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OXFORD, England, May 9, 2013 /PRNewswire/ --
-- UshStat® video selected to showcase theme of "Life-changing Research" --
Oxford BioMedica plc ("Oxford BioMedica" or "the Company") (LSE: OXB), the leading gene-based biopharmaceutical company, today announces an update from the 2013 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) held in Seattle, Washington (USA) on 5-9 May 2013. The ARVO annual meeting is the largest gathering of eye and vision researchers in the world and this year's theme is "Life-changing Research".
Oxford BioMedica's collaborators at Oregon Health & Science University's Casey Eye Institute, Portland, Oregon submitted a video to ARVO which featured a patient who has been treated with UshStat®. UshStat® is a novel gene-based treatment for Usher syndrome type 1B, the most common form of deaf-blindness, and was designed and developed by Oxford BioMedica using the Company's proprietary LentiVector® platform technology.
The video was awarded second place in a contest to promote the ARVO 2013 theme and was showcased at the Sunday 5 May, 2013 Keynote Session: click here to watch the video.
Oxford BioMedica also presented two posters entitled "Glaucoma-GT, a novel gene therapy treatment for primary open-angle glaucoma" (abstract ID: 2741 - A0185) and "The LentiVector® Gene Therapy Platform for Ocular Disease: a clinical update" (abstract ID: 2744 - A0188).
John Dawson , Chief Executive Officer of Oxford BioMedica, said: "Our ocular gene therapy programmes continue to receive recognition from the ARVO community and we thank our collaborators at OH
|SOURCE Oxford BioMedica plc
Copyright©2012 PR Newswire.
All rights reserved


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Since I know who the buyer is,lol..u didnt get too much did ya now Constructo....ur last tech info gave ya a 27-30 base...dont mean cra$$...it goes when they decide,not your amateur analysis...Hows VIK and WIF,go try analyzing them again,lol
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text: So for the past few days I have been getting terrible sharp pains on my left side. If anyone has ever had an ovarian cyst, thats exactaly what it feel like. I used to have a cyst on my right ovary, and when they went to remove it it had overtaken my entire ovary, so I had to have my right ovary removed along with my FT. So anyway this feel just like a cyst but on my left side. My only concern is that this is an etopic pg since obviously the egg came from that side, and the pain is where essentially my FT would be. It comes and goes, but when it hits, its really painfull! I called and talked to a nurse at my OB Clinic, and she said that her recommendation would to go to the ER, but the fact that its not a constant pain and there is no bleeding is good, and if I can wait it out until my appointment on Dec 9th, to try. Only because my insurance hasnt kicked in yet. Its possible they MAY cover an ER visit, but I dont really know. Im waiting for the financial advisor to call me back. I just dont know what to do. Any suggestions? I dont have the pain right now.... Im 5 weeks 2 days today. So I dont even know IF I went in that they would even be able to tell.... Help!!


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List Price: US$2.16
|Free shippingTo UNITED STATES
Total Price:US$1.99
All packages from DX.com are sent without DX logo or any information indicating DX.com. Due to package variations from suppliers, the product packaging customers receive may be different from the images displayed.
To enable volume discounts on this site, use coupon code: BULKRATE during checkout. You will see a discount applied at the bottom of the shopping cart. Competitive pricing is available. Contact us for details.
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Ultra-Mini USB napájecí adaptér / nabíječka - EU Plug (100 ~ 240V AC)
It suffers by overheating. I recommend always to keep unplugged this charger from electricity after ending of charge devices. I have damaged plastic case of this charger by own overheating yet.
doesn't do the job at all. during 20 minutes of charging the battery gained only one percent. a waste of money
phone charges! once burned once included. very poorly made. not useful.
Pros: Cheap Very small Does the job Cons: None so far I would recommend this product if you're looking for a cheap charger
Compact and cheap, anything you can hope from an adapter. When i connected an android to it, it started to smell like something was when... Read more
Ultra-Mini USB Power Adapter/Charger First time use it 5 minute boom!!! Short Curcuit my country use 220 V
Very inexpensive and so useful. Delivers 5.5 V while in open circuit. Over 11 Ohm load delivers just 380 mA instead of 500 mA as Anyway I... Read more
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Viva Voce
A Portland, OR based duo & married couple, Viva Voce have an extremely diverse sound. The music captures both the sweet and the melancholy, with comparisons ranging from the fey pop antics of Belle & Sebastian to the transcendental cinematics of the best Grandaddy. Their sound seems far more expansive than that of a simple duo, and are currently seeking soundtrack & commercial work through their agents at Bank Robber Music.
No stations playing Viva Voce now
No albums found
The Centre of The Universe


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Unique onsite security service for vacant properties
Outstanding Customer Service
Guards usually available at short notice throughout UK
Please click on the images above or below to download the application form
Latest News
The advert on 'Indeed' which is using our name is a SCAM and is absolutely nothing to do with HG Security & Property Protection Ltd, so DO NOT APPLY!
Revised training courses for new SIA licence applications in 2015
There are many different varieties of this door lock, but many of them are restricted to doors up to a maximum of 65mm thick. Ours is different – a 70mm door is no problem.
Which one gives your property the best protection?
Do you want cheap security, or do you want effective security from a reliable, established company?
Have A Question For Us?
Freephone 0800 7838645
or telephone 01547 560022 fax 01547 560026
Admin Mon-Fri 0900-1730
HG Security & Property Protection Ltd
Head Office
Patton Court, Horseyard House, Evenjobb, Powys LD8 2SA


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Definitions for jade plant
This page provides all possible meanings and translations of the word jade plant
We couldn't find a direct definition for the term jade plant.
Maybe you were looking for one of these terms?
jadding, jade, jade emperor, jade gate, jade green, jade stalk, jade vine, jade-green, jaded, jadedly


text:
Atlanta, GA (PRWEB) May 21, 2013
Patients of Dr. Michael Shenk and Dr. Judd Shenk of Shenk Dental Care who have lost teeth due to gum disease and would like permanent tooth replacements now have alternatives to traditional surgery for gum disease treatment with laser gum surgery. Gum disease must be treated prior to dental implants, which have the highest success rate out of all tooth replacement options.
The Laser Assisted New Attachment Procedure (LANAP) is a relatively new procedure cleared by the Food and Drug Administration (FDA) that greatly improves patients' overall gum health. It has shown to be effective in treating gum disease and also regenerating bone growth. Both of these benefits are huge advantages in cases where dental implants are needed. Before an implant can be placed, there needs to be sufficient bone available to attach the implant to. Additionally, an implant cannot be placed in diseased gums, as it would not take proper hold and the positioning of any dental implants would only push any bacteria or other disease further down the gum tissue and closer to the bone.
Gum disease has historically been treated by traditional surgical methods. These methods are quite effective overall, but have a much higher rate of pain and side effects as well as a much longer recovery time. Additionally, scalpel gum surgery removes a greater amount of gum tissue, including healthy tissue, than laser gum surgery. The latter is able to identify and target only diseased tissue and leave any and all healthy gum tissue completely intact. This reduces the need for further reconstructive procedures dow
|Source: PRWeb
Copyright©2012 Vocus, Inc.
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Mudanjiang Long Term Stay Hotels
Displaying 1 Hotels in Mudanjiang
More IHG Hotels in Mudanjiang
Holiday Inn Mudanjiang
Hold your lavish event in the largest function room in the city at Holiday Inn Mudanjiang. The 1,000-sq-metre, flexible venue can cater for 800 guests in a theatre style, and seat 600 for your grand banquet.
4.4 /5 (69 reviews)
No.1 West Diming Street, Mudanjiang, HJ 157011, China, People's Republic of
Hotel Reservations : 877 226 3539 | Hotel Front Desk : 86-453-8293288


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Stay up-to-date with our quarterly SRT E-NEWS, featuring the latest news, features, events, photos and conservation inspiration via the convenience of email!Subscribe
Earth Day 5K Trail Run & Walk
It's time for Sequoia Riverlands Trust's 6th Annual Earth Day 5K Trail Run at Kaweah Oaks Preserve. Bring friends, family, and colleagues to this spectacular event, and experience one of the last remaining valley oak riparian forests in the San Joaquin Valley!
After the race, check out the City of Visalia's Earth/Arbor Day events, with workshops, a planting project, live music, and more.
What: 5K Trail Run/Walk at Kaweah Oaks Preserve (KOP).
Print a Registration Form and Deliver to Sole 2 Soul
Packet Pickup: You can avoid the lines by picking up your packet (shirt, race bib number, etc.) at our packet pickup.
Packet pickup will be held on April 24th from 12 noon - 7 p.m. at:
Sole 2 Soul Sports
4241 S. Mooney Blvd
Visalia, CA 93277
What's included with your registration:
An Earth Day 5K Trail Run through the beautiful natural terrain course at Kaweah Oaks Preserve.
Each registered participant will receive a commemorative 5k Earth Day shirt (guaranteed to those who registered by April 13th)
- After race snacks and refreshments.
Awards for overall winner (male & female) and 10-year age increments.
All kids (12 and under) will receive a race medal at the finish line of the event.
Knowing that you are supporting valuable conservation and education efforts in the San Joaquin Valley.
Thank you to our sponsors:


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About Mongolia:
Mongolia is a landlocked country located between China and Russia. History and culture abound in Mongolia and outside the main cities many Mongolians continue to live the traditional life of the malchin (herdsmen). Mongolia may have geopolitical, cultural and geographical meanings. Mongolia consists of historic Outer Mongolia. The province of Inner Mongolia is geographically and politically separate and located in northern part of China yet it shares common borders with Mongolia. Mongolia is nicknamed the "Land of Blue Skies," and with good reason: there are said to be about 250 sunny days throughout each year, so you will need good UV protection.
Mongolia is the 19th largest and the most sparsely populated independent country in the world. The predominant religion in Mongolia is Tibetan Buddhism. Islam is the dominant religion among ethnic Kazakhs. Mongolia is a parliamentary republic. The president is directly elected. The people also elect the deputies in the national assembly, the State Great Khural, which chooses the prime minister, who nominates the Cabinet in consultation with the president. Mongolia is also known as the "Land of the horse" and "Steppe Mongolia" and Mongols have a reputation for being the best horsemen on Earth.
Nature: The geography of Mongolia is varied, with the Gobi Desert to the south and with cold and mountainous regions to the north and west. Much of Mongolia consists of steppes, with forested areas comprising 11.2% of the total land area. The highest point in Mongolia is the Khuiten Peak. The basin of the Uvs Lake, shared with Tuva Republic in Russia, is a natural World Heritage Site. There are several hundred lakes in the country and numerous rivers, of which the Orkhon is the longest at 1,124km. The Khangai Mountains play a certain role in forming this microclimate. . A unique microclimate is the fertile grassland-forest region of central and eastern Arkhangai Province and northern Ovorkhangai Province. The country is drained by numerous rivers, including the Hovd, Onon, Selenga, and Tula. Much of the Gobi Desert falls within Mongolia.
Geography: Mongolia lies in central Asia between Siberia on the north and China on the south. It is slightly larger than Alaska. It is border with the Russian Federation in the north and a 4,670km (2,902-mile) border with China in the south. From north to south, it can be divided into four areas: mountain-forest steppe, mountain steppe and, in the extreme south, semi-desert and desert (the latter being about 3% of the entire territory). The majority of the country has a high elevation, with the principal mountains concentrated in the west.
Capital city: Ulan Bator is the capital and the largest city of Mongolia. The city was founded in 1639 as a movable Buddhist monastic centre. Ulan Bator grew into a major manufacturing centre Ulan Bator has been given numerous names in its history. When the city became the capital of the new Mongolian People's Republic in 1924, its name was changed to Ulan Bator. The city is chilly, dry and remote city has had numerous names throughout its history and was renamed. For a long time in a state of disrepair because under Communist rule funds weren't spent on repairs, the architecture is dull, there is rubble lining some of the streets and the transportation is dated - but the history is rich and colourful. is the main street and it stretches from east to west through the center. Peace Avenue It's the main shopping street and many of the restaurants are along it. The street also passes by the southern edge of the central square, Sukhbaatar Square are the main tourist attraction of the country.
Flora and Fauna: The wildlife flourishes in Mongolia despite an extreme climate, the nomadic fondness for hunting, the communist persecution of Buddhists who had set aside areas as animal sanctuaries, and a penniless government, which lacks resources to police nature protection laws. Mongolia is home to over 400 species of birds. In the desert you may see the desert warbler, houbara bustard and saxaul sparrow, as well as sand grouse, finch and the cinereous vulture. According to conservationists, 28 species of mammals are endangered. The more commonly known species are the wild ass, wild camel, Gobi argali sheep, Gobi bear, ibex and the black-tailed gazelle; others include otters, wolves, antelopes and jerboas. The area around Bog khan Uul mountain, near Ulaanbaatar, was protected from hunting and logging as early as the 12th century, and was officially designated as a national park over 200 years ago.
Tourisms: Mongolia's vast areas of wilderness, from the sprawling Gobi desert to the snow peaked mountains of the Bayan-Olgi, offer plenty of scope for adventurous outdoor enthusiasts. Fishing, jeep tours, horse and camel riding, mountain biking and birdwatching Ulaanbaatar is fast transforming itself into a modern city with international restaurants, luxury hotels, shopping malls and glass tower blocks - a sure sign of Mongolia's status as an up-and-coming Asian travel hotspot. Transporting their goods by camel and residing in portable felt and canvas tents, the nomadic lifestyle of modern-day Mongolia would still be recognisable to Ghengis Khan, the most famous Mongol of them all. The main festival is world-famous Naadam, which has been organised for centuries and is held on July 11 to July 13 in honor of the Democratic Revolution. Naadam consists of three Mongolian traditional sports: archery, long-distance horse-racing, and Mongolian wrestling.
Shopping and Nightlife: The notorious Naran Market on the outskirts of Ulaanbaatar is a large, crowded flea market which sells a huge variety of items. Suitable for the adventurous traveller, it is patronised mainly by local people. Ulaanbaatar is well-endowed with antique stores and souvenir shops. Best buys include landscape paintings, cashmere garments, camel-wool blankets, national costumes, boots, jewellery, carpets, books and handicrafts. Nightlife in Mongolia is varied, with evening performances at the State Opera and Ballet Theatre, State Drama Theatre and Puppet Theatre. The Moonstone Song & Dance Ensemble perform at Tsuki House. Ulaanbaatar is teeming with bars, discos and restaurants. The best places to hear live music are River Sounds (Choidog Street) and Grand Khaan Irish Pub (Seoul Street).
Regions In Mongolia
Regions within Mongolia:


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Dalton, offense let Bengals down again in playoffs
Updated: January 7, 2013, 4:44 PM ETAssociated Press
CINCINNATI -- Coach Marvin Lewis was taken aback by the way his team fell apart.
The Bengals played their worst all-around game in months, resulting in a 19-13 loss to Houston on Saturday in a wild card playoff. Even then, they had a chance to win it at the end, but Andy Dalton overthrew an open A.J. Green in the end zone.
After winning seven of their last eight games, the Bengals were convinced they would finally snap one of the most enduring streaks of playoff futility. Instead, ...
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- McShay: Mariota moves up in Mock Draft 4.0
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Rating: I expected a higher quality hotel after reading the other reviews, but this is definitely no more than a 3-star (I believe it's rated a 4-star by whatever local rating service is used).
Staffing: during my 2-day visit the staff was excellent...from the front desk, to the restaurant lunch service staff, to room service, all seemed genuinely helpful.
Cons: 1) a lack of hot water in the morning. While there was no lack of hot water when I took a shower each evening, mornings were an entirely different story. The best the shower could offer up both mornings was what might be considered lukewarm - and that's being generous.
2) Each room has a terrace with bamboo type slats for roofing which does not provide any protection from the rain, preventing use during inclement weather.
Pros: 1) Great SPA. The Stress Reliever hot rock massage was so relaxing - wish I had had more time to take advantage of some of the other treatments offered. If the hotel had been as nice as the SPA, I'd have given it 5-stars.
2) There is a lovely pool with a large wooden deck and jacuzzi, but the temperature during my stay was far too cold to even consider taking a dip.
Buffet: The dinner buffet started at 8 pm, typical for Argentinian restaurants, but I was too exhausted by that time to give it a try.
Internet: I didn't take my computer, since this was a short sight-seeing trip so can not speak to internet speed, but there were two computers in the lobby available for personal use.
If I went again would I stay here, probably not if I booked my own hotel, but this was part of a tour package with limited selection.
- Official Description (provided by the hotel):
- Tourbillon Hotel is located on National Route 12, KM 4,5, 5 minutes from downtown Puerto Iguazu and only 15 minutes from the Falls and Iguazu International Airport. Services: swimming pool, solarium and Jacuzzi, Pool Snack Bar, Lobby Bar, Restaurant with à la carte menu and buffet, Play room, Internet center, Wi-Fi, Laundry, Free Parking, Tours & Transfers. The Hotel has 28 comfortable rooms, 24 Triple Garden and 4 Suite Junior with view to the garden or pool. Services: Air conditioning cold-hot, Telephone, Internet WI-FI, jacuzzy, hair dryer, cable TV with 32 "LCD, Minibar, Room Service, Safe Box, laundry, and private balcony with table and chairs. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Expedia, Travelocity, Odigeo, Priceline, Hotels.com, Agoda and Low Cost Holidays so you can book your Gran Hotel Tourbillon reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.


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Climbing – Kayaking – Bushcraft – Team building – Obstacle course
Zip wire – Raft building – Archery – Bouldering – Hiking – Camping
We transform the lives of disadvantaged children and young people through outdoor education and adventure.
Surplus from our adult activities help us to provide the specialist support many children need to take part.
Group Bookings for Schools and community youth groups
We run after-school activities, Woodland adventure days and camps, indoor and outdoor climbing and more for schools and youth groups and can even bring activities to you.
Current Free & Low Cost Projects:
Are you or do you work with a group who are…
- School in Brighton and Hove who have students ages 8-12 – check out WildZone
- Aged 8+ and live in Phoenix area in Brighton, Portslade, Haywards Heath, Littlehampton or Redhill? Check out New Heights
We provide:
Free and subsidised places for projects – We think all children and young people should be able to access our positive developmental activities, so we provide free and reduced price places for children and young people who otherwise wouldn't be able to take part.
Access for people with disabilities – Having a disability shouldn't stop people taking part. That's why a number of our activities, including our climbing wall, are accessible to everyone—including wheelchair users.
Transport – Access to nature is essential for our wellbeing, but transport can be limited. We provide transport on our days out, because our beneficiaries told us they couldn't always take part without it.
Specialist equipment – We provide all the equipment people need, because otherwise it would be too expensive for many people to take part.
High staff ratios – Our specially trained staff and volunteers are experienced in supporting children and young people with additional needs. We provide lots of them to make sure everyone gets the support they need.
Adventure Unlimited is a registered charity based in Brighton & Hove.


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Select Local Merchants
Coronado Beauty SalonRead MoreCoronado Beauty Salon in Coronado understands how stressful life can be and that's why they offer a large selection of stress-relieving spa treatments. Rejuvenate your skin with a facial from this spa and leave feeling silky smooth. Reap the benefits of a professional skin care treatment from Coronado Beauty Salon, such as chemical peel, facial peels, and microdermabrasion. Pay attention to your body's needs and indulge in a relaxing massage, such as deep tissue and Swedish. With the beauty products selection at this establishment, you can keep your look on point. For beautifully painted and well-maintained nails, try one of the nail services offered at this spa. If you're leaning toward an alternative service, such as reflexology and reiki, look no further than this spa. Keep up with the latest and greatest hairstyles and schedule your next hair makeover today. Coronado Beauty Salon offers hair removal services for unwanted hair on your body and face. Looking for a salon that accommodates walk-ins? Look no further than this establishment. The amenities here may be worth a million bucks, but the prices are rather reasonable. Coronado Beauty Salon offers a wide variety of payment options, including payment by major credit card. Customers at Coronado Beauty Salon will love the simple and nearby street parking options. Renew your mind, body, and soul with a quick trip to Coronado Beauty Salon, and start your week off right.1010 C AveCoronado, CA US
Lavender Flower Day SpaRead MoreBoth men and women can find professional spa services to suit their needs at Lavender Flower Day Spa in Coronado. Keep those pores clear with a relaxing facial courtesy of the spa's expert aestheticians. Experience a new and professional massage treatment, including Shiatsu, deep tissue, and Swedish. If you're looking for the most current on-trend hairstyles, swing in this salon and enjoy a new 'do. If you're looking for a gentle and beneficial alternative remedy, browse the selection of treatments that this spa has to offer. Buff and polish your nails with one of this spa's nail services, such as pedicures and manicures. Take control of your health and wellness with an acupuncture service from Lavender Flower Day Spa. For your convenience and last-minute beauty emergencies, this spa offers walk-ins. If you love to be pampered, you will love the affordable spa service prices and this establishment even more. When you come to Lavender Flower Day Spa, you can leave the cash at home. All major credit cards accepted and welcomed. Drivers can find a space for their wheels on the street at the spa's Orange Avenue business. Plan your next spa day at Lavender Flower Day Spa and see what customers are raving about!1330 Orange AvenueCoronado, CA US
Coronado Cosmetic Surgery CenterRead MoreWhat services does your business offer and what makes your business stand out from the competition? Living in Southern California, it is hard to avoid the sun. Unfortunately, those hours of exposure can effect your skin. At Coronado Cosmetic Surgery center, we are passionate about helping our patients reveal their true beauty by eliminating their brown spots from their face, chest, and hands. What was the inspiration to start or run this business? We are dedicated to providing you a comprehensive, contemporary, and caring cosmetic services in beautiful Coronado, California. We specialize in surgical and non-surgical aesthetic, reconstructive and rejuvenating procedures for men and women. What do you love most about your job? Our promise to you is to carefully explain all of your treatment options and develop a customized and personal plan for your desired outcome for the best results possible. What is the best reaction you've ever gotten from a customer? "My recovery was so easy and the results are nothing short of amazing. My husband is very impressed and I am thrilled!"230 Prospect PlaceCoronado, CA US
Sanctuary Salon and SpaRead MoreSanctuary Salon and Spa understands that when life is getting you down, you take joy out of taking control of your style. You'll be beyond elated with so many services offered in Coronado. Clear up your skin with a relaxing and rejuvenating facial. The professional stylists at this salon are readily available for all of your hair care needs, such as haircuts and coloring processes. Improve the look and feel of your nails with a full-service mani and pedi from this salon. Battling a pesky knot? Relieve the pain and tension with a massage from this salon. This salon in Coronado is walk-in friendly, making it a hit for frequent salon-goers. A spa day filled with relaxing treatments doesn't have to cost you a fortune. Head to Sanctuary Salon and Spa for moderate prices and relaxing services. This establishment will happily accept your major credit card as a form of payment. Pull up curbside and find simple street parking near Sanctuary Salon and Spa. Sanctuary Salon and Spa is a salon fully equipped to handle all of your beauty needs. Give them a call today.874 Orange AveCoronado, CA US
Orchid Day SpaRead MoreSpend a day relaxing with your friends and family at Coronado's Orchid Day Spa, a day spa that caters to both men and women. This spa's expert aestheticians are trained to provide the best and relaxing facials. Keep up with the latest and greatest hairstyles and schedule your next hair makeover today. Applying firm-yet-gentle pressure, the staff at this spa is here to assist you with your massage needs. Perfect your nails with a cleaning treatment and a new coat of polish from this spa. You're in luck! This spa always accepts walk-ins for all beauty services and treatments. This spa offers similar prices to those in the area, but the services are one-of-a-kind. Paying by major credit card is always a payment option at this highly-rated establishment. Park on the street for easy access to Orchid Day Spa. For those extra tough times, Orchid Day Spa is there to help restore calm and balance to your mind and body, so feel free to stop by when you need it most.1033 B AveCoronado, CA US
Coronado Bliss Salon and SpaRead MorePamper yourself with one of the many spa packages at Coronado Bliss Salon and Spa in Coronado. Hydrate and nourish your skin with a custom facial from this salon. Coronado Bliss Salon and Spa has a comfortable atmosphere for all your beauty needs, such as make up application. Tired of unwanted hair quickly growing back? Keep the hair gone longer with a hair removal service from Coronado Bliss Salon and Spa. If you're looking for the most current on-trend hairstyles, swing in this salon and enjoy a new 'do. This salon understands that your time is valuable and that's why it offers an appointment-only policy. If you're looking to rack up your frequent flyer miles, feel free to pay by major credit card. Street parking is the only parking option close to Coronado Bliss Salon and Spa. When you make an appointment at Coronado Bliss Salon and Spa, you're investing in quality service and a beauty that cannot help but turn heads.930 Orange AveCoronado, CA US


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On July 03 2014 at Ottawa, Ontario, Canada 68 Views
View all photos »
female -1938 PhotosOttawa, Ontario, Canada
As fotos DEVEM ser um registro fiel do objeto e momento que dá nome ao grupo (Pôr-do-sol);
pertaining to,
intended for,
or found in a garden"
...from the American Heritage Dictionary
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Shannon Scott
Faculty of Nursing6-133 Clinical Sciences Building
Faculty of Nursing
University of Alberta
Edmonton, AB
Curriculum Vitae
- Associate Professor
- Knowledge Translation
Subject areas and related deposits
Allied health
Systematic review on knowledge translation strategies in the allied health professions
Background: Knowledge translation (KT) aims to close the research-practice gap in order to realize and maximize the benefits of research within the practice setting. Previous studies have investigated KT strategies in nursing and medicine; however, the present study is the first systematic review of the effectiveness of a variety of KT interventions in five allied health disciplines: dietetics, occupational therapy, pharmacy, physiotherapy, and speech-language pathology. Methods: A health research librarian developed and implemented search strategies in eight electronic databases (MEDLINE, CINAHL, ERIC, PASCAL, EMBASE, IPA, Scopus, CENTRAL) using language (English) and date restrictions (1985 to March 2010). Other relevant sources were manually searched. Two reviewers independently screened the titles and abstracts, reviewed full-text articles, performed data extraction, and performed quality assessment. Within each profession, evidence tables were created, grouping and analyzing data by research design, KT strategy, targeted behaviour, and primary outcome. The published descriptions of the KT interventions were compared to the Workgroup for Intervention Development and Evaluation Research (WIDER) Recommendations to Improve the Reporting of the Content of Behaviour Change Interventions. Results: A total of 2,638 articles were located and the titles and abstracts were screened. Of those, 1,172 full-text articles were reviewed and subsequently 32 studies were included in the systematic review. A variety of single (n = 15) and multiple (n = 17) KT interventions were identified, with educational meetings being the predominant KT strategy (n = 11). The majority of primary outcomes were identified as professional/process outcomes (n = 25); however, patient outcomes (n = 4), economic outcomes (n = 2), and multiple primary outcomes (n = 1) were also represented. Generally, the studies were of low methodological quality. Outcome reporting bias was common and precluded clear determination of intervention effectiveness. In the majority of studies, the interventions demonstrated mixed effects on primary outcomes, and only four studies demonstrated statistically significant, positive effects on primary outcomes. None of the studies satisfied the four WIDER Recommendations. Conclusions: Across five allied health professions, equivocal results, low methodological quality, and outcome reporting bias limited our ability to recommend one KT strategy over another. Further research employing the WIDER Recommendations is needed to inform the development and implementation of effective KT interventions in allied health.Download
- Systematic review on knowledge translation strategies in the allied health professions
Behavior change intervention reporting
Development of a checklist to assess the quality of reporting of knowledge translation interventions using the workgroup for intervention development and evaluation research (WIDER) recommendations.
Background Influenced by an important paper by Michie et al., outlining the rationale and requirements for detailed reporting of behavior change interventions now required by Implementation Science, we created and refined a checklist to operationalize the Workgroup for Intervention Development and Evaluation Research (WIDER) recommendations in systematic reviews. The WIDER recommendations provide a framework to identify and provide detailed reporting of the essential components of behavior change interventions in order to facilitate replication, further development, and scale-up of the interventions. Findings The checklist was developed, applied, and improved over the course of four systematic reviews of knowledge translation (KT) strategies in a variety of healthcare settings conducted by Scott and associates. The checklist was created as one method of operationalizing the work of the WIDER in order to facilitate comparison across heterogeneous studies included in these systematic reviews. Numerous challenges were encountered in the process of creating and applying the checklist across four stages of development. The resulting improvements have produced a 'user-friendly' and replicable checklist to assess the quality of reporting of KT interventions in systematic reviews using the WIDER recommendations. Conclusions With journals, such as Implementation Science, using the WIDER recommendations as publication requirements for evaluation reports of behavior change intervention studies, it is crucial to find methods of examining, measuring, and reporting the quality of reporting. This checklist is one approach to operationalize the WIDER recommendations in systematic review methodology.Download
- Development of a checklist to assess the quality of reporting of knowledge translation interventions using the workgroup for intervention development and evaluation research (WIDER) recommendations.
Biomedical research
Education in health research methodology: Use of a wiki for knowledge translation.
Introduction A research-practice gap exists between what is known about conducting methodologically rigorous randomized controlled trials (RCTs) and what is done. Evidence consistently shows that pediatric RCTs are susceptible to high risk of bias; therefore novel methods of influencing the design and conduct of trials are required. The objective of this study was to develop and pilot test a wiki designed to educate pediatric trialists and trainees in the principles involved in minimizing risk of bias in RCTs. The focus was on preliminary usability testing of the wiki. Methods The wiki was developed through adaptation of existing knowledge translation strategies and through tailoring the site to the identified needs of the end-users. The wiki was evaluated for usability and user preferences regarding the content and formatting. Semi-structured interviews were conducted with 15 trialists and systematic reviewers, representing varying levels of experience with risk of bias or the conduct of trials. Data were analyzed using content analysis. Results Participants found the wiki to be well organized, easy to use, and straightforward to navigate. Suggestions for improvement tended to focus on clarification of the text or on esthetics, rather than on the content or format. Participants liked the additional features of the site that were supplementary to the text, such as the interactive examples, and the components that focused on practical applications, adding relevance to the theory presented. While the site could be used by both trialists and systematic reviewers, the lack of a clearly defined target audience caused some confusion among participants. Conclusions Participants were supportive of using a wiki as a novel educational tool. The results of this pilot test will be used to refine the risk of bias wiki, which holds promise as a knowledge translation intervention for education in medical research methodology.Download
- Education in health research methodology: Use of a wiki for knowledge translation.
Child health
A Randomized Controlled Trial of Storytelling as a Communication Tool.
Introduction Stories may be an effective tool to communicate with patients because of their ability to engage the reader. Our objective was to evaluate the effectiveness of story booklets compared to standard information sheets for parents of children attending the emergency department (ED) with a child with croup. Methods Parents were randomized to receive story booklets (n=208) or standard information sheets (n=205) during their ED visit. The primary outcome was change in anxiety between triage to ED discharge as measured by the State-Trait Anxiety Inventory. Follow-up telephone interviews were conducted at 1 and 3 days after discharge, then every other day until 9 days (or until resolution of symptoms), and at 1 year. Secondary outcomes included: expected future anxiety, event impact, parental knowledge, satisfaction, decision regret, healthcare utilization, time to symptom resolution. Results There was no significant difference in the primary outcome of change in parental anxiety between recruitment and ED discharge (change of 5 points for the story group vs. 6 points for the comparison group, p=0.78). The story group showed significantly greater decision regret regarding their decision to go to the ED (p<0.001): 6.7% of the story group vs. 1.5% of the comparison group strongly disagreed with the statement "I would go for the same choice if I had to do it over again". The story group reported shorter time to resolution of symptoms (mean 3.7 days story group vs. 4.0 days comparison group, median 3 days both groups; log rank test, p=0.04). No other outcomes were different between study groups. Conclusions Stories about parent experiences managing a child with croup did not reduce parental anxiety. The story group showed significantly greater decision regret and quicker time to resolution of symptoms. Further research is needed to better understand whether stories can be effective in improving patient-important outcomes.Download
- A Randomized Controlled Trial of Storytelling as a Communication Tool.
Understanding implementation processes of clinical pathways and clinical practice guidelines in pediatric contexts: A study protocol
Background: Canada is among the most prosperous nations in the world, yet the health and wellness outcomes of Canadian children are surprisingly poor. There is some evidence to suggest that these poor health outcomes are partly due to clinical practice variation, which can stem from failure to apply the best available research evidence in clinical practice, otherwise known as knowledge translation (KT). Surprisingly, clinical practice variation, even for common acute paediatric conditions, is pervasive. Clinical practice variation results in unnecessary medical treatments, increased suffering, and increased healthcare costs. This study focuses on improving health outcomes for common paediatric acute health concerns by evaluating strategies that improve KT and reduce clinical practice variation. Design/Methods: Using a multiple case study design, qualitative and quantitative data will be collected from four emergency departments in western Canada. Data sources will include: pre and post implementation focus group data from multidisciplinary healthcare professionals; individual interviews with the local champions, KT intervention providers, and unit/site leaders/managers; Alberta Context Tool (ACT) survey data; and aggregated patient outcome data. Qualitative and quantitative data will be systematically triangulated, and matrices will be built to do cross-case comparison. Explanations will be built about the success or lack of success of the clinical practice guidelines (CPG) and clinical pathways (CPs) uptake based upon the cross-case comparisons. Significance: This study will generate new knowledge about the potential causal mechanisms and factors which shape implementation. Future studies will track the impact of the CPG/CPs implementation on children's health outcome, and healthcare costs.Download
- Understanding implementation processes of clinical pathways and clinical practice guidelines in pediatric contexts: A study protocol
Unresolved pain in children: an ethical perspective
It is considered the right of children to have their pain managed effectively. Yet, despite extensive research findings, policy guidelines and practice standard recommendations for the optimal management of paediatric pain, clinical practices remain inadequate. Empirical evidence definitively shows that unrelieved pain in children has only harmful consequences, with no benefits. Contributing factors identified in this undermanaged pain include the significant role of nurses. Nursing attitudes and beliefs about children's pain experiences, the relationships nurses share with children who are suffering, and knowledge deficits in pain management practices are all shown to impact unresolved pain in children. In this article, a relational ethics perspective is used to explore the need for nurses to engage in authentic relationships with children who are experiencing pain, and to use evidence-based practices to manage that pain in order for this indefensible suffering of children to end.Download
Clinical pathways
Best strategies to implement clinical pathways in an emergency department setting: Study protocol for a cluster randomized controlled trial.
Background The clinical pathway is a tool that operationalizes best evidence recommendations and clinical practice guidelines in an accessible format for 'point of care' management by multidisciplinary health teams in hospital settings. While high-quality, expert-developed clinical pathways have many potential benefits, their impact has been limited by variable implementation strategies and suboptimal research designs. Best strategies for implementing pathways into hospital settings remain unknown. This study will seek to develop and comprehensively evaluate best strategies for effective local implementation of externally developed expert clinical pathways. Design/methods We will develop a theory-based and knowledge user-informed intervention strategy to implement two pediatric clinical pathways: asthma and gastroenteritis. Using a balanced incomplete block design, we will randomize 16 community emergency departments to receive the intervention for one clinical pathway and serve as control for the alternate clinical pathway, thus conducting two cluster randomized controlled trials to evaluate this implementation intervention. A minimization procedure will be used to randomize sites. Intervention sites will receive a tailored strategy to support full clinical pathway implementation. We will evaluate implementation strategy effectiveness through measurement of relevant process and clinical outcomes. The primary process outcome will be the presence of an appropriately completed clinical pathway on the chart for relevant patients. Primary clinical outcomes for each clinical pathway include the following: Asthma—the proportion of asthmatic patients treated appropriately with corticosteroids in the emergency department and at discharge; and Gastroenteritis—the proportion of relevant patients appropriately treated with oral rehydration therapy. Data sources include chart audits, administrative databases, environmental scans, and qualitative interviews. We will also conduct an overall process evaluation to assess the implementation strategy and an economic analysis to evaluate implementation costs and benefits. Discussion This study will contribute to the body of evidence supporting effective strategies for clinical pathway implementation, and ultimately reducing the research to practice gaps by operationalizing best evidence care recommendations through effective use of clinical pathways.Download
- Best strategies to implement clinical pathways in an emergency department setting: Study protocol for a cluster randomized controlled trial.
Clinical trials as topic
Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building upon the results of a quantitative survey. We surveyed Canadian (n=253) and international (n=600) pediatric trialists regarding their knowledge and awareness of bias and their perceived barriers and facilitators in conducting clinical trials. We then interviewed 13 participants from different subspecialties and geographic locations to gain a more detailed description of how their experiences and attitudes towards research interacted with trial design and conduct. Results The survey response rate was 23.0% (186/807). 68.1% of respondents agreed that bias is a problem in pediatric RCTs and 72.0% felt that there is sufficient evidence to support changing some aspects of how trials are conducted. Knowledge related to bias was variable, with inconsistent awareness of study design features that may introduce bias into a study. Interview participants highlighted a lack of formal training in research methods, a negative research culture, and the pragmatics of trial conduct as barriers. Facilitators included contact with knowledgeable and supportive colleagues and infrastructure for research. Conclusions A lack of awareness of bias and negative attitudes towards research present significant barriers in terms of conducting methodologically rigorous pediatric RCTs. Knowledge translation efforts must focus on these issues to ensure the relevance and validity of trial results.Download
- Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Diffusion of Innovation
Does the workplace influence nurses' use of research?
Building on the work of Ehrenberg and Estabrooks, the authors continue the series of articles on knowledge utilization by focusing on the effect of organizational factors and leadership on research use by individual practitioners. Traditionally, the onus to integrate research findings into everyday practice has been placed on the individual practitioner. This tendency to blame the individual practitioner is consistent with the era of personal and professional responsibility. The research-practice gap is believed to exist because the knowledge and behaviors of individuals, including research skills and educational preparation, were inadequate. However, a recent systematic review of the research literature examining what determines individual's use of research revealed inconsistent results and found only one consistent individual determinant of research use: attitude toward research use. Also, many individual determinants are not easy to change (eg, age and gender). These results question the validity of conclusions and recommendations of many of the studies in this research area. Investigators are now beginning to suggest that the organization holds a more significant role in impeding or promoting the move to evidence-based practice and that organizational context is a potentially important factor in determining research use. However, the how and why organizational context is important are still unanswered questions. Consequently, there have been calls for further investigation into the role that organizational context plays in research use.Download
- Does the workplace influence nurses' use of research?
Learning peer review: Is jumping into the "deep end" the best approach?
Peer review is the essence of scholarship, embodying unique disciplinary expertise and the altruism to painstakingly enhance a manuscript for an anonymous author. In fact, peer review has been termed "a gift of uncompensated time from scientists to whom time is a precious commodity" (Scott-Lichter & Editorial Policy Committee, 2012, p. 5). Peer review is a learned skill evolving as scholars and clinicians become comfortable in their "professional skins." And, like all learned skills, peer review must begin somewhere, with novice skills preceding expertise. Given the critical nature of peer review to advance disciplinary art and science, it is remarkable that formal education in this area is largely absent.Download
- Learning peer review: Is jumping into the "deep end" the best approach?
Evidence based medicine
The intellectual structure and substance of the knowledge utilization field: A longitudinal author co-citation analysis, 1945-2004
Background: It has been argued that science and society are in the midst of a far-reaching renegotiation of the social contract between science and society, with society becoming a far more active partner in the creation of knowledge. On the one hand, new forms of knowledge production are emerging, and on the other, both science and society are experiencing a rapid acceleration in new forms of knowledge utilization. Concomitantly since the Second World War, the science underpinning the knowledge utilization field has had exponential growth. Few in-depth examinations of this field exist, and no comprehensive analyses have used bibliometric methods. Methods: Using bibliometric analysis, specifically first author co-citation analysis, our group undertook a domain analysis of the knowledge utilization field, tracing its historical development between 1945 and 2004. Our purposes were to map the historical development of knowledge utilization as a field, and to identify the changing intellectual structure of its scientific domains. We analyzed more than 5,000 articles using citation data drawn from the Web of Science (R). Search terms were combinations of knowledge, research, evidence, guidelines, ideas, science, innovation, technology, information theory and use, utilization, and uptake. Results: We provide an overview of the intellectual structure and how it changed over six decades. The field does not become large enough to represent with a co-citation map until the mid-1960s. Our findings demonstrate vigorous growth from the mid-1960s through 2004, as well as the emergence of specialized domains reflecting distinct collectives of intellectual activity and thought. Until the mid-1980s, the major domains were focused on innovation diffusion, technology transfer, and knowledge utilization. Beginning slowly in the mid-1980s and then growing rapidly, a fourth scientific domain, evidence-based medicine, emerged. The field is dominated in all decades by one individual, Everett Rogers, and by one paradigm, innovation diffusion. Conclusion: We conclude that the received view that social science disciplines are in a state where no accepted set of principles or theories guide research (i.e., that they are pre-paradigmatic) could not be supported for this field. Second, we document the emergence of a new domain within the knowledge utilization field, evidence-based medicine. Third, we conclude that Everett Rogers was the dominant figure in the field and, until the emergence of evidence-based medicine, his representation of the general diffusion model was the dominant paradigm in the field.Download
- The intellectual structure and substance of the knowledge utilization field: A longitudinal author co-citation analysis, 1945-2004
Assessment of Variation in the Alberta Context Tool: The Contribution of Unit Level Contextual Factors and Specialty in Canadian Pediatric Acute Care Settings
Background: There are few validated measures of organizational context and none that we located are parsimonious and address modifiable characteristics of context. The Alberta Context Tool (ACT) was developed to meet this need. The instrument assesses 8 dimensions of context, which comprise 10 concepts. The purpose of this paper is to report evidence to further the validity argument for ACT. The specific objectives of this paper are to: (1) examine the extent to which the 10 ACT concepts discriminate between patient care units and (2) identify variables that significantly contribute to between-unit variation for each of the 10 concepts. Methods: 859 professional nurses (844 valid responses) working in medical, surgical and critical care units of 8 Canadian pediatric hospitals completed the ACT. A random intercept, fixed effects hierarchical linear modeling (HLM) strategy was used to quantify and explain variance in the 10 ACT concepts to establish the ACT's ability to discriminate between units. We ran 40 models (a series of 4 models for each of the 10 concepts) in which we systematically assessed the unique contribution (i.e., error variance reduction) of different variables to between-unit variation. First, we constructed a null model in which we quantified the variance overall, in each of the concepts. Then we controlled for the contribution of individual level variables (Model 1). In Model 2, we assessed the contribution of practice specialty (medical, surgical, critical care) to variation since it was central to construction of the sampling frame for the study. Finally, we assessed the contribution of additional unit level variables (Model 3). Results: The null model (unadjusted baseline HLM model) established that there was significant variation between units in each of the 10 ACT concepts (i.e., discrimination between units). When we controlled for individual characteristics, significant variation in the 10 concepts remained. Assessment of the contribution of specialty to between-unit variation enabled us to explain more variance (1.19% to 16.73%) in 6 of the 10 ACT concepts. Finally, when we assessed the unique contribution of the unit level variables available to us, we were able to explain additional variance (15.91% to 73.25%) in 7 of the 10 ACT concepts. Conclusion: The findings reported here represent the third published argument for validity of the ACT and adds to the evidence supporting its use to discriminate patient care units by all 10 contextual factors. We found evidence of relationships between a variety of individual and unit-level variables that explained much of this between-unit variation for each of the 10 ACT concepts. Future research will include examination of the relationships between the ACT's contextual factors and research utilization by nurses and ultimately the relationships between context, research utilization, and outcomes for patients.Download
- Assessment of Variation in the Alberta Context Tool: The Contribution of Unit Level Contextual Factors and Specialty in Canadian Pediatric Acute Care Settings
Knowledge translation
Optimizing clinical environments for knowledge translation: strategies for nursing leaders
Using findings from our recent study that found that a context of uncertainty in the work environment hindered nurses' research utilization, we suggest strategies for nurse managers and leaders to optimize clinical environments and support efforts to put research into clinical practice (knowledge translation). Two important sources of uncertainty were the complexity of teamwork and inconsistency in management and leadership styles. To reduce the uncertainty arising from teamwork, we propose (a) clarifying nurses' scopes of practice, (b) increasing knowledge sharing through supporting journal clubs and enhanced computer access and (c) creating safe venues for multidisciplinary dialogue. To reduce uncertainty arising from variations in management and leadership, we propose (a) developing policies that enhance the consistency of leadership and clarify the strategic direction of the management team, (b) clearly communicating those policies to nurses and (c) providing explicit rationales for treatment changes. Small, incremental steps can be taken to realize substantive changes in clinical environments in order to optimize nursing work environments for knowledge translation.Download
- Optimizing clinical environments for knowledge translation: strategies for nursing leaders
Protocol for a systematic review of the use of narrative storytelling and visual-arts-based approaches as knowledge translation tools in healthcare.
Background The arts are powerful, accessible forms of communication that have the potential to impart knowledge by attracting interest and developing meaningful connections. Knowledge translation aims to reduce the 'evidence-practice' gap by developing, implementing and evaluating strategies designed to enhance awareness and promote behavior change congruent with research evidence. Increasingly, innovative approaches such as narrative storytelling and other arts-based interventions are being investigated to bridge the growing gap between practice and research. This study is the first to systematically identify and synthesize current research on narrative storytelling and visual art to translate and disseminate health research. Methods A health research librarian will develop and implement search strategies designed to identify relevant evidence. Studies will be included if they are primary research employing narrative storytelling and/or visual art as a knowledge translation strategy in healthcare. Two reviewers will independently perform study selection, quality assessment, and data extraction using standard forms. Disagreements will be resolved through discussion or third party adjudication. Data will be grouped and analyzed by research design, type of knowledge translation strategy (that is, a narrative or visual-arts-based approach), and target audience. An overall synthesis across all studies will be conducted. Discussion The findings from this research project will describe the 'state of the science' regarding the use of narrative storytelling and visual art as knowledge translation strategies. This systematic review will provide critical information for: (1) researchers conducting knowledge translation intervention studies; (2) nursing, medicine, and allied healthcare professionals; (3) healthcare consumers, including patients and families; and (4) decision makers and knowledge users who are charged to increase use of the latest research in healthcare settings.Download
Nurse education
Learning peer review: Is jumping into the "deep end" the best approach?
Peer review is the essence of scholarship, embodying unique disciplinary expertise and the altruism to painstakingly enhance a manuscript for an anonymous author. In fact, peer review has been termed "a gift of uncompensated time from scientists to whom time is a precious commodity" (Scott-Lichter & Editorial Policy Committee, 2012, p. 5). Peer review is a learned skill evolving as scholars and clinicians become comfortable in their "professional skins." And, like all learned skills, peer review must begin somewhere, with novice skills preceding expertise. Given the critical nature of peer review to advance disciplinary art and science, it is remarkable that formal education in this area is largely absent.Download
- Learning peer review: Is jumping into the "deep end" the best approach?
Nurses research utilization
Nursing practice
Patterns of Research Utilization on Patient Care Units
Background: Organizational context plays a central role in shaping the use of research by healthcare professionals. The largest group of professionals employed in healthcare organizations is nurses, putting them in a position to influence patient and system outcomes significantly. However, investigators have often limited their study on the determinants of research use to individual factors over organizational or contextual factors. Methods: The purpose of this study was to examine the determinants of research use among nurses working in acute care hospitals, with an emphasis on identifying contextual determinants of research use. A comparative ethnographic case study design was used to examine seven patient care units (two adult and five pediatric units) in four hospitals in two Canadian provinces (Ontario and Alberta). Data were collected over a six-month period by means of quantitative and qualitative approaches using an array of instruments and extensive fieldwork. The patient care unit was the unit of analysis. Drawing on the quantitative data and using correspondence analysis, relationships between various factors were mapped using the coefficient of variation. Results: Units with the highest mean research utilization scores clustered together on factors such as nurse critical thinking dispositions, unit culture (as measured by work creativity, work efficiency, questioning behavior, co-worker support, and the importance nurses place on access to continuing education), environmental complexity (as measured by changing patient acuity and re-sequencing of work), and nurses' attitudes towards research. Units with moderate research utilization clustered on organizational support, belief suspension, and intent to use research. Higher nursing workloads and lack of people support clustered more closely to units with the lowest research utilization scores. Conclusion: Modifiable characteristics of organizational context at the patient care unit level influences research utilization by nurses. These findings have implications for patient care unit structures and offer beginning direction for the development of interventions to enhance research use by nurses.Download
- Patterns of Research Utilization on Patient Care Units
Pediatric nursing
The influence of organizational context on the use of research by nurses in Canadian pediatric hospitals.
Background Organizational context is recognized as an important influence on the successful implementation of research by healthcare professionals. However, there is relatively little empirical evidence to support this widely held view. Methods The objective of this study was to identify dimensions of organizational context and individual (nurse) characteristics that influence pediatric nurses' self-reported use of research. Data on research use, individual, and contextual variables were collected from registered nurses (N = 735) working on 32 medical, surgical and critical care units in eight Canadian pediatric hospitals using an online survey. We used Generalized Estimating Equation modeling to account for the correlated structure of the data and to identify which contextual dimensions and individual characteristics predict two kinds of self-reported research use: instrumental (direct) and conceptual (indirect). Results Significant predictors of instrumental research use included: at the individual level; belief suspension-implement, research use in the past, and at the hospital unit (context) level; culture, and the proportion on nurses possessing a baccalaureate degree or higher. Significant predictors of conceptual research use included: at the individual nurse level; belief suspension-implement, problem solving ability, use of research in the past, and at the hospital unit (context) level; leadership, culture, evaluation, formal interactions, informal interactions, organizational slack-space, and unit specialty. Conclusions Hospitals, by focusing attention on modifiable elements of unit context may positively influence nurses' reported use of research. This influence of context may extend to the adoption of best practices in general and other innovative or quality interventions.Download
- The influence of organizational context on the use of research by nurses in Canadian pediatric hospitals.
Process evaluation
A protocol for a systematic review of the use of process evaluations in knowledge translation research
Background Experimental designs for evaluating knowledge translation (KT) interventions for professional behavior change can provide strong estimates of intervention effectiveness but offer limited insight how the intervention worked or not. Furthermore, trials provide little insight into the ways through which interventions lead to behavior change and how they are moderated by different facilitators and barriers. As a result, the ability to generalize the findings from one study to a different context, organization, or clinical problem is severely compromised. Consequently, researchers have started to explore the causal mechanisms in complementary studies (process evaluations) alongside experimental designs for evaluating KT interventions. This study focuses on improving process evaluations by synthesizing current evidence on process evaluations conducted alongside experimental designs for evaluating KT interventions. Methods/Design A medical research librarian will develop and implement search strategies designed to identify evidence that is relevant to process evaluations in health research. Studies will not be excluded based on design. Included studies must contain a process evaluation component aimed at understanding or evaluating a KT intervention targeting professional behavior change. Two reviewers will perform study selection, quality assessment, and data extraction using standard forms. Disagreements will be resolved through discussion or third party adjudication. Data to be collected include study design, details about data collection approaches and types, theoretical influences, approaches to evaluate intervention dose delivered, intervention dose received, intervention fidelity, intervention reach, data analysis, and study outcomes. This study is not registered with PROSPERO. Discussion There is widespread acceptance that the generalizability of quantitative trials of KT interventions would be significantly enhanced to other contexts, health professional groups, and clinical conditions through complementary process evaluations alongside trials. This systematic review will serve as a 'state of the science' on methodological approaches to process evaluations and will allow us to: 1) take stock of current research approaches and 2) develop concrete recommendations for knowledge users (e.g., quality consultants and health services researchers) designing future KT process evaluations.Download
- A protocol for a systematic review of the use of process evaluations in knowledge translation research
Research use
Interventions aimed at increasing research use in nursing: A systematic review
Background: There has been considerable interest recently in developing and evaluating interventions to increase research use by clinicians. However, most work has focused on medical practices; and nursing is not well represented in existing systematic reviews. The purpose of this article is to report findings from a systematic review of interventions aimed at increasing research use in nursing. Objective: To assess the evidence on interventions aimed at increasing research use in nursing. Methods: A systematic review of research use in nursing was conducted using databases (Medline, CINAHL, Healthstar, ERIC, Cochrane Central Register of Controlled Trials, and Psychinfo), grey literature, ancestry searching (Cochrane Database of Systematic Reviews), key informants, and manual searching of journals. Randomized controlled trials and controlled before- and after-studies were included if they included nurses, if the intervention was explicitly aimed at increasing research use or evidence-based practice, and if there was an explicit outcome to research use. Methodological quality was assessed using preexisting tools. Data on interventions and outcomes were extracted and categorized using a pre-established taxonomy. Results: Over 8,000 titles were screened. Three randomized controlled trials and one controlled before- and after-study met the inclusion criteria. The methodological quality of included studies was generally low. Three investigators evaluated single interventions. The most common intervention was education. Investigators measured research use using a combination of surveys (three studies) and compliance with guidelines (one study). Researcher-led educational meetings were ineffective in two studies. Educational meetings led by a local opinion leader (one study) and the formation of multidisciplinary committees (one study) were both effective at increasing research use. Conclusion: Little is known about how to increase research use in nursing, and the evidence to support or refute specific interventions is inconclusive. To advance the field, we recommend that investigators: (1) use theoretically informed interventions to increase research use, (2) measure research use longitudinally using theoretically informed and psychometrically sound measures of research use, as well as, measuring patient outcomes relevant to the intervention, and (3) use more robust and methodologically sound study designs to evaluate interventions. If investigators aim to establish a link between using research and improved patient outcomes they must first identify those interventions that are effective at increasing research use.Download
- Interventions aimed at increasing research use in nursing: A systematic review
Scoping review
Social media use among patients and caregivers: A scoping review.
OBJECTIVE: To map the state of the existing literature evaluating the use of social media in patient and caregiver populations. DESIGN: Scoping review. DATA SOURCES: Medline, CENTRAL, ERIC, PubMed, CINAHL Plus Full Text, Academic Search Complete, Alt Health Watch, Health Source, Communication and Mass Media Complete, Web of Knowledge and ProQuest (2000-2012). STUDY SELECTION: Studies reporting primary research on the use of social media (collaborative projects, blogs/microblogs, content communities, social networking sites, virtual worlds) by patients or caregivers. DATA EXTRACTION: Two reviewers screened studies for eligibility; one reviewer extracted data from relevant studies and a second performed verification for accuracy and completeness on a 10% sample. Data were analysed to describe which social media tools are being used, by whom, for what purpose and how they are being evaluated. RESULTS: Two hundred eighty-four studies were included. Discussion forums were highly prevalent and constitute 66.6% of the sample. Social networking sites (14.8%) and blogs/microblogs (14.1%) were the next most commonly used tools. The intended purpose of the tool was to facilitate self-care in 77.1% of studies. While there were clusters of studies that focused on similar conditions (eg, lifestyle/weight loss (12.7%), cancer (11.3%)), there were no patterns in the objectives or tools used. A large proportion of the studies were descriptive (42.3%); however, there were also 48 (16.9%) randomised controlled trials (RCTs). Among the RCTs, 35.4% reported statistically significant results favouring the social media intervention being evaluated; however, 72.9% presented positive conclusions regarding the use of social media. CONCLUSIONS: There is an extensive body of literature examining the use of social media in patient and caregiver populations. Much of this work is descriptive; however, with such widespread use, evaluations of effectiveness are required. In studies that have examined effectiveness, positive conclusions are often reported, despite non-significant findings.Download
- Social media use among patients and caregivers: A scoping review.
Social media
A systematic review of the use and effectiveness of social media in child health.
Background: Social media use is highly prevalent among children, youth, and their caregivers, and its use in healthcare is being explored. The objective of this study was to conduct a systematic review to determine: 1) for what purposes social media is being used in child health and its effectiveness; and 2) the attributes of social media tools that may explain how they are or are not effective. Methods: We searched Medline, CENTRAL, ERIC, PubMed, CINAHL, Academic Search Complete, Alt Health Watch, Health Source, Communication and Mass Media Complete, Web of Knowledge, and Proquest Dissertation and Theses Database from 2000–2013. We included primary research that evaluated the use of a social media tool, and targeted children, youth, or their families or caregivers. Quality assessment was conducted on all included analytic studies using tools specific to different quantitative designs. Results: We identified 25 studies relevant to child health. The majority targeted adolescents (64%), evaluated social media for health promotion (52%), and used discussion forums (68%). Most often, social media was included as a component of a complex intervention (64%). Due to heterogeneity in conditions, tools, and outcomes, results were not pooled across studies. Attributes of social media perceived to be effective included its use as a distraction in younger children, and its ability to facilitate communication between peers among adolescents. While most authors presented positive conclusions about the social media tool being studied (80%), there is little high quality evidence of improved outcomes to support this claim. Conclusions: This comprehensive review demonstrates that social media is being used for a variety of conditions and purposes in child health. The findings provide a foundation from which clinicians and researchers can build in the future by identifying tools that have been developed, describing how they have been used, and isolating components that have been effective.Download
- A systematic review of the use and effectiveness of social media in child health.
Stories – a novel approach to transfer complex health information to parents: A qualitative study
Objective: To identify the beneficial attributes and mechanisms of storytelling through understanding the parental experiences of using a storybook knowledge translation intervention. Method: An exploratory descriptive design involving 23 parents of children presenting to two emergency departments for treatment of croup. Parents received a set of three storybooks, each representing a different severity level of croup (mild, moderate, and severe). Results: The storybooks were evaluated favorably. Parents were better able to understand the progression and treatment of croup by reading the stories, thus reducing uncertainty and alleviating anxiety about their child's condition. Parents consistently reported four positive outcomes associated with using the storybooks: (1) feeling reassured that they had done the right thing, (2) reduced uncertainty, (3) a normalization of the experience, and (4) feeling empowered. Conclusion: The "storybook" presentation of health information was regarded favorably by parents as a learning tool. Practice implications: The storybook format is a useful knowledge translation device.Download
- Stories – a novel approach to transfer complex health information to parents: A qualitative study
Storytelling as a communication tool for health consumers: development of an intervention for parents of children with croup. Stories to communicate health information.
BACKGROUND: Stories may be an effective tool to communicate with and influence patients because of their ability to engage the reader. The objective of this paper is to describe the development of a story-based intervention for delivery of health evidence to parents of children with croup for use in a randomized controlled trial. METHODS: A creative writer interviewed parents of children with croup presenting to the pediatric emergency department (ED) and drafted stories. We revised the stories based on written participant feedback and edited the stories to incorporate research evidence and health information. An illustrator and graphic designer developed story booklets which were evaluated through focus groups. RESULTS: Ten participants provided feedback on the five stories drafted by the creative writer. Participants liked the concept but found the writing overly sophisticated and wanted more character development and more medical/health information. Participants highlighted specific story content that they liked and disliked. The revised stories were evaluated through focus groups involving eight individuals. Feedback was generally positive; one participant questioned the associated costs. Participants liked the graphics and layout; felt that they could identify with the stories; and felt that it was easier to get information compared to a standard medical information sheet. Participants provided feedback on the story content, errors and inconsistencies, and preferences of writing style and booklet format. Feedback on how to package the stories was provided by attendees at a national meeting of pediatric emergency researchers. CONCLUSIONS: Several challenges arose during the development of the stories including: staying true to the story versus being evidence based; addressing the use of the internet by consumers as a source of health information; balancing the need to be comprehensive and widely applicable while being succinct; considerations such as story length, reading level, narrative mode, representation of different demographics and illness experiences, graphics and layout. The process was greatly informed by feedback from the end-user group. This allowed us to shape our products to ensure accuracy, credibility, and relevance. Our experience is valuable for further work in the area of stories and narratives, as well as more broadly for identifying and developing communication strategies for healthcare consumers.Download


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A link would be great. o.o
Idk. My little brother has been playing it. Idk just Pokemon online.
I was wondering if anyone knew a way to hack it. It seems simple enough.
Like it looks real basic & its a new game.
So I would appreciate it if anyone could help me hack this game. Mainly levels, strength & money stuff like that.
I can + rep & i may have something else if some actually finds a sucessful way, but yeah.
Please & ty.
Who ever helps me first with a successful cheat/hack for this game gets 5-6 dollars via paypal.
Not much, but easy money for teh ones that can do this with no problem
Last edited by Fresh; 07-17-2008 at 12:29 PM.
A link would be great. o.o
And it was all so hazy, runnin' round this river town
the time we spent was here,
And it can drive me crazy, thinkin' bout that schoolboy
and how he disappeared
Link added. I thought i added one already sorry.
Just let me know if its possible. if anyone wants to attempt. Let me know & we will discuss.
Last edited by Fresh; 07-16-2008 at 05:07 AM.
This opens several packet editing and memory modifying challenges, this should be interesting.
Curious, is it a executable or a browser related game?
Oh, I see it's a executable, I'll post some scripts for it later.
I'll do it later, it's giving me errors.
Last edited by Cody; 07-16-2008 at 06:07 AM.
Oh ok thanks. I will check back later. I was hoping you would give it a shot.
Last edited by Colin; 07-16-2008 at 04:14 PM.
Signature image hugely excessive in size. - Emperor Freaky
orly freaky, anytime.
You realise that it's adware right?
Tis also really laggy o_O
Signature image hugely excessive in size. - Emperor Freaky
orly freaky, anytime.
"To download and play the Pokemon World Online game you must also download and install Zango. It's free and very easy to install and will give you access to the full game." If you are directed to the site, DO NOT DOWNLOAD the game there at any cost! Zango is an Adware program that forces adverts to appear on your computer and can download other malicious software onto your computer. Using the game offered by onlinepokemongame.info will download Zango to your computer and possibly invade your privacy!
I saw that and read it as you had to install Zango to play.


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Repost: Francis "Frank" J. Underwood From Netflix's House of Cards: A Textbook Case of Antisocial Personality Disorder
By Shaili Jain, MD
Posted: March 4, 2015
Posted: March 4, 2015
Francis "Frank" J. Underwood From Netflix's House of Cards: A Textbook Case of Antisocial Personality Disorder
By Shaili Jain, MD
Posted: March 19, 2014
Posted: March 19, 2014
Category: Commentary, Psychiatry, Uncategorized | Tagged Antisocial Personality Disorder, ASPD, francis frank underwood, house of cards, Kevin Spacey, Mental Health, Psychiatry | Leave a comment


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Aerosols Companies in Georgia (US)
Category: Air & Climate ×
Subcategory: Aerosols ×
Industry: Pulp & Paper ×
Location: USA ×
Location: Georgia (US) ×
Ecotech Pty Ltd
based in Knoxfield, AUSTRALIA
Ecotech is an Australian owned company with more than 35 years experience in servicing, maintaining, designing, manufacturing, installing and commissioning ambient air and emission monitoring systems around the world. Ecotech is ISO17025 accredited for the operation and maintenance of ambient air and continuous emission monitoring systems and was first accredited in 1999. ...
based in St. Petersburg, FLORIDA (USA)
Industrial and Environmental Health and Safety Instrumentation: Air Sampling Pumps, Calibrators, Equipment, and Accessories. Colorimetric Gas Detector Tubes. Point Gas Monitors. Open Path Gas Detection. Sound, Noise, and Vibration Measurement Instruments. Real-time Dust Monitors. Flame Detectors.
Ashtead Technology Ltd
based in Letchworth, UNITED KINGDOM
Ashtead Technology was formed in 1985 when Ashtead Group plc acquired SubSpek Limited, which at the time provided underwater positioning, survey and inspection equipment rental from a base in Aberdeen. In 1994 the Singapore base was opened, focussing on the offshore oil and gas industry and the subsea telecommunications cable market in Asia Pacific. The first US ...
Thermo Scientific - Air Quality Instruments
based in Franklin, MASSACHUSETTS (USA)
The Thermo Scientific portfolio of air quality products has expanded from individual gaseous criteria pollutant analyzers to encompass a broad range of particulate monitors, toxic gas sensors, VOC analyzers and completely integrated ambient and stack monitoring systems.
ProVent, LLC
based in Harbor Springs, MICHIGAN (USA)
ProVent manufactures industrial process dust collectors with an emphasis on performance, efficiency, and longevity. The UNI-WASH wet type dust collector products have been continuously manufactured for more than 80 years and remain at the forefront of ProVent`s production today. Over 50 years of combined experience in design and application of systems assures ProVent ...
S&G Enterprises, Inc.
based in Germantown, WISCONSIN (USA)
S&G Enterprises, Inc. was incorporated in January of 1961 for the purpose of developing ideas into marketable products. We sell solutions – not just equipment. Our strength is mating the equipment with the customer's application. The original RAM FLAT Compactor was developed and sold in the 1960`s for strictly drum crushing. Additional models were later designed when ...
Catalytic Products International (CPI)
based in Lake Zurich, ILLINOIS (USA)
Catalytic Products International is the preferred resource for innovative and efficient industrial air pollution control solutions. Customers from across the globe rely on our expertise to solve their most complex VOC, NOx, and Odor pollution challenges. The custom engineered systems include, Thermal Oxidizers, Catalytic Oxidizers, Regenerative Thermal Oxidizers, Heat ...
Universal Analyzers Inc. - AMETEK, Inc
based in Carson City, NEVADA (USA)
Universal Analyzers produces gas sample extraction, transport and conditioning systems for CEM and process measurement. As part of the O'Brien family of companies we can now coordinate the interface between the sample probe, the heated sample line, the sample gas cooler and the balance of conditioning components so that all required connections are provided in a single ...


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Dr. Chinnaiyan made the discovery while studying the genetic changes in a large collection of prostate tumor samples from patients. "At the time, gene fusions were thought to occur only in blood cancers such as leukemias and lymphomas, but not in solid tumors," Dr. Chinnaiyan explained. (The best-known oncogenic fusion gene was BCR-ABL, the cause of chronic myeloid leukemia, which is the target of the drug imatinib [Gleevec].) "We were not looking for these types of genes, so the finding was serendipitous."
Today researchers believe that the TMPRSS2-ETS fusion drives the formation of many prostate cancers, but so far they have been unable to target it and block its activity. Finding small-molecule drugs to inhibit cancer growth is now an important focus of Dr. Chinnaiyan's work. He is also initiating new research projects to look for cancer-causing gene fusions in other solid tumors, including breast cancer. Dr. Chinnaiyan has been active in the wider research community as well, as co-creator of the Oncomine Research Platform, an online database containing cancer gene expression analysis information for academic researchers. He is also a board-certified pathologist and spends part of his time developing and implementing new molecular tests for the diagnosis and prognosis of cancer.
"Arul's discovery of this unique fusion in prostate cancer has opened up numerous opportunities for the development of novel diagn
|Contact: Kathleen Gibson
Memorial Sloan-Kettering Cancer Center


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Olivia Wilde Gossip
Olivia Wilde gossip, latest news, photos, and video.
Sandy to prevent another Green Lantern?
The Green Lantern was a disappointment for Ryan Reynolds. No one wants the same for his second release this summer. The Change-Up opens on Friday. And last night at the Hollywood premiere, Ryan showed up with his good friend and good luck charm Sandra Bullock in the hopes of avoiding another Lantern showing at the box office, to say nothing of the curse of Olivia Wilde. Full Story
Olivia adds to the circle
Ryan Gosling, Justin Timberlake, Jake Gyllenhaal, Bradley Cooper... now Chris Pine – word is Olivia Wilde was spotted enjoying a flirty dinner the other night in Hollywood. Page Six reports that the two looked "cozy" which... I've a feeling now that Olivia Wilde could go out with Neil Patrick Harris and someone would say they were "cozy". Full Story
Photo Assumption: Megan Fox & the Other Under 30s
Just for fun. From the Maui Film Festival. It's Megan Fox with Olivia Wilde, Andrew Garfield, and Garrett Hedlund. All of them are receiving awards at the event. I'm not sure Megan's award is acting related though... Anyway, the way I photo assume this first image it's like, well, the other three are tight, and then with Megan. Full Story
Maui under 30
The Maui Film Festival kicked off today. I know Megan Fox is scheduled to be there to pick up an award for doing right by the environment. And several other hot actors under 30 too. Is that what it's about? I hope they sent enough paps. Here are Garrett Hedlund, Kate Mara, Max Minghella, and Andrew Garfield hanging out yesterday on the island. Full Story
Olivia's next Ryan
Gosling took her to the aquarium, then it was Jakey, Justin, and Bradley? Or was it Justin first then Jakey then Bradley? I don't remember the order. But this girl is taking over from Kate Hudson's manslinger and enjoying her single summer. And since she's been linked with almost everyone so far, I suppose it's only a matter of time before they make a story about her with Ryan Reynolds. Full Story
Bradley, Zoe, and Olivia on the way
Bradley Cooper is in Montreal. He was photographed this morning with co-star Zoe Saldana rehearsing scenes for their new movie The Words. He plays a writer who steals material and has to face the revenge. Other cast members include Jeremy Irons, Dennis Quaid, Ben Barnes, John Hannah, JK Simmons and, just announced, Coop's recent hook-up Olivia Wilde. Full Story
Mystery companions
Bradley Cooper was sighted at the French Open again. He was seated next to a blonde lady. They were talking and smiling. A few of the photo agencies are all like – Bradley Cooper's with a mystery woman!!! Renee Zellweger meanwhile was photographed on Sunday in Santa Monica. She was also joined by a friend. Full Story
Bradley Cooper's big weekend in French
The Hangover Part 2, despite terrible reviews, was HUGE business at the box office this weekend. Sarah from Cinesnark will have more in depth analysis on the numbers tomorrow. For now, in short, where Bradley Cooper is concerned, that's two for two. Full Story
Ryan, Jake, Justin, Bradley…
Olivia Wilde announced her divorce in February. She's 26 and had been married 8 years. So I guess I don't blame her for going kinda boy crazy. I mean she looks great, she's connected, as long as she's not, like, begging people to stay with her, to love her, to Biel her, it's hard to argue with the girl's single summer strategy. Full Story
JT, Gaga, & all his girls Pt 2
There were three of them floating around New York this weekend, surrounding him, swelling his head, the Big Man. Page Six reports that at the SNL afterparty, Pips was supported by "friends' Olivia Wilde AND Mila Kunis. Both have been linked to him, and both happened to leave around the same time he did. Full Story
Olivia Wilde has really goodlooking friends
First it was an aquarium date with Ryan Gosling. Click here for a refresher. Then she and Justin Timberlake were supposedly hooking up at a club. Click here if you missed that. She subsequently denied it. Full Story
Jakey's many dates
Us Magazine says that Jake Gyllenhaal had breakfast with Jessica Lowndes in New York last Friday. Curiously that's the same day that Taylor Swift and Garrett Hedlund had dinner for the first time in Tennessee. Click here Full Story
Pippy > Ryan Gosling?
It's a Mickey Mouse Club love triangle…ish. Olivia Wilde was last seen with Ryan Gosling on a lame date at the aquarium. Sounds like she prefers The Roxbury. The Roxbury??? Justin Timberlake goes to The Roxbury? On Saturday night, yes. And conveniently People.com Full Story
Making a bag of dogsh-t look good
It's not my favourite thing in the world, picking up my dogs' sh-t, but it's what happens when you have dogs. You pick up a lot of sh-t. And here's Ryan Gosling after picking up his dog's sh-t in Detroit on the set of the Ides of March. I like it that Ralph has been travelling with him. Full Story


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An astonishing historical novel in the tradition of Schindler's List--evoking powerfully the danger and heroism of the Nazi resistance. What is the price of acting morally in a time of great evil, when sin and necessity seem twinned? Saints and Villains is a strikingly resonant novel that dramatizes this painful dilemma through the fictional re-creation of the life of Dietrich Bonhoeffer. This emblematic figure risked his life--and finally lost it--through his participation… (mehr)
Verlag: W. W. Norton & Company (25. Oktober 2010)
Format: EPUB
Dateigröße: 740 KB
Schutz: DRM
Sprache: Englisch


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