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December 5, 2012
The National Endowment for the Humanities has awarded NYU's Center for European and Mediterranean Studies (CEMS) a grant of $86,611 to run a summer seminar, "Eastern Europe in European History," to provide background on the subject for K-12 teachers and graduate students who plan on entering the field of education.
Larry Wolff, director of CEMS and a professor in the Department of History, will direct the seminar, which will run the first three weeks of July 2013.
Seminar content will address modern European history, from the 18th century to the present, focusing on the ways in which Eastern Europe is often left out of conventional presentations and narratives, while exploring the ways in which Eastern Europe might better be included, both intellectually and pedagogically. The purpose of the seminar will thus be to arrive at a more comprehensive conception of European history, East and West. It aims to offer a portrait that reflects today's Europe, with the expanded European Union of 27 countries, rather than the divided Europe of the Cold War period when Western Europe was always assumed to have priority over Eastern Europe—both in contemporary politics and in European history. Among planned topics for class sessions are "The 19th Century: East and West in the Age of Nationalism"; "Woodrow Wilson and the Paris Peace Conference"; "Communism and Eastern Europe"; and "Europe after the Cold War and EU Enlargement."
The seminar will also include guest lectures by Stefanos Geroulanos, an assistant professor in the Department of History ("20th-Century European Intellectual History, East and West"), Michael Beckerman, Carroll and Milton Petrie Professor of Music and chair of the Department of Music (Czech music), and Emily Greble, an assistant professor of history at the City College of New York (the city of Sarajevo).
For more information, go to: http://cems.as.nyu.edu/page/neh2013.
This Article is in the following Topics:
NYUToday-feature, Arts and Science, Research, Faculty
Type: Article


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If you haven't noticed, we've been busily posting memes to Facebook as a tribute to the gazillions of faithful Bookooers who declutter month after month, year after year, in pursuit of organizational perfection.
For those of you that haven't quite achieved that coveted empty garage, you're in good company—with us! It's a process. We get it. ;-)
Thanks to Brittany at PrettyHandyGirl.com and Kathy McEldowney for allowing us to use their awesome photos!

subset: commoncrawl


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Integration on an orientable differentiable n-manifold is defined using a partition of unity and a global nowhere vanishing n-form called volume form. If the manifold is not orientable, no such form exists and the concept of a density is introduced, with which we can integrate both on orientable and non-orientable manifolds. My question is: On a non-orientable n-manifold, every n-form vanishes somewhere, but shouldn't I be able to chose an n-form with say a countable number of zeros, which would then constitute a set of measure zero and thus allow me to use n-forms (with zeros) for global integration also on non-orientable n-manifolds?
The problem is that there is no way to figure out signs - It would be like trying to integrate a function from $\mathbb{R}$ to $\mathbb{R}$ without knowing whether you were moving forward or backward.
What you CAN actually integrate are pseudo-differential forms. The whole point of choosing an orientation is to turn a differential form into a psuedo-differential form. For those, I recommend the wonderful short story by John Baez found here:
This is not an answer, but on reading the discussion I thought that it would be nice if someone gave the definition of a density so that no one would think that it is a complicated object. I learned the following (somewhat more general definition) from I.M. Gelfand:
A $k$-density on a manifold $M$ is a continuous real-valued function defined on the
cone of simple (a.k.a. decomposable) tangent $k$-vectors on $M$ that is homogeneous of degree one. A $k$-density $\varphi$ is said to be smooth if for every $k$-tuple of smooth linearly independent vector fields $X_i$ $(1 \leq i \leq k)$ defined in some open set $U \subset M$, we have that the function
y \mapsto \varphi(X_1(y)\wedge \cdots \wedge X_k(y))
A densitiy is called even if $\varphi(-v) = \varphi(v)$ for every simple tangent $k$-vector $v$. Likewise, we have odd $k$-densities that generalize differential $k$-forms
Examples and context
If $\Omega$ is a volume form on a manifold of dimension $n$, then both $\Omega$ and $|\Omega|$ are $n$-densities. The arc-length element of a Riemannian or Finsler metric is a $1$-density. The $k$-area integrand of a Riemannian or Finsler manifold is a $k$-density.
Parametric integrands (in the sense of Federer-Fleming) define $k$-densities when restricted to the cone of simple vectors, but densities are way more general.
Varifolds of dimension $k$ are elements of the dual to the space of even $k$-densities. This is basically their definition: because of their homogeneity even $k$-densities can be seen as continuous functions on the bundle of tangent $k$-planes.
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For more examples and for neat applications to integral geometry (if I may say so myself ...), which becomes much easier if differential forms are replaced by densities, see the paper Gelfand transforms and Crofton formulas.
First of all, the things that you actually integrate are densities, which are the differential geometric counterparts of measures. No orientation is needed.
A degree $n$ form on an $n$-dimensional manifold is almost a density, but not quite. We need an orientation to associate to the top degree form a density. This is what you ultimately integrate when you integrate a form. For more details see page 105 of these notes.
You would expect the zero set of an $n$-form to have codimension 1 rather than being countable. Your suggestion of choosing some $n$-form on a non-orientable manifold $M^n$ and defining integrals relative to that essentially amounts to cutting $M$ into two orientable pieces along a codimension 1 submanifold, choosing an orientation on each, and adding the integrals on the two pieces. You can certainly do that, but since the answer depends on the choice of $n$-form/cutting it is not very natural or interesting (whereas the integral on an oriented manifold only depends on the orientation and not on the choice of orientation form).
I think one reason that integration of forms instead of densities is prefered is that one can use Stokes theorems.


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6 Studies That Prove Reality TV Is Causing the Apocalypse
#3. There Is More Reality TV Than Science (And We) Can Handle
"Determining Dimensions of Reality: A Concept Mapping of the Reality TV Landscape"
Robin L. Nabi, Professor, U. Penn.
Journal of Broadcasting & Electronic Media, June 2007
That title might sound like something Reed Richards would shout before accidentally opening a portal to hell in downtown Manhattan, but it's even worse: There are now so many reality shows that researchers are trying to map them. Like an oceanic trench, but with even more horrific abominations in it.
Science confirms that the giant isopod is a more medically advisable sexual partner than any Bachelor ever.
There are now so many reality shows that a scientist had to apply multidimensional scaling to map them, though she may lose that job title because of it. A study of 300 locals found that the only two themes they all agreed on were "romance" and "competitiveness," making Pennsylvania possibly the worst place for dating or small talk in the entire world.
They prove their scaling works because they realize that Newlyweds and Wedding Story -- shows about people who decide to sell their own marriages for fame -- are measurably less romantic than Punk'd.
Professor Nabi concluded with concerns about how viewers were being reprogrammed with romance and competition as their two main drives. "Repeated pairing of these two attributes might create and/or reinforce the view of potential mates as prizes to be won rather than cherished long-term relational partners." Reality TV actively ruins romance for the next generation by turning it into an ugly fight.
Thanks, science. We hadn't worked that one out.
#2. It Even Manages to Make the Internet Dumber
"Reality Television as a Model for Online Behavior: Blogging, Photo, and Video Sharing"
Professor Michael A. Stefanone, Ph.D., Derek Lackaff
State University of New York
Journal of Computer-Mediated Communication 14, p964, 2009
A study at the State University of New York linked reality TV with the need to share every pointless detail of your life online and accelerated the downfall of human intelligence by giving 100 students class credits for talking about reality TV. That's the exact opposite of what universities are for. Professor Michael Stefanone found a significant association between the quantity of RTV consumed and the decision to maintain a blog full of "nondirected self-disclosure," the most scientific-sounding way to describe talking about what you had for lunch.
"How did people tell strangers about their sex lives before the Internet?"
Growing up with reality television teaches you that sharing every irrelevant thought as publicly as possible isn't the province of lunatics in trench-coats and attention whores but is "normative" and "prosocial," which we're fairly sure are psychobabble words for good things. Keeping Up With the Kardashians being taken as the basis of a society makes 1984 look like a nice future. Hell, it makes Fallout 3 look good.
We'd prefer global nuclear war to the invention of the spray-on tan.
It's a cargo cult: They see people with absolutely no ability becoming famous, sharing absolutely every irrelevant detail of their lives with the world, and confuse one of the effects with the cause. They then proceed to pour out every pointless emotion in a never-ending toxic spill of weaponized boredom.
#1. The One Way Reality TV Seems to Be Useful
"Organizing Customers: Learning From Big Brother"
Professor Tobias Fredberg
Chalmers University of Technology
Long Range Planning 42 (2009), 320-340
So the arts and sciences used statistical analysis, mathematical modeling and freaking Aristotle to take a long, hard look at reality TV and were at best confused and at worst, found themselves looking into the inky black eyes of a murder bot in the moments before they roll over white and begin to attack. But surely all our viewing behaviors are telling someone something useful.
The title 'Organizing Customers: Learning From Big Brother" combines more horror and blatant exploitation than Shaft filming a Saw sequel. It couldn't imply the viewers were sheep harder if it somehow suggested they be ground up for mutton. That would still be more respectful, because even farmers don't use the phrase "and hence enable extraction of value." Which isn't just a quote from the paper, but the stated goal of the paper from the intro.
The paper reads like it was written by Terminators. If you replaced every incidence of "customers" with "toasters," there would be more human emotion because it would at least be surprising to read that toasters had money. But there is nothing surprising about this analysis of fan behavior. At least not to anyone who was paying attention to every cartoonishly evil businessman to ever kill the good guy without a trace of remorse, or any of Bill Hicks' observations about advertisers.
He once ate a marketing director's heart.
Beyond their capacity for spending money, there is literally no way to detect that the researchers are talking about living beings. For instance, the abstract notes that, "As their commitment grows, they become prepared to spend more to access new streams of Big Brother information." You only need to look at the fact that people are now buying seasons of reality shows on DVD to see that TV executives have learned from Big Brother's ability to get us to spend.
We're fairly certain watching any episode on this DVD more than once qualifies as a severe mental disorder.
But is it just a fad? Well, things keep happening if they make money. And reality TV is making a lot of money, thanks to the fact that a real TV show costs over a million dollars to make, while a reality show costs around $100,000. They're so cheap that many of the people winning the cash prizes could fund their very own shows. A Survivor winner could produce an entire six-episode series. And when that happens, future readers, it should be taken as the signal to climb into your Repulsor Armor and begin Operation: Purge. Don't worry -- your targets will all be held motionless for at least 30 minutes.
Be sure to pick up our book since we're guessing you probably shot your TV after reading that.
For more reasons to huck your television out of a window, check out 5 Ways Television Went Crazy Since I Quit Watching in 2003 and 6 Deadly Injuries You Think You'd Survive (Thanks to Movies).


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- Color
- Fair/Light
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Try pairing with High Definition Healthy FX Foundation for a flawless complexion.
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from washington, dc
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I have a triangle $ABC$ with side lengths $a,b,c$ (edges $BC, CA, AB$ respectively).
I have a point $p$ with barycentric coordinates $u:v:w$.
These are normalised: $u+v+w=1$. $1:0:0$ corresponds to point $A$, $0:1:0$ is $B$ etc.
Is there a simple expression for the distance $d$ of the point $p$ from $A$ ?
(My initial naive guess based on $d(1:0:0)=0, d(0:1:0)=b, d(0:0:1)=c$ was that $d$ was linear $d(u,v,w)=v*b+w*c$ but this is clearly wrong as in the case of an equilateral triangle $a=b=c=1$ it returns $d=2/3$ for the centroid ($u:v:w = 1/3:1/3:1/3$), when the correct answer should be $1/\sqrt 3$ (the radius of the circumscribed circle)).


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ANDERSON, S.C. – After coming off a 28-27 tiebreaker win over regional opponent King last Saturday, Anderson University wrestling returns to action for the highly anticipated Super Region 2 Duals on Saturday at Newberry's Eleazer Arena.
Anderson will be joined by nine other participants at this year's duals as Belmont Abbey, Coker, Findlay, Indianapolis, King, Limestone, Shippensburg and Tiffin will join host Newberry, to round out this season's field. Saturday will mark the first time in the program's history AU will compete in Region 2 after competing in the East Region, which is now Region I, for several years. Last season, the Trojans picked up a win over Seton Hill in their final match in the East Region Duals.
Sophomore Zak Hale looks to continue leading the Trojans this season after being ranked fourth regionally by the Basford Rankings, which were released on Thursday. Hale is 12-3 on the season as he leads the team in wins and pins on the season.
Joining Hale in the middle of the AU lineup is junior Sean Turner (149) and Zane Newton (157). Turner, who had a six-bout winning streak snapped at Belmont Abbey, bounced back with a first period pin over King's Frank Yattoni to improve to 7-2 on the season. With the setback at BAC, Turner dropped out of the top-8 in the Basford regional rankings.
Newton enters the weekend with the second most wins on the team, holding an 11-5 record. Newton has claimed three wins in his last four bouts, as nine of Newton's 11 wins have come by decision.
The Black and Gold begin Saturday with a meeting against Findlay in Session I beginning at 9 a.m. The Roughnecks, who enter the weekend with a 1-6 dual record, are coming off an 0-3 run at the 2014 Ranger Duals in Kenosha, Wis. last Saturday.
Headlining the Roughneck lineup is Adam Walters, who is currently ranked No. 2 nationally at 174. Individually, Walters finished 3-0 at the Ranger Duals, highlighted by two victories by fall. Walters came into the 2013-14 season with All-American status at the 2013 NCAA Division II Championships, finishing fourth at 184.
Anderson continues its schedule at 10:30 a.m. when it takes on Shippensburg. The Raiders come into the weekend with an even 6-6 record in duals this season, but winners of four of their last six. Last weekend, Shippensburg went 2-2 at the Mid-Penn Duals in Millersville, Pa., as the Raiders grabbed wins over Stevens Tech (37-10) and Sacred Heart (27-21).
Two Raiders posted three victories on the day, as Kyle Barnes went 3-0 at 149, while Evan Ramos finished 3-1 at 184 and 197. With the victories, Barnes improved to 8-3 on the year, while Ramos moved to 16-6.
AU's third dual of the afternoon is scheduled to be against Tiffin at 1:30 p.m. The Dragons are currently 2-8, as they recently dropped a matchup to nationally ranked Pittsburgh-Johnstown 42-6. A mixture of attached and unattached wrestlers for Tiffin took part in the Purple Raider Open hosted by Mount Union last Sunday as sophomore Chris Baker and Sam Viengmany both found spots on the podium.
In their final dual, the Trojans will square off against nationally ranked Indianapolis at 3 p.m. UIndy currently holds a 5-6 record this season, as it finished 1-1 at the Ranger Duals with a win over Wisconsin-Parkside (24-18), and a setback to Augustana (38-9). The Greyhounds are scheduled to compete in six duals on the day with AU being their fifth.
Indianapolis is currently ranked No. 10 nationally as it is led by senior Cameryn Brady who is 21-1 on the year at 149. The Lowell, Ind. native was slotted fifth nationally and first in the region in the latest Basford Rankings released on Thursday. Brady is joined by Justin Kieffer (7th – 141) and Alex Johns (5th – 125) who were slotted in the national poll.
The road trip to Newberry will end a grueling road stretch as the Trojans will host their first dual of the season on Jan. 30 when they welcome Coker to the Abney Athletic Center. The first bout is set for 7 p.m.


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MATLAB and Simulink resources for Arduino, LEGO, and Raspberry Pi testLearn more
Opportunities for recent engineering grads.Apply Today
New to MATLAB?Learn MATLAB today!
This solution is locked. To view this solution, you need to provide a solution of the same size or smaller.
%% x = 'But I''m actually right this time'; y_correct = 'yes'; assert(isequal(wiferight(x),y_correct))
%% x = 'But you just said that 2+2=3'; y_correct = 'yes'; assert(isequal(wiferight(x),y_correct))


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I have Ubuntu 12.04 and Windows7 installed onto a machine so that I could boot into either one. I wanted to keep using the Windows bootloader (actually EasyBCD), so I made sure that I didn't install Grub into the MBR, and all was well.
However, a week or two ago, just doing a routine update with Update Manager, it updated Grub but put it into the MBR (without telling me and without asking my permission), disabling the Windows bootloader, so now the machine boots into Grub instead. I'd like to get it back to booting into the Windows bootloader.
I've read it is easy to fix this, but I don't know how. Any help?


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The purpose of this guidance is to help NYU investigators meet the regulatory requirements involved with conducting human subject research with other institutions located within the United States, as well as entities located outside of US territories.
NYU investigators who work with other institutions must fulfill requirements that may vary depending on the following factors:
With these issues in mind, some general principles to be aware of when seeking approval to conduct human research with other institutions include the following:
If an institution is engaged in human subjects research that is conducted or supported by any agency of the U.S. Department of Health and Human Services (HHS), the institution must have assurance of compliance with the HHS regulations (45 CFR 46.103) for the protection of human subjects. Assurance of compliance and federal oversight are managed by the Office for Human Research Protections (OHRP) under the provisions of the Federalwide Assurance (FWA) program. Links to additional information are provided below:
Obtaining an approved assurance from OHRP: Obtaining assurance is a two-step process:
NYU IRB policies and procedures for working with other institutions are consistent with guidance set forth by the Office of Human Research Protection (OHRP) and encompass ethical principles accepted internationally.


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Home › Scene › Networking Night ›
Networking Night
THE PARTY Former Wall Street businesswoman Alison Levine headlined a networking event hosted by The Network of The Jewish Federation of Greater Washington, an organization dedicated to strengthening Jewish identity in DC and around the world. THE PEOPLE More than 400 local government officials, business leaders and executives mingled at the Ronald Reagan Building for Washington's largest Jewish networking event. BEST IN SHOW Levine delivered an uplifting speech about how she defied the odds under the most strenuous circumstances to become an elite businesswoman and explorer. Photography by Bob Stevens


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I am a university student. Of late, I have gotten into the habit of 'studying' at the last moment. Before I proceed, let me clarify. In my university, exams have questions that require me to write lengthy answers; we do not have multiple-choice questions.
Now, my strategy is that I like to delve into the topic that is being taught, learn about it, make notes but not memorize them until the last moment. I know that I do not remember the exact words for more than a couple of days after the exam but I am sure that the topic sticks in the back of my head.
Like Einstein suggested, I can explain these topics to a four-year-old.
The question that remains is : is this the "right" approach ? Are there any techniques for managing situations like these ?


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As new Morehouse Parish Schools superintendent Dr. George Noflin prepared for the administrators' two-day retreat that ended Friday, he knew there was one unresolved task that needed addressing.
"I knew relationships needed to be established. They needed to get to know me, without the tie on," said Noflin, who was hired in April, about his co-workers.
Read the full story in Saturday's print edition of the Enterprise.
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Cleanup bucks welcome in city
Waterbury grabbed a dose of luck this month with the notice that $2 million is forthcoming to scrub the burned, contaminated Nova Dye and Print Corp. factory in the South End. The money from the state Department of Economic and Community Development will enable the city to prepare the potentially valuable site for redevelopment.
Officials were not quite so optimistic after the former textile mill went up in flames in April 2012. Like many other abandoned factories in the Brass City, it was unclear who owned the site and might be obligated to fund the cleanup. City officials identified the last group of owners, but it seemed unlikely they could be held to account. "Naturally, taxpayers will be stuck with what could be a monstrous bill for demolition and cleanup," the Republican-American said in an April 17, 2012 editorial.
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Burgettstown wins operner
CANONSBURG, Pa. - Behind 22 points and nine rebounds from Ryan Glover and eight points and 15 boards from Josh Mack, the Burgettstown boys basketball team won its season opener, 67-57, over Waynesburg Friday at the EQT Energy Classic Tipoff Tournament at Canon-McMillan High School.
The Blue Devils led 17-6 after eight minutes and put the game out of reach by outscoring Waynesburg 19-11 in the third quarter for a 48-30 lead.
Logan Triebsch and Jonathan Sabo added 10 points each for Burgettstown.
Spartans fall to Blue
WHEELING - The St. Joseph Spartans JV boys dropped a 34-17 decision to St. Mike's Blue in Wheeling Parochial League play. The Spartans were paced by Robbie Valenti's eight points. St. Mike's Jack Wilkinson led all scorers with 14 points.
Dunnom arrested on murder charges
WEST LIBERTY - A West Liberty football player has been arrested on charges related to a slaying in Florida.
Deputy U.S. Marshal Chad Simpson in Wheeling says 24-year-old Vernon Dunnom was arraigned in Ohio County Magistrate Court on Friday on charges of first-degree homicide, attempted homicide and two counts of robbery.
Simpson says two people were shot, one fatally, during the robbery Nov. 17 in Miami Gardens, Fla. A warrant for Dunnom's arrest was issued out of Miami-Dade County.
Dunnom is being held at the Northern Regional Jail in Moundsville pending an extradition hearing. Jail records didn't indicate whether Dunnom had an attorney.
Dunnom is a junior defensive end and running back from Pittsburg, Calif. He appeared in four games for West Liberty this season.


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Please suggest to me the lightest Debian Linux release with console only (no GUI). Please don't suggest any net install like
netinst. I need an ISO of that release which is capable to boot and install from.
Later I'll install my own chosen GUI and applications for my needs from Debian/Ubuntu repositories.


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University Elections
The University encourages staff and students to participate in elections for boards and committees where they are eligible to stand as candidates or to vote.
Staff and student participation in decision making bodies is an important part of University life and provides valuable professional development and learning experiences.
Elections are conducted in accordance with University regulation 7.1(1) - Elections and the Elections procedure for:
Faculty elections are conducted by Faculties:
If you have any questions or comments please email us.
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If you think @_Diana_PS would enjoy Favstar, please invite them to take a look, and perhaps unprotect their account so they can join in the fun.
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One piece bathing suit w/ zipper front for $59.99 + free shipping
Made in the USA! Designer black one piece bathing suit with plunging neckline accented with a white zipper. Classy and daring, this will attract attention!
3 Comments add a comment
Err... Dad??? xD
Plunging neckline? I think that is an understatement.


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Google Chrome  23.0.1271.91
(Open Source)
Change Log
* Fixes several issues including:
- No audio from Flash content when speaker configuration is set to Quadraphonic
- Aw, Snap renderer crash on Windows Server 2003
* Security fixes
- Corrupt rendering in the Apple OSX driver for Intel GPUs.
- Use-after-free in SVG filters.
- Out-of-bounds read in Skia.
- Browser crash with chunked encoding.
- Buffer underflow in libxml.
- Use-after-free with printing.
- Bad cast in input element handling.


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Shirts are necessary for service in most restaurants in the United States, but not Canada. Covering the most vital parts of your body, shirts are great for any occasion.
We've got some great picks from our latest inventory for you!
Jeans, Slacks, Trousers, Breeches, Chaps, whatever you call them. They keep stuff off your legs and I think that is pretty cool. So personally an endorsement for pants? Yes.
Check out our latest favorites from the world of pants!
Whether your looking to impress the new boss, or show off your best for that special someone, special occasions demand a special suit. Also <3 penguins obviously, they've really got it figured.
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I'm in with the outerwear. I'm cool with the cats. I'm toasty in the frosty with my fresh new jacket. Winter is coming son wut wut!
Here are some of our favorites for very chill times.
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Does Sunscreen Expire?
Last Modified: August 13, 2012
Does sunscreen really expire? If so, how do I know how long it is good for?
Rachel Woods, RN, Nurse for the Surgical Dermatology Program at Penn Medicine responds:
Sunscreen does have an expiration date imprinted somewhere on the bottle. It is usually good for about a year.
This question and answer was part of the OncoLink Brown Bag Chat Series. View the entire Sun Safety Webchat transcript.


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Dylan Hampers
Vintage style hampers for kids. Set of 2 metal kids' hampers. Mesh hampers with wood handles. Your choice of white or silver. Set includes one each: Large: 19"D x 1918"H and Small: 17 1/2"D x 16"H. Imported. Keep laundry and towels neat and organized with our metal mesh hampers for kids. The super-convenient sizes of our Dylan kids' hampers are perfect for a child's bedroom or a bathroom. Kids' hampers are a great way to encourage children of all ages to toss their dirty clothes into the laundry – not on the floor! Dual wooden handles make the hampers easy to carry, so you can take them to the laundry room or from room to room. Convenient set includes two sizes of hampers: larger is 19"D x 19"H and smaller is 17 1/2"D x 16 16"H.
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$527,199WHAT: The estimated cost for the city of Newton's proposed bike path extension. The project consists of the construction of a 10-feet wide, 5-inches thick, 6,500 foot long concrete pathway.WHERE: The path will follow along the west side of Spencer and the north side of Southeast 36th, connecting to the bridge over I-135. The pathway will be marked as a bike path facility that is shared with pedestrians.WHEN: The project is proposed for 2019.WHY: The city's capital plan states extending the pathway provides for a separation of bicycle and pedestrian traffic from industrial vehicle traffic along Spencer. The pathway also could tie into a future YMCA or other recreational facility in the future.HOW: City staff said they plan to pursue grant opportunities when available for funding.Have a question about a local government budget? Contact us via email at email@example.com, Attn: Budget breakdown, or call us at 283-1500.
Location, ST | website.com


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Rear Disc Brakes - All Bound UpWritten by on June 18, 2012 Better Binders out Back in a Day
When it comes to discussing the history of Mopar, the first thing that everyone remembers and talks about is the fact that Mopar knew how to go quick and win races. The cars were often in the winner's circle, and were unsurpassed in their ability to accelerate. But, what no one seems to remember is the sometimes less-than-adequate braking capabilities of these cars. Sure, in stock form, a '70 Road Runner was aptly capable of stopping while driving through town--in 1970, but in today's traffic...
There are a lot of reasons you should consider when it comes to upgrading to disc brakes. The main reason is safety. For starters, drum brakes are easily damaged by heat and moisture. Get them wet or hot, and they will not work--period. Even when they're in good working order, they offer less-than-optimal stopping power, especially in today's traffic conditions. Chrysler actually introduced standard disc brakes on the front of their vehicles sometime in the 1950s, but it wasn't until the mid-1960s, when power-assisted units, which made disc brakes easier to operate, hit the market. Some modern vehicles still come with drum brakes on rear wheels. Rear drum brakes are cheaper to produce than disc brakes, and since a vehicle's front brakes actually do 70 percent of the work, rear brake performance can be sacrificed for cost.
Since drum brakes do have their limiting factors, and adding front disc brakes to your car is definitely an upgrade in safety and performance, is an upgrade to rear disc brakes worth doing on your car? This is a question that only you can answer for yourself. Some guys feel that rear drum brakes are more than sufficient for stopping their cars, and it's true that a good working drum brake system on the rear of a car can work properly during normal driving conditions--if you have front disc brakes. If you have drum brakes on all four corners, just think back to the last time you panic-braked when some idiot pulled out in front of you, and tell me that an upgrade isn't worth it.
It goes without saying that you can't install rear disc brakes on your car if the front has drums on it. Well, you could but when you hit the brakes, your rear tires will lock up before the front ones even start to slow down. But if a car equipped with front disc brakes and rear drum brakes is sufficient, why upgrade to rear disc brakes? For starters, the front discs can only do so much. Have you ever noticed that your rear drum shoes last much longer than the front shoes/pads? We've been told that by adding rear disc brakes to your car, you can effectively add as much as 30 percent more braking force to your braking system. This means you stop a lot quicker, which could come in handy when that idiot pulls out in front of you.
But, you might be worried that adding a rear disc-brake kit to your car is going to be too expensive, and granted, you will have to shell out a few hundred dollars for a kit that works on your car. But, how much would the bodywork be if you actually ran into the aforementioned idiot?
We've had a couple of close calls in our Dart Sport, and it scared us enough to convince us to do some research about what's available in regards to a rear disc-brake kit. But like you, we were more than a little concerned with what these kits cost. Let's face it, there are a lot of kits out there, and depending on the options you choose, it can get pricey really fast. We actually stumbled across Master Power Brakes' website during our research, and were pleasantly surprised to find a basic rear kit for our Sport that wasn't as expensive as a lot of other kits. The kit from Master Power Brakes included 11-1/8-inch multi-pattern vented rotors (this means you can use them with either 4-inch or 4-1/2-inch bolt pattern wheels), single-piston calipers with pads and integral parking brake, the required brackets, hoses, and cables. It was a complete kit for a fair and economical price. But, if we installed them, would we see a significant improvement in braking distance. The only way to find out was to order the kit and put it to the test. Before we started the install, we took our car to the local industrial-park-straight-stretch-of-road-testing facility after 5:00 pm, and set up a test. We decided that we would get the Sport up to a speed of 60 mph, and when we got to a marked spot on the road where we would start our measuring, we would hit the brakes and see what happened. With our rear drum brakes, the Sport managed a stopping distance of 133 feet and 6 inches. Apparently that was fairly close to where everyone thought it should be, but what would happen when we installed the rear disc brake kit? For those results, you'll have to check out the end of our article.
According to the guys at MP Brakes, if your vehicle was originally equipped with disc/drum brakes, it would have come from the factory with a combination valve that includes an internal metering valve. Metering valve delays the pressure sent to the front calipers, because the springs in the rear drums do not allow the shoes to engage as quickly. This "delay" allows the shoes in the rear drums to engage slightly before the front calipers, thus reducing nose dive. For a disc/disc system, you do not want to use a metering valve. If your car has a combination valve with an internal metering valve, the combination valve should either be replaced with one that does not include a metering valve, or the metering valve could be removed and the opening plugged with a correct size plug.
Editor's note: To remove the metering valve, first remove the cap and plug at the end of the combination valve. After that, simply remove the metering valve, and then reinstall the plug and Loctite it in place.
Location, Location, Location
There are different theories, rumors, or just outright guesses when it comes to the actual position of the caliper in relationship to the rotor. We've heard guys say that the brakes work better with the caliper behind the center line of the rotor. Some say it's better if in front of the center line. And yet others say it doesn't matter. We have even seen situations where the calipers are positioned at the very bottom location of the brake discs. The thinking there is that by binding the lowest point possible on the rotor, you are also creating the lowest possible center of gravity for the wheels. The calipers used on the MP kit are sourced from GM, and the design of these calipers is to mount them aft of the axles. This allows the parking brake cables to feed in from the front. According to our contact at MP Brakes, "We suspect the choice of location [from the OE], was chosen more for packaging than anything. Locating both front and rear calipers to the inside (behind the spindles on the front and in front of the rear axles on the rear) would provide a slightly lower center of gravity, and there might also be a slight advantage in the polar moment of inertia, but any difference would be so slight that we doubt any difference could be noticed, especially on a street car."
Terms You Need To Know
Single-Piston Caliper Single-piston calipers have been the standard in braking for years. Single-piston calipers are very simple, and perform well in most applications. With the single-piston design, the disc brake rotor is squeezed between a pad that is stationary on one side, and a pad that is moved by the caliper's piston on its other side. The advantage of this design is that it's very simple, and is not prone to leaking or failure.
Four-Piston Caliper The four-piston caliper was the original design used by Chrysler. This system had one major weakness--four-caliper pistons had four times the chance of leaking or failing since there were four of them. Long term function without failure was the driving force to go to the single piston caliper design. An advantage of newer designed four-piston calipers is that the caliper is less prone to flexing under stress as opposed to early designs, which keeps the pads more evenly pressed on the rotor, producing more friction and stopping power. With today's four-piston calipers, the leaking problem can be virtually eliminated or severely reduced by having the caliper's piston bores sleeved with stainless steel. This eliminates bore corrosion, which leads to leaking.
Rotor Size Efficient braking requires the conversion of your car's kinetic energy into heat. This heat is produced by the rotor being clamped between the disc brake pads. Fast dissipation of this heat is critical to achieving good brake function. In essence, the larger the rotor, the more efficiently it will dissipate heat, which translates into better braking. For most street applications, an 11-inch rotor is more than sufficient.
Vented Rotors Vented rotors are essentially two parallel discs with airspace between them. Between the two discs are air-moving fins that hold the two discs together. The function of these fins is to increase the speed in the rotor cools.
Cross-Drilled Rotors Better braking performance is all about cooling the rotor as fast as possible. When a rotor is cross-drilled, these holes help to discharge the heat and gases that build up within the rotor, and therefore cools it faster and clamps better. We need to make note that some guys feel that cross-drilling a rotor does increase its tendency to develop heat cracks that develop from the drilled holes.
Slotted Rotors When friction is produced by the clamping of the caliper, a gas is also emitted along with heat from the pads. The theory is, these slots help remove the gases that develop under the pads. Although cross-drilled and slotted rotors are not an absolute necessity for street use they are a relatively inexpensive upgrade when adding disc brakes.
|Brake Kit
|Metal Brake Line Tubing
|Brake Fluid
|We Already Had Some
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1 We're sure you guys know how to remove the existing drum brakes, and Master Power includes instructions with their kits, so we'll focus on the install. With the drum brakes and axles removed, it's time to start putting it back together. First, install the spacers. The spacers are needed to replace the thickness area lost by removing the brake's backing plate.2a With the spacer, the axle, and the lower caliper bracket in place, you can see that the factory t-bolts that held the backing plate in place are now too short.2b MP supplies new, longer bolts and nylon-insert nuts, so don't leave the factory ones in place.4 The calipers used on the MP Brakes kit are a floating, pin-mounted style. A floating caliper (also called a sliding caliper) is able to move/float with the rotor. When applying the brakes, a piston on one side of the rotor pushes the inner brake pad until it makes contact with the braking surface, and then pulls the caliper body with the outer brake pad so pressure is applied to both sides of the rotor. If they were a fixed caliper, the caliper would not move/float, which makes them less tolerant of rotor imperfections. It also uses opposing pistons to clamp from each side of the rotor, and is more complex and expensive than a floating caliper.5a The kit comes with the rubber brake lines that you'll need to go from the caliper to your supplied hard line.5b Master Power also supplies the bracket that attaches to the axle tube for mounting the hose. You can weld yours fast, but we chose to use a stainless hose clamp.6 A complete cable set for the emergency brake system is also supplied. With the MP Brakes rear calipers, you must connect the emergency brake cable so it functions. These calipers use the emergency brake cable as the adjuster for the brake adjustment on each caliper. If the E-brake is not applied when the car is parked, your brakes will get out of adjustment and will eventually not work.
8 You will also need to install the new main E-brake cable. This is a supplied, universal cable and requires cutting to fit. Before you cut it, back the E-brake tension adjuster off, so you can have the full range of adjustment after its put back together with the new cable.9a Once completely installed, the fluid system bled, and then carefully tested in the shop parking lot, it was time for some actual hard brake-testing. With the new rear disk brakes, we cut our braking distance down to 122 feet and 4 inches.


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Enfield Rehabilitation and Health Care Center is opening up their monthly Pancake Breakfast to everyone. The breakfast is held on the first Friday of each month at their facility, located at 408 N. Wilson Street in Enfield.
The breakfast is available to guests from 7 until 9 a.m.
For more information, call (618) 963-2331.
Location, ST | website.com


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Is there a .NET library to calculate area enclosed by polygon made up of geo coordinates (lat longs)?
SharpMap has a polygon class with an Area method. But before calling that, you should consider projecting the polygon's coordinates into an equal area projection to yield meaningful results. It looks like SharpMap uses ProjNet, which has Albers, but I also see there is now a c# wrapper for Proj4.
NetTopologySuite offer what you need, and much more: http://code.google.com/p/nettopologysuite/
Another option is using the Microsoft.SqlServer.Types library. While it isn't supplied in .NET, it is available as a nuget package, or you can find it in your SqlServer (or Express) installation (%programfiles%\Microsoft SQL Server\100\SDK\Assemblies) as Microsoft.SqlServer.Types.dll
Obviously, it relies on Microsoft (and the SQL types library which could have it's own licencing issues), so the other options supplied may well be better options, but if you are already integrating with SqlServer 2008, then this may be a nice way to go.
To do an area calculation is pretty simple (I have included an NUnit test below demonstrating it.
Link to System.Data.Entity.dll and use the DbGeography object such as:


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Hi All,
Totally new to this forum. Thanks in advance.
I am looking for second hand gear for the G trusted photographer course.
I need the Nodal Ninja Ultimate R10 with compact 90º rotator & Sigma 8mm f3.5 EX DG.
It must be for a Canon. Anyone, suggestions, pointers would be greatly appreciated.
Have a great Easter everyone.
BTW, I am in Spain.
Regards, Canucki


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STEUBENVILLE -Carla Bezak started crying when retired Secret Service Agent Clint Hill began to recite the details about the final hours of the life of President John F. Kennedy.
"I can remember sitting in my eighth-grade class and the shooting was announced over the public address system. I cried then and tonight brought it all back to me as I listened to Mr. Hill describe those moments in Dallas. I can clearly remember going home and sitting with my parents while we watched everything on TV for the next four days," said the Steubenville woman.
Hill and journalist Lisa McCubbin were joined by nearly 1,000 people Wednesday night for the inaugural lecture in the Jefferson County Chamber of Commerce Lecture and Concert Series for a discussion on Hill's four- year assignment to protect first lady Jacqueline Kennedy.
Article Photos
SHARING MEMORIES — Retired U.S. Marshal John Chernenko of Wellsburg shared memories of working for the Kennedy administration in the early 1960s with retired Secret Service Agent Clint Hill. Hill and journalist Lisa McCubbin spoke Wednesday evening at Steubenville High School during the initial lecture of the Jefferson County Chamber of Commerce Lecture and Concert Series. -- Dave Gossett
The event, which was held in the Steubenville High School auditorium, was sponsored by the chamber; the Herald-Star and The Weirton Daily Times; Eastern Gateway Community College; and the Franciscan University of Steubenville. Also supporting the event were Bayberry Bed and Breakfast, Apollo Pro Cleaning, Piergallini Catering, Steubenville City Schools, Thrifty Car Rental, D'Anniballe and Co. CPAs and McCauslen's Florist.
The lecture featured McCubbin asking Hill questions and Hill vividly recalling details of the Kennedy family that were at times funny, moving and, finally, very sad.
Hill described his initial reluctance to accept the assignment to provide protection for the first lady.
"I had worked on President Eisenhower's detail and remembered Mrs. Eisenhower going to tea parties and fashion shows. When Mrs. Kennedy returned to her home in Georgetown following the 1960 election, I went to meet her. She didn't want me there because she didn't want someone looking over her shoulder and I didn't want to be there. But eventually we became very close friends," related Hill.
He went on to discuss Mrs. Kennedy's decision to rent a farm in Virginia where she could go horseback riding with her children, Caroline and John.
"Do you see that white building? Those were the stables. The horses were on the first floor and the agents were on the second floor," he chuckled.
The talk was interspersed with black-and-white photos and videos including a short clip of Hill walking on the beach with young John Kennedy.
"But, he soon wanted to go back to the boat to see his mom and dad. That was my day ... taking the kids to the boat and back to the shore and back to the beach. It was every day when the Kennedys were vacationing," he said.
Hill also discussed Mrs. Kennedy's frequent overseas trips including a 10-day visit to India and Pakistan.
"The president of Pakistan wanted to present her with a horse, and you can see the smile on her face. But all I was thinking about was how was I going to get the horse and two tiger cubs from India back to the United States. We then went to visit the Khyber Pass but had to pass through an area controlled by tribal chiefs who wanted to pay tribute to the first lady. And they wanted to sacrifice a lamb in her honor. I told them to take the lamb behind the tent and do whatever they wanted to do with it, but don't do it in front of Mrs. Kennedy," recalled Hill.
As he continued to share stories of his job and the Kennedys' life the mood in the room became more somber.
"She decided to help her husband's bid for re-election in 1964. And as you can see in these photos everywhere they went the crowds would be in the streets and hanging out of nearby building windows. Everyone wanted to touch the president and be near him as he traveled through a city in an open car. That was typical wherever we went," Hill explained.
"We started planning the campaign trip to Texas that included five cities. On Nov. 21, we arrived in San Antonio and then to Houston for a fundraiser for a congressman. We then flew to Fort Worth to spend the night. At 8 a.m. the next day the president gave a speech in a light rain outside of the hotel and in the photo you can see approximately 5,000 people gathered in the street and open windows in nearby buildings. You have to remember this was before air conditioning was common and windows were often opened for fresh air," Hill said.
"We then flew to Dallas and put the president and first lady in the limousine with (then-Texas Gov. and Mrs.) John Connally. The crowds along the streets began to build and build until they were actually standing in the street," he continued.
"The cars made the sharp left turn onto Elm Street to approach the underpass. We had gone about 100 feet when I heard a loud explosive noise. My vision went toward the noise behind me and that's when I saw the president grab his throat. I ran toward his car and never heard the second shot. I then saw him fall over into Mrs. Kennedy's lap," stated Hill.
"When we got to Parkland Hospital, Mrs. Kennedy wouldn't let us take the president of the car. Then I realized she didn't want anyone to see the condition he was in. So I took off my suit coat and covered his head and back and she let us take him out of the car and put him on a gurney," recited Hill to a silent audience.
"I was asked to call the White House to tell them what was happening. I was talking to my supervisor when the operator broke in to say the attorney general wanted to speak to me. That's when the president's brother, Robert Kennedy, came on the line and asked what had happened. I couldn't tell him his brother was dead so I simply said it is as bad as it can be," explained Hill.
Hill said the funeral procession to Arlington National Cemetery was completely silent. Normally the motorcade would have cheering crowds and flags waving. But the only sound that day was the drums and the clop, clop, clop of the horses pulling the wagon carrying the casket. The entire world stopped for those four days in November."
Hill would serve on the protective detail for another year before being assigned to other duties.
"But she remained my friend," he said to a standing applause from the audience.
Ann Koon, director of public information at Eastern Gateway Community College, thanked Hill for writing the book, 'Mrs. Kennedy and Me', "because he caught a piece of history."
"I thought tonight was wonderful because we have his perspective on that part of history. His memory is still very remarkable and we were fortunate to have Agent Hill share his story with us. You could feel the pulse in the room when he started talking about Texas. You know what is coming and I think everyone dreaded hearing about that day. But it was unique hearing about the day from his perspective," said Koon.
"I thought it was good to hear from someone who was there. We have read about President Kennedy and the assassination in class but he was there and talked about it," noted Steubenville High School senior Ryan Ledakis.
"I thought our first lecture was fantastic. Tonight was touching and sad. And at times we literally held our breath," said Jefferson County Chamber of Commerce President Sue Hershey. People are already asking who our next speaker will be in the spring."
(Gossett can be contacted at email@example.com.)


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when you have 6 men and 1 girl. 5 of the men have condoms on, and one doesn't. The one girl has to decide blind in a dark room which one to have sex with.
When someone puts a revolver to their head with only 1 out of 6 bullets inside, that person is playing Russian Roulette. This is only dirtier, and is something seen by a man called Frank Moore.
by parkerh. May 24, 2010
Trending Now
Top Definition
A sexual act involving 7 people. One person stands blindfold and pants-less while the other 6 form a circle around with their bare asses facing inwards while bending over, grabbing their ankles. The person in the middle spins around and then thrusts, trying to penetrate one of the six asses. If the thruster is a woman a strap on is required.
I lost last night and got ass fucked playing russian roulette. Next time I want to be the bullet.
by Pandacoon January 11, 2012
A dangerous and deadly game in which a revolver or six shooter has one ( or more) bullets put into the chamber. The chamber is then spun around and snapped into position, leaving no idea as to the bullet's exact position. Two or more men then take turns putting the gun to their head and pulling the trigger, hoping it falls on an empty chamber. Others will commonly bet on this sort of game. Russian roulette may also appear in the form of a similar game in which many glasses full of some substance are placed down. All but one are filled with water or alcohol or something, the last containing deadly poison. Men take turns choosing and picking glasses to drink until one dies. (I think this is also called russian roulette)
Damn yo, that scene with russian roulette in The Deer Hunter was intense!11
by Noobert January 23, 2003
A game where a revolver with one bullet is placed and spun. Then you take turns putting the gun to your head and pull the trigger. If it's empty, you pass it on until someone dies or becomes extremely injured.
Peter: Russian Roulette, three bullets to the head, last man standing gets the trophy. Me first! No wait... this is crazy. You first...
by Species October 22, 2004
Russian Roulette is A stunt in which one spins the cylinder of a revolver loaded with only one bullet, aims the muzzle at one's head, and pulls the trigger
In movies, the bad guys do Russian Roulette to scare the other person.
by AHHHHHHHHHHHHHHHHHH January 24, 2006
Engaging in a creampie gangbang with an ovulating chick.
Damn! Me and some hommies busted a nut in some bitch last year playing Russian Roulette and now I'm on Maury Povich.
by Crazy8888s January 25, 2011
this isn't a definition, it's just a (disturbingly) humorous tale. It's documented in a recent Darwin Awards - collections of stories where people, either through accidental self-castration or accidental self-homicide, remove themselves from the gene pool - that a police officer was recently a victim of this risky game of chance. however, instead of using a revolver, with only one chamber in six loaded, he was using a semi-automatic pistol, having loaded one round into the magazine and pulled the slide back. some of you can already tell what happened, but let me explain for the rest: with a semi-automatic pistol, the top round in the magazine is automatically (hence a semi-AUTOMATIC pistol) inserted into the chamber. instead of a 1 in 6 chance of shooting himself, the cop had a 1 in 1 chance......
note: i'm not sure if he was intoxicated at the time. also, for more intriguing stories, search with your fav search engine for 'darwin awards'
note: i'm not sure if he was intoxicated at the time. also, for more intriguing stories, search with your fav search engine for 'darwin awards'
by sum guy January 28, 2003
The deadly game Ronnie Radke mentions in "Not Good Enough for Truth in Cliche".
"Sitting in this room playing Russian roulette, finger on the trigger to my dear Juliet.."
by Anaaaaaaaaaaa April 05, 2008


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If you are a recruiter or admissions counselor and you would like to do an event on the UIS campus please contact Prof. John Martin (217-206-8342, firstname.lastname@example.com).
If there is no room listed for an event then it should be considered tentative and subject to change.
Fall 2013
December 5: Physician's Assistant Speaker
(7 pm, UHB 1002) Tony Grasch, PA-C will be coming to talk with us about what it is like to be a PA. Tony is a PA in cardiothoracic surgery at SIU School of Medicine, the regional director of the Illinois Academy of Physician's Assistants, and is very involved in the training and selection of students at the SIU School of Medicine Physician's Assistant program. He will have some very useful insight on the career, its history, and its present state. Even for those of you who are not currently considering PA school, it is good to know your options. The PA path is becoming very popular and widespread.
November 8: Med School Discussion
(4 pm, HSB 302) Mark Frakes, 2nd Year Medical Student at the University of Illinois Medical College Rockford, and UIS graduate will talk about his experience applying, interviewing and succeeding in medical school. Pizza and drinks will be provided in the 3rd floor Lunch room.
Fall 2012
September 19: PreMed Club Meeting
(noon, HSB Lounge on 1st Floor) First fall meeting of the UIS Pre-Med Club.
September 20: Illinois RMed Scholarships
(3pm, HSB 302) Come meet Illinois RMED program recruiter Mark Meurer and learn how this program can help you pay for medical school.
What We Did Last Fall (2012)
September 28: Illinois RMED Scholarships
(1pm – 2pm, location HSB 235) Come meet Illinois RMED program recruiter Mark Meurer and learn how this program can help you pay for medical school.
October 3: Research and Graduate School is Parmacology at the SIU School of Medicine(noon – 1pm , location TBD) Dr. Julio Copello from the SIU-SOM Pharmocology dept on will talk about his research and their graduate program. This talk is arranged and hosted by the BIO and CHE departments.
October 26: Philanthropy and MedicineDrs Robins & Woodson, Simmons Cancer Institute, SIU Med(1pm – 2pm, location HSB 302) Discussion about how many doctors give their time and talent to charitable cases.
November 30: Effects of the Affordable Care ActDr Eric Brown, Cheif Medical Officer for SIU HealthCare at SIU-Med Springfield(1pm – 2pm, location HSB 302) Learn how changes to the law and public policy are effecting the work of medical professionals.
What we did last Spring (2013)
January 30: Pre-Med Student Club Organizational Meeting
(11:30am – 12:30pm: UHB 2001) A new pre-med student club is starting at UIS! Come be involved from the start. If you can't be there but are intrested talk to Josh Huber, Justin Sawyer, or Jacob Bohem about being part of this.
February 11: Med-School Recuiter from A.T.Still University
(4pm – 5pm, HSB 235)
February 12: Recuiter from Life University School of Chiropracty
(4pm – 5pm, HSB 235)
February 26: Med-School Recuiter from Universidad Autonoma de Guadalajara
(4pm – 5pm, HSB 303)
April 5 : Illinois R-Med Program
(1pm – 2pm, location HSB 304) Mark Meurer will be visiting with information about the Illinois R-Med program that offers scholarships to medical students you plan to serve in rural Illinois communities.
April 26 : Applying to Medical School
(1pm – 2pm, HSB 304) This is one of our most popular events every year. Dr Erik Constance. associate dean of students at SIU-Med, will be on hand to tell you about what you need to know about medical school before you apply.
(6pm – 7pm, VPA 152) Don Diemer, DHSc, PA-C is the Program Director of the SIU Physicians Assistant Program and the President of the Illinois Academy of Physician Assistants. He will be talking about what physician assistants do and how to become one.


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I have 2006 VW beetle with the 2.5L engine. Once the engine has warmed to operating temperature, and I am driving it around, the heater works great. As soon as I stop at a red light, or am idling for any length of time the air coming out of the vents begins to lose temperature until it blows cool air. All I have to do to get hot air again is give it a little gas, say 200 more rpms, and the heater immediately responds with warmer air, hot air if I maintain 1000 rpms. I have read related information on here and think that if the heater works great at other times, I do not have a blender door issue, clogged heater core, or low coolant level. The coolant level is fine, by the way. Any help would be greatly appreciated!
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You most likely have air trapped in the cooling system. The air needs to be burped out. The method varies by make ,model, year etc. Due to variation between models can you tell us what country the car was made for?
Problem solved! The key was to finally locate the source of OBDII code PO 0171, left bank lean, which I realize was not part of my original question. Anyways, I found a leaky air hose connection between the manifold and the MAF, once I corrected it, the engine idle smoothed out and now we have heat as designed at idle.


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The Emperor Constantine who favored Christianity as early as 312, and convened the Council of Nicæa in 325, postponed baptism till 337. Did he provide any reasons for doing so?
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I do not think anyone knows as there is huge speculation on the subject.
Basically some see it as his cowardice to confess his faith, others see it as a prudent measure to keep his influence of power until the risk of his own execution for becoming a Christian had passed. He himself does not seem to say. I do not even believe we can prove He was a Christian. Maybe he was? God only knows.
It does seem though the God used Him to end so much Christian persecution, and it does seem that in some ways, at least initially, Christ overthrew the Gentile world by turning his heart in favor of His people. Quite soon after his death, Christ's kingdom grew like a mustard seed.
The chief reason that people put off Baptism had to do with the Roman tendency to be almost magical in their thinking about religion. Even when they had converted in their hearts, people who had civic duties, which inevitably involved performing some pagan rites, were extremely reluctant to break with tradition. And Roman society in general didn't tolerate such omissions. So, a person could only convert when he could finally be sure he wouldn't have to perform such rites.
That didn't stop many of the famous martyrs, especially soldiers like St. Sebastian and St. Vincent. But as an EMperor Constantine simply could not do what was expected of him. So he hedged his bets, kept doing his imperial thing, and on his deathbed converted.


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Disconnect The Dots
Of Montreal
Last Played
AlbumSatanic Panic in the Attic
Average rating
4 star rating.
Other songs by this artist
- 89.3 In-Studio Performance
- An Eluardian Instance
- Enemy Gene feat. Janelle Monae
- Feminine Effects
- Flunkt Sass vs. The Rute Plume
- Fugitive Air
- Hegira Emigre
- Party's Crashing Us
- Repudiated Immortals
- She Ain't Speakin' Now
- So Begins Our Alabee
- The Kids Are Alright
- Tonight
- Touched Something's Hollow
- Triphallus to Punctuate
- Trouble
- Aureate Gloom
- Bassem Sabry
- Empyrean Abattoir
- Deflated Chime, Foals Slightly Flower Sibylline Responses
- Noir Blues To Tinnatus
- Psychotic Feeling
- False Priest
- Coquet Coquette
- Enemy Gene feat. Janelle Monae
- Famine Affair
- Our Riotous Defects feat. Janelle Monae
- For The Kids 3
- I Want To Have Fun
- Hissing Fauna, Are You The Destroyer?
- A Sentence of Sorts in Kongsvinger
- Heimdalsgate Like a Promethean Curse
- Suffer For Fashion
- The Past is a Grotesque Animal
- Live Current Vol. 1
- Repudiated Immortals
- Lousy With Sylvianbriar
- Fugitive Air
- Paralytic Stalks
- Dour Percentage
- Spiteful Intervention
- Purplish Rain
- Computer Blue
- Satanic Twins
- Forecast Fascist Future (IQU Remix)
- Requiem for O.M.M.2 (United State of Electronica Remix)
- Wraith Pinned to the Mist and Other Games (Broken Spindles Remix)
- Skeletal Lamping
- An Eluardian Instance
- Id Engager
- The Gay Parade
- Jaques Lamure
- Neat Little Domestic Life
- Old Familiar Way
- The Autobiographical Grandpa
- The March Of The Gay Parade
- The Miniature Philosopher
- The Sunlandic Twins
- Forecast Fascist Future
- I Was A Landscape In Your Dream
- I Was Never Young
- Oslo In The Summertime
- The Repudiated Immortals
- Wraith Pinned To The Mist (and other games)
Please note that our catalog only lists songs that we've set up within our system; not every track from an album is displayed. You may request a song that's not in our catalog by using our request form. You may also suggest a song be added to our catalog by contacting The Current.
Album art and preview audio provided by iTunes, related artists provided by EchoNest.


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Monkeypox (cont.)
Charles Patrick Davis, MD, PhD
Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
Mary D. Nettleman, MD, MS, MACP
Mary D. Nettleman, MD, MS, MACP is the Chair of the Department of Medicine at Michigan State University. She is a graduate of Vanderbilt Medical School, and completed her residency in Internal Medicine and a fellowship in Infectious Diseases at Indiana University.
In this Article
- Monkeypox facts
- What is monkeypox?
- What is the history of monkeypox?
- What causes monkeypox? How is monkeypox transmitted?
- What are risk factors for monkeypox?
- What are monkeypox symptoms and signs?
- How is monkeypox diagnosed?
- What is the treatment for monkeypox?
- What is the prognosis of monkeypox?
- Can monkeypox be prevented?
- What research is being done on monkeypox?
- Where can people get more information about monkeypox?
What is monkeypox?
Monkeypox is a relatively rare disease that was first detected in monkeys in Africa in 1958 and resembles smallpox in terms of the skin lesions (pox) seen in humans as part of the physical findings and also because the cause is a virus that is closely related to the smallpox (variola) virus. Monkeypox, smallpox, cowpox, and vaccinia viruses all belong to the same family of viruses, the Poxviridae. Monkeypox belongs to same genus (Orthopoxvirus) as smallpox. The disease is different from smallpox. Monkeypox may be transferred from animals to people (or person to person) and has far less mortality (death rate) than smallpox had. Monkeypox virus is endemic in rodent populations in Africa. Smallpox did not infect any endemic animal population. The press and bloggers have occasionally tried to link monkeypox to other diseases such as mad cow disease, Ebola, leprosy, yellow fever, and other viral and immunological diseases, but there is no scientific evidence for this.
What is the history of monkeypox?
Monkeypox has a relatively recent history. It was first discovered in monkeys in 1958, although a "vesicular disease in monkeys" was described in the1860s. The disease, and eventually the causative virus, was named monkeypox because the lesions (pox) seen in monkeys developed like other known pox-forming diseases (pustules that eventually break open, ulcerate, crust over, and some pox form scars in the skin). Later studies showed the "monkeypox" virus was actually sustained endemically in African rodents. It was not until 1970 in Africa (Zaire, now the Democratic Republic of Congo), when a 9-year-old boy (who developed smallpox-like lesions) was the first person to eventually be diagnosed with monkeypox. This situation initially caused concern that smallpox may also have an animal reservoir or endemic population that would make eradication of smallpox impossible. Fortunately, this was not the case because monkeypox was found to be a different species of pox virus, and smallpox was eradicated from the human population by vaccinations in 1979 (currently, only a few research labs have access to smallpox viruses). Monkeypox is now the major Orthopoxvirus that infects humans and fortunately, not frequently. However, vigilance is warranted as there have been several outbreaks of monkeypox since the 1970s. Although most have occurred in Africa (mainly western and central Africa), there was an outbreak in the U.S. in 2003. This apparently happened when an animal distributor either housed or transported monkeypox-infected African rodents (Gambian rats) with prairie dogs that were later purchased as pets, became "sick," and transmitted the disease to their owners.
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Find out what women really need.


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When Volvo introduced both the FL6 and the FL7/FL10 family of heavy-duty trucks in the summer of 1985 it was a demonstration of strength. Both families of trucks were completely new and had leading characteristics compared with other competitor-made trucks in the same segments.
Light-weight and very powerful
The FL7/FL10 trucks constituted a completely new class of truck, combining the efficiency and light weight of their predecessor, the F7, with the option of a very powerful 10-litre engine with engine output of up to 318 bhp. The driveline components were identical to the driveline components of the F10 truck, which meant that the FL10 trucks (the most powerful of the two new trucks) were very suitable not only for heavy-duty distribution but also for construction-site operation.
They were also suitable for regional transport or long-distance transport where the low roof of the FL7/FL10 or a low maximum height for the complete truck was of importance.
Steps towards increased driver care
Traditionally, long-distance high-built heavy-duty trucks have been the subject of advanced design while distribution trucks and trucks with lower GVW have not been as good ergonomically when it comes to aspects such as driver comfort, sound insulation, cab suspension etc. In this respect the FL7/FL10 meant a radical step towards driver care for this class of vehicles as well.
Very sophisticated cab suspension, even more efficient than on the F10/F12, was the most important factor behind the exceptional comfort provided for the driver and his passenger. Another factor, which contributed in this respect, was the dashboard, which was designed to have all instruments and handles within sight and easy reach of the driver.
The art of multi-purpose
The most obvious new feature of the new FL7/FL10 trucks was, of course, the completely new cab, which was extremely spacious for a low-built truck of this type, not least due to the fact that the new cab had a full-width of 250 cm (in contrast to the F7, which had a width of 230 cm).
The new family of low-built trucks were true multi-purpose trucks like their predecessor F7 so it was natural for Volvo to offer a full range of cabs, including a short day cab for maximum payload and load area within a given overall length, a spacious sleeper cab with a full length single bunk, and also a crew cab for community service vehicles such as fire trucks.
Advanced chassis specifications
Efficiency (together with improved ergonomics) was the key word for the new range of vehicles. That was the reason for the very advanced chassis specification, which could be supplied in a large number of models, including two, three and four-axle vehicles. These could be driven on one, two or three axles, with numerous suspension alternatives including full air suspension on all axles, which contributed not only to extremely good cushioning for the payload and comfort for the driver, but also to very fast exchanges of different load carriers.
The FL7 and the FL10 became very popular in a large number of countries. In some countries, e.g. Great Britain, it became by far the most popular of all Volvo trucks.


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The Zega Pro topcase rack from Touratech is the strongest and most secure option for mounting a topcase to your Suzuki V-Strom DL650.
Made of electro-polished stainless-steel, this topcase rack is set up to accept any one of the Rapid-Trap Zega Pro topcases from Touratech. The strong framework of the rack is engineered to be extremely robust and keep your top case firmly attached.


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Bayern's Success Has a Downside
Bundesliga Must Guard Against Every Season Becoming a One-Horse Race
On Saturday, Bayern Munich became champion of Germany for the 23rd time, winning 1-0 at Eintracht Frankfurt.
Between the records it has already set, those it's likely to set and those it might yet set, the Bundesliga's statistics collectors will be kept busy.
Nobody before has been crowned this early, with six games to go—the previous mark was four. Bayern's 11 consecutive league wins are also a single-season best.
Project Bayern's numbers out for the rest of their campaign and it will easily shatter the single-season bests for points (91, compared with the previous record of 79), wins (29 to 25) and goals conceded (16 to 21). It also has a decent shot at tying the mark for fewest losses (one).
Just as telling as the records is the gap over the competition. Borussia Dortmund in second place is a full 20 points back.
The club is also still alive in the two other major competitions it entered this season. In the German Cup, Bayern is through to a semifinal clash with Wolfsburg, while in the Champions League, it takes a 2-0 advantage into a return leg against Juventus JUVE -0.51 % in the quarterfinal second leg on Wednesday.
And in a classic case of the rich getting richer, when 68-year-old coach Jupp Heynckes retires at the end of the season, he'll be replaced by none other than Pep Guardiola, former boss of Barcelona, who "only" won three Spanish League titles, two Spanish Cups and two Champions' League crowns in his four years of top-flight management.
While still outranked by England's Premier League, Spain's Liga and Italy's Serie A in terms of broadcasting dollars and ratings, the Bundesliga's overall appeal is undoubtedly growing. It boasts the highest average attendances in the world, solid governance and oversight and low ticket prices, as well as fast-paced games that are well-suited to TV.
The common practice of using sponsor revenue and club seats to cross-subsidize cheap tickets has fostered goodwill and proved a winner. With La Liga and Serie A reeling under mountains of debt, many see it as the fan-friendly alternative to what can sometimes feel an over-hyped and over-commercialized Premier League.
Yet you wonder if Bayern's hegemony might not be to the detriment of the Bundesliga's rise. Borussia Dortmund won the league the previous two seasons, but that might simply have been an outlier, a prodigious result achieved by a great manager, Jürgen Klopp, and a core of young talent assembled on a shoestring, coupled with Bayern's own failings and poor decisions. If that was an outlier, then this year is the status quo.
Simply put, Bayern is a commercial juggernaut dwarfing all it surveys. According to Deloitte's Football Money League report, a survey of Europe's top clubs by revenue, Bayern's turnover of $476 million is more than the next two highest ranked German clubs—Borussia Dortmund and Schalke 04—combined. Oh, and it's worth mentioning that last season Bayern made a profit of $14.3 million. That marked the 20th consecutive year that the club finished the season in the black.
This translates into transfer market muscle. According to figures from the respected website Transfermarkt, Bayern was responsible for almost a third of total Bundesliga spending in 2012-2013.
What's more, the club tends to splash the cash to acquire talent from its direct competitors.
In the past three seasons, it has raided Borussia Mönchengladbach (for defender Dante), Werder Bremen (for forward Claudio Pizarro), Wolfsburg (for striker Mario Mandzukic) and Hoffenheim (for midfielder Luis Gustavo), at once strengthening its squad and weakening the opposition.
People complain that Spain's superclubs—Barcelona and Real Madrid—dominate La Liga financially. And they do, but at least there's two of them. In Germany, Bayern stands alone.
The counter argument is that it has been this way for a while and yet the rest of the Bundesliga has found ways to compete. It's true that in the decade before this season, five different clubs were crowned German champions, which compares favorably to England (four), Italy (three) and Spain (three).
The problem is that none of the other clubs to have won the Bundesliga has managed to build sustained success. Werder Bremen, champion in 2003-2004, is currently 14th and has finished outside the top eight in three of the past four seasons. The 2006-2007 winner, Stuttgart, is 13th and has finished in the top five just once since conquering the Bundesliga. And Wolfsburg, which won it in 2008-2009, is in 12th place after finishing eighth, 15th and eighth in the three seasons following its title.
That's why the Bundesliga needs a competitive Borussia Dortmund to challenge Bayern in the next few seasons and, ideally, maintain a sustainable rivalry over time.
But when pitted against Bayern's enormous financial advantage, that's a tall order indeed. And with UEFA's Financial Fair Play—a set of regulations that limit the amount of losses a club can sustain over a given period—now in effect, Bayern's competitive advantage will only increase.
In the medium term, that could be a serious problem for the Bundesliga cheerleaders. The league may be an example of "best practice" in soccer, but if every year turns into a one-horse race like this one, it could be a turnoff to fans.


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WOODSFIELD - For one day, Woodsfield is expected to disappear and become "Whoville," the home of Dr Seuss' fictional "Whos" and site of the legendary Christmas heist of the green, Yuletide-hating Grinch.
This decorating scheme is part of the downtown window decorating contest and parade, two of several events planned for the seventh annual Woodsfield Christmas Festival on Dec. 8.
"We've got a lot of people excited about this," said Ruth Workman, a member of the Woodsfield Christmas Festival Committee. "I think it's going to be a lot of fun this year."
The Monroe County Courthouse and downtown were decorated by the Woodsfield Garden Club and the village electric workers, while Christmas figures made by Woody Mobley have moved from their usual site in the city park to the downtown in an effort to increase the festive atmosphere.
The Kiwanis Club of Woodsfield will begin the festival with Breakfast With Santa at the Brown Community Center from 8:30-10:30 a.m., followed by a shopping opportunity for children at St. Sylvester Central School. Open from 10 a.m. to noon, Santa's Gift Shop will give children a chance to do their Christmas shopping in a safe, community setting, while all proceeds will go to the Warm the Children charity.
This year's festival features a number of family- friendly events. From 11 a.m. to 2 p.m., there will be pictures taken with Santa Claus at Pat's Gift Shoppe. The Monroe County Library will have a reading of Dr. Seuss' "How the Grinch Stole Christmas" at noon, and carriage rides will run from noon to 4 p.m. from Eastern Row Market.
An annual craft show in the courthouse will give local vendors and artisans a chance to sell their wares from 9 a.m. to 4 p.m. The bazaar has grown this year to accommodate a large artisan turnout.
"This year, we asked the county for three floors," said Myrna Morrison of the Monroe County Chamber of Commerce.
She said in previous years, the use of two floors was just not enough, and that created crowding problems. The courthouse will also host a gingerbread creation contest from 9a.m. to 3 p.m.
From 9 a.m. to 4 p.m., there will be a Christmas Ornament Walk and a "Deck the Halls, Walls and Tables" silent auction at the chamber office. The United Methodist Church will also have a Christmas Bazaar from 9 a.m. until the baked goods supply runs out.
The festival will continue into the evening, starting with a live nativity scene from 4-6 p.m. in front of the Monroe Theater. The Monroe Central Band will perform at the courthouse from 5-5:30 p.m., while free hot chocolate will be served at the Monroe Bank Building from 5:30-6:30 p.m.
Lineup for the Lighted Christmas Parade will begin at 5 p.m. at the old Woodsfield Elementary School, the grand marshal being the Grinch himself. The parade will begin at 6 p.m. and end with a poetry reading by Dorothy Ricer and the lighting of the courthouse Christmas tree.
A Victorian Christmas Candlelight Tour will set out from the Hollister-Parry Museum on Eastern Avenue from 6-8 p.m., and a "Traditional Christmas" concert by the Monroe Singers will be performed at St. Paul's Church at 7 p.m.


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1997 Ford Thunderbird, pulls right while driving intermittenly, always pulls left while braking. It makes a loud noise while driving, but when the front end is on jackstands, and no weight on the wheels, it stops making the sound. it is not the power steering pump making the sound, the brake pads on both sides are in tact, and less than a month old, the tires are new, alignment was done, no parts on the suspension are loose enough to make them budge /at all/ by hand. Any ideas would be helpful.
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Check the condition of the brake flexi hoses. These perish over time, and can often clug inside, effectively either locking the relevant brake on or preventing it from applying fully, thus casuing the car to pull to the side.
Suspension bushes can be worn enough to cause issues without being bad enough to move by hand - try using a small lever to move them and see if anything there looks suspect.
Thunderbirds are rear wheel drive aren't they? Have you checked the rear suspension as well? The symptom of a car pulling one way when driving and the other when braking is typical of worn suspension bushes on one or more driven wheels, allowing the wheel in question to pull forward under power and drag backward under braking.
Check the donut shaped strut rod bushings that go into the control arm. They look like rubber donuts. Have someone sit in the car and drive it back back and forth when they hit the brake. If the bushings are bad you will see the wheel actually move when you hit the brake.
Secondly check the ball joints. jack up the control arm so the weight of car rests on it and check for any play. They are known to fail on these cars. You should replace the entire arm if that is the case.


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Jared Remy's relatives convinced Jennifer Martel not to file a permanent restraining order against her live-in boyfriend when he allegedly assaulted her this past week, Martel's family said Friday.
"That was not done, and it ultimately led to her death," Richard Martel, Jennifer's uncle, said Friday outside his Fall River home. Martel and his daughter, Amanda, stayed home from work to grieve for Jennifer Martel, who died Thursday night from multiple stab wounds. She was 27.
"It's just unbelievable," Richard Martel said, adding that he feared this day would come.
"I always used to say she was going to end up dead ... He was always hitting her," Martel said.
Jared Remy — the son of Red Sox legend and Somerset native Jerry Remy — is charged with Jennifer Martel's murder. He was ordered held without bail after his arraignment Friday in Waltham District Court. Remy pleaded not guilty to charges of murder and domestic assault and battery.
Richard Martel said his niece dated Jared Remy, 34, for about five or six years and they had a 4-year-old daughter together. The child is currently in the custody of the state Department of Children and Families. Jennifer Martel's parents — who were traveling Friday from Virginia — plan to take custody of the child, relatives said.
The child was in the Waltham apartment when her mother was killed, authorities said. During Remy's arraignment Friday, prosecutors described a "vicious attack," and said Remy repeatedly stabbed Martel while he was on top of her. When Remy was arrested, he was covered in blood, prosecutors said.
Richard Martel said his niece's relationship with Jared Remy was "volatile." He said Remy was "tough" on Jennifer and insulted her mother when her parents visited. Remy, relatives said, was possessive and violent, and had isolated Jennifer from her family. Richard Martel said he had never met Remy.
"She had to deal with his attitude, but she loved him and had a child with him," Martel said. "She was a good mother to her baby. She tried to make it work."
According to WCVB-TV, a GateHouse Media partner, records show that police arrested Jared Remy at the couple's Waltham apartment complex on Tuesday night. Remy was charged with assault and battery, and was released Wednesday on personal recognizance after being arraigned in Waltham District Court, Middlesex District Attorney Marian Ryan said.
Jennifer Martel was granted a temporary restraining order on Tuesday night, but she declined to extend it the next day at court.
In the past few days, Jennifer Martel sent out emails to friends to say she was scared, her uncle said, adding that she changed her Facebook status on Thursday from "in a relationship" to "it's complicated." Richard Martel Sr., Jennifer's grandfather, said Jennifer was looking to end the relationship.
Page 2 of 3 - Amanda Martel, Jennifer's cousin, said she met Jared Remy on one occasion.
"He seemed really nice at the time," she said.
A business partner posted on Jerry Remy's official Twitter account Friday that the Remy family's "thoughts and prayers go out to the Martel family."
Relatives remembered Jennifer Martel as a kind-hearted young woman who was an avid sports fan and loved her family and friends.
"She was kind and outgoing. She didn't have a mean bone in her body. I never saw her being rude to anybody," Richard Martel said.
Jennifer Martel was born in Arizona, but her parents moved back to Massachusetts when she was young. She grew up in Dartmouth, Fall River and Taunton. She was one of two children of Brian and Patricia Martel, who live in Franklin, Va. Her brother, Brian Martel Jr., also lives in Virginia with his wife and children.
Jennifer Martel graduated from Taunton High School in 2004. In her yearbook write-up, she said she would miss football games, homecoming dances and hanging out with friends.
"She was very, very loving," Amanda Martel said.
"I never heard her swear. She was just a beautiful person. She wanted to better herself," Richard Martel said.
Jennifer Martel was studying to become a teacher and worked at a Market Basket to pay expenses, relatives said. Richard Martel said he plans to open a memorial fund in Jennifer's name to help the family pay for burial expenses.
"Jenn was an outgoing person who liked to have fun. I had never seen her yelling at anybody. She had a good personality. She worked hard, she worked at various places, sometimes two jobs, and never complained about it," Martel Sr. said.
Richard Martel Jr. said his niece used to play all the time with his daughter.
"She used to baby-sit my kids. We used to be together all the time," he said.
Employees at Market Basket in Raynham who worked there with Jennifer Martel during her stint as a part-time employee remembered her as being well-adjusted and personable.
"She was a very nice girl … fun to be around and very outgoing," Nancy Nichols said.
Nichols said she couldn't recall the exact year Martel worked at the Route 138 store, but she said Martel at the time appeared to be about 19.
Nichols, 47, said she was a supervisor for the front of the store when Martel was working as a part-time cashier.
"I never got to know her well, but she was pleasant to work with," Nichols said.
Three restraining orders have been taken out under Jared Remy's name since 2005. He was the defendant in two and the plaintiff in one, court documents said.
Page 3 of 3 - Jared Remy was fired from his Fenway Park security job in 2009 after he and another guard were implicated in a steroid use scandal.
In 2005, Jared Remy was arrested and charged with assault and battery after he was accused of beating up his then-girlfriend at his father's Weston home.
GateHouse Media partner WCVB, reporters Eli Sherman and Meghan Kelly of the MetroWest Daily News, reporter Charles Winokoor of the Taunton Daily Gazette and The Associated Press contributed to this report.
Email Brian Fraga at firstname.lastname@example.com.
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Good lord, November is all about:
SKYRIM - After 30 hours (plus an additional 10 on another console) with this all encompassing monster, and as a huge fan of Bethesda's past open world epics, Skyrim is simply put: the best goddamn game I have ever played.
The enhancements and tweaks made to the tried and true formula has made the style infinitely more accessible without dumbing anything down or oversimplifying (if anything I'd say it's MORE complex than Oblivion), the combat feels great in first or third person, and the world is insanly HUGE, PACKED with detail (Salmon jumping up waterfalls?) and drop dead gorgeous.
On top of all that, there's an extremely fine plot weaving through the main quest with branching points, every side mission feels like an epic all it's own, and the Nordic-traditional Fantasy cross feels more like Robert E. Howard's original Conan stories than I expected. This is just... just goddamn STUNNING!
Also, Dragons, sweet christ on a cracker the Dragons...
This is the ultimate time sink. This game will rend families asunder.


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Weight Loss Impressive, but Safety Questions Remain
Nov. 9, 2011 -- The FDA is again considering approval of an experimental weight loss drug it rejected a year ago over concerns about potential heart problems and birth defects in babies born to women who take the drug.
California-based pharmaceutical company Vivus Inc, is now asking for limited approval for its oral combination drug Qnexa, which would exclude women in their childbearing years.
According to the company, the FDA is scheduled to make an approval decision next April. If approved, the drug could be commercially available soon after that.
That would make Qnexa the only prescription appetite suppressant approved for long-term use available in the U.S. The only other widely marketed prescription weight loss drug, orlistat -- sold by prescription as Xenical and over-the-counter as Alli -- works by blocking dietary fat absorption.
In a study submitted to the FDA last year in Vivus' original filing, and published in the journal Obesitylate last week, people who took the highest dosage of Qnexa for a year lost, on average, about 14% of their body weight. They showed improvements in blood pressure, cholesterol, triglycerides, and blood sugar.
Qnexa Combines Two Drugs
Qnexa combines low doses of the stimulant phentermine -- long used for short-term weight loss -- and the anti-seizure and migraine drug topiramate, which has also been used "off label" to treat binge eating. "Off label" refers to drugs that are prescribed by doctors as treatments for conditions that are not specifically approved by the FDA.
Last fall, an FDA panel voted against the drug's approval, citing North American drug registry data showing that babies born to women who took topiramate had up to a 20-fold increase in cleft palates.
Vivus Inc. president Peter Tam tells WebMD that subsequent investigations involving other databases suggest that the risk for the oral birth defect is actually much lower.
Based on the new information, the FDA agreed to let the company resubmit its application for limited approval for use in adults who are not likely to become pregnant.
At the request of the FDA, the company is also examining more than a decade of medical claims records involving women who took topiramate during pregnancy to treat seizures, migraines, and other conditions, Tam says.