text:
|Publication number
|Publication type
|Application number
|Publication date
|Nov 28, 2000
|Filing date
|Jan 4, 1999
|Priority date
|Jan 5, 1998
|Fee status
|Also published as
|Publication number
|Jean-Marie Parel, Francine Behar
|Original Assignee
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (16), Non-Patent Citations (2), Referenced by (67), Classifications (12), Legal Events (10)
|External Links: USPTO, USPTO Assignment, Espacenet
1. Field of the Invention
The present invention relates to a device for the intraocular transfer of active products by iontophoresis.
2. Discussion of the Background
Iontophoresis is a technique which was proposed in 1747 by Verrati and consists in the administration, in particular of medicaments, into the body through the tissues using an electric field involving a small potential difference. The active electrode, which is in contact with the medicament, is arranged at the site to be treated while a second electrode, intended to close the electric circuit, is placed at another site on the body.
The electric field facilitates the migration of the active products, which are preferably ionized. This technique is commonly used for treating skin diseases, and for this purpose there are a variety of devices available on the market.
Iontophoresis applied to treatment of the eye has been the subject of a number of animal experiments and a few clinical tests, using a variety of devices.
Known devices employ a pad which is impregnated with a solution containing a medicament and is in contact with the surface of the cornea and the sclera. Other devices employ a cup or a pipette. A device employing a cup is, for example, described in American patent U.S. Pat. No. 4,564,016 (David M. Maurice). In this patent, the medicament is administered in quasi-point form through the sclera.
In general, the authors find poor reproducibility in their results, which they attribute either to the existence of differences between the animals which are tested, or to unexplained biological phenomena. Furthermore, some operating techniques involve the use of an active electrode of very small area with a very high current density, which increases the risk of damage caused to the tissues, it being possible for this damage to extend to the presence of burns. This is the case, in particular, with the device described in the aforementioned U.S. Pat. No. 4,564,016, which advocates a current density which is at least 50 mA/cm2 and may even be as much as 2000 mA/cm2.
Some experiments have been carried out with alkaline solutions whose high pH results in local tissue damage. For example, the article by T. T. Lam et al. "Intravitreal Delivery of Ganciclovir in Rabbits by Transscleral Iontophoresis" published in the Journal of Ocular Pharmacology 10(3) p. 571-575 (1994) describes the point administration of a solution whose pH of 10.8 is out of the question except in the laboratory.
The article by F. Behar-Cohen et al., entitled "Iontophoresis of Dexamethasone in the Treatment of Endotoxin-Induced-Uveitis in Rats" in the journal Experimental Eye Research, 1997-65 p. 533-545 (October 1997), relates to transcorneoscleral iontophoresis carried out on rats with a view to the treatment of uveitis, that is to say a condition affecting the uvea. According to this technique, the medicament diffuses essentially through the cornea, then diffuses into the eye media.
In practice, owing to the lack of reproducibility of the experimental results generally obtained and, above all, the description of burns and necrosis to the tissue where the iontophoresis devices are applied, transocular iontophoresis has remained at the laboratory stage and has not yet been accepted as a method of treating patients.
The invention relates to a device for transferring at least one active product into the eyeball by iontophoresis, which makes it possible to carry out ambulatory treatments reproducibly.
The invention thus relates to a device for transferring at least one active product into the human eyeball by iontophoresis, comprising a reservoir of active product, for example of medicament, which can be applied to a patient's eye, at least one active electrode arranged in the reservoir, a passive electrode and a current generator, characterized in that one said active electrode is a surface electrode arranged facing eye tissues lying at the periphery of the cornea. The regions of the eyeball facing the electrode are the corneoscleral limbus, the conjunctiva and/or the sclera and/or the ciliary body and/or the root of the iris and/or the pars plana and/or the anterior vitreous humour and/or the nonfunctional undetachable retina.
Given that the transfer takes place through one or more eye tissues lying at the periphery of the cornea over a wide application area, the reproducibility, transfer uniformity and efficacy are increased. These tissues become impregnated with the medicament (or active product) which may become concentrated there even though the concentrations in the eye media remain low. These concentrations do not reflect the intratissue medicament concentrations. The medicament is thus not eliminated rapidly by the replenishment of the eye liquids (aqueous humour AH and vitreous humour V).
Furthermore, given that the active product is not in contact with the cornea, this avoids the drawbacks of transcorneal iontophoresis and the risk of endothelial lesions, namely the existence after the intervention of sight problems connected either with endothelial lesions or with temporary epithelial lesions or with temporary deposits of active products, which cause blurred vision. The treatment is therefore a genuinely ambulatory one.
Lastly, since the treatment is carried out on a ring peripheral to the cornea, a cylindrical central region of the device can be left fully free, and the practitioner can therefore visually check the centred positioning of the device during the iontophoresis.
All the eye tissues can be treated: conjunctiva, cornea, sclera, iris, crystalline lens, ciliary body, choroidea, retina and optic nerve.
In accordance with the parameters chosen for the current (strength of the current, duration of the treatment), it will be possible for certain tissues to he more specifically targeted.
For an adult (nominal diameter of the cornea: 12 mm), the annular electrode or the electrodes in the form of annular sectors, which is or are made, for example, by electrolytic deposition, may have an internal diameter lying between 12.5 mm and 14 mm and an external diameter lying between 17 mm and 22 mm, which corresponds to an area lying between about 75 mm2 and 250 mm2, and preferably between 17 mm and 20 mm. The maximum diameter is chosen so as not to touch the functional retina. For a child whose eye has not reached adult size, the dimensions need to be adapted in proportion. In other words, and in the general case, the internal diameter di of the annular electrode or of the electrodes is greater than the diameter D of the cornea and less than or equal to 1.2 D, and the external diameter of the annular electrode or of the electrodes is greater than or equal to 1.4 D and less than or equal to 1.8 D, and preferably less than or equal to 1.7 D.
The current generator may be a constant-current generator with rated density less than 10 mA/cm2, which includes a control device which makes it possible to apply the said constant current for a period of time of between 30 seconds and 10 minutes, and more particularly between 1 minute and 10 minutes.
The density of the constant current is advantageously adjustable between 0.1 mA/cm2 and 5 mA/cm2, for example between 0.2 mA/cm2 and 5 mA/cm2, or alternatively between 0.8 mA/cm2 and 5 mA/cm2.
The current may be applied progressively, for example during the initial seconds, which avoids the patient's reflex muscular reactions.
The current is advantageously delivered at a voltage lying between 1.5 V and 9 V, and preferably between 2 V and 8 V.
The concentration of the active product is arbitrary. It is in particular less than or equal to the saturation concentration of the active product in water. It is preferably greater than or equal to a threshold concentration beyond which accummulation in some of the eye tissues followed by release to other tissues takes place.
The active product arranged in the reservoir has a pH which may advantageously lie between 6 and 8, and preferably between 7 and 7.6. It will be noted that, since the active product is not in contact with the cornea, the chosen pH may be substantially higher than indicated above, because the conjunctiva and the sclera are less susceptible both in terms of sensitivity and in terms of lesions to slightly acidic or basic pH values. The cornea must remain transparent. Any modification to the physiological conditions risks impairing its tissue characteristics, and therefore its transparency. The conjunctiva is a mucous membrane, and the sclera is a conjunctive tissue. These are two very resistant tissues whose function is not, in the application region of the treatment, directly involved in the transmission of photons to the retina. They are connective tissues.
The device preferably has a pumping device for circulating a solution of active product, for example a medicinal solution, through the reservoir. This makes it possible, on the one hand, to eliminate the gas bubbles which may be formed during the iontophoresis and, on the other hand, to keep the composition and the pH of the solution substantially constant throughout the treatment, and therefore to improve its reproducibility.
According to a first embodiment, the device has an annular reservoir having an annular electrode, which may define the bottom of the reservoir.
According to a second embodiment, the device has an annular reservoir having a plurality of compartments in the form of annular sectors and electrodes in the form of an annular sector, which may define the bottom of the annular sectors.
According to a third embodiment, the device consists of a corneal lens which is provided with a surface electrode on its internal face and in which a gel containing at least one active product is arranged, or which itself has a spongy structure and contains the active product (for example a cross-linked matrix).
Preferably, on an external face, the device includes a passive electrode which comes into contact with the patient's partially closed eyelid, which holds the device in place throughout the treatment. This also provides the advantage of electrical contact which is improved because it is in an aqueous environment.
Other characteristics and advantages of the invention will become more clearly apparent on reading the following description, given by way of non-limiting example in conjunction with the appended drawings, in which
FIG. 1 represents a section of an example of a device described in the aforementioned article by F. Behar-Cohen et al.
FIGS. 2a to 2c respectively represent a section, a plan view and a perspective view of an example of a device according to the invention
FIGS. 3a, 3b and 3c respectively represent a section, a plan view and a perspective view of a device according to the invention for administering three active products, for example three medicaments
FIG. 4 represents a section of a variant of the device according to FIGS. 3a to 3c
FIGS. 5a to 5b represent a device according to the invention, in the form of a meniscus intended for administering three active products, for example three medicaments, in gel form
FIGS. 6a to 6c respectively represent a perspective view, a section and a partial section of a device of the meniscus type according to the invention
FIG. 7 represents a preferred embodiment of a device intended for administering a plurality of active products, for example medicaments
FIGS. 8a and 8b are results of a test carried out on rabbits, with the concentration in μg/g of dry tissue and in μg/ml for the eye media on the ordinate, and the time in hours on the abscissa
FIG. 9 represents a device according to the invention as fitted on an eye to be treated
and FIG. 10 represents a plan view of a preferred alternative embodiment of the invention.
FIG. 1 schematically represents the iontophoresis system employed in the context of the aforementioned article by F. Behar-Cohen et al. It includes a polymethyl methacrylate (PMMA) reservoir 8 defined by a cylindrical wall 2 and a bottom 3 in proximity to which a circular platinum electrode 4 is arranged. The reservoir 8, with a diameter of 6 mm, covers the cornea, the limbus and the first millimeter of the sclera of a rat. A feed tube 5 makes it possible to fill the reservoir 8 with a solution metered in a proportion of 1 mg of dexamethasone per ml of a pH 7 sterile saline solution, and a discharge tube 6 makes it possible to extract the air bubbles which are formed during the iontophoresis. Continuous circulation of the solution makes it possible to keep the pH of the solution in contact with the cornea constant.
A return electrode 7 is placed in contact with one of the rat's paws.
The system also includes a voltage source VS, and a current regulator I. A device IMM for measuring impedance makes it possible to detect any electrical discontinuity and trigger an alarm A. The quantity of charge delivered is displayed on the generator at the end of treatment and makes it possible to ensure reproducibility of the administered treatment.
The experiments were carried out with a current of 400 μA for 4 minutes, i.e. a density of 1.2 mA/cm2 and a total charge of 0.12 coulomb i.e. 0.4 C/cm2.
The device according to the invention, an embodiment of which is represented in FIGS. 2a and 2b, makes it possible to transfer active product, for example a medicament, essentially through at least one eye tissue.
The active electrode is advantageously placed at a distance a from the surface of the patient's eye which is sufficient to avoid a short-circuit, or to avoid it coming accidentally into contact with the eye. This distance a is preferably at least equal to 4 mm.
The device may be made of PMMA or preferably silicone, for example PDMS with a Shore hardness of 20, for a better seal at the eye. Another biocompatible material which may be used is polyurethane, in particular a polyurethane which is hydrophilic in order to improve adhesion and the elimination of bubbles.
The device 10 has an annular wall 17 and two cylindrical side walls, an inner one 19 and an outer one 18, defining an annular region 15 which forms a reservoir for an active solution, for example a medicinal solution, to be administered by iontophoresis at the periphery of the cornea C of an eye 20 to be treated. The end of the wall 18 adjacent to the wall 17 rests through a frustoconical edge 16 on the sclera S, and the end of the wall 19 adjacent to the wall 17 rests through a frustoconical zone 19' on the perimeter of the cornea C so that only a region which is peripheral to the cornea C and has one or more eye tissues is exposed to the medicinal solution contained by the reservoir 15. An annular active electrode 11 borders the wall 17. Two conductive connections 11' and 12' make it possible to electrically connect the active electrode 11 and the return electrode 12, which is advantageously arranged on the external face of a ring 16, so that the patient's partially closed eyelid can come into contact with the electrode 12 and thus close the circuit.
Alternately, the return electrode may be separate and arranged on the patient's forehead, close to the eye to be treated. In this case as well, the patient's eyelid may rest on the ring 16 in order to hold the device in place.
Openings 13 and 14 formed in the wall 17 make it possible to fill the reservoir 15 and/or circulate the medicinal solution.
The plane annular electrode 11 preferably covers the entire surface of the wall 17 which defines the bottom of the annular reservoir 15. Only partial coverage is admittedly envisageable, but can only unfavourably influence the efficacy of the treatment. Whatever the case, the reservoir 15 must not cover the region of the cornea C.
The device represented in FIGS. 3a, 3b and 3c makes it possible to administer a plurality of active products, for example medicaments, here three of them, in liquid or gel form, which are each arranged in one of three cavities in the form of an annular sector 45, 46 and 47 each of which is provided with a respective active electrode 41, 42 and 43. The device includes an annular wall 27, and two cylindrical walls, an inner one 49 and an outer one 48, and the sectors are defined by separating walls 40. It is placed on the patient's eye in the same way as the device represented in FIGS. 2a and 2b. Conductive connections 41', 42' and 43' pass through the wall 27 to electrically supply the active electrodes 41, 42 and 43.
The device represented in FIG. 4 is distinguished by the presence of tubes for circulating liquid which are present for each cavity 45, 46 and 47. The drawing shows the tubes 84, 85 and 86, 87 corresponding to the cavities 45 and 46.
The device represented in FIGS. 5a and 5b is a meniscus in the form of a ring. It has three reservoirs 55, 56 and 57 each of which is intended to hold a medicinal gel or a porous material, such as a sponge, impregnated with an active product, for example a medicament. A respective active electrode 51, 52 and 53 is associated with each reservoir. The reservoirs 55 in the form of sectors are defined by separating walls The device represented in FIGS. 6a to 6c is a flat meniscus in ring form made of a material which may be that of a corneal lens. The cylindrical central space 63 is left free and, as with the other embodiments, allows a visual check of the centred positioning of the device. An electrode 61, for example formed by electrolytic deposition, covers the slightly concave internal face 63 of the bottom of the annular cavity 62. A return electrode 64, for example formed by electrolytic deposition, covers the perimeter of the convex external face 66 of the bottom of the annular cavity 62, so as to allow return electrical contact through at least one of the patient's closed eyelids 22, 24. The routing of the electrical contact wires 67, 68 is arranged in such a way as to allow them to exit between the eyelids.
The device according to the invention is generally suitable for simple molecules or for molecular assemblies used as an active product (for example medicaments and/or peptides and/or proteins and/or gene fragments) whose molecular mass is less than 100 kilodaltons.
Operation is carried out with a direct current which is constant and regulated with a current density that does not exceed 10 mA/cm2. This current density can advantageously be adjusted between 0.1 mA/cm2 and 5 mA/cm2, and for example between 0.2 mA/cm2 and 5 mA/cm2. The preferred value range lies between 0.8 mA/cm2 and 5 mA/cm2. The treatment time may lie between 30 seconds and 10 minutes. It may in particular lie between 1 minute and 10 minutes.
For a human being, the diameter of the cornea (with limbus) is about 12 to 13 mm with an ora serrata about 18 mm in diameter.
By way of example, for treating adults, use may be made of an annular electrode or a plurality of electrodes in the form of ring sectors having an internal diameter lying between 12.5 and 14 mm and an external diameter lying between 17 mm and 22 mm, which corresponds to an area lying between 75 mm2 and 250 mm2, and preferably lying between 17 mm and 20 mm. The current may, in this case, for example be 400 μA and be applied for 4 minutes.
It will be noted that the arrangement of the active electrodes, namely of the surface electrodes arranged facing the region(s) to be treated, makes it possible to associate with a constant current a current density which is itself constant and uniform over the entire area of the region to be treated.
This presents several advantages.
Firstly, it prevents the current density from being able to locally reach high values in certain zones of the region to be treated, and therefore giving rise to undesirable side effects.
Furthermore, the uniformity of the current density in the region to be treated has the effect that the penetration of the active product or products, for example of the medicaments, is also uniform over the region to be treated.
Whatever the case, the electrode does not face the functional retina.
In the scope of the present invention, at least one active product, for example a medicament, is administered via the tissues which allow the better penetration of the active product, in the anterior and posterior segment: the corneoscleral limbus, the conjunctiva, the sclera, the ciliary body, the root of the iris, the pars plana, the anterior vitreous humour, the choroidea and the nonfunctional undetachable retina.
The absence of contact with the cornea avoids any risk of physical and chemical lesion and, in particular, temporary or permanent eye problems following the treatment, and it also makes it possible to leave free a central space 23 allowing the practitioner to check the positioning of the instrument throughout the treatment.
Furthermore, it is found that beyond a certain concentration of active product, which varies depending on the nature of the active product, the active product accummulates in certain tissues of the eye 'sustentacular space, sclera, suprachoroid space and, to a lesser extent, iris I and ciliary body CC) before being progressively released to other tissues (choroid CH, retina RET), thus increasing the action time (half-life before elimination of the active product).
This phenomenon is illustrated by the appended curves (FIGS. 8a and 8b) obtained on the basis of experiments carried out on rabbits with methylprednisolone hemisuccinate (150 mg/ml, 2 mA). With a 62.5 mg/ml strength solution, the release effect is not observed. The concentration threshold which allows release is about 100 mg/ml.
The device according to the invention may be axisymmetric, but it is preferable for it to be substantially oval in order to accommodate, on the one hand, the presence of the eyelids and, on the other hand, the slightly oval profile of the cornea.
The device represented in FIG. 7 has a cavity with an elliptical external profile of 20 mm focal axis parallel to the closure line of the eyelids, and of 18 mm minor axis.
An elliptical internal profile of the treatment cavity may, for example, have a major axis which is parallel to the closure line of the eyelids and is equal to 13.5 mm, and a minor axis which is perpendicular to this line and is equal to 12.5 mm.
The device represented in FIG. 7 has four cavities 71 to 74 each of which has an active electrode 75 to 78 supplied by an individual electronic circuit 79 to 82 which is similar to the one represented in FIG. 1 and which is integrated in the device. The electronic circuits are supplied by a battery 84 constituting the voltage generator VS, and include a constant-current source I regulated to a chosen value, and a timer T allowing the desired treatment time to be set. Alternatively, all the circuits may be arranged on a single integrated circuit, or alternatively the functions may be distributed over several internal circuits connected by a bus 85.
It will be noted that the reservoir may be oval or, alternatively, have an elongate shape, for example an elliptical shape.
The reservoir and/or the active electrode may be annular.
It is also within the scope of the present invention for the reservoir to have an internal diameter di with D<di≦1.2 D, D denoting the diameter of the cornea, and an external diameter de with 1.4 D≦de≦1.8 D, and preferably 1.4 D≦de≦1.7 D.
The device may be held in place using a suction device producing a vacuum lying between 35 mm Hg and 100 mm HG, and preferably of the order of 50 mm Hg. This vacuum may in particular be generated using a preferably transparent diaphragm 95 (FIG. 9) which closes off the external face of the central space 23, which makes it possible to create a vacuum therein by suction. This vacuum may also be created by the practitioner if he presses on the diaphragm 95 to flush the air from the central space, which will cause a said vacuum after release. Since the depressurizing diaphragm 95 is transparent, the practitioner can check the positioning of the instrument during the treatment, by virtue of the central space 23.
The active product may be injected through a syringe or, alternatively, from a container of active product adjacent to the device.
When the device is made of a flexible material, which is favourable in terms of fitting and sealing, the external 18 and internal 19 cylindrical walls will tend to come into contact with one another.
In order to overcome this, fins 90 are provided, for example plane radial fins which preferably extend from one of the cylindrical walls (18 or 19) while remaining spaced apart from the other wall (19 or 18) when the device is inactive. In order to facilitate the discharge of air bubbles, the active solution is injected into the reservoir 15 through an inlet 13' (see FIG. 10) lying in the lower part ("6 o'clock position") of the device when placed on the eye of a patient whose head is tilted backwards, and an opening 14' for discharging the bubbles is provided in the upper part ("12 o'clock position"). In order to assist in discharge of the bubbles, the fins 90, which in the example which is represented extend from the wall 18, are curved and are convex in the direction of the inlet opening 13'.
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|Jul 18, 2007
|Aciont Inc.
|Methods and devices for sustained in-vivo release of an active agent
|Oct 24, 2006
|Jul 9, 2008
|Aciont Inc.
|Intraocular iontophoretic device and associated methods
|Nov 22, 2004
|Apr 29, 2009
|Othera Holding, Inc.
|Use of at least one hydroxylamine compound for the treatment of eye disease
|Apr 18, 2006
|Dec 29, 2010
|INSERM (Institut National de la Sant� et de la Recherche M�dicale)
|Devices for delivering a biologically active agent to the ocular sphere of a subject
|Feb 15, 2008
|Jul 31, 2013
|Colby Pharmaceutical Company
|Hydroxylamine compounds and methods of their use
|Apr 29, 2005
|Oct 2, 2013
|Eyegate Pharma SA
|Irritation-reducing ocular iontophoretic device
|Apr 17, 2002
|Oct 24, 2002
|Francine Behar-Cohen
|Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis
|Oct 11, 2002
|Apr 17, 2003
|Optis France S A
|Device for delivering medicines by transpalpebral electrophoresis
|Oct 11, 2002
|May 30, 2003
|Behar Francine
|Device for medicine delivery by intraocular iontophoresis or electroporation
|Jan 3, 2006
|Jul 13, 2006
|Eyegate Pharma Sa
|Ocular iontophoresis device for delivering sirna and aptamers
|Apr 18, 2006
|Nov 23, 2006
|Inst Nat Sante Rech Med
|Improved methods and devices for delivering a therapeutic product to the ocular sphere of a subject
|Nov 29, 2006
|Sep 7, 2007
|Eyegate Pharma S A
|Ocular iontophoresis device
|Jun 24, 2011
|Dec 29, 2011
|The U.S.A., As Represented By The Secretary, Department Of Health And Human Services
|Methods of treatment using sterculic acid
|Jan 12, 2011
|Jul 19, 2012
|Sooft Italia Spa
|Device and method for corneal delivery of riboflavin by iontophoresis for the treatment of keratoconus
|May 24, 2012
|Nov 29, 2012
|Pepose Jay
|Device and method for administering eye medications
|U.S. Classification
|604/20, 604/521
|International Classification
|Cooperative Classification
|European Classification
|Mar 29, 1999
Owner name: OPTISINVEST, NETHERLANDS ANTILLES
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:PAREL, JEAN-MARIE;BEHAR, FRANCINE;REEL/FRAME:009862/0756
Effective date: 19990113
|Mar 4, 2003
|Request for reexamination filed
Effective date: 20030128
|Apr 16, 2004
|May 5, 2004
|Fee payment
Year of fee payment: 4
|Nov 15, 2004
|Jul 26, 2005
|Reexamination certificate first reexamination
Free format text: THE PATENTABILITY OF CLAIMS 1-29 IS CONFIRMED. CLAIM 30 IS CANCELLED.
|Oct 31, 2006
Owner name: EYEGATE PHARMA S.A.,FRANCE
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Effective date: 20050629
|Jan 3, 2008
Owner name: EYEGATE PHARMA S.A.S., FRANCE
Free format text: CHANGE OF LEGAL ENTITY;ASSIGNOR:EYEGATE PHARMA S.A.;REEL/FRAME:020312/0374
Effective date: 20060905
Owner name: EYEGATE PHARMA S.A.S.,FRANCE
Free format text: CHANGE OF LEGAL ENTITY;ASSIGNOR:EYEGATE PHARMA S.A.;REEL/FRAME:020312/0374
Effective date: 20060905
|May 28, 2008
|Fee payment
Year of fee payment: 8
|May 24, 2012
|Fee payment
Year of fee payment: 12


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Japan, Korea, and China face off in a new League of Legends Asian sub-league this December
A new Asian sub-league has been announced for League of Legends, which will include teams from Japan, Korea, China, and Taiwan.
A new Asian sub-league has been announced for League of Legends, which will include teams from Japan, Korea, China, and Taiwan.
Rumors have spread that a Chinese League of Legends team will be heading to Korea, but unfortunately it's false.
League of Legends is still the king in this month's top 10 list of the most popular games in Korea.
Black Squad looks like Crossfire 2.0, and the more you see it in action, the more there is to like.
A complex nexus of app discovery, engagement, and monetization - those are the main challenges facing startups and smaller app developers.
The best of Asian mobile gaming from August 1 to August 8, 2014. Knock yourselves out!
It is a battle for honor and third place. However T1 S also fights for the future of its sister teams and its spot at the World Championship. Check in to see, i...
Ben "Merlini" Wu, a Dota player widely known for his skill with Zeus, will temporarily join Team Zephyr in Korea.
Asia's first region-wide FIFA Online 3 tournament has been announced! Sponsored by FIFA Online 3 developer Spearhead, the three-day long invitational will take ...
Want to know why Korean Dota 2 teams are bad? Because they only have high APM, says China.
Is it a plane? Is it a bird? No! It's Kakao! One of the most representative figures in the Korean League of Legends scene. His evil plot to dominate Season 4 Wo...
The Tree of Savior hype train has just been derailed, with the MMORPG's developer IMC Games announcing a lack of a Korean publisher.
The editors at Duowan rank the top twenty LOL teams in the world right now. Do you agree with their picks?
Pearl Abyss has confirmed that Daum will indeed be publishing the gorgeous Korean MMORPG Black Desert in North America and Europe.
While Uber has hit its toughest regulatory road block yet in Seoul, last-mile delivery service Naldo pushes forward with its plan to upend South Korea's logisti...
Many people with disabilities can still compete at the highest level in eSports, and to help showcase this, the International eSports Federation will be hosting...
China may have won $5 million from The International 2014 (TI4), but it's still not the top highest-earning eSports country in Asia.
Anti-Korean sentiment is on the rise in China as netizens make some very nasty remarks against World Elite.
Korean gamers will soon be able to take their love of MOBA games out for a spin on the high seas!
KakaoTalk now has 520 social games, along with 20 million monthly active gamers.

subset: commoncrawl


text: More from SI Report: Dodgers release pitcher Freddy Garcia Report: Dodgers release pitcher Freddy Garcia Marshawn Lynch sports gold cleats for Super Bowl Marshawn Lynch sports gold cleats for Super Bowl Louisville vs. FIU: Game time, live stream, TV coverage Louisville vs. FIU: Game time, live stream, TV coverage Pittsburgh-area high school football player dies after... Pittsburgh-area high school football player dies after... Close Tweet0 Share0 Comment0 Share0 Share0 Stumble It0 Print0 More SI Wire Report: Astros trade Brett Myers to Chicago White Sox by Brett LoGiurato Email Posted: Sat Jul. 21, 2012 The Houston Astros traded closer Brett Myers to the Chicago White Sox on Saturday, Fox Sports' Ken Rosenthal reported on Twitter.Source: #WhiteSox acquire Brett Myers from #Astros.— Ken Rosenthal (@Ken_Rosenthal) July 21, 2012The Houston Chronicle's Zachary Levine reported that the Astros received three players from the White Sox in exchange for Myers.Astros get White Sox RHP Matt Heidenreich, LHP Blair Walters and a player to be named later in Myers deal— Zachary Levine (@zacharylevine) July 21, 2012The 31-year-old Myers is 0-4 with a 3.52 ERA in 35 appearances this season. He has converted 19 of 21 save opportunities and has struck out 20 in 30 2/3 innings.Myers is in the final year of his contract, but he has a vesting option that could guarantee his $10 million option next season if he appears in a certain amount of games. Rosenthal reported in June that the best estimate would be between 40 and 50 games, because the Astros reworked his contract when they converted him from a starter to closer before the season.The move makes sense for the White Sox, who have the third-worst bullpen ERA in the American League. Rookie Addison Reed, the team's closer for most of the season, has a 4.24 ERA and has converted 15 of 18 save opportunities. The White Sox currently have 1/2 game lead on the Detroit Tigers in the AL Central. Promoted Stories Comments


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The Commission on Dental Accreditation (CODA) is calling for nominations to fill vacancies for public members of its review committees. Public nominees should not have a formal or informal connection to dentistry, but they should have an interest in or knowledge of health-related accreditation issues.
Here are five great reasons to attend the 2012 ADEA Annual Session & Exhibition in Orlando, Florida.
Since 1999, more than 200 fellows from predoctoral, allied, and advanced dental education have participated in the ADEA Leadership Institute. Institute fellows hold positions ranging from department chairs to program directors to deans of dental schools. Throughout the year-long program, participants explore leadership styles, emotional intelligence, organizational theory, team building, stress management, work-life balance, strategies for leading change, and giving and receiving feedback.
The ADEAGies Foundation is accepting nominations through November 1, 2011 for the 2012 William J. Gies Awards for Vision, Innovation, and Achievement. The Gies Awards, named after dental education pioneer William J. Gies, Ph.D., recognize exceptional contributions to and support of oral health and dental education around the world.
Many educators, administrators, and students in the dental education community have outstanding achievements or demonstrate exceptional commitment—they simply have not yet been recognized. How will that happen? As the saying goes, you can't win if you don't play. Academic dentistry as a whole won't gain the broader benefits of your work if no one knows about it. So now is the time to nominate for recognition through ADEA's programs. Self nominations are encouraged.
Nominations will be accepted through November 1, 2011, for the 2012 William J. Gies Awards for Vision, Innovation, and Achievement. Presented by the ADEAGies Foundation, the Gies Awards recognize exceptional contributions to and support of oral health and dental education around the world.
Opportunities for student leadership are not restricted to the dental school campus or local community. Students looking for ways to make an impact on public policy don't have to wait until after graduation. Advocacy begins with a desire to help others through activities that can influence public policy and be accomplished on the local, state, and national levels of government.
This is it: Registration closes September 12, 2011, for the ADEA BFACA Mid Year Meeting, and September 16, 2011 for the ADEA Fall 2011 Meetings.
The Crowne Plaza Riverwalk in San Antonio, Texas, will host the ADEA Fall 2011 Meetings, including the Fourth ADEA Summit on Advanced Dental Education, from October 20-22, 2011. This year's opening plenary on Thursday afternoon will be given by Dr. Milton Chen, Senior Fellow and Executive Director Emeritus of The George Lucas Edcuational Foundation (GLEF), promising a lively question-and-answer session on modern innovations in education.
The 2011 ADEA BFACA Mid-Year Meeting will be held at the Kabuki Hotel in San Francisco, California from October 13-16. This meeting is open to all of those interested in Business, Financial, and Clinic Administration (BFACA). Attendees will have the opportunity to hear from exciting keynote speakers, network with other professionals, and tour a local dental school (preregistration is required).


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Connect With Me
Upcoming Events
Unlocking the Keystone State: Key Resources and Repositories for Pennsylvania ResearchNovember 18 @ 7:00 pm - 8:30 pm
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Pennsylvania Research WorkshopMarch 5, 2016 @ 1:00 pm - 4:00 pm
Analysis and Correlation: Two Keys to ConclusionsMarch 7, 2016 @ 7:00 pm - 8:00 pm
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Tag Archives: George Washington
6 Degrees Of Separation (Genealogy-Style): George Washington
So here was my random, cool thought for the genealogical week: Using people from your genealogical data, how far separated are you from famous figures in American history? Let's start with George Washington…since he's the one that got me wondering. … Continue reading
Posted in Fun!, Thoughts and Musings Tagged 6 Degrees Of Seperation, A.A. Staats, Family Findings, George Washington, Rufus Putnam, Staats, Walter Staats 3 Comments


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Safety First
Season 1 - Ep. 11
The guys have to give CPR lessons.
Up Next
Impractical Jokers
Season 1 - Ep. 11
Full Episodes
Safety First
The guys have to give CPR lessons.
More From Impractical Jokers
- Impractical Jokers Impractical Jokers Webchat The <i>Impractical Jokers</i> return with new episodes and a special web chat with their fans.
- Impractical Jokers DELETED SCENE: Checking For Guns Q is the ultimate in club security.
- Impractical Jokers James Murray: Off The Couch Some of Murr's funniest moments.
- Impractical Jokers Impractical Jokers Returns They're unwanted, uninvited and uncomfortable and they're back.
- Impractical Jokers DELETED SCENE: Big Dork Q has fun with a permanent marker!
- Impractical Jokers DELETED SCENE: Do Not Tip This Man Murr gets excited when you give him tips.
- Impractical Jokers DELETED SCENE: Turkeypiece Theatre Bravo! Q Bravo!
- Impractical Jokers DELETED SCENE: Survey Stupidity An odd question pops-up during a survey. Will Joe go through with asking it?
- Impractical Jokers DELETED SCENE: Sal Central Station Sal conducts a man on the street interview in Grand Central Station.
- Impractical Jokers Horrorscope Sal or Murr attempt to tell these women what their sign really means.
Show Clips
- Impractical Jokers Lost in Translation Murr asks strangers to translate a Spanish text and defends leaving his grandpa behind on Mount Kilimanjaro.
- Impractical Jokers Pizza Thief Q sneaks bites from customers' slices at a pizzeria.
- Impractical Jokers Tasteless Taste Test Sal conducts a food survey with a series of uncomfortable questions.
- Impractical Jokers Watch My Kid Murr must convince a group of strangers to watch his son while he "makes it rain on dem ho's."
- Impractical Jokers Sal in Hi-Def Glory The guys admire an unflattering blown-up photo of Sal brought by an audience member.
- Impractical Jokers Challenges You'll Never See on TV The guys give an inside look at the many questionable Jokers challenges that didn't make it to air.
- Impractical Jokers Live Punishment After-Show The guys discuss what was going through their heads during their death-defying act.
- Impractical Jokers Live Punishment Pre-Show Look back at the funniest, most cringe-worthy moments from the show and sit down with a few familiar faces.
- Impractical Jokers Greeting Card Dares Q chats about his ugly children and gets low with a stranger at a greeting card store.
- Impractical Jokers Unreal Estate Q and Joe teach an introductory real estate course to a group of hopeful realtors.


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2015 ASQ:SE-2™ Training of Trainers Institute
October 27–28 in Chicago: Only a few seats remain!
Online registration is closedEmail us for remaining availability
Learn everything you need to know to instruct your colleagues in using the NEW Ages & Stages Questionnaires®: Social-Emotional, Second Edition (ASQ:SE-2™) to screen infants and young children for social-emotional delays.
This thorough seminar shows you how to
- implement ASQ:SE-2 effectively
- score questionnaires and interpret results
- discuss results sensitively with families
- understand the referral process
- work with families from diverse cultural backgrounds
- teach others within your organization how to successfully use ASQ:SE-2
While at the Institute, you'll receive instruction from an ASQ expert, practice forms, case studies, and a binder with handouts for conducting trainings within your organization. Upon your successful completion of the Institute, a certificate of attendance and a USB flash drive of training materials will be sent by mail.
Who should attend
The 2015 Institute is designed for intermediate to advanced ASQ users who already oversee ASQ implementation and ASQ training within their organization; participants will leave the Institute prepared to instruct colleagues on ASQ:SE-2. However, new ASQ users also may find the Institute beneficial to their understanding and implementation of ASQ:SE-2. All participants will receive valuable information to advance their skill level and knowledge of the tools.
Meet your presenter
Elizabeth Twombly, Ph.D., has been involved in research, outreach, and training projects related to ASQ for more than 14 years. Most recently she has worked as a senior research assistant in the development of ASQ:SE-2 and as a co-author of the Ages & Stages Learning Activities. Ms. Twombly trains early childhood professionals nationwide on the use of ASQ-3 and ASQ:SE-2.
2015 ASQ:SE-2 Fall Institute FAQs
What you need to know about registration
Registration fills quickly! Please note that we have a specific number of seats available for our special edition ASQ-SE-2 Training of Trainers Institute. The demand is high and seating is very limited and will fill quickly. We cannot guarantee that seating will be available through the registration cutoff date of October 12, 2015. Registration may be closed prior to the cutoff date if we've reached maximum capacity.
SPECIAL NOTE: The October 2015 ASQ:SE-2 Training Institute will focus solely on the new edition of ASQ:SE-2, and will not address ASQ-3.
Where will the training take place?
Office Evolution Training Room
8745 W. Higgins Road
Chicago, Illinois 60631
Where should I park when attending the training?
Office Evolution has complimentary parking available at their location as long as you enter into the garage marked Visitor Parking Entrance. Guests should enter via the unnamed road prior to the entrance for the Marriott O'Hare and the AMA Conference Center. Drive beyond the parking garage and parking ramp on the right, and continue to follow the signage for Visitor Parking in the two-level parking garage. From the Visitor Parking, take stairs down to enter the Office Evolution Training Room at 8745 Higgins Road.
What is the closest airport in Chicago?
O'Hare International Airport (ORD) is the closest airport and conveniently located 15 minutes from the Office Evolution Training Room and Aloft Chicago O'Hare Airport Hotel.
Midway Airport (MDW) also serves the Chicago area. Midway is 35 to 45 minutes from the Office Evolution Training Room and Aloft Chicago O'Hare Airport Hotel.
Transportation options
From O'Hare:
The Aloft Chicago O'Hare Airport Hotel runs a complimentary shuttle from the lobby to all terminals within the airport. Cab service from the airport to the Aloft Chicago O'Hare Airport Hotel will cost approximately $18.
From Midway:
Cab service from the airport to the Aloft Chicago O'Hare Airport Hotel will cost approximately $35. Omega Airport Shuttle provides service between airports – call 888-284-3826 for rates and reservations.
Parking is available at the Aloft Chicago O'Hare Airport Hotel for a discounted fee of $23.00 per night.
Our host hotel, The Aloft Chicago O'Hare Airport Hotel, offers complimentary shuttle service to/from O'Hare Airport for guests who reserve rooms from our discounted hotel room block. Additionally, for guests who stay at the Aloft Chicago O'Hare Airport Hotel, complimentary shuttle service to the Office Evolution Training Room will be provided from the hotel lobby.
How do I get from the airport to the training location if I rent a car?
Rental car companies will provide directions and often a map of the local area. For more specific directions to the training location, visit mapquest.com and use 8745 W. Higgins Road, Chicago, IL 60631 as your destination.
Where should I stay since the training is not taking place in a hotel?
Aloft Chicago O'Hare Airport Hotel
9700 Balmoral Avenue
Rosemont, IL 60018
Hotel number: 847-671-4444
Reservations number: 866-716-8143
A limited number of guest rooms have been reserved at the Aloft Chicago O'Hare Airport Hotel for a discounted rate of $169.00 per night plus applicable taxes, currently 13%. Please call 866-716-8143 to make your overnight reservations or make reservations online.
How do I get from the airport to the Aloft Chicago O'Hare Hotel if I rent a car?
Rental car companies will provide directions and often a map of the local area. For more specific directions to the hotel, contact the hotel concierge or visit mapquest.com.
Please use this address for the Aloft Chicago O'Hare Hotel: 9700 Balmoral Avenue, Rosemont, IL 60018.
Do I need to pay to park at the hotel?
Self-parking is available for an additional fee and is subject to applicable tax. Please contact the hotel to verify the fees.
At time of publication, parking rates for self-parking are $23.00 per night plus applicable taxes with in-and-out privileges. Rates are subject to change at the hotel's discretion.
What time can I check-in at the hotel?
Check-in is 3:00 p.m. If you arrive early and your hotel room is not available, you may check your luggage and enjoy the Chicagoland area until check-in time.
When do I need to check-out of the hotel?
Check-out is 12:00 noon. Unless you are staying an additional night, you will need to check-out on Wednesday, October 28 by 12:00 noon. Luggage storage may be available at the hotel for a nominal fee.
Are hotel accommodations included in the registration fee?
No, for the Institute, you will need to make your own hotel reservations.
A limited number of rooms have been reserved at the Aloft Chicago O'Hare Airport Hotel for a discounted rate of $169 per night for single & double occupancy. Rooms are on a first-come, first reserved basis. The hotel may not be able to extend the discounted rate beyond the room block or the cutoff date. To qualify for these rates, please make your reservations no later than October 12, 2015, and specify the code ASQ:SE-2 Training of Trainers. You can reach the hotel by calling 866-716-8143 or book online.
Though there are many hotels in the Chicago/O'Hare Airport area, we have negotiated a deeply discounted room rate at the Aloft Chicago O'Hare Airport Hotel. If possible, please take advantage of this tremendous discounted opportunity and stay in a great hotel connected to 8 amazing restaurants, entertainment options, and attractions!
The hotel offers complimentary wireless internet throughout the entire hotel and a discounted parking rate of $23 per night plus applicable taxes.
Are hotel accommodations for single or double occupancy?
The discounted rates are for single or double occupancy (1 or 2 people) and do not include applicable state and local taxes, surcharges, parking, or other incidental fees. An additional fee may be added for the third and fourth person staying in a room.
Will I need to pay a deposit on the hotel room or will my credit card be sufficient?
No, the hotel does not require a deposit. However, when you make a reservation they will ask for a credit card to guarantee the reservation.
Do I need to bring any ASQ materials to the Institute? / What products are required for the training?
Yes, you will need to bring the following:
The ASQ:SE-2 User's Guide (Brookes Publishing Stock #79581, $50.00)
Participants must bring the ASQ:SE-2 User's Guide to the Institute. Participants from the same program may share Guides. Please purchase your Guides from Brookes Publishing and bring to the Institute. A pre-Institute discount code for 20% off will be sent by email when you receive your registration confirmation. Order by phone at 1-800-638-3775 or online at www.brookespublishing.com. For U.S. customers, orders must be received by 4:00 p.m. EST on September 30, 2015; otherwise RUSH shipping charges may apply. For outside the U.S., including Canada, orders must be received by 4:00 p.m. EST on September 1, 2015 (international RUSH shipping may be required).
Do I need to bring the ASQ:SE-2 Questionnaires or Starter Kits to the Institute?
No, you only need to bring the ASQ:SE-2 User's Guide to the Institute.
How can I purchase the required User's Guides?
You may purchase your required materials from Brookes Publishing Co. by either going online to www.brookespublishing.com or by calling us at 1-800-638-3775. Institute attendees receive a 20% pre-Institute discount code to be used on all ASQ-3 and ASQ:SE-2 products (except ASQ Online); the discount code will be provided in the confirmation letter within 7 business days. See www.agesandstages.com for information on the complete ASQ product line.
What are the hours of the training?
The Institute hours are 8:30 a.m. to 4:30 p.m. on Tuesday, October 27, 2015 and Wednesday, October 28, 2015. Schedule is subject to change.
For the best possible Institute experience and to successfully complete the training, please plan to stay until 4:30 p.m. on Wednesday, October 28. Certificates of completion and the flash drive of training materials will be mailed to those who successfully complete the entire Institute.
I am new to using ASQ:SE-2; is this Institute for me?
The 2015 ASQ:SE-2 Training of Trainers Institute is designed for intermediate-to-advanced ASQ:SE users who already oversee ASQ implementation and training within their organization; participants will leave the Institute prepared to instruct their colleagues on ASQ:SE-2. However, new ASQ users also may find the Institute beneficial to their understanding and implementation of ASQ:SE-2. All participants will receive valuable information to advance their skill level and knowledge of the tools. Please note we will only provide training on the new ASQ:SE-2 and will not cover training on ASQ-3.
I already use ASQ:SE, what can I expect from the new ASQ:SE-2 training?
The Institute is your opportunity to network with colleagues, have questions answered by our expert speakers, and learn about the new features of ASQ:SE-2. Additionally, you will learn how to conduct an introduction to ASQ:SE-2 seminar for your own organization. Please note we will only provide training on the new ASQ:SE-2 and will not cover training on ASQ-3.
Do I need to attend the full Institute training?
Yes, in order to receive your certificate of completion and flash drive of training materials, you must be present for both training days and the appropriate hours and complete the full seminar agenda. Please try your best to plan your flights and travel for after the conclusion of the Institute at 4:30 p.m. on Wednesday, October 28. Please remember to account for your travel time to the airport when making your flight reservations. We recommend that your return flight be scheduled for 6:30 p.m. or later to allow for your complete attendance at the Institute.
I need to leave early on the last day to catch my flight home. Is that okay?
Full attendance is required for successful completion of the training. Please arrange your flight accordingly; the seminar ends on Wednesday, October 28, 2015, at 4:30 p.m. Please remember to account for your travel time to the airport when making your flight reservations. We recommend that your return flight be scheduled for 6:30 p.m. or later to allow for your complete attendance at the Institute.
During the training I will need to call my office for a meeting. Is that okay?
We understand that emergencies occur and that a call to the office may become necessary; outside of emergency circumstances, please try to avoid scheduling calls/meetings while you are in attendance at the Institute. If this is unavoidable, please attempt to limit these interruptions by scheduling them during breaks and lunches. As is noted, full attendance is required for successful completion of the training. Please arrange your business calls and meetings accordingly; the seminar ends on Wednesday, October 28, 2015 at 4:30 p.m.
After the Institute, what can I do with my new ASQ:SE-2 knowledge?
You are being trained to return to your place of employment for the purpose of providing introduction training on ASQ:SE-2 to colleagues within your office/organization/agency. You are not authorized to train on ASQ-3 unless you have completed an ASQ-3 TOT at another time. You are not authorized to train outside of your place of employment or to charge a fee for your training.
What can I do with the handouts and flash drive that I receive at the Institute?
You may duplicate the materials for distribution at training for colleagues within your office/organization/agency. If necessary, you may charge a nominal fee to cover the cost to reproduce training materials only.
Who are the Institute trainers?
Institute trainers are people who have been involved in the authorship, development, and/or research of the ASQ-3 and/or the ASQ:SE-2. All have extensive significance in early childhood and early childhood intervention. Many are currently professors at universities in the United States.
Will I meet any of the ASQ-3 or ASQ:SE-2 authors at the Institute?
Yes! Our Institute trainers are expert speakers and contributing authors on either the ASQ-3, ASQ:SE-2, or both!
What is the registration fee?
The registration fee for an individual is $750.00.
Groups of 4 or more (paying with one organization payment), $690 per person.
Do you offer group rates?
Yes, you can receive a discount on the registration fee when 4 or more persons from the same program attend and register with one payment (by credit card, check, or purchase order).
Visit www.brookesonlocation.com/asq-institute for pricing, group discount rates, and the group registration form.
How do I pay for the training?
You may pay your registration fee with a credit card, check, or purchase order.
When you complete your registration form, be sure to indicate your payment type. Then mail or fax the form and payment to:
Brookes Publishing Co.
P.O. Box 10624
Baltimore, Maryland 21285-0624 USA
Fax: 443-279-0976
Due to the high demand for participation in the Institute, payment must be received at the time of registration form. We regret that we cannot accept or hold any registration forms unless payment accompanies the registration form.
What forms of payment do you accept?
The following forms of payment are accepted by Brookes Publishing:
Credit cards: Discover, Visa, Master Card, and American Express
Check: Please make your check payable to Brookes Publishing and mail to arrive no later than 5 business days after submission of your registration form
Purchase order: Submit your purchase order with your registration form.
Do you accept purchase orders?
Yes, we will be happy to process your purchase order; please submit it with your completed registration form.
What is included in my registration fee?
Your registration fee will include a 2-day training where participants will learn how to lead an ASQ:SE-2 introduction seminar for their own program. Additionally, you will receive practice forms and handouts. Continental breakfast, lunch and light refreshment breaks will be provided for Institute participants each day.
Upon successful completion of the Institute, certificates of attendance, as well as a USB flash drive of training materials, will be sent by mail within one month.
What is NOT included in my registration fee?
Neither your transportation nor your hotel accommodations are included in the registration fee. Each attendee will need to secure his/her own transportation to and from the Institute as well as lodging while at the Institute. Evening meals and entertainment are not included in the registration fee.
The Aloft Chicago O'Hare Hotel is offering a discounted hotel room rate; be sure to mention you are with the ASQ:SE-2 Training of Trainers and the group code ASQ:SE-2 Training of Trainers when making your hotel reservations. Or make your hotel reservation online.
I registered for the training but now I am unable to attend, what should I do?
If you find that you are unable to attend the Institute, all cancellations must be received in writing by mail, fax, or email. Cancellations received prior to September 27, 2015, will receive a 75% refund. Cancellations received after September 28, 2015, will not receive a refund.
If you find that you must cancel but you wish to send a substitute in your place, the substitute must be declared and a new registration form must be completed at least 7 business days in advance of the training.
What is your cancellation policy?
Brookes Publishing Co. reserves the right to cancel the Institute and will inform registrants by September 27, 2015. Should the training be cancelled, full refunds will be issued for the price of the registration fee only. Brookes Publishing Co. will not be responsible for airline tickets or hotel reservations that were booked in conjunction with the Institute.
If you need to cancel, you must notify us in writing (mail, fax, or email). Cancellations received by September 27, 2015, will receive a 75% refund. No refunds will be given after September 28, 2015.
Would I be able to obtain training elsewhere if I am unable to attend this August's Institute?
Yes, through the Brookes On Location program, you can arrange for a trainer to come to your location on the date of your choice. For pricing and more information, email email@example.com or call 1-800-638-3775.
Do you offer discounts on purchases after the Institute?
Yes, at the Institute attendees will receive a 10% discount certificate toward future purchases of any ASQ-3 or ASQ:SE-2 products (excluding ASQ online) when ordered by November 30, 2015.
What should I wear to the training?
Institute attire is casual professional; we recommend dressing in layers as the meeting room temperatures may be cooler or warmer than the temperature outside. You may want to bring a sweater or light jacket to the training.
What is the weather like in Chicago?
In Chicago,
Average high temperature: 63°F (17°C)
Average low temperature: 44°F (7°C)
Average precipitation: 2.5″
Despite what the averages say, weather during this month can vary widely—sometimes it's unseasonably warm, and other days can get downright cold. Packing layers of clothing is definitely in order. Be sure to check the weather forecast before packing your suitcase. A light jacket and umbrella are always recommended, just in case.
What is there to do in Chicago after a long day of training?
There are many local attractions in the area, some close-by recommendations are:
- MB Financial Park at Rosemont is a 200,000 square-foot entertainment and dining complex that opened in 2012 and is home to 12 venues offering upscale international cuisine, live music, comedy, state-of-the-art film, bowling and more. This new entertainment district is a one-stop suburban destination for big city dining, entertainment, nightlife, and family fun. The common area is used for various outdoor seasonal activities, including a climate controlled NHL sized ice rink that is erected in the Winter months for Skating in the Park. Check out the area by clicking on the map. The Aloft Hotel is connected by skywalk to MB Financial Park.
- Fashion Outlets of Chicago is just a quick ride on the Blue Line into the Windy City.
Check out more "Things to Do in Chicago."
What are my options for dinner in Chicago?
Chicago is one of the gastronomical centers of the universe! Take an evening to try some of the city's famed delicacies. Check out OpenTable.com for great recommendations.
If you wish to stay nearby, here is a list of the "Top 30" recommendations by TripAdvisor for the Rosemont area.
Haven't found the answer to your question?
Email firstname.lastname@example.com and we will try our best to answer your question.


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BATMAN #15 to Land in Stores 12/12
Yesterday, "Death of the Family" continued as the eagerly-anticipated BATMAN #14 hit shelves.
From the critically revered and New York Times bestselling creative team of writer Scott Snyder and artist Greg Capullo, the issue made some major revelations about Gotham City's Clown Prince of Crime and his ruthless plans to annihilate The Dark Knight's allies. And with a jaw-dropping cliffhanger for an ending, BATMAN #14 already had us clamoring for more. So what's coming next?
"We've got some really cool, bombastic stuff here. Some explosive stuff," Capullo teased to NEWSARAMA about the upcoming BATMAN #15. "And one of the things that The Joker is good at is getting inside people's heads, right? And so, if he can get in their heads and start to divide and conquer, how much easier is it for him to execute his plan? Which is to destroy the Bat-family. So we're going to start to see the seeds of destruction come to fruit here in this issue. And as we saw, The Joker has possession of Alfred. There's a very disturbing scene in this issue, carrying that ball forward down the field."
Below, take a first look at some interior art from BATMAN #15. For more sneak peeks inside the book, head on over to MTV GEEK, IGN, COMIC BOOK RESOURCES, NEWSARAMA and COMIC VINE, where you'll also get to read more from Capullo about The Joker and what's still to come in "Death of the Family"!
BATMAN #15 lands in stores on December 12.
|Related Links
|Jill Lepore Set for Music Hall's Innovation and Leadership and Writers
December 17, 2014
About Author
- SAG-AFTRA Convention Continues, George Heller Memorial Awards Presented
- Hugh Jackman, Lady Gaga, and More to Appear on THE TONIGHT SHOW STARRING JIMMY FALLON
- David Leitch to Direct THE COLDEST CITY
- SAG-AFTRA Announces Gabrielle Carteris Re-Elected Executive Vice President at National Convention
- VH1's Primetime Ratings For Third Quarter Surge Ahead +34% Over Prior Quarter Among Adults 18-49
- Sara Bareilles, Idris Elba, Adam Lambert, and More to Visit LATE NIGHT WITH SETH MEYERS
- KEVIN HART PRESENTS PLASTIC CUP BOYZ to be Released on Comedy Dynamics 10/13
- The First Lady Joins Public Media Effort, American Graduate Day 2015
- Review Roundup: Matt Damon Stars in Action Adventure THE MARTIAN
- Original Motion Picture Score from Acclaimed Film THE MARTIAN Out Today
- Kaley Cuoco & More Attend Opening Day of MASTERS OF LA
- Mika Kaurismaki's THE GIRL KING Available 12/8
- Sony Classical Releases THE WALK Original Motion Picture Soundtrack Today
- Documentary PINK & BLUE: COLORS OF HEREDITARY CANCER Set for Worldwide Theatrical Premiere Tonight
- Warner Bros. Celebrates Release of PAN by Asking Audiences to 'Discover Your Neverland'
- THE DAILY SHOW's Trevor Noah to Participate In Politicon
- As World Preps or Release of SPECTRE, Gillette Celebrates 'Bond Moments' in Every Man's Life
- Innovid and Netflix Win 2015 IAB MIXX Gold Award
- Director Ridley Scott Incorporates GoPro into the Making of THE MARTIAN
- Special Screening of Documentary SIR IVAN: I AM PEACEMAN to Kick Off Transgender Awareness Campaign


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Kansas-Based Bitcoin Equipment Seller To Reopen
Updated: 12/16/2014 - A Kansas bitcoin company that was shut down after being sued by the federal government will be allowed to reopen.
Updated: 12/16/2014 - A Kansas bitcoin company that was shut down after being sued by the federal government will be allowed to reopen.
Posted: 12/16/2014 - Arkansas City police are investigating a Grinch-like crime in the southwest Kansas town.
Updated: 12/16/2014 - Two Kansas men have pleaded guilty in federal court to operating a synthetic drug business that generated at least $16 million in sales in less than two years.
Posted: 12/16/2014 - The major national lotteries continue to increase and now stand at $113 Million for Mega Millions and $80 Million for Powerball.
Updated: 12/16/2014 - Boxer Jorge Hernandez said "I was actually in shock. I just couldn't believe that it was him. Nothing that we knew of him would lead us to believe what happened."
Posted: 12/15/2014 - The state of Kansas is creating a new investigative unit to combat an increase in cattle theft.
Posted: 12/15/2014 - People with mental illness will be offered two new programs in Topeka beginning in January.
Posted: 12/15/2014 - Envision CEO Michael Monteferrante says the radio acquisition is part of the nonprofit's plan to expand its mission
Posted: 12/15/2014 - The owner of a Wichita auto shop will likely spend the rest of his life in prison after being convicted of killing a man by injecting him with a lethal dose of methamphetamine.
Updated: 12/15/2014 - Police have arrested two people in connection to a weekend shooting that left one man dead and another hurt.
Posted: 12/15/2014 - The 'Aunt Molly and Friends' television show debuts on WIBW-TV next month. The show started production Monday at the Kansas Children's Discovery Center.
Posted: 12/15/2014 - The University of Kansas Endowment has reached a $1.2 billion fundraising goal two years early but officials say the effort will continue.
Posted: 12/15/2014 - K-State won't be the only squad from Kansas playing in the Alamo Bowl on January 2.
Updated: 12/15/2014 - Jurors are weighing life in prison or the death penalty for convicted child killer Billy Davis.
Updated: 12/15/2014 - Police are investigating the death of a woman whose body was found behind a Kansas convenience store.
Updated: 12/15/2014 - The organizer of the Heartland Park petition to force a vote on the purchase of the racetrack should have to post a $46 million bond before a court implemented a stay
Updated: 08/17/2015 - Topeka Police officers find a woman miles away from the home where she shot early Monday afternoon.
Updated: 12/15/2014 - A weapon was found inside the backpack of a student at Indian Hills Elementary School on Monday, according to school officials.
Updated: 12/15/2014 - A woman was killed when she was hit by a truck while walking along Highway 24 early Sunday morning, according to the Pottawatomie Co. Sheriff's Office.
Updated: 08/17/2015 - A 10-year-old Kansas boy is dead and police have arrested a woman in connection to his murder.
Posted: 12/15/2014 - A Lawrence kennel fire that left at least three dogs dead has city officials reviewing fire and pet services codes.
Updated: 12/15/2014 - Thirty-seven registered criminal offenders are enrolled or employed at the six state universities in Kansas.
Updated: 12/15/2014 - The Kansas City, Kansas, police department says Kahlif Hampton died Sunday after being shot in the head on Friday.
Updated: 08/17/2015 - A body found in Pennsylvania is believed to be that of shooting suspect Bradley William Stone, a law enforcement official briefed on the investigation told CNN on Tuesday.
Posted: 12/15/2014 - Scattered thunderstorms are going to continue to be possible throughout the morning hours as a large, defined low pressure system progresses east out of Kansas and the Central plains.


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Hi, I'm new but I realy have a serious question. In my school, we have eight girls who follow the one of those eight. They probably think they're so awesome because they ignore the other girls(7girls). I'm one of these ignored. I really get hurt because of them. 3of them really hate me and rest is so-so. I have to go back to school tommorow and I don't want to face them. How do I have a good time at school when they exist in my class. (No bad words in comments please!)
annelemon 13-15, F 2 Answers 0 Aug 24, 2014 in Dating & Relationships
It happens. Cliquiness is the way of things, particularly at your age. But you can get some humor out of it. Try watching "Heathers." It's worth a laugh if the laugh helps you to see those girls in a different, better light.
Best Answer
The age old problem. This always hard to answer. Being a guy, I would say take the aggressive approach and humiliate the the lead chick somehow, but that may not work for you. Maybe you will get lucky and you have fallen off of their radar.
Best Answer
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i find it disturbing when man get up and pee at a tree! lol!
Do you ever feel like your the boring/annoying person in your group of friend unless you have something to offer?johnnywillsave 26-30, M 4 Answers 3 Jun 16, 2012
youcthrume 36-40, M 5 Answers 1 Mar 26, 2014 in Embarrassing & Funny
We can effectively shut down any and all trolling by keeping a central list ( we shall create a google doc editable by only those confirmed in the group ) and keep it only editable...
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Request a Deal
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About this Business
From Our Editors
Thirty years ago, the Ramos family set out to establish a Mexican eatery that would reflect the hospitality of their own home and feature a menu replete with south-of-the-border staples such as tacos, fajitas, and chimichangas. The fruits of their early labors have since multiplied, and today Don Jose's Mexican Restaurant & Cantina flourishes in three locations. Known for its tangy margaritas and extensive selection of burritos and chimichangas, the restaurant also caters to heartier appetites with macho combos such as the El Presidente, a beef and cheese chili relleno served with a tamale, chicken flauta, and lengthy trade agreement to peruse throughout the meal.
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THE unique little battery commanded by Captain J. J. Schoolfield was invented by a man named Williams, of Covington, Ky., who went to Richmond early in the war and induced the Confederate Government to cast a battery of six guns. This was the only battery of the kind, I think, in the Confederate army. During much of the war it was attached to our brigade, and the twenty-five young men who manned it intimately affiliated with the Fourth Kentucky Cavalry. The names of a majority of the battery membership are to be found on the muster-roll of Captain Bart Jenkins' company.
It was a small breech-loading gun, the breech being thrown out by a spring, when the gun was discharged, thereby permitting a current of air to pass through the long barrel, which had a tendency to keep it cool while being actively worked. It carried a one pound solid ball, but upon occasion it did effective service at short range when loaded with buckshot and half-ounce ball cartridges. The gun could be fired about forty times a minute, and being mounted upon a light carriage it could be run from point to point by hand. The little battery often did great execution, and the Federals were frequently puzzled to know the character of artillery they were fighting.
On one of the inconsequential raids into the mountains of Kentucky Colonel Tom Johnson took one of the little guns with his battalion, but I do not think any of the regular batterymen accompanied it. While encamped somewhere near the Big Sandy River, in a narrow valley, flanked by high mountains, a noted Union partisan, named Patrick, entered Johnson's camp at night and stole the gun away. Patrick told me of the circumstance since the war, and said he was like the man who drew the elephant--that he did not know what to do with the gun after he had captured (?) it. The


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RC Willey's Black Friday Reveal
Posted by Andie on November 25, 2009
Happy Black Friday, Folks! For those of you that are planning your Friday festivities, here's a sneak peak of what you can expect from our Black Friday Ad.
Drum roll please.......................................
Check out just a few of the sweet deals! For the complete ad visit www.rcwilley.com Wednesday at midnight to see all of our incredible offers.
See you Friday!
|2 Comments
|Enter a Comment
|Andie(5 years ago)
Eric, We would love to hear about your experience at RC Willey. Go ahead and shoot your email to me and I'll make sure that it gets to the right person. Thanks! email@example.com
|Eric(5 years ago)
I want to write a note of thanks to R.C.Willey for a particularly good experience with an employee in one of the stores. Is there an email address I can send this to, or does it have to go by snail mail? Thanks, Eric


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Cape Cod Shark Attack Victim Survives
Chris Meyers was attacked by what experts believe was a great white shark.
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10/09/2015 5-8
Park Grill Fall Fest
Come hang out with us at Park Grill in downtown Chicago!
Come hang out with us at Park Grill in downtown Chicago!
We will serving beer at the Festiv-Ale to support the Cystic Fibrosis Foundation! Come visit us and support a great cause!
Beer & Bacon... what could be better? Join us in Chicago for the Beer & Bacon Classic!
A number of lucky IU Alumni will have the opportunity to tour our Sour Ale Brewery during Homecoming!
Come party with us in Bloomington!
We will be doing tastings at the Wisconsin Craft Beer Fest! There will be three tasting sessions so come visit us! (Friday 4:30-9:00, Saturday 11:00-3:30, and Saturday 4:30-9:00)
Bring a dish to share and wear your costume! More details to come!
Come Join us in Celebrating with the Broad Ripple Brew Pub for their 25th Anniversary!
We will proudly be pouring at this years Festival of Barrel Aged Beers in Chicago! Don't miss out on this amazing event!
We will be pouring beer after the ride at this years Gravel Grovel! It'll be a great time and a great ride!
The best weekend of the year is back August 12-14 2016! All the biking, camping, beer, and live music you can handle. Stay tuned for next year's rides!


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National Grid USA
The National Grid is the high-voltage electric power transmission network in the United Kingdom, connecting power stations and major substations and ensuring that electricity generated anywhere in Great Britain can be used to satisfy demand elsewhere. There are also undersea interconnections to northern France (HVDC Cross-Channel), Northern Ireland (HVDC Moyle), and the Isle of Man (Isle of Man to England Interconnector).
Source: Wikipedia
Some of this data may be out of date
State influence data from the National Institute on Money in State Politics changed in format and availability during the 2013-2014 election cycle. While we work to integrate their new style of data release, state-level campaign finance data for the 2014 cycle and beyond will be unavailable. We apologize for the inconvenience, but heartily recommend trying out their snazzy new site at FollowTheMoney.org!
Campaign Finance$1,898,607 Given
Figures are based on itemized contributions reported to the Federal Election Commission and state agencies. Please note that:
- contributions under $200 are not reported, and so are not included in totals.
- only contributions from individuals and organizations to candidates are included. Various accounting measures and more exotic contribution types are excluded.
- contributions are matched based on organization and recipient name reported within each election cycle. Contributions using an incorrect or non-standard version of the name may be missed.
- corporate name changes and mergers may cause figures to differ from those of the Center for Responsive Politics.
- organization totals include known subsidiaries of the organization.
For more information, please see our campaign finance methodology page. Lobbyist bundling data is described on our lobbyist bundling methodology page.
state-level data is not available in bulk for 2014. for current state data, browse http://followthemoney.org/
Top Recipients
- PAC Color Block
- Organization's PAC(s)
- Employee Color Block
- Associated Individuals
Republicans vs. Democratsin dollars. "Other" includes 3rd parties and organizations without official party affiliation.
State vs. Federalin dollars
Top PAC Recipients
- PAC Color Block
- Organization's PAC(s)
- Employee Color Block
- Associated Individuals
Lobbying$27,844,331 Spent
Figures are based on lobbying activity reported to the Senate Office of Public Records. Reported dollar amounts are required to be accurate only to the nearest $20,000. For organizations whose primary business is lobbying, we display total income and top clients. For organizations that are not primarily lobbying firms, we display total amount spent on lobbying and top lobbying firms hired.
For more information, please see our lobbying methodology page.
Lobbying on Behalf of National Grid USA
Names of Lobbyists
Firm Hired Amount National Grid USA $27,844,331
Most Frequently Disclosed Lobbying Issues
- Utilities,
- Taxes,
- Energy & Nuclear Power,
- Finance,
- Homeland Security,
- Environment & Superfund,
- Transportation,
- Fed Budget & Appropriations,
- Natural Resources,
- Banking
Most Frequently Disclosed Bills
Bill No. Title S.774 National Energy Security Act of 2009 H.R.1835 New Alternative Transportation to Give Americans Solutions Act of 2009 S.271 Fuel Reduction using Electrons to End Dependence on the Mid-East (FREEDOM) Act of 2009 H.R.445 Heavy Duty Hybrid Vehicle Research, Development, and Demonstration Act of 2009 H.R.1380 New Alternative Transportation to Give Americans Solutions Act of 2011 H.R.1158 Biogas Production Incentive Act of 2009 S.306 Biogas Production Incentive Act of 2009 S.1462 American Clean Energy Leadership Act of 2009 S.539 Clean Renewable Energy and Economic Development Act S.433 (Unknown)
RegulationsMentioned in 886 dockets; Submitted to 28 dockets
All data is based on documents downloaded from Regulations.gov. The first table shows mentions: all documents that include the name of the company anywhere in the document or document metadata. The second table shows submissions: all documents where the submitter metadata included the company name. Each table shows the top 10 dockets, ranked by number of occurrences.
Matches are based on a search for the company name. Variations in the company name, such as acronyms, nicknames or alternate names may cause documents to be missed. The mention of a company name in a document may be incidental and does not necessarily indicate that the company has any relevance to the document. Company names that are common English words may erroneously match with text that is not referring to the company.
Not all agencies submit public comments to Regulations.gov. For a list of participating and non-participating agencies see here. Agencies that do submit to Regulations.gov have varying levels of accuracy and completeness.
Regulations and public comments can be downloaded in bulk here.
The tables show occurrences of "National Grid USA" in public comments on proposed federal regulations.
Documents Submitted by the Organization
- Submissions
- Agency
- Docket
- Date
View all submissions data for National Grid USA
- Toggle 3 EERE Energy Conservation Program for Commercial Equipment: Energy Conservation Standards for Distribution Transformers Energy Conservation Standards [71FR44356] (EERE-2000-STD-0099) 2006
- Toggle 2 PHMSA Notice of Information Collection Activities 2012
- Toggle 2 EERE Energy Conservation Program for Consumer Products: Central Air Conditioners and Heat Pumps Energy Conservation Standards [76FR36368] (EERE-1998-STD-0089) 2006
- Toggle 1 SEC Comments on Concept Release on the U.S. Proxy System 2006
- Toggle 1 SEC Comments on Proposed Rule: Electronic Recordkeeping by Public Utility Holding Companies 2001
- Toggle 1 PHMSA Pipeline Safety: Public Workshop on Integrity Verification Process 2013
- Toggle 1 SEC Comments on Proposed Rule: Foreign Utility Companies 2001
- Toggle 1 PHMSA Excavation Damage Rule 2009
- Toggle 1 EERE Petition of the Commonwealth of Massachusetts to Exempt from Federal Preemption Massachusetts' 90% Annual Fuel Utilization Efficiency Standard for Non-Weatherized Gas Furnaces 2009
- Toggle 1 EERE Proposed Methodology for Evaluating State Energy Code Compliance 2013
Mentions in Document Text
- Mentions
- Agency
- Docket
- Date
View all mentions data for National Grid USA
- Toggle 95 EPA Standards of Performance for Greenhouse Gas Emissions from Existing Sources: Electric Utility Generating Units 2013
- Toggle 51 EPA National Emission Standards for Hazardous Air Pollutants for Coal- and Oil-fired Electric Utility Steam Generating Units 2009
- Toggle 29 EPA Criteria and Standards for Cooling Water Intake Structures 2008
- Toggle 26 EPA National Priorities List, Notice of Proposed Rulemaking; Gowanus Canal 2009
- Toggle 25 EPA Clean Air Transport Rule 2009
- Toggle 19 EPA Rulemaking for the Steam Electric Power Generating Effluent Limitations Guidelines 2009
- Toggle 18 USCG Liberty Natural Gas LLC, Port Ambrose Liquefied Natural Gas (LNG) Deepwater Port License Application 2013
- Toggle 16 EPA Greenhouse Gas Mandatory Reporting 2008
- Toggle 16 EPA EPA/NHTSA Joint Rulemaking to Establish Light-duty Vehicle GHG Emissions Standards and CAFE Standards 2009
- Toggle 15 PHMSA Meeting of Pipeline Safety Advisory Committees 2009
Advisory Committees4 people on 4 committees
Data is based on disclosures required by the Federal Advisory Committee Act (FACA). Matches are based on the occurrence of the company name in the committee member affiliation. Variations in company names may cause some matches to be missed.
The table shows only the top 10 agencies. To search and download raw records from the complete dataset see the FACA data section.
Table shows employees of "National Grid USA" that sat on federal advisory committees.
- Agency
- Representation
- Toggle Department of Energy 2 people on 2 committees
- Toggle Department of Labor 1 person on 1 committee
- Toggle Department of Transportation 1 person on 1 committee


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"Arrow's True Ivory" is a 4 yr old reg TWH gelding. He is a 15.1 hand perlino. DOB May 5, 2011. Grand Sire is: Blue Gold and Sire is: Arrow's True Blue…$900
Semen from COOL TRAX JAX, the grandson of IMA COOL SKIP and son of INSTANT ATTRACTION, is for sale. Serious intent to purchase will be shown with a deposit…No Price Listed
Shadow is a flashy petite jumping pony. She is walk, trot, canter, and jumps 2ft. She is in her prime at 15 years old. She is very sweet natured. She needs…$1,000
Popeye is a walk, trot, canter, poles green broke Haflinger pony. He is extremely sweet and loving. He is an easy keeper and is barefoot. He ties, loads…$1,000
Mare can jump anything, beautiful mover. Flying lead changes and a good head set. Smooth stop and transition. I would maintain her shots, coggins, and…$300
Roxy is a very sweet and gentle fjord. She would make a great jumping horse , partner for your driving team or just all around riding horse. She is well…$3,500
Stunning dark chocolate with blonde mane and tail proven registered and certified to breed Rocky Mountain mare. Excellent bloodlines, perfect health and…$1,000
Beautiful chocolate with blonde mane and tail proven double registered and certified to breed Rocky Mountain and Kentucky Mountain Saddle horse. We are…$1,000


text:
|Reviews for Santa's Little Helper
| ohnice1 chapter 1 . 1/4/2011
I can't even breathe right now; this was HILARIOUS. Well done!
| Cassicio chapter 1 . 1/4/2011
BAHAHAHAHAHAHAHAHAH! You have NO idea how many times I facepalmed while reading this XD
You gonna keep goin' with this or is it just a one shot thing?
| Butterfly81 chapter 1 . 1/4/2011
I have never laughed so hard at a fic like this one! Oh my god! You caught the characters perfectly, And Rachel, haha so clueless. This is friggin HILARIOUS! You're officially my fave person right now!
| JessicaHayden chapter 1 . 1/4/2011
there needs to more. for serious! I love it!
| Anon chapter 1 . 1/4/2011
OMG AMAZING! Love you for writing this!
Don't. Stop.
| Bladed Darkness chapter 1 . 1/4/2011
Oh Glee... I feel so embarrassed for them, being so confused. Poor Rachel and Quinn. Loved it though.
| Alianne chapter 1 . 1/4/2011
OMG this was so funny and their voices were so spot on. It was amazing how believable the situation was. I can easily imagine Rachel getting into this kind of situation. I hope there is a sequel to this 'coz I'd love to see their reaction when they realize the mistake.
| kiarcheo chapter 1 . 1/4/2011
I feel so bad for Rachel, not having received her gift and not even thanks for having bought something to everyone...but I loved that she stunned everyone with her impromptu solo.
Quinn thinking about sex while Rachel talks about massages...I'm curious to see her reaction when she finally understand...but at the same time, who said that one thing can't turn into the other ;)
Can't wait for the next chapter
| erw-fan chapter 1 . 1/4/2011
I'm laughing so had now that Im very grateful Im alone and nobody can make fun of me. Please tell me there is a continuation to this story!
| Ace Trainer Jessie chapter 1 . 1/4/2011
lamo. great story. omg Rachel is gonna get a surprise when Quinn puts the moves on her...or thinks that Rachel is putting them on her.
| roxystyle011 chapter 1 . 1/4/2011
i'm obviously obsessed and demand you post the next part at once! i'm seriously head over heels in love with your writing and need more of it. even though i knew the premise before reading it, i was still enthralled and didn't know what would come next! how do you do that? absolutely love Quinn's reactions and inner monologues about everything, she has such gems. i was chuckling at the entire 'reveal' scene and the fact that she used tongs so she wouldn't have to touch it. these air quotes are doing nothing to help Rachel's cause and it's hilarious. resolve their misunderstanding at once. although, i'm nervous about what's going to happen when rachel realizes the way quinn took the things that she's already said, because well rachel thinks it's harmless and quinn thinks it's much more...drama on the horizon? how long is it? are they gonnaaa fall in looooooove? ya know what? i'm just gonna text you and demand answers. keep writing! and this needs all of your attention until it's completed. :-)
| L.Wonka chapter 1 . 1/4/2011
| gutter chapter 1 . 1/4/2011
Fuck, hot. Update soon. Gah! Poor Q, naive Rachel. Hahaha.. Please update soon.
| zettev2 chapter 1 . 1/4/2011
You're a freakin' genius! This was awesome. Truly unforgettable.
| Maybe it's better chapter 1 . 1/4/2011
You're truly great! I laughed so hard:D I'm waiting for Rachel to do 'back massage'.


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often hardware manufacturers have web sites, have you looked there?
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It's Packard Bell
In 1986, Beny Alagem and a group of Israeli investors bought the Packard Bell name from Teledyne and resurrected it as a manufacturer of low-cost personal computers. Their computers were among the first IBM PC compatibles sold in retail chains such as Sears.