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2 reviews | 3.5 out of 5
The slippers looked like good quaity and thought they would be very comfortable. Unfortunatly we ordered a large (mens 11-12) rec'd a small (mens 7-8). Cant wear them have to return. Hope they are as comfortable as they seem.
These slippers run big in size. I purchased the mens small (7-8) for my son who wears a mens 8.5 sneaker and was concerned they may be small but it is just the opposite. They are too big for him. He is only 13 and wants to keep them anyways but just beware of the sizing. Other than the size, he loves them.

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Someone whs born on valentines day
Valda was born on febuary 14 thats where she got her name from!
by TapeJunkie. March 15, 2009
Trending Now
To completly and udderly disregard your freinds in need in a rude or diturbing behavior. To blatently disregard your freinds.
Man I needed a ride but they just drove past me. What a valda!
by jchap078 June 06, 2011


text:
The Clinton Tease
When Al Gore endorsed Howard Dean in December, he didn't just inject himself in a primary, he turned himself into a story line. According to various talking heads, Gore's endorsement was a continuation of both his war with Bill Clinton and a larger war for the Democratic Party. So when news leaked this week that Clinton might be quietly helping Wesley Clark in his campaign for president, all the pieces seemed in place to fulfill the narrativeold left versus new center, populist Al Gore versus pragmatic Bill Clinton.
Not so fast. Mark Benoit, New York State director of the Clark campaign, concedes that a Clinton endorsement would "blow the roof off." But according to Benoit, Clinton is still neutral. "I will say that there is an affinity and a warmth" between Clark and Clinton, says Benoit. "But I don't see [an endorsement] happening. I have seen no evidence of fundraising help. I don't even know where that talk comes from."
Clinton is reported to have once called Clark one of the Democratic Party's two starsthe other was his wife, Senator Hillary Clinton, who's widely thought to have an eye on a presidential bid of her own in 2008. (Neither Bill nor Hillary responded to a request for comment.)
The latest talk of machinations by Bill for Wesley were reported in the New York Post last week, then picked up by broadcast media. "Bill is said to be personally involved and it's believed he's begun making money calls on Clark's behalf," the paper quoted an anonymous, well-connected Democratic activist in New York as saying.
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But what has given the story legs is Gore's endorsement of Dean, and the potential juice and headlines that would come from the extension of a Gore-Clinton feud. But in presidential primaries, the party's big guns rarely inject themselves into the infighting that characterizes most races, preferring to hold their wordsand their cloutuntil a winner has been picked.
"Gore's decision to endorse Dean very early in the process was viewed as unusual," says Costas Panagopoulos, executive director of the political campaign management program at NYU. "But the fact is that there are no rules in politicswe break them as quickly as we make them up. I think it was a strategic decision because the leading contenders are within a few percentage points of each other. Anything can make a huge difference."
But despite reports of a feud between Clinton and Gore, a counterattack by Clinton is unlikely, says Panagopoulos. "My expectation is that the Clintons, both Bill and Hillary, will play sort of a behind-the-scene role in this presidential campaign," he says. "I think they will make the obligatory appearances and they will show support for the nominee, but my expectation is that they will be less visible than one may expect."
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Results 1 to 10 of 108
Thread: Severing ties with parents...
Jun 28, 2013, 03:55 PM
'; pd[174765] = '
Jun 28, 2013, 03:56 PM
\nA little less talk and a lot more action would do you more good than you know.
'; pd[174757] = '
Jun 28, 2013, 03:33 PM
\nThis is Murica, land of the free, home of the brave, remember? Tell some guy who just came over from another country with nothing but the clothes on his back and a dream of being FREE that there is no opportunity in this country. Immigrants, illegal and legal alike, all come here because it's the best country to live in the world, and offers the most opporunity, the American Dream still exists, but you won't find it thinking that way.
\nAs much as the economy has sucked lately, it's still better than the alternative. Plenty of jobs out there, just gotta open your mind some and see what's available. Trying to follow in your Father's footsteps is too cliche bro, don't fall into that trap and limit yourself. Some would turn their noses up at a McDougal's job, but I could walk down the street right now and find 10 people in an hour who probably would be happy to have that job (better than panhandling), so keep that in mind when you're out in the world and don't see anything opportunties.
'; pd[174789] = '
Jun 28, 2013, 04:30 PM
Agree and disagree... I'm around the same age as you. I think our parents had it easier as far as buying a home. I know my parents would have never been able to buy their home today the way they did in the 70's. The price of homes has gone up so much more than the average salary.
\nThat being said. You can still get a job and rent a place. I'm just saying buying a home is way more difficult for us than it was our parents.
\nAs for the illegals. A good portion are not living the "American Dream." They live in small apartments with a lot of people and send all their $ back home to their families. Once they have sent enough they go back and are living the dream back in their home country.... Not all of them, but a good amount.
'; pd[174798] = '
Jun 28, 2013, 05:19 PM
\nI agree with you on the illegals though, they sure do like to pack into a small apartment / house and save up all their money to send back home, but that's THEIR choice, they could just as easily decide to make a real life right here in the states if they were to become LEGAL. And honestly, If they aren't legal, then I could give a rats ass if they live the American Dream, because they are in fact, NOT AMERICAN HAHAHA
Last edited by DawnPatrolSUP; Jun 28, 2013 at 05:30 PM.
'; pd[174770] = '
Jun 28, 2013, 04:12 PM
\nYour "generation in general" sucks. Partly due to improper rearing by nuclear home and society (improper meaning suppression and inhibiting personal growth), and partly due to a rampant void or resilience, ambition, autonomy, and relentlessness pursuit of goal achievement in the face of adversity. Focus less on the consortium of peers that are crying victim like you and just go make it happen no matter what stands in your way.
\nOur parents "were set" not because of handouts. They were set because they were more likely to have core values that most lack today. Their moral code told them it was right to have loyalty, duty, commitment, and perseverance. Was it a perfect place? Far from it. But very accountable as a whole and one that proliferated itself successfully despite having major societal barriers (Civil Rights, counterculture, Vietnam, etc.) in the way. A nation still finding itself and most people got er done.
\nSpeaking of...go talk to an elderly African-American about what segregation was like. You might have a new definition of "lack of opportunity" after that.
\nBet you're pissed that NASA won't let you be an astronaut or that Major League Baseball won't let you forgo the minor leagues so you can go straight to big league ball player like many a kid grows up dreaming of.
\nGet your own pot to piss in, with your name on it. Piss in that pot for an extended time period. Learn something (anything) about life, then we can talk.
'; pd[174884] = '
Jun 29, 2013, 01:05 AM
F'in A Emass, what happened man? You came out cold, talking about bringing your beginner friend into some miracle 10'+, jetty-created surf on a day when nowhere else in New England was above 3', fought through the attacks and really (no sarcasm here) dropped some gem posts that were insightful and well-thought, and now you go off on this thread like this? I'm so disappointed, you were climbing the ranks of the SI posters for me.
\nI'm from the generation you seem to harbor so much dislike for. And man, Emass, as someone who works his a** off for everything I have, I think you're making some strong generalizations that maybe you, as someone who is neither part of the generation you are so readily trashing, nor has a child in that one to provide a solid look into (I assume you don't, unless you were getting after the d*** thang far younger than I), aren't in the best position to make, and I, respectfully of course, agree that you should get off your freaking high horse. You asked for your examples? Let's start here:
\nAnd for the record, I'm not in anyway positing that we have it harder than previous generations, as you seem to insinuate that I, as a member of my generation, must think I do. I'm grateful for what I had,and work my tail off to try to find more. But please, don't turn into the crotchety old man talking down at younger generations already - you're in your early 30s! How bad will it be when you're 70?
\nBack in Emass' day, they had to walk 15 miles, through the snow, both ways, to take their friends out for a nice 10' drop onto a jetty.
Last edited by newenglandflatness; Jun 29, 2013 at 01:08 AM.
Reason: I'm a lazy typist
'; pd[174893] = '
Jun 29, 2013, 02:31 AM
Another couple things about how hard it is to buy a house these days:
\n1) Predatory lending aside (never helped anything), people young or old now who are having a heck of a time getting mortgage financing can thank the legions of sub-prime loan customers that defaulted their way into our economy's default. Just a couple years ago, you could walk into a bank and walk out with a mortgage faster than your Dad walked in and out of the five-and-dime for PEZ decades ago. Wasn't set up for success, but it wasn't the lenders that missed the payments was it? Always seems to be someone else's fault. Let's have a spelling bee: A-C-C-O-U-N-T-A-B-I-L-I-T-Y. Sparky, could you now please use that word in a sentence? "Yes; there are many people in today's society that are not in any way accountable for their actions."
\n2) In November of 1978, the average interest rate on a 30-yr fixed mortgage broke double digits to 10.11, and rates stayed in double digits on average until 1991. In October of 1981, the average rate was 18.45%. January 2013 saw a rate of 3.41%. My parents paid, over the course of their loan term, 5.5x the value of the original purchase price. That's not including any insurance or repairs which adds up beyond belief. These days, you only pay for your house twice.
\nYou want to buy a house soon out of college in your mid-20s? First off, that's a ton of responsibility and renouncing of some of your freedom. Secondly, the way to do it is not to blow your a quarter mil on a private college and go to state school instead. Won't even be six figures in the end. In several states, high academic achievers in high school go to state schools nearly for free.
'; pd[174896] = '
Jun 29, 2013, 02:40 AM
and honestly man, we should go for a surf sometime. SI Massachusetts rock the world. We can banter in person and subsequently realize that neither of us are such bad guys. Just don't take me near any jetties (I kid, I kid).
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Jun 29, 2013, 03:12 AM
Last edited by EmassSpicoli; Jun 29, 2013 at 03:21 AM.
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Jun 29, 2013, 03:18 AM
Fingers crossed for Sunday though, could be a bit of fun.
'; pd[174825] = '
Jun 28, 2013, 06:57 PM
Senior Member
- Join Date
- Oct 2012
- Posts
- 1,117
Your parents are not pushing you out of the nest. You will have to throw yourself out there. Go rent an apartment and get on with life! It's anxiety arousing for sure,but also fun and confidence building. It's safer than riding a big wave.
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Jun 28, 2013, 07:07 PM
Senior Member
- Join Date
- Jun 2013
- Location
- Posts
- 285
'; pd[174832] = '
Jun 28, 2013, 07:09 PM
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Jun 28, 2013, 02:40 PM
Senior Member
- Join Date
- Jun 2013
- Location
- Posts
- 285
See the example I gave about my father and the Navy. That wasn't available to me
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Jun 28, 2013, 02:44 PM
'; pd[174760] = '
Jun 28, 2013, 03:51 PM
\nA military officer is managing the enlisted. This is our national defense system here. "Leading the troops", you know? So they're supposed to roll a red carpet out to a kid that may have never got up at 4am once ever when he's supposed to lead PT or formation 30-60 minutes from that time each day?
\nHave you looked into OCS and filed any initial paperwork with MEPS? Have you researched what boot camp entails, let alone the schools that follow it specific to OCS and A-school if you're an exceptional performer out of the exceptional population? Why do you consider a military officer career? Because its sounds valiant or your father did it? Or because declining all the pleasures and benefits of civilian life (that are protected by the military) are a small exchange to you for the desired life of duty towards man and country?
\nIf you do happen to have a core of integrity somewhere inside of you, look into the process. There are many, many DQ factors but saying it's not available to you because of GPA or anything on merit is a false statement. If that's your DQ, it WAS available to you before you decided not to earn elite marks. If it's truly for you, and I'm betting it's not (only you know that), go talk to the right recruiter (not just any when it comes to OCS), take your ASVAB, and see how it goes.
\nYes, much of the world was very different when your father went OCS. War was far differently executed, we had presidents that consistently supported military spending, we had a higher need of troops, and the pool of applicants was not the product of a soft society. You're also talking about USCG which has next to no spots for OCS as well as Navy OCS which has several entry routes but is very selective. Have you read up on Army National Guard? You can even enter on your state's level. Much simpler route of entry than the others and still plenty to be proud of and serve your fellow man. Who do you think was called in by the tens of thousands to assist with Sandy last October? ANG.
'; pd[174769] = '
Jun 28, 2013, 04:04 PM
Emass, is it true when they say that first hit of meth in the morning is the best?
'; pd[174773] = '
Jun 28, 2013, 04:16 PM
\nFor me though, the first sight of the Atlantic when I look out my window in the morning IS the best. Just like the first wave of the day.
'; pd[174772] = '
Jun 28, 2013, 04:14 PM
Will you PLEASE answer the man's question?
'; pd[174774] = '
Jun 28, 2013, 04:16 PM
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Jun 28, 2013, 04:18 PM
'; pd[174784] = '
Jun 28, 2013, 04:26 PM
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Jun 28, 2013, 04:29 PM
\nGotta get moving now and head to the break. Chest high with offshores at optimal tide. Thanks to this, I can now cancel my order for that Arizonan wave pool that was being loaded for freight shipment. Have fun in whatever cubicle cage or parents' basement yous guys are rocking out in today!
'; pd[174777] = '
Jun 28, 2013, 04:19 PM
'; pd[174781] = '
Jun 28, 2013, 04:22 PM
\nJust because I'm dropping knowledge on those needing it in no ways makes me lacking calmness. I'm not aggro at all today, but I'm definitely stoked to hit first waves of the week now that there's some swell at all. So if stoked, jubilant, and enthusiastic makes me not calm, I guess you're right on!
'; pd[174787] = '
Jun 28, 2013, 04:27 PM
'; pd[174786] = '
Jun 28, 2013, 04:27 PM
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Jun 28, 2013, 04:32 PM
- Join Date
- Aug 2010
- Location
- Posts
- 3,159
- Images
- 1
Without reading all the pages of jibberish... i will add my 2 cents that I learned from experiance... I would say stay with the parents for as long as possible- or at least until you can save up some money to put a good down payment on a house...
I moved out right after high school- from PA to NJ and lived with my uncle for a short time. Then got an appartment- i was probably around 20... it was really cool- granted... and i was living 'the life' - surfing all the time!! living a few blocks to the beach- working an easy job... but now looking back and with a little more wisdom at the same time looking forward at family and stability- its alot of hard work to try to dig out of the rent situation unless you got a sweet job. I rented for years and look back and feel like renting is basically throwing away money... now money is not everything, but you will need it to live and to provide for your family.
Maybe I sound like an old dude or something- but I would suggest staying- even if its one year and bank almost all your paycheck to buy a house instead of renting. If you can buy now- go for it. Also-family is pretty important, you find that out the older you get... so live it up while you can with the parents!
'; pd[174802] = '
Jun 28, 2013, 05:32 PM
Senior Member
- Join Date
- Apr 2013
- Location
- Oregon
- Posts
- 115
Haven't lived with my folks since I was 18. Was economically tough right out of college but I scraped by. 31 now and I've moved all around the northeast, moved for a girl I almost married. Some places were better than others, but as someone who's been locked into living somewhere because of a commitment to someone...get the hell out if you're not happy and you have no ties there. Unless it's some amazing career opportunity you can't pass up, leave. Use your freedom to your advantage and move somewhere you've always wanted to live. Be smart about it, save money, vacation days for quitting time, move somewhere you know someone who can help you out for a bit, etc.
Seriously, if I was in your shoes at your age, I'd be outta there if I didn't like it. It'll be soon enough before you meet another woman and tie yourself down again...take advantage of the freedom while you have it.
'; pd[174803] = '
Jun 28, 2013, 05:37 PM
Senior Member
- Join Date
- Jun 2013
- Location
- Posts
- 285
I'm not concerned about being tied down to a woman.. Not my style at all. I've always loved the Northeast. My grandparents live in Hingham MA and I lived in Middletown RI for a couple years. I think I might save up for the next year to buy a townhouse in RI. It would be tough but I know I'd be happy
'; pd[174805] = '
Jun 28, 2013, 05:46 PM
Even though I initially said eff it, go for it, if you did stack money for a year you'd be glad you did, even more so when you get that townhouse...in which case, are you hosting the first annual SI New England meet and greet?
'; pd[174807] = '
Jun 28, 2013, 05:57 PM
Senior Member
- Join Date
- Jun 2013
- Location
- Posts
- 285
Absolutely! I'm looking forward to the Newport Creamery and some Dell's lemonade. Also Papa Gino's pizza
Last edited by Bill Cosby's nephew; Jun 28, 2013 at 05:58 PM.
Reason: spelling
'; pd[174809] = '
Jun 28, 2013, 06:02 PM
Dude Dell's is the $hit! I personally love the watermelon flavor
'; pd[174824] = '
Jun 28, 2013, 06:54 PM
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Jun 28, 2013, 07:02 PM
'; pd[174823] = '
Jun 28, 2013, 06:53 PM
Emass: Get off your high-horse man, it would be much easier to digest the few gems of insight you have randomly placed in your litany of posts on this subject. Your self-felation amazes me, I bet the area around you looks like someone blew up a barrel of yogurt after you post some of that crap.
\nBCN: I want to reiterate what some others have said here-' + '-save up money for at least 9 months before you make a move. Save hard, live like a monk.... a surfing monk. Also, don't go buy a turn-key house if you are planning to go that route. If you have moderate construction skills go buy a complete dog of a house and fix it up as you live in it. I'm talking something under $30,000.
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Threaded View
Jun 29, 2013, 02:31 AM #11
Another couple things about how hard it is to buy a house these days:
1) Predatory lending aside (never helped anything), people young or old now who are having a heck of a time getting mortgage financing can thank the legions of sub-prime loan customers that defaulted their way into our economy's default. Just a couple years ago, you could walk into a bank and walk out with a mortgage faster than your Dad walked in and out of the five-and-dime for PEZ decades ago. Wasn't set up for success, but it wasn't the lenders that missed the payments was it? Always seems to be someone else's fault. Let's have a spelling bee: A-C-C-O-U-N-T-A-B-I-L-I-T-Y. Sparky, could you now please use that word in a sentence? "Yes; there are many people in today's society that are not in any way accountable for their actions."
2) In November of 1978, the average interest rate on a 30-yr fixed mortgage broke double digits to 10.11, and rates stayed in double digits on average until 1991. In October of 1981, the average rate was 18.45%. January 2013 saw a rate of 3.41%. My parents paid, over the course of their loan term, 5.5x the value of the original purchase price. That's not including any insurance or repairs which adds up beyond belief. These days, you only pay for your house twice.
You want to buy a house soon out of college in your mid-20s? First off, that's a ton of responsibility and renouncing of some of your freedom. Secondly, the way to do it is not to blow your a quarter mil on a private college and go to state school instead. Won't even be six figures in the end. In several states, high academic achievers in high school go to state schools nearly for free.


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In semiconductor lasers, the unpumped cladding region outside the optical waveguide is nominally lossy. Since the evanescent tail of higher-order waveguide modes extends further into the waveguide cladding, the modal loss increases for high spatial frequency perturbations, creating a weak spatial filter. Increasing the effective laser cavity length in a broad-area laser enhances the effect of this spatial filter, resulting in improved beam quality. Simulations predict that by optimizing the lateral index step and output coupler reflectivity, a factor of two increases the beam brightness with only a 10% penalty in electrical-to-optical efficiency.
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Three-Dimensional (3-D) Synthetic Aperture Radar (SAR) Image Formation and Exploitation
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AbstractOur main objective is to develop, implement and test novel level-set surface reconstruction methodologies as applied to SAR data that has been collected over a sparse 3D aperture. We believe a tomographic surface reconstruction can best exploit nonlinear models and sparse data collection geometries: These configurations are not readily amenable to more traditional Fourier-based or filtered back-projection (FBP) reconstruction methods. Phase I of this effort will comprise a proof-of-concept stage during which both the radar signal processing, imaging algorithms and hardware implementation concerns will be addressed directly. We will demonstrate a functionality that will effect 3D imaging using existing, albeit augmented, techniques, as well as new capabilities that will effect 3D surface reconstruction via novel level-set techniques. Throughout we will emphasize the development of a solution methodology that is aligned with the end-to-end goal of obtaining a fieldable and modular set of integrable components. Phase II will concentrate on the further development, larger-scale implementation, testing and performance analysis of the techniques developed under Phase I. This includes integration and testing in a lab setting of a modular prototype system using the components developed in Phase I.
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"It's hard to imagine a book that makes a broader and deeper examination of social media than Content Nation—or that gives more useful advice." —David "Doc" Searles, coauthor of The Cluetrain Manifesto
"The enthusiastic message John Blossom spreads in Content Nation is: Become your own media, engage, share, participate, make your voice heard!" —Robin Good, social media pioneer and editor of Robin Good's MasterNewMedia
From cave paintings to Craigslist—the content evolution
This book is revolutionary not only in its scope, but in the way it came to be. Through the wiki collaboration process, it evolved and developed online at ContentNation.com—literally created by the social media it examines. Hundreds of individual publishers contributed to its content. If you have sent an e-mail, voted in a Web poll, posted a video on YouTube, or sent a text message, you are part of Content Nation. Welcome to the evolution.
Examine what it means to be a provider of content in a global environment
Explore the challenges to marketing, enterprise, and government
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In an attempt to provide advertisers with a new way to measure site traffic, comScore has added a new metric to its Media Metrix subscription reports: the visit. A visit measures the number of distinct times people visit a site per day, with at least 30 minutes between each visit.
"We wanted to get more into engagement and intensity of usage, and help better understand who the audience is," Jack Flanagan, EVP at comScore Media Metrix, told SEW.
Visits will augment the "frequency" metric, which counts the average number of days per month a user visits, and "unique visitors," which counts the total number of people who visit in a month. Its advantage over "unique visitors" is that it can show more details on user engagement, Flanagan said. For instance, a visitor that comes to a site once in a month will be counted as one unique visitor, as will a visitor that comes to the site every day that month. With visits, that user can be shown to be a loyal visitor, who visits the site multiple times a day.
This is the first new metric comScore has added in a while, and it was mostly driven by the growing dissatisfaction with the pageview as more sites begin implementing technologies like Ajax or Flash that limit the usefulness of measuring an html-based action like a pageview.
In a post on Yahoo's Yodel Anecdotal blog last week, Chief of Insights Peter Daboll said he found that visits could be a useful addition to his analytics reports.
"With 'visits,' we get an added layer of data that, combined with reach (the number of users) and engagement (how long they stay), yields a much more comprehensive and meaningful portrait of people's interactions and activities online," he said.
Daboll was quick to point out that the visit is not a "silver bullet," given its limitation on measuring ad consumption and impressions. But it does provide more information for publishers to show how the value of its users.
"What it does provide is a valuable reference for advertisers to determine where to increase their ad exposure and budgets. The more loyal users and 'visits' a site has, the more opportunities a particular ad has to be seen. It's also a key measure of a site's value and impact to a consumer's life," Daboll said.
Flanagan said that the issue of ad impressions is being addressed with another product, Ad Metrix, which comScore is currently working on. That product, currently in beta, will report ad impressions and ad-exposed unique visitors, and will be available some time this summer, he said.
UPDATE: ComScore issued a press release this afternoon that provides more details, and shows the visits metric in action.
Related reading
15 data visualisation tools to help you present ideas effectively
The number of digital skills you need in order to be a functional and useful member of your organisation are increasing at a rate you might be struggling to keep up with.
Tie your web, and mobile properties together in Search Console, plus three more recent changes
Since writing our comprehensive and barn-stormingly popular complete guide to Search Console a couple of weeks ago, Google has since released a few updates to make webmasters lives a darn sight easier.
Google launches Firebase Analytics for mobile apps
Google has launched Firebase Analytics, a new analytics solution for mobile apps, at this year's I/O 2016 developer conference.
Google Search Console: a complete overview
The Search Console (or Google Webmaster Tools as it used to be known) is a completely free and indispensably useful service offered by Google to all webmasters to help optimise their sites for search.


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Tearful memorial service as family, friends and colleagues filled an auditorium at the Kyalami race track.
The unstable relationship between Lewis Hamilton and Nico Rosberg threatened to boil over after Sunday's race.
Historic moment as Solar Impulse becomes the first plane to circle the globe powered only by the sun.
Toyota has increased the local content of its latest Hilux bakkie, while demand still outstrips supply.
It wasn't long ago that BMW denied that it would ever build a bakkie, but that might be about to change.
Motorists could enjoy an even bigger fuel price reduction than originally anticipated if current trends persist.
More snow forecast in some areas as many high-lying regions are transformed into a winter wonderland.
Three sessions of negotiations have failed to achieve agreement on any of the union's demands.
As SA remembers Zulu at a memorial service, Jovial Rantao ponders the disgrace of his death on Kilimanjaro.
Several high-profile incidents over the Hungarian Grand Prix weekend triggered debate on how they should be applied.
Mercedes-Benz SA stages an automotive Moulin Rouge, as the new SLC and the revised SL go topless in one roadster rush.
Car companies are under increasing pressure to find ways to guard against cyber-attacks.
Road test: M2's been touted as an M-car to rival all before it. We find out if it really lives up to the hype.
Dutch teenager defends his tactics to hold off attacks from Kimi Raikkonen after their battle in Sunday's Hungarian Grand Prix.
South Africa's international contingent of racing drivers battled through an extraordinarily difficult weekend all around the world.


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Get a free shipping quote.
Very sweet and loving purebred registered filly. Lots of potential for Hunter, Sporthorse, Dressage, Endurance, Etc. She is good to load, clip, lounge, catch, trim. All around great mare. Great pedigree can be seen at the following link
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Watch Stonehurst Media - HS Paradise
More Pics and info available.
We train and work with a variety of horses rescued from auctions and owner surrenders. We also work with Arabians and Half Arabs.
Avoid Scams and Fraud - Potential areas of fraud: wire transfer, moneygrams, money orders, cashier checks, shipping, escrow, "transaction protection", "guarantee". Check out the Buyer Safety section for more info.


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The Homer: I See You in There
Fans of The Simpsons will know The Homer, the car that Homer Simpson designed along with his brother, who happened to be the owner of Powell Motors. This episode (from Season 2) was written as a spoof on the Edsel, which we all know ended sadly. In this episode, Homer designs "The Homer" which brings his brother's car company to ruin.


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July 2016
Latest wallpaper collections
Be inspired by our latest new collections…
Flora Wallpaper Collection
by Sandberg
• Monday 25th July 2016
A selection of these beautiful Swedish designs, with the theme of 'flowers'. Designs cover a variety of styles and moods, from bright and cheerful, to atmospheric and subtle.
Browse the Sandberg Flora Wallpaper Collection
Sandberg Wallpapers
£68.00 per roll
Sandberg Wallpapers
£89.00 per roll
Sandberg Wallpapers
£89.00 per roll
Sandberg Wallpapers
£68.00 per roll
Signature Florals Wallpaper Collection
by Ralph Lauren
• Monday 25th July 2016
A beautiful selection of these classic designs: shirting stripes and old fashioned florals, perfect for that traditional English country garden look.
Browse the Ralph Lauren Signature Florals Wallpaper Collection
Basil Stripe
Ralph Lauren Wallpapers
£55.00 per roll
Francoise Bouquet
Ralph Lauren Wallpapers
£71.00 per roll
Marston Gate Floral
Ralph Lauren Wallpapers
£83.00 per roll
Mapleton Stripe
Ralph Lauren Wallpapers
£55.00 per roll
Regency Wallpaper Collection
• Monday 18th July 2016
A traditional and classic collection of wallcoverings, designs include toiles, damasks, and co-ordinating stripes, scrolls and tile and fabric effects in a small palette of colours, making them perfect to use together to create a unified look. Metallics inks and flock patterns are also included in this classic but modern collection.
Browse the SketchTwenty 3 Regency Wallpaper Collection
SketchTwenty 3 Wallpapers
£103.00 per roll
Royal Stripe
SketchTwenty 3 Wallpapers
£52.00 per roll
Royal Stripe
SketchTwenty 3 Wallpapers
£52.00 per roll
SketchTwenty 3 Wallpapers
£52.00 per roll
Ambleside Fabric Collection
by Prestigious
• Monday 18th July 2016
This elegant fabric collections conjures memories of long country walks on Autumnal afternoons. Featured designs include wild flowers, roses, leafy springs and hedgerow fruits. Available in a range of colours including berry, foxglove and burnt oranges. Please request a sample for a true colour and texture match.
Browse the Prestigious Ambleside Fabric Collection
Prestigious Fabrics
£14.00 per metre
Prestigious Fabrics
£14.00 per metre
Prestigious Fabrics
£14.00 per metre
Prestigious Fabrics
£14.00 per metre
Samba Fabric Collection
by Prestigious
• Friday 15th July 2016
A beautiful selection of colourful weaves and velvet fabrics. From the richly embroidered detailing of Flamenco to the cut away, textural velvet like Cha Cha design, these are fabrics for every room. In three seperate colour blocks: Topaz with its blue, lime and amethyst, Spice with bold oranges and reds and the cool Colonial with its blues, taupe and ivory
Browse the Prestigious Samba Fabric Collection
Lakeside Fabric Collection
by Prestigious
• Thursday 14th July 2016
Perfect for laid-back interiors, this collection features a variety of designs perfect for any home. Designs include a crewel work trail and coordinating trellis, classic stripes and checks in colours such as aqua, willow and natural. A mixture of polyester and cotton weaves and embroidered designs in faded muted colours.
Browse the Prestigious Lakeside Fabric Collection
Bridgehampton Fabric Collection
by Thibaut
• Wednesday 6th July 2016
A beautiful fabric collection, perfect for adding a touch of Summer style to your home, whatever the weather! Designs include painterly florals, small scale geometrics, and trailing patterns. Reflecting the beautiful open air, classy Hampton community its named after, this sophisticated collection has designs for every room.
Browse the Thibaut Bridgehampton Fabric Collection
New England Plaid
Thibaut Fabrics
£66.00 per metre
Peacock Garden
Thibaut Fabrics
£84.00 per metre
Thibaut Fabrics
£69.00 per metre
Thibaut Fabrics
£75.00 per metre
Damask Resource Volume 4 Wallpaper Collection
by Thibaut
• Tuesday 5th July 2016
A stunning collection of classic and contempoary damask designs, in a wealth of colours and textures, including foil, flock, vinyls and woven textiles. Beautiful, and easy to live with, these wide width wallcoverings are a joy. Looking for some grown up stylish living then take a look at these designs.
Browse the Thibaut Damask Resource Volume 4 Wallpaper Collection
Pravata Damask
Thibaut Wallpapers
Private Damask
Thibaut Wallpapers
£180.00 per roll
Dorian Damask
Thibaut Wallpapers
£54.00 per roll
French Quarter Damask
Thibaut Wallpapers
£156.00 per roll
July 2016
The widest choice of wallpapers…
- Abigail Ryan
- Albany
- Alhambra
- Anaglypta
- Andrew Martin
- Anna French
- Anthology
- Architects Paper
- Art Decor Designs
- Arte
- Arthouse
- Baker Lifestyle
- Barbara Hulanicki
- Barneby Gates
- Beano
- Belynda Sharples
- Blendworth
- Boråstapeter
- Brewers
- Brewers Home
- Brian Yates
- By Lindholm
- C Brewer & Sons Ltd
- Camengo
- Carlucci di Chivasso
- Casadeco
- Casamance
- Caselio
- Christian Lacroix
- Clarissa Hulse
- Clarke & Clarke
- Cole & Son
- Colefax and Fowler
- Coloroll
- Creative Wall Art
- Crown
- Designers Guild
- Digetex
- Dupenny
- Duro
- Earth Inke
- Eco Wallpaper
- Eijffinger
- Ella Doran
- Emma Bridgewater
- Erica Wakerly
- Farrow & Ball
- Ferm Living
- FunToSee
- G P & J Baker
- Galerie
- Georgia Horton
- Ginger & French
- Graduate Collection
- Graham & Brown
- Harald Gloockler
- Harlequin
- Hattie Lloyd
- Hibou Home
- Holden Decor
- House Of Hackney
- Ian Mankin
- iliv
- JAB Anstoetz
- Jane Churchill
- Jocelyn Warner
- John Morris
- Julien Macdonald
- Kandola
- Katie Bourne Interiors
- Kelly Hoppen
- Kerry Caffyn
- Kids @ Home
- Larsen
- Laura Ashley
- Laurence Llewelyn-Bowen
- Layla Faye
- Lewis & Wood
- Liberty Fabrics
- Lincrusta
- Linwood
- Little Greene
- Lorca
- Louise Body
- Majvillan
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- Marcel Wanders
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- Matthew Williamson
- Mini Moderns
- Morris
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- Mulberry Home
- Murals
- Natasha Marshall
- Natureplus
- Neisha Crosland
- Nina Campbell
- One Direction
- Opus Muras
- Orla Kiely
- Osborne & Little
- Paper Moon
- PaperBoy
- Pip Wallpaper
- Prestigious
- Ralph Lauren
- Roald Dahl
- Roberto Cavalli
- Romo
- Sandberg
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- Screen Icons
- Sheila Coombes
- Sidney Paul & Co
- SketchTwenty 3
- Soleil Bleu
- Sophie Conran
- St Vitus
- Studio G
- Tapet-Cafe
- The Royal Collection
- Thibaut
- Threads
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- Vallila
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- Wall Word Designs
- Wallrock
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- Wedgwood Home
- William Yeoward
- Zoffany


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Hello to you here on Audiko.net! The best opportunity to download a free The Killers ringtones for your iPhone or mobile. Select your favorite line from your favorite track - Jeff The Killer - Sweet Dreams (Marilyn Manson & Creepypasta, Jeff The Killer - Sweet Dreams (Vocal Piano Ver.) feat. Lady, The Killers - Human, or any other track. Then download the prepared The Killers ringtones to your mobile device, and enjoy Indie music by The Killers every time your phone rings. You may get your ringtone both in the MP3 and m4a formats, compatible with both mobile phones and iPhones. Just select a track, and choose free The Killers ringtones download option.
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- deep - Beyoncé - End of Time


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2015 Teddy Bear Toss is a sight for more than just hockey fans
Dennis is a huge hockey fan and wanted to share this video as this may be one of the coolest sights during a game.
Dennis is a huge hockey fan and wanted to share this video as this may be one of the coolest sights during a game.
In case you missed it. Monroe hockey player Mikey Nichols joined me in studio to talk about the injury he suffered while playing in a high school ice hockey game.
There has been some great hockey already this season and the season is barely near the halfway mark of the year. That being said, we may have already witnessed the play of the year and it happened right here in NJ!
Normally, when a singer messes up the National Anthem, they are cascaded with a round of boos. Here's one time when the singer should actually be applauded.
What do you do when you play a pick up hockey game with one of the most feared leaders in the world? Let him win, of course!
Dennis is taking a break from showing you a good old fashioned hockey fight or a great hockey play to see if you can make sense of this video.
If you go to sporting events, you know all about the "Kiss Cam." They put the camera on a couple and try to get them to kiss. Some couple appease the crowd and kiss, others go over the top and make out and others, well just try and ignore it. One man at a Minnesota Gophers hockey game had the greatest response ready for the "Kiss Cam."
As we are in the middle of the Winter Olympics at Sochi, this marks the 34th anniversary of one of the greatest moments in U.S. Olympic history.
Sometimes karma takes months or years to appear but every so often, it pops up instantly and when it does, it can be glorious. This viral video is proof of just how amazing it can be.
Dennis is a die hard hockey fan as he talks about how much he loves the sport and how even though he is a Flyers fan, has an appreciation for some of the great players in the game, regardless of who they play for. One of those iconic players, is playing for the New Jersey Devils right now.


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volunteer jobs near Downers Grove, IL
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SAGA Fellow, Mentor & Tutor
SAGA Innovations - Chicago, IL
Prior paid or volunteer experience with students is helpful. ABOUT SAGA INNOVATIONS | Chicago*....
Workforce Connection Specialist
Goodwill Industries of Southeastern Wisconsin & Metropolitan Chicago - Chicago, IL
Communicate to customers, volunteers, co-workers, and supervisors in a professional manner. The Specialist must be able to effectively communicate with...
Vision Therapist
Clarendon Vision Development Center - Clarendon Hills, IL
Professional or volunteer experience in child development, education or rehabilitation is helpful, but not necessary....
Inside Sales
TransNational - Rosemont, IL
TransNational has deep charitable commitments including benefit concert, company sponsored volunteer day and company-matched charitable giving....
Logistics Broker
Echo Global Logistics - Skokie, IL
Endoscopy Tech I
Northwest Community Healthcare - Arlington Heights, IL
Approximately 800 volunteers providing more than 100,000 hours of service annually. Reporting to the Clinical Nurse Manager, provides equipment, specimen...
Lutheran Social Services of Illinois - Chicago, IL
Social Services, Human Services, Child and Family Services, Personal Care, Medical Health Services, Nursing, Family Therapists, Mental Health, Rehabilitation...
Certified Nursing Assistant - Full Time- Nights - 7:00 PM - 7:30 AM At Rush in Chicago
JourneyCare - Chicago, IL
Our team of Physicians, Advanced Nurse Practitioners, Registered Nurses, Social Workers, Chaplains, and Certified Nursing Assistants along with more than 1,500...
Scheduling Coordinator, Staffing Coordinator
The Villa at Evergreen Park - Evergreen Park, IL
Strong oral and written communication and teaching skills.Strong organizational and time management skills.Must be able to read, write, speak and understand...
Critical Care Staff Nurse - NICU
Northwest Community Healthcare - Arlington Heights, IL
Approximately 800 volunteers providing more than 100,000 hours of service annually. NICU - RN Part-time;...


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Unnecessary Surgery Part 2: Avoiding Hysterectomy and Prostate Surgery
…chance of developing heart disease and osteoporosis, and is often accompanied by weight gain, depression, and reduced sexual response. When Is Hysterectomy Necessary? For women with uterine cancer, severe pelvic infection, or uncontrollable bleeding, hysterectomy can be a lifesaver. But the vast…Read More


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Thu, Jun. 9, 1:04 PM
- Thinly traded nano cap SCYNEXIS (SCYX -23.8%) slumps on a 17x surge in volume, albeit on turnover of only 674K shares, in response to its announcement of results from a Phase 2 clinical trial assessing lead product candidate, Fast Track- and QIDP-tagged SCY-078, for the treatment of patients with acute vulvovaginal candidiasis (VVC), commonly known as vaginal yeast infection.
- The study randomized 96 women with moderate-to-severe VVC 1:1:1 to receive either of two dose regimens of SCY-078 or fluconazole, the standard-of-care prescription oral medication.
- Data from the Intent-to-Treat population all favored SCY-078, but the cure rate, defined by a negative culture, was only slightly better than fluconazole (70.3% versus 68.8%). The therapeutic cure rate, defined as a negative culture and the resolution of symptoms without further antifungal treatment (clinical cure), was identical (56.3%) for both.
- One significant negative was the "considerably higher rate of GI-related adverse events (diarrhea, nausea, vomiting, abdominal pain) in the SCY-078 arms compared to fluconazole. According to the company, they were "mild to moderate and transient in nature" with the majority lasting no more than one day after initiating SCY-078.
- SCY-078 inhibits an enzyme called glucan synthase. Its value proposition is comparable activity to echinocandins [e.g., Astellas' (OTCPK:ALPMF)(OTCPK:ALPMY) Mycamine (micafungin sodium) for injection] but available in an oral formulation and active against multi-drug-resistant pathogens, including those resistant to echinocandins.
Thu, Jun. 9, 8:31 AMAstellas initiates late-stage study assessing roxadustat in CKD-associated anemia triggering $10M milestone to FibroGen
- FibroGen (NASDAQ:FGEN) announces that collaboration partner Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY) has initiated a Phase 3 clinical trial in Japan evaluating roxadustat for the treatment of anemia in patients with chronic kidney disease (CKD) on hemodialysis. The action triggers a $10M milestone payment to FibroGen.
- Under FibroGen's 2004 license agreement with Yamanouchi (predecessor to Astellas), Astellas is responsible for the development costs of roxadustat in Japan and makes payments to FibroGen based on the achievement of certain milestones.
- Roxadustat is an orally administered small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase. HIF is a protein transcription factor that "turns on" the production of red blood cells (erythropoiesis). Its value proposition is the ability to maintain hemoglobin levels in CKD patients without affecting inflammation and potentially avoiding the need for ongoing intravenous iron repletion therapy as needed with epoetin alfa [Janssen's (NYSE:JNJ) Procrit]
Thu, Apr. 28, 11:37 AM
- Credit Suisse claims Medivation (MDVN +8%) is worth $55 a share, ~5% above Sanofi's (SNY -1.1%) unsolicited bid of $52.50. It says much of the attention has focused on the prospects of prostate cancer drug XTANDI (enzalutamide), approved by the FDA in August 2012, which generated $1.15B in the U.S. last year as reported by development and commercialization partner Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY). What appears to be underrepresented is the value of the company's pipeline, led by late-stage PARP inhibitor talazoparib.
- According to the analyst, other potential bidders include AstraZeneca (AZN -0.5%), Roche (OTCQX:RHHBY -0.5%) and Celgene (CELG +0.9%).
- AstraZeneca reportedly has held internal talks about an offer. Medivation rejected Sanofi's first approach several weeks ago, so the bidding could turn hostile if the board rejects $52.50, a likely scenario.
- Citi says Sanofi's offer is a bit light considering MDVN's 52-week high of $66.39, hit in June of last year. The board might reject the offer based purely on technical grounds.
- Previously: Medivation +9% AH on reported Sanofi takeover effort (April 12)
- Previously: Report: AstraZeneca held talks for Medivation bid (April 18)
Wed, Mar. 30, 8:22 AMVical's antifungal candidate VL-2397 Fast Track'd for invasive aspergillosis; shares up 16% premarket
- The FDA designates Vical's (NASDAQ:VICL) VL-2397 for Fast Track review for the treatment of invasive aspergillosis, an infection caused by inhaling the ubiquitous Aspergillus fungus. It is inconsequential in people with a normally functioning immune system, but can be dangerous in those with weakened immunity such as those undergoing hematopoietic stem cell transplantation, chemotherapy for leukemia or with AIDS.
- VL-2397, based on an isolate from a leaf litter fungus Acremonium species collected in Malaysia, was initially developed by strategic partner Astellas Pharma (OTCPK:ALPMF) (OTCPK:ALPMY). A Phase 1 study was recently initiated.
- The FDA designated it a Qualified Infectious Disease Product in August 2015 and an Orphan Drug in January of this year.
- Shares are up 16% premarket on increased volume.
Thu, Mar. 24, 8:31 AM
- The first patient has been dosed in a Phase 3 clinical trial, ARCHES, evaluating the safety and efficacy of enzalutamide with androgen deprivation therapy (ADT) compared to placebo with ADT in metastatic hormone-sensitive prostate cancer (mHSPC) patients. The global, double-blind, placebo-controlled study will randomize ~1,100 mHSPC patients to receive a once-daily 160 mg oral dose of enzalutamide or placebo, administered with ADT. The primary efficacy endpoint is radiographic progression-free survival up to four years.
- According to clinicaltrials.gov, the estimated final data collection date for the primary endpoint is April 2020. The estimated study completion date is December 2023.
- Enzalutamide, branded as Xtandi, is an androgen receptor inhibitor developed at UCLA by a team led by Distinguished Professor of Chemistry and Biochemistry Michael Jung. It was licensed to Medivation (NASDAQ:MDVN) in 2005 who sublicensed it to Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY) in 2009. The FDA approved it in 2012. Xtandi generated $1.15B in sales last year for Astellas.
- Previously: UCLA sells Xtandi royalty rights to Royalty Pharma for $1.14B (March 4)
Fri, Mar. 4, 11:18 AM
- Privately held Royalty Pharma acquires UCLA's royalty interest in the prostate cancer drug Xtandi (enzalutamide) for $1.14B in cash. The rights were jointly owned by the university, researchers working at UCLA at the time of the discoveries and a research organization. UCLA will use its share, ~$520M, to support research programs, undergraduate scholarships and graduate student fellowships.
- Enzalutamide, an androgen receptor inhibitor, was developed at UCLA by a team led by Distinguished Professor of Chemistry and Biochemistry Michael Jung. It was licensed to Medivation (MDVN +7.1%) in 2005 who sublicensed it to Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY) in 2009. The FDA approved it in 2012.
- Xtandi generated $1.15B in sales last year as reported by Astellas.
Mon, Feb. 29, 8:25 AM
- The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) adopts a positive opinion recommending approval of Boehringer Ingelheim's Giotrif (afatinib) for the treatment of patients with advanced squamous cell carcinoma of the lung whose disease has progressed on or after treatment with platinum-based chemo.
- The data supporting the application was generated in the LUX-Lung 8 study that showed a 19% improvement in progression-free survival in patients treated with afatinib compared to Genentech (OTCQX:RHHBY) and Astellas' (OTCPK:ALPMF)(OTCPK:ALPMY) Tarceva (erlotinib).
- Giotrif is currently approved for the treatment of EGFR mutation-positive non-small cell lung cancer.
- A final decision from the European Commission usually takes ~60 days.
Wed, Feb. 24, 8:39 AM
- Ironwood Pharmaceuticals (NASDAQ:IRWD) earns a $15M milestone payment from development and commercialization partner Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY) triggered by the latter's filing of a new drug application in Japan seeking clearance of linaclotide for the treatment of adults with irritable bowel syndrome with constipation (IBS-C). The milestone was stipulated in the companies' 2009 licensing agreement for the development of the product in Japan.
- Linaclotide, marketed in the U.S. under the band name Linzess, is a guanylate cyclase-C (GCC) receptor agonist. GCC is a key receptor for enterotoxins that cause diarrhea.
Tue, Feb. 16, 11:53 AMFibroGen's lead product candidate beats epoetin alfa in mid-stage study in CKD-related anemia; shares up 5%
- Data from a Phase 2 clinical trial assessing FibroGen's (FGEN +4.9%) oral agent roxadustat for the treatment of anemia in patients with chronic kidney disease (CKD) showed that patients on hemodialysis who were previously receiving epoetin alfa [Amgen's (AMGN +1.1%) EPOGEN or J&J's (JNJ +0.3%) PROCRIT] but switched to roxadustat maintained hemoglobin (Hb) levels regardless of iron deletion status, degree of inflammation or prior iron regimen over six or 19 weeks. The results were published in the American Journal of Kidney Disease.
- In the first part of the study, lasting six weeks, lowest dose roxadustat (1.0 mg/kg 3x/week) maintained hemoglobin levels on par with epoetin alfa. Some separation was seen at higher doses of at least 1.5 mg/kg with 79% of patients showing a hemoglobin response compared to 33% for epoetin alfa.
- In the second part of the study, 51% of the roxadustat cohort achieved a Hb level of at least 11.0 g/dL compared to 36% for epoetin alfa (normal range is 13.5 - 17.5 for men and 12.0 - 15.5 for women). In addition, maintenance dosing of roxadustat was not correlated with levels of the inflammatory biomarker C-reactive protein (CRP). Decreases in cholesterol and hepcidin (key regulator of iron) were also observed in the roxadustat group.
- Roxadustat is an orally administered small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase. HIF is a protein transcription factor that "turns on" the production of red blood cells (erythropoiesis). Its value proposition is the ability to maintain hemoglobin levels in CKD patients without affecting inflammation and potentially avoiding the need for ongoing intravenous iron repletion therapy as needed with epoetin alfa.
- It is currently in Phase 3 development through collaborations with AstraZeneca (NYSE:AZN) and Astellas Pharma (OTCPK:ALPMF) (OTCPK:ALPMY).
- Previously: Data from mid-stage study show CKD patients with anemia respond to FibroGen's roxadustat in dose-related manner (Aug. 13, 2015)
Wed, Feb. 10, 9:29 AM
- Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY) completes its tender offer for all issued and outstanding common shares of Ocata Therapeutics (NASDAQ:OCAT) at $8.50 per share.
- Previously: Astellas extends Ocata Therapeutics tender offer until February 9 (Jan. 22)
- Previously: Astellas Pharma buys Ocata Therapeutics for $8.50 per share in cash (Nov. 10, 2015)
Fri, Jan. 22, 9:37 AM
- In order to give Ocata Therapeutics (OCAT +1.6%) shareholders more time to tender their shares, Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY) extends its offering period to 5:00 pm ET February 9. The most recent period expired yesterday at 5:00 pm ET. All terms and conditions remain as is.
- Previously: Astellas Pharma buys Ocata Therapeutics for $8.50 per share in cash (Nov. 10, 2015)
Fri, Jan. 22, 7:22 AM
- The Japanese Ministry of Health, Labour and Welfare approves Amgen's (NASDAQ:AMGN) Repatha (evolocumab) for the treatment of patients with familial hypercholesterolemia or hypercholesterolemia who have a high risk of cardiovascular events and do not adequately respond to statins.
- Repatha was developed in Japan by Amgen Astellas BioPharma K.K., a joint venture between Amgen and Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY). The marketing application was filed in March 2015. It is the first PCSK9 inhibitor approved there.
- Regeneron (NASDAQ:REGN) and Sanofi (NYSE:SNY) are playing catch up with Praluent (alirocumab). They reported successful Phase 3 data in July.
Thu, Jan. 21, 4:03 PM
- Micro cap XenoPort (NASDAQ:XNPT) spiked at the close to finish up 9% for the day, albeit on below average volume, on a rumor that it is exploring a sale.
- Its markets one commercial product: HORIZANT (gabapentin enacarbil), for restless legs syndrome (RLS) and postherpetic neuralgia. It is branded as REGNITE in Japan, where Astellas Pharma (OTCPK:ALPMY)(OTCPK:ALPMF) exclusively markets it. It was cleared for the treatment of RLS there in January 2012.
- Its two main pipeline candidates are XP23829 for psoriasis and multiple sclerosis and XP21279 for Parkinson's disease.
Wed, Jan. 6, 7:22 AM
- The FDA designates Vical's (NASDAQ:VICL) investigational antifungal candidate, VL-2397, an Orphan Drug for the treatment of invasive aspergillosis, an infection caused by inhaling the ubiquitous Aspergillus fungus. It is inconsequential in people with a normally functioning immune system, but can be dangerous in those with weakened immunity such as those undergoing hematopoietic stem cell transplantation, chemotherapy for leukemia or with AIDS.
- In preclinical studies, VL-2397 has shown faster fungicidal activity compared to currently marketed drugs and activity against azole-resistant fungal pathogens. It was initially developed by Astellas (OTCPK:ALPMF)(OTCPK:ALPMY), which granted Vical an exclusive global license to develop and commercialize it in March 2015. A Phase 1 clinical trial should commence in H1.
- Among the benefits of Orphan Drug status is a seven-year period of market exclusivity for the indication, if approved.
Mon, Jan. 4, 12:31 PM
- Cytokinetics (CYTK -4.7%) commences a Phase 2 clinical trial assessing CK-2127107 in patients with spinal muscular atrophy (SMA), a severe neuromuscular disorder characterized by progressive muscle weakness resulting in respiratory and mobility impairment. Treatment options are very limited for the condition.
- The double-blind, randomized, placebo-controlled study will enroll 72 SMA patients in two sequential, ascending dose cohorts of 36 subjects. Each cohort will comprised of 18 ambulatory and 18 non-ambulatory patients. The primary objective is the determine the pharmacodynamic effects of a suspension formulation of CK-2127107 following multiple oral doses. According to clinicaltrials,gov, the estimated study completion date is December 2016.
- CK-2127107, under development with Astellas (OTCPK:ALPMF)(OTCPK:ALPMY), is a skeletal muscle troponin activator that slows the rate of calcium release from the regulatory troponin complex of fast skeletal muscle fibers. Calcium triggers muscle contraction.
Nov. 30, 2015, 4:38 PM
- Ironwood Pharmaceuticals (NASDAQ:IRWD) and licensee Astellas Pharma (OTCPK:ALPMF)(OTCPK:ALPMY) announce that a Japan-based Phase 3 clinical trial assessing linaclotide in patients with irritable bowel syndrome with constipation (IBS-C) successfully achieved its two co-primary endpoints. The first, the number of responders as measured by the Global Assessment of Relief of IBS Symptoms compared to placebo, was 34% and 18%, respectively (p<0.001). The second, Complete Spontaneous Bowel Movement Overall Responders also favored linaclotide 35% to 19% (p<0.001).
- Astellas, holder of commercialization rights in Japan, intends to file a new drug application with the Ministry of Health, Labour and Welfare in 2016. Under the terms of the companies' 2009 license agreement, the submission will trigger a $15M milestone payment to Ironwood. Regulatory clearance will trigger a second $15M payment.
- CSO and President of R&D Mark Currie, Ph.D., says, "Linaclotide has now met all primary endpoints in all eight of its Phase 3/3b clinical trials, spanning two indications, three doses and multiple countries. Our recent positive Phase 3 data in China and now Japan represent important achievements by Ironwood and our global partners toward bringing linaclotide to appropriate patients around the world, and we continue to innovate with linaclotide as part of our mission to address a broad spectrum of patient needs."
- Previously: Ironwood earns $15M milestone from Astellas (Nov. 20, 2014)
Company Description
Currently, there's no company description for ALPMF.
Sector: Healthcare
Industry: Drug Related Products
Country: Japan
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Call our experts: 888.808.FINE
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Check Availability(205) 545-7482(888) 550-5733(205) 545-7405
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Apartment Features
- Air Conditioning
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Special Features
- Pets
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- Basketball Court(s)
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- Walking dist. to grocery stores/post office/banks
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Ratings & Reviews
8 Reviews for Chateau Orleans
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I really enjoy living at Chateau Orleans. It is well managed. The apartments are well-maintained inside and outside. I feel safe. Management listens to my concerns. It would be nice to have poolside furniture. Also, the water bills are very high.
As for older complexes, this one is well run, kept clean and tidy, their maintenance is always handled in a timely manner, if they are given notice of the problem. It is located in a great quiet neighborhood that is extremely accessible to shopping, business & schools. It may not have the newest or fanciest amenities, but the rent is appropriate to that. In general, the apartments are on the larger size compared to many.
excellent, efficient and friendly management and staff
Management does care when you call in about a problem. I think their should be
maintenance 24/7 with someone besides just one person on-site.
The one man that is on the property is great if you need his help.
Property maintained, rules are fair ,plenty of parking.
- 1
- 2
What is a Certified Resident?
A resident who lives at the property and has completed a resident satisfaction survey.
Advertising properties provide a list of email addresses of its residents to Kingsley Associates, a third party market research firm, who then sends out the satisfaction survey to the residents. Properties may also conduct satisfaction surveys of its residents through other third party market research firms. In those cases, we will publish those survey responses as long as the questions conform to our standard survey format.
Because reviews are from Certified Residents, and are managed by a third party, you can feel confident that the feedback provided is accurate and trustworthy.
General Directions
Take Highway 280 East past Waterworks on right. Turn left at Green Valley Road in front of the Whole Foods Grocery Store. Go 1 mile, turn left on Asbury Road. We are located 2 blocks up on the right just past the post office. The office is located in front of the tennis courts.


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VIDEO: Where are they now? Catching up with former high school athletes: Ashley Benson
Tue., Jul. 5, 2016
VIDEO: IU Women's Soccer Coach Amy Berbary on the team's 2016 schedule
Tue., May. 31, 2016
VIDEO: IU Women's Soccer Coach Amy Berbary on winning the Herbert Cup
Fri., May. 27, 2016
VIDEO: Off the court with IU Volleyball
Mon., May. 16, 2016
Hoosier Morning: Weekly Roundup
Fri., May. 13, 2016
VIDEO: Off the court with IU Volleyball
Thu., May. 12, 2016
VIDEO: Off the court with IU Volleyball
Tue., May. 10, 2016
Indiana and Duke are just taking the field for warm-ups with the Hoosiers' season opener set to kick off in about 30 minutes.
In the evening's first game, Akron got a goal early in the second half from Kofi Sarkodie, the younger brother of IU's Ofori, then pulled away for a dominating 3-0 victory over Notre Dame. Indiana will play the No. 12 Zips, coached by former IU player and assistant Caleb Porter, Sunday at 2 p.m.
I'll be back with a pre-game update and will update every 15 minutes of game time or as events warrant.
First half kick off
Hoosiers ready to start the season with Chay Cain at goalkeeper, Tommy Meyer/Ofori Sarkodie/Kevin Alston/Daniel Kelly defending, Rich Balchan/Brad Ring/John Mellencamp/Eric Alexander at midfield and Will Bruin/Darren Yeagle at forward.
30:00, first half
Fifteen minutes in and no score. The Blue Devils have had the run of play with 3 shots and 2 corners while IU has yet to get off a shot. Indiana 0, Duke 0
13:00, first half
The score still hasn't changed but the momentum seems to have switched ends as the Hoosiers are starting to apply some offensive pressure. Indiana 0, Duke 0
End of first half
For those of you still awake both inside and outside of Armstrong Stadium, there is still no score. Sometimes in soccer, scoreless is still exciting but this first half does not fall in that category. They'll go to the lockerroom to regroup. Indiana 0, Duke 0
31:55, second half
And just when I was poised to say that the second half was the same as the first with the Hoosier offense a little bit louder and Duke's defense a little worse, we have a goal. Kevin Alston steps up from the back and hits a shot that is deflected past the keeper. Indiana 1, Duke 0
27:00, second half
Offense, we've got offense. Duke will not go away and some miscommunication among IU defenders allows the Blue Devils' Kyle Bethel to poke the ball into the net from point-blank range. Indiana 1, Duke 1
15:00, second half
And now both teams seem to have fallen back into the malaise we were watching earlier. This game seems to lack a real flow. Indiana 1, Duke 1
5:45, second half
Hoosiers break the tie as Brad Ring lays the ball off to John Mellencamp at the top of the box for a shot off the framework into the top right corner. Indiana 2, Duke 1
Indiana hangs on for the victory in the opener. Indiana 2, Duke 1
Read more in Men's Soccer
At least you get to enjoy a nice evening outside.
At least you have windows to look out of.
Thanks for liveblogging!
Go Hoosiers!
I was in a couple of classes with Caleb Porter. He was always a pretty decent, normal guy in real life. He seemed a little, uh… extra exuberant, on the field.
My favorite memory of him as a player was during his freshman year when he sliced up the Cal-State Fullerton defense in the Elite 8 after getting no PT all season long.
I would think Covington has a real opportunity at one of the hybrid po [...]
t, I agree with your assessment but I really do think that in the nex [...]
So far very good recruits. IU must remember that you need one TOP QB i [...]
IU owes Covington a real opportunity! He sacrificed for us when called [...]
Great for Yogi! I watched the Summer League games. If the Coach will a [...]
My point is out of 7 teams in east division 1 or 2 could be top 10, [...]
t, The B1G is getting to be a very tough division and will only get t [...]
Find Notre Dame football coverage on NDInsider.com. © Hoosier Times Inc., all rights reserved.


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Elizabeta Petakovic
Modal header
One fine body…
- Dübendorf, Switzerland
- Work online marketing
- Industry Technology / Software / Internet
- Website www.minicomdigitalsignage.com
- About Minicom Digital Signage is the world leader in advanced multimedia distribution and extension platforms for the digital signage marketplace. The digital out of home industry has come to rely on Minicom's low density CAT5-based hardware systems to deliver high resolution, high performance multimedia content. Today over a quarter of a million screens worldwide run using Minicom technology. Minicom's award winning solutions enable transmitting multimedia content from media player or video server to multiple digital displays located up to 600m away allowing enormous flexibility in screen layout and design as well as placing media players safely in a backroom simplifying service and mainte
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Job Overview
Experience your America and build a fulfilling career by joining the National Park Service. Become a part of our mission to unite our past, our cultures and our special places, to establish important connections to the present and build a rich and lasting legacy for future generations.
This position is located in the Pacific West Regional Office San Francisco, CA United States 1 vacancy
, in the Division of Comptroller and supports the Budget program.
, in the Division of Comptroller and supports the Budget program.
This position has full promotion potential to the GS-06, however it will only be filled at the GS-04 grade level.
This position is being filled under the Pathways Internship Program which is designed to provide students enrolled in a wide variety of educational institutions, from high school to graduate level, with paid work opportunities in agencies to explore federal careers while still in school. Applicants must be current students, enrolled or accepted on at least a half-time basis, and pursuing a degree or certificate in a qualifying education institution (see the Education' section for more information). Interns may be converted to a term, career-conditional or career appointment within 120 days following successful completion of all of their education and work experience requirements. For more information on the Pathways Intern Program, visit: http://www.opm.gov/HiringReform/Pathways.
WHO MAY APPLY: Current students in an accredited high school, college (including 4-year colleges/universities, community colleges, and junior colleges); professional, technical, vocational, and trade school; advanced degree programs; or other qualifying education institutions pursuing a qualifying degree or certificate, in good academic standing (GPA of 2.0 and above).
Government Housing NOT available.
The full promotion potential of this position is: 06
Position Contact:
Maria Davila 415-623-2165
Vacancy Identification Number: 944790
Provides clerical support to the Regional Comptroller's Office. Finalizes correspondence for signature. Serves as timekeeper for the office, inputs time and attendance data using Quicktime. Conducts inventory of property and equipment for the Office. Provides budget support in consolidating, organizing, and processing funding data in National Park Service systems such as Project Management Information System and Operation Formulation System. Provides core financial support in running financial reports and inputting financial data in National Park Service systems such as Administrative Financial System and Financial and Business Management System.


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Easy Learning Mandarin Chinese Characters - Collins Easy Learning Chinese (Paperback)Collins Dictionaries
£9.99 £7.99
Paperback Published: 05/04/2012
- Save £2.00
- In stock
Click & Collect From your local shop
Learn how to write 250 of the commonest Chinese characters, with stroke by stroke guidance on every page. With thousands of characters to learn, beginning to read and write Chinese is a daunting task. Aimed at learners, this book takes you through 250 of the most common characters in a clear and accessible way. The meaning of every character is explained along with information about its radical, the compound words it can form, its history, and more. There is a practice grid on every page, showing how the character is written, with space for you to practise writing the character for yourself. It is generally agreed that learners of Chinese need a working knowledge of about 100 characters in order to make themselves at all understood and to travel in China, so Easy Learning Chinese Characters is a great place to start.
Publisher: HarperCollins Publishers
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Ready in 1h
Try this Steamed Mussels And Scallions in a Cream And Rosemary Sauce recipe, or contribute your own.
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Scrub and de-beard the mussels. Discard any which are broken. If there are any which are open give them a sharp tap on the work surface. If the mollusc is alive it will close of its own accord. Any which remain open are dead and must be discarded. Use a large wide-based shallow saucepan to cook the mussels. Heat the fish stock in the pan until bubbling. Add the mussels in a shallow layer in the pan. Cook them in about 3/4 batches. It is important to cook the molluscs quickly and to remove them from the liquor as soon as the shells open so that they are tender. Overcooking them will toughen them. Using a slotted spoon, remove the opened mussels to a bowl and continue to cook the rest. Remove the meat from the shells and save. Pour the cooking liquor and any liquid in the shells through a fine sieve to remove any grit or bits of shell. This will form the basis of the sauce. Peel and slice the scallions. Peel and finely chop the garlic. Take the leaves from the rosemary stems and chop. Skin, seed and chop the tomato flesh. Pour the mussel liquor into a wide shallow pan and add the cream, chopped garlic and rosemary. Reduce all together to concentrate the flavours and caramelise the cream slightly to give a nutty flavour. Add the scallions and cook in the sauce for a minute or so. Add the tomato flesh and mussels and heat through. Season with lots of freshly ground black pepper, the sugar and a little salt if it is needed. remember that the mussel juices will be salty, so taste first. Serve sprinkled with the freshly chopped chives. DISCLAIMER(c) Copyright 1996 - SelecTV Cable Limited. All rights reserved. Carlton Food Network http://www.cfn.co.uk/
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program to unscramble proper nouns - download fast -=eeDX=-
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Atlas pratique de m�decine manuelle ost�opathiqueElsevier Health Sciences France 2011; US$ 56.99
Les th�rapies manuelles sont aujourd?hui largement utilis�es dans la prise en charge des pathologies douloureuses communes et la m�decine manuelle ost�opathique se pr�sente comme une alternative de choix aux th�rapies m�dicamenteuses dans les pathologies ost�o-articulaires (cervicalgies, dorsalgies, lombalgies). Fort du succ�s... more...
Planning and Positioning in MRIElsevier Health Sciences APAC 2009; US$ 104.00
Positioning in MRI is a clinical manual about the creation of magnetic resonance images. This manual focuses upon patient positioning and image planning. The manual is organised by body region and provides valuable insight into - Patient pathology on MRI. Considerations when positioning both the patient and coil. Imaging planes. Anatomical... more...
CommunicationElsevier Health Sciences APAC 2008; US$ 72.21
This text introduces health sciences students to the various interpersonal communication skills that are commonly used within health settings to establish relationships with clients and fellow professionals, and improve therapeutic outcomes. It focuses on developing self awareness and skills for use in health settings and covers the types of scenarios... more...
Le syndrome neurog�ne douloureux. Du diagnostic au traitement manuel - Tome 1Elsevier Health Sciences France 2012; US$ 60.99
Cet ouvrage est consacr� � la prise en charge manuelle, des syndromes canalaires, dus aux dysfonctions du syst�me nerveux . Il propose un concept original, bas� sur les derniers d�veloppements du management neurodynamique . Chacun des treize chapitres de l�ouvrage, traite d�un conflit particulier au niveau du membre sup�rieur, de la ceinture scapulaire... more...


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Tom Clancy's Endwar
"Win the game, over." Published Tuesday, 17 July 2007
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BOISE, Idaho (AP) - The College of Idaho is trying to ban an app named after the 1950s novelty song, "Yakety Yak," after some students reported being harassed or bullied through the application.
LAS VEGAS (AP) - B.B. King, whose scorching guitar licks and heartfelt vocals made him the idol of generations of musicians and fans while earning him the nickname King of the Blues, died late Thursday at home in Las Vegas. He as 89.
PHILADELPHIA (AP) - In the moment the Amtrak train that derailed at a curve this week was supposed to be slowing down, it was accelerating, investigators said Thursday.
ALLENTOWN, Pa. (AP) - The homicide case against an eighth-grader and her soldier boyfriend, who are accused of conspiring by text message to have her mother killed, was sent to county court for trial Thursday after a hearing in which prosecutors showed photos of the victim.
WASHINGTON (AP) - Like an underachieving student, the U.S. economy isn't living up to the high hopes it began the year with.
ST. LOUIS (AP) - Nearly a century after Sgt. William Shemin pulled wounded comrades to safety on a World War I battlefield, his heroism has finally earned him the nation's highest service medal.
CONCORD, N.H. (AP) - William Shakespeare and Robert Frost made an appearance in the New Hampshire Senate on Thursday as lawmakers approved a measure requiring schools to give parents at least two weeks' notice if a teacher plans to use material related to human sexuality or sexual education that some could consider objectionable.
BOSTON (AP) - Parishioners of the St. Frances Xavier Cabrini Church must end their 11-year protest vigil and vacate the shuttered Roman Catholic church, a Massachusetts judge ruled Thursday.
DENVER (AP) - Colorado is slogging through a wetter than normal spring, with heavy rains restoring much-needed moisture to parched rangeland and sending some rivers over the banks.
NEW YORK (AP) - Carl's Jr. and Hardee's are cramming a summer cookout into one burger.
NEW YORK (AP) - Shoot enough photos and videos, and your phone will eventually fill up.
ROCKFORD, Mich. (AP) - A Michigan couple who already had 12 sons have kept the all-male streak alive with the birth of boy No. 13 on Wednesday.
ATLANTA (AP) - For the first time, a large study suggests that a vitamin might modestly lower the risk of the most common types of skin cancer in people with a history of these relatively harmless yet troublesome growths.
AUSTIN, Texas (AP) - They ask lots of questions that can require patience, they tend to tune out financial arguments - and with Hillary Clinton running for president, more are probably on the way.
HAMILTON, Mont. (AP) - Gunfire that struck a Montana bartender as he carried his injured dog outside his house after a shift likely would have killed him if it didn't hit the pit bull first, the man's brother said this week.
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JANESVILLE, Wis. (AP) - House Speaker Paul Ryan endorsed Donald Trump's bid for president on Thursday, bringing an end to the extraordinary public split between ...
CLEVELAND (AP) - The father of a woman killed by a convicted sex offender dived across a courtroom table to attack him Thursday shortly after a ...
AIR FORCE ACADEMY, Colo. (AP) - The pilot of a U.S. Air Force Thunderbird ejected safely into a Colorado field Thursday, crashing the fighter jet ...
NEW YORK (AP) - Rising drug and alcohol overdoses, suicides, and disease from chronic alcoholism - labeled "deaths of despair" by one expert - are cutting the lives ...
SMYRNA, Tenn. (AP) - A Blue Angels F/A-18 fighter jet crashed Thursday near Nashville, Tennessee, killing the pilot just days before a weekend air show ...
LAS VEGAS (AP) - Parts of the Western U.S. are getting an early taste of scorching summer heat, forcing officials in California, Oregon and desert ...
WASHINGTON (AP) - A close friend of Donald Trump has helped start a super PAC to support him, potentially giving the presumptive Republican presidential nominee his ...
MOUNTAIN VIEW (AP) - Soon, all you'll need to do is Google yourself if you're wondering how deeply Google has been digging into your ...
SAN FRANCISCO (AP) - Uber said Wednesday it is getting a massive cash infusion from Saudi Arabia.
FAYETTEVILLE, Ark. (AP) - Wal-Mart is reviving its yellow smiley image to be the face of its low-price marketing.
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Gerald Young, 72, passed away Sunday, August 4, 2013 at his home in Leavenworth, Kan. He was born on March 30, 1941 to Lawrence Young & Marian Clark Young Sole. He was proceeded in death by his parents, his stepfather, Ernest Sole, three brothers, Leroy, Michael and Lawrence Young, and four sisters, Catherine, Judith, Phyllis Young and Susan Sole. He is survived by his two children, Colony Young of St. Joseph, Mo., Mitchel Young of Texas, a granddaughter, Janiesa Card, great granddaughter, Vivian Card, two brothers, Truman Young of Wis., and Arnold Sole of Leavenworth, Kan. A memorial service will be held Friday, August 16, 2013, 6 to 8 p.m. at Davis Funeral Chapel. Condolences may be sent to www.davisfuneralchapelinc.com. He will be missed by all.
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Girls Soccer: Frostproof Heats Up To Oust Avon Park, 5-0
Published: Monday, January 13, 2014 at 11:04 p.m.
Last Modified: Monday, January 13, 2014 at 11:04 p.m.
FROSTPROOF | Frostproof girls soccer coach Julia Valentine was a bit concerned early when, despite her team dominating the first 10 minutes of the first round of Monday's Class 2A, District 10 contest against Avon Park, the game was scoreless.
After all, the Bulldogs squad has no seniors on the roster and the only junior the team had is injured. But it turns out Valentine didn't have much to worry about.
Freshman Abigail Laureano scored two goals to lead Frostproof to a 5-0 victory over Avon Park in Frostproof.
With the victory, the Bulldogs (6-11-1) advance to today's semifinal contest where they will face top-seeded McKeel. The game, played at Mulberry, takes place at 5:30 p.m.
"We were a little nervous," Valentine said of the early missed opportunities. "But I knew our defense could get back there and cover and reset."
Frostproof's defense didn't have to do much as Avon Park, whose season ends at 0-14, only crossed midfield twice in the opening 20 minutes of the contest and didn't get a shot on goal until the outcome was no longer in doubt.
Meanwhile, Frostproof got its offense going. In addition to Laureano's goals, the Bulldogs got goals by JT Dupuiz, Isabel Aguilar and Perla Vazquez also found the back of the net.
"I think they're starting to get it," Valentine said. "Everything is connecting. Everything is starting to come together."
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Vote for the Bartow Ford Player of the Week for Nov. 27:
|Quayshawn Nealy, Lakeland: Blocked punt, 35-yard INT return for TD
|Justin Shafer, Lake Wales: 204 yards passing, game-winning rush TD
|Ronald Jones, Fort Meade: 258 yards passing, 64 yards rushing
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