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680 posts tagged with bicycle.
Displaying 251 through 300 of 680. Subscribe:
what's wrong with this bicycle?
when my friend tries to pedal his bicycle, there is a total lack of tension in the pedals and they just seem to 'slip' and fail completely. we're at a loss. [more inside]
Bike of my dreams, not my wallet's nightmare?
I am absolutely in love with this bicycle. However, it's well outside my price range. What's the best quality and style I can get in a bike for around $300? [more inside]
I would like to ride my bike without dying.
Do you have any advice for someone new to urban cycling? [more inside]
Bicycle routes in Vancouver BC
Cycling visit to Vancouver BC. Where should I stay, where should I ride? [more inside]
Long time rider, first time flat fixer
Cycling filter: Is it a big deal if my presta valve doesn't go through the rim exactly perpendicularly? [more inside]
You mean I can keep both feet on the ground when I stop?!
Question about crank-forward bicycles, aka pedal-forward, aka flat-foot, aka semi-recumbent. [more inside]
But Which Bike is Right for ME?
Yet another special snowflake question about what bike to get, from a bicycle noob. I'd like to get out and bicycle in our (hilly) neighborhood. If I love my bike to be, I may commute on it to the train, about 7 miles from our home, or for errands. I haven't really biked since I was a kid and owned a racing 10 speed. I'm a small fairly thin woman (5'2".) I'm fine with staying on roads and hence am not taken with mountain bikes, which strike me as clunky. A little more inside. [more inside]
Can I convert from coaster to hand brakes?
I love everything about my bike except the brakes. Can my bike, which used to have coaster brakes, be converted to have both front and back hand brakes? [more inside]
What is the law in Japan regarding seating a child at the front and a child at the rear of the bicycle?
What is the law in Japan regarding seating a child at the front and a child at the rear of the bicycle? [more inside]
Shimano derailleur is derailing me all right...
Help a cycling newbie's bike love her as much as she loves it! I think I have a problem with my Shimano derailleur. [more inside]
to re-build a bicycle
Bike Mechanics 101: What tools and general knowledge should I acquire before I make an attempt at dismantling and re-constructing a bicycle? [more inside]
The Road to RAGBRAI
Suggestions for a RAGBRAI newbie? Mid-forties male, experienced bicycle rider, working on getting into shape for the ride. [more inside]
Help a bipedal human get on two wheels.
Bikefilter: I know zilch about bikes. What kind of bike do I want? [more inside]
How can I finish the Five Boro Bike Tour and still have fun while doing it?
I have a ~50 miles bike ride ahead of me this Sunday, which I've done before. However, I am completely out of shape and haven't been training much lately. What should I do to increase my chances of finishing while still having a pleasant ride and without completely destroying my Monday? [more inside]
Hydraulic brakes better for long descents?
I am looking for a cross-country bike for use in a mountain-y watershed area. I am not a skilled or graceful descender, and there is going to be a lot of descending. Bike shop guy, who I have known for a while and trust, says hydraulic discs are the way to go because of how they handle heat. Is this really a factor I should account for? [more inside]
Amsterdam Cycling Excursions
I'll be in Amsterdam for 7-10 days in early August, and am looking for some self guided bike rides out of the city and into the surrounding countryside. [more inside]
Cheap bike repair in Austin
Please recommend for me a down-and-dirty bike shop in Austin. [more inside]
Very affordable commuter/road bike?
Very affordable commuter/road bike? [more inside]
How to deal with a traffic ticket I got while on my bike in New York?
I was cycling in Central Park this morning and got a summons for running a red light with my bike. Now what? [more inside]
The 'Build a Better Bike' Trap.
What's a good bike? While looking for a bike, I realized there are (maybe) six manufacturers of frames and ten manufacturers of everything else (excluding hand-made specialty parts). Which ones are the best - 'best' meaning highest quality construction for the least added 'name-brand' expense? [more inside]
Too fat to ride?
Am I too heavy for my bike? Looking for info on weight limits for bike frames/rims. [more inside]
Portugal by cycle
Trying to plan a June bicycling trip in Portugal that either ends or begins in Coimbra. Does anyone have any experience cycling in Portugal? What are the good books? Any tips? My google-fu has failed me, and I can only seem to find places which want to take me on guided bike tours. [more inside]
Packhorse on Wheels
I ride my bike about 50-70 miles a day, but now I'd like to be able to carry a minimal amount of overnight camping gear and hiking boots with me. How can I do this while keeping the weight balanced and without breaking my back?
What should I look for in a mid-range commuter bike?
What should I look for in a mid-range commuter bike? And where should I buy one in Oxford, UK? [more inside]
Which bicycling app and mount for iPhone should I get?
What is the best / your favorite bicycle computer app for the iPhone? Also, what bike mount would you recommend for an iPhone?
Fix My Chain, Please!
I need to fix a stiff and twisted bicycle chain. Can you help? [more inside]
Bike Touring Gear
Tell me about your indispensable gear for bicycle touring. [more inside]
Fuelly for the prospective cyclist
Your recommended diet for a prospective daily bicycle commuter is requested. [more inside]
Please give me advice on my electric bicycle pusher concept? Drawing included.
I would like to build an electric bike pusher. Having never done this before, I'm seeking advice from those who build bikes, know motors, or maybe have built electric bike pushers before (best scenario. Link to my concept after the... [more inside]
How do cyclists get along with laws outside of the US?
I recently found myself in the midst of some bike politics in NYC, and one of the adjunct arguments of the anti-bike crew goes something like "people on bikes are assholes who never follow laws." What's the relationship between cyclists and road laws in countries that aren't the US (or bike-ly-unusual parts of the US)? [more inside]
If you like it then you better put a lock on it.
What's the best deal on a high-quality bicycle lock and/or chain in NYC these days? [more inside]
Bike storage negotiation
What's the most polite and likely-to-be-successful way to ask my new neighbors if I can continue to store my bike on the landing outside their apartment? [more inside]
I'm starting a Twitter account to help promote Chicago/Midwest cycling events, mostly to messy bike kids who like to ride, drink, and have fun. Alleycats, bar nights, bar rides, cyclocross, fundraisers, Messenger Prom, Bicycle Film Festival, Cycle Messenger World Championship, trick jams, etc. Help me think of a @name! [more inside]
I need an android navigation program that is more suited to my biking needs
I need an android navigation program that is more suited to my biking needs [more inside]
Where to Find This Bicycle Lamp?
Does anyone know where to buy this bicycle lamp? Maybe it is a custom job.
What is the cheapest way of getting my bike to Germany?
What is the cheapest way of getting my bike to Germany? [more inside]
I want to ride like an old-timer!
How can I ride a penny-farthing bicycle? [more inside]
Bike + baby
BikingWithBaby: Seeking recommendations for baby bike seats and compatible bicycles. [more inside]
BicycleFilter: where can I buy 3" spokes?
BicycleFilter: where can I buy 3" spokes? [more inside]
Need Advice on Cruiser Bikes
I'm changing my commute from a one mile drive/ride to an eight mile drive/ride. I'm in terrible shape (good cardio, really, but wwwwaaaaayyyyy too heavy), but want to be able to bike a few days a week to the new office. So please give me advice on the best cruiser or commuter bikes for 2011! [more inside]
Stud or Dud?
BicycleFilter: I have a Cannondale ST600 with fenders and (currently) 700x28c tires. I want to put on 700x38c studded tires. Will they fit? [more inside]
Been chained up for the past year
How are obviously abandoned bicycles treated in New York City? [more inside]
Which bicycle (for a novice) would you recommend?
Which bicycle (for a novice) would you recommend? Comparison between four bicycles [more inside]
Bike-fitting in Chicago?
I am looking for the best place in Chicago to be fit (measured) for a bicycle. [more inside]
What's the best way to donate the proceedings of a sale to charity?
I have 2 adult bikes I want to sell. And since it's that time of the year, I'm also looking for charities to donate to. So I'm thinking of combining the two things. Tell me if this is a good or a bad idea. [more inside]
My last bike was flattened in a building demolition 4 years ago. True story.
As a novice buying a bike for an urban commute, what should I keep in mind? [more inside]
Is Ortilieb really the best?
Before I go spending a lot of money on a pair of Ortilieb panniers are there any other panniers I should be thinking about? [more inside]
Looking for cycling north-shore aficionados
I'd like to take a group on bicycle from Cambridge MA to Salem MA. Route suggestions? [more inside]
First-time rider seeks bicycle advice. What should I get? From where [in Melbourne, Australia]? Rough cost?
First-time rider seeks bicycle advice. What should I get? From where? Rough cost? [more inside]
Bike quilt patterns?
Where can I find patterns for quilts that feature bicycles or bicycle parts? [more inside]


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Hallmark Hotel Bournemouth East Cliff - Bournemouth
- Free WiFi and free parking
A restaurant and free self parking are featured at this hotel along with dry cleaning/laundry. Relax in the seasonal outdoor pool and enjoy the sun loungers. The bar/lounge is a perfect place to have a drink.
Knowledgeable staff are available at the front desk 24 hours-a-day and can provide express check-out. Guests can make use of the free WiFi.
Main amenities
- 67 guestrooms
- Near the beach
- Restaurant and bar/lounge
- Breakfast available
- Seasonal outdoor pool
- 6 meeting rooms
- 24-hour front desk
- Daily housekeeping
- Garden
- Front desk safe
- Laundry service
- Conference space
What's around
- Bournemouth Beach (0.7 mi / 1.1 km)
- Bournemouth International Centre (0.7 mi / 1.2 km)
- Russell-Cotes Art Gallery and Museum (0.4 mi / 0.6 km)
- Bournemouth Pavillion Theater (0.6 mi / 0.9 km)
- Oceanarium (0.6 mi / 1 km)
Everything was fantastic, we we're there as a party of 3 groups and all the rooms were…
We had a very pleasant stay ...we'd just booked one night online thru a last minute rooms…
Enter dates to check prices
Hotel Info: 1-877-214-4288from $56
- Family Room
- Family Room
- Double Room
- Double Room, Sea View
- Twin Room
- Room
- Family Room
- Double Room, Sea View
- Double Room
- Double Room, Balcony, Sea View
- Double Room, Sea View (with Balcony)
- King or Twin Room
- Family Room
- Standard Room, 1 Single Bed
- Family Room
- Standard Room, 1 Double or 2 Single Beds
- Double Room
- Single Room, 1 Single Bed
Also popular with travelers from the USA
At a glance
Key facts
Hotel size
- This hotel has 67 rooms
- This hotel is arranged over 4 floors
- Check-in time starts at 3 PM
- Check-out time is 11 AM
- Express check-out
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
- Minimum check-in age is 18
Travelling with others
- Children (5 years old and younger) stay free when occupying the parent or guardian's room, using existing bedding
- Pets allowed (dogs and cats only) *
- 1 per room (up to 8 kg)
Extra people
- Roll-away beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- Free self parking
- Accessible parking
In the hotel
- Breakfast (surcharge)
- Restaurant
- Bar/lounge
- 24-hour room service
- Outdoor seasonal pool
- Pool sun loungers
- Golfing nearby
- Hiking/biking trails nearby
- Number of meeting rooms - 6
- Conference space
- Meeting rooms
- 24-hour front desk
- Dry cleaning/laundry service
- Luggage storage
- Wedding services
- Number of buildings/towers - 1
- Year Built 1930
- Elevator/lift
- Safe-deposit box at front desk
- Garden
- Disabled parking
- Accessible path of travel
- Accessibility equipment for the deaf
- Accessible bathroom
- In-room accessibility
In the room
- Iron/ironing board (on request)
- Premium bedding
- Private bathroom
- Shower/tub combination
- Free toiletries
- Hair dryer
- Digital TV channels
- Desk
- Free WiFi
- Daily housekeeping
- Access via exterior corridors
Special features
DiningThe Regency Brasserie - Onsite restaurant. Guests can enjoy drinks at the bar.
Awards and affiliations
Green / Sustainable Property
This property participates in Green Tourism Program, a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.
Hallmark Hotel Bournemouth East Cliff - Bournemouth's small print
Optional extras
Late check-out can be arranged for an extra charge of GBP 10.00
Pets are allowed for an extra charge of GBP 10.00 per pet, per night
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.

subset: commoncrawl


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Free DVD, CD Album, Blu Ray, Wii, Xbox and PS3 CoversTweet
Welcome to CoverDude.com! Cover Dude is a site dedicated to all things covers, if you hadnt already noticed that is :) !
Create a magazine coverWe have developed a really great magazine creation system giving you lots of really cool features allowing you to create personalised fun and professional magazine covers! Check out some of our features:
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- Download professional quality magazines for just $4.95
Cover replacement serviceWe also offer a totally free cover replacement service covering everything from CDs, DVDs and Blu Ray titles to Wii, Xbox and PS3 covers. If you have bought a game and lost the cover or case then it can be a pain finding a replacement, our service allows you to print off the cover and insert it into your own case. The service is totally free and all you need to do is search for what you are looking for or use the categories listed on the right hand side to navigate.
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- WRC: FIA World Rally Championship 5 (2015) NTS... Xbox 360 Covers
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- Roy Clark - The Lightning Fingers Of Roy Clark... CD Covers


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You searched for "Material Good"
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Satya Jewelry Cluster Pendant Necklace
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Did you know …
We have lots more in your local store! Every Nordstrom store has a unique inventory, and many items are sold exclusively in our stores, never offered online. Head to your nearest Nordstrom and check it out!
Complete Looks with "Material Good" See more


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December 2, 2012: New From Atlas Games -- Once Upon A Time 3rd Edition
Looking for an awesome game to play with the family? Look no further! Atlas Games brings you Once Upon A Time 3rd Edition! The award-winning storytelling card game encourages creativity and collaborative play. The 3rd edition features all new artwork, a revised cardlist for better play, a redesigned box (also with snazzy new artwork!), and simplified rules for quicker learning!
Make your Once Upon A Time 3rd Edition game even more interesting with Create-Your-Own Storytelling Cards. 38 story cards and 17 ending cards in this set all have blank faces, so you can add your own inspiration and imagination to the game. Just use permanent marker on the faces and let your fancy fly free!
Both items are now available through Warehouse 23!
| More
Permalink • Discuss This Post On The Forums • Archive • Illuminated Site of the Week • All SJ Games News
Copyright © 2015 by Steve Jackson Games. All Rights Reserved.


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The Safer® Brand Garden Fungicide utilizes the effectiveness of our popular sulfur-based fungicide. This organic fungicide is an effective, economical and convenient solution to the wide array of fungal blights that consumers face every day. OMRI Listed® and compliant for use in organic gardening. This organic fungicide is ideal for organic vegetable gardening and as an effective solution for rose care and tomato fungicide.
Garden Fungicide controls powdery mildew, black spot and rust. Effective rose care and organic vegetable gardening care begins with Safer® Brand Garden Fungicide.
You can use Safer® Brand Garden Fungicide RTU on roses, flowers, foliage plants, ornamentals, beans, peas and strawberries.
Directions for Use:
Spray at first sign of infection. Spray plants thoroughly to wet upper and lower surfaces of foliage.
Roses, Flowers, Foliage Plants and Ornamentals:
Apply at first sign of disease infestation. Spray at 7-10 day intervals following rain, or as needed to control powdery mildew, black spot and rust. Be sure to treat new growth and buds.
Beans and Peas:
Apply at first sign of disease infestation. Spray at 7 day intervals following rain or as needed to control powdery mildew. Can be used up until the day of harvest.
Strawberries: Apply at first sign of infestation. Repeat at 3 week intervals to control powdery mildew. Do not use on strawberry fruit used for canning.
Safer® Brand is the leader in alternative lawn and garden products. Safer® Brand recognizes the growing demand by consumers for these products, offering a wide variety of natural and organic solutions for lawn, garden, landscape, flowers, houseplants, insects and more!
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Contact us via email or Call Toll-Free 855-PERKYPET with questions or comments concerning Birdfeeders.com products.
Privacy Policy | Return Policy | © 2015 Woodstream Corporation


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Aug 19, 2015 - UK based Ben Software today announced the release of CaptureSync 1.1, an update to their multi-camera recording software for the Mac. Supporting up to 16 video and audio inputs, CaptureSync takes video and audio streams and records them to a single file that contains all streams synchronised together. CaptureSync is perfect for recording interviews, scientific experiments, psychological research, musical performances, presentations and sporting events, among many other uses.
Aug 18, 2015 - California based CS Odessa today announces a new easy-to-use solution that allows individuals and teams to design and model systems. The Systems Modeling Language (SysML) solution for ConceptDraw is a general-purpose modeling language library designed to describe systems engineering applications. The SysML Solution supports the specification, analysis, design, confirmation and validation of a wide range of systems and systems-of-systems.
Aug 17, 2015 - Eltima Software today introduces Commander One, the company's latest new file manager for Mac OS X. This free file manager features a dual-pane interface and a number of options to make browsing and managing your Mac's content as easy and as efficient as possible. The app works as an FTP & SFTP client, supports a number of archive formats, enables you to link your Dropbox accounts to the machine, queue file operations, terminal emulation, and much more.
Aug 14, 2015 - Synium Software today launches MacFamilyTree 7.6, an important update to the popular and multi award-winning genealogy application for OS X. MacFamilyTree helps you collect and record facts and data about your family history and turns them into informative reports and charts. Version 7.6 offers a new source management, the person analysis report, and a new fractal ancestor chart. In addition to these new features, version 7.6 also comes with lots of other improvements.
Aug 04, 2015 - CS Odessa today announces a new easy to use solution that allows individuals and teams to collaborate on core development issues involved in putting together a website. Suitable for web masters, UI designers, product managers, and programmers, the Website Wireframe Solution for ConceptDraw PRO supports the depiction of website layout and structure. The solution includes interface elements, navigation methods, to build a demonstration model of how a website is intended to be used by visitors.
Aug 04, 2015 - Nocturnal Aviation Software today announces FTranProjectBuilder 2.0, the only Mac-native integrated development environment (IDE) designed specifically to speed up and simplify modern Fortran code development. Created for scientists, engineers and students, FTranProjectBuilder is designed with the Mac in mind. Programmers can write and run simple or complex programs using any Mac Fortran compiler without resorting to cumbersome tools not dedicated to Fortran or the Mac.
Aug 03, 2015 - Ben Software Ltd, in conjunction with Pro Video Analytic Tools, today announced the release of SmartMotion, a new video analytics software product designed to work in conjunction with any video surveillance (CCTV) system. SmartMotion analyses captured footage at blazingly fast speeds, quickly finding events of interest, saving potentially thousands of dollars per year in terms of man-hours spent reviewing captured footage.
Jul 29, 2015 - DEVONtechnologies, LLC updates all editions of its Internet search and research tool DEVONagent as well as the context-aware search assistant DEVONsphere Express for compatibility to OS X El Capitan. Both applications also get workflow, performance, and reliability enhancements too. The updates are free and recommended for all users. Equipped with artificial intelligence, DEVONagent searches multiple sources for relevant results, and gives you power tools for your research.
Jul 27, 2015 - Popular OS X barcode creator, Barcode Basics 3.0 has now arrived at the Mac App Store and adds support for 9 new barcode types. Most of the new codes are used in national postal systems. Barcode Basics focusses on giving you professional level features, such as bar width reduction, vector output, truncation, and more. The app includes all the functions needed by graphic designers and art workers to produce industry standard barcodes which will work well on press.


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A Washington powerlifter who once made a name for herself on the national stage is now making headlines for another reason.
Ali McWeeny of Ellensburg was once a force to be reckoned with in the world of weighlifting, but that all changed three years ago when she lost her left leg in a boating accident.
Doctors said she would never lift weights again, but McWeeny had other ideas. She's now competing again, and her inspirational story was enough to bring her former coach out of retirement.
See the entire KOMO TV story here.
McWeeny is a Central Washington University alumna.
Washington Supreme Court Justice Mary Yu will be the featured speaker at a special reception from 5:CWU Education Administrator Ranks Teacher Shortage A Crisis
Within the Yakima School District alone, as many as 2,000 students—maybe more—are in classroomsCWU Communicates Cultural Competency Coaching To Corps
Two members of Central Washington University's Center for Diversity and Social Justice (CDSJ) are


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In an ongoing effort to protect the dwindling bee population, the U.S. Environmental Protection Agency (EPA) has developed new pesticide labels that prohibit use of some neonicotinoid pesticide products.
"Multiple factors play a role in bee colony declines, including pesticides. The Environmental Protection Agency is taking action to protect bees from pesticide exposure and these label changes will further our efforts," said Jim Jones, assistant administrator for the Office of Chemical Safety and Pollution Prevention.
The new labels will have a bee advisory box and icon with information on routes of exposure and spray drift precautions. The announcement affects products containing the neonicotinoids imidacloprid, dinotefuran, clothianidin, and thiamethoxam. The EPA will work with pesticide manufacturers to change labels so that they will meet the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) safety standard.
In May, the U.S. Department of Agriculture (USDA) and EPA released a comprehensive scientific report on honey bee health, showing scientific consensus that there are a complex set of stressors associated with honey bee declines, including loss of habitat, parasites and disease, genetics, poor nutrition, and pesticide exposure.
The agency continues to work with beekeepers, growers, pesticide applicators, pesticide and seed companies, and federal and state agencies to reduce pesticide drift dust and advance best management practices. The EPA recently released new enforcement guidance to federal, state and tribal enforcement officials to enhance investigations of beekill incidents.
More on the EPA's label changes and pollinator protection efforts: http://www.epa.gov/opp00001/ecosystem/pollinator/index.html
Visit our website today to learn about the design flexibility of a Morton building and the endless possibilities of partnering with our designBUILD team.
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Mitsubishi Electric's CITY MULTI L-Generation features unique HexiCoilÔ zinc-aluminum heat exchanger technology that delivers an up to 50% reduction in required refrigerant charge. Learn more at MitsubishiPro.com/Ready.
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DSX Access Systems – An industry leader in the design and sales of integrated access control products from single-door to enterprise-wide systems. www.dsxinc.com.
CustodianTM Paint Maintenance Manual. Custodian adds value to every project with easy-to-use documentation of all paint products and colors used to simplify future maintenance. Meet CustodianTM.
Spot Coolers commercial portable heating & cooling. Nationwide Emergency service 24/7. Your source for portable air conditioning rentals and sales.
The BUILDINGS brand serves commercial building owners and facilities management professionals for commercial real estate. BUILDINGS brand offers its audience of commercial building owners and facilities management professionals information on the development, construction, modernization, management and operations of commercial buildings as well as the products and services needed to support such commercial buildings and facilities management. With the information we offer, we help facilities management professionals make smarter decisions for commercial buildings.
BUILDINGS delivers relevant and timely information that equips commercial building owners and facilities management professionals with the knowledge and support they need to solve critical issues; energy management, lowering operating costs, new products for commercial buildings, security, and much more.
BUILDINGS provides facilities management professionals commercial buildings tips and trends trough online webinar events (BuildingsVIP), monthly newsletters, whitepapers and case studies.
In addition to content, BUILDINGS features a comprehensive list of products and services and is your link to the companies that provide these valuable facilities management and commercial buildings resources.
You also have the opportunity to maintain your commercial buildings certifications with BUILDINGS. Continuing Education Units are available with approved content from BOMI.
©Copyright 2014 Stamats Communications, Inc. All rights reserved / BUILDINGS


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Another area in which this device could be useful is in working with cell cultures. "If you have a mixture of multiple cells where some cells are small and other cells are big, we could separate these cell populations very easily," Papautsky explained. "Anytime you need to separate based on size, we can do it using inertial microfluidics."
The advantage of inertial microfluidics in cell separation is that it can be done easily and without cumbersome equipment. This research is leading to an entirely new generation of testing capabilities which particularly lend themselves to direct use in the field and in physicians' offices in just about any country and any economic setting.
In another paper, titled "Sorting of Blood in Spiral Microchannels" Papautsky and doctoral student Nivedita Nivedita demonstrate continuous sorting of blood utilizing inertial microfluidics via a simple passive microfluidic device. Papautsky's lab has been developing the concept of using inertia to manipulate cells and particles during the last few years. "It's truly different and innovative because these microfluidic devices are really low cost while offering very high throughput," said Papautsky.
The device is, essentially, a clear, plastic, flexible square that is relatively small in size, at about a half an inch across, but big in concept. "With this particular device we can take a drop of blood, put it in the input port in the center, and separate," Papautsky explained. The device contains four outlet ports which separate the blood into different streams, allowing the collection of outputs containing dilute plasma, red blood cells and white blood cells.
"There are a lot of clinical diagnostic tests that are based on blood," he said. One of the most common tests that are done in a hospital is the complete blood count (CBC). Through this test, a wide range of conditions like anemia, malaria or leukemia are diagnosed. "In all of these diagnost
|Contact: M.B. Reilly
University of Cincinnati


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Best Cleavage Ever (This Week)
Try not to stare too hard. Your eyes might get stuck that way.
Try not to stare too hard. Your eyes might get stuck that way.
We'd take on a croc just to get a bit closer to this Aussie hottie.
This is definitely a point of view that men around the world can appreciate more than milk and cookies.
Forget the car, the computer, your stupid iPhone. The most important invention in the last 100 years? Yoga pants.
Rawan Hage is one deliciously hot model who prides herself on being a girl whose body and looks are 100 percent natural.
Ah, beach bums.
So stunningly beautiful and effervescent that we don't even care that she doesn't eat meat.
Ladies in lace, sexpots in satin.
She's a babe who wears many hats. Also bikinis.
Once again, we present 10 highly talented women taking pictures of themselves in the best ways possible.
This mermaid's just missing her seashell bikini.
Once you click, make sure you're not operating heavy machinery or driving.


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An aggressive push to gain greater control over the Internet and restrict free speech is underway in Russia. Recently, a Russian-led coalition introduced a plan that would give the United Nations (U.N.) vast power to censor, regulate and essentially control the Internet. The U.S. government is strongly opposed to this proposal, as it would violate the very foundation of free speech and undermine the free flow of information and open conversation that the Internet provides.
Fierce international pressure opposing this legislation has caused a change of plan. Russia withdrew its current proposal on December 11th and agreed to have a more open discussion. This was seemingly a step in the right direction, but the Russian government has shown it is certainly not the end of the battle or even the beginning of a compromise.
Now, we have learned that the Russian government has started to shut down websites - the vast majority of which contain no illegal content. However, the Pirate Party of Russia said today that the websites have been blocked due to the "technological ineptness of the agency enforcing the ban."
As of Sunday, Russia's oversight agency, Roskomnadzor, had blocked 80 IP addresses, covering some 2,200 websites, but about 2,120 of those – or 96 percent – did not contain illegal content, the Pirate Party said in a press release.
Though there was no direct mention of Internet regulation in Russian President Vladimir Putin's address today in which he outlined his "moral vision for modern Russia", the recent push by the Russians to fully control Internet seems to be on par with Putin's "new vision." As Russian media reports, during the address, Putin "emphasized the importance of looking at the country's entire history rather than only the 20th century, saying: 'Russia did not begin in 1917, or even 1991'; of resisting the threat of nationalism; and the importance of the turn eastwards."
Ironically, Putin's moral vision for Russia's future may actually be mirroring its past.
As you can see, despite Russia's agreement to withdraw its proposal, the effort to silence free speech and control the Internet has already begun. Not only has Russia begun silencing its own citizens, but even after withdrawing its proposal for U.N. control of the Internet, an informal vote to get "the temperature of the room" was still taken, and the consensus was still that the U.N. should have control. The threat to the Internet and free speech continues.
The threat will only intensify if we allow regimes like Russia and China to lead the rest of us down a dangerous path to silence free speech - a path that we have fought against to preserve and protect freedom.
It's a moral contradiction like no other. Bowe Bergdahl stands accused of deserting his post to cavort with the enemy. Sergeant Charles Martland stands accused of forcefully removing a child rapist from a U.S. military base in order to defend a child. Bergdahl was treated as a hero by the Obama...
Less than 1%. That's how many Freedom of Information Act (FOIA) cases actually go to trial. Most get resolved without a trial, and without the plaintiff ever obtaining any information from the government regarding the details of its search for responsive documents. Just yesterday morning, however,
It reads like another page out of a Hollywood script. Former top IRS official Lois Lerner – at the center of a well-orchestrated scheme targeting conservative organizations – used an alias while at the IRS. In new documents just released, an IRS attorney has confirmed that Lois Lerner used another...
In what can only be explained as a bizarre (and disturbing) turn of events, former top IRS official Lois Lerner had not one, but at least two, secret personal email addresses. While Lerner was overseeing the IRS department that was targeting conservative groups for their political views, she was...


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It would be extremely helpful to show the POE status of POE switch ports.
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Make sure you are logged in and then check out the following document in Getting Started
How To Create Ideas and Feature Requests
and the Ideation Process & FAQ
It would be extremely helpful to show the POE status of POE switch ports.
I would like the following feature to be considered for implementation: Include a column in the "Port Details" summary that displays the current or most recent user to login on the endpoint connected to that switch port. When an endpoint is a Windows PC\laptop UDT displays the hostname, IP address, MAC address and Vlan. I would also like to see a column named "Most Recent User Name" or something similar. UDT provides this data when you click on the hostname, you can see a history of use …
I would like to be able to identify the speed/duplex on ports and whether the setting has been forced or auto negotiated. At the moment is that I am trying to determine which desktop PCs and switch ports have been forced as our global Win7 desktop build standard is auto/auto, whereas our old XP build differed in some offices. I am currently having to do this check manually across about 600 switches. I would therefore love to see the speed/duplex status as it appears in Cisco show interface st …
It would be great if solarwinds could develop a coms room port patching database where at a comms rooms or data centre we could map out where a floor or rack port maps to a comms rack and then to a switch port. It would have to support different rack cabling systems or setups. Maybe this could be integrated with the mapping products so that you insert a image of a rack or cable management system or floor space and then edit the ports one there as you are build a new coms room or office. At the m …
Show what port in which the access point is connected. This is but a simple request. You know where all the access points are, now show me the port in which it is plugged.
These switches do not show any layer two details at all We are moving to these switches quickly which renders UDT useless for us
These switches do not show any layer two details at all We are moving to these switches quickly which renders UDT useless for us
This is related to my post in the UDT forums - UDT not working on Nexus FEX units Currently Cisco Nexus FEX layer 2 access ports are not populating the vmMembershipSummaryTable because the port ifindex is above the limit of 2048. Because the vmMembershipSummaryTable is not populated, UDT does not know which vlans to grab when it polls the dot1DBasePortTable@vlanXXX and dot1dTpFdbTable@vlanXXX. As a side note, Switch Port Mapper in the Engineer's Toolset is able to grab the MACs and map the …
Manage or get information about Meraki Access Points via UDT in the Device Summary. Pull information from Meraki devices like Rouge Devices and user logins in APs and other information. I don't know if this is already implemented but when I had a ticket open for UDT, I was told to put a feature request.
Have a preloaded listing of Vendors and their related MAC addresses for the equipment they have. That way we can select a particular vendor and it would automatically get added to the whitelist or blacklist depending on which one you are editing. Then you do not have to manually add the MAC in any list or have to look up the MAC for a particular Vendors equipment.


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Outlawby Ted Dekker, Nicola Barber
View All Available Formats & Editions
The story of how I, Julian Carter, and my precious two-year old son, Stephen, left Atlanta Georgia and found ourselves on a white sailboat, tossed about like a cork on a raging sea off of Australia's northern tip in 1963, is harrowing.
But it pales in comparison to what happened deep in the jungle where I was taken as a slave by a savage tribe unknown to the… See more details below
The story of how I, Julian Carter, and my precious two-year old son, Stephen, left Atlanta Georgia and found ourselves on a white sailboat, tossed about like a cork on a raging sea off of Australia's northern tip in 1963, is harrowing.
But it pales in comparison to what happened deep in the jungle where I was taken as a slave by a savage tribe unknown to the world. Some places dwell in darkness so deep that even God seems to stay away.
There, my mind was torn in two by the gods of the earth. There, one life ended so another could begin.
Some will say I was a fool for making the choices I made. But they would have done the same. They, too, would have embraced death if they knew what I knew, and saw through my eyes.
My name is Julian and this is my story. But more, it is the story of my son who was born to change the world.
From deep in the impenetrable jungles where New York Times bestselling author Ted Dekker was born and raised, comes OUTLAW, an epic...
Editorial Reviews
Told with gritty realism to match The Hunger Games, Ted Dekker's Outlaw is an epic story of triumph over trial and the far-reaching power of great personal sacrifice.Novel Crossing
"Dekker's crossed a new threshold with OUTLAW. It's like nothing he's ever written, while at the same time, touching on the themes that made his previous works enjoyable. You can tell through the story that he's excited about the plot and the story and the message, and hopes that along the journey of reading, readers will go through just a bit of the journey he took when writing it. It's an astounding novel. But the most exciting part of this story is where it's going."
Life Is Story
"THE SANCTUARY may make you wonder if prisons manufacture more criminals than they rehabilitate. The vivid descriptions and drama are gripping,
and the alternating POVs add depth to the characters and story. Dekker reminds us that we are all prisoners, though it may be our minds, vs.
prison bars, holding us captive."
RT Book Reviews, 4 1/2 Stars TOP PICK
Dekker, the prolific best-selling author of more than 20 books including the "Book of Mortals" series and "The Circle" trilogy, draws on his exotic Indonesian childhood for his new thrilling adventure saga. Following the birth of her son Stephen, Atlanta-born Julian Carter dreams about a mysterious jungle creature with a haunting voice who calls to her to find and save it. After she's widowed, Julian packs up her belongings and her son and sets out to be a missionary in Melanesia. Traveling to Thursday Island in the Torre Strait, mother and son are separated when their boat capsizes. Found floating adrift, Julian is captured and enslaved on a remote section of western New Guinea by a pair of warring brothers who rule by ancient laws. When Stephen is found alive, Julian reaches into her soul and sacrifices her freedom to enable him to survive. VERDICT Combining a rich visual portrait of a Stone Age civilization and a surprising spiritual redemption, this excellent book will engage suspense and historical fiction readers.—Susan Carr, Edwardsville P.L., IL
Dekker's latest centers around the life of a mother who is stranded with a savage race unknown to modern man. When pampered Julian, a beautiful Atlanta belle, takes off for Australia and beyond, she doesn't expect to end up on a sailboat, tossed around by the sea and fighting for her life and that of her little boy, Stephen. After her rescue by strange natives she cannot understand, she is carried into the valley and forced into captivity. Soon, she discovers that she is going to die as a sacrifice to local traditions and suspicions unless she can gather her wits and find a way to make the warring tribes that have caught her spare her life. Despite the odds against her (white skin is looked upon as something to abhor, and most Tulim people find her ugly), Julian manages to form an alliance with the wife of a powerful prince in line for the throne. Unfortunately, this prince is also the brother of another man who wanted her, and if he can't have her, then he prefers her dead. Over time, Julian makes and forms alliances and, finally, presented with an unexpected gift she treasures above all else, finds a way to survive her captivity. Although the author exhibits a keen imagination, the story is repetitive and lacks focus. Known primarily as a Christian writer, Dekker leans heavily on Christian analogies that are, at times, heavy-handed. For fans of Dekker's Christian-inspired fiction.
Product Details
- 9781478953654
- Publisher:
- Hachette Audio
- Publication date:
- 06/10/2014
- Edition description:
- Unabridged
- Pages:
- 9
- Sales rank:
- 1,333,250
- Product dimensions:
- 9.10(w) x 12.00(h) x 1.00(d)
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text:
Total Time:
15 mins, plus freezing and chilling time
Active Time:
15 mins
14 1/2 cups or 19 servings
This punch recipe gets its luminescence from the quinine in the tonic water, which naturally glows blue when exposed to UV light. But the quinine's not just for show: It also gives the drink a slightly bitter flavor that balances the sweeter pineapple juice, pisco, and lime juice. Make sure to place the punch bowl right underneath a couple of black lights to get the maximum glow.
What to buy: Pisco is a brandy distilled from South American white Muscat grapes. It can be found at well-stocked liquor stores or online.
Special equipment: You will need 2 medium or large powder-free latex gloves and 2 rubber bands to make the glowing hands.
To get the glowing effect, you will need a few black lights.
Game plan: To quickly flatten the tonic water for the severed-hand ice cubes, place it in a container and agitate until bubbly. Repeat several times until almost no bubbles remain. Alternatively, pour it into a container, loosely cover, and let sit overnight at room temperature.
The severed hands will need to freeze overnight, so be sure to make them at least 1 day before you plan to serve the punch.
For the punch:
Where the tonic water is actually the star.
This sauce has an intense chocolate flavor that isn't too sweet.
A peach and rum punch that dates back to 1732.


text:
New answers tagged scaling
Rescaling or Rotating a Pattern Fill Within a Shape Rescaling patterns (while not rescaling the object to which the pattern fill has been applied) is one of my favorite techniques for creating unique patterns. It's amazing how much rescaling a familiar-looking pattern can pump some energy into an illustration. To rescale a pattern fill that has been ...
Top 50 recent answers are included


text:
McKown said he's not worried about competition from another apartment complex, adding that downtown has done well with housing added to date.
"I think the residential community downtown needs to continue to grow," McKown said. "I don't think the physical real estate is there for it to become overbuilt."
Bradshaw, meanwhile, said he suspects the downtown housing market will continue its switch from the wave of for-sale residences four years ago to rental projects such as the ones he and McKown are pursuing. Bradshaw was one of several developers who had more for-sale housing projects under design when the financial pain of the Great Recession hit in 2008.
"Financing is more difficult to get, it's hard to qualify, you've got to have down payments," Bradshaw said. "And if all the demographics and studies are correct, we will have more people renting than in the past."
Bradshaw added he believes the downtown for-sale market is recovering and will be assisted by the continued development of Deep Deuce.
"There are still people buying," Bradshaw said. "They want to know what's all around them — they would like to see what it will look like when it's done. We might have gotten the cart before the horse, and should have done some rental before doing for-sale."


text:
Narrow your search
Full Grown is a company creating chairs, tables, lamps and frames in a most peculiar fashion: to cut down on wood waste, it's guiding trees to grow in the exact shapes it requires, making for one-of-a-kind pieces that take years to complete.
On today's show, Khail and Ashley celebrate a prototype battery that could someday change the way devices are made, explain how you can use your Xbox One to watch live TV without a cable subscription and check out a company growing chairs, tables and lamps directly from the ground. #TDTree
You'll be able to drop a compatible smartphone on your IKEA nightstand for a quick charge.
Do you cringe every time you come home with one of those flat boxes from IKEA? A new game called Höme Improvisåtion lets you relive the frustration virtually.
Looking for someone to serve you? No matter where you live, there's probably a startup just waiting to become your virtual butler.
The storefront for handcrafted items is another effort by the e-commerce giant to become the everything store while simultaneously gunning for Etsy's business.
South Korea's largest mobile carrier SK Telecom, together with local furniture maker Hyundai Livart, has unveiled new Internet of Things-enabled household furniture.
The Audiophiliac considers this Kickstarter project for a craftily designed turntable, audio equipment, or LP vinyl-file storage rack.
Level up your cat condo game with a custom-made Super Mario-themed feline playhouse complete with functional warp pipes.
It's an audiophile conundrum: are your speakers too big for your room, or is your room too small for your speakers?


text:
Some pilots fly for the fun of it, to get out and see the world and forget about daily life. Others fly for the utility it provides, allowing them to travel efficiently in support of their business or family commitments. Is one more important than the other? Join our latest debate.
Articles By: Air Facts Staff
From the archives: Leighton Collins flies a 747 to Paris
One of the most popular stories from the Air Facts archive is Leighton Collins's spellbinding trip report from the cockpit of an early Boeing 707 on the way to Europe. In this article, we move 10 years into the future, as Collins again flies to Europe with TWA captain Bob Buck. This time they are in the larger and more advanced 747.
From the archives: Leighton Collins on angle of attack, 1965
This article, originally published in the May 1965 issue of Air Facts, is a companion to Richard Collins's recent article on "The three keys to flying safely." Here, Richard's father considers the history of angle of attack as both a concept and an instrument, which offers important lessons for pilots of any airplane. This is not a new debate.
Debate: are single engine airplanes safe at night?
The single engine vs. twin debate has raged for decades, with some pilots even suggesting that twins are more dangerous. But what about night flying? Many pilots still get nervous when contemplating a cross country flight in a single engine airplane. Is it safe?
Top 10 articles of 2014
We're proud to release our annual review of the year that was at Air Facts. Among nearly 150 articles published in 2014, these were the 10 most popular. What were the hot topics in 2014?
Hungry Pilot: the Hangar Hotel Airport Diner
Airport Diner may not be a creative name, but this diner is far from ordinary. Right next to the famous Hangar Hotel in Fredericksburg, Texas, pilots flock to this restaurant for big breakfasts and great milkshakes.
Debate: zero-zero takeoffs?
One of the double-edged swords for pilots is the issue of Part 91 weather minimums. Unlike commercial operators, private pilots can start an instrument approach even when the weather is below minimums. For takeoff, there really aren't any minimums, so a zero-zero takeoff would be perfectly legal. But is that a good idea?
Debate: do we still need DUAT(S)?
A number of rumors (some backed up by the companies involved) suggest that DUAT(S) may be on the chopping block. Whether that happens or not, it raises an interesting question: do we still need DUAT(S)? Add your voice.
60 seconds with the FAA administrator: what would you say?
Now it's your turn. We're going to pretend you have a one-on-one meeting with FAA Administrator Michael Huerta in his office. You have one minute to tell him anything you want, so think carefully.
Debate: full flap landings?
Since the 1950s, most airplanes have been designed with wing flaps, allowing for steeper approaches, better sight pictures and lower airspeeds at touch down. But how to use those flaps has been an endless source of debate. Should you land with full flaps every time, or are partial flap landings easier and safer in windy conditions?
Hungry Pilot: Half Moon Bay, California
In the latest installment of our search for the $100 hamburger, we head west to the 3-Zero Cafe. This airport restaurant features big breakfasts and a scenic location.
Go or no go: NORDO?
Your trip today is all fun, as you flew from your home base in Delaware, Ohio (DLZ) up to Put-in-Bay, Ohio (3W2), a beautiful island airport in Lake Erie. It was a fun day on the water and a great lunch, but now it's time to head home. Is it a go or no go?
Debate: has the iPad made pilots safer?
The iPad, originally dismissed as a novelty, has now become an essential part of many pilots' flight bags, whether student pilot or airline pro. But have all these features actually made flying safer?
Debate: is there a pilot brotherhood?
Many pilots value their license not just for the privileges it unlocks, but also for the membership it represents. That membership is in the unofficial "pilot brotherhood," which bonds together aviators from around the world–regardless of race, class or location.
The Hungry Pilot: Nemacolin Resort, PA
This large hotel and resort has its own private airport, just steps from the lobby. Fly in for a good burger or a elegant French dinner–there are plenty of options at Nemacolin.


text:
HP OpenView definition
HP OpenView is a suite of business computer management or "e-services" programs from Hewlett-Packard (HP), which states that the suite is "among the world's 20 largest software businesses." The OpenView programs are frequently sold to HP 9000 and e3000 business server customers. An HP customer's IT professionals can use OpenView to manage applications, device availability, network conditions and status, system performance, service and program maintenance, and storage resources.
5 Steps Data Center Admins Can Take to Support Big Data Initiatives
When it comes to Big Data, there is no cure-all or singular approach that allows for organizations to find value in the staggering volume of data being collected. As such, our team of editors present this guide as a means of helping you to determine how you plan on using and analyzing big data - and on selecting the appropriate infrastructure components to support those efforts.
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Continue Reading About HP OpenView
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text:
Oronde Benjamin Gadsden
Position: WR
Height: 6-2 Weight: 215 lbs.
Born: August 20, 1971 in Charleston, SC
High School: Burks
College: Winston-Salem St.
Draft: Undrafted
Weighted Career AV (100-95-...): 28 (3540th overall since 1950)
Sponsor this page for $10 and help Pro-Football-Reference.com provide this service. Your message will replace this ad.


text:
a view from a walk around the neighborhood in San Luis Obispo, California
Here are some of the things that I found interesting:
teen exercise and dementia
'Physical activity can be fun and engaging, and we have to convince people of that in order to prevent some of these diseases of old age.'— Researcher Laura Middleton
link between IQ and infectious disease
"INFECTIOUS disease is taking an unexpected toll by sapping people's brainpower in the world's poorest countries. So say Christopher Eppig and colleagues at the University of New Mexico, Albuquerque, who found that a country's disease burden is strongly linked to the average IQ of its population.
a nice mention by neuroscience & psychology blogger Wray Herbert via the British Psychological Society


text:
Calcium-induced Folding of Intrinsically Disordered Repeat-in-Toxin (RTX) Motifs via Changes of Protein Charges and Oligomerization States
ABSTRACT Ligand-induced disorder-to-order transition plays a key role in the biological functions of many proteins that contain intrinsically disordered regions. This trait is exhibited by so-called RTX (repeat-in-toxin) motifs found in many virulence factors secreted by numerous gram-negative pathogenic bacteria: RTX proteins are natively disordered in the absence of calcium but fold upon calcium binding. The adenylate cyclase toxin (CyaA) produced by Bordetella pertussis, the causative agent of whooping cough, contains ∼40 RTX motifs organized in five successive blocks separated by non-RTX flanking regions. This RTX domain mediates toxin binding to its eukaryotic cell receptor. We previously showed that the last block of the RTX domain, block V, which is critical for CyaA toxicity, exhibits the hallmarks of intrinsically disordered proteins in the absence of calcium. Moreover, the C-terminal flanking region of CyaA block V is required for its calcium-induced folding. Here, we describe a comprehensive analysis of the hydrodynamic and electrophoretic properties of several block V RTX polypeptides that differ in the presence and/or length of the flanking regions. Our results indicate that the length of the C-terminal flanking region not only controls the calcium-induced folding but also the calcium-induced multimerization of the RTX polypeptides. Moreover, we showed that calcium binding is accompanied by a strong reduction of the net charge of the RTX polypeptides. These data indicate that the disorder-to-order transition in RTX proteins is controlled by a calcium-induced change of the polypeptide charges and stabilized by multimerization.
Full-textDOI: · Available from: Alexandre Chenal, Jun 22, 2015
- SourceAvailable from: Alexandre Chenal
Article: Identification of a Region That Assists Membrane Insertion and Translocation of the Catalytic Domain of Bordetella pertussis CyaA Toxin[Show abstract] [Hide abstract]
ABSTRACT: The adenylate cyclase (CyaA) toxin, one of the virulence factors secreted by Bordetella pertussis, the pathogenic bacteria responsible for whooping cough, plays a critical role in the early stages of respiratory tract colonization by this bacterium. The CyaA toxin is able to invade eukaryotic cells by translocating its N-terminal catalytic domain directly across the plasma membrane of the target cells, where, activated by endogenous calmodulin, it produces supraphysiological levels of cAMP. How the catalytic domain is transferred from the hydrophilic extracellular medium into the hydrophobic environment of the membrane and then to the cell cytoplasm remains an unsolved question. In this report, we have characterized the membrane-interacting properties of the CyaA catalytic domain. We showed that a protein covering the catalytic domain (AC384, encompassing residues 1-384 of CyaA) displayed no membrane association propensity. However, a longer polypeptide (AC489), encompassing residues 1-489 of CyaA, exhibited the intrinsic property to bind to membranes and to induce lipid bilayer destabilization. We further showed that deletion of residues 375-485 within CyaA totally abrogated the toxin's ability to increase intracellular cAMP in target cells. These results indicate that, whereas the calmodulin dependent enzymatic domain is restricted to the amino-terminal residues 1-384 of CyaA, the membrane-interacting, translocation-competent domain extends up to residue 489. This thus suggests an important role of the region adjacent to the catalytic domain of CyaA in promoting its interaction with and its translocation across the plasma membrane of target cells.Journal of Biological Chemistry 01/2012; 287(12):9200-12. DOI:10.1074/jbc.M111.316166 · 4.57 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Secretion is an essential task for prokaryotic organisms to interact with their surrounding environment. In particular, the production of extracellular proteins and peptides is important for many aspects of an organism's survival and adaptation to their ecological niche. In Gram-negative bacteria, six different protein secretion systems have been identified so far, named Type I to Type VI; differing greatly in their composition and mechanism of action (Economou et al., 2006). The two membranes present in Gram-negative bacteria are negotiated either by one-step transport mechanisms (Type I and Type III), where the unfolded substrate is translocated directly into the extracellular space, without any periplasmic intermediates, or by two-step mechanisms (Type II and Type V), where the substrate is first transported into the periplasm to allow folding before a second transport step across the outer membrane occurs. Here we focus on Type I secretion systems and summarise our current knowledge of these one-step-transport machineries with emphasis on the N-terminal extensions found in many Type I-specific ABC transporters. ABC transporters containing an N-terminal C39 peptidase domain cut off a leader peptide present in the substrate prior to secretion. The function of the second type of appendix, the C39 peptidase-like domain (CLD) is not yet completely understood. Recent results have shown that it is nonetheless essential for secretion and interacts specifically with the substrate of the transporter. The third group present does not contain any appendix. In light of this difference we compare the function of the appendix and the differences that might exist among the three families of T1SS.Research in Microbiology 03/2013; 164(6). DOI:10.1016/j.resmic.2013.03.011 · 2.71 Impact Factor
Article: Molecular Crowding Stabilizes Both the Intrinsically Disordered Calcium-Free State and the Folded Calcium-Bound State of a Repeat in Toxin (RTX) Protein[Show abstract] [Hide abstract]
ABSTRACT: Macromolecular crowding affects most chemical equilibria in living cells, as the presence of high concentrations of macromolecules sterically restricts the available space. Here, we characterized the influence of crowding on a prototypical RTX protein, RCL. RTX (Repeat in ToXin) motifs are calcium-binding nonapeptide sequences that are found in many virulence factors produced by Gram-negative bacteria and secreted by dedicated type 1 secretion systems. RCL is an attractive model to investigate the effect of molecular crowding on ligand-induced protein folding, as it shifts from intrinsically disordered conformations (apo-form) to a stable structure upon calcium binding (holo-form). It thus offers the rare opportunity to characterize the crowding effects on the same polypeptide chain under two drastically distinct folding states. We showed that the crowding agent Ficoll70 did not affect the structural content of the apo-state and holo-state of RCL but increased the protein affinity for calcium. Moreover, Ficoll70 strongly stabilized both states of RCL, increasing their half-melting temperature, without affecting enthalpy changes. The power law dependence of the melting temperature increase (ΔTm) on the volume fraction (φ) followed theoretical excluded volume predictions and allowed the estimation of the Flory exponent (ν) of the thermally unfolded polypeptide chain in both states. Altogether, our data suggest that, in the apo-state as found in the crowded bacterial cytosol, RTX proteins adopt extended unfolded conformations that may facilitate protein export by the type I secretion machinery. Subsequently, crowding also enhances the calcium-dependent folding and stability of RTX proteins once secreted in the extracellular milieu.Journal of the American Chemical Society 08/2013; 135(32):11929-34. DOI:10.1021/ja404790f · 12.11 Impact Factor


text:
1865-S $10 XF45 PCGS. Normal Date....Click the image to load the highest resolution version.
Choice XF 1865-S Ten Dollar1865-S $10 XF45 PCGS. Normal Date. The 1865-S is one of several unusual issues in which an abnormal variety (in this case, the 1865-S Over Inverted Date) is actually more common than the "regular" variety. For both types, Garrett and Guth write: "The quality of survivors is lower than average for a No Motto eagle with most examples falling into the VF category. Extremely Fine and About Uncirculated examples are extraordinarily rare ... ."
This yellow-orange example, though distinctly worn, retains warm luster through the fields. Scattered small abrasions are noted on each side, and patches of coppery encrustation cling to a few of the peripheral devices, but the overall eye appeal is excellent. An unusual feature above the coronet may be a die bulge. Population: 4 in 45, 2 finer (11/10).
From The Las Vegas Collection, Part Two.(Registry values: N4719) (NGC ID# 55MU, PCGS# 8642)
View all of [The Las Vegas Collection, Part Two ]
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text: I have eaten here a few nights while in Mui Ne. Always been happy with everything. Food are variegated and great for any taste. Not full score as plates didn't come together with my partner but sometimes waiting 5 or more minutes. Chairs also maybe should be more comfortable. Definitely I would... read more


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2010 BMW Z4 Price Analysis
Instant Market Value: $25,768Based on 41 listings
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Are 2010 BMW Z4 prices going up or down? Find out on our BMW Z4 Price Trends page.
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These prices reflect the current national average retail price for 2010 BMW Z4 trims at different mileages. They are based on real time analysis of our 2010 BMW Z4 listings. We update these prices daily to reflect the current retail prices for a Used 2010 BMW Z4.
|Instant Market Value
MSRP (also known as the sticker price) stands for the Manufacturer Suggested Retail Price. This is the manufacturer's recommended price for the vehicle including optional equipment.
The Invoice Price of a vehicle is the amount that a dealer pays to the manufacturer for the vehicle. The dealer's profit is the difference between MSRP and Invoice plus any manufacturer-to-dealer incentives.


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- Clear sky
- Temperature: 59 °F
Thu, 10/08/2015 - 19:53
- Clear sky
- Temperature: 62 °F
Thu, 10/08/2015 - 19:35
Crescent City
- Clear sky
- Temperature: 59 °F
Thu, 10/08/2015 - 19:56
Crescent City
FORTUNA – California Highway Patrol (CHP) Humboldt Area personnel joined several local agencies in the Fortuna Sunrise Rotary 'Shopping With Heroes' event Thursday night.
During the event, local police officers, firefighters, and other "heroes" joined local children and were given a $50 voucher to purchase Christmas gifts for the children and their families.
The 'Shopping With Heroes' event is sponsored by the Fortuna and Fortuna Sunrise Rotary Clubs, Fortuna Ace Hardware, and the McLean Foundation.


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Panchayati Raj
Panchayati Raj
Jammu And Kashmir
Rahul Gandhi
Home Ministry
Popular Articles About Panchayati Raj
Panchayati Raj may not solve all problems
January 31, 2002
Sowmya Sivakumar / ETIG , TNN
one of the greatest shortcomings of any centre-sponsored rural development programme is its inability to 'trickle down' to the true intended beneficiaries or the poorest of the poor. the introduction of the panchayati raj system through the 73rd amendment of the indian constitution tried to address this by prescribing a three-tier system of governance for the entire country, effective since 1993. the amendment mandates that responsibility, resources and decision-making authority be placed in the...
Panchayati Raj Articles By Date
Strengthening of panchayats must to bring peace to Jammu & Kashmir: Rahul Gandhi
August 26, 2015
JAMMU: Congress vice president Rahul Gandhi today said that strengthening of panchayats in Jammu and Kashmir was necessary to bring peace to the state. "I want to tell you that if you want peace in Jammu and Kashmir, it can be brought by Panchayati Raj because it is the grass-root level democracy in a state," Rahul said while addressing members of panchayats and corporators at a conference here. "Unless and until we empower the members of the...
MP BJP promises to bring panchayati raj
November 18, 2003
Anil Sharma , TNN
BHOPAL: Having trashed the Congress manifesto, the Bharatiya Janata Party has now promised that it shall "undo" the district government pattern introduced by the Congress five years ago, and usher in a real panchayati raj. "We shall get in real democracy by empowering the panchayats," said the BJP's chief ministerial candidate Uma Bharati at a press conference held for the release of the party manifesto. "We shall come up with a vision document on November 20, to be released by Union ministers...
Panchayati Raj bodies to be involved in labour welfare
May 19, 2008
NEW DELHI: With majority of India's workforce being in the informal sector, the Government is planning a mix of strategies involving the local bodies such as Panchayati Raj institutions in taking social security schemes to the workers. With the opening up of economy and technological advancement bringing millions of people into less secured jobs like outsourcing, construction and self-employment, the social security umbrella has to be expanded to protect...
'Directionless' ML Khattar govt issuing 'Tughlaqi' orders: Bhupinder Singh Hooda
August 24, 2015
CHANDIGARH: Former Haryana Chief Minister and Congress leader Bhupinder Singh Hooda today criticised the BJP-led state government for fixing academic qualification as criteria for panchayat poll candidates, which was later stayed by the High Court. "This government is directionless. It is only issuing Tughlaqi orders...," he said in a press conference today. The ordinance fixing minimum educational qualification for elections to Panchayati Raj...
Bureaucratic reshuffle in Arunachal Pradesh
August 7, 2015
ITANAGAR: The Arunachal Pradesh government on Thursday affected a major bureaucratic reshuffle following retirement of senior IAS officers Ganesh Koyu and transfer of K R Meena to Delhi. While Principal Secretary Dharmendra Sharma has been divested of power and hydropower charges, Labour & Employment principal secretary Satya Gopal would hold finance charge now, an official communique said here today. Agriculture commissioner and divisional commissioner (East) Hage Khoda has been...
All plan, very little work in this Panchayati Raj
April 13, 2005
NEW DELHI: The Panchayati Raj ministry's grand plans to start the process of involving PRIs and municipalities in the planning exercise may have to take a reality check. The district planning committees (DPCs), which were expected to consolidate the plans prepared by these organisations during the current year, are yet to be set up in several states, let alone start functioning. This, besides the process of setting up functioning units of panchayati raj network was scheduled to have...
Panchayati Raj yet to live up to its promise
December 18, 2006
Power to the people The three-volume State of the Panchayats Report, a brainchild of the ministry of panchayati raj, is a ready reckoner of the progress made ? and the wide gulf that remains ? in translating the spirit of the 73rd Constitutional Amendment into action. More than a decade after the amendment was passed, the record across various states is patchy. The report reflects the piquant situation faced by the central ministry that, though responsible for...
Need to empower panchayats: Nihal Chand Meghwal, Union Minister of State for Panchayati Raj
February 13, 2015
ITANAGAR: Union Minister of State for Panchayati Raj Nihal Chand Meghwal has stressed the need to empower Panchayats through effective devolution of power and functions. The minister who was visiting a Bamboo Processing Unit at Poma near here yesterday, in his address to panchayat leaders of the area, said panchayati raj in Arunachal was the oldest and added that the grassroot democratic institutions need to be empowered, an...
Over Rs 5,000 crore for Panchayati Raj schemes remains unspent
April 23, 2015
NEW DELHI: Over Rs 5,000 crore for schemes, especially the Backward Region Grant Fund (BRGF), under the Ministry of Panchayati Raj remains unspent, a parliamentary panel said today. The Standing Committee on Rural Development , whose report was tabled in Parliament today, said it was constrained to note that a huge amount of funds was lying unspent in the schemes of the Ministry of Panchayati Raj during 2014-15, especially under BRGF. "In this regard, the...
Rajiv Gandhi's Panchayati Raj remains a pipedream as UPA declares it a failure
April 24, 2013
NIDHI SHARMA , ET Bureau
NEW DELHI: Almost a quarter of a century after the late Rajiv Gandhi evangelised a decentralised government and gave the institution of Panchayati Raj his personal imprimatur, a report commissioned by Congress-led UPA government has all but declared it a failure. The expert committee, constituted by the Ministry of Panchayati Raj under one of Gandhi's trusted lieutenants Mani Shankar Aiyar , has in its report pointed out glaring flaws in...
Panchayati Raj Institution in Arunachal strengthened: Nabam Tuki
July 14, 2015
ITANAGAR: Arunachal Pradesh Chief Minister Nabam Tuki today said the three-tier panchayati raj institution in the state has been strengthened and the elected members have gained good knowledge. Tuki said this while responding to a calling attention motion in the state Assembly by BJP member Tage Taki on status of funds released to Lower Subansiri district under Rajib Gandhi Panchayat Sashatikaran Abhiyan (RGPSA) for 2014-15. Stating that in...
Panchayati Raj's debt issues to end as Finance Ministry decides to double allocations
July 10, 2015
NIDHI SHARMA , ET Bureau
NEW DELHI: Reeling under debilitating budget cuts, the panchayati raj ministry has got a new lease of life. The finance ministry has decided to double its allocation and earmark an additional Rs 1,000 crore under different heads, after much lobbying by panchayati raj minister Birender Singh. The ministry had made a strong pitch that it be given budget to fund training programmes for panchayatlevel workers and build resource centres at block and...
Digital India: Government launches mobile app; Twitter handle of Panchayati Raj Ministry
July 2, 2015
NEW DELHI: Union Rural Development Minister Chaudhary Birender Singh today launched an online mobile application for better planning of Panchayat assets and the official Twitter handle of the Ministry of Panchayati Raj, coinciding with the ongoing 'Digital India Week'. While the initiatives and programmes as well as important development of the ministry will be communicated through the Twitter handle "@MoPRInida", the ...
State government initiative to make Arunachal organic state
June 20, 2015
ITANAGAR: In a bid to make Arunachal Pradesh a hundred percent organic state, the state government has decided to launch "State Soil Health Mission ". The programme envisages proper documentation of soil health and preparation of soil map besides, distribution of Soil Health Cards to farmers so that they are guided for scientific nutrient managements, government spokesman Bamang Felix said in a statement here today. The programme shall also check...
Government mulling on increasing reservation for women in panchayats
April 24, 2015
NEW DELHI: Government may accept a suggestion by states to increase reservation for women in Panchayati Raj institutions from the present five to ten years. Rural Development Minister Birender Singh said during discussions here today that several representatives from states suggested that women members in Panchayati Raj institutions, who get a single term of five years based on reservation, are unable to achieve much. There were suggestions that the...
Panchayati Raj's debt issues to end as Finance Ministry decides to double allocations
July 10, 2015
NIDHI SHARMA , ET Bureau
NEW DELHI: Reeling under debilitating budget cuts, the panchayati raj ministry has got a new lease of life. The finance ministry has decided to double its allocation and earmark an additional Rs 1,000 crore under different heads, after much lobbying by panchayati raj minister Birender Singh. The ministry had made a strong pitch that it be given budget to fund training programmes for panchayatlevel workers and build resource centres at block and district...
Congress committed to Panchayati Raj, confusion only on process: Mani Shankar Aiyar,...
May 2, 2013
NIDHI SHARMA , ET Bureau
My target for fulfilling Rajiv's vision has always been 2018. We can get there in less than 5 years if govt acts on our recommendations, says diplomat-turned-politician Mani Shankar Aiyar . You have been passionately talking about Panchayati Raj. But your party doesn't seem to share the same passion lately... Mani Shankar Aiyar: I don't agree with you here. The commitment of the party to Panchayati Raj and...
More Popular Articles about Panchayati Raj:
Over Rs 5,000 crore for Panchayati Raj schemes remains unspent
April 23, 2015
NEW DELHI: Over Rs 5,000 crore for schemes, especially the Backward Region Grant Fund (BRGF), under the Ministry of Panchayati Raj remains unspent, a parliamentary panel said today. The Standing Committee on Rural Development , whose report was tabled in Parliament today, said it was constrained to note that a huge amount of funds was lying unspent in the schemes of the Ministry of Panchayati Raj during 2014-15, especially under BRGF. "In this regard, the...
Meghalaya ADCs may get Rs 4,500 crore aid from Centre
April 9, 2015
SHILLONG: Union Minister of State for Panchayati Raj, Nihal Chand, today said that the Centre is contemplating providing financial aid of Rs 4,500 crore to the three autonomous district councils (ADCs) in Meghalaya to strengthen these tribal bodies. He announced this while talking to reporters here on the sidelines of a meeting with officials of the three autonomous district councils. "The purpose of my visit to the state is to review the panchayati raj system besides further...
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Sitter in 1 portrait
by George Heron Hay
Captain Eyre, Army officer
Sitter in 1 portrait
by George Heron Hay
albumen carte-de-visite, 1860s
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Below is a list of all parts for the Kenmore Washer / Dryer Combo 11084832201. To find the repair part you need, you can browse the list below or you can narrow your choices by searching for a part by name or description.
This screw is sold individually.
This part mounts on the inside of the cabinet of your dryer - usually on the left side.
This part recognizes whether the door is open or closed.
This clamp is used to secure the drive motor.
Sold individually.
This part seals between the blower housing and the blower housing cover.
12-14 X 5/8. Sold individually. Your appliance will most likely require 4.
Graphite in color.
This parts covers the bulb inside the drum.
All brand logos are trademarks of their respective owners.
The PartSelect logo is a Registered Trademark of Atlantic Laundry Centres, Ltd.
Copyright © 1999-2015 , Eldis Group Partnership. All rights reserved.


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1994 CHEVROLET C/K 1500 Contact for Price
- Contact for Price
- Mileage 232,052 Miles
- Mileage 232,052 Miles
- Engine 8 Cyl
- Location Seattle, WA
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Settle into one of our expansive Jackson Hole suites with the Room to Roam package! As fall comes to Jackson Hole, bison, elk, moose, big horn sheep and mule deer begin their migration to lower elevations, giving […]
August 09, 2013
8:00 pm - 11:30 pm
TBD - Teton Village
Bravo! will host a post-concert party on August 9 to celebrate their successful fundraising season. A Spanish-themed orchestra concert will begin the celebration in Walk Festival Hall, followed by nightcaps in Teton Village. For complete information, visit www.gtmf.org/bravo.


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She send me pictures to my iPhone
Then I gotta clear em cause my girl be checking my phone
Lyric Meaning
He has to delete his mistress' naked photos, because his main girl checks his phone.
- Stop this infidelity, shame on you!
- iPhones are for girls, bro. Be a thug: get a Blackberry Storm™
(Not a paid advertisement for Blackberry™)
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Design of a logo for consulting business ( [obscured] )
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Will be used on web site, business cards and promotional material eg flyers, articles
We are a professional service/advisory business.
Specialise in financial education/financial literacy and business advice for small business
Products and services: consulting, workshops, conference speeches, books etc
We make complicated financial topics easy to understand, relevant, practical
Blue as main colour, can have 1 other colour (must work on-line and in print)
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text: The service I experienced was frankly bad. Apple ear phones taken from room. Small coins left on side table, also taken. I advised management, and they rapidly sent two representatives, they asked questions, we answered. 24 hours later I asked if they had found earphones. They said: we tried to reach you.., and that they had actually looked in the... More


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Asia Foundation President David D. Arnold Attends President Xi Jinping Welcome Dinner President Xi spoke to an audience of about 750 leaders from the private and public sectors. This marked President Xi's first stop during a week-long visit to the United States.
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How Che Screwed Jazz
Some forms of political protest are beneath contempt, and one of them is sporting–sans a shred of irony–a Che Guevara T-shirt. Yet most Che-sporting hipsters don't know that Guevara opposed art forms that carried the taint of "imperialism"–including jazz and rock music. (Uninformed hipsters? Surprise!) My colleagues at Reason produced an eye-opening video about Paquito D'Rivera, the Cuban jazz clarinetist who immigrated to the U.S. because the Cuban regime was so anti-jazz (those who stayed behind had to hide their LPs or face arbitrary confiscations).


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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
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Time and Grace Dress in Champagne
The time and place have been chosen, and now its up to you to find the best dress for the occasion! Thoughts of soft neutral tones and delicate layers come to mind, and you happily decide on this graceful shift by Ryu, which features a whimsical, beige mesh overlay, ivory ...
Era of Romance Dress
Honor the beauty of bygone days at your next occasion in this vintage-inspired floral dress! The white, flared silhouette of this belted frock is adorned with a bow-topped collar and stunning bouquets of gold and charcoal flowers - a nostalgic nod to the darling decades you dream of visiting!
Bubble Duty Dress
As your friend smiles her way down the aisle, you cue guests to fill the room with bubbles wearing this swingy shift dress by Ryu. Known for its sophistication and creativity, Ryu has been designing delicate silhouettes with whimsical details since 2008. Against a tan lining, this mesh dress boasts ...
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PRIO Director Harpviken's shortlist for the Nobel Peace Prize is out, with German Chancellor Angela Merkel on top, for her response to the refugee crisis, followed by Colombian President Santos and FARC leader Jiménez for their engagement in the peace process between the two parties.
For the rest of the list, see http://www.prio.org/About/PeacePrize/PRIO-Directors-Speculations-2015/
PRIO's Gudrun Østby beat off fierce competition to become one of the first researchers to join the newly established Young Academy of Norway.
Today, Friday 25 September, Tore Wig has successfully defended his doctoral thesis in political science at the University of Oslo: Beyond the Civil Democratic Peace: Subnational Political Institutions and Internal Armed Conflict.
Gleditsch becomes the first Norwegian to receive the Anne-Lise Meier Forschungspreis from the Alexander Humboldt Foundation.
The Research School on Peace and Conflict invites applications for the PhD course Religion, Conflict and Violence. The course is organized by Ragnhild Nordås (PRIO).
This course will focus on the relationships between religion and conflict; how this link can be understood theoretically and studied empirically, and the empirical patterns we see. The course will look at both how religion affects and is used by potential state challengers (e.g. minorities, rebel groups, terrorists) on the one hand and state policies towards potential or real challenger on the other (e.g. religious freedom/repression).
The readings, lectures and discussions will focus on global trends as well as particular cases. The course features several guest lecturers.


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Link up your social media account to automatically promote the positions at GiftCertificates.com.
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Location:Corporate Office Job Code:112 # of openings:6 Description Primary Functions: As a Customer Service Agent you will provide thorough and accurate responses to customer request or inquiries received via phone and email. Our Customer Service Agent wants to give the best9/28/2015 Omaha, NE Save This Job


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From MagicPedia, the free online encyclopedia for magicians by magicians.
Revision as of 07:12, 11 April 2009 by Philippe billot (Talk | contribs)
Cosair was a montly Magic Periodical by Teral Garrett's Magic Shop in Albany Kentucky that started around 1942. He also put out one called Perpetual Lists.
The Corsair and the Perpetual Lists overlapped each other.
There were about 85 issues of the Corsair.


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"Nobody, but Nooobody can sell you for less!"
Welcome to Crown Ford, YOUR Nashville, TN Ford dealer! This is the home of Crown Charlie - a Middle Tennessee fixture for over 30 years. When he says, "Nobody, but NOOOOBODY can sell you a Ford for less!" Believe us, he means it. After all, Crown Ford has sold well over 300,000 vehicles to the good folks in Middle Tennessee - come see for yourself why Ford in Nashville means CROWN FORD!
Crown Ford sells new Ford cars, trucks and SUV's, and a variety of pre-owned vehicles. Just take a look at the links and click on the vehicle image that sparks your interest. Shop online at your own pace - If you need us, we are here for you!
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Job No. 1 for the new CEO: Revamp the stagnating microblogging service to make it more inviting for regular folks.
Commentary: Back in June, I signed up for Apple Music, eager to make it my one-and-only music service. But after just a few weeks, I jumped ship for Spotify. Here's why.
The Internet giant is reportedly working on new Fire tablets for the holidays. Also, Verizon launches a free mobile TV service and preps for 5G wireless speeds.
Which has the most apps? Which has the coolest features? Which one is the best? The most popular streamers all have their merits, so we'll help you decide which box is right for you.
The upcoming flagship smartphone lacks a technology called optical image stabilization, which counteracts blurry or shaky images. But improvements are on the way.
A slew of new video streaming devices from Apple, Amazon, Google and Roku are lined up to compete for your holiday dollar in 2015. Which one should you buy? It's a good idea to wait for it all to shake out before you decide.
The feature shows users "what's happening in an instant," regardless of the accounts they follow. Moments could be the most important product update in Twitter's history.
In the back of your mind, you know you need to back up all of your files and pictures. But where do you start? Here's how to back up your digital life.
Netflix brings the smart home to your video-streaming experience with a DIY Wi-Fi switch designed to simultaneously turn on the TV, silence your phone, order food, and even dim the lights.
Browser plug-in F.B. Purity lets you block this and other unwanted Facebook elements.


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Fire leaves two families homelessMay 13,2013ST. JOHNSBURY — The American Red Cross says it's come to the aid of two families living in a building damaged by an early-morning fire Sunday in St. Johnsbury.
The building was evacuated after the fire broke out, and several fire departments responded. The Red Cross provided emergency needs of the families that were displaced.
For one family of two adults and a child, financial support was provided to help with food and clothing. For a family of two adults in a second apartment, food, clothing and temporary lodging was arranged.MORE IN This Just In
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Re: Auckland again, Domain Lodge?
Right at the Domain is not a bad location, you just have to walk up the hill if you come from the city centre. It is about 2 km to Parnell, and about 1.5 km to Broadway in Newmarket - which is great for shopping. If you have a close look at the map you will see that you have to walk more or less around the Domain to get to Parnell. Parnell's main road with the romantic buildings are in Parnell Road, north of the intersection with Stephens Road.
However, the Link Bus which runs on a loop course through the city, Ponsonby, Newmarket and Parnell has a stop at the hospital. Also a lot of other bus lines pass there.
The connection of the Domain Lodge with the cancer society is just that they raise money for the fight against cancer with this. Starship Hospital is nearby. It has a cancer ward for children.
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See more architecture and design movies at dezeen.com/movies
This mobile structure in Hanoi, Vietnam, by Swiss architects Bureau A has a bicycle fitted underneath so it can be cycled from place to place.
Geneva studio Bureau A designed the project as a multipurpose structure, to be used for anything from a vertical street food restaurant to an exhibition space.
The mobile structure can cycled anywhere is it needed, similar to this mobile town square that features a miniature clock tower on the back of a bicycle.
The structure belongs to Tadioto, a local bar and cultural centre who use it for art and other social events.
The bicycle was originally owned by the steel worker who built the structure, who adapted to fit in the bottom section it can be moved around easily.
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The glimmer man movie online: well get the magic grassroots, most awaited ads in bunch archives trailers reviews, coming not get anxious youth of free video titles of amitabh bachchan.
Looking for movie theater in portland, oregon?
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