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"AFC vs. NFC for the NFL Championship - Sunday, January 27, 2002"
Yes, that's right - January 27, 2002, the original date of Super Bowl XXXVI, is printed on this poster. This first-printing of the Official Tickets poster was completed just days before September 11, when the terrorist attacks caused the NFL to push back the big game to February 3, 2002. The publisher, Action Images, had already shipped several hundred copies of this printing before the date change was made, but suspended shipments immediately as they prepared a reprinting. Therefore, this original-date version is in EXTREMELY limited supply. Super Bowl poster collectors will want to grab up a copy before they're gone. Note: the second printing, with the corrected date, is now available. Click here for more information.
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Halifax Citadel National Historic Site
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You people down there, you dont show up to games, and when you do, you hold up "suck for luck" signs and chant "we want orton!" at practice.
now in march - during a week day - you are out there with paper bags over your heads protesting?? HAHA!
when people say they dont want to play in Miami do you really think its ALL b/c of IRELAND??
what about the fact the home games feel like away games, the media sucks and is clueless plus jumps on every player and coaches back at the first sign of some some rough times, the idiots that call into to wqam are more clueless than jets fans half the time.
i have friends who are jets fans, pats fans, giants fans, boys fans ETC. and NONE OF THEM, NONE OF THEM have as much negative things to say about our roster/coaches/chances as my fellow dolphins fans.
its a DISGRACE.
we are not ONE of the worst franchises - we are now THE WORST. b/c not only is our team not winning - but our fan base is a laughin stock of clowns and fools.


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- TED Book Chat
- New York, NY
- United States
This conversation is closed.
Live Q&A today at 3:30 Eastern: How is the developing brain of a child like the emerging global brain of the Internet?
"The Internet, like the developing brain of a child, is in a rapid phase of growth and change. This means that just as we must be mindful in how we nurture our children's minds, we must also pay careful attention to how we develop our global brain."
In conjunction with her TED Book, author and Webby Awards founder Tiffany Shlain has put together an excellent short film explaining her fascinating ideas about how brain development in kids parallels the development of the Internet.
You can watch the 10 minute film here: http://youtu.be/zLp-edwiGUU
And then read the book:
Kindle: http://www.amazon.com/dp/B00A30S24S
iOS: https://itunes.apple.com/us/book/brain-power/id576233926?ls=1
And here's an article in the Harvard Business Review about the project:
Author Tiffany Shlain ( http://www.ted.com/profiles/91428 ) will be joining us here for a one-hour Q&A Tuesday, December 4th, from 3:30-4:30pm. Mark your calendars!
Dec 4 2012: afraid I am finding this format very confusing
Dec 4 2012: Irene, how can I help clarify the format? Would it help if you switch your "Sort By" setting to "Oldest First", so you can read questions/responses in the order they were published?
Dec 4 2012: FYI: I've found that you also have to keep "refreshing" the url !Dec 4 2012: I'm afraid our time is almost up. Tiffany, thank you so much for taking the time to share your thoughts with us. I look forward to seeing what you create next! :)
To our participants, thank you as always for sharing your excellent questions. We hope to see you again soon for the next TED book chat!
Dec 4 2012: Thank Aja! you are terrific! Very cool way to engage. :)
Helen Situ
Dec 4 2012: Sometimes people worry that the internet may be negatively affecting our brains and connection to one another, what are your thoughts on it?
- +1
Dec 4 2012: great point. I think as with any technology there are good things and bad.... one good framework when thinking of technology and the internet is that it is just "an extension of us." we are good, bad and everything in between...and as with anything..if you over do it..it's not great. The reason my family and i started doing our weekly unplugging one day a week is because it was 'too much" technology.. I didn't need a neuroscientist to tell me that it wasn't good for my brain..because my head was hurting at night if i was at a screen until i slept. Now i dont' bring the cell phone or my laptop into my bedroom. I need to let my mind unwind. So as much as I LOVE technology and all the new ideas I am exposed to and new people I am connected to, I also know I need to turn it out too.Dec 4 2012: On the main topic of the book/film…. what would be your ideal future for this developing "mind" of the internet? Would it have any characteristics that it doesn't currently have? Do any existing networks achieve the sorts of deep, meaningful thoughts and connections that you'd like to see?
Dec 4 2012: It's been proven throughout history that innovation occurs when you get the most people from dif. perspectives thinking about a problem. Matt Ridley outlined this beautifully in his book "The Rational Optimist" where he talked about how innovation usually happened in cities where there were the møst folks from dif. backgrounds very close together. The ideal future of the developing internet is when everyone who wants to be online is online, and we have collaborative tools to bring people together from all dif. parts of the world to solve problems. We are just at the beginning of what i feel people will look back as the "Age of Collaboration." That's the "thinking" part of the future i would love...i also believe we are being awash in oxytocin ("love/collaboration/sharing hormone" in the brain) with all these links, clicks, posts, text....i think empathy will only increase as we get more connected...
Dec 4 2012: we 'just' need better tools to improve the quality of the connections. A 'like' or '+' button is just not enough.
Dec 4 2012: Dirk, can you elaborate? Would love more thoughts on building better tools.Dec 4 2012: how did your children (and your computer science) husband respond to the idea to unplug? any resistance?
Jim Daly
Dec 4 2012: I understand that your short film 'Brain Power' is part of a series you're working on. What's the meta-theme of the series, and how does 'Brain Power' fit into it? What will the other films be about?
- +1
Dec 4 2012: "Brain Power" is part of a film series we are doing called "Let it Ripple: Mobile Films for Global Change." In these films we try to tackle topics that connect us all. Our first one was "A Declaration of Interdependence," the second about the importance of "Engagement" in society, and this one on the importance of nurturing and strengthening children's brains on the global brain of the internet. We will be doing three of these a year. 15 in all. All these films at their core, explore what it means to be human.Dec 4 2012: I feel like so much of what's uninteresting and less-valuable online is there because marketing, sales, and other forces are looking to turn users into customers/followers/etc. Does the developing brain have any comparable functions competing for our attention, that make it more difficult to focus on the best information/connections?
Dec 4 2012: Great question! I need to mull on that one.Dec 4 2012: Something that I found myself wondering as I watched and read… as you explain, the main way we're able to "shape" our children's brains is by choosing what to focus on with them, what to draw their attention to. The rest is naturally pruned away as they age. But does the same thing happen online? What's the process for pruning online information and connections that aren't useful or interesting?
Dec 4 2012: Great question. If you think about sites we no longer visit, people we no longer follow, things we unsubscribe to..we are pruning.Dec 4 2012: Tiffany, I remember that pivotal moment you showed in Connected where you saw how your "connectedness" with the world was impacting the connectedness with those closest to you (your daughters, husband, close friends and extended family).
Is there a similar ah-ha moment recently as a parent while you were working on Brain Power, specifically in working/nurturing children?
Dec 4 2012: yes. I remember the exact moment. Originally when we were working on "Brain Power" it was just focusing on how to best nurture children's brains. We were talking to this brilliant neuroscience Dr. Patricia Kuhl (she has a great TED Talk) and she says, "the goal is with children is to get all the different parts of the brain connected. They are born with 100 billion neurons but the connections between those neurons are not there yet. She explained how your interacting with them creates those connections. " a big lightbulb went off. this is like the internet. We only have 2 billion people online. We must try to get everyone online in order to see it's full potential." A lot of the neuroscientists talk about the "first 2000 days" of a childs brain being extremely imp. to set the foundation for the future. I realized we are in that first "2000 days" of the internet's growth and we need to be just as mindful how we are growing and shaping it.
Dec 4 2012: Wow. That put such weight to it! We are talking about fundamental changes in history just as we are impacting our children by either engaging them in intentional parenting....or not.
Dec 4 2012: What evidence supports classifying the internet within "the first 2000 days?" More importantly, what would signify to you, Tiffany, that the internet has reached full maturation? Is it possible that the total content and connection size of the Internet would only continue to increase, remaining in a perpetual sensorimotor/preoperational stage of development?
Helen Situ
Dec 4 2012: How did you get so many submissions from around the world for Brain Power?
- +1
Dec 4 2012: We have a fantastic community who participates in what we call our "Cloud Films". "Brain Power" is our third film and each new one we do, we receive more submissions. We are just about to do a new call for entries, and I would love for you to join is. A great way to stay posted on our process and calls for entries is both our website www.letitripple.org and our facebook page "Connected the film" ...Dec 4 2012: what are some of the policy and spiritual challenges raised by this book? is my brain undeveloped because I don't relate to this formal...it is more like a chat and I have had difficulty seeing if there is a developing thread
Dec 4 2012: Your brain is not underdeveloped :)*
This is an unusual format for me too. but loving the interaction and questions.
Highly recommend you download the book. It's all in threads in there:)*
I feel like in Cinderella when the carriage is going to turn into a pumpkin in 1 minute! there is only 1 min left for this live Q & A.Dec 4 2012: Aja, at the moment Facebook and similarities work not that dissimilar from old mailbox/bbs systems that exited in the 1980s. FB has added a like button and everything looks flasher.but the quality of connections still often relies on RL meeting to gather depth, don't you think? also the interaction is largely text-based and asynchronous.
That said, I've never been to Second Life. Interaction in face-tface situations is much more comlex than what we are doing here. here we have to leave much of how the other orients to us, to our imagination.
Dec 4 2012: good point. i can't wait until video and moving images are really incorporated more into ...well, everything. When you are "with' someone live, half the info you get is from what they say, the other half from body language. We need to use both R & L hemisphere when interacting! I also think they need to add a "Dissimilar to you" button on twitter.Dec 4 2012: how do you see the link btw online and offline connections? Howard R talked long ago about the strengthening and connection-building effect of online communities. how do you experience that yourself?
Dec 4 2012: Great question. Both kinds of connections are important. I see this a lot when our "connected the film" facebook community comes to an live event. Nothing replaces the value of real life interaction.
Even with you. We met on Twitter as we both are interested in the same kind of ideas. Then when I told you I was coming to Europe you tweeted to a conference and made a talk/screening happen and I got to meet you in person. Love that. There needs to be a special word for when you meet someone you have only followed on twitter. I think "Twenchante" would work when we finally meet;)Dec 4 2012: Hi Tiffany,
What, in your opinion, could we each be doing to help shape a more developed internet? Is regularly going offline a part of this, or is it more in how we choose to spend our time when we are online?
Dec 4 2012: I def. thinking unplugging weekly is very important to try. I promise you will love it.
And then when we are online, we need to be mindful that everyone we follow is influencing the connections in your brain. So we need to be mindful of who and what ideas and connections we making happen. That's all for us personally..and our minds of course, plug into this larger global collection of minds.
On that front, I feel very strongly that we need to bridge the digital divide so we can get as many dif. perspectives and wisdom participating in these global conversations.
People also need to be paying attention to policies that are happening that can be the reshape the global brain in the wrong way. There is a mtg happening (ITU) which is making some major decisions in info flow onilne.. You can watch this video to check out how to understand what is happening and how to get involved. https://make-dev.mozillalabs.com/en-US/projects/roll-your-own-itu-activism-video/
I know that's a big list. I unpack it more clearly in the TEDBook which i think you would really enjoy reading. (and it has less typos;)
Dec 4 2012: Thank you, this is good food for thought.Dec 4 2012: I like that Robert's question touches on being mindful of the way we connect in addition to understanding the importance of disconnecting!
What is the next film we can expect in the Let It Ripple Series, Tiffany?Dec 4 2012: Tiffany, Have you seen others taking technology breaks (tech shabbats)? If so what has the response been? I am so thankful that you encouraged me to take them. Do you find it challenging to schedule those rests around your busy schedule and how technology centered your medium and craft is?
Dec 4 2012: I love that you do them too now. That has been the best part of these films is sharing that i unplug and seeing other people try it. (Everyone, here I recommend trying it!) Do I find it challenging to do ..no. I just have to plan. Now most close friends and family know they can't get in touch with me Friday night to sat. sundown (ish) but everyone adapts and then suddenly you have this day to focus on your family or just yourself...It is good to let your mind go into a dif. mode one day a week. With my kids we are pulling out all sorts of games (a 70's version of CLUE i found in my garage and scrabble.) We spend more time outside. it's all good.Dec 4 2012: Is this film and book related to your great feature-length film CONNECTED directly or indirectly?
Dec 4 2012: and how do you see your films emerging from or related to the Webby Awards?Dec 4 2012: Definitely related to our film "Connected." The whole new film series "Let it Ripple" is ideas from "Connected" in action. The climax of "connected" asks what is the potential of everyone being online? what can we do with that? (the film also goes into the good, the bad and the potential of all this connectedness and a very personal story interwoven..) you can watch the trailer at www.connectedthefilm.com
Dec 4 2012: and the Webbys? were you making films while you worked on the Webbys?Dec 4 2012: I saw that at the end of the film, you get a "customized" version if you are a non-profit. How does one do that and have you made any yet for non-profits? How do they use these customized films? What an amazing idea!
Dec 4 2012: agree. that is a great idea!Dec 4 2012: You can just go to our site www.letitripple.org and find out how to easily have one made for your nonprofit for free. We are already making around 25 versions of "Brain Power." Organizations that are interesting in child development, internet policy, education, tech, are all getting them made. It feels so great for our team to make these free films for nonprofits who do such imp. work but often don't have media to get their message out. The nonprofits will then use the film (which looks like it's their film with their call to action, url and logo at the end) for events, fundraising, email campaigns, etc.Dec 4 2012: is there a nook version of the book?
Dec 4 2012: Yes:) thanks Dirk!Dec 4 2012: How long did it take to complete the TED book? I love that the TED book deepens our engagement with these important topics of early brain development!
Dec 4 2012: This is a great question. I was Tiffany's editor on the book, and we really took a non-linear film and adapted it into a linear narrative that expands on the ideas in the film.Dec 4 2012: What is the most (or one of the most ;) interesting things you learned in the research & making of both the film & Brain Power Ted Book that you didn't know before?
Dec 4 2012: I think learning about neuroscience really help me think about the growth of the internet in a new way. The way I can contextualize what acts like PIPA and SOPA would have done to the web to constrict the free flow of information. Also in terms of neuroscience and my children. We have a 3 year old who is in that first "2000" of life when her brain is most malleable. And learning that her mind has more connections than the entire internet, def. blew my mind. I learned a lot of things that stimulate her brain's growth. Eye contact is great. and Making her laugh. These were things I did before but let's just say now, i do a lot more.
Dec 4 2012: When my 7 year old daughter watched it she pushed her fist in the air when learning that her bran has more connections that of an adultDec 4 2012: this is not live with moving images, correct?
Dec 4 2012: This is live right now. Ask away:)Dec 4 2012: and in relation to Aja's question, how do you strike the balance and manage (your) children's use of the internet and other activities considering the draw of screens is so great to children (and adults)?
Dec 4 2012: My family and I unplug once a week together as a family. We call it our "technology shabbats" it's really changed our lives. it's been around 2 years that we have been doing it. We also had a screening of "Brain Power" along with Rebecca Randall from "Commonsense Media" which was terrific. That website/org. has fantastic guidelines when thinking of our kids and screens.Dec 4 2012: Really glad I am able to type fast right now;) It's interesting to think that one's fingers are the conduits to our communicating our thinking;)Dec 4 2012: I'd love to hear more about this, as well. :) I loved the description in the book of your "Technology Shabbat". Do you have to lock up your laptops/phones/devices? I don't know how I'd be able to resist checking in with the online world for a full 24 hours!Dec 4 2012: We've also been fortunate enough to chat with Sherry Turkle and Howard Rheingold here on TED Conversations, both of whom are mentioned in your book. Do the three of you ever get together, and if so, what do you talk about? And do you keep your phones switched off? ;)
Dec 4 2012: Actually we do. Howard is a dear friend and mentor. We take walks in the hills of Mill Valley together and talk about this stuff. Sherry is fantastic too. Sherry and I talk about unplugging. One of these days we want to co-author something together.Dec 4 2012: Love your incorporation of found footage, animation, the submitted videos and great music in Brain Power making complex ideas entertaining and engaging. Do you always create work in this way?
Dec 4 2012: First, thank you:) This new style of filmmaking really evolves my earlier style. I couldn't afford to go to film school and often made films but recutting together old movies. That style still informs my film today. We now do original animation for our films but we rarely shoot. Adding this new component of having people all over the world send us videos is very exciting for our film team. We recently wrote a "Cloud Filmmaking Manifesto" which talks about our process. We are making free customized versions of our 10 minute film "Brain Power" for non profits.Dec 4 2012: Tiffany, do you see events such as Syria's shutdown as an example of toxic stress to the Internet?
Dec 4 2012: Yes! That is a great example. The government is trying to stop the flow of information and connection between people! an exact parallel.Dec 4 2012: How long did it take you to make BRAIN POWER including the research & making the film?
Dec 4 2012: Hmm..My co-writers Prof. Ken Goldberg & Sawyer Steele and I started diving into research January of this year. I was approached to do the TEDBook in I believe April. So let's just say 2012 was about "Brain Power";)
Comment deleted
Dec 4 2012: You're in it! Just write and submit your question the way you did right here. :)Dec 4 2012: Welcome Tiffany!
Dec 4 2012: Hello! Happy to be here:)Dec 4 2012: Hello all, and welcome to this live Q&A with author Tiffany Shlain! Tiffany, thank you for joining us, your "Brain Power" book and film have some fascinating thoughts for those of us who spend so much time online. :)
To start off, I wanted to ask… the book/film format for Brain Power was a new one for me, very cool! How did you get started as a filmmaker/author? Is this work you've always wanted to do, or did you find yourself unexpectedly drawn to it? Do you plan to use this book/film format for future projects?
Dec 4 2012: Hello Aja!
This was a very exciting process:) We were just finalizing the script when I was asked to do a TED Book. It was exciting put all the research into context in the book.Dec 4 2012: I definitely think I would like to think about film/book format together for the future. What is so great about the TEDBooks is that we could put film clips into the book in the iPAD version. It is a filmmakers playground to take a script and unpack it with visuals.Dec 2 2012: The Internet is a global system of interconnected computer networks that use the standard Internet protocol suite (often called TCP/IP, although not all applications use TCP) to serve billions of users worldwide.
whereas: In a typical human the cerebral cortex (the largest part) is estimated to contain 15–33 billion neurons, each connected by synapses to several thousand other neurons.
In the above there is a simularity. From a central point each send billions of messages. However, while the internet has only one purpose and utilizes a standard protocol ... the brain serves many funtions, seperate and combined actions, and reflexes. The brain has the ability to grow, adjust, revise, react, and recall.
I do not see the internet as a global brain ... I see it more like a home library with vast resources. It is also a form of communications which is global.
After watching the clip I was left with the questions of how can we develop both better. Since this was in the title I was lookuing forward to the answer or suggestions.
Dec 4 2012: Tiffany Shlain, the author here. Glad you saw the 10 minute film Brain Power. Highly recommend reading the TEDBook which I do go into details on how to nurture and strengthen both: children's brains and the global brain of the internet.Dec 2 2012: I find this to be an extremely important issue.
I am not sure though if the comparison of the world wide web to a child's brain is adequate. It might lead us to some strange conclusions. The rationale behind it seems valid at first sight, but I would not go too far with it. I am mostly worried about some kind of control over the net.
While it is of utmost importance when it comes to babies, the net should grow on its own. It is nobody's baby after all. If we start limiting its possibilities or "bring it up" in a certain way, we will simply destroy it.
Ultimately, the responsibility is on the side of the user. A well brought up, mindful and cultural.
Dec 4 2012: As with any metaphor, our goal is to think of a framework. In the book and the film I go into how the internet is in the "same stage of development" as a toddler. Not that the internet is a toddler. There are definitely things we can learn from neuroscience strategies on best ways to strengthen children's brains from zero to 5 that we can apply as a framework in thinking about the internet. For example, for children, it's key that you get all the different parts of the brain connected for the most insight thoughts to happen. I also believe this is true with the internet. We only have over 2 billion people online. We need to get everyone online who wants to be online in order to have the most collaborative "insightful" thoughts online. I go into this more in the TEDBook:)*Dec 1 2012: From the dawn of life to genetic codes to brains to the internet - it is all the same process of networked interactions where the whole is greater than the sum of it's parts. Scientists tell us all networks self sustain in a realm that is not overly chaotic and subject to collapse, yet not overly stable and therefore not adaptable and able to grow. So you want a "child's world" and an internet, that is not overly chaotic and not overly stable. I guess in terms of what I heard in your video there is an optimum level of stress - not too much and not too little, and the same can hold in your internet networks/interactions.


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Old-Fashioned Ribbon Candy
Old-Fashioned Hand-Cut Ribbon Candy Is as Beautiful as It Is Tasty
Old-Fashioned Ribbon Candy
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Dear Ms. Vicki,
I met a man on a website about two months ago and we started to chat and to send emails to each other. His name is Col. Miller Brown. He is 43 years old and stationed in Yemen.
He said that he applied for his retirement before his deployment and by the end of the year 2012, he got his papers. He put me as his next of kin on the papers. It was with my agreement and maybe it was my mistake.
A few days later, I got an official-sounding email from the United Nations that I have to send a copy of my passport and two passport photographs to them. I did what they asked. Two days later, I got another email from them that I have to make payment for his retirement -- $3,000.
When I told my boyfriend that I don't have so much money and I asked him if he cannot pay for it by himself, he said that he is in a war region and he has no access to his funds. Is that true or false?
The other thing what I would like to know is, if I pay for his retirement and he will be free to leave a war region, must he go straight to the USA or is he free to go wherever he wants? I am afraid that it might be a scam.
Dear Sally,
Please, please tell me you did not send any money to this person. This is a big scam. I get tons of letters like yours every week from people who want to believe that the person they care about is really in the military. The information you have already provided to the scam artist puts your financial life at risk.
Clearly, this person is not in the U.S. military. No one has to pay a fee to retire from the U.S. military. A retirement ceremony is a source of pride, esteem and accomplishment, not an exit fee. The United Nations does not have any authority over the U.S. military.
Your gut is telling you the right answer: This is a scam. Here are some other ways to tell if the person you have met online is really in the military or whether he is running a scam:
1. No military email address. All servicemembers have email addresses that end in .mil, as in @army.mil or @usmc.mil, or @navy.mil.
2. Secret mission. If he tells you he is on a secret mission, ask yourself: If it's so secret, why is he telling you?
3. Asks for money. Scammers have all kinds of reasons they need your money -- to help him retire, to be able to come back for R&R (rest and relaxation), to return home from deployment. There are others reasons out there, but the bottom line is if he asks you to give him money to help him with the military in any way, he is lying!
4. No name of unit. Even if he is deployed overseas, he is stationed somewhere with someone. Which unit is he in? Where is his unit located when he is not deployed? Unit information is public information available on the internet.
5. High rank. If the person says he is a colonel, a general, an admiral, a senior NCO or in some other high position, it is doubtful that he or she is cruising the internet for strangers -- much less asking for money.
If one or any of these things is true, this person is most likely a scam artist -- not the love of your life. Please don't send any money to this address and stop all communication with these people immediately! They will steal every dime you have.
Change your phone number, email address, other social network addresses, and any of your financial account passwords and account number too. Get a free credit report now and register for the service that alerts you if anyone applies for credit in your name. Please stay in touch and let me know what happens.
Ms. Vicki
Related Topics
|Family and Spouse Ask Ms. Vicki
Ms. Vicki is a native of Dallas, is married to an active-duty Soldier and has three sons. She has a Master's of Science in Social Work from the University of Louisville, is a Licensed Clinical Social Worker and currently works as a therapist with military servicemembers and their families. She provides services for a wide array of concerns such as combat stress, PTSD, couples and marital problems, depression, grief and loss, stress and coping.
Ms. Vicki also writes an advice column "Dear Ms. Vicki" that appears in the Washington Times, the Fort Campbell Courier and the Heidelberg Herald Post. Ms. Vicki also hosts an internet radio show and blogs on her community site with the Washington Times. If you want to ask Ms. Vicki for advice about your military life, please email her at email@example.com.


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Pop Chart Lab pours hours upon hours of research and meticulous design into every print they create, with the promise of providing an accurate and artistic visual guide to, well, everything. The Compendious Coffee Chart examines the many methods of crafting wondrous, live-giving java—from Chemex contraptions to French presses to the automatic drip. It even explores additions like steamed milk and chocolate, making you a full-blown barista from the comfort of home.
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The New York Stock Exchange will become part of an Atlanta-based collection of securities exchanges and clearing houses, if a merger announced Thursday morning gets approved by regulators and shareholders.
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BEGIN:VCALENDAR VERSION:2.0 PRODID:-//22.214.171.124//NONSGML kigkonsult.se iCalcreator 2.20// CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:OCL X-WR-CALDESC:Orthodox News | Jurisdictional Unity | Transparency X-FROM-URL:http://ocl.org X-WR-TIMEZONE:America/New_York BEGIN:VTIMEZONE TZID:America/New_York X-LIC-LOCATION:America/New_York BEGIN:STANDARD DTSTART:20151101T020000 TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST END:STANDARD BEGIN:DAYLIGHT DTSTART:20150308T020000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 RDATE:20160313T020000 TZNAME:EDT END:DAYLIGHT END:VTIMEZONE BEGIN:VEVENT UID:firstname.lastname@example.com DTSTAMP:20150903T110042Z CATEGORIES;LANGUAGE=en-US:Concert\,Fundraisers CONTACT:Subdeacon Robert\; (313) 204-5103 \; firstname.lastname@example.com. DESCRIPTION:
The program will consist of hymns to the Theotokos sung during the liturgical year performed by the Orthodox Choir of Metropolitan Detroi t conducted by Matushka Vickie Kopistiansky\, artistic director. "We're v ery excited that it will be a great concert\, and we look forward to suppo rting a great charity like IOCC\," Subdeacon Robert A. Mitchell\, preside nt of the COCC\, said.\n
The concert will be open to the general public as well as Orthodox Christi ans free of charge. Donations will be collected t o support the IOCC. An afterglow will follow the concert. For a map and di rections to the church\, visit the St. Mary website at\n
IOCC is the official humanitarian aid agency of the Assembly of Canonical Orthodox Bi shops in North and Central America. Since its inception in 1992\, IOCC has delivered more than $400 million in relief and development programs to fa milies and communities in 50 countries. For further information\, contact IOCC at (877) 803-IOCC (4622) or email@example.com.\n
The COCC (http://www.coccdetroit.com) is a 55-year-old clerg y and lay association that represents various canonical Orthodox churches in metropolitan Detroit and sponsors a variety of programs in the areas of worship\, fellowship\, charity\, education and outreach. For further info rmation\, contact Subdeacon Robert at (313) 204-5103 or email@example.com .\n
The Orth odox Choir is composed of volunteer singers from Orthodox parish choirs th roughout metropolitan Detroit. In addition to special concerts\, the choir sings an annual series of Vespers services during the five Sundays of Ort hodox Great Lent sponsored by the COCC and served by members of the Orthod ox Clergy Brotherhood of St. John Chrysostom of Metropolitan Detroit.\n
For further information\, contact Matushka Vickie at (313) 366-0677.< /p> DTSTART;TZID=America/New_York:20121104T230000 DTEND;TZID=America/New_York:20121105T020000 LOCATION:Antiochian Orthodox Basilica of St. Mary @ 18100 Merriman Rd\, Liv onia\, MI 48152\, USA SEQUENCE:0 SUMMARY:Council of Orthodox Christian Churches\, Benefit Concert: Livonia\, MI URL:http://ocl.org/event/council-of-orthodox-christian-churches-benefit-con cert-livonia-mi/ X-TAGS;LANGUAGE=en-US:benefit concert\,IOCC END:VEVENT END:VCALENDAR


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An industrial-era water tower, adorned with eyes some years ago by volunteers and well-known as the Owl, keeps an eye on things. Ijams is known for its "owl prowls."
Mead's Quarry itself, filled with water for decades, is an attractive fishing spot.
In a once-forgotten forest in a an even longer-forgotten quarry site, signs of new activity: a temporary banner for last month's Outdoor KnoxFest, and a permanent marker describing the site, under the heading "Nature Takes Over."
It may be an irony that nature's popularity is most obvious in the parking lots that access it; Ijams' administrators say they have never been so busy as they are this year.
One of the most interesting aspects of Ijams' recent expansion, in the Ross Quarry section, is a peculiar structure known as the Keyhole. Constructed during the industrial era for purposes unknown, it's Knoxville's modern stonehenge. Huge limestone blocks, left there decades ago, make this different from other nature walks.
An old masonry train trestle, still used by CSX, is part of the Third Creek Bike Trail. Wooden bridges cross Third Creek itself, along this original section of the trail, ideal for contemplation. Now about 40 years old, this short stretch from just west of Tyson Park to the West High School area, between Kingston Pike and Sutherland Avenue, was Knoxville's first greenway.
Not all of Ijams' patrons are hippies or extreme sportsmen; careful to avoid too much sun, ladies walk their grateful dogs.
The professionally designed Knoxville Skatepark is located adjacent to Tyson Park. Yes, helmets are strictly required; a sign sternly warns of a $25 fine.
A boy traverses the bike trail's longest bridge, a zigzag span over a large swampy area.
Especially popular among UT families, Tyson Park's playground stays pretty lively.
Men fish near the mouth of Third Creek.


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Hang tight!
Recipe by Tara Salerno
"Spectacular Fourth of July Dessert! Present at night with a couple of sparklers for the best effect. Can make with shortcake mix, too."
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1 (18.25 ounce) package
yellow cake mix
1 (8 ounce) container
frozen whipped topping, thawed
1 pint
blueberries, rinsed and drained
2 pints
fresh strawberries, rinsed and sliced
This cake was GONE at the end of the day. It's very, light. I used the golden butter recipe. Also used the COOL WHIPPED FROSTING on same website. All you do is add a small package of instant vanilla pudding, 1 cup of milk, and 1 tsp vanilla to the 8 oz cool whip. You combine the pudding mix with milk and vanilla, and mix until smooth. Gently fold in cool whip until no streaks. This topping is also good for a fruit dip. It's a little more firm than just plain cool whip. I was concerned about letting the cake sit out all day with a cool whip topping, but that wasn't a problem. Everyone was able to see how festive it was -- then chowed down on it later. I will fix this every July 4th -- now a tradition in our family.
Not a bad cake. I took someones advice who reviewed this cake as well an added a packet of instant vanilla pudding to the whipped topping. Definatley gave it a better taste and a firmer texture. Would make this again with the added pudding!
201 Ratings
I make a similar cake every year for the 4th of July. Instead of a plain yellow cake, I use a white one and make it a jello cake, then frost with the cool whip and decorate with berries. Turns an ok cake into a winner!!
A nice cake and very pretty to look at!
I used chocolate cake instead of yellow just because I think that chocolate cake with Cool Whip is one of the best flavors in the world!
Don't try to skimp on the whipped cream like I did. Use the whole container, believe me its well worth it. And make sure the cake is COMPLETELY cooled before you frost it, otherwise you'll end up with a runny, sloppy mess. Although a very good tasting mess.
A very yummy and easy (plus fast) cake to do.
I have used a similar recipe for years. I use a white cake mix. Poke holes in cake with a wooden skewer and pour 1 package prepared instant red jello, such as rasberry, cherry or strawberry over cake. Prepare only with 1 cup of hot water cooled. Frost with real whipped cream or Cool Whip. Deocorate with Blueberries for the stars and ether strawberries or red rasberries for the stripes. I bake it for the 4th of July and always get raves. Very Moist.
It's good but too much cake and not enough strawberries. The next time I made it I sliced the cake in half longways to make a layer. I poured strawberry glaze and put a layer of sliced strawberries and blueberries. Placed the top layer of cake and finished with whipped cream, blueberries and strawberries to make look like a flag. My family and friends loved it!
This is a fun and festive dessert that is easy to make. I ended up only needing about half of the fruit called for. Because my strawberries were so big, I needed to slice the strawberries thinner (in half and then in thirds) to be able to make 6 red stripes. If you have to slice the strawberries more than just in half, it helps to slice off some of the inside flesh. This helps the strawberries to lie flat so that only the outer red skin shows hiding the paler fleshy part. Nothing terribly unique about the taste, but still yummy enough and very patriotic. Kids loved it and can help in the decorating process.
This is one of my favorite recipes during this time of the year. The only thing that I do differently is to use an already made pound cake (we like Sara Lee). We decorate it the same way...just smaller (since there are only 3 of us.) Thanks for a reminder and a great recipe.
* Percent Daily Values are based on a 2,000 calorie diet.
Red, White and Blue Strawberry Shortcake
Serving Size: 1/18 of a recipe
Servings Per Recipe: 18
Amount Per Serving
Calories: 182
Calories from Fat: 50
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Delicious recipes, party ideas, and cooking tips! Get a year of Allrecipes magazine for $7.99!
This patriotic cake is perfect for Fourth of July picnics and parties.
A fun, easy, and patriotic breakfast.
See how to make strawberry shortcake with airy buttermilk biscuits.


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This fantastic energy efficient desk lamp combines sleek contemporary style with advanced technology.
The clean and simple Koncept Gen 3 Equo LED desk lamp produces 40% more light than Gen 2 models and features improved design and feather-light adjustability. The floating arm raises or lowers effortlessly while the tilting head can rotate 180 degrees and is detachable for easy repair or replacement. Slide your finger along the strip to dim gradually, or touch anywhere on the strip to jump directly to any brightness, including off. The energy efficient LEDs produce a warm light that will last for up to 50,000 hours.
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text: Weed graps some folks different then others. So that is a concern believe me I have seen it do some disastrous things as a high school coach. But if you feel as a scout what you have gained from interviews that the reward out ways the risk you get this guy in the third. I would not be shocked if someone jumps on him in the late 2nd.


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Welcome to Reebok CrossFit Lifespark
Become part of the fittest Community in Dubai - hard work has never been so much fun!
We believe that fitness is essential to a great life. The key difference between us and most other fitness programmes is in our all-inclusive approach to health, fitness, vitality and life. To us this is 'Total Life Fitness'.
We are performance-based fitness professionals. Performance is simply doing what you want to do, be it a triathlon or chasing your kids. Fitness has less to do with WHAT you are doing and more to do with HOW you are able to do it. We use CrossFit as our method of achieving great fitness.
Once you change your focus to performance, you will be stronger, faster, more flexible and have better endurance. You will also lose fat and become more muscular and toned, have more energy, sleep better and activities that were once difficult will become easier.
We focus on teaching movement techniques and skills, physical conditioning and the development of healthy workouts and eating habits. Most importantly we, as coaches and as a community, support you when things get tough.


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I am able to create lists in Facebook. Is it possible to apply a set of privacy setting for each list?
Take the 2-minute tour ×
Web Applications Stack Exchange is a question and answer site for power users of web applications. It's 100% free, no registration required.
I'm not sure if that's what you mean with "privacy setting for each list" (the lists are not public so you're the only one that can see them) but you can use the lists in your privacy settings to show/hide things for/from people on these lists.
You can then enter persons or lists in the "Hide this from" textbox as well as the textbox that appears when you select "Specific people" in the "Make this visible to these people" dropbox.


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Midweight compression fabrication increases support and helps with muscle vibration. Graduated compression. Strategically placed mesh in heat zones. Flat-lock stitching. PlayDry and anti-microbial.
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Providing a meaningful education that guarantees all students the same opportunities and resources to attain the knowledge, values, skills, and experience necessary to function as responsible and productive members of society.
Our Staff Cares
Find out why our staff are willing to bear the weight and responsibility of teaching and guiding. Our staff does their best to be there for each student.
Annual Events
From trips to the Beach, Holiday Events, Back to School, Olympics Day, Talent Shows, Disneyland Grad Nite, students have a wide range of activities to get involved.


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Get Your Grill On
Knowing exactly when to take your meat off the grill has never been easier. Just insert the iGrill probe into the meat you'd like to track, let the free app know what you're tracking and leave your iGrill by the side of the grill (or smoker).
Monitor Your Progress
Now you can get back to your guests, go inside and watch the game or work on other dishes. Keep a close watch on the temperature progression of your meat right from your smart device and receive an alert once your food is ready to enjoy.
Savor Perfection
Your friends and family will be left wondering how you fired up such a delicious meal without getting stuck by the grill. You'll never want to cook any other way and with the iGrill, you won't have to.


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BRET has been successfully applied to the study of GPCR homo- and heterodimerization as well as receptor/β-arrestin interactions involved in receptor desensitisation and trafficking in mammalian cells. The main advantage of BRET is that it allows protein-protein interactions to be monitored in real-time, in their correct location, in live cells. In this application note read about the basic considerations for a BRET assay when studying protein interactions in living cells.
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Showing 1-24 of 1,889 items found in Shopping
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Ziemer Gallery
Featuring Watercolors of Larry Ziemer, plus other artists
Zeza Hair Salon & Day Spa
With 40 years of combined experience we at Zeza strive to enhance your look and overall feel, while using the finest quality European products.
Zealous Art Studio
This exceptional art gallery features local artists - paintings, photography, ceramics, woodworking and much more. Also offered are children's art classes as well as pottery classes. Open: Monday thru Saturday: 10 am - 7 pm.
Sustainability and style are the mission at this international fashion giant.
Zales The Diamond Store Outlet
High quality jewelry and accessories.
Your Heart's Desire
This mall has collectibles, antiques, primitives, and locally handmade goods. On West Frankfort Main Street. Only 10 miles south of Rend Lake.
CITY:West Frankfort
Your Core Being
A Wellness Collaborative featuring a Yoga studio with classes scheduled six days a week, private individual and small group yoga; individual holistic health coaching and workshops; massage and Reiki therapy; and skincare with licensed esthetician. Shop the wellness market for items that serve your wellness, including local products and artisan items, organic and Fair Trade products and gift items.Open: Tuesday thru Thursday: 11 am to 6 pm; Friday: 11 am to 5 pm; Saturday: 10 am to 1 pm
You Gotta Be Kidding
One of the many unique, specialty shops that call Galena home, find collectibles: such as, Coke/Pepsi memorabilia, Barbie dolls, banks, signs and hard-to-find gifts.
Yorktown Center
Shop Von Maur, Carson Pirie Scott, JCPenney, Target, and nearly 150 specialty shops. Kids love the Yorktown Express train and the free Treehouse Adventure Play Area. Experience exciting tastes, styles and entertainment at The Shops On Butterfield.
Yoder's Lamps & Antiques
A shop full of antiques and 30+ dealers, plus a large inventory of antique oil and gas lamps. Repair and parts are available for antique and modern oil and gas lamps. Authorized Aladdin Lamp dealer and repair.
Yoder's Homestead Shop & Furniture
Beautiful locally crafted Amish furniture in walnut, oak, quarter-sawn, cherry, hickory and maple. You can also find quilts and locally made jams, jellies and popcorn.
YM boutique
Opening its doors in the summer of 2014, owner Jessica Fong was looking to spread her love of fashion to those in the Chicagoland area. Located in the heart of Downtown Aurora, YM boutique is quickly becoming known as a must see fashion destination. YM boutique strives to bring the Midwest the latest trends first and people everywhere are looking to YM for those fashion finds you won't see anywhere else. Come see for yourself why YM boutique is a must stop destination for all your fashion needs.
Yellow Creek Quilt Designs
Gift and quilt shop offering fabric, notions, quilting accessories, and many specialty gift items including wine accessories, wall art, Willow Tree and Williraye Studio. Open: Monday thru Thursday: 11 am - 7 pm; Friday: 11 am - 5 pm; Saturday: 10 am - 5 pm.
CITY:Pearl City
Yaeger's Farm Market
Farm products available for purchase include plants, fresh fruits and vegetables, plus a wide variety of Amish jams and jellies. A pumpkin patch and corn maze are featured in the fall.
Wyldewood Cellars Winery
Wyldewood Cellars, a family-owned and operated winery, started in Kansas and expanded here to Illinois, produces over 40 different types of wine. What began as a small Elderberry winery has blossomed into an internationally recognized and awarded winery. Since their beginning, they have won over 400 international awards for their Elderberry Wines, Grape Wines, as well as their other varietals. Wyldewood Cellars Spiced Elderberry Wine was featured and served at the 2002 Winter Olympics in Utah and was awarded the Best Non-Grape Wine in North and Latin America, among many other Gold Medals. Sample and purchase their gourmet wines at their Illinois location where they produce, bottle and label their family's nostalgic wine.
CITY:Saint Joseph
Wray's Fruit Farm
Stop for u-pick strawberries and apples in season, or purchase other fruit products such as apple butter.
CITY:Clay City
World's Largest Knitting Needles and Crochet Hook
The World's Largest Knitting Needles and Crochet Hook are located inside The Yarn Studio in downtown Casey, Illinois. In order to make it in to the Guinness Book of World Records shop owner, Jeanette Huisinga, had to knit and crochet a 10X10 square with the largest tools. Knitting Needles are 13ft .75in and 25 pounds each. Crochet Hook measures at 6ft. 1.5in and weight is 9lbs.
Words, Wicks, and Wood
Come explore our wide variety of books or just simply find the book you've been looking for, as you discover the numerous titles available at this fine bookstore.
Words of Wisdom
A Christian book and gift shop.
Woolly Mammoth Antiques
We are a curiosity cabinet of antiques & oddities resurrected from the past. Located in the heart of the Andersonville neighborhood of Chicago, IL, our store is a great place to find strange old stuff! We invite you to browse through our large selection to find the perfect gifts for your home. Stop by today!
Wool & Company
Wool and Company is a full service knitting and crochet store with an extensive gift selection. We spread our love of knitting in a fun, creative and informative way.
CITY:St. Charles
Woodstock Harley Davidson
The Midwest Superstore, Woodstock Harley Davidson, where you can purchase as well as rent one of their new Harley-Davidsons for the day, week, or special events. Everything from street rods to V-rods. Many special events to enjoy too.
Woodfield Mall
One of Illinois' top tourist destination, anchored by Nordstrom, Macy's, Lord & Taylor, Sears, and JC Penney. Woodfield has nearly 300 stores, restaurants, and specialty shops all under one roof.
Furniture from primitives to Victorian, advertising, signs, country accessories and more. Call ahead.


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Raymond William Froggatt (also known as "Froggy") was born in Bordesley Green, Birmingham, UK on 13 November 1941, and is a British songwriter and singer. Froggatt began performing rock and roll in the early 1960s and soon gained a reputation for his well-crafted songs and exciting live performances. Froggattâ[][]s band, initially known as the Buccaneers, later Monopoly and ultimately The Raymond Froggatt Band, and whose bassist was Louis Clark of ELO and Hooked on Classics fame, were signed by Polydor in 1964 but success eluded them, although the Dave Clark Five had a #7 hit with Froggyâ[][]s "Red Balloon" in 1968. His own version of the song, under the title "Callow la Vita", reached #3 in the Netherlands. Another Froggy song, "Big Ship", was a #8 hit for Cliff Richard in 1969. In the 1970s the band was managed by Don Arden, hoping to break into the United States music scene, but the experience led to the collapse of the band. Froggy has a large live following: his unique mix of country music and rock and roll is popular with audiences all over the world. Froggyâ[][]s band now comprises long-time colleague Hartley Cain on guitar, bassist Jamie Davey and Rosie Heywood on drums.
This area is intended for discussion only. If you have a question about your order, or require customer service you can get in touch via our Customer Service Area. Comments enquiring about existing orders, including personal details, or with questions will be deleted.


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"The reason I like to see theater is seeing a compelling story on stage," said actor and director Veronica Reyes.
Reyes, currently living and working in New York City, is the co-director of "Martha Speaks," a children's theater production based on the book series by Susan Meddaugh and subsequent PBS television show. It's the story of a family dog who gains the ability to speak after eating alphabet soup.
While "Martha" may not sound like one of the compelling stories that makes Reyes love going to the theater, the director insists it is.
"It's not just about a dog who learns how to speak," said Reyes. "... It changes the relationship between the dog and her best friend and the family."
Reyes, along with her co-director Nick Salvidar, is with Theatreworks USA, a New York-based touring company specializing in theater for young audiences and their families. "Martha Speaks" makes a stop at the BlackRock Center for the Arts on Saturday afternoon for two performances.
Since 1961, Theatreworks has toured nationwide, presenting plays for young audiences. The company also aims to bring theater to underserved communities that otherwise may not have access to the performing arts.
Every summer, Theatreworks produces shows at the Lucille Lortel Theatre on the Upper West Side. The company gives out 15,000 tickets for the plays free of charge.
"[Theatreworks'] mission is to put up a show in New York City where people from all over can come and see," said Reyes, who has participated in the free summer theater program for the last two years. "For many of [the children], it's the first time they've seen theater ... It's an incredible program they have. They keep theater accessible."
In addition to free summer theater, Theatreworks tours 16 shows each season from its repertoire of 133 plays and musicals. According to Reyes, every play gets a mini-tour at schools in New York City. Finally, the production goes out on a national tour, usually for about six months.
This is the second tour for "Martha Speaks." For its first run, which wrapped in the fall, Reyes and Salvidar served as associate and assistant director respectively.
Salvidar is a graduate of the University of Central Florida in Orlando where he studied acting. After college, Salvidar was one of the winners of the Student Directing Fellowship at the Kennedy Center American College Theater Festival. It was after meeting several of the professionals involved in the festival that Salvidar decided to pursue directing professionally.
Since then, the 23-year-old said he has directed a wide variety of shows including those aimed at children.
"I've had a little bit of experience doing theater for young audiences before," said Salvidar. "The difference between the adults and the kids: if you're not being honest with the adult audiences, adults sit there politely. If you're not being honest with the kids, [they] just start playing with their shoes ..."
"Children won't buy anything that's false," added actor Joel Sparks, who portrays Dad in the show. "They won't believe anything that's not real. You have to approach it as being very real."
Sparks, a College Park native, graduated last year from the University of Michigan's musical theater program.
According to Sparks, Salvidar and Reyes "Martha Speaks" will keep both young audiences and their parents engaged.
"[Theatreworks] tries to make the show crafted so that the moms and the dads and the teachers are all having a good time," Salvidar said.
The play, which runs approximately 50 minutes, certainly has a message for its young viewers.
"There are a lot of great lessons," said Reyes. "This dog has learned how to speak and is really trying to find her voice. She's trying to find how to speak up for herself and how to stand up ... It speaks to a bullying theme. How do you stand up for yourself?"
While the lessons may appeal to the children, a lot of the comedy is aimed at their parents.
"It is definitely a well-rounded show in that there is a little bit of everything for everyone no matter what age," Sparks said.
"Martha is written to be this ... comedian," added Salvidar. "She's written as a Bette Midler or a Joy Behar [or] Rosie O'Donnell. She's written as a very smart comedian."
Besides its humor and its good intentions, "Martha Speaks" has got something else that makes it a true Theatreworks production.
"There's always a lot of heart," said Reyes. "That's what I love about Theatreworks ... It's the heart of the show."


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Home > Electronics > Cameras & Video Cameras > Video Cameras > Air Pro WIFI Action Camera Bundle with 8GB Micro SD Card
Air Pro WIFI Action Camera Bundle with 8GB Micro SD Card
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Air Pro WIFI Action Camera Bundle with 8GB Micro SD Card
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|1080p: 1920x1080 (16:9), 30 FPS. 720p: 1280x720 (16:9), 30 FPS/60 FPS (Slow Motion). 960p: 1280x960 (4:3), 30 FPS
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|Full HD-1080p/30 FPS/127 FoV OR HD-720p/60 FPS/170 FoV
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Air Pro WIFI Action Camera Bundle with 8GB Micro SD Card
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Interpretive Handbook
82528 :
14-3-3 Protein, Spinal Fluid
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
The 14-3-3 proteins are a group of highly conserved proteins composed of several isoforms that are involved in the regulation of protein phosphorylation and mitogen-activated protein kinase pathways. They exist in vivo as dimers of the various isoforms with apparent molecular mass of 30 kDa on sodium dodecyl sulfate polyacrylamide gel electrophoresis and 60 kDa on gel chromatography. Sequence homology among the various isoforms ranges from 22% to100%. The beta, gamma, and theta isoforms are found in tissues of the nervous system.
Detectable 14-3-3 protein in the cerebrospinal fluid (CSF) is indicative of substantial, relatively rapid neuronal destruction. Increased CSF concentrations of 14-3-3 proteins have been described in patients with various forms of Creutzfeldt-Jakob disease (CJD), some other rapidly progressive dementias, and a large range of other vascular, inflammatory, neoplastic, and metabolic central nervous system (CNS) disorders (see Cautions), which can be associated with significant and rapid neuronal destruction.
The main clinical use of 14-3-3 measurements is in the differential diagnosis of dementia, in particular to distinguish CJD and its variants from other dementias. The most common forms of dementia (progressive multi-infarct dementia and Alzheimer disease) are uncommonly associated with elevated CSF levels of 14-3-3, presumably because of their slow pace of progression.
CJD is an incurable neurodegenerative disease caused by accumulation of self-catalytically malfolded endogenous prion proteins in the CNS. Its cause is most commonly sporadic, but it can be inherited (mutations that predispose to malfolding) or acquired (iatrogenic transmission by infected human tissues or tissue extracts or surgical procedures, or by ingestion of some animal products that contain malfolded prion proteins).
The diagnosis of CJD is highly complex and involves clinical history and neurologic examination, electroencephalographs (EEG), magnetic resonance imaging (MRI), and exclusion of other possible causes of dementia, in addition to CSF examination. Several, slightly different scoring systems are in use to integrate these parameters into a final diagnosis of possible, probable, or definite CJD. The most widely accepted of these scoring systems is the WHO set of diagnostic criteria for sporadic CJD from 1998 (see Interpretation).
Useful For Suggests clinical disorders or settings where the test may be helpful
Supporting, in conjunction with other tests, a diagnosis of Creutzfeldt-Jakob disease in patients with rapidly progressive dementia when other neurodegenerative conditions have been excluded.
Interpretation Provides information to assist in interpretation of the test results
A concentration of 14-3-3 protein in cerebrospinal fluid (CSF) of > or =1.5 ng/mL supports the diagnosis of Creutzfeldt-Jakob disease (CJD) in patients who have been carefully preselected based on various diagnostic criteria. CSF 14-3-3 measurement is particularly helpful in sporadic CJD, where it is used as 1 of several diagnostic criteria.
Sporadic CJD World Health Organization (WHO) diagnostic criteria from 1998:
1. Definitive CJD:
-Neuropathological diagnosis by standard techniques AND/OR immunohistochemistry AND/OR Western blot confirmed protease-resistant prion protein AND/OR presence of scrapie-associated fibrils
2. Probable CJD:
-Progressive dementia
-At least 2 of the following symptoms:
--Myoclonus, pyramidal/extrapyramidal, visual or cerebellar, akinetic mutism
-Positive electroencephalographs (EEG) (periodic epileptiform discharges) AND/OR positive CSF 14-3-3 protein and <2 years disease duration
-No alternate diagnosis
3. Possible CJD:
-Progressive dementia
-At least 2 of the following symptoms:
--Myoclonus, pyramidal/extrapyramidal, visual or cerebellar, akinetic mutism
-No supportive EEG and <2 years disease duration
Recently proposed, but not yet universally accepted, amendments to these criteria center on including magnetic resonance imaging (MRI) high-signal abnormalities in caudate nucleus and/or putamen on diffusion-weighted imaging (DWI) or fluid attenuated inversion recovery (FLAIR) as diagnostic criteria for probable CJD.
The USA Center of Disease Control and Prevention supports these modified WHO criteria as of 2010 (http://www.cdc.gov/ncidod/dvrd/cjd/diagnostic_criteria.html).
There is no established role for 14-3-3 measurement in the diagnosis of acquired or inherited CJD.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Hemolyzed specimens will be rejected. Hemolysis causes falsely-elevated 14-3-3 results. The 14-3-3 concentrations in 82 visibly blood-tinged cerebrospinal fluid (CSF) specimens were up to 281 ng/mL, with 74 specimens (90.2%) showing levels above the cutoff.
In addition, specimens may be determined to be unsuitable for testing if any of the following conditions are observed:(1,2)
-Macroscopically hemorrhagi
-RBC counts >500 cells per mcL
-WBC counts >10 cells per mcL
The Mayo Clinic 14-3-3 assay is a quantitative assay for 14-3-3. All other assays are currently based on qualitative or semiquantitative assessment of 14-3-3 Western blots of CSF specimens. Results of diagnostic 14-3-3 studies performed in other laboratories, therefore, cannot be compared directly with the Mayo Clinic 14-3-3 test results. However, the published literature suggests comparable sensitivity and specificity ranges between the Mayo assay and Western blot assays.
Regardless of the method used, measurement of 14-3-3 protein in CSF should not be relied upon exclusively to establish the diagnosis of Creutzfeldt-Jakob disease (CJD). Increased concentrations of 14-3-3 protein in CSF have been described in a variety of central nervous system (CNS) diseases other than CJD that are associated with relative rapid (days to months, rather than months to years) destruction of significant amounts of CNS neuronal tissue. Published examples include: infectious encephalitides, transverse myelitis, stroke, intracerebral and subarachnoid hemorrhage, rapidly progressive vascular dementia, various metabolic and anoxic encephalopathies, severe acute CNS episodes of multiple sclerosis, cerebral vasculitides and angiopathies, mitochondrial encephalomyelopathies, CNS storage diseases, widespread or rapidly growing primary or secondary CNS and leptomeningeal tumors, and, rarely, Alzheimer disease and other primary dementias.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Normal: <1.5 ng/mL
Elevated: > or =1.5 ng/mL; compatible with, but not diagnostic of, Creutzfeldt-Jakob disease
Clinical References Provides recommendations for further in-depth reading of a clinical nature
1. Day IN, Thompson RJ: Levels of immunoreactive aldolase C, creatine kinase-BB, neuronal and non-neuronal enolase, and 14-3-3 protein in circulating human blood cells. Clin Chim Acta 1984;136:219-228
2. Collins S, Boyd A, Fletcher A, et al: Creutzfeldt-Jakob disease: diagnostic utility of 14-3-3 protein immunodetection in cerebrospinal fluid. J Clin Neurosci 2000;7:203-208
3. Preissner CM, Aksamit AJ, Parisi JE, Grebe SK: Development and validation of an immunochemiluminometric assay for 14-3-3 protein. Clin Chem 2009;55(S6):page A199; abstract D-149
4. Collins S, Boyd A, Fletcher A, et al: Creutzfeldt-Jakob disease: diagnostic utility of 14-3-3 protein immunodetection in cerebrospinal fluid. Clin Neuroscience 2000;7:203-208
5. Burkhard PR, Sanchez JC, Landis T, et al: CSF detection of the 14-3-3 protein in unselected patients with dementia. Neurology 2001;56:1528-1533
6. Aksamit AJ, Preissner CM, Homburger HA: Quantitation of 14-3-3 and neuron-specific enolase proteins in CSF in Creutzfeldt-Jakob disease. J Neurol 2001;57:728-730
7. Castellani RJ, Colucci M, Xie Z, et al: Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease. Neurology 2004;63:436-442


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Step 1: Materials
-sketchbook paper (18 x 12) 10 sheets
-one piece of black core foamboard (30 x 20)
2. Lights (I had two sets of white led rope lights about 9 or 10 ft. long left over from a xmas sale. As far as lights go here, you can use what you want but they need to have low watts because of the obvious fire hazard.)
- two sets of led rope lights
3. Tools
-Box cutter
-glue (Elmer's is fine)
-mounting screws and wire
-measuring tape
-hot glue gun or household cement (for gluing the foamboard)
-plastic zip ties
Hm, that doesn't sound like a very bad idea actually
Totally atractive. Something I'd show or make my friends ;) Thanks!
Hope to see you there.
Home Repair, Refurbishment, and New Projects
One small niggle: the rope light is hanging out of the bottom - wouldn't end-pieces to the foamboard box make it much tidier?
One large niggle: step two is very confusing. I worked it out from the photos, but the text wasn't much help. That step need a re-write, especially when you consider how many members have English as a second language.


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Chaos Head Episode 6
Category: Chaos Head
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Blacksmith Sangria Tub & Ladle
- Overview
Serve everything in style – from punch and lemonade to mixed drinks and sangria – with our handcrafted glass vessel. An iron stand elevates the deep bowl, whose unique imperfections are a trait of blown glass.
- 11.5" diameter, 17.5" high; holds 11 quarts.
- Wrought-iron stand with a mouth-blown glass bowl that has a patterned texture.
- Ladle handle made of cast aluminum with a bronze finish and stainless steel scoop.
- Catalog / Internet Only.
- Dimensions & Care
- Bowl Overall: 11.5" diameter, 17.5" high
- Ladle: 4" diameter, 16" long
- Stand: 11.5" diameter, 12.5" high
- Glass Bowl: 11" diameter, 13.5" high
- For use with cold beverages only.
- Hand-washing recommended.
- Shipping Info
This is a general shipping item.
View our Shipping Information
Customer Service - Shipping Information
Return Policy
At Pottery Barn, we take great pride in the quality and craftsmanship of our products. Attention to design, materials, safety and construction is our priority. We carefully inspect your order prior to shipment. Upon receipt, please inspect your purchase and notify us of any damage; we will arrange for a prompt replacement. If, within 7 days for Quick Ship upholstery and 30 days for all other products, you are dissatisfied for any reason, you may return your purchase for a refund of the merchandise value.
We cannot accept returns on monogrammed, personalized, special-order items, or on items damaged through normal wear and tear. We also cannot accept returns of final-sale items which are identified by a price which ends in .99.
For returns of items purchased from your Pottery Barn registry, we will gladly provide a refund or exchange for the merchandise within 90 days of your event or within 90 days of purchase, whichever date is later.
You may return merchandise through the mail for a refund or replacement. For detailed procedures for returning items through the mail, please contact Customer Service at 1.888.779.5176, 7 days a week, 5:00am - 9:00pm (PT).


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Series: Saturday Science Links (29 entries)
The biggest science stories of the week are reviewed.
The Resource Finder has powerful filtering features — check out the tutorial to learn more.
The biggest science stories of the week are reviewed.
In the early 1700s, Isaac Newton and Gottfried Wilhelm Leibniz famously disagreed about whether God periodically "corrected" the orbits of the planets. Why their disagreement matters for today's debates about God and evolution.
Evangelicals are skeptical of space exploration—but can pastors change this from the pulpit?
The former chair of the Harvard University physics department muses on how faith gives meaning to his scientific work.
The story of the Genesis Rock reminds us of how biblical and scientific accounts, despite their different purviews and purposes, remain inexorably linked in our understanding of origins.
Are black holes in trouble? Could life have come from space? What do we know about the religious lives of Indian scientists? Find the answers to these questions and more.
This week's news features volcanoes, skeletons, and stars, as well as a thought-provoking new book from InterVarsity press.
From science and religion blogs: quantum uncertainty and God, the remarkable fact that we have come to understand our place in the created order, and the role of theology in making wise choices about the use of technology.
God could have created a fertile planet miraculously in an instant, but when we look carefully at the physical evidence, it appears that the earth has a longer history as part of the universe.
Astronomers have many different methods for measuring the age of various objects in the universe, and they all support ages of billions of years, not thousands. Even if the assumptions of one or two methods were faulty, it is highly unlikely that all of the methods would be affected.
Over the next few months, with permission from Yale University Press, BioLogos will offer edited versions of chapters from John Polkinghorne's best books, Belief in God in an Age of Science and Theology in the Context of Science, in order to help readers delve more deeply into some of his most important ideas.
... I would exhort these, my fellow conservative evangelical shepherds and thinkers, to set aside all reticence and fear, emerge from anonymity, and storm the forum of discourse, engaging this most pressing matter with vigor, equanimity, and humility. In doing so, know upfront that there will be few handrails to guide; you will not be building upon an extensive precedence of published conservative thought.
The debate is often not about evidence, but about making sure that others do not transgress our interpretive boundaries and insist that we're wrong. We've bitten from the tree of knowledge and we love its taste.
In this excerpt from the book Delight in Creation: Scientists Share Their Work with the Church, astronomer Deborah Haarsma shares her excitement about recent findings about our universe from a Christian perspective.
Our desire to engage in gracious dialogue with fellow believers who reject biological evolution has been receiving increased attention in both the Christian and secular press. More importantly, we are being joined in this reconciling project by our brothers and sisters in Christ who have often been defined primarily as our "opponents".
This ongoing series written by historian Ted Davis begins with a brief synopsis of his personal background, and then goes on to reveal his passion for debunking "the now-common view that the history of science and Christianity is one of ongoing, inevitable conflict."
At a press conference on July 4, 2012, and with 99.99994% confidence (5 sigma), CERN announced the discovery of a particle consistent with that of a Higgs boson (a.k.a. "the God particle"). This is very exciting for elementary particle physicists. But what is the Higgs particle, and what is its meaning?
The discovery of the Higgs boson would certainly be a breakthrough for particle physics and cosmology, but would such a finding also radically redefine theology's understanding of God or challenge the existence of such a deity? Is there actually any theological or religious significance in Higgs physics at all?
Today we have a chance to witness a special moment in history as Venus transits across the disk of the Sun for people across the world to see. Not only is this process of discovery exciting for natural science, but it has profound theological ramifications as well.
I ask the question, "Why is the universe so special?" Now scientists don't like things to be special; we like things to be general, and our natural anticipation would have been that the universe is just a common specimen of what a universe might be like.


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I have compiled Android Source codes and get settings.apk now I wonder can I install that application on my phone ? When I try to do that my phone say "CAnnot install application" what can I do to install that application ?
Take the 2-minute tour ×
Android Enthusiasts Stack Exchange is a question and answer site for enthusiasts and power users of the Android operating system. It's 100% free, no registration required.
System application are odexed, which means the code part it extracted and kept separate and also some crucial parts of the application are kept in framework.jar. If you want to copy your freshly-compiled application to your phone, you have to deodex it first, which restores the missing parts and only then you may replace /system/Settings.apk with your new file. And, please, make sure you delete old /system/Settings.odex file, otherwise it won't work.
As usually, it's recommended to save old Settings.apk/odex files just in case when something goes wrong.


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My wonderful wife bought me a boatload of Sears Craftsman power tools a few years ago. One of the tools in the treasure chest was a belt sander. However, I wasn't really using the belt sander for large surfaces. I was mostly using it to clean up my rough cuts on small parts. To do this I would hold the belt sander with one hand and the part with the other. No too safe and not very controllable. Using scraps of junk lying around my garage, I decided to make a stand. Now I can use both hands to hold the part for better safety and accuracy.
I also designed this stand so that you can quickly remove the belt sander from the stand by unscrewing two wingnuts. But to be honest, since making this stand, I've rarely used the belt sander in the hand held mode.
I apologize for the lack of photos in this Instructable. I threw this stand together a long time ago. I can't disassemble it for new photos because it is glued together. This belt sander stand is linked to another Instructable I previously posted. http://www.instructables.com/id/Make-a-footswitch-become-a-monkey./
The stand was in one of those photos. Some Instructable viewers were interested in how I made this stand. So I decided to create this Instructable, after the fact.
Oh yeah, as commented in my other footswitch Instructable, this will only work on belt sanders with a trigger lock. Or if you're desperate you can always zip tie the trigger and make a footswitch.
Note, my belt sander is a Sears Craftsman Model 315. It is an older model and is no longer available from Sears. All belt sanders are different. Shape and dimensions differ especially in the handle/grip area. My model 315 has a very angular shaped enclosure with many flat surfaces. Flat surfaces made it easier to mount to a stand. Newer belt sanders are more organic in shape. (Can someone tell me why a power tool needs to look like the head of Alien?) So the method I used in this Instructable may or may not apply to your belt sander.
If you don't own a belt sander, you can always go to Sears and purchase a proper bench belt/sander:
They're reasonably priced and not much more expensive than a handheld belt sander.
This is an easy Instructable that you can do in one day.
You can put this together with basic tools:
Rock, Paper, Scissors
1.5" x 1.5" lumber (I think tradesmen call this 2x2 since they're half of a 2x4,)
1/2" thick plywood
Sheet rock screws
Wood glue
Plastic sheet
Silicone adhesive
Double sided tape
Transwarp drive
Vacuum cleaner nozzle attachment
2 Bolts, wingnuts and washers
Here is a picture of one that I made.
Hey great design! I like it more than my vertical configuration!
nice work guys! I sanded my knuckles lately (not part of my usual beauty regime) so I really appreciate this inspiration. I think vertical is better so you use the width of the belt but it needs a table face to rest the work on like the horizontal. I have a sander that my dad, brother and I share, man it's done some years, I remember it from little, will be great to give it a birthday with one of these.
I build it but it didnt turned out as well as yours :D
Great! : )
Curious though, it looks like the front of the sander is pointing down. Which means the belt is travelling up while grinding on it, a little iffy and harder to control.


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Janet Jackson, Transgender Documentary: Singer to Executive Produce 'Truth'
This summer, Janet Jackson will begin work on "Truth," a documentary about the transgender community. The pop star has signed on as executive producer, and she'll also handle on-camera interviews with those individuals featured in the film.
"All people are very


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1. An old record album cover or any other large sized cardstock or thin cardboard. (manilla folder works well, thank-you to commenters below)
2. Paper. This could be blank, lined, grapned, colored or anything else you'd like. For this specific project I used blank 8 1/2 x 14 copy paper, otherwise known as legal sized paper.
3. Thread that won't break, like embroidery thread. (it also must be a cotton, otherwise it will tend to cut the paper and through the binding holes. 100% cotton yarn works great as well, but you'll have to make the holes a couple times larger for binding.
4. Embroidery needle or other thick sized needle that will hold embroidery or bookbinding thread.
5. Thumb tack.
6. Ruler.
7. Pencil.
8. Large paper clips.
9. Butter knife or bone folder.
10. A paper-cutter or really good pair of scissors or a really sharp xacto knife or a box-cutter.
Optional materials:
-clear packing tape
-colored paper
-glue stick
-large bead
I always wanted to know how do make booksThanks
Here's http://www.utdallas.edu/~cantrell/ee4301/epaper.gif a terrible gif image of the front of a sheet :p
As it turns out, another engineering student (named Ted) asked me to make the app generate horizonal lines on the front and vertical lines on the back so that when you need graph paper, you can actually see it through the paper. It's and old school technique but it's rad. If you want to try it out, just click "Do it up Ted Style"
As the application is written, it wouldn't work well with the folding that you're doing in this instructable - but it's nothing a bit of creative photocopying couldnt take care of rather quickly.
Nice work.


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The FP
Action/Adventure, Comedy
In a dystopian future, a relentless turf war rages. Two rival gangs feud for control of rural wasteland Frazier Park ('The FP') in the deadly arena of competitive dance-fight video game "Beat-Beat Revelation." After hometown hero BTRO is slain on the dance platform by thug leader L Dubba E, his protégé younger brother JTRO (Jason Trost) goes into isolation, vowing never to duel again. One year later, The FP is in ruins, and JTRO must find the courage to return and restore order in a ruthless battle for revenge that can only leave one man dancing.
Cast: Jason Trost, Nick Principe, Lee Valmassy, Caitlyn Folley, Art Hsu
Produced by:
Directed by: Jason Trost, Brandon Trost
Written by: Jason Trost, Brandon Trost
Running time: 1hr 23min
Opens: Mar 16, 2012 Limited
|Theaters for Today
Pick a day
on this day.


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North Dakota Oil Fields Fuel Need for Welders
The job options on graduation day are numerous for graduates of North Dakota State College of Science. Employers from the western oil fields, to manufacturers in Minneapolis to the east, are making offers to the new graduates. Find out what the welding program coordinators are doing to keep up with the demand at its two North Dakota welding labs.
Tags: Dynasty, miller electric, NDSCS, North Dakota, North Dakota State College of Science