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Northern Carolina hit by strongest earthquake in 25 years
Northern Carolina has reportedly been hit by the strongest earthquake in 25 years, a report said.
The quake measured 6.0 on the Richter scale and struck six miles southwest of Napa, North Carolina's infamous wine country, early Sunday. Several people were injured in the region and historic structures were damaged in downtown Napa, reported CNN.
Almost 160 received treatment for minor injuries at Queen of the Valley Hospital, the report said. However, hospital CEO Walt Mickens could not confirm if all the patients were injured in the earthquake.
The hospital also admitted 13 people for orthopedic issues and medical conditions. Only one patient was in a critical condition by Sunday night.
Glenn Pomeroy, CEO of the California Earthquake Authority, said that the damage in Napa was "fairly significant."
The earthquake has also left 15,000 customers in and around Sonoma, Napa and Santa Rosa without power.
(Posted on 26-08-2014)
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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
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The weekend may be just around the corner, but you still want to impress at your Friday touchbase. Luckily, you've got this plum-and-vanilla striped black shift hanging in your work wardrobe. Lightweight and long-sleeved, this lined, boat-necked dress satisfies your craving for casual-Friday comfort while keeping your look crisp and professional. Slip on some kitten-heeled Mary Janes, pearl earrings, and a simple gold bracelet before you set out for the day, and finish the week feeling fabulous!
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The St. Patrick's Day Parade will be winding its way through downtown Toronto on March 15. The Toronto Paramedic Services and Toronto Paramedic Association will be marching in the parade, collecting non-perishable food donations for Daily Bread Food Bank. This is the second year in the row that they have collected food donations. Last year over 1130 pounds of food was donated, helping provide nutritious food to families in need. This year, they've doubled their goal. Help them raise over a 1000 pounds of healthy food by bringing a non-perishable food donation down to the parade!
Not sure what to donate? Here are some great ideas of food to donate that Daily Bread needs:
- canned/dried beans or lentils
- canned fruit and vegetables
- peanut butter
- canned fish
- tomato pasta sauce
The parade starts from Bloor and St. George at noon on Sunday, March 15. For more information on the parade, click here.


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From our best Christmas cookies to festive Yuletide menus, we've got recipes to help you plan perfect Christmas parties, dinner on Christmas Day, holiday brunches, plus a special plate of cookies for Santa's visit on Christmas Eve.
Comte Cheese Spoon Breads with Roasted Pepper Raisin Jam
Made in individual muffin cups, these spoon breads are cheesy, creamy and delicious, especially when served with Roasted Pepper Raisin Jam.
Upside Down Apple Cake
A bit a cornmeal in the batter adds great texture to this luscious apple cake.
Sweet Tangerine Cake
A not-too-sweet single-layer cake that's a perfect take-a-long to book club meetings, potlucks and casual gatherings.
Lemon-Glazed Pistachio Shortbread Cookies
A tart, crisp cookie from The Good Neighbor Cookbook—ideal for welcoming a new neighbor or gifting to an old friend.
Gussy up guacamole with pungent blue cheese, spicy peppers and creamy sour cream for an unforgettable party dip.
Cranberry Crumble
Fresh cranberries and tart apples combine with sweet dried apricots in a moist buttermilk cake that's perfect for fall and winter holidays.
Rosa di Parma (Filled Beef Tenderloin)
Having company? Try this indulgent stuffed beef tenderloin for special occasions.
Ginger Pot Roast with Ginger Pineapple Compote and Quinoa Salad
Pork and pineapple is a classic combination (think ham and pineapple pizza). The sweet acid of the pineapple takes well to ginger and the spicy notes of the ginger play well off the pineapple.
Lemon Slice-and-Bakes
A shortbread with a subtle lemon twist, these go perfectly with tea or hot apple cider.
Coca-Cola Cake
The one and only Coca-Cola® combines with rich chocolate and vanilla in this delicious cake.
Pomegranate Roasted Leg of Lamb
Pomegranate, balsamic vinegar and rosemary — Mediterranean flavors for roast lamb.
Steamed Cranberry Pudding
This traditional recipe from Tuckaway Farms combines the sweetness of a butter sauce with the tartness of cranberries.


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Riddled with graphic scenes depicting hockey-puck torture and naked actors having sex on top of washing machines, the controversial crime thriller "Running Scared" is a long way from your typical Paul Walker movie. Looking back on the movie now, the affable Southern California heartthrob admits that even he isn't sure he likes the character he plays — and that's precisely why he took on the role.
"He's a bad man," Walker said of low-level mobster Joey Gazelle, flashing a lethal grin. "He's a bad man with a good heart. He does a lot of really dark, very questionable things and doesn't appear to be the nicest guy, but I think he's all justified. He's very loyal to his family, and if things were to get heavy and you found yourself in a lot of trouble, he'd be the type of guy you'd want to have as a friend."
The fast-paced flick begins with Gazelle desperately needing some friends of his own after a weapon used in a botched mob hit goes missing. When Joey's son (first-time actor Alex Neuberger) and his best friend Oleg (Cameron Bright, "Birth") vanish along with the gun, he sets out on a mission to recover them before a Tarantino-esque stable of local cops, mobsters and street thugs introduce him to their weaponry.
For co-star Vera Farmiga, cast as Joey's no-nonsense wife Teresa, the ultra-violent movie similarly represented a chance to get away from reality. "I dislike guns, I really do," the 32-year-old "Manchurian Candidate" actress recoiled. "Words are more powerful than loaded pistols, I think, in the end. [And besides,] look at the havoc that is wreaked when a child gets a hold of it."
"Wayne creates this uneasy, hybrid world where complete menace and grit and insanity meet this whimsical, fanciful comedy," Farmiga added, praising writer/director Wayne Kramer ("The Cooler"). "It's 'Scarface' meets 'Alice in Wonderland,' and it has this incredible fairy-tale quality to it that takes place in this high-octane world."
|Peep the "Into the Blue," "Eight Below" and "Running Scared" star's life and career, in photos.
The phrase "high-octane" doesn't even begin to describe the flick's most unforgettable scene: a sexy encounter atop a washing machine (see "Paul Walker's Internet Sex Clip Isn't Video — It's A Video Game" ). While one might expect such a scene from the writer/director who famously did battle with the MPAA three years ago over the number of thrusts permitted to William H. Macy in "The Cooler," Walker and Farmiga insist that it was them who talked Kramer into the steamy sequence.
The scene begins with the sight of Farmiga's exposed thong riding a few inches above her jeans. "Yeah," Walker laughed, agreeing that it's one of the most memorable film intros in quite some time. "You think?"
"I came up with that idea," the actress said of her unavoidable undergarments. "You have to [have a scene like that], because in the space of 20 seconds, you have to establish for the rest of the movie two people who are adamantly in love with each other. Despite his crookedness, she's in love with her husband. And I wanted to portray that. Even after 12 years, this woman loves her man and vice versa. And so we had 20 seconds to do that, and … you've gotta paint that."
As for the lockjaw-inducing love scene that follows, Farmiga sounds like her character when she credits her love interest with putting forth all the effort. "I have a feeling that Paul Walker came up with that," she laughed.
"Yeah, I did," he giggled mischievously. "I do it all the time, so I thought, 'Hey let's bring a little reality … It's realism. That's what happens. When you're in that situation, it's my wife in the movie, who I'm very attracted to, and I think we have a very good love life and it was appropriate. Especially considering [the violence] I had just been through, I wanted to taste life again."
In stark contrast to that sultry scene is a show-stopper that has Gazelle's face being held down while an evil hockey team takes aim at it. Luckily the sun-drenched leading man — who also stars in current box-office champ "Eight Below" — didn't take as much of a beating while learning to affect a New Jersey accent.
"I can do Vietnamese, Chinese, Japanese," Walker proudly revealed. "You pick up on these things growing up in Southern California; it's all there in front of you. With the East Coast thing, it's more just from watching mobster movies."
Walker added that he worked with a dialect coach while perfecting his "Scared" persona, but that it really snapped into place once he walked on set opposite one of the all-time greats of gangster cinema. "The thing that helped me the most was having worked with Chazz Palminteri," he said of the "Analyze This" and "Usual Suspects" star, cast in "Scared" as a dirty cop. "About a year prior we did a movie called 'Noel' and … to be honest, without that relationship [with Palminteri], I don't know that I would've made this movie. I think he was the one I really needed to just kind of give me that kick in the butt, like, 'Hey man, don't be afraid.' "
Now, with some help from Palminteri, the star is coming to theaters everywhere in a film very unlike your typical Paul Walker movie. But while he may not like his character, he sure does like the performance. "When you're comfortable you relax too much," the star concluded. "You are your best when you're intimidated."
Check out everything we've got on "Running Scared."
Visit Movies on MTV.com for more from Hollywood, including news, interviews, trailers and more.


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Choose a home perfectly suited for you from National Award-Winning
Brendon Homes.
Montage is a condominium community located in Framingham just two miles from the Mass Pike. It's a neighborhood that's tucked away, yet surrounded by every amenity and convenience imaginable: The Natick Mall, Wayland Town Center, Whole Foods and a myriad of restaurants and retail are all just minutes away.
Attached Homes Priced from $450,900
Detached Homes Priced from $529,900
Designed and built by the National Award-Winning Brendon Homes, the homes of Montage at Danforth Green appeal to the most discerning buyers. The craftsmanship and attention to detail has raised the bar in condominium living. We invite you to live beautifully at Montage.


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300+ Rentals · Napa
300+ Rentals · Napa
Welcome to our castle surrounded by vineyards in North Napa. The private bedroom comfortably fits two and has easy access to Highway 29, Silverado Trail, wineries, downtown, restaurants, shops and more! Learn More
It's a very nice, clean, large private suite in a single family home on the first floor. The room is in a 10,000 sq ft., 5 bedroom, 6.5 bath home with a beautiful patio, balcony and swimming pool in a quiet neighborhood. It is our guest room that we have listed and it has a king size bed, armoire and closet with a ensuite full bathroom. Parking in property and wireless internet. Central heat and air conditioning. You will have privacy in our home and we hope you enjoy it. Very quiet vine...
Completely renovated quality 31-foot Airstream in the backyard of the Main Street Farmhouse B&B. Brand new Sealy Posturpedic Full bed, bathroom, kitchenette, couch, dinette, flatscreen TV and wifi. Sorry, NO PETS allowed. Learn More
Talk about Glamping! You can go "glamour camping" right on Main Street in Napa California! This fully renovated 31-ft Airstream has all the conveniences of home. Fully plumbed with water and drain - plenty of water pressure! Beautiful patio/yard area for you to enjoy too. Main Street Farmhouse B&B is a licensed Bed and Breakfast and the price you see stated has the occupancy tax included already for your convenience. There is no deposit required. Continental Breakfast is provided ev...
Our guest suite is located on 5 acres in the beautiful Coombsville AVA! It is on the 2nd floor of a detached garage and is surrounded by vineyards. It is removed from the main house and has a private outdoor sitting area overlooking the vineyards. Learn More
The suite has one queen bed, full bath (shower only), sitting area, balcony and kitchenette. The kitchen has a coffee pot, refrigerator, sink, microwave and comes fully stocked with dishes and utensils. There is also a flat screen TV with full cable service. We will be here to welcome you and provide any recommendations you may have for restaurants, wineries and other local activities. We can also provide you with maps and guidebooks. Located on a country road in a very quiet area in th...
Decked cabin on edge of Napa Creek two miles from center of town with writing desk/breakfast table, queen bed, flat-screen TV, computer and cell phone access, microwave and toaster ovens. Private, scenic, a place to think and create. Learn More
Fully furnished decked cabin on the edge of Napa Creek two miles from the center of town. Eclectic furniture includes a writing desk/breakfast table, a comfortable queen bed, a large flat-screen TV and computer and cell phone access. A mini-kitchen has a microwave oven, a toaster oven, refrigerator, sink and place settings for two guests. The owner's original watercolors decorate the walls. The location is scenic, quiet and private. Deer can be seen at any time of day. There's a path to the...
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Charming Bungalow attached guest suite with private entrance in desirable Alta heights neighborhood. Near downtown and Oxbow (1 mile). Easy access to 29 and Silverado trail wineries. 15 min to Yountville. Learn More
Experience Napa at our quaint attached guest suite with private entrance - 1 bedroom, separate kitchenette and living space, bathroom and access to back patio. We also include 2 bikes with this rental. This home is in the Alta Heights neighbourhood of Napa - near downtown Napa and Oxbow. Walking/ Biking distance to Oxbow, restaurants, gourmet eateries, tasting rooms, wineries, etc. - Off of Silverado Trail for easy access to wineries such as Mumm, Frogs' Leap, Luna, Pine Ridge, Contessa,...
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Napa neighborhoods/streets are very diverse regarding types of houses, parking, etc. The Farmhouse sits on beautiful part of Main Street with great parking. We recommend to street view the address you are considering prior to making a reservation. Learn More
ALSO SEE "Main Street Farmhouse 2 Bdrm + Bath" if you need up to 6 people and "Cottage at Main Street Farmhouse" AND "Farmhouse Silver Cloud" (separate locations on Airbnb) for availability. For groups of 6, please reserve this room and the other two rooms on "Main Street Farmhouse 2 Bdrm + Bath". Charming renovated farmhouse built in 1880 on Main Street! Fifteen minute walk to downtown restaurants and Oxbow market. Comfortable bedroom(s) featuring hotel quality queen beds with ultra co...
Welcome to our castle surrounded by vineyards in North Napa. The private bedroom comfortably fits two and has easy access to Highway 29, Silverado Trail, wineries, downtown, restaurants, shops and more! Learn More
It's a very nice, clean, large private suite in a single family home on the second floor. The room is in a 10,000 sq ft., 5 bedroom, 6.5 bath home with a beautiful patio and swimming pool in a quiet neighborhood. It is our guest room that we have listed and it has a king size bed, armoire and closet with a ensuite full bathroom. Parking in property and wireless internet. Central heat and air conditioning. You will have privacy in our home and we hope you enjoy it. Very quiet vineyard set...
A 1950's bungalow home on a quiet street with 2 rooms for rent $125 each 2 people per room. Both rooms have a queen size bed and share a bathroom that has double shower. Breakfast provided from our garden and eggs from our chickens. No extra guests. Learn More
A one bedroom cottage that sleeps 2 with a king size bed and large sectional couch ( sleeps 2 ). Kitchen is stocked with snacks, coffee, tea and waters. Backyard BBQ. Parking off street. Walking distance to downtown. Easy and convenient to wineries. Learn More
Quiet and convenient to shopping, winery's and restaurants. We are located just about a 2 min drive from Downtown Napa where you will find shopping , dinning and entertainment. If you would like to walk it will take you about 15 - 20 min from the house . Safety information Smoke alarm between bedroom and bathroom as well as carbon monoxide detector and fire extinguisher located in the linen closet with a small first aid kit. Hospital directions and evacuation information is located in...
BEST LOCATION- ONE BLOCK TO RIVER WALK, CAFES, SHOPS- KITCHEN - DECK -SECURE GARAGE PARKING- READY TO ENJOY... PRIVATE LUSH YARD / BBQ...LARGE HD TV, COFFEE MAKER- DESK, WALK OVER BRIDGE TO OXBOW INDOOR MARKET- 10 MINUTE DRIVE TO YOUNTVILLE Learn More
We welcome you for your enjoyment while you are staying with us . Sit out in the garden and enjoy. YOUR OWN SPACIOUS 1 BEDROOM - CONVENIENTLY LOCATED - TWO NIGHT MINIMUM This will accommodate 4 PLEASE leave a note if you feel we need anything else Feel free to enjoy the gardens, the lemon trees and avocado tree Washer and dryer are off the rear deck I WILL BE AVAILABLE FOR QUESTIONS WALK TWO BLOCKS TO CAFES, WINE BARS, GREAT RESTAURANTS, PREMIER SHOPS, RIVER WALK, SWEET SHOP AND PIES...
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Welcome to the Cottage! Check in is 3:00 or later, drive down the driveway and park across from the Cottage. Call or text when you are about 30 minutes from arriving. Enjoy Napa! Learn More
Fully renovated 600 square foot cottage located behind the popular Main Street Farmhouse B&B! Two Sealy Posturepedic queen beds and the most comfortable bedding and linens to sleep on after a wonderful day touring Napa Valley. Full bath and a kitchen with refrigerator, microwave, toaster oven and electric griddle. HD TV and Wifi. Plenty of peaceful outdoor seating area to relax in and enjoy on this incredible historic half acre on Main Street! 15 minute walk to downtown Napa and Oxbow M...
- Private Entrance - Deck - Close to wineries - Close to local market - 10 mins (drive) to Downtown Napa - 15 mins (drive) to Sonona Plaza - Queen Size Bed Learn More
Sadly you won't see much of us as we're busy. We each run our own business and are busy with family activities and life! It's pretty quite around here and we are about 3 or so miles to the "bustling" downtown Napa area. We're close to some great down valley wineries with quite a few within 10 minutes drive! It's best to have your own car or if you're going wine tasting book a limo or driver! This is a self-contained unit in our house with your own entrance.
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Vino Bello is a very luxurious highly rated timeshare condominium resort on Tripadvisor, with a free daily shuttle to and from downtown! Learn More
VINO BELLO RESORT is a premier all-condominium timeshare resort adjacent to the world class Meritage Resort & Spa, with privileges at Meritage's state-of-the-art Spa Terra and the Estate Wine Cave and Meritage Wine Tasting Bar. The resort also has a free daily shuttle for guests that runs to and from downtown Napa every 45 minutes between 4:00pm and 8:30pm, and upon request between 8:30pm and 10:30pm. Stay in a STUDIO SUITE (kitchenette), with top of the line luxuries. Note that the reso...
Awesome house; walk downtown. Recently remodeled. Brand new gourmet kitchen with island range. Hardwood floors. Marble bathroom with frame-less glass shower. New furniture and mattresses. Private back yard with outdoor dining. NFL Sunday Ticket. Learn More
2 Bedrooms. One King bed. One full bed. One set of bunk beds. All new mattresses (comfortable!) .
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The guest room in my clean and comfy house is decorated in period furnishings with a vanity for getting ready in the morning. You have access to a private bath. The yard includes hot tub, dartboard, fire pit, hammock and BBQ. Bed is full size. Learn More
My home is located in South Napa with easy access to downtown Napa (3mi), Sonoma and up valley attractions. You will have access to guest room and bath, all common areas and backyard. I have a cruiser bike, a tandem bike and a mountain bike that you may borrow. My neighborhood lies on the edge of the Carneros wine appellation, which is famous for Pinot Noir. I'm less tan a mile away from both Hwy. 29 and Hwy. 12 which offers easy access to Sonoma or Napa. If you like to run or walk in th...
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Inside the heart of wine country, enjoy your beautiful home away from home! Unwind in your own Napa home and enjoy the valley like a local! With a backyard perfect for entertaining. Learn More
A comfortable one bedroom guest house. The full private guest quarters are yours with a Cal-King bedroom, full closet, dresser, etc. full bathroom with shower, living room with large flatscreen tv and full kitchen with eating area. Air mattress available upon request if trying to sleep additional guests. Additional blankets and pillows for couches also available. Your own private unit with Cal-king bedroom, full bathroom, separate kitchen, living area with full kitchen, tv and internet. F...
Walking distance to all the downtown bars and restaurants, come stay at my Napa apartment. The building is a house that was converted into 4 units. I have a queen sized air mattress to be set up in the living room. Lots of windows and natural light. Learn More
You can walk everywhere! I do have a dog. She is a husky/shepard mix. Very friendly and playful :-)
We are located in one of the hidden country gems of Napa in the Coombsville appellation, just 10 minutes from downtown. This is ideal for those are are looking for pure relaxation in a country setting. Extremely quite, private and serene. Learn More
The Cottage is spacious and very comfortable. You have your own privacy as the cottage is situated away from the main house. You can roam around our 4-acres of ancient oak groves and meadows. Grab a blanket and a bottle of wine and enjoy the amazing stars twinkling in the sky and the orchestra of crickets and frogs, truly remarkable. You can come and go at your leisure with a secure gate at the entrance and door key code on the cottage. We are more than happy to suggest wineries to visi...
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A new study shows that monitoring levels of exhaled nitric oxide in adolescents with asthma and adjusting treatment accordingly does not improve the course of their disease.
The study was conducted by the Inner City Asthma Consortium (ICAC), which is funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). The Sept. 20 issue of The Lancet reports the ICAC findings.
Approximately 550 adolescents in 10 cities across the United States participated in the study. It was designed to examine whether in addition to treating asthma based on national guidelines developed at NIH, measurements of exhaled nitric oxide would allow even better control of the disease. This was the largest study to date testing exhaled nitric oxide as a biomarker for asthma management.
Asthma is a chronic disorder of the airways that affects approximately 9 percent of children under age 17 in the United States. The causes of asthma are still unknown, but allergens, air pollution and infections can provoke its symptoms, which include wheezing, chest tightness, shortness of breath and coughing. Asthma symptoms occur when the tissues of the lungs become inflamed and the muscles in the airways contract, making breathing difficult. One measurable marker of asthma-related inflammation is high levels of nitric oxide (NO) in the breath; it is known that the higher the exhaled NO, the greater the inflammation of the lungs. Equipment is now available to easily measure exhaled NO. Widely used asthma treatments, such as inhaled corticosteroids, reduce both lung inflammation and exhaled NO. Exhaled NO would potentially be a good biomarkera measurable feature of a disease that indicates its severityof asthma inflammation.
"A biomarker of airway inflammation could be a useful clinical tool for gauging medical needs and clinical responses in asthma patients," says Anthony S. Fauci, M.D., director
|Contact: Julie Wu
NIH/National Institute of Allergy and Infectious Diseases


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about the stylebabyLOG
Hi Shawna! You might recognize my name or my husbands name (Dathan). We have ordered the StyleberryLog from you multiple times for friends and once for ourselves. I was wondering if you are going to sell them again or if maybe you had just one left around or possibility a store that has some left to buy?? I am due with baby #3 in 5 weeks and I know how much of a lifesaver it was last time (!!!) so I was hoping to be able to have one to use this time as well! Thanks!
[…] about the stylebabyLOG […]
Hi, this seems like a very ghood idea!! How much is shipping to Singapore please? amd how many weeks/sheets is the log? a year?
Any chance you are making one of these in blue? Thank you!
[…] Mommy brain + labor/birth trauma= not so easy to be all organized and remembering stuff. great little log for moms (and dads!) who want to have a good picture of their baby's patterns. I wish I had […]
I need another baby now so I can order this! LOL
How can I purchase these in person? I live in your area. I have a couple of baby showers coming up and these would be great gifts! You mentioned Market Days but I'm not familiar with that. I'm so happy to have stumbled upon your blog today…lots of great local resources as I'm new to the area!
Hi! I'm trying to order one as a gift but where can I put the recipient's address?
[…] of joy on the way perhaps? Well, the fabulous Shawna of StyleBerryBlog just recently released the StyleBaby Log. It's the perfect way of keeping track of everything your newborn does. From those drowsy […]
[…] She also just launched a new product: StylebabyLOG […]
Yay! So excited for you to get this out there and so excited for all of us who get to use it! Congrats on your accomplishments!!
I LOVE this!!!! My lactation consultant said "why do you track?". I track because I've lost my mind! I stopped tracking because she made me think I didn't need to…HUGE mistake! I'll be getting one once baby #2 is coming along.:-D
WOW! I know you've put a lot of time into this and it truely shows! You are a true inspiration – these look amazing!
You are such an amazing woman, I LOVE it!!
[…] What is the stylebabyLOG? […]
Thanks Shawna!
You are so clever!!! Love this and want to get some for new
AWESOME!!! Quick odd question, how did you take these photos? White backdrop???
Fantastic job! I will be placing a few orders for some pregnant girlfriends, for sure.
Yup, put me on the want list! I should have had this with my first, could not figure out a good way to keep track of all this in one place! Of course I didn't know I'd want to keep track of all of it until after I had my baby and then i didn't have the time or where-with-all to make one up. Hope you ordered a big box of these! They look beautiful.
Can't wait. Do they have a price yet? I have several babies I need to buy for. Oh, and then there's ME! Hmmm…are these going away? I want one for future kiddos.
Oh I can see this coming in handy for the soon-to-be-born baby over here. Since I have to leave him in my mothers care after 8 weeks this will be awesome to have.


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Miller PipeWorx (230/460 V) Welding System (951381)
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If Neils Miller doesn't have a statue in Appleton, Wisconsin, he should. You'll be hard pressed to find someone who has had a larger impact on the welding industry than Mr. Miller. Back in 1929, he saw a need for a small, affordable arc welder that would operate on the type of electricity readily available in rural Wisconsin. Using American ingenuity, he cobbled together scrap metal, core and coil materials and hammered out that first welder in his basement. Six short years later, Miller Electric Mfg. Co. produced an industry-changing industrial welder and the rest is history.
Throughout the 40's, Miller's machines powered war efforts in the shipyards and defense plants. In the 50's, Miller played a key role in the construction of most major planes, jets, fighters and missiles. Companies like Boeing, Cessna, Lockheed, Douglas all used Miller machines in their factories. The 1970's brought the introduction of the Millermatic machines; the first power source with a built-in wire feeder.
Today, Miller Electric continues their dominance in the marketplace with machines like the Millermatic 211 and the Dynasty 200 DX, Auto-darkening welding helmets, and the Diversion 180 AC/DC TIG Welder. Miller's full line of welding machines and welding accessories give their loyal customers plenty of reasons to "Bleed Blue."


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- 459Promote
Art Print
i broke an promise to myself to never make one of these stupid postersby Gemma Correll
Collect your choice of gallery quality Giclée, or fine art prints custom trimmed by hand in a variety of sizes with a white border for framing.
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Fans never want to see their team have a bad day. Fans want to see their team play at peak efficiency every game. They want to see high energy and performance at the 99th-percentile level every week.
But that's not possible. You don't always play at your best every week. What made Bud Grant the ultimate football leader was that, more than any other coach in football, he was able to get his Vikings teams to play hard and smart almost every week. He never got overly excited, and I never once saw him down. He was consistent in his approach, and it led to an unusually successful run.
Last week, the Vikings certainly didn't play at their best. Up against the Tampa Bay Buccaneers, the Vikings struggled from the beginning of the game and the score very quickly got out of hand.
But people don't take into account that your schedule is not just about whom you play, but when you play them. I worried that last week's matchup could be a trap game in last week's column because Tampa Bay is playing probably as well as it will play all season. The Bucs have generated more than 400 yards of offense in each of the last three games now, after never getting close to that number in their first four games.
And I suspect that at the end of the year we will see that last week's game was their best of the entire season! The Vikings' bad day didn't help matters, but it was a trap game because a number of things came together in Tampa Bay's favor.
Make no mistake: This Minnesota team is good enough to compete against anybody and make the playoffs.
Just a few weeks ago, lots of people were ready to dismiss the Denver Broncos. They were 2-3 and had lost to the Atlanta Falcons, Houston Texans and New England Patriots. Denver losing fit into the narrative that Peyton Manning just didn't have it anymore after his surgeries. Fast forward to today, and Denver is a favorite in the AFC. Denver fans are ecstatic because Peyton looks great, the defense is great, the running game is great -- and that's just because of wins over San Diego and New Orleans and a 4-3 record overall.
If people want to write off the Vikings now, they're crazy. The team has shown it can play on a level with anybody in the league, and it will be in the hunt until the season's end. The last six weeks of the season -- with matchups against the Chicago Bears, Green Bay Packers and Texans -- will ultimately determine the fate of the 2012 Vikings.
This week's matchup against Seattle will be tough. The Seahawks are a different team at home than on the road. Their rookie quarterback has exceeded everyone's expectations, and they play strong defense, especially in the secondary.
I suspect most people will predict the Vikings to lose. But I think the Vikings will win. A big reason is that quarterback Russell Wilson has not yet seen a defensive end like Jared Allen. But another reason is that this Vikings team is very resilient. There are great players on both sides of the ball, and there is solid leadership in the organization from top to bottom. That's what you need to bounce back from a tough loss, and that's what the Vikings will showcase Sunday afternoon.
Fran Tarkenton is Minnesota Vikings analyst for TwinCities.com and the Pioneer Press. He is a former Vikings quarterback and a Pro Football Hall of Fame member. He also is an advocate for small businesses and the founder of OneMoreCustomer.com.


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Day 2 of the NFL's free agency frenzy began with another bunch of signings. Even Ray Lewis got a new deal _ with ESPN.
Kansas City remained busy Wednesday by adding cornerback Dunta Robinson, late of the Falcons, to the three free agents it signed the previous day when the marketplace opened. The Chiefs, who have the No. 1 pick in next month's draft after a 2-14 season, agreed to deals with tight end Anthony Fasano, defensive tackle Mike DeVito, and quarterback Chase Daniel on Tuesday, when they also finalized the trade with San Francisco for starting QB Alex Smith.
After hiring Andy Reid as coach and John Dorsey as general manager, the Chiefs signed wide receiver Dwayne Bowe and punter Dustin Colquitt to long-term deals and franchised left tackle Branden Albert.
Cleveland, another NFL also-ran, was just as active, agreeing to terms with linebacker Quentin Groves and tackle Desmond Bryant to further bolster a defense that added Ravens linebacker Paul Kruger hours after free agency began.
"With the additions of Paul and Desmond, we believe that we have significantly improved our defense overall, particularly our front seven," Browns CEO Joe Banner said.
Kruger is one of many Super Bowl winners to leave the Ravens, including hard-hitting safety Bernard Pollard, who was released Wednesday. The biggest loss for Baltimore was an expected departure: Lewis announced in early January that he was ending his 17-year career. Then he led the Ravens to the championship.
On Wednesday, he joined ESPN as a studio analyst _ an intense one, no doubt.
"I'm ready to bring the same level of passion to this next phase of my life as I brought to the field during my years as a player," Lewis said.
Baltimore signed defensive lineman Chris Canty, offensive lineman Ramon Harewood and running back Damien Berry.
Also Wednesday:
_Chicago released tight end Kellen Davis after signing Martellus Bennett away from the Giants on Tuesday to replace him.
_The Giants signed 11-year veteran place kicker Josh Brown, who joins former Cowboys kicker David Buehler on the roster and apparently indicating free agent Lawrence Tynes won't be back. Tynes has made winning field goals in to NFC championship games in overtime and the Giants went on to win the Super Bowl in those seasons.
_Pittsburgh found its backup to QB Ben Roethlisberger in a Steel City native, Bruce Gradkowski. The 30-year-old Gradkowski is 6-14 as a starter with Oakland, Cleveland and Tampa Bay. He spent the 2011-12 seasons with the Cincinnati Bengals, appearing in five games.
Pittsburgh also released oft-injured offensive lineman Willie Colon.
_Jacksonville released receiver Laurent Robinson, the latest high-priced player let go as part of the team's rebuilding project. Robinson signed a five-year, $32.5 million free agent-contract last season before missing considerable time with concussions.


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Supernormal Goal for Proximal Femur Fracture
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- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This is an observational pilot study of supernormal oxygen delivery goal for patients with proximal femoral fracture.
Femoral Fractures
Procedure: Supernormal oxygen delivery goal therapy
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
|Official Title:
|Supernormal Oxygen Delivery May Not be a Valid Goal for Patients With Proximal Femur Fracture. An Observational Pilot Study
- Oxgen delivery index [ Time Frame: At the end of 4 hour goal-directed therapy ] [ Designated as safety issue: No ]To attain a improved oxygen delivery index at the end of 4 hour goal-directed therapy
- Hear rate augmentation [ Time Frame: Day 1 ] [ Designated as safety issue: Yes ]
- Hemodynamic response [ Time Frame: Day 1 ] [ Designated as safety issue: No ]Including stroke volume, cardiac index, base excess, lactate, hemoglobin, and urine output.
- fluid volume administrated [ Time Frame: intraoperatively ] [ Designated as safety issue: No ]
- Length of hospital stay [ Time Frame: Day 30 ] [ Designated as safety issue: No ]
- Postoperative morbidity [ Time Frame: day 5 ] [ Designated as safety issue: Yes ]
|Estimated Enrollment:
|Study Start Date:
|August 2014
|Estimated Study Completion Date:
|June 2015
|Estimated Primary Completion Date:
|April 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
Supernormal oxygen delivery goal therapy
Patients will be aged over 70 yr and weight over 35 kg, and undergoing proximal femur fracture (PFF) surgery under peripheral nerve block and laryngeal mask airway anesthesia.
Procedure: Supernormal oxygen delivery goal therapy
A 10% increase in stroke volume (SV) after fluid challenge (5 ml/kg) with Ringer's lactate solution will be deemed positive. Oxygen delivery will be check when fluid challenge becomes negative. If oxygen delivery index (DO2I) can not be greater than 600 mL/m2, then dobutamine will be started at a dose of 2.5 μg/kg/min and increased by the same increment every 20 minutes until the described target is reached or until a maximal dose of 10 μg/kg/min is given. Dobutamine is decreased in dose or discontinued if the heart rate is above 100 beats per minute or shows signs of cardiac ischemia. Blood transfusions will be used to maintain a hemoglobin concentration over 8mg/dL.
Detailed Description:
Augmentation of oxygen delivery using fluids with or without inotropes has been shown to improve surgical outcome in high-risk patients. Patients with proximal femoral fracture are considered high risk. However, most of this cohort elderly patients have poor cardiovascular condition and may not achieve the oxygen delivery goal. We will perform an observational pilot study whether the supernormal oxygen delivery is a valid hemodynamic goal for patients with proximal femoral fracture.
|Ages Eligible for Study:
|70 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Patients will be aged over 70 yr and weight over 35 kg, and undergoing proximal femur fracture (PFF) surgery under peripheral nerve block and laryngeal mask airway anesthesia.
Inclusion Criteria:
- Patients aged over 70 yr
- Weight over 35 kg
- Underwent proximal femur fracture (PFF) surgery under peripheral nerve block and laryngeal mask airway anesthesia.
Exclusion Criteria:
- Patients who could be harmed due to the treatment (ongoing myocardial infarction, chronic dialysis)
- Monoamine oxidase inhibitor use within the last 14 days
- Pathological fractures and conditions
- Inability to give informed consent(as judged by a research team member)
- Anticipated difficulties obtaining data during the first postoperative year (as judged by a research team member)
Please refer to this study by its ClinicalTrials.gov identifier: NCT02194101
|Contact: Xiangcai Ruan, MD, PhD
|Contact: Jingwen Guo
|China, Guangdong
|Guangzhou First Municipal People's Hospital
|Guangzhou, Guangdong, China, 510180
|Principal Investigator:
|Xiangcai Ruan, MD., PhD.
|Guangzhou First Municipal People's Hospital,Guangzhou,Guangdong,China,510180
|Responsible Party:
|Xiangcai Ruan, Vice-Chair, Guangzhou First Municipal People's Hospital
|ClinicalTrials.gov Identifier:
|NCT02194101 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 14, 2014
|Last Updated:
|July 16, 2014
|Health Authority:
|China: Health and Family Planning Commission of Guangdong Province
Keywords provided by Guangzhou First Municipal People's Hospital:
oxygen delivery
proximal femoral fracture
goal-directed therapy
Additional relevant MeSH terms:
Femoral Fractures
Fractures, Bone
Leg Injuries
Wounds and Injuries
ClinicalTrials.gov processed this record on October 09, 2015


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Community Portrait: Downtown shop owner finds golden opportunity in USBy: Michael Kirby
Auburn resident Ben Asgharzadeh arrived in the United States in 1969 with his wife, $100 in his pocket and one suitcase.
He did not know English and knew no one. He had great hope, though, and a strong desire to live and succeed in a land that allowed personal freedoms and a government that permitted and encouraged anyone with a dream to achieve it.
"I wanted my freedom," Asgharzadeh said.
He landed in New York City on the day before Thanksgiving, and on the day after applied for a job at IBM headquarters in the New York area. Even without being able to speak English, Asgharzadeh was able to impress his future employers that he had skills that could benefit their corporation and that he was determined to live, work and succeed in America. He was hired on the spot.
"I never had help from the government or anybody else and after two weeks on the job I bought a house in New York," he said.
Asgharzadeh was born in Azerbaijan, a country in Eastern Europe that was incorporated into the Soviet Union in 1920 and did not regain its independence again until 1991.
The Azerbaijan government educated Asgharzadeh as a mechanical engineer, because Asgharzadeh possessed a photographic memory, a very valuable tool for obtaining new technology for his country. He then worked for the government as a mechanical engineer, but after a time in government service he immigrated to America to pursue his dreams.
"I had applied for a green card before I came and it took two years to receive," he said.
He began a very successful 20-year career with IBM and retired only because of a series of back surgeries that made it very hard for him to work. "My health forced me to retire," he said.
After retiring in 1989 at age 46, Asgharzadeh moved his family, wife and two boys to Roseville for a change.
"My doctor said a warmer climate would be better for my back and I chose California," he said.
Tragedy struck his family within two weeks of moving to their new home. Asgharzadeh's wife, Francis, and her sister were killed by a drunken driver on Sunrise Avenue. The driver was in a stolen car and received a three-year prison sentence for the crime.
The tragedy was very hard on Asgharzadeh, and extremely difficult for their eldest son, David, who was very close to his mother and 18 years old when his mother passed away. Asgharzadeh is a very outspoken advocate against drunken driving.
In September, Asgharzadeh publicly challenged the return of the Black and White Affair, a Chamber of Commerce fundraiser held downtown. He was concerned about attendees drinking and driving.
After his wife's death, Asgharzadeh did nothing for a year.
He was an avid Swarovski crystal collector and, looking for a dealer in the area, he found the Golden Swann in Auburn and met Margareta Swann. They became good friends through their association and married in 1995. They moved their jewelry store to a larger storefront.
"We expanded and we have become one of the largest dealers for Swarovski in the United States," he said.
The Golden Swann is also an authorized dealer for other collectibles, including Giuseppe Armani and Lladro porcelain and ceramic figurines. The Golden Swann also is a full service jewelry store.
Asgharzadeh and Swann are very involved in the Auburn community helping with many local projects.
Asgharzadeh speaks four languages and is a proud, patriotic American, becoming a citizen in 1978.
"I took a big gamble to come here, but I wanted to accomplish my goal," Asgharzadeh said. "I became a successful man here, and was given a chance to grow in this country. Nobody held me back. This could not have happened in any other country."


text:
Monday, March 5, 2012
© Copyright 2015 Clayton News Daily
Two former bank employees have surrendered to local authorities, following a lengthy investigation into allegations that they defrauded customers, according to Henry County police.
Ollie Latasha Height, 33, of Covington, and Tonie Jeanette Holcombe , 44, of Stockbridge, are charged with 10 counts of financial identity fraud, each.
Henry County police have been investigating the pair since July of 2011, according to Police Sgt. Joey Smith. He said managers at the unnamed banking institution informed the police of the identity of the suspects.
"Both were employees of a financial institution who provides small personal loans," said Smith. "Management was made aware that some customers' information had been compromised. We have not disclosed the institution's name, until all affected parties, or customers have been properly notified. Many customer accounts were compromised, but the suspects were only charged with 10 counts of actually obtaining funds from 10 accounts at this time."
Holcombe turned herself into the Henry County Jail, on Feb. 29, said Sheriff's Maj. Jeff Norman. She appeared in Magistrate Court, March 1, and her case was bound over to Superior Court, Norman said.
Height surrendered to jail authorities on March 1, and her case was bound over on March 2. Both suspects have been released from the jail on bonds of $7,500 each.
More like this story
- Details unfold in Henry ID fraud case ( November 19, 2010 )
- Police hunting members of stolen-checks ring ( May 18, 2010 )
- Suspects surrender in Henry card-fraud case ( November 13, 2009 )
- Hampton woman indicted in bank fraud case ( August 8, 2009 )
- Henry Police investigating identity-fraud case ( April 16, 2010 )


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Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Vasquez et al. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs.
See research article: http://www.biomedcentral.com/1752-0509/4/58/ webcite
Cancer is a disease of uncontrolled cell growth in which cells acquire genetic alterations that allow them to proliferate outside the context of normal tissue development. In the evolution of this transformation, cells acquire mutations that confer selective advantages for the growth of the tumor. Genetic alterations in many of the known oncogenes are selected to adapt cellular metabolism to meet the requirements of rapid cell proliferation as well as autonomous growth and survival in an environment absent of contact with extracellular matrix (Figure 1). Accumulating evidence indicates that almost every known oncogene regulates downstream targets that are directly connected to metabolic regulation [1]. A detailed biochemical and systems-level understanding of precisely how oncogenes rewire metabolism is essential to understand tumor biology, but concomitantly requires an assessment of the metabolic adaptations required to support the proliferation of cancer cells. Understanding the consequences of this differential metabolism requires a thorough analysis of glucose metabolism and its relation to energy production in cancer cells.
Figure 1. Cell-autonomous control of growth and metabolism are acquired upon cell transformation by mutation. Cells in a normal tissue (left-hand diagram) are constrained in their growth by their environment (depicted as green lines). During the development of a tumor (right-hand diagram), cells acquire mutations that allow growth outside the context of normal tissue development. As a result, metabolic pathways are reorganized and metabolism is altered to allow for cell-autonomous growth.
In a majority of tumor types, an enhanced rate of glucose uptake is observed and serves as a reasonable starting point for understanding differential metabolism in tumors. Otto Warburg's initial observation that tumors often metabolize relatively large quantities of glucose predominantly through a fermentative-like metabolism, resulting in lactate production in aerobic conditions (termed aerobic glycolysis), provided the phenomenological foundation for studying altered metabolism in cancer [2]. Rapid progress is being made towards a molecular understanding of why lactate production from glucose gives cancer cells a growth advantage. Paradoxically, cells that achieve high rates of aerobic glycolysis often show relatively small changes in the rate of oxygen consumption in response to changes in glucose uptake; that is, oxidative catabolic flux through the Krebs cycle leading to mitochondrial ATP generation is somewhat independent of glucose metabolism [3].
Alternative metabolic fluxes support the Krebs cycle and mitochondrial ATP production
Catabolic pathways involving the oxidation of material other than glucose in the Krebs cycle are also involved in cancer cell metabolism. For example, glutamine flux into the Krebs cycle has been directly observed in cancer cell lines and appears to be in part regulated by expression of MYC and TP53 (p53) - two of the most common cancer-associated genes [4-6]. Additional amino acids such as arginine and glycine, and metabolic intermediates such as fatty acids, can also be metabolized by mitochondrial pathways in certain contexts. These metabolites have transporters to deliver them into cells and are present in sufficiently high plasma concentrations to support their use in catabolic metabolism in mitochondria [7]. In addition, many of the anabolic products that stem from intermediates in glycolysis can ultimately flow into the Krebs cycle, resulting in a bypass of the generation of pyruvate - the end product of glycolysis. This type of glucose metabolism avoids metabolic activity involving pyruvate kinase and pyruvate dehydrogenase, which are typically inhibited in cancer cells [8]. These alternative pathways present many opportunities for additional stages of regulation in the decision to commit carbon flux to anabolic versus catabolic metabolism, and more research is required to understand the origins and tumor specificities of Krebs cycle flux.
ATP requirements in tumor cells
Aerobic glycolysis is considered a relatively inefficient way of producing ATP, as the alternative catabolic fate of glucose via oxidation in the Krebs cycle and donation of electrons into the electron-transport chain can generate 15 to 20 times as much ATP per unit of glucose. A recent study by Vazquez et al. [9] used a reduced flux-balance model to suggest that synthesizing ATP from glucose through aerobic glycolysis is the optimal ATP-generating strategy when a cell is limited by its capacity to maintain enough mitochondrial mass to support sufficient flux through the electron-transport chain. Whether fermentation is an optimal ATP-generating strategy is unclear; however, there are several lines of evidence that suggest that tumor cell proliferation is not limited by ATP availability.
For mammalian cells, calculations suggest that most of the ATP generated is consumed in basal cellular processes such as the maintenance of concentration gradients through ion pumps and active transport using molecular motors. A simple calculation shows that biosyntheses are not a major source of ATP consumption in tumor cells [10]. As shown in Figure 2, ATP requirements for maintenance and proliferation can be plotted as a function of cell doubling time. For cells that divide on the order of minutes, most of the ATP is used for cell growth. However, for cells that divide on the order of days, such as those in tumor tissue, almost all the ATP is used for cell maintenance. One possible source of confusion about ATP generation in tumor cells is that the apparent lack of demand for ATP in cell proliferation is in contrast to bacteria and other unicellular organisms. These microorganisms undergo rapid cell division on a time scale of minutes and it is estimated that most of their ATP is used for biosynthesis. In all, the calculations suggest that the Warburg effect may not be related to a cell's optimal ability to generate ATP. Furthermore, as we discuss next, ATP hydrolysis can be a limiting factor required to support high rates of glycolysis.
Figure 2. ATP requirements in cell maintenance and division. Using a model based on differential equations for growth rates [10], the fraction of ATP, fATP, consumed for biosynthetic (red dashed line) versus maintenance (black dashed line) purposes in cells is plotted as a function of doubling time in days. Typical doubling times for unicellular organisms such as Escherichia coli and Saccharomyces cerevisiae are shown, as well as for typical cancer cell lines (HeLa) and solid tumors.
Stoichiometric consequences of high rates of glycolysis
The stoichiometry of glycolysis imposes chemical constraints when high fluxes of glucose occur. Consider the overall chemical equation for conversion of glucose to pyruvate via glycolysis:
From the equation, it is clear that glycolysis is not possible without sufficient regeneration of ADP and NAD+. The reduction of pyruvate to lactate by lactate dehydrogenase is the most ubiquitous mechanism known for converting NADH back to NAD+, and this activity balances the very high rate of glycolysis observed in most cancer cells. Efraim Racker noted the problem of stoichiometric ADP availability and postulated that large fluxes through yet to be characterized ATP-coupled hydrolysis reactions were required to balance the cellular glucose uptake rates found in tumors. Futile cycles, more conveniently directly coupled to glycolysis, that hydrolyze ATP were believed to be required to balance high glycolytic flux [11]. One now established example of a futile cycle in glycolysis involves a shunting step in which fructose 6-phosphate (F6P) is phosphorylated to form fructose 2,6-bisphosphate, which is then dephosphorylated back to F6P, resulting in net ATP hydrolysis. Attention has recently been paid to the cancer specificity of these reactions and some studies suggest that the enzyme activity responsible may be differentially regulated in some cancers [12]. Other ATP-consuming futile cycles in central carbon metabolism may yet be discovered.
Growth advantages of aerobic glycolysis
Although aerobic glycolysis may, by virtue of stoichiometry, be necessary to support high rates of glycolysis, the advantages of this process for tumor cells are complicated to understand. Cell-autonomous effects of lactate secretion are likely to confer advantages on tumors. Lactate may enhance the invasiveness of tumor cells by disrupting normal tissue architecture as well as promoting an environment with reduced pH to evade tumor-attacking immune cells.
A complementary teleology suggests that maintaining high rates of glycolysis is required to reconfigure metabolic pathway fluxes to achieve more efficient anabolic metabolism and cell-autonomous growth. One speculation is that a movement of pathway fluxes towards anabolic metabolism can arise from the effects of differential ATP hydrolysis and redox balance that originate from the demands of the stoichiometry shown in the equation above. These differential pathway fluxes are likely to be dependent on tumor type since different oncogenes are used to regulate different anabolic fluxes.
Cancer cells are limited in their growth by the availability of carbon skeletons needed to produce new proteins, nucleotides and lipids [13]. Furthermore, the reducing equivalents in the form of NADPH required for reductive biosynthesis derive from pathways that are orthogonal to ATP-generating pathways. Multiple solutions to the problem of obtaining sufficient carbon material and reducing equivalents are obtainable, and probably depend on the genetic context of the tumor and its microenvironment. A comprehensive understanding of how NADPH is generated and used in cells, and the predominant anabolic carbon fluxes stemming from glucose uptake, will help to parse the molecular consequences of aerobic glycolysis.
Because of the complexity of cancer metabolism, a better understanding will ultimately require the use of mathematical models. This improved understanding will then allow intervention in the metabolic pathways responsible for tumor cell metabolism. Exploiting these tumor-specific properties presents opportunities for therapeutic intervention in tumor development. The pharmacological targeting of enzymes that regulate this restructured metabolism has recently shown some promise in preclinical studies [14].
We would like to thank Cynthia Clower, Edouard Mullarky, Gina DeNicola, Matt Vander Heiden, Alex Grassian and Tamar Melman for helpful comments on the manuscript. JWL was supported by a fellowship from the American Cancer Society.
Locasale JW, Cantley LC, Vander Heiden MG: Cancer's insatiable appetite.
Nat Biotechnol 2009, 27:916-917. PubMed Abstract | Publisher Full Text
Warburg O, Posener K, Negelein E: Ueber den stoffwechsel der tumoren.
Deberardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB: The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Cell Metab 2008, 7:11-20. PubMed Abstract | Publisher Full Text
Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB: Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
Proc Natl Acad Sci USA 2008, 105:18782-18787. PubMed Abstract | Publisher Full Text | PubMed Central Full Text
Hu W, Zhang C, Wu R, Sun Y, Levine A, Feng Z: Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function.
Proc Natl Acad Sci USA 2010, 107:7455-7460. PubMed Abstract | Publisher Full Text
Suzuki S, Tanaka T, Poyurovsky MV, Nagano H, Mayama T, Ohkubo S, Lokshin M, Hosokawa H, Nakayama T, Suzuki Y, Sugano S, Sato E, Nagao T, Yokote K, Tatsuno I, Prives C: Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species.
Proc Natl Acad Sci USA 2010, 107:7461-7466. PubMed Abstract | Publisher Full Text
Wishart DS, Tzur D, Knox C, Eisner R, Guo AC, Young N, Cheng D, Jewell K, Arndt D, Sawhney S, Fung C, Nikolai L, Lewis M, Coutouly MA, Forsythe I, Tang P, Shrivastava S, Jeroncic K, Stothard P, Amegbey G, Block D, Hau DD, Wagner J, Miniaci J, Clements M, Gebremedhin M, Guo N, Zhang Y, Duggan GE, Macinnis GD, et al.: HMDB: the human metabolome database.
Nucleic Acids Res 2007, 35:D521-D526. PubMed Abstract | Publisher Full Text | PubMed Central Full Text
Christofk HR, Vander Heiden MG, Wu N, Asara JM, Cantley LC: Pyruvate kinase M2 is a phosphotyrosine-binding protein.
Nature 2008, 452:181-186. PubMed Abstract | Publisher Full Text
Vazquez A, Liu J, Zhou Y, Oltvai ZN: Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited.
BMC Syst Biol 2010, 4:58. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text
Kilburn DG, Lilly MD, Webb FC: The energetics of mammalian cell growth.
J Cell Sci 1969, 4:645-654. PubMed Abstract | Publisher Full Text
Racker E: Why do tumor cells have a high aerobic glycolysis?
J Cell Physiol 1976, 89:697-700. PubMed Abstract | Publisher Full Text
Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, Gottlieb E, Vousden KH: TIGAR, a p53-inducible regulator of glycolysis and apoptosis.
Cell 2006, 126:107-120. PubMed Abstract | Publisher Full Text
Vander Heiden MG, Cantley LC, Thompson CB: Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Science 2009, 324:1029-1033. PubMed Abstract | Publisher Full Text | PubMed Central Full Text
Luo J, Solimini NL, Elledge SJ: Principles of cancer therapy: oncogene and non-oncogene addiction.
Cell 2009, 136:823-837. PubMed Abstract | Publisher Full Text


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Bruck V/A Track Matte Chrome - 160600mcgy
Bruck is internationally recognized as a leader in the development of innovative lighting systems with particular emphasis in the application of low voltage, halogen light sources and LED. The pioneer of a new approach to design, Bruck places three-dimensional technology at the forefront. Since the beginning, Bruck has been a developer and promoter of new standards in aesthetics, product quality and safety. Low voltage halogen light has evolved into one of the most highly demanded forms of lighting, finding extensive and varied applications in most styles of architecture. Much of the interior architecture of our living, working, and leisure spaces would be difficult to conceive without this brilliant, versatile, and stable light
Fixture Type: Track
Collection Name: V/A
Finish: Matte Chrome
Dimensions: H 78
The V/A Cord Suspension Clip comes with a plastic clamp connection to track, aircraft cable suspension standard 78" but can be field cut or factory lengthened. Supports recommended every 3'
Available in bronze, gold, chrome and matte chrome finishes
Overall Dimesions: 78" H
Manufacturer Name: Bruck Lighting Systems
Product Information
Collection Description: V/A is a pleasant, versatile track system with an extensive range of light fixtures. This low-voltage light system runs through the room cleanly and quietly. V/A is made with 2 connected round tubes of only 3/8" diameter each. The current carrying round tubes are isolated from each other and finished in bronze, gold, chrome, and matte chrome
Additional Dimension Information
Height: 78
Corporate Offices: (212) 226-4156 or 1-800-807-1826 158 Bowery, New York, NY 10012-4601
Copyright 2013 Lighting By Gregory, LLC All Rights Reserved.


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Oooohhh... my wet tight pussy needs a real dick like that!
That man not only has a big fat dick but he has a nice size set of balls on him
after hearing all the comments about his cock, I'm really happy mines that big lol
he was cumming for two minutes! Amazing.
Next video she does she'll be getting fucked with a baseball bat!!!
His orgasm was so epic it made me wet..mmmm
His BBC would look good inside of my big fat wetpussy
Looks like she handled it just fine. She took in the whole thing. Her stomach must be up in her chest
I would love to see this hot redhead suck my big black dick.


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Dark Blue is a 2002 film directed by Ron Shelton and starring Kurt Russell. The film is based on a story written for film by crime novelist James Ellroy and takes place during the days leading to and including the Rodney King trial verdict.
List of links to Dark Blue fansites:
Register to update information, save favorites, post photos, news stories and comments.


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http://www.liberiangeek.net – This quick tutorial will show you how to print from a shared printer installed on a (HowTos)
http://www.liberiangeek.net – This quick tutorial will show you how to print from a shared printer installed on a (HowTos)
http://www.linoob.com – So, finally the Ubuntu 10.04 "Lucid Lynx" LTS is released. Here are the Torrent files for you to download from: (General)
http://www.linuxinsider.com – For as long as human beings have walked the face of this Earth, more than a few have held dear the hope that their children would one day follow in their footsteps. Doctors encourage their kids to study medicine; lawyers advocate careers in law; rulers of evil empires create their own little clones. (General)
http://linuxfilesystem.com – User-submitted video from The Linux Foundation Video Site video.linuxfoundation.org Over one minute, but wanted to share the full video. (General)
http://www.linuxfordevices.com – Long-suffering smartphone maker Palm finally may have found a financial savior. Hewlett-Packard, the world's second-largest IT systems provider, announced in a teleconference that it has agreed to purchase the struggling smartphone maker for $1.2 billion in cash on hand, or about $5.70 per share.... (Embedded)
http://gamblis.com – I was using OpenSUSE Linux for a years. After that I try Ubuntu and until now, I stuck with Ubuntu. I will share my own experience and opinion about OpenSUSE 11.2 that currently I am testing. I was install OpenSUSE 11.2 in my Windows 7 host via VirtualBox 3.12. (Distributions)
http://www.downloadsquad.com – Filed under: Internet, Security, P2P (General)


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jGuru Forums
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Posted On:
Monday, November 11, 2002 08:09 AM
I wrote a MailSender class and jarred it as a library for use in other classes. Application using this mail library works fine in Jbuilder6 (with jdk1.3), however, when I try to run the jarred application in a jre1.4 environment, it throws following exception:
javax.activation.UnsupportedDataTypeException: no object DCH for MIME type text/plain; charset=us-ascii
Anyone has some insights? Thanks.


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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
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Before you head out for a day of adventures, get your wardrobe in shape with this geometric scarf! Scribbly, black lines draw a glamorous graph of warm-hued squares across this silky accessory - a dazzling design that's as eye-catching at an afternoon picnic as it is at along the bustling, downtown boulevards. Pair this patterned piece with a high-waisted pencil skirt, a breezy, wide-necked tee, and a pair of caramel sandals. Lay your eyes on this retro, geometric look, and you'll see your outfit from a whole new angle!
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Internet time guide scotched by astrology firm
A time-zone and daylight savings reference database used by systems including Mac OS X and Linux has been taken offline by a copyright suit brought by an astrology company
A time-zone and daylight savings reference database used by systems including Mac OS X and Linux has been taken offline by a copyright suit brought by an astrology company
Think $5 million is no big deal for Google? It isn't...it's what this judgement means that will cause some problems.
Microsoft has filed a major patent infringement lawsuit against Motorola -- and indirectly, Google, Linux and open source.The software giant's case against Motorola's Android devices won't slow the momentum of Google smartphones or its Linux-based open source operating system.
Oracle's ill-advised patent infringement case against Google will backfire, and hurt its prospects in the growing open source business market.That, according to Ubuntu creator and Linux giant Mark Shuttleworth, is the natural outcome of Oracle's case against the Linux-based Android operating system.
More great news for Linux distributors Red Hat and Novell, which prevailed in a patent infringement case brought by IP Innovation.IP Innovation, a unit of Acacia Research and holder of multiple patent portfolios, alleged that the two Linux companies infringed three patents that protect computer GUIs that span multiple work sites and that allow users to access icons remotely, the court documents show.
After the Microsoft-TomTom patent-infringement squabble -- settled by TomTom paying Microsoft an undisclosed sum -- I was wondering whether Microsoft might be more successful in unearthing new partners to sign Linux patent-protection deals. The answer seems to be yes.
Microsoft has filed a patent infringement case against a GPS-navigation system company. What makes the case interesting is its Linux connection.
The PC manufacturer says that Microsoft's patent-infringement claims have not affected sales of its Linux servers.
The Linux vendors have been sued for patent infringement by a 'portfolio licensing' company called IP Innovation
The PC manufacturer says that Microsoft's patent-infringement claims have not affected sales of its Linux servers
Now that the "first ever" suit for patent infringement has been lodged against two major Linux distributors, many Microsoft watchers are looking for the smoking gun that will somehow connect Microsoft to the case. So far, at least, that gun is nonexistent.
It appears as though the first patent suit against Linux -- targeting Red Hat and Novell -- is now official. According to Groklaw's Pamela Jones: IP Innovation LLC has just filed a patent infringement claim against Red Hat and Novell.
Looks like Microsoft's FUD campaign against Linux and open source is paying off, according to a new IDC study. Matthew Lawton, director of IDC's Worldwide Software Business Strategies Group, revealed some interesting tidbits from the non-public study in a conference call this week:The potential for copyright and patent infringement is the No.
Beyond giving Microsoft more fuel for its claim that Linux and open-source software violates 235 of Microsoft's patents (which these Linux customers need patent-infringement protection against in order to maintain peace of mind), Linspire's newly inked patent-deal with Microsoft also furthers a number of other Microsoft goals.
Both Fuji Xerox -- and now Samsung -- quietly have signed deals that "allow" them to sell their products without the threat of a Microsoft suit claiming patent infringement by Linux on Microsoft Windows and other products hanging over their heads.
Yes, litigating your way to software business success has its pitfalls, and it's ironies. Trouble for Microsoft is that it has the deepest pockets in town, and therefore an IP infringement magnet, whereas the Linux cup runnith over in all directions, with only a trickle available for a jury to potentially ransack. It just doesn't seem fair.
There have been a lot of words written about the comments made by Microsoft's CEO Steve Ballmer during a Q&A session after his keynote speech at the Professional Association for SQL Server (PASS) conference in Seattle last week (you know, where he said that Linux used intellectual property patented by Microsoft).
Following Microsoft's allegations over Linux patents, the software giant is now accused of intellectual property infringement by Alcatel
My blogging colleague (and ZDNet editorial director) David Berlind sent me an interesting follow-up note on my call for Microsoft to show proof that Linux is infringing on Windows patents -- as Microsoft CEO Steve Ballmer alleged last week.
Earlier this month we were all trying to figure out the reasoning behind the Microsoft/Novell deal. After all, the two companies have hardly been best buddies in the past.Microsoft's CEO Steve Ballmer, in a Q&A session after his keynote speech at the Professional Association for SQL Server (PASS) conference in Seattle, offers some insight.
Surface Pro 4 and Surface Book mean business, but no big threat to Apple
Windows 10
Surface Book: Microsoft's first laptop, coming October 26 starting at $1,499
Classic Steve Jobs disses you can put on your next resignation letter
Windows 10
With new Surface Book and Surface Pro 4, Microsoft aims high
For privacy and security, change these iOS 9 settings immediately


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Reevu Back Screen
Replacement rear lens for Reevu MSX1 and Reevu FSX1 Helmets. Helmets ship with Silver Mirror rear screens, Clear is also available.
Note: This is the Back Screen and not the faceshield. Back Screen is a replacement part and is somewhat challenging to install.
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text: More Star Wars Weekends Merchandise Revealed John Frost 03/02/2009 Disney Consumer Products, Star Wars, Walt Disney World Padawan Jedi Training is featured every day at Disney's Hollywood Studios, soon parents will be able to buy a pretty neat Disney exclusive Star Wars figure set to remember the moment with. This new toy will first be available at this years Star Wars Weekends. More details at EndorExpress.


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I think it is more relevant today though because manipulating photos has never been easier. And with a 24 hour news cycle demanding constant feeding, the temptation to "sex up" something is pretty great.
That said, in the end this is nothing new. The Soviets mastered this decades ago.
To me, the real issue is this -
Why do we automatically believe what we see?


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King George Foxes upend Cougars in softball donnybrook
- Details
- Last Updated on Friday, 04 April 2014 12:36
- Published on Thursday, 03 April 2014 07:00
- Hits: 2582
On Friday evening, under the lights of King George High School Softball Stadium, Monica Brandts brought the music to the dance. The senior Fox delivered a banner game against conference rival Courtland (1-1) that featured a 3-3 performance, including a two-run homerun, a run, and three RBIs--which led to a 7-2 win.
Led by freshman pitcher, Ashleigh Nalls, defensively, the Foxes (3-1) never froze under pressure. Nalls finished the game with 10 strikeouts, two walks, two hits, while giving up two runs. "Ashleigh certainly did her job, and she is only a freshman, but her strikeout count is very impressive, and will only get better," Foxes head coach Renee Parker said.
As for the Cougars, pitcher Vicki Varner gave up 10 hits, four walks, and two strikeouts.
After one and half scoreless innings, the Foxes capitalized on a scoring opportunity. After Brandts led off with a double, she later reached home on a series of two wild pitches.
The Foxes extended their lead in the bottom of the third inning. During a bases loaded situation, Alexis Sheehan scored on a wild pitch, and moments later, Taylor Hughes drove Shelby King home on a RBI single—giving the Foxes a 3-0 lead.
At the top of the fourth, the Cougars cut the Foxes' lead (3-2) to one, as Courtland catcher Torie Little knocked a two-run homerun over the left center field wall.
After picking up a run in the fourth on a Jaclynn Truxon RBI double, the Foxes offense blasted the Cougars for three additional runs in the bottom of the sixth inning. With one out, and two runners on base, Brandts blasted a towering homerun over the left field fence. The effort by Brandts extended the Foxes' lead to 7-2.
"We are striving to improve on our hitting so that our hits span the entire batting order instead of clustering, and leaving runners on base," Parker said. "I remember that it is early in the season, and we have been inside a good deal of the time. During the game, we just reiterated every inning that their offensive effort has to match their defensive effort, and that it's going to become increasingly difficult to win with three or four hits per game."
In the top of the seventh inning, the Cougars bravely made one last attempt at a comeback. With the bases loaded, and two outs, Nalls struck out Brook Belcastro for the final out.
On Wednesday, the Foxes will host a conference game featuring Eastern View. Also, on Friday, the Foxes will host their final game of the week against James Monroe. Game time is 6 p.m. Due to press deadlines, Tuesday's home game results against Caroline were not available.
Leonard Banks
Sports editor


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Originally posted by omarm1984
Wow 1.5million at 7pm.
I don't know if this has been mentioned already, but if you buy Ron Paul merchandise from his store it also counts as contribution.
Originally posted by GoodLifeGodLike
How did Cain win the Florida straw poll? Why the hell would you vote for someone that ran a pizza chain and worked for the FED? .
Originally posted by cassandranova
I think the reason you're not seeing such a huge day as happened in '07 is this whole campaign has been better run, better organized, and better funded from the beginning. I imagine the heavy donors have already laid down their max contributions.
One thing that would interest me greatly is someone had the figures for the number of unique donors for each candidate. Frankly, I think the "put your money where your mouth is" indicator would tell the truth of who has real popular support, and who has manufactured consent.
Originally posted by varikonniemi
I won't donate money since i live on the other side of the globe, but you mr. Paul have my full moral support!


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What is the difference between Proof, Brilliant Uncirculated and Bullion coins?
Designing Britain's decimal coins began in 1961, far earlier than you may imagine.
The Royal Mint is to issue its second limited edition £100 for £100 commemorative coin
The Royal Mint unveils new britannia proof collection
has been appointed to join the Accountability Board for the Irish Civil Service.
The Royal Mint has signed a Technical Cooperation Agreement with the Treasury Department of Thailand
For your convenience we have put together a list of some of the questions we are asked most frequently. If you are unable to find an answer to your enquiry, please contact us and we will be happy to assist.


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Current diagnostic labeling is causing confusion. One doctor may use the term Functional Neurological Disorder or Functional Movement Disorder, but another may use Conversion Disorder. This leaves many confused on their diagnosis and struggling to find where they fit. Individually these terms have different meanings, however, they are all labels for the same disorder.
What is Functional Neurological Disorder:
Functional Neurological Disorder is due to a problem with the functioning of the nervous system. Functional symptoms are thought to derive from the brain's inability to send and receive signals properly, as the result of physical and/or psychological precipitating factors.
Functional Neurological Disorder provides an umbrella term for a variety of symptoms of apparent neurological origin but which current models struggle to explain psychologically or organically. Presentation may be similar to a wide range of other neurological conditions. FND/CD can be as debilitating as Parkinson's disease and MS and have many similar symptoms. The most common misconception is that patients are in control of some or all of their symptoms. The patient does not consciously produce functional symptoms. A patient with conscious control of their symptoms has a different diagnosis such as Feigning, Malingering, or Munchausen Syndrome.
Very few effective treatment plans exist. Physical Therapy is the most effective form of treatment with a goal of re-introducing proper movement and motor control. The most common treatment plan is Cognitive Behavior Therapy (CBT), which yields a 13% 1 success rate. CBT is most effective for patients who have a psychological connection to their symptoms. Researchers, money, and volunteers are greatly needed.
Functional Neurological Disorder can present with any motor or sensory symptoms in the body including:
- Chronic Pain
- Non-Epileptic Seizures
- Speech Problems
- Involuntary Movements
- Paralysis/Weakness
- Headaches/Migraines
- Bladder/Bowel Changes
- Cognitive Changes
- Visual Changes
- Sensory Symptoms
- Sleep Disturbances
- Gait/Balance Changes
Given the occurrence of these medically unexplained symptoms in patients with organic brain injury, spinal injury, post-anesthesia and post-viral illnesses, the modern term moves away from psychodynamic theory and provides a useful label for what is a complex and little understood disorder.
Name Change: The additional parenthetical "functional neurological symptom disorder" has been introduced as it is more frequently used by neurologists who see the majority of these patients. Specialists who are current with research and understand the complexities of these symptoms are also moving away from the term Conversion Disorder. Conversion Disorder is more specific for those patients who can clearly define a psychological connection, which they are "converting" to their physical symptom. The majority of our Functional members do not relate to the "conversion theory".
GUIDED SELF-HELP FOR FUNCTIONAL (PSYCHOGENIC) SYMPTOMS, A randomized controlled efficacy trialM. SHARPE, MD, J. WALKER, MBCHB, C. WILLIAMS, MD, J. STONE, PHD, J. CAVANAGH, MD, G. MURRAY, PHD, I. BUTCHER, PHD, R. DUNCAN, MD, PHD, S. SMITH, PHD AND A. CARSON, MD, HTTP://WWW.NEUROLOGY.ORG/CONTENT/EARLY/2011/07/27/WNL.0B013E318228C0C7.ABSTRACT#


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Pookie Powell will enroll (but not play) at Memphis this year
Memphis coach Josh Pastner told CBSSports.com on Tuesday that Class of 2013 standout Pookie Powell will enroll in classes but not play this season for the Tigers.
Whether Powell will be allowed to practice remains undetermined.
"But the bottom line is that he's here," Pastner said.
Powell is a consensus top-100 prospect who committed to the Tigers last September. His availability has long been in question because of academics, and Pastner declined to get into specifics Tuesday. But a source told CBSSports.com that Powell will "basically be like Ben McLemore was at Kansas," meaning Powell will sit this season and then have four years of eligibility starting in 2014-15.
This development could be considered a positive for both Powell and Pastner.
Because Memphis will this season have three senior guards who averaged double-digits in points last season -- Joe Jackson, Chris Crawford, Geron Johnson -- and a fourth who did so two seasons ago, provided the NCAA grants a waiver to Missouri transfer Michael Dixon. Simply put, it's unlikely Powell would've been able to crack the rotation this season. So this development won't force Pastner to find minutes for the talented scorer in 2013-14, and it won't require Powell to lose a year of eligibility.
Pastner reiterated Tuesday that the school is still waiting to hear from the NCAA about Dixon's waiver but added that he remains optimistic. Also worth noting is that consensus top-100 recruit Markel Crawford has been cleared by doctors to compete without limitations after suffering a torn ACL last summer. Pastner told CBSSports.com on Tuesday that Crawford will not redshirt this season.
"He missed all of last season [in high school] and missing another season would just be too hard for him," Pastner said. "So Markel is going to play."


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Fight Brain Drain in Just 3 Minutes. ~ Catie Joyce
Brain drain.
You know what I'm talking about—that effect we get from spreading ourselves too thin, from being over-busy, over-productive and super stressed.
This leads to a lack of energy, depressed cognitive functioning and your joie de vivre flying out the window.
Here's something you can do to fight it. And the best part? You can do it in three minutes.
I found this little gem of a meditation while preparing to teach a Kundalini Yoga class on the sixth chakra. This is the chakra associated with the brain and the pituitary gland. The pituitary, often referred to as the "master gland," has its hand in most of our body systems, including metabolism, blood pressure, pain sensation, functioning of sex organs, adrenals and thyroid, to name a few.
This meditation stimulates the pituitary gland, balances the sixth chakra and replaces mental fatigue with a powerful renewed energy.
I have been practicing this before bed for the past few nights and sinking into an easy peaceful sleep immediately after. By releasing my mental stressors, I am able to create a space for new-found energy.
The more days in a row you do it, the more energized you will feel. Here's how to do it:
Meditation for Mental Fatigue
This meditation should be done only when you can relax afterwards. That's why doing it right before bed is perfect!
- Sit cross-legged or in a chair (or in bed) with a nice straight spine. Center yourself by chanting Ong Namo Guru Dev Namo three times. This mantra taps into the wisdom deep within us and all around us.
- Set a timer or your cell phone for three minutes.
- Interlace your fingers, right thumb over your left thumb and extend your two ring fingers so they touch. Your hands will be several inches from your chest, and ring fingers facing up and out at a 60-degree angle.
- Close your eyes and focus at your brow point, the space between your eyebrows, your third eye.
- Begin chanting a long Ong, by drawing out each sound in the syllable until you run out of air (Oooooooooonnnnnngggg). Inhale and repeat for 3 minutes. The sound will vibrate in your nasal cavity, giving it a nasal quality. This vibration stimulates the pituitary gland.The sound Ong is the vibration from which all creativity flows, or more simply, the Infinite. It is very similar to Om but is a more active form of the word. You can think of Om as the noun and Ong as the verb.
- When the timer goes off, inhale and hold the breath in for 10-20 seconds. Exhale and relax.
Sleep tight, sleep light, and feel that mental fatigue just melt away!
This meditation can be found in the book Meditation as Medicine, by Dharma Singh Khalsa, MD, and Cameron Stauth, a great resource on meditation.
Catie Joyce lives, plays and writes near the mountains of Western Maine. She is a certified teacher of Kundalini Yoga, as taught by Yogi Bhajan. Drawn to Kundalini Yoga for its holistic approach, she carries this over into her teaching through classes with a focus on calming the mind in order to uplift and elevate. Find her blogging about yoga, life and healthy eating. Connect with Catie on Facebook or Twitter.
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5 Responses to "Fight Brain Drain in Just 3 Minutes. ~ Catie Joyce"
I clicked on this because I really need it and it looks like an excellent idea. However, my brain is too drained to actually do it.
Has anyone else ever noticed that we're often too stiff to stretch, too out of shape to exercise, or too uptight to relax? Or am I just describing myself? Momentum is a funny thing; it appears to apply to our state of mind as much as our movements.
thanks for sharing this valuable article…. i will definitely try this daily.
glad you found it beneficial! would love to hear about your daily practice.
Ong also translates to "wholeness within oneself"
Thanks so much!


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Robert Cosgrave Tertiary21 2011/02/14
What Robert Cosgrave posts here may be a manifesto, but as he says at the conclusion of the post, "these changes are going to happen anyway. Global higher education systems will look like what I've described by about 2030." Now the model will not be exactly as he describes, but it will be close, I think. Here's what's in the manifesto:
- all higher education institutions need to be entirely autonomous, as non profit entities;
- a state supported student loan model, largely following the Browne Framework;
- to be eligible for loan funding, all of a modules material must be open access
- an open rating and reviewing system;
- an ideal of Deep Modularisation - the Bologna Process taken to it's logical extreme;
- by picking off the bottom rung prerequisites online first, you can access higher education without bothering with the Leaving Certificate;
- tripart governance: student loan and funding systems; labour markets and outcomes; quality management agency;
- tax incentives are strong for donations to long term institutional endowments.
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Using the app you will be able to choose the algorithm, paint over the area you want to delete and Snapheal will take care of the rest.
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