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Lee M. Nadler, MD
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Phone: (617) 632-3331
Fax: (617) 632-3541
Dana-Farber Cancer Institute
Phone: (617) 632-3331
Fax: (617) 632-3541
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Lee M. Nadler, MD
Dana-Farber Cancer Institute
- Virginia and D.K. Ludwig Professor of Medicine, Medicine, Harvard Medical School
- Chief, Medical Oncology, Brigham And Women's Hospital
- Senior Vice President, Experimental Medicine, Dana-Farber Cancer Institute
- Dean, Clinical and Translational Research, Harvard Catalyst - The Harvard Clinical and Translational Science Center
- Lymphoma and Myeloma, Member
- Institutional Representative for DFCI, Membership Committee
- Institutional Representative for DFCI, Executive Committee
- Member, Center Scientific Council
- Member, Clinical Science Coordinating Committee
- Deputy Associate Director, Clinical Sciences, Executive Committee
- Deputy Associate Director, Planning and Evaluation, Executive Committee
- Barbon CM, Davies JK, Voskertchian A, Kelner RH, Brennan LL, Nadler LM, Guinan EC. Alloanergization of human T cells results in expansion of alloantigen-specific CD8(+) CD28(-) suppressor cells. Am J Transplant 2014; 14:305-18. PubMed
- Davies JK, Barbon CM, Voskertchian A, Nadler LM, Guinan EC. Ex vivo alloanergization with belatacept: a strategy to selectively modulate alloresponses after transplantation. Cell Transplant 2013; 21:2047-61. PubMed
- Batista A, Barata JT, Raderschall E, Sallan SE, Carlesso N, Nadler LM, Cardoso AA. Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors. Exp Hematol 2011; 39:457-472.e3. PubMed
- Furman RR, Grossbard ML, Johnson JL, Pecora AL, Cassileth PA, Jung SH, Peterson BA, Nadler LM, Freedman A, Bayer RL, Bartlett NL, Hurd DD, Cheson BD, For The Cancer Leukemia Group B And Eastern Cooperative Oncology Group . A phase III study of anti-B4-blocked ricin as adjuvant therapy post-autologous bone marrow transplant: CALGB 9254. Leuk Lymphoma 2011; 52:587-96. PubMed
- Davies JK, Barbon CM, Voskertchian AR, Nadler LM, Guinan EC. Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade. 2011. PubMed
- Butler MO, Ansén S, Tanaka M, Imataki O, Berezovskaya A, Mooney MM, Metzler G, Milstein MI, Nadler LM, Hirano N. A panel of human cell-based artificial APC enables the expansion of long-lived antigen-specific CD4+ T cells restricted by prevalent HLA-DR alleles. Int Immunol 2010; 22:863-73. PubMed
- Davies JK, Singh H, Huls H, Yuk D, Lee DA, Kebriaei P, Champlin RE, Nadler LM, Guinan EC, Cooper LJ. Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies. Cancer Res 2010; 70:3915-24. PubMed
- Davies JK, Nadler LM, Guinan EC. Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation. Sci Transl Med 2010; 1:1ra3. PubMed
- Kondo E,Maecker B,Weihrauch MR,Wickenhauser C,Zeng W,Nadler LM,Schultze JL,von Bergwelt-Baildon MS. Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clin Cancer Res 2008; 14:6574-9. PubMed
- Ansen S,Butler MO,Berezovskaya A,Murray AP,Stevenson K,Nadler LM,Hirano N. Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21. Clin Cancer Res 2008; 14:6125-36. PubMed
- Davies JK,Yuk D,Nadler LM,Guinan EC. Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity. Transplantation 2008; 86:854-64. PubMed
- Davies JK,Gribben JG,Brennan LL,Yuk D,Nadler LM,Guinan EC. Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies. Blood 2008; 112:2232-41. PubMed
- Haining WN,Davies J,Kanzler H,Drury L,Brenn T,Evans J,Angelosanto J,Rivoli S,Russell K,George S,Sims P,Neuberg D,Li X,Kutok J,Morgan J,Wen P,Demetri G,Coffman RL,Nadler LM. CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans. Clin Cancer Res 2008; 14:5626-34. PubMed
- Haining WN, Ebert BL, Subrmanian A, Wherry EJ, Eichbaum Q, Evans JW, Mak R, Rivoli S, Pretz J, Angelosanto J, Smutko JS, Walker BD, Kaech SM, Ahmed R, Nadler LM, Golub TR. Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. J Immunol 2008; 181:1859-68. PubMed
- Haining WN,Angelosanto J,Brosnahan K,Ross K,Hahn C,Russell K,Drury L,Norton S,Nadler L,Stegmaier K. High-throughput gene expression profiling of memory differentiation in primary human T cells. BMC Immunol 2008; 9:44. PubMed
- Nadler LM, Roberts WC. Lee Marshall Nadler, MD: a conversation with the editor. Proc (Bayl Univ Med Cent) 2007; 20:381-9. PubMed
- Brown JR, Feng Y, Gribben JG, Neuberg D, Fisher DC, Mauch P, Nadler LM, Freedman AS. Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission. Biol Blood Marrow Transplant 2007; 13:1057-65. PubMed
- Rohatiner AZ, Nadler L, Davies AJ, Apostolidis J, Neuberg D, Matthews J, Gribben JG, Mauch PM, Lister TA, Freedman AS. Myeloablative Therapy With Autologous Bone Marrow Transplantation for Follicular Lymphoma at the Time of Second or Subsequent Remission: Long-Term Follow-Up. J Clin Oncol 2007; 25:2554-9. PubMed
- Butler MO, Lee JS, Ans. Long-Lived Antitumor CD8+ Lymphocytes for Adoptive Therapy Generated Using an Artificial Antigen-Presenting Cell. Clin Cancer Res 2007; 13:1857-1867. PubMed
- Hirano N, Butler M, Xia Z, Berezovskaya A, Murray AP, Ansen S, Kojima S, Nadler LM. Identification of an immunogenic CD8+ T cell epitope derived from {gamma}-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia. Blood 2006; 108:2662-8. PubMed
- Hirano N, Butler MO, Xia Z, Berezovskaya A, Murray AP, Ans. Efficient presentation of naturally processed HLA class I peptides by artificial antigen-presenting cells for the generation of effective antitumor responses. Clin Cancer Res 2006; 12:2967-75. PubMed
- Zander T, Yunes JA, Cardoso AA, Nadler LM. Rapid, reliable and inexpensive quality assessment of biotinylated cRNA. Braz J Med Biol Res 2006; 39:589-93. PubMed
- Veiga JP, Costa LF, Sallan SE, Nadler LM, Cardoso AA. Leukemia-stimulated bone marrow endothelium promotes leukemia cell survival. Exp Hematol 2006; 34:610-21. PubMed
- von Bergwelt-Baildon M, Shimabukuro-Vornhagen A, Popov A, Klein-Gonzalez N, Fiore F, Debey S, Draube A, Maecker B, Menezes I, Nadler LM, Schultze JL. CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. Blood 2005; 107:2786-9. PubMed
- Hirano N, Butler MO, Xia Z, Ans. Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity. Blood 2005; 107:1528-36. PubMed
- Costa LF, Balcells M, Edelman ER, Nadler LM, Cardoso AA. Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-kappaB. Blood 2005; 107:285-92. PubMed
- Gribben JG, Zahrieh D, Stephans K, Bartlett-Pandite L, Alyea EP, Fisher DC, Freedman AS, Mauch P, Schlossman R, Sequist LV, Soiffer RJ, Marshall B, Neuberg D, Ritz J, Nadler LM. Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia. Blood 2005; 106:4389-96. PubMed
- Maia S, Haining WN, Ans. Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia. Cancer Res 2005; 65:10050-8. PubMed
- Maecker B, von Bergwelt-Baildon MS, Anderson KS, Vonderheide RH, Anderson KC, Nadler LM, Schultze JL. Rare naturally occurring immune responses to three epitopes from the widely expressed tumour antigens hTERT and CYP1B1 in multiple myeloma patients. Clin Exp Immunol 2005; 141:558-62. PubMed
- Haining WN, Neuberg DS, Keczkemethy HL, Evans JW, Rivoli S, Gelman R, Rosenblatt HM, Shearer WT, Guenaga J, Douek DC, Silverman LB, Sallan SE, Guinan EC, Nadler LM. Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia. Blood 2005; 106:1749-54. PubMed
- Weihrauch MR, Ans. Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer. Clin Cancer Res 2005; 11:5993-6001. PubMed
- Gribben JG, Ryan DP, Boyajian R, Urban RG, Hedley ML, Beach K, Nealon P, Matulonis U, Campos S, Gilligan TD, Richardson PG, Marshall B, Neuberg D, Nadler LM. Unexpected association between induction of immunity to the universal tumor antigen CYP1B1 and response to next therapy. Clin Cancer Res 2005; 11:4430-6. PubMed
- Maecker B, von Bergwelt-Baildon MS, Sherr DH, Nadler LM, Schultze JL. Identification of a new HLA-A*0201-restricted cryptic epitope from CYP1B1. Int J Cancer 2005; 115:333-6. PubMed
- Brown JR, Yeckes H, Friedberg JW, Neuberg D, Kim H, Nadler LM, Freedman AS. Increasing incidence of late second malignancies after conditioning with cyclophosphamide and total-body irradiation and autologous bone marrow transplantation for non-Hodgkin's lymphoma. J Clin Oncol 2005; 23:2208-14. PubMed
- Haining WN, Cardoso AA, Keczkemethy HL, Fleming M, Neuberg D, DeAngelo DJ, Stone RM, Galinsky I, Silverman LB, Sallan SE, Nadler LM, Guinan EC. Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed acute lymphoblastic leukemia. Exp Hematol 2005; 33:286-94. PubMed
- Friedberg JW, Kim H, McCauley M, Hessel EM, Sims P, Fisher DC, Nadler LM, Coffman RL, Freedman AS. Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without significant toxicity. Blood 2004; 105:489-95. PubMed
- Hirano N, Butler MO, Guinan EC, Nadler LM, Kojima S. Presence of anti-kinectin and anti-PMS1 antibodies in Japanese aplastic anaemia patients. Br J Haematol 2005; 128:221-3. PubMed
- Barata JT, Keenan TD, Silva A, Nadler LM, Boussiotis VA, Cardoso AA. Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia. Haematol Hematol J 2004; 89:1459-67. PubMed
- Barata JT, Silva A, Brandao JG, Nadler LM, Cardoso AA, Boussiotis VA. Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells. J Exp Med 2004; 200:659-69. PubMed
- Barata JT, Boussiotis VA, Yunes JA, Ferrando AA, Moreau LA, Veiga JP, Sallan SE, Look AT, Nadler LM, Cardoso AA. IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL. Blood 2003; 103:1891-900. PubMed
- Brown JR, Gaudet G, Friedberg JW, Neuberg D, Mauch P, Kutok JL, Takvorian T, Fisher DC, Gribben JG, Kim H, Nadler LM, Freedman AS. Autologous bone marrow transplantation for marginal zone non-Hodgkin's lymphoma. Leuk Lymphoma 2004; 45:315-20. PubMed
- Vonderheide RH, Domchek SM, Schultze JL, George DJ, Hoar KM, Chen DY, Stephans KF, Masutomi K, Loda M, Xia Z, Anderson KS, Hahn WC, Nadler LM. Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin Cancer Res 2004; 10:828-39. PubMed
- Hirano N, Butler MO, Von Bergwelt-Baildon MS, Maecker B, Schultze JL, O'Connor KC, Schur PH, Kojima S, Guinan EC, Nadler LM. Autoantibodies frequently detected in patients with aplastic anemia. Blood 2003; 102:4567-75. PubMed
- Maecker B, Sherr DH, Vonderheide RH, von Bergwelt-Baildon MS, Hirano N, Anderson KS, Xia Z, Butler MO, Wucherpfennig KW, O'Hara C, Cole G, Kwak SS, Ramstedt U, Tomlinson AJ, Chicz RM, Nadler LM, Schultze JL. The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells. Blood 2003; 102:3287-94. PubMed
- Tzachanis D, Appleman LJ, Van Puijenbroek AA, Berezovskaya A, Nadler LM, Boussiotis VA. Differential localization and function of ADP-ribosylation factor-6 in anergic human T cells: a potential marker for their identification. J Immunol 2003; 171:1691-6. PubMed
- Maecker B, Anderson KS, von Bergwelt-Baildon MS, Weller E, Vonderheide RH, Richardson PG, Schlossman RL, Menezes IA, Xia Z, Munshi NC, Anderson KC, Nadler LM, Schultze JL. Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma. Br J Haematol 2003; 121:842-8. PubMed
- Mollick JA, Hodi FS, Soiffer RJ, Nadler LM, Dranoff G. MUC1-like tandem repeat proteins are broadly immunogenic in cancer patients. Cancer Immun 2003; 3:3. PubMed
- Grader-Beck T, van Puijenbroek AA, Nadler LM, Boussiotis VA. cAMP inhibits both Ras and Rap1 activation in primary human T lymphocytes, but only Ras inhibition correlates with blockade of cell cycle progression. Blood 2002; 101:998-1006. PubMed
- Nadler LM, Schultze JL. From genomics to cancer vaccines: patient-tailored or universal vaccines? Curr Opin Mol Ther 2003; 4:572-6. PubMed
- Scardino A, Gross DA, Alves P, Schultze JL, Graff-Dubois S, Faure O, Tourdot S, Chouaib S, Nadler LM, Lemonnier FA, Vonderheide RH, Cardoso AA, Kosmatopoulos K. HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy. J Immunol 2002; 168:5900-6. PubMed
- von Bergwelt-Baildon MS, Vonderheide RH, Maecker B, Hirano N, Anderson KS, Butler MO, Xia Z, Zeng WY, Wucherpfennig KW, Nadler LM, Schultze JL. Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application. Blood 2002; 99:3319-25. PubMed
- Appleman LJ, van Puijenbroek AA, Shu KM, Nadler LM, Boussiotis VA. CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells. J Immunol 2002; 168:2729-36. PubMed
- Tzachanis D, Berezovskaya A, Nadler LM, Boussiotis VA. Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses. Blood 2002; 99:1465-73. PubMed
- Tzachanis D, Freeman GJ, Hirano N, van Puijenbroek AA, Delfs MW, Berezovskaya A, Nadler LM, Boussiotis VA. Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells. Nat Immunol 2001; 2:1174-82. PubMed
- Vonderheide RH, Schultze JL, Anderson KS, Maecker B, Butler MO, Xia Z, Kuroda MJ, von Bergwelt-Baildon MS, Bedor MM, Hoar KM, Schnipper DR, Brooks MW, Letvin NL, Stephans KF, Wucherpfennig KW, Hahn WC, Nadler LM. Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals. Cancer Res 2001; 61:8366-70. PubMed
- Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, Nadler LM. Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase. Clin Cancer Res 2001; 7:3343-8. PubMed
- Vonderheide RH, Butler MO, Liu JF, Battle TE, Hirano N, Gribben JG, Frank DA, Schultze JL, Nadler LM. CD40 activation of carcinoma cells increases expression of adhesion and major histocompatibility molecules but fails to induce either CD80/CD86 expression or T cell alloreactivity. Int J Oncol 2001; 19:791-8. PubMed
- Schultze JL, Anderson KC, Gilleece MH, Gribben JG, Nadler LM. A pilot study of combined immunotherapy with autologous adoptive tumour-specific T-cell transfer, vaccination with CD40-activated malignant B cells and interleukin 2. Br J Haematol 2001; 113:455-60. PubMed
- Friedberg JW, Neuberg D, Monson E, Jallow H, Nadler LM, Freedman AS. The impact of external beam radiation therapy prior to autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma. Biol Blood Marrow Transplant 2001; 7:446-53. PubMed
- Robinson SN, Freedman AS, Neuberg DS, Nadler LM, Mauch PM. Loss of marrow reserve from dose-intensified chemotherapy results in impaired hematopoietic reconstitution after autologous transplantation: CD34(+), CD34(+)38(-), and week-6 CAFC assays predict poor engraftment. Exp Hematol 2001; 28:1325-33. PubMed
- Datta MW, Shahsafaei A, Nadler LM, Freeman GJ, Dorfman DM. Expression of MHC class II-associated invariant chain (Ii;CD74) in thymic epithelial neoplasms. Appl Immunohistochem Mol Morphol 2000; 8:210-5. PubMed
- Stripecke R, Cardoso AA, Pepper KA, Skelton DC, Yu XJ, Mascarenhas L, Weinberg KI, Nadler LM, Kohn DB. Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage- colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses. Blood 2000; 96:1317-26. PubMed
- Longo DL, Duffey PL, Gribben JG, Jaffe ES, Curti BD, Gause BL, Janik JE, Braman VM, Esseltine D, Wilson WH, Kaufman D, Wittes RE, Nadler LM, Urba WJ. Combination chemotherapy followed by an immunotoxin (anti-B4-blocked ricin) in patients with indolent lymphoma: results of a phase II study. Cancer J 2000; 6:146-50. PubMed
- Boussiotis VA, Freeman GJ, Taylor PA, Berezovskaya A, Grass I, Blazar BR, Nadler LM. p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. Nat Med 2000; 6:290-7. PubMed
- Cardoso AA, Veiga JP, Ghia P, Afonso HM, Haining WN, Sallan SE, Nadler LM. Adoptive T-cell therapy for B-cell acute lymphoblastic leukemia: preclinical studies. Blood 1999; 94:3531-40. PubMed
- Friedberg JW, Neuberg D, Stone RM, Alyea E, Jallow H, LaCasce A, Mauch PM, Gribben JG, Ritz J, Nadler LM, Soiffer RJ, Freedman AS. Outcome in patients with myelodysplastic syndrome after autologous bone marrow transplantation for non-Hodgkin's lymphoma. J Clin Oncol 1999; 17:3128-35. PubMed
- Guinan EC, Boussiotis VA, Neuberg D, Brennan LL, Hirano N, Nadler LM, Gribben JG. Transplantation of anergic histoincompatible bone marrow allografts. N Engl J Med 1999; 340:1704-14. PubMed
- Vonderheide RH, Hahn WC, Schultze JL, Nadler LM. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity 1999; 10:673-9. PubMed
- Freeman GJ, Cardoso AA, Boussiotis VA, Anumanthan A, Groves RW, Kupper TS, Clark EA, Nadler LM. The BB1 monoclonal antibody recognizes both cell surface CD74 (MHC class II-associated invariant chain) as well as B7-1 (CD80), resolving the question regarding a third CD28/CTLA-4 counterreceptor. J Immunol 1998; 161:2708-15. PubMed
- Ghia P, Boussiotis VA, Schultze JL, Cardoso AA, Dorfman DM, Gribben JG, Freedman AS, Nadler LM. Unbalanced expression of bcl-2 family proteins in follicular lymphoma: contribution of CD40 signaling in promoting survival. Blood 1998; 91:244-51. PubMed
- Schultze JL, Michalak S, Seamon MJ, Dranoff G, Jung K, Daley J, Delgado JC, Gribben JG, Nadler LM. CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy. J Clin Invest 1998; 100:2757-65. PubMed
- Dorfman DM, Schultze JL, Shahsafaei A, Michalak S, Gribben JG, Freeman GJ, Pinkus GS, Nadler LM. In vivo expression of B7-1 and B7-2 by follicular lymphoma cells can prevent induction of T-cell anergy but is insufficient to induce significant T-cell proliferation. Blood 1997; 90:4297-306. PubMed
- Andersen NS, Donovan JW, Borus JS, Poor CM, Neuberg D, Aster JC, Nadler LM, Freedman AS, Gribben JG. Failure of immunologic purging in mantle cell lymphoma assessed by polymerase chain reaction detection of minimal residual disease. Blood 1997; 90:4212-21. PubMed
- Boussiotis VA, Freeman GJ, Berezovskaya A, Barber DL, Nadler LM. Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science 1997; 278:124-8. PubMed
- Schultze JL, Seamon MJ, Michalak S, Gribben JG, Nadler LM. Autologous tumor infiltrating T cells cytotoxic for follicular lymphoma cells can be expanded in vitro. Blood 1997; 89:3806-16. PubMed
- Soiffer RJ, Fairclough D, Robertson M, Alyea E, Anderson K, Freedman A, Bartlett-Pandite L, Fisher D, Schlossman RL, Stone R, Murray C, Freeman A, Marcus K, Mauch P, Nadler L, Ritz J. CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission. Blood 1997; 89:3039-47. PubMed
- Boussiotis VA, Barber DL, Lee BJ, Gribben JG, Freeman GJ, Nadler LM. Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation. J Exp Med 1996; 184:365-76. PubMed
- Cardoso AA, Schultze JL, Boussiotis VA, Freeman GJ, Seamon MJ, Laszlo S, Billet A, Sallan SE, Gribben JG, Nadler LM. Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen. Blood 1996; 88:41-8. PubMed
- Gribben JG, Guinan EC, Boussiotis VA, Ke XY, Linsley L, Sieff C, Gray GS, Freeman GJ, Nadler LM. Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool. Blood 1996; 87:4887-93. PubMed
- Matulonis U, Dosiou C, Freeman G, Lamont C, Mauch P, Nadler LM, Griffin JD. B7-1 is superior to B7-2 costimulation in the induction and maintenance of T cell-mediated antileukemia immunity. Further evidence that B7-1 and B7-2 are functionally distinct. J Immunol 1996; 156:1126-31. PubMed
- Schultze JL, Cardoso AA, Freeman GJ, Seamon MJ, Daley J, Pinkus GS, Gribben JG, Nadler LM. Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity. Proc Natl Acad Sci U S A 1995; 92:8200-4. PubMed
- Matulonis UA, Dosiou C, Lamont C, Freeman GJ, Mauch P, Nadler LM, Griffin JD. Role of B7-1 in mediating an immune response to myeloid leukemia cells. Blood 1995; 85:2507-15. PubMed
- Boussiotis VA, Freeman GJ, Griffin JD, Gray GS, Gribben JG, Nadler LM. CD2 is involved in maintenance and reversal of human alloantigen-specific clonal anergy. J Exp Med 1994; 180:1665-73. PubMed
- Munro JM, Freedman AS, Aster JC, Gribben JG, Lee NC, Rhynhart KK, Banchereau J, Nadler LM. In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease. Blood 1994; 83:793-8. PubMed
- Boussiotis VA, Freeman GJ, Gribben JG, Daley J, Gray G, Nadler LM. Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation. Proc Natl Acad Sci U S A 1993; 90:11059-63. PubMed
- Freeman GJ, Gribben JG, Boussiotis VA, Ng JW, Restivo VA, Lombard LA, Gray GS, Nadler LM. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 1993; 262:909-11. PubMed
- Boussiotis VA, Freeman GJ, Gray G, Gribben J, Nadler LM. B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J Exp Med 1993; 178:1753-63. PubMed
- Gimmi CD, Freeman GJ, Gribben JG, Gray G, Nadler LM. Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci U S A 1993; 90:6586-90. PubMed
- Galvin F, Freeman GJ, Razi-Wolf Z, Hall W, Benacerraf B, Nadler L, Reiser H. Murine B7 antigen provides a sufficient costimulatory signal for antigen-specific and MHC-restricted T cell activation. J Immunol 1992; 149:3802-8. PubMed
- Freedman AS, Freeman GJ, Rhynhart K, Nadler LM. Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway. Cell Immunol 1991; 137:429-37. PubMed
- Freeman GJ, Gray GS, Gimmi CD, Lombard DB, Zhou LJ, White M, Fingeroth JD, Gribben JG, Nadler LM. Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. J Exp Med 1991; 174:625-31. PubMed
- Gimmi CD, Freeman GJ, Gribben JG, Sugita K, Freedman AS, Morimoto C, Nadler LM. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc Natl Acad Sci U S A 1991; 88:6575-9. PubMed
- Freeman GJ, Freedman AS, Segil JM, Lee G, Whitman JF, Nadler LM. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J Immunol 1989; 143:2714-22. PubMed
- Freedman AS, Freeman G, Horowitz JC, Daley J, Nadler LM. B7, a B-cell-restricted antigen that identifies preactivated B cells. J Immunol 1987; 139:3260-7. PubMed
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Diabetes Health Center
Diabetic Diet: 6 Foods That May Help Control Blood Sugar
Broccoli, Spinach, and Green Beans
Add plenty of nonstarchy vegetables, such as broccoli, spinach, and green beans, to your diabetic diet, diabetes experts say. These foods are high in fiber and low in carbohydrates, which make them ideal for people with diabetes.
In contrast, starchy vegetables include peas, potatoes, corn, winter squash, and lima beans. There's no need to cut them from the diet, Moore says. "They do give us additional nutrients. We want to maintain balance." But because starchy vegetables have more carbohydrates and raise blood sugar more, it's important to stick to proper portion sizes, she says.
There's new evidence, too, that vegetables are healthy for people with diabetes.
Researchers have found that a low-fat vegan diet may help type 2 diabetes patients to better manage their disease. In a study published in DiabetesCare, 43% of people with type 2 diabetes who followed a low-fat vegan diet for 22 weeks reduced the need to take diabetes medications. That's compared to only 26% who adhered to the diet recommended by the American Diabetes Association.
On average, the vegan group also lost more weight and lowered levels of bad cholesterol. Because people with diabetes are more prone to heart disease, eating with heart health in mind matters as much as blood sugar control, Moore says.
Some diabetes patients shy away from strawberries because of their sweetness, says Moore. But a cup of strawberries makes for a healthy snack that won't raise blood sugar too much. They're a much better option than a cookie or candy bar.
"They're pretty low in calories and carbohydrates," she says. What's more, strawberries are high in fiber and water, so people will feel fuller longer. The longer that people with diabetes can stay full, the fewer carbohydrates they'll consume overall, she says.
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subset: commoncrawl


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Listen to free music played by zappaconcrete
Blip.fm is internet radio made social. It's easy to search for, play, and discover free music recommended by real people. Join today to create your own free station and start listening to @zappaconcrete.
zappaconcrete this will probably set me on a path you may not want to follow
zappaconcrete right there ....
The Album Leaf – Writings On The Wall| play
zappaconcrete mellow might be an understatement...(sarcasm face)
The Album Leaf – September Song| play
zappaconcrete so I blipped the last 5 from Ireland's Short List best of 2009, so you can see who did not make it....WHAT THE F?
zappaconcrete Short list...
zappaconcrete 2009 Short list nominee
zappaconcrete on the Ireland Short list 2009


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Cousin duo the French Kings celebrates the release of its sophomore effort, Callas. Though its members cite opera and classical music as influences, we hear Ratatat-style computerized emotion and synthetic laments—no surprise, then, to learn that one half of the group was Ratatat's touring keyboardist.
The French Kings + New Beings + Dressage
|Event website:


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|Oh noo, the fangirls are here!
|Oh noo, the fangirls are here!
|I've got plushie/figurine photos, my sister's drawings and more!! Please enjoy my gallery!!^o^
|I approve a lot of things..:'D
Imaginative School, chores, sleep. School, chores, sleep. It gets old after awhile, but what can I do about it? Mother comes home precisely at 11:15. By then, dinner must be done, dishes washed, homework finished, and living room exactly how I left it. The TV seemed repeat perfectly too. The old Teen Titans episodes when I got home at 3:00, the same Fruits Basket episode that has been playing for the past three years at 4:30, and the Harry Potter marathon until 1:00. It's kinda ironic. While most kids struggle with bullies or stress, I almost crave for that kind of excitement just to make it interesting.
The Lake Vic High School was nothing like the schools you see on TV. The teachers were all well mannered and the hallways were almost dead silent in between classes. Most people (including me) had just above average grades while the others were either flunking or drop-outs.
Character Story Test The small town of St. Ives was a rather peaceful town with approximately 150 residents. At least, that's what I've heard about it. As a child, I had never been given the place a gander. The remaining memories I have mostly consist of silhouettes. A woman's soft hand brushing back my untamable curls and a tall man's shadow above my crib. Though my memories may be hazy, my last day in St. Ivs is one I remember clearly.
"Blast! Those barmy pirates are at it again!"
"Belt up, Oliver! You're bein' a wobblin' fool!"
The yelling, begging, and grinding metal all mixed into a harmonizing chaos. Yet the most dreadful part was the silence that had came after.
"You're arse over elbow! There's no way we can escape!"
There were other children down the street screaming; running away to n
|Please donate so I can continue my preium membership. Anyone who does will be featured automatically in these as my token of appreciation. Thanks everyone!^w^


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Yorkshire MESMAC
Yorkshire MESMAC is part of a group of services. Each of these services has a microsite of its own which can be visited by clicking the links above, or please use the links to the left to navigate around the main website.
If you have any news or upcoming events that you would like to display here, please email us with a short paragraph and we will give it due consideration. We also reserve the right to edit any material submitted.
If you would like to book an appointment for an HIV test in your area, please contact us
To find out where and when our next free, rapid HIV testing drop-in sessions are (no appointments needed), please click here
Yorkshire Bears bare all for 2016 Charity Calendar!
Another year, another calendar, but as usual, the Yorkshire Bears are taking the art of calendar making and doing it in style!
Their fabulous 2016 Charity calendar is here and looking swish! But don't take our word for it, why don't you have a closer look and pick one up?Read more...
Click and Collect HIV testing in Leeds
Getting a HIV test in Leeds has never been easier. You can now order your testing kit and collect it from Yorkshire MESMAC Leeds offices at a time that best suits you. If you have recently had condom-less anal sex it's a good idea to get a HIV test – treatments for HIV have never been better and the sooner you know your status the sooner you can take control of your health. To do the test you will need to prick your finger and provide a small sample of your blood in a bottle, you then put this in the post and you will get your results within five working days. You will be notified of your results via text message.
This test is able to tell you whether or not you had HIV in your blood four weeks ago.
If you have any more questions you can call us on 01132 444 209.
To order you test please click on the link below:
PrEP info for people in the UK
Pre-exposure prophylaxis is a course of HIV drugs taken before sex to reduce the risk of getting HIV. It is taken as a tablet once a day and research suggests that if it is taken every day as directed, it is very effective in preventing HIV transmission. PrEP is intended for people who are at high risk of getting HIV. This includes people with a partner who is HIV positive or those who have multiple sexual partners and find it hard to use condoms. This is different to post-exposure prophylaxis (PEP), which is taken after a potential exposure to HIV.
In the UK, PrEP is only available to people who have enrolled in a research trial. This means that PrEP isn't currently available through the NHS on prescription. There is no agreement yet for when this might happen.Read more...
Making It Work: Testing Times in Wakefield
In England in 2013, 59 per 1,000 MSM aged between 15-59 years old were estimated to have HIV. 16% of MSM were undiagnosed.
In 2013, 56 per 1,000 Africans aged between 15-59 year old were estimated to have HIV. 38% of African men and 31% of African women were undiagnosed.
31% of MSM and 58% of African people were diagnosed late in 2013, this is vitally important, you are more likely to die within a year if you are diagnosed late and it reduces your treatment options. 530 people with HIV infection died in 2013, most of whom were diagnosed late.
This is preventable and unacceptable.Read more...
Click and Collect: Postal HIV testing in Wakefield
As part of Yorkshire MESMAC Wakefield's pioneering HIV testing services, we are proud to announce our Click & Collect service for our postal HIV & Syphilis testing service.
For people who want privacy, convenience or to pick up a test in your coffee break, our new premises in Wakefield City Centre is able to offer a Click & Collect service for people who are 16 years old upwards from and are either Men who have Sex with Men and/or African communities.
Click here or on the picture to the right, enter your address as 12 Cheapside, Wakefield, WF1 2SD and collect your free postal HIV & Syphilis testing kit to do at a place of your choosing. Please allow three working days for the kit to arrive in our Wakefield premises.
Text Tom on 07551 159 564 if you would like confirmation that the kit is ready for you and the time you want to collect the kit.Read more...
Exciting changes to Sexual Health Services in Leeds are on their way!
On Wednesday 1 July 2015 Leeds Sexual Health launched. This is a new 'integrated' Sexual Health Service designed to offer people contraception, HIV testing and Sexually Transmitted Infection (STI) testing and treatment.
In October 2015, a new city centre clinic will open within the Merrion Centre but until this time the service will be run from the current bases at the Centre for Sexual Health / Genito-Urinary Medicine (GUM) at the Sunnybank Wing of the Leeds General Infirmary (LGI) and Citywise on Eastgate.Read more...
Passionate about Refugee Women Support?
City of Sanctuary Wakefield are seeking enthusiastic volunteers to join their dynamic Women's group that provide weekly support sessions and activities for women and children in Urban House. City of Sanctuary is a movement to build a culture of hospitality for people seeking sanctuary in the UK.
Urban House is an initial accommodation centre for asylum seekers, many of whom have just arrived in the UK after fleeing violence or persecution. Our residents are from all over the world, from all walks of life, and speak a vast array of languages.
Volunteering is an opportunity for you to offer valuable support to women at a difficult and uncertain time in their life. Role Description• Supporting women by listening• Helping to create a relaxing atmosphere• Getting involved in craft activities • Helping with setting up the sessions and clearing away• Participating in volunteer meetings at Urban House and within the City of Sanctuary group• Attending training sessions, as appropriate
They ask that you commit to volunteering for 3 hours a week (Monday 1.30-4.30pm), for at least 6 months.
Welcome to Wakefield MESMAC
Yorkshire MESMAC Wakefield is proud to announce that we have won the Wakefield contract for continuing to offer our award winning HIV Support and Prevention services for Wakefield District. We are also now open for business at 12 Cheapside, Wakefield, WF1 2SD. Landline phones, printer and full internet service not quite there yet. Everything else is!
We've listened to our service user feedback and found a lovely place near Wakefield bus station, Wakefield Westgate rail station AND Josephine Butler Centre for Sexual Health Wakefield to make it even easier to access our services.
And that's not all...Read more...
Domestic Abuse in LGB&T* Relationships Workshop Wakefield
Domestic abuse can take many forms, with different actions being used against someone in order to gain power and control. Abusive behaviour may include physical violence, emotional and psychological manipulation, financial control, sexual assault and unwanted sexual behaviours. These behaviours can be used to control a person or make him or her compliant and fearful. Domestic abuse also includes being forced to marry someone you don't choose, and being made to do things by your family to protect family 'honour'.
Do you know anyone who has been a victim of domestic abuse? To what extent does domestic abuse play a part in LGB&T* relationships? What support needs to be in place to prevent domestic abuse? What services are currently available in Wakefield District? And what does a 'healthy' relationship look like?Read more...
Welcome to Hull
Did you know that 2015 year marked the exciting start of Yorkshire MESMAC services in Hull.
Please click here to go to the Yorkshire MESMAC Hull page for further details.
Keep tuned for details on the launch of venues for Testing Times and volunteering opportunities.


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* * * * * *
Congratulation to the winners
Best of Show
Shades of Purple by Brianne Moores
1st Place
Dog Park by Karen Clatanoff
quilted by Brianne Moores (Sequim Quilt Company)
2nd Place
William Morris II by Diane Shafer Davis quilted by Sharon Witt
3rd Place
Twilight in the Four Corners by Denise Cheney
4th Place
Dahlia Quilt by Judy Ramos
5th Place
The Butterfly by Mary Ann Clayton
CLUB CHALLENGE (Through the Eyes of a Child)
Viewer's Choice: Hogwarts by Wendy Whittemore
(with the grown up "child" artist)
CONGRATULATIONS also to Sylvia Johnson of Sequim,
winner of our beautiful raffle quilt.
Thanks to all who purchased tickets.
|Copyright © 2015 Sunbonnet Sue Quilt Club. All rights reserved. Website by Websites For Quilters.


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A Few Acres of Snow' is a two player game about the struggle between Britain and France for control of North America, fought during the seventeenth and eighteenth centuries. A war fought at the edge of two mighty empires. For over one hundred and fifty years Britain and France were locked in a struggle for domination of North America. Thousands of miles from their homes, settlers and soldiers were faced with impenetrable forests, unpredictable American tribes, and formidable distances. Despite these obstacles they were able to engage in bitter warfare, with the British ultimately taking the prize of Quebec. A Few Acres of Snow is a two-player game that allows you to recreate this contest. You can change the course of history by your decisions. A Few Acres of Snow takes an innovative approach to the subject, using cards to represent locations and manpower. As the game progresses you add to your selection of cards, increasing the range of actions available to you. There are many strategies to be explored. How quickly should you build up your forces, do you employ Native Americans, what energy should be expended on your economy? For 2 players. Ages 14 and up. Playing Time: 60 to 90 minutes. Deck building and territory control mechanics.
Manufacturer's Suggested Age: 14 Years and Up
Includes: Instructions, Cards, Game Pieces
Material: Cardstock, Plastic
Playing Time: 1-2 Hours
Number of Players: 2 Players
Level of Difficulty: Intermediate
Battery: no battery used
other Info.
- Online Item #: 15689929
- Store Item Number (DPCI): 087-10-1434
- Imported


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Huge 5BR house in the orange groves, slps 10 - BS646
From $154 / night
Description from the manager
Description from the manager
Bedrooms: 5/
Bathrooms: 3/
Sleeps: 12/
Type: House
Set within the prestigious Highlands Reserve Golf & Country Club which is situated on US Highway 27 in a peaceful location. The community is set amongst beautiful rolling countryside and an abundance of pine trees and orange groves adding to the natural beauty of the area. Walt Disney World is just 10-15 minutes away on Highway 192 and Interstate 4 is only 5 minutes away which will connect you to all that Orlando has to offer as well as the beaches of the Gulf Coast. The championship Mike Dasher designed golf course offers you pine tree lined spacious fairways likened to the great Scottish courses. The open course will be both challenging and ...Read more
About the manager
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Contempo Florida Holidays
Contempo Florida Holidays
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Product Details
Ford Ranger 1993-1997, Super EDIS Ignition Coil Pack by Accel®. Accel offers the only true high-performance Ford 4-tower style EDIS coil. Advanced bobbin technology, specialized magnetic steel core and optimum windings result in higher energy and voltage outputs plus arc duration. Direct bolt/plug in install.
- The finest quality at a great price
- Improves your engine's performance
- Built from the sturdiest materials
- Includes everything needed for easy installation
These Accel ignition coils are engineered to be the only true performance Ford 4-tower style EDIS coil. Advanced bobbin technology, highly specialized silicone magnetic steel core, optimized winding, resistance, and turns ratio result in higher energy and voltage outputs, and longer arc duration. Direct OEM replacement. Must use factory firing order.Engineered to be the only true performance Ford 4-tower style EDIS coil. Special high temperature epoxy resists shock and vibration, while increasing thermal conductivity. Secondary towers molded in high dielectric strength ACCEL Yellow. Packaged as single unit; 4 cyls require 1 coil pack, "twin plug" 4 cyls require 2 coil packs and 8 cyls require 2 coil packs. No tsuitable for some late 1999 applications.77.77 90.96
Being the leader in performance ignition systems and components, Accel offers a huge variety of fuel injectors, distributors, coils, ignition wires, spark plugs, and other products that are designed and engineered to breathe new life into your vehicle's ignition system. The company is dedicated to research, engineering and testing results in products that enable the performance enthusiast to reach peak performance through the management of fuel mixture, ignition timing, and spark delivery. Accel's goal has always been to lead the market with innovative new products designed to push the power, speed, and performance of street and strip machines as quickly as automotive technology advances.Product Reviews (1)
Every Customer can leave a review about our service and the product that was purchased. In order to leave your review for your new product, please follow the link in the email you receive after completing your purchase. You can rate appearance, ease of installation, price/value and product quality.Accel® - Super EDIS Ignition Coil PackAverage Rating: 5 of 5APPEARANCEEASE OF INSTALLATIONPRICE/VALUEQUALITYAll Accel Reviews(5)APPEARANCEEASE OF INSTALLATIONPRICE/VALUEQUALITY2005 Ford Mustang | Posted by Cameron | (Smithfield, NC)
It works very well and can tell a great difference from the stop one.Was this review helpful for you? YesNoShare this review:
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You will never pay more with CARiD! Not only will we match prices from any competitor's website or other reputable source, we will continue to honor that promise for up to one year after your purchase.
We'll match the price at time of purchase, or refund you the difference if done after the purchase. Either way, we are totally committed to providing you the best online shopping experience.
We're car and truck enthusiasts, just like you! And it's enthusiasts we hire in our Sales and Service Centers. Many of our staff are ASE certified and have spent years in the retail auto business.
We conduct our own in-house training, and we even bring vendors to us for hands-on product training demonstrations. You're getting true expertise when you phone or email us!
With hundreds of vendors, and tens of thousands of components for sale, we put tremendous effort into coordinating our data with our vendors' data in order to guarantee that you get the correct part.
Our huge database is regularly cross-checked to keep it current and optimized. At times, our thoroughness makes our data even more accurate than our suppliers! This rigorous process means that you can always order with confidence.


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This Employer's Jobs
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Advice on Interviewing
for Faculty Jobs
A series of experts offer tips for what to do -- and not to do -- when you meet with search committees and department chairs.
Waubonsee is not your average community college — and that's how we like it.
We take pride in exceeding expectations, offering a top education to all students willing to work hard for their dreams. Waubonsee has top-ranked academic programs, a dynamic student population, a breadth of services and resources, and a growing campus network — all of which mean a richer college experience for you.
Mission Statement
Waubonsee Community College is a public, comprehensive community college that was organized in 1966, as mandated by the Illinois Community College Act, to provide education and training services for individuals in portions of Kane, Kendall, DeKalb, LaSalle and Will counties of District 516. The philosophy of Waubonsee Community College is based on the premise that education is the cornerstone of a literate, democratic society; that learning is a lifelong process; and that the pursuit of knowledge must be supported by institutional policies that demonstrate the values of accessibility, service, value, quality and innovation.
Waubonsee Community College opens the door of knowledge, sparks imaginations, and enlightens lives through learning. We welcome the diverse abilities, goals, and experiences of individuals standing on the threshold of discovery. Our success is defined by the dreams we help shape, the opportunities we help design, and the futures we help create.


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- Northern New York Newspapers
- Watertown
- Ogdensburg
- Massena-Potsdam
- Lowville
- Carthage
- Malone
- NNY Business
- NNY Living
- NNY Ads
The flap over windows on Stephen J. Bradleys Court Street building has been resolved.
Mr. Bradley said Friday that he and Neighbors of Watertown officials have worked out an agreement that will allow him to restart work on his project to convert the upper floors of his building at 150 Court St. into apartments.
As he had planned, Mr. Bradley, whose business, Abbey Carpet, occupies a storefront in the building, can use the smaller third-floor windows as part of the project. But, Mr. Bradley said, he must install transoms above those windows.
Transoms are small windows that are placed above solid beams to separate the top of a window or door from the wall.
Mr. Bradley, a former Watertown City Council member, declined to discuss the compromise except to say he is satisfied because the project is moving forward. When asked how much the transoms were costing him, he said only, enough. Work can proceed as soon as the transoms are delivered in about three weeks.
In October, the issue over the windows had become such a controversy that representatives from the Watertown Local Development Corp. and Watertown Savings Bank met with Mr. Bradley and Neighbors Executive Director Gary C. Beasley to see if something could be worked out to resolve the issue.
Mr. Beasley, who was out of the office Friday and Monday and could not be reached for comment, had expressed concern then that the windows were not historically correct and did not match windows in adjacent buildings. He also contended the smaller third-floor windows did not comply with strict guidelines under the New York Main Street facade program that Neighbors was overseeing.
As a result, Mr. Beasley issued a stop-work order.
In October, Mr. Bradley said he had to use the smaller windows because of the juxtaposition of the ceiling on that floor, and he had to follow state fire codes. He also said he has tried to maintain other historical characteristics of the building during the project.
Thousands of readers like you have made Northern New York Newspapers the number one ranked website* for local news and sports coverage in the north country.
You can continue on to this article in a few seconds, or you can visit one of our websites:


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*** there is a lot of info here. Main event info directly below. For weekend-long side events, see bottom of page -Nic
Official hashtag: #gpdc
Date: June 27-29, 2014 Format: Limited - Theros Block
Tournament Location
Dulles Expo & Conference Center North Hall
4368 Chantilly Shopping Center
Chantilly, VA 20151
Click here for map.
Entry into the Grand Prix event venue is free of charge.
Registration: $50.00
Online registration available at www.TJcollect.com until Thursday, June 26 at 11:30 p.m. Onsite registration available on Friday, June 27 from 2:00 p.m. to 9:00 p.m.
There will be no Saturday registration for this event.
Get your promo card by playing in the Grand Prix (while supplies last).
Truly a Magic-al weekend, the fun begins on Friday! FREE MINI MASTER from 12:00 p.m. to 12:30 p.m. In addition, there will be non-tournament events starting on Friday with our new Magic Panels, Magic Trivia, Pro Player meet-and-greet, Magic Deck Doctor, and more. The side event schedule is full with an event for everyone serious and casual alike. Wacky Drafts, Standard Showcase, Modern Mayhem, Cobra Commander, Team mini master and Innistrad Sealed Deck provide the opportunity for memorable Magic experiences that lead to a fun filled weekend.
Of course there is the main tournament—GP DC will be one of the only complete Theros Block Grand Prix events in the world! The weekend concludes with one of the hottest events in Magicdom - the Super Sunday Series. Grab a spot at the most exclusive, high-stakes Magic event around—and an all-expenses paid trip to Seattle and Wizards of the Coast to play for a prize pool of $20,000 (under 50 players will be invited!)
DailyMTG.com and Twitch.tv. The live video stream will start at approximately 2 p.m. local time / 6 p.m. GMT Saturday.
Participate in select events at Grand Prix Washington DC and receive an exclusive playmat featuring the promo art for Magister of Worth by rk post! For details, see www.tjcollect.com!
Theros/Born of the Gods/Journey into Nyx Sealed Deck/Draft
Participation Fee: $50
Registration and Schedule Online Registration until June 26 at www.tjcollect.com Friday, June 27: Registration: 2:00 – 9:00 p.m. Saturday, June 28: Grand Prix Washington DC begins at 9:00 a.m. Sunday, June 29: Day Two begins at 9:00 a.m.
Registration to the Grand Prix main event closes Friday night. There will be no Saturday registration.
The main tournament at Grand Prix Washington D.C. is open to Magic players of all ages.
Players must have a signed waiver and consent form to compete at Grand Prix Washington D.C.. Forms can be downloaded here and will be available onsite. Minors must have a parent or guardian's signature on these forms. Minors will not be able to register or play unless we receive a waiver signed by a parent or guardian. No exceptions.
Tournament Format
Theros/Born of the Gods/Journey into Nyx Sealed Deck/Draft Day One: Sealed Deck Day Two and Top 8: Booster draft Sealed Deck Product: 2 Journey Into Nyx boosters, 2 Born of the Gods boosters, 2 Theros boosters Booster Draft Product: 1 Journey into Nyx booster, 1 Born of the Gods booster, and 1 Theros booster (drafted in that order) Deck lists are required.If product is not stamped or preregistered, deck registration and deck swap will be performed for the Swiss Sealed Deck.
Tournament Structure Modified Swiss-style (50-minute rounds).Day One will consist of a maximum of 9 Swiss rounds. Day Two will consist of 6 Swiss rounds and the Top 8 single-elimination finals.If 799 or less players register for the event, all players with an X-2-0 record (or better) or the top 64 players – whichever is greater – advance to the second day of competition for prizes and invitations.If 800 or more players register for the event, all players with an X-2-0 record (or better) or the top 128 players – whichever is greater – advance to the second day of competition for prizes and invitations.The Top 8 players after the final Swiss round on Day Two will advance to the Top 8 single-elimination playoff.Top 8 playoff matches will be best 2 of 3.Top 8 playoff matches will have no time limit. (Players are still expected to play at a normal pace and complete playoff matches in a reasonable amount of time.)The Top 8 players will be seated randomly at the draft table immediately prior to drafting.
The head judges for Grand Prix DC are Kevin Desprez (Level 5) and Jared Sylva (Level 4). Judges interested in applying should do so through the Judge Center. Additional questions may be addressed to [masked].
Planeswalker Points multiplier 8x, Rules Enforcement Level (REL) is Competitive on Day One and Professional on Day Two. The Magic: The Gathering Tournament Rules and the Magic: The Gathering Infraction Procedure Guide are in effect for this event unless specifically overruled by information in this Format Document. Rules documents can be found in the Magic Document Center .
Third-Round Byes
Players who have accumulated at least 1,500 Planeswalker Points in the 2014 Seasonal Award Season #2 (March 10, 2014 – June 1, 2014)Players who have accumulated at least 1,500 Planeswalker Points in the 2014 Seasonal Award Season #3 (June 2, 2014 – August 24, 2014) Players with a Pro Tour Players Club level of Gold or Platinum Members of the Pro Tour Hall of Fame
Second-Round Byes
Winners of Grand Prix Washington D.C. Trial tournaments. Players who have accumulated at least 750 Planeswalker Points in the 2014 Seasonal Award Season #2 (March 10, 2014 – June 1, 2014)Players who have accumulated at least 750 Planeswalker Points in the 2014 Seasonal Award Season #3 (June 2, 2014 – August 24, 2014) Players with a Pro Tour Players Club level of Silver
First-Round Byes
Players who have accumulated at least 400 Planeswalker Points in the 2014 Seasonal Award Season #2 (March 10, 2014 – June 1, 2014)Players who have accumulated at least 400 Planeswalker Points in the 2014 Seasonal Award Season #3 (June 2, 2014 – August 24, 2014)
Trial winners
Winners of a Trial tournament are awarded two byes in the Grand Prix that it feeds. Trial byes are not cumulative with other byes and do not pass down. Byes are not cumulative throughout the season or year. Byes do not pass down under any circumstances. Players who accumulate multiple byes to a particular Grand Prix tournament receive only the bye for the greatest number of rounds. For complete information about Grand Prix byes and their corresponding competitive season, please check the Magic Premier Event Invitation Policy.
www.TJCollect.com website. All side events (except casual events) will have a Planeswalker Points multiplier of 3x.
Last-Chance Trials
Earn a valuable Two-Round bye by winning one of the Last-Chance Trials. Last-Chance Trials are 32-person single-elimination events, starting as soon as 32 players register. For more info, check out the Byes section of this page.
"Foiled Again"
A straight Swiss tournament lasting three or four rounds. Participants get 1 past promo card for playing, then one additional promo card per match win. Format varies by event.
Value Drafts
Enjoy a special discount on pick-up drafts on Saturday. Actual times and prices vary by event.
"Rebound" Event
Format at organizer's discretion. The winner(s) earn free entry into the "Super Sunday Series" (see below). Players who also played in the main Grand Prix tournament will get a discount for entry.
Super Sunday Series
Qualifier tournaments for the Super Sunday Series will be held at each Grand Prix. The Top 8 players in the Super Sunday Series qualifier will each be awarded a commemorative Grand Prix water bottle. The winner of the Super Sunday Series qualifier will earn an invitation and travel award for the Super Sunday Series Championship 2015, expected to be held in January[masked] in Seattle. The Super Sunday Series Championship experience also includes a tour of Wizards of the Coast, dinner with Wizards employees, and more.
Weekend-long Events!
"Go Infinite" Booster Draft
Theros Format: Booster Draft
Entry Fee: $15.00
Structure: 8 players, Single Elimination
Prizes: 1st: 6 Theros boosters & free entry into another booster draft at GP DC (or 3 boosters) 2nd: 4 Theros boosters 3rd-4th: 1 Theros booster
8-Player Constructed Win-a-Box
Format: Standard, Modern, Extended, Legacy
Entry Fee: $15.00
Structure: 8 player, Single Elimination
Prizes: 1st: 1 box of Theros boosters2nd: Free entry into another 8-Player Constructed Win-A-Box Event (or 3 boosters)
4-player Commander/EDH
Format: Commander
Entry Fee: $10
Prizes: 4 Theros boosters per opponent eliminated
4 Team (8 player) 2-Headed Giant Booster Draft
Format: Draft from 6 boosters
Entry Fee: $34/team
Structure: Single Elimination
Prizes: 1st Place team: 6 Theros boosters per player2nd Place Team: 4 Theros boosters per player
FOR MORE INFO ON EVENTS, GO HERE: www.TJCollect.com
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— Rafaël, started French Conversation Group
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The November CTP for SQL Server 2008 introduced our new Lookup Transform. 2005 packages with lookup components will upgrade automatically when opened/run in 2008, and should function the same as they did in 2005 with one minor caveat.
In certain scenarios, dataflows containing lookups with matching SQL queries would implicitly share a cache. As this implicit sharing was somewhat error prone, it has been removed in 2008. To share a lookup cache, you can now use the new cache connection manager.
For more info about the 2008 lookup changes, you can take a look at Jamie Thomson's write up.
PingBack from http://geeklectures.info/2008/01/08/no-more-implicit-lookup-cache-sharing-in-katmai/
Improved Scripting SQL Server 2008 (Katmai) introduces VSTA as our new scripting engine, which replaces


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By Mary Coffman
The Tri-Cities Area Journal of Business is seeking the area's rising young stars of business to highlight in its Mid-Columbia Young Professionals awards. This is annual contest's eighth year, and we've recognized some of the most outstanding young leaders, entrepreneurs and business owners in the community.
Nominees don't have to be business owners. They can be professionals in any field, from doctors or lawyers, to chefs, winemakers or dental assistants. They need to have distinguished themselves within their career, company or industry and within the community. We're looking for those young people who not only excel in their jobs, but also are passionate about their community and find ways to get involved and give back.
Last year's winners were: Byron Martin, owner of Teknologize; Justin Christensen, R.E. Powell Distributing; Leo Martinez, Numerica Credit Union; Megan Savely, Frost Me Sweet; Preston House, Papa John's; P. Simon Mahler, S.C.O.R.E.; Ryan Brovont, Columbia Valley Family Farms Inc.; and Travis Adamson, Blodgett, Mickelsen and Naef, P.S.
The nominations deadline is Aug. 31 and nominations will only be accepted electronically.
Nomination applications are available for download at www.tricitiesbusinessnews.com and complete applications must be emailed to firstname.lastname@example.com. Handwritten or printed applications will not be accepted.


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Kenny Chesney Sells Out Both Big Revival Tour Kickoff Shows
Kenny Chesney is kicking off his Big Revival Tour with two huge Nashville shows. Fans in Music City were so eager to grab tickets to the event, that both shows have officially sold out.
Kenny Chesney is kicking off his Big Revival Tour with two huge Nashville shows. Fans in Music City were so eager to grab tickets to the event, that both shows have officially sold out.
Kenny Chesney is kicking off his new tour in Nashville -- twice! Thanks to a high demand for tickets, Chesney has added another night to open the 2015 tour in his hometown.
'Wild Child' is one of the signature songs on Kenny Chesney's 'The Big Revival' album, and not just because it reunites the singer with Grace Potter.
Kenny Chesney will make his long-awaited return to the stage in the home of country music. The superstar will kick off his upcoming the Big Revival Tour with a gig at Nashville's Bridgestone Arena on March 26.
We all know some of country's top stars earn big bucks, but a new article breaks it down in a startling way.
Kenny Chesney is one of country music's biggest stars, but do you know where he got his start in Nashville? It's about as unglamorous of a gig as you can imagine, and what's worse is he didn't last a week! Learn all about it, plus why he was supposed to be at Ground Zero on 9/11 during this week's episode of 'You Think You Know Country?'
Kenny Chesney was given the first-ever Groundbreaker Award at the American Country Countdown Awards in Nashville on Monday night (Dec. 15).
With the holiday season here once again, WKDQ has begun to play the Christmas tunes you know and love. From traditional tunes like "O Holy Night,' perfected by artists like John Berry, to more recent classics, like 'All I Want For Christmas Is You' by Vince Vance and The Valliants, there are some songs you hope to hear every year, but then again new songs or versions of songs that are added to the fold...
Kenny Chesney has brought Christmas back to the islands. 'Christmas in Blue Chair Bay' is his first holiday recording in over a decade, and it captures the same sense of chill his 2003 album did.
In a new interview, Kenny Chesney takes issue with country songs that "objectify" women, and now fellow country star Clay Walker has responded to those comments.
Kenny Chesney is trying to buck one of the biggest trends that's currently succeeding at country radio.
As if Kenny Chesney's Big Revival Tour could get any bigger, Eric Church has announced he'll be joining the superstar for five stadium shows!


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WooTravelling Atocha 107 HOMTELS, Madrid
- Free WiFi
- Airport within 5 mi/8 km: Madrid (XOC-Atocha Train Station)
Main amenities
- 20 smoke-free apartments
- Self parking
- Airport shuttle
- Air conditioning
- Garden
- Self-serve laundry
- Multilingual staff
- Luggage storage
- Limited hour front desk
- Tour/ticket assistance
What's around
- In Retiro
- Prado Museum (0.5 mi / 0.9 km)
- Reina Sofia Museum (0.3 mi / 0.4 km)
- Thyssen-Bornemisza Museum (0.4 mi / 0.6 km)
- Plaza Mayor (0.8 mi / 1.2 km)
Well located apartment with renfre station and metro only a few minutes walk. Very noisy…
In happening part of Madrid walk to museums parks station cafés bars and interesting…
Enter dates to check prices
Hotel Info: 1800-687-236 (Australia Toll Free)from A$177
- Standard Studio, 1 Double Bed
- Deluxe Studio, 1 Double Bed
- Standard Apartment, 1 Bedroom (3 people)
- Standard Apartment, 2 Bedrooms, 2 Bathrooms
- Standard Apartment, 2 Bedrooms
Recommended hotels
At a glance
Key facts
Hotel size
- This hotel has 20 rooms
- Check-in time 3 PM-midnight
- Check-out time is 11:30 AM
- Express check-in/out
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Up to 2 children (12 years old and younger) stay free when occupying the parent or guardian's room, using existing bedding
- No pets or service animals allowed
- Free WiFi in public areas
- Free WiFi in rooms
- Airport shuttle (available on request) *
- Self parking *
- Accessible parking
Other information
- Smoke-free property
Nearby Four Star Madrid hotels
In the hotel
- Front desk (limited hours)
- Tours/ticket assistance
- Laundry facilities
- Luggage storage
- Elevator/lift
- Garden
- Disabled parking
In the room
- Air conditioning
- Coffee/tea maker
- Iron/ironing board (on request)
- Down comforter
- Sofa bed
- Sofa bed size double
- Memory foam mattress
- Individually decorated
- Individually furnished
- Separate living room
- Private bathroom
- Bathtub or shower
- Hair dryer
- Desk
- Free WiFi
- Refrigerator
- Microwave
- Kitchen
- Cookware, dishware, and utensils
Top Madrid hotels
Recently reviewed hotels in Madrid
- Zenit AbebaFrom
- Hotel Gran LegazpiFrom
"Loved the location, near La Rambla, great choice of restaurants close by, best breakfast buffet I had in all of Spain. Rooms are not sound proofed so can hear other residents…"Sep 2, 2015
- One Shot Recoletos 04From
"Excellent location for getting to all the must see locations around Madrid. Two metro stops are very close to the property and Atocha Rail Station is also only a €5-8 cab ride…"Aug 30, 2015
- Vincci Vía 66From
Nearby hotels
WooTravelling Atocha 107 HOMTELS, Madrid's small print
Also known as
- Atocha 107 HOMTELS
- WooTravelling Atocha 107 HOMTELS
- WooTravelling Atocha 107 HOMTELS Apartment
- WooTravelling Atocha 107 HOMTELS Apartment Madrid
- WooTravelling Atocha 107 HOMTELS Madrid
Cash transactions at this property cannot exceed EUR 2500, due to national regulations. For further details, please contact the property using information in the booking confirmation.
Parking height restrictions apply.
For transfers, guests must contact the property 72 hours prior to arrival at the number on the booking confirmation.
Optional extras
Late check-out can be arranged for an extra charge of EUR 15
Self parking costs EUR 20 per day
Housekeeping is offered for an extra charge of EUR 30 per day
Rollaway beds are available for EUR 15 per night
Airport shuttle service is offered for an extra charge of EUR 35 per vehicle (one way)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


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Download Software Download Manual
VRide software allows you to ride with unlimited numbers of other riders in real time with the worlds highest quality Full HD cinema quality video simulation collection on some of the world's best known and most scenic courses…
Demo Video 1 Demo Video 2 Demo Video 3
VRide uses map view and personalized icons to show your position and speed in real time, along with the position and speed of any other users on the same course. Ride with the pack or blow past riding buddies with a unsurpassed real life look and feel.
VRide works with LYNX, Computrainer, KICKR, Tacx Smart and many other ANT+™ resistance trainers. Visit our store page to register and sign up. Watch
our short how-to video and follow the simple instructions.
"Unlike Zwift… VRide Multi's focus is hi-def video of actual cycling courses, such as the Stelvio in Italy, the Koppenberg in Belgium or L'Alpe d'Huez in France. All told, there are more than 2,000km of courses to ride."
Ben Delaney – February 11, 2015
- Software is 64 bit and requires 64bit version of Windows 7 or Windows 8.
- Works on MAC under dual boot. MUST BE BOOTCAMP.
- Please download the free software and free demo videos, and verify the VRide software works with your computer and works with your trainer before buying videos.
- Software is lean, unzip it to install. Click v-ride.x64.exe it to run it.
- Just run the executable, enter your settings and enjoy.
- Ride famous cycling roads filmed in HD with cinema grade cameras.
- All videos come with precise road profiles – gradient/altitude vs distance.
- Video distance/playback speed perfectly synchronized with your power output.
- Create and ride structured workouts.
- Export your rides and workouts to TCX format to any 3rd party cycling analytic software or website.
- Supported trainers include any FE-C compliant trainer, LYNX, Wahoo KICKR/SNAP, Computrainer or any resistance trainer equipped with ANT+™ speed/cadence sensor and/or power meter.


text:
Today | This Week
Dressed by Angels
Loading Bay | 0203 773 8995
Private View: Thursday 1st October 10am 3pm / from 6.30pm
Opening Dates: 2nd October 2015 3rd January 2015
This brand new exhibition tells the story behind the worlds greatest costume house, presenting visitors with an irresistible mix of costumes from film, TV, theatre and radio. Angels Costumiers has been dressing the world for 175 years, including many Oscar and BAFTA Award winning films, and Olivier and Tony Award winning theatre. Over seven generations of one family, Angels has become the premiere costumier to the world. This is their story in costumes.
Adults £16.00 / Children (to 16) £9.00 / Concession (seniors, students, disabled passes) £13.50 / Family (4): £45.00 / Family (5) £54.00 Groups: (8+) £12.50 / (School groups) £8.00
Facebook // Twitter
The Old Truman Brewery | 02077706022
Thursday 8th Tuesday 13th October 2015
PHOTOBLOCK brings together all things photographic in a week of engaging events here at The Old Truman Brewery.
PHOTOBLOCK is the new visual initiative from The Old Truman Brewery. Boasting a collection of photographic events set to create a wider experience and engagement for all things photographic here in the East End.
October welcomes a new season and a busy time for creatives in the capital with the annual Frieze Art Fair and the return of East Londons Photography Festival, Photomonth.
If thats not enough to bring you to the East End this fall, weve made sure that PHOTOBLOCK, in its second year, provides an eclectic mix of Photographic events - including The Royal Photographic Societys International Print Exhibition 158 - reflecting both contemporary and traditional forms of practice.
Facebook // Twitter
F Block, G5. | 02077706022
Private viewing: Thursday 8th October 2015 | 6.00pm 9.00pm
Open to the public: Friday 9th Sunday 11th October 2015 |
10am - 6pm
As part of PHOTOBLOCK, The Old Truman Brewery will be bringing you PHOTOMASTERS. Coordinated and produced in house we aim to bring you an inspiring showcase of recent MA Photography Graduates work from across the UK.
The Old Truman Brewery and the producers of Free Range Shows have created the PHOTOMASTERS showcase of MA Photography students and recent MA graduates work, to coincide with PHOTOBLOCK, a week of diverse photographic events at The Old Truman Brewery and East Londons Photomonth.
We are also excited to announce that the Royal Photographic Society will be exhibiting their International Print Exhibition 158, alongside the PHOTOMASTERS exhibition. RPS will be at the forefront of the exhibition showcasing professional photographers and enthusiasts prestigious work.
The Royal Photographic Society @ PHOTOBLOCK
F Block G4
Private view: Thursday 8th October 2015 | 6.00pm 9.00pm
Open to the public: Friday 9th - Tuesday 13th October 2015 | 10am - 6pm
The Royal Photographic Society's International Print Exhibition 158 has been held almost every year since 1854. Now in its 158th year, it is the longest running exhibition of its kind in the world. Embracing all genres and styles of photography, the exhibition of 100 prints combines photographic skill with ideas rich in meaning, message and technique. This unique selection of images, curated by a panel of renowned photographers and photographic professionals, will ultimately offer something that will challenge your ideas and capture your imagination.
AOP Photography Awards 2015 @ PHOTOBLOCK
F Block T1
Fri-Sat 10am-5.30pm | Sun 10am-5pm
(Awards Presentation 8th | 6.30pm-10.30pm)
The AOP Photography Awards continues to be regarded as the most prestigious and highly respected competition for professional photographers worldwide.
Being selected for the Book and Exhibition is one of the greatest accolades available to professional photographers and offers major exposure to art buyers and the creative industry as a whole.
The awards comprise of the Open, Assistant and Photography categories.
There will be a busy programme of seminars and events from 8th-11th
October: see www.the-aop.org/events for further details.
Fotonow SWGPP @ PHOTOBLOCK
Shop 12
Friday 9th Sunday 11th October
Friday & Saturday | 10am - 8pm
Sunday | 10am - 5pm
South West Graduate Photography Prize is an annual initiative developed and managed by Fotonow (CIC). Recent photography graduates can submit work, which is then shortlisted, with final exhibition of six artists appearing at PHOTOBLOCK (London) during October. One artists is selected to undertake a residency with Fotonow and Knowle West Media Centre each year. The initiative is aimed to support young photographic artists who are recently leaving educational institutions within the South West region.
Exhibiting Artists; Caitlin Chescoe, Simeon Meinema, Sarah Remy Mitchelson, Joseph Ball, Jess Leonard and Dominic Till
http:// www.photomonth.org
Shop 7
Open to the public: Thursday 8th - Sunday 11th October
Thursday 8th October | 6pm - 9pm
Friday & Saturday 9th & 10th October | 12pm - 8pm
Sunday 11th October | 12pm - 6pm
Free Admission
A celebration of independent photobooks and local publishing with a BOOK MARKET, Q&As, Talks & Events.
Presented by Photomonth East London with Hoxton Mini Press and Mini Click.
Dray Walk Gallery
Open to the public: Friday 9th October - Tuesday 20th October 2015
Mon-Sat 11am-9pm | Sun 11am-6pm
A unique photography event from the team behind 125
Each year photographers around the world are invited to
upload imagery for inclusion in an exhibition, awards and
book which is curated by the 125 team and key industry
Visitors can immerse themselves in a carefully constructed
snapshot of contemporary photography as well as guest
lectures from leading artists and industry figures plus
weekend workshops for all levels.
All imagery is available to buy as limited edition art prints
with prices ranging from £100 to £5000.
Last year 125LIVE attracted 6000+ visitors and this year
will be even bigger.
Twitter // Instagram //
The Old Truman Brewery | 02077706001
Thursday 15th October Monday 19th October 2015
ARTBLOCK is an alternative selection of Art fairs and exhibitions, taking place at The Old Truman Brewery in October. This years selection features The Immigrants/ Pinta London, The Other Art Fair, Moniker Art Fair, ARTMASTERS and a host of independent shows.
Facebook // Twitter
Ant Carver - Nothings Wrong Somethings Right @ ARTBLOCK
Shop 7 | 07515476133
Open to the public: Thursday 15th - Friday 16th October | 11am - 9.30pm
Saturday 17th - Sunday 18th October | 11am - 8pm
Monday 19th - Tuesday 20th October | 11am - 7pm
Ant Carver will be exhibiting his distinctive series of portraits in a week long exhibition, titled Nothings Wrong Somethings Right. Using spray paint as the basis for his backgrounds, his style brings together graffiti techniques and bold, highly detailed oil paint portraits. His first London solo show will run from Thursday 15th Tuesday 20th October 2015 in Shop 7, Dray Walk, The Old Truman Brewery, London, E1 6QL
Facebook // Instagram
Emily Ball Studios - Nine Artists @ ARTBLOCK
Shop 12
Open to Public: Thursday 15th October Tuesday 20th October 2015 | 11am-7pm |
An exciting and vibrant Group Exhibition of Nine Professional Artists and the Emily Ball Studio of Contemporary Painting in Sussex. Short courses run all year- work with practicing artists who generously share the rich and diverse possibilities of contemporary drawing and painting.
Emily Ball, Edith Pargh Barton, Jane Cattlin, Avis Lane Willan, Carolyn Macleod, Juliet Robertson, Judith Smith, Julie Wall, Fran White. Also showing sculpture by Guy Portelli.
The Old Truman Brewery | 02077706022
Private view: Thursday 15th October 2015 | 6.30pm- 9.30pm
Open to the public: Friday 16th Sunday 18th October 2015 |10am - 6pm
As part of ARTBLOCK, The Old Truman Brewery will be bringing you ARTMASTERS. Coordinated and produced in house we aim to bring you an inspiring showcase of recent MA Fine Art Graduates work from across the UK.
Facebook // Twitter
Moniker Art Fair @ ARTBLOCK
F Block T1
Thursday 15th | 5pm - 9:30pm Private View
Friday 16th | 12pm - 9pm
Saturday 17th | 11am - 7pm
Sunday 18th | 11am - 6pm
Moniker Art Fair returns for its sixth year, on October 1518 at the Old Truman Brewery, having firmly established itself as Londons premiere event for contemporary art with its roots embedded in urban culture.
Building on the foundations of five years experience and its continued success, Moniker Art Fair will be again venue-sharing with Londons leading artist-led fair, The Other Art Fair, in what will be a showcase of independent and established talent all under one roof in East Londons iconic Old Truman Brewery.
Hunt @ ARTBLOCK
F Block T2
Private View: Thursday 15th October 2015 | 5pm - 9:30pm
Open to the public:
Friday 16th October | 12pm - 9pm
Saturday 17th October | 11am - 7pm
Sunday 18th October | 11am - 6pm
As part of ARTBLOCK, The Old Truman Brewery are proud to present British Artist Arran Gregorys immersive solo exhibition- HUNT.
Widely acclaimed for his geometric sculptures and experimental depictions of the natural world, HUNT is an exhibition of curious visual insight into the coexistence of man and nature.
Free Entrance from Brick Lane T2 Door
Facebook // Instagram // Tumblr
91 Brick Lane, London, E1 6QL 020 7770 6000
firstname.lastname@example.com | www.trumanbrewery.com
Copyright © 2012 The Old Truman Brewerysite maintained by Gunix Limited


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• Queer Fiction
• Kinky Erotica
• The Softer Side
• Quickies
• Flashers
• Poetry
The Best of 2014
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by Elliot DeLocke
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Life's Little Gifts
Self-centered Bastard
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By Helen E. H. Madden
The Goldfish Bowl
By Helena Settimana
So Much Better
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Porn Star
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A Round of Cheer
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Happy Birthday Mr....
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Fucking Money
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Happy Hour
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The Bathroom Mirror
Sleeping Ducks
Her new dress fit her nicely and she knew it. It was long and black and sleek. She wore only perfume underneath it. The feel of it, almost being naked in a room full of tuxedoed men and decked out women, the feel of it made her damp and tingly.
The dinner had been okay, not good, just okay, but the wine was well chosen for such a large crowd. The speakers had droned on, their jokes and stories dovetailed neatly and were packaged appropriately as simply not memorable.
So she sat naked beneath her new shiny black dress wondering if her husband would be awake when she called home from her room.
Her co-workers milled around her, some of them making plans for a drink on Beale Street. Julie wanted to go to B.B. King's club. Others wanted to avoid the crowd and look for a smaller out-of-the-way place. She didn't want to go, feeling like she'd rather be alone, or at least away from them for a while, so she said her goodnights and eased from the banquet room into the hall. She walked slowly toward the lobby and the elevators, considering a drink in the bar, thinking of the piano music, perhaps another glass of wine. She saw him then.
"Do I know you?" she asked, still smiling.
"No, I don't think so," he answered in a voice she thought she knew, "But would you like to?"
An odd reply, she thought, holding his eyes, his gaze. "Perhaps," was all she said.
"Then stay right here."
He walked to the lobby bar and bought two glasses of chardonnay. She watched him sign the charge to a room and it made her smile and blush when she realized what she'd thought. He came back to her and handed her the glass of wine without speaking.
"Have you ever been on the roof, where the ducks are kept?" he asked.
"No," she lied for some reason.
"I was just going to go up, would you like to come?"
"I'd like that," she told him, thinking only for a moment about the double meaning.
They walked together into the elevator and waited quietly as it carried them up to the roof. Obviously, she thought to herself, he knows of the ducks and their residency in the hotel. I wonder, she thought, if he's seen them march to the fountain in the lobby. She made a mental note to ask him but forgot it when she felt his body against hers, his hip against her hip, pressing there, not moving in the empty elevator they shared.
The ride ended and their hips separated as they stepped onto the roof and took in the lights of the city and the sky. The humid feel of the river so near them hung in the summer night air. He walked casually to the duck house, surrounded by a fence, and stood there looking.
"They're asleep, I guess."
"Yes," she answered.
"In the lobby," he began without looking at her, "Did you feel something when you saw me?"
She didn't know how to answer, so she didn't.
"Did you feel like we knew each other and that we were lovers?"
Again, she didn't answer.
He turned to her then, smiling into her eyes until she smiled back without thinking. He took her wine glass and set both of them on the park bench situated near the duck house. She was in his arms before she realized how, his lips on her neck, his hands low on the small of her back feeling no lines of clothing under her dress.
She closed her eyes as his kiss moved to her ear. The feel of his cock hard inside his jeans was electric, his hardness pressed against her stomach, low, just above her pubis. His mouth found hers and they kissed as his hands moved down to cup her ass through her dress. He drew her to him pressing his cock into her without any subtlety at all.
"Turn around and bend over," he whispered to her.
And she did. Slowly, but without any hesitation. She bent at the waist and rested her hands on the seat of the park bench where the wine glasses still sat. She could feel him moving behind her, moving down, she felt, until he was kneeling behind her. His hands moved up her legs, pushing her dress up, gliding it easily up her thigh high stockings, over the smooth skin of her thigh, up and over her naked ass until she was exposed to him there on the roof.
He reached for the wine glasses and took them both. She moved her feet to spread them more as he began to pour the wine down the crack of her ass, letting the liquid pass slowly over her, letting her pussy feel the cool kissing touch of the wine. When he leaned into her to lick the wine from her, the touch of his tongue sent a shiver of a hint, a shiver of an orgasm close within in her.
She did come when his tongue entered her. And he held her hips in his hands, pressing his face deeper between her legs, pressing his tongue deeper inside her, his chin hard against her clit.
As she drew in a breath and asked herself how all this had happened, he ran his tongue upward over her tight anus, licking the last of the wine from her there before he moved to stand. Her dress fell from where it had been gathered at her waist as she straightened to stand as well. He held her then from behind. Tightly. Quietly. And he kissed her neck as the ducks slept undisturbed. For her it felt as if it all had happened before. Odd, she thought, very odd.
The traffic on the streets below them made muted irregular sounds as they moved back toward the elevator together. She felt she knew how the night would end, but she wasn't sure so she kept an open mind.
copyright, 2000 J.D. Coltrane. All rights reserved.
Authors live for feedback!
Copyright 1996 and on, Erotica Readers Association, Inc.
By Nikki Isaak
Chrema's Game
Shagging Oozing ...
In The Soup
Silencing the Circling Echoes
Dreamrealms: blasphēmos
The Thief and ...
Demon Sunday
Undead Urges
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The Other Man
The Girl Who Taught...
Glowing In The Dark
Saturday Afternoon Confessions
Try it; You'll Like It
Shared Ride
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New Truck
Bug Hunt
The Stacks
By Valentine Bonnaire
It Came Upon a Mid...
Guys & Dolls
The Beautiful Kind
A Little Irish Honey
Vanilla Suede
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Earthquake Blowjob
Riding on the Metro
Reality Sucks
Whore's Borscht
One Winter Night...
El Padron
by Akosei
The Connection
by Alan
by Clover
Nothing Personal
by Dawn Wan D'Stylo
That Holiest Place
by G. Russell
The Village Church
by Ian D Smith
La Petite Mort
by Isabelle Carruthers
Sleeping Ducks
by J.D. Coltrane
by Jaelyn
Home Again
by Jean Roberta
In A Restaurant
by Jim Danner
Silk Appetizer
by Jude Mason
A Demure Slut
by Kevin Morken
Fucked by a Cucumber
by Lauren Mills
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by Randi Dixon
by Raziel Moore
Pattern Passion
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by Richard Raiment
In the Confessional
by TD Fallon


text: Adult Cat Finder by Free Britney at March 6, 2013 5:43 pm. Comments Adult Cat Finder. For all of you looking for some HOT feline tail online. This video is no longer available. Please check below for related videos. Edit Delete Follow LOL? Facebook Disqus Tags: LOL, Pets Related Videos: LOL Videos, Pets Videos Related Post: Adult Cat Finder: Looking For Some Hot Local Feline Tail?! Uploaded by: Free Britney Uploaded: March 06, 2013 Duration: 32 seconds


text: We're sorry, Printed Butterfly Baby Blanket is no longer available Why not try one of these instead? Star Fleece Baby Wrap by Tuppence and Crumble £25$54.17€36.99$41.13 Personalised Jacquard Knit Blanket by My 1st Years £30$65.01€44.39$49.35 can be personalised Personalised Blue Bunny Baby Comforter by My 1st Years £25$54.17€36.99$41.13 can be personalised Personalised Embroidered Baby Blanket by Broderie Blanc £25.50$55.25€37.73$41.95 can be personalised Printed Butterfly Baby Blanket by Union Jack and Jill £23.50$50.92€34.77$38.66 3 customer reviews(3) This item is no longer available £18.50$40.08€27.37$30.43 delivery to United States Receive this item 5-10 working days from dispatch International delivery available we're sorry we're sorry, This item is no longer available buy a gift voucher related categories baby & child > baby care > blankets, comforters & throws by Union Jack and Jill Location: Birmingham, GB read seller's profile see seller's complete range more items from this seller Oyster Spot Fitted Sheet £27$58.50€39.95$44.42 Child's Printed Butterfly Cushion Cover £24$52€35.51$39.48 Printed Butterfly Cot Bed Duvet Set £60$130.02€88.79$98.71 Butterfly Changing Pouch £7.50$16.25€11.09$12.33 Tractor Single Duvet Set £72$156.02€106.55$118.45 15% Off Tractor Pyjamas £17.43$37.77€25.79$28.67 view all you may also like PRODUCT DETAILS CUSTOMER REVIEWS DELIVERY RETURNS Made in Britain ask seller a question save for later A beautiful, soft printed baby blanket featuring our butterfly print. Our blankets are designed, printed and made in Britain. As soft as a babygrow, our products are made from 100% cotton interlock which is comfortable for your little one and washes well for grown ups. This contemporary print features delicate spotted butterflies in shocking pink fluttering over an oyster backdrop on one side and a oyster with white spot on the other. Our blankets are finished with a soft white binding in the same fabric. Perfect for your little one to keep warm and snug in their pram. made from: 100% cotton interlock. Machine washable at 40 degrees. dimensions: Size 75 x 75cm. product code: 183703 3 customer reviews Wed 19 Feb 2014 Beautiful product Sun 09 Jun 2013 A loverly product but expensive Mon 12 Nov 2012 No comment supplied. read about our product rating system ratings guide trusted independent customer feedbackforum excellent bad good poor This product is dispatched to you by Union Jack and Jill. MAINLAND UK order now and receive this item on or before price Standard Delivery Tuesday 13 October £2.75$5.95€4.06$4.52 Standard Courier Delivery Tuesday 13 October £3.95$8.55€5.84$6.49 NON-MAINLAND UK estimated delivery price Highlands & Islands of Scotland 2-5 working daysfrom dispatch £2.75$5.95€4.06$4.52 Northern Ireland 2-5 working daysfrom dispatch £2.75$5.95€4.06$4.52 Other UK Islands 2-5 working daysfrom dispatch £4.95$10.72€7.32$8.14 INTERNATIONAL DELIVERY estimated delivery price Western Europe 2-5 working daysfrom dispatch £11.50$24.92€17.01$18.91 Rest of Europe 5-10 working daysfrom dispatch £11.50$24.92€17.01$18.91 USA & Canada 5-10 working daysfrom dispatch £18.50$40.08€27.37$30.43 Asia & Australasia 5-10 working daysfrom dispatch £19.50$42.25€28.85$32.08 Rest of the world 5-14 working daysfrom dispatch £19.50$42.25€28.85$32.08 You have 28 days, from receipt of cancellable goods, to notify the seller if you wish to cancel your order or exchange an item. Please note: goods that are personalised, bespoke or made-to-order to your specific requirements, perishable products and personal items sold with a hygiene seal (cosmetics, underwear) in instances where the seal is broken are non-refundable, unless faulty. Read more about our returns policy.Should you choose to return or exchange your order you will need to deliver the item(s) to the UK, where this seller is based. Union Jack and Jill's return policy


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Palladium / Diamond
Palladium / Diamond
Palladium / Smoky Quartz
Palladium / Blue Sapphire
Palladium / Peridot
Palladium / Ruby
Palladium / Blue Sapphire
Palladium / Peridot
Palladium / Blue Sapphire / White Sapphire
Palladium / Amethyst / Rhodolite Garnet
Palladium / White Sapphire
Palladium / Tanzanite
Palladium / Green Amethyst / Diamond
Palladium / Green Amethyst / Diamond
Palladium / Citrine / Yellow Sapphire
Palladium / Green Tourmaline
Palladium / Yellow Sapphire / Citrine
Palladium / Aquamarine / White Sapphire
Palladium / Ruby / White Sapphire
Palladium / Emerald / Diamond
Palladium / Blue Sapphire / White Sapphire
Palladium / White Sapphire / Rock Crystal
Palladium / White Sapphire
Palladium / Iolite
Rings have long symbolized the circle of life. At Gemvara, we believe that the rings you wear should be one of a kind, like you. That's why our rings are made to order in your choice of conflict-free gems and recycled precious metals. Choose quartz and palladium or green amethyst and white gold: it's your choice. Mix and match gems and precious metals for a look that's exactly you. It's jewelry for all life's occasions, from an engagement or holiday to your own personal milestones and celebrations. Our unrivalled selection of designs by Just Like You Designs, Ji Hwang, Gemvara Essentials, and other talented jewelry designers means you can find a ring that's just your style. Because all Gemvara palladium oval rings are made to order, we can hand-select the finest quality materials to perfectly suit your design. Oval-cut gemstones have excellent brilliance and appear larger than the traditional round cut. Rare and naturally white, palladium is a platinum group metal that weighs a bit less than gold, making it versatile even for large jewelry designs. Be careful when removing rings to wash your hands. Don't leave your ring on the rim of a sink where it can slip down the drain! Clean palladium oval rings with mild dish soap: use a soft brush where dust collects. Gemvara's fine quality palladium oval rings are designed to be passed down for generations to come, crafted by hand in the United States.
We can help right away. Chat with a jewelry expert now!


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$50 of Food and Drink for Only $25 at Cruisers Bar
$50.00Retail Value
You will receive 2 - $25 certificates for $25!
For a large time with a small price, COME TO CRUISERS!!!
Map: Click here for map
Website: www.cruisersgj.com
The Fine Print
Denomination: $25.00
How many deals can I purchase? 4
Can deal voucher be used for alcohol? YES
Can be used at other locations? NO
Cash back for unused portion? NO
Use more than one deal voucher per visit? NO
Face value of deal voucher must be used at time of visit.
No cash value.
Tax and gratuity not included
Cannot be used for multiple visits.
Gratuity not included.
$50 of Food and Drink for Only $25 at Cruisers Bar
715 Horizon Drive, Ste 100
Grand Junction, Colorado 81506
Phone: www.cruisersgj.com


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- Shop
- Support
- Learn
- Explore
- Exhibitions
- Collections
- Library
- Connect
- Collaborate
- Genealogy
- Digital Scholarship
- Calendar
- Programs
- The Second Half: Lectures
- WJEC Grand Opening Celebrations
- 3rd Annual Haunted Whaleship
- Book Signing: "A Genius at His Trade"
- Film: "Most Likely to Succeed"
- Lecture Series: Whales in the Heart of the Sea
- Cartography Conference
- An Evening of Yoga & Music
- The GAEA Summit
- Annual Family Activities
- Community Programs
- Annual Events
- Moby-Dick Marathon
- Past Programs
- Visit
Join our crew of more than 3,000 members who enjoy and support our exhibitions, programs and special events.
Membership provides unlimited free admission year-round, so you can experience firsthand all that's new a the Museum. There is always something for you to see, learn or to explore time and again. Members also enjoy a 10% discount in our Museum Store.
To learn more about our membership program contact Caitlin McCaffery at (508) 997-0046 ext. 116 or firstname.lastname@example.com.
Cupola Society
Members have the opportunity to arrange personalized visits, enjoy VIP gatherings and special trips, plus view private collections.
Corporate Membership and Sponsorship
This program provides business with marketing opportunities, in addition to access to the Museum's collections, exhibitions and VIP networking events.


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LIM College Stats, Info and Facts
|Campus Setting:
|Large City
|Highest Degree Offered:
|Master's degree
|Level of Institution:
|Four or more years
|School Colors:
|Blue, Red & Purple
Choosing to attend LIM College has been the best decision I have ever made. I love the tight-knit community and industry experience that LIM offers. Every one is a familiar…
LIM is great, the internship/job opportunities are so amazing. I don't think there is another school out there that would allow me to gain so much knowledge and experience in…
The school is very modern and the teachers seem passionate about their jobs. You are surrounded by fashion where each building is located. The school is located on 5th Ave…
I attended the summer fashion course there last summer and ill say i had a blast! the dorms were very cozy. The people were very nice and helpful…
LIM College educates and prepares students in the businesses of fashion merchandising, visual merchandising, marketing and management through an integrated, experiential and creative approach utilizing the classroom, internships, and the fashion industry at large. LIM College fosters understanding of the relevant issues facing industry and the global community, engaging students in a concentrated professional program, while simultaneously providing them with a solid foundation in liberal arts.
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