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Ohio University BFA Graphic Design Exhibition: Out of Line April 16 – April 22, 2013, Ohio University Art Galley, Seigfred Hall, Athens, Ohio. Out of Line showcased the intellectual,... More > innovative, and dedicated design thinking of the Ohio University Graphic Design graduating class of 2013. These degree projects are intensive investigations completed by the seniors over the course of three months in our final studio class. We were required to realize a self-generated project, motivated by our individual interests and passions. The degree project is the capstone of our research in graphic design at Ohio University.< Less
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Bare Naked Ladies (Men, Too)
By STEPHEN SAWICKI
Published: August 29, 2004
THE figure model Susan Wiebe, 51, has suffered for the sake of art. To hold a pose, she has endured exhaustion, shooting pain and loss of circulation to body parts she never knew could go numb. But when she discovered a tour group of senior citizens peering through the window at the Silvermine School of Art one day as she posed nude for a sketch class, all bets were off.
''I was shocked and kind of upset,'' she said. ''I didn't know what else to do, so I stood up and sarcastically waved at them. And they all waved back.''
A decade has passed since that busload of visitors, on a New England leaf peeping trip, stopped at the arts center in New Canaan to tour the gallery but happened upon a more intriguing display.
''We hadn't gotten curtains yet,'' Ms. Wiebe said. ''But even now, sometimes if there's a little crack, people have to look in. People are curious.''
Technically, modeling is unskilled labor, but people like Ms. Wiebe have long inspired artists, and contributed to countless masterpieces, by finding a good pose and holding it, often stark naked. Across the state, places like Silvermine, the Wooster Art Center in Danbury, Lyme Academy College of Fine Arts in Old Lyme, Yale University School of Art and countless other programs run by community organizations, continuing education groups, high schools and colleges, all depend on models.
''Life drawing has always been a cornerstone in an artist's training,'' said Linda Dente, who runs the artists fellowship program for the Connecticut Commission on the Arts. ''You learn scale, perspective, shading. There's a lot that you learn drawing from a live model.''
The models at Silvermine are independent contractors and are paid $17 an hour, average for the area. Few have health insurance. Models are used for various classes, including figure drawing, portrait painting and sculpture.
The youngest at Silvermine are in their mid-20's; some are in their 70's. Many have other passions, such as their own art, acting or music, and they use modeling to pay the bills. A male model plays piano for a church. Another runs a children's entertainment business. One model even studied to be a nun.
''Some people might look down their noses and say, 'Oh, is that all you do?''' said Betty Pia, 78, an actress who has modeled in an array of costumes at Silvermine for about 50 years. ''But the artists themselves treasure a good model.''
Silvermine School of Art, a part of Silvermine Guild Arts Center, offers adult and children's classes, and has an annual enrollment of 4,000. In the summer, the school uses a dozen figure models. That nearly doubles come autumn, when Silvermine shifts into a full schedule.
Tom Brenner, an instructor, tells of arriving one frigid winter morning to discover a male model asleep in his car. The man had worked the night before at the school and was booked again that morning. Rather than drive home to the Hartford area and back, he simply set up camp.
A longtime model, Tamara Koczanski, used to ride the bus from her home in Stamford to Norwalk. She then walked several miles past stately homes, on roads without sidewalks, to Silvermine. At day's end, with darkness falling, she headed back. These days, a retired neighbor drives her to work.
Silvermine provides too few assignments on which even the top models can survive, so most have multiple clients. They pose for high school and college art classes, community art groups and private artists, the latter of which usually pay slightly better. Some drive to Westchester County for jobs, while others push as far north as Massachusetts and Rhode Island.
Ms. Wiebe, who is single, is an artist. Between working for Silvermine, the Greenwich Arts Council, the Rowayton Arts Center and a sculptor in Stamford, she averages about $250 a week. About $500 a week would be extraordinary, she said, and grueling.
''They struggle and they hustle from place to place,'' said Anne Connell, director of the art school at Silvermine. ''They usually have the most beat-up cars you can ever imagine. They always call me: 'Oh, Anne, I'm broken down. Can you pick me up at the train station?' And I say sure, because we need models.''
Silvermine, like most programs, is always open to new candidates and finds most of its models by word of mouth. Classified ads are seldom worthwhile, Ms. Connell said, as they tend to attract people from the fringes of the pornography industry. When calling, they boast of certain physical attributes that may be appealing for adult entertainment but are of little interest to artists. Sometimes exhibitionists and people who are mentally unstable also respond.
Jak Kovatch, who teaches figure drawing, told of a model from his days as an art student in Los Angeles who believed he was the reincarnation of one of Michelangelo's models. He was dirty, with an unkempt beard and scraggily hair. With Michelangelo's depictions of the crucifixion in mind, the man showed up every day in a robe like Jesus might have worn, lugging a six-foot cross. The students strapped him up on it, then set to work at their easels.

subset: commoncrawl


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Matthew Weiner knew how 'Mad Men' would end for over four years. The image that he held in his mind is the image they shot and used in the final episode, he tells me in our candid video interview. The last season earned 11 Emmy nominations; Jon Hamm could win, finally.Read More »
Plus: The panoramic scope of Robert Altman's "Nashville," and the making of "Who Shot Mr. Burns?"Read More »
The very final scene of "Mad Men" is especially meme-worthy. Watch some of the best parody videos below. (SPOILERS)Read More »
I'm not white, or attractive, or exorbitantly rich, but I *get* Don Draper.Read More »
Look away if you haven't seen the final 'Mad Men' episode. In a recent interview, Jon Hamm reveals his own interpretation of the show's last moments. And it's far less cynical than most.Read More »
For a series with such an intimate understanding of '60s culture, "Mad Men" proved equally aware of the ever-changing modern times.Read More »
"Mad Men" ended the only way it could: with a fitting surprise.Read More »
It could have been longer, but we grouped all the Bobby Drapers together.Read More »
If you think you know what's coming on Sunday, you may have already lost.Read More »


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With an understated hue and just a touch of sparkling adornment, Roberto Cavalli's crepe-jersey dress is a refined take on his signature glamour. Perfectly draped cutout shoulders ensure this fluid piece is anything but ordinary - maximize the sophisticated style with snake-effect sandals and a metallic clutch.
Roberto Cavalli dress: brown crepe-jersey, gathered V-neck, cutout shoulders, three-quarter length dolman sleeves, fitted and gathered cuffs, crystal-embellished gold plaque at bust, fully lined. Concealed zip fastening at side and buttoned keyhole at back. 100% viscose. Designer color: Mahogany.
Product code: 165798 - Need help? Contact us


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Former Victorian Magistrate Simon Cooper avoids jail over sex offences
Cooper was given a three year wholly suspended sentence.
Posted November 20, 2013 10:05:26
Cooper was given a three year wholly suspended sentence.
For information on how you can help, visit abc.net.au/appeals
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AEDT = Australian Eastern Daylight Savings Time which is 11 hours ahead of UTC (Greenwich Mean Time)


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Farm for sale in Valley Settlements A H 3
130 Botterblom, Valley Settlements A H 3
Excellent plot, with a beautiful garden, and a lots of bird sounds. This lovely plot offers you 5 large bedrooms , 3 bathrooms, lounge ...
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text: Toss together, and top pound cake no more than one hour before serving. 0 Read Reviews (0) Yield: Makes about 1 cup Recipe from More from Southern Living Master Three Southern BBQ Sauces 81 Party Appetizers Crazy-Good Fruit Cobbler Recipes 11 Solutions for Common Baking Ingredients Strawberry Pie Recipes Slow Cooker Recipes Recipe Time Prep: 10 Minutes Ingredients Print Recipe Email Save Recipe Add to Menu Add to Shopping List 1/2 cup salted cashews 1/3 cup finely chopped dried apricots 3 tablespoons minced crystallized ginger Preparation Stir together all ingredients. Southern Living October 2007 My Notes Only you will be able to view, print, and edit this note. Add Note 1000 characters remaining Cancel ck-diet


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Bob & Sue
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Bob and I have completely different interests except for computers. Many entries were made when we were new at this hobby. I am adding facts when I can to create more complete Memorial Pages like adding dates and locations when possible from the census with links to other family members. Please do not nag me or hound me with numerous pages of marriage links or maiden names that I listed as middle names. I am getting around to them. If that is all you can find that I did wrong, I did well. We are not the greatest typists. We will fix our errors with a smile.
Our e-mail address: Removed due to many virus attacks with expensive repair fees on a volunteer paycheck.
Refresher of the Find A Grave guidelines:
1) Transfers - We transfer to relatives according to the guidelines. Immediate bloodlines: parents, grandparents, great grandparents and great great grandparents. No transfers - cousins, aunts, uncles, step-children of someone, etc.
2) Photos: Ask before you just take or use. We did the walking and picture taking, not you. Permission will not be granted for any photos we have taken for use on any other website, free or paid. Photos were taken for Find A Grave use.
Contributed facts: "Cut and Paste" with credit going to the contributor. This was much easier to do before the edit tab. Now I just hit ACCEPT and the name of the contributor is gone.
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Christie Stewart
Oscar and Mary Bagwell
Corrections are made, thank you for the update.
Added by
Christie Stewart
on Oct 03, 2015 8:55 AM
Tom Schoening
Donald Edgar Merritt
Thank You for taking the time to process the link to Donald's family - Keep Up the Great Work
Tom Schoening
Added by
Tom Schoening
on Sep 17, 2015 5:30 AM
RE: Robert Rodgers at Evergreen
Finally! Memorial page is updated! Sometimes Find a Grave web site is finicky! Keep the info coming as you find it!
Added by
on Sep 13, 2015 11:59 AM
Robert Rodgers at Evergreen
Tried numerous times & can't memorial page to accept info. This is my 3rd attempt to let you know I am not ignoring and will continue to try to update.
Added by
on Sep 11, 2015 1:03 PM
Barb Walker
Earl Goslin #51153526
You sent me a SAC for this memorial, but were not specific about what the problem is. Can you elaborate, please? Thanks.
Added by
Barb Walker
on Sep 07, 2015 1:04 PM
Linda Jennings
David E Jennings
Thank you for posting my request.
Linda Jennings
Added by
Linda Jennings
on Aug 19, 2015 8:52 AM
George Lieber
Thank you for the prompt update. Peggy
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on Aug 16, 2015 5:00 AM
Alfred and Lola Hugo have been transferred to your care.
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on Aug 03, 2015 1:34 PM
Brian Mooney
interesting find...
So I was researching a postcard as I like to do that I acquired recently, I found that it was from the father in this grave: http://www.findagrave.com/cgi-bin/fg.cgi?page=pv&GRid=52206683&PIpi=28270226 that you posted a photo of... to his daughter, mentioning his mom that didn't live with them at the time, but later did a couple years later.... I'm enjoying researching this... look at the scanned postcard that I attached to the find a grave record... what a find!!!!
Added by
Brian Mooney
on Jul 24, 2015 8:29 PM
Judith W. (Family Finder)
Pearl Lisher Ruckel
Thank you so much for the quick update for Pearl Lisher Ruckel. I greatly appreciate your help.
I'm a Lisher descendant and have been researching this very interesting family for many years. Thanks to you and Find A Grave for helping!
Judith W.
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Judith W. (Family Finder)
on Jul 20, 2015 10:54 AM
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Item of General Interest
August 28. I added three new videos to my Presentations/Podcasts page. These are recordings by staff from the Doomstead Diner on three topics related to TSHTF. There are several people involved, including myself, Nicole Foss, Steve Ludlum and Ugo Bardi.
Tag Archives: per capita wages
The Connection of Depressed Wages to High Oil Prices and Limits to Growth
In my view, wages are the backbone an economy. If workers have difficulty finding a job, or have difficulty earning sufficient wages, the lack of wages will be a problem, not just for the workers, but for governments and businesses. … Continue reading
Posted in Financial Implications Tagged employment, high oil prices, limits to growth, per capita wages, wages 138 Comments


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Medicine and Dentistry courses - there are no vacancies through clearing for our Medicine, Dentistry or Dental Therapy & Hygiene courses. You may like to consider our related courses, including BSc Biomedical Science, BSc (Hons) Healthcare Science (Life Sciences) and BSc (Hons) Healthcare Science (Physiological Sciences). A full list of our vacancies can be found at www.plymouth.ac.uk/clearing.
Plymouth University Peninsula Schools of Medicine and Dentistry (PU PSMD)
Exceptional clinical learning. Strong social engagement. World-class research.
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Email us
Download our prospectus
Come to an open day
Call us
Contact us by email at email@example.com
Call us on +44 1752 437444


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TPE Business
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Compass Club
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TPE has released a video describing why we are enthusiastic about prairies! In the documentary short (27 minutes long), TPE members share their perspectives on learning about, managing and protecting remnant prairies and oak savannas in the midwest.
The 2015 summer/fall field trip flier is available now.
The Summer newsletter is now on-line.
Most of TPE's preserves are open for public hunting for some game species. Details on the properties and the restrictions can be found on the TPE hunting webpage.
Don't forget to start taking photos to enter in the 2016 TPE Annual Photo Contest. The photo above is one of the five finalists from 2014.
Other Conservation and Environment Events/News
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The Spoonflower Handbook is here!
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Man caught burglarizing house
Published: Wednesday, March 13, 2013 at 6:02 p.m.
Last Modified: Wednesday, March 13, 2013 at 6:04 p.m.
Attalla Police on Monday caught a man burglarizing an occupied house, according to a release by Chief Dennis Walker.
Tyrone Woods, 29, Gadsden, was charged Tuesday with second-degree burglary for the break-in on Preston Avenue.
Patrol officers responded to a neighbor's call saying they saw a man walking around the back of the house. When officers went behind the house, they found a broken window. One of the officers went around front and saw Woods exiting the residence.
Woods also had three felony and five misdemeanor warrants at the time of his arrest. He is being held without bond in the Etowah County Detention Center.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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This is a lovely card.
Simple but sweet..
Nice card but background music is soooooo touching.....
Nice card..
Nice E-Cards
Hey ! Thanks to all of you for the wonderful wishes !
Muchas gracias por bendecirnos en esta noche con una comida tan rica, nos la saboriamos y espero...
Thank you all for remembering me on the Bd. Thanks.
These smileys will say thank you just the way you want them.
Say thanks with these cute hug...
Send this nice and cute ecard to say thank you.
A cute teddy with cute gestures says thanks.
Send this cute ecard to say thank you.
Share a note of thanks with someone who has made you feel very special on your birthday.
A warm thank you e-card!
A thank you message for your friends for their wonderful wishes on your birthday.
Send this cute thank you card to anyone who made your day special.
Sweet roses and lilacs and a beautiful butterfly to convey your thanks.
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There is no ballpark per week salary for professional wrestlers since it varies widely. The amount of money professional wrestlers make in a week depends on their popularity, the number of appearances they make and other sources of income from royalties and promotional work.Know More
While some of the most popular professional wrestlers, current and retired, make millions annually, they are in the minority. Wrestlers who are appearing in pay-per-view shows and the like may fall on the high side of average, but according to the Bureau of Labor Statistics, the average salary for athletes and sports competitors was only $40,060 in May 2012. Only 10 percent of those in this industry made more than $187,200.Learn more about Wrestling
Prince Albert was a ring name used by professional wrestler Matt Bloom. The name was used during the first year of his career in the World Wrestling Federation.Full Answer >
Professional Japanese sumo wrestlers weigh 148 kilograms on average. Wrestlers in sumo schools eat two large meals a day consisting of chankonabe, a meat, fish and vegetable stew, rice and beer to help achieve this weight.Full Answer >
According to the U.S. Bureau of Labor Statistics, the median hourly wage for a professional singer was $23.50 in 2012. The term "median" indicates that half of the singers made less than this amount, and half made more.Full Answer >
The Professional Bowler's Association reported earnings for the 2011 to 2012 season ranging from $100 to $140,250. Earnings are based on performance in PBA tournaments, and three bowlers during this period received more than $100,000 for their efforts.Full Answer >


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Apartments Berlin Kreuzberg - Berlin
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- 5 apartments
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- Apartment (Aachener Str.)
- Apartment, 2 Bedrooms (Schleiermacherstrasse)
- Apartment (Berlin Mitte)
- Apartment (Aachener Str. 39)
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- This hotel has 5 rooms
- Check-in time 2 PM-8 PM
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- Minimum check-in age is 18
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- No parking
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- Resort fee included
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- 5 percent tourism fee will be charged
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APW Wyott 32010635 30 5/8" x 7 1/2" Poly Cutting Board for 2 Well Sealed Element Steam Table
- For use with APW Wyott sealed element 2 well steam tables
- Durable design
- 7 1/2'' deep work surface
- Perfect for small-scale food preparation
- Includes necessary mounting hardware
This APW Wyott 32010635 poly cutting board is designed specifically for use with your sealed element 2 well steam table. With a 7 1/2" deep work surface, this poly cutting board is perfect for small scale food preparation.
Overall Dimensions:
Width: 30 5/8"
Depth: 7 1/2"
Height: 1/2"
Because this item is not stocked in our warehouse, processing and transit times will vary. If you need your items by a certain date,
please contact us prior to placing your order. Expedited shipping availability may vary. We cannot guarantee that this item can be cancelled off of the order once it is placed.
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All APW Wyott cooking equipment is backed by a 1-year limited warranty and a 1-year on-site labor warranty. RESIDENTIAL USERS: APW Wyott assumes no liability for parts or labor coverage for component failure or other damages resulting from installation in non-commercial or residential applications.
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"You cannot always score on the PP," Ribeiro said. "I think they pressed well up the ice. But I think we got good chances to score. We had a good, few shots there that we didn't connect. … You just need to battle through. Obviously when you're first, you're expected to score every game."
That's exactly why Oates said last month he'd almost rather not have the league's top power play. There's too much expectation involved.
"You're focused on it too much," Oates said. "I don't want the guys driving to the rink thinking, 'Oh, I can't wait for my three power plays tonight,' because there's still 54 minutes besides that that you need to think about."
The Caps managed to score twice at even strength, but now they have a lot of minutes to think about a missed opportunity to pick up a couple of valuable points.
Going on the road for three games after Tuesday's defeat, players at least have the confidence to draw from a 3-1 trip last week that put them into playoff contention.
"We're still in the fight," Laich said. "[We'll] hit the road [with] the same mentality that we did last week."


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Originally posted on Fox Sports Houston | Last updated 10/29/11
COLLEGE STATION -- The Missouri contingent of supporters conducted themselves with the utmost decorum while tucked into the southeast corner of Kyle Field on Saturday, cheering modestly as the Tigers defeated No. 16 Texas A&M 38-31 in overtime offering a preview of what might one day be an interdivisional SEC battle. They were more reserved than rollicking, erupting only after Missouri nose guard Dominique Hamilton deflected a Ryan Tannehill pass intended for Aggies receiver Ryan Swope on fourth down in overtime. Five weeks earlier, the Aggies were subjected to the derisive cheers of Oklahoma State fans after the Cowboys fashioned an improbable second-half rally here, serenading their conference rivals with mocking "Big 12" chants as the Aggies dejectedly trudged off the field on Sept. 24. Missouri left well enough alone, opting not to poke Texas A&M with the same dismissive stick. The Tigers understand that had the Aggies not bolted through the door of conference reali...
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365-Day Returns... Hassle-Free!
HOME New York Rangers Gear New York Rangers Ladies New York Rangers Ladies T-Shirts New York Rangers Ladies T-Shirts Tank Tops (8 items) Product ID: 1322819
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Shop early for holidays and birthdays with our 365 Day No-Hassle Return Policy! Because we stand behind the quality of our products, you can return any item in original condition for up to a full year from the purchase date. We want you and your gift recipients to love what you ordered, but if not, we make returns easy for you.
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Never Mix Magic YKTTW Discussion
|Never Mix Magic
Combining two different types of magic is bad.
In a world of Functional Magic, there are many different types of magic and phlebotinum, each with its own complex set of rules and laws. And they each work pretty well as long as each one is kept separate. However, mixing magics is almost always disastrous. The two magics tend to interact in fairly unexpected ways, sometimes appearing far bigger or smaller than expected and sometimes creating an entirely new magic altogether. Needs More Examples, Needs a Better Description
- In the Aladdin animated series, Genie often used this as the reason he couldn't simply poof away someone else's spells or magic.
Replies: 17


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Friends of Morningside ParkShared publicly -
Free Concert! Performers: Rita Dottor, 4pm, Evan Coles, 4:30pm, The Tevin Thomas Group 5pm, Doutnee Roze 5:30pm, Jutaun 6pm and Kwame Binéa 7pm - 8:30pm.
Summer Solstice Concert - Bring your own picnic
Sat, June 21, 2014, 4:00 PM
West 114th Street and Morningside Ave, New York, NY
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Your massage will begin with a short consultation and assessment of your needs and expectations from one of our experienced practitioners.
Our House Signature massage, combining cold pressed base oils with a unique blend of essential oils, including Lavender, Frankincense and Sandalwood in Organic Sweet Almond and Jojoba. A full body 60 minute massage will apply this combination of oils to nourish the skin and allow your mind to relax and escape from the humdrum of life, with the evocative aromas of Lavender fields and Woody undertones of Sandalwood, with the sweet resin like scent of Frankincense. Tranquility!
Please note this is our signature Swedish massage therapy only.
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Transform any surface into a changing station for your baby with the Colgate Contour changing pad. Constructed from lightweight firm foam, this convenient changing pad features a unique contoured design, with two ridges on either side, to keep baby safely in place during diaper changes. Covered in wetproof quilted white fabric, this hypoallergenic changing pad also includes safety straps and installation screws to keep even the wiggliest of little ones secure.
Changing Pad
|33L x 16W x 4H


text: The Brian Lehrer Show Edit this Published in The Brian Lehrer Show Deradicalize Listen 11 min Queue Download this audio Want to embed this player? Use the code below. More info. <iframe frameborder="0" scrolling="no" height="130" width="100%" src="https://www.wnyc.org/widgets/ondemand_player/wnyc/#file=/audio/json/29674/&share=1"></iframe> Share on Facebook Share on Twitter Email a Friend Karen Greenberg, executive director of the Center on Law and Security at NYU Law School, talks about efforts to deradicalize terrorists in the context of the prospect of closing Guantanamo.


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The Latest Scoop - July edition
Expand Messages
- A regularly-updated column with the latest information on textbooks
and their revisions gleaned from the publishers. It is compiled by
Deb, the religion product specialist from Communication Center, a full-
service distributor of textbooks and Bibles to Catholic churches and
schools around the country.
URL: http://www.silk.net/RelEd/scoop.htm
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Business Certificates
Certificate degrees in business are typically shorter than associate and bachelor degrees. More often than not, you can finish a certificate program between one to 12 months. Furthermore, the topics or subjects you can specialize on include applied management, advertising, basic accounting, business administration, financial management and human resources management. Majority of working individuals that get certificate programs in business are interested in gaining skills and knowledge on information technology. New certificate programs in e-business or e-commerce, technical writing, and non-profit management are now available.
Since many people who decide to take certificate degrees in business do not have ample money or financial support to pursue bachelor degrees, it is important for them to get a job as soon as they finish their short business course. Fortunately, the demand for entry-level positions in business continues to be strong. You can surely find work as administrative assistant, office clerk, word processing clerk, retail store specialist, or sales associate easily. Although many companies take a closer look at the educational background of candidates seeking supervisory or managerial positions, there are still instances when long years of experience and a certificate course can make one eligible for higher positions.
According to an Internet-based salary research company, an entry level office clerk with no experience can earn between $8 and $11 per hour. Aside from years of experience, the salary of office clerks and similar positions also depend on geographical location.
Business Schools
Liberty University
With more than 300 online and residential areas of study, Liberty offers programs from the certificate to doctoral level.
- CERT: Business Administration
Baker College Online
- Associate of Business - General Business
- Associate of Business - Marketing
- Associate of Business - Accounting/Management
ITT Technical Institute
- AS - Business Management
Location: Online
Charter College Online
You can advance your career with a degree from Charter College Online.
- Certificate - Business Office Administration
- AS - Business Administration
Location: Online


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'Pontet', in all its Glory, 1 acre of garden.
Outside bar area , including mini fridge , BBQ , dining table for 6 , parasol.
Openplan living , flatscreen TV , English freeview
bedroom 1 , flat screen tv , english freeview , dvd and selection of films.
Dining Area , french doors directly onto terrace. Music system.
Salon , large selection of books and dvds.
Kitchen. Extremely well equipped.
Kitchen , breakfast bar.
Bedroom 2 , tv and dvd.
Downstairs Shower Room
Downstairs Shower Room
Master Bedroom Large TV and DVD.
Master Suite
Master en suite bathroom
Lunch at the pool
Medieval Festival
Dream holiday
Pool area with 6 sun loungers , cushions and 2 parasols
farniente, pergola and hammock area for total relaxation.
Enter a caption for your photo


text: Favorite deal Favorited! Get email updates for this deal? NO YES Members Only Men's Moto Jacket $31 at Target retail: $75 $31 Target has the Members Only Men's Moto Jacket for $26 + $5 shipping = $31 shipped. Normally $75. This blast from the past is available in sizes M to XXL. CREATE ALERT Deal has expired EXPIRED Posted 866 days ago by Ouragos Report Report this deal Report an Error Close Members Only Men's Moto Jacket $31 at Target Deals can expire unexpectedly at any time. Problem: Out of Stock Deal Expired Other Error (please explain) Comments: (Optional) Submit


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There comes a time in every Schwarzenegger boy's life when he brings home the girl he's fucking to remind dad that he's not gay, that's the other son who sides with mom. Arnold was exceedingly gracious and even wore his less obvious weave to meet Miley Cyrus and his son Patrick for breakfast in Ketchum, Idaho. As per Schwarzenegger custom, dad plunged two fingers into Miley's vagina to determine her compatibility with his son. It's like eHarmony, but with much less intrusive questions. Arnold tasted his moistened digits and pronounced the relationship sound. Wunderbar. Everybody had toast and pretended Maria would ever accept this.
Photo Credit: Archives


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Data science is about extracting knowledge from data to optimize processes, reduce risks, or improve user experience. RaaS enables data scientists to provide businesses with results.
Push your success ahead: For example with eoda´s R-Academy
Potential and possibilities of the free statistics language R for new business models in the era of industry 4.0
translate your SPSS® Code to R automatically. Request a demo.
Use the potential of Big Data for your industry. Our customized solutions will support you.
We advise you individually and target-oriented on important topics related to statistical data analysis – technological and methodological. Benefit from our know-how.
We develop high-quality software solutions for your needs based on established products of our partners or individually customized for your use case – for example with our service platform "Results as a Service" or the statistics software R.
From data management to the right analysis methods to the visualization of the results – in our R Academy you will learn how to turn data into knowledge.
A high-performance product portfolio around our service platform "Results as a Service". With Results as a Service we connect data science with your business requirements and unlock the potential of big data for you. Our solutions stand for intuitive handling, high flexibility, fast deployment and valuable results.
Targeted and innovative solutions for your individual needs related to data mining and predictive analytics
Differences between SPSS and R and the idea behind translate2R.
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The first holistic R Event in the German-speaking community.
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The Visualization of spatial data is one of the most popular applications when using R.
The R Academy of eoda is a modular course program for the R statistical language with regular events and training sessions. The course concept is aimed to train you to become an R expert.
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Understanding Clinical Use
- Jawahar Mehta, MD, PhD, Stebbins Chair in Cardiology, Professor of Internal Medicine, Physiology and Biophysics, Director, Division of Cardiovascular Medicine University of Arkansas Medical School, Little Rock, AR
STATINS: Understanding Clinical Use was written with you—the busy practitioner—in mind. It covers the class of drugs as a whole, discusses the benefits of statin use, and offers future perspectives on ancillary drug actions beyond cholesterol lowering. Leading expert Jawahar Mehta, MD offers you top-notch guidance based on his research and extensive clinical experience—all in one compact source so you don't have to wade through piles of literature to find the information you want.View full description
Cardiology, Cardiology Fellows in training and Residents, Internal Medicine, Pharmacology
Book information
- Published: March 2004
- Imprint: SAUNDERS
Table of Contents1. Statins- The discovery
2. Efficacy of statins in atherosclerosis- animal studies
3. Efficacy of statins in atherosclerosis- human studies
4. Statins and Coronary heart disease
5. Statins and stroke
6. Platelet inhibitory and anti-thrombotic effects of statins
7. Statins, nitric oxide and endothelial function
8. Statins as anti-oxidants
9. Different aspects of modulation of inflammation by statins
10. Different aspects of modulation of inflammation by statins
11. Different aspects of modulation of inflammation by statins
12. Different aspects of modulation of inflammation by statins
13. Bone preservation by statins
14. Statins and cancer
15. Statins and neo-vascularization


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Tiny Architecture: 5 Modern Outbuildings
Who doesn't fantasize about a small place of one's own—a retreat, an escape, a house built for one? Here, five small modern outbuildings that don't skimp on design—and offer a chance to be alone,...07.02.13
5 Perfect Planters for Your Garden
Generate some of your own shade this summer with lush plants and their equally attractive planters.07.10.13
5 Great Lakeside Homes Around the World
A cool breeze coming off the water is the best escape from a mid-summer heatwave. These five lakeside homes combine modern design with fresh locations to serve as the perfect summer retreats.written by: Emma Marsano07.11.13
6 Outdoor Patio Dining Essentials
Summer brings warm nights and the perfect atmosphere for outdoor patio dining. Set the stage for an evening on the terrace with these six patio dining essentials from shatter-proof wine glasses to...07.12.13
Charming Weekend Cottage Renovation in Marin
A Bay Area landscape designer works her yard like a jigsaw puzzle, packing a bevy of distinctive destinations into a steep and diminutive plot.photos by: Morgan Rachel Levy07.23.13
6 Relaxing Porches, Patios, and Terraces
You've had a long day. Take a moment to daydream and picture yourself relaxing on any one of these beautiful porches, patios, and terraces from farmhouses to island getaways. You're welcome.07.31.13
3 Options for Outdoor Lighting
As summer nights swing into high gear, this outdoor lighting will keep your evenings bright.08.02.13
3 Modern Birdhouses to Beautify Your Yard
Your home is modern. Why not offer similarly stylish digs for your winged neighbors? Here, three modern birdhouses to enhance any yard.08.05.13
5 Modern Saunas
A stint in a sauna rumored to have myriad benefits from the social and heath standpoints and if you've considered building one of your own, here are five examples from the Dwell archive. For more...written by: Diana Budds08.08.13
6 Modern Soaking Tubs
From a rustic, 19th-century trough clad in stainless steel to a couple's Zen bath fronted by smooth pebbles, here are 6 modern soaking tubs designed to inspire you to find creative ways to pamper...08.09.13
6 Indoor-Outdoor Hammocks
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5 Modern Edible Gardens
Urban gardens are cropping up everywhere, from the country to the city. To follow are five modern ways to grow your own.08.16.13
Barbara Bestor's Colorful Modern Home in Silver Lake
We first documented the ten-month renovation of Los Angeles-based architect Barbara Bestor's 1950s bungalow here, but gather your things and get ready to soak in some sun rays yet again by visiting...written by: Eujin Rheephotos by: Dabito08.22.13
Dwell's Coolest Modern Backyards
Dwell spotlights the coolest modern backyards from the pages of our magazine.08.26.13
7 Tiny Backyard Retreats
From a nature writer's off-the-grid Puget Sound getaway to a Texan's shipping container guesthouse, these retreats may inspire you to make that backyard retreat you've been dreaming of a reality.08.27.13
Fresh Eggs: 5 Modern Chicken Coops
Talk about farm-to-table. Having your own chickens means the freshest of eggs and no further than your own backyard. Of course, you'll need a place to house your hens. Take a look at these five...08.29.13
6 Rooftop Hangouts
With forethought and engineering, a rooftop can be a very valuable bit of real estate. Here are six cool roofs that not only work overhead, but underfoot.08.29.13
5 Creative Modern Porches and Decks
As these five projects prove, a modern deck or porch can play many creative roles—as a play space, hangout spot, dining area, and more.09.07.13
5 Public Landscapes of Isamu Noguchi
With a body of work spanning sculpture, dance, furniture, lightning, and landscapes, Isamu Noguchi is one of the most revered figures in the 20th-century canon. Buckminster Fuller once called...written by: Diana Budds09.20.13
5 Modern Courtyards Part Two
As Previously looked at in 5 Cool Modern Courtyards, Dwell takes another glance at 5 modern homes with outstanding elevated terraces.written by: Jami Smith10.08.13
7 Great Green Walls
Not for the feint of heart, but for the green of thumb: A living wall is a vibrant way to celebrate nature in tandem with architecture. Peek through our archives for another look at living walls...written by: Kelsey Keith10.10.13
Slat Happy: 8 Louvered Homes
Dwell's aesthetic has been summed up by a few aesthetic traits: flat roofs, glass walls, and wood slats. While that isn't always the case, we do appreciate louvered facades for how they help...written by: Kelsey Keith10.11.13
A Two-Part Landscaping Renovation in San Francisco
In an unusual collaboration among birds, wind, and one of San Francisco's leading landscape architects, a California designer has made a pair of unique outdoor living spaces—one low and one high.written by: Zahid Sardarphotos by: Ike Edeani10.15.13
7 Modern Outdoor Fireplaces We Love
There's no better time to gather around an outdoor fire pit then on a windy Autumn night. Check out these cozy outdoor areas, equipped with the latest technology and embracing timeless traditions...written by: Dwell Staff10.17.13
Primer on Landscape Architecture
Don't know your Lawrence Halprin from your Richard Haag? We've rounded up some of our favorite articles, interviews, and essays on modern landscape architecture.11.04.13


text:
Belize is a much sought after holiday destination because it offers a variety of experiences that, when combined, allow you to get to know Belize as the culturally unique and diverse destination it is. From beach relaxation to jungle adventure, enjoy the best of everything with our all inclusive in Belize vacation package.
Accommodations, Meals, Tours & Transfers
- 5 or 7 Nights in Accommodations of your choice
- Roundtrip air transfers from Belize's International Airport to Dangriga's airstrip
- Roundtrip land transfers from Dangriga's airstrip to Hopkins Bay
- Daily breakfast, full or packed lunch and dinner at the Rhum Shack
- Unlimited local alcoholic and non-alcoholic beverages
- 1 Full-day Monkey River Tour with a stop in Placencia
- 1 Half-day of Snorkeling at Southwater Caye
- 1 Village Bicycle Immersion Tour
- 1 Kayak Safari Nature Tour
- 1 60-minute Swedish Massage
- Complimentary Welcome Cocktail, parking and WiFi, use of bicycles and kayaks
Per Person Rates
*Rates are in US Dollars and do not include an additional cumulative 8% Gratuity and 12.5% Sales Tax.


text:
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Can you believe in God and evolution? Yes, if you keep the two separated in logic-tight compartments.
Belief in God depends on religious faith. Belief in evolution depends on empirical evidence. This is the fundamental difference between religion and science.
If you attempt to reconcile religion and science on questions about nature and the universe, and if you push the science to its logical conclusion, you will end up naturalizing the deity because for any question about nature — the origins of the universe, life, cells, humans, whatever — if your answer is "God did it," a scientist will ask, "How did God do it?, What forces did God use? What forms of matter and energy were employed in the process?" and so forth. The end result of this inquiry can only be natural explanations for all natural phenomena. What place, then, for God?
If God is nothing more than the laws of nature themselves, then this is pantheism and not the type of God to which most people profess belief. A God who is outside of nature — super nature, or supernatural — is by definition outside of science and evolution, and thus the two are irreconcilable.
Enter intelligent design (ID), which argues that life is too specifically complex (complex structures with specific functions, like DNA) and irreducibly complex (reduce a complex structure by one part and it loses its function, like eyes) to have evolved by natural forces. Therefore, life must have been created by a supernatural force — an intelligent designer.
In these pages this week, Rabbi Reuven Bulka asserted that "I have no problem with evolutionary ingredients in creation. This can co-exist quite comfortably with intelligent design, or God's design, which is stretched out on an evolutionary canvas" ("We must fight to keep life sacred" — July 7). The problem is that intelligent design theory is not science. The proof is in the pudding.
Intelligent design theory lacks, for instance, a hypothesis of the mechanics of the design, something akin to natural selection in evolution. Natural selection can and has been observed and tested, and Charles Darwin's theory has been refined. But ID has no corresponding mechanism, other than "God did it," which is a religious statement, not a scientific hypothesis.
Intelligent-design theorists admit the difference, at least among themselves. Here is ID proponent Paul Nelson, in Touchstone, a Christian magazine: "Right now, we've got a bag of powerful intuitions, and a handful of notions such as 'irreducible complexity' and 'specified complexity' — but, as yet, no general theory of biological design."
The term "intelligent design" is nothing more than a linguistic place-filler for something unexplained by science. It is saying, in essence, that if there is no natural explanation for X, then the explanation must be a supernatural one. Proponents of intelligent design cannot imagine, for example, how the bacterial flagellum (such as the little tail that propels sperm cells) could have evolved; ergo, they conclude, it was intelligently designed. But saying "intelligent design did it" does not explain anything. As with the above set of questions about God's providence, scientists would want to know how and when ID did it, and what forces ID used. In fact, invoking intelligent design as God's place-filler can only result in the naturalization of the deity. God becomes just another part of the natural world, and thereby loses the transcendent mystery and divinity that define the boundary between religion and science.
The problem with all of these attempts at blending science and religion may be found in a single principle: A is A. Or: Reality is real. To attempt to use nature to prove the supernatural is a violation of A is A. It is an attempt to make reality unreal. A cannot also be non-A. Nature cannot also be non-Nature. Naturalism cannot also be supernaturalism.
Believers can have both religion and science as long as there is no attempt to make A non-A, to make reality unreal, to turn naturalism into supernaturalism. The Separate-Worlds Model in which science and religion deal with completely different subjects is the only way to do this. Thus, the most logically coherent argument for theists is that God is outside of time and space; that is, God is beyond nature — super nature, or supernatural — and therefore cannot be explained by natural causes. This places the God question outside the realm of science.
If there is a God, the avenue to Him is not through science and reason, but through faith and revelation. If there is a God, He will be so wholly Other that no science can reach Him, especially not the science that calls itself intelligent design.
Michael Shermer is an adjunct professor in the School of Politics and Economics at Claremont Graduate University, the publisher of Skeptic magazine, and a monthly columnist for Scientific American. He is the author of Why Darwin Matters. His latest book is The Mind of the Market.


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OC3D Reviews ›› Memory
Corsair XMS3 DHX PC3-12800 (DDR3-1600) 4GB Kit
Memory | 26th June 2008
Fancy a 4GB DDR3 kit capable of running at 2000mhz? Corsair's affectionately named TW3X4G1600C9DHXNV kit may just well be what you're after.
Crucial Ballistix PC3-16000 (DDR3-2000) 2GB Kit
Memory | 22nd May 2008
With a stock speed of DDR3-2000 Crucial have one extremely fast DDR3 kit on their hands. But will it overclock any further? We find out.
Corsair XMS2 DHX PC2-6400 4GB Kit
Memory | 17th April 2008
A further addition to the DDR2 market, the XMS2 DHX kit steps up to try push the tech that little bit further.
OC3D Articles ›› Memory
Kingston HyperX Black
Jonathan Stones | 27th April 2013
We take a quick look at the 'black' variant of Kingston's HyperX Blu memory module.
AMD Branch out into Memory
Ian Mulcrone | 25th January 2012
It seems AMD, like every other company at the moment, want to Diversify into a new market...
Kingston Updates Lineup
Ian Mulcrone | 10th January 2012
Kingston Technology Adds HyperX Red, Refreshes LoVo
Corsair Announces White Vengeance LP DDR3 Memory
Mark Lewis | 4th August 2011
Special Arctic White Edition Vengeance LP DDR3 Memory is due shortly...
Aeneon Xtune PC3-10600 (DDR3-1333) 2GB Kit
Memory | 27th February 2008
A new kid in the DDR3 market shows us what it's made of.
Cellshock PC3-14400 (DDR3-1800) 2GB DDR3 Kit
Memory | 16th February 2008
Having been impessed with several of Cellshock's DDR2 based kits, it's finally time to put their latest DDR3 kit through its paces.
Crucial Ballistix PC3-12800 2GB DDR3 Kit
Memory | 24th January 2008
Crucial Ballistix DDR2 kits have always been a favourite among overclockers. Today we'll be reviewing the DDR3 incarnation to see if they are worthy of the Ballistix name.
OCZ ReaperX PC2-6400 4Gb DDR2 Kit
Memory | 16th January 2008
Just when we thought that all the DDR2 reviews had dried up, OCZ comes and surprises us with their latest "ReaperX" 4GB kit.
Patriot PVS32G1866LLK Viper Series PC3-15000 2GB
Memory | 30th December 2007
Just 3 weeks ago we tested Patriot's non-Viper PC3-15000 kit, However since then Patriot have made some changes and we've been invited to take a 2nd look
Corsair Announces Limited Edition 1.5V 8GB Dominator GT Kit
Mark Lewis | 19th July 2011
New 8GB (2x4GB) kit boasts the most aggressive timing specification in its class!
G.Skill Launch new 'Sniper' memory series
Alex Myers | 15th March 2011
These new low voltage DDR3 kits have their own unique style, clearly aimed at gamers and case modders.
G.Skill Unleashes RipJawsX Memory Kits for Sandy Bridge
Gaurang Shah | 8th February 2011
High performance memory maker G.Skill today announced the unveiling of its all new RipJawsX series memory modules for Intel's Sandy Bridge LGA 1155 processors.
G.Skill Shows off RipjawsX Memory Kits for Sandy Bridge
Gaurang Shah | 3rd January 2011
Leading memory manufacturer G.Skill today joined the race with the launch of its RipjawsX series memory modules.
Patriot Announces Viper Xtreme Memory Modules for Sandy Bridge
Gaurang Shah | 28th December 2010
Leading memory manufacturer Patriot Memory has updated its Viper Xtreme series of memory modules to match Sandy Bridge specifications.
Corsair Intros 4GB Low Voltage Dominator GT DIMMs
Gaurang Shah | 14th December 2010
Corsair today announced the launch of their new low voltage memory kit in the form of the 4GB Dominator GT DIMMs.


text:
Bike maker Scott has revamped its high-end suspension bikes for 2013, with a new range of Genius 150mm travel rigs with 29er wheels and with the intermediate 650B/27.5in wheel size. The company's acquisition of the Syncros brand name back in January is also bearing fruit with a range of parts and accessories.
The UK arm of bike maker Scott Sports spent last week travelling the country showing off its 2013 range to dealers. Bikemagic caught up with the good folks from Scott at the High Wycombe show to get an insight into the range highlights.With 150mm of rear travel, the Genius 7XX series bike have 650B/27.5in wheels. The five-model range implies Scott thinks the intermediate wheel size has legs.
Scott's big news is the Genius 7XX range of 150mm suspension bikes. The range comprises five bikes with 650B/27.5in wheels, three in carbon fiber and two in aluminium, and Scott claims the top carbon bike, the Genius 700, has the lightest 150mm travel frame available. There are also 29er versions of all five bikes, with 130mm of travel.
Incidentally, Scott has a new model naming convention. The numbers indicate wheel size (9XX for 29ers, 7XX for 27.5in/650B and 6XX for 26-inch wheels) and position in the range from X00 at the top. The Genius 700 SL is the top model 27.5/650B Genius, then, while the Scale 970 and Scale 670 are the value end of the race hardtail range, in 29er and 26-inch respectively.
The new Geniuses use the linkage and push-shock design Scott introduced on the Spark, abandoning the pull-shocks of old. Scott says the Dual Air Spring shock is more tunable than the old Equalizer2 shock, and its position in the frame means it's better protected from flying crud.
Like many manufacturers Scott has run into the limitations of wheel travel on 29ers and has settled on 650B/27.5in as the solution. There are both 29er and 650B/27.5in versions of the Genius, with 130mm and 150mm of travel respectively. (The 185mm travel Genius LT remains a 26er.)The latest version of Scott's Twinloc lever is longer to make it easier to use.
Scott has an extensive explanation of the thinking behind the size choice on its website, but it boils down to keeping the ride and handling characteristics right. To make a 150mm travel bike with 29-inch wheels would require a longer wheelbase and other design compromises that Scott wanted to avoid.
There's a lot more to the new Genius models than just wheel sizes though. Scott has improved its three-position suspension travel technology, which gives you a lock-out option and two different amounts of travel for riding and descending. Not only can fork and shock be adjusted from the same switch, but there are different damper settings in the Nude2 rear shock for each of the two travel lengths.
All the pivots have been made larger compared to the Genius' previous bearings and the linkage is a single piece for improved rigidity.
The front subframe is moulded in one piece in Scott's IMP process and all the details are thoroughly modern: BB92 bottom bracket shell, internal cabling, Chainblocker plate and ISCG mounts, interchangeable drop-outs and post mount brakes on the chainstays.
Like a lot of Scott's bikes for 2013, the Geniuses use predominantly Shimano component sets. Phil Stevenson says Scott were not happy with other suppliers' brakes, so went with Shimano for stopping performance.
If all this talk of a new wheel size gives you a headache, scroll down to the bottom of the page for a bit of – we hope – useful explanation of what's going on.
Gear and clothes: Syncros flies again & moreThe Syncros parts range includes some very light saddles, like the carbon-railed TR1.0 here at a claimed 170g.
In January of this year, Scott bought the Syncros brand name from Ritchey, who owned it since 2003 after it underwent a tortuous journey from its Canadian roots thorough various hands.
Scott's 2013 bikes use plenty of Syncros-branded components, including wheels, bars, stems and seaposts. It looks very much as though Syncros will become to Scott what Bontrager is to Trek, a good-quality house brand for components and accessories. Welcome back.Scott won an award at Eurobike for the AMT jersey and the matching shorts.
Scott won an award at the Eurobike show for AMT jersey and shorts, which are super-lightweight and easy to pack. There's also a matching light jacket that weighs a claimed 60g.Scott's new Lin and Taal helmets (this is the Taal) feature MIPS, a cradle design that heklps absorb angled impacts.
Anyone who's ever fallen off a bike knows you rarely land directly on your head in the way simulated by helmet standard tests. Rolling and rotational impacts can do severe damage to your brain, according to the inventors of a helmet design called Multi-directional Impact Protection System (MIPS) that Scott has adopted for two of its helmet models.
In a MIPS helmet, the internal cradle grips your head, but the outer shell can move slightly to absorb rotational impacts. You'll find it on Scott's lin and taal helmet models.Scott's new Leap eyewear have wide, curved lenses for an uninterrupted view.
For the space between your helmet and your nose, Scott has some new cycling eyewear in the form of the Leap wrap-arounds. They're available in various dark-lens options, with clear lenses for dark conditions and with photochromic lenses for those days the weather can't make up its mind.
Open Gallery21 Images
650B/27.5inch wheels & tyres: what you need to know
There are now three mountain bike wheel and tyre sizes duking it out. Reports of the death of the venerable 26-inch wheel are probably premature, but the wheel size we've known since the 70s is definitely under threat.
The danger man is the 29-inch size that's become popular over the last few years. This uses the same rim size as road bikes, known as 700C or, if you like techie designations, ISO 622mm.
That number is the size of the rim where the tyre sits. Add a 50mm tall tyre and you get a wheel 722mm across in total. There are 25.4 millimetres to the inch so that's about 28.5 inches in old money, though everyone rounds it up to 29.
A 26-inch mountain bike tyre is ISO 559mm. Add our 50mm tyres and we get 659mm which is almost exactly 26 inches.
Some designers think that 29-inch wheels are just too big, especially for smaller riders and longer-travel bikes. They've picked up an old French wheel size – 650B – as a happy medium.
A 650B wheel is ISO 584mm, so actually yields a wheel and tyre combo 27 inches across. However, we're seeing plenty of fatter tyres on these bikes, so they do end up about 27.5 inches.
The claim is that 650B/27.5in gets you some of the faster-rolling advantage of a 29-inch wheel without as much of the extra weight. If you're a designer trying to make a long-travel bike it also means you can achieve that without the bars ending up too high, or the wheelbase too long.
Nobody seems to be 100 percent sure what to call these wheels and tyres. The French designation 650B doesn't mean much to anyone but tyre nerds, but "twenty-seven point five inches" doesn't trip off the tongue so much as fall on its face and break its nose. One German manufacturer we were talking to recently pointed out that "sechshundert fünfzig beh" was clunky too.
We're therefore hedging our bets and going with 650B/27.5in.
The Bikemagic crystal ball looks pretty murky when we try and predict the future of wheel sizes, but if you force us to make a prediction, we'd say 650B/27.5in is going to carve a niche in longer-travel bikes, and 29-inch is going to dominate hardtails and shorter-travel rigs.


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... that had large homes with big porches. The owners were great, and quckly showed me to a completely finished basement that had a large tv room; office; full bath and large bedroom. I had this all to myself for $62.00. The only downside was the fact that their wifi was not working. The father and son tried for an hour to figure it out. I told them to throw in the towel, as I was ready to crash at 8 pm.
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The Road Less Traveled
As we crawled into the tent last night we got our first real taste of sleeping in a tent in the desert...even with the rain fly staked down the wind blew sand into the tent, all over the sleeping bag. We're not just talking about a little sand either; the entire sleeping bag was covered! Thankfully, it was closed, so the sand wasn't in the sleeping bag, but it was still not pleasant. Just one more reason we are thinking of getting a ...
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... was really cool because it was something we had never done, but after a while we got too cold and had to go home. We drove back home and Donovan and Kinsey built Legos while I did some coloring. Then we had a really nice Christmas dinner, we had a brisket with cranberry sauce. Then we had a really super nice chocolate log roll for desert and went to ...
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text: Entrepreneurs Video: Creator of Second Life unveils latest project Add to ... Reuters Published Monday, Aug. 27, 2012 9:54AM EDT Last updated Monday, Aug. 27, 2012 1:23PM EDT After creating the virtual world Second Life, serial entrepreneur Philip Rosedale is now looking to create tools to help the entrepreneurs of tomorrow in the real world Watch More Video: Dell buys EMC for $67-billion Watch as MIT researchers test their 3D-printed hand How washing the dishes also helps you wash away stress A backpack that can save your life So does the new iPhone 6s live up to all the advance hype? IPO market for Canadian tech to heat up in two years: venture fund Does stronger glass always mean fewer smashed smartphones? Kim Dotcom extradition hearing resumes Fake iPhone 6s on sale in China Scientists use brainwaves to help disabled gain mobility A colon just floating in the air: Doctors use 3-D projections to help with procedures Some Skype users can't make calls Apple on alert for Chinese malware in apps It's back to work for the Duchess of Cambridge Is it really cheaper to live in the suburbs? New device looks to zap away motion sickness Finnish post office tests using drones to get mail to an island Are robotic lawn mowers worth the investment? Deutsche to cull 23,000 jobs How wearable technology went from fad to fashionable Comments AA More Related to this Story Environment Video: Oysters used to clean New York's waterways Technology Video: Patent verdict sparks selloff of Samsung shares, but will it last? Technology Video: Samsung and Apple both to blame, says S. Korea judge


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High level expression and purification of antimicrobial human cathelicidin LL-37 in Escherichia coli
ABSTRACT The human antimicrobial peptide LL-37 is a cationic peptide with antimicrobial activity against both Gram-positive and Gram-negative microorganisms. This work describes the development of an expression system based on Escherichia coli capable of high production of the recombinant LL-37. The fusion protein Trx-LL-37 was expressed under control of T7 promoter. The expression of T7 polymerase in the E. coli strain constructed in this work was controlled by regulation mechanisms of the arabinose promoter. The expression plasmid was stabilized by the presence of parB locus which ensured higher homology of the culture during cultivation without antibiotic selection pressure. This system was capable of producing up to 1 g of fusion protein per 1 l of culture. The subsequent semipreparative HPLC allowed us to isolate 40 mg of pure LL-37. LL-37 showed high antimicrobial activity against both Gram-negative and Gram-positive microorganisms. Its activity against Candida albicans was practically nonexistent. Minimal Inhibition Concentration (MIC) determined for E. coli was 1.65 microM; for Staphylococcus aureus 2.31 microM, and for Enterococcus faecalis 5.54 microM. The effects of cathelicidin on E. coli included the ability to permeabilize both cell membranes, as could be observed by the increase of beta-galactosidase activity in extracellular space in time. Physiological changes were studied by scanning electron microscopy; Gram-positive microorganisms did not show any visible changes in cell shapes while the changes observed on E. coli cells were evident. The results of this work show that the herein designed expression system is capable of producing adequate quantities of active human antimicrobial peptide LL-37.
- SourceAvailable from: Stanislav Stuchlík
- "To explore the possibility of enhancing efficiency of recombinant human growth hormone production we have modified the E. coli based expression system constructed for the expression of antimicrobial peptide LL-37 [38]. We have fused the codon optimized sequence of hGH with N-terminal thioredoxin gene, which is known to enhance solubility of proteins overexpressed in E. coli cytoplasm [42]. "
Article: High-level expression and purification of recombinant human growth hormone produced in soluble form in Escherichia coli[Show abstract] [Hide abstract]
ABSTRACT: Human growth hormone (hGH) was one of the first recombinant proteins approved for the treatment of human growth disorders. Its small size (191 amino acids), possession of only 2 disulphide bonds and absence of posttranslational modifications make Escherichia coli the host of choice for its production on any scale. In this work, we have utilized an efficient T7 based expression system to produce high levels of soluble thioredoxin-hGH (Trx-hGH) fusion protein. We outline a relatively simple three step purification process employing two immobilized metal-affinity chromatography and one anion-exchange steps and removal of fusion partner by enterokinase cleavage yielding native hGH. The ability of cell populations to produce quantities of up to 1 gram per liter of the soluble Trx-hGH fusion protein has been tested in flask cultivations as well as in batch and fed-batch bioreactor runs. The sequence and structure of derived hGH were confirmed by mass spectrometry and circular dichroism and its native function, to induce cell proliferation, was confirmed by employing a Nb2 cell line proliferation assay.Protein Expression and Purification 05/2014; 100. DOI:10.1016/j.pep.2014.05.003 · 1.70 Impact Factor
Science against microbial pathogens: communicating current research and technological advances, 3 edited by A. Mendez-Vilas, 12/2011: pages 992-1002; Formatex Research Center., ISBN: (13): 978-84-939843-2-8
- "Another alternative is to control production under an inducible promoter. [27] The heterologously expressed linear AMPs moricin [29], histatin-5 [30], sarcotoxin IA [31], cathelicidin (LL-37) [32] [33] [34], and also AMPs with more complex structural requirements, including disulfide bonds, such as lactoferricin [35], cecropin [36], and β-defensins [37] [38] have all been shown to be functionally active. Table 1 shows an overview of several currently described expression systems of EAP in bacteria. "
Article: Expression and Identification of Porcine β-Defensin 1 in Escherichia coli and Up-Regulation by Streptococcus Infection in Porcine Tongue In Vivo[Show abstract] [Hide abstract]
ABSTRACT: Defensins are members of a major family of antimicrobial peptides that play an important role in the innate immune response, which are of interest as potential novel pharmaceutical agents. We successfully constructed expression system of porcine β-defensin 1 (pBD-1) with his-tag in Escherichia coli Rossetta (DE3) cells and investigated the effect of Streptococcus ATCC 19714 infection on the mRNA expression of pBD-1 in porcine tongue in vivo. The results showed that active pBD-1 not to be affected by the presence of his-tag was obtained and displayed a high antimicrobial activity against Streptococcus ATCC 19714 at a concentration of 42 ± 5.2 μg/ml. The mRNA level of pBD-1 after infection in the tongue mucosa was initially changed with significant up-regulation at 3 h and reached the highest level at 6 h (about tenfold higher than 0 h), thereafter reduced to normal level at 12 h. The results indicated that pBD-1 is shown as a potent antimicrobial activity, and the expression level of pBD-1 against Streptococcus ATCC 19714 is up-regulation in the porcine tongue.International Journal of Peptide Research and Therapeutics 06/2012; 18(2). DOI:10.1007/s10989-011-9287-3 · 0.91 Impact Factor


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How Much Does JJ Abrams Know About Star Trek
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May 14 2013, 05:36 AM
Rear Admiral
Re: How Much Does JJ Abrams Know About Star Trek
Hound of UIster wrote:
BillJ wrote:
mos6507 wrote:
They may not have known a lot up front, but they did the proper research. Go read the old interviews and they'll talk about how they went back and watched the show--a lot. They just didn't egotistically move forward with their vision without knowing what came before. Sure, they changed things, but they were mindful of what they were changing.
And Orci & Kurtzman watched the shows and one of them is a fan of Trek Lit. I don't think geek cred is a barometer of whether someone is capable of making a good movie.
John Logan was a big fan...
I blame Berman.
There's enough blame to go around to encompass Baird, Berman and Logan. I think Berman was wrong in his creative calls maybe three-quarters of the time for 15 years or more, but on NEM, the lion's share belongs to Logan's actor-pandering shitwork and Baird still not acknowledging he has never had any business being on a set directing live-action.
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Tampa Bay Rays v Chicago White Sox
David Price of the Tampa Bay Rays pitches against the Chicago White... Nieuwsfoto'sAmerican League,Chicago,Chicago White Sox,David Price - Honkballer,Honkbal,Illinois,Inning,Sport,Tampa Bay Rays,U.S. Cellular Field,Verenigde Staten,Verticaal,WerperPhotographer David BanksCollection: Getty Images Sport 2013 Getty ImagesCHICAGO, IL - APRIL 28: David Price #14 of the Tampa Bay Rays pitches against the Chicago White Sox during the first inning on April 28, 2013 at U.S. Cellular Field in Chicago, Illinois. (Photo by David Banks/Getty Images)


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The Larimore plantation is a gorgeous venue for a wedding! Dena and Allen do a wonderful job of helping to make the day run smoothly!
Dena and Allen were great to work with. They really helped make our day beautiful and special. It was very nice to take advantage of all the extras they have to offer since we were planning the wedding from out of town (DJ, reception decorations, wedding cake, etc.) I felt like the cost of the wedding was a bargain compared to having traditional church wedding and reception later in the evening at a different venue. Dena was kind enough to notice one of my grandmothers had trouble walking down the front steps of the house, so during the wedding party entrance Dena helped her without being asked. During the reception, Allen noticed that a few of the groomsmen had taken their jackets off and asked if he needed to turn down the air conditioning which was very nice of him. The food was absolutely delicious and their recommended DJ was very personable and really made sure to play the music we wanted. I could not be happier with how everything turned out and would definitely recommend the Larimore House Plantation! Even though the venue is a little bit of a drive for a lot of the St. Louis area, it is definitely worth it (especially with the ceremony and reception all in one place). The only downfall is there is not a lot of time for pictures, but our photographers worked fast and had a plan of action so if you are prepared this is no big deal.
Perfect Perfect Perfect!!! Dena and Allen have really figured out the winning formula for a perfect wedding. My husband got married Sunday April 26, 2015 and it was the best day I could have ever imagined. From the beginning, Dena was extremely helpful and is always happy to listen and help in any way she can. The rehearsal went smoothly because she helped us with the line up, the details, and she worked great with our officiant, taking notes to make sure everything went as planned. The staff cleaned the chairs outside before the guests arrived, they were quick to help with anything we needed, and were extremely kind and attentive. I simply cannot believe how amazing they were to us. My husband and I didn't have to worry about absolutely anything all day. Trust me, Dena and Allen know how to make any wedding perfect. If you want a beautiful wedding in a short amount of time with a wonderful line up of vendors (Cake...AMAZING, DJ...SUPERB, Flower...all of it!!!!!!), take a trip to Larimore and talk to Dena. You will be thrilled that you did!
Everything about our wedding day was perfect! We could not have asked for a better venue on a better day. From start to finish, I did not have to worry about anything. Dena and her staff had everything taken care of for me. I think the perfect touch was at the end of the night when we were exhausted, her staff without even asking volunteered to help us clean up and take our things out to the car. This was very thoughtful and very appreciated! I would highly recommend having your event at Larimore!!
Dena did an amazing job on making my wedding day special.
My husband and I got married here last month and it was just perfect. The ceremony, the reception, the DJ, everything was perfect. Dena and Allen were amazing to work with and very helpful with planning our special day.
Dena is friendly and easy to work with.
The banquet center is elegant and provides a romantic ambiance. We had a blast at our reception as the food was delicious and the DJ listened to our song requests. I definatly reccomd this location for a reception.
I cannot say enough about Dena and Allen and Larimore House Plantation. They coordinated everything for us. From the DJ to the cake to the bar service to the hotel, everything was exemplary. It may seem like it's "too far north", but it's truly a perfect location for a wedding. The grounds are beautifully kept and the banquet hall is perfect. The food is wonderful and everything went off without a hitch. Perfect is just what it was.
I have absolutely no complaints. I contacted them 6 months before I wanted to get married and they were so easy to work with and made my wedding planning extremely easy. The day of, I was a stressful bride but Dena and Alan made the day amazing. It was a beautiful wedding.
They worked with Lori and I on everything and were very helpful. It was like having a wedding planner at no
additional charge. Everyone said the venue, food and service were great!!!! I would advise any bride wanting
a beautiful garden wedding to choose Larimore House. I would also advise the mothers of future brides to use Larimore House, there were a couple of goofs on the part of a vender and family member, I was quite upset
until I spoke with Deena who had me calmed down and the situations handled with a great deal of tact .
Due to their efforts, I got to enjoy my daughters wedding. Thanks Larimore House!!!
My husband and I were married September 14th of this year at the Larimore House Plantation. This venue truly gave me a fairy tale wedding. The grounds are beautiful, the service from Dena and Alan is prompt and professional, and I can't imagine getting married anywhere else in St. Louis. If you are looking for something 'outside' of the box go check them out-it's worth it!
Augst 3, 2013 was a very special day for our family as our youngest daughter was getting married. She did not have a lot of time to plan everything as she was in her Masters program at college. Dena and everyone at the Larimore House made that day one to remember. Everything just flowed together and our guests kept coming to us to compliment us on the venue, the food and the beauty of the location. We as her parents were able to relax and enjoy the day along with everyone else because of Dena taking care of seeing that all was right for the day. Absolutely the BEST!!! Thank you to the Larimore House. Randy and Colleen Bode
Dena and Allen were fantastic! I didn't have to worry about a thing, even though it kept raining! When we decided to have the ceremony outside, their staff dried off the seats and the ceremony went on! I couldn't have asked for a better venue!
I am so happy my fiancé and I chose to get married and celebrate at the Laromore House! It was the perfect venue to hold our vintage ceremony and reception. Our day went off without a hitch and our guests were so pleased with the Larimore House's grounds and amenities. Dena allowed me to be creative as I wanted to be while being so flexible and accommodating. If you are the less creative type, Dena is there to assist you in every detail! I highly recommend the Larimore House!
ABSOLUTELY have your wedding and/or reception here!! I suppose I would like to start by saying "THANK YOU!" From the time I met Dena, I thought she was great! She is always smiling and cheerful. Through every twist and turn of the planning process, she was there answering my questions quickly by either email or a pleasant phone call. Anytime we stopped by to go over details or to just take a look around, her and her husband, Allen, would take time to chat with us, tell us about their beautiful historical property, or just talk to us about marriage, kids and life. We have grown to respect them for what they do for their clients and who they are as people. As far as the actual day went, I could not have asked for anything better!!! We started off our reception (our wedding was held at a Cathedral, due to Catholic rules) by greeting our guests in front of the beautiful house with hors d'oeuvres and punch. Our guests kept telling us how beautiful the property was and they were so impressed that St. Louis offered such a unique venue. Allen and Dena also worked with us and allowed us to set up croquet, bag toss and washers for our guests to entertain themselves with if they so chose (they also let my mom put up a snack table in the bar area filled with homemade treats!). The grounds also provided a stunning backdrop for many of our cherished wedding photos. Once we were announced into the reception, our guests were served a spinach salad (we have had multiple requests by guests to see if we can get a hold of the dressing recipe!) followed by apricot chicken or sliced beef with new potatoes and vegetable medley. We are still receiving compliments about the food, all saying it was the best wedding food they had ever experienced!! The cake was amazing as well, made by Wedding Wonderland (Cherry Chip, Marble & Lemon). Even the DJ (All About Music) was fantastic! He ended the reception with "American Pie" to which all the guests sang along! It was perfect!!!
Amazing! From start to finish Dena made me feel comfortable, answered all questions, and went above and beyond to make our wedding perfect. They did everything possible so that we could have our ceremony outside, which the weather cooperated for just long enough for some pictures and the ceremony itself! The grounds are gorgeous for photos, the indoor and outdoor ceremony locations are beautiful, and their staff was very professional. Our guests were so impressed by the location and couldn't stop gushing about how great the food was. Thank you for everything!!!
-Kristen and Brad Conard


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Great series. I now have all the Ethan Gage series and each one has gotten better. I hope Dietrich keeps them coming.Published 2 months ago by B. Parris
History woven well with fiction, action and charming characters. Intrigue in unveiling secrets of ancient Egyption with adventure and suspense and treachery.Published 4 months ago by Carl R D'Agostino( DAG)
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Auxiliando o surdo em sua inclus...
Auxiliando o surdo em sua inclusão na sociedade !
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When deleting cells it calls my setEditing:animated: method which i have overridden because I need to adjust the height of my cells when editing, but because of this when I press the edit button the slide in animation of the red circles with the minus signs don't occur, instead they just appear into the cell. How Can I fix this?
This is my setEditing:animated code at the moment
- (void)setEditing:(BOOL)editing animated:(BOOL)animated{
[self.tableView setEditing:editing animated:YES];
[self.tableView reloadData];
[super setEditing:editing animated:animated];
Any help will be appreciated! Thanks