text:
Your cart is empty!
Fructis Sleek and Shine: The formula with argan oil from Moracco and apricot soaks deep into frizzy, dry hair to smooth each strand.
Proven to Perform
Create and control any style you want with Garnier Fructis Style.
In a frizz test when using Garnier Fructis Sleek and Shine System of Shampoo, Conditioner and Anti-Frizz Serum vs a non-conditioning shampoo.
Water, Cetearyl Alcohol, Elaeis Guineensis (Palm) Oil, Behentrimonium Chloride, Pyrus Malus Extract/Apple Fruit Extract, Glycerin, Fragrance, Isopropyl Alcohol, Stearamidopropyl Dimethylamine, Argania Spinosa (Argan) Kernel Oil, Niacinamide, Pyridoxine HCI, Prunus Armeniaca (Apricot) Kernel Oil, Citric Acid, Saccharum Officinarum (Sugar Cane) Extract, Chlorhexidine Dihydrochloride, Benzyl Alcohol, Linalool, Butylphenyl Methylpropional, CI 15985, Yellow 5, Citrus Medica Limonum (Lemon) Peel Extract, Yellow 6, Camellia Sinensis Leaf Extract, Aminomethyl Propanol, F.I.L. D46632/2.
For hair that shines with all its Strength.
After shampooing, apply conditioner to hair from root to tip, making sure to cover the ends. Rinse. For best results, use with the Garnier Fructis Sleek and Shine System.
This shampoo eliminates the harsh chemicals from the hair like parabens, sulfates, dyes. It contains ginger, aloe, soy protein. It makes my hair soft, and silky. It smells nice. Now a days it is so hard to find it in stores, i got it from myotcstore.com.
The coconut oil conditioner gives refreshing coconut fragrance. There are no harsh salts or sulfates. It is safe for color treated hair. Smoothness and shine of my hair has been increased, my hair has become soft and flexible.
This conditioner is petroleum free, and alcohol free. It leaves my hair extremely thick. It has a nice lemon smell and plant natural smell. This is my single favorite conditioner, it makes my hair thicker and grow faster and longer.
This hair conditioner is Sulfate and sodium free. It is very Safe for color treated hair. This has reduced the amount of itching and irritation for me. It does not leave a residue but does leave my hair shiny and smooth.
This is the most amazing product ever! I've tried basically every shampoo & conditioner brand available, from cheap stuff, to high end salon products, but his is by far the best! I use this as my everyday conditioner. It's super moisturizing, but not greasy at all, even if you put it on your roots! My hair is so soft and frizz-free, I don't even need to use any other product afterwards!


text:
All By Myself
By E. Carmen & Rachmaninoff / Celine Dion
All By Myself composed by E. Carmen & Rachmaninoff / Celine Dion. Arranged by Frank Bernaerts. For Concert Band / Wind Ensemble. Also on the Bernaerts CD: That's Entertainment. Pop music. Medium. Score and set of parts. Duration 4:09. Published by Bernaerts Music (B1.970149-HAR).

subset: commoncrawl


text:
There is no cure for Alzheimer's disease and other forms of dementia, but the research community is one step closer to finding treatment.
University of Washington bioengineers have a designed a peptide structure that can stop the harmful changes of the body's normal proteins into a state that's linked to widespread diseases such as Alzheimer's, Parkinson's, heart disease, Type 2 diabetes and Lou Gehrig's disease. The synthetic molecule blocks these proteins as they shift from their normal state into an abnormally folded form by targeting a toxic intermediate phase.
The discovery of a protein blocker could lead to ways to diagnose and even treat a large swath of diseases that are hard to pin down and rarely have a cure.
"If you can truly catch and neutralize the toxic version of these proteins, then you hopefully never get any further damage in the body," said senior author Valerie Daggett, a UW professor of bioengineering. "What's critical with this and what has never been done before is that a single peptide sequence will work against the toxic versions of a number of different amyloid proteins and peptides, regardless of their amino acid sequence or the normal 3-D structures."
The findings were published online this month in the journal eLife.
More than 40 illnesses known as amyloid diseases Alzheimer's, Parkinson's and rheumatoid arthritis are a few are linked to the buildup of proteins after they have transformed from their normally folded, biologically active forms to abnormally folded, grouped deposits called fibrils or plaques. This happens naturally as we age, to a certain extent our bodies don't break down proteins as quickly as they should, causing higher concentrations in some parts of the body.
Each amyloid disease has a unique, abnormally folded protein or peptide structure, but often such diseases are misdiagnosed because symptoms can be similar and pinpointing which protein is pr
|Contact: Michelle Ma
University of Washington


text:
Pendant Lighting & Pendant Light kits
Pendant lighting will add a sophisticated touch to your room design. Suspended from the ceiling, pendant lights provide a flexible method for determining how much lighting to install in a room. With many different pendant light options to choose from, incorporating pendant lighting into your design will be a breeze.
ET2 - E93738-109SN - Swirl Satin Nickel 7 Light RapidJack Pendant and Canopy with Tangerine Swirl Glass$1,086.00
Sonneman - Teardrop 8 Light Pendant$1,250.00
Carpyen - Mandarina Pendant Large 17" Pendant$1,080.00
Sonneman - Axes 5 LED Pendant$1,170.00


text:
DIY Halloween costumes
Secret ways to let your crush know your true feelings
Cute bracelets for Breast Cancer Awareness month
Tonight: Every Witch Way's Andi is back in Nick's new WITS Academy
It's all about limits this week, Virgo
DIY these pretty bobby pins
Nail polish expires? The *real* shelf-life of your fave beauty products
#Mmmonday: The all-time best after-school snacks
Sneak a peek at our awesome October/November issue starring Bea Miller!
GL's Exclusive Look at GMW's "Girl Meets World of Terror 2"
More Friends = More Fun
GL Tweets !
8 HOURS AGO Lift weights like a total pro with these tips and tricks: http://t.co/UByKLYEmbn pic.twitter.com/bMHHrQlGZy
9 HOURS AGO We're still obsessed with this so-fresh fishtail mani from @hannahroxit: http://t.co/x7UIDp19tM pic.twitter.com/GskKPhFl0N
11 HOURS AGO It's never too early to start prepping for college—seriously!: http://t.co/1Mn8rLOwyA pic.twitter.com/ydSiAgOPNp
sponsored links
Check these out, too...
Throw a trick on a trampoline
Grab a group of girls and guys, sit down in a circle and
play "Down by the banks of the hanky panky."
Find a bucket of chalk and play a game of hopscotch
Do a set of 10 frog jumps (or jump squats)
Watch Amy Adams in Leap Year
Dig up two jump ropes and a few friends, and go double-dutch
Raining? Rock your rainboots and go puddle jumping
Play leapfrog with your sibs
Do a late-winter Polar Bear Plunge. Bonus points if you can
raise money for charity!
Head over to a local elementary school or park and play
Impromptu dance party! Be sure to add "Shout" and "Cha Cha
Slide" to your playlist.
this post? You'll heart these, too!
» Easy DIYs to dress up your spring wardrobe
» How to host a fab boy-girl party
WIN BIG! We're crushin' on pink 'n' red swag all February long.
Want more ways to get
GL? Like us on
Facebook or follow us on Twitter!
POSTED IN boredom buster, get outside, spring fun
Get super spooked with our Bone-Chilling Books giveaway!
Want to score some seriously scary stories this season? CLICK HERE for your chance to win three *terrifying* tomes from Harlequin—just in time for Halloween. Eek!


text:
Bishop T.D. Jakes' MegaFest Kicks Off In Dallas On Thursday
DALLAS (CBS 11 NEWS) – MegaFest, the largest spiritual festival in the nation, kicks off in Dallas on Thursday. More than 50,000 people are expected to attend the event. There's an impressive list of guests that will attend as well — from Oprah to Jennifer Hudson.
"Over the next few days, Dallas, we are going to have a ball in this city from Oprah having her own event, her life class will kick off the event tomorrow morning…to the last hoorah on Saturday evening when we have the women of purpose concert and everything in between," said Bishop T.D. Jakes.
MegaFest will include empowerment sessions, spiritual and inspirational speakers like Joel Osteen, plus a faith and family film festival.
Events will be held at the Dallas Convention Center and the American Airlines Center.
Click here for more information about Megafest, including a full schedule of events.
Latest News:
- Head-On Collision Kills One In Johnson County
- Car Crashes Into Dallas Bridge Beam
- General Mills Finds Listeria In 2nd Batch Of Green Beans
- 24-Year-Old Critical Missing Person Found Safe
- George H.W. Bush Healing Nicely After Summer Spill
Top Trending:


text:
The United States has the reputation of being the Western country where workers receive the least amount of paid vacation days. On average, U.S. workers that have been with the same employer for a number of years are allowed 15 days off and 10 paid vacation days, for a total of 25 days. This actually doesn't sound too bad until one learns that companies in countries such as Brazil tend to offer more than 40 paid days off. In many European countries, including France, workers get two months of paid vacation time annually.
Clearly, heading overseas could offer American workers the potential for many more vacation days. That is also going to be impractical for the vast majority of workers. Below are three careers that offer a compelling combination of days off and decent pay prospects in the U.S.
The teaching profession is often cited as the career with the most vacation days. The general academic calendar will run for a couple of semesters and include a spring break and summer vacation, as well as an extended end-of-year holiday. This could average nearly five months off for post-secondary, with a school session then running the other seven months, on average.
Of course, teachers have a very hectic schedule while classes are in session and often work when classes aren't running. Additionally, pay rates for educators not working for colleges or universities are traditionally low. Professor positions usually pay better. Professors can make more money with consulting work during other parts of the year. This can add up to a compelling combination of high pay, schedule flexibility and actual vacation days.
Financial Services
A popular saying in the stock market is to sell in May and go away. This is meant to imply that much of Wall Street takes the summer off for vacation. It is generally true that the months of June, July and August, which run between Memorial Day and Labor Day, tend to have slower financial market activity. It may not be official time off, as it is with many in the teaching profession, but it can lead to more vacation time. In the financial services industry, banks generally offer generous vacation packages. An employee with at least a few years of service can easily enjoy 20 vacation days plus bank holidays.
Government jobs, be it at the federal, state or local level, used to have a reputation for low pay. In recent years, generous retirement and healthcare packages have advanced total compensation potential and, in some respects, pushed it well ahead of the private sector. These pay benefits may not last forever, but a 40-hour work week and generous vacation benefits are likely here to stay.
The federal holiday schedule includes 10 standard holidays: New Year's Day, President's Day, Columbus Day, Thanksgiving and Christmas. Most workers across the nation also get these days off, but it is more or less guaranteed as a federal worker. After a couple of years of service, the holiday schedule includes another 20 days.
The Bottom Line
In addition to having one of the stingiest holiday schedules in the world, it is often frowned upon for workers in the U.S. to take a lot of vacation days. A study performed by Harris Interactive for JetBlue showed that roughly 57% of U.S. workers don't actually use all of their vacation days. As such, gravitating towards one of the professions above could be a moot point if the respective institution or company guilts its workers about being out of the office, or asks them to work while technically on vacation. However, the above careers at least offer a greater chance of taking some needed rest and relaxation.
Home & Auto
Read This Before Buying a Vacation Home with FriendsGoing in with friends to buy a vacation home will save you on the mortgage and expenses. But if there's conflict, it could end up costing your more.
Just Retired? Check Out These Adventure VacationsGet out your bucket list. No matter what you're passionate about, there's an organization ready to lead the way. Here's a sampling.
How to Save Money on Your Disney VacationUnderstand why Disney Parks are attractive vacation destinations and why they are expensive. Learn five money-saving tips for Disney vacations.
Personal Finance
10 Tips for Renting a Vacation Home on AirbnbHere's a list to make sure that you have a seamless vacation using Airbnb.
Personal Finance
Most Senior-Friendly Cruise DestinationsWhen it comes to choosing a cruise for the post-retirement set, not all destinations are created equal. Here's a handful of the best.
6 Unique Timeshare Ideas for Rich RetireesWhen it comes to timesharing, there's no limit on quirky or wild venues, as vacationers buy shares in castles and tree houses, yachts and train cars.
5 Tips For Vacationing with Young ChildrenMake traveling with young children much less stressful and far more affordable with these five tips.
Best Places to Exchange Currency in HoustonAs an international hub, Houston has plenty of currency exchange places serving visitors and residents. Here's where to find the best rates in town.
Best Places to Exchange Currency in HonoluluTourists have many choices about where to exchange their money in Honolulu. Here are the best places to get a fair deal.
Best Places to Exchange Currency in OrlandoGetting the most bang for the buck in America's amusement-park capital.
What are the warning signs of online hotel / travel booking scams?Travel booking scams ask travelers to book a vacation stay at a residential rental property that is fake or that belongs ... Read Full Answer >>
What country spends the most on education?The United States spends more money educating its young people than any other nation, according to a study from the Organization ... Read Full Answer >>
What's the average salary of a human resources (HR) specialist?The annual salary of human resources (HR) specialists ranges widely. As of 2013, the top 10% earned $95,600, whereas the ... Read Full Answer >>
Who is eligible for a Teacher Retirement?Teachers help to produce the leaders of tomorrow and put forth a lot of hard work and sacrifice to do so effectively. With ... Read Full Answer >>
What's the difference between a CFA and a CPA?There is understandable confusion between different financial professionals and their designations. The difference between ... Read Full Answer >>
I'm a teacher. Which is better for me, a 401(k) or 403(b)? What is the difference? ...The first step is to check with your employer regarding any retirement plan(s) it provides for employees, as you can only ... Read Full Answer >>


text:
Roberts Ranch and Gardens
Spanish Fork
Sign up for the latest news and events about CSA's in Utah.
Salt Lake County, Wasatch Front Farmers Market, Utah Department of Agriculture and Food/Utah's Own, Salt Lake Conservation District, Davis Conservation District, Wasatch Cooperative Market, and Cutler's Cookies.
Thank you for your support!


text:
Since the likelihood of future earthquakes depends on strain accumulation at plate boundaries, the model incorporates parameters for how fast strain accumulates between quake incidences, and strain release that happens during earthquakes.
The authors select the optimal mitigation strategy by using a general stochastic model, which is a method used to estimate the probability of outcomes in different situations under constrained data. They minimize the expected present value of damage, the costs of mitigation, and the risk premium, which reflects the variance, or inconsistency, of the hazard. The optimal mitigation is the bottom of a U-shaped curve summing up the cost of mitigation and expected losses, a sensible balance.
To determine the advantages and pitfalls of rebuilding after such disasters, the authors present a deterministic model. Here, outcomes are precisely determined by taking into account relationships between states and events. The authors use this model to determine if Japan should invest in nuclear power plant construction given the Fukushima Daiichi nuclear reactor meltdown during the 2011 tsunami. Taking into account the financial and societal benefits of reactors, and balancing
|Contact: Karthika Muthukumaraswamy
Society for Industrial and Applied Mathematics


text:
Kia Body & Interior Repair Questions and Answers
Post your Kia body & interior question or share what you know by answering questions
Get your questions answered by the AutoMD Community.
Share your expertise and help others with vehicle questions.
Browse Kia Categories
240 Questions
2002 Kia Sedona EX 6 Cyl 3.5L
Body & Interior - by Roberto Rojo 10/23/2011When start the a/c make a metalic squeer sound
The sound is between the compressor and the belts
2002 Kia Sedona EX 6 Cyl 3.5L
Body & Interior - by Bogle1994 10/23/2011After installing the bulb for the running lights, it blows the fuse how can I fix this?
Brake lights, and turn signal work. After replacing the bulb for the running lights, and reinstalling the light assembly to the body of the vehicle, it blows the fuse.
2010 Kia Soul Sport 4 Cyl 2.0L
Body & Interior - by DALE 10/8/2011WHERE IS THE CABIN FILTER LOCATED AND HOW DO I GET TO IT.
2004 Kia Sedona EX 6 Cyl 3.5L
Body & Interior - by jon 10/6/2011Korean mini van car are they good ? are they reliable car ?
i just wanna know if they are good also
2006 Kia Sorento LX 6 Cyl 3.5L
Body & Interior - by Martha 10/3/2011I just chained the crankshaft position sensor and now my check engine light is on. What could it be?
2000 Kia Sephia Base 4 Cyl 1.8L
Body & Interior - by renee6561 9/30/2011How can i find out if tsb has been performed on my vehicle
door latch, front, front seat belts.
2004 Kia Amanti Base 6 Cyl 3.5L
Body & Interior - by John 9/28/2011Last winter my 2004 KIA Amanti heat stopped working on the left side (driver side) the rest of the heat in the car works
heat works on defrost and the rest of the car.
2004 Kia Optima EX 4 Cyl 2.4L
Body & Interior - by Tom 9/19/2011Driver side power door lock doesn't unlock door. All other door locks work. Even the manual button wont unlock it.
This has happend in the past and it will unlock eventually by continually pushing the unlock button on the remote entry system. (it has now been two weeks of randomly trying the remote and no luck unlocking it yet) Then the next time it is locked the same ...
2006 Kia Spectra5 Base 4 Cyl 2.0L
Body & Interior - by Mustafa Al-Salam 9/15/2011How do I get the lens cover to come off after removing the screws?
My tag light went out after I found out that my bulb socket need replacing. I changed the tail light assembly. When I tried to chage the tag lights, I couldn't get the lens to come off.
2005 Kia Optima LX 4 Cyl 2.4L
Body & Interior - by side 9/11/2011Passenger window goes down but not up when using window control knob, how can correct this?
Control knob let's it go down but not up.
2005 Kia Sedona EX 6 Cyl 3.5L
Body & Interior - by mustang man 9/10/2011All my lights on my van stoped working, i then replaced the bulbs, but burned them out. what could be wrong?
it will turn on and run, but none of the lights will turn on. they told me it was my alternator but i dont think it is, because my van turns on and runs. please if anyone knows i appreciate the help.
2003 Kia Rio Base 4 Cyl 1.6L
Body & Interior - by Andy 8/30/2011What problem cause horn to work intermitintly?
horn works standing still but not always while moving.
2008 Kia Rio LX 4 Cyl 1.6L
Body & Interior - by mike 8/25/2011How to remove driver inside door handle
door willnt open from inside drivers door
2007 Kia Sedona EX 6 Cyl 3.8L
Body & Interior - by 67bird 8/22/2011Both low beam headlights went out at same time and fuses and bulbs appear to be good please help
could it be the automatic night sensor that turns lights on at dusk? If so where is it and how can i test it ? Thanks Clint
2004 Kia Optima EX 6 Cyl 2.7L
Body & Interior - by Chuck Kitchen 8/19/2011Cannot open driver door without quickly locking and unlocking door. Other 3 doors work properly.
Could this be the actuator on the drivers door going bad or some other component?


text:
Hours before President Obama arrived in Oregon, hundreds of protesters lined the roads surrounding Roseburg Regional Airport.
Photo Galleries
President Barack Obama says the American people will eventually have to "come together" to figure out how to prevent deadly mass shootings like one that took place in Oregon last week.
Holding signs saying the president was not welcome, more than 200 gun-rights activists protested Barack Obama's visit on Friday to Oregon to meet with the families of victims of last week's campus killings.
Those gazing at Mt. Rainier Friday morning at just the right time were treated to quite a show, with a dark streak across the sky lifting from the mountain's peak.
A man is facing several charges Friday morning after a stabbing victim was dropped off at a Vancouver-area hospital with life-threatening injuries.
Despite firefighters' efforts to save them, two men died in an apartment fire Friday.
A number of South Carolina residents near the coast are evacuating and others are piling up sandbags anew outside homes and businesses, bracing for more possible flooding even as the nation's Homeland Security chief is set later Friday to tour areas hit hard by recent heavy rains.
President Barack Obama is visiting Roseburg a week after the mass shooting on the Umpqua Community College campus. His arrival was met with mixed reaction from the Roseburg community.
Lexus has revealed an origami-inspired car that ditches the sheet metal, glass and plastics for precision-cut cardboard.
An early morning fight between two groups of students escalated into gunfire in the parking lot outside an Arizona university dormitory, leaving one person dead and three others wounded, authorities said Friday.
A 12-week-old kitten who was shot in the head was found clinging to life in a Portland dumpster last month.
The victims of the deadly Oregon college shooting ranged in age from 18 to 67 and included several freshman students and a teacher.
When President Barack Obama arrives here Friday, he will find a timber town still in mourning over the shooting that killed eight community college students and a teacher. But he will also find another deeply held emotion - seething anger over his calls for new gun restrictions.
Stan Herd, a Kansas-based landscape artist, recently completed his very own museum-worthy masterpiece. Only, it can't be moved because it's actually made out of plants growing in a field!
Airman 1st Class Spencer Stone, who helped subdue an attacker on a French train in August, was stabbed in California and is in stable condition, an Air Force spokesman said.
The Tokyo Motor Show, opening to the public Oct. 30 at Tokyo Big Sight convention hall, will be packed with futuristic eye-catching vehicles that drive themselves, offer online information in dazzling ways and are so green they are zero-emissions.
One of the three Americans who helped foil a terror attack on a train bound for France is recovering from a stab wound, according to reports from ABC News.
There'll be no arguing with the driver on this bus: the rides are free and there's no driver anyway.
The pungent stench of mildew greeted Asiah Lewis when she came home to her apartment, her footsteps making squishing sounds on the carpet as she picked through soggy clothes piled on a bed and a lifted a moldy shoe from the floor.
Mercy Medical Center in Roseburg confirmed that 30-year-old Chris Mintz was released less than a week after being shot seven times.


text:
Fort Lauderdale Marriott
Harbor Beach Resort & Spa
3030 Holiday Dr., Fort Lauderdale, FL 33316
Sponsored by the Cardiovascular Research Foundation
Supported through a grant from ABIOMED, Inc.
Only practicing US and Canadian interventional cardiologists are eligible to participate. There is no cost to apply.
For more information, please contact Catherine Brosnan at firstname.lastname@example.com.
Sponsored by
Supported through a grant from
ABIOMED, Inc.


text:
Hotel is close to main roads and the Hollywood beach. Also has a central location if you want to drive to nearby cities (Ft. Lauderdale, Weston, Pembroke Pines, Aventura). It has a wonderful, well kept golf course (this was the view from our room).
The room we stayed in was large, beds were comfortable and everything (including the bathroom and fridge) was clean.
Room service lady (Robin) even found a piece of jewelry we thought we had lost and left it on a table with a note for us.
All and all great value for your money. Would definitely stay there again.


text:
We've all experienced it. A new book is released, and the author hits site after site after site to promo it.
It doesn't take long to bore the crap out of everyone in the community with this tactic. The first day, we're thrilled. The second day, we smile and nod and may even read the post. But as the tour progresses, more and more people shut down to it. "Enough already! You have a new book out. I get it. I even bought it. During the length of your book tour, I've read it twice!"
Unless you're a die-hard fan of the author, you probably don't hang in there until the end. I bet even the author is sick of it by the time the last stop on the tour is reached.
Why do they do it? To reach readers and rack up sales. There is no other reason. But the problem with the long book tour is 99% of your audience have seen the first two or three tour posts and aren't interested in the rest because they are in the community. They're plugged in, they get the news and hear the rumors, so any tour lasting longer than a few days, a week tops, is pointless and, worse, annoying. Continue reading


text:
Last Chance Foods: The Wild Side of Salmon
There's good news and bad news coming from Alaska and it doesn't have anything to do with politics. First, the good news: it is wild salmon season. Wild salmon have just started to swim upstream to spawn and the fish are currently at their plumpest and tastiest. During their single-minded dash to reproduce, the salmon don't eat and get skinnier as the season goes on.
Now for the bad news. The headwaters of the largest salmon run in North America are threatened by possible industrialization, according to Paul Greenberg, the author of Four Fish. According to Greenberg, a company called Anglo American is seeking to establish a copper and gold mine in Bristol Bay, "the breadbasket of Alaskan salmon."
"In concentration, the mine, which is called Pebble Mine, is more sulfur than it is copper, so you can imagine just the tremendous impact all the slag from this mine could have on what is just a beautifully pristine area," said Greenberg, pictured below with his first Bristol Bay catch of the year, a wild chum salmon from the Nushagak River. Greenberg claims that the copper from the mine also threatens the salmon's migrating ability, which is partly based on smell. Approximately 40 million sockeye salmon travel through the Bristol Bay area each year — and sockeye are just one of five types of wild salmon native to the region.
For now, wild salmon stocks in Alaska are thriving and an environmentally responsible choice of seafood. "It's now part of the Alaska state constitution that fisheries have to be managed sustainably," said Greenberg, adding that almost all Alaskan fisheries are certified by the Marine Stewardship Council.
"With salmon, unlike a lot of fish, you really know how many there are and how many you can take. Why? Because salmon come into the rivers. We can literally count how many came in and figure out how many we need to let go by and get up river to spawn," Greenberg said.
In terms of health, wild salmon provide a good source of protein, untainted with dyes or additives. "Certain species of salmon, particularly the sockeye salmon, are very, very low in toxins," Greenberg noted. "Sockeye salmon eat very low on the food chain. They're practically filter feeders. They eat little, tiny krill," which means they are low in toxins and mercury.
The process of farming salmon has also improved in recent years. Greenberg explained that while it used to require six pounds of ground fish to produce one pound of wild salmon, that ratio is down to less than two pounds of feed for each pound of salmon. On the other hand, some farmed salmon still pose a threat to the environment, since the pens in which they are grown are sometimes placed in rivers where salmon migrate. The dense group of salmon then produce a large amount of waste and create a breeding ground for parasites like sea lice. Greenberg said that some salmon farms are starting to used containment methods to produce salmon, which keep the farmed versions out of streams.
When it comes to shopping at the grocery store, wild salmon like sockeye are easy to spot. With sockeye salmon, the flesh is evenly red, instead of a light pink, and it generally doesn't have the white stripes of fat present in other farmed varieties.
Try New York Times writer Mark Bittman's recipe for Salmon Roasted in Butter, from his book How To Cook Everything. "[This recipe] allows the natural complexity of wild salmon to come out," said Greenberg.
"Farmed salmon tends to have kind of a one-note, fatty-salmony flavor, whereas a wild sockeye has a spectrum of tastes. Because wild sockeye is naturally leaner than farmed salmon, the use of butter here works really well."
Salmon Roasted in Butter
From How to Cook Everything by Mark Bittman
Makes 4 to 8 servings
Time: 15 minutes
- 4 tablespoons (1/2 stick) butter
- 1 (2- to 3-pound) salmon fillet (skin-on is nice), preferably king or sockeye
- Salt and freshly ground black pepper
- Minced fresh parsley leaves for garnish
1. Preheat the oven to 475 degrees F. Melt the butter in a medium roasting pan-either on top of the stove or in the oven as it preheats -- until the foam subsides. Sprinkle the salmon with salt and pepper.
2. Put the salmon in the butter, flesh side down, and put the pan in the oven. Roast about 5 minutes, then turn and roast 3 to 6 minutes longer, until the salmon is done (peek between the flakes with a thin-bladed knife). Sprinkle with a little more salt if you like and serve.


text:
Products & ServicesSee also: Categories | Featured Products | More Information
Enclosure Air Conditioners - 33,000 BTU Energy-Saving, Row-Based Air Conditioning Unit with Hardwire Input -- SRXCOOL33KSupplier: Tripp Lite
Description: Key Features 33,000 BTU (9.7kW) of cooling power with 1/3 less power consumption Variable-speed, DC-inverter-driven compressor and microprocessor-controlled electronic expansion valve (EEV) enable precision cooling adjustments--no more wasteful, noisy cycling between off and full blast
- Cooling Capacity: 9.67 kW
- Operating Voltage: 230 VAC
- Frequency: 50 Hz, 60 Hz
Supplier: Avago Technologies
Description: gate drive optocoupler comes in a compact, surface-mountable SO-16 package. The ACPL-344JT is designed for use in traction power train inverter, power converter, battery charger, air conditioner and oil pump motor drive for electric vehicle (EV), hybrid electric vehicle (HEV) and plug-in hybrid
- Optocoupler Input: DC
- Rise Time: 1.17E-9 minutes
- Collector Emitter Breakdown Voltage: 6 volts
- Operating Temperature: -40 to 257 F
Heat Pumps - Inverter Products:IL Performer 19 Series Mini-Split Ductless Air Conditioners and Heat Pumps -- KSIL012-H219Supplier: Klimaire Products, Inc.
Description: conditioning and heating installation with this high energy efficient unit. Features: 12,000 Btu/h - Energy Star 19 SEER - 208-230 V / 1 ph / 60 Hz DC inverter mini-split air conditioner & heat pump Golden fin - Self clean Follow me comfort function Auto re-start Optional low ambient kit
Air Conditioners - KSIM Multi Zone Inverter Series: Air Conditioners and Heat Pumps -- KSIM30912-H216Supplier: Klimaire Products, Inc.
Description: Klimaire KSIM multi zone inverter series, air conditioners and heat pumps, operates up to four indoor units installed in different rooms, each indoor unit being operated with its own wireless remote control, allowing the individual user to set its individual comfort settings of its own space
- Type: Ductless, Split
Supplier: Panasonic HVAC
Description: Panasonic Flexi Multi wall mounted air conditioners offer the utmost in versatility in solving your cooling and heating needs. By utilizing environmentally friendly R-410a refrigerant and DC Inverter technology, the Panasonic Flexi Multi wall mounted air conditioner, automatically adjusts its
- Type: Window
- Industry: Commercial, Residential
- Cooling Capacity: 4.98 kW
- Operating Voltage: 230 VAC
Supplier: United Refrigeration, Inc.
Description: Sanyo's Ductless Split Air Conditioner & Heat Pump products offer wide versatility in solving your cooling and heating requirements. The Indoor unit(evaporator) is mounted inside the room, enclosed in a handsome space saving cabinet. It is connected to the outdoor unit(condenser) via refrigerant
- Type: Ductless, Split
- Operating Voltage: 230 VAC
- Phase: Single Phase
Supplier: Panasonic HVAC
Description: Panasonic Flexi Multi wall mounted heat pumps offer the utmost in versatility in solving your cooling and heating needs. By utilizing environmentally friendly R-410a refrigerant and DC Inverter technology, the Panasonic Flexi Multi wall mounted heat pumps, automatically adjusts its performance
Supplier: Heat Controller, Inc.
Description: 'V' Series Inverter Inverter Technology for efficiency and comfort Our "V" Series mini-splits utilize inverter technology to reduce temperature fluctuations while saving up to 40% on energy consumption (compared to a standard mini-split). Basically the inverter allows the compressor to run
- Type: Ductless, Split
- Industry: Commercial, Industrial, Residential
Supplier: Electric Generators Direct
Description: High Current Surge Output •Will start most 13,500 btu high efficiency RV air conditioners •2400 watts max, 2000 watts continuous output Inverter System with Pulse Width Modulation (PWM) Control •Safely power computers and sensitive electronics Smart Throttle™ •Engine
- Fuel Type: Gasoline
- Phase: AC Single Phase Power
- Applications: Power
- Frequency: 60 Hz
Find Suppliers by Category Top
Featured Products Top
Tripp Lite
Energy-Saving, Row-Based AC Unit
consumption. Variable-speed, DC-inverter-driven compressor and microprocessor-controlled electronic expansion valve (EEV) enable precision cooling adjustments--no more wasteful, noisy cycling between off and full blast. Soft-start feature limits inrush current to prevent introduction of line noise, voltage disruptions and potential circuit overloads. Self-contained, zero-maintenance unit re-humidifies condensate and expels it through the exhaust air stream -- no floor drain, water collection... (read more)
Browse Air Conditioners Datasheets for Tripp Lite
Fairchild Semiconductor
Smart Power Modules -Leading Efficiency
Fairchild's New SPM ® Smart Power Modules Deliver Industry-Leading Efficiency. High Performance and Compact Solutions for Power Motors Under 100W. Worldwide, small electric motors – like those in dishwashers, air conditioners and fans – account for up to 50 percent of total global energy consumption. With growing consumer demand for these appliances, power management solutions that maximize efficiency are a necessity for a greener and better future... (read more)
Browse Power MOSFET Datasheets for Fairchild Semiconductor
Avago Technologies
Automotive R²Coupler™ Smart Gate Drive
battery charger, air conditioner and oil pump motor drive for electric vehicle (EV), hybrid electric vehicle (HEV) and plug-in hybrid electric vehicles (PHEV) applications. The device satisfies automotive AEC-Q100 semiconductor requirements. (read more)
Browse Optocouplers Datasheets for Avago Technologies
ROHM Semiconductor USA, LLC
ROHM Silicon Carbide Schottky Diodes
recovery time than Si fast recovery diodes; High breakdown voltage; Low power loss; High operating temperature; Superior thermal conductivity; and Highest current rating at 600 V (a true 600 V/20 A SBD, not dual 2x10 A). Ideal applications include: PFC/power supplies, solar panel inverters, uninterruptible power supplies, air conditioners, and motor drivers. (read more)
Browse Diodes Datasheets for ROHM Semiconductor USA, LLC
Avago Technologies
Automotive R²Coupler™ Smart Gate Drive Optocoupler
functional safety requirements. The ACPL-32JT is ideal for use in automotive powertrain traction inverter, power converter, battery charger, air conditioner and oil pump motor drive for electric vehicle (EV), hybrid electric vehicle (HEV) and plug-in hybrid electric vehicle (PHEV) applications. The ACPL-32JT expands Avago 's automotive R2Coupler ™ family of products and is intended to further simplify automotive multi-channel IGBT driver board design. By integrating the flyback controller... (read more)
Browse Optocouplers Datasheets for Avago Technologies
Flexicon Corporation
Sanitary Manual Bag Dumping Station
assembly to separate from the valve body for sanitizing of all material contact surfaces, and to close securely in seconds, also without tools. A high velocity vacuum fan draws airborne dust from the operator's atmosphere onto two cartridge filters. Automatic reverse-pulse filter cleaning allows continuous, efficient operation; timer-activated solenoid valves release short blasts of compressed plant air inside cartridge filters causing dust build-up on the outer filter surfaces to fall... (read more)
Browse Dumpers, Tilters, and Inverters Datasheets for Flexicon Corporation
More Information Top
New White Goods Report - China - 2014
12 China�s inverter air conditioner total shipment forecast, 2014-2018................................................................................
An Influence of Air Volume Flow Rate and Temperature Set Point on Performance of Inverter Split?Type Air?Conditioner
Shao, S., Shi, W., Li, X., and Chen, H., ��Performance Representation of Variable-speed Compressor for Inverter Air Conditioners Based on Experimental Data,�� International Journal of Refrigeration 27:805�815 (2004).
A study on dynamic behavior of load supply system including synchronous generators with and without load drop
Rated Voltage Non- inverter Air Conditioner .
Inverter Air Conditioner Exporters, Inverter Air Conditioner Selling Leads
Search inverter air conditioner .
Modeling air conditioner load for power system studies
Q of the inverter air conditioner is invariant with voltage and frequency.
Mechanical and Aerospace Engineering, ICMAE2011 - Chapter 20: Manufacturing Process Planning and Scheduling
In this paper, we determine the fuzzy control strategy of inverter air conditioner , the fuzzy control model structure, the neural network and fuzzy control technology, structural design of the fuzzy neural network controller as well as the neural network predictor FNNC NNP.
CR4 - Thread: Inverter Air-Conditioners
wikipedia.org " inverter air conditioners " .
Measurement of the influence of household power electronics on the power quality
The influence of the modern, domestic energy saving lighting and inverter air conditioners , as significant household consumers, on the power quality of the electrical energy is considered.
Solar?powered air conditioner
A PV array was connected in parallel with the rectifier of an inverter air conditioner through a converter.
Shopping In Air Conditioners - Big Bruin
� Klimaire 4 Zone Multi Split 4 x 12,000 Btu Ductless Wall Mount - DC Inverter Air Conditioner -Heat Pump-16 SEER-220 V with Complete 16 ft Quick Installation Kit Set of 4 .
Shopping In Air Conditioners - Big Bruin
� Klimaire 3 Zone Multi Split 3 x 12,000 Btu Ductless Wall Mount - DC Inverter Air Conditioner -Heat Pump-16 SEER-220 V with Complete 16 ft Quick Installation Kit Set of 3 .
Laboratory investigation of the input current characteristics of modern domestic appliances for varying supply voltage conditions
3.3 kW split system Inverter Air Conditioner .
Study of Neural Network PID Control in Variable-frequency Air-conditioning System
In [4] the characteristics such as ITAE, coefficient of performance (COP) and the control precision have been compared in fuzzy control and traditional PI control for inverter air conditioner .


text:
Treasury two-year notes reach their 5 months High as the U.S. economy unexpectedly lost jobs in December, giving a signal that the labor market has yet to emerge from its worst slump since World War II.
Yield difference Between 2- and 10-year U.S. debt widened
Between 2- and 10-year U.S. debt the yield difference has been expanded to near the most ever before that the Treasury sells $84 billion in notes and bonds next week.
Continue reading U.S. 2-Year Notes reach 5 Months High as Jobs Decline


text:
Due to vendor restrictions this product does not qualify for this offer.
World's Largest Aftermarket Motorcycle Parts and Accessories Superstore!
Input the part number and quantity to add a part directly to your cart.
Due to vendor restrictions this product does not qualify for this offer.
Continue Shopping
Everyday Low Price: $59.99
Gold Club Price: What's This? $53.99
J&P Part: ZZ47472
Gold Club free ground shipping
Fitment Note: For 2-1/4" exhaust systems.
This product was proudly made in the USA
Diameter: 2-1/4″ O.D.
Manufacturer Part Number: BA-1100-00
Sold in Units: Each
Style: Extreme Slash
One bad *** piece, wish it were a two pack, but let me tell you it really makes my pipes look great!
Call Us 24/7 1-800-318-4823


text:
Ibis Budget Beziers Centre Palais Congres
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
How has this hotel rated in the past?
TripAdvisor Reviews Ibis Budget Beziers Centre Palais Congres Béziers
Travel Blogs from Béziers
2nd Early Ride & Only One More Day BOOHOO
... swim. Mum and Dad got 49 hits without stopping. Mum and Me did 19 maximum. It is so much fun.
We were starving so so we headed to McDonalds. After McDonalds we headed to the Carrefour and got dinner. Its our last time at Carrefour.
We got home to finish all the washing and do our blogs before an early tea. We leave here tomorrow and noone is looking forward to leaving.
Bon Soir
Montpellier for Day Shopping
... cafe called Georges Cafe.
In that there was good and bad news. The bad news was that we got lost. ( Twice.) ( Which is only a thing tourists like us do.) Plus the good news was that we found a really cool TinTin shop.
In the shop there were really cool plastic Portraits and statues of him. After we finally found Georges cafe. For a drink we had ...
A mixed day
... golden vases in front of him was in fact the holy grail - and I, like Indy received a full "you chose well". Yes! Only mine was commented by Nicky, not some 900 year old man from the Crusasades. (Btw, if you not seen the movie, none of what I've just written will make any sense whatsoever!!!!).
Our hotel was delightful. The owner was charming. It was a stunning 1900's grand house that had been completely been refurb'd to a high standard and decorated in a ...
... we drove to an olive farm. We were greeted by 2 very friendly dogs which reminded me of home. Jesse Ray would love this lifestyle I think. We hopped on a tractor drawn carriage with bench seats and driven by the farm manager though the groves. He told us a great deal about olive farming and the different types of olives, it was really very interesting. Our driver did most of the translating although Chris and Helen speak ...
... expanse of sand. I grabbed a beer from a marquee on the beach and then shoes off, we walked along the seashore. Lots of families having fun; we didnt go in as did not have time for all that palava, but getting feet wet wwas sufficient.
Then we walked to the port, rested a bit, before bus back to beziers bus station. This meant we didnt have to walk up through the park, and was a wise move! Picked up luggage and then down ...


text:
McGladrey LLP Audit Associate Interview Questions
Interview Experience
Interview Experience
Getting an Interview
Getting an Interview
Interview Difficulty
Interviews for Top Jobs at McGladrey LLP
- Audit Associate (48)
- Assurance Associate (25)
- Intern (21)
- Tax Associate (21)
- Consulting Associate (12)
- Tax Intern (10)
- Tax (8)
- Assurance (7)
- Audit Intern (6)
- Audit (5)
- Intern - Hourly (5)
- Summer Leadership Program (5)
- Tax Senior Associate (5)
- Associate (4)
- Consulting (4)
- Audit Senior Associate (4)
- Senior Audit Associate (4)
- Accounting (3)
- Director (3)
- Assurance Intern (3)
- Senior Associate (3)
- Staff Accountant (3)
- Internship (3)
- Pathways Program (3)
- Consulting Manager (2)
- Audit Manager (2)
- Advisory (2)
- Auditor (2)
- Senior Tax Associate (2)
- Administrative Assistant (2)
48 Candidate Interview Reviews Back to all InterviewsSort: Popular Date Difficulty
Audit Associate Interview
I applied through college or university. The process took 2 weeks. I interviewed at McGladrey LLP (Atlanta, GA) in April 2015.
I was referred to the job by a professor so that expedited the interview process. An interview was set up within a week. I was interviewed by 3 people, and they were very casual interviews. A lunch with the team followed that. Overall, it was a great experience. I was disappointed when I didn't get an offer.
Interview Questions
- Tell me about yourself - not your elevator speech, but just about yourself. Answer Question
Other Interview Reviews for McGladrey LLP
Audit Associate InterviewNo OfferDifficult Interview
I applied through college or university. I interviewed at McGladrey LLP.
It was through our school career website. It didn't take more than a week. A HR called me and asked several basic questions, such as what is my GPA, where I was academically, and interest... The lady was really nice and friendly.
Interview Questions
- I had to take an Auditing exam, which was really hard. They require the score needs to be above 90%. Answer Question
Audit Associate InterviewNo Offer
I applied online. The process took 3 weeks. I interviewed at McGladrey LLP.
Campus Recuiter, gave them my resume. Applied through school career center and their website. Had an on campus interview, then interview in their office. Did not hear back for weeks so knew it wasn't the right position for me.
Interview Questions
- How many bullets would you fit in this room? 1 Answer
Helpful (3)
Audit Associate InterviewAccepted OfferPositive ExperienceEasy Interview
I applied through college or university. The process took 2 weeks. I interviewed at McGladrey LLP.
Met at career fair, applied through university, had 2 interviews- 1 at school and 1 in office Interviews were very easy and casual, no analytic questions Office interview contained 2 interviews plus presentation
Audit Associate InterviewNo OfferAverage Interview
I applied through college or university. I interviewed at McGladrey LLP.
On campus interview for their office in NY. They have a no stress interview which means they don't ask you questions. So unless you have a really awesome partner you can gel with the interview can get really awkward. My best advice is just to let them do all the talking.
Interview Questions
- So what do you want to talk about. Answer Question
Audit Associate InterviewAccepted OfferPositive ExperienceEasy Interview
I applied through college or university. The process took a week. I interviewed at McGladrey LLP (Los Angeles, CA) in October 2014.
Very Relaxing. Conversational interview. Basic questions. All the candidates were welcomed in the board room of the office after being given an office tour. We then split up each into a room and Partners and managers would come by each room and interview for about 30 minutes until another came by.
Interview Questions
- Give me an example of a time when you worked on a team? Why do you want to work here opposed to Big 4 Answer Question
Helpful (1)
Audit Associate InterviewNo OfferPositive ExperienceAverage Interview
I applied through college or university. The process took a week. I interviewed at McGladrey LLP (Normal, IL) in September 2014.
It was pleasant and very easy going. They invited me out for appetizers and drinks the night before. They also have greeters who you can get the nerves out before the actual interview.
Interview Questions
- Tell me about yourself? When was a time you were faced with a difficult decision and what did you do? Answer Question
Helpful (1)
Audit Associate InterviewAccepted OfferPositive ExperienceAverage Interview
I applied through college or university. The process took 3 weeks. I interviewed at McGladrey LLP.
On campus interview by a senior manager, who was accompanied by a few first years. The next day I was invited to head down to the office for more interviews. For the in-office interview, I interviewed with four people - a senior, a supervisor, a manager, and a partner.
Interview Questions
- Be prepared to ask a lot of questions during the interview. In my case, more than one of the interviewers essentially asked me to interview them. Answer Question
Helpful (12)
Audit Associate InterviewNo OfferPositive ExperienceDifficult Interview
I applied online. The process took 2 weeks. I interviewed at McGladrey LLP (New York, NY) in October 2013.
I was not hired for what I applied for, but I record excellent detail that I'm willing to share. A McGladrey interview will almost be 80% based on your personality, a few behavioral questions, and lots of "tell me about yourself" stuff. They're definitely just getting to know you as a person. Your qualifications to do the job is the main reason the interview is provided--they know that you can do the job, because they'll most likely put you to a formal training program anyway. It's as described by many: Breakfast/Lunch/Dinner, by some employees of the firm, to help ease your nerves. Whether or not they have any power in your hiring, that's unknown. Better be nice to everyone. We had a nice relaxing lunch with all the other candidates. Learn a little bit about the firm, the benefits, all that jazz. After lunch, the candidates went their separate ways to meet their respective interviewers. They'll each tell you a little bit about themselves before they get to the real deal. For me, I had an Audit Partner interview me. Nope. I can feel I sucked. Why? He did not seem very pleased to even be doing interviews, which was an immediate sign that I was not going do well, or have a fair chance. He was interviewing my INTEREST in the position by asking if I have any questions about the job; I had a few, but not enough to last 10-15 minutes conversation. But being that I've always dreamed about being a part of McGladrey and for my dream career choice, what didn't I already know? This was my fault; should've prepared better. It's not an interview about how much you want the position & company, it's about showing the ambition you want for yourself in YOUR career. He had NOTHING scripted, and it was all spur of the moment questions...well, in my case, expecting me to have questions for him. Interview #2 was with a junior HR person. It was more formal, with the questions I've prepared for in personality questions and a few behavioral. Definitely felt I aced it. But again, I think most of the hiring powers come from Partners. If not, you probably need the approval of both. I already knew I was a lost cause, and accepted defeat after all this. Below, I share with you some questions in exact form:
Interview Questions
- 1) Tell me about yourself 2) Why do you want to work with McGladrey? 3) Why did you not apply for the Big 4? 4) Why public and not private? 5) Why do you like Audit? (or whatever your position is) 6) Tell me about a time you made a mistake, and how you dealt with this? 7) Run me down with your resume 8) Do you have any teamwork/leadership skills? **Have some questions ABOUT the position you're applying for, even if you know most of it already, to show interest. Be ready to wing random moments of conversation** 1 Answer
Audit Associate InterviewNo Offer
I was surprised at how relaxed and conversational the first interview went. The employees were all extremely informative and excited to tell you about their experience at McGladrey. Most of the interview we discussed my abroad experience and some past work at my internship.
Interview Questions
- There was nothing unexpected or difficult! Answer Question
Is this helpful? The community relies on everyone sharing – Add Anonymous Interview Review


text:
Quark: Season 1, Episode 6
All the Emperor's Quasi-Norms: Part 2 (31 Mar. 1978)
We start with a recap of last week's episode and find out that Zorgon the Malevolent is pleased that Quark has directed him to the asteroid Rumbar and "It." As a reward, Zorgon decides to ... See full summary »
Director:Bruce Bilson
Writers:Buck Henry (creator), Jonathan Kaufer


text:
All materials on Kansas Memory are made available for noncommercial educational and research purposes only. It is the patron's responsibility to request and obtain permission from both the image and copyright owner(s) to use materials.
To obtain permission or to purchase a reproduction, please contact the KSHS Reference Desk at 785-272-8681, ext. 117 or email@example.com. See the Copyright and Permission FAQ for more information.
This sepia colored photograph shows the twenty-seventh President of the United States William Howard Taft on the south steps of the capitol in Topeka, Kansas. He spoke to the crowd of citizens and civil war veterans who were attendance for the Semi-Centennial State Wide Reunion of the Grand Army of the Republic. Prior to the speech, President Taft dedicated the cornerstone of the G.A.R. Memorial Hall building at Tenth and Jackson Streets, east of the capitol, in Topeka, Kansas
Date: September 27, 1911
Item Number: 303102
Call Number: FK2.S5 T.56.1911 *2
KSHS Identifier: DaRT ID: 303102
Built Environment - Areas of Significance - Politics/Government
Built Environment - Function - Government - Capitol
Collections - Photograph
Date - 1910s - 1911
Government and Politics - Federal Government - Presidents - Taft, William Howard, 1857-1930
Government and Politics - Political Parties - Republican
Military - Veterans - Organizations - Grand Army of the Republic (GAR)
Military - Wars - Civil War
Objects and Artifacts - Communication Artifacts - Documentary Artifact - Photograph
People - Notable People - Taft, William Howard, 1857-1930
Places - Cities and towns - Topeka
Places - Counties - Shawnee
Type of Material - Photographs


text:
Robin D Cuzzort
Columbia, SC
Get contact information on Robin D Cuzzort, Columbia SC. Find out Robin D Cuzzort's age, gender, possible aliases, associates, professional, and education info.
Also Known As
Robin D Cuzzort
Robin D Cuzzort is in his 60's
Robin Has Lived In
Columbia, SC
Springfield, IL
Madison, TN
Robin's Relatives
Robin D Cuzzort
Zodiac SignAquarius
Additional Infomation on Robin D Cuzzort
Robin D Cuzzort's Contact Information
Known Cities Lived In
Find out where Robin D Cuzzort has lived as well as Robin D Cuzzort's phone numbers and email addresses.
Robin D Cuzzort Has Lived in 4 States
South Carolina Address for Robin D Cuzzort
200 Axxxxx Wxx
Columbia SC
Columbia SC
Has Lived InGet Full Address Report
Columbia, SC
Springfield, IL (2 Addresses)
Phone Numbers Associated with Robin D Cuzzort
Get Full Phone Report
(816) ***-**** - Lees Summit, MO
(217) ***-**** - Buckley, IL
(615) ***-**** - Adams, TN
Email Address Associated with Robin D Cuzzort
Get Email Report
All trademarks, product names, company names or logos on this page are the property of their respective owners.
Related People Searches


text:
IMPORTANT: Please click "End Session" to clear your personal information. (Credit Card info is always hidden from view).End Session
Cookies are not enabled in your browser.
You must have Cookies enabled for the best experience on our site and to make a purchase.
Learn how to enable Cookies in your browser or call 1-800-426-8020 for assistance.
113 items
Women's Downlight® StormDown® Hooded Jacket$249.00-$269.00
Women's MicroTherm® StormDown® Hooded Jacket$229.00-$249.00
Women's Downlight® StormDown® Vest$149.00-$169.00
Women's Astoria Hooded Down Parka$199.00-$219.00
Women's Sandstone Soft Shell Jacket$99.00-$119.00 $69.30-$83.30
Women's Girl On The Go® Cropped Leggings$35.00-$40.00
Women's Girl On The Go® Knit Leggings$40.00-$45.00
Women's Cascadian Fleece Jacket$99.00-$119.00 $59.40-$71.40
Women's Slightly Curvy Washable Stretch Trousers$90.00-$99.00
Women's Passenger Ponte Skinny Pants$70.00-$80.00
Women's Slightly Curvy StayShape® Stretch Twill Trousers$70.00-$80.00
Women's Slightly Curvy StayShape® Stretch Twill Pants - Straight Leg$70.00-$99.00
Women's MicroTherm® StormDown® Field Jacket$229.00-$249.00
Women's Curvy Washable Stretch Trousers$90.00-$99.00
Women's Windfoil® Elite Soft Shell Trench$149.00-$169.00 $104.30-$118.30
Women's Curvy StayShape® Stretch Twill Trousers$70.00-$80.00
Women's Slope Side® Down Parka$229.00-$249.00
Women's Bremerton StayShape® Stretch Twill Pants$60.00-$80.00


text:
1 @Feralize;
2 @HilbertCressLover;
3 @Belarus.;
4 @Kakuna Matata;
5 @NfiNity;
6 @FinalArcadia;
7 @Bandit Keith;
8 @Greece;
9 @Exor;
10 @ghaskan;
11 @Lavender Frost;
12 @Hawkeye;
13 @Lithuania;
14 @DrumBeats;
16 @America*;
17 @GengarWithSunglasses;
18 @Umeko;
19 @Hitomi;
20 @jokool;
21 @Neonsands;
22 @Mijzelffan;
23 @Ryuutakeshi;
24 @harryheart;
25 @Tris79;
26 @Feliciano;
Nappa looked in the mirror as he flexed his muscles.
"What do you think of these bad boys," He spoke to him self. "Who's the strongest man alive? You are!"
He didn't hear the small army of penguins entered the door, he turned around.
"Hey there little guy" He said. "You lost?" he was shocked as the little thing jumped at him, he couldn't defend himself from the thing's claws and cuteness. Hi a few seconds he lay on the floor, no longer moving.
The next day, when everyone gathered in the plazas, to find out how was unlucky tonight. A while shape approached them.
"You're not getting rid of all of this goodness anytime soon! Nappa said.
You are Nappa
What are you doing here? Oh wait different bridge. You appear to help with the mood, and have died, but you're from the Dragon Ball world, and people come back to life all the time there.
Since you hang around after you've been killed, you can post after you have been killed, you may not vote, send or receive PM (unless the host sends them) or use QTs.
You are allied with the town, you win when all the mafia have been killed
Feliciano was killed she was allied with the town
It is now Day 2. You may now vote. This phase will end at 8:00 PM EST on July 21
NOTE: Even though Feliciano may still post in thread, she can not vote, or receive PMs, or post in Quick Topics. Breaking this rule will lead to a modkill. And no one wants that


text:
Lot 1: A Quantity of Pine Bedroom Furniture, to include a wardrobe, two chests of drawers and a bedside
A Quantity of Pine Bedroom Furniture, to include a wardrobe, two chests of drawers and a bedside locker. ...[more]
Create an account to customise your experience on the-saleroom.com
An email with a link to change your password, has been sent to your e-mail addressClose
Sorry, an error occured.Try again? Close
This auctioneer offers the-saleroom.com delivery service. We can collect, pack and deliver to your door.
The cost of delivery is shown in each lot description. The more lots you buy from this auction, the more you save on delivery.
View Delivery Pricing for information on buying multiple lots.
After the auction ends, you receive a delivery quote email for your consideration.
Delivery is scheduled to take place 7-10 working days after the final auction day, and we provide tracking information. Deliveries for large and special items (categories E, F, G and POA), and those outside the EU may take longer.
'Carriage liability' for loss or damage is limited to the lesser of the hammer value (including all auction premiums and VAT) or £150 per lot. You can purchase additional liability cover at a cost of 3% of the value over £150 and up to £3,000 per lot.
View our Frequently Asked Questions for further information.
Bidder Terms and Conditions apply to this service.
A subscription to the Price Guide is required to view results for auctions ten days or older. Click here for more information
A Quantity of Pine Bedroom Furniture, to include a wardrobe, two chests of drawers and a bedside locker. ...[more]
Taxidermy: A Male Pheasant. ...[more]
An Oil on Board Depicting The Interior of a Church, signed Roy Warwick and dated `79, along with a pair of modern furnishing prints. ...[more]
A White Glazed Wash Jug and Bowl, along with a pair of plaster figures of fireside dogs, a large figure of Our Lady, two mirrors and a box of assorted items to include a pair of twin handled vases. ...[more]
An Edwardian Mahogany and Inlaid Side Table, along with a light oak chest of three short drawers and a rectangular wall mirror. ...[more]
A Canon Camera and Case, and a `Pal` Meter. ...[more]
A Vintage Enamel Bread Bin and Cover. ...[more]
A 1950s Glazed Mahogany Bookcase with sliding doors. ...[more]
NO LOT. ...[more]
NO LOT. ...[more]
A Shelf of Sporting Interest Books to include a signed copy of Denis Law`s `The King`, also books on Pelé, A.P. McCoy, Eddie O`Sullivan & a couple of paperbacks to include Paddy`s Whiskey 100 Great Sporting Moments. ...[more]
A Quantity of Die Cast Vehicles to include Lledo Days Gone By. (19) ...[more]
A Quantity of Floral Decorated Door Fittings, handles etc. ...[more]
A Shelf of Decorative Items including miniature `Sestral` barometer and clock. ...[more]
Two Office Chairs, with leather effect upholstery. ...[more]
A Quantity of Assorted Pictures and Prints. ...[more]
A Box of Assorted Plated and Metalwares, to include candelabrum, a teapot, etc. ...[more]
An Oak Bureau, having fall-flap upper section revealing fitted interior, above shelved section. ...[more]
A Coloured Print of a Still life of Flowers in a Vase, along with another floral still life and a needlepoint example. ...[more]
A Mixed Lot to Include an Aladdin Oil Lamp, decanter, platter, comport, etc. ...[more]
An Ab Rolling Machine and a Step Aerobics Machine. ...[more]
A Oak Refectory Table, Three Ladder-Back Chairs, and a Modern Rug. ...[more]
Two Oils on Canvas, one a modern example depicting seagulls flying over choppy seas at night, the other a house in landscape. ...[more]
A Gents Raleigh Bicycle, along with lock and key. ...[more]
A Ladies Gola Panache Bicycle, along with lock and key. ...[more]
A Reproduction French Advertising Poster. ...[more]
A Monochrome Engraving, `Vue de Tivoli` ...[more]
An Ebony Overmantel Mirror. ...[more]
A Set of Four Coloured Prints, Views of 19th Century Hong Kong. ...[more]
A Quantity of Assorted Pictures and Prints. ...[more]
Two Hand Saws. ...[more]
A Shiela Sanford Print. ...[more]
Four Vintage Suitcases and a Metal Filing Box. ...[more]
Two Late 19th Century Beech Hoop-Back Windsor Chairs. ...[more]
An Oil on Canvas depicting seagulls flying over choppy seas (x 1) ...[more]
A Pair of Limited Edition Prints after Rossetti, a portrait print of a happy couple entitled `his Favourite` a coloured print depicting two alter boys outside a church entitled `Feeding the pigeon` and three small coloured prints held in one frame, (5). ...[more]
A Quantity of Fishing Rods including Wychwood. ...[more]
A Chrome Uplighter and a Three Division Wicker room Screen. ...[more]
A Quantity of Assorted Gardening Tools, to include, clippers, rake, fork, etc. ...[more]
Three 20th Century Folding Card Tables. ...[more]
A Pair of Oars, (one af) ...[more]
A Pair of Pine Single Beds. ...[more]
A `Vitra` Low Level Pan and Cistern. ...[more]
A Hotpoint Condenser Dryer and a Whirlpool Washing Machine. ...[more]
A Blue Ladies Bicycle. ...[more]
A Quantity of Gardening Tools, to include brushed, rake, spade, etc. ...[more]
A Wall Hanging Corner Cabinet, having leaded astragal glazed doors. ...[more]
A White Chest of Drawers With Mirror, along with a two tier oak table and an inlaid bedside cabinet. ...[more]
A Coloured Print of Figures and Animals in a Mountain Landscape, a large floral furnishing print, an `Elvis Presley` mirror, a framed and glazed map and four others. ...[more]
A Quantity of Assorted Dinner and Tea Wares, with green border and gilt decoration. ...[more]
A Vintage Junior Lister Engine, 3 horse power. ...[more]
A Quantity of Furniture for Restoration, a small oak open bookcase, a piano stool, a wash stand, a rectangular wall mirror, etc. ...[more]
A Vintage `Petters` Engine, 1.5 horse power. ...[more]
An Early 19th Century Breakfront Bookcase, and a Plinth Base, in need of restoration. ...[more]
Two Vintage Lavatory Bowls. ...[more]
A Stair Lift. ...[more]
An Outboard Motor Selva 400 Sport. ...[more]
A Set of Four Suede Effect Covered Chairs, along with a pine TV cabinet and a sofa table. ...[more]
A Treadle Sewing Machine, with interior fitted machine intact ...[more]
Three Jewellery Stands in the Form of Busts, along with three soft toys. ...[more]


text:
301 Views
By Revision3
406 Views
4,251 Views
How to Install Photoshop CS5 (Extended Edition)
467 Views
Adobe CS5 Master Collection - Installation Guid...
15,105 Views
13 Views
By techyv11
Adobe Photoshop CS5 Release Download
217 Views
By tmb052
Adobe Photoshop CS5 (Mac) (Old Version)
10 Views
Adobe Photoshop CS5 (Old Version)
48 Views
Adobe Photoshop CS5 (Mac) (Old Version)
24 Views
Adobe Premiere Pro CS5 FINAL Www.irsofts.com
479 Views
Adobe Photoshop CS5 - PatchMatch - Www.CS5.org
10,129 Views
By: Metacafe Affiliate U
Sneak Peek of New Adobe Photoshop CS5 Technolog...
2,815 Views
By: Metacafe Affiliate U
Adobe Photoshop CS5 - Spot Healing and Fill Too...
3,307 Views
By: Metacafe Affiliate U
Photoshop CS5: 3D Text in Photoshop CS5 Extended
2,068 Views
By: Metacafe Affiliate U
Adobe Premiere Pro CS5 - Mercury Playback Engin...
1,107 Views
By: Metacafe Affiliate U
Adobe Photoshop CS5 Content-Aware Fill Sneak Peek
1,804 Views
By: Metacafe Affiliate U
Adobe Photoshop CS5: Puppet Warp Sneak Peek
4,151 Views
By: Metacafe Affiliate U
Exporting DVD from Lynda.com: Encore CS5 Essent...
33 Views
By: Metacafe Affiliate U
4,336 Views
By: Metacafe Affiliate U
Adobe Photoshop CS5 - Content-Aware Fill
3,992 Views
By: Metacafe Affiliate U
Photoshop CS5 Tutorial. How to Design a Thanksg...
37 Views
By WPThemes
PhotoShop CS5 Tutorial, Tricks, EBook PDF Free...
235 Views
By johncarivac
PhotoShop CS5 Tutorial, Tricks, EBook PDF Free...
506 Views
By johncarivac
Lynda.com Adobe Dreamweaver CS5 New Features DVD
257 Views
Adobe Photoshop CS5 Free Download-Full Version...
34,529 Views
Adobe Photoshop CS5 - Painting Sneak Peek
1,391 Views
By: Metacafe Affiliate U
Adobe Illustrator CS5-Perspective Drawing
214 Views
By: Metacafe Affiliate U
Adobe Photoshop CS5 Portable - FREE DOWNLOAD
669 Views
By marktomsoon
Photoshop CS5 Tutorial - Trabalhando Com Black&...
66 Views
Adobe CS5 for MAC FREE DOWNLOAD
1,395 Views
By kejsok93
Download Photoshop CS5: http://fileups.net/2h4nd
Download Keygen: http://filesmy.com/2hT595
Additional Serials: http://fileups.net/2h4nC
Top new features of Photoshop CS5 and Photoshop CS5 Extended:
Intelligent selection technology
Photoshop CS5 takes the time and frustration out of making precise image selections and masks, providing you a faster way to extract subjects from their backgrounds and create realistic composites. New intelligent selection technology offers better edge detection and faster, more accurate masking results of complex subjects, like hair. Automatic color decontamination helps you eliminate background color around the edges of a selection, resulting in more seamless compositions when placing extracted subjects on new backgrounds.
Experienced Photoshop users know that the best
selections are created by constantly adapting the selection technique for differences in the subject's edges--one method for hair and another for the edge of a building. With Photoshop CS5, you can produce highly accurate masks and selections faster and more simply than before with a set of new adaptive selection-edge modification controls. Smart Radius automatically matches the best selection approach with the subject's changing edge characteristics, and the extra view modes assist you in previewing the quality of your selections. The Refine Radius and Erase Refinements tools customize your masks and selections as you make them. These tools, in combination with the color decontamination settings, help eliminate any residual background color from around the edges of your selections.
HDR Pro for creativity and precision with the next generation of high dynamic range imaging
Faster performance with cross-platform native 64-bit support
Easier interface management with Live Workspaces and Workspace Switcher
Mirror Links:
Download Photoshop CS5: http://goo.gl/pWuoZ
Download Keygen: http://goo.gl/LnXSX
Additional Serials: http://goo.gl/M6ZsC
~Adobe Photoshop CS5 Installation with Keygen~
~Adobe Photoshop CS5 Installation with Keygen~
~Adobe Photoshop CS5 Installation with Keygen~
Commonly Encountered Problems:
1. I am Getting "Insert Photoshop CS5 Disk To Continue" Error while Installing Photoshop.
Solution: Don't Install Photoshop from a cd or usb drive. Install it from the hard disk.
2. I am Getting "Invalid Serial Number" each time I open Photoshop.
Solution: Use The Link Given Above (Additional Serials)
3. Your Keygen Has Virus. My antivirus is blocking/deleting it.
Solution: The Keygen is completely clean. You Can use it safely by turning off your antivirus. But still if you don't trust it, use a key from the file http://fileups.net/2h4nC
4. Can I Update my photoshop?
And: yes, you can update it.
Feel free to aks if you have any other problems.
It took a lot of effort to upload this. A simple Thanks or Suscribe is expected!
Adobe Photoshop CS5 installation
Adobe Photoshop CS5 installation
Adobe Photoshop CS5 installation
Adobe Photoshop CS5 installation
Adobe Photoshop CS5 installation
Extra tags:photoshop cs5 photoshop cs5 tutorials photoshop cs5 trial photoshop cs5 tutorial photoshop cs5 release date photoshop cs5 serial number photoshop cs5 upgrade how to use photoshop cs5 photoshop cs5 features photoshop cs5 video photoshop cs5 keygen photoshop cs5 price photoshop cs5 extended photoshop cs5 training buy photoshop cs5 photoshop cs5 free download photoshop cs5 beta photoshop cs5 download photoshop cs5 new features photoshop cs5 crack free photoshop cs5 download photoshop cs5 student photoshop cs5 student edition photoshop cs5 wiki photoshop cs5 free trial serial number for photoshop cs5 photoshop cs5 plugins photoshop cs5 review photoshop cs5 videosphotoshop cs5 release photoshop cs5 trial download photoshop cs5 brushes photoshop cs5 download free photoshop cs5 upgrade price cheap photoshop cs5 photoshop cs5 youtube photoshop cs5 beta download how much is photoshop cs5 download photoshop cs5 free photoshop cs5 student discount photoshop cs5 free .....


text:
Microsoft has been around for a long time. It's had its share of hits, and flops.
We're taking a looking at some of its biggest mistakes here.
Proof you can't get everything right.
There are hundreds of thousands of sensors in the ocean—here's why
More "Industry IQ" »
Understand this one thing to have a successful digital business
More "Digital Business Decoded" »
A financial planner says there's something everyone should do before trying to get rich
More "World 2.0" »


text:
A small metal saw cutting through an iron rod. Equipment used: Zoom H6 - XY stereo mic.
Ambient hammering and movement from the metal workshop.
Rain stick sample
glasses cheering
Street market on the Helvetiaplatz in Zurich
Short recording of a crowded place. Captured with Zoom H2.
Recorded a little low, using an olympus field recorder.
A stereo field recording of woodcarving, where the carver chops out a piece of Ash (Fraxinus excelsior) with a gouge ...
Spot effects recorded in a recreation of a saddle maker's workshop circa 1850. Includes stitching, creasing and cutting leather with ...
Various sounds recorded in a traditional blacksmith's workshop. Furnace can be heard in the background. Includes hammering a horse shoe ...
small clap like a golf clap or small crowd.
Hitting knives against other knives
Hitting knives again brick to make the sound of a sword fight
machete machete sword fight far metal metallic collision free
machete fight hit sword metallic metal free


text:
A group of U.S. Senators on the West Coast have introduced a bill Wednesday aiming to prohibit offshore drilling on the outer continental shelf of California, Oregon and Washington.
The Danish-South Korean Green Growth Alliance met for roundtable talks yesterday. The Minister for Business and Growth's meeting with the South Korean Minister
Offshore rig driller Seadrill is facing another two years in the doldrums but hopes the international rig market could turn around in 2017.
Rig rates have more
China's Foreign Ministry said on Friday it was against parties entering territorial waters in the name of freedom of navigation, as the United States is considering
The fully integrated platform management system Servowatch designed and built for three new offshore patrol vessels for the U.K. Royal Navy has completed BAE Systems' Factory Acceptance Tests (FAT).
Construction has begun on a new warship for the U.K. Royal Navy as the Minister of State for Defense Procurement, Philip Dunne MP cut the first steel in Glasgow today.


text:
Are you Ryota Kawase?Claim your profile
Publications (27)82.02 Total impact
Article: Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice[Show abstract] [Hide abstract]
ABSTRACT: A close correlation between atherosclerosis, inflammation, and osteoporosis has been recognized, although the precise mechanism remains unclear. The growth factor progranulin (PGRN) is expressed in various cells such as macrophages, leukocytes, and chondrocytes. PGRN plays critical roles in a variety of diseases, such as atherosclerosis and arthritis by inhibiting Tumor Necrosis Factor-α (TNF-α) signaling. The purpose of this study was to investigate the effect of PGRN on bone metabolism. Forty-eight-week old female homozygous PGRN knockout mice (PGRN-KO) (n=8) demonstrated severe low bone mass in the distal femur compared to age- and sex-matched wild type C57BL/6J mice (WT) (n=8) [BV/TV (%): 5.8 vs. 16.6; p<0.001, trabecular number (1/mm): 1.6 vs. 3.8; p<0.001]. In vitro, PGRN inhibited TNF-α-induced osteoclastogenesis from spleen cells of PGRN-KO mice (vehicle→5→50 ng/ml PGRN: 172.3→138.0→132.0 number of osteoclasts per six fields; vehicle vs. 50 ng/ml, p<0.05). Moreover, PGRN significantly promoted ALP activity (vehicle→5→50 ng/ml PGRN: 28.1→36.5→51.7 ALP/protein units/μg protein; vehicle vs. 50 ng/ml, p<0.05), osteoblast-related mRNA (ALP, osteocalcin) expression in a dose-dependent manner and up-regulated osteoblastic differentiation by down-regulating phosphorylation of ERK1/2 in mouse calvarial cells. In conclusion, PGRN may be a promising treatment target for both atherosclerosis and inflammation-related osteoporosis. Copyright © 2015. Published by Elsevier Inc.Biochemical and Biophysical Research Communications 08/2015; 465(3). DOI:10.1016/j.bbrc.2015.08.077 · 2.30 Impact Factor
Article: Myocardial Energy Provision Is Preserved by Increased Utilization of Glucose and Ketone Bodies in CD36 Knockout Mice[Show abstract] [Hide abstract]
ABSTRACT: CD36 is an important transporter of long-chain fatty acids (LCFAs) in the myocardium. As we have reported previously, CD36-deficient patients demonstrate a marked reduction in myocardial uptake of (123)I-15-(p-iodophenyl)-(R, S)-methyl pentadecanoic acid (BMIPP), which is an analog of LCFAs, while myocardial (18)F-fluorodeoxy-glucose (FDG) uptake is increased. However, it has not been clarified whether energy provision is preserved in patients with CD36 deficiency. The aims of the current study were to investigate the myocardial uptake of glucose and alterations in myocardial metabolites in wild-type (WT) and CD36 knockout (KO) mice. High-resolution positron emission tomography (PET) demonstrated markedly enhanced glucose uptake in KO mouse hearts compared with those of WT mice in real-time. The myocardial protein expression of glucose transporter protein 1 (GLUT1) was significantly enhanced in KO mice compared to WT mice, whereas that of GLUT4 was not altered. While the myocardial expression of genes involved in fatty acid metabolism did not increase in KO mice, that of genes related to glucose utilization compensatorily increased in KO mice. The metabolomic analysis of cardiac tissues revealed that the myocardial concentrations of ATP and phosphocreatine were maintained, even in KO mice. The concentration of 3-hydroxybutyric acid and mRNA expression of hydroxybutyrate dehydrogenase in the heart were significantly higher in KO than in WT mice. These data suggest that high-energy phosphate might be preserved by the increased utilization of glucose and ketone bodies in CD36KO mouse hearts under conditions of deficient LCFA uptake. Copyright © 2015. Published by Elsevier Inc.Metabolism 06/2015; 64(9). DOI:10.1016/j.metabol.2015.05.017 · 3.89 Impact Factor
- Atherosclerosis 08/2014; 235(2):e104-e105. DOI:10.1016/j.atherosclerosis.2014.05.281 · 3.99 Impact Factor
Article: A novel potent and selective pparalpha agonist, k-877, ameriolates both fasting and postprandial hypertriglyceridemiaAtherosclerosis 08/2014; 235(2):e169-e170. DOI:10.1016/j.atherosclerosis.2014.05.490 · 3.99 Impact Factor
Article: Correction: Establishment of a Novel Murine Model of Ischemic Cardiomyopathy with Multiple Diffuse Coronary Lesions[Show abstract] [Hide abstract]
ABSTRACT: [This corrects the article on p. e70755 in vol. 8.].PLoS ONE 08/2013; 8(8). DOI:10.1371/annotation/8d40f661-efc4-4590-8922-b3a6f5374e12 · 3.23 Impact Factor
Article: Establishment of a Novel Murine Model of Ischemic Cardiomyopathy with Multiple Diffuse Coronary Lesions[Show abstract] [Hide abstract]
ABSTRACT: Atherosclerotic lesions of the coronary arteries are the pathological basis for myocardial infarction and ischemic cardiomyopathy. Progression of heart failure after myocardial infarction is associated with cardiac remodeling, which has been studied by means of coronary ligation in mice. However, this ligation model requires excellent techniques. Recently, a new murine model, HypoE mouse was reported to exhibit atherogenic Paigen diet-induced coronary atherosclerosis and myocardial infarction; however, the HypoE mice died too early to make possible investigation of cardiac remodeling. Therefore, we aimed to modify the HypoE mouse model to establish a novel model for ischemic cardiomyopathy caused by atherosclerotic lesions, which the ligation model does not exhibit. In our study, the sustained Paigen diet for the HypoE mice was shortened to 7 or 10 days, allowing the mice to survive longer. The 7-day Paigen diet intervention starting when the mice were 8 weeks old was adequate to permit the mice to survive myocardial infarction. Our murine model, called the "modified HypoE mouse", was maintained until 8 weeks, with a median survival period of 36 days, after the dietary intervention (male, n = 222). Echocardiography demonstrated that the fractional shortening 2 weeks after the Paigen diet (n = 14) significantly decreased compared with that just before the Paigen diet (n = 6) (31.4±11.9% vs. 54.4±2.6%, respectively, P<0.01). Coronary angiography revealed multiple diffuse lesions. Cardiac remodeling and fibrosis were identified by serial analyses of cardiac morphological features and mRNA expression levels in tissue factors such as MMP-2, MMP-9, TIMP-1, collagen-1, and TGF-β. Modified HypoE mice are a suitable model for ischemic cardiomyopathy with multiple diffuse lesions and may be considered as a novel and convenient model for investigations of cardiac remodeling on a highly atherogenic background.PLoS ONE 08/2013; 8(8):e70755. DOI:10.1371/journal.pone.0070755 · 3.23 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Progranulin (PGRN) is a multifunctional protein known to be involved in inflammation. However, the relation between PGRN and atherosclerosis remains elusive. The aim of this study was to define the role of PGRN in the development of atherosclerosis.Methods and ResultsFirst, we checked the expression levels of PGRN in human atherosclerotic plaques. Immunohistochemical analysis showed that PGRN is strongly expressed in foam cells of atherosclerotic plaques. We also found that PGRN is expressed more abundantly in macrophages than in the smooth muscle cells of atherosclerotic lesions in ApoE(-/-) mice fed a high-fat diet for 12 weeks. Next, PGRN(-/-)ApoE(-/-) mice were generated to investigate the effect of PGRN on the development of atherosclerosis. PGRN(-/-)ApoE(-/-) mice exhibited severe atherosclerotic lesions compared to PGRN(+/+)ApoE(-/-) mice, despite their anti-atherogenic lipid profile. These results are partly due to enhanced expression of inflammatory cytokines, adhesion molecules, and decreased expression of endothelial nitric oxide synthase. In addition, lack of PGRN leads to accumulate excessive cholesterol in the macrophages and alter HDL-associated proteins. PGRN seems to be involved in the pathogenesis of atherosclerosis, possibly by various anti-atherogenic effects, including modulation of local and/or systemic inflammation.Cardiovascular Research 07/2013; 100(1). DOI:10.1093/cvr/cvt178 · 5.94 Impact Factor
Article: Apolipoprotein B-48 to Triglyceride Ratio Is a Novel and Useful Marker for Detection of Type III Hyperlipidemia after Antihyperlipidemic Intervention.[Show abstract] [Hide abstract]
ABSTRACT: Aim: Remnant lipoproteins are atherogenic and are accumulated in patients with type III hyperlipidemia (HL). Although type III HL is diagnosed by phenotyping apolipoprotein (apo) E, this procedure is time-consuming and inconvenient for routine clinical use. Clinical indices for screening type III HL in untreated HL patients have been proposed; however, in clinical settings, HL patients are promptly treated with lipid-lowering agents without diagnosing the underlying cause. We investigated whether existing clinical indices for screening type III HL as well as the apo B-48/triglyceride (TG) ratio, which was suggested to be related to the accumulation of small chylomicron (CM) remnants, are useful after the initiation of lipid-lowering therapies. Methods: In 25 normolipidemic subjects and 191 treated HL patients (type I, n =6; IIa, 62; IIb, 66; III, 12; IV, 22; and V, 23) from Osaka University Hospital and related hospitals, fasting low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), TG, and apolipoproteins were measured and clinical indices were evaluated statistically. Results: Apo B-48 levels were significantly higher in patients with type I, III, and V HL, and TG levels were significantly higher in patients with type I and V HL. The apo B-48/TG ratio was significantly higher only in patients with type III HL compared with other types of HL (p<0.001), and was statistically significant among the other clinical indices (AUC-ROC value, 0.895; cut-off value, 0.110). Conclusion: The apo B-48/TG ratio is a novel and useful marker for detecting type III HL even after the initiation of lipid-lowering interventions.Journal of atherosclerosis and thrombosis 08/2012; 19(9):862-71. DOI:10.5551/jat.13052 · 2.73 Impact Factor
Article: Effect of Probucol on Antioxidant Properties of HDL in Patients with Heterozygous Familial Hypercholesterolemia[Show abstract] [Hide abstract]
ABSTRACT: High density lipoprotein (HDL) has multi-antiatherogenic effects such as antioxidation and anti-inflammation, in addition to being a key mediator of reverse cholesterol transport. Probucol, known as a lipid lowering drug, is also a potent antioxidant, but it decreases serum HDL cholesterol (HDL-C) levels. To elucidate the effect of probucol on antioxidant properties of HDL, we investigated the function of HDL derived from patients with heterozygous familial hypercholesterolemia (FH) who have been treated with probucol. Probucol-treated FH patients (n=21) showed a 47% reduction of serum HDL-C levels compared to probucol-untreated FH patients (n=15). High performance liquid chromatography (HPLC) analysis revealed that probucol diminished HDL particle size compared to the non-treated group. Antioxidant capacity of HDL was evaluated by its effect to protect reference LDL from oxidation induced in the presence of an oxidizing agent, AAPH. The HDL derived from the probucol-treated group demonstrated a significantly prolonged time to start oxidation by 112%, decreased the maximum oxidation rate by 14%, and lowered the maximum concentration of conjugated dienes formation by 15%. Furthermore, HDL-associated paraoxonase 1 (PON1) activity, but not platelet-activating factor acetyl-hydrolase (PAF-AH) correlated with these measurements of HDL anti-oxidative activity. Treatment with probucol in vitro and inhibition of PON1 activity demonstrated that probucol in HDL particles and increase of PON1 activity might largely contribute to the increase of HDL anti-oxidative activity. Probucol reduced HDL-C levels and HDL particle size in patients with heterozygous FH, while it concomitantly enhanced HDL anti-oxidative properties, possibly through increasing PON1 activity.Journal of atherosclerosis and thrombosis 07/2012; 19(7):643-56. DOI:10.5551/jat.12807 · 2.73 Impact Factor
Article: Serum adiponectin level is correlated with the size of HDL and LDL particles determined by high performance liquid chromatography[Show abstract] [Hide abstract]
ABSTRACT: Objective: Adiponectin (APN) improves insulin resistance and prevents atherosclerosis, and HDL removes cholesterol from atherosclerotic lesions. We have demonstrated that serum HDL-cholesterol (HDL-C) and APN concentrations are positively correlated and that APN accelerates reverse cholesterol transport (RCT) by increasing HDL synthesis in the liver and cholesterol efflux from macrophages. We previously reported that APN reduced apolipoprotein (apo) B secretion from the liver. It is well-known that insulin resistance influences the lipoprotein profile. In this study, we investigated the clinical significance of APN levels and insulin resistance in lipoprotein metabolism. Material/method: We investigated the correlation between serum APN concentration, HOMA-R, the lipid concentrations and lipoprotein particle size by high-performance liquid chromatography (HPLC) in 245 Japanese men during an annual health checkup. Results: Serum APN level was positively correlated with the cholesterol content in large LDL and HDL particles, but inversely correlated with the cholesterol content in large VLDL and small LDL particles. HOMA-R was negatively correlated with the cholesterol content in large LDL and HDL particles and positively correlated with the cholesterol content in large VLDL and small LDL particles. By multivariate analysis, APN was correlated with the particle size of LDL-C and HDL-C independently of age, BMI and HOMA-R. Conclusions: APN may be associated with the formation of both HDL and LDL particles, reflecting the enhancement of RCT and the improvement in TG-rich lipoprotein metabolism and insulin resistance.Metabolism: clinical and experimental 06/2012; 61(12). DOI:10.1016/j.metabol.2012.05.011 · 3.89 Impact Factor
Article: Patients with CD36 Deficiency Are Associated with Enhanced Atherosclerotic Cardiovascular Diseases[Show abstract] [Hide abstract]
ABSTRACT: The clustering of dyslipidemia, impaired glucose tolerance and hypertension increases the morbidity and mortality from cardiovascular events. A class B scavenger receptor, CD36, is a receptor for oxidized LDL and a transporter of long-chain fatty acids. Because of the impaired uptake of oxidized LDL in CD36-deficient macrophages and from the results of CD36 knockout mice, CD36 deficiency (CD36-D) was supposed to be associated with reduced risks for coronary artery disease (CAD); however, CD36-D patients are often accompanied by a clustering of coronary risk factors. The current study aimed to investigate the morbidity and severity of cardiovascular diseases in CD36-D patients. By screening for CD36 antigen on platelets and monocytes using FACS or the absent myocardial accumulation of 123I-BMIPP by scintigraphy, 40 patients with type I CD36-D were collected, the morbidity of CAD and their features of atherosclerotic cardiovascular diseases were observed. Screening for CD36-D in both CAD patients (n = 319) and healthy subjects (n = 1,239) were underwent. The morbidity of CAD was significantly higher in CD36-D patients than in the general population; 50% of patients (20 out of 40) had CAD identified by BMIPP scintigraphy and 37.5% (3 out of 8) by FACS screening, respectively. Three representative CD36-D cases demonstrated severe CAD and atherosclerosis. The frequency of CD36-D was three times higher in CAD patients than in healthy subjects (0.9% vs 0.3%, p < 0.0001). The morbidity of CAD is significantly higher in CD36-D patients suffering from severe atherosclerosis, implying that the status of CD36-D might be atherogenic.Journal of atherosclerosis and thrombosis 11/2011; 19(3):263-75. DOI:10.5551/jat.10603 · 2.73 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Postprandial hyperlipidemia (PH) is thought to be caused by the impaired postprandial metabolism of triglycerides (TG)-rich lipoproteins in both endogenous and exogenous pathways; however, there is no consensus. It is difficult to estimate the presence of PH without performing a time-consuming oral fat loading (OFL) test, so postprandial lipoprotein metabolism was analyzed by measuring the postprandial levels of apolipoprotein (apo) B-48 and apo B-100, and the correlation between postprandial TG increase and fasting apoB-48 levels was assessed to establish a good marker of PH without performing an OFL test. Ten male normolipidemic subjects were loaded with a high-fat (HF, 1045 kcal) or standard (ST, 566 kcal) meal, and the lipids, apolipoproteins and lipoprotein profiles were analyzed after each meal. TG, apo B-48, remnant-like particles (RLP)-cholesterol and RLP-TG levels were increased and their levels were significantly higher after intake of the HF meal than the ST meal; however, there was no postprandial increase in apo B-100 and LDL-C levels. Postprandial increases in TG levels of CM, VLDL, LDL and HDL were significantly higher after intake of the HF meal than the ST meal. Fasting apo B-48 levels were strongly correlated with the incremental area under the curve of TG after intake of the HF meal, but not the ST meal. Postprandial TG increase was mainly due to increased CM and CM-R, but not VLDL. Measurement of fasting serum apo B-48 may be a simple and useful method for assessment of the existence of PH.Journal of atherosclerosis and thrombosis 09/2011; 18(12):1062-70. DOI:10.5551/jat.10470 · 2.73 Impact Factor
Article: Establishment of chemiluminescence enzyme immunoassay for apolipoprotein B-48 and its clinical applications for evaluation of impaired chylomicron remnant metabolism[Show abstract] [Hide abstract]
ABSTRACT: Apolipoprotein B-48 (apoB-48) is a constituent of chylomicron remnants synthesized in the small intestines. The serum concentration of apoB-48 at fasting has been reported to be a marker of postprandial hyperlipidemia, a presumed risk factor for atherosclerosis. We evaluated the basal performance of a recently developed chemiluminescent enzyme immunoassay (CLEIA). We also examined the correlations between serum apoB-48 concentrations and other lipid concentrations or life style patterns, including smoking and drinking. We analyzed the data of 273 clinical samples by multiple regression analysis to examine the influence of other serum lipid values, age, sex, smoking, drinking status and BMI on serum apoB-48 values. Within-run and between-run precision was obtained with 1.7-2.7% and 1.2-7.3%, respectively. The correlativity of enzyme-linked immunosorbent assay was correlation coefficient r=0.953, and regression y=1.02×-1.59. Serum apoB-48 concentrations were higher in males than in females, and were correlated with the status of smoking as well as with remnant-like particle-cholesterol (RLP-C) concentrations. Patients with the metabolic syndrome showed higher values of serum apoB-48 compared with control subjects. Serum apoB-48 measurement by CLEIA was satisfactory for clinical use to assess abnormalities in the chylomicron remnant metabolism.Clinica chimica acta; international journal of clinical chemistry 09/2011; 413(1-2):160-5. DOI:10.1016/j.cca.2011.09.013 · 2.82 Impact Factor
Article: Serum apolipoprotein B-48 levels are correlated with carotid intima-media thickness in subjects with normal serum triglyceride levels[Show abstract] [Hide abstract]
ABSTRACT: Postprandial hyperlipidemia (PPHL) is an independent risk factor for coronary heart disease (CHD) which is based on the accumulation of chylomicrons (CM) and CM remnants containing apolipoprotein B-48 (apoB-48). Since atherosclerotic cardiovascular diseases are frequently observed even in subjects with normal serum triglyceride (TG) level, the correlation between fasting apoB-48 containing lipoproteins and carotid intima-media thickness (IMT) was analyzed in subjects with normal TG levels. From subjects who took their annual health check at the Osaka Police Hospital (n=245, male), one-hundred and sixty-four male subjects were selected to take part in this study; the excluding factors were: systolic blood pressure ≥ 140 mmHg, intake of antihypertensive or antihyperlipidemic drugs, or age >65 years. The association between biochemical markers and IMT was analyzed and independent predictors of max-IMT were determined by multiple regression analysis in all subjects and in groups N-1 (TG<100mg/dl, n=58), N-2 (100 ≤ TG<150 mg/dl, n=53) and H (150 ≤ TG mg/dl, n=53), respectively. Fasting total cholesterol, LDL-cholesterol, HDL-cholesterol, apoB-100 and lnRemL-C (remnant lipoprotein-cholesterol) levels were not correlated with max-IMT, but lnTG and lnapoB-48 were significantly correlated with max-IMT in all subjects. LnapoB-48 and apoB-48/TG ratio were significantly correlated with max-IMT in group N-2. By multiple regression analysis, age and lnapoB-48 were independent variables associated with max-IMT in group N-2. Serum apoB-48 level might be a good marker for the detection of early atherosclerosis in middle-aged subjects with normal-range levels of blood pressure and TG.Atherosclerosis 05/2011; 218(1):226-32. DOI:10.1016/j.atherosclerosis.2011.05.009 · 3.99 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Postprandial hypertriglyceridemia (PHTG) has been shown repeatedly to be associated with metabolic syndrome and atherosclerotic cardiovascular diseases. We have recently reported that ezetimibe inhibits PHTG in patients with type IIb hyperlipidemia. Ezetimibe was also reported to atten-uate PHTG in combination with low-dose statins in patients with obesity or metabolic syndrome. We reported CD36-deficient (CD36KO) mice as a new model for PHTG, in which the synthesis of chylomicron (CM) in the small intestines is enhanced. In the current study, we investigated the effect of ezetimibe on PHTG in this mouse model of metabolic syndrome. Wild-type (WT) mice fed a western diet, and CD36KO mice fed a normal chow diet, respectively, were treated for 3 weeks with and without ezetimibe, followed by an evaluation of triglyceride (TG) concentrations by enzymatic method and by high performance liquid chromatogra-phy (HPLC) as well as those of and apolipoprotein (Apo) B-48 in plasma and intestinal lymph after oral fat loading with olive oil. Intestinal mucosa was also harvested to evaluate the transcriptional regulation of the genes involved in the intestinal production of ApoB-containing lipoproteins. Ezetimibe dramatically reduced PHTG in both WT and CD36KO mice. HPLC analysis of plasma showed that the decrease in TG content in CM and CM remnants-sized particles contributed to this suppression, suggesting that CM production in the small intestines might be reduced after ezetimibe treatment. Intestinal lymph was collected after oral fat loading in ezetimibe-treated and non-treated mice. Both TG content and ApoB-48 mass were decreased in ezetimibe-treated mice. The quantitative RT-PCR of intestinal mucosa showed down-regulation of the mRNA expression of FATP4 and ApoB in both groups along with FABP2, DGAT1, DGAT2 and SCD1 in WT mice at postprandial state after ezetimibe treatment. Ezetimibe alone reduces PHTG by blocking both the absorption of cholesterol and the intracellular trafficking and metabolism of long-chain fatty acids in enterocytes, resulting in the reduction of the formation of ApoB-48 which is necessary for the ApoB48-containing lipoprotein production in the small intestines.Journal of atherosclerosis and thrombosis 09/2010; 17(9):914-24. DOI:10.5551/jat.4929 · 2.73 Impact Factor
Article: MS54 SERUM APOLIPOPROTEIN B48 LEVEL IS CORRELATED WITH CAROTID INTIMA-MEDIA THICKNESS (IMT) IN SUBJECTS WITH NORMAL SERUM TRIGLYCERIDE LEVELAtherosclerosis Supplements 06/2010; 11(2):121-121. DOI:10.1016/S1567-5688(10)70555-9 · 2.29 Impact Factor
Article: Adiponectin enhances de novo hepatic HDL synthesis through LXR alpha-and COUP-TFII-dependent pathwaysAtherosclerosis Supplements 06/2010; 11(2):79-79. DOI:10.1016/S1567-5688(10)70361-5 · 2.29 Impact Factor
Article: P354 A NOVEL HDL-ASSOCIATED PROTEIN, PROGRANULIN, IS INVOLVED IN LIPID METABOLISM AND MACROPHAGE RECRUITMENT INTO ADIPOSE TISSUESAtherosclerosis Supplements 06/2010; 11(2):92-92. DOI:10.1016/S1567-5688(10)70421-9 · 2.29 Impact Factor
Article: P300 EFFECT OF PROBUCOL ON AN ANTIOXIDANT PROPERTY OF HDL IN PATIENTS WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIAAtherosclerosis Supplements 06/2010; 11(2):80-81. DOI:10.1016/S1567-5688(10)70367-6 · 2.29 Impact Factor
Article: P343 FATTY ACIDS DERIVATIVES BY LIPID PEROXIDATION ARE SIGNIFICANTLY INCREASED IN PATIENTS WITH HIGH APOLIPOPROTEIN B48 LEVELS, INDEPENDENT OF TRIGLYCERIDE CONCENTRATIONSAtherosclerosis Supplements 06/2010; 11(2):89-89. DOI:10.1016/S1567-5688(10)70410-4 · 2.29 Impact Factor
Top Journals
Osaka UniversitySuika, Ōsaka, Japan
Osaka City University
Ōsaka, Ōsaka, Japan
- Department of Cardiovascular Medicine
Kawasaki Saiwai HospitalKawasaki, Fukuoka, Japan
University of Texas at DallasRichardson, Texas, United States