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Rich, an author and Saturday Night Live writer, delivers a punch-and-jab gigglefest in his follow-up to the similarly chaotic Ant Farm. A slim book of short takes, Rich doesn't stray far from his formula-many of these pieces would work as mercifully brief (and funny) SNL skits-but it's a formula that delivers a laugh on every page. Split into thematic sections-Growing Up, Going to Work, Daily Life, Relationships, Animals and God-Rich's twisted observations are often dark, especially in the Growing Up portion; "terrifying childhood experiences" include "peek-a-boo," and the people hiding in 7-year-old Rich's closet (Freddy Krueger, Chucky, a murderer, his dead uncle, and his doctor) pine, "Man, I cannot wait to kill this kid." Rich offers this brand of humor in a wide range of flavors, going, for instance, directly from Pheidippides of 490 B.C. to an "All-you-can-eat buffet fantasy" in the Daily Life portion. Still, there isn't much here that's not laugh-out-loud funny, perfect for rainy-day/toilet-top browsing or one long, painful guffawathon.
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved. --This text refers to the Hardcover edition.
"A punch-and-jab gigglefest . . . that delivers a laugh on every page."—Publishers Weekly
"Simon Rich is still the freshest, funniest new writer today."—Chicago Sun-Times
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My 8 year old wrote a book the other day. I loved it (so much drama in the angry birds universe. Who knew). Read morePublished 5 months ago by crperkins
Entertaining,witty,odd funny. A short ,funny,irreverent look at subjects everyone but the author couldn't be bothered with musing over, and yet we laugh and join in.Published 9 months ago by Kindle Customer
A fantastic book of short stories that brought me endless smiles and laughter.Published 15 months ago by Will Beeler
Bought this after reading and enjoying Rich's Ant Farm. Hilariously funny one to three page musings about imagined conversations between free range chickens, people observing a... Read morePublished 15 months ago by Gary Messerli


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Health News Index – July/August 2000
The July/August 2000 edition of the Kaiser Family Foundation/HarvardSchool of Public Health, Health News Index includes questions about major health stories covered in the news, including questions about the Supreme Court's recent decisions and House action on proposals for providing drug coverage to seniors. The Health News Index is designed…Poll Finding Read More
A Side-by-Side Comparison of Selected Medicare Prescription Drug Coverage Proposals
This document provides a side-by-side comparison of four major federal proposals under consideration to provide outpatient prescription drug coverage to Medicare beneficiaries. It begins with a summary table comparing key features of each proposal, followed by a detailed comparison of the following major proposals: Clinton/Moynihan (The Medicare Modernization Act), House-Passed…Report Read More
Analyzing Options to Cover Prescription Drugs For Medicare Beneficiaries
This report examines the implications for Medicare beneficiaries of leading approaches to provide coverage for prescription drugs, looking at coverage, benefit levels and out-of-pocket spending. ReportReport Read More
The Implications of Medicare Prescription Drug Proposals for Employers and Retirees
This report examines the potential savings for employers who currently represent the largest source of drug coverage for seniors. The study finds substantial savings for large employers under comprehensive Medicare prescription drug proposals ranging from $5-8.5 billion in 2003 to $10-$15 billion in 2009. It also finds that the majority…Report Read More
Prescription Drug Trends: A Chartbook
Prescription Drug Trends – A Chartbook, an analysis by the Kaiser Family Foundation and the Sonderegger Research Center, University of Wisconsin-Madison, provides information about trends in prescription drug coverage, spending, prices, use, and industry structure. Although overall coverage for prescription drugs has increased over the last decade, about a quarter…Report Read More
Health News Index–May/June 2000
The May/June 2000 edition of the Kaiser Family Foundation/Harvard School of Public Health, Health News Index includes questions about major health stories covered in the news, including questions about the Congressional Democrats' proposal to have the Medicare program cover prescription drug costs for the elderly. The survey is based on…Poll Finding Read More
Medicaid Eligibility for Individuals with Disabilities
This issue paper updates the July 1999 report and provides a general overview of federal Medicaid eligibility policy for the low-income disabled population. This paper focuses on four broad groups of individuals with disabilities: children under 18; adults under 65 who are not living in institutions; adults under 65 who…Issue Brief Read More
Medicaid Managed Care for Persons with Disabilities: Case Studies of Programs in Florida, Kentucky, Michigan and New Mexico
This report, Medicaid Managed Care for Persons with Disabilities Case Studies of Programs in Florida, Kentucky, Michigan and New Mexico, provides in-depth descriptions of the case studies in these states.Report Read More
Medicaid Managed Care for Persons with Disabilities: A Closer Look
This report, Medicaid Managed Care for Persons with Disabilities: A Closer Look, presents an overview of the findings and summarizes the results of the case studies of Medicaid managed care programs that enroll persons with disabilities in four states: Florida, Kentucky, Michigan, and New Mexico. This report also draws from…Report Read More
Medicaid-Related Provisions in the Ticket to Work and Work Incentives Improvement Act of 1999
In December, the President signed into law the Ticket to Work and Work Incentives Improvement Act of 1999, which includes provisions that will give states additional options for extending Medicaid coverage to working disabled individuals. This memo presents an overview of the eligibility options offered under the new legislation (Publication…Report Read More


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Gary Coleman and Todd Bridges return as brothers Arnold and Willis Jackson for another season of family fun and life lessons.
During the third season, Arnold and Willis get held hostage by bank robbers, Mr. Drummond (Conrad Bain) celebrates his 50th birthday in the hospital, Kimberly (Dana Plato) helps a pregnant girlfriend, and Arnold the great goes missing after a more-than-effective disappearing act. Diffrent Strokes never shied away from the social and cultural issues at hand, but always managed to deliver laughs and heartfelt character development from week to week. Diffrent Strokes ran eight seasons strong, from 1978 to 1986, airing both on NBC and ABC.
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Diff'rent Strokes Season 3 is great. This is a great DVD collection to have. This is great for the entire family to watch. This is very hard to find in stores today. Read morePublished 3 months ago by Bridgett A. Richard
my wife was looking season 3 & 4 for a long time, luckily got it on amazon at reasonable price. happy with the purchasePublished 4 months ago by nikhil
Absolutely love them! Can't wait to order all the rest of the seasons! :)Published 5 months ago by Donna
Great family series. We need more good clean family shows like this, not the trash that is on TV now.Published 8 months ago by MC
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- Dr. Dennis Gross Skin Care Hydra-Pure Smart Spray - 2.5 oz$17 beautybar.comRefreshing Shield. Dr. Dennis Gross Skincare Hydra Pure Smart Spray is a one of a kind detoxifying formula that combines hydrating and anti aging properties in a sanitizing shield to protect against the harmful effects of the environment while guarding against other impurities. De stress irritated skin with this soothing and refreshing formula that contains Tea Tree and Peppermint Essential Oils. Protects against harmful effects of the environment and other impurities. Soothing and refreshing. Hydrates and improves skin texture. Sets and refreshes makeup. With a few simple spritzes, Dr. Dennis Gross Hydra Pure Smart Spray instantly protects, hydrates and betters skin texture. Use it in the morning or throughout the day as a skin pick me up and makeup setter. Especially Suited For: All skin types. Essential Elements: Hydra Pure Smart Spray contains energizing Peppermint Oil which revitalizes skin. Size: 2.5 oz. For Best Effect: Hold bottle 8 10 inches from face. Close your eyes and mouth and mist 2 3 times as needed.


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This attractive cottage enjoys a quiet courtyard setting with its own garden area, and a pub serving food less than half a mile away. Converted from the former bakery, and still retaining its original bread ovens, it sits adjacent to the owners' thatched cottage in a pretty conservation village. This lovely area invites exploration, and the south Dorset coast as well as the historic towns of Dorchester, Yeovil and Lyme Regis are all within easy reach. Weymouth, famed for its sandy beaches is just 15 miles away. Fishing, golf and horse riding locally. Shop 2 miles, pubs within 1/2 mile.
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Jun 16
June 16th Liquid Duaneo Metal Productions Odium Music Promotions Metalove Custom Banners Barely Legal Crowdpleasers Toot's Tavern Presents: Dysentery Brutal Slamming Death Metal from Waltham, MA Parasitic Ejaculation Brutal Slamming Death Metal from Santa Cruz, CA Cognitive Death Metal from New Jersey Stillbirth Death Metal from Hagen, Germany Placenta Powerfist Death Metal from Hamm, Germany Splattered Slamming Brutal Death Metal from Bay Area, CA PLUS burlesque girls between a few bands!! Doors @ 7:30pm ONLY $7 21+
Nov 8
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FUCK YOUR FACE Metal Showcase: Parasitic Ejaculation, Incisus, Septicaemia, Asterion, Cerebral Cannabis, & Thunderfuck
Sep 27
Label: Ghastly Music
Manager: email@example.com
Bio: Parasitic Ejaculation were formed in summer 2011 in Santa Cruz, CA. With the original lineup, they recorded a three-song demo, and in fall, Josh Schwartz replaced Max Paradise as the bassist. They went into the studio in winter to record their debut EP titled 'Sickening Conduct' with Max Zigman o...See Full Bio


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T.g.i. Friday's Frozen Key Lime
Total Time
Prep 5 mins
Cook 0 mins
Good drink with dinner. Reminds me of a Key Lime pie.
Make and share this T.g.i. Friday's Frozen Key Lime recipe from Food.com.
Ingredients Nutrition
- 1 1⁄4 ounces light rum
- 2 ounces lime juice
- 1 tablespoon bar sugar
- 2 scoops vanilla ice cream
- 1⁄2 scoop crushed ice
- Garnish: aerosol whipping creamand lime wheel.
- Combine ingredients in blender, blend until smooth. Serve in a tall specialty glass.
- Servings: 1.
Most Helpful
Another sweet and thick "milkshake". Used Rose's lime juice so skipped the sugar in this one. Very good. TFS


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Hotel Mozaic
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TravelPod Member ReviewsHotel Mozaic The Hague
Everything was near perfect. Wonderful room. Great staff. Well located. Off street parking. Free WiFi. Nice breakfast. Highly recommended
This review is the subjective opinion of a TravelPod member and not of TravelPod.com.
TripAdvisor Reviews Hotel Mozaic The Hague
Travel Blogs from The Hague
Looking In A Mirror Is Like A Kick To The Balls
... the end of the trip when I don't have so far to carry them. After a bit of wandering I found a few t-shirts I liked in a store that didn't seem to be the kind of massive chain you see everywhere.
When I tried them on, I found I was between sizes. The larger size was loose across the shoulders and down the back. The smaller size fit in those places, but was tight around my emerging gut.
That was the wake up call I needed.
You see, I ...
Amsterdam - Day 2
... br>
So the Royal Palace...now thats what I call a palace, silly Frenchies don't know what they are doing. I know they had a revolution and all, but if the palace is no longer a palace, call it something else. The palace was actually the town hall until the early 1800's when Luis Bonaparte, (one of Napolean's relos) converted it to the Royal Palace. Many of the decorations inside are from that era. The displays were really good, and the audio ...
Vermeer and Escher
... part for lunch), but it still has some nice churches and palaces. We gradually wended our way around to the Escher Museum, which we both really enjoyed. At least the most interesting part for me was Escher's early work, which was much more representational, and yet still had some hint of his distinctive style. None of it is famous like his more geometric work, so it was a treat to see. The Museum is in a old palace which had been used by ...
... at 11pm. which would transfer the passenger to hospital,and how sorry he was for these people ,that their journey was ending sadly...We are going slowly,just 10 knts, towards the Channel,that it wont alter our arrival time in Guernsey...We will see the White Cliffs of Dover later, on our side today
A sea day then...
Looking forward to another adventure,hope you all are well and happy... Love from us, Faye and Sam.. Pictures later..we ...
Amsterdam Walking Tour and Heineken Experience
... stop tour so we couldn't study each one. One thing I did notice though was all the carpets were really hard to identify which country was which.... All but one... You guessed it the USA has it's flag decorating its square. I was shocked that in Amsterdam people didn't have last names until the 18th century. Bonaparte declared that everyone had to have a surname so that is why a lot of Dutch people have silly last names... Or that's what they say at least! Kor informed us ...


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Six months have passed since President Obama and Cuban President Raul Castro made the historic decision to reestablish diplomatic relations between the U.S. and Cuba. Although Congress has not yet voted to lift...more
As more countries join the Madrid Protocol System for the International Registration of Marks (Madrid System), trademark owners should be sure to take full advantage of this trademark registration option. There are now 89...more
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A look at the Week 13 games in the Pac-12, including Arizona State's chance to lock up the South Division.
Golden Bears rally behind the flag of the Golden State
2hDavid Lombardi
Timing a surprise, but Myles Jack's decision is the right one
17hKyle Bonagura
Debate: Is Utah the No. 1 team in the country?
19hDavid Lombardi and Kyle Bonagura
Sport Science breaks down Arizona State's pile-on touchdown run
21hESPN.com staff
Strength in numbers in USC's backfield
21hKyle Bonagura
After a career night, Travis Wilson aims for consistency
1dChantel Jennings
Pac-12 weekend wrap: Key visitors take in Cal win, UCLA loss
1dErik McKinney
Pac-12 quarterback power rankings: Kevin Hogan is on a roll
2dDavid Lombardi
Stanford continues its remarkable offensive turnaround
2dDavid Lombardi
Pac-12 weekend rewind: Arizona State back in conversation
2dKevin Gemmell
Video: Pac-12 storylines


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A patient at The Center for New Medicine, describes her experiences working with Dr. Leigh Erin Connealy in her clinic. Josephine talks about Dr. Connealy's approach using both traditional and alternative medicine.
Sign up to get FREE access to more health tips, latest research, and exclusive offers to help you reach your health and wellness goals!


text: My wife and I returned to spend the weekend and it was like we never left. Ralph and Mary welcomed us and we felt at home. Our suite was perfect, we did nothing special Friday night when we arrived, we sat outside on their deck listened to nature and enjoyed a glass of of wine. Breakfast both days were awesome,... More


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Creator: Smart Bomb Interactive
Smart Bomb Interactive is a Video Game developing company. Its founding date is 2006 and it remains active to the present day.
Video games developed by this company:
- Bee Movie Game
- National Geographic's Animal Jam
- Pac-Man World Rally (GameCube, PC, PlayStation 2, PSP, Xbox (Cancelled))
- Sky Legends (Macintosh, PC)(TBA)
- Snoopy Flying Ace
- Snoopy vs. the Red Baron (PC, PlayStation 2, PSP)


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2002 Oldsmobile Alero GL2 2dr Coupe (3.4L 6cyl 4A)
I have 175,XXX miles on my Alero and it is running great!! For those of you who are talking crap about this car is obviously not taking care of it very well. If you take care of a car and maintain it, it will last a long time. I know a man who has a 1989 gmc safari van with almost 500,000 miles on it and still drives it to work every day! Take car of your vehicles and they will run forever!
aero-dynamic, handles great...smooth!
2002 Oldsmobile Alero GX 4dr Sedan (2.2L 4cyl 4A)
I hadn't heard anything bad about an Alero when my mechanic tried to sell one to me.
It was an '02 and I didn't have a single problem with it for 3 years.
I lived on a steep, unpaved road and the car got me up even in snow.
Then the check engine light was on and it started choking on it's own oxygen intact and emissions problems and now it sits not able to pass inspection.
So, you be the judge: is a 2002 supposed to live past 11 years and 155000 miles?
It was fine and now dead.
I actually thought the seats were comfortable.
2002 Oldsmobile Alero GLS 2dr Coupe (3.4L 6cyl 4A)
This is the worst POS on the planet. This was Oldsmobile's last car before they went belly up and I now know why. I bought it used three years old and have had nothing but problem after problem from the front bumper to the rear bumper. Too many problems to name but I will say this. The guy who sold me this POS knew what a Death Trap and it was when he sold it and got his eyes blackened and a broken nose in return after it landed me in the ditch over a mechanical issue that was recalled by GM! I bought it used so there was nothing I could do about it as the "class action lawsuit" in which the lawyers got everything and the owners got nothing was resolved.
Take it to a scrap yard, count your losses and have it cubed. OR burn it for the insurance money.
Let's see where to start.
I will start when the car was bought.
AC Fan Resistor.
Intake Gasket Manifold.
Oil Pressure Sensor.
Front Right Spring broke!
Front Shocks and Front Springs!
Front Wheel bearings went bad.
Calibers seized.
New brake calibers, new brake lines, and new rotors & pads, and the brakes still seized!
AC Clutch bad, needs AC compressor.
Cheap interior. dashboard cover is peeling and rolling backwards.
New water pump.
Then intake gasket only lasted 2 years, needed an engine.
This car is an ongoing fire pitt for your money.
None I can think of.
This car is beyond redemption.
Whether it is fixed or not, still breaks down.
Terrible car.
2002 Oldsmobile Alero GL2 4dr Sedan (3.4L 6cyl 4A)
Bought my Alero a few months ago with 72k miles on it. Solid engine, no problems thus far. Have replaced passenger side window motor, vinyl on the dash was already cracked. Decent car for the money. Uncommon tire size(225/55/16) expensive to replace.
The auto adjusting stereo volume. Volume increases with speed to compensate for wind/engine noise.
More common tire size, More fuel efficient or more powerful engine. Current engines are just in a dead zone between both. Better, higher quality interior materials. More reliable electronics (sensors, audio).
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The Wizards are 27-12 and have a break today from practice before getting ready for consecutive games vs.
The Wizards have won four of their last five games, with their lone loss coming by 31 points to the Atlanta Hawks over the weekend. Coming off Tuesday's victory vs.
Paul Pierce is raffling off his game-worn sneakers from the Wizards' 102-91 win over the Knicks on Christmas Day.
A never-ending avalanche of rumors and what-ifs are going to drop in the next month leading up to the Feb.
The real season is about to begin for the Wizards, starting with Monday's game at the Houston Rockets to open a five-game Western Conference road trip that will go a long way to determining if the


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Authorities in Ravalli County Are Searching for Missing Stevensville Man
The Ravalli County Sheriff's Office is looking for a missing 56-year-old Stevensville man.
The Ravalli County Sheriff's Office is looking for a missing 56-year-old Stevensville man.
To watch some dedicated contestants, check out Saturday's All Valley Firemen's Challenge in Stevensville during the Creamery Picnic.
Families love Stevensville's Creamery Picnic August 1 and 2. The days are jam-packed with activities for all ages.
The city of Stevensville was going to have a meeting this past week, June 11, to discuss a new ordinance that would impose restrictions on properties near the Stevensville airport, but things didn't work out as planned.
Property owners in Stevensville became very concerned a few weeks ago when the town proposed a new ordinance that would have limited the height of trees in a two-mile area around the airport to just five feet without a permit.
Montana Fish, Wildlife, and Parks is seeking information about a wolf that poached last Saturday in the Bitterroot Valley.
"It's kind of unique, we were able to actually nail-down the time of death pretty closely, between 6 and 9 P...
Crews were working up until the last minute as Habitat for Humanity held the dedication of their latest project in Stevensville.
Though these swans could be from an area just a bit north of us in Montana, other birds are beginning their migrations, which often includes a short stay at the Bitterroot's little treasure - the Lee Metcalf Wildlife Refuge...
For 49 years, the Stevensville Christmas Bird Count has continued to amaze birders with the numbers and varieties of feathered friends found within a 7-mile radius of the Stevensville Ranger Station.
Every school in the Bitterroot Valley has music for the holidays this year. Here's a list of most of these concerts.
These kids (and their instructors) have worked hard to prepare for these annual events, so take some time and go watch and listen...


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When? Anyone who has insight into when trius will file.
Sentiment: Strong Buy
right after the NDA ;-)
With a fast track designation on FDA under the GAINS act and possibly a faster NDA submission under an improved PDUFA V review process, this all could happen by this fall. Drugs such as tedizolid that are eligible for Fast Track designation are likely to be considered appropriate to receive a Priority Review. Although under the GAIN Act, as Stein has pointed out the PDUFA process has been greatly supportive if not expedited.
FDA's Fast Track Status helps expedite the regulatory process by allowing rolling submissions of data of patients enrolled in phase III clinical trials testing thus shortening the overall NDA filing and FDA decision making timelines
...if not expected.


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September through November marks the annual autumn journey of the winged beauties, as they make their way to winter homes in California and Mexico.
See the several butterfly species that are predicted to go extinct in our lifetimes.
The Albany Pine Bush Preserve in New York holds within it a rare species: the endangered Karner blue butterfly.
Traits associated with butterflies, lobsters and spiders are all present in a newly found super ancient creature that gave rise to these and other modern species. Continue reading →
A museum volunteer got an amazing surprise when he came upon the rare creature, just emerged from its chrysalis.
The North American population of monarch butterflies has decreased by 90 percent over the past two decades. Federal regulators are now considering giving the butterflies legal protection. Continue reading →
A species of butterfly uses its decorative flair for protection and also varies its color and intensity by season as predator types change.
A mysterious butterfly-shaped cloud spotted over St. Louis last week was built from actual butterflies.
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The growth of contemporary Chinese art constitutes one of the most remarkable phenomenons on the global art scene in the past twenty years. Red Flag: Contemporary Chinese Art in Montreal Collections, the first exhibition by a Quebec museum devoted to this art, features works from several Montreal collections, including the Museum's own, by some of today's greatest Chinese artists, such as the Gao Brothers, Wenda Gu, Zhang Huan, Chen Jiagang, Liu Jianhua, Wang Tiande, Zhan Wang, Ai Weiwei et Danful Yang.
June 23 to September 7: daily, 10 a.m. to 5 p.m., including statutory holidays. From September 8, 2015: Tuesday to Sunday, 10 a.m. to 5 p.m. Major exhibitions are also open on Wednesdays from 5 to 9 p.m. (at half the regular price of admission).


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China is still an riddle for the main of us, different because of culture, remote because of geography ans also not quite English-speaker. Many are those who have been cheated, attracted by cheap price and an improving production's quality. How be sure to by with the true price in this growth but mysterious country ?
You want to buy a product in China but you don't know the person to contact. There are thousands suppliers... Which one choose ?SUITE
You want to order to order a product in China but you are scared to buy something remote without seen or analysed it ?SUITE
You want to go to China looking for suppliers, or just with curiosity, to discover chinese market. Where will you go ?SUITE
McDOM is ingrained in China for helping you in your relationships with factories and suppliers. We take responsability not only for products research made in China but also for quality control. We can take charge of products transportation until your depots. Our parthnership between the most important DOM-TOM fowarding company let us garantee an optimum transportation price.
Look for products in China is one of our specialities. We put you in touch with factories and suppliers. We conduct prices researches with your specifications.
Whether you already are in business relationship with Chinese suppliers or you hope develop business with China, we can check the quality control before the goods departure. We can lock your container or group together all your products if you have several suppliers.
Nous vous accompagnons dans l'organisation de votre déplacement en Chine. Nous planifions vos visites d'usines, les rencontres avec les fournisseurs ou les autorités. Nous réservons les billets d'avion, les hôtels et un traducteur. Nous pouvons assurer votre relais sur l'Asie. We can asist you for your movings in China. We plan fatories visits and meeting with suppliers or authorities. We book your plane tickets, your hotel room and a translator. We are your chinese relay.


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Tank Tops - Women'sSave on Women's Tank Tops at Proboardshop.com! Great selection of street gear at unbelievably low prices. Proboardshop has been selling Tank Tops and outdoor gear for over 30 years and we're proud of it.
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Size: Small, Medium, LargeReg: $35.00 On Sale: $22.95
Volcom Treats Cami Tank Top - Women's
Size: Small, LargeReg: $32.95 On Sale: $18.95


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Traffic jam on 42 south New Jersey.
- Filed Under
A woman who says busy roads worsen her anxiety has sued a former employer who refused to change her schedule to avoid rush-hour traffic.
Andrea DeGerolamo also contends Fulton Financial Corp. fired her in May 2013 in retaliation for her efforts to address alleged workplace bias.
Her lawsuit, which seeks unspecified financial damages, asserts Fulton Financial's actions violated the state's Law Against Discrimination. ...


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horse.com > Western Saddles & Tack > Western Bits & Bit Guards > Item # WBE16
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Heart to Horse Box
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High quality bit features a 5" wide twisted copper wire mouthpiece for a moist, soft mouth for a better feel and 3" stainless steel flat rings. Has enough bite to regain an unresponsive horse's attention. Wire is 5/16".
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Elite Bath
3 Pc Bamboo Mural
Sale ends October 04, 2015, 6:00 PM
Item Description
|Elite BathShop All Elite Bath
|Model Number
|Alternative SKU
|Elite Bath BAMBOOAC, Elite Bath BAMBOOFP, Elite Bath BAMBOOSB, Elite Bath BAMBOOSN, Elite Bath BAMBOOTDB
Cast bronze may have irregularities such as pitting and or hairline cracks, these are not flaws but are characteristic of solid cast bronze. All Elite finishes will vary slightly in color and / or pattern. No two will be identical.
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Where is this product made??
I use this roasting pan frequently since it's just the 2 of us. Great for roasting vegetables, turkey breasts, and other smaller sized roasts. Easy to lift, fits easily in the oven, easy to clean. Stores inside my larger roasting pan saving space in the cabinet....
Roasting Pan 12.5-inch
ITEM#: 13314693This 12.5-inch roaster is constructed in durable stainless steel and highlights a removable rack and two steel handles. Enjoy beautiful oven cooked meals with this quality roaster.
- 12.5-inch roaster
- Safe up to 500 degrees Fahrenheit
- Ultra hygienic, easy to clean
- Features two steel handles for easy carrying
- Includes a removable rack, making it both a roaster and a deep dish lasagna pan
- Care instructions: Hand wash
- Materials: Stainless steel
- Dimensions: 12.5 inches long x 9.5 inches wide x 2.5 inches high
- Model: 531B
|Stainless Steel
|Roasting Pan
|see product description
|1 year Limited Manufacturer
|Stainless Steel
|Model Number
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Perfect for 2
I use this roasting pan frequently since it's just the 2 of us. Great for roasting vegetables, turkey breasts, and other smaller sized roasts. Easy to lift, fits easily in the oven, easy to clean. Stores inside my larger roasting pan saving space in the cabinet.Read More
I needed a SMALL roasting pan for my motor home. I read the reviews - that is always a determining factor whether or not to purchase. I ordered it and am so pleased. It is so SHINY and heavy in construction. I have used it once - the other reviewers were right. You can't go wrong with this roasting pan.Read More
Roasting pan
The roasting pan was not as big as I thought. My turkey did not fit on it. Wish it would have been bigger.Read More
Cook Pro Inc. 12.5-inch Roasting Pan
This is perfect size for a roast. Great quality and you couldn't beat the price. If you need a smaller roaster, I highly recommend this one.Read More
Can't Stack
The pan was OK, but I was very disappointed that they don't stack. i bought three, and they're very difficult to store.Read More
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Urban Farmhouse Kitchen
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fourthtot 22-25, F 4 Answers 1 Dec 20, 2012 in Loss of a Pet
Your ears were not open and you need to get some like mine.
Best Answer
needed to see you in a wet t-shirt
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I thought it would be funny.
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Laminaria is a plant-derived dialator they put inside of me to gently dialate the cervix as it expands and absorbs moisture, the doctor told me that my water should break on the...angierocks4901 18-21 15 Answers 15 Jul 31, 2011


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– John Cena granted another Make-A-Wish wish before Monday's RAW in Richmond when he met 9 year old Reese. WWE's Community website has photos at this link.
– WWE taped the following matches for tonight's NXT episode:
* Aiden English and Simon Gotch vs. Enzo Amore and Big Cass
* CJ Parker vs. Xavier Woods
* Sasha Banks vs. Alexa Bliss
* Adam Rose vs. Jason Jordan
* Sami Zayn vs. Tyson Kidd
– Former WWE stars JTG and Shad Gaspard were on the red carpet of an ESPYs after-party last night. They've made appearances at a charity golf tournament, an AfterBuzz pool party and other celebrity events lately as part of their Crime Time World Tour.
Must See New NXT Divas Photos & GIFs, Big Rumor on a WWE Departure, More


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|Huntington, Texas
|Former Occupation
|Graphics designer
|6' 0''
|190 lbs.
|Top 10 Finishes (Wins)*
|7 (0) As of 5/25/2012
|Career Earnings*
|$286,000 As of 5/25/2012
|Current World Rank
|Current FLW Standing
|37 (885 points)
|Best Finish in 2015
|33 - Lewis Smith Lake, 3/26/2015
|Best Finish in 2014
|47 - Lake Hartwell, 3/6/2014
|Last 3 Finishes
40 - Lake Ouachita, 8/20/2015
45 - Potomac River, 6/25/2015
71 - Lake Chickamauga, 6/11/2015
|Bassmaster Classics Fished (Won)
|2 (0) As of 5/25/2012
|FLW Championships Fished (Won)
|0 (0) As of 5/25/2012
|Angling Hero
|"David Wharton, because he was the first pro angler who was real to me."
|Home Lake
|Red River, La.
|Favorite Lake
|Least Favorite Lake
|Favorite Technique
|Shallow cranking
|Primary Fishing Strength
|Secondary Fishing Strength
|Covering water
|Biggest Weakness
|Fishing Sponsors
|Dobyns Rods, Kicker Fish, Seaguar, Browning Eyewear, Baitwerks, Elite Tungsten, Power-Pole
|Non-Fishing Sponsors
|Diamond Completion, OMNI Industrial Solutions
|Tow Vehicle (Sponsor)
|Toyota Tundra
|Favorite Food
|Spicy boiled crawfish and shrimp
|Favorite Music
|Eclectic variety
|Favorite Book/Movie
|Old Man and the Sea/A River Runs Through It
|Non-Angling Hero
|"My dad – I'm impressed with the way he's always handled things and I hope one day to be like him."
|When Not Fishing
|"Spending time with my son, bream fishing, sitting on my computer doing graphics and social networking."
|Why He Fishes
|"How many people actually get to be what they wanted to be when they were growing up."
|Click a column heading to re-sort.
|Tournament Finishes
|(Only recent tournaments are included. Not necessarily a career listing.)
*BASS events (all events because BASS does not report Tour and Open earnings separately) and FLW Tour.
Biographical data last updated: 2/8/2013
You may report any errors or omissions by clicking here. Please be certain of your information before submitting anything. Submissions will be examined, and if approved will be included in a future update.
By John Johnson BassFan Senior Editor James Watson threw a big bash at his home in Nixa, Mo. on Saturday night to celebrate the Bassmaster Open victory
By Todd Ceisner BassFan Editor About 10 minutes before he pulled his trolling motor out of the water for final time last Saturday, James Watson stopped
By BassFan Staff In part 3 of the 2015 BassFan Pro Angler Survey, you'll find the results to the second batch of questions posed to anglers who fished


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Are you Hathairad Hananantachai?Claim your profile
Publications (33)101.42 Total impact
Article: Genetic evidence for contribution of human dispersal to the genetic diversity of EBA-175 in Plasmodium falciparum[Show abstract] [Hide abstract]
ABSTRACT: Background: The 175-kDa erythrocyte binding antigen (EBA-175) of Plasmodium falciparum plays a crucial role in merozoite invasion into human erythrocytes. EBA-175 is believed to have been under diversifying selection; however, there have been no studies investigating the effect of dispersal of humans out of Africa on the genetic variation of EBA-175 in P. falciparum. Methods: The PCR-direct sequencing was performed for a part of the eba-175 gene (regions II and III) using DNA samples obtained from Thai patients infected with P. falciparum. The divergence times for the P. falciparum eba-175 alleles were estimated assuming that P. falciparum/Plasmodium reichenowi divergence occurred 6 million years ago (MYA). To examine the possibility of diversifying selection, nonsynonymous and synonymous substitution rates for Plasmodium species were also estimated. Results: A total of 32 eba-175 alleles were identified from 131 Thai P. falciparum isolates. Their estimated divergence time was 0.13-0.14 MYA, before the exodus of humans from Africa. A phylogenetic tree for a large sequence dataset of P. falciparum eba-175 alleles from across the world showed the presence of a basal Asian-specific cluster for all P. falciparum sequences. A markedly more nonsynonymous substitutions than synonymous substitutions in region II in P. falciparum was also detected, but not within Plasmodium species parasitizing African apes, suggesting that diversifying selection has acted specifically on P. falciparum eba-175. Conclusions: Plasmodium falciparum eba-175 genetic diversity appeared to increase following the exodus of Asian ancestors from Africa. Diversifying selection may have played an important role in the diversification of eba-175 allelic lineages. The present results suggest that the dispersals of humans out of Africa influenced significantly the molecular evolution of P. falciparum EBA-175.Malaria Journal 08/2015; 14(1):293. DOI:10.1186/s12936-015-0820-2 · 3.11 Impact Factor
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ABSTRACT: The Ok(a) blood group antigen basigin (BSG or CD147) is an erythrocyte receptor for the PfRh5 protein from Plasmodium falciparum. A recent study has shown that the PfRh5-BSG interaction is essential for erythrocyte invasion by P. falciparum. In this study, 6 SNPs in the BSG gene were investigated in 312 adult patients with P. falciparum malaria (109 cerebral malaria and 203 mild malaria patients) living in northwest Thailand. To examine the association between BSG SNPs and cerebral malaria, the allele and haplotype frequencies were compared in cerebral and mild malaria patients. Nonsynonymous SNPs were not assessed in the association analysis. The results showed that common BSG polymorphisms and haplotypes were not significantly associated with cerebral malaria. In conclusion, common SNPs in BSG do not influence the risk of cerebral malaria in the Thai population.Japanese journal of infectious diseases 11/2014; 67(6):432-5. DOI:10.7883/yoken.67.432 · 1.16 Impact Factor
Article: Association of the endothelial protein C receptor (PROCR) rs867186-G allele with protection from severe malaria[Show abstract] [Hide abstract]
ABSTRACT: Cytoadhesion of Plasmodium falciparum-infected erythrocytes to endothelial cells in microvessels is a remarkable characteristic of severe malaria. The endothelial protein C receptor (EPCR), encoded by the endothelial protein C receptor gene (PROCR), has recently been identified as an endothelial receptor for specific P. falciparum erythrocyte membrane protein 1 (PfEMP1) subtypes containing domain cassettes (DCs) 8 and 13. The PROCR rs867186-G allele (serine-to-glycine substitution at position 219 of EPCR; 219Gly) has been shown to be associated with higher levels of plasma soluble EPCR (sEPCR). In this study, the association of PROCR rs867186 with severe malaria is examined in Thai population. A total of 707 Thai patients with P. falciparum malaria (341 with severe malaria and 336 with mild malaria) were genotyped for rs867186. To assess the association of PROCR rs867186 with severe malaria, three models (dominant, recessive and allelic) were evaluated. The rates of non-synonymous and synonymous substitutions were estimated for the coding sequence of the PROCR gene. The rs867186-GG genotype was significantly associated with protection from severe malaria (P-value = 0.026; odds ratio = 0.33; 95% confidence interval = 0.12-0.90). Evolutionary analysis provided no evidence of strong positive selection acting on the PROCR gene. The rs867186-GG genotype showed significant association with protection from severe malaria. The present results suggest that PfEMP1-EPCR interaction, which can mediate cytoadhesion and/or reduce cytoprotective and anti-inflammatory effects, is crucial to the pathogenesis of severe malaria.Malaria Journal 03/2014; 13(1):105. DOI:10.1186/1475-2875-13-105 · 3.11 Impact Factor
Article: Diversifying Selection on the Thrombospondin-Related Adhesive Protein (TRAP) Gene of Plasmodium falciparum in Thailand[Show abstract] [Hide abstract]
ABSTRACT: Sporozoites of Plasmodium falciparum are transmitted to human hosts by Anopheles mosquitoes. Thrombospondin-related adhesive protein (TRAP) is expressed in sporozoites and plays a crucial role in sporozoite gliding and invasion of human hepatocytes. A previous study showed that the TRAP gene has been subjected to balancing selection in the Gambian P. falciparum population. To further study the molecular evolution of the TRAP gene in Plasmodium falciparum, we investigated TRAP polymorphisms in P. falciparum isolates from Suan Phueng District in Ratchaburi Province, Thailand. The analysis of the entire TRAP coding sequences in 32 isolates identified a total of 39 single nucleotide polymorphisms (SNPs), which comprised 37 nonsynonymous and two synonymous SNPs. McDonald-Kreitman test showed that the ratio of the number of nonsynonymous to synonymous polymorphic sites within P. falciparum was significantly higher than that of the number of nonsynonymous to synonymous fixed sites between P. falciparum and P. reichenowi. Furthermore, the rate of nonsynonymous substitution was significantly higher than that of synonymous substitution within Thai P. falciparum. These results indicate that the TRAP gene has been subject to diversifying selection in the Thai P. falciparum population as well as the Gambian P. falciparum population. Comparison of our P. falciparum isolates with those from another region of Thailand (Tak province, Thailand) revealed that TRAP was highly differentiated between geographically close regions. This rapid diversification seems to reflect strong recent positive selection on TRAP. Our results suggest that the TRAP molecule is a major target of the human immune response to pre-erythrocytic stages of P. falciparum.PLoS ONE 02/2014; 9(2):e90522. DOI:10.1371/journal.pone.0090522 · 3.23 Impact Factor
Article: Significant association of KIR2DL3-HLA-C1 combination with cerebral malaria and implications for co-evolution of KIR and HLA[Show abstract] [Hide abstract]
ABSTRACT: Cerebral malaria is a major, life-threatening complication of Plasmodium falciparum malaria, and has very high mortality rate. In murine malaria models, natural killer (NK) cell responses have been shown to play a crucial role in the pathogenesis of cerebral malaria. To investigate the role of NK cells in the developmental process of human cerebral malaria, we conducted a case-control study examining genotypes for killer immunoglobulin-like receptors (KIR) and their human leukocyte antigen (HLA) class I ligands in 477 malaria patients. We found that the combination of KIR2DL3 and its cognate HLA-C1 ligand was significantly associated with the development of cerebral malaria when compared with non-cerebral malaria (odds ratio 3.14, 95% confidence interval 1.52-6.48, P = 0.00079, corrected P = 0.02). In contrast, no other KIR-HLA pairs showed a significant association with cerebral malaria, suggesting that the NK cell repertoire shaped by the KIR2DL3-HLA-C1 interaction shows certain functional responses that facilitate development of cerebral malaria. Furthermore, the frequency of the KIR2DL3-HLA-C1 combination was found to be significantly lower in malaria high-endemic populations. These results suggest that natural selection has reduced the frequency of the KIR2DL3-HLA-C1 combination in malaria high-endemic populations because of the propensity of interaction between KIR2DL3 and C1 to favor development of cerebral malaria. Our findings provide one possible explanation for KIR-HLA co-evolution driven by a microbial pathogen, and its effect on the global distribution of malaria, KIR and HLA.PLoS Pathogens 03/2012; 8(3):e1002565. DOI:10.1371/journal.ppat.1002565 · 7.56 Impact Factor
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ABSTRACT: Cerebral malaria is one of the most severe manifestations of Plasmodium falciparum malaria. The sequestration of parasitized red blood cells (PRBCs) to brain microvascular endothelium has been shown to contribute to the pathophysiology of cerebral malaria. Recent studies reported increased levels of von Willebrand factor (VWF) and reduced activity of VWF-cleaving protease, ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13), in patients with cerebral malaria. Association of six single nucleotide polymorphisms (SNPs) of the ADAMTS13 gene with cerebral malaria was examined in 708 Thai patients with P. falciparum malaria. Among six SNPs, the derived allele of a SNP located in intron 28, rs4962153-A, was significantly associated with protection against cerebral malaria when 115 cerebral malaria patients were compared with 367 mild malaria patients (Fisher's exact P-value = 0.0057; OR = 0.27; 95% CI = 0.096-0.76). Significant association was also detected between 115 cerebral malaria and 593 non-cerebral malaria (226 non-cerebral severe malaria and 367 mild malaria) patients (Fisher's exact P-value = 0.012; OR = 0.30; 95% CI = 0.11-0.83). Excessive adhesion of PRBCs to the platelet-decorated ultra-large VWF (ULVWF) appears to enhance the sequestration of PRBCs to cerebral microvascular endothelium. The genetic association observed in the present study implies that the regulation of platelet-decorated ULVWF strings by ADAMTS13 may play a role in the development of cerebral malaria.Malaria Journal 12/2011; 10(1):366. DOI:10.1186/1475-2875-10-366 · 3.11 Impact Factor
Article: Comparative study of heavy metal and pathogenic bacterial contamination in sludge and manure in biogas and non-biogas swine farms. Journal of Environmental Sciences, 23, 991-997[Show abstract] [Hide abstract]
ABSTRACT: The objective of this study is to determine and compare the heavy metal (Zn, Cu, Cd, Pb) and bacterial (E. coli, coliform and Salmonella spp.) contamination between swine farms utilizing biogas and non-biogas systems in the central part of Thailand. Results showed that average levels of E. coli, coliform, BOD, COD, Zn, Cu and Pb in sludge from the post-biogas pond were higher than the standard limits. Moreover, the levels of E. coli, coliform, Cd and Pb were also higher than the standard limits for dry manure. The levels of E. coli, coliform and BOD on biogas farms were lower than on non-biogas farms. Following isolation of Salmonella spp., it was found that Salmonella serovars Rissen was the most abundant at 18.46% (12/65), followed by Anatum 12.31% (8/65), and Kedougou 9.23% (6/65). The pathogenic strains of Salmonella serovars Paratyphi B var. java and Typhimurium were present in equal amounts at 4.62% (3/65) in samples from all swine farms. This study revealed that significant reduction in E. coli and coliform levels in sludge from covered lagoon biogas systems on swine farms. The presence of Salmonella as well as Cd and Pb, in significant amount in dry manure, suggests that there is a high probability of environmental contamination if it is used for agricultural purposes. Thus, careful waste and manure disposal from swine farms and the regular monitoring of wastewater is strongly recommended to ensure the safety of humans, other animals and the environment.Journal of Environmental Sciences 06/2011; 23(6):991-7. DOI:10.1016/S1001-0742(10)60484-6 · 2.00 Impact Factor
Article: A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population[Show abstract] [Hide abstract]
ABSTRACT: Interleukin-12 (IL-12), a heterodimeric cytokine composed of p35 and p40 subunits, has been thought to play an important role in the pathogenesis of malaria. The IL-12p40 subunit is encoded by the IL12B gene. An IL12B promoter allele, CTCTAA, at rs17860508 has been reported to be associated with susceptibility to cerebral malaria in African populations. However, this association has not so far been replicated in non-African populations. To examine whether the CTCTAA allele is associated with susceptibility to cerebral malaria in Asian populations, 303 Thai patients with Plasmodium falciparum malaria (109 cerebral malaria and 194 mild malaria patients) were genotyped for rs17860508 by PCR-direct sequencing. The CTCTAA allele showed a significant association with susceptibility to cerebral malaria in the Thai population (allelic OR = 1.37; one sided P-value = 0.030). The existence of a significant association between the CTCTAA allele and susceptibility to cerebral malaria was confirmed in Southeast Asian population, which was previously reported in African populations.Malaria Journal 12/2009; 8(1, article 290):290. DOI:10.1186/1475-2875-8-290 · 3.11 Impact Factor
Article: Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria[Show abstract] [Hide abstract]
ABSTRACT: It has been previously demonstrated that a single nucleotide polymorphism (SNP) in the IL13 promoter region, IL13 -1055T>C (rs1800925), was associated with susceptibility to severe malaria in Thais. In the present study, fine association mapping for a cytokine gene cluster including IL4, IL5, and IL13 on chromosome 5q31 was conducted using the same malaria subjects to refine the region containing a primary variant or a haplotype susceptible to severe malaria. A total of 82 SNPs spanning 522 kb of the 5q31 region were analysed in 368 patients with Plasmodium falciparum malaria (203 mild malaria and 165 severe malaria patients). Only rs1881457 located in the promoter region of IL13, which is in linkage disequilibrium with rs1800925 (r2 = 0.73), showed a significant association with severe malaria after adjusting for multiple testing (P = 0.046 by permutation test). This SNP was in a haplotype block spanning 97 kb (from rs2069812 to rs2240032). The detected haplotype block contained the RAD50 gene and the promoter of IL13, but not the other genes. A haplotype block in which a primary polymorphism associated with severe malaria is likely to be encoded was identified in Thai malaria patients.Malaria Journal 10/2009; 8(1):232. DOI:10.1186/1475-2875-8-232 · 3.11 Impact Factor
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ABSTRACT: Interferon-gamma (IFN-gamma) has been suggested to play an important role in the pathogenesis of malaria. To examine possible association of the IFN-gamma receptor 1 (IFNGR1) polymorphisms with cerebral malaria, 312 adult patients with Plasmodium falciparum malaria (203 mild and 109 cerebral malaria patients) living in northwest Thailand were genotyped for six single nucleotide polymorphisms (SNPs) including -56T/C (rs2234711) and a microsatellite marker in IFNGR1. A case-control association analysis failed to detect significant association between the IFNGR1 polymorphisms and cerebral malaria, thus implying that the IFNGR1 polymorphism may not be a major genetic factor influencing the development of cerebral malaria in the Thai population. These data also provide useful information for future genetic studies of IFNG polymorphisms in Thai patients.Infection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseases 09/2009; 9(6):1406-9. DOI:10.1016/j.meegid.2009.08.004 · 3.02 Impact Factor
Article: A Functional Single‐Nucleotide Polymorphism in the CR1 Promoter Region Contributes to Protection against Cerebral Malaria[Show abstract] [Hide abstract]
ABSTRACT: Although the level of erythrocyte complement receptor type 1 (E-CR1) expression in patients with malaria has been extensively studied, whether the level of expression of E-CR1 is associated with severe malaria remains controversial. The present study examined a possible association of polymorphisms in the CR1 gene with the severity of malaria, and it evaluated the influence of the associated polymorphism on expression of E-CR1. Seventeen single-nucleotide polymorphisms in CR1 were genotyped in 477 Thai patients who had Plasmodium falciparum malaria (203 had mild malaria, 165 had noncerebral severe malaria, and 109 had cerebral malaria). The E-CR1 expression level was measured by flow cytometry in 24 healthy Thai subjects. The T allele of the reference single-nucleotide polymorphism rs9429942 in the CR1 promoter region was strongly associated with protection against cerebral malaria (2.2% of patients with mild malaria vs. 7.8% of patients with cerebral malaria; P = .0009; Bonferroni-adjusted Pc = .0306. The E-CR1 expression level was significantly higher in individuals with the TT genotype of rs9429942 than in individuals with the TC genotype of rs9429942 (P = .0282). We identified a CR1 promoter allele, associated with higher E-CR1 expression, that conferred protection against cerebral malaria. Previous studies have shown that the rate of clearance of immune complexes (ICs) from the circulation is related to the E-CR1 level. These results lead to the hypothesis that the clearance of ICs regulated by E-CR1 therefore plays a crucial role in the pathogenesis of cerebral malaria.The Journal of Infectious Diseases 11/2008; 198(12):1880-91. DOI:10.1086/593338 · 6.00 Impact Factor
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ABSTRACT: Hemoglobin E (HbE; beta26Glu --> Lys) is the most common variant of the beta-globin gene in Southeast Asia; it has been suggested that it confers resistance against Plasmodium falciparum malaria. In this study 306 adult patients with P. falciparum malaria (198 mild and 108 cerebral malaria patients) living in northwest Thailand were investigated to examine whether the HbE variant is associated with protection from cerebral malaria. Our results revealed that the sample allele frequency of HbE was not significantly different between mild (7.3%) and cerebral malaria (7.4%) patients. Thus, the HbA/HbE polymorphism would not be a major genetic factor influencing the onset of cerebral malaria in Thailand.Biochemical Genetics 10/2008; 46(11-12):708-11. DOI:10.1007/s10528-008-9185-3 · 0.87 Impact Factor
Article: Significant Association Between TIM1 Promoter Polymorphisms and Protection Against Cerebral Malaria in Thailand[Show abstract] [Hide abstract]
ABSTRACT: Although cerebral malaria is a major life-threatening complication of Plasmodium falciparum infection, its pathophysiology is not well understood. Prolonged activation of the T helper type 1 (Th1) response characterized by the production of pro-inflammatory cytokines such as IFN-gamma and TNF-alpha has been suggested to be responsible for immunopathological process leading to cerebral malaria unless they are downregulated by the anti-inflamatory cytokines produced by the Th2 response. The T cell immunoglobulin and mucin domain (TIM) family of proteins are cell surface proteins involved in regulating Th1 and Th2 immune responses. In this study, the possible association between the polymorphisms of TIM1, TIM3, and TIMD4 genes and the severity of malaria was examined in 478 adult Thai patients infected with P. falciparum malaria. The TIM1 promoter haplotype comprising three derived alleles, -1637A (rs7702919), -1549C (rs41297577) and -1454A (rs41297579), which were in complete linkage disequilibrium, was significantly associated with protection against cerebral malaria (OR = 0.41; 95% CI = 0.24-0.71; P= 0.0009). Allele-specific transcription quantification analysis revealed that the level of mRNA transcribed from TIM1 was higher for the protective promoter haplotype than for the other promoter haplotype (P= 0.004). Engagement with TIM1 in combination with T cell receptor stimulation induces anti-inflammatory Th2 cytokine production, which can protect the development of cerebral malaria caused by overproduction of pro-inflammatory Th1 cytokines. The present results suggest that the higher TIM1 expression associated with the protective TIM1 promoter haplotype confers protection against cerebral malaria.Annals of Human Genetics 06/2008; 72(Pt 3):327-36. DOI:10.1111/j.1469-1809.2007.00424.x · 2.21 Impact Factor
Article: R219K Polymorphism of ATP Binding Cassette Transporter A1 Related with Low HDL in Overweight/Obese Thai Males[Show abstract] [Hide abstract]
ABSTRACT: ATP binding cassette transporter A1 (ABCA1) plays a role in the initial stage of removing cholesterol from the body via cholesterol efflux. Mutations of this gene cause wide-ranging HDL deficiency, as evident in Tangier disease and familial hypoalphalipoproteinemia. The aim of this study was to elucidate whether the presence of ABCA1 gene polymorphism could be a risk factor for overweight/obesity. The presence of R219K and I883M genetic variant was determined by PCR-RFLP analysis in 112 overweight/obese and 117 control subjects of both sexes. Statistical analysis was performed to find an association between polymorphism and lipid data. Overweight/obese men carrying the mutant allele of R219K had lower level of HDL than the control (p = 0.006). However, no positive association was observed using bivariate logistic regression analysis. On the contrary, there was no difference in HDL level among genotypes in I883M polymorphism. Both polymorphisms appeared to be common in Thai ethnic groups. No difference was detected in genotype frequency between the two populations for both polymorphisms. Although the lower level of HDL in overweight/obese men carrying R219K in comparison to the control suggests the possible involvement of this gene with obesity, further investigations are needed to prove the influence of ABCA1 gene polymorphism on HDL level and to determine whether it could be a genetic determinant of obesity.Archives of Medical Research 12/2007; 38(8):834-8. DOI:10.1016/j.arcmed.2007.06.010 · 2.65 Impact Factor
Article: Significant association between TNF-? (TNF) promoter allele (?1031C, ?863C, and ?857C) and cerebral malaria in Thailand[Show abstract] [Hide abstract]
ABSTRACT: We examined a possible association of three single nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha (TNF) promoter -1031T>C (rs1799964), -863C>A (rs1800630), and -857C>T (rs1799724) with severe malaria in 466 adult patients having Plasmodium falciparum malaria in northwest Thailand. Four TNF promoter alleles comprising these three SNPs were detected in the studied population. The frequency of the TNF U04 allele designated -1031C, -863C, and -857C was found to be significantly greater in patients with cerebral malaria than in patients with mild malaria (12.6%, cerebral malaria vs 5.6%, mild malaria; odds ratio =2.5; P=0.002). The association of U04 with susceptibility to cerebral malaria was not caused by linkage disequilibrium with any specific HLA-B and -DRB1 alleles.Tissue Antigens 03/2007; 69(3):277-80. DOI:10.1111/j.1399-0039.2006.00756.x · 2.14 Impact Factor
Article: The genotypes of GYPA and GYPB carrying the MNSs antigens are not associated with cerebral malaria.[Show abstract] [Hide abstract]
ABSTRACT: Plasmodium falciparum invades erythrocytes via several routes using different red blood cell receptors that include glycophorin A (GYPA) and glycophorin B (GYPB). GYPA has two codominant alleles, i.e., M and N, that correspond to the M and N antigens, which differ by two amino acids (S1L, G5E); the codominant alleles of GYPB, i.e., S and s, correspond to the S and s antigens, which differ by a single amino acid (T29M). If these antigens influence the efficiency of erythrocyte invasion by malaria parasites, the MNSs phenotype may be associated with the severity of malaria. To examine this, the GYPA and GYPB genotypes carrying the MNSs antigens were analyzed in 109 and 203 Thai patients with cerebral malaria and mild malaria, respectively. Neither the genotype nor allele frequencies at each locus were statistically different between the cerebral and mild malaria patients. Thus, we conclude that the MNSs antigens do not reveal the difference in susceptibility to cerebral malaria.Journal of Human Genetics 02/2007; 52(5):476-9. DOI:10.1007/s10038-007-0133-6 · 2.46 Impact Factor
Article: Monocyte chemoattractant protein 1 (MCP-1) gene polymorphism is not associated with severe and cerebral malaria in Thailand[Show abstract] [Hide abstract]
ABSTRACT: The pathogenesis of cerebral malaria from Plasmodium falciparum infection is thought to involve inflammation of the central nervous system. Since monocyte chemoattractant protein 1 (MCP-1) is a chemokine strongly involved in the inflammatory process, we here study MCP-1 gene polymorphisms in association with severe or cerebral malaria in Thailand. Malaria patients in the northwest of Thailand were grouped into mild (n=206), severe (165), and cerebral (110) malaria case groups. Five single nucleotide polymorphisms (SNPs) in the promoter (-2518A/G, -2348G/C, -2158C/T, -2076A/T, and -2072T/C), and 1 SNP in intron 1 (764C/G) were analyzed by PCR-RFLP, PCR-SSP, or direct sequencing. The SNP -2158 was a novel polymorphism found in this study. For all SNPs, genotype and allele frequencies were not significantly different between mild and severe or mild and cerebral malaria. Strong linkage disequilibrium was found among 4 SNPs (-2518A/G, -2348G/C, -2076A/T, and 764C/G), resulting in 4 major estimated haplotypes. The most common haplotype was GGAC. The results indicated that MCP-1 gene polymorphisms were not associated with malaria severity, implying that MCP-1 was not a cause of malaria severity in this Thai population.Japanese journal of infectious diseases 09/2006; 59(4):239-44. · 1.16 Impact Factor
Article: A functional polymorphism in the IL1B gene promoter, IL-IB−31C>T, is not associated with cerebral malaria in Thailand[Show abstract] [Hide abstract]
ABSTRACT: IL-1beta and IL-1RA levels are higher in the serum of cerebral malaria patients than in patients with mild malaria. Recently, the level of IL1B expression was reported to be influenced by a polymorphism in the promoter of IL1, IL1B -31C>T. To examine whether polymorphisms in IL1B and IL1RA influence the susceptibility to cerebral malaria, IL1B -31C>T, IL1B 3953C>T, and IL1RA variable number of tandem repeat (VNTR) were analysed in 312 Thai patients with malaria (109 cerebral malaria and 203 mild malaria patients). In this population, IL1B -31C>T and IL1RA VNTR were detected, while IL1B 3953C>T (i.e., IL1B 3953T) was not observed in the polymorphism screening for 32 patients. Further analyses for IL1B -31C>T and IL1RA VNTR in 110 cerebral malaria and 206 mild malaria patients showed no significant association of these polymorphisms with cerebral malaria. The present results suggest that IL1B -31C>T and IL1RA VNTR polymorphisms do not play a crucial role in susceptibility or resistance to cerebral malaria.Malaria Journal 08/2005; 4(1):38. DOI:10.1186/1475-2875-4-38 · 3.11 Impact Factor
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ABSTRACT: The high degree of polymorphism of human leukocyte antigen (HLA) genes has been suggested to result from natural selection against susceptibility to a variety of infectious pathogens, including malaria. HLA molecules are considered to play a crucial role in the defense of the host against malarial infection, and different HLA class I and class II alleles have been reported to be associated with reduced susceptibility to malaria or the severity of malaria in different populations. To test for associations between HLA alleles and the severity of malaria in a Thai population, polymorphisms of HLA-B and HLA-DRB1 genes were investigated in 472 adult patients in northwest Thailand with Plasmodium falciparum malaria. In this study, malaria patients were classified into three groups: mild malaria, non-cerebral severe malaria, and cerebral malaria. Our results revealed that the allele frequencies of HLA-B46, -B56, and -DRB1*1001 were statistically different between non-cerebral severe malaria and cerebral malaria (P = 0.005), between mild malaria and cerebral malaria (P = 0.032), and between mild malaria and non-cerebral malaria (P = 0.007). However, our results may be showing false positives due to multiple testing. Thus, further study with a larger sample size must be conducted to obtain conclusive evidence of the association of these HLA-B and DRB1 alleles with the severity of malaria in Thailand.Japanese journal of infectious diseases 03/2005; 58(1):25-8. · 1.16 Impact Factor
Article: Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Brittenham G. et al.. Strong linkage disequilibrium of a HbE variant with the (AT)9(T)5 repeat in the BP1 binding site upstream of the β-globin gene in the Thai population. J Hum Genet 50: 7-11[Show abstract] [Hide abstract]
ABSTRACT: A binding site for the repressor protein BP1, which contains a tandem (AT)x(T)y repeat, is located approximately 530 bp 5' to the human beta-globin gene (HBB). There is accumulating evidence that BP1 binds to the (AT)9(T)5 allele more strongly than to other alleles, thereby reducing the expression of HBB. In this study, we investigated polymorphisms in the (AT)x(T)y repeat in 57 individuals living in Thailand, including three homozygotes for the hemoglobin E variant (HbE; beta26Glu-->Lys), 22 heterozygotes, and 32 normal homozygotes. We found that (AT)9(T)5 and (AT)7(T)7 alleles were predominant in the studied population and that the HbE variant is in strong linkage disequilibrium with the (AT)9(T)5 allele, which can explain why the betaE chain is inefficiently synthesized compared to the normal betaA chain. Moreover, the mildness of the HbE disease compared to other hemoglobinopathies in Thai may be due, in part, to the presence of the (AT)9(T)5 repeat on the HbE chromosome. In addition, a novel (AC)n polymorphism adjacent to the (AT)x(T)y repeat (i.e., (AC)3(AT)7(T)5) was found through the variation screening in this study.Journal of Human Genetics 01/2005; 50(1):7-11. DOI:10.1007/s10038-004-0210-z · 2.46 Impact Factor
Top Journals
Mahidol University
Siayuthia, Bangkok, Thailand
- • Department of Social and Environmental Medicine
- • Department of Microbiology and Immunology
- • Faculty of Tropical Medicine


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Baristas for Book Passage Café and Wine Bar
Located inside Marin County's beloved Book Passage Bookstore in Corte Madera, Book Passage Café and Wine Bar is the perfect place to relax with a book and a pastry, catch up with a friend over a cup of locally roasted coffee, or grab a meal before an author event. In addition to daily breakfast, lunch, and dinner service, we frequently host luncheons, mixers, and various other unique events.
Book Passage Café and Wine Bar is seeking applicants for barista positions. Applicants must be able to work day shifts, weekends, and some nights. Pay scale starts at $10 per hour plus shared house tips (open to negotiated rate depending on experience). Passion for literature and farm-to-table cuisine a plus! Book Passage Café and Wine Bar offers opportunities for creativity and growth, making it a great place for up-and-coming hospitality interns to start building a resume. We are searching for an organized, detail-oriented team player with experience in both back and front of house roles. Assisting with orders, light cleaning, food preparation, and cuisine creation, are all integral duties in the position. Please include resume and cover letter when responding to this listing. EOE. Send resumes and cover letters to Vanessa Wahlstrom, firstname.lastname@example.com.
Bookstore Manager
Book Passage is searching for an experienced, dynamic Bookstore Manager to join our Corte Madera team!
With over 800 author events per year, two internationally acclaimed annual conferences, an exciting array of writing and language classes, and of course, a comprehensive selection of books on a wide variety of topics, Book Passage is one of the world's leading bookstores and a Bay Area institution. We are committed to our community, working with a number of local schools, universities, and non-profit organizations, and striving to inspire creativity and learning for Bay Area residents of all ages. To that end, Book Passage offers employees endless opportunities to develop new interests and skills, personally and professionally.
With our lively calendar of author events, writing and language classes, book clubs, and more, no two days at Book Passage are alike. In addition to embracing daily excitement and challenges, general responsibilities will include:
• Creating the retail staffing schedule
• Hiring and training new booksellers
• Building and managing enticing book displays
• Active bookselling
• Modeling best practices that reflect Book Passage's commitment to customer service
• Leading Shift Managers and providing them with clear expectations
• Acting as Shift Manager as needed
• Maintaining clear communication between front room and back room staff
• Organizing and implementing various daily and long-range projects
We are looking for independently motivated applicants with both leadership and bookselling experience. Qualified candidates will demonstrate:
• Strong leadership skills—You are excited to lead our dedicated booksellers with confidence and compassion.
• Customer service expertise—We've spent over thirty years building a loyal customer base through exceptional customer service. You are attentive, patient, respectful, and knowledgeable.
• Familiarity with HR principles—You are approachable, trustworthy, and go out of your way to make staff feel appreciated.
• Excellent organizational skills—You are detail-oriented, logical, and constantly thinking of ways to make systems as clear and efficient as possible.
• Flexibility—You are comfortable with change.
• A passion for books and retail bookselling—You live and breathe literature! You love books and make it your mission to spread that love to patrons, offering enthusiastic and thoughtful recommendations.
This position is full-time. Salary will be determined based on experience. Benefits include healthcare coverage and PTO. Please include a resume and cover letter when responding to this listing. EOE. Send resumes and cover letters to Leslie Berkler, email@example.com.
Cafe & Wine Bar Manager
About Book Passage Café and Wine Bar
Located inside Marin County's beloved Book Passage Bookstore in Corte Madera, Book Passage Café and Wine Bar is the perfect place to relax with a book and a pastry, catch up with a friend over a cup of locally roasted coffee, or grab a meal before an author event. In addition to daily breakfast, lunch, and dinner service, we frequently host luncheons, mixers, and various other unique events.
About the Café Manager
From avid readers to renowned authors, Book Passage Café and Wine Bar serves many of the Bay Area's most creative minds. We are looking for a Café Manager who will draw upon this creative energy to infuse the café with inspiration and originality. This position offers freedom to implement fresh ideas—our ideal candidate will welcome feedback from customers and staff alike to determine what's working and make improvements where they are needed. An upbeat, helpful, and collaborative attitude is a must. If you're an innovative, organized, and flexible thinker with a passion for food and books, we'd love to hear from you!
Description of Duties
• Maintain and improve upon existing operational and administrative procedures to maximize efficiency
• Develop menus
• Manage inventory and operational costs to meet projected monthly and yearly budgets
• Train new employees and ensure continued success of all staff
• Assign weekly staff schedules
• Establish and sustain positive, lasting relationships with both patrons and vendors
• Ensure that California Retail Food Code health and safety regulations are consistently met
• Troubleshoot and maintain open dialogue with Book Passage's owners and retail staff
• Daily responsibilities will include food preparation, inventory management, overseeing staff training and scheduling, and maintaining a clean and inviting café environment.
• Experience in the hospitality and food service industry
• Detail-oriented and organized
• Leadership experience--you know how to bring out the best in every member of your team
• Excellent people skills--must provide exceptional customer service and maintain relationships with local vendors
• Understanding of operational and administrative systems
• Basic understanding of accounting principles to support inventory and cost management duties
• Ability to take charge and think clearly in a fast-paced environment
• Experience with Microsoft Word and Excel
• Experience with POS systems
Full-time position. Benefits include healthcare coverage and PTO. Resume and cover letter required when responding to this job posting. Send resumes and cover letters to Karen West, firstname.lastname@example.com.
Book Passage has attracted some of the most exciting thinkers and writers of our time! We are a stimulating, engaging place to work where no two days are the same.
We provide equal employment opportunities regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability or Vietnam Veteran status. We are always reviewing resumes for retail positions. If interested in a retail position at either our Corte Madera or San Francisco locations, please send your cover letter and resume to:
Book Passage
ATTN: Melinda Peabody, Retail Manager
51 Tamal Vista Blvd., Corte Madera, CA 94925
Or email your cover letter and resume to Melinda Peabody at email@example.com.
We sometimes have other positions available at Book Passage. Above are the current job openings.
If you don't see any listed, that means we have no openings at the moment, but please keep checking back as positions do open up occassionally.


text: http://forum.xda-developers.com – i have 2 microsd 32gb just sitting here and i tried it on my streak running dsc 1.5. it can read the card but i cant flash rom using sytem recovery it just aborts the installation. im currently using 16gb which works perfect but i stil want to use the 32gb. i tried formatting my mmc many time but still no luck. any solutions?thanks (HowTos)


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Coimbra Day 2
... free" day so we surfaced late before setting off to walk around the old town. Portugal (and Spain for that matter) doesn't start to move until about 10 o' clock and sure enough from 10 onwards the shutters on the shop windows began to go up and the city showed signs of waking up.
We had a good look at the cork products and Sue bought a handbag and some gifts. So it was a laid back morning and early afternoon. We felt we should really do ...
... br>
Once settled in, Anna and Charlotte elected to visit the stately pool complex, Barbara rested (preparing for Fado, she claimed), while Jeff, K, and I drove into town to visit the university. The hill upon which the university and cathedrals (old and new) sit, is very steep, and navigating the van up there was a bit of a challenge. Classes were obviously in session as parking was at a premium, but we lucked upon someone leaving, and a ...
... the franchesina... Which is like a slaughtered menagerie on a plate in between 2 slices of bread covered in cheese , with a chickens period (egg) on top, for good luck?... See picture. Fortunately not all Portugese food is as assaulting to the vegetarian plight and we've has some amazing food namely from our favourite family restaurant Papavinhos. Papavinhos we discovered by chance after escaping being chased ...
Coimbra University - Hogwarts to Potter
Leaving Obidos we saw our first cork trees. Cork, almond and olive trees became a familiar part of the landscape as we moved north to Coimbra.
Coimbra was the birthplace of six Portuguese kings and the seat of Portugal's oldest university. The Romans found the city of Ammonium and an important Moorish center. In 1064 Ferdinand the Great of Castile captured the city. As the Portuguese drove the Moors ...
... get out at the top of the town at the University and then walk down and found the town and then back across a footbridge over the Mondego river to the Hotel. We go to the pool to recover from our hike. We have dinner at the hotel which is very good. We have reserved and are put at a table by a waiter. The restaurant manageress then comes over and says we have to move because the table we are at has been reserved for ...


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A New York Times article on Friday has ignited a political firestorm by revealing that the government secretly monitored -- without court approval -- international phone calls and e-mail messages that originated in the United States. Critics say that government eavesdropping on hundreds if not thousands of Americans is a violation of civil liberties.
President Bush, acknowledging that he approved the domestic spying, cited the need to protect the nation from terrorist threats ''This authorization is a vital tool in our war against the terrorists. It is critical to saving American lives." The president said that his war on terrorism is targeting not only "enemies across the world" but "terrorists here at home."
But critics called it a "shocking admission." A weekend Washington Post editorial stated: "Illegal government spying on Americans is a violation of individual liberties, whether conditions are troubled or not. Nobody with a real regard for the rule of law and the Constitution would have difficulty seeing that."
Do the ends justify the means?
The administration credited the domestic spying program with uncovering several terrorist plots, including one plot revealed in 2003 that involved destroying the Brooklyn Bridge. If having the government read your email potentially saves lives, is giving up that privacy too much to ask? Where do you draw the line on what the government can know about you? What harm is there in a program like this?
What do you have to hide?
Critics say that the president's approval of a program that allows spying on Americans conflicts with a U.S. law that says such surveillance must be court-approved. Bush said the program has been reviewed regularly by the nation's top legal authorities and targets only those people with "a clear link to these terrorist networks." Why should ordinary citizens -- with no ties to terrorists -- be concerned about this program? If you have nothing to hide, why worry?
Can we even talk about it?
President Bush blasted the publication of the article and said that "the unauthorized disclosure of this effort damages our national security and puts our citizens at risk. Revealing classified information is illegal, alerts our enemies and endangers our country." Should the press be allowed to alert us of potential government violations of civil liberties -- even if that alerts our enemies as well? What if the president acts to prevent stories like this from being published through censorship in defense of national security? Would you agree with that?
Who's watching the watchers?
The president admonished the press for publishing the story, saying the publication hurt the war on terror by letting the enemy know what we were doing. But critics say the president should have followed the established procedure and gone to the courts to get permission for wiretaps and surveillance. So who went too far in your opinion? Did the press recklessly publish information it shouldn't have? Or did the president abuse his power and violate the law by ignoring the courts and Congress?
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Has anyone transitioned to toddler bed yet? I am pregnant and its getting really uncomfortable to bend over the bar of the crib (plus I'm not even supposed to be lifting DD - yea right) so we were thinking of transforming the crib into the toddler bed now. DD can climb out if she really wanted to anyway. I was wondering if any one has any advice on how to do this with LO, how to get them to stay in bed, etc...? Any advice would be appreciated!
Big Girl Bed??
Married Chris 6/21/08
Gave birth to Kristin 2/10/11
Next babyGIRL due 6/25/13!!!
Comments (5)
We are in a crib and will be for a while, I hope. For us, when they are able to climb out, its time to switch. I am too scared of a broken leg from LOs trying to get out and falling.
We will keep dd in a crib until she starts showing signs of climbing out or is potty trained.
My toilet only flushes when its a full moon and my kids are behaving.
When we first started it I would sit at the foot of the bed until he fell asleep, just to make sure he would stay. Within a few days I could leave when he was drowsy and laying still but first I'd kiss him and say, "stay in bed, please." He never got out. Now, I can actually SEND him to bed at nap time and he'll go on his own and fall asleep. It's the craziest thing.
My ODS was a bit harder to teach but he's just a different kind of kid. I think you just have to be willing to either stay in the room or take them back to bed 100 times while they get used to it. Other than that it's actually really easy.
i just started puting Riley to bed in her toddler bed this weekend in hopes to free up the crib for baby sister. The first night i put her down, she went straight to sleep but woke up about 1:30 and i had to put her back down. i layed with her for a minute until she fell back asleep. Last night i put her to bed. when i left the room she cried for about a minute before falling asleep. she never tried to get out though and she slept all night. i tried to make her toddler bed as similar to her crib as i could. i took her sheet and blanket out of the crib and put it on her bed. i also took her two fisher price music/light thingys out of the crib and hung them on the rail of the bed. so far it has been pretty easy, but she has always been easy to put to bed.
Thanks for the tips, ladies! I think we will start it this week.
Married Chris 6/21/08
Gave birth to Kristin 2/10/11
Next babyGIRL due 6/25/13!!!