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In undergraduate differential equations it's usual to deal with the Laplace transform to reduce the differential equation problem to an algebraic problem. The Laplace transform of a function $f(t)$, for $t \geq 0$ is defined by $\int_{0}^{\infty} f(t) e^{-st} dt$. How to avoid looking at this definition as "magical"? How to somehow discover it from more basic definitions?
What is also very interesting is that the Laplace transform is nothing else but the continous version of power series - see this insighful video lecture from MIT:
I'd always understood the motivation to be that the Fourier transform gives you a function that can be analytically continued, and that analytically continuing it gives you the Laplace transform. Many of the "magical" properties of the Laplace transform therefore follow from similar properties of the Fourier transform, but you get some extra ones as well because you have the theory of analytic functions to draw on.
This answer is not exactly an answer to the original question, but this is for the benefit of MO user vonjd who wanted to know more details about the similarities between solving differential equations through Laplace transforms and solving recurrence relations using generating functions.
Since I was going to write it anyway, I figured I might as well post it here for anyone interested.
I will do an example of each, and this should be enough to show the similarities. In each case, we have a linear equation with constant coefficients; this is where both methods really shine, although they both can handle some variable coefficients more or less gracefully. Ultimately, the biggest challenge is to apply the inverse transform: always possible in the linear case, not so easy otherwise.
Differential Case
Take the function $y(t)=2e^{3t}-5e^{2t}$. It is a solution of the IVP: \begin{equation} y''-5y'+6y=0; \qquad y(0)=-3,\ y'(0)=-4. \end{equation} If we apply the Laplace transform to the equation, letting $Y(s)$ denote the transform of $y(t)$, we get $$ s^2Y(s)-sy(0)-y'(0)-5[sY(s)-y(0)]+6Y(s)=0.$$ Substitute the values of $y(0)$ and $y'(0)$, and solve to obtain: $$ Y(s)=\frac{11-3 s}{s^2-5s+6};$$ and apply partial fractions to get: $$ Y(s)= \frac{2}{s-3}+\frac{-5}{s-2}.$$ This is where you exclaim: "Wait a second! I recognize this, since it's well known that $$\mathcal{L}[e^{at}]= \frac{1}{s-a}$$ for all $a$, then by linearity we recognize the function that I started from.
Recurrence case
Let $(a_n)$ be the sequence defined for all $n\geq 0$ by $a_n=2(3^n)-5(2^n)$. It is a solution of the IVP: \begin{equation} a_{n+2}-5a_{n+1}+6a_n=0 \qquad a_0=-3,\ a_1=-4. \end{equation} Define the generating function $A(x)$ to be: $$ A(x)=\sum_{n=0}^{\infty} a_n\; x^n. $$ Multiplying each line of the recurrence by $x^{n+2}$ gives: $$ a_{n+2}\; x^{n+2}-5a_{n+1}\; x^{n+2}+6a_n\; x^{n+2}=0 $$ You can sum those lines for all $n\geq 0$, do a small change of index in each sum, and factor out relevant powers of $x$ to get $$ \sum_{n=2}^{\infty} a_n\; x^n-5x \sum_{n=1}^{\infty} a_n\; x^n+6x^2 \sum_{n=0}^{\infty} a_n\; x^n=0.$$ Or in other terms: $$ A(x)-a_1x-a_0-5x[A(x)-a_0]+6x^2A(x)=0.$$ Substituting $a_0$ and $a_1$ and solving for $A(x)$ then gives, with partial fractions: $$ A(x)=\frac{11 x-3}{6 x^2-5 x+1}=\frac{2}{1-3 x}+\frac{-5}{1-2 x}$$
Looks familiar? It should! If you substitute $x=1/s$, you will recover $sY(s)$ from the differential example.
For generating functions, the key fact we need here is the sum of geometric series: $$ \sum_{n=0}^{\infty} (ax)^n=\frac{1}{1-ax}.$$ Thus, by linearity again, we recognize the sequence we started from in the expression for $A(x)$.
Closing Remarks
In both theories, there is the notion of characteristic polynomial of a linear equation with constant coefficients. This polynomial ends up being the denominator of the Laplace transform, and the reversed polynomial $x^dp(1/x)$ is the denominator of the generating function. In both cases, multiple roots are very well managed by the theories and explain very naturally the appearances of otherwise "magical" solutions of the type $te^{\lambda t}$ or $n(r^n)$.
The biggest mystery to me is the historical perspective: did one technique pre-date the other, and were the connections actively exploited, or did both techniques develop independently for a while before the similarities were noticed?
Well, the Laplace transform (when you do the integral from -infinity to infinity) is related to the Fourier transform via a factor of -2ipi in the argument. And the Fourier transform is understandable in the abstract framework of Pontryagin Duality.
Basically, what physicists call the "time domain" and the "s-domain" of Fourier transforms are in fact a pair of locally compact abelian groups which are "dual" to each other (in a way similar to how a finite-dimensional vector space and its "dual" space are dual to each other). Check out wikipedia if you want to find out more about this:
You can think of $\int_{-\infty}^{+\infty} f(t) g(t;s) dt$ as a decomposition of $f(t)$ in terms of the basis functions $g(t)$.
There are several nice things about choosing $g(t;s) = e^{-st}$ as the set of basis functions to use, the prime one being that $\frac{dg(t;s)}{ds} = -se^{-st}$, which is a neat property if you're dealing with derivatives.
This paper is a gem in showing the general idea behind the Laplace transform:
Discovering the Laplace Transform in Undergraduate Differential
The key hypothesis is that that solutions to differential equations are combinations of exponential functions. The Laplace transform is a means of extracting the coefficients and exponents (and therefore the free parameters).
Highly recommended!
Even if we don'y use Laplace Transform as often as Fourier Transform, it is definitely a more subtle tool. The reason is that the FT analyses only functions $f:{\mathbb R}\rightarrow X$ that decay at $\pm\infty$. At best, $f$ can be a temperate distribution, and this means that $f$ and its derivatives grow slowly at infty; but let's think about functions. The LT instead deals with functions $f:(0,+\infty)\rightarrow X$ (the domain may be $(-\infty,0)$ as well, but not their union), whose growth at infinity is moderate (at most exponential). Then the transformed function $\hat f$ is defined and holomorphic on a half-space $H$. This gives us the possibility of employing the tools of complex analysis. Also, $\hat f$ contains a lot of redundancy. Let me give an example (which applies to Dirichlet series as well): it may happen that $\hat f$ has a pole at some $z_0$, a point boundary of $H$. I mean that $\hat f$ has a meromorphic extension in a slightly bigger half-space than $H$. Then the residue calculus gives us an information about the asymptotics of $f$ at $+\infty$. This applies to the Prime Number Theorem and to the Theorem of Arithmetic Progression.
The FT and LT are widely used in Partial Differential Equations. Fourier transform is efficient for linear, constant coefficients, Cauchy problems. By this, I mean that the physical domain is ${\mathbb R}^d$, and there is a time variable $t$. Think of the Heat, Wave or Schroedinger equations. Then you apply Fourier to the space variables and receive a linear ODE in $$\frac{d\hat u}{dt}=M(\xi)\hat u(t,\xi),$$ which you analyse easily.
Once the domain has a boundary, you need the Laplace transform, because you cannot get such a simple object as an ODE. At best, you reduce your problem to a linear PDE in $(t,x_d)$, where $x_d$ is the coordinate normal to the boundary. This PDE is parametrized by the Fourier variable $\eta$ associated with the coordinates that are tangent to the boundary. In addition, you have a boundary condition at $x_d=0$, and an initial data at $t=0$. The well-posedness for $t>0$ must then be attacked through a Laplace transform in time (one could do that in the case of the Cauchy problem as well, but this is not so essential). The key words in the theory are incoming modes and Lopatinskii condition.
For the interested readers, see my book in collaboration with S. Benzoni-Gavage, The Hyperbolic Initial-Boundary Value Problem, Oxford Univ. Press (2007).
"Laplace transform is nothing else but the continous version of power series"
In fact, Laplace transform origins are in Heaviside's operational calculus, i.e., the theory of formal power series.
There is in fact a very good paper of 2011 which addresses this question exactly:
The Laplace Transform: Motivating the Definition
protected by Ryan Budney May 17 '14 at 7:29
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text: Close Tweet0 Share0 Comment0 Share0 Share0 Stumble It0 Print0 More Beyond the Baseline Federer releases 2013 ATP schedule: Miami, Basel missing by Courtney Nguyen Twitter Email Posted: Mon Nov. 19, 2012 Roger Federer released his 2013 schedule and will skip the Sony Open in Miami, an ATP Masters event. (Clive Brunskill/Getty Images)Roger Federer posted his 2013 schedule on his official website and there's one significant tournament missing: the Sony Open in Miami, an ATP Masters 1000 event.Beginning next year, Federer will enjoy complete exemption from the ATP World Tour Masters 1000 player commitment, meaning he can choose to skip as many mandatory Masters tournaments as he wants. The exemption stems from Rule 1.08 in the ATP rulebook, which reduces a player's Masters commitment by one tournament for reaching each of the following milestones:1) Has played 600 career matches.2) Has 12 years of service.3) Is 31 years of age.Once a player reaches all three milestones, he has complete exemption from the Masters commitments. That's where Federer finds himself next year, and why he can skip those events without penalty.On his website, Federer lists his 14-event 2013 schedule. Of course all the Grand Slams are there, but Federer will not play the hard-court Miami event and, as of now, will not play his hometown event in Basel. Here's the Swiss champion's complete schedule:Australian Open, MelbourneABN AMRO World Tennis Tournament, RotterdamDubai Duty Free Tennis Championships, DubaiBNP Paribas Open, Indian WellsMutua Madrid Open, MadridInternazionali BNL d'Italia, RomeRoland Garros, ParisGerry Weber Open, HalleWimbledonRogers Cup, MontrealWestern & Southern Open, CincinnatiU.S. Open, New YorkShanghai Rolex Masters, ShanghaiBNP Masters , ParisWhile his decision to skip Basel is understandable given recent reports of a personal dispute with the tournament director, he still has plenty of time to make up his mind about that event as the year (and negotiations) progresses. (There have already been reports that he'll reach an agreement in time to play Basel next year.)So the only real surprise is Federer's decision to skip Miami. From a practical point of view it makes sense, as Federer will play a fairly heavy spring schedule, with the Australian Open, Davis Cup (potentially), Rotterdam, Dubai and then Indian Wells. Skipping Miami would give him a six-week break until his clay season begins in Madrid. And given his split with IMG this year, he has no vested interest in supporting the IMG-backed tournament. Federer also chose to skip the Abu Dhabi exhibition in December, another IMG-organized event, for the first time since its inception in 2009. But it leaves an interesting potential dynamic between Indian Wells and Miami, the two biggest North American spring tournaments. Indian Wells has long suffered from the Williams sisters' blanket refusal to play after an alleged racial incident in 2001, while Miami has been able to boast a full field for both the men and women. Now the tournament could suffer the absence of Federer, the biggest draw in the sport, at a time when the tournament is trying desperately to outdo the Larry Ellison-backed Indian Wells. More Beyond the Baseline

subset: commoncrawl


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JUNCTION CITY, Kan. (WIBW) -- A local Olympian is getting ready to make his way back home from the London Games. The Junction City native has stunned the international track scene with his rapid journey from a virtual unknown to an elite athlete.
For Betty Young, it's hard not to get emotional when she thinks about her son, Isiah, being on the track with the fastest men in the world at the Olympics.
"Since day one, he's always tried to do things to make me proud and every time I think I'm as proud as I can get, he does something else to make me even more proud. This experience has been, I mean, words cannot describe how proud I am of him. He's my Olympic hero. That's what I've been telling everybody. He's my Olympic hero no matter how he did. He tried his best and that's all I expected," she told 13 News.
The 22-year-old sprinter from Junction City placed third in Round 1 of the Men's 200 meter and 8th in the semifinals this week.
It's Young's rise to the stop of his sport that's been making headlines because, like his running, it was fast. His career started only four years ago on the track at Junction City High School when he was a senior.
Forika and Fawn McDougald helped discover Isiah Young, noticing his raw talent. They helped coach him to greatness.
"He went on to be junior college All American and won the Southeastern conference, which he kind of followed in our footsteps because we both have conference titles. He followed that up and now, what he accomplished in the Olympic Games in four years- it's unheard of. Unheard of! We may not see something like this ever again," Forika McDougald said.
"It's like watching one of my children run. That's how I think of him, as one of my children and so I was the proud mom, surrogate mom as you would say," Fawn McDougald added.
Young will be a senior at Ole Miss in the fall and his family and coaches say his star will only continue to rise.
"This is just the beginning! In 2016, I'm calling it! He's going to take it so I'm saying it now," his mother said.
Betty Young and the McDougalds could not make it to London to see Young race in his first Olympics but they do hope to be there at the 2016 Games, they told 13 News.


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Just recently started playing Dominion. The rules say you can count remaining cards, but not in your deck or discard. I was wondering if it would be legal to keep tally marks on paper for specific card draws - both for my cards and an opponents. This might need to just be a house rule, unless it is specifically forbidden. And of course you still might miss something, throwing your count off.
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I think you missed something in the rules:
(I typed this from my copy of the Intrigue rules; it looks like it says the same thing in the original rules - it's in the Additional Rules section in both.)
So... you can do exactly what those rules say. If you want to do anything else, that's up to you and the people you play with. It seems pretty clear that keeping track of your discard pile on a sheet of paper is equivalent to counting it. Donald X would seem to agree, saying that using a notebook to keep a tally of score is not officially endorsed by the rules. (Thanks to Rob Renaud for providing that link!)
In many games but especially in a game like Dominion - where the play is meant to be fast and furious - it's really against the spirit of the game to be doing so much to keep track of everything.
There are other great games out there that are "thinkier" (Race for the Galaxy, for one) but Dominion is meant to be low overhead - enjoy it for what it is.


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Staying hydrated in pregnancy can be a challenge. Because of the hormonal changes taking place, some of the fluid you take in leaks into your body tissues, rather than staying within the bloodstream.
It's difficult to recommend an exact amount of fluid that should be drunk to keep you hydrated, since this depends on many factors, such as the foods you eat (some naturally contain water), your size, the amount you exercise, and the heat and humidity in the environment. Therefore, you need to listen to your own body to determine if you're adequately hydrated. One of the best ways to do this is to look at your urine. If it's clear to light yellow, you're adequately hydrated. If it's bright yellow or orange, you're likely to be dehydrated.
Drinking plenty of water is important. Sometimes, though, if you are nauseous, or just plain tired of drinking water, you may want to try other options for hydration, such as drinking juice or eating more fruit. Remember that caffeinated beverages, such as coffee, are not hydrating; caffeine has a diuretic effect, which means that you will want to urinate more often.
In the second and third trimester, dehydration in pregnancy can lead to premature contractions. This is because an anti-diuretic hormone is produced to help your body hold on to water. This hormone acts a lot like oxytocin, the hormone that triggers labor, causing contractions. Staying hydrated will prevent this from happening.
One great way to stay hydrated is to eat fruit. Many fruits are very high in water, especially melons, grapes, and strawberries. The water in fruit is very well absorbed in your body, because it comes partnered with sugar, which helps the water stay in your bloodstream.
In addition, fruit is highly nutritious and contains many of the vitamins and electrolytes that your body needs to stay in balance.
You may be experiencing some back pain and discomfort as your hormones begin to soften your ligaments. This means that your joints are less stable than usual, and injury is more likely.
Lifting your toddler will not harm your baby, but it may cause you discomfort, and you may be more likely to lose your balance. Ask your toddler to climb onto a chair so that you don't need to lift from bending position. To lift from floor level, squat down and use your legs to bear the weight. Avoid bending, which strains your back. Encourage your toddler to get onto your lap for a hug.
Excerpted from Pregnancy Day by Day.
Copyright © 2008 Dorling Kindersley Limited.
Buy this book now!
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Stock up on Ateco tips so you can decorate cakes, cookies, brownies, and pastries with intricate designs. These Ateco decorating tips come in various sizes and styles. Choose from petite tips for very fine decorating, or use large ones to pipe whipped cream on cakes and even plate mashed potatoes! We offer tips with plain, open star, closed star, and rose leaf designs for the greatest variety of options.
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Shop for Stanley Cup® Collectibles, Jewelry, Gifts and More at The Bradford Exchange Online
Do you love hockey? Are you a big fan of the NHL® and all of its thrilling no-holds-barred action on the ice? Then we are glad you "skated" on over to The Bradford Exchange Online. We are proud to offer a compelling roster of unique hockey collectibles, NHL® jewelry, gifts and more, just in time for the 2012 Stanley Cup® season. Featuring fine jewelry and collectibles, from Stanley Cup® rings to NHL® Christmas ornaments, (including a Stanley Cup® trophy figurine), we are excited to provide you with lasting ways to honor some of your favorite teams.
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I have this false prove which I can't find the problem in. Trying to find the field extension degree $[E:\mathbb{Q}]$ where $E$ is the splitting field of the polynomial $f(x)=x^3-5$ over $\mathbb{Q}$.
My false proof is: The roots of $f$ in E are $a,b,c$, we don't need to state them precisely at the moment. Since $f$ is irreducible over $\mathbb{Q}$, $f(x)=irr(a,\mathbb{Q})=irr(b,\mathbb{Q})=irr(c,\mathbb{Q})$, and hence $\mathbb{Q}/(x^3-5) \cong \mathbb{Q}(a) \cong \mathbb{Q}(b) \cong \mathbb{Q}(c)$, therefore $b,c\in \mathbb{Q}(a)$, therefore $E=\mathbb{Q}(a,b,c)=\mathbb{Q}(a)$, therefore $[E:\mathbb{Q}]=3$.
This contradicts several other things, which are the reason I believe this prove is false. Can you spot the not?
Thanks, G.


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What do you think of the following form design which I've prepared?
- there's a progress bar in the top
- on the right side the steps are listed, and every time the current state is indicated by selection
Do you use anything else? Is this sufficient? (in this current case the form is designed for a bank)


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According to wikipedia, progerin is activated in senescent cells. The protein itself is known to be the cause of a rare affliction 'progeria' - a disease marked by accelerated aging of the body. This disease is not accompanied by neurodegeneration.
- Is progerin the key factor in the aging process?
- If yes, could inhibition of progerin formation control the rate at which a body ages?


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Originally Posted by mayjune
btw shabbir why in the poll
Men is Men and women as Women
lol ...?
Originally Posted by SaswatPadhi
LOL @ MayJune
Men is shown as Men and Women as Women, because you voted for Men.
The option you vote for, is italicized !
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One of the reasons why programmers prefer SVN over CVS is the former allows atomic commits ? What does this mean ?
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It means that when you do a commit to the version control system either everything you want to commit goes in, OR nothing does.
In CVS, when you try to commit it's possible for the commit to succeed on several files, then fail on several others (because they've changed). This leaves the repository in an unfortunate state because half of your commit isn't there, and it's likely that you've left things in a state where they won't compile or worse. Now you've got to hurry up and integrate whatever changes so that you can commit the other files before someone else needs to update and gets your broken set of changes.
In SVN this won't happen - SVN will either commit everything you've changed, or it will fail the whole changeset. Thus, you'll never leave the repository in a broken state due to commit issues.
This is explained eg in Bye-bye CVS. I've been Subverted article written by Andy Lester:
The fact that CVS forces programmer to fix the merge immediately is as counter-productive as it gets. Compared to that, an option to delay / cancel / carefully merge changes is a substantial benefit.
Other benefits of SVN over CVS explained in above article are:
It means that all changes to all files are committed in a single transaction, so either all succeed or none.
This means that you are less likely to get partial edits checked in to the repository which cause builds to fail. You can still get people forgetting to check in all the relevant files, but that's a process issue rather than a problem with the versioning system.


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Hello WOW
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Note: we only give a property a rating once it has received a minimum of 3 reviews.
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- 10 Oct 2014 Anonymous Indonesia


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"Excellent quality at great price" (E7948)
"I am extremely satisfied with the Alleson 54MMR adult reversible basketball jerseys. They are a quality product that looks nice and is very durable." (E17233)
"The customer service was awesome the prices were the best I found and my boys look amazing in their jerseys." (E45988)
Epic Sports
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Hybrid View
24 Dec 2012 1:32 AM #1
Problem in parsing XML packaged with SOAP Envelope
I'm using ExtJS 4.1.1 ,and I quoted and override the Soap Proxy in 4.1.3 .Now I can send Soap request to and receive response from my SOAP Web Service, but I cannot parse the XML received from the service. My XML is extremely like the XML in the example on this site http://docs.sencha.com/ext-js/4-1/#!/guide/soap. But it throws an error : Uncaught Ext.DomQuery.compile(): Error parsing selector. Parsing failed at "|Body" .Can anyone help me please?
Last edited by panbayi; 24 Dec 2012 at 5:57 PM. Reason: change
26 Dec 2012 11:26 AM #2
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8 Jan 2013 1:28 AM #3
Thank you for your concern.It raises the error because the XTemplate.js in 4.1.1 is different from 4.1.3, so I just need to copy it.
Thank you again for you reply!


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10 Fun & Cheap Halloween Candy Alternatives
3 of 11
Halloween-Themed School Supplies
With the school year still fresh, kids can't get enough of cool new school supplies. Get them in the spooky spirit with a Halloween-themed pencil, pen, ruler, or fancy eraser. Not only are these practical treats to hand out, but they are cheaper than candy!
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I am writing a proposal for my PhD. In the proposal I have included a chapter titled "Actuator Design". Within that same chapter, can I include a section with the same name as that chapter, meaning the very same "Actuator Design" as I've already used?
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You can include whatever sections you like; the real question is whether your advisor or committee will approve what you write. If the structure is made more logical, organized, and clear by having a section called "Actuator Design" within a chapter called "Actuator Design", then go ahead and use such a section.
There are cases where structure would not be improved by such a section: for example, if the section were at the immediate beginning of the chapter and were introductory and general. In a case like that, dispense with the "Actuator Design" section name, and present its information at the chapter level. Then add section headings as necessary following that introduction.
You also might want to rename the chapter or the section. If "Actuator Design" is only a section of a chapter, then the chapter must actually cover more topics than "Actuator Design", or the section must cover less. For example, if your "Actuator Design" chapter has two sections, called "Actuator Design – Overview" and "Actuator Design – Details", perhaps just rename the sections to "Overview" and "Details".
Yes you can.
But I'd like to add, you'd need to think and question why you would have a Chapter Head and a Section Head as the same name.
Normal practice would be to use chapter heads as a generic title as to what that particular chapter contains. Section heads would normally go into even more specific detail about the contents of the chapter.
Chapter Title - Actuator Design
Section Heading - Design Parameters, Design Specifications, Design limiting factors, and so on.
It's a poor style - why make it a section while the chapter should contain it, what are other contents of the chapter if one section covers its whole title.
But you can give it a subtitle:
If your chapter is to contain only one section, which covers the entire subject of the chapter, don't make any section and start writing the content directly under the chapter level.


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Today in Tweet Beat, celebs like Rob Zombie, Elizabeth Banks, and Roger Ebert mourn the death of graphic novelist Harvey Pekar. Plus, William Shatner is hanging out in a cardboard box on the streets of New York.
RIP Harvey Pekar. I interviewed him about 22 years ago. He will be missed. An American classic. Best comics ever.
Harvey Pekar. I guess he's finally satisfied. http://twitpic.com/24peur
very sad to hear about harvey pekar.
RIP Harvey Pekar. A hilarious man.
Literally thinking inside the box on the streets of New York while waiting for Kate Mulgrew. My best, Bill http://twitpic.com/24qyf2
Speaking to a dental group next Saturday in Boston. My Hometown.Never did see a dentist on the Enterprise !! LLAP
As long as their are batteries & electrical plugs 4 my toys, what purpose does a man serve other than to bitch? ; )
I just returned from the past, headed to the future
I cant wait until tonights episode of Housewives of New Jersey! counting the hours...also am obessed with Real World: New Orleans.
I've been asked to blog about tonight episode but I haven't seen it. I'm scared. It has to be a real doozie...oye #ThankgodIstayedhome
It's a good thing I was born a girl, otherwise I'd be a drag queen


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Pharmaceutical companies are responding to the high cost of introducing new drugs to market in different ways. For new drugs, companies are examining drug products and their delivery systems far earlier in the design phase than they have in the past to ensure success of the new drug and device combination. At the same time, existing APIs are being repurposed for new therapeutic treatments or delivered using improved formulation and delivery methods that may better resolve the physiological, biochemical, and physicochemical barriers. These shifts have increased the industry's focus on the drug-delivery platform as an enabling technology that can optimize drug efficacy and cost-effectiveness.
Simulation software is one technology that can improve device performance by allowing pharmaceutical companies to virtually model and prototype the delivery of new drugs. Various properties can be examined, including the drug's composition, particle size, flow, andhuman physiology.
Numerical simulation tools, such as finite element analysis (FEA) and computational fluid dynamics (CFD) provide a way to rapidly and economically examine a wide array of drug-delivery technologies. Early in the design cycle, numerical simulation identifies designs and operational conditions that might not meet therapeutic requirements, thereby allowing companies to address these and to develop accurate, safe, and effective design before the first prototype is developed. Later on, models can be constructed to simulate the actual drug-delivery process to humans. Although these advanced studies entail more upfront effort, especially if validation is required, they provide significant advantages over experimentally driven develoment processes. Therefore, they can decrease the chance of design changes after the product enters animal or clinical trials. This article describes these simulation technologies and related case studies.Computation fluid dynamics tools
Because of the fluidic nature of drug delivery, CFD tools are commonly used to understand and optimize the delivery process. CFD takes advantage of numerical methods to solve the fundamental equations for fluid flow and heat/mass transfer. The process begins by creating the medical device in a computer aided design (CAD) tool or in other solid modeling software. The next step is to decompose the domain into a computation grid or mesh. Anatomic structures are incorporated as needed using one of two approaches:
Segmentation tools combine the anatomic data with the device, create a mesh, and export the meshed assembly in a format readable by most leading commercial simulation software. The user enters material property data, initial and boundary conditions, and submits the job to the CFD solver. Once the problem is converged, the user visually and quantitatively reports results for fluid flow, density, drug concentration, and other variables. Cut planes and surface plots are the most common way of displaying the results. Alternatively, one can extract point, surface, or volumetric results for quantitative comparisons to experimental or other data.


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The 7 Most Baffling Things Ever Discovered in a Human Body
#3. Concrete Enema
In 1987, a 20-year-old man was admitted to the hospital complaining of rectal pain. X-rays revealed a hard, stony mass. The man admitted it was concrete that his boyfriend had poured into his ass while they were "fooling around" that had subsequently hardened into the equivalent of a massive concrete shit-brick.
Because nothing says "I love you" like a funnel and quick-drying cement.
The concrete was removed in a perfect cast of the inside of the man's butthole, sort of like those wax hands you can have made at carnivals.
Like this, only more ass-tastic.
The man was kept in the hospital overnight and discharged the next morning in perfect condition, having somehow managed to not injure himself in the slightest during the whole bout of concrete friskiness. Interestingly, the cement had hardened around another object that was removed along with the cast -- a ping-pong ball, fully intact. Presumably the doctors then carefully excavated the cast like paleontologists, searching for errant hamster bones.
This is what the inside of an asshole looks like.
#2. A Condom
A 27-year-old woman was admitted to a hospital in India after experiencing six grueling months of coughing, spitting up phlegm and running a fever. Despite four months of antibiotics and tuberculosis treatments, her health was not improving. The doctors then decided to do a videobronchoscopy (when they use those tiny cameras attached to tubes) to examine her airway. They found a strange baglike structure in her bronchus, which you may notice is not generally a symptom associated with bronchial infections. Utilizing the most advanced techniques of modern medicine, the doctors reached down her throat with a pair of forceps and pulled out the tattered remains of a condom.
Worst water balloon fight ever?
Now it was time to conduct a "detailed retrospective history," which is apparently what doctors call their job when the truth is too embarrassing and they want to make it seem like they're doing rad CSI style lab work. Eventually, they deduced that she had accidently inhaled the condom while giving a blow job, though not before some pretty strenuous arguments over whether that was even possible.
Medical records don't indicate how the diagnosis was conveyed to the patient. Did they compliment her on practicing safe sex before outlining a medical treatment plan for giving less enthusiastic blow jobs? Did they simply sit there looking impressed?
"OK seriously, how drunk were you? I've got a bet with the interns."
WARNING: This next entry contains disturbing images.
#1. Teratomas
Teratoma tumors are tumors that often contain hair, teeth and bones, and sometimes even eyes, hands or torsos. You may have heard that they're just a bullshit urban legend, but we assure you they are very real, and they look like the aliens from John Carpenter's The Thing.
Yes, those are freaking teeth.
A baby in Colorado Springs, Colo., was born with a microscopic tumor in his brain, causing doctors to take him into surgery even though he was only three days old. There, they removed the growth and found that it contained one fully formed foot, another partial foot and the beginnings of a hand and a thigh, leading us to wonder if a Smurf-sized twin would've burst through his skull like the Kool-Aid man had the tumor been left unattended.
Another infant, born in Korea, had two separate growths, one containing an eye, a trachea, various internal organs and even a goddamn brain. The other had bones, vertebrae, and intestines, and both were covered in a membrane that clearly contained an umbilical cord. Again, it's difficult to get the twin-bursting image out of our minds when a baby is born with 90 percent of another human being attached to it in two separate lumps.
They don't show up just in babies, either. A 25-year-old Japanese woman had to have one removed from her ovary that contained a lump holding a head, one fully formed eye and numerous internal organs.
We know. The word "Japanese" had us expecting a sentient tentacle tumor too.
Why, nature? You just took every beautiful, complex part of life, then stuffed it into a tiny meat sack and put it in our bodies. It's like finding a cosplayer with giant boobs, then crumpling her up into a bloody heap and shoving her in an ice cream cake.
They've even been known to show up on men. Specifically, the testes. So for all our male readers out there, it turns out that on the spectrum of "worst things to find attached to your junk," not even the lady who inhaled a condom tops the list in the category of "things with teeth."
Yeah, suddenly that big fancy doctor salary doesn't seem so impressive.
For more from Fero, check out her blog or be one of the thousands of assholes who follow her on Twitter.
We've got stuff more horrifying than that in our new book. So pick it up!
We're not finished giving you nightmares yet. Be sure to check out 19 Unintentionally Terrifying Children's Album Covers and The 7 Most Horrifying Museums on Earth.
And stop by Linkstorm to cleanse your mind (and your mind).
And don't forget to follow us on Facebook and Twitter to get sexy, sexy jokes sent straight to your news feed.
Do you have an idea in mind that would make a great article? Then sign up for our writers workshop! Do you possess expert skills in image creation and manipulation? Mediocre? Even rudimentary? Are you frightened by MS Paint and simply have a funny idea? You can create an infograpic and you could be on the front page of Cracked.com tomorrow!


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JUNCTION CITY, Kan. (WIBW) -- The Kansas Bureau of Investigations has been called in to investigate an officer-involved shooting in Junction City after officials say a man pulled a gun on deputies from the Geary County Sheriff's Department outside of a nightclub early Sunday.
The man at the center of the shooting as been identified as Stefon Butler, 25, from Junction City.
Geary County Undersheriff Tony Wolf released the following information on the shooting to WIBW Sunday:
"On Sunday May 13, 2012 at approximately 2:00 AM, Geary County Sheriff's Department Deputies were assisting Junction City Police Department Officers at 713 S. Washington St. (Club Eve) with monitoring the parking lot at closing. During this time, a disturbance broke out and one subject involved fled behind the building where Deputies from the Sheriff's Department were. This subject produced a firearm in an aggressive manner; the subject was shot one time, and collapsed. Junction City EMS responded and transported the subject to Geary Community Hospital where he was airlifted by Life Star to Stormont Vail in Topeka with very serious injuries. Kansas Bureau of Investigations was contacted to handle the investigation."
Butler is listed in stable condition at Stormont-Vail Hospital in Topeka.
Undersheriff Wolf said in an updated news release Monday: "Once the KBI finishes their investigation, the case will be presented to the Geary County Attorney for his review."
No other details are being released at this time. No other injuries were reported.
According to the Kansas Department of Corrections' website, Stefon Butler was convicted in Geary County in 2004 on one count of Possession With Intent to Sell Drugs, Depressants,Stimulants, Hallucinogenics, etc. The site indicates that he was discharged in 2008.


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Hybrid View
12 Nov 2012 8:32 AM #1
No charts has all the charts?
Sencha Cmd v18.104.22.168
Mac OSX 10.6
Took this off the sencha blog post:
sencha compile -classpath=ext4/src \ exclude -namespace Ext.chart and \ concat -out ext-all-no-charts-dev.js and \ -option debug:false \ concat -out ext-all-no-charts-debug.js and \ concat -yui -out ext-all-no-charts.js
Related posts:
One guy says if he excludes "debug" he can make it work, but I had no success.
Has anyone got a no-charts version, can you share the working command?
28 Nov 2012 4:09 PM #2
This is the first example given in the docs for the Sencha Compiler Reference.
It runs fine. I have nothing to debug.
How much blood do I need to donate ?
Can I buy a vowel?
Anyone know how to exclude charts?


text:
For instance, biologists these days like to say that the word "dinosaur" is inclusive of modern birds, since birds are descended from dinosaurs. This is consistant with biologists' tendency to categorize things monophyletically -- that is, if it is descended from something, it "is" that something. A bird is descended from a dinosaur, so it must be a dinosaur.
Linguists (such as those employed by dictionaries e.g. Webster and Oxford) tend to be more pragmatic -- concerned more about communication and usefulness rather than strictly adhering to monophyletic categories. They consider "dinosaur" to only refer to those animals that lived in the mesozoic period....that is, they explicitly exclude modern birds from the definition, because when most people use the term "dinosaur," they are not talking about birds.
This is similar to the way we exclude tetrapods (amphibians, reptiles and mammals) from the definition of "fish", even though tetrapods are descended from fish. That is, "fish" is, by definition, a paraphyletic category. Other examples are "monkey" and "ape", which, by definition, are paraphyletic and therefore exclude humans.
So who is the authority on the definition of these words? And if biologists are, isn't it being inconsistant to define the word "fish" to exclude a subset of its decendants, while refusing to do the same with the word "dinosaur"?


text:
I'm looking for a keyboard controlled window sizing utility similar to ShiftIt on Mac OS X: https://github.com/fikovnik/ShiftIt
I assume you want a feature that allows you to tile your windows like ShiftIt allows via Cmd+Shift+Left and Cmd+Shift+Right
As your question seems to be targeted at Gnome you might want to try BlueTile that seems to specifically target the Gnome-Desktop.
Apart from that I think the new Unity-Desktop from Canonical allows similar features via Ctrl+Shift+Left, Ctrl+Shift+Right and the NumPad keys (in 12.04 at least you can press the Windows key and see an overview over the available shortcuts).
And - even though I have never used it the Grid-Plugin for Compiz might also fit your needs.
Apart from that there are a ton of window managers that can do all the tiling for you, but they may require initial setup and be very different to use than the more common ones. Some examples in this camp include:
GNOME already has some keyboard window manipulation available by default. Take a look at https://wiki.gnome.org/Design/OS/KeyboardShortcuts
Otherwise, you may want to try using another window manager with more window control options.
Not direct answer (see mine comment), but it seems lots of X window newcomers do not know that Alt_MouseLeftBtn allows dragging windows around the screen and Alt_MouseRightBtn — resizing them (something that Mac OS X GUI
I usually prefer Fluxbox and it has some key-binding for changing window geom as well.


text:
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US Open Championship - MondayMon, June 10, 2013 - 9:00 AMMerion Golf Club in Ardmore, PA
We are sorry, the date for this event has already passed. This event took place on 6/10/2013. Click here to view upcoming events for US Open Championship.
Still unsure? Check out our user reviews for:
Have a question? Need help? Call us at 800.477.5285


text:
Former Massachusetts Gov. Mitt Romney gestures while delivering remarks at the Heritage Foundation in Washington, Monday, June 1, 2009. (AP Photo/Manuel Balce Ceneta)
FROM NPR NEWS -- Mitt Romney clinched the Republican presidential nomination Tuesday evening with a win in the Texas primary, a triumph of endurance for a candidate who fought hard to win over skeptical conservative voters he must now fire up for the campaign against President Obama.
According to the Associated Press count, Romney surpassed the 1,144 delegates needed to win the nomination by winning at least 88 delegates in the Texas primary.
Romney, who came up short in the Republican presidential race four years ago, outlasted a carousel of Republican rivals who dropped out of the state-by-state primary contest. None of his former rivals actively campaigned in Texas.
The former Massachusetts governor has reached the nomination milestone with a steady message of concern about the U.S. economy, a campaign organization that dwarfed those of his Republican foes and a fundraising operation second only to that of Obama, his Democratic opponent in the general election.
"I am honored that Americans across the country have given their support to my candidacy and I am humbled to have won enough delegates to become the Republican Party's 2012 presidential nominee," Romney said in a statement.
"Our party has come together with the goal of putting the failures of the last three and a half years behind us," Romney said. "I have no illusions about the difficulties of the task before us. But whatever challenges lie ahead, we will settle for nothing less than getting America back on the path to full employment and prosperity."
In Obama, he will face a well-funded candidate with a proven campaign team in an election that will be heavily influenced by the economy.
One issue that has drawn backing from some of the most conservative Republicans the question of Obama's citizenship resurfaced again on Tuesday.
Romney spent Tuesday evening at a Las Vegas fundraiser with celebrity real estate mogul Donald Trump, who has been renewing discredited suggestions that Obama wasn't born in the United States. Romney says he believes Obama was born in the U.S. but has yet to condemn Trump's repeated insinuations to the contrary.
The Obama campaign released a video Tuesday criticizing Romney's unwillingness to stand up to Trump and the more extreme elements in his party.
"If Mitt Romney lacks the backbone to stand up to a charlatan like Donald Trump because he's so concerned about lining his campaign's pockets, what does that say about the kind of president he would be?" Obama's deputy campaign manager, Stephanie Cutter, said in a statement.
Asked Monday about Trump's contentions, Romney said: "I don't agree with all the people who support me. And my guess is they don't all agree with everything I believe in." He added: "But I need to get 50.1 percent or more. And I'm appreciative to have the help of a lot of good people."
Trump told CNN in an interview Tuesday that he and Romney talk about other issues jobs, China, oil and more and not about the place of Obama's birth or the validity of his birth certificate. Asked how he viewed Romney's position that the president was indeed born in the U.S., Trump said: "He's entitled to his opinion, and I think that's wonderful. I don't happen to share that opinion and that's wonderful also."
Republicans won't officially nominate Romney until late August at the Republican National Convention in Tampa, Florida.
He won at least 88 delegates in Texas with 64 left to be decided, according to early returns. The 152 delegates in Texas are awarded in proportion to the statewide vote. Romney now has 1,174 delegates.
Texas Republicans also voted in a Senate primary to choose a candidate to run for the seat being vacated by Sen. Kay Bailey Hutchison. The party establishment choice, Lt. Gov. David Dewhurst, led the insurgent candidate, state Solicitor General Ted Cruz, and Dallas Mayor Tom Leppert in early returns.
If no one gets more than 50 percent of the vote, the top two finishers will go to a runoff in July. The nominee will be strongly favored to win in November in heavily Republican Texas.
Romney, 65, is clinching the presidential nomination later in the calendar than any recent Republican candidate but not quite as late as Obama in 2008. Obama clinched the Democratic nomination on June 3, 2008, at the end of an epic primary battle with Hillary Rodham Clinton. Four years ago, John McCain reached the threshold on March 4, after Romney had dropped out of the race about a month earlier.
Several other Republican contenders including Newt Gingrich, a former speaker of the U.S. House of Representatives, and Rick Santorum, former U.S. Senator from Pennsylvania earlier dropped out of the race as Romney's well-financed campaign gained momentum.
Romney has been in general-election mode for weeks, raising money and focusing on Obama, largely ignoring the primaries since his competitors dropped out or stopped campaigning.
Libertarian-leaning Texas Rep. Ron Paul said on May 14th he would no longer compete in primaries, though his supporters are still working to gain national delegates at state conventions.


text:
News and Updates
Systems & Operations - UM Production Support
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The Production Support Department, also known as Production Control, provides professional, administrative support to the University of Missouri System. Our goal is to ensure the below mission-critical services are performed efficiently and with minimal interruption and cost to the University Of Missouri.
Outlined below are services in which Production Support provides:
- Monitor and schedule PeopleSoft administrative processes for the Student Information Systems, Financial Administration, Human Resources and Hospital. Tidal Enterprise Scheduler is the application used to schedule and coordinate the complex, integrated dependencies required of batch processing system-wide. An average of 55,000 programs process monthly, to ensure the high-volume of administrative data entered daily in PeopleSoft processes efficiently.
- Secure Data transfers execute internally and externally to the University of Missouri utilizing an application called MOVEit Central. MOVEit transfers sensitive data using PGP encryption/decryption, zip operations, command-line applications and has an antivirus integration built in. Additionally this application plays a role in keeping SSN's secure.
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text:
Members of the media who wish to reach students, faculty, staff, or a spokesperson of the College, please email Media Relations or call 802-440-4399.
Bennington College
Office of Communications
One College Drive
Bennington, VT 05201-6003
In celebration of the 200th anniversary of Charles Darwin's birth, biology faculty member Elizabeth Sherman will lecture on Why Darwin Matters at the Northshire Bookstore in Manchester, Vermont on Friday, March 27, at 7 pm. This event is free and open to the public.
"Why should we care that roughly half of Americans don't accept evolution?" Sherman asks. "If people can deny evolution, so well supported by scientific evidence and so widely accepted by the professional scientific community, then they can deny any scientific findings they like."
Known for her extensive work in amphibian behavior, Sherman has been published in Herpetological Review, Journal of Comparative Physiology, American Zoologist, Comparative Biochemistry and Physiology, and Journal of Thermal Biology.
For more information on her upcoming lecture visit northshire.com.


text:
19 Oct 2010 11:12 AM #1
[OPEN] CheckboxSelectionModel not showing up when using a PagingToolbar
When using both the CheckboxSelectionModel and a PagingToolbar the checkbox does not show up in exported code.
Still does not work after following the recommendation from 104373-FIXED-186-Not-Including-CheckboxSelectionModel-In-Column-Model by promoting Grid to Class.
Designer 126.96.36.199
with ExtJs 3.3.0
Thanks in advance
19 Dec 2010 10:10 PM #2
- Join Date
- Mar 2007
- Location
- Frederick, MD
- Posts
- 1,747
- Vote Rating
- 7
This is indeed an issue, carrying over into 1.0.3. We'll get this resolved ASAP. Thanks for reporting.
13 Aug 2012 4:22 AM #3
Any luck with this?
Any luck with this issue?
I'm not able to see the checkbox column unless I add the selection model manually to the columns array.
I'm using Ext JS 3.4
Designer: 1.2.3 b54
13 Aug 2012 6:12 PM #4
I'm not sure i follow this one so I can't see if it's still a bug. I did see http://www.sencha.com/forum/showthre...n-Column-Model was mentioned does that help?Phil Strong
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Dr. James E. Keeton, vice chancellor for health affairs and dean of the School of Medicine, will conduct a town hall meeting for School of Medicine faculty from noon-1 p.m. Wednesday, April 17, in room R-153 (lower amphitheatre). Boxed lunches will be provided on a first-come basis.
The presentation will be the first of two town hall meetings Keeton will host for medical school faculty during this calendar year. The next one will take place in the early fall.
The meeting will be videotaped for later playback for those unable to attend in person.
For more information, call 4-1100.


text:
WEIRTON - The Madonna girls basketball team, with only two seniors, opened the season with a big first quarter and coasted to a 53-25 win Monday night over Bishop Donahue at the Bill Barrett Gymnasium.
The Lady Blue Dons (1-0) outscored the Lady Bishops (0-1) 21-6 in the opening stanza with senior Nicolette Sellitti getting 10 of her game-high 15 points. Sophomore Rachel Grubbs chipped in seven points in the blitz. Sellitti was three- for-three from behind the arc in the game and hit two of them in the big first period.
"Many of our players are very young without varsity experience and that's the unknown for us going into the season," said veteran Madonna coach Don Ogden. "I thought our seniors, Sellitti and (Amy) Davis, held things together."
Article Photos
FOR TWO — Madonna's Rachel Grubbs goes up for a jumper against Bishop Donahue Monday in Weirton. The Blue Dons beat the Bishops 53-25.
-- Fred Younce
Ogden got 12 points from promising freshman Monica Bragg, who also swished one through from three-point land.
"Monica got to show some of her potential, and our other freshman starter, Becca Holt, did a good job at point guard," Ogden continued. "The two Grubbs girls, Rachel and Leanne, gave us some good minutes. Yes, we're young, but it is nice to get that first win under our belt."
Rachel Grubbs, who became ill in the second half, finished with eight points. The Blue Dons also got six points each from sophomore Aubrey Platek and freshman Isabella Rosso.
Bishop Donahue coach Don Gillis was quick to complement Madonna.
"We really didn't shoot the ball very well and we had a lot of turnovers," he said. "Last year we shot only 26 percent from the floor and it hasn't changed much this year even though a lot of the girls are seniors. We work on our shooting every day in practice, but we just can't get the shots to go in.
"I thought we hustled up and down the floor and ran our offense pretty well. Madonna's just a fantastic team. We like to play better teams and Madonna is one of them."
The Lady Bishops managed to sink nine field goals with Selena Ghaphery getting four the them. She led the scoring with nine points. Ali Bauer and Kelsey Schau each contributed six points and Kenedee Kleeth chipped in four as only four Bishop Donahue players got into the scoring column.
Madonna cooled off in the second period just matching the six points that the Lady Bishops scored, but came back in the third to score 19 and put the game out of reach.
"I thought that after a good start we got a little sloppy in the second quarter, but we made some adjustments at halftime and did well in the second half," Ogden explained.
The Lady Blue Dons led 27-12 at the half and went into the final stanza with a comfortable 46-19 lead.
Madonna continues at home entertaining Bridgeport Thursday night while the Lady Bishops will have their home opener Saturday against Connotton Valley.
Madonna 53, Bishop Donahue 25
Bishop Donahue 6 6 7 6 - 25
Madonna 21 6 19 7 - 53
BISHOP DONAHUE (0-1): Bauer 2 2-4 6, Ghaphery 4 1-2 9, Schau 2 2-4 6, Kleeth 1 2-2 4. Totals: 9 7-12 25. Rebounds: 17 (Ghaphery, 7); Turnovers: 25.
MADONNA (1-0): Holt 1 1-2 3, Rosso 3 0-0 6, Sellitti 5 2-2 15, Platek 3 0-1 6, Davis 0 1-2 1, Bragg 4 3-4 12, L. Grubbs 0 1-2 1, Lammers 0 1-2 1, R. Grubbs 3 2-4 8. Totals: 19 11-19 53. Three-pointers: Sellitti 3, Bragg 1; Rebounds: 32 (Davis, R. Grubbs, 6 each); Turnovers: 19.


text:
Currently looking at a longish form with a lot of yes/no options presented as radio buttons. Is there any evidence that displaying radio buttons either vertically or horizontally is preferable?
I'm not a fan of horizontal layouts for radio buttons for four big reasons:
I am not aware of the available studies but here are a few thoughts.
Horizontal display seem to be easier to visually scan for all answers since you have "Yes" on one side and "No" on the other. It also I think makes it easier for the user to check all the answers the same way; you just move your cursor down (check, check, check). So I am leaning towards horizontal arrangement.
I agree with Anna Rouben's answer. However, my layout is slightly different...
The goal here is to maximize readability and scannability. And this is the layout I've used for hundreds of questions in the past.
A couple notes...
It should be vertically aligned. Quote from Windows User Experience Interaction Guidelines:
Source: http://msdn.microsoft.com/en-us/library/windows/desktop/aa511488.aspx
Thanks for all the answers. I think my view is now:
I'm not sure how mobile usage would affect this problem but I'm inclined towards vertical as width is typically at more of a premium.
Like @AnnaRouben, I agree that the choices are probably clearer and easier to scan when laid out horizontally. However, I would like to add that you should always allow users to select 'No Answer', otherwise some of your data will be meaningless.
People need the ability to change an incorrect answer back to No Answer if they mistakenly click or do not understand the question, or if neither choice applies to them.
The horizontal is easier to scan since there's a strong visual differentiation between the Yes and the No. It also forces the choice to be more accurate, because the radios are farther apart. But the vertical is easier to fill, since you don't have to zigzag with your mouse, you just move it down in a straight line.
For speed, stack them vertically. For accuracy, lay them out horizontally.
If this will ever be used on a mobile device, a horizontal alignment works better for 2 reasons.
One, you'll need to provide adequate space around each radio button so that users aren't likely to accidentally select the wrong one. I think a horizontal layout with generous space between the radio buttons will look more polished than a vertical layout with generous space between the lines. Likewise people are more likely to gestalt-group a horizontal pair of radio buttons with a good amount of space between them than a vertical pair. You could strengthen the connection between them either way by putting some sort of box around or behind them.
Two, your form will take up much more vertical space if you put the radio buttons on separate lines. That may make it seems like it takes forever for a user to scroll through on a mobile phone.
In a future "Yes/No" will be replaced with "Like", said fb founder (just a joke)
In this case your question: "Do you like drink coffee every day?" Like/Unlike
If it is strictly yes/no you should be using a checkbox. The control exists for a reason, it has both true and false in a single item. Now there is no vertical/horizontal dispute.
I go with vertical.
It seems more readable on horizontal against vertical, maybe; but the difference comes when you resize a lot the screen or you open it on a mobile phone.
When the controls become very small it's easier to select and option with vertical radioButtonList (although it has only 2 options) against horizontal radioButtonList.
If you have multiple yes/no type of question, I would go with the horizontal layout.
It will speed up the process as the user will quickly notice the pattern and click on the right or left choice without even focusing on the actual text beside the radio
Microsoft lot of funny guys ... Vertical presentation is preferable as they write and they put horizontal presentation for the question at the end of the article to know if the topic answer the question... Have a look http://msdn.microsoft.com/en-us/library/windows/desktop/aa511488.aspx
So for me, specially for yes and no radio button horizontal is better. And as it is written try to align them for a list of yes or no to be able to check quickly


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You know, the guy who is advising M for a while during beginning of Skyfall wanting her to resign and such. He sure seemed evil to me and my friends and I had a debate about this... So is he a good guy or bad guy?
I think his character is a red herring: early, he seems like he might be a bad guy who wants to destroy MI6 -- but by the end of the movie, his actions (particularly during the courthouse shooting scene, when he has a chance to shoot good guys but instead shoots bad guys) suggest he is looking out for England's best interests, just like Bond and M.
TL;DR: The filmmakers made him seem bad (not evil, just antagonistic) as a plot device, but later in the movie reveal that he's good by intentions, character, and even qualifications.
"evil" or "Good" is a bit too unanswerable. So let's look at the details and shades and more importantly, how the film-makers change our perceptions of the character.
Mallory or M is the new boss of MI6 and he looks to be good guy. He even tried to save M when she was attacked by Silva in the court room. However he can easily be interpreted as a double agent or an enemy in the upcoming movie. So we will have to wait n see...
No clear cut answer yet, so I found a decent article backing up the notion of Mallory as a good guy, set to become M and support England and 007.
Personally, I think bringing in Fienes to play M is great, which may make the character more involved than previous iterations. Good article, hope you read it.
I don't think there is a definitive answer to this question until we get the future Bond films. However my thoughts were that initially he was involved with MI6 & M to control what she was doing because she had broken rules and the government were questioning these.
Through the events of Skyfall he becomes aware that there is a very good reason why M does things that she does and learns that the rules are there to be broken and/or bent to protect the country therefore this is why Bond respects him and he wants Bond back to work.


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Home > Volvo > Volvo V60 Sports Wagon 2011
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Volvo V60 Sports Wagon 2011
Volvo launches V60 Sports Wagon with coupe-like design combined with dynamic driving characteristics. Stephen Odell, CEO of Volvo Cars, mentions that V60 sports wagon will appeal a S60 buyer looking for some extra space and flexibility along with a sporty design. Volvo V60 Sports Wagon will be available with a variety of diesel and gasoline engines spanning from a mediocre 115 HP DRIVe version to a high-performance turbo charged 304 HP T6 model.


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MSI High and Low
Last Modified: January 24, 2012
What does MSI high/low mean? Which has a better prognosis in colon cancer?
Carolyn Vachani, RN, MSN, AOCN, OncoLink Nurse Educator, responds:
Tumors are identified as MSI-H (i.e. MSI-high), meaning they are MMR deficient (dMMR), or MSI-stable and MSI-low, meaning they are considered MMR proficient (pMMR). Studies have found MSI-H tumors are associated with a better prognosis and is present in approximately 22% of stage II colon tumors (but only 12% of stage III tumors). Several studies have found that patients with stage II MSI-H tumors not only did not derive any benefit from 5-FU adjuvant therapy, but they actually fared worse if they were treated. This was not seen for stage III MSI-H tumors. MS-stable disease, however, may benefit from 5-FU based treatment. Some experts recommend testing for MSI testing as another tool to determine the need for treatment in stage II disease.
Learn more: http://www.oncolink.org/types/article.cfm?c=5&s=11&ss=84&id=9621
This question and answer was part of the OncoLink Brown Bag Chat Series. View the entire Interpreting Test Results transcript.
February 29th is Rare Disease Dayby Christina Bach, MSW, LCSW, OSW-C
February 26, 2016
3 Great Reasons To Have Gratitude On Your Cancer Teamby Marlys Johnson
July 25, 2016


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Are there any testing-related methodologies except TDD/BDD? I see a lot of people who practice their own testing approaches (e. g., see Ayende post), but I don't see any formalization for it, no naming for these approaches.
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closed as too broad by gnat, GlenH7, Dynamic, MichaelT, Robert Harvey Dec 23 '13 at 23:25
There are either too many possible answers, or good answers would be too long for this format. Please add details to narrow the answer set or to isolate an issue that can be answered in a few paragraphs.If this question can be reworded to fit the rules in the help center, please edit the question.
Most test methodologies are integral to the development process they support. For example, in the Waterfall Model, testing follows as feasibility, requirements analysis, system design conformity, Code/Unit testing, Integration/System Testing and finally deployment review/refactoring. It's arguable that this would be called the "Waterfall test" methodology but in effect, that's what it is.
In agile testing, more emphasis is placed on test automation, paired programming (instant test feedback!) and QA within the iterative build cycle.
There are very well defined test methods depending on the software life-cycle needs. Exhaustive lists are available elsewhere but the more common methods include, unit, integration, stress, performance and system testing.
Unlike development processes, however, rigorously defined test methodologies as a standalone practice is lacking. Instead, QA standards are set by a variety of bodies including ISO and CMMi.
Testing is a very general term covering a huge field, so there are a lot of methodologies involved, e.g. risk-based testing, model-based testing or random testing.
It actually makes sense to build a taxonomie, differentiating e.g. manual vs automated testing, white-box vs. black-box testing and the level in the V model (unit, component, system). Here is a mindmap that gives a rough taxonomie.
If you come across a technical term, you will probably find it in this glossary from ISTQB, which is by far the best I know of. ISTQB also offers several syllabus in which you can read up what the terms mean. This foundational syllabus is a good start.


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| Billy Thinnes, Hydrocarbon Processing,
[industrial services]
SULPHUR, Louisiana -- On a cool and
overcast evening in southeastern Louisiana, NAES opened a new
facility for its industrial services division. The
company, which is a broad-based provider of services to the
energy industry, saw an opportunity to establish a foothold in
the Gulf Coast refining and construction services market, and
they jumped on it.
The new office in Sulphur, Louisiana,
will afford NAES the ability to bring its brand of safe,
reliable and cost-effective construction, retrofit and maintenance services to the hydrocarbon processing industry.
The open house and ribbon cutting ceremony
at the facility on Carbide Drive was attended by the Sulphur
mayor and a smattering of city council members, as well as
executives from NAES and employees from local refining and processing
"NAES is excited to open this new facility
and a new chapter in our history," said Kevin Taylor, NAES
senior vice president of engineering and construction.
"This new facility will support our
efforts to provide the highest quality of services as this
centralized location enhances our capacity to respond to
customer needs, more effectively mobilize, and provide
employment opportunities to the local community," he added.
Headquartered in Issaquah, Washington,
NAES provides comprehensive services to the generation
industry, and is expanding its services to industrial
infrastructure markets. The company is a part of ITOCHU
Corp. ITOCHU operates in over 80 countries and
covers a broad range of industries.
All comments are subject to editorial review.
All fields are compulsory.
Roy M. Christoffel
Scott, they are a customer in the Houston area.
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A searchable database of project activity in the global hydrocarbon processing industry
Engineers and designers are highly skilled individuals. Forcing them to enter design changes using tables, forms and spreadsheets is unproductive and uneconomical, and it increases the likelihood of human error—this is the way that most instrumentation software systems currently work. For too long, software vendors have denied engineers and designers the simple practicality of a graphical visual engineering interface with "drag and drop" capability and inbuilt intelligence, ensuring changes are automatically replicated into all the associated data and databases.
Is 2016 the peak for US gasoline demand?
Too soon to tell
July 2016


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Is it possible to use the zoom in, zoom out, and previous extent functions as mouse gestures in ArcMap? For example, say a user held down LShift then left click and dragged diagonally to the lower right. I would like that to function the same as zooming in, using the zoom in tool. Dragging in a different direction would do one of the other functions. A final function would be escaping from the command after a drag has been started, this would be the same as hitting the Esc button.
I assume this would have to be done in ArcObjects. I've done some searching around for zooming functions in ArcObjects but most of the stuff I've found refers to older versions. I'm not at all familiar with ArcObjects, so some pointers would be very helpful. I have access to both Arc 9 and 10.


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Release date:
March 30, 2012
(3D/2D theaters and IMAX)
Studio: Warner Bros. Pictures
Director: Jonathan Liebesman
MPAA Rating: PG-13 (for intense sequences of fantasy violence and action)
Screenwriters: Dan Mazeau, David Leslie Johnson
Starring: Sam Worthington, Rosamund Pike, Bill Nighy, Edgar Ramirez, Toby Kebbell, Danny Huston, Ralph Fiennes, Liam Neeson
Official website: WrathoftheTitans.com
Plot Summary:
A decade after his heroic defeat of the monstrous Kraken, Perseus (Worthington) --the demigod son of Zeus (Neeson)--is attempting to live a quieter life as a village fisherman and the sole parent to his 10-year old son, Helius. Meanwhile, a struggle for supremacy rages between the gods and the Titans. Dangerously weakened by humanity's lack of devotion, the gods are losing control of the imprisoned Titans and their ferocious leader, Kronos, father of the long-ruling brothers Zeus, Hades (Fiennes) and Poseidon (Huston). The triumvirate had overthrown their powerful father long ago, leaving him to rot in the gloomy abyss of Tartarus, a dungeon that lies deep within the cavernous underworld. Perseus cannot ignore his true calling when Hades, along with Zeus' godly son, Ares (Ramirez), switch loyalties and make a deal with Kronos to capture Zeus. The Titans' strength grows stronger as Zeus' remaining godly powers are siphoned, and hell is unleashed on earth. Enlisting the help of the warrior Queen Andromeda (Pike), Poseidon's demigod son, Argenor (Kebbell), and fallen god Hephaestus (Nighy), Perseus bravely embarks on a treacherous quest into the underworld to rescue Zeus, overthrow the Titans and save mankind.