text:
Page 1
Oxidation of the Guanine Nucleotide Pool Underlies Cell Death
by Bactericidal Antibiotics
James J. Foti1, Babho Devadoss1, Jonathan A. Winkler2, James J. Collins3,4, and Graham
C. Walker1,*
1Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
2Program in Molecular Biology, Cell Biology, and Biochemistry, Boston University, Boston, MA
3Howard Hughes Medical Institute, Department of Biomedical Engineering, and Center for
BioDynamics, Boston University, Boston, MA 02215, USA
4Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02118, USA
A detailed understanding of the mechanisms that underlie antibiotic killing is important for the
derivation of new classes of antibiotics and clinically useful adjuvants for current antimicrobial
therapies. Our efforts to understand why DinB (DNA Polymerase IV) overproduction is cytotoxic
to Escherichia coli led to the unexpected insight that oxidation of guanine to 8-oxo-guanine in the
nucleotide pool underlies much of the cell death caused by both DinB overproduction and
bactericidal antibiotics. We propose a model in which the cytotoxicity of beta-lactams and
quinolones predominantly results from lethal double-stranded DNA breaks caused by incomplete
repair of closely spaced 8-oxo-deoxyguanine lesions, while the cytotoxicity of aminoglycosides
might additionally result from mistranslation due to the incorporation of 8-oxo-guanine into newly
synthesized RNAs.
Elevated levels of reactive oxygen species (ROS), such as superoxide, hydrogen peroxide,
and hydroxyl radicals (OH•), within prokaryotic cells potentiate cell death. For example,
three different classes of bactericidal antibiotics (β-lactams, quinolones, and
aminoglycosides), regardless of macromolecular target, ultimately result in cell death in both
Gram-negative and Gram-positive bacteria via a common mechanism that produces OH• (1).
Since elevated intracellular levels of OH• can damage DNA, lipids, and proteins, generalized
oxidation catastrophe could result in cell death; however, our current work suggests that cell
death is predominately elicited by specific oxidation of the guanine nucleotide pool and its
subsequent use in nucleic acid transactions.
DinB Overproduction Lethality Due to 8-oxo-dG Incorporation
The ribonucleotide reductase inhibitor hydroxyurea, although best known for stalling DNA
replication forks and eliciting double-strand DNA breaks (DSBs), also causes bacterial cell
death through the production of OH• (2). This stimulated us to test whether the cytotoxicity
associated with overproduction of the E. coli translesion DNA polymerase DinB (DNA Pol
IV) might result from an OH•-dependent process, because, like hydroxyurea, it slows the
speed of replication forks and results in bacterial cell death presumably because of DSBs (3,
4). To test if OH• radicals underlie cell death resulting from DinB overproduction, we
*To whom correspondence should be addressed email@example.com.
NIH Public Access
Author Manuscript
Science. Author manuscript; available in PMC 2012 October 20.
Published in final edited form as:
Science. 2012 April 20; 336(6079): 315–319. doi:10.1126/science.1219192.
NIH-PA Author Manuscript
NIH-PA Author Manuscript
NIH-PA Author Manuscript
Page 2
measured cell survival in the presence of thiourea (OH• scavenger) and 2,2′-dipyridyl (an
iron chelator which prevents the Fenton reaction required for OH• production) (5–8).
Thiourea and 2,2′-dipyridyl, which do not strongly effect cell growth (1), completely
prevent cell death caused by DinB overproduction (Fig. 1A). In addition, DinB
overproduction is not toxic in an anaerobic environment (Fig. 1B), consistent with OH•
mediating DinB-induced cell death. However, in contrast to hydroxyurea, which
significantly increases intracellular OH• levels (ca. 10 fold) (2), DinB overproduction has a
more modest effect (ca. 1.6 fold) (Fig. 1D). Thus it seemed most likely that the elevated
levels of DinB were lethal because of the increased use of oxidized deoxynucleotides, rather
than because of the induction of high levels of OH•.
The nucleotide pool is a significant target of ROS and guanine is particularly susceptible to
oxidation due to its low redox potential (9, 10). One of the most intensively studied major
products of guanine oxidation is 7,8-dihydro-8-oxoguanine (8-oxo-guanine) (10). 8-oxo-dG
is potentially mutagenic because of its ability to base-pair with both cytosine and adenine
(Fig. S1). DinB, like its human ortholog DNA Pol κ (11), is a translesion DNA polymerase
that can utilize 8-oxo-dGTP as the incoming nucleotide, pairing it with either dC or dA, with
a preference for dA (Fig. 1C). Mutation of DinB's steric gate (F13V) severely reduces its
ability to utilize 8-oxo-dGTP as an incoming nucleotide (Fig. 1C), as does mutation of the
corresponding steric gate of Pol κ (Y112A) (11). Therefore, to test the hypothesis that DinB
overproduction causes cell death by incorporating more 8-oxo-dG than the cell can tolerate,
we overproduced DinB F13V, and as predicted, observed that this variant is not cytotoxic
(Fig. 1A).
Although the observation that DinB F13V is not cytotoxic is consistent with our hypothesis
that DinB overproduction is incorporating more 8-oxo-dG than the cell can handle, it does
not exclude the possibility that the ability of DinB to copy over N2-dG adducts (12) is
contributing to cell death. Therefore, we co-overproduced MutT, a nucleotide sanitizer of
the GO system that, together with MutM and MutY, minimizes the deleterious effects of
oxidized guanine (13). MutT, which hydrolyzes 8-oxo-dGTP to 8-oxo-dGMP (13),
eliminates the cytotoxicity of DinB when co-overproduced (Fig. 1A). DinB overproduction
in a ΔmutT strain is as cytotoxic as wild-type (Fig. S2), suggesting that DinB levels are rate
limiting for death despite the fact that levels of 8-oxo-dGTP are extremely low even in a
ΔmutT mutant (14), a conclusion which is consistent, with trace amounts of 8-oxo-dGTP
usage during replication potentially having significant biological consequences (15).
Our results are consistent with the hypothesis that DinB is incorporating more 8-oxo-dG
than the cell can tolerate, but two potential mechanisms of intolerance are possible: the
accumulation of lethal mutations or the formation of lethal DSBs. It is unlikely that ca. 50%
of the cells have obtained a lethal mutation within 90 minutes (Fig. 1A), as DinB moves as
slow as 1 bp/second and thus has only copied ca. 5400 bp/replication fork (4). Instead, it
seems more likely that cells are dying from DSBs as previously suggested (3), a possibility
consistent with our observation that DinB overproduction results in the up-regulation of the
SOS response as measured by microarray analysis (Table S1 and S2) and cell filamentation
as measured by flow cytometry (Fig. 1D; 4.76 fold increase).
Although the absolute levels of 8-oxo-dG present in DNA in an unstressed ΔmutT strain are
too low to cause chromosomal fragmentation (16), a change in the levels of 8-oxo-dGTP
and/or a change in the ratios of the particular DNA polymerases operating in a cell (i.e.,
DinB overproduction in this case) could result in closely spaced 8-oxo-dG nucleotides.
Closely spaced DNA lesions are potentially problematic since the proximity of individual
DNA lesions can alter the ability of damage to be repaired (17) and subsequently result in
DSBs (18). A single DSB in an E. coli cell has been known for decades to be potentially
Foti et al.
Page 2
Science. Author manuscript; available in PMC 2012 October 20.
NIH-PA Author Manuscript
NIH-PA Author Manuscript
NIH-PA Author Manuscript
Page 3
lethal (19). Thus, in principle, incomplete base excision repair by MutM and MutY
glycosylases acting at closely spaced dC:8-oxo-dG and dA:8-oxo-dG pairs, respectively,
could result in the generation of a lethal DSB (Fig. S3). A DNA polymerase prone to
utilizing 8-oxo-dGTP as a substrate, such as DinB, would increase the likelihood of two 8-
oxo-dG lesions being incorporated in close proximity, and thus the potential for a DSB.
Direct incorporation of an 8-oxo-dG by a DNA polymerase close to an existing 8-oxo-dG
could also lead to a lethal DSB event via the action of GO system glycosylases (Fig. S3).
DSB formation by either of these mechanisms could be suppressed by MutT overproduction.
In principle, the occurrence of a closely spaced dC:8-oxo-dG and 8-oxo-dG:C pair as a
consequence of direct oxidation of DNA could also result in DSBs (Fig. S3), but these
would not be suppressible by overproduction of MutT.
The processivity of DinB interacting with the β-clamp is 300–400 nucleotides (20) and thus,
in principle, it could continue to replicate long enough to introduce multiple 8-oxo-dGs into
DNA, setting up the potential for a MutM/MutY-mediated DSB. Consistent with this model,
a ΔmutM ΔmutY mutant is less sensitive to the cytotoxic effects of DinB overproduction
(Fig. 1E). The protective effect of ΔmutM ΔmutY may be less than that of MutT
overproduction because other base excision repair enzymes that recognize 8-oxo-dG may
additionally contribute to DSB formation (13). In addition, it is possible that MutT is also
able to sanitize another oxidized dNTP, as can the human MutT homolog (21), and that its
incorporation into DNA contributes to DSB formation through a MutM/MutY-independent
process. Since cells repair DSBs by homologous recombination, the increased sensitivity of
a ΔrecA strain to DinB overproduction (Fig. 1E) is consistent with this model of 8-oxo-dG-
mediated DSB formation. Collectively, the above data suggest that incorporation of 8-oxo-
dG into DNA during replication is cytotoxic due to DSBs generated by the incomplete
action of base-excision repair systems designed to protect cells from the mutagenic effects
of oxidized nucleotides, i.e., the cellular protector has become the executioner.
Bactericidal antibiotic lethality due, in part, to the oxidation of guanine
We then wondered if the principle revealed by these experiments – an increase in closely
spaced 8-oxo-dG lesions leading to DSBs – might also underlie cell death induced by
bactericidal antibiotics. Antibiotics can generally be classified as being bacteriostatic
(preventing cell growth) or bactericidal (killing cells) (22). Bactericidal antibiotics had long
been thought to kill via class-specific drug interactions, which usually fall into three
categories: inhibitors of cell wall biosynthesis, DNA replication, and protein synthesis (23).
However, it was recently shown that a common pathway that produces OH• contributes
significantly to killing induced in Gram-negative and Gram-positive bacteria by major
classes of bactericidal antibiotics (1). Despite having different macromolecular targets, β-
lactams (cell wall synthesis inhibitors), quinolones (DNA gyrase inhibitors), and
aminoglycosides (protein synthesis inhibitors) generate OH• through the tricarboxylic acid
cycle, a transient depletion of NADH, destabilization of iron sulfur clusters, and a
stimulation of the Fenton reaction (1). Since OH• are the most powerful oxidizing agent in
living cells and have a half-life of nanoseconds (24), cell death could result from the
cumulative effect of oxidizing various classes of cellular molecules and macromolecules.
However, based on the insights we gained into the mechanistic basis of DinB
overproduction cytotoxicity, we hypothesized that, instead, the oxidation of the guanine
nucleotide pool is specifically responsible for much of the death caused by bactericidal
To test this hypothesis, we overproduced MutT in E. coli and treated with representatives of
the three different classes of antibiotics that increase OH•: ampicillin (β-lactam), norfloxacin
Foti et al.
Page 3
Science. Author manuscript; available in PMC 2012 October 20.
NIH-PA Author Manuscript
NIH-PA Author Manuscript
NIH-PA Author Manuscript
Page 4
(quinolone), and kanamycin (aminoglycoside). Strikingly, simply overproducing MutT was
sufficient to reduce the sensitivity of E. coli cells to killing by all three drugs, consistent
with the hypothesis that oxidation of the guanine nucleotide pool underlies much of the
cytotoxicity of bactericidal antibiotics (Fig. 2A and S4A). Similarly, over-production of
RibA, an alternative 8-oxo-dGTP sanitizer (25), was also sufficient to reduce sensitivity to
killing by ampicillin and norfloxacin (Fig. 2B). The inability for RibA to reduce the
sensitivity of cells to kanamycin (Fig. 2B) is probably the consequence of the block to
protein synthesis caused by kanamycin coupled with the inherent instability of the RibA
protein, which results in a substantial reduction of RibA protein levels after addition of the
drug (Fig. S5). In contrast, overproduction of NudB, a nucleotide sanitizer that preferentially
hydrolyzes 8-OH-dATP in vitro and has only a two-fold effect on mutation rate when over-
expressed in a ΔmutT mutant (26, 27), did not affect antibiotic sensitivity (Fig. 2C).
The amount of 8-oxo-dG incorporated into DNA is influenced by a combination of the
levels of 8-oxo-dGTP in the conditions being examined and the levels and characteristics of
the individual polymerases that are present. To gain insights into which of the E. coli
polymerases might be contributing to cell death from bactericidal antibiotics by
incorporating 8-oxo-dG into DNA, we tested the effect of mutating each polymerase on
ampicillin cytotoxicity (Fig. S6). Deletion of ΔdinB (DNA Pol IV) and ΔumuDC (DNA Pol
V) reduced killing by ampicillin suggesting that these two polymerases both contribute to
ampicillin sensitivity, whereas mutations of polA (DNA Pol I) or polB (DNA Pol II) had no
effect. The essential replication DNA polymerase Pol III is also involved in 8-oxo-dG
incorporation since an anti-mutator allele of the catalytic subunit (dnaE911), which
decreases the mutation frequency of a ΔmutT strain (28), also reduced ampicillin
cytotoxicity (Fig. S6). We then generated and tested a dnaE911 ΔdinB ΔumuDC triple
mutant, and observed a striking reduction in sensitivity to all three classes of antibiotics
(Fig. 2D and S4B), consistent with Pol III, Pol IV, and Pol V incorporating more 8-oxo-dG
than the cell can handle.
We hypothesized that the action of these polymerases under the conditions of elevated OH•
caused by the antibiotics could lead to increased 8-oxo-dG incorporation and hence a lethal
MutM/MutY-dependent DSB, as with DinB overproduction. We therefore treated a ΔmutM
ΔmutY strain with the three different classes of antibiotics and, as anticipated, observed a
significant decrease in killing consistent with the action of these base excision repair
enzymes resulting in DSBs (Fig. 3A and S4C).
Deletion of ΔrecA, which prevents DSB repair, has previously been shown to sensitize cells
to antibiotics (1). To test if the DSBs generated are repaired by the major RecA-dependent
RecBCD pathway, we introduced a ΔrecB mutant allele into cells and tested its effect on
antibiotic cytotoxicity. The ΔrecB mutant displayed approximately the same sensitivity as a
ΔrecA deletion, consistent with the hypothesis that the RecBCD pathway is utilized to
repair the DSBs that are generated as a consequence of 8-oxo-dG incorporation (Fig. 3B).
To further support our hypothesis that DSBs, many of which are MutM/MutY dependent,
are responsible for bactericidal cell death rather than being the result of DNA degradation in
dead cells, we utilized the terminal deoxynucleotidyl transferase dUTP end labeling
(TUNEL) assay. The TUNEL assay covalently attaches a fluorescent molecule to the 3′
terminus of a DNA molecule and, thus, can be used to directly measure DSBs. Thirty
minutes after antibiotic treatment of wild-type cells, a time at which little cell death has
occurred (Fig. 3C), we observe a qualitative increase in TUNEL positive cells when
analyzed by microscopy (Fig. 3D and Fig. S7). We then quantified the number of TUNEL
positive cells in wild-type and ΔmutM ΔmutY populations after antibiotic treatment via
flow cytometry (Fig 3E and G) and observed MutM/MutY-dependent DSBs. Moreover, the
Foti et al.
Page 4
Science. Author manuscript; available in PMC 2012 October 20.
NIH-PA Author Manuscript
NIH-PA Author Manuscript
NIH-PA Author Manuscript
Page 5
median TUNEL signal for the ΔmutM ΔmutY strain is less than that of wild-type cells after
treatment with antibiotics (Fig. 3F and 3H). Collectively, these results are consistent with
the hypothesis that bactericidal antibiotics lead to cell death largely by increasing the
number of DSBs, a significant fraction of which are MutM/MutY-dependent.
Extension of Common Mechanism Model
Based on the data described above, we are able to extend the model for a common
mechanism of cell death induced by bactericidal antibiotics. Instead of generalized oxidative
damage resulting in cell death, oxidation of the guanine nucleotide pool to 8-oxo-guanine
results in several lethal outcomes. The approximately equal degree of protection from killing
by β-lactams due to MutT overproduction, dnaE911 ΔdinB ΔumuDC, and ΔmutM ΔmutY
(Fig. 4) suggests that a significant portion of the bactericidal effect of β-lactams is due to
MutM/MutY-mediated DSBs that are a consequence of Pol III, Pol IV and Pol V
incorporating 8-oxo-dG lesions into the daughter strand during replication (Fig. S8).
Penicillin, a β-lactam bactericidal antibiotic, was the first antibiotic described and was
thought to kill cells primarily and specifically via inhibition of cell wall synthesis (23). It is
noteworthy, that our results suggest oxidation of guanine nucleotides also contributes to cell
death by penicillin (Fig. 4), thus providing a new insight into the mechanism of action of the
oldest known antibiotic. The approximately similar degrees of protection from killing by
norfloxacin due to MutT overproduction and dnaE911 ΔdinB ΔumuDC indicate that an
analogous mechanism is responsible for its bactericidal effects. However, the lesser degree
of protection afforded by ΔmutM ΔmutY (Fig. 4) suggests that DNA gyrase inhibition
additionally contributes to the DSBs caused by 8-oxo-dG incorporation (Fig. S8).
This 8-oxo-dG-dependent DSB mechanism accounts for some of the bactericidal effects of
kanamycin, as there is protection from killing by dnaE911 ΔdinB ΔumuDC and ΔmutM
ΔmutY. However, our observation that the degree of protection caused by MutT
overproduction is larger (Fig. 4) than that conferred by dnaE911 ΔdinB ΔumuDC or
ΔmutM ΔmutY, together with the relatively modest increases in sensitivity conferred by the
ΔrecA and ΔrecB mutants, suggests that an additional mechanism of cell killing is involved
in the case of kanamycin. The reduced involvement of the 8-oxo-dG-dependent DSB mode
of killing may, in part, be due to its translational inhibitory effects preventing the synthesis
of SOS-regulated proteins, including the dinB- and umuDC-encoded DNA polymerases,
other proteins required for stress responses, and antitoxins thereby leading to activation of
their cognate toxins. Nevertheless, the strong suppression of kanamycin cytotoxicity by
MutT overproduction suggests that, in addition to their known direct effect on the ribosome
(29), a substantial amount of the cytotoxicity caused by aminoglycosides in vivo is due to
oxidation of guanine nucleotides.
An intriguing hypothesis is that the protective effect of MutT overproduction is due to
MutT's ability to sanitize the guanine ribonucleotide pool (8-oxo-rGTP and 8-oxo-rGDP)
(30, 31) as well as the guanine deoxynucleotide pool (Fig S8). RNA polymerase is proficient
at using 8-oxo-rGTP as a substrate, incorporating 8-oxo-rG into transcripts at one tenth the
rate it incorporates rG (30). These potentially altered transcripts could lead to mistranslated
proteins, which is consistent with the previous observation that ΔmutT strains exhibit higher
levels of protein carbonylation (32), a consequence of protein mistranslation. Moreover, the
effect of 8-oxo-rGTP on protein mistranslation would be exacerbated by its
misincorporation into rRNA and tRNA, which would be expected to further reduce the
fidelity of protein synthesis. This potential for kanamycin-induced 8-oxo-rGTP-dependent
mistranslation of cell envelope proteins could, in turn, cause more membrane alterations
leading to increased drug up-take and further stimulation of the OH• radical pathway
through membrane stress two-component systems (Cpx) and changes in metabolic function
Foti et al.
Page 5
Science. Author manuscript; available in PMC 2012 October 20.
NIH-PA Author Manuscript
NIH-PA Author Manuscript
NIH-PA Author Manuscript


text:
Christmas - Page 7
World's Largest Christmas Tree Puts Yours to Shame [VIDEO]
Ho, ho, ho-ly cow.
Adorable Little Girl Signs Christmas Song So Her Deaf Parents Can Enjoy
One little girl did her part to spread some Christmas cheer to her parents.
A Look at How the Rest of the World Celebrates Christmas
Christmas traditions around the world can be quite different from what we're used to at home.
Luke Bryan, Darius Rucker Unintentionally Duet 'Jingle Bells' [Watch]
Although Luke Bryan and Darius Rucker didn't actually sing 'Jingle Bells' together, they still contributed to an unintentional duet, turning the Christmas classic into a decidedly country carol!
USDA Clears Santa Claus To Enter United States
The US Department of Agriculture's Animal and Plant Health Inspection Service has issued a movement permit to Mr. S. Claus of the North Pole, a broker with Worldwide Gifts, Unlimited. The permit will allow reindeer to enter and exit the United States between the hours of 6 PM December 24, 2013 and 6 AM December 25, 2013, through or over any northern border port.
Todd Harding's Christmas Letter 2013
Todd Harding shares his Christmas letter for 2013. Pictures included!
Jennifer Nettles Admits She's Behind on Christmas, Looking Forward to New Years
It's been a crazy year for Jennifer Nettles. Son Magnus turned a year old, the country songstress ventured out on a solo career and she and her husband are in the process of moving into a new home. Needless to say, Nettles is a little behind on Christmas.
Santa Tracker – The Best Ways Your Kids Can Follow Santa's Christmas Deliveries
The excitement of Christmas eve for many young children is unparalleled by most adult endeavors. How many times, as a parent, have you found yourself trying to explain how Santa delivers all those toys in one night...
Christmas Cards: What do you do With Them?
When I check the mail and see what must be Christmas cards, as it is that time of year, I get a bit like a kid and short of running into the house to open them I open them as soon as I get in the house.
Christmas Eve Church Services in Fort Collins, Loveland & Greeley
Looking for a place to celebrate Christmas Eve 2013? Here is a list of the churches around Northern Colorado that are holding services. (Including Fort Collins, Loveland, Greeley, Windsor, Berthoud and Johnstown.)
5 Scary, Creepy and Unsettling Things About Christmas
Christmas is the time of giving and families, but it also has a darker side.

subset: commoncrawl


text:
Description: samantha picture by juliswiftie13 - Photobucket
Image was hearted from s1266.photobucket.com
Other images from this site
2 people have hearted this image
You might like these too
Now available in your language!Use in your language! Go back to English
Other images from this site
You might like these too
Sign in with Facebook or Twitter to start your gallery.
Sign in with Facebook Sign in with TwitterDon't have Twitter or Facebook? Skip this step!


text:
Komaki City Hotel
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
TripAdvisor Reviews Komaki City Hotel
Travel Blogs from Komaki
Two nights in Nagoya
The reason why I stopped in Nagoya was basically a train museum which showed the history of the Japanes trains with a main focus of the Shinkansen trains. I have to say that these trains have been fascinating me since I received a card game as a kid where the Shinkansen train card ...
So, fresh off from Kyoto we headed our way to Nagoya with only objective to a Sumo competition!
We were lucky to get tickets months in advance because these events are very popular in Japan and sell out quickly. There are 6 tournaments per year in Japan, 3 in Tokyo, and 3 in the nearby provinces, including Nagoya, where the year's competition starts.
We arrived at the Gymnasium at noon and were guided to our seats... in lieu of ...
Nagoya, aka, Phil's day out!
... we took the subway to our hotel and dropped our bags off before setting out on Phil's itinerary.
First visit was to Nagoya Castle , five stories high in a huge park with good views of the city. Boy, it was hot inside and out and The locals are mopping themselves with their hand towels very frequently. The walls were all blocks of rock constructed similarly to pyramids and the roof lines were in a pagoda style with two huge solid hold statues on top. ...
Day 7
Well today we started off early no breakfast met our tour guide just to get to the station by taxi. Caught the Shinkansen (bullet train) to Nagoya 350klms per hr took about 2 hrs fantastic had breakfast on the train which we bought before we got on. Met new guide Akiko who will be with us for 3 days. Next rapid express (120ksph) to Takayama about 2 hrs. We arrived in Takayama & went straight to our ...
Osaka - Nagoya - Home
Final day of an amazing trip. Up early from Keiko's, Jim & Yosh accompany us to Osaka to board the bus that's taking us to Nagoya. Our first (and last) trip sans Jim in Japan so a bit nervous getting us to the airport in time. Arrived in Nagoya right on time, asked cabbie what it would cost to get us to the airport - ...
Other places to stay in Komaki
Meitetsu Komaki Hotel1-260 Chuo, Komaki | Hotelfrom $77
Castle Inn Komaki127 Akebono-cho, Komaki | Hotelfrom $71
Hotel Grantia Komaki2-33 Shin-koki, Komaki | 4 star hotelfrom $89
Komaki Central Hotel730 Kitatoyama, Komaki | Hotelfrom $54
Business Hotel Komaki3-287 Oji, Komaki | Hotelfrom $38


text:
Junior Kittel Evenson Named to U.S. Figure Skating Governing Body
Junior Kittel Evenson, Northfield Skating School Assistant Director, has accepted an invitation from U.S. Figure Skating headquarters to join the Basic Skills Sub-Committee, a governance and development group for the largest sub-section of the national governing body's membership. Evenson joins Northfield Skating School Founder/Director Carey Tinkelenberg on the twelve-person committee. The Northfield Skating School is the only program with more than one representative. Evenson's duties will include voting on rule changes, mentoring new directors, and discussing the future direction of the nation's 950 Basic Skills skating programs.
Majoring at Carleton in history, Evenson is a Nerstrand, Minn., native and former skater who was coached by Tinkelenberg through middle and high school. Evenson joined the Northfield Skating School staff in 2005 when the school was founded. She was hired as Assistant Director two years later during her freshman year at Carleton. Evenson has been an integral part of the school's development, leadership, and growth into a U.S. Figure Skating Model Program. Her committee invitation came following a presentation she and Tinkelenberg co-delivered at a U.S. Figure Skating Workshop co-hosted by the Northfield Skating School and Shattuck St. Mary Figure Skating Academy earlier this month.
For more information on the Northfield Skating School, call (508) 887-2551 or email firstname.lastname@example.com.
Previous Post
Minnesota Construction Association Honors Cassat and Memorial Halls with Two Top Awards
Next Post
Work by Diane Nemec Ignashev Reviewed in the Times Literary Supplement
Top Stories
The Latest
- Renowned cardiologist and medical historian to speak on The Origins and Evolution of the Mayo Clinic • Media Relations
- Walk with Nature (and Emerson/Thoreau) in Cowling Arboretum • Arts at Carleton
- Carleton, others form Coalition for College Access • Media Relations
- Summer BLAST Success at Carleton • Center for Community and Civic Engagement


text:
Second Quarter
Sino-Global Results for Q2 2009
Sino-Global Shipping America, Ltd. (NASDAQ:SINO) a leading, non-state-owned provider of shipping agency services operating primarily in China, announced selected unaudited financial results for its second fiscal quarter of 2009 ended December 31, 2008. Highlights for the second quarter of 2009: Revenues were US$4.5 million, an increase of 7.7% from $4.2m in the second quarter of 2008. Gross margin was 9.4%, compared to 20.9% in the second quarter of 2008. Basic and diluted losses per share were US$0.30, compared to basic and diluted earnings per share of US$0.20 in the same period in 2008. Despite the global economic downturn, the number of ships served increased to 47 from 44 in the second quarter of 2008. On October 9, 2008, Sino-Global announced a program authorizing the company to repurchase up to 10% of its outstanding common stock over a 12-month period. As of December 31, 2008, Sino-Global had repurchased 55,100 shares. These purchases reflect the Company's confidence in its future growth prospects. Mr. Cao Lei, Sino-Global's chief executive officer, said ''The second quarter proved to be a challenging one as the global economic crisis continued to take a toll on global demand for commodities and shipping to and from China. Despite this, we are seeing the results of our expansion strategy, which kept our top line growing in the face of challenging macro conditions
Earnings Down for Most Oil Companies
Many oil companies reported a decrease in net income for the second quarter, compared to the previous year's results, although - in most cases - the second quarter still outperformed the first. While the decreases ranged in percentage, only a few companies' results were virtually unchanged from the previous year's performance. However, higher crude oil prices resulted in many companies' exploration and production net income actually increasing over the previous year.
Cat Financial Announces Second-Quarter 2014 Results
Cat Financial reported second-quarter 2014 revenues of $728 million, an increase of $34 million, or 5 percent, compared with the second quarter of 2013. Second-quarter 2014 profit after tax was $146 million, a $35 million, or 32 percent, increase from the second quarter of 2013. The increase in revenues was primarily due to a $36 million favorable impact from higher average earning assets. Profit before income taxes was $206 million for the second quarter of 2014
Diamond Offshore 2Q Earnings Fall
Diamond Offshore Drilling Inc., the world's largest offshore oil driller by market capitalization, reported its second quarter earnings fell more than 50 percent. Net income dropped to $53.2 million from $111.7 million in the same period of 1998. Revenues for the second quarter fell to $215.3 million from $323.5 million in the second quarter of 1998. The company did not comment in its earnings statement on business during the second quarter or on the outlook for the remainder of the year.
General Dynamics Reports Q2 2013 Results
General Dynamics (GD) today reported second-quarter 2013 net earnings of $640 million, or $1.81 per share on a diluted basis, compared to 2012 second-quarter net earnings of $634 million, or $1.77 per diluted share. Second-quarter 2013 revenues were $7.9 billion. Company-wide operating margins for the second quarter of 2013 were 12.1%, consistent with second-quarter 2012 margins. Each of the company's four segments delivered margin expansion over the first quarter of 2013.
Arlington Tankers Announces Unaudited 2Q 2007 Results
Arlington Tankers Ltd. announced financial results for the second quarter and the six months ended June 30, 2007. For the quarter ended June 30, 2007, the Company's total revenues were $17.8 million, consisting of $16.5m in basic vessel charter hire and $1.3 million in additional charter hire that the Company received under its profit sharing arrangements. On the basis of the second quarter results, Arlington's Board of Directors has declared a cash dividend of $0.59 per share
General Dynamics Reports 2Q 2014 Earnings
General Dynamics today reported 2014 second-quarter earnings from continuing operations of $646 million, or $1.88 per share on a diluted basis, compared to second-quarter earnings from continuing operations in 2013 of $640 million, or $1.81 per diluted share. Second-quarter 2014 revenues were $7.5 billion. There is a charge in the quarter of $105 million in discontinued operations for the sale of a business within Combat Systems
Arlington Tankers Q2 Profit Increases 35%
Arlington Tankers Ltd. reported an increase in second quarter profit helped by a $7.3 million unrealized gain, even as revenue decreased from the prior year. The company declared a dividend for the quarter. Second quarter net income for , Bermuda-based increased 35% to $11.52 million or $0.74 per share from $8.53 million or $0.55 per share from the same quarter a year ago. The company recorded a gain on interest rate swap of $7.28 million in the second quarter of 2008.
Kirby Q2 2009 Results
Kirby Corporation (NYSE:KEX) announced net earnings for the second quarter ended June 30, 2009 of $33.7 million, or $.63 per share, compared with net earnings of $40.3 million, or $.74 per share, for the 2008 second quarter. Kirby's published 2009 second quarter guidance range was $.52 to $.62 per share. Consolidated revenues for the 2009 second quarter were $272.7 million compared with $348.3 million reported for the 2008 second quarter.
Knightsbridge Tankers Announces 2Q Results
Knightsbridge Tankers Limited reported net income of $7.9 million and earnings per share of $0.46 for the second quarter of 2006. The average daily time charter equivalents earned by the company's five VLCCs was $42,800 compared with $54,300 in the immediately preceding quarter. The second quarter earnings reflect the weakening of the tanker market that occurred in the first quarter and early into the second quarter of 2006 before a steady recovery that continued through the end of the
Seanergy Maritime 2Q Revenue Nets $1.8 mln
Dry bulk shipper Seanergy Maritime Holdings Corp. announced its financial results for the second quarter and six months ended June 30, 2015. For the three months ended June 30, 2015, the company generated net revenues of $1.8 million. Total equity as of June 30, 2015 was $9.4 million.
US Oil Drillers Cut Rigs for Third Week on Weak Crude Prices
U.S. energy firms cut oil rigs for a third week in a row this week, data showed on Friday, a sign the latest crude price weakness was causing drillers to put on hold plans announced several months ago to return to the well pad. Drillers removed 8 rigs in the week ended Sept
Seadrill Cancels West Mira Construction Contract
Offshore drilling company Seadrill Limited said it has exercised its right to cancel the contract for the construction of the West Mira drilling unit following builder Hyundai Heavy Industries Co Ltd.'s inability to complete the project on deadline.
LNG Terminal in Poland Will be Ready This Year
Świnoujście terminal which is designed to reduce Poland's dependence on natural gas imported from Russia will be completed by the end of the year, Polskie LNG, a company designed to conduct the investment, informed in a press release.
CMA CGM's Profits Jump 67% in Q2
French shipping giant CMA CGM, reported a 66.7% jump in net profit to $156m in the second quarter of 2015. The result compared to a $94m net profit in the same period a year earlier. The world's third largest container line says that its unit costs fell 10
CMA CGM 2Q Post Higher Profit
In the second quarter, CMA CGM demonstrated the strength of its business model by significantly outperforming the market, despite a sharp fall in freight rates and industry overcapacity: * Volumes carried during the second quarter increased by 6.2% year-on-year, to 3
Maersk Group Optimistic on $4Bln Profit Target
AP Moeller Maersk Group has continued to fix its eyes on its forecast of a $4 billion profit for 2015, despite the challenges it is facing in its operating environment, according to Thisday Live. The group said in a statement that from its records
Odfjell Reports Best Quarter Since 2008
In what it is calling its best quarterly performance since third quarter 2008, the Odfjell Group for the second quarter of 2015 reported net results of $7 million. The group, which transports and stores bulk liquid chemicals, acids, edible oils and other special products
Diana Shipping Fixes Panamax
Diana Shipping Inc., a global shipping company specializing in the ownership of dry bulk vessels, today announced that, through a separate wholly-owned subsidiary, it entered into a time charter contract with Transgrain Shipping B.V., Rotterdam, for one of its Panamax dry bulk vessels
GC Rieber Shipping Earns Well
GC Rieber Shipping has more than doubled its net profit for the second quarter and recorded a year-on-year increase in profit on more vessels in operations and currency gains. However it has warned of a continued focus on shorter contracts in the future.
Farstad Shipping Dives into Loss
Norway's Farstad Shipping ASA has seen red in the second quarter of 2015 as impairments and currency losses drove the company into a loss. Farstad's profit after taxes (PAT) was negative NOK 119.5 million, versus positive PAT of NOK 46.7 million a year earlier
Diana Shipping Extends Charter for Crystalia With Glencore
Diana Shipping Inc., has, through a separate wholly-owned subsidiary, agreed to extend the present time charter contract with Glencore Grain B.V., Rotterdam, for one of its Ice Class Panamax dry bulk vessels, the MV Crystalia.
Hapag-Lloyd Advances Listing Plans to September
German container shipping group Hapag-Lloyd aims to launch preparations for a stock market flotation in September, earlier than initially planned, four sources familiar with the transaction told Reuters on Thursday. That would permit the company's shares to trade on the Frankfurt stock exchange
EMGS 2Q Revenue Falls
Electromagnetic Geoservices ASA (EMGS) recorded revenues of USD 12.1 million in the second quarter 2015, down from 32.3 million in the previous quarter and from USD 42.5 million in the second quarter 2014. Contract sales ended at USD 4
Conrad Industries 2Q Revenue Shrinks
Conrad Industries, Inc. announced today its second quarter and six months 2015 financial results and backlog at June 30, 2015. For the quarter ended June 30, 2015, Conrad had net income of $1.2 million and earnings per diluted share of $0.21 compared to net income of $6


text:
So sorry, but only 4 items are allowed for comparison. I blame the gnomes and so should you.
Would you like to compare the products you have selected now?
So sorry, but this item is sold out.
You probably would've looked amazing with it too.
We do have some similar items available right now though.
Check out Mens BackpacksView Other Similar Stuff
Moosejaw Staff Pick - Steve, Moosejaw Secret Headquarters
|Best Use:
|Backpacking, Ultralight Backpacking, Trekking
|Fabric Details:
|Pack Capacity:
|60 liters / 3661 cubic inches
|Torso Range (Medium):
|21 - 24 in.
|34 oz
|Weight (Large):
|36 oz
|Weight (Medium):
|34 oz
|Weight Capacity:
|35 lbs
|Pack Capacity (Large):
|65 Liters / 4000 Cubic inches
|Torso Range:
|18 - 21 in.
|Torso Range (Large):
|21 - 24 in.
|Pack Access:
|Pack Features:
|Hydration Compatible, Ice Axe / Trekking Pole Loops, Hip Belt, Sternum Strap
|Weight (Small):
|32 oz
|Moosejaw Staff Pick
|Frame Type:
Free Shipping
Spend $12 in Moosejaw products OR at least $49
in other products and you orders ships FREE!
Moosejaw Rewards
You earn $1 in Rewards for every $10 you spend
at Moosejaw.com and our shops (half for discounted items).


text:
Religious Celebrations
Wedding Celebrations
Milestone Celebrations
Upcoming Holidays
Corporate Party
Party Ideas & Inspiration
Please upload a photo that has a resolution of at least 0 dpi at its print size and is in one of the following file formats: . The file must not exceed 10MB. Beau-coup will not crop or retouch your photo and is not responsible for the quality of uploaded files. By uploading an image, you agree to our terms and conditions.
1. Customer is responsible for owning the copyright or having permission from the copyright holder for all images uploaded to this website. Customer agrees to hold Beau-coup harmless from any claim arising out of the use of copyrighted material.
2. Beau-coup may choose not to publish any images found to be offensive.
REVIEW SNAPSHOT®by PowerReviews
(based on 17 reviews)
of respondents would recommend this to a friend.
Best Uses
Reviewed by 17 customers
Sort by
Displaying reviews 1-5
Previous | Next »
Sheer Elegance
Best Uses
Comments about Beau-coup Falling Snow Holiday Ornament Place Card Holders:
These are so darling!! I ordered two sets and may order more after Christmas IF they are still available! I have dinnerware service for eighteen and would like to have equal place mark settings. These are perfect in every way!!
Bottom Line Yes, I would recommend this to a friend
Exactly as advertised
Best Uses
Comments about Beau-coup Falling Snow Holiday Ornament Place Card Holders:
Paper crafted a beautiful thank you for each place setting, tied a ribbon on, and these made a beautiful addition to my winter baby shower place setting. Baby it's cold outside!
Bottom Line Yes, I would recommend this to a friend
Snowing review
Best Uses
Comments about Beau-coup Falling Snow Holiday Ornament Place Card Holders:
Everyone was very impressed with the holders and were asking where I purchased them.
Bottom Line Yes, I would recommend this to a friend
I have not yet received my order.
By Nanci
from Littleton, Colorado
About Me Midrange Shopper
Best Uses
Comments about Beau-coup Falling Snow Holiday Ornament Place Card Holders:
I have not yet received my order.
Holders are not just for weddings
Best Uses
Comments about Beau-coup Falling Snow Holiday Ornament Place Card Holders:
Even though these card holders are small they are perfect for our doll club luncheon. We will have many items on the table and the holders are small enough to show our guests where to sit but they do not overpower the table. These are exactly what I had envisioned for our luncheon. I think they should be offered in at least 2 sizes.
Bottom Line Yes, I would recommend this to a friend
Displaying reviews 1-5
Previous | Next »
This winter, bring the beauty of the outdoors indoors with these falling snow ornament place card holders. With each touch, a flurry of faux snowflakes swirls within. Set these party decorations beside guests' place settings at your holiday party, and let the snow-globe fun begin!
Designed to look just like a holiday ornament, each glass globe has a silver clip on top—slip a place card or photo right in! The clear exterior is decorated with powder-white flocked snowflakes, revealing the faux snowdrift inside. Set of six includes matching place cards. Ornament measures 3.5"H including card; measures 2"H without card.
For other great favor ideas, take a look at our selection of holiday party favors.
Processing time is the time from when the order is placed to when it leaves our warehouse. This varies by product.
Shipping time is the time from when the package leaves our warehouse to when it arrives at your door. This varies by shipping method.
In a rush? See items that ship same day or next business day. Click here.
Shipping internationally? Read our International Orders FAQ for information on custom duties, export restrictions and more.
* Shipping options and estimated delivery dates apply to orders shipping within the 48 contiguous United States only.
Shipping Charges
Rules & Exceptions
Vintage Baroque Place Card Holder
Vintage baroque place card holders are a classic way to welcome wedding guests to their seats. They're full of vintage appeal thanks to the intricate baroque design and antique copper coloring. Simply insert the included blank place card and ... View Product
Love Bird Place Card Holders
Guests won't simply fall in love with these lovebird place card holders, they'll fly in love! Delightfully designed and completely irresistible, you'll want to use and reuse these place card holders at every bridal shower, wedding and engagement party. ... View Product
"Le Tour" Bicycle Place Card/Photo Holder
Your tour de love deserves "Le Tour" bicycle place card/photo holders! These mini bicycles perfectly hold up place cards for guests' assigned seating, or can be used to hold up sentimental photos of the newlyweds as a nostalgic piece ... View Product
Nautical Anchor Place Card/Photo Holder
Nautical anchor place card/photo holders are the perfect accessory for your beach or nautically-themed wedding. Beautifully decorated with an antique silver finish, these miniature anchors will perfectly display place cards for assigned seating or personal photos for a sentimental ... View Product
This item has one or more options that are currently out of stock. If you would like to be notified by email when it becomes available, please enter your email address below.
|Celebrating life, one event at a time.
|We believe in celebrating life - every occasion, every milestone, every laugh, smile and tear. We know that sharing these moments makes them extra special, and we want to be there to help you celebrate life, one event at a time.


text:
- UHS-1/Class 10
- 32GB Ultra small storage device for mobile phones, digital cameras, digital music players, GPS, automotive recorders and camcorders
- SD Adapter included Fully compatible with SD 2.
- $19.99 19.99
- $13.99 –
- Save: $6.00 (30%)
- $0.99 Shipping (restrictions apply)
Much slower than expected 12/17/2012
This review is from: G.SKILL 32GB microSDHC Flash Card w/ SD Adapter Model FF-TSDG32GA-C10
"No, no Light Speed is too slow! We're going to have to go right to Ludicrous Speed!" Consistently getting over 14 MB/s on write tests. Similarly, ludicrously low price.
I did have some trouble at first. I wanted to use this in my phone (Galaxy Sii, rooted, CM9) using ext4. I couldn't get write speed on via the phone or my laptop (with the full size SD adapter) to the card above 6 MB/s. Same thing with NTFS. Finally I formatted it back to FAT32(LBA) and after some exercising the card it magically began to more than double those earlier write speeds. I suppose I can leave it with the FAT32, since I don't really plan on having files over 4GB on it. Fast > Cool.
2 people found this review helpful. Did you? Yes / No Thanks for the valuable feedback you provided!


text:
Physicians Resource Network Inc. has been recognized in peer voting as the No. 1 company in the country among DOTmed's 100 top equipment sellers. more
By PBN Staff
Alex Marszalkowski started a business this year that combines two aspects of his work life. He's a real estate attorney, employed by Paolino Properties in Providence. He's also a farmer, part of a family that has run the 200-acre Adams Farm in … more
Despite state regulators calling ride-hailing-app companies, such as Uber and Lyft, "wholly illegal," it's unlikely the popular taxi-like services will be shut down anytime soon in the Ocean State. The advent of the ride-hailing apps, known … more
By Eli Sherman | email@example.com | 6/5/15
Misty Delgado left corporate employment to become a fellow at the Center for Justice, a new, independent nonprofit dedicated to public-interest law and helping people on low incomes get legal representation. Delgado's clients include a … more
The School of Law at the University of Massachusetts Dartmouth is expanding its Justice Bridge law practice incubator to New Bedford and Taunton, made possible through a three-year $225,000 grant from Bristol County Savings Bank. more
By PBN Staff
Engineering firm Wright-Pierce received a Circle of Excellence Platinum Award at the 2014 A/E/C (architecture/engineering/construction) Industry Summit held in Orlando last month. more
By PBN Staff
Dawn breaks cold and ugly at Boston's sprawling 10-acre public works headquarters as Mike Dennehy, commissioner and unofficial "snow czar," readies for a quick- moving squall with a bag of high-tech tricks. more
By Tom Moroney
Despite a travel ban and the Rhode Island governor advising residents to stay in and "hunker down," some business owners decided to brave the storm Tuesday and open their restaurants. … more
By Eli Sherman
Northeast Collaborative Architects has expanded its business with a new office in Washington, D.C., the company announced Thursday afternoon. more
By Mary MacDonald
Creating a signature building for the gateway to the I-195 Redevelopment District in Providence was a recent design challenge for Kite Architects. more
By Mary MacDonald


text:
Sort by
Bound Gang Bangs Porn Videos
- 151
- 169k
- 3 years ago
- 94 10094
Bound Gang Bangs - the site where these dirty sluts are tied up and humiliated by a bunch of mean cocks. Ropes, gags or straps, these little whores are gonna get what's coming to them.........or should that be 'cumming'?. View Site »


text:
Dodge Magnum Wiper Blades
When you are looking for great accessories to help make your Dodge Magnum an even better, safer vehicle, CARiD has a wide range of excellent products from the best names in the industry. Backed by fast delivery and excellent customer service, you know you are making the right choice when you buy all your new Dodge Magnum parts and accessories right here. Just take a look at this fabulous selection of Dodge Magnum windshield wiper blades. These wiper blades for your Dodge Magnum are easy to attach to the Magnum, allowing you to get on with driving your great Dodge.
New Dodge Magnum windshield wiper blades ensure that you can see properly in all kinds of wet weather, including snow, sleet and of course rain. This is an essential part of getting the Magnum ready for winter, though heavy rain can come at any time of year so it is crucial to make sure your Dodge always has effective, well conditioned Dodge Magnum wiper blades. Our range includes lots of great Magnum wiper blades from makes you know and trust like Michelin and Rain-X, and at great prices, so check them out here and choose yours today!
- Rain-X® Latitude™ Wiper BladeLatitude™ Wiper Blade by Rain-X®. These wiper blades enable you to drive safely in rain, sleet and snow. The contoured beam ensures that the blade hugs the windshield for streak-free visibility, and the graphite blade delivers a...$17.31 - $21.28
- Rain-X® Weatherbeater™ Wiper BladeWeatherbeater™ Wiper Blade by Rain-X®. Clearly see the road regardless of the weather with Weatherbeater Wiper Blades. Multiple pressure points along with embedded friction reducers apply even pressure on the wiper blade across...$7.49 - $15.90
- Trico® Force™ Wiper BladeForce™ Wiper Blade by Trico®. Tired of keeping your speeds down when your wiper blades lift clear of the windshield on windy days? Air speeds over your windshield can be double the speed your speedometer shows, thanks to strong...$21.15 - $34.70
- Trico® Exact Fit™ Wiper BladeExact Fit™ Wiper Blade by Trico®. Trico Exact Fit™ replacement blades make it easy to restore your vehicle to original factory quality. Made from the finest quality natural rubber and high-strength steel, they offer...$10.77 - $38.61
- Trico® Ice™ Wiper BladeIce™ Wiper Blade by Trico®. Trico® Ice™ has a specially designed, ruggedly constructed, synthetic-blended armor that is infinitely flexible and protects critical wiper components from ice and snow.$15.64 - $25.69
- Michelin® Rainforce™ Wiper BladeRainforce™ Wiper Blade by Michelin®. Get superior, streak-free, and quiet wiping at an exceptional value. The traditional, heavy-duty, all metal riveted frame applies even pressure across the entire blade, for a complete,...$7.49 - $14.49
- Bosch® ICON™ Wiper BladeICON™ Wiper Blade by Bosch®. Replace your original equipment windshield wipers with innovative, top-grade wiper blades that ensure maximum visibility, no matter the weather. Designed to apply more uniform pressure along the...$20.23 - $28.07
- Bosch® Clear Advantage™ Wiper BladeClear Advantage™ Wiper Blade by Bosch®. Clear Advantage is your ultimate choice in rain, sleet, and snow. The precision-tensioned mono steel delivers all-weather wiping performance with uniform pressure for consistent, high...$9.87 - $11.92
- Michelin® Stealth™ Hybrid Smart Flex Wiper BladeStealth™ Hybrid Smart Flex Wiper Blade by Michelin®. Drive safely under the harshest weather conditions with these hybrid wiper blades. They combine the windshield hugging features of a conventional spring loaded blade with the...$11.66 - $15.99
- Bosch® DirectConnect™ Wiper BladeDirectConnect™ Wiper Blade by Bosch®. Make your driving safer and more pleasurable with DirectConnect wiper blades from Bosch. The precision-cut natural rubber wiping edge is capable of removing even the smallest droplets for...$7.35 - $8.44
- Pilot® Performance Wiper BladePerformance Wiper Blade by Pilot®. Pilot's Performance wiper blades are designed to provide maximum wiping ability for your import Car, Truck or SUV. These easy-to-attach blades fit like your original wipers, and have supple,...$11.00 - $15.80
- Pilot® GTR Wiper BladeGTR Wiper Blade by Pilot®. Pilot's Performance wiper blades are designed to provide maximum wiping ability for your Import Car, Truck or SUV. These easy-to-attach blades fit like your original wipers, and have supple, long-life,...$9.99
- Pilot® Arista Dual Wiper BladeArista Dual Wiper Blade by Pilot®. Sweep as much water as possible from your windshield at every pass with Pilot's dual wiper blade. These easy-to-attach blades fit like your original wipers, and have supple, long-life, natural...$9.99 - $14.20
- Bosch® Excel+™ Wiper BladeExcel+™ Wiper Blade by Bosch®. If you're looking for long-lasting, high performance wiper blades, Bosch Excel+ is your best choice. Thanks to the specially blended natural rubber compound, these wiper blades deliver the...$11.30 - $17.97
- Bosch® MicroEdge™ Wiper BladeMicroEdge™ Wiper Blade by Bosch®. Throw away your worn out wiper blades and install brand new MicroEdge wiper blades from Bosch for premium wiping performance in all weather conditions. Every blade uses specially blended natural...$9.23 - $13.64
- Related Magnum Pages
- Dodge Magnum Models
- Magnum R/T Wiper Blades
- Magnum SE Wiper Blades
- Magnum SRT8 Wiper Blades
- Magnum SXT Wiper Blades
- Magnum SXT Special Edition Wiper Blades
- Magnum XE Wiper Blades


text:
Lives in Tokyo, Japan
Works as a Electronic Engineer
Joined on Jan 26, 2009
Len_Gee: Does the MKII finally fixed the dust in lens issue that plagued the original GR?
Just get a 32mm filter/protector from ebay, it prevent dust from entering from the front of the lens.
I always put my GR mk1 in the dusty jean pocket, used over a year no dust in the lens.
Personally, I prefer using DLSR/ SLT, rather than the poor battery life, small e-mount camera.
The AF of my A77ii is still lots better than the A6000,
Interesting that Sony also admit that A6000's AF is only good enough for a holiday camera.
And A7Rii's AF is also not as fast as A6000, it is not surprise because Sony use hybrid AF, they use CDAF as the final state of the AF, APSC with small aperture zoom have wider DOF which help CDAF focus faster.
(Same reason Nikon 1 can CDAF faster becoz smaller sensor have wider DOF)
For large aperture zoom or long focal length telephoto lens, OSPDAF have difficulty to find focus at completely out-of-focus situation.
So DSLR / SLT is still better for sport shooter or demanding AF situation.
IMO, Sony should keep developing a-mount body with the unique SLT design.
It should have larger body, longer battery life, and ultimate AF ability.
"if we just did the same thing as Canon and Nikon we'd lose".
This was the statement that they told us, when they stopped making OVF camera.
SLT is a unique camera, it is something that Cankon does not have.
SLT combine the advantage of DSLR's level AF + EVF.
Everyone talking about A7Rii, because it have a new 42mp sensor, world first BIS Full Frame sensor, 4k video in FF, 5-axis IBIS, etc.
If they put this new sensor & technology in A99ii first, everyone will talk about it as well.
lhkjacky: IMO, Sony SLT design is the best,
It combine the advantage of both world,
DSLR's level AF at low light + the advantage of EVF.
It remove vibration from the mirror flip completely, at the same time it remain excellent AF tracking ability of DSLR.
I understand that some people may like a tiny camera like RX100.
But personally, the ergonomic grip & longer battery life is a plus not minus.
90% of sport shooter use 1Dx & D4s, unless Sony can make a mirrorless 300 F2.8, 500mm F4 small,
I don't think camera body size a problem for me.
But it is just my personal preference.
IMO, Sony SLT design is the best,
It combine the advantage of both world,
DSLR's level AF at low light + the advantage of EVF.
It remove vibration from the mirror flip completely, at the same time it remain excellent AF tracking ability of DSLR.
Surprise that they didn't add OSPDAF & image stabilization in GRII.
Anyway, I love my GR very much, not planning to upgrade any time soon.
Daniel4: I sold mine because it caught dust on the sensor twice, even though I carried it carefully in a plastic bag. If the GR II were dust sealed, I'd buy it again.
Ricoh GR does not have a front glass in front of the lens,
therefore when lens move, it suck in dust.
The problem can be solve easily, by adding a 32mm filter/protector in front of the lens.
You can easily find one for GR in ebay.
Mine put in jean pocket all the time never have problem. :-P
Roy LaFaver: Considering the IBIS and BSI in this camera, I don't see how we can even think about a list of cons. This will an amazing camera. The a7ii is plenty for me, but it is nice to see something like this beauty.
Poor battery life.
Tiny grip
Poor balance for heavy lens
Overheat during 4k video
No native F2.8 zoom lens
No dual card slots
Put it in A99 body, a-mount
higher burst rate 8fps / 10fps,
larger buffer, dual card slot,
Able to put 3 large batteries at once with vertical grip.
No overheat during 4k video
Then Sony you will take my money. :-)
captura: Much too big, and I don't need full-frame. When will Sony finally give us a NEX-7 upgrade camera?
The camera is too small, battery life is poor, only got single card slot, not support UHS-II
When will Sony finally give us a A99 upgrade camera?
Rooru S: DPR Team. Any comparisons between the AF performance of the A77M2 and the A6000 both with their respective 70-200 G lenses??
I guess the AF performance will be similar if there is enough light.
But when the light level drop, A6000 will start hunting,
while A77ii can still keep focus.
ESUELDO: I am using canon 70d with canon 300 mm f4 with tc for BF, I have sony a600 with 70-200 g and I liked both settings, I am wondering if I would buy the sony a77ii for wildlife, in that case with lens do you recommend , cost is important
I recommend Sony 70-400G2 or Tamron 150-600 for BOF
I had the 70-400G1 which is a great lens, now I am using Tamron 150-600.
The 70-400G2 will be AF faster & tracking better than G1
TxDad25: We've been using the SLT A57 since early 2013. We use it primarily to take photos of my son's basketball games. While we're generally happy, it does have some minor issues. That said, I'm pretty heavily invested into a-type lenses.
I'm ready (I think) to move to something more current. I'm curious if it makes sense to upgrade to something like the A77II, or to divest myself of the a mounts and move on to mirrorless. If I should upgrade in the DSLR space, is the A77II a significant enough improvement on the A57 to justify the cost? I've also considered jumping to Nikon, though I'm not sure if I'd gain anything there.
All thoughts or opinions are appreciated.
Lots of us were upgraded from A77mk1 to A77mk2.
And I can honestly tell you that it is a significant improvement compare to A77mk1 & it definitely worth the upgrade.
So, if you are upgrade from A57, I am sure you will be happier than us.
On Page 7.Operation & Controls -> Auto ISO
The MFNR you described is not correct.
In A77ii it does not just combining 3 frames of images.
The Mutli-Frame Noise reduction in A77ii have two setting,
With setting MFNR (High) it combine 12 frames of images.
while setting MFNR (Low) it combine 4 frames of images.
In old A77 Mk1, there was only one setting in MFNR,
which combine 6 frames of images.
You can check the "sequence length" value in EXIF data of the image
With the help of the faster processor Bionzx in A77ii, the MFNR processing time has been shorten a lots as well.
mgrum: I hate to say it again, but really what is the point of publishing a review a whole year after a camera is released? It's common elsewhere to have reviews written before a product hits the shelves. A year later and everyone who is seriously interested would either have bought it based on other reviews or decided to get something else.
It's a good job dpreview don't review films...
Although it is a little bit late.
But I think dpreview has done a good review.
They have tested & mention some good point, which is not included/tested in other review site.
PedroMZ: is it just me , the studio tests seem to show that the A77 produces noticeably softer images than the Canon and the A6000 even at low iso? I am puzzled by DP reviewer's comments that the images are very good at low iso,they certainly do not appear to be close to that of the above mentioned cameras. Just take a look at the Raws at iso 800. The A6000 beats it hands down. Either that or I need an optician's appointment.
They have explain it, it was the lens which made the difference.
Photoman: Would a A6000 w/70-200mm f4 G be a better sports combo than this?
A6000 is a nice camera, but not for indoor sport.
For A77ii, I use 70-200 2.8 most of the time and it focus great at in door. With 1 stop faster aperture, you get shallower DOF & lower noise.
For outdoor sport, I use 70-400G, or 150-600 for birding.
Which is not available in e-mount & it will be poor balance if use with adapter.
SnakePlissken: It's a superficial thing, but why are Sony DSLRs so ugly? I had an A700 and it was very smart looking. I think Canon makes the smartest, most ergonomic looking DSLRs, Nikon cameras are also immediately identifiable by their styling and red flash on the grip, Pentax K3 cameras look very elegant and well made too. In contrast, Sony's DLSRs in the last few years look like they have melted in the sun and are just too lumpen.
I am sure they are fine to use of course and for all the bashing that goes on here, as usual, the classic, legendary photographers of yore (other than large format photographers) would die for any of the digital cameras on the market today and I am sure would not care a jot about offset microlenses and the like that seem to consume people on DPReview.
I think different people have different sense of beauty
IMO, A77, A77II looks much much better than A700.
Just want to clarify, the MFNR in A77ii does not just average 3~4 frames.
The Mutli-Frame Noise reduction in A77ii have two setting,
With setting MFNR (High) it average 12 frames of images.
while setting MFNR (Low) it average 4 frames of images.
In old A77 Mk1, there is only one setting in MFNR,
which average 6 frames of images.
You can check the "sequence length" value in EXIF data of the image
With the help of the faster processor Bionzx in A77ii, the MFNR processing time has been shorten a lots as well.


text:
V.24 No.26 | 6/25/2015
Sonic ReducerThe Acorn Vieux Loup · Mail the Horse Planet Gates · Expert Alterations Expert Alterations EP
By Geoffrey Plant
This week we listened to The Acorn, Mail the Horse and Expert Alterations.
V.24 No.25 | 06/18/2015
Renee Chavez
Music was great, beer was good, and people were crazy
By Renee Chavez [ Sun Jun 21 2015 2:14 PM ]
"Someday you'll be looking back on your life/ At the memories, this is gonna be one of those nights". Yep, Grammy Award-winning Tim McGraw sums it up pretty darn well. The "Shotgun Rider Tour" made a stop at Isleta Amphitheater (5601 University Blvd. SE) on Friday night with Chase Bryant, Billy Currington and Tim McGraw and it was definitely one of those nights.
The sold out venue was packed with all manner of people, from rhinestone-bedazzled country girls straight out of a Shepler's catalogue to emo kids with weird hair--the buzzing crowd showed that country certainly ain't just for farm hands and mountain folk anymore.
Chase Bryant was up first at 7pm, looking like he just came from a preppy frat party but getting the crowd going with his hit single "Take It On Back". While still relatively new to the scene, the Nashville native is definitely one to watch and even made Rolling Stone Magazine's list of "10 Country Artists You Need to Know". Either way it looked like he was having a blast as he got the crowd standing and cranked away on a mustard-yellow Gibson Les Paul.
As anyone who has ever been to a concert knows, the time between sets is usually pretty boring and is only good for making a run to the beer tent. However, the speakers and giant screens kept the crowd entertained with ridiculously goofy ED and anti-depressant ad spoofs with Tim McGraw concerts as the "cure". I laughed, I cried, I sang.
As the temperature finally cooled down, the music got hotter with Billy Currington taking the stage and playing an energetic 13-song setlist that included hilarious "Pretty Good at Drinkin' Beer", sexy "Must Be Doin' Something Right" and a country version of "Uptown Funk" complete with coordinated moves from the band that had the crowd going wild. Repping his 6th album, Summer Forever, which was released last week, Currington more than fulfilled his duty in getting the crowd pumped.
Just as darkness fell over the sweating city, with a thundering intro and fans' ear-piercing screams even louder than the speakers, McGraw blasted into his set with the 1999 classic "Something Like That." "Truck Yeah" was up next amid the glow of thousands of smartphones being held up in the air. McGraw kept the energy high, bouncing between beloved older tunes like "Just to See You Smile" and newer favorites like "Diamond Rings and Old Barstools". Wearing his trademark black hat and tight jeans, he lived up to his title as a Country Music Icon and Top Male performer.
The encore was so awesome even Mother Nature cried with McGraw's first single from 1994, "Indian Outlaw", bringing on a dash of rain and some serious rain dancing. What a show! But if you missed it, don't worry--according to a recent interview, McGraw says he'll be working 'til he's 100 to keep the ladies in his family happy so he'll certainly make it back to Burque.
V.24 No.25 | 6/18/2015
Aural Fixation
A Life in Music
By August March
August March's anecdotes reveal what to expect if your life gets overly musical.
Sonic ReducerThe Beaumonts Hey Y'all, It's The Beaumonts · YOU Phase · Entourage Jazz Things Are Looking Up!
By Geoffrey Plant
This week we listened to YOU, The Beaumonts and Entourage Jazz
V.24 No.24 | 6/11/2015
By Geoffrey Plant
This week we listened to The Black Watch, The Copper Gamins and Little Wings.
V.19 No.30 | 7/29/2010
The Daily Word: in Harmonious Pizza
By Robert Maestas [ Wed Jun 10 2015 11:41 AM ]
honey, can you print me a pizza?
the wheels on the bus...are powered by WHAT?
the universe, or something like it
algorithmic nostaligia machine
pick a belief, any belief
the ancient wisdom of information technology
history as a two way mirror
the world as chorus, in harmony's tune
you probably shouldn't litter
V.24 No.23 | 6/4/2015
Sonic ReducerKidnapper Van Self · Wildewood The Other Side · Gabrielle Jackson Lotus
This week we listened to Gabrielle Jackson, Wildewood and Kidnapper Van.
V.24 No.22 | 5/28/2015
Aural Fixation
Kirk vs. Rock
A brief teleplay
By August March
The postmodern music rock layer indicates a mass extinction in the 21st century epoch.
Sonic ReducerHolly Herndon Platform · Graham Parker & The Rumour Mystery Glue · Twenty One Pilots Blurryface
By August March
This week we listened to Twenty One Pilots, Graham Parker & The Rumour and Holly Herndon.
V.24 No.21 | 5/21/2015
Sonic ReducerJoanna Gruesome Peanut Butter · Unknown Mortal Orchestra Multi-Love · Hot Chip Why Make Sense?
This week we listened to Joanna Gruesome, Unknown Mortal Orchestra and Hot Chip.
V.24 No.20 | 5/14/2015
Courtesy of artist
Music Magnified
Yellowcard Storms Sunshine
By Renee Chavez
Did Yellowcard rock Sunshine on Monday, May 4? Renee Chavez reports.
Sonic ReducerFaith No More Sol Invictus · Mumford & Sons Wilder Mind · Snoop Dogg Bush
By August March
This week we listened to new albums by Faith No More, Mumford & Sons and Snoop Dogg. Now with A/V!
Feature Interview
The People in Your Neighborhood
Interviews with ordinary Burqueños
By Renée Chavez
Our new column kicks off with a tattoo artist, a music teacher and a Doctor of Oriental Medicine.
V.24 No.19 | 05/07/2015
David Liebe Hart teleports into Sister tomorrow
By Samantha Anne Carrillo [ Tue May 12 2015 3:49 PM ]
Extraordinary weirdo David Liebe Hart brings his out-of-this-world electro to Sister on Wednesday night.
V.24 No.19 | 5/7/2015
Robert Maestas
Summer Guide 2015
Festival Guide
Summer fun across New Mexico
By Mark Lopez
A rundown of New Mexico's best summer events.
Tomorrow's Events
Suicidal Tendencies • thrash • Retox • Suspended • Rock Jong Il at Sunshine Theater
Outhouses: Underrated Icons of New Mexico History at Casa San Ysidro
6th Annual New Mexico Brew Fest at Expo New MexicoMore Recommended Events ››
home | feature | news | film | music | art | food | classifieds | personals | staff | lo-fi | search
© 1996-2015 Weekly Alibi email@example.com
View mobile version


text:
Craftsy Member since January 2012
I'm enrolled in these Craftsy classes:
Bag-Making Basics: Reversible Tote & Zipper Pouch
Craftsy Block of the Month 2012
Quick-Strip Paper Piecing
i am 86 and do pretty good on computer i orded a pattern and payed for it but cant download it can you help me firstname.lastname@example.com
Take Craftsy with you!
Craftsy Apps for iOS and Android. Read more »


text:
My Nonprofit Reviews
69 profile views
1 reviews
Review for Navy-Marine Corps Relief Society, Arlington, VA, USA
I have been volunteering for NMCRS for five years now and have loved every minute of it. The other volunteers who work here tirelessly give their time and efforts to help sailors in need and I have built a family working alongside them in every station we have been a part of. It's a wonderful charity!
More Feedback
Would you volunteer for this group again?
For the time you spent, how much of an impact did you feel your work or activity had?
Did the organization use your time wisely?
Very Well
Would you recommend this group to a friend?
When was your last experience with this nonprofit?
Role: Volunteer


text:
For Immediate Release: 1/11/2013
|Ride On Route Changes Begin Sunday
Beginning Sunday, January 13, the following changes will be made to Ride On bus routes to add service to new population centers and improve efficiencies. Daily service will be added to Park Potomac, a new residential and commercial area off Seven Locks and Montrose roads and I-270. The route 98 bus will expand to serve several areas, including the Cinnamon Woods neighborhood during peak periods, the Germantown Community Center during midday and the Maryland SoccerPlex on weekends. Service will be provided to a new area at Watkins Mill Road and MD 355 in Germantown and service within Olney will be restructured.
|Release ID: 13-013
Media Contact: Esther Bowring 240-777-6507
Return to News Releases


text:
Seven racegoers were taken to hospital after a loose horse jumped a boundary fence and galloped into a crowd of spectators during Australia's toughest steeplechase, the Grand Annual at the Warrnambool carnival in Victoria.
Having lost his jockey, the horse, Banna Strand, leapt an eight-foot fence and galloped among a section of the crowd in frightening scenes before escaping down a road which runs parallel to the course.
"You could hear the crowd, there were shrieks and yelling as the horse went over the fence," one eyewitness said. "Then the horse went down the street – there were people running everywhere."
Four of the injured were discharged after suffering minor injuries, but a two-year-old girl sustained a fractured collar bone and two other people were taken for precautionary x-rays.
Jumps racing is banned in all but two states in Australia and the incident, images of which were sent by witnesses to the Herald Sun, is sure to give extra impetus to protests against the sport, although it could have occurred in any type of race.
The Warrnambool May Carnival is Australia's premier regional racing festival, a three-day event of which the Grand Annual Steeplechase, run over nearly three and a half miles and over 33 jumps – more than even the Aintree Grand National – is the highlight.
The Racing Victoria chief executive, Rob Hines, said an inquiry into the incident was under way. "You take the precautions, you would have thought an eight-foot fence on the boundary of the course was sufficient," he said. "We will have to investigate, talking to the local council on whether that road should be closed to the general public in future."
Before the meeting had got under way on Tuesday, there had been protests at the track with calls for jumps racing to be withdrawn from the meeting. After the death of a horse on the first day of the meeting, Hugh Wirth, the president of the local branch of the RSPCA, described Warrnambool as "the killing fields". "[Jumps racing is] morally wrong – the community doesn't like it," he said. "The government is pandering to a minority group of people."


text:
- 800.878.7323
This item may be
Check for Availability
This title in other editions
Ice Cold: A Rizzoli & Isles Novelby Tess Gerritsen
Synopses & Reviews
Publisher Comments:
Chapter One
Plain of Angels, Idaho
She was the chosen one.
For months, he had been studying the girl, ever since she and her family had moved into the compound. Her father was George Sheldon, a mediocre carpenter who worked with the construction crew. Her mother, a bland and forgettable woman, was assigned to the communal bakery. Both had been unemployed and desperate when they'd first wandered into his church in Idaho Falls, seeking solace and salvation. Jeremiah had looked into their eyes, and he saw what he needed to see: lost souls in search of an anchor, any anchor.
They had been ripe for the harvest.
Now the Sheldons and their daughter, Katie, lived in Cottage C, in the newly built Calvary cluster. Every Sabbath, they sat in their assigned pew in the fourteenth row. In their front yard they'd planted hollyhocks and sunflowers, the same cheery plants that adorned all the other front gardens. In so many ways, they blended in with the other sixty-four families in The Gathering, families who labored together, worshiped together, and, every Sabbath evening, broke bread together.
But in one important way, the Sheldons were unique. They had an extraordinarily beautiful daughter. The daughter whom he could not stop staring at.
From his window, Jeremiah could see her in the school yard. It was noon recess, and students milled about outside, enjoying the warm September day, the boys in their white shirts and black pants, the girls in their long pastel dresses. They all looked healthy and sun-kissed, as children ought to look. Even among those swan-like girls, Katie Sheldon stood out, with her irrepressible curls and her bell-like laughter. How quickly girls change, he thought. In a single year, she had transformed from a child into a willowy young woman. Her bright eyes, gleaming hair, and rosy cheeks were all signs of fertility.
She stood among a trio of girls in the shade of a bur oak tree. Their heads were bent together like the Three Graces whispering secrets. Around them swirled the energy of the school yard, where students chattered and played hopscotch and kicked around a soccer ball.
Suddenly he noticed a boy crossing toward the three girls, and he frowned. The boy was about fifteen, with a thatch of blond hair and long legs that had already outgrown his trousers. Halfway across the yard, the boy paused, as though gathering up the courage to continue. Then his head lifted and he walked directly toward the girls. Toward Katie.
Jeremiah pressed closer to the window.
As the boy approached, Katie looked up and smiled. It was a sweet and innocent smile, directed at a classmate who almost certainly had only one thing on his mind. Oh yes, Jeremiah could guess what was in that boy's head. Sin. Filth. They were speaking now, Katie and the boy, as the other two girls knowingly slipped away. He could not hear their conversation through the noise of the school yard, but he saw the attentive tilt of Katie's head, the coquettish way she flicked her hair off her shoulder. He saw the boy lean in, as though sniffing and savoring her scent. Was that the McKinnon brat? Adam or Alan or something. There were so many families now living in the compound, and so many children, that he could not remember all their names. He glared down at the two of them, gripping the window frame so tightly that his nails dug into the paint.
He pi
Stranded with her traveling companions in an eerily deserted Wyoming village during a blizzard, Maura discovers that they are being watched and pursues help when a party member is injured, an effort that turns nightmarish when she is abducted into the woods. By the best-selling author of Harvest. 250,000 first printing.
New York Times bestselling author Tess Gerritsen's relentless, inventive novels take readers on pulse-racing thrill rides that are as satisfying as they are heart-stopping. Now, in this edge-of-your-seat suspense novel, a mysteriously isolated town stands abandoned as a silent watcher waits.
In Wyoming for a medical conference, Boston medical examiner Maura Isles joins a group of friends on a spur-of-the-moment ski trip. But when their SUV stalls on a snow-choked mountain road, they're stranded with no help in sight.
As night falls, the group seeks refuge from the blizzard in the remote village of Kingdom Come, where twelve eerily identical houses stand dark and abandoned. Something terrible has happened in Kingdom Come: Meals sit untouched on tables, cars are still parked in garages. The town's previous residents seem to have vanished into thin air, but footprints in the snow betray the presence of someone who still lurks in the cold darkness—someone who is watching Maura and her friends.
Days later, Boston homicide detective Jane Rizzoli receives the grim news that Maura's charred body has been found in a mountain ravine. Shocked and grieving, Jane is determined to learn what happened to her friend. The investigation plunges Jane into the twisted history of Kingdom Come, where a gruesome discovery lies buried beneath the snow. As horrifying revelations come to light, Jane closes in on an enemy both powerful and merciless—and the chilling truth about Maura's fate.
Published in the UK as THE KILLING PLACE.
About the Author
\Tess Gerritsen is a physician and an internationally bestselling author. She gained nationwide acclaim for her first novel of medical suspense, the New York Times bestseller Harvest. She is also the author of the bestsellers The Keepsake, The Bone Garden, The Mephisto Club, Vanish, Body Double, The Sinner, The Apprentice, The Surgeon, Life Support, Bloodstream, and Gravity. Tess Gerritsen lives in Maine.
What Our Readers Are Saying
Be the first to add a comment for a chance to win!
Product Details
Related Subjects
Fiction and Poetry » Mystery » A to Z


text:
In any discussion on cybersecurity, there's at least one elephant in the room: The U.S. faces serious threats to national security, and, despite warnings, seems to not be making much progress toward doing something about it.
Congress' failure to pass cybersecurity legislation this year was seen by many as a spectacular example of the government's inability to move beyond partisan bickering for the benefit of the country. More recently, the Defense Department has reportedly fallen behind on mandated plans for setting up oversight and streamlining acquisition of cyber capabilities.
Against a backdrop of constant cyber threat rhetoric, it would seem like the government has yet to take any real action on cybersecurity. There's no shortage of calls to action – so what's the holdup?
Insiders say there are a number of reasons. Among them:
At DOD, cyberspace is still a relatively new domain of warfare, which means there's a lot of ground to cover as U.S. Cyber Command, its service components and other cyber-focused organizations become fully operational.
Not everyone is a change agent
"The roles and responsibilities and overarching understanding are still evolving. You're talking about a lot of moving parts, with new command structure, new doctrine and a new rapid-response acquisition process – and trying to build that out to a functioning state that everyone understands," said former Army CIO/G6 Lt. Gen. Jeff Sorenson, now partner and vice president at A.T. Kearney. "They're still practicing on the football field. The actual execution is going to take a little time."
Along with the acquisition plans, DOD also is charged with establishing and implementing new cyber oversight; according to Defense News. Behind-the-scenes concerns about adding bureaucracy are another reason the plans are delayed. One former DOD official pointed out that's it's necessary to have the right kind of leadership in place to negotiate those complexities.
"There are more processes and bureaucracies in the government than ever before. The size of DOD has increased because of the Global War on Terror. There are more checks and balances than ever," said Gary Winkler, former Army Program Executive Officer–Enterprise Information Systems and now founder and CEO of Cyber Solutions. "Not everyone in the government is a change agent. Who is it going to be to work through the processes and bureaucracies? It's hard to find a champion to institute that kind of change."
Layers of bureaucracy
Unfortunately, that's an issue that goes far beyond the walls of the Pentagon. Across the government, layers of bureaucracy stand as a barrier between rhetoric and real action. It also contributes to a lack of true understanding of the cyber problem at hand, according to one cybersecurity expert.
"There is a lack of thought leadership," said Richard Bejtlich, chief security officer at Mandiant. "Cybersecurity is not like building a bridge, where all you have to worry about are weather, earthquakes and other things you can model for. Cybersecurity involves an intelligent adversary who will figure out a way to attack your bridge in a way you never considered."
Bejtlich noted that too often, officials from across government focus on the wrong goals – or worse, have no real goals at all – in cybersecurity, which contributes to the gridlock inhibiting real action.
"If you ask what the objective of a national cybersecurity plan may be, nobody has an explicit answer. There are a lot of plans for coming up with a standard and being rated against it, like FISMA, but it doesn't say anything about overall effect on security," Bejtlich said. "It's easier to say, 'Here's the standard, are you compliant?' But there's no one metric you can look at and say, 'Wow, this is getting worse every year.' There's no way to quantitatively measure risk. But in Washington, there's comfort with auditing against the standard."
That institutional approach often misses the mark on some of the most critical threats, hindering true progress in cybersecurity. It also sets up expectations that may be unreasonable or inaccurate, sources said.
"This is extraordinarily complex issue to deal with. The timeline by which [lawmakers] were expecting results – in some cases 180 days – that was probably a bit too far," Sorenson said.
While the lack of action is disconcerting and further incenses an American public fed up with partisan bickering, it doesn't necessarily mean national security is that much more threatened, sources suggested. Despite the legislative malaise, there is a flurry of action behind the scenes endeavoring to better secure U.S. interests in cyberspace.
"To say that we're at more risk because [the plans are delayed], I don't think is accurate. Every day people are working this issue, working to solve the vulnerabilities and working to make the network more hardened and capable. There is tremendous work being done on the inside that's not being publicized," Sorenson said.
About the Author
Amber Corrin is a former staff writer for FCW and Defense Systems.
E-Mail this page
Printable Format
Advanced Search
Meet 100 women and men who are doing great things in federal IT.
Click here for the full list
The outgoing speaker helped push forward data and transparency measures that have opened up the House of Representatives to the American people.
The Census Bureau announced plans to fold in new technology and third party data into its 2020 population count, but questions remain about the viability of the Bureau's enterprise IT.
A technology roadmap can help agencies reap the benefits FITARA has to offer. Here are the four stages of a successful effort.
In the newest Federal Employee Viewpoint Survey, feds show they're feeling better than they have over the past few years – but there's still room for improvement, especially in mission-critical IT.
The General Services Administration's Enterprise Infrastructure Solutions contract will anchor the agency's NS 2020 telecommunications strategy.
House and Senate both approve a measure to maintain funding at fiscal 2015 levels through Dec. 11.
The aviation regulator missed a Congressional deadline to develop rules of the sky-ways for drones.
Agency heads, acquisition officers and even CIOs don't need to be hard-core techies. FCW's four-part look at the expertise that's really required to make federal IT run.
FCW recognizes 14 individuals having an outsized impact early in their careers.
Might be posible that the Chinese would like to help us SOLVE some of our cybersecurity problems. They could be more interested in us giving our money to them legitimately, rather than watching us get ripped off by our own folks and endin' up too broke to buy more Made-in-China stuff ...... well, SOME of 'em maybe...
Humans do the cyber-attacking in all social spaces: federal gov't, local gov't, businesses, organizations. Some activity is criminal, some terrorism, some just "for fun". Counterfeiting and theft are also parts. This problem requires a strategic approach, not tactical ... and most gov't Leaders are tacticians as they got to the top by learning how to weave their careers thru the bureaucracy by not making waves, keeping their heads down, figuring out the best way to take that next career move, etc. They are inside-the-box organizational players, not outside-the-box thinkers: capable of looking at many different pieces and recognizing potential whole pictures. To thwart cyber attackers we need thinkers, not players.
What about cyber-usability? The Govt is also all-to-slow in adopting new, better, more-efficient, safer technology. Blackberry's are still the latest-greatest .. but only in the Govt.
Bascially because of "decision by committee" and useless bureaucracy the nation is at extreme risk. Great quotes from Government bureaucrats explaining how difficult is it to do anything. Maybe someone could visit China and see how they did it. They are prepared to Cyber attack at will, totally criple the nation....end of days senario here...planes falling out of the sky, no power, no water, train derailments, military ships floating dead in the water...but China will be totally protected from our counter attacks as they simply unplug from the internet and move to their self contained infrastructure.
The elephant in the room here is that behind every cyber attack is an attacker. There is a human element to cybersecurity that seems to be ignored with the focus exclusively on bits and bytes. Threats come from outside the enterprise and inside the enterprise and until the human risk elements are integrated into cybersecurity we can only have a partial solution at best.
Show All Comments
8609 Westwood Center Drive, Suite 500Vienna, VA 22182-2215 703-876-5100
© 1996-2013 1105 Media, Inc. All Rights Reserved. This copy is for your personal, non-commercial use only.To order presentation-ready copies for distribution to colleagues, clients or customers, visit: www.1105Reprints.com


text:
Critical TopicsAir Freight Management Customs Brokers Trade Compliance Global Trade Intermodal and Rail Freight Mobile & Wireless Motor Freight Management Ocean Freight Management Ports and Infrastructure Software & Technology Sustainability Third Party Logistics Transportation Management Systems Warehouse & Distribution Center Warehouse Management Systems All critical topics or View all topics
Latest Webcast
The excess transportation capacity during much of the recession enabled shippers to negotiate substantial reductions in transportation rates—ushering in a "cost savings addiction" that they now need to break. Attend this webcast to learn more about how carriers and shippers can collaborate to put an end to this epidemic.View more webcasts
Current news, information and trends in the commercial motor freight industry covering trucking, freight lines and carriers, logistics and classification.
Motor Freight Management ResourcesOptimizing Freight Procurement
Take Control of your Ocean Spend with Automated Freight Audit Solutions
Uncovering Hidden Costs and Unseen Impacts
Freight Management Today: More Freight, Fewer Trucks and Drivers
Collaborative Outsourcing® - Powerful New Ideas for Freight Management
Vitran completes acquisition of Milan's LTL operations
Posted 02/22 · 10:34 AM · LM EditorialMilan provides regional LTL services in the central and southern regions of the United States. By bringing Milan into the fold, Vitran gains 16 terminals in new markets, including Alabama, Georgia, Mississippi, North Carolina, and South Carolina.
Legislation for heavier trucks re-introduced in the House
Posted 02/21 · 01:19 PM · LM EditorialLegislation focused on increasing truck size and weights was reintroduced to Congress last week by Representatives Mike Michaud (D-Maine) and Jean Schmidt (R-Ohio).
News • Trucking • Transportation • Regulations •
Funding questions are front and center in proposed surface transportation bill
Posted 02/18 · 01:52 AM · LM EditorialOn the heels of President Obama's recently released proposed fiscal year 2012 budget request, there have been no shortages of opinions regarding the transportation components of the budget, most notably the proposed six-year, $556 billion surface transportation reauthorization proposal.
January retail sales numbers show continued gains, according to Commerce and NRF
Posted 02/15 · 09:58 AM · LM EditorialRetail sales began 2011 on a relatively promising note, according to data released by the United States Department of Commerce and the National Retail Federation (NRF). January retail sales, which include non-general merchandise like automobiles, gasoline, and restaurants, were $381.6 billion for a 0.3 percent increase from December and a 7.8 percent increase over January 2010, according to Commerce.
Diesel prices move up another 2.1 cents per gallon
Posted 02/15 · 07:45 AM · LM EditorialAnother week brought another increase in the price per gallon of diesel, with prices rising 2.1 cents this week to $3.534 per gallon, according to the Department of Energy's Energy Information Administration (EIA). On an annual basis, diesel prices are up 77.8 cents.
News • Trucking • Transportation • EIA • Diesel Prices • Diesel •
Proposed fiscal year 2012 budget represents increases for transportation funding
Posted 02/14 · 01:15 PM · LM EditorialFrom a supply chain and logistics perspective, the most interesting part of this budget is the proposed six-year, $556 billion surface transportation and reauthorization proposal.
TransCore data cites increased truckload freight availability in February
Posted 02/14 · 09:29 AM · LM EditorialIn 2010, easy annual comparisons to a troubled 2009 often paved the way for favorable data trends in the freight transportation sector. Based on recent data in TransCore's TrendLines report, those comparisons for the trucking sector are still heading in the right direction early into 2011.
News • Trucking • Truckload • Transportation • TransCore • Less-Than-Truckload •
WikiLeaks documents suggest Saudi Arabia is running out of oil
Posted 02/10 · 09:21 AM · LM EditorialDiplomat(s) expressed increasing concern that Saudi Arabia is no longer able to lift oil production at a rate fast enough to prevent oil prices from escalating.
Blogs • Sustainability • Trucking • Energy • Transportation •
BTS Freight Transportation Services Index up 1.5 percent in December
Posted 02/09 · 12:22 PM · LM EditorialThe Department of Transportation's Bureau of Transportation Statistics (BTS) reported today that its Freight Transportation Services Index (TSI) increased 1.5 percent in December, following a 0.3 percent decline in November.
Ceridian-UCLA Pulse of Commerce Index falls 0.3 percent in January
Posted 02/09 · 10:37 AM · LM EditorialFollowing an impressive 2.4 percent sequential gain in December, the January edition of the Ceridian-UCLA Pulse of Commerce Index (PCI) fell 0.3 percent in January, due, in part to harsh weather conditions throughout much of the United States.
News • Trucking • Transportation • Ceridian • UCLA • Pulse of Commerce Index •


text:
How to win at Pooh Sticks. Isn't it just a game of luck or is there any skill in playing the game? This age old question may have been answered once and for all.
Dr Rhys Morgan, from the Royal Academy of Engineering, has created a formula that helps to increase your chances of winning the classic game of Pooh Sticks..


text:
The Steppes4
Hemhill, Lumber Lane,, Hereford, HR1 4AL
Price FromView Rooms
- Excellent
- 35 guest reviews
"Stayed 2 nights mid week, nothing to complain about. Lovely room and en-suite, very comfortable. very clean, with all you would expect for y..."
"Our one night stay was great. Lovely room with beautiful blinds! Breakfast was good also. We will certainly book again when we take another..."
"Very welcoming and friendly. Nice pub nearby. Excellent breakfast...."
"Lin & Martin are very welcoming. Delightful room and everything spotlessly clean. Breakfast excellent. I would highly recommend a stay at th..."
About the hotel
Set in beautiful Herefordshire countryside yet only minutes from Hereford City centre, The Steppes Bed & Breakfast offers stylish accommodation with a hint of country. A taste of ancient English history at its best, yet with the luxury you would expect from a top rate bed and breakfast establishment. An historical building in its own right, The Steppes is said to date back to the 16th Century when Henry VIII was King of England and England was torn by the Restoration.
Although we are located in the heart of some very pretty Herefordshire countryside, we have adapted our facilities to enable everyone to enjoy the location. There are four delightful ensuite rooms, contained within an extension and annexe to the house, offering the highest standards of comfort. Full accessability is provided to three rooms and there is a flight of stairs to the fourth. As mentioned above, The Steppes dates back to 1530, and today is a happy home for Lin and Martin. Lin is a keen advocate for self-sufficiency and as such has a large vegetable plot stocked with supplies for the year, plus chickens, sheep and bees. If the bees have been busy this year, there will be honey available for sale – just ask Lin for details. Breakfast eggs are supplied courtesy of Lin's chickens and all ingredients are sourced from local Hereford suppliers where possible. Each room has been lavishly furnished with the latest designs and equipped with crisp white bed linen and fluffy white towels, free WiFi, Freeview colour TVs, tea and coffee making facilities and fridge. Large windows look out to the gardens and pond, offering pleasant views at any time of the year. We have one king suite with lounge area, two king en suite rooms, and one twin room. Walkers and cyclists are welcome. Lin and Martin, your hosts, are both keen to bring you an experience you will want to repeat, whether you are on holiday or on a business trip. They will assist with local knowledge
Read MoreLess
Room Availability
Showing Tuesday 13 October 2015 to Wednesday 14 October 2015Change Search
Facilities Show/hide
- Parking
- Car parking available onsite
- Business
- Wi-Fi Available In Public Areas
Useful Info Show/hide
- From 16:30 hours
- Until 10:30 hours
- The price shown is based on the occupancy and dates you have searched for. Prices and availability are subject to change based on the arrival date, number of nights and occupancy searched for. All prices are inclusive of all local taxes.
- Pets are not allowed
Customer Reviews
Our reviews are from genuine LateRooms.com customers. We verify that the customer has stayed before leaving a review.
100% would recommend it to a friend
Customer service
Food quality
Room quality
wonderful stay your stay.
Stayed 2 nights mid week, nothing to complain about.
Lovely room and en-suite, very comfortable. very clean, with all you would expect for your stay. Lin and Martin great hosts. Would stay again
Read More Less
Excellent Accomodation
Our one night stay was great.
Lovely room with beautiful blinds. Breakfast was good also. We will certainly book again when we take another trip to the area.
Read More Less


text:
why is there no more talk of a new star trek tv series?
View Single Post
April 16 2013, 09:57 AM
Shaka Zulu
Fleet Captain
Location: Bulawayo Military Krral
Re: why is there no more talk of a new star trek tv series?
Ryan8bit wrote:
Except anime doesn't really classify as the uncanny valley.
That much
know; it seems that most people in North America don't know that, conditioned as they are to believe that the style of Pixar and contemporaries is the only style to animate something in.
Also, film/tv professionals don't use DAZ studios because it's generally shitty.
Yes, I can see that, but for Tim Vining, it was all that he had (and the rub is, it works better for
Star Trek
, because it at least
realistic and is close enough to
for it to become the success for most of the people that have seen it.)
Shaka Zulu
View Public Profile
Send a private message to Shaka Zulu
Find More Posts by Shaka Zulu


text:
Difference between a "Gun Belt" and a Dickies belt from Wal-Mart
Discussion in 'Carry Issues' started by wrangler_dave9, Jun 15, 2012.
Page 2 of 4
|Similar Threads
|Difference between Mag Gens and their compatability?
|General Glocking
|Sep 19, 2015
|Whats the difference between a Beretta G and a Beretta FS
|The Okie Corral
|Aug 25, 2015
|What is the difference between a democrat and a socialist?
|Political Issues
|Jul 31, 2015
|Difference between "west german" and "german" sigs
|General Firearms Forum
|Jul 16, 2015
|Only Difference Between Dylann Roof and Bill Ayers Is Legitimacy Among the Left
|Political Issues
|Jun 22, 2015