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Category Archives: Crime
One avenue for justice in Maryville, closed.
Across the internet, various groups are demanding justice for Daily Coleman, the 14-year-old girl who was allegedly raped by a popular high school football player from a well-connected family. But it's unclear what that "justice" would actually look like. A special prosecutor has been appointed to the case, and I'm hopeful she'll be able to shed light on all the facts. But were it not for conservative Supreme Court justices, Daisy could have had other options: She could have sued her alleged attacker under a federal cause of action established by the Violence Against Women Act. I'm writing about that in The Nation today:
Continue reading
Posted in Crime, Discrimination, Feminism, Gender, Law, Politics, Rape Culture, Sexual Assault Tagged Justice4Daisy, Maryville, The Nation, VAWA 9 Comments
Is Anonymous good for Maryville?
There's a part of me that thinks yes — when the legal system has failed, there are few other options to seek justice, and an internet collective isn't the worst one. But I'm also incredibly wary of unchecked power and the ethos of spreading information without verifying its authenticity or accuracy, and a movement that feeds on rage and indignation without any real accountability. It's particularly important to look at these issues when they're being carried out for a cause we believe in. Does the calculus change if Anonymous's tactics are leveled at someone we support? And then, are the tactics and ethics bad, or just the issue? I have a feeling this position will be very unpopular with the Feministe commentariat, but here goes: Continue reading
Posted in Crime, Law, Politics, Rape Culture, Sexual Assault Tagged Anonymous, Maryville 149 Comments
What's going on in Maryville?
In Maryville, Missouri, a 14-year-old girl was allegedly raped by a high school senior from a well-connected family. She and a 13-year-old friend snuck out to go to a party with some senior boys, mostly popular football players. They gave her alcohol until she blacked out, and one of them had sex with her. Photos were taken. Then they left her on her doorstep in the winter cold, where she nearly froze to death. Sexual assault, sexual exploitation and endangerment charges were all brought. Then they were dropped. The girl's family was essentially run out of town, and their house eventually burned down. The entire story is horrific, and the Kansas City Star offers a great piece of in-depth reporting here. Continue reading
Posted in Crime, Law, Rape Culture, Sexual Assault Tagged Maryville 30 Comments
Playing with Murder
An anti-abortion siege is under way in Albuquerque, and activists there are using tactics and rhetoric we've heard before — tactics and rhetoric that have a marked history of getting abortion providers killed. I'm detailing the pro-life strategy of violence in Salon: Continue reading
Posted in Crime, Feminism, Health, Politics, Religion, Reproductive Rights, Terrorism Tagged Abortion, Cheryl Sullenger, George Tiller, James Kopp, Operation Rescue, Pro-Life, Randall Terry, Salon, Scott Roeder 7 Comments
The Freedom to Abuse Kids
This week at the Guardian I'm writing about the gay conversion therapy ban passed in New Jersey, and how religious freedom is too often used as an argument for abusing kids — at the expense of children's own equal protection under the law.
Continue reading
Posted in Crime, Discrimination, Education, Health, Law, Medicine, Parenthood, Politics, Race & Ethnicity Tagged homophobia, religious fundamentalism 140 Comments
Treating Tracy Connelly like a woman
Last week, Tracy Connelly was murdered in the van where she lived with her partner. Police suspect the killer was a client; Connelly was a sex worker who lived across from St. Kilda Gatehouse. She was also a loving partner and beloved friend to other women in her community. Continue reading
Posted in Crime, Media & Media Literacy, Work Tagged Sex Work 19 Comments
Guilty verdicts in Richmond High School rape case
[Trigger warning]: In 2009, a 16-year-old girl was beaten and raped for more than two hours on the Richmond High School campus in California. She nearly died after the attack, which was perpetrated by multiple men while even more looked on. After four years, some justice is being done: Two of the accused have been found guilty and are facing long sentences. I'm obviously not a big fan of long prison sentences as a general rule, but for sadists who rape and torture a young woman for group entertainment over the course of several hours? Yeah, those guys probably shouldn't be walking the streets. Neither should the onlookers who encouraged the violence and did nothing to stop it. Continue reading
Posted in Crime, Rape Culture, Sexual Assault 68 Comments
Juror B37 has decided she's had enough publicity after all (with @MoreAndAgain update)
Just two days after acquitting George Zimmerman of second-degree murder and manslaughter charges for killing Trayvon Martin, Juror B37 — one of five white women on the six-woman jury — had signed with Martin Literary Management to write a book. President Sharlene Martin released a statement saying that B37 felt it important that the public understand her experience during the trial. After the public got to know B37 a little better, however, the book plans have disappeared. Continue reading
Posted in Crime, Law, Media & Media Literacy, Racism 45 Comments
Today in stupid crap
1. We're trashing a teenager who is doing her civic duty and whose friend was murdered. Good job, everyone, you should be proud. No, she doesn't speak like a 50-year-old white lawyer. But Rachel Jeantel is not on trial here, and the attacks on her are awful. Also, watching George Zimmerman's defense lawyer hammer the fact that Trayvon Martin told Jeantel that he was being followed by a "creepy-ass cracker" in a transparent attempt to stoke some racial animus among white people who are deeply offended at being called "crackers" was pretty appalling. Continue reading
Posted in Class, Crime, Feminism, Law, Politics, Racism, Reproductive Rights Tagged Abortion 138 Comments
America's Prisons are a National Disgrace
This week at the Guardian (and in the national news media) there's been much attention paid to the role of private contractors in our intelligence and military operations, after an NSA employee leaked classified documents about U.S. spying to Glenn Greenwald. I'm using my column this week to talk about a different kind of privatization in American security: The privatization of our prison system, which turns the building and management of prisons over to corporate entities. Of course, even non-privatized prisons in the U.S. are rife with abuses. But privatization creates strong financial incentives for increased incarceration; the actors who are incentivized are particularly powerful, politically connected and monied. There's also little oversight and regulation of private prisons, as attempts to do so are met with significant push-back. A part of the column (content warning: the text below and particularly the linked column include descriptions of violent prison abuses): Continue reading
Posted in Business, Crime, Law, Politics, Race & Ethnicity, Racism Tagged aclu, Comment is Free, Prisons, The Guardian 26 Comments
Texas jury says that sometimes, killing an escort is okay (Updated)
Ezekiel Gilbert contracted for services with Lenora Ivie Frago, an escort he found on Craigslist. At the end of their Christmas Eve engagement, he paid her her $150 fee, and she walked out — which angered him, because he'd assumed that sex was included as part of the package. Gilbert shot Frago in the neck, paralyzing her; she died of her injuries seven months later. His defense before the courts? That his actions were justifiable because she was stealing the $150 — and under Texas law, he was acquitted. Continue reading
Posted in Crime, Law, Sex 130 Comments
Not our fight: Male Violence and the Bystander Effect
[Trigger warning for domestic violence]
These good people, these people whom, albeit in different industries and capacities, are each individually working to make the future a better place than the present, do nothing. They, of relative privilege, watch the aforementioned horror unfold. Some are stunned. Some don't notice. Some shake their heads. It's a shame, they think. It's fucked up, they think. It makes my blood boil, they think. But they do nothing. They hold their girlfriends tighter. They back their friends away from the scene. They try to break their stares. They go get more drinks. These are good people. But they do nothing. They are silent.
A few try. Three university age young women try. They do as their friends tell them. Go get security, they say. But security does nothing. This is between a husband and a wife, they say. Please go back inside, they say. The young women beg their friends and the bar security to do something. They do nothing. Get away from the car, they say. There is nothing you can do, they say. You're going to get hurt, they say. You're being irrational, they say. It's not our fight, they say. Continue reading
Posted in Crime, Domestic Violence Tagged bystander effect, gendered violence, Guest Blogging, violence against women 92 Comments


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PHILADELPHIAInfectious diseases in Ghana tend to capture the most attention, but a quiet crisis may soon take over as the country's most threatening epidemic: cancer.
A new study published in January in the journal BMC Cancer, led by Kosj Yamoah, M.D., Ph.D., a resident in the Department of Radiation Oncology at Thomas Jefferson University and Hospital, takes aim at the issue by investigating prostate cancer diagnoses and treatment delivery in black men living in the West African region, in order to devise research strategies to help improve health outcomes.
Overall, many men are diagnosed at a later stage, with more than half opting out of treatment, they found. The researchers point to stigmas about cancer as a root of the problem.
"Cancer could eclipse infectious diseases as an epidemic if more awareness and intervention doesn't come about," said Dr. Yamoah, who grew up in Ghana until age 20, when he came to the United States. "Cancer can be very hush-hush because of cultural and financial issues and social stigmas associated with the disease. We need to bring awareness and address the needs of the population and barriers to care."
"Cancer is still perceived as a death sentence," he added. "People are scared to go to their doctor to find out if they have it, let alone to follow through with treatment."
In a retrospective analysis of 379 patients referred for treatment at the National Center for Radiotherapy and Nuclear Medicine at the Korle Bu Teaching Hospital (KBTH) from 2003 to 2009, the team found that 33 percent were diagnosed with metastatic disease and 70 percent had a prostate-specific antigen (PSA) score four times higher than men in the United States or Europe at time of diagnosis.
PSA screening rates in Ghana are low, the authors explain, and many men opt out of
|Contact: Steve Graff
Thomas Jefferson University

subset: commoncrawl


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Friday, June 13, 2003
© Copyright 2015 Clayton News Daily
Recently the Daily sports staff got into a discussion about some of the best baseball movies of all time, and yes, even some that aren't so good.Like the western, war movie, horror flick and romantic comedy Hollywood has put the subject of baseball into its very own genre. I don't call myself an expert on the subject of baseball movies, nor do I claim to be a film critic, but I have to admit some baseball flicks are very good, and some are a complete waste of time. For the record, here are some of my favorites and why I like them: Field of Dreams: The 1989 film staring Kevin Costner is by far one of the best baseball films ever made. This script is loaded with underlying themes. Of course, this film is pure fantasy, but my favorite scene is when Costner's character is reunited with his dead father. At the time of his death, the two men didn't get along. One of the most touching scenes shows the two men playing a game of catch. To me, this represents how generations of fathers and sons have shared a love of baseball, and what an important role the game has played in building a bond between father and son. The Sandlot: Maybe my favorite of all the baseball movies. The Sandlot is set in the 1960s in a far more innocent time. Although its a children's movie, I like it because it centers on kids playing the great American Pastime just for fun. I can relate to this movie, because growing up in the 1970s in a suburb of Philadelphia we had a vacant field in my neighborhood. The kids turned it into a sandlot. We played the game for hours without coaches and parents getting in the way. I had more fun playing in those games than in any organized sport, including when a soccer team I was on won a league title. Bull Durham: Another great baseball flick starring Costner. This film depicts life in the minors and deals with rookies, aging veterans and groupies. This movie is good for plenty of laughs and has a great cast, including Tim Robbins and Susan Sarandon. A League of their Own: Surprisingly a great baseball movie. The Penny Marshall film depicts life in the All-American Girls Baseball League formed during World War II. A good period piece deals with sibling rivalry, patriotism, how women can be good athletes and still be feminine. Eventually, they gain acceptance in a sport dominated by men. Marshall does a great job telling the story in flashbacks. Pride of the Yankees: Gary Cooper's depiction of Yankee great Lou Gehrig who died of ALS at 37 years of age. The disease was later named for the Yankee slugger. Although I have never seen this movie all the way through, I know a box of tissues is needed to watch this tearjerker. The Bad News Bears: Not a great baseball movie, but still a comical look at youth league baseball even though it's probably not suitable for young kids because of some of the language. In a way, it makes fun of how some parents take the game too seriously. Some things haven't changed in 20 years. Walter Matheau and Tatum O'Neal were very funny in this film. Of course there have been other baseball films not mentioned above, so I guess it goes to show as long as there is baseball, Hollywood won't run out of ideas for bringing the game to life on the silver screen. Doug Gorman is sports editor for the Daily. E-mail at email@example.com
More like this story
- Sports flicks that deserve recognition ( June 30, 2004 )
- Sloppy copies miss quality of film work - Zach Porter ( January 23, 2004 )
- Sloppy copies miss quality of film work - Zach Porter ( January 27, 2004 )
- Sloppy copies miss quality of film work - Zach Porter ( January 28, 2004 )
- Sloppy copies miss quality of film work - Zach Porter ( January 29, 2004 )


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I thought human beings didn't have exoskeletons.
Zelda from Pet Semetary
Damn she gave me nightmares.
Please tell me she's taking a break from a walk-on role on "The Walking Dead".
Bitch knows how to clear a room.
A passerby was confused when the creature started ranting about He-Man spoiling everything.
The zombie apocalypse is upon us. I call shotgun, literally.
Seriously, does she have AIDS?
I wonder if she clanks when she walks.
It's more like the sound of dead, dry leaves rustling…
Faaaaames. FAAAAAMES!
She looks so much better all covered up
Seriously, 'Skinny Girl?' More like emaciated drug hag.
Yes you can suck too much asshole.
Damnit Photo Boy, go easy with the Walking Dead screencaps right after the Winslet goodness!!
No, NO I would NOT
The promotional poster for the new season of AMC's The Walking Dead.
LeAnn Rimes think's she fat
Still trying to get into Castle Grayskull, I see.
Heavy Purse
Guess I wasn't aware that Mini Drive ditched the pounds, too!
That's a gristley sight.


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- Filed Under
Another rainy day! It has been rainy all week. We were able to get all the clothes dried on Monday even though there was a shower after the clothes were on the lines. We need to do laundry again and sure am hoping for a nice day on Friday or Saturday.
Tonight, the men from our church district will gather here to practice singing songs from the Ausbund, our German church songbook. It is a good way to get the younger men to learn how to lead all the songs. I need to make something today for a snack to serve to them after the singing.
We are enjoying asparagus, rhubarb, mushrooms and winter onions, all of those ...


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RE: MoveOn.dork
Jed, here's the box office numbers. After two weeks, An Incovenient Truth has taken in $3.9 million. I think even a certain Bennifer film did better than that.
Makes you wonder what record MoveOn.dork is talking about. Perhaps "highest gross for a documentary by a dull ex-Vice President who can't get over his loss in Florida and is prone to un-scientific alarmism"?


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The price difference between bulk and standard 36 exposure rolls isn't significant enough to justify the expense and labor of loading your own if you're not shooting a bunch; if you're shooting 10-20 or more rolls/week the cost savings does start to add up. The real benefit for those of us who shoot less seems to be the ability to load short rolls, say 12-18 exposures, when you have the need for short rolls. Plus I started at uni loading my own when I was studying darkroom, so it was a no-brainer (I'm good at those decisions) to do so again when I got back into it.
There are those who don't need to justify the expense. They like the hands-on aspect of film photography, and loading their own is a part of that. I suspect many of them graduated to LF. I have a certain amount of appreciation for this perspective.


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Debate swirls over control of California Air National Guard
WASHINGTON — California National Guard Adjutant General David S. Baldwin has a question for the Department of Defense: "Why are we trying to fix something that's not broken?"
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- EcuadorAgricultureFunding via Cooperativa San Jose
Dúo Marta D...GuatemalaClothingFunding via FAPE
Trust GroupGhanaRetailFunding via ASA Initiative FNGO
Ccori Chuspa Group
These group members balance their many domestic activities with retail in Urubamba city. A large portion of them make their living by selling clothes, food, supplies, handicrafts, etc. The male members have a moto-taxi, which they use for a transportation business. One of the women in this bank sells handicrafts (jewels, bracelets, painted ceramics, cloaks, etc.), other members have general stores where they sell rice, sugar, oil, etc. One member is a gardener and has a farm where he cares for animals (guinea pigs, chickens, ducks, etc.). One member has a restaurant, where she sells food (breakfast, lunch, and dinner). Another member has a tailoring studio.
The members are soliciting this loan for working capital so that they can offer more products and increase their sales, in order to better the quality of life of their families.
All the members appreciate and are thankful for the loan they are receiving through this system, and thus have themselves promised to make all their payments according to the agreed-upon schedule.
(The member Edison is not in the picture, with permission from the directors of the communal bank, because of reasons of health)
Nuestros socios alternan sus diversas actividades con el comercio minorista en la ciudad de Urubamba, una gran parte se dedica a la venta de ropas, comida, víveres, artesanía, etc. Los socios varones tienen moto-taxi que hace el servicio de transportes. Una de las socias de este banco se dedican a la venta artesanía (joyas, pulseras, huacos retratos, mantos, etc.), otras socias tienen tiendas de abarrotes donde venden arroz, azúcar, aceite, etc. Un socio es jardinero y tiene una granja donde cría animales (cuyes, gallinas, patos, pollos, etc.). Una socia tiene un restaurante donde vende comida (desayuno, almuerzo y cena). Otra socia tiene su taller de costura.
Los socios solicitan el préstamo para que lo utilicen como capital de trabajo y de esta manera incrementar sus productos y aumentar sus ventas, para dar mejor calidad de vida a sus familias.
Los socios valoran y agradecen el préstamo otorgado mediante este medio y así mismo se comprometen a cumplir con el pago de sus cuotas en el plazo establecido.
(El socio Edison no aparece en la fotografía porque pidió permiso a la junta directiva del banco comunal por motivos de salud).
Additional Information
Important InformationAbout Asociación Arariwa
Asociación Arariwa is a large non-governmental organization that started offering microcredit in 1994 to improve the quality of life, skills and equity of the population in the rural Cusco region of Peru. Arariwa serves the southern Andean provinces of Peru, and is distinguished by its efforts to reach the very poor, who often live in isolated rural areas. Arariwa fosters village banking, supports savings accounts, promotes access to education, and empowers women entrepreneurs (who make up 78% of its borrowers).
This is a Group Loan
In a group loan, each member of the group receives an individual loan but is part of a larger group of individuals. The group is there to provide support to the members and to provide a system of peer pressure, but groups may or may not be formally bound by a group guarantee. In cases where there is a group guarantee, members of the group are responsible for paying back the loans of their fellow group members in the case of delinquency or default.
Kiva's Field Partners typically feature one borrower from a group. The loan description, sector, and other attributes for a group loan profile are determined by the featured borrower's loan. The other members of the group are not required to use their loans for the same purpose.
About Peru
130View loans »
Success!! The loan was 100% repaid
- Repayment Term
- 8 months (Additional Information)
- Repayment Schedule
- Monthly
- Pre-Disbursed:
- Nov 11, 2009
- Listed
- Nov 19, 2009
- Currency Exchange Loss:
- Covered
- Ended:
- Jun 15, 2010


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Deep Geological Disposal of Radioactive Waste
Edited by
- W. Alexander, Wettingen, Switzerland
- Linda McKinley, Wettingen, Switzerland
This book presents a critical review of designing, siting, constructing and demonstrating the safety and environmental impact of deep repositories for radioactive wastes. It is structured to provide a broad perspective of this multi-faceted, multi-disciplinary topic: providing enough detail for a non-specialist to understand the fundamental principles involved and with extensive references to sources of more detailed information. Emphasis is very much on "deep" geological disposal – at least some tens of metres below land surface and, in many cases, many hundred of metres deep. Additionally, only radioactive wastes are considered directly – even though such wastes often contain also significant chemotoxic or otherwise hazardous components. Many of the principles involved are generally applicable to other repository options (e.g. near-surface or on-surface disposal) and, indeed, to other types of hazardous waste.View full description
Technical staff directly involved in radioactive waste management programmes; technical staff working on projects associated with such programmes; general audience seeking technical overviews of waste management programmes; waste producers; nuclear waste management companies
Book information
- Published: January 2007
- Imprint: ELSEVIER


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Our mission is to provide learning opportunities in formats designed to best meet the needs of our students and to best utilize available college resources. Through OTC Online, the College offers a wide variety of entirely online, hybrid, and web-enhanced courses designed for busy students who cannot regularly attend face-to-face classes or who simply prefer to learn in an online environment. If you would like to see if online learning is right for you, consider enrolling in our free Preparing to Learn Online course.
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Nice little storePosted on 02 / 14 / 2013
Small selection of organic produce, and a nice bulk section! You can even get molasses in bulk!
Cons: not in my town :)
Mon-Sat 9:30am-7:00pm, Sun 11:00am-6:00pmmore-less
Small selection of organic produce, and a nice bulk section! You can even get molasses in bulk!
This place is the real deal...every town in America should be so lucky to have a store like this. The staff is very involved in what they are selling and it shows. Very easy to shop and FULL of great merchandise! Outstanding produce...great prices.
Updated from previous review on Wednesday November 09, 2011
For a little health food store, Trillium has a great selection of produce and bulk items. Most of the staff is knowledgable. Prices are comparable to next closest health food store in Newport.
Trillium in the best place in Lincoln City to get fresh locally grown fruits & veggis. They also have an amazing selection on Vegan friendly foods as well!
This business supports the service that HappyCow provides :o)
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Last updated: 2012/01/31
Added: 2009/08/29
Added by: Guest


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How to add a blank clip.
1. Go to the Organize tab to choose Add Blank Clip in the drop-down menu of Add Files. You can also right click the blank area to select Add Blank Clip.
2. Go to Personalize tab, right click the blank thumbnail to choose Add Blank Clip.


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Personal Library Kit
Share must-read titles with friends knowing you'll get them returned on time. This old-school kit is filled with all of the tools needed (ink pad, stamp, checkout cards) to keep tabs on your precious paperbacks.
Original price: $15.
RS reader price: $12, knockknockstuff.com. Enter the code SIMPLE at checkout.
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Location: Located in Burj Nahar, Deira, Dubai, the hotel hugs the central activities that is uniquely Arabian. Step out and discover the grandeur that is Dubai and the beauty of Middle East hospitality defined exactly as it is at the Fortune Boutique Hotel.
Closest Metro Station: Deira City Centre Station.
Restaurants: One restaurant and one cafe.
Facilities: Outdoor roof-top pool, jacuzzi, sauna, steam room and fitness centre. Wi-Fi and business centre. Complimentary beach transfers.
Guest Rooms: 80 rooms.
Note: 24 hours check-in/check-out.
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Unique back office solutions can significantly enrich your current workflow in the areas of Claims Entry, Payment Posting, Accounts Receivable Follow Up, Denials Management and Credentialing. The hybrid workflow model ensures resourceful manpower, extensive healthcare expertise, and warrants the tedious work of aggressive follow ups, amongst other services, to be completed, all while away from your office. A virtual office genie can do all your work and increase your bottom line by up to 20%, all while reducing operational cost by as much as 30%. In order to survive the changes in the healthcare environment, medical groups can outsource various billing modules to third party solutions to maintain profitability. Off-shore labor power allows lowered operational costs and increases profitability instantly, putting medical groups in a lucrative space yet again. Don't let your frustrations slow you down, Eligibility Verification solutions are here to stay.
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In this paper a new technique of Z-Source Inverter (ZSI) based Solar Power Generation is developed and simulated using MATLAB-Simulink toolboxes. The Photovoltaic solar cells are better option for converting solar energy into electrical energy. Initial high cost and low efficiency PV cells have not yet been a fully attractive alternative for electricity users. For improving the performance, Z-Source inverter can be used in place of conventional Voltage Source Inverter (VSI) in Solar Power Generation System. The PV cell model is developed using basic circuit equations of the photovoltaic solar cells including the effects of solar irradiation and temperature changes. The Z-Source inverter is implemented to realize boosted DC to AC conversion. Results show that the energy conversion efficiency of ZSI is much better as compared to conventional voltage Source Inverter (VSI). The developed system is tested for linear and nonlinear load. The Harmonic Analysis has been done to know the quality of the power generation.
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Aneuploidy in neuroblastoma tumors is not associated with inactivating point mutations in the STAG2 gene
1 Department of Clinical Genetics, Institute of Biomedicine, University of Gothenburg, Sahlgrenska University Hospital, SE-413 45 Gothenburg, Sweden
2 Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden
BMC Medical Genetics 2013, 14:102 doi:10.1186/1471-2350-14-102Published: 2 October 2013
Chromosomal instability is a hallmark of human cancer caused by errors in mitotic control and chromosome segregation. STAG2 encodes a subunit of the cohesion complex that participates in mitotic chromatid separation and was recently found to show low expression and inactivating mutations in Ewing's sarcoma, melanoma and glioblastoma.
In the childhood tumor neuroblastoma (NB) segmental chromosomal alterations are associated with poor prognosis whereas tumors displaying whole chromosome gains and losses have a much better prognosis.
As the genetic contribution to aneuploidy is unknown in NB, we investigated the presence of STAG2 mutations through sequence analysis of all 33 coding exons in 37 primary NB tumors.
Results and conclusion
As no STAG2 mutation was detected in this study, we conclude that inactivating mutation of STAG2 is not likely causative to neuroblastoma aneuploidy.


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Chickpeas can be found in most Middle Eastern kitchens, lending their versatile starchiness to falafel, hummus, and crisp, flavorful aprons. Sample the triple threat of the legume family with this Groupon.
The menu includes baba ghanouj ($5.95–$6.95), beef shawarma with hummus ($9.95–$10.95), lamb kebabs ($13.95–$15.95), and shrimp scampi served with vegetarian moussaka ($15.95–$17.95).
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pentahotel Warrington4
Aston Avenue Birchwood Business Park, Warrington, WA3 6ZN
Price FromView Rooms
- Very Good
- 49 guest reviews
"Nice modern hotel, good room - shower could have been better, but adequate. Team friendly and overal I'd give this hotel a thumbs up...."
"If you are expecting a decent hotel with courteous staff, you'll be very disappointed. If you are looking to share your night with CHAVs and..."
"Room was nice, staff were friendly, overall it was a great place to stay. Would have preferred a more varied menu that included more vegetar..."
"The room was nice and clean......but a light did not work in the bathroom making it rather dark. (I reported this to reception on leaving an..."
"Amazing stay, , gorgeous hotel, very clean, excellent service from staff! Late check out on Sunday for free! Has to be one of the best plac..."
About the hotel
BE HAPPY IN WARRINGTON! Don't worry! For the location could hardly be better: The pentahotel Warrington is the perfect place to stay for trips to Manchester (only 20 minutes away) or Liverpool (only 25 minutes away). But Warrington itself has also plenty to offer, too. In particular a pentahotel, that cannot fail to delight you.
For relaxed, stylish and modern lifestyle that you will simply like. STYLE WITHOUT STIFFNESS Wasn't the conventional reception desk a real horror story with its stiff atmosphere and all the tedious waiting around? Everything is completely different in the pentahotel Warrington. The pentalounge – in the heart-warming design of star Italian architect, Mattheo Thun – invites you to a most relaxing welcome! The restaurant, bar, relaxation area and meeting-point all do the same! All pleasantly different. • 103 rooms with a 100% relaxation factor • pentalounge: come in and start to relax straightaway. • 2 meeting rooms for up to 41 delegates • Check-in: from 3pm, check-out: until 12. 00pm • Public transport: bus stop directly in front of the hotel • Safety deposit box available • Free WiFI • every Sunday breakfast until 10. 30 and late check-out free of charge until 15. 00 upon request • Writing table, telephone, 32" flat screen TV, hair dryer • Pay TV and sports channels free of charge in each room
Read MoreLess
Room Availability
Showing Tuesday 13 October 2015 to Wednesday 14 October 2015Change Search
Facilities Show/hide
- Main
- Hotel Non-Smoking Throughout , Disabled Facilities , Smoking allowed in bedrooms
- In room facilities
- Air conditioning in rooms , Tea/Coffee making facilities in each room , Hairdryer in each room , Iron And Board In Each Room , Telephone In Each Room
- Hotel services
- 24 Hour Reception , Limited Hours Room Service , Limited room service for hot food , Laundry/Valet Service , Wake Up Call Available
- Family friendly
- Cots available , Interconnecting rooms available
- Parking
- Car parking available onsite
- Business
- Wi-Fi Available , Meeting Facilities , In-room Broadband , Wi-Fi Available In Public Areas , Wi-Fi Available In Rooms
- Dining
- Restaurant , Lounge Menu , Bar
- Leisure
- Gymnasium , Fitness Centre
- In room entertainment
- TV , Satellite TV , Games Console , [Channels] News , [Channels] Sky Sports , [Channels] Movies (Free) , [Channels] Movies (Pay Per View) , [Channels] Foreign (European) , [Channels] Foreign (Other) , [Channels] Music , [Channels] Childrens , Radio
- Other
- Doctor on call , Ground floor bedrooms , Lift to all floors , Public Air Conditioning
- Accessibility
- Disabled Access Public Areas , Disabled Access Bedrooms , Disabled toilets on ground floor , Wheelchair Access , Wheelchair Access To Reception , Wheelchair Access To Restaurant , Wheelchair Access To Bar , Wheelchair Access To Conference Rooms , Wheelchair Access To Disabled Car Parking Spaces
Useful Info Show/hide
- From 15:00 hours
- Until 12:00 hours
- 28/10/2014 to 27/10/2022 - £3.00 per night for residents £9.00 per day for a day pass (non-residents). Valid until midnight, if you are travelling to us by car please use the postcode WA3 6GA for SatNav The price shown is based on the occupancy and dates you have searched for. Prices and availability are subject to change based on the arrival date, number of nights and occupancy searched for. All prices are inclusive of all local taxes.
- Pets are not allowed
Customer Reviews
Our reviews are from genuine LateRooms.com customers. We verify that the customer has stayed before leaving a review.
Very Good
73% would recommend it to a friend
Customer service
Food quality
Room quality
Thumbs up
Nice modern hotel, good room - shower could have been better, but adequate.
Team friendly and overal I'd give this hotel a thumbs up.
Read More Less
Don't even bother
If you are expecting a decent hotel with courteous staff, you'll be very disappointed.
If you are looking to share your night with CHAVs and NEETs who'll keep you awake until 3:30am at the expense of £79, then you'll find at home here. On a positive note, the hotel is clean with plent of parking.
Read More Less


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Who Pays Income Taxes?
How Complex is the Tax Code and What are the Compliance Costs for Taxpayers?
Is the Income Tax Truly Voluntary?
How Have the Top and Bottom Income Tax Brackets Changed Over Time?
Do Members of Congress Pay Income Taxes?
Do Members of Congress Pay Social Security Taxes?


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Pope Benedict XVI Arrives In St. Peter's Square
Pope Benedict XVI waves to the faithful as he arrives in St. Peter's Square for his final general audience on Wednesday in Vatican City. The Pontiff attended his last weekly public audience before stepping down Thursday. Pope Benedict XVI has been the leader of the Catholic Church for eight years and is the first Pope to retire since 1415. He cites ailing health as his reason for retirement and will spend the rest of his life in solitude away from public engagements. Franco Origlia/Getty Images


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Los Zocos Club
- Closest aiport: 20km to Lanzarote Airport
- 100m to Beach
In the heart of Costa Teguise, Los Zocos Resort is the ideal destination for those who want a vibrant and unforgettable experience in the Canary Islands. Spend your days lying on ... Continue reading
In the heart of Costa Teguise, Los Zocos Resort is the ideal destination for those who want a vibrant and unforgettable experience in the Canary Islands. Spend your days lying on the fabulous Cucharas Beach, located just 100m from the resort, or feel the bustling town life first hand, with its various pubs and discos to help you melt nights into mornings.
Boasting a range of apartments set against a gorgeous backdrop of lush gardens, Los Zocos offers all the facilities to guarantee a relaxing and exciting stay in Costa Teguise. Recently renovated with stylish décor, the resort offers two swimming pool areas with an entertainment and a chill-out area with a small bar. If travelling as a family, the resort offers a kid's pool and a shallow pool for infants.
For a memorable culinary experience, be sure to try El Boulevard, the newly refurbished restaurant offering a Mediterranean corner, international grill and a stunning international and Asia-Pacific buffet, all under the same roof. Enjoy a vibrant atmosphere for your nights at the live music bar or head to the AquaMarina Disco for delicious cocktails and music to keep you dancing until the early hours.
More active holidaymakers can enjoy a lively game of tennis or rent bicycles, whereas the kids will be thrilled to explore the playground and compete in a crazy game of mini golf. The large number of restaurants around Los Zocos, ranging from British-style pubs to traditional Spanish tapas bars, will make for a memorable and delicious culinary experience.
Whether you are planning your next holiday for a special occasion or simply looking for a last minute getaway, let loveholidays.com help you find the perfect hotel. From the Sands Beach Resort to the Santa Rosa Apartments and everything inbetween! Book your holiday online today and save!
- Two swimming pool areas
- Bicycle rental
- Billiards
- Darts
- Entertainment staff
- Evening entertainment
- Games room
- Golf course (within 3 km)
- Hiking
- Mini golf
- Table tennis
- Tennis court
- Kids' club
- Children's playground
- Children's pool
- Shallow infant's pool
Other facilities
- 24-hour front desk
- ATM/cash machine on site
- Babysitting/child services
- Car hire
- Currency exchange
- Laundry
- Tour desk
- Vending machine (drinks)
- Vending machine (snacks)
- Two buffet restaurants
- Four bars
- Designated smoking area
- Facilities for disabled guests
- Family rooms
- Mini-market on site
- Non-smoking rooms
- Safety deposit box
- Shops (on site)
All Inclusive
- Breakfast, buffet, daily: 07:30-10:30
- Lunch, buffet, daily: 12:00-14:30
- Dinner, buffet (El Boulevard Show restaurant or El Mirador restaurant); Reservations Required (in high season limited seating), daily: 18:30-21:30
- Snacks, daily: 11:00-17:00
- Locally produced alcohol; locally produced non-alcoholic drinks, soft drinks; hot drinks; cold drinks, daily: 10:30-20:00
- Locally produced alcohol; locally produced non-alcoholic drinks, soft drinks; cold drinks (La Jaima Pool Bar); unlimited (from AI drinks list), daily: 20:00-23:00
Room facilities
The Los Zocos Club Resort features one and two bedroom apartments that can accommodate from 3 to 5 people respectively. All units have recently been upgraded with a new modern contemporary design as well as upgrading the bathroom and kitchen. Each apartment has a private bathroom (shower or bath, hair dryer), separate bedroom(s) with ceiling fan, living room with sofa bed, fully equipped kitchenette (oven or microwave, kettle, toaster), and a private terrace with outdoor furniture. Furthermore a minor additional charge guests can request a safe box, Satellite TV, and Wi-Fi Internet access. Rooms are cleaned and towels changed 5 times a week. Bed linen is changed twice a week.
Other Information
Just 39 km from the hotel is Timanfaya National Park, home to the famous Montanas del Fuego, and renowned for its unique 'Martian' landscape dotted with rare species of plant.
Price Overview
The prices shown below show the cheapest holiday offers for the Los Zocos Club in Costa Teguise. Please use the price links to see all holiday deals available for that month.
|Price Overview
|Holidays from
|Avg. Daily Temp (°C)
|Avg. Evening Temp (°C)
To make booking a holiday at Los Zocos Club in Costa Teguise easier for you, we provide a range of different payment options. To find out if you can book Los Zocos Club with a low deposit holiday option, please click the "Price and Availability" button above.
The smallest and most recently developed of the island's three main holiday resorts, Costa Teguise is situated on the southeast corner of Lanzarote and is a haven for families and sun-seekers. Although it is a purpose built resort, Costa Teguise manages to have a nice community feel to it, with lots of little squares around which the bars and restaurants are located. The resort is more low key than some but still has plenty to do with a wide variety of shops and restaurants for all tastes and of course lovely beaches for holiday-makers to relax on. Playa de las Cucharas is probably the best of the three beaches with uninterrupted views and crystal clear blue waters, but Playa Bastian is another idyllic spot to enjoy the sub-tropical sunshine.
Resort Rating
There is plenty of entertainment for holiday makers in and around Costa Teguise for all ages. Watersports, including sailing, windsurfing, jet skiing, snorkelling and scuba diving can be arranged from the beaches, while just outside the resort is an 18-hole golf course and a water park for the kids. Further afield visitors can explore the Timanfaya National Park and the ancient capital, Arrecife. Boat trips and submarine tours go from Puerto Calero, ten miles (16km) west of Costa Teguise, and camel and horse rides can be organised. Most activities can be organised through the tour operator reps, though it is sometimes cheaper to book directly.
There is a good range of restaurants in Costa Teguise catering for all tastes and pockets. For dining out, try Coffee and Cream Bistro Bar, Vesubio Restaurant, Restaurant Montmatre or El Bocadito, which specialises in traditional Spanish tapas. Besides a number of local establishments, there are plenty of Italian, Indian, Thai, Chinese and seafood restaurants. For those longing for home, there are several fish and chip shops that offer traditional cod and freshly made chips, and other places that serve up English breakfasts and screen Premier League football on big screen TVs.
The nightlife in Costa Teguise is not legendary - party animals generally take a taxi to Puerto del Carmen, a larger holiday resort ten miles (16km) to the west. Costa Teguise's Mo vita Disco Bar is its best-known party venue and there are nice bars around the marketplace to start the evening off. Try the Fiddler's Bar and the Sunburnt Arms or Hennessy's Irish Bar if you're craving a refreshing pint of Guinness. For something different try Legends Bar which provides entertainment such as a hypnotist or an Abba tribute band. There is also a casino in the Hotel Oasis.
Costa Teguise has a variety of shops around the resort and in the La Cucharas Shopping Complex, selling all the usual tourist tat for holiday makers, as well as a few electrical duty-free stores. The busy Sunday market at Teguise is well worth a visit, selling a variety of locally produced goods from pottery to tablecloths along with the inevitable 'I've been to Lanzarote' t-shirts.
It is possible to get good bargains in the electrical duty-free stores when on holiday in Costa Teguise, but remember that you can't take purchases back to the shop once you have left the island. Check everything works and that all batteries, cables and plugs are included; that you receive a European guarantee, not an Asian one; and that all electrical items have a CE stamp. Whilst water is safe for cleaning teeth and washing food, it is very high in mineral content and can cause bad stomach problems. Bottled water should be used for drinking.
Essential Information
Time Zone
Plug TypeVoltage 220V 50Hz
€1 = £0.74
This week's weather forecast
Photos of the Costa Teguise area
Panoramio is a photo-sharing network designed for users to upload their own travel photos and place them on the map, giving you a better idea of what to expect from a location before you visit. We decided to use Panoramio because we want you to see images that reflect real life, not just the glossy photos that the brochures provide.
Photos provided by . Photos are under the copyright of their owners.
Hotel address : Avenida Islas Canarias, 15, Costa Teguise, Lanzarote, Canary Islands
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Questions and Answers about Los Zocos Club
If you can't find what you're looking for or if you have a question about this specific hotel, please get in touch via the Add a Question button below. Our knowledgeable team will aim to respond to your question within 72 hours. In the meantime, previously asked questions can be found below and answers to some of the most commonly asked questions can be found on our FAQs page.
can some-one tell me is there 1 or 2 los zocos hotels in costa tequise as im getting 2 differant map readings. many thanks. 1 Answer
There is only 1 los zocos resort in costa teguise Lanzarote
The address we have is
Hotel address : Av. Islas Canarias, 15, Costa Teguise, Lanzarote, Canary Islands
Added 2 months, 1 week ago.
By Zara.Drant, loveholidays.com team member
Which appartments (1 bed) have the sun and what view do they have. Which appartments ( 1 bed) have the shade and what view do they have. On the third floor. Look forward to hearing from you. Pauline. 1 Answer
Hi Polly, Unfortunately we do not know the answer to your question. If you contact the hotel via firstname.lastname@example.com they will be able to advise you.
Added 8 months ago.
By Leanne, loveholidays.com team member


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So sorry, but only 4 items are allowed for comparison. I blame the gnomes and so should you.
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Hey, this is the old version. Check out the new The North Face Terra 65 Pack.
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Return to Main Street: The Bowery
Last Spring our Main Street NYC series traveled along the Bowery checking in on the health of local businesses and institutions. We visited the Bowery Mission, a decades-old pizza supply shop, and a new eco-friendly home goods store, the Green Depot. We ended our trip at 250 Bowery, a huge hole where a luxury hotel was supposed to go up. Back in March, site manager Joesef Ayoub said that the problem with the project was financing. Its building permits expired in April and the site remains empty. But that's not the only hotel development changing life along this main street.
You can listen to a conversation with reporter Brigid Bergin and WNYC's Richard Hake about this story here:
Roberta Degnore (above) is standing across the street from 187 Bowery, the apartment building she agreed to leave after her landlord sold it over a year ago. Degnore lived on the second floor above a restaurant furniture store for close to 30 years. As a writer and filmmaker the massive 1,500 square foot loft was Degnore's living and working space. She received a financial settlement in exchange for moving, but Degnore says all she really wanted was help finding a comparable space in the neighborhood.
Brack Capital Real Estate purchased 187 Bowery Street, the building where Degnore lived, for over $7.5 million in the summer of 2008. This building, along with those on either side of it, was expected to be demolished. The company lists vague details on its website about a 'boutique hotel' project slated for the site. For now, scaffolding is the only sign of activity at the site. No one from Brack returned repeated calls requesting an update on the project's status.
In December 2008, the Cooper Square Hotel did open. The 21-story hotel is located at on the corner of East 5th Street and the Bowery.
Some local residents who opposed the building's construction formed a grassroots preservation organization, the Bowery Alliance of Neighbors, or BAN. The group drafted a plan to rezone the east side of the Bowery, which would include height caps and provisions to protect buildings of special significance. The Bowery was not included in last year's rezoning of the East Village and Lower East Side.
Officials at City Planning says they are aware of the community's concerns and are willing to meet with residents on proposed solutions. No date for that meeting had been set at the time of this report.
Battered blue plywood surrounds a 30-foot hole at 250 Bowery. Construction at the site has been suspended for over a year. It was slated to become a luxury, green hotel. Currently, several court cases related to the project are pending against the developer Peter Moore Associates. For now, garbage collects around the edges of the site.
Further south at 91 Bowery, a new luxury hotel is going up on the corner of Bowery and Hester Street. The construction there destabilized the neighboring buildings and ultimately led to the demolition of 128 Hester Street.
Chris Kui (center) is the head of Asian Americans for Equality. He was joined by Susan Stetzer (left) the district manager for Community District 3, who held a protest with several long-term residents outside 128 Hester in late October. The building was demolished two weeks later.


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Included fan helps drive reliability, USB and eSATA support, quiet operation.
Little bit ugly, little bit boxy, unnecessary screw adds installation time to the slide-top design.
Addressing different designs for external storage enclosures is a lot like taking a microscope to Pop Tarts and counting the sprinkles to determine which pastry variety contains maximum tastiness. Or at least, that's what it feels like. Because there's not anything functionally different with Antec's Veris enclosure than any of the many, many other enclosures we've tested. You slap a drive in, connect a USB or eSATA cord, and call it a day.
Well, sort of. While the crux of the device is simple and problem-free, the Veris still makes for a little bit of a different experience. For starters, the drive enclosure comes with a single screw that must be removed before you can shove a drive into the box. It's a minor annoyance, given that other enclosures we've seen—we're looking at you, Icy Dock —are one-hundred-percent screw-free. But unlike the Icy Dock enclosure, the Veris comes with a silent fan on the bottom of the device that churns a constant, albeit low amount of air over your hard drive.
Speed-wise, the Veris does nothing to hinder or boost the performance of your drives in any capacity. The USB and eSATA connections are as easy to access as the device's power switch. Given its relative silence when placed near a churning computer, the downward-facing light on the front of the Veris is a little poor at telling you whether the enclosure is on or not. We would have much preferred a simple, outward-facing LED.
The minutia of our criticism should suggest exactly how we feel about this device. While it's a little boxy and ugly, it's still a solid addition to both your desk and desktop PC. The Veris is not the best device for those who plan on switching through a ton of drives, but it's a great mate for a single drive. The enclosed gentle, breezy fan ensures drive reliability, while the device's near-silent operation ensures user sanity. It's a win all around!


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"Due to the rare nature of infantile spasms, physicians have not had ready access to unbiased educational materials for parents and caregivers of infants with IS," said Lawrence Brown, M.D., Associate Professor of Neurology and Pediatrics at Children's Hospital of Philadelphia. "This is an important step that we are taking this week to shed light on a condition that needs to be better understood by the child neurology community, pediatricians and caregivers."
Funding for Infantile Spasms Awareness Week and the educational materials created by CNF was provided by Questcor Pharmaceuticals via an unrestricted educational grant. Questcor did not have any involvement regarding the content of the information in the brochure, DVD or the website.
About Infantile Spasms
Infantile spasms (a.k.a. West Syndrome) is a severe, ultra-rare form of epilepsy that typically begins in infancy. It is estimated that there are fewer than 2,000 new cases of IS in the United States each year, giving IS orphan disease designation. Infantile spasms typically occur in the first year of life, often beginning between three to six months of age. Infantile spasms is characterized by head drops with associated outstretched arms. (These spasms have also been described as nodding, salaam seizures, and jackknife seizures.) Often, in the beginning, the attacks are brief, infrequent and not typical, so it is quite common for the diagnosis to be delayed. Frequently, due to the pattern of the attacks and the cry that a child gives during or after an attack, the attacks are initially thought to be due to colic or gastric distress.
About the Child Neurology Foundation
Founded in October 2000, the Child Neurology Foundation was created as the outreach and philanthropic arm of the Child Neurology Society. Members of the CNS include more than 1,300 child neurologists from the United States, Canada, as wel
|SOURCE Child Neurology Foundation
Copyright©2009 PR Newswire.
All rights reserved


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FBI Needs Hackers Who Aren't Stoners. Good Luck On That
Cyber crime is rampant, A lot of hackers smoke pot. Law enforcement can't fight without hiring law breakers.
Cyber crime is rampant, A lot of hackers smoke pot. Law enforcement can't fight without hiring law breakers.
A motorist near Casper was recently pulled over for a routine traffic violation. The Wyoming Highway Patrol found more than they bargained for inside the vehicle...
The operators are looking for marijuana, but they are not with law enforcement
If you are for the legalization of marijuana in Wyoming, why? If you are against, why not?
Planes were towing their banners at yesterday's home opener for the Colorado Rockies. y friend Bob saw ads for McDonald's, Gieco and.... Marijuana.
With regards to our changing times and the legalization of marijuana becoming more popular across America, are we ready for this? Here is the first advertising to be accepted by a TV station.
Here comes the 1st legally sanctioned marijuana club in the country. Club Ned opens in a few weeks, in Nederland, Colorado. The owners of the club say they have jumped through all the legal hoops so members can smoke the chronic in peace. Club Ned is located just up the canyon from Boulder, at 154 Highway 72.
Ever since Colorado legalized marijuana, the authorities have been trying to get a grip on how to handle drivers that are high. It's come down to: Treat stoned drivers just like drunk drivers. If you or anyone you know has ever had to deal with a DUI, you know it creates major and expensive hassles in your life, and it should.
The Wyoming House of Representatives has voted against a bill that would have decriminalized possession of small amounts of marijuana.
The Wyoming chapter of NORML, The National Organization for the Reform of Marijuana Laws, marches on our state capitol on this first day of the return of The Legislature...
The Public Policy Editor for The Denver Post posted this position for a recreational marijuana editor on Twitter. With weed going legal in Colorado on January 1, 2014, The Post is looking for a reporter to cover the new frontier...
According to Yahoo news, some pot smokers are taking advantage of the new "e-cigarettes" that vaporize liquid nicotine, for tobacco smokers, and using that same process for marijuana, who's smokers must use cannabis in wax or liquid form...


text: Dolores Anderson | IBDB: The official source for Broadway Information IBDB: The official source for Broadway Information Official Broadway League sites: - sites - broadway.org broadwayleague.com broadwayfanclub.com kidsnightonbroadway.com stagespecs.org tonyawards.com Quick Search For: In This Category: All Show People/Org. Theatre Season Dolores Anderson Performer Female Productions ProductionsDate of ProductionsVery Warm for May[Musical, Comedy, Original] Performer: Dolores Anderson [Dolores]Nov 17, 1939 - Jan 06, 1940The Boys from Syracuse[Musical, Comedy, Original] Performer: Dolores Anderson [Assistant Courtezan, Singer]Nov 23, 1938 - Jun 10, 1939 Find out where Dolores Anderson and are credited together © 2001-2015, The Broadway League, All Rights Reserved. (Copyright and Disclaimer)


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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
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After slipping into a lace dress and adding a gold statement necklace, you step into these genuine-leather flats. Etched with slim lines in a geometric pattern on the pointed toes and counter, these coral d'Orsay slip-ons are a fine foundation for your most-loved looks. Watch your wardrobe go from basic to brilliant with these sweet flats!
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ARLINGTON, Va., Nov. 6 /PRNewswire-USNewswire/ -- In recognition of Diabetes Awareness Month, The HealthCentral Network's (http://www.HealthCentral.com) MyDiabetesCentral.com has launched a special feature, which highlights the voices of those with diabetes and provides important information to further the understanding of this condition. The special section, which can be found at http://www.healthcentral.com/diabetes/diabetes-awareness-month.html, promotes the unique perspectives and experiences of the individuals who comprise HealthCentral.com's diabetes community.
MyDiabetesCentral.com is also inviting four guest bloggers to inform the community about the importance of the awareness month. The four bloggers come from all walks of diabetes life: Kerri Morrone is a blogger with type 1 diabetes, Teri Robert is a blogger and patient advocate with type 2 diabetes, Karen Lavine is a Certified Diabetes Educator, and Shannon Lewis is a caregiver who blogs about the challenges of raising a child with type 1 diabetes.
By sharing personal stories and advice, HealthCentral.com's diabetes community utilizes MyDiabetesCentral.com as an open forum for candid conversations about diabetes management and awareness. Beyond a place to connect and share experiences, MyDiabetesCentral.com is a resource for information on diagnosis, treatment and new research - a place where those who have diabetes can educate others to create a better understanding of the disease.
"Greater global awareness of diabetes and greater availability of
treatment for all people is clearly needed," Dr. William Quick,
endocrinologist and MyDiabetesCentral.com expert, said. "It is our
responsibility as diabetes healthcare professionals, and as patients and
family members, to share the message: Diabetes is something you can live
|SOURCE The HealthCentral Network
Copyright©2007 PR Newswire.
All rights reserved


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Use ARCs to Create a Buzz Before You Launch Your Book
Advance Reader Copies (ARCs) are a routine part of a traditional publisher's process for launching a book. The should be something you use in getting your self-published book off to a good start as well. The idea of an ARC is to get a copy of your book into the hands of opinion makers – reviewers, media contacts, influencers – prior to the launch of your book. These readers can help create a buzz about your book as it is becoming available.


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"We all love the bright lime green color on the girls. " (E3176)
" These are the best youth shoulder pads out there for the money!!" (E21589)
"The bag was wonderful, a good size and lots of room for all my daughters stuff. We loved it. " (E1849)
Epic Sports
Baw Men's SS White Body Eagle Cool-Tek Polo Shirts [E33991]


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Watch These Dads Tossing Kids Around in the Pool — Daily Distraction
Hurling your child several feet through the air—legally—and sending him crashing into the water is a high point in life for any dad.
Hurling your child several feet through the air—legally—and sending him crashing into the water is a high point in life for any dad.
You may have noticed a pumpkin or two around the neighborhood lately. Okay, maybe more than two. They're everywhere. This means you've probably fallen victim to at least a little bit of the hype and purchased some Halloween pumpkins. But what do you do with them in just a few days, when Halloween is in the rearview mirror?
Halloween is here, finally! But just because you've got a sweet zombie outfit on doesn't mean that some clever homeowner might not turn the tables and give YOU a major fright.
How can you resist a Chihuahua in a Superman cape?
Oh, to be a kitten and be able to just go to sleep anywhere, anytime.
Do you have a monkey? If so, keep a close eye on him.
Dogs seem to understand very well that human babies are there to be licked.
A butterfly must be fascinating to a dog.
The World Series starts tonight, so let's take a moment to appreciate the most important people at the game: the fans.
Okay, we're just going to come right out and say it: this burglar doesn't stand a ghost of a chance.
He didn't get his ball and chain, but he did wind up in jail.
Yesterday we showed you how cats had gotten the upper hand in the ages-old clash between felines and canines. Today, the shoe is on the other, um, paw?


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Really Simple Syndication (RSS) is a convenient way to follow websites of importance to you from one convenient place. Like the front page of a newspaper, you see the headlines for all of the new content that's available. An example of content that you can access by using an RSS feed is the Focus on Small Business column that is part of the Support for Small Business website.
The benefit of RSS is that you no longer have to go to different websites to obtain the latest information on your topics of interest. An RSS feed updates your reader with summaries of the content, and then you decide which articles you want to read by clicking a link. How many websites have you intended to go back to and then forgotten about them?
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Jamie King, the director of Michael Jackson ONE, talks about the creation of the show, how it differs from Michael Jackson THE IMMORTAL World Tour, and the lessons Michael Jackson taught him.
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Wednesday, June 6, 2012
© Copyright 2015 Gwinnett Daily Post
Imogene Yancey Hannah, age 85 of Loganville, GA passed away June 5, 2012. She is survived by her loving husband of 62 years, Cecil Hannah; twin sister, Kathleen Yancey Rice; brother, Charles and Nettie Yancey all of Loganville; 7 nieces and nephews, 13 great nieces and nephews, 33 great great nieces and nephews. Mrs. Hannah was a life long native of Gwinnett County and a longtime member of Snellville United Methodist Church. She retired from AETNA after 30 years of service. A Funeral Celebrating the Life of Imogene Yancey Hannah will be held Thursday, June 7 at 11:00AM at Tom M. Wages Snellville Chapel with Rev. Tommy Jordan officiating. Interment will be held at Chestnut Grove Baptist Church Cemetery. The family will receive friends Wednesday from 4pm until 8pm, at the funeral home. Condolences may be sent or viewed at www.wagesfuneralhome.com. Tom M. Wages Funeral Service, LLC, A Family Company, Snellville Chapel 770-979-3200, has been entrusted with the funeral arrangements.
More like this story
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- Patsy Timms ( November 7, 2011 )
- Carmon Rice ( February 18, 2009 )


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Dickerson Wants To Be Texans' No. 2 Receiver
As heard on J&R July 21, 2011 5:50 PM
Dorin Dickerson, the Texans' WR, discusses his goals for next season and how he's stayed in the shape in the off-season.
Dorin Dickerson
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SACRAMENTO -- Assembly Republicans want to review the work of court-appointed receivers who have been given control over parts of California's prison system.
In a Jan. 23 letter obtained by the Orange County Register, Assembly Republican Leader Mike Villines wrote Assembly Speaker Fabian Nunez, D-Los Angeles requesting that Nunez form a committee to monitor the receivers.
Assemblyman Todd Spitzer, R-Orange, said Republicans are most concerned about Robert Sillen, the receiver in charge of prison health care who has threatened to seize more than $1 billion in state funds.
"We have to be given the opportunity to question what he's doing," said Spitzer, who acknowledged oversight would be possible only if the independent receivers agreed to participate.
Nunez's office said the speaker has been out of the country and hasn't had time to consider the Republicans' proposal.
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Pentagon spends in Africa to stem Islamist terrorism
WASHINGTON — The Pentagon has begun a burst of spending in Africa, expanding its main base on the continent and investing in air facilities, flight services, telecommunications and electrical upgrades as the U.S. military deepens its involvement in a region with a rising threat of Islamist terrorism.
Hundreds of millions of dollars in expenditures, detailed in unclassified federal documents, demonstrate Africa's increasing importance to U.S. military and counterterrorism operations as the war in Iraq ends and American troops withdraw from Afghanistan.
By far the most significant expansion is occurring at Camp Lemonnier in the deeply impoverished nation of Djibouti, a backwater on the coast of the Gulf of Aden, just north of Somalia. The sprawling base, built out of a onetime outpost of the French Foreign Legion, has been the Pentagon's primary facility in Africa for a decade.
Defense officials last month awarded $200 million in contracts to revamp the base's power plants and build a multistory operations center, aircraft hangar, living quarters, gym and other facilities on a sun-scorched 20-acre site next to the tiny country's only international airport (with which it shares a runway).
The projects are part of $1.2 billion in planned improvements over the next 25 years that will speed Camp Lemonnier's transformation from a makeshift installation where a few hundred Marines once slept in tents into an enduring 600-acre base that now houses about 4,000 U.S. military personnel and civilian contractors.
"Africa is front and center now for the Pentagon, so that means Lemonnier is front and center," said Rudolph Atallah, former counterterrorism director for Africa at the Defense Department and now chief executive of White Mountain Research, a security consulting company.
U.S. officials have been grappling with the threat posed by al-Qaida-linked militants in Somalia, Yemen and North Africa.
The Pentagon pays $38 million annually to lease the base from Djibouti.
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Page 1
Direct transition metal-catalyzed functionalization of
heteroaromatic compounds
Ilya V. Seregin and Vladimir Gevorgyan*
Department of Chemistry, University of Illinois at Chicago, 845 West Taylor St., Chicago, Illinois
During the last two decades there has been considerable growth in the development of catalytic
reactions capable of activating unreactive C–H bonds. These methods allow for the synthesis of
complex molecules from easily available and cheaper precursors in a fewer number of steps.
Naturally, the development of C–H activation methods for direct functionalization of heterocyclic
molecules, invaluable building blocks for pharmaceutical and synthetic chemistry and material
science, has received substantial attention as well.
The traditional methods for functionalization of heterocyclic compounds usually employ
different types of cross-coupling reactions, where the heterocyclic partner bears either a
metal-containing functionality (nucleophilic component) or a halogen atom (electrophilic
component) (A and B, Scheme 1). Friedel–Crafts-type alkylation (C) is also well-
established, however it is limited to electron-rich substrates only and often is not
regioselective. Alternatively, direct functionalization of heterocycles via the activation of
unreactive C–H bonds (D) constitutes a much more attractive approach.1
Pd-catalyzed arylation of heteroaromatics with aryl halides is the most developed type of C–
H functionalization of heterocyclic compounds. The earliest report containing an example of
a very low yielding intramolecular arylation of pyridine appeared in 1984.2 Since then, this
chemistry has been rapidly growing and new types of direct intra- and intermolecular
reactions, as well as cascade transformations of heterocycles, such as C–H arylation,
heteroarylation, vinylation, and formal alkylation, have been developed. Palladium
complexes are among the most frequently used catalysts; however, there are some reports on
efficient rhodium-catalyzed transformations.
This review provides mechanistic discussions on transition metal-catalyzed direct C–H
functionalization of electron-rich and electron-deficient heterocycles, discusses different sets
of conditions used for functionalization of both types of heterocycles, and covers the most
essential synthetic applications.
1. C–H arylation of electron-rich heterocyclic systems
1.1. Reactions involving Pd0/PdII manifold: mechanistic studies—One of the
most abundant protocols for transition metal-catalyzed functionalization of heteroaromatic
compounds involves a Pd0/PdII catalytic cycle. For C–H arylation of heterocyclic substrates,
© The Royal Society of Chemistry 2007.
*email@example.com; Fax: +1 312 355 0836; Tel: +1 312 355 3579 .
NIH Public Access
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Chem Soc Rev. 2007 July ; 36(7): 1173–1193. doi:10.1039/b606984n.
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four distinct mechanisms have been proposed to date: electrophilic aromatic substitution
(A),3 C–H activation (B),4 cross-coupling (C),3 and Heck-type arylation (D)5 (Scheme 2).
The first systematic mechanistic studies on the palladium-catalyzed arylation of heterocycles
were reported by Gevorgyan.6 Indolizine, one of the most electron-rich heterocycles
known,7 was chosen for these studies. Experimental and theoretical studies were performed
to evaluate possible involvement of any of the four mechanisms depicted in Scheme 3.
First, to evaluate the possible involvement of a Heck-type process D, a cascade Heck
reaction8 of 1 (Scheme 3) was tested, aiming at spirocyclic compound 3. The latter would
form via the second carbopalladation of the first Heck reaction product 2. However, trials on
this cascade transformation with allyl ether 1 were unsuccessful, producing a mixture of C-3
arylated indolizines 4 and 5 instead. In another set of experiments, indolizine 6 was
subjected to reductive Heck reaction conditions,9 aiming at dihydroindolizine derivative 7
(Scheme 4). However, numerous efforts to perform this transformation under a variety of
reduction conditions failed. It was rationalized that if this reaction does operate via a Heck-
type mechanism,5 the arylation of 6-carboethoxyindolizine 8 should lead to 7-arylindolizine
10 (Scheme 5). However, 8 was selectively arylated at C-3 instead, producing 9 as a sole
Next, the possibility of C–H activation pathway (B), proposed by Miura for the
"coordination-assisted" C-3 arylation of 2-carbamoyl-substituted thiophenes,10 was tested.
Normally reactions proceeding via C–H activation motif experience a substantial isotope
effect.11 However, studies performed by the Gevorgyan group on indolizine 11 (Scheme 6)
indicated no isotope effect (kH/D = 1.0), thus disfavoring involvement of C–H activation
(Path B, Scheme 3) in this transformation.6
Furthermore, the absence of KIE at position C-3 of indolizine 11 contradicts another
possible mechanism: a cross-coupling type process (Path C, Scheme 2), as it is known that
reactions proceeding via proton–metal exchange should also exhibit a substantial KIE.12 The
possibility of involvement of this mechanism was originally proposed by Miura for the
copper-assisted C-2 arylation of azoles, where arylation of "acidic" sites of the heterocycles
was promoted by the addition of Cu salts.3 However, addition of copper salts during the
arylation of indolizine 6 resulted in greatly prolonged reaction times and reduced yields,
thus, not supporting Path C.6
Next, experimental and theoretical studies were performed to elucidate the possible
involvement of the electrophilic aromatic substitution process (A). This mechanism has
often been considered as the most probable mechanism for arylation of heterocycles.3,5,13,14
Naturally, the absence of an isotope effect in the arylation of 11 (Scheme 6) does not
contradict pathway A, as the deprotonation event in the electrophilic mechanisms is not a
rate-limiting step.15 Additionally, it is well known that the pyrrole ring of an indolizine is
electron-rich and easily undergoes electrophilic substitution reactions.7 DFT calculations
perfectly confirmed this point, revealing that the pyrrole ring has an extended HOMO
density, whereas the LUMO mostly resides at the pyridine ring.6 To gather further support
for electrophilic mechanism A, kinetic studies were performed (Table 1).6 As expected for
an electrophilic path, the EWG-substituted indolizine underwent the slowest arylation
among tested substrates (Method I, Table 1). A similar trend of reactivity was observed in
the Lewis acid-mediated Friedel–Crafts acylation of the same indolizines (Method II, Table
1), thus strongly supporting electrophilic nature of the arylation (Path A, Scheme 2).6
Shortly thereafter, Sames reported detailed mechanistic studies on C-2 and C-3 arylation of
indoles.16 Three mechanisms that rationalize strong preference for the palladium-catalyzed
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C-2 arylation of indole were considered (Scheme 7): Heck-type reaction (A), non-
electrophilic metalation of the C-2 position (B), and the electrophilic metalation at C-3 with
or without subsequent migration to C-2 (C or D, respectively). While pathways A and B
were briefly commented on, electrophilic mechanisms C and D received the most attention
in this work.
First, it was mentioned that a Heck-type mechanism (Path A) might be operational in this
process.5,17,18 In this case, the process would involve a carbopalladation step, followed by
anti-dehydropalladation or by isomerization and syn-elimination.19 However, the
isomerization step requires a reversible α-hydride elimination to form a carbene
intermediate, a process unknown for palladium (unlike for Pt or Ru).20
The next possible pathway is a non-electrophilic C-2- palladation of indole (Path B), which
has been proposed by Tollari21 and Nonoyama.22 However, it was concluded that
involvement of this scenario for non-functionalized indoles is unlikely, as the presence of a
strong directing group is a strict requirement.21,22
Sames further evaluated the feasibility of pathways C and D, which involve an electrophilic
palladation of indole.16 It is well known that electrophilic substitution at indole has a strong
preference for the C-3 position.23 On the other hand, multiple examples of palladium-
catalyzed arylation demonstrate predominant or exclusive C-2 selectivity. Thus, an
interesting suggestion was made: the initial metalation does occur at the more nucleophilic
C-3 carbon, followed by the C-3 to C-2 migration of an aryl palladium moiety, resulting in
the apparent C-2 arylation (Path C). Better stabilization of the C-2–Pd bond by the adjacent
nitrogen was proposed to be the driving force for this migration.24 Kinetic isotope effect
studies performed by Sames revealed an unexpectedly large kinetic isotope effect of 1.6 at
C-3, a position in 15 where no substitution occurs (Scheme 8), which was rationalized in
terms of secondary KIE. However, it was pointed out, an unusual value of 1.6 may be the
sum of several rate-contributing steps. At the same time, the KIE at C-2 was ~1.2, evidently
too small for the cleavage of C-2–H bond at the rate-limiting step. Sames concluded, that
these results, if not clearly in support migratory pathway C, seem to be somewhat
contradictory with the mechanism wherein a direct palladation at position C-2 takes place.
In conclusion, the mechanisic pathway for Pd0/PdII-catalyzed arylation of electron-rich
heterocycles, proposed by Miura3 (Path A, Scheme 2), has received the most unambiguous
experimental support so far. The key step of the process involves an electrophilic attack of
arylpalladium species at the heterocycle. The regioselectivity of this step is governed by the
distribution of electron density in the substrate. In indoles, however, the altering
regiochemical outcome may be a result of palladium migration (Path C, Scheme 7).
Nevertheless, the potential involvement of other aforementioned pathways or mixed
mechanisms can not, at this point, be completely ruled out.
1.2. Reactions involving Pd0/PdII manifold: synthetic applications
Miura investigated reactions of bromo- and iodobenzene with imidazoles, oxazoles, and
thiazoles 16 (Scheme 9).3 It was found that in the presence of catalytic amounts of
Pd(OAc)2 and PPh3 in DMF, the coupling products, 5-arylated azoles 17, can be synthesized
selectively in good yields.3 Interestingly, it was shown that the addition of stoichiometric
Cu(I) salt significantly increases reactivity of the C-2 position of azoles leading to 2-arylated
products 18. Although the trend of reactivity in the electrophilic reactions of the azole ring is
known to be C-5>C-4>C-2, in the presence of CuI alone (no Pd catalysis), a substantial
amount of C-2 substituted product formed, which was attributed to an alternative operating
mechanism. It was proposed that exchange of the most acidic proton at C-2 with Cu results
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in an organocopper intermediate, which is enabled to undergo cross-coupling with aryl
halide to form C-2 arylated product 18 (Scheme 9).3
Furthermore, Miura reported a method for palladium-catalyzed multiple arylation of
thiophenes 19 and 22 (Scheme 10).25 Thiophene carboxamides were shown to undergo
triarylation, accompanied by formal decarbamoylation in the presence of Pd(OAc)2,
Buchwald's ligand (P(o-biphenyl)(tBu)2) or P(tBu)3, and Cs2CO3 in refluxing xylene.25 3-
Substituted thiophenes 19, bearing EWGs, can also be converted to triarylated products 21
in high yields. At the same time, selective diarylation can also be achieved in the presence of
an excess of ArBr (Scheme 10).
Later, Miura disclosed a similar protocol for palladium-catalyzed C-2 and C-5 arylation of
thiazoles 25, 26 and benzothiazoles 27 with aryl bromides (Scheme 11).26 The best yields of
diarylated products were obtained by employment of bulky phosphine ligands (P(o-
biphenyl)(tBu)2) or P(tBu)3 in DMF at 150 °C. At the same time, arylation of thiazole 31
bearing a carboxanilide function as sacrificial group in less polar o-xylene afforded 4,5-
diarylated thiazole 32 exclusively, (Scheme 12).26
One of the first direct heteroarylations of heterocycles was reported in 1989 by Ohta who
investigated palladium-catalyzed coupling of 2-chloro-3,6-dialkylpyrazines with protected
indoles 33 (Scheme 13).27,28 Reactions of 1-tosylindole with chloropyrazine in the presence
of catalytic Pd(PPh3)4 led predominately to 3-heteroaryl indoles 34 in moderate to good
yields. Alternatively, under the same conditions, 1-alkyl- and benzylindoles were shown to
undergo substitution at C-2, affording the corresponding 2-heteroarylated products 35 in
good yields (Scheme 13).27,28
Later, Ohta demonstrated palladium-catalyzed heteroarylation of other electron-rich
heterocycles 36 (Scheme 14).28 Coupling of chloropyrazines with pyrroles, furans,
thiophenes, and a number of azoles in the presence of Pd(PPh3)4 gave the corresponding
pyrazine-substituted products 37 in moderate to very good yields.28
Furthermore, this methodology was extended by Ohta for the arylation of furan, thiophene,
and their benzo-analogues 38 (Scheme 15).29 The developed protocol allowed for the
synthesis of a variety of compounds arylated selectively at the C-2 position (39). It was
noted that electron-deficient aryl components generally result in lower yields, while aryl
bromides bearing EWGs react very smoothly.29
In 1990, Grigg reported an intramolecular arylation of iodo-1-aroylpyrroles and indoles 40
(Scheme 16).30,31 It was demonstrated that in the presence of Pd(OAc)2, PhPh3 and
tetraethylammonium chloride the reaction affords good yields of tri- and tetracyclic products
Later, Kozikowski disclosed a methodology towards polycyclic indoles 43 featuring
intramolecular cyclization of bromoaryl-bearing indoles 42 (Scheme 17).32 It was
demonstrated that intramolecular C–H arylation proceeded readily in the presence of
Pd(PPh3)4 and KOAc in DMA, affording polycyclic products 43 in very good yields.
Suzuki reported synthesis of imidazo[4,5-c]quinolin-4(5H)-one ring systems 45 via an
intramolecular palladium-catalyzed cyclization of 44 (Scheme 18).33 The effect of solvent
and type of base used in the C–H arylation of imidazole ring were thoroughly investigated.33
In 1995, Merour reported a protocol for the intramolecular annulation of 46, leading to
polycyclic indole- and pyrrolo[2,3-b]pyridine-containing structures 47 (Scheme 19).34 The
employment of Pd(PPh3)4–KOAc catalytic system allowed for obtaining annulated products
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47 in moderate to very high yields. Notably, it was demonstrated that this method perfectly
tolerates sensitive functional groups, such as aldehyde and halogen (Scheme 19).34
In 1997, Lemaire reported a method for the arylation of thiophenes 48 under Jeffery's
conditions35 (Scheme 20).36,37 It was found that in thiophenes bearing an EWG at C-2,
arylation occurred at C-5 regiospecifically. In the case of 3-substituted substrates 48, the
reaction was not regiospecific, leading to the formation of C-2–C-5 disubstituted products.
The arylation of 2-carboxaldehyde thiophene proceeded in rather moderate yields; however,
the reaction of 2-cyanothiophene gave arylated products in excellent yields (Scheme
Later, Lemaire disclosed an approach towards 2-aryl- and 2-heteroaryl-benzothiophenes 51
(Scheme 21).38 It utilized a phosphine-free system: Pd(OAc)2, K2CO3, and crown ether. In
particular, good results were obtained in the presence of dicyclohexyl-18-crown-6. In the
case of sensitive functional groups, such as aldehyde, a quaternary ammonium salt was used
as an additive instead of a crown ether. Importantly, this protocol allowed for obtaining high
yields of arylated products 51 from benzothiazoles 50 bearing both electron-donating and
electron-withdrawing groups (Scheme 21).38
A method for regiodivergent palladium-catalyzed monoarylation of azoles 52 with aryl
iodides, immobilized on a solid polymer support, was developed by Kondo (Scheme 22).39
The switch of regioselectivity (C-2 vs C-5) was primarily achieved by the employment of
CuI, which led to the exclusive formation of C-2-functionalized product 54, while only C-5
arylation occurred in the absence of copper additive. Remarkably, unsymmetrical diarylation
was demonstrated in the sequential derivatization mode (Scheme 22).39
McClure reported a regioselective method for the C-5 arylation of furaldehyde 55 (Scheme
23).40 In the presence of PdCl2, PCy3, Bu4NBr, and KOAc, a variety of 5-arylfurfurals 56
were obtained in high yields. The mechanistic rationale proposed included both Heck-type
carbopalladation and electrophilic metalation pathways. However, no experimental support
for these mechanisms was provided (Scheme 23).40
Sharp developed a method for the regioselective Heck-type arylation of 3-ester-substituted
furans and thiophenes (Schemes 24 and 25).5 Notably, it was suggested that a change in the
reaction mechanism can occur depending on the reaction conditions (Scheme 24).
Particularly, a nonpolar solvent and phosphine ligands used in Method A stabilize the σ-
bonded Pd(II) species, favoring the Heck-type carbopalladation and affording intermediate i
(see above, Scheme 2), which leads to the C-2-arylated product 58. Alternatively, in Method
B, a polar solvent and an absence of stabilizing phosphine ligands are likely to promote the
ionization of the Pd–X to form an electrophilic Pd(II) species. These species would be
expected to react preferentially at the more electron-rich C-5 position of the heterocycle,
resulting in the regioisomer 59. Application of these methods (A, B, C) for arylation of
furans and thiophenes 60 led to selectively functionalized heterocycles 61 in moderate to
good yields (Scheme 25).5
Mori reported a mild and regioselective C-2 arylation of thiazole 25 employing a palladium/
copper(I) catalytic system in the presence of tetrabutylammonium fluoride (Scheme 26).41 A
variety of 2,5-diarylthiazoles 63 bearing two different aryl groups were synthesized in a
subsequent second-fold arylation of 62 under standard Cu-free conditions (Scheme 26).41
Later, Mori investigated Pd-catalyzed arylation reactions of thiophenes 64 possessing Br-
substituent at C-2 with aryl iodides, while preserving the carbon–bromine bond (Scheme
27).42 The arylation with ArI was shown to proceed selectively at C-5 in the presence of
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