu4 metabotropic glutamate receptors inhibits the growth of medulloblastomas. J Neurosci 26(32):8388-8397.
6. Konieczny J, Wardas J, Kuter K, Pilc A and Ossowska K (2007) The influence of group III metabotropic glutamate receptor stimulation by (1S,3R,4S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid on the parkinsonian-like akinesia and striatal proenkephalin and prodynorphin mRNA expression in rats. Neuroscience 145(2):611-620.
7. Macinnes N and Duty S (2008) Group III metabotropic glutamate receptors act as hetero-receptors modulating evoked GABA release in the globus pallidus in vivo. Eur J Pharmacol 580(1-2):95-99.
8. MacInnes N, Messenger MJ and Duty S (2004) Activation of group III metabotropic glutamate receptors in selected regions of the basal ganglia alleviates akinesia in the reserpine-treated rat. Br J Pharmacol 141(1):15-22.
9. Maj M, Bruno V, Dragic Z, Yamamoto R, Battaglia G, Inderbitzin W, Stoehr N, Stein T, Gasparini F, Vranesic I, Kuhn R, Nicoletti F and Flor PJ (2003) (-)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection. Neuropharmacology 45(7):895-906.
10. Marino MJ, Williams DL, Jr., O'Brien JA, Valenti O, McDonald TP, Clements MK, Wang R, DiLella AG, Hess JF, Kinney GG and Conn PJ (2003) Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment. Proc Natl Acad Sci U S A 100(23):13668-13673.
11. Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL, Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB, Ayala JE, Williams R, Lindsley CW and Conn PJ (2008a) Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol 74(5):1345-1358.
12. Niswender CM, Lebois EP, Luo Q, Kim K, Muchalski H, Yin H, Conn PJ and Lindsley CW (2008b) Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett 18(20):5626-5630.
13. Ossowska K, Konieczny J, Wardas J, Pietraszek M, Kuter K, Wolfarth S and Pilc A (2007) An influence of ligands of metabotropic glutamate receptor subtypes on parkinsonian-like symptoms and the striatopallidal pathway in rats. Amino Acids 32(2):179-188.
14. Stachowicz K, Chojnacka-Wojcik E, Klak K and Pilc A (2006) Anxiolytic-like effects of group III mGlu receptor ligands in the hippocampus involve GABAA signaling. Pharmacol Rep 58(6):820-826.
15. Stachowicz K, Klak K, Klodzinska A, Chojnacka-Wojcik E and Pilc A (2004) Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats. Eur J Pharmacol 498(1-3):153-156.
16. Valenti O, Marino MJ, Wittmann M, Lis E, DiLella AG, Kinney GG and Conn PJ (2003) Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse. J Neurosci 23(18):7218-7226.
17. Williams R, Niswender CM, Luo Q, Le U, Conn PJ and Lindsley CW (2008) Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-lead. Bioorg Med Chem Lett.
Basic protocol:
1. Cells are plated at a density of 20,000 cells/well 1 day prior to assay in Thallium Assay Media (DMEM + 20mM HEPES, 10% dialyzed FBS, 1mM sodium pyruvate).
2. The following day, media is removed from the cells.
3. 20 ul/well of Fluo Zn dye (0.33 uM) in Assay Buffer (HBSS + 20mM HEPES) is added.
4. The plates are incubated for one hour at RT.
5. Dye is removed from the cells and the cell are washed with Assay Buffer leaving 20uL residual volume.
6. Plates are incubated for 10 minutes at RT.
7. Plates are loaded into a Hamamatsu FDSS.
8. Compounds are tested for selectivity at a 10 uM final concentration (prepared as a 2X stock, 20 ul added per well) and the agonist (glutamate) is added at a 5X concentration (10 ul of agonist added per well, 50 uL total volume). A baseline read is taken for 1.5 seconds, the first addition (compound or DMSO-matched vehicle) occurs at 1.5 seconds and the second addition (agonist) is added at 142 seconds. The read continues for 300 seconds.
Data analysis:
Data were analyzed using Microsoft Excel. Raw data were opened in Excel and each data point in a given trace was divided by the first data point from that trace (static ratio). For experiments in which antagonists/potentiators were added, data were again normalized by dividing each point by the fluorescence value immediately before the agonist addition to correct for any subtle differences in the baseline traces after the compound incubation period. The slope of the fluorescence increase beginning five seconds after thallium/agonist addition and ending fifteen seconds after thallium/agonist addition was calculated. Curves were fitted using a four point logistical equation using Microsoft XLfit (IDBS, Bridgewater, NJ).
Compounds that gave a foldshift of <2.5 were assigned as 'Inactive' and a 'Score' of '0'. For compounds with foldshift >/= 2.5 were considered positive allosteric modulators of rat mGluR8 and were assigned an 'Outcome' of 'Active' and a 'Score' of '50'. For compounds with foldshift >/= 5.0 were assinged a 'Score' of '100'.
Categorized Comment - additional comments and annotations
From ChEMBL:
Assay Type: Functional
Result Definitions
* Activity Concentration. ** Test Concentration.
Additional Information
Grant Number: NS053536-01
Data Table (Concise)


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I'm really starting to like Hyperdox Herman.
and again
Why Stephanopolous? He should be a Romanov, lost cousin of the Tsars, eh?
Perhaps the next step in the evolution of Herman? http://www.dailymail.co.uk/news/article-2191541/Bad-boy-Craze-dogshaming-sweeps-internet--cats-arent-safe-owners-scorn-either.html?ICO=most_read_module
Quote from: NicholasMyra on August 26, 2012, 05:12:18 PMOld!
Refuses to dine with gay neighborsEats filet mignon at rich man's house instead
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The Most Memorable Music Moments in TV This Year So Far
December 04, 2013 via Pepsi
15 Most Memorable Music Moments in TV This Year So Far
Television is the perfect outlet to witness your favorite musical acts grab some much-deserved air time. This year was certainly eventful in that respect, with a number of award shows and specialty programming showcasing incredible performances and moments that simply couldn't be captured in a song on the radio. As the year winds down, we highlight 15 memorable music moments in TV that people will be talking about for years to come. From Justin Timberlake's stunning performance at the MTV Video Music Awards to Neil Patrick Harris wowing us at the Tony Awards, these are the musical moments that defined 2013.
1. Beyoncé Performs for the Super Bowl Halftime Show
The Super Bowl Halftime Show has become synonymous for being extravagant, an event that arguably rivals the Super Bowl itself. Beyoncé's appearance at this year's show may have been the best yet, as her 14-minute performance delivered in every way possible. From "Crazy in Love" to "Halo," she performed a medley of records from her catalog with style and grace, rarely missing a note while hitting every dance move onstage. Beyoncé even brought out former Destiny's Child members Kelly Rowland and Michelle Williams to join her in performing "Bootylicious," "Independent Women Part 1" and "Single Ladies (Put a Ring on It)." Add in grandiose fireworks as well as an elaborate stage and lighting setup, and Beyoncé's performance was an incredible moment that millions of Americans will remember years from now. Click here to watch Beyoncé perform for the Super Bowl Halftime Show.
2. Bruno Mars, Rihanna, Ziggy Marley & More Pay Tribute to Bob Marley at the Grammy Awards
The Grammy Awards are the perfect time to celebrate the stars of today and likewise pay tribute to the influential artists who paved the way for them. That was the case at this year's Grammys, where a number of esteemed artists took the stage to honor the late-great Bob Marley. Bruno Mars, Rihanna, Sting, as well as Marley's sons Ziggy and Damian we're all present to celebrate Bob's contributions to music as they performed his 1980 record "Could You Be Loved." Ziggy and Rihanna playfully went back and forth for the first verse while Damian turned up the reggae flair for his part. By song's end it was clear the crowd loved every second of the performance. Click here to watch Bruno Mars, Rihanna and more pay tribute to Bob Marley at the Grammy Awards.
3. Kanye West Performs "Black Skinhead" on Saturday Night Live
Information was very sparse leading up to the release of Kanye West's album Yeezus, until the Chicago rapper appeared on Saturday Night Live in late May to perform "New Slaves" and "Black Skinhead" from his sixth solo project. While both songs were aggressive in nature, it was "Black Skinhead" that caught a lot of attention for its pulsing drum pattern and distorted melody. Dressed in all black, West put on an intense performance as he screamed at the top of his lungs while subliminal messages flickered in the background. For anyone who second guessed Kanye's ability to expand his sound, this was a thrilling wake up call. Watch Kanye West's live performance of "Black Skinhead" on SNL above.
4. Charlie Wilson Receives BET's Lifetime Achievement Award and Performs
Charlie Wilson may not the be the biggest household name for Generation Y, but the 60-year-old R&B singer has established an illustrious career that spans four decades and countless hit singles as a solo artist and a member of The Gap Band to boot. This all culminated in June when Wilson received the Lifetime Achievement Award at the BET Awards. Fittingly, the honorary singer took to the stage to perform a medley of songs alongside collaborators Snoop Dogg, Pharrell Williams and Justin Timberlake. The vibrant performance was the clear highlight of the BET Awards, with Charlie Wilson showing why he's still a crooning force to be reckoned with onstage. Click here to watch Charlie Wilson's performance at the BET Awards.
5. Neil Patrick Harris' Opening Performance at the Tony Awards
Ever since a teenage Neil Patrick Harris impressed viewers as the star of Doogie Howser, M.D. in the late 1980s, it was clear that he was born to entertain, whether that be on the big screen, small screen or on a stage. For his fourth time in five years hosting the Tony Awards, Harris surely outdid himself this year with his opening number. The seven-minute performance highlighted his multitalented background as he sang, danced, played guitar and performed an illusion that caught audience members by surprise. Dare we say it: This was a Tony Award-winning performance from the 40-year-old actor. Click here to watch Neil Patrick Harris perform at the Tony Awards.
6. Little Big Town & Keith Urban Cover Fleetwood Mac's "The Chain" at CMT Music Awards
Performing a cover of a song is a difficult task to undertake considering the ridicule and disappointment that comes if the rendition is done poorly. With that in mind, Little Big Town put their reputation on the line during this year's CMT Music Awards where they performed Fleetwood Mac's 1977 record "The Chain." Not only did they cover the song with amazing execution, they brought the classic song new life. Their remarkable performance also included a killer guitar solo from seasoned artist Keith Urban, who rose from underneath the stage like he was ready to conquer the world. Little Big Town certainly set the bar here for other artists that plan on covering songs on live television. Click here to watch Little Big Town and Keith Urban perform "The Chain" at the CMT Music Awards.
7. Paramore Perform "Still Into You" at Teen Choice Awards
The Teen Choice Awards may cater more toward pop acts like Justin Bieber, Taylor Swift, and One Direction, but the show this year became a full-on rock concert when Paramore hit the stage to perform their single "Still Into You." Sporting a cute orange bob cut, lead vocalist Hayley Williams pulled the audience members in with her radiant stage presence, even doing a jig during the song's bridge. Paramore would go on to win the Best Rock Group award, and rightfully so given their notable performance here. Click here to watch Paramore perform "Still Into You" at the Teen Choice Awards.
8. Justin Timberlake Receives MTV's Video Vanguard Music Award and Performs
Justin Timberlake has already had an impressive 2013 with two chart-topping albums in The 20/20 Experience and The 20/20 Experience 2 of 2, as well as a highly successful headlining tour with rapper Jay Z. At this year's MTV Video Music Awards, the 32-year-old singer added to his accolades as he was awarded the Michael Jackson Video Vanguard Award. Before receiving the award from an ecstatic Jimmy Fallon, Timberlake put on a performance of a lifetime. Opening with "Take Back the Night," Timberlake ran through a number of his biggest hits including "SexyBack," "My Love," "Cry Me a River," and "Mirrors." He was a class act throughout the 15-minute performance, hitting every vocal note and dance move while the crowd watched in awe. If anyone were to hold the title of "The King of Pop" in 2013, it would be Justin Timberlake. Click here to watch Justin Timberlake perform at the MTV Video Music Awards.
9. 'N Sync Reunite at MTV Video Music Awards and Perform
Justin Timberlake's amazing performance at the MTV Video Music Awards can't be discussed without also mentioning the onstage reunion of 'N Sync. One of the biggest boy bands in pop history at the turn of the century, the group performed a medley of songs including "Gone," "Bye Bye Bye," and "Girlfriend." While the performance looks to be a one-off moment for 'N Sync, who also reunited for the first time in a decade, it was still great to see them recapture the flare that melted hearts in the past. Click here to watch 'N Sync perform at the MTV Video Music Awards.
10. The Weeknd Performs "Pretty" on Jimmy Kimmel Live!
The Weeknd did a remarkable job early on in his career keeping a low profile as an artist. The mysteriousness of his motives and music made for a compelling storyline for fans that hung on his every word. However, this past year the 23-year-old singer from Toronto, Canada began to break out of his private shell, first by gracing the cover of Complex Magazine and soon after embarking on a national tour to promote his debut studio album Kiss Land. During the early stages of the tour The Weeknd went on Jimmy Kimmel Live! to perform his new single "Pretty." His performance on the late-night show marked his first television appearance, which is incredible to think about considering he's been one of pop's most in-demand artists over the last few years. The packed crowd present at the Sony Outdoor Stage soaked in his emotional lyrics, where many also captured the memorable performance from The Weeknd on their phones. Watch The Weeknd perform "Pretty" on Jimmy Kimmel Live! here.
11. Lorde Performs "Royals" on Late Night with Jimmy Fallon
While Lorde's hit single "Royals" is highlighted by a teenage narrative that mocks the lavish lifestyle of stars, it's clear the 16-year-old singer from New Zealand was born for the spotlight. Lorde proved this notion to be true when she appeared on Late Night with Jimmy Fallon to perform "Royals," which recently hit number one on the Billboard Hot 100 chart. It was her U.S. television debut, and she handled herself with a charming poise that felt like she had done this a hundred times before. There was nothing flashy about her appearance as she wore a plain white dress and a few sizable rings on her fingers, but the impressive performance captivated the audience from beginning to end. Click here to watch Lorde perform "Royals on Late Night with Jimmy Fallon.
12. Kanye West Settles Dispute with Jimmy Kimmel on Jimmy Kimmel Live!
An apparent feud occurred online between Kanye West and Jimmy Kimmel when the late-night comedy show host spoofed an interview of the Chicago rapper with BBC Radio 1's Zane Lowe. After finding out about the video spoof, West sent out a number of comments on Twitter insulting Kimmel, who responded with more jokes that only fueled the flame. A few weeks later West appeared on Jimmy Kimmel Live! to settle his dispute with the show's host. West expressed his disappointment with the way the media portrays him, and explained that he still strives for greatness even though it may bring negativity. It made for some compelling television, as Kimmel's demo ratings hit an all-time high with Kanye's appearance. Watch Kanye West's interview on Jimmy Kimmel Live! above.
13. MC Lyte Receives the I Am Hip Hop Award at the BET Hip Hop Awards
MC Lyte received the I Am Hip Hop Award at this year's BET Hip Hop Awards for her contributions to the genre and the culture at large. Releasing her first album Lyte as a Rock in 1988 at the age of 17, Lyte is considered a pioneer in hip-hop for opening doors for other female performers. MC Lyte became the eighth individual to receive the I Am Hip Hop Award, as well as the first female solo artist to earn the honor since the BET Hip Hop Awards began in 2006. An inspiration to many, Lyte explained during her acceptance speech that she hopes her legacy continues. "To all of the female MC's who have come after me, keep the dream alive," she said. "I am with you." Click here to watch MC Lyte receive the I Am Hip Hop Award.


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This story was updated at 1:05 p.m. March 27.
A lockdown of DuVal High School in Lanham was lifted Wednesday afternoon after police said they investigated a "generic report" of a gun at the school.
Cpl. Larry Johnson, a county police spokesman, said the lockdown was a "precautionary measure," and that no weapons were found during their search of the building. Johnson said police had received a call spurring the investigation, but had no details as to whether it was from somebody at the school or a resident. "It was nothing catastrophic," Johnson said. "We were just in the school making sure everything is cool, and from the info we're getting from the scene, it looks that way."
County school spokesman Briant Coleman said the Prince George's County Police Department asked DuVal principal Alice Swift-Howard to place the school on lockdown. He said he had no further details about the matter, except that "all students and staff are safe." After the lockdown was lifted at around 12:15 p.m., Coleman described the incident as a "false alarm."
"We don't know if there was an incident in the community or if it's just a routine investigation," Coleman said.


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This is a bit of a pain but super simple to solve, I made this ible to show you how to put your ports exactly where you need them, on the front of your iMac. Just see what a difference a bit of sugru can make :)
Headphone extension cable
USB extension cable (male to female) (these are easy to find online or in a local store - I bought 25cm (10") cables - they are the perfect length for this project)
Masking tape
Why sugru is good for this:
1: bonds to Aluminium brilliantly :)
2: bonds to most other materials
3: you can remove sugru from most non porous surfaces without leaving any marks - take a look at this ible to see how
Step 1: TRUST IN THE TAPE
The success of this instructable depends a lot on the use of tape.
To ensure that the inputs stay straight and do not move while the sugru is curing, it is important to tape the wire in place on the back of the computer.
Also, once the inputs are sugru'd in place, it is important to tape them in place, as the wires often offers resistance and try to pull the inputs out of place. Use tape to help hold the hack in place while it cures.
We found a strong masking tape worked best. It may not be as strong as duct tape but it wont leave marks on your beautiful iMac.
What a Eye Sore. No thank you, I like my iMac just the way it is...
*though a USB hub works too* :)
Just wish apple would get on the stupid USB 3 bandwagon by now. Feeling the need for speed here. Though on my 6 year old mac its not going to make much of a difference...
My point of accessibility is that you shouldn't have to get used to it... Although hubs do work well, if I spend that much on a computer, I expect it to have a well thought out design, be faster than any computer that costs less, and be able to do anything I throw at it. Mac fails all of those. I spent $400 on a new laptop for my niece, $50 on more RAM, and I spent 2 hours getting it fine tuned for her. It now runs faster than all of her friend's MacBook pros. Just sayin... ;)
My top 5 reasons to not like apple products:
1. Price- really, apple could be doing much better on this part, as nowhere but apple does it cost $200 to upgrade RAM.
2. Expandability. Apple products are designed to look nice, but not really user expandable.
3. Lockdown- really, get on the open source vibe apple.... grr.
4. Late getting standards- blu ray and USB 3 are becoming the norm on computers- apple thinks thunderbolt will do but it just cant..
5. Not supported half as much as PC's. Self explanatory.
What I would consider a nice apple product (I really want a laptop so this is all gonna be for it)- Low-ish price, some nice post i7 processor, support for an unhealthy amount of RAM (I would max out 16gb), and a good video card.
And I dont even play hardcore 3d games. More like angry birds. Oh and X-plane 10.
your second is they aren't "expandable"? hmm. i have plenty of devices plugged into my USB and Thunderbolt ports.
third, "Lockdown- really, get on the open source vibe apple" perhaps you aren't aware of OS X's open-source roots, apple's contributions to BSD or many other projects. try http://www.apple.com/opensource/
standards like blu ray? really? when everyone else is moving to digital delivery. usb3 hardly has much traction, and apple isn't the only one behind thunderbolt, intel is pushing it hard too. PS. you can plug an external blu-ray drive into your mac and it will work just fine. mine is plugged into my "non-expandable" USB2 port.
"no supported half as much as pcs" really? what does this statement even mean. supported, by who?
Not just for ram- why do you think apple has $60 BILLION in revenue? Because they charge so much. An 8gb ram upgrade is $200 on apple and less than $50 from crucial. As for hardware, why should it cost $2500 for a laptop with the EXACT SAME SPECS as a $500 one? Surely, apple is not using some space age polymer for their products that costs the world to produce.
Expandability as in 3rd party upgrades. Upgrading a hard drive on a mac is harder than you think. As for any other parts, they are only produced BY APPLE, so good luck finding a replacement...
Heard of iOS? Its in major lockdown. I would also be in heaven if apple decided users might actually want to change settings...
Everyone else is moving to digital delivery? Yeah, in like 5 years when the rest of us have the bandwidth for it and everyone is connected. That idea sucks when you go outside. Sure, apple can get rid of the drive- most people dont use em anymore. They should at least be SUPPORTING standards with external products. Thunderbolt, while being pushed by intel, I havn't really seen it on any PCs lately0
Not supported half as much as PCs? Try and find software. I can find LOADs of FREE great working software for a PC, but try it on a mac and youre gonna end up with nothing or $50 out of pocket.
I really dont want to start this war about apple and macs. I do know my stuff when it comes to mac pricing, and theirs sucks. Many times, for a consumer, the decision comes to spending $2000 for $400 for a nice windows laptop. Most people are not going to spend $2000 on something they see is equivalent to a PC
everyone knows apple doesn't use "space age polymer". they use fairy dust.
do you walk into a BMW dealership and tell them you can buy a chevy for 1/2 the price and demand they price match? after all they both sell cars with 4 wheels and use gasoline! the "EXACT SAME SPECS"!
erm, i've upgraded hard drives on macs since the early 80's. if you're competent with a screw driver you won't have much trouble. yes, i pulled the glass off my 24" imac to upgrade the 500G drive to a 1TB. wasn't that hard. certainly not for most of the people who probably hang out on instructables. ;) as for spare mac parts, there are plenty of 3rd party suppliers. try ifixit, ebay, owc, etc.
iOS. lockdown. maybe you didn't know you could download xcode for free from apple and write your own apps. and then there's this little thing called jailbreaking. there's also a settings app that lets you change plenty of settings. ohhh, wait, do you mean obnoxious themes? yeah. jailbreak and you can do those too.
sorry you won't have decent bandwidth for 5 more years. still on your dial-up aol account? and this is apple's fault how? maybe you can move to somewhere that you can get broadband. what isn't apple supporting with external products? i already mentioned that you can hook up a blu-ray drive via usb. speaking of, you didn't see it on too many PC's when the iMac was first released, it took PC's a while to catch up to Apple on that one. along with the 3.5" floppy. heck, even the mouse. Macs had been using mice since 1984, took PC's more than a few years to catch up, all that DOS ya'knkow.
oh yes. the billions of apps argument. well, we know how many of those LOADs of apps are quality software. there's a reason people pay a few hundred dollars for MS Office vs. using Notepad.
"you get what you pay for"
well, you've already admitted you don't want to pay for hardware, no surprise you won't pay for software either. but again, how is this apple's problem and not your own? infact most of your arguments seem to be centered around the fact that you won't pay for apple products, but as you opened with, apple has $60billion in revenue. so apparently there are quite a few people who believe that their products are worth the price paid. whatever Apple is doing wrong, they're taking it all the way to the bank!
I agree with all of your anti Mac reasons, but my #1 is that they think too much and there isn't a way to change default actions very easily, so for instance, if I plug my camera in, iPhoto takes over and there's no way to change that if I want it to do something else.
On the contrary, I believe you can (when you first use iphoto) choose it not to open automatically. And I also think there is a checkbox to open automatically when a camera is found. So apple is flexible, but most people aren't going to take the time to find wherever the checkbox is.
Anyways I'm holding out until Ivy Bridge goes popular (or I think haswell is the next big intel processor group, i5 is getting a bit older in computer years.)
Regarding iPhoto, maybe they've changed it, but as of a year or two ago, there wasn't a easy way to turn that off. To this day, one of my media production friends constantly complains about it, and he's pretty computer savy, so if there were an easy way, I think he would have found it by now. ;)
Regarding processors, that's great if you're willing to wait, but don't go rushing out to buy it the day it comes out... Wait for a month or two and see what kind of reputation it's getting. I have some friends who couldn't wait for the i7 to come out, and they got it immediately after it came out for their laptops, and they've regretted it ever since.
people who trash macs are just jealous they don't own one.
In response to everyone, I am not afraid of a Mac vs PC debate, but let me be clear on my point of view:
I am not trying to convert Mac lovers to PC (as a matter of fact, I will buy a Mac before I will buy windows 8), everyone is entitled to their own opinion, and I respect everyone equally in that. My personal view point is that I hate the OS, it's too expensive for what you get, and the security isn't that great. (and like I said, I used to do data recovery for a living... I've cracked into both macs and pcs more times than I would like to admit... So please don't try to argue with me on that one... I'll probably win.) Just a warning to those of you that are Mac lovers out there, please drop the "everyone who disagrees with us is stupid and doesn't know what the heck their talking about" additude... Obviously some of us do know what we're talking about, and that additude just makes you seem stuck up and arrogant. Not every one of you has that additude, but enough of you do to give the rest of you a bad name.
I'm sorry if I have hurt anyone's feelings, but that's what I believe.
i welcome you to crack into my file vault protected mac any day. i'm sure someone with your "mad skillz" will have no problem. but hey, you didn't even know about the image capture app...
I'm sorry, but when you get a job recovering data for a branch of the US government (or any other major government for that matter), you can start to insult me... Until then... Please keep the discussion respectful.
"I've cracked into both macs and pcs more times than I would like to admit..."
"recovering" a non-protected system doesn't count as "cracking". anyone can plug in a hard drive and do a dd.
And not just anyone can or will do data recovery- thus why people have the job as a living.
(sorry to throw you into this thegeeke!!!!)
for someone claiming to be "computer savvy" yet having no knowledge of simple mac administration (using image capture to control automated photo loading) i find his boasting to be slightly exaggerated and i'm calling him out on it.
maybe he can write an instructable on how to "crack" a mac and share his skills with the rest of us.
I refuse to help just anyone learn to "crack", I need to trust their judgement first, and even then I can only show certain things due to an agreement with my previous employer, therefore I strongly refuse to write an ible on how to "crack" into a Mac or any other OS. You should be ashamed to even suggest it.
@astroboy907, don't worry about it... I got myself into it. :)
Obviously there are times when you have to change procedure, but this is a generic process. :)
So flip off, make drive read only, copy, and then get the data off the working copy. But the password stuff is the hardest part I'll bet.
And I dont really need instructions, as instructables is probably not the *best* place we want to spread step by step computer breakin instructions ;)
You are recovering a computer for evidence. You find the computer (let's make it easy and say it's a desktop), but it is turned on and is at the login screen. What do you do, and why do you do it that way? (This would be the same for both windows and Mac, and I'm trusting you not to use Google. I'm not sure if this is out there anyway... It probably is, but you might have to dig for it.)
Thunderbolt is proprietary. As its not anywhere close to universal, usb 3 is the best its gonna get. Just because its fast doesnt mean its functional
And really, how many of us NEED 12 core processing??


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Yemen Coffee Bonanza (and Tea! and Indonesians ...)
Yemen Coffee Bonanza! It's a first; we currently have 4 distinct Yemeni coffee selections at Sweet Maria's, and one tea. Yes, tea ... coffee tea ... made from the dried skins of the coffee fruit! It's called Yemen Qishr Tea and is a very unique experience. These Yemeni coffee lots are clean and balanced compared to selections from the past, and at least 2 (Ismaili and Sharasi) result in some of the best Single Origin Espresso I have had this year! Yemen Mokha Ismaili is spicy, lush, velvety, and a bit more earthy than the others. It's the best Ismaili in 2 years. Yemen Mokha Mattari has winey fruit and chocolate, my favorite brewed cup. Yemen Mokha Sharasi is a lot I found in Yemen last November, delicate, fruited, refined, and an incredible SO espresso. We have other arrivals too: Indonesia Flores "Jade" is unlike the previous offers from this tiny island, rustic, intense, more Sumatra-like. Speaking of Sumatra, we have a great Sumatra Organic Mandheling that cups better than the numbers indicate. Read the review. And here's robusta you can drink as a French Press brew! (Although we still recommend it chiefly for espresso blend use: India Robusta- Jeelan Estate Sitara.Â