text:
Image Unavailable
- Sorry, this item is not available in
- Image not available
- To view this video download Flash Player
|Additional DVD options
Amazon Price
|New from
|Used from
(Jun 15, 2010)
"Please retry"
|Watch Instantly with
Fulfillment by Amazon (FBA) is a service we offer sellers that lets them store their products in Amazon's fulfillment centers, and we directly pack, ship, and provide customer service for these products. Something we hope you'll especially enjoy: FBA items qualify for FREE Shipping and .
If you're a seller, Fulfillment by Amazon can help you increase your sales. We invite you to learn more about Fulfillment by Amazon .
Jayne (Parker Posey) and Laura (Demi Moore) are about to take on the first man they just might not be able to handle: their father Joe (Rip Torn). Dutiful daughters returning to the house they grew up in, Jayne and Laura are forced to take a closer look at their own not-so-perfect lives. Laura suspects that Joe needs full-time care, but Jayne refuses to believe that their father's condition is serious. Jayne's compulsion to escape reality only increases Laura's attempts to yank her back down to earth. Meanwhile, Joe still sings and plays the blues on his prized guitar, and the lively widower even has a new "ladyfriend," shameless and sassy Shelly (Ellen Barkin). Tensions flare as Joe's senility increases and the close sisters must also juggle their own very different lives – but their adventures back home are not without merriment, mischief and even a little childhood magic.
Parker Posey and Demi Moore prove inspired casting as troubled sisters in Happy Tears. Posey (all quirks and neuroses) plays Jayne, the sister who married the wealthy but unstable son of a famous artist and is now enveloped in a bubble of money; Moore (half woman warrior, half earth mother) plays Laura, the sister who isn't rich and who has ended up taking care of their increasingly erratic father, Joe (Rip Torn, Men in Black, The Larry Sanders Show), and who is managing--just barely--not to resent Jayne for the difference in their lives. But Joe is slipping into dementia and giving away money to a needy addict named Shelly (Ellen Barkin, Ocean's Thirteen, Sea of Love), so Jayne comes back home to decide with Laura what to do. Happy Tears is a peculiar yet vivid movie; the naturalistic surface of its domestic drama is punctured with odd moments of surrealism, such as when Jayne hallucinates that a boot salesman has turned into a vulture. The plot wanders, the characters are explored unevenly, yet moment to moment Happy Tears holds you by virtue of a surprising honesty. Jayne, Laura, Joe, and Shelly feel--despite a bit of hamminess in the performances--like real people, with jagged edges that can't be ignored or explained away. --Bret Fetzer
Stills from Happy Tears (Click for larger image)
Product Details
Would you like to update product info or give feedback on images?
Probably one of the worst movies I've ever seen......I actually thru it away!!! Sorry I had to give it any star!Published 15 months ago by PGM
Another example of the trailers being the best parts of the movie. Well written, well cast, well acted but the dream sequences broke up the flow of the movie and added nothing.Published on August 24, 2013 by Ricardo
Portrayal of two fortyish sisters struggling with immature, selfish father and husbands. The old man has dementia and cannot be left alone with his crackhead "nurse" anymore. Read morePublished on March 18, 2013 by mr. contrarian


text:
The members of VonAmp said they had a great time at Webster Hall because they were finally able to meet a lot of the East Coast performers that they've been admiring (and messaging) on YouTube. The band said Mr. Salottolo, founder of the Youth Arts Forum, was extremely gracious and kind. When VonAmp stepped up to do their sound check and threw in a song, he smiled big and said, "You sound EXACTLY how I knew you would!" After VonAmp performed its segment of the show, Mr. Salottolo asked the band if they would be interested in being one of the headliners in his East Coast touring circuit. (Mr. Salottolo appears with VonAmp in the lower-right corner of our photo montage above.)
The concert dubbed, "Kids Helping Kids" was held in the portion of Webster Hall called The Studio which carries on the legacy of the 1950s and 60s when Webster Hall became the live recording home of RCA Records, and where legends such as Elvis Presley, Sam Cooke, Ray Charles and Bob Dylan made rock and roll history.
Before returning home, VonAmp and its entourage took to the streets of New York City. According to VonAmp's drummer, Nik Scarpaci, "We dined at so many restaurants while we were there and the food was phenomenal!"
The bass guitarist and lead guitarist brothers, Collin and Taylor Barrett agreed on one thing, "The people of New York are polite, friendly, and they really made us feel at home in their city."
The band also made their way to Ground Zero and paid their respects to the victims of September 11th. Tony Busey, lead singer of VonAmp said, "You just can't comprehend it until you see the devastation. The whole thing makes me sad that it ever happened."
Taylor Barrett agreed adding, "We'll never forget that day and we'll keep them in our prayers." On VonAmp's web site, you can see a photo of the band members at ground zero: http://www.vonamp.com
VonAmp would like to personally thank: River Eagle Distributing, John Bening of the Bening Motor Company, Monster Energy�, The Southeast Missourian, The Branding Iron, The Rude Dog Pub, Style Stop Lifestyles, The Jackson Elk's Lodge, Dr. Branson of Eye Care for You, Rhodes 101 Stop, Broussards Cajun Cuisine, C.P. McGinty Jewelers, Port Cape (Thanks Doc!), Barry Salottolo of the Youth Arts Forum, Roy's Tire, Busey Truck Equipment, the Stoltz family of Marine, IL, Jerry and Pat Busey of Jackson, the Scarpaci Family, the Barrett Family, and the entire Jackson/Cape community.

subset: commoncrawl


text:
New York, NYUSA
May 19, 2013
Hello. I try to keep up with the latest in anime and video games (as well as maintaining a list of the have yet to experience titles). The classics are also great to experience as well.
I like this group. I am going to try to get into the city in order to attend the meetings.
Meetup members, Log in
By clicking "Sign up" or "Sign up using Facebook", you confirm that you accept our Terms of Service & Privacy Policy


text: Filter Quick Purchase Filter By You Searched for Clear All Gender: Kids Color: green Color: purple Gender Men Women Shoe Size 13 4 3 4.5 Length Over-Calf Mid-Calf Crew Micro Mini-Crew Protection Level For feet that hurt For feet that do not hurt Colors white blue blue, dark brown pink yellow black grey khaki grey, dark red orange fibers Exclusive Thor•lon® Acrylic Stretch Nylon Spandex Nylon Thor•wick® Cool Thor•wick® Elastic Polyester 4 Channel Wicking Polyester All Activities Basketball Fitness Golf Running Tennis Walking Skiing Snowboarding Boy Scouts Hiking Trail Running Military Experia® Multi-Sport Highest Rated Lowest Rated Price: $$ - $ Price: $ - $$ Kids's Socks Unfortunately, the filters you have selected do not return any products. Use your browser's "back" arrow button to choose a different filter or clear all of the filters you have selected by clicking the button below. Quick Purchase homepage


text:
'Very Clear': Leader McCarthy's Benghazi Admission
In a single day, Leader McCarthy admitted twice that the Benghazi Select Committee represents nothing more than Republicans playing politics with taxpayer money.
275: October 7th is the 275th day of the 114th Congress 125: Days the GOP House has been in session, including 25 pro-forma days in which the House gaveled in & out in a matter of minutes & no legislative business was completed… Continue
The GOP Calendar of Chaos Gets More Chaotic
House Republicans' complete dysfunction is throwing America into a Calendar of Chaos.
On Ex-Im, House GOP Extremism Failing American Workers
During the course of his disastrous audition to be the next Speaker of the House, GOP Leader Kevin McCarthy said this about the job-creating Export-Import Bank: "Ex-Im – that has failed now, and it should stay failed. I fought hard [to shut… Continue
Americans Paying the Price for House GOP Chaos
House Republicans have descended into chaos. And the GOP's total dysfunction isn't just a PR problem – it's threatening American workers and American businesses.
Terrible Week for the House GOP
To no one's surprise, Speaker-in-waiting Kevin McCarthy and House Republicans have had an epically terrible week. Here's a week-in-review of their obstruction, distraction and dysfunction: Washington Post – Kevin McCarthy gamely tries to clean up Benghazi Hillary polling mess, fails spectacularly The… Continue
Speaker-in-waiting Kevin McCarthy Attempts to Backtrack on His Admission on Benghazi
Appearing on Fox News' Special Report With Bret Baier last night, Speaker-in-waiting Kevin McCarthy attempted to backtrack on his disturbing admission about the Benghazi Committee, painfully noting it was never his plan to confess imply it was "political": Rep. McCarthy to Bret Baier. I did not intend to… Continue
'Dysfunctional and Ineffective'
"A lot of people look at us as being dysfunctional and ineffective." – House Republican Conference Chair Cathy McMorris Rodgers.
#TBT — The Destructive #GOPshutdown Edition
Two years ago today, House Republicans shut down the federal government, costing $24 billion and over 100,000 jobs! These were some headlines dominating the media then: TIME, [10/1/2013] – Federal Government Begins First Shutdown in 17 Years USA TODAY, [10/1/2013] – Government… Continue
GOP on Clean-Up Duty for Leader McCarthy
Leader McCarthy, here's a surefire way to end this mess for yourself: stop wasting taxpayer money on a brazen political smear campaign. Americans deserve better.


text:
Google and Meetup are partners in a program dedicated to driving economic growth, by providing local businesses with tools and resources to get online, and to succeed online. We're excited to bring this opportunity to you - in our very own Meetup.
At this Meetup - we will host a "hands-on" workshop - and you will walk away with:
Note: Please bring a laptop if you have one. We'll be meeting at a place with WiFi.
Because while 97% of Americans look online for local products and services. Now more than ever is the time to get and be FOUND online! Don't be invisible--come to this Meetup to make sure you have an online presence!
I never fail to learn something new from Naoma! This review and presentation of a fantastic 'free' tool for business owners (of which less than 63% have a web presence) was phenomenal, and at less than $21 annually (after the first free year) you CAN NOT beat that price! What a great meeting, presentation, and fun networking event. Thanks Naoma!
0 · October 29, 2011
I decided to start Reno Motorcycle Riders Group because I wanted to be part of a group of people who enjoyed my passion... I was excited and nervous. Our group has grown by leaps and bounds. I never thought it would be this big.
— Henry, started Reno Motorcycle Riders
Meetup members, Log in
By clicking "Sign up" or "Sign up using Facebook", you confirm that you accept our Terms of Service & Privacy Policy


text:
By Alex Temblador A gay couple, Gordon Lake, an American, and his Spanish husband, Manuel, found a surrogate in Thailand. Using Gordon's sperm and an egg donor, a Thai woman carried the baby for the couple and finally gave birth to their baby daughter, Carmen, in January. She handed the daughter over to the two […]
Gay Dad: Our Surrogate, Our Friend
Light at the End of the Tunnel
The Thin Blue Line
By: John Jericiau Waiting 10 days for most anything is difficult, but waiting for the chance to try a pregnancy test is excruciating. I started marking the calendar at day 2 post embryo transfer as I heard myself thinking things like "It's out of our hands now" and "If it's meant to be…" and "My […]
Time Flies!
99.996789% Paternity!
Removing the Arrow
A Surrogate Mom's Best Friend
The Busy Surrogate Has To Let Go Of Something
After the Births: Visits from Surrogates
By: Kelly Rummelhart My journey as a Surrogate does not end at the birth. I have been lucky to match with four marvelous men who agree that staying connected after their children are born is their desire, too. Like I had posted before, I am not vague in my expectations with communication before, during, and […]


text:
Robson's 2015 over after rehab set-back
Laura Robson has been forced to cancel her remaining scheduled events this year as she continues to recover from a series of injuries.
Laura Robson has been forced to cancel her remaining scheduled events this year as she continues to recover from a series of injuries.
British No.1 Johanna Konta made the most of her reprieve at the Linz Open, beating Annika Beck in straight sets.
The defending champ against a qualifier. What seemed like a routine matchup turned into a stunning upset as Roger Federer fell to Albert Ramos-Vinolas at the Shanghai Masters.
Roger Federer was upset in his opening match at the Shanghai Masters on Tuesday by Spanish qualifier Albert Ramos-Vinolas 7-6 (4), 2-6, 6-3.
Nick Kyrgios is on the brink of being suspended for four weeks after the 20-year-old Australian was fined $1,500 for his antics during a match at the Shanghai Open.
US Open champion Flavia Pennetta lost in the first round of the Tianjin Open on Tuesday, falling to Ukrainian qualifier Lyudmyla Kichenok 6-3, 7-5.
Former world No. 1 Lleyton Hewitt has a wild card into January's Australian Open to mark a record 20th straight appearance in his national tennis Grand Slam, which is also likely to be his last.
Andy Murray is likely to play in the World Tour Finals but admitted he could jeopardise his chances by practising on clay in preparation for his main target, the Davis Cup final.
It's alarming to see how easily Novak Djokovic wins these days, especially when you consider the manner in which he crushed Rafael Nadal in the final of the China Open.
French Open champion Stan Wawrinka defeated Benoit Paire 6-2, 6-4 on Sunday to win the Japan Open for his career-best fourth title of the season.
Novak Djokovic and Rafael Nadal will rekindle an old rivalry as the two battle for the China Open championship (live on ESPN3).
Roger Federer fell short at the US Open, but there's nothing like the fall swing to cure his blues. (Federer in action at the Shanghai Masters, Tuesday, 1:30 a.m. ET.)
Rafael Nadal has had little luck against Fabio Fognini this season, which is bad news for the Spaniard ahead of their semifinal clash at the China Open.
Novak Djokovic extended his winning streak to 27 matches at the China Open with a 6-2, 6-2 win over John Isner on Friday to secure a place in the semifinals.
French Open champion Stan Wawrinka overpowered Austin Krajicek 6-3, 6-4 on Friday to advance to the semifinals of the Japan Open.
Ivo Karlovic broke the record for the most career aces after firing down 26 in his second-round match with Pablo Cuevas at the China Open on Thursday.
Novak Djokovic matched Jimmy Connors for the second-longest unbeaten record at an ATP Tour event by beating Chinese wild card Ze Zhang 6-2, 6-1 to improve to 26-0 at the China Open.
Manchester has beaten out London to be revealed as the greatest sporting city in the UK, according to research from ESPN and the universities of Gloucester and Bath.
Play ESPN's Fantasy Rugby for the chance to win some great prizes.
The latest betting tips from the ESPN team, in association with bet365
Watch the very best NCAA College Football LIVE and on-demand with ESPN Player. Available across Europe, subscribe today.
Save 10% off your first order in the ESPNscrum shop. Replica international and club jerseys, official balls and more.


text:
Three human men, six plastic arms, and a literal buffet of slapstick fast food jokes were the highlight of last night's "Tonight Show."
Jim Carrey and Jeff Daniels, who were on the show to promote and debut the trailer for upcoming comedy "Dumb and Dumber To," joined Jimmy Fallon in a clip from "Jacob's Patience," which is definitely a real Canadian soap opera and not at all a fake show that Jimmy Fallon invented for the express purpose of getting famous actors to play with mannequin parts on television.
…Yeah, just kidding. Actually, that's exactly what it is.
Embedded from www.youtube.com.
In this classic scene, Jimmy plays a customer at a burger joint where Jim and Jeff are, respectively, an employee-in-training and an unhinged fast food supervisor. Pro tip: Don't order french fries unless you like them with a bonus side helping of melted mannequin goo.


text:
1 - 2 of 201 of 01
sort by:
- DUNLOP® SP SPORT MAXX GTSP SPORT MAXX GT Summer / Performance Tires by Dunlop®. This modern tire features Multi-Radius Tread Technology™ which helps deliver superb dry handling while maintaining wet traction. Flatter tread profile helps provide an...$308.00 - $892.00 (ea)
- DUNLOP® SP WINTER SPORT 3DSP WINTER SPORT 3D Winter / Performance Tires by Dunlop®. This automotive tire is optimized to handle every kind of winter condition, thanks to three different sipes positioned on specific parts of the tire. It benefits from Dunlop...$135.00 - $457.00 (ea)


text:
Find a copy in the library
Finding libraries that hold this item...
|Television programs
War stories
Television comedies
War television programs
Television series
Video recordings for the hearing impaired
|Material Type:
|Document Type:
|Visual material
|All Authors / Contributors:
Larry Gelbart; Gene Reynolds; Burt Metcalfe; Alan Alda; Wayne Rogers; McLean Stevenson; Loretta Swit; Larry Linville; Gary Burghoff; Twentieth Century-Fox Film Corporation.; Twentieth Century Fox Home Entertainment, Inc.
|OCLC Number:
|Language Note:
|English or French audio tracks, optional subtitles available in English or Spanish; closed-captioned for the hearing impaired.
|Special features: optional laugh track; interactive menus; scene selection.
|Gene Reynolds, Larry Gelbart, Burt Metcalfe.
|Alan Alda, Wayne Rogers, McLean Stevenson, Loretta Switt, Larry Linville, Gary Burghoff.
|Event notes:
|Originally aired on television between September 17, 1972 and March 25, 1973.
|3 videodiscs (ca. 612 min.) : sd., col. ; 4 3/4 in.
|DVD, NTSC, region 1, full-frame format (1.33:1 aspect ratio); Dolby digital mono.
|Disc 1. M*A*S*H, the pilot ; To market, to market ; Requiem for a lightweight ; Chief surgeon who? ; The moose ; Yankee Doodle doctor ; Bananas, crackers, and nuts ; Cowboy --
Disc 2. Henry, please come home ; I hate a mystery ; Germ warfare ; Dear dad ; Edwina ; Love story ; Tuttle ; The ringbanger --
Disc 3. Sometimes you hear the bullet ; Dear dad ... again ; The longjohn flap ; The Army-Navy game ; Sticky wicket ; Major Fred C. Dobbs ; Cease fire ; Showtime.
|Other Titles:
|M*A*S*H (Television program).
M*A*S*H (Television program)
|Twentieth Century Fox Film Corporation ; produced by Gene Reynolds ; associate producer Burt Metcalfe ; developed for television by Larry Gelbart.
Series portrays both the horror and hilarity of the daily lives of MASH (Mobile Army Surgical Hospital) unit 4077 in Korea in 1950.
User-contributed reviews
Similar Items
Related Subjects:(10)
- Korean War, 1950-1953 -- Medical care -- Drama.
- United States. -- Army -- Medical personnel -- Drama.
- Mobile hospitals -- Korea -- Drama.
- Military hospitals -- Korea -- Drama.
- United States. -- Army.
- Armed Forces -- Medical personnel.
- Medical care.
- Military hospitals.
- Mobile hospitals.
- Korea.


text:
You Can Now Order Starbucks via Mobile, Anywhere in the U.S.
For a while now, Starbucks has been trialling a service that allows you to order from an app and then skip the line when you pick up your purchase. Now, that service is being rolled out across the U.S.. Spiced pumpkin lattes all round! »


text:
Mandi Jones Model
Scott PowersPhotographer Male Clarksville, Tennessee, US
My Website: Cruisin' the StreetsMy MM URL: http://www.modelmayhem.com/cruisinthestreets
Mayhem # 748165
About Me
I manage "Cruisin' the Streets" and Cruisin the Streets Magazine. We are always looking for ladies interested in modeling with custom cars, trucks, and motorcycles or would like to be one of our "Featured Model of the Month".
You can see our website and magazine at: www.cruisinthestreets.com
Check us out on Facebook: www.facebook.com/cruisinthestreets
If you are a model and interested in working together contact us. You can do that through MM or send an email to:
Thanks in advance, Scott Powers
Mandi Jones Model
kristinamc... Model
Danielle Gibson Model
Axle Model
Masyn Turner Model
Crae diamond Model
Loading Content


text:
Tag Archives: Pam Carpenter
What to know about voting in Alachua County's spring 2013 local election
The city elections are fast approaching. In order to vote on March 19, you must be a Gainesville resident and you must be registered to vote by Tuesday, Feb. 19.
Early voting ends tomorrow in Florida
Millions of Floridians have already cast their vote during the 96 hours of early voting. The last day of early voting is Saturday, and locations close at 8 p.m.
Absentee ballots offer convenience, risk
Absentee ballots are due Oct. 31.
Law may limit days for early voting
A law being challenged in the Florida federal court could decrease the amount of days to vote early.
New voter cards mailed out in Alachua County
The Alachua County Supervisor of Elections Office has completed the process of transferring all voters to their new precincts and districts. These changes were required after the State completed drawing the new lines for house, senate, and congressional Districts. Alachua County Supervisor of […]
Governor's to post how county election officials scored in recent survey
Governor Rick Scott is releasing a series of rankings for county election officials. State election officials have based these rankings off of how quickly counties reported election results during the January 31st presidential primary and when those counties set up […]


text:
Procedure growth and average selling prices to be affected into 2010, according to Millennium Research Group
WALTHAM, Mass., March 24 /PRNewswire/ -- According to Millennium Research Group's (MRG's) US Markets for Small-Joint Implants 2009 report, which includes arthroplasty implants (shoulder, elbow, digit, ankle, and wrist) and arthrodesis devices (ankle, digit, and wrist), the double-digit market growth seen in recent years will continue despite the global economic downturn. Although the current recession will reduce growth in procedure volumes and average selling prices (ASPs) through 2010, the US small-joint implant market will grow to almost $900 million by 2013.
Given the level of job loss in the US over the past several months and the subsequent loss in health care coverage, procedure growth across many implant segments will be negatively affected. Nevertheless, although a continued lack of confidence for a quick economic recovery is leading to slight deferment in small-joint procedures, growth will remain positive and will continue to increase gradually in most segments.
ASP growth for small-joint implants will also be limited as a result of the global economic slowdown. As healthcare budgets are cut by private insurers, government insurers, and hospitals, device manufacturers will be forced to adjust prices in order to maintain share.
"Once the economy recovers, numbers will pick back up. We're seeing an almost 14% compound annual growth in market revenues through 2013," says Kevin Flewwelling, Manager of the Orthopedics division at MRG. "With the COBRA act and President Obama's 65% COBRA subsidy, we expect the economic downturn to only have a minimal effect on the long-term outlook of the small-joint implant market."
MRG's US Markets for Small-Joint Implants 2009 report provides coverage of key industry competitors, including Ascension Orthopedics, Bi
|SOURCE Millennium Research Group
Copyright©2009 PR Newswire.
All rights reserved


text:
Mark Reynolds, you know the 24 y/o ripping apart opposing pitchers to the tune of a .280 batting average with 5 homers in 50 ABs and a .620 SLG.
This guy is obviously legit, the D-backs felt comfortable having him skip Triple-A to come straight to the majors last year after just 333 minor league games, where he hit .280 with 68 Homeruns and 238 RBIs. I'm not so sure he'll grab superstar status this year, that'll come next year probably, but for this year he'll creep towards the games elite.
The last 2 months of 2007, he stroked the ball at a .319 clip, and hit 9 of his 17 homers in 166 ABs. He still strikes out an awful lot, over that stretch he K'd and incredible 61 times, almost a third of his 188 plate appearences, compared to his 20 walks.
For this year, he looks like Adam Dunn, with a bit less power, and a .285-.295 average, and without any SB potential, because of his astounding k-rate, and power potential.
My projections for this year.
.290 average, 34 Hrs, .360 OBP, .530 SLG
.305, 38 Hrs, .380 OBP, .550 SLG.


text:
Coming up in the next {{countdown}} {{countdownlbl}}
Coming up next:
Skip to this video now
Now Playing:
Play Video
This transcript has been automatically generated and may not be 100% accurate.
Edward Snowden Claims to Be NSA Leaker
Ex-CIA computer specialist says he acted against "horrifying" surveillance programs.
Reported NSA Leaker Comes Forward
Edward Snowden, NSA Contractor, Says He Revealed Secret Documents on Surveillance Programs
Now Playing: Edward Snowden Claims to Be NSA Leaker
Now Playing: Reported NSA Leaker Comes Forward
Now Playing: White House Reacts to NSA Whistleblower Revelation
Now Playing: Surprise Winner of Nobel Peace Prize
Now Playing: Malala Yousafzai Opens Up About New Film, 'He Named Me Malala'
Now Playing: Doctors Without Borders Demands Investigation After Deadly Hospital Airstrike
Now Playing: Group Calls for Independent Probe Into Deadly Hospital Attack
Now Playing: Report: FBI Helps Bust International Nuclear Smuggling Plot
Now Playing: Afghan Forces Requested US Airstrike That Hit Kunduz Hospital
Now Playing: ISIS Destroys Another Ancient Landmark
Now Playing: Doctors Without Borders Calls US Airstrike a 'War Crime'
Now Playing: Scientists Discover Over 200 New Species
Now Playing: Marriage and Sexuality Front and Center Issues Discussed at the Vatican
Now Playing: Destruction of a Hospital In Afghanistan Leaves 22 Dead
Now Playing: U.S. at Odds With Russia Over Syrian Airstrikes
Now Playing: Rep. Tom Cole: McCarthy Benghazi Comments Not His Most Artful Moment
Now Playing: Anne-Marie Slaughter: Hillary Clinton Right on Syria No Fly Zone
Now Playing: Donald Trump on Russia Strikes in Syria
Now Playing: One-on-One With the Queen of Jordan
Now Playing: Benjamin Netanyahu Stares Down the UNGA
Now Playing: Residents in England Evacuated Due to Massive Sinkhole
Now Playing: Russia Launches 1st Airstrikes in Syria
Now Playing: {{itm.title}}


text:
Feel free at ringtones service Audiko.net, where it's possible to search for hot ringtones for your smartphone. Today we have a ringtone of "Bahama Mama" by Boney M as well as 1111 other ringtones by Boney M. "Bahama Mama" is one of the best tracks from the "The Collection" album that was recorded and mixed by Boney M at their major label together with other 33 tracks. You can listen to all 4 Boney M – "Bahama Mama" ringtone variations available here and download it for free right to your smart phone. You can also get other 23 albums produced by Boney M for all time. "Bahama Mama" is referred to Disco, and we can offer you a huge amount of Disco videos absolutely for free. And finally, we have collected lyrics for this track and you can view it here as well. So feel free to browse, listen, download ringtones at Audiko.net. Make your phone sound cool!
Similar Ringtones
Browse Genres
70s Classic Rock Dance Disco Rock best
Albums by Boney M
Boney M
Top ringtones by Boney M
New ringtones
- Unknown - 100_kila_feat_dj_diamondz_-_аз_съм_6_official_hd_video_
- BANUS - lynyrd-skynyrd-free-bird372484
- Hacienda - Quizás quieres saber
- Breaking Bad - Lydia
- ring - New Ringtone 1
- tragedie - Tragedie - OH
- Nico & Vinz - Am I Wrong
- Sam Feldt - Show Me Love [feat. Kimberly Anne]
- tragedie - OH
- Zanon SHK - Ale Valencia


text:
content violation
You can write your comment.
We detected this website has 4 keywords. This is a good count for search engines as it has keyword meta and it doesn't contain more than 260 characters.
It is better to have a validated background for any website to be accesible from more browsers. This website has 3 error(s) and 0 warning(s). We highly recommend for this website to check out its error list and correct them as soon as possible.
Most people tend to type simple phrases on search engines instead of typing url on the address bar to access any website. Unfortunately we couldn't get search query data for this website yet and continuing our researches.
livingwd.org domain expires on 13.10.2015. If you are interested in this domain, you can contact the owner or wait for 0 days.
Title of this website is Living Word Christian Center. And it has Living Word Christian Center, LWCC, Dr. William S. Winston, Dr. Winston keywords. A short summary for this page is
Living Word Christian Center is a Word of Faith, non-denominational, full gospel church. Our mission is reaching and harvesting lost souls for Christ and teaching the Body of Christ how to effectively.... We found out encoding of this website is utf-8.
We located it in 126.96.36.199,
This domain has been created on 13.10.2015 and its latest update is in 13.10.2015. Domain will be expired on 13.10.2015. Nameservers are and . Found these information on whoIs server . Domain registrar is .
lv985.com is ranked #0in the world. 巴黎世家 085332 条纹 is the most searched query for this domain.
latitudeagency.com is ranked #2447106in the world. google branding is the most searched query for this domain.
livecricketlive.com is ranked #19201715in the world. watch live cricket is the most searched query for this domain.
la-letra.com is ranked #3367124in the world. letras de canciones is the most searched query for this domain.
la98radiolatina.com is ranked #3554007in the world. radio latina is the most searched query for this domain.
labandadiario.com is ranked #1484917in the world. fiesta de la abuela carabajal is the most searched query for this domain.
lacapital.com is ranked #2671893in the world. lacapital.com is the most searched query for this domain.
lacuerveriaweb.com.ar is ranked #0in the world. la cuerveria is the most searched query for this domain.
ladorrego.com.ar is ranked #565337in the world. la dorrego is the most searched query for this domain.
lagaceta.com is ranked #0in the world. la gaceta is the most searched query for this domain.
Country Idea is simply based on websites' distrubutions on countries. We help people to get an idea of which websites are popular in which countries, which nations look for what on internet, general information about the country of any website belongs and many little details. Users can also see which site is more successful in which country by comparing essential data such as Alexa Rank, Google Page Rank, etc.
We provide a variety of surveys for our users and save answers to our database. This gives us a unique new statistic of people preferences distributed on countries. We try to collect data in order to understand people better, such as life styles, eating and drinking habbits, thoughts about other countries and other websites belong to other countries.


text:
Couture Mobile Spa "Prom Party" starting at only $299 for 8 guests
Couture Mobile Spa "Prom Party" starting at only $299 for 8 guests ...Read more ›
Couture Mobile Spa "Prom Party" starting at only $299 for 8 guests ...Read more ›
Atlanta police shot and killed a 25-year-old woman, who may have been handcuffed in the back of a police car, after she allegedly pulled a gun and fired twice on Thursday evening, according to The Huffington Post. Alexia Christian, a Black mother of two, died at a hospital after the alleged gunfight, the report says. The incident occurred about 4:30 p.m. Thursday, when Christian was placed in the rear of a ...Read more ›
ORIGINAL: BALTIMORE WOMAN BEATS RIOTER SON BALTIMORE WOMAN BEATS RIOTER SON / MOM ATTACKS RIOTING SON IN BALTIMORE (VIDEO) Baltimore Woman Beats Rioter Son, Hailed As 'Mom Of the Year' - Mom Attacks Son A woman in Baltimore is being hailed as the "Mother of the year" after a video showed her beating her teenage son for participating in the riots that erupted in Baltimore, USA, after the funeral of Freddie G ...Read more ›
The family of Freddie Gray held a peaceful and moving memorial service for the 25-year-old Baltimoreman at New Shiloh Baptist Church on Monday morning. Few would have expected that after such an affair, just blocks away, would be a scene of unrest that the city hasn't seen since the tail-end of the Civil Rights Movement. As the nation peers from the outside at the ongoing situation in the streets of Charm C ...Read more ›
"A white police officer in North Charleston, S.C., was charged with murder on Tuesday after a video surfaced showing him shooting in the back and killing an apparently unarmed black man while the man ran away The officer, Michael T. Slager, 33, said he had feared for his life because the man had taken his stun gun in a scuffle after a traffic stop on Saturday. A video, however, shows the officer firing eig ...Read more ›
St. Louis County prosecutor Bob McCulloch released the findings of a federal autopsy report onMichael Brown Monday, UPI reports Per the findings, Brown died from close-range gunshot wounds to his head and had marijuana in his system at the time of his killing. The Armed Forces Medical Examiner System performed the autopsy—the third done thus far—at the request of the Justice Department. It ruled Brown's dea ...Read more ›
U.S. Representative, District 20 from MyElection General Compare All Counties Compare by County Candidate Party Votes Received Jay Bonner REP 28,924 18.39% Alcee L. Hastings DEM 128,325 81.61% 157,249 Total U.S. Representative, District 21 from MyElection General Compare All Counties Compare by County Candidate Party Votes Received Ted Deutch DEM 153,118 100% W. Michael Trout WRI 0 0% 153,118 Total U.S. Rep ...Read more ›
On Tuesday, two officers from the St. Louis Metropolitan Police Department shot and killed Kajieme Powell, who was 25 years old. Powell was suspected of shoplifting energy drinks and donuts from a convenience store. The shop owner, believing that Powell was carrying a weapon, contacted police. Another witness, Ald. Dionne Flowers, who represents the area and owns a beauty salon in the same block, noticed th ...Read more ›
By Michael Arceneaux It's Time For Men To Help Fight Street Harassment This Week In Obama Crazy Talk: Lauren Ingraham, Stacey Dash & Sarah Palin Ray Nagin: I Was 'Targeted' By the Feds Where Are The Jobs? The Labor Secretary Explains Just Broke Up? Blame Twitter NewsOne On TV One: Daily 9AM EST Home » NewsOne Original » The KKK Tries To Lure New Members With Sweet Treats The KKK Tries To Lure New ...Read more ›
Ukraine (AP) — A Ukrainian official said a passenger plane carrying 295 people was shot down Thursday over a town in the east of the country, and Malaysian Airlines tweeted that it lost contact with one of its flights over Ukrainian airspace. Anton Gerashenko, an adviser to Ukraine's interior minister, said on his Facebook page the plane was flying at an altitude of 10,000 meters (33,000 feet) when it was ...Read more ›
Site Designed By NoRegretMedia.com


text:
My favorite M42 lens is a Vivitar Series 1 135mm f2.3. I like it for head and shoulder portraits and for close-ups of eyes only>
Printable View
My favorite M42 lens is a Vivitar Series 1 135mm f2.3. I like it for head and shoulder portraits and for close-ups of eyes only>
Don't forget Tamrom Adaptall lenses - I think they have M42 adapters. The Tamron 90mm MACRO produces pretty good results and seems to be another popular choice with the M42 crowd.
My fvorite is the Takumar 17/4 Fisheye
However, the 50/1.4 and the 135/3.5 are the ones i use most.
I also have a 35mm but haven't used it much.
I just picked up a Helios 44-2 58mm f:2 - an M42 to PK adapter is on the way :)
Helios 44-2 58/2 very nice lens. i tried a lot of lenses but this has something, i cant explain what- maybe nice colors and sharpness.
Ricoh 55/1.4
Vivitar Series 1 135/2.3, 200/3, 90/2.5 Macro, 70-210/3.5 (ver 1)
The 50/55 lenses cost me about $15 each and the Vivitars were all under $50. I use them on either a Spotmatic or Ricoh TL or with an M42/K adapter on either a Chinon CP6 or Ricoh XR1. Mt favorit lens is the 135/2.3.
With this particular lens, everything really depends on where and when was it made - you see, Helios-44-2 name was a nightmare for many Soviet photographers, and an excellent example of how the optics shouldn't work... but as always, in the whole inferno of these lenses one can find a diamond :)
Originally Posted by nzeeman
The Takumars, of course, and many many Soviet and DDR-made lenses are still in my posession and use - a fabulous titanic Helios-40 85/1.5, a small Makro-Flectogon 35/3.5, Orestor 100/2.8 and 135/3.5, a strange but amazing Industar-61 L/Z, and others. I also cured my 50/1.4 Takumar from yellowing by intense UV irradiation, so I can shoot slides with it now without any cast :)
Most of the non-"normal lens" Fujinons are exceptional, especially the ones with EBC coatings. The 50/1.4 Takumar is legendary.
The 55/1.8 Super-Takumar is one of the great all-time "sleeper" lenses. It gets overshadowed by its "big brother", the 50/1.4, but I think it is every bit as good or better than the 50/1.4. Has a subtle but unique "signature", particularly close-up. I've been shooting this lens for 35 years. If I had to give up all gear except one lens, it would be a tough call between this lens and one of the 1950's Schneider Xenon's.


text:
The Portland Pirates announced today that the team has signed defensemen Bryce Lampman and Russ Sinkewich to professional tryout contracts and defenseman Boris Valabik to an AHL contract with the Pirates.
Valabik, 26, was a first-round draft choice (10th overall) by the Atlanta Thrashers in 2004. He has appeared in 187 career AHL games with Chicago, Providence and Wilkes-Barre/Scranton, totaling four goals, 27 assists, 640 penalty minutes and a plus-27 rating.
A member of the 2008 Calder Cup champion Chicago Wolves, the native of Nitra, Slovakia, has seven assists and 210 PIM in 80 career NHL games with Atlanta.
Lampman, 30, had been playing with Orlando (ECHL) this season, tallying three goals and nine assists in 21 games. In 386 AHL contests with Hartford, Norfolk, Iowa, Peoria and Houston, the native of Rochester, Minn., has recorded 33 goals and 84 assists for 117 points.
Lampman has also skated in 10 NHL games with the New York Rangers.
Sinkewich, 27, has three goals and two assists in 11 ECHL games with Gwinnett this season. The native of Westlake, Ohio, has skated in 41 career AHL games with Lake Erie, Milwaukee, Abbotsford and Bridgeport, notching two assists and a plus-4 rating.
- Barracuda affiliation gives Sharks advantage
- UND alums cherish return to Ralph
- 2015 preseason schedule and results
- #AHLFanFridays: Jimmy Murphy
- AHL Hall of Fame announces Class of 2016
- Pasquale on the rebound with IceCaps
- MacIntyre honors late uncle with new number
- Green ready for third season with Utica


text:
You know the situation: You're anywhere, need internet access and got lots of open wifi hotspots within reach.
Trying each hotspot by hand? No!!!
Trying each hotspot by hand? No!!!
WiFi Internet Finder automatically connects to one after the other wifi hotspot and tries to get internet access for you.
If a hotspot providing internet access was found, the app immediately stops the checking process and you can start
surfing the internet.
-Only use the internet if you're sure that the hotspots owner agrees!
-Don't use this app for bad / illegal purposes!
ill give you perfect 5 if it is working .i hope you will
Assome Relly works yayyy! you should Add a pro version!
nice gud
Not helpful.. It glitches on me..
What's New
v1.02 small changes
Turn on the portable WiFi hotspot feature with a single touch.


text:
Shopping Guides
Top Brands in Blu Ray Hd Dvd Players
Most Popular Products
Samsung Blu-Ray Players 3D Blu-ray Player with Built-In Wi-Fi BD-J5900ZA
Shop for Electrical at The Home Depot. Enjoy wireless content sharing and streaming with the Samsung BD-J5900 3D Blu-ray Player ...
Home Depot
Yamaha BD-S677 bluray disc player
bluray disc player plays 3D and standard Blu-ray discs, DVDs, CDs, and SACDs,built-in Wi-Fi for streaming VUDU and YouTube(tm) videos,free ...
Funai Combination VCR and DVD Player DV220FX5
Sleek device plays VHS tapes, DVDs, and CDs; input line lets you record live TV to a videotape Gender: Unisex. ...
Samsung Blu-Ray Players Blu-ray Player with Streaming Capability BD-J5100ZA
Shop for Electrical at The Home Depot. The Samsung BD-J5100 is way more than yesterday's Blu-ray player; it's your gateway ...
Home Depot


text:
HCHC Home » About HCHC » News and Events » Hellenic College Students in California
Hellenic College Students in California
A contingent of Hellenic College and Holy Cross students is in Ontario, California, attending the Metropolis of San Francisco Folk Dance Festival. They will remain there through the weekend to meet festival participants and other interested people and speak to them about the educational opportunities at Hellenic College and Holy Cross.
Below is a list of upcoming events at Hellenic College Holy Cross. For a complete list, please refer to our Campus Calendar.
Liturgy on the Streets with Missions
Oct 10 7 am
Columbus Day - No Classes, Offices Closed
Oct 12
HC vs. HC Flag Football
Oct 12
HCHC Alumni Ice Cream Social
Condakes Refectory
Oct 13 6:45 pm
Missions Meeting
Oct 13 9 pm
Career & Internship Fair
Maliotis Cultural Center
Oct 15 12 pm


text:
Careers at Landscape Leadership
We are constantly seeking talented and passionate marketing professionals to join our team. We accept and review resumes for all positions, including interns and freelance contractors.
Benefits include:
- Competitive compensation. We offer a base salary and a formal quarterly bonus.
- Be based or move anywhere. As a team we work 100% remotely. Work in your underwear. We don't care.
- Monthly co-working stipend. Need to be around actual humans? An allowance to get out and about is available after your first three months.
- Loose vacation policy (i.e.- we don't keep track). Take vacation when you need it so you can recharge and come back fresh. Once each year we actually pay for your flight to go on vacation.
- Annual company retreat (Austin 2014, San Antonio 2015, Charleston 2016?) and annual attendance at HubSpot's Inbound conference.
- Stay healthy. All employees receive medical benefits.
- Awesome team and clientele. You'll be collaborating with a fantastic group of smart, driven, principled, good-spirited people. Our clients are the same (if they weren't, we wouldn't be working together!)


text:
"Wink of an Eye" is an award-winning private eye mystery by North Carolina author Lynn Chandler Wills (St. Martin's Minotaur, $24.95 hardcover) set in the small West Texas town of Wink.
Texas A&M University Press has published "Growing Grapes in Texas: From the Commercial Vineyard to the Backyard Vine" by horticulturist Jim Kamas ($25 flexbound).
The Texas Folklore Society and the University of North Texas Press have joined forces to publish two books about small-town life in Texas. Each is $19.95 hardcover.
"Migratory Animals," an introspective first novel by Austin writer Mary Helen Specht (Harper Collins, $14.99), makes its debut Tuesday.
Three gorgeous new cookbooks offer hundreds of Texas recipes for serious cooks, featuring mostly Texas-grown produce.
All three are hefty volumes loaded with mouth-watering recipes and beautiful color photographs.
Coffee table books make nice holiday gifts, and Texas publishers have four new ones to choose from this season.
I've never been to Utopia, Texas (population 227 in 2010), but every couple of years or so it seems a new book comes out set in the town with such an enticing name.
The Great Texas Line has published a new, expanded edition of Anne Dingus' "More Texas Sayings Than You Can Shake a Stick At," with about 200 new quips and about 1,600 in all packed into 80 pages ($5.95 paperback).
Fort Worth author Carmen Goldthwaite has a second book of stories about Texas women just published by The History Press - "Texas Ranch Women: Three Centuries of Mettle and Moxie" ($19.99 paperback, 188 pages).
Best-selling Christian author Max Lucado's newest book is "Before Amen: The Power of a Simple Prayer" (Thomas Nelson, $19.99 hardcover).
Our Websites
Our Products
A-J Services
Lubbock Avalanche-Journal ©2015. All Rights Reserved.


text:
1998 Ford F-150 • 180,000 miles
How many wires go back on the starter
October 9, 2012.
October 9, 2012.
There are only two wires that actually hook to the starter mnotor itself positive and negative. To avoid any confusion ai am sending you wiring diagrams for the starter circuit one is for automatic transmission the other for manual tranmission and that one is labeled manual.
So it should be easy to see the relay and everything.
So it should be easy to see the relay and everything.
Oct 9, 2012.
Oct 9, 2012.
1994 Toyota 4 runner in great shape with a dealer rebuilt v6 about 25k on new motor. I turn the key it clicks at the starter. After finding the starter most well hidden ive ever found ...
2 answers • 1994 Toyota 4Runner • 200 miles


text:
Towards a Generic Feature-Selection Measure for Intrusion Detection.
ABSTRACT Performance of a pattern recognition system depends strongly on the employed feature-selection method. We perform an in-depth analysis of two main measures used in the filter model: the correlation-feature-selection (CFS) measure and the minimal-redundancy-maximal-relevance (mRMR) measure. We show that these measures can be fused and generalized into a generic feature-selection (GeFS) measure. Further on, we propose a new feature-selection method that ensures globally optimal feature sets. The new approach is based on solving a mixed 0-1 linear programming problem (M01LP) by using the branchand-bound algorithm. In this M01LP problem, the number of constraints and variables is linear (O(n)) in the number n of full set features. In order to evaluate the quality of our GeFS measure, we chose the design of an intrusion detection system (IDS) as a possible application. Experimental results obtained over the KDD Cup '99 test data set for IDS show that the GeFS measure removes 93% of irrelevant and redundant features from the original data set, while keeping or yielding an even better classification accuracy.
Full-textDOI: · Available from: Katrin Franke, Sep 27, 2015
- SourceAvailable from: Monowar H. Bhuyan
[Show abstract] [Hide abstract]
- "The authors establish the effectiveness of their method in terms of efficiency in intrusion detection without compromising the detection rate. An example filter model for feature selection is [62], where the authors fuse correlation-based and minimal redundancy-maximal-relevance measures. They evaluate their method on benchmark intrusion datasets for classification accuracy. "
ABSTRACT: Network anomaly detection is an important and dynamic research area. Many network intrusion detection methods and systems (NIDS) have been proposed in the literature. In this paper, we provide a structured and comprehensive overview of various facets of network anomaly detection so that a researcher can become quickly familiar with every aspect of network anomaly detection. We present attacks normally encountered by network intrusion detection systems. We categorize existing network anomaly detection methods and systems based on the underlying computational techniques used. Within this framework, we briefly describe and compare a large number of network anomaly detection methods and systems. In addition, we also discuss tools that can be used by network defenders and datasets that researchers in network anomaly detection can use. We also highlight research directions in network anomaly detection.IEEE Communications Surveys & Tutorials 03/2014; 16(1):303-336. DOI:10.1109/SURV.2013.052213.00046 · 6.81 Impact Factor
Article: Computational intelligence in security for information systems. 4th international conference, CISIS 2011, held at IWANN 2011, Torremolinos-Málaga, Spain, June 8–10, 2011. Proceedings


text:
Victoria University
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
TripAdvisor Reviews Victoria University Toronto
Travel Blogs from Toronto
A Quick Tour of London & That's a Wrap
... a bit of East London near the old City's "square mile", which was quite interesting. It also killed some time as we were meeting our landlady from the place we stay in Bequia every winter for dinner at Brown's ...
Saturday 13th June
... After grabbing a hot dog, we spent some time here in the sun.
CA$2 for a hot dog.
After more sitting around in the park and waterfront we got a drink and a doughnut from Tim Hortons, as this would be our last chance. The cafe/bakery sells doughnuts coffee, drinks as well as sandwiches. I had an Oreo doughnut and a frozen lemonade, both of which were lush!
CA$3.50 for doughnut and lemonade including tax.
We finished off our time in Canada ...
Day 7: Seeking warmth in Toronto
... lug the coat and vest around, so we decided to take them back to the loft. Ray had spotted some interesting graffiti next to the LBCO so suggested he take photos of that while I head to the loft to drop off the clothing. We passed Buddy and exchanged our familiar greeting - always noting the current weather - and armed with the Key-of-Stubbornness I continued past the grafitti, leaving Ray to do his thing. At the loft I managed to get the key to turn in under 3 minutes so felt ...
One more leg notched up
... did the seat jive for a while....and it seemed the 5 hrs blew by.
They are saying a quick stop because we are late....and we are staying on the same plane...said no time to bother getting off....wash the windows top up the gas for the biggggggg pond jump. 15 hrs next leg. Wow I made it a whole hour and half from home as the crow flies so far sighhhhh. Think I'm slurring in my ...
And We're Back...
... It's another to get somewhere where we get second looks (and sometimes stares) because it's so rare for tourists to visit. It was places like these where we ended up with some of the most memorable and authentic experiences and visiting was always worth the effort.
One of the things we've taken from ...
Other places to stay in Toronto
Hostelling International TorontoDowntown, Toronto | Hostelfrom $29
Clarence CastleEntertainment District, Toronto | Hostelfrom $27
All Days House #3Rosedale, Toronto | Hostelfrom $45
Global Village BackpackersEntertainment District, Toronto | Hostelfrom $46
Planet TravelerDowntown, Toronto | Hostelfrom $25
Canadiana BackpackersEntertainment District, Toronto | Hostelfrom $24
Neill-Wycik College HotelDowntown, Toronto | Hostelfrom $60
Kensington Guest HouseDowntown, Toronto | Hostelfrom $35
Marigold International Traveler's HostelWest Toronto, Toronto | Hostelfrom $89
Dundas Square HotelDowntown Toronto, Toronto | Hostelfrom $59
St. Michael's College81 St. Mary Street, Toronto | Hostelfrom $250
525 InnDowntown, Toronto | Hostelfrom $35
Toronto Travellers HomeDowntown, Toronto | Hostelfrom $32
Global Village KensingtonDowntown, Toronto | Hostelfrom $53
Pacificmall Travelers HomeMilliken, Toronto | Hostelfrom $54
All Days House#2Downtown, Toronto | Hostelfrom $62


text:
Chauvet COLORstrip - DMX LED Linear Wash Light
Out of stock
The Chauvet COLORstrip - DMX LED Linear Wash Light is designed for uplighting and eye-candy effects. It can be controlled by 4 DMX channels and has 384 light sources used for several operations such as flash, color chase, color fade patterns and color mixing. It can be automated as well as sound activated and is ideal for applications such as lighting up a catwalk. Buy yours today from UniqueSquared.com


text:
French anti-nuclear activists are hunger-striking their way onto the political agenda.
Issues / War & Peace
Iran's nuclear concessions roll off the P5+1 like water from a duck's back.
Thanks in part to U.S. announcement of deployment of an ABM system in Japan, the smoldering between Japan and China could burst into open flames.
U.S. policies toward the Middle East were more of a factor in protests against "Innocence of Muslims" than insults to religion.
A prominent disarmament and nonproliferation advocate gives his surprise endorsement to an attack on Iran.
Mexican families touched by the drug war have brought their Caravan for Peace to the U.S., laying the groundwork for a binational peace movement.
One of the Washington Post's star reporters has assigned herself the task of scaring up funds for "nuclear modernization."
War with Iran could spark a regional conflagration that would cause untold suffering across the Muslim world and spark deadly blowback for decades to come.
On Israeli Prime Minister Netanyahu's personal tachometer of war, the needle is always at the red line.
The man who translated and promoted "Innocence of Muslims" is a one-man anti-Islam P.R. firm.


text:
Prospect Historic Hotel - Motel and Dinner House
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
How has this hotel rated in the past?
Travelers also recommend:
TripAdvisor Reviews Prospect Historic Hotel - Motel and Dinner House
Travel Blogs from Prospect
Crystal Clear Crater Lake
... is perfect harmony.
After the eruption, this place became a prominent ritual site for local tribes such as the Klamath. Spirits and particular powers inhabit the terrain. Even today private ceremonial activities and Vison Quests take place here. I once looked into embarking on a Vision Quest myself. This would be a perfect location.
There is a 33 mile road encircling the lake called "The Rim Drive". It offers many pullouts, ...
Rogue River Waterfalls and Lava Tube
... park, we stopped to take some photos of the river. A running river through forest has got to be one of the most beautiful scenes.
The, one day while up near Crater Lake, we took off hiking through the forest to see the Mill Creek Waterfall and the Barr Creek ...
Crater Lake!
... br>
We started out toward Crater Lake National Park on one of my favorite scenic highways, OR 138 along the North Umpqua River. A very helpful woman in the Visitor Center in Roseburg gave us a map to all the waterfalls along the way. We took several short hikes to see the ones closest to the highway. Too bad I can't remember all their names--maybe someone can help me out!
Another ...
Blue Blue Crater Lake
... landscape. It is estimated that about 720 years was required to fill the lake to its present depth of 594 m (1,949 ft). Much of this occurred during a period when the prevailing climate was less moist than at present.
http://en.wikipedia.org/wiki/Crater_Lak e
Not only is the lake gorgeous to view, but ...
Chapter 41 Coast, Mountains & Waterfalls
... it was as we came
around a sweeping bend, the blue Pacific lapping the golden sand on the west
I was
thinking to myself, these same waters are now washing ashore on the east coast
of Australia. Such a huge expanse of
Seattle we were heading south and had chosen the route that follows Highway
101, known in this neck of the woods at the "Pacific Coast Scenic Byway" and
scenic byway ...


text:
Image Unavailable
- Sorry, this item is not available in
- Image not available
- To view this video download Flash Player
|List Price:
|$88.00 + $19.95 shipping
|You Save:
|$2.00 (2%)
Makes meditation easier and more comfortable, especially for those who have trouble crossing their legs. Features a 7" wide seating area. The curved bottom edge on the bench legs allow you to rock slightly for perfect alignment. Folding legs allow you to easily take it with you.
Product Details
Would you like to give feedback on images?
Well made and comfy. I've recommended this item to several people.Published 7 months ago by Lisa A Mielke
Great bench. It takes alot of weight and pressure off of your legs. The construction is very sturdy and seems to be very durable. Read morePublished 10 months ago by Amazon Customer
This has become my go to quiet spot, wherever I place it. Easy to stash in my car once it is folded up and super comfortable. Might add a small pillow on top. Read morePublished 13 months ago by snoWYmonkey


text:
July 2, 2014
I have been vegetarian for 7 years. I am now mostly vegan and have been for the past year.
The Zenith by a mile. After that a large number of restaurants fight for the #2 spot.
I consider myself to be a good cook and love to cook. I always look foward to pot-lucks.
I would at least like to meet more vegans/vegetarian in the area. I would love to host pot-lucks and similar events! If I can find the time in my crazy work scheduel I would love to help contribute to the cause anyway I can.
I moved to Pittsburgh in late 2013 after living in central PA for the past two-ish years. I see that the area has a very active vegan community which makes me super excited!
Meetup members, Log in
By clicking "Sign up" or "Sign up using Facebook", you confirm that you accept our Terms of Service & Privacy Policy


text:
Are you Ying Xu?Claim your profile
Publications (310)1454.43 Total impact
Article: Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses[Show abstract] [Hide abstract]
ABSTRACT: Sheep red blood cells (SRBCs) have long been used as a model antigen for eliciting systemic immune responses, yet the basis for their adjuvant activity has been unknown. Here, we show that SRBCs failed to engage the inhibitory mouse SIRPα receptor on splenic CD4(+) dendritic cells (DCs), and this failure led to DC activation. Removal of the SIRPα ligand, CD47, from self-RBCs was sufficient to convert them into an adjuvant for adaptive immune responses. DC capture of Cd47(-/-) RBCs and DC activation occurred within minutes in a Src-family-kinase- and CD18-integrin-dependent manner. These findings provide an explanation for the adjuvant mechanism of SRBCs and reveal that splenic DCs survey blood cells for missing self-CD47, a process that might contribute to detecting and mounting immune responses against pathogen-infected RBCs.Immunity 10/2015; DOI:10.1016/j.immuni.2015.08.021 · 21.56 Impact Factor
Article: The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function[Show abstract] [Hide abstract]
ABSTRACT: Regulatory T cell (T reg cell) numbers and activities are tightly calibrated to maintain immune homeostasis, but the mechanisms involved are incompletely defined. Here, we report that the lysophosphatidylserine (LysoPS) receptor GPR174 is abundantly expressed in developing and mature T reg cells. In mice that lacked this X-linked gene, T reg cell generation in the thymus was intrinsically favored, and a higher fraction of peripheral T reg cells expressed CD103. LysoPS could act in vitro via GPR174 to suppress T cell proliferation and T reg cell generation. In vivo, LysoPS was detected in lymphoid organ and spinal cord tissues and was abundant in the colon. Gpr174(-/Y) mice were less susceptible to experimental autoimmune encephalomyelitis than wild-type mice, and GPR174 deficiency in T reg cells contributed to this phenotype. This study provides evidence that a bioactive lipid, LysoPS, negatively influences T reg cell accumulation and activity through GPR174. As such, GPR174 antagonists might have therapeutic potential for promoting immune regulation in the context of autoimmune disease. © 2015 Barnes et al.Journal of Experimental Medicine 06/2015; 212(7). DOI:10.1084/jem.20141827 · 12.52 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Tomasetti and Vogelstein recently published two articles in Science proposing that random mutations arising during DNA replication in normal, noncancerous stem cells are key contributors to cancer, based on their observation that there is a strong and positive correlation between the total number of stem cell divisions and the lifetime cancer risk in a tissue. Our recent analyses of their and additional data revealed that there is a fundamental disconnection between their observation and their conclusion. In addition, our data suggest that (1) a combination of basal metabolic rate and oxidative stress level in a tissue offers a more plausible explanation of the lifetime risk of cancers than their model; and (2) somatic mutations may be predominantly selected to serve as facilitators rather than primary drivers of cancer formation. This article is protected by copyright. All rights reserved. © 2015 UICC.International Journal of Cancer 06/2015; 137(11):n/a-n/a. DOI:10.1002/ijc.29639 · 5.09 Impact Factor
Article: Elucidation of drivers of high-level production of lactates throughout a cancer development[Show abstract] [Hide abstract]
ABSTRACT: Lactates play key roles in facilitating or protecting the development of a cancer in most cancer types. While its beneficial effects to cancer development have been extensively studied, very little is known about what derives the high-level production of lactates in a cancer throughout its entire development. Here we present a novel computational analysis of transcriptomic data of nine primary cancer types, plus a few precancerous and metastatic cancer, to address this issue. Our approach is to identify stress types, which are known to play key roles in cancer development and show strong co-expressions with lactate dehydrogenase-A (LDHA), at different stages of cancer development. A number of interesting observations are made through our analyses, including (i) all nine primary cancer types show similar association patterns between stresses and LDHA, namely the strengths of the associations increase from early- to intermediate-stage cancer tissues but then make a substantial down turn at the most advanced stage; (ii) while the detailed stress types associated with LDHA may vary across different cancer types, stresses induced by apoptosis and adaptive immune responses are present universally, suggesting that these two stresses are possibly two key drivers to keep the high-level production of lactates; and (iii) there is a clear distinction between stress types associated with LDHA in precancerous tissues vs. cancer and metastasis tissues. We anticipate that the analyses can provide highly useful information for designing personalized treatments for different cancers at different stages, as stopping lactate production could have devastating effects on a cancer development. © The Author (2015). Published by Oxford University Press on behalf of Journal of Molecular Cell Biology, IBCB, SIBS, CAS. All rights reserved.Journal of Molecular Cell Biology 05/2015; DOI:10.1093/jmcb/mjv031 · 6.77 Impact Factor
Article: Analysis of strand-specific RNA-seq data using machine learning reveals the structures of transcription units in Clostridium thermocellum[Show abstract] [Hide abstract]
ABSTRACT: Identification of transcription units (TUs) encoded in a bacterial genome is essential to elucidation of transcriptional regulation of the organism. To gain a detailed understanding of the dynamically composed TU structures, we have used four strand-specific RNA-seq (ssRNA-seq) datasets collected under two experimental conditions to derive the genomic TU organization of Clostridium thermocellum using a machine-learning approach. Our method accurately predicted the genomic boundaries of individual TUs based on two sets of parameters measuring the RNA-seq expression patterns across the genome: expression-level continuity and variance. A total of 2590 distinct TUs are predicted based on the four RNA-seq datasets. Among the predicted TUs, 44% have multiple genes. We assessed our prediction method on an independent set of RNA-seq data with longer reads. The evaluation confirmed the high quality of the predicted TUs. Functional enrichment analyses on a selected subset of the predicted TUs revealed interesting biology. To demonstrate the generality of the prediction method, we have also applied the method to RNA-seq data collected on Escherichia coli and achieved high prediction accuracies. The TU prediction program named SeqTU is publicly available at https://code.google.com/p/seqtu/. We expect that the predicted TUs can serve as the baseline information for studying transcriptional and post-transcriptional regulation in C. thermocellum and other bacteria. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.Nucleic Acids Research 02/2015; DOI:10.1093/nar/gkv177 · 9.11 Impact Factor
Article: Extraction optimization of total triterpenoids from Jatropha curcas leaves using response surface methodology and evaluations of their antimicrobial and antioxidant capacities[Show abstract] [Hide abstract]
ABSTRACT: Triterpenoids are multifunctional secondary metabolites in plants. But little information is available concerning the actual yield, optimal extraction method and pharmacologic activity with regard to triterpenoids from Jatropha curcas leaves (TJL). Hence, response surface methodology (RSM) was used to optimize the extraction parameters. The effects of three independent variables, namely liquid-to-solid ratio, ethanol concentration and extraction time on TJL yield were investigated. TJL obtained by silica column chromatography was tested against bacterial and fungal species relevant to oral disease and wounds through broth microdilution. Antioxidant activity was assessed using the 2,2-diphenyl-2-picrylhydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) assays.Electronic Journal of Biotechnology 01/2015; 16(2). DOI:10.1016/j.ejbt.2014.12.005 · 0.68 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Gastric cancer is one of the most prevalent and aggressive cancers worldwide, and its molecular mechanism remains largely elusive. Here we report the genomic landscape in primary gastric adenocarcinoma of human, based on the complete genome sequences of five pairs of cancer and matching normal samples. In total, 103,464 somatic point mutations, including 407 non-synonymous ones, were identified and the most recurrent mutations were harbored by Mucins (MUC3A and MUC12) and transcription factors (ZNF717, ZNF595 and TP53). 679 genomic rearrangements were detected, which affect 355 protein-coding genes; and 76 genes show copy number changes. Through mapping the boundaries of the rearranged regions to the folded three-dimensional structure of human chromosomes, we determined that 79.6% of the chromosomal rearrangements happen among DNA fragments in close spatial proximity, especially when two endpoints stay in a similar replication phase. We demonstrated evidences that microhomology-mediated break induced replication was utilized as a mechanism in inducing ~40.9% of the identified genomic changes in gastric tumor. Our data analyses revealed potential integrations of Helicobacter pylori DNA into the gastric cancer genomes. Overall a large set of novel genomic variations were detected in these gastric cancer genomes, which may be essential to the study of the genetic basis and molecular mechanism of the gastric tumorigenesis. This article is protected by copyright. All rights reserved.International Journal of Cancer 12/2014; 137(1). DOI:10.1002/ijc.29352 · 5.09 Impact Factor
Article: A novel chloroplastic isopentenyl diphosphate isomerase gene from Jatropha curcas: Cloning, characterization and subcellular localization[Show abstract] [Hide abstract]
ABSTRACT: Background Jatropha curcas is a rich reservoir of pharmaceutically active terpenoids. More than 25 terpenoids have been isolated from this plant, and their activities are anti-bacterial, anti-fungal, anti-cancer, insecticidal, rodenticidal, cytotoxic and molluscicidal. But not much is known about the pathway involved in the biosynthesis of terpenoids. The present investigation describes the cloning, characterization and subcellular localization of isopentenyl diphosphate isomerase (IPI) gene from J. curcas. IPI is one of the rate limiting enzymes in the biosynthesis of terpenoids, catalyzing the crucial interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Results A full-length JcIPI cDNA consisting of 1355 bp was cloned. It encoded a protein of 305 amino acids. Analysis of deduced amino acid sequence predicted the presence of conserved active sites, metal binding sites and the NUDIX motif, which were consistent with other IPIs. Phylogenetic analysis indicated a significant evolutionary relatedness with Ricinus communis. Southern blot analysis showed the presence of an IPI multigene family in J. curcas. Comparative expression analysis of tissue specific JcIPI demonstrated the highest transcript level in flowers. Abiotic factors could induce the expression of JcIPI. Subcellular distribution showed that JcIPI was localized in chloroplasts. Conclusion This is the first report of cloning and characterization of IPI from J. curcas. Our study will be of significant interest to understanding the regulatory role of IPI in the biosynthesis of terpenoids, although its function still needs further confirmation.Electronic Journal of Biotechnology 11/2014; 17(6). DOI:10.1016/j.ejbt.2014.09.003 · 0.68 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: A computational analysis of genome-scale transcriptomic data collected on ∼1,700 tissue samples of three cancer types: breast carcinoma, colon adenocarcinoma and lung adenocarcinoma, revealed that each tissue consists of (at least) two major subpopulations of cancer cells with different capabilities to handle fluctuating O2 levels. The two populations have distinct genomic and transcriptomic characteristics, one accelerating its proliferation under hypoxic conditions and the other proliferating faster with higher O2 levels, referred to as the hypoxia and the reoxygenation subpopulations, respectively. The proportions of the two subpopulations within a cancer tissue change as the average O2 level changes. They both contribute to cancer development but in a complementary manner. The hypoxia subpopulation tends to have higher proliferation rates than the reoxygenation one as well as higher apoptosis rates; and it is largely responsible for the acidic environment that enables tissue invasion and provides protection against attacks from T-cells. In comparison, the reoxygenation subpopulation generates new extracellular matrices in support of further growth of the tumor and strengthens cell-cell adhesion to provide scaffolds to keep all the cells connected. This subpopulation also serves as the major source of growth factors for tissue growth. These data and observations strongly suggest that these two major subpopulations within each tumor work together in a conjugative relationship to allow the tumor to overcome stresses associated with the constantly changing O2 level due to repeated growth and angiogenesis. The analysis results not only reveal new insights about the population dynamics within a tumor but also have implications to our understanding of possible causes of different cancer phenotypes such as diffused versus more tightly connected tumor tissues.10/2014; 2(3). DOI:10.1007/s40484-014-0032-8
Article: Abstract 4340: The amino acid transporter SLC6A14 is an effective drug target for treatment of pancreatic cancer[Show abstract] [Hide abstract]
ABSTRACT: Pancreatic cancer is the deadliest of all cancers with worst outcome and poor survival rate. Chemotherapy with gemcitabine works well for early stage cancer, but becomes ineffective for advanced-stage cancer. As such, there is a dire need for new approaches to treat this cancer. The metabolism of tumor cells is very different from that of normal cells. In particular, the differences in amino acid metabolism are gaining increasing attention in cancer biology. Selective amino acid transporters are upregulated in cancer in response to the increased demands for amino acids in tumor cells. Such tumor-selective amino acid transporters are logical druggable targets for cancer therapy. As such, pharmacologic blockade of such upregulated transporters would lead to cell death selectively in tumor cells by depriving the tumor cells of essential nutrients. With this in mind, we analyzed 8 different publically available microarray datasets in Gene Expression Omnibus for the amino acid transporters that are upregulatedCancer Research 10/2014; 74(19 Supplement-19 Supplement):4340. DOI:10.1158/1538-7445.AM2014-4340 · 9.33 Impact Factor
- Cancer Research 10/2014; 74(19 Supplement):5174-5174. DOI:10.1158/1538-7445.AM2014-5174 · 9.33 Impact Factor
Article: Identification of Essential Proteins Based on Ranking Edge-Weights in Protein-Protein Interaction Networks[Show abstract] [Hide abstract]
ABSTRACT: Essential proteins are those that are indispensable to cellular survival and development. Existing methods for essential protein identification generally rely on knock-out experiments and/or the relative density of their interactions (edges) with other proteins in a Protein-Protein Interaction (PPI) network. Here, we present a computational method, called EW, to first rank protein-protein interactions in terms of their Edge Weights, and then identify sub-PPI-networks consisting of only the highly-ranked edges and predict their proteins as essential proteins. We have applied this method to publicly-available PPI data on Saccharomyces cerevisiae (Yeast) and Escherichia coli (E. coli) for essential protein identification, and demonstrated that EW achieves better performance than the state-of-the-art methods in terms of the precision-recall and Jackknife measures. The highly-ranked protein-protein interactions by our prediction tend to be biologically significant in both the Yeast and E. coli PPI networks. Further analyses on systematically perturbed Yeast and E. coli PPI networks through randomly deleting edges demonstrate that the proposed method is robust and the top-ranked edges tend to be more associated with known essential proteins than the lowly-ranked edges.PLoS ONE 09/2014; 9(9):e108716. DOI:10.1371/journal.pone.0108716 · 3.23 Impact Factor
Article: Understanding the commonalities and differences in genomic organizations across closely related bacteria from an energy perspective[Show abstract] [Hide abstract]
ABSTRACT: The availability of a large number of sequenced bacterial genomes facilitates in-depth studies about why genes (operons) in a bacterial genome are globally organized the way they are. We have previously discovered that (the relative) transcription- activation frequencies among different biological pathways encoded in a genome have a dominating role in the global arrangement of operons. One complicating factor in such a study is that some operons may be involved in multiple pathways with different activation frequencies. A quantitative model has been developed that captures this information, which tends to be minimized by the current global arrangement of operons in a bacterial (and archaeal) genome compared to possible alternative arrangements. A study is carried out here using this model on a collection of 52 closely related E. coli genomes, which revealed interesting new insights about how bacterial genomes evolve to optimally adapt to their environments through adjusting the (relative) genomic locations of the encoding operons of biological pathways once their utilization and hence transcription activation frequencies change, to maintain the above energy-efficiency property. More specifically we observed that it is the frequencies of the transcription activation of pathways relative to those of the other encoded pathways in an organism as well as the variation in the activation frequencies of a specific pathway across the related genomes that play a key role in the observed commonalities and differences in the genomic organizations of genes (and operons) encoding specific pathways across different genomes.Science China. Life sciences 09/2014; 57(11). DOI:10.1007/s11427-014-4734-y · 1.69 Impact Factor
- Nature 09/2014; · 41.46 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Germinal center (GC) B cell-like diffuse large B cell lymphoma (GCB-DLBCL) is a common malignancy yet the signaling pathways deregulated and the factors leading to its systemic dissemination are poorly defined1,2. Work in mice showed that sphingosine-1-phosphate receptor-2 (S1PR2), a Gα12 and Gα13 coupled receptor, promotes growth regulation and local confinement of GC B cells3,4. Recent GCB-DLBCL deep sequencing studies have revealed mutations in a large number of genes in this cancer, including in GNA13 (encoding Gα13) and S1PR25-7. Here we show using in vitro and in vivo assays that GCB-DLBCL associated mutations occurring in S1PR2 frequently disrupt the receptor's Akt and migration inhibitory functions. Gα13-deficient mouse GC B cells and human GCB-DLBCL cells were unable to suppress pAkt and migration in response to S1P, and Gα13-deficient mice developed GC B cell-derived lymphoma. GC B cells, unlike most lymphocytes, are tightly confined in lymphoid organs and do not recirculate. Remarkably, deficiency in Gα13, but not S1PR2, led to GC B cell dissemination into lymph and blood. GCB-DLBCL cell lines frequently carried mutations in the Gα13 effector ARHGEF1, and Arhgef1-deficiency also led to GC B cell dissemination. The incomplete phenocopy of Gα13- and S1PR2-deficiency led us to discover that P2RY8, an orphan receptor that is mutated in GCB-DLBCL and another GC B cell-derived malignancy, Burkitt lymphoma (BL), also represses GC B cell growth and promotes confinement via Gα13. These findings identify a Gα13-dependent pathway that exerts dual actions in suppressing growth and blocking dissemination of GC B cells that is frequently disrupted in GC B cell-derived lymphoma.Nature 08/2014; 516(7530):254-258. DOI:10.1038/nature13765 · 41.46 Impact Factor
Article: AST: An Automated Sequence-Sampling Method for Improving the Taxonomic Diversity of Gene Phylogenetic Trees[Show abstract] [Hide abstract]
ABSTRACT: A challenge in phylogenetic inference of gene trees is how to properly sample a large pool of homologous sequences to derive a good representative subset of sequences. Such a need arises in various applications, e.g. when (1) accuracy-oriented phylogenetic reconstruction methods may not be able to deal with a large pool of sequences due to their high demand in computing resources; (2) applications analyzing a collection of gene trees may prefer to use trees with fewer operational taxonomic units (OTUs), for instance for the detection of horizontal gene transfer events by identifying phylogenetic conflicts; and (3) the pool of available sequences is biased towards extensively studied species. In the past, the creation of subsamples often relied on manual selection. Here we present an Automated sequence-Sampling method for improving the Taxonomic diversity of gene phylogenetic trees, AST, to obtain representative sequences that maximize the taxonomic diversity of the sampled sequences. To demonstrate the effectiveness of AST, we have tested it to solve four problems, namely, inference of the evolutionary histories of the small ribosomal subunit protein S5 of E. coli, 16 S ribosomal RNAs and glycosyl-transferase gene family 8, and a study of ancient horizontal gene transfers from bacteria to plants. Our results show that the resolution of our computational results is almost as good as that of manual inference by domain experts, hence making the tool generally useful to phylogenetic studies by non-phylogeny specialists. The program is available at http://csbl.bmb.uga.edu/~zhouchan/AST.php.PLoS ONE 06/2014; 9(6):e98844. DOI:10.1371/journal.pone.0098844 · 3.23 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: The Clostridium genus of bacteria contains the most widely studied biofuel-producing organisms such as Clostridium thermocellum and also some human pathogens, plus a few less characterized strains. Here, we present a comparative genomic analysis of 40 fully sequenced clostridial genomes, paying a particular attention to the biomass degradation ones. Our analysis indicates that some of the Clostridium botulinum strains may have been incorrectly classified in the current taxonomy and hence should be renamed according to the 16S ribosomal RNA (rRNA) phylogeny. A core-genome analysis suggests that only 169 orthologous gene groups are shared by all the strains, and the strain-specific gene pool consists of 22,668 genes, which is consistent with the fact that these bacteria live in very diverse environments and have evolved a very large number of strain-specific genes to adapt to different environments. Across the 40 genomes, 1.4–5.8 % of genes fall into the carbohydrate active enzyme (CAZyme) families, and 20 out of the 40 genomes may encode cellulosomes with each genome having 1 to 76 genes bearing the cellulosome-related modules such as dockerins and cohesins. A phylogenetic footprinting analysis identified cis-regulatory motifs that are enriched in the promoters of the CAZyme genes, giving rise to 32 statistically significant motif candidates.BioEnergy Research 06/2014; 7(4). DOI:10.1007/s12155-014-9486-9 · 3.54 Impact Factor
Article: Cancer may be a pathway to cell survival under persistent hypoxia and elevated ROS: A model for solid-cancer initiation and early development[Show abstract] [Hide abstract]
ABSTRACT: A number of proposals have been made in the past century regarding what may drive sporadic cancers to initiate and develop. Yet, the problem remains largely unsolved as none of the proposals have been widely accepted as cancer-initiation drivers. We propose here a driver model for the initiation and early development of solid cancers associated with inflammation-induced chronic hypoxia and ROS accumulation. The model consists of five key elements: (i) human cells tend to have a substantial gap between ATP demand and supply during chronic hypoxia, which would inevitably lead to increased uptake of glucose and accumulation of its metabolites; (ii) the accumulation of these metabolites will cast mounting pressure on the cells and ultimately result in the production and export of hyaluronic acid; (iii) the exported hyaluronic acid will be degraded into fragments of various sizes, serving as tissue-repair signals, including signals for cell proliferation, cell survival and angiogenesis, which lead to the initial proliferation of the underlying cells; (iv) cell division provides an exit for the accumulated glucose metabolites by using them towards macromolecular synthesis for the new cell, and hence alleviate the pressure from the metabolite accumulation; and (v) this process continues as long as the hypoxic condition persists. In tandem, genetic mutations may be selected to make cell divisions and hence survival more sustainable and efficient, also increasingly more uncontrollable. This model also applies to some hereditary cancers as their key mutations, such as BRCA for breast cancer, generally lead to increased ROS and ultimately to repression of mitochondrial activities and up-regulation of glycolysis, as well as hypoxia; hence the energy gap, glucose-metabolite accumulation, hyaluronic acid production and continuous cell division for survival. © 2014 Wiley Periodicals, Inc.International Journal of Cancer 05/2014; 136(9). DOI:10.1002/ijc.28975 · 5.09 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: DMINDA (DNA motif identification and analyses) is an integrated web server for DNA motif identification and analyses, which is accessible at http://csbl.bmb.uga.edu/DMINDA/. This web site is freely available to all users and there is no login requirement. This server provides a suite of cis-regulatory motif analysis functions on DNA sequences, which are important to elucidation of the mechanisms of transcriptional regulation: (i) de novo motif finding for a given set of promoter sequences along with statistical scores for the predicted motifs derived based on information extracted from a control set, (ii) scanning motif instances of a query motif in provided genomic sequences, (iii) motif comparison and clustering of identified motifs, and (iv) co-occurrence analyses of query motifs in given promoter sequences. The server is powered by a backend computer cluster with over 150 computing nodes, and is particularly useful for motif prediction and analyses in prokaryotic genomes. We believe that DMINDA, as a new and comprehensive web server for cis-regulatory motif finding and analyses, will benefit the genomic research community in general and prokaryotic genome researchers in particular.Nucleic Acids Research 04/2014; 42(W1). DOI:10.1093/nar/gku315 · 9.11 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: The GPCR genes have a variety of exon-intron structures even though their proteins are all structurally homologous. We have examined all human GPCR genes with at least two functional protein isoforms, totaling 199, aiming to gain an understanding of what may have contributed to the large diversity of the exon-intron structures of the GPCR genes. The 199 genes have a total of 808 known protein splicing isoforms with experimentally verified functions. Our analysis reveals that 1301 (80.6%) adjacent exon-exon pairs out of the total of 1,613 in the 199 genes have either exactly one exon skipped or the intron in-between retained in at least one of the 808 protein splicing isoforms. This observation has a statistical significance p-value of 2.051762 * e(-09), assuming that the observed splicing isoforms are independent of the exon-intron structures. Our interpretation of this observation is that the exon boundaries of the GPCR genes are not randomly determined; instead they may be selected to facilitate specific alternative splicing for functional purposes.Journal of Bioinformatics and Computational Biology 02/2014; 12(1):1350019. DOI:10.1142/S0219720013500194 · 0.78 Impact Factor
Top Journals
Sichuan University
Hua-yang, Sichuan, China
- • Sichuan Key Laboratory of Resource Biology and Biopharmaceutical Engineering
- • Key Laboratory of Bio-resource and Eco-environment (MOE)
Nankai University
T'ien-ching-shih, Tianjin Shi, China
- College of Information Technical Science
Jilin University
Yung-chi, Jilin Sheng, China
- • College of Computer Science & Technology
- • State Key Laboratory of Inorganic Synthesis and Preparative
University of Missouri
Columbia, Missouri, United States
- Department of Computer Science and IT
University of Georgia
Атина, Georgia, United States
- • Institute of Bioinformatics
- • Department of Biochemistry and Molecular Biology
- • Department of Computer Science
- • Department of Psychology
University of California, San Francisco
San Francisco, California, United States
- Department of Microbiology and Immunology
Sandia National LaboratoriesAlbuquerque, New Mexico, United States
Oak Ridge National Laboratory
Oak Ridge, Florida, United States
- • Biosciences Division
- • Computer Science and Mathematics Division
- • Life Sciences Division
The University of Tennessee Medical Center at KnoxvilleKnoxville, Tennessee, United States
Howard Hughes Medical InstituteAshburn, Virginia, United States
University of California, Riverside
Riverside, CA, United States
- Department of Computer Science and Engineering
Nanjing University of Aeronautics & Astronautics
Nan-ching, Jiangsu Sheng, China
- Department of Biomedical Engineering
Shandong University
Chi-nan-shih, Shandong Sheng, China
- • Department of Pure Mathematics
- • Department of Applied Mathematics
The American Society for Biochemistry and Molecular BiologyАтина, Georgia, United States
Tokyo Denki University
Edo, Tōkyō, Japan
- Division of Mathematical Sciences
University of Alberta
Edmonton, Alberta, Canada
- Department of Computing Science
University of Colorado at Boulder
Boulder, Colorado, United States
- Department of Computer Science (CS)


text:
Exe Lisboa Parque Hotel, Lisbon
- Free WiFi
- Airport within 5 mi/8 km: Lisbon (LIS-Portela)
Main amenities
- 83 guestrooms
- Breakfast available
- Bar/lounge
- Health club
- Self parking
- 2 meeting rooms
- 24-hour front desk
- Air conditioning
- Daily housekeeping
- Library
- Computer station
- Front desk safe
What's around
- In City Center
- Castle of Sao Jorge (1.7 mi / 2.7 km)
- Gulbenkian Museum (0.9 mi / 1.4 km)
- Rossio Square (1.2 mi / 1.9 km)
- Santa Justa Elevator (1.3 mi / 2.1 km)
- Lisbon Cathedral (1.7 mi / 2.7 km)
This is a nice modern hotel in a quiet location that is close to many wonderful Lisbon…
Would stay here again. In walking distance to city centre. A bit hard to locate. Very…
Enter dates to check prices
Hotel Info: 866-266-9798from $132 CAD
- Standard Double or Twin Room
- Triple Child
- Standard Double or Twin Room
- Double or Twin Room, Terrace
- Triple Adult
- Double Room Single Use, Terrace
- Superior Double or Twin Room
- Double Room Single Use
- Double Room Single Use
- Triple Room
Also popular with travellers from Canada
At a glance
Key facts
Hotel size
- This hotel has 83 rooms
- This hotel is arranged over 3 floors
- Check-in time 2 PM-6 PM
- Check-out time is noon
Required at check in
- Credit card deposit required
- Government-issued photo ID required
Travelling with others
- No cribs (infant beds)
- Pets not allowed
Extra people
- Roll-away beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- No parking
- Self parking *
Nearby Four Star Lisbon hotels
In the hotel
- Buffet breakfast (surcharge)
- Bar/lounge
- Coffee shop/café
- 24-hour room service
- Health club
- Number of meeting rooms - 2
- Meeting rooms
- Conference space size (feet) - 1076
- Conference space size (meters) - 100
- Computer station
- 24-hour front desk
- Number of buildings/towers - 1
- Year Built 2003
- Elevator/lift
- Safe-deposit box at front desk
- Library
- Television in lobby
In the room
- Air conditioning
- Minibar
- Private bathroom
- Shower/tub combination
- Free toiletries
- Hair dryer
- Premium TV channels
- Desk
- Free newspaper
- Free WiFi
- Daily housekeeping
Top Lisbon hotels
Recently reviewed hotels in Lisbon
Nearby hotels
Exe Lisboa Parque Hotel, Lisbon's small print
Mandatory fees
Effective January 1, 2016, a tourism tax of EUR 1 per person, per night, will be charged and collected at the property. This tax does not apply from the 8th night of stay and children 13 and below are exempt. This amount has been determined by the local administration. For further details, please contact the property using the information contained in the confirmation received after booking.
Optional extras
Late check-out can be arranged for an extra charge
Self parking is available for an extra charge
Buffet breakfast is offered for an extra charge of EUR 12 per person (approximately)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


text:
ClassicsOnline Home » BRAHMS, J.: 4 Ballades / 3 Intermezzos, Op. 117 / 8 Piano Pieces, Op. 76 (Kraus)
ClassicsOnline customers will not be able to use their log in to access the new HD site. Please create a new ClassicsOnline HD•LL account to download albums, subscribe to streaming, create playlists and more!


text:
Financial Technology
Follow us on Twitter
Free eNewsletter
Corporate Performance Management
Industry Sectors
Expense Management
Corporate Performance Management
Budgeting, Planning & Forecasting
Governance, Risk & Compliance
Human Capital Management
M&A/ Mergers & Acquisitions
Reality Check
Featured Articles
Free eNewsletter
↓ Financial Communities
Performance Management
↓ Industry Sectors
Expense Management
Performance Management
Budgeting, Planning & Forecasting
Governance, Risk & Compliance
Human Capital Management
M&A/ Mergers & Acquisitions
» Reality Check
» Featured Articles
» Latest News
» Free Enewsletter
» Contact Us
» Media Kit (pdf)
Financial Technology - INDUSTRY NEWS
[February 26, 2013]
Chicago Public Schools Selects Radiant RFID's Virtual Asset Tracker
Austin, Texas, Feb 26, 2013 (PRWeb.com via COMTEX) -- Chicago Public Schools (CPS), the nation's third largest school district serving over 402,000 students, has selected Radiant RFID, LLC to implement Virtual Asset Tracker (VAT), the company's RFID-based enterprise asset management solution that will manage the school district's highly diverse and mobile inventory of more than $450 million in capital and controlled assets.
Story continues below ↓
"During the RFP process, Radiant proved to be the best suited among competitors to solve complex asset management challenges across many campuses and we look forward to working with them as we begin to implement the solution within Chicago Public Schools" said Peter W. Rogers, Chief Financial Officer at Chicago Public Schools.
By automating data collection, RFID technology greatly reduces human effort and error. Radiant is currently working with Chicago Public Schools to replace its current bar code system with an RFID solution for approximately 100,000 assets at 200 campuses while upgrading data visibility district-wide. Radiant's solution will ultimately encompass all 650+ campuses in the district.
VAT, a complete solution consisting of UHF Gen 2 RFID technology and Radiant software, will enable CPS to accurately report expected and exact locations of large numbers of mobile assets, including technology, video, AV and kitchen equipment, and furniture, instruments, and vehicles.
VAT automates detailed reporting of asset location and ownership. The solution will present this data in many formats to all CPS departments, including accounting and finance, information technology, property management, and administration. Users will be able to create custom reports and view system dashboards to make better decisions for the utilization of assets.
Kenneth Ratton, Radiant RFID Executive Vice President, said, "Radiant's solution is specifically targeted at customer like CPS with highly complex tracking problems, extremely large numbers of items, and diverse locations. Having successfully deployed customers such as FBI and Texas Department of Public Safety, covering millions of items worth billions of dollars, we are confident that CPS will realize the benefits of our end-to-end approach quickly." Designed specifically for educators, Radiant's K-12 Solutions encompass IT asset tracking, student attendance reporting, mustering, and bus ridership. They can be deployed as individual solutions or an integrated suite leveraging a single infrastructure investment.
Read the full story at
Back To Financial Technology's Homepage
Financial Technology Related News
UPDATED 1:15 AM EST - Oct 10, 2015
NEC/NetCracker To Discuss Evolving Relationship Between IoT, Cloud and Virtualization at SDN & OpenFlow World Congress 2015
HMG Strategy's 2015 Southern California CIO Executive Leadership Summit to Focus on Leadership in a Time of Profound Change
Research and Markets: 5G Technology Assessment, Market Outlook, and Forecasts 2015 - 2030
Research and Markets: The Future of IT in Education
Research and Markets: The Future of IT in Finance
Research and Markets: The Future of IT in Retail - An End User Perspective, U.S., Europe, and Latin America
MivaTek to Showcase Video Integrated Home Security, Home Safety, Automation and Health Care Solutions and Services at CEDIA
USA Technologies to Exhibit at The Atlantic Coast Exposition 2015, Booth #205
FREE eNewsletter
Financial Tech Featured Editorial
Investors are Turning Their Attention to These Hot Real Estate Markets
Would You Commit to a $70,000 Minimum Employee Salary?
Armanino's Intacct- a Strong Contender for QuickBooks?
Hitachi, RapidMiner Enter into Strategic Partnership
SAP Increases Agility in Finance
View all
Financial Tech Industry Sectors
Expense Management
Corporate Performance Management
Budgeting, Planning & Forecasting
Governance, Risk & Compliance
Human Capital Management
M&A/ Mergers & Acquisitions
Financial Technology RSS
Expense Management
Business Performance Management
Budgeting & Planning
Risk Management
Human Capital Management
M&A/ Mergers & Acquisitions
Money Management
General Info
Technology Marketing Corporation,
800 Connecticut Ave, 1st Floor East
Norwalk, CT 06854 USA
Ph: 800-243-6002, 203-852-6800; Fx: 203-853-2845
General comments: email@example.com. Comments about this site: firstname.lastname@example.com.
Contact us
Technology Marketing Corp. © 2015 Copyright.
Online Communities
Corporate Performance Management
Governance risk and compliance
Industry Sectors
Expense Management
Corporate Performance Management
Budgeting, Planning & Forecasting
Governance, Risk & Compliance
Human Capital Management
M&A/ Mergers & Acquisitions
Other Industries
4G Wireless/WiMAX
Green Technology
Information Technology
Smart Grid
Health Care
Business Video
© Technology Marketing Corp. © 2015
Privacy Policy
Visit other TMC Interactive sites


text:
Your premium GranCanariaGay.com gay guide is back!
We were one of the first gay guides of Gay Gran Canaria back in 2004 and offer you now since April 2015 the first and only GEOLOCATION gay guide for Gran Canaria.
Visit and explore the favorite spots with any device you like and find interesting places near you – and plan where you stay and where to go with the interactive gay Gran Canaria maps with integrated street views.
When are the next gay events in Gran Canaria?