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text:
LupelloSlay Lupello.
|Lupello slain
DescriptionI've been thinking... the wolves might stop attacking if we kill their pack leader.
We call him Lupello, and he patrols the opposite riverbank.
<Francis' concentration is broken by another attack. Perhaps you should go deal with Lupello yourself.>
I know I should be the one fighting them off. Maybe I'm not cut out for shepherding after all.
RewardsYou will receive: 10 20
GainsUpon completion of this quest you will gain:
- 13,140 experience

subset: commoncrawl


text:
Our Herbal Shampoo supports regeneration and blood ciruculation to your skin and hair roots leaving your hair healthy, shiny and silky soft.
Formulated with Dr. Alkaitis' signature Hair & Scalp Herbal Complex this shampoo restores balance and is beneficial to all hair types. Gentle enough to use daily.
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P.S. K811 Connie Lekas School
2525 HARING STREET, BROOKLYN, NY 11235Phone: 718-769-6984
School Name, Number, or Address
Advanced Search
Our Mission
The Connie Lekas School, P. 811K is a multi-culture, multi-ethnic school that is committed to inspiring, guiding, and supporting its students and parents. The P811K staff work collaboratively in a respectful and nurturing environment to develop quality educational programs for all our students. Our core mission is to provide an educational environment that will enable all students to develop to their fullest potential through high performance standards. Using a team approach, parents, students and staff share common goals and open communication which enables the school to maintain a program that enhances the lives of our students and encourages a welcoming and safe environment. It is our belief that through these efforts the highest individual achievements will result in the development of capable, confident and contributing citizens for the 21st century.
· The mission of P811K is to provide an educational environment that will enable all students to develop their fullest potential in an academic literacy based program with an emphasis on Activities for Daily Living with strong behavioral supports.· Students learn best when the subject matter is meaningful and the instruction is interesting.· Staff and parents need to be provided with professional development opportunities to enhance their role as life-long learners.· Every student can learn and deserves a skilled, component and compassionate school community (staff and parent) who has a commitment to life-long learning.· Students have meaningful ways to contribute to the community.· Through a team approach, parents, students and staff share common goals and open communication that enables us to maintain a program that enhances the lives of our students and encourages a welcome and safe environment to staff, students and parents.· Parents are equal partners in the education of their children and are welcomed into the school as full active participants.· Responsible and respectful behavior is an internal environment that needs to be encouraged and reinforced (i.e., dress, speaking to each other and students).· All special efforts are recognized. Open communication is the best way to solve problems.· All staff need to fulfill their responsibilities in a safe and secure environment.· All staff shares equally in the success of all students.
Special Programs
-Applied Behavior -Bilingual -ESL -Inclusion-Industrial Arts -Job Development -Literacy -Parent Education & Support Groups-Project M.O.V.E. -Related Services -School-to-Work -Sports-Technology -Theater Arts -Transition -Universal Design for Learning


text:
Lexus is a luxury brand created by Toyota that offers a complete line of cars, trucks and hybrid vehicles. Their reputation has been built on solid, reliable and luxuriously-appointed vehicles, although some criticism concerns their lack of pure driving involvement. [...]
The vehicle line-up expanded with the addition of the GS 300 sedan in 1993 and the LX 450 full-size SUV in 1995, an upscale Land Cruiser. Two years later, the GS got a redesign and added a GS 400 variant. In 1998, the RX 300 mid-size crossover was introduced and quickly became a sales success, while the LX was renamed LX 470 due to an engine displacement increase.
Before the turn of the century, the compact-sized IS 300 sedan was launched, which also spawned the SportCross wagon for a few years, and in 2001, the SC coupes were replaced with the SC 430, a V8-powered roadster featuring a power-folding hard top. The flagship LS became the LS 430 that same year, while the GX 470 appeared for the 2003 model year.
Receiving a bigger V6 engine, the ES 300 became the ES 330 in 2004, the same year Toyota's Cambridge, Ontario plant started assembling the RX 330, now in its second generation. Lexus introduced its first hybrid model for 2005 as the RX 400h, and in 2006, a new IS was introduced as the IS 250 and IS 350, eventually adding a convertible version.
During the GS sedan's 3rd-generation cycle, engine displacements were increased and variants included the GS 300, GS 350, GS 430 and GS 460. A hybrid version also joined the line-up for the 2007 model year. The LS was renamed LS 460, adding long-wheelbase, all-wheel drive and hybrid versions in the process. In 2008, the LX got a redesign and a designation change to LX 570.
Today's Lexus product range includes the compact CT 200h hybrid hatchback, the IS sedan and convertible, the HS 250h hybrid sedan, the mid-size ES and GS sedans, the GS 450h hybrid, the full-size LS and LS 600h L hybrid, the RX and RX 450h hybrid mid-size crossovers, the GX and LX SUVs as well as the 552-horsepower LFA supercar, of which only 10 were offered in Canada.
Discontinued Lexus models
2015 Lexus RC F Review
Most of you want a car that'll make others jealous. A Lexus sports car (with the except...
2016 Lexus RX First Drive
As a pioneer of the luxo CUV segment, the RX has to impress (and it does) for 2016.
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Remember that girl in high school? The one who was ridiculously attractive, even before...
Hydrogen-powered Lexus LS prepares for Tokyo Auto Show
The Lexus LS Fuel Cell Vehicle concept will make its global debut at the upcoming Tokyo Auto Show and could hit the market around 2018.
Lexus Hoverboard successfully completes test phase (video)
The company held its final tests in Barcelona, and we have footage you don't want to miss!
New 2016 Lexus ES 300h offers more luxury to North American customers
Lexus has just revealed the 2016 ES 300h sedan, which offers bold new looks and more luxury features. It will go on sale in North America in a few months.


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David Banks Getty Images
They were already starting to think it was the "same old Jay" on Sunday at Soldier Field when he threw a fourth-quarter interception that the Oakland Raiders turned into a go-ahead field goal against Cutler's Chicago Bears.But, despite the after-effects of a hamstring injury that kept him out of a game last week, Cutler instead played the hero instead of the goat. He drove the Bears 48 yards in the last two minutes, Robbie Gould kicked his third field goal of the game, a 49-yarder with two seconds remaining, and the Bears beat the Raiders, 22-20, for their first victory of the season.Cutler deferred credit to a jury-rigged offensive line, juggled because of injuries, but the difference in the game was the patience he showed — maybe because the hamstring forced him to — in completing 28 of 43 passes, including 5 of 8 on the winning drive."There were a lot of moving parts up there, and those guys held their own," said Cutler, who acknowledged that he was limited "a little bit" physically by the hamstring and deliberately kept himself from trying to scramble out of the pocket."He's a tough son of a bug," Chicago coach John Fox said of his quarterback. "He's got an injury that some lesser guys might not have been out there."Chicago started the game with a backup replacing injured left tackle Jermon Bushrod and then had to juggle further when center Will Montgomery suffered an apparent broken leg on the third play from scrimmage. As a result, left guard Matt Slauson slid into the center spot and that may have been at least partially responsible for a fumbled snap that led to an Oakland touchdown.But staying in the pocket may prove the best strategy for Cutler, even when his hamstring is fully healthy, because it reduces the margin for error.Instead, it appeared it was the Raiders who made the most grievous error by settling for a field goal with 2:05 remaining to take a 20-19 lead and effect the sixth lead change of the game, rather than play aggressively for a touchdown that might have made a Chicago comeback more difficult.After they got to the Bears' 33-yard line with more than four minutes remaining, Oakland did not throw another pass, instead calling four consecutive running plays before Sebastian Janikowski kicked a 41-yard field goal."They were pretty conservative," Cutler said.Oakland coach Jack Del Rio defended the play calling, saying, "I think we felt like we were moving it pretty good and thought we had a better shot to move the sticks on that third-and-two."One problem for the Raiders was that, by that point in the game, Del Rio already had benched his leading rusher, Latavius Murray, because of a lost fumble and two dropped passes, one of which Murray bounced into an interception.After the Janikowski kick, the Bears kick-started their winning drive with Cutler's fourth down completion to tight end Martellus Bennett, who caught 11 passes, second highest total of his career, for 83 yards.With the Bears essentially conceding the sideline passes to Cutler — allowing not only completions but clock stappages — the Bears had plenty of time to work downfield. Cutler found Matt Forte for seven yards and then Marquess Wilson for six on 3rd-and-3. After a downfield shot fell incomplete, Eddie Royal made a nifty sideline catch for 12 yards and then Wilson, who earlier on the drive dropped a pass, made a fingertip grab for nine.That was pretty much all Chicago needed and, after running Forte into the line for two, the Bears called on Gould — who, to that point had been the difference in the game due to a blocked extra point.Gould, whose other field goals were from 19 and 54 yards, nailed the winning kick with plenty to spare."It was awesome when we were celebrating with two seconds left on the clock," Gould said. "Those are the type of wins you want to see, and usually, those type of wins catapult a team and give them a lot of confidence for the next week."There were "a couple of areas that will stand out," Del Rio said, and the most that gnawed on him most clearly was his team's third-down defense. The Bears, who had converted only 16 of 42 third downs into first downs in their three losses, were 10 for 17 in this game."They played well, and we didn't play as well as we're capable of," Del Rio said. "These things happen. They get paid, too."NOTES: QB Jay Cutler returned to the lineup after missing one game but the Bears played without three injured regulars including No. 1 wideout Alshon Jeffery. Also missing were OLT Jermon Bushrod and NT Jeremiah Ratliff. … The Bears lost C Will Montgomery with an ankle injury on the third play of the game, causing shuffling on the line. LG Matt Slauson moved to center and Patrick Omameh went in at left guard. … Oakland WR Michael Crabtree left the game with an ankle injury in the second quarter but returned. … Bears FS Antrell Rolle was injured (ankle) on the first play of the third quarter and did not return.
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His profile rose again, for the wrong reasons, thanks to a November 2010 DUI arrest in Florida.
Former "Partridge Family" star David Cassidy has been charged by authorities in Florida with leaving the scene of a traffic accident last month.
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Vt. school closes over mass illnessMarch 08,2013Vt. school closes
over mass illness
BRIDPORT The Vermont Health Department is investigating conditions at a school in Bridport after about 80 of the 130 students and staff either called in or went home sick.
The illnesses were reported Wednesday at the Bridport Central School. The district has called off school for Thursday and Friday as it sanitizes the building.
The Health Department is testing samples from those who are sick.
Symptoms included diarrhea and vomiting. Infectious disease epidemiologist Bradley Tompkins said it could be the Norovirus, also known as stomach flu.
Students in preschool through sixth grade attend the school.MORE IN This Just InMONTPELIER The states highest court has upheld a jury conviction for a Lyndon man charged with... Full StoryST. ALBANS The American Red Cross says it responded to a house fire in St. Full StoryBERLIN- Officials say a school bus was hit by a truck and overturned in Berlin, shortly after... Full Story
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Merino wool meets hi-tech with the Outdoor Research Biosensor Liners. The Biosensor is a naturally wicking, naturally anti-odor and touch-screen-friendly thermal merino wool liner glove...Continue Reading
Merino wool meets hi-tech with the Outdoor Research Biosensor Liners. The Biosensor is a naturally wicking, naturally anti-odor and touch-screen-friendly thermal merino wool liner glove...Continue Reading
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VA has added a blue button to allow veterans to download their own records
Federal officials and private-sector partners are promoting "blue button" applications that would allow patients to securely download their personal health information from a provider's or insurer's record system.
On Aug. 29, the Veterans Affairs Department introduced such a capability in beta form on its My HealtheVet online application so veterans can access their health data. VA and the Centers for Medicare and Medicaid Services are scheduled to officially launch blue-button programs in early October. The programs were developed in collaboration with the Defense Department and the Markle Foundation's Consumer Engagement Workgroup.
In addition, Markle was one of 46 organizations that asked the Obama administration to include the download capabilities as a requirement for provider-operated and personal electronic health record systems.
ONCHIT tests guidance for health records
The White House and Congress are distributing $20 billion in health information technology incentives through the economic stimulus law. Most of that money will go to doctors and hospitals that install EHR systems for the first time.
On Aug. 31, Markle released a policy paper recommending that the blue-button download capability be a priority in the nationwide push to adopt health IT. The paper includes specific privacy and security practices for the downloads.
Supporting the Markle recommendations are technology companies and organizations that represent providers, consumers, insurers and privacy advocates.
"This capability is not common today, but we have the opportunity to make it a basic expectation, especially now that billions of public dollars will be flowing to help subsidize health information technology," said Carol Diamond, managing director of Markle's health care initiatives, in a news release.
The foundation also announced a Blue Button Challenge to encourage computer programmers and developers to create Web-based applications to help people stay healthy.
About the Author
Alice Lipowicz is a staff writer covering government 2.0, homeland security and other IT policies for Federal Computer Week.
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The General Services Administration's Enterprise Infrastructure Solutions contract will anchor the agency's NS 2020 telecommunications strategy.
House and Senate both approve a measure to maintain funding at fiscal 2015 levels through Dec. 11.
The aviation regulator missed a Congressional deadline to develop rules of the sky-ways for drones.
Agency heads, acquisition officers and even CIOs don't need to be hard-core techies. FCW's four-part look at the expertise that's really required to make federal IT run.
FCW recognizes 14 individuals having an outsized impact early in their careers.
As Steve Kelman returns from a summer of aggressive medical treatment, he considers the all-too-common aversion to short-term sacrifices.
Massive open online courses can offer specialized IT instruction on a flexible schedule and on the cheap. That may not always mesh with government's preference for structure and certification, however.
The federal government craves more cybersecurity professionals. These six schools are helping meet that demand.
Former ACT president will take a job with Gartner, follow his spouse to Vienna, Austria.
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Sony unveils Batman: Arkham Knight limited-edition PS4 and more
Sony made a new limited-edition PlayStation 4. It's a Batman: Arkham Knight-themed version. In an attempt to lure gamers who are waiting for the final installment of Rocksteady Studio's Batman Arkham series, Sony has announced a new PlayStation 4 design... >>
Sony PS4 sales exceed 20 million, and Nielsen says it's due to resolution
Sony wants you to know that its PlayStation 4 gaming console is doing really, really well. While at the Game Developers Conference, the company announced that worldwide PlayStation 4 sales have exceeded 20.2 million as of 1 March, meaning more than 1.7... >>
HBO Go app finally arrives for PS4 after year-long delay
You can now use a PlayStation 4 to watch your favourite HBO shows. Sony has announced the HBO Go app for PS4 is now available for download, and that the app works just like the PS3 version. You must first authenticate your console with your cable/satellite... >>
PlayStation 4 review: One year on, it's the choice console for gamers
One year after its initial release, and to cap off two decades of PlayStation, the Sony PlayStation 4 finds itself in an esteemed position at the tail-end of 2014. The PS4 seems to be winning the new-generation console race against the Xbox One - at least,... >>
Sky Go on PS4: Sony console starts home entertainment pitch in earnest
Sky has announced that Sky Go customers will be able to access the catch-up service on the Sony PlayStation 4 from today via the TV from Sky app in PlayStation Store. However, users will have to pay extra for the feature unless they already subscribe... >>
LittleBigPlanet 3 review: Dapper new threads
In a year when gaming has revolved around shooting aliens, shanking zombies, and slaying dragons, there's something wonderfully refreshing about playing a knitted Sackperson and running around inside the imagination. Or, as is the case in LittleBigPlanet... >>
Sony Xperia Z3 series offers PS4 Remote Play, GCM10 lets you mount a DualShock controller
With a complete refresh of flagship, compact and tablets, the new Xperia Z3 family of device may well be of biggest appeal to PlayStation 4 owners. Why? Because these devices offer PS4 Remote Play. Like the PS Vita, you'll be able to use your Z3 device... >>
Bungie's Destiny Beta now open to everyone, including those who didn't pre-order
Those who didn't pre-order the video game Destiny will still be able to play the official beta tonight. Bungie has announced it will open the beta to everyone across the world, as it prepares for the launch of Destiny this autumn. "Today, at 4:00 PM PDT,... >>
Microsoft previews Xbox One August update, will support mobile purchasing
Microsoft has detailed what you can expect in the next Xbox One update coming in August. Larry Hyrb, the head of Xbox Live who is widely known by his gamertage Major Nelson, published a blog post and video on Friday to explain what the update will bring.... >>
Destiny Beta now live for PS4 and PS3, with Destiny Companion app for mobile and web
Anyone who pre-ordered the video game Destiny can now play the official beta that just released for PlayStation 4 and PlayStation 3 consoles. Destiny is a highly anticipated role-playing, first-person shooter video game that features a "mythic science-fiction"... >>


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Find Events
Scientific Injection Molding (Fall 2013 Course)
September 21-28, 2013
Pomona , California - United States
Cal Poly Pomona Extended University Cal Poly Pomona, CTTi (Bldg. 220A, Rm 104)
3605 W Temple Ave Pomona ,CA 91768
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Registration Deadline:
September 20, 2013
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Technical seminar
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Rebecca Pang
Event Detail:
The course emphasis is on scientific approach to a somewhat complex injection molding process in order to simplify and eliminate basic misunderstanding about processing techniques employed today throughout the industry. Students will learn the importance of understanding polymer basics, material flow properties, viscosity-shear rate curve, major plastics variables in molding, decoupled molding techniques, data analysis and interpretation. The course will cover fundamental and scientific approaches to material drying, venting, cooling, use of regrind, how to prepare universal set-up sheet, cycle time optimization, tooling considerations, etc. Use of modern tools and techniques such as mold flow analysis, cavity pressure transducers, and data acquisition tools along with troubleshooting techniques will also be covered.
Course content:
Polymer Basics, Plastics Materials and Flow Characteristics
Part Design Fundamentals
Overview of Basic Injection Molding Process
Drying, Material Mixing, Coloring, Regrind Usage
Major Process Variables
Decoupled Molding, Universal Set Up Sheet
Tooling Considerations, Venting, Cooling, Ejection
Cycle Time Optimization and Troubleshooting Techniques
Mold Flow Analysis
Tricks to Improve Productivity
Modern Injection Molding Operation
Non-Credit Courses with Three or Fewer Class Meetings*
A full refund will be issued if the refund request is received by the College of the Extended University prior to the first class meeting. No refunds will be issued after the start of the first class meeting.
A full refund will be issued for cancelled classes.
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My Nonprofit Reviews
Review for Northend Jewish School, Seattle, WA, USA
Over four years ago I was a student at this school. The three years I learned at this school were something remarkable. Not only did I learn about Judaism and general knowledge (math, reading, etc.), but I learned that you need to be against fighting and that there is always a peaceful way to resolve a conflict. During my time we were at the old building adjacent to the synagogue, but they're now at the new building, which, sadly, I wasn't able to learn at. Nevertheless, I visited the school at the new building about three and a half years ago and it is still the remarkable place that I remember. Today we need these type of school, and being in different places across the planet, I really know. Long live SJCS!!
More Feedback
What I've enjoyed the most about my experience with this nonprofit is...
- Tikun olam (making the world a better place) - Intuitive teaching methods - We would celebrate the Jewish and Israeli holiday by "flying" to Israel, Passover seder w/whole school, "fly to Israel", etc.) - Caring, positive attitude & being optimistic
The kinds of staff and volunteers that I met were...
Talented, kind, wise, and friendly. 100% in any case. Everyone was there to help no matter what.
If this organization had 10 million bucks, it could...
Make the teaching methods better (P.E., playground, etc.)
Ways to make it better...
I had a better P.E. class and dance class
In my opinion, the biggest challenges facing this organization are...
Getting kids to come
One thing I'd also say is that...
This school is something extraordinary - no doubt about it. The things that I wrote could be better, I think.
How frequently have you been involved with the organization?
One time
When was your last experience with this nonprofit?


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Hillary Clinton
Hillary Clinton News
News about Hillary Clinton continually updated from thousands of sources around the net.
Sanders says some GOPers are feeling the Bern
16 hrs ago | KION 46 | Comment?
Speaker-in-waiting spent years cultivating GOP lawmakers
17 hrs ago | SouthCoastToday.com | Comment?
Periods do rule your life: Author reveals the right time on your...
21 hrs ago | Daily Mail | Comment?
Clinton's quotes favoring Pacific trade pact she now opposes
Yesterday | Worcester Telegram ... | Comment?
House OKs special panel for Planned Parenthood inquiry
Wednesday | Star-Telegram.com | Comment?
American Terrorism: Plain and Simple
terrorism 1,258
Tragic: 30 Stars Who Died Shockingly Young From AIDS
Iran Nuclear Agreement: Black Mark or Gold Star for Obama?
policy 1,524
House blocks attempt to end Benghazi panel
Wednesday | WTAE-TV Pittsburgh | Comment?
Boehner booked to visit Jimmy Fallon
Wednesday | Denver Post | Comment?
Lincoln Chafee visits FOX Business Network at FOX Studios
Wednesday | The Star Press | Comment?
Jay Leno returns to 'The Tonight Show'
Wednesday | Olney Enterprise | Comment?
State Department seeks more work-related emails from Clinton
Wednesday | Greenwich Citizen | Comment?
Trump, Clinton lead swing state poll
Wednesday | CNN | Comment?
Democratic senators to Biden: Gloves will come off
Wednesday | KMIZ | Comment?
5 times Clinton broke from Obama
Tuesday | Click Orlando | Comment?
Fiorina takes on the Washington Post
Tuesday | KCRA-TV Sacramento | 27
The election that could kill TPP trade deal: No, not the Canadian one
Tuesday | Brandon Sun | Comment?
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Gov's revenue plan: Income tax up, sales tax down - 70 Comments
Gov. Deval Patrick announced an income tax increase of 19 percent but a sales tax cut of 28 percent tonight during his State of the Commonwealth address tonight.
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I'd like to use this for a shop program that is built on multisite, where the folks register using a gravity form and have a profile that they can update, etc - all on the front end, with no backend access. Ideally, I'd like to have my users put their ZIP code in during the time when they're setting up their online store, and then show up in the listings. Is this possible using your plugin? I like what I see here!
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i am a huge fan of Dr. Passer. The best at figuring out problems and applying effective treatment.
GREAT DOCTOR! When dealing with such emotionally charged,highly complex,and seriously stressful issues as addiction and recovery, it is impera... Read more
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Needs to engage more and spend time with his patients.
Arrogant, egotistical, and unwilling to listen. Drew his own conclusions without hearing details from me.
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To quote the late Yogi Berra, it must feel like déjà vu all over again for the Food and Drug Administration (FDA) (or, if you prefer, Crosby, Stills, Nash & Young's song, "Déjà Vu" ("We have all been here before")). Fresh off...more
The Free Speech Clause of the First Amendment prevailed in the latest challenge to the FDA's prohibition against marketing FDA-approved drugs for off-label (or non-FDA-approved) uses. Applying the Second Circuit's...more
Friday's ruling in Amarin Pharma, Inc. v. United States Food & Drug Administration is a monumental event. It signals the dawn of a new era for prescription drug promotion....more
On August 7, Citing the First Amendment, a Southern District of New York court ruled that FDA cannot limit a manufacturer's "truthful and non-misleading speech promoting off-label use" of a drug and evaluated specific...more
The last couple of times we've commented on new law review articles, we haven't liked what we've seen very much. We're gluttons for punishment, however, and this time we were rewarded. We found a couple of recent law review...more
It is a very common practice. Drug sales reps visit a client, usually a hospital, a clinic or a doctor, with the sole purpose of selling a drug or medical device. That is the primary way a doctor learns about a drug or...more
In This Issue:
- Can Experts Testify as to the Ethics or State of Mind of Corporate Defendants?
- Patent Reform for Biotech Companies
- United States v. Caronia and its Implications for Off-Label...more
Following the Second Circuit's marquee First Amendment ruling in the Caronia case, two recent developments demonstrate a shift in the battleground for First Amendment challenges to the prohibition on off-label promotion under...more
On March 4, 2013, a panel of the United States Court of Appeals for the Ninth Circuit issued its opinion in United States v. Harkonen,1 a case in which the CEO of a pharmaceutical company was prosecuted for transmitting...more
In This Issue:
- New HIPAA "Megarule" Broadens Enforcement
- Government Declines to Seek Rehearing of Landmark Off-Label Speech Decision
- Seizure of Rothstein Ponzi Assets Highlights Tension Between...more
After two years of deliberation, the U.S. Second Circuit Court of Appeals has finally issued its decision in United States v. Caronia, holding that the government cannot prosecute pharmaceutical manufacturers or their...more
On December 3, 2012, the United States Court of Appeals for the Second Circuit held that the First Amendment protects pharmaceutical companies who truthfully promote the lawful, off-label use of prescription drugs from...more
In October 2009, we published the first edition of this White Paper, focusing primarily on social media issues in the United States. The response was overwhelming and far beyond our expectation — clients, friends, press and...more
On December 3, 2012, a panel of three judges on the U.S. Court of Appeals for the Second Circuit overturned the November 2009 conviction of Alfred Caronia for conspiracy to introduce a misbranded drug into interstate commerce...more
In a long-awaited decision, on December 3, 2012, a divided panel (2–1) of the U.S. Court of Appeals for the Second Circuit vacated the conviction of Alfred Caronia, a former pharmaceutical sales representative for Jazz...more
The Second Circuit's December 3, 2012 decision in United States v. Caronia, No. 09-5006-CR, could cause a sea change in the growing number of prosecutions brought by the government to prevent the off-label promotion of drugs...more
Last week a federal appeals court made a ruling that chips away at a fundamental aspect of the FDA's gatekeeping function with new drugs. The court tossed a conviction of a drug sales representative who was promoting drugs...more
On December 3, 2012, the United States Court of Appeals for the Second Circuit issued an opinion that stands to transform the regulatory landscape in which pharmaceutical and medical device companies operate. In recent...more
In a significant blow to the U.S. government's enforcement efforts against the pharmaceutical industry, a panel of the Second Circuit overturned the conviction of a pharmaceutical sales representative for conspiracy to...more
In a much-anticipated decision, a federal court of appeals has ruled that the government cannot criminally prosecute pharmaceutical manufacturers and their representatives under the Food, Drug and Cosmetics Act ("FDCA") for...more
The U.S. Court of Appeals for the 2nd Circuit upheld a First Amendment challenge to the federal prosecution of pharmaceutical salesperson Alfred Caronia for off-label marketing, http://www.ca2.uscourts.gov/decisions. Given...more
A recent decision by the U.S. Court of Appeals for the Second Circuit may significantly curtail enforcement efforts relating to the so-called "off-label" use of drugs approved by the Food and Drug Administration for specific...more
The US Court of Appeals for the Second Circuit, in a decision issued on December 3, 2012, in United States v. Caronia, threw out a criminal conviction of the defendant Alfred Caronia, a pharmaceutical sales person, for an...more
The Second Circuit, New York's federal court of appeals, this week issued its long-awaited decision in United States v. Caronia and vacated the conviction of a pharmaceutical sales representative for off-label promotion. In a...more
In a much-anticipated opinion, the U.S. Court of Appeals for the Second Circuit vacated and remanded the conviction of Alfred Caronia, a former pharmaceutical sales representative convicted of conspiring to introduce a...more
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Mumford & Sons at Saltair tonight sold out
Published August 22, 2012 11:32 am
This is an archived article that was published on sltrib.com in 2012, and information in the article may be outdated. It is provided only for personal research purposes and may not be reprinted.
Two other music options tonight besides 311 & Slightly Stoopid at Usana:
Mumford & Sons British folk rockers Mumford & Sons, whose breakout hit from their "Sigh No More" album is "The Cave," will bring their tour to Saltair. When • Wednesday, 8 p.m.Where • Saltair, 12408 W. Salt Air Drive, Magna Tickets • Sold out
Theophilus LondonNew wave-pop artist Theophilus London will perform with Dopethought, The Vibrant Sound and Flash & Flare. When • Wednesday, 9 p.m.Where • Urban Lounge, 241 S. 500 East, Salt Lake CityTickets • $15 in advance, $17 day of, at 24Tix
Reader comments on sltrib.com are the opinions of the writer, not The Salt Lake Tribune. We will delete comments containing obscenities, personal attacks and inappropriate or offensive remarks. Flagrant or repeat violators will be banned. If you see an objectionable comment, please alert us by clicking the arrow on the upper right side of the comment and selecting "Flag comment as inappropriate". If you've recently registered with Disqus or aren't seeing your comments immediately, you may need to verify your email address. To do so, visit disqus.com/account.comments powered by Disqus
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OpenCongress Blog
Blog Feed Comments Feed More RSS Feeds
Congress LinksSeptember 23, 2008 - by Donny Shaw
It's hard not to focus on the gigantic bailout plan being worked out, but there are some other important things also happening in Congress these days:
Credit Card Holders Bill of Rights Passes House
>By a vote of 312 to 112, the U.S. House of Representatives voted today to pass HR 5244, the Credit Cardholders Bill of Rights. The bill would curb a number of predatory credit card lending practices that can unfairly trap consumers in debt. In light of the overwhelming vote in the House, Consumers Union called on the Senate to include the reforms as part of any Wall Street bailout package. Market Watch
A Plan to Fund the Government
>According to a draft version of the CR, House Democrats would fund most federal government programs at FY08 levels until March 6 unless Congress acts before that. The draft also includes $5.1 billion for the Low Income Home Energy Assistance Program. House Democratic leaders had previously discussed including the funding in an economic stimulus package valued at about $50 billion. The package also includes $25 billion in loan guarantees for the U.S. auto industry that was authorized in legislation enacted last year. OMB Watch
Great Lakes Compact
>The House ratified a compact Tuesday to prevent the diversion of water from the Great Lakes, one of the world's largest sources of fresh water. Eight Great Lakes states negotiated the compact after more than four years of talks involving business, scientific and environmental interests. Supporters said the protections against diverting water were needed to guard the lakes from future depletion. AP
Senate Passes ALS Registry
>After a long and hard-fought battle between Majority Leader Harry Reid (D-NV) and Senator Tom Coburn (R-OK), agreement was reached today to pass the ALS Registry Act (S 1382) by unanimous consent. This bill was a part of the so-called "Coburn Omnibus" package. It would establish a registry to collect data on amyotrophic lateral sclerosis (ALS) and other motor neuron disorders, among other things. Senatus
Possible Bush-Senate Tax Agreement
>The fate of a bill to extend expiring tax breaks remains in doubt, even as the Senate and the White House headed toward an agreement Tuesday. The Senate is expected to take several votes leading to passage of a bill that would extend expiring provisions, provide a one-year "patch" to the alternative minimum tax and provide new incentives for renewable energy and conservation. The package also includes tax relief for victims of this year's natural disasters. CQ


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Blog: Why your CV is no longer enough
Click here for the hard truth about the current job marketAugust 31, 2015 8:50
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MIDEAST STOCKS-Markets to rise on stronger global environment
Abu Dhabi's ADWEA in talks with banks for $350 mln project bond
Emirates hints at no Dubai Airshow orders, pushes decision on A350/787 to next year
UAE minister says plans to boost oil output capacity on track
MIDEAST STOCKS-Saudi, Egypt markets barely move in early trade
Qatar Q2 GDP growth accelerates to 4.8 pct year/year
UAE says reforms will better protect foreign workers
United Arab Bank secures $125 mln three-year loan
MIDEAST STOCKS-Saudi hit by weak oil, commodities; Egypt down modestly
MIDEAST STOCKS-UAE markets narrowly mixed in thin, early trade
Dubai's companies have come a long way since they were surrounded by doomsday predictions and debt last year. But as they start to offload assets, are they jumping or are they being pushed?
December 12, 2010 8:51 by Eva Fernandes
DIC is the private equity arm of Dubai Holding, and it's not the only major Dubai company offloading assets. Early this week the National also reported that Istithmar World is considering selling its share in a shopping and entertainment development in Cape Town. Istithmar, which is owned by Dubai World, hasn't confirmed the speculation surrounding the sale of the Victoria and Alfred Waterfront shopping and entertainment complex, but a source within Dubai World has told the paper Istithmar is prepared to sell if it receives an attractive offer.
And though Dubai World has recently worked on a debt-restructuring, the past year has seen it offload a number of assets, including a $254 million stake in the former Metropole Hotel building in London, International Hotel Investments (IHI) and an exit from a $50 million fund to develop and own 30 no-frills Tune hotels.
The sale of the waterfront shopping and entertainment complex is still in its speculative phase, but Dubai World seems to have the right idea – sell the assets when you can, at your own discretion and in your own time. In the case of Alliance, DIC, by holding on too long, seems to have lost out against its will and in a deal that was beyond its control.
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2 Comments
Your analysis shows that you are out of your depth and lack the sophistication to infer judgement on financial transactions that are calculated and deliberate. Every private equity investor knows that sometimes its best to walk away than throw more good money after bad. This is not a story of being out of control, they knew exactly what they were doing and how to do it. Check your facts and maybe you want to look into another of their companies, which they handled skillfully in a manner of their choosing.
Very true, Dubai Inc. is in control. Besides, we did not see any attempts on the report's part to reach out to the companies for comments or perspective. Tabloid journalism at its best!
All eyes on Google
December 12 2010
The annual Boring Conference
December 12 2010


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Marketing Sunnyvale, CA, United States Company Overview Ruckus Wireless is a pioneer in the wireless infrastructure market, enabling carriers and enterprises to stay ahead of the exploding demand for high-bandwidth applications and services. The Ruckus Smart Wi-Fi technology8/3/2015 Sunnyvale, CA Save This Job
Marketing Foster City, CA, United States Director of Brand & Corporate Marketing About Conviva With a view into billions of streams per month from billions of unique devices, only Conviva can deliver online video providers the power to navigate the pitfalls of8/2/2015 Foster City, CA Save This Job
Description MarkMonitor?the world leader in brand protection and a Thomson Reuters Intellectual Property & Science business?is looking for a of Director of Digital and Content Marketing who will be responsible for leading content marketing and digital strategy at MarkMonitor.8/1/2015 San Francisco, CA Save This Job
At Pandora, we're a unique collection of engineers, musicians, designers, marketers, and world-class sellers with a common goal: to enrich lives by delivering effortless personalized music enjoyment and discovery. Peopleâthe listeners, the artists, and our employeesâare9/3/2015 Oakland, CA Save This Job
San Jose, CAFull-time Company Description We have built a unique visual employee engagement platform that is transforming the way companies do business. Hoopla TV connects, challenges, motivates and inspires salespeople and employees in every department. It integrates with9/24/2015 San Jose, CA Save This Job
Location: Redwood City, CA Type: Full-time Time frame: Immediate About QuanticMind QuanticMind, the Platform for Smarter Advertising, is a rapidly growing software-as-a-service company. It is the performance leader in predictive advertising management software for paid9/21/2015 Redwood City, CA Save This Job
The Content Marketing Manager is responsible for the hands on generation of content for our Spigit global marketing programs. Spigit is the leading B2B SaaS platform for crowdsourced innovation. Content is at the heart of all of our demand generation channels. You will create9/17/2015 San Francisco, CA Save This Job
Req No. 2015-1730 Job Locations US-CA-South San Francisco Category Marketing Type Regular Full-Time More information about this job: Collaborative, assertive, flexible, passionate, driven, inspired. These aren?t just nice words, they?re the start of every great Fluidigm9/15/2015 South San Francisco, CA Save This Job
The Customer Marketing Manager will be responsible for flawlessly executing an effective customer communication strategy. The right candidate must be creative, have a strong attention to detail, a self-driven problem-solver who takes the initiative in driving projects forward9/11/2015 San Francisco, CA Save This Job
Foster City, California Job Description All Covered, a division of Konica Minolta Busines Solutions USA, Inc., is currently seeking a Marketing Coordinator to join our team. Job Summary: The Marketing Coordinator manages our collateral, case studies, give aways, events, web9/8/2015 Foster City, CA Save This Job
Job ID #:10920Location:US-CA-San Francisco Functional Area:MarketingDepartment:TripIt-Marketing Position Type:US Full TimeEducation Required:Bachelors Degree Experience Required:1 - 3 YearsRelocation Provided: Share: Share on Facebook! Facebook Share on LinkedIn! LinkedIn Share8/31/2015 San Francisco, CA Save This Job
Finance San Francisco, CA, United States About Indiegogo Indiegogo was started with the simple mission to democratize the way ideas get funded and become a reality. Our founders-- Danae Ringelmann, Eric Schell, and Slava Rubin--struggled to find funding for projects and8/31/2015 San Francisco, CA Save This Job
Campbell, CA firstname.lastname@example.com At Bitglass, we are on a mission to enable enterprises to adopt public cloud applications while keeping their sensitive data secure. As the leading Cloud Access Security Broker (CASB), our innovative technologies deliver total data protection for8/31/2015 Campbell, CA Save This Job
Job Type: Full Time Location: Belmont, CA Department: Product Marketing RingCentral is looking for a Product Marketing Manager who will be responsible for representing RingCentral?s Office product with carrier partners. This individual will drive the definition of partner8/17/2015 Belmont, CA Save This Job
Palo Alto, California, United States Marketing DESCRIPTION Fulltime, Palo Alto Issuu is the world's leading digital publishing platform. We're looking for a new member to join our fantastic team. With amazing people, unique ideas and stunning technology, we're changing the8/17/2015 Palo Alto, CA Save This Job


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June 01, 2005
After impressing scouts at the Nike combine in Athens, GA last month, QB Nick Prochak (6-3 212) of Spartanburg gets the chance this month to show off his skills again in a more personal setting. He's about to embark on about a month of on campus camps where recruiters can grade his every move. Prochak is gonig to Maryland this weekend, USC next weekend and Clemson the weekend after that. He will go to Georgia in July. He has not been offered but he's getting solid interest from those schools along with Vanderbilt and Furman. Prochak said he has talked several time with Clemson recruiter David Blackwell and he feels Clemson is close to offering. He lists USC, Clemson and Georgia as his three favorites right now.Tweet
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NPR Newscast
4min 45sec
October 2, 2015 Job growth turned out to be a lot slower in September than most economists had been assuming. Now, with hiring looking weak, they think the Federal Reserve may put off any rate increase until 2016.
Capterpillar says it plans to lay off up to 10,000 workers, with many of those cuts coming in Illinois, amid a slide in equipment orders.
Scott Olson/Getty Images
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September 30, 2015 So far, most Americans have benefited from falling commodity prices: Consumer inflation has remained low. But now the pain is spreading as companies like Caterpillar and Alcoa respond to hard times.
September 28, 2015 At an aviation conference, analysts predicted lower prices are coming for air travel — and for drones — this holiday season. Cheap fares will be welcome news. Cheap drones may be a different story.
The tables are set in the State Dining Room of the White House for Friday's state dinner honoring visiting Chinese President Xi Jinping.
Manuel Balce Ceneta/AP
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September 24, 2015 President Obama is hosting Chinese leader Xi Jinping at a state dinner Friday. The menu features American favorites with "nuances of Chinese flavors." Ne-Yo, a part-Chinese R&B artist, will perform.
The International Monetary Fund says the U.S. and China have a combined annual gross domestic product of about $30 trillion.
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September 23, 2015 Even U.S. companies that don't have close ties with China have to be concerned with its slowing growth. When China buys fewer goods and commodities, prices fall for producers everywhere.
A police officer keeps watch outside the Federal Reserve headquarters in Washington, D.C., where policymakers weighed whether to boost interest rates.
Kevin Lamarque/Reuters/Landov
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September 17, 2015 The Federal Reserve chose to leave interest rates unchanged Thursday. For the central bank even a decision to do nothing is a big deal, creating all sorts of winners (homebuyers) and losers (savers).
Federal Reserve Chair Janet Yellen, speaking at a news conference in Washington on Thursday, said the U.S. economy has been performing well but the global outlook is more uncertain.
Jacquelyn Martin/AP
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September 17, 2015 The Federal Reserve decided to leave interest rates unchanged at historically low levels, even though the U.S. economy has been gaining strength. The Fed has kept a key rate near zero since late 2008.
Federal Reserve Chair Janet Yellen testifies before the Senate Banking Committee in July. This week, Yellen and other policymakers are weighing the Fed's first rate increase in nine years.
Susan Walsh/AP
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September 16, 2015 Some economists say the Federal Reserve should leave rates alone, but many say super-low rates have big risks, too. They argue that the central bank needs to push rates back up to historic norms.
Federal Reserve Chair Janet Yellen and other policymakers will meet in Washington, D.C., this week to weigh a possible increase in interest rates.
Manuel Balce Ceneta/AP
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September 15, 2015 This week, the Federal Reserve will be making decisions that could affect your ability to borrow. Because it works behind closed doors, it can seem mysterious. Here's what the Fed is and does.
There was good news along with the bad at the New York Stock Exchange this week.
Richard Drew/AP
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August 28, 2015 Markets have been seeing some of the biggest stock-price swings in years. And economists say the extreme volatility is starting to weigh down consumer confidence.
Specialist Michael O'Mara on the floor of the New York Stock Exchange on Tuesday. Stocks closed down 200 points after starting the day with a rally. But there's more going on in the economy than the drama on Wall Street.
Richard Drew/AP
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August 25, 2015 Stock prices may be having a meltdown, but consumers and homebuyers are still pushing the economy forward. In fact, a new round of data suggests the economy is gaining strength even as markets fall.
Trader William McInerney keeps an eye on developments at the New York Stock Exchange, Monday.
Richard Drew/AP
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August 24, 2015 Stock prices plunged Monday, prompting Wall Street analysts to talk about a "correction" in stock prices. But many savers worry that this might be the start of a long "bear" market.
August 24, 2015 The Dow Jones benchmark started Monday's session above 16,459 and fell more than 1,000 points before closing at 15,871. The index lost about 3.6 percent of its value.
Traders work on the floor of the New York Stock Exchange on Friday. The Dow Jones industrial average dropped 531 points, or more than 3 percent.
Spencer Platt/Getty Images
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August 21, 2015 Stock investors have to decide if the August downturn is just part of a normal zigzag pattern in any bull market, or the start of a bear market that could last for years.
August 20, 2015 The TV ads say rules involving retirement advice must be "fixed," but they may leave you scratching your head. Brokers and insurance agents are behind the ads, which aim to block tougher new rules.
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Running the TCS New York City Marathon? FAQs are now posted on the new Marathon Help Center.
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Outpouring of sadness and shock on Twitter
SOME of Radio 1's top DJs could be squeezed out after their boss Andy Parfitt quit yesterday.
I AIM to please.
IF Saturday night TV bosses land their prize catch, it'll be Adele of a coup.
CRUSHING news for ambitious Scott Mills – Radio 1's Chris Moyles has got a new £1million contract.
DO you ever read those terms and conditions that come up when you update an application on your computer?
COMIC Relief is poised to smash the £100million barrier for the first time in its 23-year history after hard-up Brits ignored the credit crunch.
Any woman keen on bagging DJ Chris Moyles as a boyfriend could just call up his show and ask him on a date.
Chris Evans picked up two awards for his BBC Radio 2 show today but admitted he still had one unfulfilled ambition - to write a hit Hollywood film.
1 IF Lauren Gofton had changed her name to Ann Jones instead of Lauren Laverne would we ever have heard of her?
Doctor Who stars Matt Smith and Karen Gillan are to become Radio 1 DJs.
That's a bit rich..
Cheryl Cole got up well early this morning (meaning so did we - thanks for that, Chezza) to speak words on the radio for us to listen to and analyse the crap out of.
X Factor supremo Simon Cowell has himself proved to be a hit in a talent contest - after being judged the top guilty pleasure for British women.
Chris Moyles has been backed by Radio 1 controller Andy Parfitt despite his half-hour on-air rant about pay - but the BBC boss admitted: "It wasn't the best Chris Moyles programme I've ever heard."
When Chris Moyles inquired why he hadn't been paid by the BBC for two months he was told it was the computer's fault.
Chris Moyles has played down an on-air rant against the BBC for not paying him for two months, claiming he could be "moody" first thing in the morning.
Tough-talking celebrity chef Gordon Ramsay wimped out of a camping trip with David Beckham when they were woken by the sound of gunfire.
Tough-talking celebrity chef Gordon Ramsay wimped out of a camping trip with David Beckham when they were woken by the sound of gunfire.
And that's pretty much all there is to it.
Peaches Geldof: "Had a sickeningly romantic day today...croissants, strolled through the Champs Elysees, visited an art gallery then the Eiffel tower. Sigh."
IT'S a heart-wrenching moment as Radio 1 star Chris Moyles and his girlfriend say their final farewell.
Jeremy Clarkson, Andrew Neil, John Humphrys, Michael Portillo, Chris Moyles and Melanie Phillips.
Move over Yorkshire, Britain's straightest talkers now live in Birmingham.
Radio One Breakfast Show host Chris Moyles was toast last night - after he lost out on Radio Personality of the Year to stand-in Scott Mills.
DJ Chris Moyles beat the air chaos and returned to the airwaves by hosting his show from New York.
DJ Chris Moyles is to beat the air chaos and return to the airwaves on Tuesday by hosting his show from New York.
Chris Moyles was forced to miss his Radio 1 breakfast show after finding himself unable to return from New York because of the air travel chaos.
Radio 1 DJ Scott Mills racked up more than £1,000 in unpaid fines after flouting parking laws.
Generous Brits had raised a staggering £30million for BBC Sport Relief last night.
Tess Daly was putting her best foot forward again this afternoon at the latest awards bash of the season - but this time without husband Vernon Kay.
Presenters at the Baftas who clearly aren't up to it (BBC1) - Duncan James, enough said...
Big changes at Chris Moyles' Quiz Night. They've introduced the apostrophe!
We know Peter Andre said he was looking for love, but we're sure this isn't quite what he had in mind.
Big day for Katie Price today – she's hitting the PR trail HARD. Be afraid, be very afraid…
Taking time out of his promotional tour of regional supermarkets, Pete woke up this morning, smelled the Costa coffee and went on the radio NOT to talk about ex Katie Price's new nuptials.


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March 7, 2012
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he is fugly but he would be a good fucck


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Kate Middleton
Kate Middleton pregnant, for the second time: Ever since little George's birth we've been holding our breath for the announcement that he would become a big brother. On Monday 8th September, 2014, Clarence House announced via twitter that our royal baby dreams were to come true - Kate is pregnant again! There have already been rumours that this time Kate will have a little princess, we can't wait to find out.
After suffering from severe morning sickness in the early stage of her first pregnancy, there are concerns that Kate is feeling the affects of this again. We hope it doesn't last long! To get the facts on how serious severe morning sickness can be click here.
We'll keep our beady eyes peeled for any Kate Middleton pregnancy-related news. Plus stay tuned for our second royal baby bump watch gallery - we'll have all the latest pictures! Can't get enough of Kate? Why not take a look at these:
Love talking all things royal baby? Let us know whether you think the royal tot will be a boy or girl and what you think they'll be called on our Facebook fan page or tell us in a comment below.
Kate and Wills forced to take extreme measures to keep photographers away from their Norfolk home
We can't help but feel for the couple...
Royal baby names
Want to name your child after a royal? Find all the royal baby names here, plus the history…
Princess Charlotte! Kate and William announce the name of their newborn baby girl
... and she's got THREE names!
BREAKING NEWS: Kate Middleton gives birth to a baby girl!
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13 things we know about the Royal baby so far
Kate Middleton is about to pop! Here's everything we know so far...
How to get your baby to marry the royal baby
Do you fancy yourself as the next Carole Middleton? Here are 12 inventive (and rather…
Is this the biggest hint yet that the Royal baby could be on its way?
The Telegraph's chief reporter tweeted a snippet of information...
How the month your baby's born affects their life
Did you know that the highest percentage of dentists are born in December? And an unusual…
Kate Middleton wearing a blindfold and a hoody? What on earth is going on here?
We've never seen one looking so casual before. But what was the cause? We investigate...
So NOW we know what Kate and Wills' Christmas cards will look like
If you happened to be on Kate and Wills' Christmas card list, this could be the sort of…
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Lomography Austin's Diana F+ Pinhole Workshop with Angie
Let's not forget that one of the awesome functions of the Diana F+ is it's ability to become a pinhole camera. A group of Lomographers scattered around the downtown streets, seeking the perfect Pinhole shots. Most of our group had never shot pinhole photos prior to the workshop. It was exciting to try something new and to use the Diana F+ in a different manner. I must say the workshop was a lot of fun. I'm pretty sure if Sir Elton John would have attended he would consider changing his hit "Pinball Wizard" to "Pinhole Wizard". Just saying!!
Check out Angie's photographs HERE!
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written by lomographyaustx on 2012-07-30


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October 5, 2015
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L.E. Baskow
Principal dancer Tara Palsha is hoisted by other dancers ending a number during her final night in "Vegas! The Show' on Friday, July 25, 2014.
© Las Vegas Sun, 2015, All Rights Reserved


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My husband said he passes this home a lot and the irony is never lost on him. He assumed at first that maybe they were fixing it up but he said nothing ever changes.
A Wellness & lifestyle blog
Hi, I'm Kim! I'm a married mother of 2 with a passion for fitness & healthy living. We live in NW Indiana near Chicago. I am slightly obsessive, love coffee, running, Kenpo Karate & dogs. I have a passion for real food, organics, GMO labeling, Young Living essential oils & green living.
maybe they ran out of money :(
Kimberly Grabinski says
Yeah I'm sure it's something like that but they should take the sign down ;)
Robin (Masshole Mommy) says
There is a house like that near us & it's been like that forever – only the shrubbery is all overgrown and it's just plain creepy looking.


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Digestive Diseases and Sciences
, Volume 55, Issue 8, pp 2144-2161
First online:
Autoantibodies as Prognostic Markers in Autoimmune Liver Disease
- Albert J. CzajaAffiliated withDivision of Gastroenterology and Hepatology, Mayo Clinic College of Medicine Email author
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
Certain autoantibodies in autoimmune liver disease have prognostic implications that are under-utilized and under-developed. The goals of this review are to indicate progress in characterizing the autoantibodies with prognostic connotations and to indicate the feasibility and importance of discovering other markers. Prime source and review articles in English were selected by a Medline search through 2010. Antibodies to soluble liver antigen, actin, liver cytosol type 1, asialoglycoprotein receptor, chromatin, cyclic citrullinated peptide, and uridine glucuronosyltransferases have been associated with the occurrence, severity, and progression of autoimmune hepatitis, and antibodies to Sp100, gp210, and centromere have had similar implications in primary biliary cirrhosis. Antibodies to soluble liver antigen have shown the most promise in autoimmune hepatitis as they have been associated with severe histological changes, long durations of treatment, relapse after drug withdrawal, and high frequency of liver failure. Antibodies to the nuclear rim pore protein, gp210, have shown the most promise in primary biliary cirrhosis as they have been associated with severe interface hepatitis, lobular inflammation, and progression to liver failure. The major limitations of the autoantibodies have been their lack of standardized assays, low negative predictabilities, and fluctuating levels. Performance parameters will improve as critical pathogenic pathways, comprehensive testing batteries, and standardized assays through international exchange workshops are developed. Progress has been made in identifying the serological markers of prognosis in autoimmune liver disease, and they promise to reflect critical disease mechanisms and enhance patient management.
KeywordsAutoantibodies Autoimmune hepatitis Primary biliary cirrhosis
- Title
- Autoantibodies as Prognostic Markers in Autoimmune Liver Disease
- Journal
Digestive Diseases and Sciences
Volume 55, Issue 8 , pp 2144-2161
- Cover Date
- 2010-08
- 10.1007/s10620-010-1268-4
- Print ISSN
- 0163-2116
- Online ISSN
- 1573-2568
- Publisher
- Springer US
- Additional Links
- Topics
- Keywords
- Autoantibodies
- Autoimmune hepatitis
- Primary biliary cirrhosis
- Industry Sectors
- Authors
- Albert J. Czaja (1)
- Author Affiliations
- 1. Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street S.W., Rochester, MN, 55905, USA


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HEPCO was founded in 1973, by Herbert E. Peitzer [and thus "HEPCO"] an aeronautical engineer, as an engineering resource company. Current management acquired the company in 1992, and today we are a Service Disabled Veteran Owned Small Business, headquartered in Saddle Brook, New Jersey serving clients in thirty States. The balance of our client base – more... is located in the New Hampshire to Virginia axis, although California is our fifth most important client State. HEPCO focuses its resource efforts primarily on four disciplines: engineering, information technology, telecommunications and executive search. We provide our clients with qualified candidates across the entire spectrum of each of these disciplines.
Our traditional strength has been providing clients with well qualified individuals on short notice, for periods ranging from a few months to several years. We provide our clients with three types of personnel. The first is permanent candidates, who become the client employee from day one. The second is temp-to-perm employees who start out as HEPCO employees, and after a defined period [usually six to twelve months], are available to hire as permanent employees for no additional fee. The third type are HEPCO employee consultants, who will work on a specific client project at the client site as our employees until their role on that project is completed, at which time the client tells us to terminate that person's services. Also, as a cleared facility, we regularly work on Department of Defense related contracts through our Tier One vendor clients.
Our markups for both consultants are very competitive and negotiable. With temp-to-perm agreements, before we can quote a markup, we need to know how long you will want the consultant to be a contract employee, prior to a no fee conversion right taking effect. Consultants who work six months before conversion have higher markups than consultants who work twelve months. In some cases, clients ask for a monthly fee schedule, so that at any point in a six or twelve month cycle, if the client takes the consultant permanent, the fee is very clearly spelled out. We can provide highly qualified individuals on a timely and cost effective basis across the entire spectrum of the engineering, communication and IT disciplines. – less–ZoomInfo


text: Jules Vintage Chair by Kirsty Hull £190$411.73€281.18$312.58 Low stock This item is not available for delivery to United States. International delivery available quantity by Kirsty Hull Location: Woodstock, GB read seller's profile see seller's complete range more items from this seller Natalie Vintage Chair £190$411.73€281.18$312.58 Tom Vintage Chair £135$292.54€199.78$222.10 Caroline Vintage Chair £280$606.76€414.37$460.65 Nicholas Chair £270$585.09€399.57$444.20 Rachel Chair £1245$2697.91€1842.47$2048.27 Michael Chair £730$1581.91€1080.32$1200.99 view all you may also like PRODUCT DETAILS DELIVERY RETURNS Made in Britain eco-friendly ask seller a question save for later Part of our Vintage collection. Jules is a small wooden chair, upholstered in hand embroidered toile. Her frame is fully restored and polished using traditional shellac products. A beautiful vintage piece suitable for any room in your home. Dimensions: H80cm x W29cm x D29cm The Vintage collection is made up of one-off restored and reupholstered pieces. If you are looking for a particular design or have a chair that needs restoring please contact me through 'ask seller a question'. I'd love to create a bespoke one-off piece for you. product code: 169058 This product is dispatched to you by Kirsty Hull. By purchasing this item you agree to the stated 28-35 days delivery lead time. In the event of any change you will be notified of a revised delivery date by email; if you do not respond you will be deemed to have agreed to the revised date. MAINLAND UK order now and receive this item by price Standard Delivery Friday 13 November £20.00$43.34€29.59$32.90 NON-MAINLAND UK estimated delivery price Highlands & Islands of Scotland 2-5 working daysfrom dispatch £40.00$86.68€59.19$65.80 Northern Ireland 2-5 working daysfrom dispatch £80.00$173.36€118.39$131.61 Other UK Islands 2-5 working daysfrom dispatch £80.00$173.36€118.39$131.61 INTERNATIONAL DELIVERY estimated delivery price Western Europe 2-5 working daysfrom dispatch £80.00$173.36€118.39$131.61 Rest of Europe 5-10 working daysfrom dispatch £120.00$260.04€177.58$197.42 You have 28 days, from receipt of cancellable goods, to notify the seller if you wish to cancel your order or exchange an item. Please note: goods that are personalised, bespoke or made-to-order to your specific requirements, perishable products and personal items sold with a hygiene seal (cosmetics, underwear) in instances where the seal is broken are non-refundable, unless faulty. Read more about our returns policy.Should you choose to return or exchange your order you will need to deliver the item(s) to the UK, where this seller is based. Kirsty Hull's return policy


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This video includes all my trip inside NYC for five days. Enjoy watching and thanks!
Shot / directed / cut by Bravewelle Madera
Music Title: Run Run
Music made and owned by: The Rivals
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