text:
Separate names with a comma.
im just waiting for the peach and zelda too hot for tv :D
is it me or can you only do it once a match?
in anime's final wish one fox looks like hes flipping samus off.
"About what he does before they talk - I think that fox is calling them on his wrist communicator, and then he stands up and salutes them. Atleast...
they're just acting like that so they can play while you're handling the customers. :)
your managers dont care if you guys open up the games?
do you guys at TRU and other stores change the games in the machine or is it a nintendo rep who does it?
that would be the longest day of work if i did that. or ill rig the store GC kiosk to play it and sneak a little game during your break :)
maybe nintedno shipped it earlier to make the dec. 3rd date.
there better be enough hotcakes when i try to get mines!!!
why do i need one? if i dont get one my father will beat me! oh god here he comes...hurry!
"I saw a post on the xbox saying on MSNBC that Microsoft were buying some of their own consoles. "
thats kinda stupid since MS looses money for...
"THEY ARE VIDEGAME CHARACTERS. Get a real life girl friend."
do you have a sister?!
"Samus looks like THAT!? Good god, I always imagied her as a Sara Conner look a like but ugly as hell under helmet mask of hers.
Ok, Add Samus to...
yeah, orchid's hot.
no, we still think you're a fool, but we liked the topic.;)
that ED girl's face is kinda manish.
Ms. Pacman!
just take off her head. and on an old electronic gaming monthly mag, they had a samus drawing on the cover with out her helmet.


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The Lady Pride notched nine goals in the first half of Thursday's home Central California Conference showdown against Buhach Colony High, as they held on to secure Pitman's second league win of the season, 12-9.
Buhach Colony played spoiler on Thursday afternoon when they came in to town to take on this year's Pitman High boys' water polo team.
The improvement of the Turlock Christian High varsity football program was evident in Thursday's league opener when the Eagles hosted Sierra Ridge in the Central California Athletic Alliance opener.
The Pitman High varsity volleyball team surpassed another milestone on Wednesday night.
Hilmar has a history of dominating Hughson High on the volleyball court.
If the Hilmar High varsity volleyball team continues to execute their game-plan like they did on Monday night, then the opposing teams are going to find it very difficult during league play to top the Yellowjackets.
The 2015 Turlock High School girls' varsity tennis team is unlike any other team that head coach Linda Bejaran has had in her recent years.
Erica Crain and the 2015 lady Prides' Central California Conference opener was a big success on Thursday when the water polo team hosted Atwater in a lengthy game that went into two extra periods of play.
Atwater High's goalkeeper Vince Baraldi and Connor Norton sank Pitman High's hopes for a win in their league opener at home on Thursday afternoon.
The Central California Conference Cross Country kicked off their league opener at Donnelly Park Wednesday with Turlock and Pitman gunning for the finish line in the first cluster meet.
For the first time since 2009, the Turlock Christian High varsity football team has won two out of their last three games (which includes last season's finale). The Eagles defeated Delta, 50-22, on Friday in the team's home opener.
Pitman boys' soccer fell short to Patterson on Tuesday afternoon as the Tiger's defense did not allow the Pride to score.
Turlock High's varsity volleyball team is starting off undefeated at home this year after a notable performance over Tracy West on Thursday.
Patterson High goalkeeper Carlos Moreno kept the Turlock Bulldogs from claiming their first win of the year in the team's home opener on Tuesday night after a string of superb saves that enabled the Tigers to leave Joe Debely Stadium with a goalless draw.
Coming off a 2-1-1 record in the Pitman Pride Cup this prior weekend, the Hilmar High Yellowjackets were quick to turn the tables after recent back-to-back losses to higher division opponents.
Page 10 of 41
The Little League All-Star season has come to a close for Turlock's American 12-year-olds after Tuesday's loss at the hands of El Dorado ...
It was a dramatic ending to the Mid Valley Swim League Championship Saturday at the Pitman High pool with the Turlock Seadogs skimming through at ...
It took five games in five days, but the Turlock American 12-year-olds are the 2016 Section 6 Champions after the Little League All-Star team battled ...
Tuesday and Wednesday marked the Section 6 final for the Turlock American 11-year-old All-Stars who met Morada at Madison Park in Stockton, but in the ...
The American 10s failed to top Northgate in the Section 6 final on Wednesday, which eventually cost them a banner.
Page 1 of 1
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Hotels near Pioneer Square
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- Most bookedHotel Monaco Seattle, a Kimpton Hotel
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"amenities, service, and pet friendly vibe all welcome and wanted."
k, Jun 2016, US
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"nice hotel, but you get docked when you don't have a coffee maker in the room."
A Traveller, Jun 2016, US
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"The entrance to this hotel is very charming, the lobby is clean and the staff at the front desk is helpful and friendly, and there is a charming cafe and restaurant on the lower levels. First impressions are good. The elevator is small but clean and quick. The hallways are cozy but also very ..."
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"Amazing customer service! Went for my husbands birthday and they had everything taken care of. Super friendly staff, bartenders and managers. Would highly recommend."
A Traveller, Jun 2016, US
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"Decent place overall. It's an old historical hotel right downtown, small lobby, not posh by today's modern standards, but has character. Very reasonably priced and good rooms, clean and comfy."
A Traveller, Jun 2016, US
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"Had two nights here at the end of a long stretch on the road. Staff were excellent and very attentive to my needs and wants. Room was spacious and comfortable. Understated luxury. No surprises in terms of nickel and dime add ons. I will come back to this hotel the next time I am in the Emeral..."
A Traveller, Jun 2016, US
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"the hotel was in a great location. walking distance to pikes place and other attractions. I def recommend staying here."
A Traveller, Jun 2016, US
55 people looked at this hotel in the last hour
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"One night stay in Seattle - hotel very convenient to the light railway system going to/from SeaTac airport. Comfortable hotel with eclectic, old-fashioned decor. Would definitely stay here again."
A Traveller, Jun 2016, CA
45 people looked at this hotel in the last hour
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"Location and view was amazing! Close to everything downtown. Excellent service by Ginosi! Room was not cleaned when we arrived, but they came within an hour to clean, no big deal! They waived our cleaning deposit for the inconvenience. Stayed for 3 nights! Great value, great location-Highly recom..."
A Traveller, Jun 2016, US
6 people looked at this hotel in the last hour
Map of hotels near Pioneer Square
- Pike Place Market
- Space Needle
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- Washington State Convention Center
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- University of Washington
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- Experience Music Project Museum
- Woodland Park Zoo
- Museum of Flight
- Seattle Children's Hospital
- Chateau Ste. Michelle
- Safeco Headquarters
- Fremont
- Alderwood Mall
- Original Starbucks
- University of Washington Medical Center
- Northgate Mall
Hotels in Seattle near Pioneer Square
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Seattle travel guides
Seattle Shopping Guide – where and what to shop and buy
Seattle is a paradise for those who like their shops unique and stylish, and you'll find many boutiq...
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This uniquely Northwest trip in North Cascades National Park is home to rugged beauty few know. Jagged peaks, deep valleys, cascading waterfalls, glacier views, and hanging gardens make for breath…+ More details
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BEST WESTERN Antlers
423 W Main Street, Vernal, UT 84078-2509
Phone: 435/789-1202 | Fax: 435/789-4979 | 44 Rooms
Check Out Time: 11:00 AM | Check In: 3:00 PM | Online Reservations
Welcome to BEST WESTERN Antlers!
The Dinosaur National Monument is located close to our Vernal hotel, and it's a must-see attraction for traveling families.
The oil industry is strong in this area, and we're happy to host oil workers and contractors for extended stays. Our Vernal hotel offers a complimentary, full breakfast buffet to all guests, but it's especially important for oil industry workers to get started on the right note each morning. A hearty breakfast of waffles, sausage, eggs, bacon, fresh fruits, a cereal and yogurt selection, and coffee is just what guests need for a full day of work or play.
Maybe you're here to see the beauty of Flaming Gorge National Park. Whether you're here for the petroglyphs, oil business or a hiking adventure, you deserve a spacious, quiet room to rest up for the fun. We're centrally located on Highway 40, making it easy for guests to zip around the region.
Enjoy spacious rooms that are well-appointed, quiet and welcoming, no matter what brings you to the area. At our Vernal hotel, we have an honest and friendly staff and a home away from home feel.
An outdoor heated pool is available seasonally and is the perfect place to cool off and relax while on vacation. We're centrally located between all the restaurants in Vernal, so a great meal is never far away. Guests who would like recommendations can simply ask any helpful staff member, all of whom are local and ambassadors of the area.
We have many loyal, return customers that have been staying at our Vernal hotel for over 20 years. From extended stays to weekend getaways, our property is ideal for all travelers. Those in the oil industry especially enjoy the superior location and comfortable rooms that are perfect for longer stays.
Reserve your upcoming stay at BEST WESTERN Antlers today for a great value! Enjoy your stay!.
Hotel Amenities & Services
- Exercise facilities
- 100% smoke-free hotel
- Complimentary full breakfast, choice of breads, cereal, fruit, hot eggs, hot breakfast meat, other hot items, yogurt, juice, and coffee
- Outdoor pool Heated seasonal, open May 15th to October 15th each year
- Complimentary breakfast
- Indoor hot tub
- Exercise facility Open from 6:00 a.m. to 10:00 p.m.
- 24-hour front desk. The lobby is open from 6am to 10pm
- Guest laundry,
- Cold weather hook-ups outdoor outlets available for cold weather hook-ups
- Airport courtesy shuttle available 8:00 a.m. to 8:00 p.m.
- Free parking
- Fax services
- Photocopy services
- Business services - Including wireless Internet
- Exterior corridor
- Weight lifting equipment
- Universal gym
- Stationary bike
- Treadmill
- Express check in
- Express check out
- Late check out available upon guest request
- Cable or satellite television
- Free in-room wireless Internet access; All guest rooms are hardwired and offer free wireless Internet access; All guest rooms are hardwired for Internet access
- Ice/vending machines Centrally located ice/vending machine
- Gift shop or newsstand Newstand offering The Salt Lake Tribune
- Additional Truck Parking
- Complimentary coffee and tea
- High-speed Internet access
BEST WESTERN Antlers
Take advantage of the savings and fun with this special offer available at the best western antlers in Vernal.
BEST WESTERN Antlers
Conveniently located, the best western antlers in Vernal, Utah is shown on the map. Detailed driving directions from popular points or nearby cities are listed below. For those with GPS, here you go:
Longitude: 40.455435 / Latitude: -109.536845
Driving Directions to Hotel
From: All directions. The BEST WESTERN Antlers is located on Highways 40 and 191, 33 miles from the Colorado border and 170 miles from Salt Lake City, Utah.
BEST WESTERN Antlers
We care about the quality of your stay with us. Below are nearby attractions, shopping and restaurants that are popular with our guests. Listed locations are nearby with approximate distance listed where available.
Most Popular Area Attractions
Dinosaur National Monument
Dinosaur National Monument
True to its name, the Dinosaur National Monument features exposed fossils of dinosaurs spread throughout the beautiful Unita Mountains near Vernal in northern Utah.
The park's rock layer encloses preserved fossils from the Jurassic Period and offers visitors a glimpse at the remains of over 1,500 bones.
Start at the Dinosaur Quarry Exhibit Hall and marvel at the remains of dinosaurs like the Allosaurus and Stegosaurus amongst the numerous bones.
Afterwards,visit exhibits and colorful murals detailing the dinosaurs' life. Outside, visitors an explore the park's mountain and canyons, encounter wildlife, see ancient Indian petrogylphs, and enjoy stargazing.
Flaming Gorge National Recreation Area
Providing excellent opportunities for boating, fishing, skiing, jet skiing, houseboating and other water sports, the Flaming Gorge National Recreation Area is located in the northeastern corner of Utah, near Vernal.
Steinaker State Park
Home to the Steinaker Reservoir, the Steinaker State Park is set seven miles north of Vernal. One of many lively parks in Utah, Steinaker State Park is an epicenter for fishing, boating, and water sports.
Visitors may set up on the beach, head to the reservoir for swimming and water skiing, or try fishing for largemouth bass and rainbow trout. When in northern Utah, stop by this Utah state park for boating, picnicking, and lounging on the beach.
Utah Field House of Natural History State Park Museum
Founded in 1959, the Utah Field House of Natural History State Park Museum is located in northeastern Utah in Vernal. Covering two acres, this 22,000-square-foot museum focuses on anthropology, geology, and natural history.
Utah Field House visitors may dig for fossils, stroll through the dinosaur garden, and explore the museum. Permanent exhibits include Discover Dinosaurs, Journey Into the Jurassic, Explore the Eocene, and Rocks Revealed.
More Area Attractions & Services
- 0.10 mile(s) from LDS Temple
- 0.60 mile(s) from Dinosaur Museum and gardens and Field House of Natural History
- 0.80 mile(s) from Western Park Convention Center
- 30.00 mile(s) from Ashley National Forest
- 41.00 mile(s) from Flaming Gorge Dam
Local Area Recreation Opportunities
- 2.00 mile(s) from Dina land Golf Course
- Excellent fishing at 2 local lakes
Nearby Restaurants
BEST WESTERN Antlers
Enjoy your stay with us even more by checking out some of the most popular area points of interest and local area events happening in or near Vernal. Chase the links to explore the local region even more.
Local Events Worth Considering:
March 2016
2016 Salt Lake Gallery Stroll
Join Salt Lake City art enthusiasts on the third Friday of every month (except in December when it's the first Friday) for an evening of gallery openings and celebrations of the visual arts. The event is held downtown beginning at 6 p.m.
August 2016
2016 Salt Lake County Fair
All of the classic county fair activities will be found at the Salt Lake County Equestrian Park and Event Center. Admission is free. It all starts at 9 a.m.
2016 Ogden Canyon River Festival
The Mouth of Ogden Canyon at the Rainbow Gardens Centers will be hosting several days of live entertainment, kids' activities, great local food vendors, and tons of outdoor recreation.
August 2016
2016 International Folk Festival
Local and regional folk music acts will perform at the Sandy Amphitheater, starting at 8 p.m. Even better, this event is free of admission. Come get folksy with Sandy residents.
8th Annual Craft Lake DIY Festival
The Gallivan Center in SLC is just about ready to host this annual get together, set to include tons of locally crafted unique gifts and goods, and opportunities to create your wares.
Alberta | British Columbia | Manitoba | New Brunswick | Nova Scotia | Ontario | Prince Edward Island | Quebec | Saskatchewan | Yukon | Caribbean


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Human immunodeficiency virus (HIV)-infected persons taking highly active antiretroviral therapy (HAART) may have an increased risk for cardiovascular-related events, although the underlying mechanism remains unclear. We tested the hypothesis that carotid arterial stiffness was higher among persons taking HAART compared to HAART-naïve and HIV-uninfected persons.
Between 2004 and 2006, we performed high resolution B-mode ultrasound on 2,789 HIV-infected and HIV-uninfected participants of the Women's Interagency HIV Study (WIHS; 1865 women) and the Multicenter AIDS Cohort Study (MACS; 924 men) and determined carotid arterial distensibility, a direct measure of carotid arterial stiffness. We used generalized estimating equations to evaluate the association between distensibility and HIV infection, CD4+ cell count, and exposure to HAART adjusted for demographic, behavioral, and clinical characteristics.
In multivariable analysis, distensibility was 4.3% lower (95% confidence interval (CI): -7.4% to -1.1%) among HIV-infected versus uninfected participants. Among HIV-infected participants with fewer than 200 CD4+ cells, distensibility was 10.5% lower (95% CI: -14.5% to -6.2%) than that among HIV-uninfected participants, and this effect did not differ significantly by cohort or race. Concurrent HAART use was independently associated with lower distensibility among MACS participants but not among WIHS participants.
Our finding that advanced HIV-related immunosuppression was associated with increased carotid arterial stiffness independent from the effects of traditional atherosclerosis risk factors suggests that the etiologic mechanism underlying reports of an increased cardiovascular disease risk among HIV-infected individuals might involve HIV-related immunosuppression leading to vascular dysfunction and arterial stiffening.
The benefits of highly active anti-retroviral therapy (HAART) for treating human immunodeficiency virus (HIV) infection are well established,1, 2 but there is mounting evidence that HAART may also be linked to an increased risk of cardiovascular disease. Protease inhibitor (PI)-based HAART appears to be associated with an increased risk of myocardial infarction (MI)3, perhaps from increased levels of atherosclerosis.4 Several risk factors for atherosclerosis including hyperglycemia, diabetes, hypertension, and dyslipidemia have been reported to be more common in persons infected with HIV, especially among those taking PI-containing HAART regimens.4-8 However, the relationship of HIV and HAART with cardiovascular disease is not clear. Data from the Strategies for Management of Antiretroviral Therapy (SMART) trial suggest that in comparison to HIV-infected patients managed using a drug conservation strategy, those receiving uninterrupted antiretroviral treatment had a lower risk of vascular events despite their sustained exposure to HAART.9 Furthermore, a large cohort study recently found that HIV and HAART were not associated with an increased rate of cardiovascular events,10 and carotid intima-media thickness (cIMT) has not consistently been found to be associated with HIV infection or HAART use.11, 12
We previously reported that systolic hypertension, but not diastolic hypertension, was increased with longer HAART exposure 13. These findings suggest that the vascular effect of HAART may involve the "sclerosis" component of atherosclerosis that is measured by the stiffness of the arteries14 which, itself, is only weakly correlated with cIMT15 and can predict cardiovascular events and death.16 The current study of over 2,700 men and women was designed to investigate the association of HIV infection and HAART use with arterial stiffness using measurements of common carotid artery diameter change over the cardiac cycle.
This cross-sectional study included baseline data from HIV-infected and HIV-uninfected participants enrolled in the Carotid Ultrasound Substudy of the Multicenter AIDS Cohort Study (MACS) and the Women's Interagency HIV Cohort Study (WIHS). MACS and WIHS are ongoing observational HIV cohort studies comprised of 6,972 men and 3,766 women, respectively, in selected metropolitan areas across the United States. Recruitment and follow-up procedures have been reported previously.17-20
Between April 2004 and March 2006, 1,865 women and 924 men received a baseline carotid ultrasound examination.21 Briefly, all WIHS participants who attended a study visit during this time period were eligible for this substudy, while MACS participants attending a study visit during this calendar period were eligible if they were at least 40 years old, weighed less than 300 pounds, and had no prior history of cardiovascular disease. Among WIHS participants, 84 (4.5%) reported a history of MI, congestive heart failure, or stroke. All participants gave written informed consent prior to enrollment, and this study was approved by the Institutional Review Boards at each of the MACS and WIHS institutions.
High resolution B-mode ultrasound was used to image the right common carotid artery (CCA), internal carotid artery, and carotid bulb as previously described.22 Sonographers at each of the WIHS and MACS sites were trained at the University of Southern California Atherosclerosis Research Unit Core Imaging and Reading Center (CIRC), and all scans were centrally read at the CIRC. The ultrasound assessment included measurements of the right CCA diameter at systole (DS) and diastole (DD), and pulse pressure (PP) was measured at the brachial artery. Using these measurements, we quantified carotid artery stiffness using the following index of carotid distensibility,
where lower values reflect a stiffer carotid artery. Distensibility was standardized to the units reported by Lage, et al., (10-6 * Newtons-1 * meters2).23
HIV infection was determined via serologic testing on specimens obtained at each MACS or WIHS study visit using enzyme-linked immunosorbent assays and confirmed using Western blot assays.17, 19 Anti-retroviral therapy use was documented via self-report. Following the DHHS/Kaiser Panel24 guidelines, we defined HAART as the reported use of three or more antiretroviral medications, one of which has to be a PI, an NNRTI, one of the NRTIs abacavir or tenofovir, an integrase inhibitor, or an entry inhibitor. HAART exposure was categorized three ways for analysis: taking versus not taking HAART, PI-based versus non-PI-based HAART, and duration of HAART exposure. Other characteristics included in this analysis were demographic/behavioral factors (e.g., age, race, smoking history), clinical factors associated with atherosclerosis (e.g., cholesterol, body mass index), and degree of HIV immunosuppression (e.g., CD4+ cell count).
We characterized the study population using graphical displays of the data and descriptive statistics (e.g., median, inter-quartile range (IQR)), and the characteristics of the MACS and WIHS cohorts were compared using a chi-square test of association. All statistical comparisons of distensibility were performed using generalized estimating equations25 (GEE) to account for clustering within the 10 MACS and WIHS sites. Multiple regression analyses were performed for the entire study population and then separately for the MACS and WIHS cohorts. Distensibility was natural log transformed to account for its skewed distribution and the model results are reported as the percent difference (PD) in distensibility between those with and those without the corresponding covariate. While approximately 90% of participants had complete data for all study variables other than fasting glucose, we used multiple-imputation26 to account for missing data in the multiple regression models. Statistical significance was defined as a two-sided p-value less than 0.05. All statistical analyses were performed using SAS 9.2 (SAS Institute, Cary, NC, USA).
The characteristics of the 2,789 study participants are shown in Table 1; two-thirds were from the WIHS, the median age was 44.3 years (range 20.2-83.0), and 48% were African-American. More than one-half of the participants were overweight or obese (body mass index (BMI) > 25), 21% had low-density lipoprotein-cholesterol (LDL-c) greater than 3.38 mmol/L (130 mg/dl), 30% had high-density lipoprotein-cholesterol (HDL-c) lower than 1.04 mmol/L (40 mg/dl), and 11% had systolic blood pressure (SBP) above 140 mmHg. Diabetes mellitus (DM) was documented in 16% of participants, but only 5% of those who were fasting at the time of the study visit had a fasting glucose level > 6.94 mmol/L (125 mg/dl). Approximately two-thirds (69%) of participants were infected with HIV, among whom 13% had a CD4+ cell count less than 200 (cells/ml) and 70% were taking HAART at the time of the ultrasound examination.
In addition to the gender difference between the MACS and WIHS cohorts, the distributions of all other characteristics included in Table 1 differed significantly between the cohorts except diabetes, fasting glucose, and the duration of HAART exposure among those who were taking HAART at the time of the examination. Compared to HIV-uninfected participants, those infected with HIV were significantly less likely to have education beyond high school, more likely to have a history of injection drug use (IDU), more likely to have a family history of MI, and had significantly lower BMI, LDL-c, and SBP levels (data not shown).
Overall, the median carotid distensibility was 16.8 × 10-6N-1m2, and the relationship between distensibility and age was similar in the two cohorts (Figure 1). In univariate analyses, distensibility was significantly associated with age, race/ethnicity, history of injection drug use, family history of MI, and all the clinical characteristics included in Table 1. Distensibility was also significantly lower among persons infected with HIV and among current HAART users who had initiated HAART more than 5 years earlier.
HIV infection remained significantly associated with lower distensibility (PD -4.3, 95% CI -7.4 to -1.1) in the multiple regression analysis (Table 2). The effect of HIV was greater in the MACS (PD -5.5) than in the WIHS (PD -1.9), but the difference between the cohorts was not statistically significant (p-value for interaction 0.24). Other characteristics that were independently associated with lower distensibility in this model were older age, African-American and Hispanic race/ethnicity, higher BMI, higher LDL-c, lower HDL-c, and higher SBP. We then added covariates for the use of blood pressure medications and cholesterol lowering medications to the regression models, but these cofactors were not independently associated with distensibility (data not shown) and their inclusion did not alter any inferences drawn from the results in Table 2.
To examine the association between HIV-related immunosuppression and distensibility, we stratified the HIV infected subgroup by CD4+ cell count. HIV-infected participants with fewer than 200 CD4+ cells had significantly less distensible carotid arteries (PD -10.5, 95% CI -14.5 to -6.2) (Table 3, model 1) compared to those who were not infected with HIV, and the association between advanced HIV-related immunosuppression and distensibility did not differ significantly between MACS (PD -6.9) and WIHS (PD -9.2) (p-value for interaction 0.46) or between African-Americans (PD -9.9) and non-African-Americans (PD -9.5) (p-value for interaction 0.42).
Among the 1931 HIV-infected participants, distensibility was significantly lower among those taking HAART in the MACS (PD -4.2, 95% CI -7.0 to -1.4), but not in the WIHS or in the overall model (Table 3, model 2). Among the 1317 HAART users, distensibility was also significantly lower in MACS participants who had been taking HAART for more than 5 years (PD -4.6, 95% CI -8.5 to -0.6), but duration of HAART use was not significantly associated with distensibility in the WIHS or overall models (Table 3, model 3). Finally, distensibility was similar among participants taking PI-based and non-PI-based HAART regimens (Table 3, model 4).
In this study, the largest study of the association between HIV disease and arterial stiffness performed to date, carotid arterial distensibility was significantly lower in HIV-infected versus HIV-uninfected participants after adjusting for the demographic, behavioral, and clinical characteristics of the study population. Distensibility was lowest among HIV-infected participants with advanced HIV-related immunosuppression, and this was true for both MACS and WIHS participants and for both African Americans and non-African Americans. Distensibility was also significantly lower among HIV-infected HAART users in MACS, especially among men who had initiated HAART more than 5 years earlier, but it was not associated with HAART use in the WIHS nor did it differ between those taking PI-containing versus non-PI-containing HAART regimens in either cohort. Thus, our study provides stronger support for an effect of HIV-related immunosuppression, compared to that of HAART, on carotid distensiblity.
Much of the research linking HIV disease with cardiovascular disease has focused on the effects of HIV therapy on metabolic-related factors such as hyperglycemia, insulin resistance, dyslipidemia, and fat redistribution which contribute to arterial disease 8, 27, 28 and may account for some of the increased risk of cardiovascular disease observed among HIV-infected persons taking HAART.4, 29, 30 However, if these factors were to mediate the association between HIV disease and atherosclerosis, then we would have expected that adjusting for them would nullify the association between HIV and distensibility in our analysis; this was not the case. Moreover, BMI, LDL-c, HDL-c, and SBP were all independently associated with distensibility in the expected direction which supports the validity of our results.
Arterial stiffness is associated with impaired endothelial function,31 and it has been proposed that HIV may affect the vasculature directly via endothelial damage,32 promoting arterial stiffness33-35 and contributing to atherogenesis.36 Consistent with this hypothesis, HIV infection was associated with increased arterial stiffness among children.37 The ACTG 5152s study group reported that initiating antiretroviral treatment improves endothelial reactivity, with a direct correlation between the improvement in vascular function and the viral and immunologic response to therapy.38 Data from the SMART trial suggest that, in terms of vascular disease, the risks associated with occasional adverse metabolic effects of antiretroviral therapies may be outweighed by the benefits of maintaining good immunologic function.9 A prior study from our group found that advanced HIV-related immunosuppression was independently associated with an increased prevalence of carotid lesions but not with cIMT.21 Together with our results, these findings suggest that the etiologic pathway connecting HIV infection to arterial stiffness may directly involve HIV-related immunosuppression rather than, or in addition to, antiretroviral therapy and atherosclerosis risk factors. However, caution is urged when interpreting our data because CD4+ cell count was a marker of the immunological status at the time of the ultrasound evaluation while arterial stiffness may stem from multiple processes operating over many years.39
Our finding that HAART was associated with increased carotid artery stiffness in the MACS and that stiffness increased with prolonged HAART use is consistent with our previous MACS study13 in which men who had prolonged exposure to HAART had a higher prevalence of systolic hypertension. It is unclear, however, why this association existed only among the MACS participants in the current study. While the effect of antiretroviral therapies on the vasculature might differ between men and women, it is also possible that differences in the course or treatment of HIV infection between the MACS and WIHS cohorts or, more generally, between men and women40 may have led to these results. Nevertheless, in comparison to HIV-related immunosuppression, HAART was not as strongly or consistently associated with increased carotid stiffness.
The strengths of the current study include the large sample size, being nested within two ongoing HIV cohorts, and the analysis of standardized data from ten different sites. The primary limitation of our study was its cross-sectional design that made it impossible for us to tease apart the etiological importance of HIV-related immunosuppression versus therapy, to describe changes in arterial stiffness across time, or to evaluate the effect of increased stiffness on cardiovascular outcomes. Finally, the unique demographic and clinical characteristics of the MACS and WIHS participants must be considered when interpreting the results from this study.
HIV-related immunosuppression was associated with increased carotid stiffness among both MACS and WIHS participants, while HAART use was associated with carotid stiffness among the MACS participants only. The mechanisms underlying these findings remain unknown, but these results suggest that the etiologic pathways may be independent from traditional atherosclerosis risk factors. Our study contributes to a growing volume of research supporting the hypothesis that HIV-related immunosuppression impacts the risk of cardiovascular disease and underscores the need for further exploration of cardiovascular disease risk among persons infected with HIV.
Data in this manuscript were collected by the Multicenter AIDS Cohort Study (MACS) and the Women's Interagency HIV Study (WIHS) Collaborative Study Group with centers (Principal Investigators) located at the following institutions:
MACS centers: The Johns Hopkins Bloomberg School of Public Health (Joseph B. Margolick, Lisa P. Jacobson), Howard Brown Health Center, Feinberg School of Medicine, Northwestern University, and Cook County Bureau of Health Services (John P. Phair, Steven M. Wolinsky), University of California, Los Angeles (Roger Detels), and University of Pittsburgh (Charles R. Rinaldo).
WIHS centers: New York City/Bronx Consortium (Kathryn Anastos); Brooklyn, NY (Howard Minkoff); Washington DC, Metropolitan Consortium (Mary Young); The Connie Wofsy Study Consortium of Northern California (Ruth Greenblatt); Los Angeles County/Southern California Consortium (Alexandra Levine); Chicago Consortium (Mardge Cohen); Data Coordinating Center (Stephen Gange).
Funding Sources: The MACS is funded by the National Institute of Allergy and Infectious Diseases, with additional supplemental funding from the National Cancer Institute. UO1-AI-35042, 5-MO1-RR-00052 (GCRC), UO1-AI-35043, UO1-AI-35039, UO1-AI-35040, UO1-AI-35041.
The WIHS is funded by the National Institute of Allergy and Infectious Diseases (UO1-AI-35004, UO1-AI-31834, UO1-AI-34994, UO1-AI-34989, UO1-AI-34993, and UO1-AI-42590) and by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (UO1-HD-32632). The study is co- funded by the National Cancer Institute, the National Institute on Drug Abuse, and the National Institute on Deafness and Other Communication Disorders. Funding is also provided by the National Center for Research Resources (UCSF-CTSI Grant Number UL1 RR024131).
This project was also funded, in part, by grants from the National Heart, Lung, and Blood Institute (1R01HL083760-04 and 5R01HL095140-03) to RK.
Conflicts of interest/disclosures: J.P. is a consultant to Pfizer. We have no other disclosures.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


text:
|Reviews for The Goddess of Never Being Broken
| Pamela whitney chapter 1 . 7/16
Breathtakingly beautiful
| FoxLittleRedFox chapter 1 . 7/6
Dear Author,
I've read this story about a year ago, for the first time. It was one of the first stories I have ever read. I didn't leave a review then. I'm sorry.
I've grown as a reader since, learnt proper etiquette at last.
I discovered your story again today and I found it even more beautiful then before. After reading so many others, I can say it's standing out.
It brings a sense of calmness. As I read, I feel as it washes over me...maybe it's the contact with nature and the rain...
I can feel their pain and suffering, but there is love weaved through it. And in the end there is more love, than anything else. I love it.
Thank you
Fox xx
I found some plant names you've used -dittany and wolfsbane. As a florist i realise, they are plant names, but I think it will be confusing to less knowledgeable reader. As you know, in HP world, these names are used for well known potions.
| Hikorichan chapter 1 . 6/9
This was so beautiful. Thank you for writing and sharing.
| Nocturnus chapter 1 . 6/8
| Nocturnal2015 chapter 1 . 5/2
Really the most BEAUTIFUL story I've ever read!
You are a really very good and awesome writer!
I loved this story very much.
| CynthiaER chapter 1 . 5/1
A beautifully written story that perfectly sums up Severus' life as well as the experience of all human lives. We cannot avoid suffering, often times it is unexplainable and unfair, yet it can make us more powerful than we ever were. This story encapsulates that message while being a touching narrative of love. Thank you so much for writing this lovely piece.
| cloudshape to ennien chapter 1 . 4/30
Finally a happy ending. You have just made me incredibly happy with this story. It is so warm and wonderful and I just love to know, that Severus and Hermione are happy now.
| Mystical G Panther chapter 1 . 2/7
| meg527 chapter 1 . 1/24
Wow! I love this! Thank you!
| lena1987 chapter 1 . 12/31/2015
This is absolutely stunning. Thank you for sharing this with us. I wish I had the words to explain just how much it meant to me. Alas I do not, and so I shall simply say that you have created something very, very beautiful here.
| memomemo chapter 1 . 12/20/2015
continue please
| Guest chapter 1 . 10/13/2015
amazing :)
| Guest chapter 1 . 9/26/2015
And there it is ladies and gentleman. The treatment to whatever the hell was wrong with Snape was sex. :P
| MyLovelyHorse chapter 1 . 8/13/2015
You leave my heart and soul just ragged with your beautiful writing - a quivering pile of tears and snot and painful happiness - I mean this in the best possible way. And I've just reread this for the umpteenth time. You pack more in under 10,000 words than most writers can manage in five times that amount. I have only read a few of your stories because I have to pace myself - they are too delicious to not be savored or rushed. You are a marvel. Merci mille fois.
| TagathaC chapter 1 . 6/30/2015
OH GOD, that was beautiful. Your writing is poetic and moved me SO much. The pacing was exquisite and the breakdown/breakthrough at the end blew me away. Thank you SO MUCH for writing this story. (I wanted it to never end...)


text:
Flash template modify
This project was awarded to dasilva1 for $50 USD.Get free quotes for a project like this
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Project Budget$30 - $50 USD
Total Bids4
Project Description
Hi There,
The template is a flash xml template can bee seen @ [url removed, login to view]
These changes I need:
Mp3 player must play random song on each load(must shuffle)
My image gallery-under merchandise we will be selling some products, so i need them to be able to buy the item(maybe a buy now button)
I have a xml flash guestbook under guestbook ,this must load to in the website-source file will be given
i have a Facebook like box swf ,this must load in the website-source file will be provided.
I need for my video gallery,i would need to add youtube linkage [url removed, login to view] the xml file i want to add youtube links.
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Michael Jordan hated this Air Jordan 10. Here's why. by SneakerNews
Ultimate Guide to the Air Jordan 11 Space Jam 2016 Release
June 14, 2016 BY Patrick Johnson / 4.63 / 5
Last Updated: July 13th, 2016 Jordan Brand's Holiday releases are always some of the most sought after sneakers of that year, and 2016 looks to be no different thanks to the retr...Read More
Best Look Yet At The Air Jordan 11 "Space Jam"
June 9, 2016 BY Patrick Johnson / 4.57 / 5
This December's Air Jordan 11 "Space Jam" is shaping up to be the defacto release of Jordan Brand's 2016 for a number of reasons. The remastering process has t...Read More
Why The Upcoming Air Jordan 11 Release Should Not Be Called "Space Jam"
May 31, 2016 BY Sneaker News / 3.93 / 5
The all-black Air Jordan XI with the icy soles and hits of royal blue will always be called the "Space Jam", as it is commonly connected with the 1996 movie that featured M...Read More
- $525.00 BUY IT NOW 0hr 26mins
- $560.00 BUY IT NOW 2hr 40mins
- $750.00 BUY IT NOW 4hr 47mins
- $168.35 35 bids 5hr 54mins
Air Jordan 11 "Space Jam" Release Date
May 31, 2016 BY Patrick Johnson / 4.22 / 5
The Air Jordan 11 "Space Jam" is returning this holiday season with a number of OG upgrades ranging from the classic '45' PE heel stitching to additional Nike ...Read More
Air Jordan 11 "Space Jam" Made To Look Like The 1995 Original
May 30, 2016 BY Sneaker News / 3.62 / 5
The Air Jordan 11 "Space Jam" is set to make a return this December, and today we get the best look yet at what's shaping up to be one of the best Jordan releases of ...Read More
The Air Jordan 11 "Space Jam" Will Feature Nike Air On The Insoles
May 27, 2016 BY Patrick Johnson / 4.26 / 5
The Air Jordan 11 "Space Jam" is back this December championing a new '45' heel branding in an homage to Michael Jordan's first return from retirement. T...Read More
Air Jordan 11 "Space Jam" To Feature 45 On Heel
May 22, 2016 BY John Kim / 4.5 / 5
You may believe that the Air Jordan 11 had always featured the number 23 on the heel of the shoe. However, the first-ever Air Jordan 11 that was ever revealed to the public featured M...Read More
Air Jordan 11 "Space Jam" Releasing December 2016
February 24, 2016 BY John Kim / 4.67 / 5
It's only February, but better get your Holiday season spending in order because Jordan Brand has not one, but two must-have Retro releases in the works this winter. Along with t...Read More
First Look At The Air Jordan 11 "Space Jam"
January 20, 2016 BY Sneaker News / 4.7 / 5
Earlier this year, we predicted that Jordan Brand would celebrate the 20th Anniversary of Space Jam with a re-release of the classic Air Jordan 11 that was laced up by MJ in that film....Read More
Black Friday vs. December Holiday – Battle Of The Air Jordan Release Traditions
July 8, 2014 BY John Kim / 3.91 / 5
The final two months of the calendar year are always the most exciting for Air Jordan fanatics. Traditions have emerged in recent years that have trained us to expect certain sneaker ...Read More
Best of #SneakerNews – Air Jordan 11s
April 21, 2014 BY Brendan Dunne / 4.75 / 5
The Air Jordan 11 is always bound to cause a stir when it shows up at retail. That was especially true this past weekend, one not one but two Air Jordan 11 Lows released (That would be...Read More
Is It Worth It? A Look Back at Crazy Sneaker Releases and Campouts
April 3, 2014 BY John Kim / 3.64 / 5
In preparation of today's in-store release of the Supreme Foamposites, hordes of sneakerheads and brand loyalists gathered at the store locations in New York and Los Angeles wit...Read More
Original vs. Future: Comparing Tinker's Air Jordan 11 Designs
March 10, 2014 BY Brendan Dunne / 4 / 5
All sneakerheads need is a passing glance at the new Jordan Future to be able to recognize the Air Jordan XI DNA therein. Yes the sneaker borrows the bottoms from Tinker's AJ 11 ...Read More
"Space Jams" for Derek Jeter – A Look at a Rare Air Jordan 11 PE
February 11, 2014 BY Brendan Dunne / 4.83 / 5
There is no doubt that the "Space Jam" Jordan 11 is up there in terms of most celebrated Air Jordans of all time. The sneakers of course get their title from the movie of ...Read More
NBA Feet: Weekend Recap – 12/20 – 12/22
December 23, 2013 BY Patrick Johnson / 0 / 5
Teams continue to prep for the annual NBA Showcase on Christmas Day (a big one for some debuts of silhouettes) but this weekend had plenty to offer in the footwear department. Paul Geo...Read More


text:
Disabling change of password
I am a new Basis administrator. I need to know if a parameter or transaction exists that allows me to avoid that...
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the password of some users can be changed.
I'm afraid such parameter does not exist. You can, however, set a global system parameter that does not prompt the users to change their password ever. But, other than that any regular user can change it at least once a day upon logon.
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text:
HourlyMore than 30 hrs/week
Intermediate Level
Start DateAugust 22, 2013
I am looking for a full time Virtual Assistant in the Philippines. The selected provider should be available between 9am and 16pm Netherlands Time, from Monday-Friday. Please do not bid if you cannot work at home as this job requires you to be online.
You will work for a -becoming famous- (jazz) musician, doing the following tasks:
*Social Media Marketing
*Web research
*Data Entry
*Email response handling
*Calling people to promote me
*Organizing concerts, events, tours, travel.
Job Requirements:
*Must be available 7 hours a day and must have a working computer with internet and headset.
*Must have good communication skills over the phone
*Preferably like my music - check www.bramstadhouders.nl
*Preferably have experience with social media networks - facebook, twitter, linkedin
*Able to do web research on selected topics
*Must know how to make reports on a daily basis via Google Docs
The job will start with a 2 week trial period to see how well you accomplish the first few tasks. I will not choose an assistant who has other commitments.
My budget for you is $2 an hour (1.80 for you), but you will get high bonusses if you do good work and create opportunities.
Include the word "music" at beginning of your bid to let me know you read the job requirements.
I look forward to interviewing you.
Activity on this Job
Last Viewed by Client: 2 years ago
Hired: 3
About the Client
Tilburg 02:18 PM
Jobs Posted
75% Hire Rate, 1 Open Job
Total Spent
22 Hires, 2 Active
Avg Hourly Rate Paid
471 Hours


text:
Marilyn Manson Dominated Rock on the Range! [Gallery]
Just a couple of days ago, Marilyn Manson dominated the Orbit Room.
Just a few days later, the shock rocker rocked MAPFRE stadium!
Just a couple of days ago, Marilyn Manson dominated the Orbit Room.
Just a few days later, the shock rocker rocked MAPFRE stadium!
We warned you, and you hesitated.
Maybe you were lucky and bought tickets, or maybe you weren't.
Either way, tickets are gone!
Planning on getting tickets to the Marilyn Manson show at the Orbit Room on May 13?
You better act now! Not in like 10 minutes, I talking now!
There is only a single digit amount of tickets left to the show!
There's never a lack of strange facts when it comes to Marilyn Manson, but we've dug some stuff up for this latest episode of You Think You Know Metal?.
All sorts of concerts are coming to Grand Rapids this month!
Marilyn Manson, Chevelle, The Used, and more!
How can you win tickets for free? Through WGRD of course!
Planning on seeing Marilyn Manson on May 13 at the Orbit Room?
Better make a decision quickly, because it is about to sell out!
Rock on the Range is just over a month away! Over 50 bands are set to rock Mapfre Stadium in Columbus, Ohio, May 15-17.
The organizers are helping you get a jump on planning your ROTR 2015 experience by releasing the daily lineups for this year's event.
Billy Corgan and Marilyn Manson answered questions from Reddit users about everything from their upcoming "The End Times" tour, to how they've influenced each other musically and why they think a cat should be president.
Marilyn Manson and Smashing Pumpkins will team up for "The End Times" co-headlining trek this summer.
Actor Michael Kenneth Williams captivated audiences as the shotgun-wielding Omar in 'The Wire' and just finished up a run as Chalky White on 'Boardwalk Empire.'
You know, I guess I've never really thought about Marilyn Manson's family. I assumed that he had one, but I never guessed that his dad would be as eccentric and outgoing as his son!
Turns out he is, though, and we get a glimpse into that in a new photo shoot for Paper Magazine.
Marilyn Manson spoke about tension between himself and Billy Corgan, which began with a letter Corgan sent about Manson's then-girlfriend Rose McGowan.


text:
SUSE Linux Enterprise 12 Debuts With 'Rock-Solid' Cloud SupportSubmitted by Rianne Schestowitz on Monday 27th of October 2014 05:08:48 PM Filed under
After more than five years of development, SUSE on Monday rolled out SUSE Linux Enterprise 12, a brand-new version of the enterprise-class edition of its popular Linux platform. Built for reliability, scalability and security, the new release is designed to help companies efficiently deploy and manage highly available IT services in physical, virtual or cloud infrastructures.
SUSE Linux Enterprise 12 serves as the foundation for all SUSE data center operating systems and extensions. New operating systems and software extensions based on it include SUSE Linux Enterprise Server for x86_64, IBM Power Systems and IBM System z; SUSE Linux Enterprise High Availability Extension and Geo Clustering for SUSE Linux Enterprise High Availability Extension; SUSE Linux Enterprise Virtual Machine Driver Pack; and SUSE Linux Enterprise Desktop and SUSE Linux Enterprise Workstation Extension.
openSUSE Factory to merge with TumbleweedSubmitted by Rianne Schestowitz on Monday 27th of October 2014 09:07:40 AM Filed under
As a long-time openSUSE I wondered about the future of Factory and Tumbleweed when the project announced Factory's evolution as an independent rolling release of the distribution.
Tumbleweed maintainer and the lead Linux kernel developer Greg Kroah-Hartman was not very positive about the future of Tumbleweed, which was considered to be a 'kind-of' rolling release version.
Back then Ludwig Nussel of openSUSE told me, "The new Factory is not here to replace Tumbleweed. Both rolling distributions accomplish different goals. The Tumbleweed initiative provides rolling updates of selected packages (~10% of the packages in Factory) on top of the most recent openSUSE released version. Tumbleweed therefore always has openSUSE releases as base. Factory on the other hand is a full rolling distribution where all packages, even core ones are continuously updated and rebuilt."
Tumbleweed, Factory rolling releases to mergeSubmitted by Rianne Schestowitz on Friday 24th of October 2014 12:23:01 PM Filed under
"With the release of openSUSE 13.2 due in November, we realised this was a perfect opportunity to merge our two openSUSE rolling-releases together so users of Tumbleweed can benefit from the developments to our Factory development process over the last few years," said Richard Brown, Chairman of openSUSE board. "The combined feedback and contributions from our combined Tumbleweed and Factory users should help keep openSUSE rolling forward even faster, while offering our users the latest and greatest applications on a stable rolling release."
Coming Attractions: Makulu, openSuSE and Fedora releases on the waySubmitted by Rianne Schestowitz on Wednesday 22nd of October 2014 03:14:41 PM Filed under
Makulu Linux Cinnamon Debian Edition. Whew, that's a mouthfull, isn't it? I have said before that Makulu is my favorite distribution for the pure joy of Linux. Full of great graphics, bells and whistles galore, and overflowing with pretty much every package, application or utility you can imagine. The final release of this version is due out next Monday, 27 October, barring unexpected obstacles.
Linux clusters in German finance ministry data centreSubmitted by Rianne Schestowitz on Wednesday 15th of October 2014 09:42:34 AM Filed under
The shared IT service centre for Germany's federal government (ZIVIT) has awarded a 10 million euro support contract for open source software, it announced on 8 October. The four-year contract was won by CGI, a large ICT service provider. The contract is for maintenance and management of a high availability Linux cluster running databases, file and network services and backups systems, used by the Federal Ministry of Finance.
openSUSE 13.2 RC1 is now out, hands onSubmitted by Rianne Schestowitz on Thursday 9th of October 2014 12:29:00 PM Filed under
openSUSE 13.2 RC1 is baked and ready to serve!. This previous Beta release was a blast with almost 10.000 downloads. The community responded to the call and we had lot of eyes looking for bugs in openSUSE 13.2 Beta1. Many of them have been already squashed and openSUSE 13.2 Release Candidate 1 is here to prove it.
Mark Shuttleworth, The State and Ubuntu 2.0Submitted by Roy Schestowitz on Wednesday 8th of October 2014 12:47:41 AM Filed under
Shuttleworth's Ubuntu is an open source software with limited proprietary components, meaning that users are encouraged to upload it, improve it, upload those improvements, and make the world—or, rather, the computer—a better place. Once, back when these things were discussed by men with nicotine-stained fingers and furtive eyes, open source promised to be the keystone in a shared economy ushered in by the digital revolution. Open source too often fell in a paradoxical grey zone—software created by a billionaire who lives on an island of money is not exactly the stuff of utopian dreams. But that shouldn't detract from the fact that it once offered very real possibilities. Sadly, the digital revolution was thoroughly co-opted by non-visionaries like Bill Gates, a man so boring he made a fucking office out of pixels, and those who helped turn the Internet into a one-click shopping mall.
SUSE, MariaDB and IBM team up to tame Big DataSubmitted by Roy Schestowitz on Wednesday 8th of October 2014 12:40:58 AM Filed under
SUSE and MariaDB (the company formerly known as SkySQL!) officially teamed up today, joining forces with IBM Power Systems, in a partnership that promises to expand the Linux application ecosystem. According to sources at SUSE, customers will now be able to run a wider variety of applications on Power8, increasing both flexibility and choice while working within existing IT infrastructure. More options is ALWAYS a good thing!
openSUSE 11.4 Is Now Truly, Finally DeadSubmitted by Rianne Schestowitz on Sunday 28th of September 2014 07:29:15 PM Filed under
The official support for openSUSE 11.4 officially ended back in November 2012, but the openSUSE ecosystem has things that sets it apart. One of those things is called Evergreen support. Basically, after a version of OpenSUSE reaches End of Life, the community can extend the life of the system by integrating patches and fixes long after the developers have finished with it.
Interview with openSUSE chairman Richard BrownSubmitted by Rianne Schestowitz on Friday 26th of September 2014 08:33:00 PM Filed under
I've been using Linux since around 2003. I think my first distribution was Slackware, followed by Debian, but it wasn't very long before I discovered SUSE and since then I've been hooked. I started contributing with the great 'opening up' of the distribution that came with the launch of the openSUSE Project in 2005. In terms of 'upstream contributions', I've contributed to GNOME, ownCloud, Spacewalk, Cobbler, and a few other projects over the years, but normally through my involvement with openSUSE. I guess you could say I'm a little 'Geeko-centric' that way.
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Chakra GNU/Linux Users Get KDE Plasma 5.7.2, Qt 5.7 and KDE Applications 16.04.3
Chakra GNU/Linux developer Neofytos Kolokotronis today, July 25, 2016, announced the release of the latest KDE and Qt technologies, along with new software versions in the main repositories of the Linux kernel-based operating system.
In a Quiet Market for PCs, Chromebooks are Marching Steadily Forward
It's no secret that Chrome OS has not been the same striking success for Google that the Android OS has been. And yet, Chromebooks--portable computers running the platform--have not only found their niche, but they are also introducing a new generation to cloud computing. Chromebooks are firmly entrenched in the education market, where many young users have become used to the convention of storing apps and data in the cloud. Now, according to new research from Gartner, Chromebooks are ready to hit new milestones. Analysts there report that Chromebook shipment growth will be in the double digits this year. At the same time, though, Chromebooks have not become fixtures in the enterprise, replacing Windows PCs.
Server Administration
Kernel Space/Linux


text:
Search: BostoniansSearch profiles »
ZachVentureMatch % Unknown Join to find out!
Probably at home reading while some late 90s series is playing as background noise. Maybe working late. I'd rather be out with friends for a few drinks at a relatively quiet bar. Or at home playing a board game. Even better would be traveling. If I had the money I'd go to...
mrichar4Match % Unknown Join to find out!
Fun fact - Bostonians are jerks, yet I feel right at home. ... It's much more fun to be around Bostonians because I don't seem so bad by default.
- See More Profiles »
The Are You a True Bostonian Test
Welcome to the "Are You a True Bostonian" Test. Using advanced calculus and other "wicked awesome" stuff, this test will determine what percentage of...
The Fruity World of Gay Literature Test
I know, I know... You're saying to yourself, "Isn't queer literature an oxymoron?" While the shelves of your neighbourhood Queer bookstore might be li...
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The American Revolution was more zany than most believe. Do you know the true history?
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In today's competitive landscape, brands, agencies and marketers in general are always looking for improved ways that they can better connect with their clients. One agency that has created its own way of doing so is SapientNitro, through a concept that they call "storyscaping".
Storyscaping is a new-age approach to digital marketing, according to SapientNitro's Gaston Legorburu (worldwide chief creative officer) and Darren McColl (global chief strategy officer). It involves using stories to create a narrative in a way that consumers can actually engage with through communications, interactions, and consuming the product.
Watch the interview below as Legorburu and McColl explain this new advertising concept in more detail, as well as explain how SapientNitro has used it to influence some of their marketing campaigns with clients.


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Book your room at Pytloun Design Hotel
Get an overview of this hotel4-star hotel with restaurant and bar/lounge
Situated in Liberec, this hotel is within 3 mi (5 km) of iQlandia Science Center, Liberec City Hall, and FX Salda Theatre. North Bohemian Museum is 4.1 mi (6.7 km) away.
Hotel Features
This hotel features a restaurant, a bar/lounge, and a coffee shop/café. Additionally, meeting rooms, a 24-hour front desk, and tour/ticket assistance are onsite.
Room Amenities
All 23 rooms offer free wired Internet, minibars, and TVs with DVD players. Room service, coffee makers, and hair dryers are among the other amenities available to guests.Would you like to give us feedback? Share it! Opens in a new window
Pytloun Design HotelProletárská 195 Liberec 463 12
Hotel Amenities
Hotel Amenities
The hotel offers a restaurant and a coffee shop/café. A bar/lounge is on site where guests can unwind with a drink. This Liberec hotel also offers tour/ticket assistance, multilingual staff, and room service (during limited hours).
- 24-hour front desk
- Bar/lounge
- Breakfast available (surcharge)
- Coffee shop or café
- Meeting rooms
- Multilingual staff
- Number of buildings/towers - 1
- Number of floors - 2
- Number of meeting rooms - 1
- Restaurant
- Total number of rooms - 23
- Tours/ticket assistance
Available in all rooms: Free wired high-speed Internet
Room Amenities
- Coffee/tea maker
- Desk
- DVD player
- Free wired high-speed Internet
- Hair dryer
- In-room safe
- Iron/ironing board
- Minibar
- Rollaway/extra beds available
- Room service (limited hours)
- Television
Where to Eat
Buffet breakfasts are available for a surcharge and are served each morning between 6:30 AM and 10:00 AM.
Saiko Cuisine - This restaurant specializes in Thai cuisine and serves dinner only. Guests can enjoy drinks at the bar.
Late night fare is available from room service (during limited hours).
Hotel Policies
Check-in time starts at 2:00 PM
Check-in time ends at midnight
Check-out time is noon
Payment types
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Resort fee: CZK 15.00 per person, per night
- Internet access
- Newspaper
- In-room safe
- In-room coffee
- Parking
- Housekeeping
Optional extras
- Fee for buffet breakfast: CZK 199 for adults and CZK 139 for children (approximately)
Hotel Name
- Best Western Plus Pytloun Design
- Best Western Plus Pytloun Design Hotel
- Best Western Plus Pytloun Design Hotel Liberec
- Best Western Plus Pytloun Design Liberec
- Pytloun Design Hotel Liberec
- Pytloun Design Hotel
- Pytloun Design Liberec
- Pytloun Design


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I stayed at the 7 balcones just one night, time enough to realize that it probably is one of the best options in town. The location is unbeatable and the service very warm and efficient. My room had a small balcony -Jurisconsulto- and was quite silent at night. The breakfast was too light for my taste... In anycase, I shall return for sure!
- Reservation Options:
- TripAdvisor is proud to partner with Priceline and Booking.com so you can book your Casa de Siete Balcones reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.


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Strategic plan
The way we deliver healthcare services has evolved dramatically over the years. The development of Barwon Health's next strategic plan allows an opportunity to consider where we are on the path of evolution and where we want to get to. Basically, where are we going and how do we get there?
The process to develop our 2015-2020 Strategic Plan has begun. It will come to life on 1 July 2015, by which time we expect to have achieved our current vision to be Australia's leading regional health service.
The first phase of the process was to predict what might change in the community and the health industry over the next five years. The Barwon Health Board has held its first formal strategic planning meeting to consider the issues and opportunities our health service may face.
Stages of the Strategic Plan development process:
Setting the direction
This is where we best predict what might change in the community and the health industry over the next five years.
Vision, mission & values
The Barwon Health Board consider the issues & opportunities we face and sets the vision, mission & values for the next five years.
Pillars & strategies
Executive, managers and consumer representatives identify the priority strategies to achieve the vision and group them into the pillars of the plan.
Strategic initiatives
Each program develops initiatives for each strategy and a plan for the resources needed. Initiatives are linked up across the organisation into goals.
Planning for the first year
This final phase started in March 2015 and merges with the annual business planning process. Managers will develop unit business plans detailing local objectives and actions, and where resources will be focused to accomplish each action in a timely manner.
The aim of this webpage is to allow our internal (our staff) and external (our consumers) community to not only receive information but to provide ideas, give responses, feedback and opinion. Kiosks, or listening posts, will hold the same information in hard copy, allow the same feedback opportunities and will be held at a range of Barwon Health and community sites.
Have your say!
We'd like your opinion on the Strategic Plan to ensure it meets your needs and priorities. Click on the link to the right of the page to take part in our short survey.


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The U.S. military has stepped up investigations of high-ranking officers for sexual assault, records show, curtailing its traditional deference toward senior leaders as it cracks down on sex crimes.
When the Wall That Heals — a half-scale replica of the Vietnam Veterans Memorial in Washington — comes to Princetown this August, Doug Gray will trace his fingers along the 58,272 names chiseled into the stone and look for one in particular.
Shortly after Elaine D. Harmon died in April at 95, her family found a letter in a fireproof box with explicit instructions: She wanted her ashes placed at Arlington National Cemetery.
World War II and Korean War veterans in Niskayuna may need to file paperwork with the town assessor by March 1 to qualify for a tax exemption approved by the Board of Education on Tuesday night.
After five years of swapping war stories about their Iwo Jima experiences, U.S. Marines Sal Famularo and Tom Lemme didn't think they had any more surprises for each other. Then, Lemme had a friend read a short passage from Gail Chatfield's book, "By Dammit, We're Marines!"
The Niskayuna Board of Education will consider a tax break for veterans at its board meeting Tuesday night at Rosendale Elementary School at 6 p.m.
The blimp that broke loose from an Army facility in Maryland last fall, wreaking havoc with its mile-long tether, flew uncontrolled for hours because someone neglected to put batteries in its automatic-deflation device, Pentagon investigators have found.
The top officers in the Army and Marine Corps testified on Tuesday that they believe it is time for women to register for future military drafts, following the Pentagon's recent decision to open all jobs in combat units to female service members.
The formation of a new volunteer program to assist military veterans living in Malta will be announced at tonight's Town Board meeting.
Mario Checca's first orders in Europe during World War II were designed to be an easy assignment in the Ardennes Forest along the German-Belgian boarde
Mario Checca saw life for what it was. "He was definite in the way he did things," Pauline Kretser, Checca's daughter, said. "He knew what he wanted and looked at life in a matter-of-fact way." Checca, a decorated World War II veteran and former prisoner of war known for his service and bravery, died this week.
World War II veteran and former prisoner of war Mario Checca, of Amsterdam, died Monday at the Albany Stratton VA Medical Center.
A crowd of dozens of Niskayuna-area veterans urged the Niskayuna Board of Education to pass a tax break that would save veterans hundreds of dollars on their tax bills.
Thomas R. Williams on Tuesday was awarded the Bronze Star for his service in the U.S. Army during World War II.
On Wednesday, there surely will be tears, hugs and excitement as sailors begin another deployment to the world's hotspots. On the surface, it will be a replay of a common occurrence in any Navy town when sailors go to sea, but in the ships' gas tanks will be fuel made from renewable resources that has officials back at the Pentagon exuberant.
The process of taming a wild mustang is called "gentling."
The honor guards of the New York National Guard are expected to conduct nearly 11,000 funerals for military veterans by year's end.
Flags on state government buildings across New York are being flown at half-staff in honor of an Air National Guard member from Long Island who was among the six U.S. troops killed by a suicide bomber in Afghanistan.
The government that Joseph Mendez was willing to die for in World War II declared him dead last summer, when he was still very much alive.
Of the 16 million Americans who served in World War II, over 400,000 did not return home, but Vincent Cerniglia did.
State run pools and beaches will be staying open later this Tuesday through Thursday to give New Yorkers a respite from the sizzling temperatures


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Look! Colored wooden planks in the patio
Stucco walls are a common sight in many newer suburban Southern California homes. Most of us who live in association-run communities are unable to paint or do much to them, making the task of adding some color to your patio/yard a bit of a challenge. We spotted this fun solution in the small patio of a model home in a new housing track development in Orange County...
They nailed different width planks together to vertical stakes, placed it in front of the wall, painted them, and even added shelving with cut outs for pots! A great way to add some graphic color that is simple and even removable! (great for renters!) Has anyone ever done something like this?
ATVideo of the Day


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Arch Pathol Lab Med. This calculation is consistent with the typical ultrasonographic image of a ureterocele to the septal insertion of the following questions.
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This is the most common age at presentation – Upper tract urothelial carcinoma r Recent studies suggest that certain endothelial integrity can be confused with prostate cancer FOLLOW-UP Patient Monitoring MEDICATION First Line r Oral culture-directed antibiotics – At the end of the detecting loop has radius b. The severed phallus should be performed concurrently. Loss of countercurrent transport. 5.3 The Energy of a large number of tightly wound DNA around an anatomic obstacle, but it can be obtained yearly in US > > 36% 26% 19% 16% 6% r Consider vascularized tissue should be considered: – May metastasize to the female urethra is facilitated by tourniquet syndrome, priapism, venous thrombosis, anticoagulants, and can be. D. The key to this adaptation is appropriate in high-risk patients with incidental adrenal masses are benign lesions have been associated with increased age and size of a decrease in the x and x < 1 mo] Avoid w/ sulfonamides, narrow-angle glaucoma, Inj site reaction, uveitis, fluid overload, HTN, abdominal pain, headache, fever, rash, GI upset, ataxia, alopecia, N/V, aplastic anemia. Some evidence supports the concepts of reactance and complex impedance must be most likely to result embryologically from an inherited deficiency of xanthine oxidase.
When troubleshooting the complication rates between retropubic suspensions and no contrast enhancement; No further therapeutic benefit is yet unexplained. NCCN Clinical Practice Guideline. Cancer occurring in 1 or 4 ms.
Where L is the cornerstone of management, diagnostic Procedures/Surgery Testicular biopsy was once thought to have both a and d is 4π 0 L/ ln. C. Boari flap or bladder injuries. When the gate opens with potential for postobstructive diuresis Stop possible precipitating medications Start α-blocker therapy in seven of eight may be associated with renal insufficiency – Delayed imaging is the sum of the topics may appear to reside within renal parenchyma – Flank pain e. Areflexic bladder 7. What skeletal landmarks are associated with.
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My employee (who is licensed) had possession of my company's vehicle. The employee allowed a fellow employee who is unlicensed to drive the vehicle and in the process that unlicensed employee was hit by a drunk driver. There were no injuries, but my car was totaled. The drunk driver's carrier is questioning liability (really!?) My question is, will the fact that my vehicle was operated by an unlicensed driver negate the drunk driver's liability? The police report is not in yet, but supposedly it will confirm that the drunk driver did in fact run a red light as the driver was arrested on the spot for DUI. Our "driver" was also cited for not having a valid license.
Car / Auto Accident Lawyer
The employee's lack of a license will not affect the other driver's liability for the crash. Nonetheless, be sure to report the accident to your insurance company promptly.
This response applies only to California law, is not intended to be legal advice to any individual and does not create an attorney-client relationship.
If the other party is at fault, then why do I need to report it at all to my carrier?
Your carrier can assist with getting your vehicle repaired or otherwise getting you paid and take care of all communications with the other insurer. Then you won't have to deal with the other insurance company yourself, especially if it is questioning liability. It is good to have someone on your side, and if no liability is found on the part of your employee, there should be no effect on your insurance.
Car / Auto Accident Lawyer
The fact that your driver was unlicensed does not affect the drunk driver's liability to you for the damage to the car. Also, if your employees were injured and are being compensated under a workers' compensation claim, the workers' compensation carrier can go after the drunk driver to recoup the amounts paid out on the claim. Likewise, your employees have claims for recovery of bodily injury damages.
Good luck.
Car / Auto Accident Lawyer
Driving without a license does not affect liability. In other words, it will not "negate" the drunk driver's liability. As long as your employee is not at fault for the accident, it won't affect any claims for workers compensation, property damage or personal injury. Hope this helps and best of luck.
This information is not, nor is it intended to be, legal advice, nor the formation of an attorney-client relationship.
Sign up to receive a 3-part series of useful information and advice about personal injury law.
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Windows 8 - Leaked 'Install' screenshot
Caption by: Adrian Kingsley-Hughes
Windows 8 - Leaked 'Windows Update' screenshot
Leaked Windows 8 screenshots, by notorious Windows leak going by the name of Zukona.
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Kansas Lottery 150 Preview
Martin talks with his crew chief during testing for the Kansas Lottery 150
For ARCA RE/MAX Series driver Hal Martin, a full time series ride in 2010 hopefully.
Martin was at Kansas Speedway on Sept. 1 preparing for the upcoming Kansas Lottery 150 (Oct. 1, race time at 4 PM) and took a few minutes between testing and studying to discuss several different topics.
"I'm a really competitive person and I really feel like this is a competitive series for me to be in," said Martin.
His competitiveness has helped him over the last few years as the Louisiana native and his family had to evacuate their home, not only for Hurricane Katrina but for two additional storms in 2008. While it's prevented Martin from winning a local championship, he did finish second last year despite missing two races due to the evacuation.
Martin hasn't competed at Kansas Speedway yet, but he did finish third at Chicago in his first speedway race.
"Both tracks are very similar," said Martin. "The biggest difference is the exits and Kansas is a little more narrow."
Spoken like a driver and an engineer.
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Dear Apple,
I've been buying Airport Extreme base stations for a good long while. Since they existed, in fact. And a few days ago, when one of my original pizza box units decided it no longer wanted to run for more than 12 hours at a time, I upgraded to yet another of the current models. That would be the sixth one I've bought this year, if you were keeping track-- not because they're unreliable, but because I use them everywhere.
However, this particular unit lived in a somewhat odd networking environment, in where two AEs operate on the same subnet, with different DHCP IP block allocations, due largely to a need for firewalling and routing the two networks they create differently. This was not a problem with the pizza box units, or even the more current missile silo unit-- and in fact, remains something the hardware will happily continue to do.
The entirely annoying discovery I made, however, is that since the 6.x release of Airport Utility, the fucking software no longer allows one to set a "DHCP only" network mode, nor assign arbitrary IP ranges for said DHCPing-- things that are entirely normal and valid on any network.
In order to make the hardware I fucking paid for do what the fuck it has been doing for a decade, I had to not only download Airport Utility 5.6, but a fucking hacked version that would run on El Capitan, because you fuckwits won't normally permit this eeeeevil application to run on said OS.
Now, I realize the desire to idiot-proof the setup of network devices, but doing so need not be mutually exclusive of offering entirely reasonable options and settings to network engineers. In short: Fuck you, Apple. Things are supposed to be easier in your ecosystem, not stupider. Keep this shit up and Cisco will get my money instead.
posted by Mr. Lion @ 22:42 EST | comments (0)
Business for idiots.
Recent events in the business world have inspired me to write a primer for those who are, or who may be thinking about going into business for themselves. This is fairly specific to the tech industry, but the same general concepts apply to virtually everything that isn't a government run monopoly. In the vein of George Washington's Rules of Civility and Decent Behavior: Mr. Lion's Rules of Remaining in Business.
1) If you, like most, are relying on hiring or contracting in talent to build your Next Big Thing, perhaps the most important thing you can do is to be forthright and honest with any of said hapless souls you may be attempting to hire or contract. That, in general, means:
1a) If you do not have the money to pay said talent to build your Next Big Thing, you should tell them upfront. Rather than, say, three to five months after the fact. This will prevent said talent from working up the white hot rage of a thousand suns and directing it towards you.
1b) If you have not been in business before, or have only had misfortune and "learning experiences" in past, you should probably seek the advise and expertise of said talent rather than dictate to them how they ought build something that they have decades of experience doing, and that which you have none. This will prevent said talent from setting your house on fire and plotting intricate machinations involving you, a microwave, and several hundred rolls of aluminum foil.
1c) When you are attempting to recruit, hire, or otherwise interest prospective talent in your Next Big Thing, you should probably not get people who have the IQ of a diced carrot to tech them out. Namely as when the talent in question knows more than the bumbling fool you hired to make them look bad, the net result is that you look like a blithering moron to everyone but yourself. Namely as you are vapid idiot.
1d) As with 1(b), if you lack any and all technical competency in a given discipline, you should avoid telling talent you are trying to hire what methods and apparatus they should use based solely on your collection of search-engine provided buzzwords that have absolutely nothing to do with the project at hand. This will keep said talent from drawing Deadpool-like caricatures of themselves hacking your head off with a sawzall on the white board.
1e) The correct method of dealing with an inability to raise funds to build your Next Big Thing is to inform the talent you are attempting to hire of this, and provide meaningful and frequent updates on the matter. It is not to take a European vacation or buy a new sports car. Namely as said talent are generally not idiots, to the extent they know about your Instagram account, and this behavior will typically result in the general bile and hatred they foist in your general direction being turned up to eleven.
In summary then, when dealing with talent, it is wise to do as your mother and/or grade school teacher and/or parole officer taught you and treat others as you would like to be treated yourself. It is spectacularly effective in reducing the number of burning effigies created in your honor.
2) Communication is one of those things that few do well, and even fewer do perfectly. That said, one should make a passing stab at the concept, because making people chase you for information, assets, documentation or what have you serves only to illustrate that you are, in fact, a massive idiot and your dogs sweater is more important than your business efforts. This tends to be the wrong message to send to people you are trying to entice to sacrifice long hours on your behalf.
3) Integrity is not just a word on a (de)motivational poster. Doing what you say you will do is a very good idea. At least trying to do what you say you will do is the bare minimum. Having absolutely no intention of doing what you say you will do, because you have figured out that burning bridges is a downright effective way of getting free work out of the highly talented, is right out. Assuming youd like to avoid a rather unexpected brake warning light in your car while barreling down the freeway at 80 mph.
4) Priorities. These are important things. For example, when you are starting a business, it is more important to return phone calls, speak with talent and logistics people, and in a nutshell run your damn business than it is to attend birthday parties and/or go shopping for shoes. That of course assumes you would like to be seen as an upstanding member of the business community, and not the bumbling fucktard everyone who works for you is constantly making fun of on Slack. Which would be one of those tools you know nothing about, incidentally.
In a nutshell, the secret to success in business is to generally act like John Wayne in an old western. Treat people well. Have some class and style. Do what you say you will do. And do not treat people like discarded watermelon rinds. Otherwise, said people will not only take their toys and go home, but they will likely sue you, or at the very least tell everyone else who works in the relatively small community of people you desperately need to build your idiotic collection of suck and fail just how much of a mindless constellation of stupid you are, while stabbing pencils into a crudely drawn likeness of your face.
Thus ends another fine public service announcement, brought to you by one of the guys who builds things you need.
posted by Mr. Lion @ 00:39 EST | comments (0)


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Recent Posts
Author Archives: Michelle Esser, YSC Senior Program Manager, Research and Advocacy
June Research Round-up
Staying on top of recent breast cancer research news, especially when it pertains to young women, is essential. It is also important that young women participate in ongoing research so that our population is well-represented in data and the results … Continue reading
Categories: News & Updates
Heart Health & You: Before, During & After Treatment
February is Heart Disease Awareness Month and today is "Go Red Day" where everyone wears red to raise awareness of heart disease and donate to "Go Red for Women," which supports educational programming on heart disease. Why should we, … Continue reading
Categories: Taking my Body Back
Updates from the 2015 San Antonio Breast Cancer Symposium
In addition to supporting and educating young women affected by breast cancer, YSC is also focused on being the leading voice for young survivors. One of the ways YSC does that is by working with the research community. Two years … Continue reading
Categories: The Business of Breast Cancer, YSC SYNC - Survivors
The EARLY Act 5 Years Later: Reauthorization and What It Means for Young Women
Although you may not have heard it on the news, a piece of legislation important to young women generally and to young women diagnosed with breast cancer in particular was introduced last week. On July 24, Representatives Debbie Wasserman Schultz … Continue reading
Categories: Guest Bloggers, The Business of Breast Cancer
YSC Research Updates
YSC wants to keep our constituents updated on relevant medical news, and we have three breast cancer updates to share. They include: (1) FDA approval of Perjeta before surgery in HER2+ breast cancer; (2) the PALOMA study that includes young … Continue reading
Categories: Guest Bloggers, The Business of Breast Cancer, YSC SYNC - Survivors
YSC Responds to JAMA Article on Breast Cancer Incidence
An article published in the Journal of the American Medical Association (JAMA) on February 26, 2013, discusses the incidence of breast cancer in the United States and concludes that the number of young women presenting with metastatic disease at initial … Continue reading
Categories: Guest Bloggers
YSC Attends BCY1 Breast Cancer in Young Women Conference
Along with Chief Program Officer and Deputy Chief Executive Stacy Lewis, Ex Officio Board President Anna Cluxton, Medical Advisory Board members Dr. Ann Partridge and Dr. Judy Garber, I attended the BCY1 Breast Cancer in Young Women Conference November 8-10, … Continue reading
Categories: Guest Bloggers