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OAKLAND, Calif. -- The U.S. Department of Homeland Security's Federal Emergency Management Agency (FEMA) authorized firefighting funds to help Arizona fight the Willow fire burning near the community of Payson in Yavapai and Gila counties. Michael D. Brown, under secretary of Homeland Security for Emergency Preparedness and Response, approved the request for federal fire management assistance at 12:35 p.m. today. The 23,000-acre fire, sparked by lightening, is threatening 6,000 people and 3,000 homes in Payson, Pine and Strawberry.
Financial Assistance
If and when individual assistance money is approved for this disaster, it will be displayed here. Information is updated every 24 hours.
Public Assistance - Dollars ApprovedPublic Assistance Definitions
Public Assistance (PA): Disaster grant assistance available for communities to quickly respond to and recover from major disasters or emergencies declared by the President
Emergency Work (Categories A-B): Work that must be performed to reduce or eliminate an immediate threat to life, protect public health and safety, and to protect improved property that is significantly threatened due to disasters or emergencies declared by the President
Permanent Work (Categories C-G): Work that is required to restore a damaged facility, through repair or restoration, to its pre-disaster design, function, and capacity in accordance with applicable codes and standards
*Dollars Approved: Assistance dollars approved but not necessarily disbursed.
*Dollars Obligated: Funds made available to the State via electronic transfer following FEMA's final review and approval of Public Assistance projects.
|Total Public Assistance Grants - Dollars Obligated*
|Emergency Work (Categories A-B) - Dollars Obligated*
|Permanent Work (Categories C-G) - Dollars Obligated*
|Total Amount


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By Judy Kurtz
Sen. McCain, 76, just returned from a high-profile trip to Syria. He tweeted a photo of himself (clad in a tux) posing at the nuptials with the newly wedded duo and the rest of his family, writing:
Wonderful day at my son Jack's wedding! instagram.com/p/aCgZTxyyyk/— John McCain (@SenJohnMcCain) June 2, 2013
Photo: Jack McCain poses with new bride Renee Swift and Sen. John McCain and his wife, Cindy. / Courtesy: Office of Sen. John McCain

subset: commoncrawl


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Port Dickson Hotels & Resorts
Where to Stay in Port Dickson
32km from Seremban, Port Dickson is Negeri Sembilan's best-known district. PD (as it is known to locals) is a port town/beach resort that attracts a growing number of visitors each week. From the Cape Rachado Forest Reserve – where avid bird watchers usually head – to Monkey Bay's beautiful coral and clear waters, PD has its fair share of natural attractions to tempt daytrip visitors. Perhaps this is because of its close proximity to Kuala Lumpur or the wide range of hotels (ranging from budget deals to luxury ventures) within the area. Whatever the case, weekends are a busy time for Port Dickson's hoteliers and locals will advise you to book a room in advance as the best hotels fill up fast during peak periods.
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|Perlis Hotels


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Publications (293)1508.53 Total impact
- Human Genetics 06/2015; 134(7). DOI:10.1007/s00439-015-1574-1 · 4.82 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Height is the result of many growth and development processes. Most of the genes associated with height are known to play a role in skeletal development. Single-nucleotide poly-morphisms in the SPAG17 gene have been associated with human height. However, it is not clear how this gene influences linear growth. Here we show that a targeted mutation in Spag17 leads to skeletal malformations. Hind limb length in mutants was significantlyPLoS ONE 05/2015; 10(5). DOI:10.1371/journal.pone.0125936 · 3.23 Impact Factor
Article: RC/BTB2 is essential for formation of primary cilia in mammalian cells: Rc/Btb2 is Essential for Ciliogenesis[Show abstract] [Hide abstract]
ABSTRACT: RC/BTB2 is a binding partner of sperm associated antigen 16S (SPAG16S), which is regulator of spermiogenesis in mice, a process during which sperm flagella are formed. The expression of Rc/btb2 is also regulated by multicilin, a protein that controls ciliogenesis. Given that mouse Rc/btb2 mRNA is not only expressed in tissues bearing motile cilia, but also in tissues without motile cilia, we investigated whether RC/BTB2 plays a role in the general process of ciliogenesis by studying two somatic cells lines that have primary cilia, NIH3T3 and IMCD3. We discovered that the subcellular localization of RT/BTB2 in the NIH3T3 and IMCD3 cells encompasses the pathway for ciliogenesis. RC/BTB2 was found in the Golgi bodies and centrosomes, two key structures essential for normal ciliogenesis. Knockdown of Rc/btb2 gene expression in these cell lines disrupted ciliogenesis. The percentage of cells with primary cilia was significantly reduced in stable cell lines transduced with specific Rc/btb2 shRNA viruses compared to the control cells. When cilia were formed in the knockdown cells, they were significantly shorter than those in the control cells. Knockdown of Rc/btb2 expression did not affect cell proliferation and the cell cycle. Exogenous expression of RC/BTB2 in these stable knockdown cells restored ciliogenesis. These findings suggest that RC/BTB2 is a necessary component of the process of formation of primary cilia in somatic cells, perhaps through the transportation of cargos from Golgi bodies to centrosomes for cilia assembling. This article is protected by copyright. All rights reserved. © 2015 Wiley Periodicals, Inc.Cytoskeleton 03/2015; 72(4). DOI:10.1002/cm.21214 · 3.12 Impact Factor
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ABSTRACT: A key event in the process of spermiogenesis is the formation of the flagella, which enables sperm to reach eggs for fertilization. Yeast two-hybrid studies revealed that meiosis-expressed gene 1 (MEIG1) and Parkin co-regulated gene (PACRG) interact, and that sperm-associated antigen 16, which encodes an axoneme central apparatus protein, is also a binding partner of MEIG1. In spermatocytes of wild-type mice, MEIG1 is expressed in the whole germ cell bodies, but the protein migrates to the manchette, a unique structure at the base of elongating spermatid that directs formation of the flagella. In the elongating spermatids of wild-type mice, PACRG colocalizes with α-tubulin, a marker for the manchette, whereas this localization was not changed in the few remaining elongating spermatids of Meig1-deficient mice. In addition, MEIG1 no longer localizes to the manchette in the remaining elongating spermatids of Pacrg-deficient mice, indicating that PACRG recruits MEIG1 to the manchette. PACRG is not stable in mammalian cells, but can be stabilized by MEIG1 or by inhibition of proteasome function. SPAG16L is present in the spermatocyte cytoplasm of wild-type mice, and in the manchette of elongating spermatids, but in the Meig1 or Pacrg-deficient mice, SPAG16L no longer localizes to the manchette. By contrast, MEIG1 and PACRG are still present in the manchette of Spag16L-deficient mice, indicating that SPAG16L is a downstream partner of these two proteins. Together, our studies demonstrate that MEIG1/PACRG forms a complex in the manchette and that this complex is necessary to transport cargos, such as SPAG16L, to build the sperm flagella. © 2015. Published by The Company of Biologists Ltd.Development 03/2015; 142(5):921-30. DOI:10.1242/dev.119834 · 6.46 Impact Factor
Article: [172-POS]: Comparative expression profiling of endoplasmic reticulum aminopeptidase 2 and human leukocyte antigen-C expression in choriocarcinoma cell lines.[Show abstract] [Hide abstract]
ABSTRACT: Proper regulation of human leukocyte antigen-C (HLA-C) expression on trophoblast cells is essential for the immunological privilege of these cells. Endoplasmic reticulum aminopeptidase 2 (ERAP2) is known to trim antigenic peptide precursors for loading onto HLA. Altered expression of the ERAP2 could play a critical role in shaping HLA-C expression and antigen presentation, but their relationships have not been defined. We examined the genotype and expression levels of ERAP2 and HLA-C in several choriocarcinoma cell lines (BeWo, JAr, and JEG-3) by allelic discrimination qPCR, Western blotting and immunocytochemistry. Additionally, expression profiling of untreated versus gamma-interferon (IFN-γ, 20ng/ml)-treated cells was performed. Lastly, to determine if there is a relationship between ERAP2 and HLA-C expression levels, transfection of major and minor allele ERAP2 variants was performed. JAr cells were homozygous for the rs2248374 minor A allele, and express ERAP2 protein. BeWo and JEG-3 cells are homozygous for ERAP2 genetic variant (major G allele of SNP rs2248374) that causes non-sense mediated RNA decay, and thus lack ERAP2 protein expression. Interestingly, BeWo and JEG-3 cells express HLA-C, whereas, JAr cells do not. IFN-γ treatment of BeWo and JEG-3 cells increased HLA-C expression by 2-fold (p=0.0037) and 3-fold (p=0.0446) above control levels, respectively, but ERAP2 remained undetectable. In contrast, JAr cells treated with IFN-γ had increased ERAP2 protein expression by 2-fold (p=0.003), but had no effect on HLA-C expression. Transfection of JEG-3 cells (ERAP2 null) with ERAP2 plasmids with the SNP rs2549782, encoding an amino acid substitution (N392K) that alters substrate specificities and antigen presentation, revealed that the different ERAP2 isoforms do not affect the expression level of HLA-C. Our observations suggest that the expression patterns of ERAP2 and HLA-C allow choriocarcinoma cells to escape immune surveillance. E.D. Lee: None. S. Brockett: None. D. Hilliard: None. M.E. Teves: None. R. Ramus: None. J.F. Strauss: None. Copyright © 2014.01/2015; 5(1):88. DOI:10.1016/j.preghy.2014.10.178
Article: Identification of a gene in Mycoplasma hominis associated with preterm birth and microbial burden in intraamniotic infection[Show abstract] [Hide abstract]
ABSTRACT: Microbial invasion of the amniotic cavity is associated with spontaneous preterm labor and adverse pregnancy outcome and Mycoplasma hominis is often present. However, the pathogenic process by which M. hominis invades the amniotic cavity and gestational tissues, often resulting in chorioamnionitis and preterm birth, remains unknown. We hypothesized that strains of M. hominis vary genetically with regards to their potential to invade and colonize the amniotic cavity and placenta. We sequenced the entire genomes of two amniotic fluid isolates and a placental isolate of M. hominis from pregnancies that resulted in preterm births, and compared them to the previously sequenced genome of the Type strain PG21. We identified genes specific to the amniotic fluid/placental isolates. We then determined the microbial burden and the presence of these genes in another set of subjects, from whom samples of amniotic fluid had been collected and were positive for M. hominis. We identified two genes encoding surface-located membrane proteins (Lmp1 and Lmp-like) in the sequenced amniotic fluid/placental isolates that were severely truncated in PG21. We also identified, for the first time, a microbial gene of unknown function referred to in this study as gene of interest C (goiC), that was significantly associated with bacterial burden in amniotic fluid and the risk of preterm delivery in patients with preterm labor. A gene in M. hominis was identified that is significantly associated with colonization and/or infection of the upper reproductive tract during pregnancy and with preterm birth. Copyright © 2015 Elsevier Inc. All rights reserved.American Journal of Obstetrics and Gynecology 01/2015; 212(6). DOI:10.1016/j.ajog.2015.01.032 · 4.70 Impact Factor
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ABSTRACT: Mammalian SPAG6 protein is localized to the axoneme central apparatus, and it is required for normal flagella and cilia motility. Recent studies demonstrated that the protein also regulates ciliogenesis and cilia polarity in the epithelial cells of brain ventricles and trachea. Motile cilia are also present in the epithelial cells of the middle ear and Eustachian tubes, where the ciliary system participates in the movement of serous fluid and mucus in the middle ear. Cilia defects are associated with otitis media (OM), presumably due to an inability to efficiently transport fluid, mucus and particles including microorganisms. We investigated the potential role of SPAG6 in the middle ear and Eustachian tubes by studying mice with a targeted mutation in the Spag6 gene. SPAG6 is expressed in the ciliated cells of middle ear epithelial cells. The orientation of the ciliary basal feet was random in the middle ear epithelial cells of Spag6-deficient mice, and there was an associated disrupted localization of the planar cell polarity (PCP) protein, FZD6. These features are associated with disordered cilia orientation, confirmed by scanning electron microscopy, which leads to uncoordinated cilia beating. The Spag6 mutant mice were also prone to develop OM. However, there were no significant differences in bacterial populations, epithelial goblet cell density, mucin expression and Eustachian tube angle between the mutant and wild-type mice, suggesting that OM was due to accumulation of fluid and mucus secondary to the ciliary dysfunction. Our studies demonstrate a role for Spag6 in the pathogenesis of OM in mice, possibly through its role in the regulation of cilia/basal body polarity through the PCP-dependent mechanisms in the middle ear and Eustachian tubes.PLoS ONE 11/2014; 9(11):e112879. DOI:10.1371/journal.pone.0112879 · 3.23 Impact Factor
Article: Reassessing the Impact of Smoking on Preeclampsia/Eclampsia: Are There Age and Racial Differences?[Show abstract] [Hide abstract]
ABSTRACT: Objective To investigate the association between cigarette use during pregnancy and pregnancy-induced hypertension/preeclampsia/eclampsia (PIH) by maternal race/ethnicity and age. Methods This retrospective cohort study was based on the U.S. 2010 natality data. Our study sample included U.S. women who delivered singleton pregnancies between 20 and 44 weeks of gestation without major fetal anomalies in 2010 (n = 3,113,164). Multivariate logistic regression models were fit to estimate crude and adjusted odds ratios and the corresponding 95% confidence intervals. Results We observed that the association between maternal smoking and PIH varied by maternal race/ethnicity and age. Compared with non-smokers, reduced odds of PIH among pregnant smokers was only evident for non-Hispanic white and non-Hispanic American Indian women aged less than 35 years. Non-Hispanic Asian/Pacific Islander women who smoked during pregnancy had increased odds of PIH regardless of maternal age. Non-Hispanic white and non-Hispanic black women 35 years or older who smoked during pregnancy also had increased odds of PIH. Conclusion Our study findings suggest important differences by maternal race/ethnicity and age in the association between cigarette use during pregnancy and PIH. More research is needed to establish the biologic and social mechanisms that might explain the variations with maternal age and race/ethnicity that were observed in our study.PLoS ONE 10/2014; 9(10):e106446. DOI:10.1371/journal.pone.0106446 · 3.23 Impact Factor
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ABSTRACT: Humans are colonized by thousands of bacterial species, but it is difficult to assess the metabolic and pathogenic potential of the majority of these because they have yet to be cultured. Here, we characterize an uncultivated vaginal mycoplasma tightly associated with trichomoniasis that was previously known by its 16S rRNA sequence as "Mnola." In this study, the mycoplasma was found almost exclusively in women infected with the sexually transmitted pathogen Trichomonas vaginalis, but rarely observed in women with no diagnosed disease. The genomes of four strains of this species were reconstructed using metagenome sequencing and assembly of DNA from four discrete mid-vaginal samples, one of which was obtained from a pregnant woman with trichomoniasis who delivered prematurely. These bacteria harbor several putative virulence factors and display unique metabolic strategies. Genes encoding proteins with high similarity to potential virulence factors include two collagenases, a hemolysin, an O-sialoglycoprotein endopeptidase and a feoB-type ferrous iron transport system. We propose the name "Candidatus Mycoplasma girerdii" for this potential new pathogen.PLoS ONE 10/2014; 9(10):e110943. DOI:10.1371/journal.pone.0110943 · 3.23 Impact Factor
Article: Sperm-Associated Antigen 6 (SPAG6) Deficiency and Defects in Ciliogenesis and Cilia Function: Polarity, Density, and Beat[Show abstract] [Hide abstract]
ABSTRACT: SPAG6, an axoneme central apparatus protein, is essential for function of ependymal cell cilia and sperm flagella. A significant number of Spag6-deficient mice die with hydrocephalus, and surviving males are sterile because of sperm motility defects. In further exploring the ciliary dysfunction in Spag6-null mice, we discovered that cilia beat frequency was significantly reduced in tracheal epithelial cells, and that the beat was not synchronized. There was also a significant reduction in cilia density in both brain ependymal and trachea epithelial cells, and cilia arrays were disorganized. The orientation of basal feet, which determines the direction of axoneme orientation, was apparently random in Spag6-deficient mice, and there were reduced numbers of basal feet, consistent with reduced cilia density. The polarized epithelial cell morphology and distribution of intracellular mucin, α-tubulin, and the planar cell polarity protein, Vangl2, were lost in Spag6-deficient tracheal epithelial cells. Polarized epithelial cell morphology and polarized distribution of α-tubulin in tracheal epithelial cells was observed in one-week old wild-type mice, but not in the Spag6-deficient mice of the same age. Thus, the cilia and polarity defects appear prior to 7 days post-partum. These findings suggest that SPAG6 not only regulates cilia/flagellar motility, but that in its absence, ciliogenesis, axoneme orientation, and tracheal epithelial cell polarity are altered.PLoS ONE 10/2014; 9(10):e107271. DOI:10.1371/journal.pone.0107271 · 3.23 Impact Factor
Article: Comparative expression profiling of endoplasmic reticulum aminopeptidase 2 and human leukocyte antigen-c expression in choriocarcinoma cell linesPlacenta 09/2014; 35(9):A59. DOI:10.1016/j.placenta.2014.06.192 · 2.71 Impact Factor
Article: Differences in vaginal microbiome in African American women versus women of European ancestry[Show abstract] [Hide abstract]
ABSTRACT: Women of European ancestry are more likely to harbour a Lactobacillus-dominated microbiome, whereas African American women are more likely to exhibit a diverse microbial profile. African American women are also twice as likely to be diagnosed with bacterial vaginosis and are twice as likely to experience preterm birth. The objective of this study was to further characterize and contrast the vaginal microbial profiles in African American versus European ancestry women. Through the Vaginal Human Microbiome Project at Virginia Commonwealth University, 16S rRNA gene sequence analysis was used to compare the microbiomes of vaginal samples from 1268 African American women and 416 women of European ancestry. The results confirmed significant differences in the vaginal microbiomes of the two groups and identified several taxa relevant to these differences. Major community types were dominated by Gardnerella vaginalis and the uncultivated bacterial vaginosis-associated bacterium-1 (BVAB1) that were common among African Americans. Moreover, the prevalence of multiple bacterial taxa that are associated with microbial invasion of the amniotic cavity and preterm birth, including Mycoplasma, Gardnerella, Prevotella and Sneathia, differed between the two ethnic groups. We investigated the contributions of intrinsic and extrinsic factors, including pregnancy, body mass index, diet, smoking and alcohol use, number of sexual partners, and household income, to vaginal community composition. Ethnicity, pregnancy and alcohol use correlated significantly with the relative abundance of bacterial vaginosis-associated species. Trends between microbial profiles and smoking and number of sexual partners were observed; however, these associations were not statistically significant. These results support and extend previous findings that there are significant differences in the vaginal microbiome related to ethnicity and demonstrate that these differences are pronounced even in healthy women.Microbiology 07/2014; 160(Pt_10). DOI:10.1099/mic.0.081034-0 · 2.56 Impact Factor
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ABSTRACT: Polycystic ovary syndrome (PCOS), characterized by increased ovarian androgen biosynthesis, anovulation, and infertility, affects 5-7% of reproductive-age women. Genome-wide association studies identified PCOS candidate loci that were replicated in subsequent reports, including DENND1A, which encodes a protein associated with clathrin-coated pits where cell-surface receptors reside. However, these studies provided no information about functional roles for DENND1A in the pathogenesis of PCOS. DENND1A protein was located in the cytoplasm as well as nuclei of theca cells, suggesting a possible role in gene regulation. DENND1A immunostaining was more intense in the theca of PCOS ovaries. Using theca cells isolated and propagated from normal cycling and PCOS women, we found that DENND1A variant 2 (DENND1A.V2) protein and mRNA levels are increased in PCOS theca cells. Exosomal DENND1A.V2 RNA was significantly elevated in urine from PCOS women compared with normal cycling women. Forced overexpression of DENND1A.V2 in normal theca cells resulted in a PCOS phenotype of augmented CYP17A1 and CYP11A1 gene transcription, mRNA abundance, and androgen biosynthesis. Knock-down of DENND1A.V2 in PCOS theca cells reduced androgen biosynthesis and CYP17A1 and CYP11A1 gene transcription. An IgG specific to DENND1A.V2 also reduced androgen biosynthesis and CYP17 and CYP11A1 mRNA when added to the medium of cultured PCOS theca cells. We conclude that the PCOS candidate gene, DENND1A, plays a key role in the hyperandrogenemia associated with PCOS. These observations have both diagnostic and therapeutic implications for this common disorder.Proceedings of the National Academy of Sciences 03/2014; 111(15). DOI:10.1073/pnas.1400574111 · 9.67 Impact Factor
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ABSTRACT: In this Journal in 1972, 100 leaders in obstetrics and gynecology published a compelling statement that recognized the legalization of abortion in several states and anticipated the 1973 Supreme Court decision in Roe v Wade. They projected the numbers of legal abortions that likely would be required by women in the United States and described the role of the teaching hospital in meeting that responsibility. They wrote to express their concern for women's health in a new legal and medical era of reproductive control and to define the responsibilities of academic obstetrician-gynecologists. Forty years later, 100 professors examine the statement of their predecessors in light of medical advances and legal changes and suggest a further course of action for obstetrician gynecologists.Contraception 10/2013; 88(4):568-576. DOI:10.1016/j.contraception.2013.07.003 · 2.34 Impact Factor
Article: 2-Methoxyestradiol in the human corpus luteum throughout the luteal phase and its influence on lutein cell steroidogenesis and angiogenic activity[Show abstract] [Hide abstract]
ABSTRACT: To quantitate 2-methoxyestradiol (2-ME) in human corpus luteum (CL) of different ages and to determine the expression of cytochrome-P450-1A1 (CYP1A1) and catechol-O-methyl transferase (COMT) in CL and the action of 2-ME on P, vascular endothelial growth factor (VEGF) secretion, and luteal angiogenesis. Experimental study. University division of reproductive endocrinology. Twenty-four women of reproductive age. CL was collected from 15 women during the minilaparotomy for tubal sterilization. Granulosa lutein cells were harvested 36 hours after hCG administration in patients undergoing IVF. Levels of 2-ME were determined by high-performance liquid chromatography in CL. CYP1A1 and COMT were assessed by immunohistochemistry and Western blot. P and VEGF were measured by radioimmunoassay and ELISA. The angiogenic potential was analyzed using EA.hy926 cells. Plasma levels of E2 decreased in the late luteal phase in association with an increase in luteal tissue of 2-ME concentrations. Concomitantly, there was a significant reduction of angiogenic activity in late CL. There was no significant variation in CYP1A1 and COMT expression in all CL. In physiological doses, 2-ME inhibited basal VEGF by granulosa lutein cells and diminished the angiogenic activity in conditioned media but did not prevent P and VEGF production stimulated by hCG. These data suggest the participation of 2-ME in physiological luteolysis by reducing angiogenesis. However, 2-ME did not prevent in vitro hCG stimulation of P biosynthesis, providing a mechanism for CL rescue in the cycle of conception.Fertility and sterility 08/2013; 100(5). DOI:10.1016/j.fertnstert.2013.07.1980 · 4.59 Impact Factor
Article: A Novel ERAP2 Haplotype Structure in a Chilean Population: Implications for ERAP2 Protein Expression and Preeclampsia Risk[Show abstract] [Hide abstract]
ABSTRACT: Single nucleotide polymorphisms (SNPs) in the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene are associated with preeclampsia (PE) in different populations. rs2549782, a coding variant (N392K) that significantly affects substrate specificity, is in linkage disequilibrium (LD) with rs2248374, a marker SNP associated with ERAP2 protein expression in previously studied populations. As a result of non-sense mediated RNA decay, ERAP2 protein is not expressed from the rs2248374 G allele. We previously reported that the fetal rs2549782 minor G allele is associated with PE in African-Americans, but not Chileans. In this study, we found that rs2549782 was in LD with rs2248374 in African-Americans, but not in Chileans. The unexpected lack of strong LD in Chileans raised the possibility that rs2248374 could be associated with PE in the absence of an association with rs2549782. However, we found no significant association for this allele with PE in Chileans. Chileans homozygous for the rs2248374 G allele did not express 110 kDa ERAP2 protein, consistent with non-sense mediated RNA decay, and carriers of the rs2248374 A allele did. We conclude that the Chilean ERAP2 haplotype structure allows for the expression of the major T allele of rs2549782 encoding 392N, which could impact peptide trimming and antigen presentation. Our discovery of racial differences in genetic structure and association with PE reveal here-to-fore unrecognized complexity of the ERAP2 locus.07/2013; 1(2):98-107. DOI:10.1002/mgg3.13
Article: Fetal and Maternal Genes' Influence on Gestational Age in a Quantitative Genetic Analysis of 244,000 Swedish Births[Show abstract] [Hide abstract]
ABSTRACT: Although there is increasing evidence that genetic factors influence gestational age, it is unclear to what extent this is due to fetal and/or maternal genes. In this study, we apply a novel analytical model to estimate genetic and environmental contributions to pregnancy history records obtained from 165,952 Swedish families consisting of offspring of twins, full siblings, and half-siblings (1987-2008). Results indicated that fetal genetic factors explained 13.1% (95% confidence interval (CI): 6.8, 19.4) of the variation in gestational age at delivery, while maternal genetic factors accounted for 20.6% (95% CI: 18.1, 23.2). The largest contribution to differences in the timing of birth were environmental factors, of which 10.1% (95% CI: 7.0, 13.2) was due to factors shared by births of the same mother, and 56.2% (95% CI: 53.0, 59.4) was pregnancy specific. Similar models fit to the same data dichotomized at clinically meaningful thresholds (e.g., preterm birth) resulted in less stable parameter estimates, but the collective results supported a model of homogeneous genetic and environmental effects across the range of gestational age. Since environmental factors explained most differences in the timing of birth, genetic studies may benefit from understanding the specific effect of fetal and maternal genes in the context of these yet-unidentified factors.American journal of epidemiology 04/2013; 178(4). DOI:10.1093/aje/kwt005 · 5.23 Impact Factor
Conference Paper: Neutrophil Elastase in Term and Preterm Labor: A Novel and Potent Uterotonic Enzyme That Acts Via PAR 160th Annual Scientific Meeting of the; 03/2013
Conference Paper: Active MMP-1 Is Markedly Increased in Preterm Labor and Causes Uterine Contraction Via PAR160th Annual Scientific Meeting of the; 03/2013
Conference Paper: Epigenetic Regulation of Interleukin-17 Cytokines and Their Role in Neutrophil Infiltration in Preeclampsia60th Annual Scientific Meeting of the; 03/2013
Top Journals
Virginia Commonwealth University
Ричмонд, Virginia, United States
- • Department of Obstetrics and Gynecology
- • Department of Biochemistry and Molecular Biology
Johns Hopkins MedicineBaltimore, Maryland, United States
University of Arkansas at Little RockLittle Rock, Arkansas, United States
University of Santiago, ChileCiudadSantiago, Santiago Metropolitan, Chile
University of Pennsylvania
Philadelphia, Pennsylvania, United States
- • Department of Medicine
- • Center for Research on Reproduction and Women's Health
- • Department of Obstetrics and Gynecology
- • Division of Cardiothoracic Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
- • Department of Ophthalmology
- • Department of Obstetrics and Gynecology
- • Department of Pathology and Laboratory Medicine
Temple UniversityFiladelfia, Pennsylvania, United States
University of Texas at DallasRichardson, Texas, United States
Penn State Hershey Medical Center and Penn State College of Medicine
Hershey, Pennsylvania, United States
- Cellular and Molecular Physiology
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Spaghetti alla Carbonara
From EatingWell: October/November 2005
In this version, the eggs are cooked into a custardlike sauce. An extra step, yes, but the technique ensures food safety. To vary the vegetables, try green beans, asparagus or frozen peas (cook peas separately from pasta).
Makes: 6 servings, 1 cup each
Active Time:
Total Time:
Nutrition Profile
Diabetes appropriate | Low calorie | Low saturated fat | Heart healthy | Healthy weight | High fiber |View Our Nutrition Guidelines »
- 1 teaspoon extra-virgin olive oil
- 3 ounces thinly sliced prosciutto, or Canadian bacon, trimmed of fat and diced (1/2 cup)
- 2 cloves garlic, minced
- Pinch of crushed red pepper
- 3 large eggs, (pasteurized, if desired)
- 3/4 cup reduced-sodium chicken broth
- 3/4 teaspoon freshly ground pepper
- 12 ounces whole-wheat spaghetti, or linguine
- 8 ounces broccolini, (2 1/2 cups) or broccoli rabe (4 cups), stem ends trimmed, cut into 1/2-inch pieces
- 1/3 cup freshly grated Parmesan or Pecorino Romano cheese
- Salt, to taste
- Put a large pot of water on to boil for cooking pasta. Also bring about 1 inch of water to a gentle simmer in the bottom of a double boiler (see Equipment Tip).
- Heat oil in a medium nonstick skillet over medium heat. Add prosciutto (or Canadian bacon) and cook, stirring often, until heated through, about 2 minutes. Add garlic and crushed red pepper; cook, stirring, for 30 seconds. Remove from heat.
- Whisk eggs, broth and pepper in the top of the double boiler to combine. Set over the simmering water in the bottom of the double boiler and cook, whisking constantly in a slow, steady, figure-eight motion, until the sauce steams and thickens enough to coat a metal spoon, 5 to 7 minutes. The sauce may have a few small curdles. Remove the top pan from the heat and whisk the sauce rapidly so it does not continue to curdle.
- Meanwhile, cook pasta in the boiling water, stirring often, for 5 minutes. Drop in broccolini (or broccoli rabe) and cook until the pasta is tender but firm, 4 to 6 minutes more. Drain and place in a large bowl. Add the egg sauce, the prosciutto (or bacon) mixture and cheese; toss to coat well. Season with salt, if desired.
Tips & Notes
- Equipment tip: No double boiler? Improvise by setting a large stainless-steel bowl over a pan of simmering water.
Per serving: 307 calories; 7 g fat (2 g sat, 2 g mono); 121 mg cholesterol; 45 g carbohydrates; 0 g added sugars; 19 g protein; 8 g fiber; 528 mg sodium; 231 mg potassium.
Nutrition Bonus: Selenium (70% daily value), Vitamin C (60% dv), Fiber (30% dv), Calcium (15% dv), Iron (15% dv).
Carbohydrate Servings: 2 1/2
Exchanges: 2.5 starch, 1/2 vegetable, 1.5 medium-fat meat (mono)
Nutrition Note: Original Carbonara 574 calories, 27 grams total fat, 14 grams saturated fat, 2 grams fiber EW Carbonara 307 calories, 7 grams total fat, 2 grams saturated fat, 8 grams fiber
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Recipe Categories
- Total Time
- 45 minutes or less
- Ethnic/Regional
- Italian
- Mediterranean
- Servings
- 6
- Main Ingredient
- Pork
- Health & Diet Considerations
- Diabetes appropriate
- Low calorie
- Low saturated fat
- Heart healthy
- Healthy weight
- High fiber
- Preparation/ Technique
- Saute
- Meal/Course
- Dinner
- Holiday
- New Year's Eve
- Style/Theme
- Budget
- Comfort foods
- Kid-friendly
- Type of Dish
- Main dish, combination meal
- Main dish, Other
- Pasta
- Ease of Preparation
- Moderate
- Publication
- October/November 2005


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Hi, I want to create professional-looking blocks and I want to see the callbacks and programming of some blocks, as examples. It is possible?
Thanks in advance
No products are associated with this question.
Sure you can, right-click on the block and select "View Mask" - the option is disabled for blocks that are not masked. You can select "Look Under Mask" to see how the block has been implemented.
It's not clear what you mean by this. Can you specify an example from the Simulink library?
Opportunities for recent engineering grads.


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Bean, feta & herb dip
Cooking timePrep: 10 mins No cook
Skill levelEasy
ServingsServes 4
Dill, chive or mint (or a combination of all three!) really work in this creamy cannellini dip - a healthy snack
Nutrition and extra info
- Vegetarian
Nutrition info
Nutrition per serving
- kcalories
- 182
- protein
- 11g
- carbs
- 11g
- fat
- 10g
- saturates
- 7g
- fibre
- 1g
- sugar
- 2g
- salt
- 2.1g
Save to My Good Food
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- 400g can cannellini beans
- 200g feta cheese
- 1 tbsp lemon juice
- 1 garlic clove, crushed
- 3 tbsp chopped dill, mint or chives (or 1 tbsp each)
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Recipe from Good Food magazine, July 2012
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Obama is a White Sox poser. He grew up pulling for the A's.
He was a poser on that too. How can you claim to be a fan of either team and not say Frank Thomas or Reggie Jackson when asked for a favorite.
Carlos Lee to the Dodgers announced on MLB Network. Subject to Lee's right to block.
So Carlos Lee didn't want to go to LA but does want to go to Miami?
All about the money- specifically the lack of taxes
"It's not easy, but that's our job," Guillen said. "I don't think he should be blaming anybody. He should blame himself. We gave Gaby a lot of opportunities. The reason they made this move (is) obvious. We've not had much production from him, and in Carlos, we hope we've got more production. People don't make moves just to make moves."
Ozzie Guillen is the anti Davey Johnson. It is a crying shame he ever left the White Sox.
Well, it's not like he's saying anything that isn't true.
Howdy Rudy! Gino Tenace! Sal Bando! Vida Blue! Who the freak was the second baseman they wanted to bring up in the middle of the playoffs so they claimed their 2d baseman washurt whenhe wasn't? Manny Trillo?
Buster Olney @Buster_ESPNSources:There is no current discussion involving Crawford and Hanley Ramirez/Heath Bell. Was brought up briefly as concept,immediately died.
How are they going to afford Crawford? Aren't they already shedding salary
It was Crawford and a prospect. And clearly, they don't give a crap about money
Bob Nightengale @BNightengaleIf the #Marlins do decide they're out of it, Anibal Sanchez and Josh Johnson also will go. #Braves have expressed interest in Sanchez.
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No. 351, a 97-year-old Windsor streetcar, is finally home.
Hundreds of hours of footage. Three thousand historic photographs. Years of gathering interviews from local Second World War veterans.
A special exhibition, looking to shine a light on the forgotten women and vehicles of the First World War is coming to Fort Malden this weekend.
Even if you missed out on opening day, there are plenty of things to do at Fort Malden this summer. Here are The Windsor Star's top five.
In a narrow balcony packed with organ pipes, Larry Horwitz pulls back a curtain to reveal a bird's eye view of his grand ballroom.
Glen Cook was five or six years old when his grandfather would point out a black cemetery off Elmstead Road.
A half-century since it officially became our country's flag, the Red and White still manages to instill pride — even among teenage citizens.
From the Vault: A Photo History of Windsor has gone from local sensation to national bestseller.
Windsor's Community Museum needs your help to come up with the ABC's of Windsor's history.
Of all the ways to honour Tecumseh who died 201 years ago Sunday, artist Gordon Reeve said a sculpture of the Shawnee leader would have been the worst possible option.


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139:4 before a word is on my tongue. God knows David's thought before it is spoken. This is why we can pray to God silently in our thoughts. See "God Sees and Knows: Divine Omniscience" at Prov. 15:3.


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Larry and Rhondalyn Waddell of Elizabethtown announce the engagement and forthcoming marriage of their daughter, Lara Brianne Waddell, to David Colby Gibson, son of David and Cindy Gibson of Glendale.
The bride-to-be is a 2004 graduate of Union County High School and a 2010 graduate of Western Kentucky University. She holds a bachelor's degree in psychology and elementary education.
The prospective groom is a 2004 graduate of Central Hardin High School. He is employed with Flint Group.
By BOB WHITE
Former University of Kentucky basketball player Derrick Millar appeared in Elizabethtown's 9th Circuit Court Tuesday for what was scheduled to be a disposition hearing in a case accusing him of multiple felony thefts.
The charges stem from Millar's alleged sales of basketball tickets to Hardin County fans. He is accused of failing to deliver. Millar has been accused of like charges in about a dozen Kentucky counties, including a few where cases have ended in plea deals in exchange for guilty pleas.
By MARTY FINLEY
The status of grant money to support the construction of an amphitheater at City Park North in Radcliff is still unknown, but the city could have other options.
Mayor Sheila Enyart on Tuesday said the project is in limbo because the city has not yet secured the grant, but it may ask local businesses to sponsor construction of the amphitheater should the grant fall through.
City officials first considered applying for the grant in November when a resolution was brought before Radcliff City Council.
Pet of the Week This young male Hound mix named "Darwin" and this young female shorthair named "Jinx" are in need of loving homes. If you are interested in adopting them, contact Hardin County Animal Control at 769-3428 or visit 116 Nicholas St., Elizabethtown. Visit www.hcky.org/animalcontrol.asp for information. All dog adoptions are done by application proce
30 years ago, Sen. Joe Prather of Vine Grove was hospitalized at Hardin Memorial Hospital with diberticulosis, but planned to be in Frankfort for the opening of the 1980 General Assembly on Jan. 8.
At right top, Boy Scout Troop 233 assisted American Legion Post No. 113 in placing flags at Veteran's graves at the Elizabethtown City Cemetery in preparation for Memorial Day. At right bottom, Boy Scouts from Troop 233 carry their historical flag collection in the Memorial Day Parade in Elizabethtown. The Troop is sponsored by the Memorial United Methodist Church.
By Stan Lampe
Guest columnist
There has always been considerable historical controversy about the famous Midnight Ride of Paul Revere on April 18, 1775. In the outskirts of Boston, historians credit Revere with riding to Concord and warning American settlers that "The British are coming … The British are coming."
In the 235 years that have elapsed since that time, Great Britain has become one of the most loyal allies of the United States.
30 years ago, Eastview residents met to discuss an anti-sludge strategy; the concern was a storage site which was being constructed in Eastview to hold sludge brought from the Metropolitan Sewer District in Louisville. 20 years ago, U.S. Senator Mitch McConnell visited Elizabethtown, announcing his plans to seek re-election.
Jerry and Linda Curtsinger announce the engagement and forthcoming marriage of their daughter, Brooke N. Curtsinger, to Chris A. Blain, son of Connie Blain, father of Jordan Blain, all of Cecilia.
The wedding is at 2 p.m. June 19, 2010, at the home of the bride with a reception to follow.
Formal invitations have been sent.
Copyright © 2015
The News-Enterprise is your source for local news, sports, events and information in Elizabethtown, KY, Hardin County and the surrounding area.


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Tom Petty, Metallica, Bruce Springsteen, Billy Joel Among State Sales Champions
A new infographic illustrates the top-selling musicians in America by state of birth, with a number of familiar classic rock greats among those featured.
A new infographic illustrates the top-selling musicians in America by state of birth, with a number of familiar classic rock greats among those featured.
Tom Petty may credit country music with part of the Heartbreakers' signature sound, but he doesn't mean today's country music, which he recently called, among other things, "bad rock with a fiddle." Now Chris Stapleton, a country-music songwriter, has thrown down the gauntlet.
After hitting the pause button on sessions for their next record to focus on their 2013 summer tour, Tom Petty and the Heartbreakers are back at work in the studio.
Tom Petty and the Heartbreakers' show last night (June 8) at the Fonda Theatre in Los Angeles was shut down by fire marshals as a result of overcrowding.
Tom Petty and the Heartbreakers guitarist Mike Campbell admitted to Rolling Stone that he'd forgotten about some of the songs suggested for the group's current tour. Instead of just hauling out the usual hits, Petty and the Heartbreakers are digging deep into their 35-year-old catalog to fill out the set lists. And some of the cuts are so obscure, the guy who co-wrote some of them and played recorded of them can't even remember them.
Tom Petty is scheduled to spend much of the next month on the road with the Heartbreakers, including a multi-night stand at the Henry Ford Theatre in Los Angeles and a high-profile appearance at the Bonnaroo Music and Arts Festival in Tennessee. But fans familiar with Petty's regular set lists may not hear all the hits they're used to.
Tom Petty, John Fogerty and Jackson Browne joined Randy Newman onstage last night at the Rock and Roll Hall of Fame induction ceremony. The four veteran rockers, who all live in Los Angeles, opened the show at the city's Nokia Theater with a version of Newman's 1983 song 'I Love L.A.'
As if anyone really needed another reason to wish they were in Milwaukee during late June and early July, this year's Summerfest lineup looks like the classic rock party of a lifetime.
Tom Petty and the Heartbreakers have just announced the dates for their 2013 summer tour, and now Petty is discussing some of the group's plans for both those live performances and an upcoming album they plan to release later this year.
While Tom Petty's official 2013 touring calendar is still empty, it's been confirmed he'll headline the Hangout Music Festival in Gulf Shores, Ala. this spring. The full lineup for the festival was announced this week, with Kings of Leon named as a second headliner for the three-day festival.


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Kearney Cycles Streets of Galway 8K 2015 - Official Results/Prize-ListSubmitted by GCH info on Fri, 2015-08-14 15:53
The results and prize-winners for the Kearney Cycles Streets of Galway 8K road-race for 2015 have been declared official and are attached below. The decision of the race organising committee is final in all matters and no further correspondence can or will be entered into at this point.
Two PDF files of the final results have been generated, the first one sorted by finish (gross) time (and from which official results and prize-winners are calculated) and a second one sorted by chip (nett) time for information purposes only. A final list of individual category and team prize-winners is presented in the third attachment. Note - an adjustment has been applied to both F40 and F45 prize-categories to ensure that the correct finishers are credited with the appropriate prize in each case.
- Read more
- 1085 reads
Club ProfileSubmitted by GCH info on Sun, 2006-02-05 09:28
Galway City Harriers is an athletics club based in Galway city, Ireland, catering for senior and juvenile athletes. Founded in 1899, GCH has been to the forefront of athletics in Ireland throughout the 20th century and many famous athletes have represented both club and country in track and field, cross-country and road competitions.
- Read more
- 51516 reads
GCH ladies win at Galway Bay HalfSubmitted by JoanneOB on Thu, 2015-10-08 12:48
Conditions were perfect??? Not a sentence we've heard a lot of lately in the West for any sport but once in a while it all comes together and we are blessed with the ideal conditions to run. Saturday was one of those days………….
Three events took place this year……… 10k, Half Marathon and the addition of a Marathon saw approx. 2600 runners invade the prom with their own individual missions….to participate…….finish……PB…….win!!!
- Read more
- 299 reads
Successful day for GCH Juveniles at County X Country ChampsSubmitted by Ger on Sun, 2015-10-04 20:32
Jennifer Hughes took an early lead in the U14 race and finished strongly to win ahead of team mate Eimear Rowe. Ciara Dunne was 5th , the girls won the team competition with the help of Kara McCleane, Joanna Healy, Mairead Flynn, Ella Tomczak and Sinead Duggan.
- Read more
- 222 reads
Lost PropertySubmitted by Ger on Sat, 2015-10-03 12:15
We have a many items of sport clothing left behind by Juveniles after training during the 2015 track season in the Club Shed. Any items not claimed within the next two weeks will be donated to Charity as they are getting damp in the Shed. Please check the boxes at training.
- 77 reads
U7 - U13 Juvenille Training Cancelation NoticeSubmitted by Ger on Mon, 2015-09-28 11:06
There will be no training for U7s to U13s on Sunday 4th October and Sunday 10th October due to the County Cross Country Championships being held on those dates. The Closing date for entry for the Cross Country is Wednesday 30th Sept. Please notify any of the coaches asap if wish to enter and have not signed up already.
- 132 reads
Craughwell AC World Record AttemptSubmitted by Ger on Thu, 2015-09-24 21:43
Calling all GCH athletes to support Craughwell AC's Guinness World Record attempt on this Saturday 26th Sept in Dangan from 9am to 9pm. All levels of fitness welcome, just run 100m to take part in this 12 hour relay in conjunction with Mental & Physical Health Awareness day. Call in at anytime during Saturday there will be food, beverages and kids activites. Full details on the Craughwell AC website.
- 243 reads
September Training PlanSubmitted by JoanneOB on Mon, 2015-09-21 17:54
Please find September's Training plan attached which is geared towards the forthcoming Cross Country Season
Thanks to Matt Lockett and Brian Bruton for putting this together.
- 301 reads
Juvenile Training to resume on Sunday 13th SeptemberSubmitted by Ger on Tue, 2015-09-01 21:57
Due to the huge interest in Sunday's All Ireland Hurling final we are postponing our return to Juvenile training until Sunday 13th September. Looking forward to seeing you all back for the New Season.
- 452 reads
Track Training returns to 7.30pmSubmitted by JoanneOB on Tue, 2015-08-25 11:55
Track training will return tonight 25th August at 7.30pm at Dangan.
Full steam ahead for the forthcoming Cross Country Season with Matt Lockett and Marathon training with Jerome Debize!!
Warm up done and €2 at the gate.
- 345 reads


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Toei Animation Introduces 'Saint Seiya soul of gold'
Latest chapter of Toei's long-running series launches in Europe following its television and online debut.
Latest chapter of Toei's long-running series launches in Europe following its television and online debut.
Retail licensing deal with Viva Pictures Distribution includes 'Speed Racer,' 'Gaturro' and 'Lola & Virginia.'
2015 Pulcinella Awards to be held on April 18 in Venice at the 18th edition of Italian international animation festival Cartoons by the Bay.
Frederator acquires the rights to two popular preschool series -- 'Cloud Bread' and 'Pom Pom & Friends' -- from South Korea's Gangwon Information & Multimedia Corporation.
Corus Entertainment-owned TELETOON, BBC Worldwide and Radical Sheep team up on 'The Bagel And Becky Show' with showrunner Adam Rotstein of 'Inspector Gadget' fame.
Turner's premier kids channels to air more than 800 minutes of Mattel content including movies, features and short-form content for Barbie, Monster High, Hot Wheels and Max Steel across Latin America.
DHX Media to handle worldwide distribution for Gwen Stefani-inspired series produced by Moody Street Kids and Vision Animation for Network Ten.
Joint production company Hahn & m4e Productions developing 'Miko Miko,' 'Rejected Toys' and 'Siggi's Adventures' ahead of MIPTV.
French production and post-production company is known for producing the animation for the 'Asterix' series and 'Le Petit Prince.'
Kids' TV production and rights management company to collaborate with new digital platform TotallyTween on 26-episode, two-minute interactive series.
Brand-new Series, 'Noddy, Toyland Detective,' produced by Gaumont Animation in association with DreamWorks Animation Television, is set to debut on France Télévisions' France 5 in 2016.
Second series will see 52 new 11-minute episodes set for delivery in 2016, with 60-minute special set to follow in 2017; new 'Bob the Builder' shorts set to launch on YouTube in August 2015.
First proprietary preschool series for BBC Kids, "Nico Can Dance!" features traditional 2D animation and a live action host.
Former HIT Entertainment VP and CBeebies controller joins super-Indie Kids division to run The Foundation.
'Thunderbirds Are Go' is the new CGI-animated remake of the classic 1960s TV series co-produced between ITV Studios, New Zealand's Pukeko Pictures and Weta Workshop.
Mickey Mouse and his pals to star in 'Mickey and the Roadster Racers,' an action-packed animated series for preschoolers slated to debut in 2017 on Disney Junior.
Satirist, comedian and voice actor Stan Freberg voiced characters for the now-classic Warner Bros. Looney Tunes cartoons, working with the genre's king, Mel Blanc.
Rainbow announces that the eagerly anticipated third 'Winx Club' movie, 'The Mystery of the Abyss,' is set to hit cinemas in Greece throughout April!
Entertainment One Licensing reports strong retail sales and growing TV audiences for 'Peppa Pig' in Brazil with plans for experiential retail events that will drive growth in 2015.
Corus Entertainment-owned producer and distributor signs new licensees to iconic superhero franchise.
Boutique studio provides design, animation, VFX, editorial and compositing services to create unique cut-paper style imagery for 'Strong Roots' campaign for Boone County National Bank.
Animated comedy series set to screen at Annecy is produced by French studio Je Suis Bien Content in association with The Walt Disney Company EMEA and France Télévisions.
Thirteen-episode run of 'Dragons: Race to the Edge' will serve as a prequel to the second installment of the beloved 'How to Train Your Dragon' franchise.


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State of the Nation's Health Care 2011
Congress Challenged to Find Common Ground to Address Unprecedented Crisis in Our Health Care System
On January 27, 2011, at ACPs annual report on the state of the U.S. health care system we detailed the challenges faced by decreased access to health insurance coverage; decreased capacity in the health care workforce; and increased health care costs.
- Full report on the State of the Nations Health Care
- Remarks from ACP President J. Fred Ralston, Jr., MD, FACP
- Remarks from ACPs Senior Vice President of Government Affairs and Public Policy, Robert B. Doherty
- Background information on Expansion of Coverage
- Background information on Workforce Capacity
- Background information on Bending the Health Care Cost Curve
- Background information on Reforming the Medical Liability System
- Accompanying policy paper: How Can Our Nation Conserve and Distribute Health Care Resources Effectively and Efficiently?
- ACPs High-Value, Cost-Conscious Care Initiative
ACP Policies and Recommendations
This library is a collection of ACP's Clinical Guidelines, Ethical Guidelines, Policy Statements, and copies of testimony and letters to government and non-government officials.
The ACP Advocate Blog
September 11 reflections
- Friday, September 11, 2015
ACP to Medicare: Pay internists better!
- Wednesday, September 9, 2015
Why physicians must speak out against mass deportation of undocumented immigrants
- Wednesday, August 26, 2015
The ACP Advocate Newsletter
Putting Patients Before Paperwork, ACP on Physician-Assisted Suicide,
and Medicaid Expansion
October 2, 2015
ACP Advocacy Priorities, Telemedicine Usage, and Immigration Reform
September 18, 2015
- ICD-10 Implementation on the Horizon, ACP's Centennial, and 50 Years of
September 4, 2015


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GreatScopes: Microscopic Experiments &...
This page, from GreatScopes, offers a number of labs and experiments for teachers to incorporate microscope use into the classroom. The activities range from learning to prepare wet mounts and blood smears, to observing specific substances like yogurt and spider webs. There are also lessons on microscope use and care, and the use of lab journals in microscopy. Educators are invited to submit their own lessons for inclusion on the site.
Probability Lesson Starters and...
Simply defined, probability is the measure of the likeliness that an event will occur. Often represented as a number between 0 and 1, where 0 indicates...
Physics Girl is the brain child of MIT graduate Dianna Cowern, a self-professed "physics enthusiast and brainstorming wizard" who started shooting videos about...
While Britain's National Stem Centre website is loaded with resources related to science, technology, engineering, and math, the technology section is...
The Jet Propulsion Laboratory (JPL) at the California Institute of Technology has launched a fully revamped website with larger visuals and mobile-friendly...
The European Organization for Nuclear Research (CERN, from the French), which employees over two thousand staff members and has hosted more than ten thousand...
AMSER is a portal of educational resources and services built specifically for use by those in Community and Technical Colleges but free for anyone to use.
AMSER is funded by the National Science Foundation as part of the National Science Digital Library, and is being created by a team of project partners led by Internet Scout.
Make sure to check out AMSER's AMSER Science Reader Monthly. The AMSER SRM provides readers with a useful online collection of information about a particular topic related to applied math and science by combining freely available articles from popular journals with curriculum, learning objects, and web sites from the AMSER portal. The AMSER Science Reader Monthly is free to use in the classroom and is available here and can also be found under the About tab on the AMSER homepage.
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Select Local Merchants
The Drum Lab RocklinRead MoreIn 2005, The Drum Lab became Sacramento's first and only school of drumming. Since then, the Rocklin destination hasn't skipped a beat in its mission to elevate the standards of musical education. Voted one of the Best Places to Learn to Play Music by CBS Sacramento and the 2012 winner of Best Music Instruction from the KCRA 3 A-List, the school fuels students with the technical know-how and confidence to master their favorite songs, then instills them with the desire to expand their musical horizons. Based upon stylistic preference, students are paired with one of The Drum Lab's gifted instructors, who specialize in genres that include rock, jazz, R & B, hip-hop, Latin, and gospel. Once a week, in 30-minute sessions, future John Bonhams and lil' Gene Krupas learn to play in synchronicity with their instructor in acoustically crisp lab rooms fitted with two drum kits and a playback system with headphones. The school encourages students to beat their way out of comfort zones by periodically switching genres and instructors, helping them develop a comprehensive knowledge of drumming techniques and easing the nerves of insomniac rock drummers who fear waking up in a jazz quartet.2164 Sunset Boulevard,RocklinRocklin, CA US
One Stop GuitarRead MoreOne Stop Guitar instructors believe that learning the instrument should be fun and stress-free, so they cultivate a relaxed environment for their students as they begin or continue their musical journey. During lessons tailored toward helping each student reach their personal musical goals, six-string masters cover topics vital to blues, jazz, rock, metal, and pop. In addition to covering playing mechanics, the instructors can also offer their advice in songwriting, the music industry, and preparing for live shows, as well as discreetly swapping one's guitar for a paper-mache replica before emphatically smashing it.777 South Center StreetReno, NV US
Old Granite Street EateryRead MoreOne of the best-rated bars in Reno, Old Granite Street Eatery offers a trendy atmosphere with a fresh menu that features good burger. Not feeling the burger? They offer a menu with plenty of options. Expect perfect quality and a helpful waitstaff that's worth the visit. There's no specific recommended attire, so feel free to dress casually and comfortably. It's recommended that you should try the coffee, the chicken, or the salad, as each one is fantastic. In terms of the restaurant itself, it's been tabbed by the locals as a really solid option for large groups. Located in the heart of the Biggest Little City in the World, you won't walk away from Old Granite Street Eatery disappointed. The service, in general, is "friendly" and "wonderful," and food is "interesting" and "excellent." Also, its cocktails are known to be "great." Visitors to the restaurant have the ability to park nearby on the street.243 S Sierra StReno, NV US
Tim Lake Guitar InstructorRead MoreMusician Tim Lake has been playing music for 25 years. During lessons held at the Muzic Fuze store, Tim Lake helps students of all ages and experience levels express themselves instrumentally. Sight-reading, ear-training, and music theory are a few areas of specialty. As an added convenience, Tim keeps extra guitars in his studio for students who'd rather not lug around their own.777 South Center Street Room 7Reno, NV US
KinderCareRead MoreLike most parents, Cyndi R. doesn't like to take chances with her child's wellbeing. By the time her son was 13 months old, Cyndi had interviewed roughly 20 childcare providers—but she noticed something different when she walked into the local KinderCare. The staff here greeted every child by name and, as she peeked into each of the classrooms, Cyndi noticed engaged instructors leading one-on-one lessons. The center's Assistant Director even took the time to answer all of her questions, both before and after she decided to enroll her son. The thing is, this isn't a unique experience. KinderCare now has more than 1,700 centers, and parents across the country share similar thoughts on their local educators. To hear them tell it, it's the commitment of those teachers that makes all the difference. Twice a year, KinderCare hosts the largest early childhood teacher-training program in the country, and every center pursues national accreditation. All of this translates into the development of social, emotional, physical, and intellectual skills in infants and children up to 12 years old. That may seem like a lot of skills to entrust a daycare with, but KinderCare is more than just a daycare—in fact, it's better to think of it as a learning center. During daycare, kindergarten, and before- and after-school programs, KinderCare's educators lead activities that focus on six different areas, including math and science, language and literacy, and the art of opening a tricky juice box.8765 Sierra College BlvdGranite Bay, CA US
Lynn Greene PhotographyRead MoreThe team at Lynn Greene Photography has been snapping shots together since 2006—long enough to know that the most important part of their job is, by a happy coincidence, also the most fun. Each session begins with some lighthearted goofing around, establishing a playful tone that helps most people strike a relaxed pose. Their clients range from families to high-school seniors to sexy boudoir models, and they never fail to elicit a natural smile from any of the above. That said, they know when to get serious. They often help out corporate professionals looking for business headshots to separate them from the pack. Immediately after holding an in-studio or outdoor session, clients are invited to preview their images at the studio. While there, they can decide which pictures to preserve as prints, in coffee-table books, or on fake dollar bills.8789 Auburn Folsom RoadGranite Bay, CA US


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Region: Napa Valley, California
Varietal: Cabernet Sauvignon
Style: Big & Bold
Alcohol By Volume: 14.2%
Item no. 108238
The color of the wine is a beautiful garnet. On the nose is red plum and blackberry with notes of cedar. On the palate intense and layered with mocha, red currant and sweet spices, concentrated mid-palate and lingering finish.


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Medicines, Ethics, and Practice: A Guide for Pharmacists, Issue 23
Royal Pharmaceutical Society of Great Britain, 2000 - Pharmacy
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General Legal Requirements
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8 Health screening and health promotion
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Common terms and phrases
acetate POM acid POM Act l972 restrictions advice aloxiprin anthelmintic appropriate arsenic Pl Atropine BP GSL bromide POM Calcium capsules POM CD Anab POM CD Benz POM CD lnv POM CD No Register CD POM cent community pharmacists Controlled Drugs cream GSL cream POM Dexamethasone dispensed equivalent Erythromycin eye drops eye drops POM hydrochloride POM Hydrocortisone injection PML injection POM labelling macist maximum strength medicinal product methylated spirits oil GSL ointment Paracetamol patient person phar pharmacist pharmacy Poisons Act l972 poisons permitted Potassium practitioner Prednisolone preparations for external preparations GSL preparations PML preparations POM prescription prescription-only medicines professional Quinine Register POM requirements restrictions see poisons retail sale list sale or supply salts CD POM sodium POM sold solution POM Standards sulphate POM tablets CD tablets GSL tablets POM tartrate POM tion treatment vaccine PML vaccine POM veterinary drugs veterinary preparations Weleda


text: Lisa Rinna... Fake or Real? 3/24/2007 4:05 AM PDT BY TMZ STAFF Lisa Rinna at a benefit in 1994, and at an awards show in 2006. Get TMZ Breaking News alerts to your inbox Yes! Also send me "In Case You Missed It..." By clicking "Submit," you agree to the Privacy Policy and Terms of Use. >


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Stef Burns League takes to the road for a summer Italian tour this time featuring Stu Hamm on bass!
Stef said, "I met Stu back in 86, and we always wanted to do something together. Finally… almost 30 years later, we are finally doing it!"
A 7 city tour from the top to the bottom of Italy and back! With Juan van Emmerloot on drums.
Stu embarks on an East Coast tour with his band (Alex Skolnick and Joel taylor) also taking on some solo shows and workshops along the way.
Triple Bass Threat Tour kicks off 08/06/2015 in Augsburg.
For more information, email firstname.lastname@example.com]]>
(San Diego Session – June 21-26)
This course will give you the tools to tackle all musical styles including Funk, Rock, Pop, Blues, Jazz and much more using a broad range of technical skills on the bass including soloing, slap, walking, writing wicked bass lines, fretless technique, two hand tapping, and playing killer grooves. Topics will include maximizing your groove, interacting with the soloist (making them sound good), writing your own bass lines, total fretboard knowledge, learning all modes of the major and minor scales, soloing on any scale, riff development, pentatonics, symmetrical scales (diminished and whole tone), and much more. All topics will be applied to multiple musical styles, and is not limited to any one style, taste, or interest. This course will be designed for beginner to advanced students alike and will take your bass playing to the next level. Students in this course will enjoy having their mind blown by very special guest visits from international bass legends Stu Hamm and Rhonda Smith. Being a bass player is awesome, but hanging out with and learning from legends might be even better.
Get tickets here -> Book Tickets]]>
Check it out here
Framus & Warwick present: MASS MENTAL, a monster of a band reunites some major superstars for a very special concert! (Robert Trujillo – Bass Guitar (Metallica), Benji Webbe – Lead Vocals (Skindred), Armand Sabal-Lecco – Bass Guitar (Stanley Clarke), Ken Schalk – Drums (Candiria) with special guest: Whit Crane – Lead Vocals (Ugly Kid Joe)
Be there on September 6th, 2014 when superstars from all over the world gather at Framus & Warwick in Markneukirchen, Germany to celebrate with you an unforgettable day of concerts, Meet and Greets, Factory Tours and much, much more!
Gitarre & Bass magazine will open the day at 10:00. You can register for Factory Tours by sending an email to firstname.lastname@example.com. The spots will be full soon! So don´t wait for too long! You can shop at the flea market for blemished items or the Custom Shop for perfection and then have a BBQ.
Meet & Greets:
14:00 – 17:00 with some of the biggest players in the world!
Read more on: http://warwick.de/en/
On 23rd and 24th September, Stu will be teaching in London, UK.
Prior to the Carl Verheyen Tour kicking off you can catch Stu at The Bass Gallery, London for 1 to 1 bass lessons.
Don't miss out on this incredibly rare opportunity to learn from one of the great modern electric bass players.
Lessons last 60 minutes and must be booked in advance.
To enquire and book your lesson email firstname.lastname@example.com
The Bass Gallery
142 Royal College St, London
Tel: 020 7267 5458]]>


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AGC of America develops and delivers a number of educational programs that address key issues throughout the construction industry.
- Designed to be delivered in-seat, AGC Curricula offerings cover Building Information Modeling, Lean Construction, Supervisory Training, and Project Management. These courses can be held by AGC Chapters, within a construction firm or through other organizations.
- National programs on Project Management and Advanced Management provide an intensive learning experience for those looking to advance their knowledge and career.
- Safety Management training courses teach construction professionals what they need to know in the essential areas of safety and health.
- For those interested in learning from their desk, AGC offers educational Webinars throughout the year on a wide-range of industry topics, as well as Online OSHA courses and Safety Trained Supervisor exam preparation.
- AGC is an authorized provider of Continuing Education Units. Look to AGC to earn your CEUs for license renewals and career development.
No matter the size of your firm or the type of work you do, AGC of America has education and training programs designed for you.
Training, Education & Development Forum
AGC of America is committed to providing valuable resources and information in order to enhance performance and career development opportunities for individuals, member firms and the construction industry.
The Training, Education & Development (TED) Forum brings together AGC members and chapter staff by providing an opportunity for them to share information on industry trends and initiatives in the areas of construction education, training and workforce development. Forum members are also kept informed of any related AGC of America products and services. The Forum is led by a chair person and a steering committee of AGC members and chapter staff.
TED Forum members receive:
- A subscription to The Knowledge Source e-newsletter – distributed six times annually
- The ability to participate in an e-Forum discussion group focused on training, education and workforce development
- Information about AGC's professional development, curriculum, credentialing and workforce developing initiatives, products and services
- The opportunity to contribute through task forces or other leadership positions
Forum members can be kept informed and engage at the level that works best for them. Any AGC member or chapter staff interested in joining the Forum may contact Carly Trout.


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The North Park Theatre in Buffalo, New York is set to reopen on March 7, 2014, according to the theater's web site and a story published recently in The Buffalo News:
Hertel Avenue is about to get its crown jewel back.
The North Park Theatre announced Monday that its much-awaited reopening will take place March 7.
And when it does, longtime observers can't help but point out, this will not be your father's North Park Theatre. Some significant changes are in the offing for the North Buffalo movie house, apart from the extensive renovation that some insiders are putting in the neighborhood of $250,000
Click the Read link below to view the full article.
The theater opened in 1920 and Bill Dipson took over in 1967, but it closed June 6, 2013 when Dipson Theatres decided that it would no longer operate the movie theater. The president of the company said that they hadn't made money at the location in five years.
The new owners seem to be trying to bring in movies that haven't seen wide distribution, so it will be interesting to see if they will be able to attract a loyal audience with movies they have in their upcoming line-up, such as Girl on a Bicycle, Better Living Through Chemistry, and On My Way (Elle s'en va).
The Regal Elmwood Center 16 will be filling people's needs for mainstream movies, and the Dipson Amherst 3 and Screening Room Cinema & Cafe seem to be showing some non-mainstream fare that may present a challenge for the new theater, but the excitement is always high for the reopening of a historic theater and they should have a good chance to create an impression with moviegoers in the area.
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Casio Exilim EX-H50 pictures and hands-on
Casio used the Photokina 2012 camera trade show to launch another addition to its Exilim range, this time in the shape of the 24x optical zoom EX-H50.
Given the large zoom, this superzoom is more on the slender size. It's not a patch on the likes of the bulkier Canon SX50 HS, for example.
Many will find this small size an attractive part of the H50's design, but in the hand we were a little less impressed. It's just a bit plasticky, which, although not unexpected, lacks the finesse of some competitors.
That wouldn't be a big problem but this Exilim's autofocus isn't nearly as fast as some of its sister models, including the newly announced Exilim ZR1000 (which we thought was rather impressive).
The Casio EX-H50 is designed for those who just want to point, zoom and shoot by the look of things. The mode dial comes equipped with a number of basic modes, rather than offering full manual control, but this is fitting to its target audience.
The lens is a decent wide-angle, starting up at a 25mm equivalent and extending through to a significant 600mm equivalent. However the f/3.7-8.0 aperture means it'll be tough to shoot in low light at the full extent of the zoom. Fortunately there's sensor-shift stabilisation to help things out to some degree.
We don't think other superzoom makers are going to be quaking in their boots over this one, but if the price is held to a favourable level then we see no reason why the H50 won't do well. If the autofocus system was further improved then we'd feel a little more kind about this model, as it is it's just, well, a bit average.
DJI Osmo: Say goodbye to shaky 4K video (hands-on)
DJI Osmo is basically a pricey selfie stick that can shoot steady vids in 4K
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Light L16 Camera wants to beat DSLR with its 16 lenses and 52-megapixel shots
- DJI Osmo is basically a pricey selfie stick that can shoot steady vids in 4K
- DJI Osmo: Say goodbye to shaky 4K video (hands-on)
- Canon EOS 5DS review: Resolution revelation
- Light L16 Camera wants to beat DSLR with its 16 lenses and 52-megapixel shots
- Best GoPro: Which GoPro should you choose?
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- Win one of 10 PhotoBox Photo Books and five Retro Print sets
- X-Steady Electro handheld rig for action-cams and phones keeps vids silky smooth
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- Silver HP Spectre x360 will also get Skylake processors and same features as B&O limited edition
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'Good call quality, Good build quality and pleasant to hold chassis'
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Free Happy October Fall Printable
Download a free Happy October fall printable. Isn't it so pretty?!
Walmart: Current Deals
Here are the best deals at Walmart right now with thanks to I Heart the Mart for their help in compiling them. Please keep in mind that Walmart deals vary by region so the prices listed here will not be valid at all stores.
Birds Eye Steamfresh Flavorful Froze Veggies – $1.74
Redeem $0.75 Ibotta Offer
$0.99 after rebate
Hunt's Snack Pack Pudding 4pk – $1
Nabisco Go-Paks – $1
Buy 1 Hunt's Snack Pack Get 1 Nabisco Go-Pak printable
$0.50 after coupon
Always Discreet Liner – $2.72
Use $2/1 coupon from the 9/27 P&G insert
$0.72 after coupon
Suave Body Wash – $1.88
Use Buy One Get One Free coupon from the 9/27 RedPlum insert
$0.94 after coupon
Swiffer Duster Starter Kit – $2.97
Use $2/1 coupon from the 9/27 P&G insert
$0.97 after coupon
See the full list of Walmart deals here.
Did you find a great deal at Walmart? Just post about it on your blog and leave your link below. To make it easy for everyone to navigate quickly through the links, your link must link directly to your Walmart deals post. Links going to the homepage of your blog or any other part of your blog besides the direct link to your Walmart deals post will be deleted.
Shutterfly: 99 prints for $5.99 shipped!
Through October 5, 2015, you can get 99 prints from Shutterfly for just $5.99 shipped when you use coupon code TAKEAPEEK at checkout.
For more retail sales notifications and coupons, be sure to check out our Retail Sales Database.
5 Tips on How to Love a Spender
Guest post from Reelika of Financially Wise On Heels
Having a good relationship and communication with your partner is the key for a good life. Unfortunately, statistics show that many people get divorced due to financial issues. One of the problems may be that one person is a spender and the other is a saver.
If you and your significant other are at odds when it comes to financial issues, these 5 tips can help you better understand each other — and learn to love the spender in your life!
1. Listen, Share, and Communicate
Spenders think differently about money, saving, and spending. They are more impulsive and don't consider the differences between "wants" and "needs".
However, before you speak, listen carefully to what the spender has to share. Don't get emotional, but instead, share your thoughts and find the mutual language. Don't brag about how much you always save and don't be judgmental.
2. Understand the Spender's Background and the "Why"
How did the spender grow up? What were their family's saving and spending habits? What are the real "whys" he or she wants to spend so much?
Maybe it is a relief of stress, or finally having the opportunity to buy something? Spenders just love spending, no matter what the cost is. It can be frustrating, but always look for the real "why".
3. Create a Family Budget Plan Together
Having a family budget plan is crucial… and having the main spender involved is even more important. Create a plan together and discuss any splurges with the purpose of finding a solution.
Create a separate section for "free spending," so it becomes part of your budget plan already… and determine the amount that you are both able to spend without breaking your budget.
This relieves the stress for both of you as the spender can enjoy spending, and it is already part of your family's expenses.
4. Have Regular Family Meetings
Regular family meetings to discuss family finances can be very helpful. Don't only discuss spending, but also the possibilities for increasing the number of income streams.
Make sure you don't have the meeting after stressful day at work. This is never a good idea. Rather pick a weekend when you are not tired or rushing anywhere. It is important to make it a regular habit, otherwise the results are often only short term.
5. Balance Spending with Frugal Hacks
Spending and shopping are not necessarily bad habits. However, spending should be balanced with frugal hacks and/or savings.
One way to do it is to create a separate cash cushion for emergencies that potentially come up due to spending habits. Additionally, you should also consider cutting back on other items so the spender won't feel stressed about his or her spending.
Being responsible with finances is very important.
Following these five tips should help you find understanding and compromise with the spender in your life. Just remember to make plans and decisions together that are comfortable for BOTH of you.
How do you better understand spenders? Or if you are spender, how can others better understand you?
Reelika is an entrepreneur and the founder of Financially Wise On Heels. She is a happy wife and mom, Christian, financial management lover, and passionate about coaching. She provides inspiration, tools and resources to Moms to better plan, budget and manage their finances without sacrificing the needs and dreams of their families.
Walmart: Free plus overage Borden Cheese!
You can get a huge money maker deal on Borden Cheese at Walmart right now:
Buy 1 Borden Cheese Singles 8 ct package at $1.48
Use $4/1 Ibotta Deposit
Free plus overage after deposit
Thanks, Freebies For A Cause!