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|C.J. Lee
Restructuring within Michigan Staff Leads to Internal Promotions
Restructuring within Men's Hoops Staff Leads to Internal Promotions
2012-13 Michigan Men's Basketball Roster
2012-13 Michigan Men's Basketball Roster
Behind the Scenes with the Wolverines: NCAA Final Four
Behind the Scenes with the Wolverines: NCAA Final Four
Final Four Press Conference
Final Four Press Conference
Behind the Scenes with the Wolverines: NCAA South Regional
Behind the Scenes with the Wolverines: NCAA South Regional
C.J. Lee begins his fifth season with the Wolverines serving as the Director of Program Personnel. He spent his first three years as the program's administrative specialist.
Lee, a two-year letterwinner for the Wolverines, returned to Michigan after completing work on his master's degree. Lee played in 67 games as a Wolverine and a 103 total in his collegiate career. After transferring to Michigan from Manhattan, Lee walked onto the Wolverines and earned a second semester scholarship as a senior and closed the year earning his bachelor's degree in political science.
Returning for his fifth-year (2008-09), Lee was awarded a full scholarship from Beilein, was named a co-captain and was an integral part in a Wolverine late-season run and subsequent return to the 2009 NCAA Tournament, where U-M advanced to the second round. This marked Michigan's first trip back to the NCAA Tournament in 10 seasons (1998).
Lee was named a Big Ten Outstanding Sportsmanship Award winner and was a Michigan Daily Student of the Year, one of 10 recipients. He closed his career recording his first career double-digit scoring performance with 11 points against Oklahoma in the NCAA second round. A two-time Academic All-Big Ten selection, Lee was awarded the Thad Garner Leadership Award twice, the Wayman Britt Outstanding Defensive Player (2009) and the Steve Grote Hustle Award (2008) by the program.
In May of 2010, Lee completed his master's degree in public policy from Michigan's Gerald R. Ford School of Public Policy. Lee graduate with his bachelor's degree in political science from U-M in 2008. While continuing to finish his master's following his final season, Lee worked for Michigan's Governor Rick Snyder on his campaign. He served as a travel aide and policy/communications staffer until April 2010.
Upon graduating, Lee worked at Ann Arbor SPARK. As a business development manager, Lee helped established companies maneuver the local and state business climate by connecting them to the resources designed to help them succeed.
Born in Saginaw, Mich., Lee spent much of his childhood in Lansing, Mich., until moving to New York State as a teenager and prepped at Pittsford Sutherland High School, earning varsity letters in basketball and football.
The C.J. Lee File
Born: October 17, 1985
Hometown: Pittsford, N.Y.
High School: Pittsford Sutherland High School
College: Michigan, 2008 (B.A., Political Science), Michigan, 2010 (MPP, Public Policy)
Career Resume
|University of Michigan
|Administrative Specialist
|University of Michigan
|Director of Program Personnel
» Learn about 2015-16 Michigan men's basketball ticket opportunities.
Irvin to Miss 6-8 Weeks Following Procedure
B1G Announces Dates, Matchups for Conference Slate
Our Venue Namesakes: Ocker, Oosterbaan
Men's Basketball Included in Ticket Policy Changes
Television, Tip Times Set for 2015 ACC/Big Ten Challenge
1970s Wolverines Hold Annual Golf Outing at Radrick Farms
Michigan Draws UConn to Open Battle 4 Atlantis


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September 18, 2013 - Industry News
Clean Energy Fuels Corp., Ferus Natural Gas Fuels, GE Ventures and GE Energy Financial Services announced a consortium to jointly deliver liquefied natural gas in the United States.
Tags: GE, Clean Energy, Liquefied Natural Gas, Natural Gas Fueling Station, Eagle LNG, Ferus Natural Gas Fuels
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
The expert, Mark Betner from CITGO, will answer your questions
The expert, Rence Oliphant from Hendrickson, will answer your questions
LockLight Indicates When a Lift is Safe
Diesel Fuel Test Takes 20 Minutes
CT50 Mobile Computer Offers Flexible Features
Accuride App Displays Products and Information

subset: commoncrawl


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Philadelphia Theatre Company to Open New Season with DISGRACED
by BWW News Desk - Sep 8, 2015
Ayad Akhtar's Pulitzer Prize-winning play Disgraced kicks off Philadelphia Theatre Company's 2015-2016 season, October 9 - November 8 at the Suzanne Roberts Theatre (Broad and Lombard Streets). Directed by Mary B. Robinson, the ensemble cast features Anthony Mustafa Adair, Ben Graney, Aime Donna Kelly, Monette Magrath and Pej Vahdat. (more...)
BWW's On This Day - September 26, 2015
by - Sep 26, 2015
Here are the Broadway, Off-Broadway and West End shows which opened on September 26 along with all of the upcoming show openings, closings and special events! (more...)
BWW Interview: 20th Anniversary of Actors Theatre's Dracula
by Keith Waits - Sep 21, 2015
Bram Stoker's Dracula has been a mainstay at Actors Theatre of Louisville (ATL) since 1995, and has become identified with actor/director William McNulty, who eight years ago was invited to forge his own adaptation of the horror classic. The result only intensified audience demand and acceptance, and the play now stands as the second holiday perennial (with A Christmas Carol) for Louisville's highly acclaimed regional theatre. This interview with Mr. McNulty was originally published in 2013 by Arts-Louisville.com, and covers Dracula as well as the veteran actor's long association with Actors Theatre. (more...)
Tom Stoppard's HAPGOOD to Play Hampstead Theatre This Winter
by BWW News Desk - Sep 14, 2015
Written by acclaimed playwright Tom Stoppard and directed by Howard Davies, Hampstead Theatre is delighted to present HAPGOOD, with previews commencing from Friday 4 December 2015 for an opening Wednesday 9 December at 7pm. The show will run through 16 January 2016. Full casting to be announced. (more...)
Geva Sets Festival of New Theatre 2015 Lineup
by BWW News Desk - Oct 7, 2015
Geva Theatre Center unveils its line-up for the Festival of New Theatre 2015 to be held in the Fielding Nextstage from October 21 - November 1. FONT 2015 is a vibrant and innovative mix of new works by some of the most exciting playwrights from across the country and around the corner and is part of Geva's ongoing commitment to developing and producing new work for the American theatre. (more...)
WORDS BY IRA GERSHWIN Extended Through 5/24 at Colony Theatre
by BWW News Desk - May 8, 2015
The Colony Theatre has announced that the final production of its historic 40thAnniversary season, the critically-acclaimed, smash-hit, Los Angeles Premiere of WORDS BY IRA GERSHWIN A Musical Play by Joseph Vass, directed by David Ellenstein, Musical Director Kevin Toney, Musical Arranger Joseph Vass will be EXTENDING through SUNDAY, MAY 24 at the Colony Theatre, 555 N. Third Street in Burbank. (more...)
Rubicon Theatre Sets Director, Cast for OTHER DESERT CITIES
by BWW News Desk - May 5, 2015
Rubicon Theatre Company Producing Artistic Director Karyl Lynn Burns today announced the director and cast for OTHER DESERT CITIES, Jon Robin Baitz's highly lauded story about a family in the public eye whose members must find a new way forward when each person's beliefs and illusions related to a pivotal family event are called into question. Filled with richly drawn characters, dramatic plot elements, and witty social commentary, OTHER DESERT CITIES garnered five Tony nominations and was awarded Outstanding Play by the Outer Critics Circle. The show takes its title from a sign off California's I-10 freeway where one continues on to Palm Springs or exits toward "Other Desert Cites." (more...)
Williamstown Theatre Festival Adds Late-Night Cabaret, Fridays@3 Reading Series & More to 2015 Season
by BWW News Desk - May 21, 2015
Williamstown Theatre Festival has announced further programming and special events to join the 2015 summer season including: the legendary Late-Night Cabaret, the ever popular Fridays@3 Reading Series, and this summer's Developmental Workshop Series. Also announced are this year's Boris Sagal and Bill Foeller Directing Fellows: Dustin Wills and Adrienne Campbell-Holt. (more...)
Rosie O'Donnell & More to Open Provincetown Dream Season During Memorial Day Weekend
by BWW News Desk - May 19, 2015
Summer 2015 kicks off with star-power in Provincetown this Memorial Day Weekend. Leading off for Producing Artistic Director Mark Cortale's inaugural Broadway @ Town Hall season is comedian-actress Rosie O'Donnell with Sirius XM radio star Seth Rudetsky as pianist and host, for one show only on Sunday, May 24 at 9:00 PM, and featuring opening guest, indie rocker Melissa Ferrick. Rosie's stage credits include the Broadway productions of "Grease," "Seussical," "Fiddler on the Roof," "Love, Loss and What I Wore," and the Encores! production of "No, No, Nanette." In addition to her acclaimed stand-up comedy and film careers, she is perhaps best known on television as the host and Executive Producer of the Emmy Award winning talk/variety series "The Rosie O'Donnell Show," and more recently for her return to daytime television as co-host of ABC's "The View." Memorial Day weekend also includes the one-two punch of Indie Rock star Melissa Ferrick back for her fifth consecutive season with two shows on May 23 at 6:30 PM & 9:00 PM, and the hysterical brand new drag comedy "Designing Women Meets The Golden Gals" starring Varla Jean Merman, Ryan Landry, Olive Another and Liza Lott will open for a summer-long run on May 23 and 24 at 7:30 PM (running through September 5). For Tickets visit www.ptownarthouse.com or call 800-838-3006. (more...)
BWW Reviews: Audra McDonald Shines at the Tilles Center
by Melissa Giordano - May 14, 2015
Audra McDonald Shines at the Tilles Center (more...)
Williamstown Theatre Festival Selects 2014 L. Arnold Weissberger Award Winner
by BWW News Desk - May 11, 2015
Williamstown Theatre Festival has announced that Abe Koogler's Kill Floor is the winner of the 2014 L. Arnold Weissberger Award. The play, which will premiere at Lincoln Center Theater's LCT3 this fall, will be introduced to audiences at a reading at Williamstown Theatre Festival on Friday, August 7 at 3:00pm on the Nikos Stage. Lila Neugebauer will direct both the reading and LCT3 production. (more...)
The Skivvies, Darrell Hammond & More Join Williamstown Theatre Festival's 2015 Lineup
by BWW News Desk - May 1, 2015
Williamstown Theatre Festival (Mandy Greenfield, Artistic Director) has added many exciting special events to their 2015 Season line-up. (more...)
New Musical ERNEST SHACKLETON LOVES ME to Close George Street Playhouse's Season
by BWW News Desk - Mar 25, 2015
George Street Playhouse and Artistic Director David Saint have announced that a new musical, Ernest Shackleton Loves Me, will close their current season, bowing April 22 and running through May 17, 2015. (more...)
Jake Broder, Elijah Rock and Angela Teek to Star in WORDS BY IRA GERSHWIN at The Colony, 4/15-5/17
by BWW News Desk - Mar 25, 2015
The Colony Theatre is thrilled to present the final production of its historic 40th Anniversary season, the Los Angeles Premiere of WORDS BY IRA GERSHWIN A Musical Play by Joseph Vass, directed by David Ellenstein, Musical Director Kevin Toney, Musical Arranger Joseph Vass. WORDS BY IRA GERSHWIN will preview on Wednesday, April 15; Thursday, April 16; and Friday, April 17 at 8:00pm. It will open on Saturday, April 18 at 8:00pm and continue through Sunday, May 17. (more...)
Jesse Tyler Ferguson to Lead THE TEMPEST, Lily Rabe & Hamish Linklater Set for CYMBELINE This Summer at SHAKESPEARE IN THE PARK
by BWW News Desk - Mar 19, 2015
The Public Theater announced additional casting today for the 2015 Free Shakespeare in the Park season, beginning Wednesday, May 27 at the Delacorte Theater in Central Park. This summer will feature Shakespeare's late romances with THE TEMPEST, directed by Tony Award nominee Michael Greif, and CYMBELINE, directed by Tony Award winner Daniel Sullivan. Jesse Tyler Ferguson will return to the Park this summer as Trinculo in THE TEMPEST, along with Hamish Linklater and Lily Rabe teaming up again with Daniel Sullivan on CYMBELINE to play Posthumus Leonatus/Cloten and Imogen, respectively. (more...)
SHIPWRECKED!, RED, ALWAYS...PATSY CLINE and More Set for WST's Independence Studio in 2015-16
by BWW News Desk - Mar 18, 2015
Walnut Street Theatre is thrilled to announce the 2015-2016 Independence Studio on 3 season. (more...)
SPAMALOT, THE LION, TO KILL A MOCKINGBIRD and More Set for Geva Theatre's 2015-16 Season
by BWW News Desk - Mar 16, 2015
Four productions still remain in Geva Theatre Center's 42nd Season: A Body of Water, Lee Blessing's play of memory and identity; The Mountaintop, a reimagining of Martin Luther King's last night on earth; the world premiere of Cass Morgan's journey to discover her roots - The Road to Where; and the season's grand finale, the laugh-out-loud comedy Vanya and Sonia and Masha and Spike. The 2014-2015 Season continued Geva's innovative efforts to connect patrons and artists and art with the community. The 2015-2016 Season will continue to build on that and also usher in a new era as Geva's historic home begins to undergo renovation and transformation. (more...)
BWW Features: Irish Success Stories at the Tony Awards
by Chris McCormack - Jun 8, 2015
When it comes to Irish theatre and the Tony Awards, the distance is never great. (more...)
Who Will Win the 2015 Tony Awards? We Compare Year By Year!
by BWW Special Coverage - Jun 6, 2015
The 69th Annual Tony Awards are this Sunday June 7th at 8/9c hosted by Kristin Chenoweth and Alan Cumming. It's the biggest award show of the Broadway season and it closes out a long award season for Broadway and Off-Broadway musicals and plays. We can't help but wonder what chances this year's Best Musical and Best Play nominees have of taking home the ultimate prize. (more...)
BWW Reviews: A CLOSER WALK WITH PATSY CLINE
by Jeffrey Ellis - Jun 5, 2015
That will also explain my rapturous response to the performance of A Closer Walk With Patsy Cline, a dramatized tribute to the country music superstar that opened at Dickson's Gaslight Dinner Theater on Thursday, June 4, running for a much-too-short two weekends at what was once known as The Renaissance Center. (more...)
Daniel Sharman, Jeremy Davidson, Glynn Turman Join Williamstown Theatre Festival's 2015 Season; Rehearsals Begin!
by BWW News Desk - Jun 15, 2015
Williamstown Theatre Festival (Mandy Greenfield, Artistic Director) kicked-off rehearsals for the first two productions of its 61stseason. Rehearsals are in full swing for the first two shows, Off the Main Road on the Main Stage, featuring Golden Globe and Emmy Award-winner Kyra Sedgwick in the World Premiere of a play by Pulitzer Prize-winner William Inge, and Legacy 0n the Nikos Stage, with Tony Award nominee Jessica Hecht and Drama Desk Award-winner Eric Bogosian in Daniel Goldfarb's World Premiere. Both casts arrive in the Berkshires ahead of performances that begin on June 30. (more...)
Christopher Shinn's AN OPENING IN TIME to Premiere at Hartford Stage This Fall
by BWW News Desk - Jul 31, 2015
Hartford Stage presents the world premiere of An Opening in Time by Pulitzer Prize finalist and Connecticut native Christopher Shinn, with direction by Oliver Butler of The Debate Society, from September 17 through October 11, 2015. An Opening in Time's central Connecticut setting is inspired by Shinn's hometown of Wethersfield. (more...)
WAKE UP with BWW 7/17/2015 - DRIVING MISS DAISY on TV, SOMETHING ROTTEN! CD and More!
by Jessica Showers - Jul 17, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? This weekend's big news: A new junior version of CHILDREN OF EDEN hits the stage, DRIVING MISS DAISY screens on PBS, two Broadway cast recordings are released and more! (more...)
George Street Playhouse Completes 2015-16 Season Slate with THE SECOND MRS. WILSON
by BWW News Desk - Aug 6, 2015
George Street Playhouse has announced that Joe DiPietro's The Second Mrs. Wilson, will occupy the previously to-be-announced slot in the New Brunswick theatre's 2015-16 season. (more...)
Audra McDonald and Will Swenson Lead Williamstown Theatre Festival's A MOON FOR THE MISBEGOTTEN, Starting Tonight
by BWW News Desk - Aug 5, 2015
Williamstown Theatre Festival's 2015 Season continues with an invigorating new look at Eugene O'Neill's A Moon for the Misbegotten, beginning tonight, August 5, and running through August 23, featuring six-time Tony Award-winner Audra McDonald and Tony Award-nominee Will Swenson. (more...)
WAKE UP with BWW 8/5/2015 - THE WIZ LIVE! Finds Dorothy, Cumberbatch in HAMLET, McDonald & Swenson in Williamstown & More!
by Jessica Khan - Aug 5, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? Today's big news: NBC's THE WIZ LIVE! has found its Dorothy, Benedict Cumberbatch becomes HAMLET at the Barbican, McDonald & Swenson take the stage in Williamstown and more! (more...)
Broadway Veterans Round Out Cast of Arena Stage's Reimagined OLIVER!
by BWW News Desk - Aug 28, 2015
Molly Smith directs her 30th production as Artistic Director of Arena Stage with a gritty and relevant take on the Tony Award-winning musical Oliver!, blending the chaotic worlds of 19th-century Victorian London with 2015 London. Smith's new in-the-round staging infuses a modern edge to the classic musical about an innocent orphan thrown into the dark world of double-dealing thieves and conmen, highlighting the disparity between classes and dangerous life on London's streets today. Featuring a remarkable score including 'You've Got to Pick a Pocket or Two,' 'Consider Yourself,' 'Where is Love?' and 'Food, Glorious Food,' Oliver! runs October 30, 2015-January 3, 2016 in the Fichandler Stage at Arena Stage at the Mead Center for American Theater. (more...)
Bristol Riverside Theatre to Stage BUS STOP, 9/29-10/18
by BWW News Desk - Aug 26, 2015
Bristol Riverside Theatre opens its 2015-2016 season with the classic romantic comedy Bus Stop by Pulitzer Prize-winner William Inge, running September 29-October 18. Directed by Susan D. Atkinson, the ensemble cast features Broadway veteran Mark Jacoby joined by Mike Boland, Linda Elizabeth, Barbara McCullough, Bruce Sabath, David Sitler, Grant Struble, and Jessica Wagner. (more...)
Kevin Spacey Returning to Broadway in Stage Adaptation of GOOD NIGHT, AND GOOD LUCK?
by BWW News Desk - Aug 26, 2015
'House of Cards' star and Broadway vet Kevin Spacey is planning his return to the Great White Way in a stage adaptation of director George Clooney's 2005 film GOOD NIGHT, AND GOOD LUCK. (more...)
Breaking News: Eugene O'Neill's HUGHIE Headed Back to Broadway Starring Forest Whitaker!
by BWW News Desk - Aug 24, 2015
This just in! BroadwayWorld.com has learned that the Academy Award, Golden Globe & BAFTA winning actor Forest Whitaker will make his highly anticipated Broadway debut in HUGHIE, by four- time Pulitzer Prize winner and Nobel Prize Laureate Eugene O'Neill. Directed by Tony and Olivier Award winner winner Michael Grandage, HUGHIE will play a strictly limited engagement in the spring of 2016 on Broadway at a Shubert Theatre to be announced. (more...)
BWW Interview: Audra McDonald Updates on P-Town Concert, Eye-Popping BEAUTY AND THE BEAST, SHUFFLE ALONG & More!
by Nicole Rosky - Aug 22, 2015
Audra McDonald has a big year ahead of her! After embarking on a concert tour this fall, the six-time Tony winner, who recenty wrapped filming for Disney's live action Beauty and the Beast, will be back on Broadway, starring alongside Brian Stokes Mitchell, Billy Porter, Joshua Henry and Brandon Victor Dixon in SHUFFLE ALONG. Before all of that, McDonald will head to Provincetown, MA to take part in the acclaimed Broadway @ Town Hall concert series, hosted by SiriusXM radio star Seth Rudetsky. For one show only on Monday, August 24 (6:30 PM), she will be joined onstage by her husband and fellow Broadway star Will Swenson, with whom she is currently starring in Williamstown Theatre Festival's A Moon for the Misbegotten. McDonald recently checked in with BroadwayWorld about Monday's concert, and updated us on all of her upcoming projects! Check out the full interview below: (more...)
Hottest Articles on BWW 8/11/2015 - 8/18/2015
by - Aug 18, 2015
Hottest Articles on BroadwayWorld.com 8/11/2015 - 8/18/2015. (more...)
Audra McDonald and Will Swenson Head to Provincetown This Month
by BWW News Desk - Aug 18, 2015
The acclaimed Broadway @ Town Hall concert series in Provincetown, MA, produced by Mark Cortale, will welcome Audra McDonald -- the historic 6-time Tony-winner and star of Broadway's LADY DAY AT EMERSON'S BAR AND GRILL, PORGY AND BESS, RAGTIME, MASTER CLASS and TV's PRIVATE PRACTICE -- for one show only on Monday, August 24 at 6:30 PM. She will be joined onstage by a very special guest, her husband and fellow Broadway star Will Swenson. (more...)
Matthew Broderick & Sarah Jessica Parker Perform Together in Provincetown Tonight
by BWW News Desk - Aug 17, 2015
The Art House in Provincetown, MA recently announced that Matthew Broderick and Sarah Jessica Parker will join his inaugural Broadway @ Town Hall series featuring SiriusXM radio's Seth Rudetsky as pianist and host for one night only tonight, August 17th. (more...)
Tom Pelphrey & Gordon Joseph Weiss Join Nina Arianda & Sam Rockwell FOOL FOR LOVE
by BWW News Desk - Aug 17, 2015
Lynne Meadow (Artistic Director) and Barry Grove (Executive Producer) just announced complete casting for Manhattan Theatre Club's upcoming Broadway premiere of Fool for Love by Pulitzer Prize winner Sam Shepard, directed by Obie Award winnerDaniel Aukin. (more...)
Regional Roundup: Top 10 Stories This Week Around the Broadway World - 8/14; GREY GARDENS, A MOON FOR THE MISBEGOTTEN and More!
by BWW Special Coverage - Aug 14, 2015
This week, we go around our Broadway World to feature stories in Boston, Long Island, St. Louis and more. Check out our top 10 stories around our Broadway World below, which include A Moon for the Misbegotten with Audra McDonald and Will Swenson in Boston, Bay Street's GREY GARDENS starring Betty Buckley and Rachel York, and The Muny's OKLAHOMA!, just to name a few. (more...)
WAKE UP with BWW 8/13/2015 - SPEED-THE-PLOW in Puerto Rico and More!
by Jessica Khan - Aug 13, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? Today's big news: JALA-LA-PALA -- aka SPEED-THE-PLOW -- starts in the Caribbean! (more...)
BWW REVIEW: Audra McDonald Dominates WTF's A MOON FOR THE MISBEGOTTEN
by Jan Nargi - Aug 12, 2015
There's no mistaking who's in charge in the Williamstown Theatre Festival's crackling production of A Moon for the Misbegotten now running through August 23. As Eugene O'Neill's indomitable Josie Hogan, six-time Tony Award winner Audra McDonald stomps, kicks, shoves and brandishes a big stick as she asserts her dominance over her father Phil (Glynn Turman), her landlord and wannabe love interest James Tyrone (Will Swenson), and anyone else who gets in her way. (more...)
Matthew Broderick & Sarah Jessica Parker to Perform Together in Provincetown
by BWW News Desk - Aug 12, 2015
Mark Cortale, Producing Artistic Director of The Art House in Provincetown, MA recently announced that Matthew Broderick and Sarah Jessica Parker will join his inaugural Broadway @ Town Hall series featuring SiriusXM radio's Seth Rudetsky as pianist and host for one night only on August 17th. Broderick and Parker will both sing and be part of an unforgettable evening that includes hilarious conversation and great songs. They have not appeared together on stage for nearly two decades since the Broadway revival of 'How To Succeed...' Parker actually began her career on Broadway in the title role of Annie and also starred in the Broadway musical 'Once Upon A Mattress.' Matthew Broderick is a two-time Tony Award winner for Neil Simon's 'Brighton Beach Memoirs' and for 'How to Succeed in Business Without Really Trying.' Sarah Jessica Parker won four Golden Globe Awards, three SAG Awards and two Emmy Awards as Carrie Bradshaw on the long-running HBO series 'Sex and the City'. The couple will be appearing for one night only in Provincetown on August 17th at 6:00 PM and 8:30 PM. The Broadway @ Town Hall concert series will benefit the Tyler Clementi Foundation. For Tickets visit www.ptownarthouse.com or call 800-838-3006. (more...)
Photo Flash: First Look at Audra McDonald, Will Swenson and More in WTF's A MOON FOR THE MISBEGOTTEN
by BWW News Desk - Aug 12, 2015
Williamstown Theatre Festival's 2015 Season continues with an invigorating new look at Eugene O'Neill's A Moon for the Misbegotten, now running through August 23, featuring six-time Tony Award-winner Audra McDonald and Tony Award-nominee Will Swenson. Check out a first look at the cast in action below! (more...)
Review Roundup: WTF's A MOON FOR THE MISBEGOTTEN, Starring Audra McDonald and Will Swenson
by Review Roundups - Aug 10, 2015
Williamstown Theatre Festival's 2015 Season presents an invigorating new look at Eugene O'Neill's A Moon for the Misbegotten, which opened on August 5, and runs through August 23, featuring six-time Tony Award-winner Audra McDonald and Tony Award-nominee Will Swenson. Let's see what the critics had to say... (more...)
Tony Winners Cherry Jones & Denis O'Hare to Announce 2015 Drama League Nominees Later This Month
by BWW News Desk - Apr 7, 2015
The Drama League has announced that Tony Award Winners Cherry Jones and Denis O'Hare will announce the 2015 Drama League Awards Nominees for Outstanding Production of a Play, Outstanding Production of a Musical, Outstanding Revival of a Play, Outstanding Revival of a Musical, and the much-coveted Distinguished Performance Award on Tuesday morning, April 21, 2015 at 11:00 a.m. at Sardi's (234 West 44th Street, 2nd Floor). (more...)
Los Angeles New Court Theatre to Stage ORPHANS, 4/17-26
by BWW News Desk - Apr 7, 2015
The Los Angeles New Court Theatre proudly presents... ORPHANS by Lyle Kessler. Directed by Samson Kohanski and starring Matthew Grondin, Nathan Burkart and Warren Davis (more...)
Matthew Broderick & Sarah Jessica Parker Headed to Provincetown This Summer
by BWW News Desk - Apr 28, 2015
Mark Cortale, Producing Artistic Director of The Art House in Provincetown, MA was thrilled to announce today that Matthew Broderick and Sarah Jessica Parker will join his inaugural Broadway @ Town Hall series featuring Sirius XM radio's Seth Rudetsky as pianist and host for one night only on August 17th. (more...)
Denis Arndt Replaces Kenneth Walsh in MTC's HEISENBERG; Rehearsals Begin This Week
by BWW News Desk - Apr 21, 2015
Manhattan Theatre Club's world premiere of Heisenberg, the new play by two-time Olivier Award winner Simon Stephens (The Curious Incident of the Dog in the Night-Time, Punk Rock), directed by Drama Desk Award winner Mark Brokaw (The Lyons, How I Learned to Drive) starring Denis Arndt (The Night Alive at Geffen Playhouse, "The Practice") and Tony and Emmy Award winner Mary-Louise Parker (Proof, "Weeds") begins rehearsals Thursday. (more...)
Bristol Riverside Theatre to Present AN ENEMY OF THE PEOPLE, 5/12-31
by BWW News Desk - Apr 20, 2015
Community and collaboration are the watchwords of Bristol Riverside Theatre's production of Henrik Ibsen's An Enemy of the People, running May 12-May 31. Co-directed by Susan D. Atkinson and Amy Kaissar, the high-voltage drama, which concludes BRT's Mainstage Season, features an ensemble of professional actors Keith Baker, Kevin Bergen, Mark Collmer, Brian Brillinger, Laura Giknis, Marc LeVasseur, Shamus Hunter McCarty, P. Brendan Mulvey and Sabrina Proffitt performing alongside Bucks County community members. The production is supported in part by a generous grant from PECO. (more...)
Cherry Jones Named Guest of Honor at Provincetown Tennessee Williams Theater Fest's Gala
by BWW News Desk - Apr 16, 2015
Celebrating its 10th Anniversary, the Provincetown Tennessee Williams Theater Festival, announced that multi-award winning stage and screen actor Cherry Jones will be the guest of honor of the Gala this year. In 2014, Jones was nominated for a Tony Award and won the Outer Critic's Circle award for her performance as Amanda Wingfield in the critically acclaimed Broadway production of Tennessee Williams' The Glass Menagerie. . (more...)
Estelle Parsons, Justin Long, Blair Underwood & More Join Williamstown Theatre Festival's Star-Studded 2015 Season
by BWW News Desk - Apr 16, 2015
Artistic Director Mandy Greenfield has announced additional casting for Williamstown Theatre Festival's Main Stage and Nikos Stage productions for the upcoming summer Season, which kicks off on June 30 and runs through August 23, 2015. (more...)
Where You Want to Spend Your Summer Vacation: Provincetown's Star-Studded Summer 2015 Season Announced!
by BWW News Desk - Apr 15, 2015
Mark Cortale, Producing Artistic Director of The Art House in Provincetown, MA, continues to raise the bar on already superb programming in this idyllic seaside Cape Cod town. (more...)
Berkeley Rep to Close Season with ONE MAN, TWO GUVNORS, Begin. 5/8
by BWW News Desk - Apr 10, 2015
Berkeley Repertory Theatre will conclude its 48th season with Richard Bean's internationally acclaimed One Man, Two Guvnors, a sassy update of Carlo Goldoni's classic knee-slapper, The Servant of Two Masters. Set in 1963 Brighton, England, One Man, Two Guvnors is a brilliantly delicious mash-up of splendid comedy, British pantomime, and music-hall revues. The uproarious plot features a disarming and doltish Francis Henshall who finds himself trapped by farce into working for two bosses - who are connected in wildly improbable ways. He just has to keep them from discovering each other. Inspired insanity, high-low antics, and nimble wordplay ensue - all backed by live musicians paying homage to rockabilly and a certain Fab Four. Directed by David Ivers - artistic director of the Utah Shakespeare Festival - and with songs by Grant Olding, One Man, Two Guvnors is a riotous blast complete with a colorful cast of characters in a topsy-turvy world of love triangles and mistaken identities. It previews on Friday May 8, 2015, opens on Friday, May 15, 2015, and plays through Sunday June 21, 2015. Press night for One Man, Two Guvnors will be held on Friday, May 15, 2015. Individual tickets start at $29 and can be purchased by phone at (510) 647-2949 or online at berkeleyrep.org. (more...)


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Belleza Day Spa and Hair SalonRead MoreWhether you're new to the day spa experience or an experienced vet, Belleza Day Spa and Hair Salon in Saint Helens has services to accommodate everyone. Keep those pores clear with a relaxing facial courtesy of the spa's expert aestheticians. Ease your sore and tense muscles with a relaxing and pain-free massage from this spa. Enjoy a relaxing hair makeover at this salon and leave feeling refreshed. Credit card payments are always accepted at this wonderful establishment. At Belleza Day Spa and Hair Salon, customers can easily find street parking or parking in a nearby lot. Relax away your problems at Belleza Day Spa and Hair Salon where any bad day is easily resolved.115 N 21st StSaint Helens, OR US
3rd Avenue SalonRead MoreDish about the latest gossip with a stylist at 3rd Avenue Salon in Scappoose while you receive a fabulous cut and color. This salon offers hair care for men, women and children of all ages. This salon offers the latest and hottest trends in nail fashion, including nail art. The massages at this salon stimulate circulation and reduce stress build up. This salon may be an appointment-only establishment, but they offer a wide range of time slots to suit your personal needs. If a trip to the ATM isn't on the agenda, visitors have the convenience of paying by major credit card. Your hair deserves the best hydrating treatment, and at 3rd Avenue Salon you can find it.33611 E Columbia AveScappoose, OR US
Fancy NailsRead MoreAfter a long week, a manicure and pedicure is exactly what you need. Check out Fancy Nails in Saint Helens for quality nail services. Style starts with a great set of nails. That's why this salon has manis and pedis available for you. This salon meets with its clients by appointment only, so make sure you schedule your service in advance. Put your mind at ease and your wallet away — Fancy Nails' services won't cost you more than other places. Fancy Nails understands some of us live in a cashless society. Guests are invited to pay with any major credit card. For a nail salon that's safe and stylish, Fancy Nails is at the top of its game.341 S Columbia River HwySaint Helens, OR US
It's All About YouRead MoreEach customer leaves happy at It's All About You's tanning salon in La Center. With services like no-chip gel manicures, pedicures, manicures, and nail art, you can keep your nails looking clean, fresh and trendy. Get that perfect bronze glow at this salon, including services such as tanning beds, spray tan, and airbrush tan. This facility provides clients with their choice of alternative services, including acne treatment. Every face has a different hairstyle that suits it best. Allow this salon's stylists to pinpoint the right one for you. Get a great bronze glow at It's All About You and start the weekend off looking hot, hot, hot.419 East Cedar AvenueLa Center, WA US


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Letter: Talks with Iran would suffer if Congress got involved
Published November 16, 2013 11:17 pm
This is an archived article that was published on sltrib.com in 2013, and information in the article may be outdated. It is provided only for personal research purposes and may not be reprinted.
Recent talks with Iran on limiting their nuclear program would be greatly hindered if our incompetent Congress tries to get involved ("Kerry: New sanctions on Iran could kill nuke deal," Tribune, Nov. 13).
Let us all hope that more responsible members help to temper Congress and let professionals make these negotiations during this critical and historic time.
Libya is an obvious example of how the current administration can handle international affairs.
Bill Stone
Park City
Reader comments on sltrib.com are the opinions of the writer, not The Salt Lake Tribune. We will delete comments containing obscenities, personal attacks and inappropriate or offensive remarks. Flagrant or repeat violators will be banned. If you see an objectionable comment, please alert us by clicking the arrow on the upper right side of the comment and selecting "Flag comment as inappropriate". If you've recently registered with Disqus or aren't seeing your comments immediately, you may need to verify your email address. To do so, visit disqus.com/account.comments powered by Disqus
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Layered, oval and marquise shape deep purple and amber prong-set rhinestones with a slight Aurora Borealis coating set in gold plated metal make up this drop dead gorgeous brooch which is unsigned, but is designer quality. It measures 2-1/4 inches by 2-1/4 inches. Although pre-owned, this brooch is in good pre-worn condition with some major plate wear and green spots on the back side (see photo), which is not visible from the front. There are no missing or loose rhinestones and the pin and clasp are secure.
1950s Deep Purple and Amber Rhinestones Layered Julianna Inspired Brooch
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2011 NFL Draft Pro Day Results
2011 Pro Day Results: March 8, 2011
Mike Blanc, DE/DT, Auburn
Height: 6-3. Weight: 281.
Projected 40 Time: 5.01.
Combine 40 Time: DNP.
Pro Day 40 Time: 5.00.
Benchx225: . Vertical: . Arm: .
Projected Round (2011): 6-FA.
Mike Blanc measured in an inch shorter than he was listed at Auburn. This hurts his chances of being drafted.
Kodi Burns, WR, Auburn
Height: 6-0. Weight: 206.
Projected 40 Time: N/A.
Combine 40 Time: DNP.
Pro Day 40 Time: 4.70.
Benchx225: . Vertical: . Arm: .
Projected Round (2011): FA.
Josh Bynes, ILB, Auburn
Height: 6-2. Weight: 240.
Projected 40 Time: 4.70.
Combine 40 Time: DNP.
Pro Day 40 Time: 4.80.
Benchx225: . Vertical: . Arm: .
Projected Round (2011): 5-7.
Josh Bynes' slow 40 could hurt him on Draft Day.
Antoine Carter, DE, Auburn
Height: 6-3. Weight: 259.
Projected 40 Time: N/A.
Combine 40 Time: DNP.
Pro Day 40 Time: 4.79.
Benchx225: . Vertical: . Arm: .
Projected Round (2011): FA.
Zach Clayton, DT, Auburn
Height: 6-2. Weight: 299.
Projected 40 Time: N/A.
Combine 40 Time: DNP.
Pro Day 40 Time: 4.87.
Benchx225: . Vertical: 33.5. Arm: .
Projected Round (2011): 7-FA.
Zac Etheridge, S, Auburn
Height: 5-11. Weight: 201.
Projected 40 Time: 4.59.
Combine 40 Time: DNP.
Pro Day 40 Time: 4.63.
Benchx225: . Vertical: . Arm: .
Projected Round (2011): 7-FA.
Nick Fairley, DE/DT, Auburn
Height: 6-4. Weight: 297.
Projected 40 Time: 4.95.
Combine 40 Time: 4.82.
Pro Day 40 Time: DNP.
Benchx225: . Vertical: 31. Arm: 34 3/4.
Projected Round (2011): Top 8 Pick.
Nick Fairley is back into the No. 2 pick conversation after a fantastic Pro Day. Fairley, now 297 pounds, showed tremendous footwork in the drills, prompting the ESPN3 crew to say that he looks like a 250-pound linebacker. Todd McShay, in particular, was overly giddy, going as far to say that he would be willing to carry Fairley's child.
Cameron Newton, Auburn
Scouting Report
Height: 6-5. Weight: 244.
Projected 40 Time: 4.64.
Combine 40 Time: 4.58.
Pro Day 40 Time: DNP.
Hand: 9 7/8.
Projected Round (2011): Top 3 Pick.
Prior to his Pro Day workout, Cam Newton approached Gil Brandt and said, "I let you down at the Combine. I'll make up for it today." Newton did just that, completing 50-of-60 passes in windy conditions. Three to five of the incompletions were drops. Todd McShay, a renowned Newton detractor, remarked that Newton really improved. It's really hard to imagine Newton falling out of the top three.
Demond Washington, CB, Auburn
Height: 5-8. Weight: 180.
Projected 40 Time: N/A.
Combine 40 Time: DNP.
Pro Day 40 Time: 4.43.
Benchx225: . Vertical: . Arm: .
Projected Round (2011): FA.
Terrell Zachery, WR, Auburn
Height: 5-11. Weight: 205.
Projected 40 Time: N/A.
Combine 40 Time: DNP.
Pro Day 40 Time: 4.44.
Benchx225: . Vertical: . Arm: .
Projected Round (2011): 7-FA.
Terrell Zachary is all about the number 4. He caught 44 balls in 2010 and ran a 4.44 at Auburn's Pro Day. He may have caught someone's attention.
Lee Ziemba, G/OT, Auburn
Height: 6-6. Weight: 317.
Projected 40 Time: 5.15.
Combine 40 Time: 5.47.
Pro Day 40 Time: 5.44.
Benchx225: 20. Arm: 34.
Projected Round (2011): 4-6.
Ryan Mallett, QB, Arkansas
Scouting Report
Height: 6-7. Weight: 247.
Projected 40 Time: 5.05.
Combine 40 Time: DNP.
Pro Day 40 Time: 5.36.
Hand: 10 3/4.
Projected Round (2011): 2-4.
Ryan Mallett had a fantastic Pro Day, prompting some of the NFL Network crew to speculate that he could be drafted in the first round. Mallett would be a top-five pick if it weren't for his lack of intelligence, arrogant attitude and "alleged" drug use.
Click here to see how this has affected the
2011 NFL Draft Prospect Rankings
2011 NFL Draft Pro Day Results:
Taiwan Jones
- 4/15
- 4/13
Harvard, Holy Cross
- 4/8
Notre Dame, Villanova
- 4/7
Boston College, Tandon Doss
- 4/6
Ras-I Dowling, Daniel Thomas
- 4/5
- 4/4
Iowa State
- 4/3
Hawaii, San Diego State, Southern Illinois
- 4/2
Da'Quan Bowers, Michigan
- 4/1
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- 3/31
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- 3/30
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Florida, Purdue, Delaware, Montana
- 3/15
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- 3/12
TCU, Oregon State
- 3/11
Nebraska, Mississippi State, Miami, Oregon, California, Portland State
- 3/10
Alabama, Wisconsin, Texas A&M, Oklahoma State, Colorado, Southern Alabama, Alabama A&M
- 3/9
Auburn, Arkansas
- 3/8
Wyoming, Lindenwood, Utah State, Weber State
- 3/7
Jerrel Jernigan
- 3/4
Baylor, Florida International, Tulane
- 3/3
2011 Pro Day Results
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Comment is free + Samuel Beckett
TV election debates: the new theatre of the absurdPeter BradshawI knew the whole 'I agree with Nick' show reminded me of something. Now I know what it was
A book that changed me Waiting for Godot taught me the difference between being smart and being intellectualNicholas LezardNicholas Lezard: A book that changed me: Samuel Beckett was irreverent yet profound, and able to sustain my interest despite nothing happening. I was mesmerised
A book that changed me Samuel Beckett's moving work taught me little French but much about loveNina Power
Nina Power: A book that change me: During a lonely summer in a Loire tourist office, How It Is conjured up the most wry descriptions of human capacity
Cartoon Beckett reimaginedChris Riddell
Chris Riddell on the coalition's approach to growth
The joy of not getting itMichael Billington
Michael Billington: Making esoteric art more accessible should not result in a dilution of the artist's original vision
Not only Beckett's birthdayAriel Dorfman
Ariel Dorfman: Samuel Beckett and Adolf Eichmann never met. But they were born a month apart in 1906.
Champion of ambiguityTerry EagletonThis year's calendar to celebrate Beckett's 100th anniversary is crammed with literary events celebrating the life of the modern age's most lovable pessimist, most of them, one imagines, awash with talk of the timeless human condition portrayed in his work.Nothing could be further from the truth, says Terry Eagleton.


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On the heels of the landmark decision by the Supreme Court in favor of gay marriage, the EEOC held on July 15, 2015 that sex discrimination under Title VII includes discrimination on the basis of sexual orientation. Even though the decision is not binding precedent in federal court, and runs contrary to a significant body of case law holding that Title VII does not prohibit discrimination on the basis of sexual orientation, it could be regarded by some courts as persuasive authority. The decision could also have an impact on employers in the form of an increased number of administrative charges of discrimination filed with the EEOC based on sexual orientation, as courts determine whether to adopt the EEOC's interpretation.
Tag Archives: EEOC
The Gay Marriage Decision: Support for Title VII Employment Discrimination Claims?
Following the excitement of the same-sex marriage decision by the U.S. Supreme Court on June 26th, the question remains how much the Opinion may impact Title VII employment discrimination claims. Based on our reading of the Obergefell v. Hodges decision, and the many states that have passed legislation protecting employees from sexual-orientation discrimination, we recommend that employers revisit and update their anti-discrimination policies.
Emergence of Transgender Status Issues in Workplace Raises Compliance Questions for Employers
Transgender issues have been grabbing headlines in recent months—perhaps most notably with Bruce Jenner's televised announcement about his gender transition. Beyond the bright lights of pop culture, a wave of litigation and legislation is causing employers to pay closer attention to transgender discrimination and related issues. As we noted in August of last year, there is an increasing trend toward protecting gender identity and transgender status. This post provides an update and a high-level overview of the landscape in this emerging area and offers some tips for employers to minimize risk.
Is Your Wellness Program Healthy? EEOC Provides Much Needed Guidance in Proposed Rule
On April 16, 2015, the Equal Employment Opportunity Commission (EEOC) issued a proposed rule addressing how the Americans with Disabilities Act (ADA) applies to wellness programs that are part of group health plans and that include medical examinations or questions about employees' health. Although not final and still open for public comment, this proposed rule provides important guidelines for employers in administering wellness programs.
Global Employers: How Are You Managing Workplace Concerns About Ebola?
While the world moves quickly to contain the Ebola virus, businesses across the globe are scrambling to figure out how best to manage workplace concerns and protect their employees. But as employers develop their Ebola response strategies, they should also be mindful of employee privacy, anti-discrimination, and other employment laws and regulations.
Three Key EEO Cases to Watch on the SCOTUS Docket This Term
The Supreme Court is set to weigh in on several key questions for employers this term related to employee discrimination. When does an employer have to accommodate a pregnant employee? How about a job applicant who wears a head scarf in an interview but does not make it clear she is doing so for religious reasons and needs an accommodation? Can a court decide whether the EEOC has done enough to resolve your case? Here are three key EEO cases to keep your eye on in the coming months. Read More
EEOC Won't Get its Prescription Filled at CVS: Case Challenging its Releases Dismissed on Summary Judgment
On October 7th, a federal district judge granted summary judgment against the U.S. Equal Employment Opportunity Commission (EEOC) in its lawsuit against CVS. The EEOC had challenged the nation's largest integrated provider of prescriptions and health-related services for its employee separation agreement. The EEOC's Chicago office had filed the suit in February, alleging the company's separation agreement violated its employees' Title VII rights to communicate with the EEOC and file discrimination charges. Read More
Let's Talk About Sex: U.S. Department of Labor Targets Transgender & Gender Identity Discrimination
On Tuesday, August 19, 2014, the U.S. Department of Labor issued a directive to "clarify that existing agency guidance on discrimination on the basis of sex . . . includes discrimination on the bases of gender identity and transgender status." This directive follows President Obama's Executive Order 13672, issued on July 21, 2014, amending existing orders to specifically prohibit federal contractors from discriminating based on gender identity.
Home Sweet Home: 6th Circuit Rules that Showing up for Work is not Required
Changes in telecommuting practices may be around the corner for many employers, as the recent 2-1 decision in EEOC v. Ford Motor Co., 2014 FED App. 0082P (6th Cir. 2014) may usher in significant changes in what constitutes a reasonable accommodation for an employee with a disability under the ADA. According to the Sixth Circuit, given the advances in technology, employers need to be more open to telecommuting arrangements and cannot assume that coming to work is always an essential job function. But the U.S. Chamber of Commerce warns—in an amicus brief filed in early June—that these changes may have a "devastating" effect on employers by allowing employees to choose "where and when" they want to work. Read More
The EEOC Takes Aim, Once Again, at Employers' Separation Agreements
On April 30, 2014, the U.S. Equal Employment Opportunity Commission filed suit against a private college, charging for the second time in two months that an employer's severance agreement was unlawful. The EEOC alleged that CollegeAmerica, Inc.'s Separation and Release Agreements violated federal law by conditioning the receipt of severance payments and benefits on the employee's promise not to file a charge with, or cooperate in investigations by, the EEOC against CollegeAmerica. Read More


text: Liverpool Archive 07 Jul 2013 Suarez to Chelsea? Pull the other one! By admin Chelsea News, Chelsea opinion, Chelsea rumours, Chelsea Transfer News, Premiership News 33 Comments Reports today from Spain are linking Chelsea with a bid of £30 million plus for Luis Suarez, and the story seems to be gathering pace in England. The Uruguayan is desperate to leave Liverpool, while the media seem to have decided that we are desperate for a striker. 2 + 2 = 17. There is Read More 23 Apr 2013 Liverpool won't sell Suarez and the PM wants him punished! By admin Chelsea game review, Chelsea News, Chelsea opinion 0 Comment The disgusting behaviour of Luis Suarez towards the Chelsea defender Branislav Ivanovic has had the whole world up in arms, and even the British Prime Minister David Cameron has made a statement implying that he expects a heavy punishment for the Uruguayan idiot. He said through a government spokesman: "It is rightly a matter for Read More 23 Apr 2013 Petr Cech – Chelsea players need to relax between crucial games By admin Chelsea game review, Chelsea News, Europa League News 0 Comment Petr Cech was very disappointed to concede the equalising goal to Liverpool on Sunday, especially as we were leading until the 97th minute, but he says that now the Chelsea players need to relieve the ongoing pressure ahead of every game by taking a relaxing break in between matches. Cech said: "'We are in a Read More 22 Apr 2013 Benitez blames referee for Chelsea dropping two points By admin Champions League News, Chelsea game review, Chelsea News, Premiership News 3 Comments The Chelsea interim manager Rafael Benitez certainly had an incident packed return to Anfield yesterday, and although everyone is talking about the disgusting behaviour of Luis Suarez, Benitez is wondering why on earth the referee kept playing after the 90 minutes to give Liverpool every chance to get an equalizer. He was obviously asked about Read More 22 Apr 2013 Juan Mata very disappointed that Chelsea didn't get all three points By admin Chelsea game review, Chelsea News, Premiership News 2 Comments the stage is set for a nail-biting end to the season for the fans of Chelsea, Tottenham and Arsenal, and Juan Mata thinks that Chelsea should have had all three points against Liverpool after leading right up until the 97th minute of the unusually extended game. Mata said after the match: "A point is a Read More 22 Apr 2013 Absolute nutter Luis Suarez should be banned for life! By admin Misc 0 Comment The Uruguayan striker Luis Suarez proved yet again that he is an absolute animal and should not be allowed to play in any competitive football match ever again. His totally unprovoked attack on Branislav Ivanovic in yesterdays game at Anfield was a vicious act, and his disgusting play-acting afterwards only compounded his guilt and emphasised Read More 18 Apr 2013 Chelsea spank Fulham to go favourites for top four (with highlights) By admin Champions League News, Chelsea game review, Chelsea News, Chelsea opinion, Premiership News 0 Comment Because Chelsea were playing their third big game in six days and the fact that it was a local derby against Fulham, it was expected to be a tough test for Rafa Benitez and the Blues at Craven Cottage last night. It turned out to be anything but, as we eased to a 3-0 win Read More 17 Apr 2013 Chelsea MUST take advantage of Arsenal's slip By admin Champions League News, Chelsea News, Chelsea opinion, Chelsea previews, Premiership News 0 Comment Chelsea have the perfect opportunity to put the disappointment of the FA cup exit at the hands of Manchester City behind them. Despite a back breaking fixture pile up, the Blues have got the chance to lay down a marker for a top four finish, after Arsenal failed to beat Everton last night. We travel Read More 22 Feb 2013 Is it time up for Torres at Chelsea? By admin Chelsea News, Chelsea opinion, Chelsea Transfer News, Premiership News 0 Comment The Chelsea manager Rafa Benitez came to the defense of Fernando Torres after the Spanish striker had another difficult night in the Blue of Chelsea. He missed a number of chances and his whole game seemed off against Sparta Prague, and the Blues were only rescued from extra time by a last minute Eden Hazard Read More 16 Feb 2013 Chelsea have ruined Torres says Benayoun By admin Champions League News, Chelsea News, Chelsea opinion, Chelsea Transfer News 5 Comments Fernando Torres has not exactly been the player that Chelsea were hoping for when they signed him from Liverpool for a British record of £50 million in January 2011. It took him over 900 minutes on the pitch to score his first goal for Chelsea which was his only goal from 18 games in that Read More 1234Next ›Last »


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Holiday cottage in Calstock
Calstock / Harewood
Cottage / 1 Bedroom / sleeps 2
2 Nights min stay
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Key info:
- Beach / lakeside relaxation
- Not suitable for children
- Car not necessary
- Pets welcome
- Private garden
6 May 2015
This really is a most wonderful place. So quiet and peaceful with amazing views across the valley and lovely walks around the old mine and amongst the trees. It feels like it's away from everything a… More
Thank you for your review of The Count House. We're pleased to hear that you enjoyed the tranquility and views at Okel Tor, and the convenience of Calstock. We hope to see you again!
13 Apr 2015
"Peaceful, rural getaway"
We stayed at the cottage for a weekend to celebrate my husbands birthday. Nick & Greg were fantastic hosts and were very helpful from booking through to making us feel welcome when we were staying the… More
We're delighted you enjoyed your weekend at The Count House and we look forward to welcoming you back!
12 Apr 2015
"A little piece of heaven"
Wow is really all I can say, after returning from a few nights in the Count House. This really is a perfect place for some time away from everything. We spent each morning eating breakfast outside on … More
Thank you for your review. We're pleased to hear you enjoyed your stay and liked the views and tranquility at Okel Tor and the local walks and pubs. We look forward to welcoming you back!
Cottage rental in Calstock
Calstock / Harewood
Cottage / 1 Bedroom / sleeps 2
2 Nights min stay
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Key info:
- Beach / lakeside relaxation
- Nearest beach 37 km
- Not suitable for children
- Car not necessary
- Pets welcome
- Private garden
20 Mar 2015
"So relaxing"
Just spent a very relaxing 4 days at The Smithy with my husband and 2 dogs. Great walks along the river Tamar to the local village pub and around the Okel Tor Mine grounds. Lovely log fire and comfort… More
Thank you for your review of The Smithy. We're glad to hear you had a relaxing stay and were able to see the eclipse! We hope to see you again soon!
19 Feb 2015
"A beautiful peaceful hideaway overlooking the River Tamar"
A magical location on the wooded banks of the Tamar. It's a beautiful spot, and with only the owner Nick, and the small Count House for neighbours, it is a peaceful place to be. Well organised, clear … More
Thank you for your review and kind recommendation. We're pleased to hear that you had everything you needed for an enjoyable and peaceful stay.
31 Aug 2015
"Wonderful peaceful hideaway"
The Smithy is a wonderful get-away-from-it-all place but with pubs, shops and amenities only a short walk away in Calstock. The views are simply stunning and despite the (relative) proximity of the ot… More
Holiday home rental
Cornwall / Calstock
House / 4 Bedrooms / sleeps 8
Short stays welcome
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£491 - £1188 / week
Key info:
- Suitable for children age 5+
- No pets allowed
- Private garden


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If you are associated with Arcola Health and Rehabilitation Center , click the Claim Listing button to contact a representative about a free listing with our referral program.
User Reviews
Description of Arcola Health And Rehabilitation Center in Silver Spring, MD
Number of Beds : 158
Arcola Health And Rehabilitation Center, located in Silver Spring, Maryland provides the following services: Nursing Home and Short Term Care: Rehabilitation, Respite. It accepts the following payment methods: Medicare, Medicaid, and Veteran's Benefits. Arcola Health And Rehabilitation Center has received 4 stars from Medicare and an average user review rating of 2 stars. Arcola Health And Rehabilitation Center has a very good hospital, Holy Cross Hospital, located nearby, which scored a 93 out of 100 in its most recent Medicare review. The Arcola Health And Rehabilitation Center's nearest hospital is 1 miles away. The zipcode (00000) in Maryland, where Arcola Health And Rehabilitation Center is located, has an above average safety rating based on recent crime statistics. A more detailed description of the types of care for Arcola Health And Rehabilitation Center can be found here.
Arcola Health and Rehabilitation Center is a nursing home. It provides medical nursing service for seniors with serious illnesses or disabilities twenty-four hours a day, delivered by registered nurses, licensed practical nurses, and certified nurse aids.
Nursing care facilities cater to several types of patients: some patients require short-term rehab while recovering from surgery; others require long-term nursing and medical supervision. In addition, some nursing homes offer specialized care programs for Alzheimer's or other illnesses, or short-term respite care for frail or disabled persons when a family member requires a rest from providing care in the home. Please note that you can help compare nursing homes by looking at the Medicare ratings of a given facility (Medicare has a 5-star rating system for comparing nursing homes). There are various ways for paying for care in a nursing home. Make sure you know your loved one's Medicare and Medicaid eligibility, and understand how you can use tools like long term care insurance to pay for nursing home care.
As one of the Nations Leading providers of Long Term Care and Transitional Care Services, our goal is to maximize physical wellness, promote independence, and to enhance personal dignity. We also provide individualized medical needs for all of our residents. 7 days a week we offer social activities of all types from STR to Dementia dx residents.
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Hey M Girls,
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Page 1
Joint Bone Spine 80 (2013) 70–76
Available online at
Original article
Impairment of two types of circulating endothelial progenitor cells in patients
with glucocorticoid-induced avascular osteonecrosis of the femoral head
Chao Chena, Shuhua Yanga,∗, Yong Fenga, Xinghuo Wua, Dong Chena, Qian Yua, Xiaohong Wanga,
Jing Lib, Juan Chenc
aDepartment of Orthopedics, Union Hospital, Tongji Medical College, Science and Technology of Huazhong University, Wuhan 430022, China
bDepartment of Integrated Traditional and Western Medicine, Tongji Hospital, Tongji Medical College, Science and Technology of Huazhong University, Wuhan 430030, China
cDepartment of Clinical Oncology, The University of Hong Kong, Pokfulam, Hong Kong, China
a r t i c l ei n f o
Article history:
Accepted 22 February 2012
Available online 13 April 2012
Avascular osteonecrosis
Endothelial progenitor cells
Endothelial colony forming cells
a b s t r a c t
Objectives: ThisstudyexaminedwhetherabnormalitiesofearlyEPCsandendothelialcolonyformingcells
of the femoral head (ANFH).
Methods: Early EPCs and endothelial colony forming cells (ECFCs) were obtained from 33 patients with
glucocorticoid-induced ANFH and 33 age- and sex-matched control subjects. Cells were isolated, in vitro
cultured and studied by Flow Cytometry and Immunofluorescence. Colony-forming unit counts were
observed from 33 patients and 33 healthy controls. Growth kinetics, migratory capacity to multiple
chemo-attractants, in vitro tube formation capacity and cytokine (vascular endothelial growth factor
and stromal cell-derived factor-1) levels in supernatants of two types of EPCs were assayed in ANFH
patients and matched controls (n=4).
Results: Mean numbers of colonies formed by both types of EPCs were decreased in ANFH patients (Early
EPCs: 2.42±1.46 versus 4.52±2.00, p<0.05; ECFCs: 0.62±0.55 versus 1.12±0.82, p<0.05,). Early EPCs
from ANFH patients showed impaired migratory capacity (63.8±11.7 versus 152.3±12.4, p<0.001) and
VEGF secretion (50.8±7.2pg/ml versus 62.8±10.1pg/ml, p<0.05). ECFCs from ANFH patients showed
decreased tube formation capacity (7.1±2.7 versus 23.8±4.3, p<0.001) and proliferation.
Discussion: Early EPCs and ECFCs were impaired in number and function in GC-induced ANFH, and their
distinct reduced capacity profiles might reflect different roles they played in endothelial dysfunction of
GC-induced ANFH.
© 2012 Published by Elsevier Masson SAS on behalf of the Société Française de Rhumatologie.
1. Introduction
Practically avascular osteonecrosis of the femoral head (ANFH),
which represents a devastating condition with a poor prognosis, is
a debilitating skeletal disorder affecting especially young patients
in their third to fifth decades of life. Avascular osteonecrosis, oth-
erwise known as aseptic necrosis of bone, results from multiple
pathological conditions including ischemia, osteocyte apoptosis
and necrosis, impaired vascular repair and subsequent loss of
structural integrity of the articular surface, thus finally leading to
significant clinical morbidity [1]. The most common cause of ANFH
is trauma, and the main cause of non-traumatic ANFH is the use of
glucocorticoid (GC). Although numerous investigators had postu-
lated several mechanisms involved in ANFH, the exact etiology and
∗Corresponding author. Tel.: +86 02 78 53 51 627; fax: +86 02 78 57 18 159.
E-mail address: firstname.lastname@example.com (S. Yang).
pathophysiology of GC-induced non-traumatic ANFH still remains
poorly understood.
Recently, growing evidences indicate that microcirculatory dis-
ANFH [2]. Regional endothelial dysfunction due to continuous
exposure to GC in femoral heads results in various disorders such
as aberrant vasoactive substances levels, decreased blood flow,
endothelial cells apoptosis, microcirculatory thrombus formation,
functional microvessels rarefaction, inhibition of angiogenesis and
finally osteoblasts and osteocytes death [3]. Therefore, this has
prompted investigations on the role of endothelial cells and more
importantly, its progenitors – endothelial progenitor cells (EPCs) in
GC-induced ANFH.
EPCs initially described by Asahara et al. [4] are now being
broadly investigated because of its significant role in vascular
different disease states and cardiovascular risk [5,6]. Thus, a num-
ber of studies have already implied EPCs as a surrogate biomarker
1297-319X/$ – see front matter © 2012 Published by Elsevier Masson SAS on behalf of the Société Française de Rhumatologie.
Page 2
C. Chen et al. / Joint Bone Spine 80 (2013) 70–76
in vascular dysfunction [7]. Our previous study also had found the
relationship between EPCs and ANFH [8].
However, recent studies indicated that there was another
newly so-called endothelial colony forming cells (ECFCs) or late
outgrowth endothelial progenitor cells (OECs) demonstrate highly
proliferative potential, exhibit self-renewal capacity and are capa-
ble of de novo vessel formation in vivo. In contrast, the early EPCs
(also known as colony-forming unit endothelial cells or CFU-ECs)
expressing hematopoietic markers lack the proliferative capacity
characteristic of true progenitor cells, fail to form vascular net-
are actually hematopoietic-derived monocytes manifesting some
angiogenic properties [11]. And it seems that ECFCs may serve as a
potential cell source more effectively for cellular therapies aiming
to enhance neovascularization in ischemic area.
Taken together, there is a lack of detailed data concerning the
tioned whether alterations of ECFCs existed in GC-induced ANFH.
Considering significant debate remains about the identity of EPCs,
we conducted a study to investigate the levels of early EPCs and
ECFCs and compared their functions in GC-induced ANFH patients
and age- and sex-matched control subjects.
2. Methods
2.1. Study population
The study population consisted of 33 patients (24 men, 9
women; mean age 42.7 years, ranging from 24-53 years) with
GC-induced ANFH, who were recruited in our hospital (Union Hos-
pital, Wuhan, China) from July 2008 to December 2010, and 33
age- and sex-matched control subjects, who were healthy volun-
teers. Clinical characteristics for all participants were summarized
in Table S1, Supplementary data. ANFH was diagnosed by radiog-
raphy and magnetic resonance imaging (Steinberg stage I to stage
IV). Exclusion criteria were cancer, pregnancy, diabetes mellitus,
impaired renal function and presence of cardiovascular diseases.
Patients with a demonstrable history of direct injury of the hip
were also excluded. This study was approved by the local ethics
committee and written informed consent was obtained from all
2.2. Preparation of mononuclear cells
Peripheral blood sample (60mL) was collected in heparin
sodium tubes from each patient. After density gradient centrifu-
gation, Buffy coat mononuclear cells (MNCs) were collected and
washed three times in PBS with 2% fetal bovine serum (Hyclone,
Logan, UT). MNCs were re-suspended in EGM-2 medium (Lonza,
San Diego, CA), half of which were used to culture ECFCs and the
other to culture early EPCs.
2.3. Culture of early EPCs
MNCs were seeded on tissue culture plates precoated with
fibronectin (BD Biosciences, Bedford, MA) in EGM-2 medium. After
collected and replated at 1×106cells/well onto fibronectin-coated
24-well plates. Growth medium was changed every three days.
Early EPCs colonies were identified as elongated sprouting cells
radiating from a central cluster of round cells and enumerated
2.4. Culture of ECFCs
ECFCs were cultured according to the protocol of Ingram DA
et al. [10]. ECFCs colonies that appeared between 7 and 30
days of culture were identified as well-circumscribed monolay-
ers of cobblestone-appearing cells and enumerated blindly by two
independent investigators on day 14 by visual inspection under
microscope. Subconfluent cells were trypsinized and replated onto
75-cm2tissue culture flasks coated with type I rat tail collagen (BD
Biosciences) for further passage.
2.5. Flow cytometry analysis
and resuspended in PBS. Then 0.5-1.0×106cells were incu-
bated with conjugated antibodies CD133-Allophycocyanin (APC)
(eBioscience, San Diego, CA) and VEGFR2-Peridinin chlorophyll
protein-Cy5.5 (PerCP-Cy5.5) (Biolegend, San Diego, CA) for 20min
at 4◦C away from light. Isotype-identical antibody served as
negative controls. Cells were analyzed using a Beckman Coulter
FC500 flow cytometer equipped with the Cellquest software pro-
gram. Light scatter profiles were collected on the cells using two
electronic gates to discriminate lymphocytes and monocytes in
accordance with previous reports [12]. Results were expressed as
percent of double positive cells.
2.6. Immunofluoresence of ECFCs
ECFCs at early passages (p2 or p3) were plated on type I rat
tail collagen. When reaching 80–90% confluency, cells were fixed
in 2% paraformaldehyde for 20min, followed by permeabilization
with 0.1% Triton X-100. After that, cells were blocked in 10% nor-
mal goat serum and then incubated with primary antibodies at
4◦C overnight. Primary antibodies were diluted as follows: rabbit
antihuman CD31 1:100 (Abcom, Cambridge, UK), rabbit antihu-
man VWF (Von Willebrand Factor) 1:200 (Abcom). Subsequently,
the cells were incubated with goat antirabbit secondary antibody
conjugated to fluorescent isothiocyanate (FITC) and then in 4?,6-
diamidino-2- phenylindole dihydrochloride (DAPI, sigma, St. Louis,
MO) for nuclear staining. Images were obtained using an Olympus
FV500 confocal laser-scanning microscope.
2.7. Uptake of DiI-Ac-LDL and binding of UEA-1 lectin
Both early EPCs and ECFCs were incubated with 2.4?g/mL
Dil-Ac-LDL (Introvogen-Molecular Probes, Eugene, OR) in EGM-2
medium at 37◦C for 4h. Then cells were washed with PBS, fixed in
4% paraformaldehyde, and further incubated with 10?g/mL FITC-
slides were washed with PBS before visualization under confocal
laser scanning microscope.
2.8. Growth kinetics of early EPCs and ECFCs
and four age- and sex-matched controls were enumerated at the
first passage using a trypan blue assay. Then cells were replated
to six-well plates at 1×105/well in EGM-2 and allowed to attach
hemocytometer every three days. Each experiment was performed
in quadruplicated. To make a growth kinetics curve, population
doubling time (PDT) were determined according to the equation:
PDT=T×lg2/lg (Nt/N0), where T was the time interval between
Page 3
C. Chen et al. / Joint Bone Spine 80 (2013) 70–76
each passage, N0was the number of cells seeded and Ntwas the
number of cells at harvest.
2.9. In vitro tube formation assay
Matrigel (BD Biosciences) was used to assess vascular tube
formation according to the manufacture's instructions. In brief,
1×104/well ECFCs at passage 2–3 or early EPCs at day 7 were
placed on top of Matrigel in 96-well plate and incubated at 3◦C for
48h. Cells were observed every 4h under microscope. The number
of closed network units formed by cells in 4 wells was manually
2.10. Migration assay
Early EPCs and ECFCs were detached and resuspended in EBM-
2, and 3×104cells in 300?L medium were seeded on the top of a
Transwell insert (Corning Costar, Lowell, MA) and then placed over
500?L complete EGM-2 to create a positive chemotactic gradient
in a 24-well culture plate. After 24h incubation, cells on the bot-
tom of the insert were fixed in paraformaldehyde and stain with
0.1% crystal violet (Sigma) and visualized by light microscopy. Cells
microscopic fields using an image analyzing software, Image-Pro
2.11. Measurement of cytokine concentration of supernatant
To evaluate the secretion capacities of EPCs, we measured the
concentration of VEGF and SDF-1 in the supernatant of culture
in EBM-2 medium for 3 days, and then the supernatant was har-
vested. Commercially available ELISA kit (Quantikine for VEGF and
SDF-1, R&D Systems, Minneapolis, MN) was used. Concentration
was determined by comparison with a standard curve according to
the manufacturer's instructions. Each experiment was performed
in quadruplicated.
3. Statistical analysis
tion and are reported with a 95% confidence interval, unless
otherwise specified. Comparisons of the continuous normally dis-
tributed variables were performed by paired Student's t-tests
(two-tailed). Categorical variables were compared using Chi2tests
(Fisher's exact test). Analysis were performed using the statistical
and p<0.05 was considered significant.
4. Results
4.1. Clinical characteristics of study subjects
We compared clinical characteristics of ANFH patients and
control subjects in Table S1, Supplementary data. Factors (smok-
ing, alcoholism, hypertension, and hypercholesterolemia) that are
thought to be correlated with the number and function of cir-
culating EPCs were evaluated. And factors (use of glucocorticoid,
thrombophilia) involved in GC-induced ANFH were also deter-
mined. The baseline characteristics were similar except that Total
cholesterol, HDL cholesterol and Triglycerides were significantly
elevated (p<0.001, p=0.048 and p<0.001, respectively) in ANFH
Fig. 1. Cell culture and enumeration of early EPCs and ECFCs colonies from adult
peripheral blood. A. Representative photomicrograph (400×) of an early EPCs
colony characterized by a central cluster of rounded cells surrounded by radiating
thin, flat cells. B. Representative photomicrograph (400×) of ECFCs stained with
crystal violet. C. ECFC colony characterized by cobblestone-like morphology (40×).
Number of early EPCs colonies (D) and number of ECFCs colonies (E) per well in
ANFH were decreased when compared with age- and sex-matched healthy controls
(HC). Results represent the mean values±standard derivation of 33 independent
subjects. *p<0.05 by paired Student's t-test (two-tailed).
4.2. Reduced two types of EPCs colony counts in ANFH
Using a microscope, two types of EPCs colonies were observed
in culture from the mononuclear cells of control groups and
ANFH groups. Early EPCs colonies developed after one week, and
were characterized by a central cluster of round cells surrounded
by radiating thin flat cells (Fig. 1A). ECFCs colonies appeared
after two weeks and varied in size, but all formed a typical
cobblestone monolayer (Fig. 1B, C). Interestingly, we established
that both the number of early EPCs colonies and ECFCs colonies
were decreased in ANFH patients when compared with age-
and sex-matched control subjects (2.42±1.46 colonies/well ver-
sus 4.52±2.00 colonies/well, p<0.05 and 0.62±0.55 colonies/well
versus 1.12±0.82 colonies/well, p<0.05, respectively) (Fig. 1D, E).
Both early EPCs and ECFCs in two groups were stained positively
for DiI-Ac-LDL and FITC-UEA-1 by confocal immunofluorescence
microscope confirming their endothelial phenotype (Fig. 2A–F). In
cific markers of endothelial cells, while the former made up a large
portion of endothelial cell intercellular junctions and the latter was
synthesized exclusively by endothelial cells and functioned in the
maintenance of homeostasis (Fig. 2G–L).
Page 4
C. Chen et al. / Joint Bone Spine 80 (2013) 70–76
Fig. 2. Representative photographs of immunofluorescence staining of early EPCs
and ECFCs. Early EPCs stained by UEA-1 lectin (green) (A), Dil-Ac-LDL (red) (B), and
merged (C) in confocal laser scanning microscope. Bar=10?m. ECFCs stained by
UEA-1 lectin (D), Dil-Ac-LDL (E), and merged (F) by confocal laser scanning micro-
(G, J). Bar=20?m.
4.3. CD133+VEGFR2+cells are not reduced in ANFH
When we analyzed early EPCs on day 7 from ANFH (n=20)
and HC (n=20) by Flow cytometry using antibodies to CD133
and VEGFR2, there was no statistical significant difference in the
percentage of CD133+VEGFR2+ cells in two groups (1.81±0.37%
versus 1.96±0.33%, p=0.092) (Fig. 3A–D).
4.4. Growth kinetics of early EPCs and ECFCs in ANFH
In a comparison of the proliferative kinetics between ANFH and
control groups, we counted the expanded early EPCs and ECFCs
from four different cultures every 3 days. We observed that early
exhibited decreased proliferation in ANFH patients compared to
control subjects (Fig. 4A). PDT also showed a significant difference
in ECFCs growth between groups (6.45±0.40 versus 4.22±0.24,
p<0.05) (Fig. 4B).
4.5. Impaired tube formation of ECFCs in ANFH
To assess the capacity of vasculogenesis, tube formation assay
was performed on both early EPCs and ECFCs using a Matrigel
model. Results showed marked difference. Early EPCs from both
Fig.3. FlowcytometryofCD133+VEGFR2+cellsbyanalysisofculturedearlyEPCson
day 7. A. Position and identification of lymphocyte gate (P1) by light scatter pattern.
(B) Subsequently gates were drawn around the high-expressing distinct population
of CD133+cells, and (C) double-positive events for CD133+and VEGFR2+(CD309)
were determined (Q2-2). The percent of double positive cells were calculated on the
basis of the lymphocyte counts. D. Percentage of CD133+VEGFR2+cells of early EPC
t-test (two-tailed). Data are represented as mean values±standard derivation.
Time (Days)
Number of cells (105)
early EPC-ANFH
early EPC-HC
PDT (days)
Fig. 4. Growth kinetics of early EPCs and ECFCs. A. Representative growth curves of
early EPCs and ECFCs from ANFH and healthy controls (HC) during 30 days culture.
B. Population doubling time (PDT) of ECFCs was significantly decreased in ANFH.
Results represent the average of 4 independent experiments. Data are represented
as mean values±standard derivation. *p<0.05 by paired Student's t-test.
Page 5
C. Chen et al. / Joint Bone Spine 80 (2013) 70–76
and became spindle-shaped but failed to form tube-like structures
(Fig. 5A, B). Of interest, ECFCs organized into capillary structures
with enclosed area successfully, but were impaired in potential to
augment angiogenesis in vitro in ANFH patients (Fig. 5C, D). The
number of closed network units in ANFH was significantly lower
4.6. Impaired migratory function of early EPCs in ANFH
In migration assays, we found that early EPCs from ANFH
patients showed impaired migratory functions (63.8±11.7 versus
152.3±12.4, p<0.001) (Fig. 5E, F, J). However, there were no sig-
nificant differences in migratory functions of ECFCs between two
groups (248.1±19.8 versus 248.9±20.0, p>0.05) (Fig. 5G, H, K).
4.7. Decreased VEGF levels of early EPCs in ANFH
Vascular endothelial growth factor (VEGF) is one of the most
common angiogenic cytokines and stromal cell-derived factor-1
in ANFH compared to control subjects (50.8±7.2pg/ml versus
62.8±10.1pg/ml, p=0.001) (Fig. 6A). But VEGF levels secreted by
ECFCs in two groups showed no difference (32.8±10.5pg/ml ver-
sus 34.0±14.2pg/ml, p=0.554). And SDF-1 levels secreted by both
versus 226.9±27.2pg/ml, p=0.438 and 221.5±36.4pg/ml versus
229.7±39.1pg/ml, p=0.318, respectively) (Fig. 6B).
5. Discussion
One theory of the pathogenesis of GC-induced ANFH suggests
that there is a basic defect of microcirculatory balance in this con-
dition, resulting in chronic regional ischemia and endothelial cell
impairment [3,13,14]. In our previous steroid-induced osteonecro-
sis rabbit models, cytokine-induced mobilization of bone marrow
stem cells increased new vessel formation and thus promote func-
tional bone repair of early stage ANFH [15,16].
In this study, we analyzed the feasibility of isolating both early
EPCs and ECFCs from the peripheral blood of GC-induced ANFH
patients and control subjects, and then we compared the functions
of two types of cells. We reported that both early EPCs and ECFCs
were impaired in number and function in GC-induced ANFH but
they showed different reduced capacity profiles. First, we demon-
strated decreased circulating early EPCs and ECFCs numbers in
GC-induced ANFH than age- and sex-matched control subjects as
evidenced by the appearance of EPCs colonies in culture. In addi-
tion, we found most early EPCs did not proliferate and eventually
died out, which was in agreement with previous reports [17], and
induced ANFH. In tube formation assays, early EPCs failed to form
tubes, which was in line with other studies [11], whereas ECFCs
made tubes successfully but the ability was also impaired in GC-
induced ANFH. When comparing migration capacity, early EPCs
from ANFH patients showed reduced migratory function but ECFCs
seemed not affected. Furthermore, early EPCs secreted more VEGF
than ECFCs, but the secretory function was impaired in GC-induced
ANFH. Based on these results, we interpreted that the decreased
lial dysfunction in GC-induced ANFH and their distinct reduced
capacity profiles might reflect different roles they played. This was
consistent with several previous studies which suggested the cir-
culating EPC number was decreased in some clinical conditions,
such as hypercholesterolemia, hypertension, diabetes mellitus,
Fig. 5. Functions of early EPCs and ECFCs from four ANFH patients and four age- and
sex-matched control subjects. Early EPCs from control subjects (A, ×40) and ANFH
patients (B, ×40) failed to form tube-like structures on Matrigel. ECFCs made tube
formation successfully in control subjects (C, ×40) and in ANFH patients (D, ×40).
Early EPCs from control subjects (E, ×200) and ANFH patients (F, ×200) showed
migratory capacity to cytokines. ECFCs from control subjects (G, ×200) and ANFH
patients (H, ×200) also showed migratory capacity to cytokines. The functional
capacity for tube formation of ECFCs was reduced in ANFH (I). Early EPCs from ANFH
showed no difference in migratory capacity (K). HPF=high power field. Data are
shown as mean values±standard derivation. P values were determined by paired
Student's t-test. *p<0.001.


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McGrath to Step Down from U.K.'s Prudential
LONDON—Prudential PLC said Harvey McGrath plans to step down next year as chairman of the U.K.'s largest insurer by market value.
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Blasts off of 25, leaving a cloud of snow behind.
This morning we decided to wake up at 5:20AM with my friend Michel Varlet to enjoy spotting at CDG. Once arrived I saw this beauty coming in front of us after its landing on runway 09L from Doha i... (more)
Crashed on takeoff on the night of December 20th, no cause found as of the time of writing. Very glad everybody got out, but unfortunately 38 people were injured, with two initially in "serious" c... (more)
Gear doors just beginning to open four miles from landing on R/W 26L.
Tornado GR4 ZG750 has just finished refuelling from ZD953 and is about to depart.
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The first passengers jump out during an emergency evacuation. The Fire Service are dealing with a fire in the left-hand undercarraige.
AMERICAN AIRLINES 757 casts a long shadow on MAHO BEACH.
A shiney, newly delivered Thai aircraft seen moments after completing another super long haul from Bangkok! [Canon 10D]
Departing rwy16R after a fairly quick turnaround. 360mm, 1/20sec, ISO800.