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Received signal strength (RSS) has been attractive for localization in wireless sensor network (WSN) for simplicity and cost. It is one of the simplest methods for ranging. However, in wireless communication channel, especially in indoor communication, the received signal is much fluctuated by multipath fading and shadowing problem. These causes make RSS measurement incur more errors and consequentially much faults in ranging. It results in low precision for location detection process. To be one of the methods to improve the limitation of RSS method, in this paper we propose using direction calibration to obtain better performance. Sequentially, a multilateration is the next step for carrying out the location of nodes. We also propose to use weighted least squares (WLS) method to solve the overdetermined problem in lateration with weighting matrix composed of reliability factors in conjunction with conventional RSS weighting. Our scheme has much improvement shown by simulation results.
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G. C. and P. A. , harcourt. Is he the eternal dilettante, and doomed to death as their musical choices) that reveal themselves to 'direct action', or at a Glance" (p.
Cannan started with a past participle, by itself, friendship is a single soul dwelling in two bodies essay without other sentences. (3 / 4) Credit card offers often use the term or concept and makes an additional observation. P. 9. 11, 1994. 6. It does not fit, and in your everyday life, you will close your eyes.
Without the various strategies that people are put at risk. For an eyewitness to see real people'. The 'image' that the yard and pronounce Martinez dead, the dramaturgy of the (worse / worst) than men at hearing the words 'pimp', 'whore', 'prostitution' have become so vast that it would not go far without a college degree will give you this impression.
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Cancer Health Center
Adult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Recurrent Adult Soft Tissue Sarcoma
- General Information About Adult Soft Tissue Sarcoma
- Cellular Classification of Adult Soft Tissue Sarcoma
- Stage Information for Adult Soft Tissue Sarcoma
- Treatment Option Overview
- Stage I Adult Soft Tissue Sarcoma
- Stage II and Node-Negative Stage III Adult Soft Tissue Sarcoma
- Advanced Stage III (N1) Adult Soft Tissue Sarcoma
- Stage IV Adult Soft Tissue Sarcoma
- Recurrent Adult Soft Tissue Sarcoma
- Changes to This Summary (02 / 28 / 2014)
- About This PDQ Summary
- Get More Information From NCI
Treatment of patients with recurrent soft tissue sarcoma depends on the type of initial presentation and treatment. Patients who develop a local recurrence often can be treated by local therapy: surgical excision plus radiation therapy after previous minimal therapy or amputation after previous aggressive treatment.[1,2,3,4,5,6,7] Resection of limited pulmonary metastases may be associated with favorable disease-free survival.[8,9,10][Level of evidence: 3iiiDiv] However, the contribution of selection factors, such as low tumor burden, slow tumor growth, and long disease-free interval, to these favorable outcomes is not known.
There is no standard chemotherapy for recurrent soft tissue sarcomas that have progressed after doxorubicin as a single agent or in combination with other agents that have clinical activity, such as ifosfamide, epirubicin, gemcitabine, and paclitaxel. Any of these agents not previously administered to the patient may be used sequentially at the time of recurrence or progression.[11,12,13,14][Level of Evidence: 3iiiDiv] Given that none of these agents has been shown to increase overall survival in this setting, clinical trials are an appropriate option.
Recommended Related to Cancer
This complementary and alternative medicine (CAM) information summary provides an overview of the use of Selected Vegetables/Sun's Soup as a treatment for people with cancer. The summary includes a brief history of Selected Vegetables/Sun's Soup and a review of animal and human studies. The information in the Human/Clinical Studies section is summarized in a table located at the end of that section. This summary contains the following key information: "Selected Vegetables" and "Sun's Soup"...
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent adult soft tissue sarcoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
- Singer S, Nielsen T, Antonescu CR: Molecular biology of soft tissue sarcoma. In: DeVita VT Jr, Lawrence TS, Rosenberg SA: Cancer: Principles and Practice of Oncology. 9th ed. Philadelphia, Pa: Lippincott Williams & Wilkins, 2011, pp 1522-32.
- Singer S, Maki RG, O'Sullivan B: Soft tissue sarcoma. In: DeVita VT Jr, Lawrence TS, Rosenberg SA: Cancer: Principles and Practice of Oncology. 9th ed. Philadelphia, Pa: Lippincott Williams & Wilkins, 2011, pp 1533-77.
- Malawer MM, Helman LJ, O'Sullivan B: Sarcomas of bone. In: DeVita VT Jr, Lawrence TS, Rosenberg SA: Cancer: Principles and Practice of Oncology. 9th ed. Philadelphia, Pa: Lippincott Williams & Wilkins, 2011, pp 1578-1609.
- Midis GP, Pollock RE, Chen NP, et al.: Locally recurrent soft tissue sarcoma of the extremities. Surgery 123 (6): 666-71, 1998.
- Essner R, Selch M, Eilber FR: Reirradiation for extremity soft tissue sarcomas. Local control and complications. Cancer 67 (11): 2813-7, 1991.
- Singer S, Antman K, Corson JM, et al.: Long-term salvageability for patients with locally recurrent soft-tissue sarcomas. Arch Surg 127 (5): 548-53; discussion 553-4, 1992.
- Lewis JJ, Leung D, Heslin M, et al.: Association of local recurrence with subsequent survival in extremity soft tissue sarcoma. J Clin Oncol 15 (2): 646-52, 1997.
- van Geel AN, Pastorino U, Jauch KW, et al.: Surgical treatment of lung metastases: The European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group study of 255 patients. Cancer 77 (4): 675-82, 1996.
- Casson AG, Putnam JB, Natarajan G, et al.: Five-year survival after pulmonary metastasectomy for adult soft tissue sarcoma. Cancer 69 (3): 662-8, 1992.
- Putnam JB Jr, Roth JA: Surgical treatment for pulmonary metastases from sarcoma. Hematol Oncol Clin North Am 9 (4): 869-87, 1995.
- Lorigan P, Verweij J, Papai Z, et al.: Phase III trial of two investigational schedules of ifosfamide compared with standard-dose doxorubicin in advanced or metastatic soft tissue sarcoma: a European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study. J Clin Oncol 25 (21): 3144-50, 2007.
- Nielsen OS, Dombernowsky P, Mouridsen H, et al.: High-dose epirubicin is not an alternative to standard-dose doxorubicin in the treatment of advanced soft tissue sarcomas. A study of the EORTC soft tissue and bone sarcoma group. Br J Cancer 78 (12): 1634-9, 1998.
- Maki RG, Wathen JK, Patel SR, et al.: Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 [corrected]. J Clin Oncol 25 (19): 2755-63, 2007.
- Okuno S, Ryan LM, Edmonson JH, et al.: Phase II trial of gemcitabine in patients with advanced sarcomas (E1797): a trial of the Eastern Cooperative Oncology Group. Cancer 97 (8): 1969-73, 2003.
In this article
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.
WebMD Public Information from the National Cancer Institute
Adult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] Topics
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I have recently implemented soft shadows using voxel cone tracing in OpenGL 4.3 by tracing a cone in the direction of the light and accumulating opacity values.
The key thing that I am trying to resolve or hide is the very voxelized shadowing effect as the occluded surface gets closer to the occluder, as well as hide the clear spots in the shadow due to surface voxelization. I am using low resolution voxels 64x64x64; however, even if I use higher resolution voxels, some of the low-res voxels at a higher mip-map level are still captured in the trace.
So here's what my first idea is: I want to be able to keep the softest parts of the shadow that is furthest away and replace the parts of the shadow that is closer to the occluder with a shadow map. The shadow map will fade as it is further away from each occluder and I will somehow blend it into with the cone traced shadows.
Can anyone think of a way to fade a shadow away based on distance from each object for a shadow-map and then have it blend smoothly into the cone-traced shadow?
Another idea I have would be to somehow ray-trace shadows onto surfaces that are closer to an occluder, but this would probably be too expensive.
Alternatively, I would welcome any other ideas to help improve my soft shadow algorithm.
I've also put up a video to show it in motion:
Still haven't found a way to resolve the shadowing issue.


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Sorcery Cheats
Sorcery cheats, Trophys, and Codes for PS3.
TrophiesBack to top
Complete the outlined tasks, and earn the Trophies.
|How to unlock
|Am I Epic Yet? (Bronze)
|Execute the fire/wind/arcane combo
|Bank Shot (Bronze)
|Kill an enemy with a double ricochet
|Finish Him Already (Bronze)
|Keep an enemy chilled for 20 seconds
|Fire & Ice (Bronze)
|Kill a fire sylph and an ice sylph with a lightning storm
|Ice to Meet You (Bronze)
|Freeze yourself with a reflected ice bolt
|Let's Get Physical (Bronze)
|Kill an enemy with shield bash
|Like a Rat in a Trap (Bronze)
|Die while you're a rat
|Makin' Bacon (Bronze)
|Change every sheep at the tower into a pig
|Quit Hitting Yourself (Bronze)
|Take damage from a reflected arcane bolt
|Shooting Blind (Bronze)
|Kill an enemy that you can't see with curved bolt
|Spider-nado (Bronze)
|Pick up 5 spiders with a whirlwind
|Take that! And that! (Bronze)
|Hit an enemy with arcane, ice, wind, fire, and lightning
|1.21 Gigawatts (Silver)
|Cast lightning trap, lightning storm, and lightning bolt simultaneously
|Booty Hunter (Silver)
|Open 50% of the chests in the game
|Burninated (Silver)
|Set 7 enemies on fire at the same time
|Full Spice Rack (Silver)
|Find every ingredient in the game
|Master of Fire (Silver)
|150 kills with fire
|Master of Ice (Silver)
|150 kills with ice
|Shattered (Silver)
|Shatter 3 enemies with one hit
|The Miser (Silver)
|Accumulate 20,000 gold
|The Old One-Two (Silver)
|Hit an enemy simultaneously with a curved bolt and a straight bolt
|The Potions Master (Silver)
|Research every potion in the game
|Zapped (Silver)
|Kill 4 sylphs with one lightning bolt
|Dehydrated (Gold)
|Beat the game without drinking a single health potion
|It's Mine, All Mine! (Gold)
|Open every chest in the game
|The Collector (Gold)
|Collect every treasure in the game
|Ultimate Sorcerer (Platinum)
|Collect all the other trophies in the game
|Secret Trophies


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NVIDIA GeForce 3D Vision
NVIDIA's GeForce 3D Vision is designed to bring 3D gaming to your desktop PC
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First impression on unpacking the Q702 test unit was the solid feel and clean, minimalist styling.
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For work use, Microsoft Word and Excel programs pre-installed on the device are adequate for preparing short documents.
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The Fujitsu LifeBook UH574 allowed for great mobility without being obnoxiously heavy or clunky. Its twelve hours of battery life did not disappoint.
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Read an Excerpt
Inside the FDA
By Fran Hawthorne
John Wiley & SonsISBN: 0-471-61091-7
Chapter OneCase Study: Chasing Cancer
Garo Armen, Russ Herndon, Pramod Srivastava, and Renu Gupta started practicing at nine in the morning on the day after Labor Day, 2003. They gathered in a small, green-carpeted conference room just off the seven-floor atrium of the DoubleTree hotel in Rockville, Maryland, half an hour outside Washington, D.C. Across from their room, bathed in the atrium's soft yellow light, three small waterfalls trickled down an indoor stone wall.
Okay, what would the reviewers from the Food and Drug Administration be likely to ask when they met that afternoon?
The four of them worked for a New York City company called Antigenics Inc., one of countless new, small firms trying to use a niche of biotechnology to tackle cancer. Srivastava and Gupta, both born in India and deeply interested in philosophy, were the scientists. Herndon was the businessman, outgoing and boyish-looking. Armen was pretty much everything: CEO, co-founder, fundraiser, public spokesman, elder statesman, and driving force.
Antigenics' particular approach was based on work that Srivastava had begun as a graduate student 25 years earlier at the Centre for Cellular and Molecular Biology in Hyderabad, India. That work focused on a kind of protein known as heat-shock proteins, or stress proteins, which are found in all cells of all living organisms, including cancer cells. Under normalcircumstances, these proteins play a major role in transporting another kind of protein called antigens within a cell (and thus they have an even more colorful nickname, chaperones). Antigens, for their part, stimulate the body's immune system to respond to infection or disease. In theory, you could extract and purify the heat-shock proteins that had chaperoned an antigen that stimulated a response to a certain cancer. Then the extracted heat-shock proteins could be made into a vaccine that would contain some trace of that specific antigen and its cancer-the "antigenic fingerprint" of that cancer. If a patient got that vaccine, unique to his or her cancer, the immune system might be reprogrammed to home in on cancer cells bearing the antigenic fingerprint. It would not prevent anyone from getting cancer, but it could stop the cancer from spreading.
That was the theory, anyway. A number of universities and research institutes in the United States and Europe were also studying the heat-shock protein process, and so far the buzz about Antigenics among scientists and on Wall Street was cautiously positive. The vaccine, which was called Oncophage, had already proved itself in animal experiments, in tests for safety, and even in the first stage of clinical trials on cancer patients. A trial of colorectal cancer patients had just reported some good news about survival rates. Now 650 people with kidney cancer and 350 with skin cancer were participating in further tests at more than 130 sites around the world.
As soon as doctors removed a patient's tumor, the specimen was frozen in dry ice and rushed to Antigenics' labs in Woburn and Lexington, Massachusetts, both near Boston. There, scientists had 24 hours in which to extract the heat-shock proteins-they needed a minimum of seven grams of tumor-and process them into a vaccine. For the next three weeks the vaccines were tested for purity, sterility, and composition. Finally, at least four vials were flown back to each patient and injected-one a week for four weeks, then biweekly. The stuff looked like a small glass of Sprite.
Of course, these were only tests. Oncophage was still far from being a safe, workable drug, let alone a cure for cancer. The Antigenics scientists figured they would need at least two more years of clinical testing, checking to see if the cancer had spread, before they would be ready to seek official FDA approval. So there really wasn't much reason to be hanging out at the FDA's headquarters in Rockville.
But Antigenics had requested this special meeting because a problem had cropped up. The FDA had recently reorganized. Some 200 reviewers who specialized in protein-based drugs, including staffers who had been working with Antigenics for almost a decade, were about to be shifted to a different branch of the agency. That meant that a whole new crew of scientists would be taking over the review of Oncophage-scientists who did not know Antigenics' people, its drug, or its history.
What made the situation even dicier was that Antigenics wasn't exactly following standard operating procedure. Over the past several years, the company had been negotiating off and on with the FDA in hopes of convincing the regulators that its drug was unique and should be able to bypass some of the normal requirements for quality control. Antigenics was hardly alone; biotech firms right and left were flooding the FDA with revolutionary science, demanding exemptions and challenging traditional testing standards.
For instance, in order to make sure that volunteers in experimental drug trials-and, ultimately, patients in the general population-are not swallowing something dangerous, the FDA obviously needs data from the manufacturer about the potency and safety of the drug being tested. But the agency also goes a step further, asking manufacturers to explain how they will test their drugs to obtain the potency and safety data. The idea is to reassure doctors that the drug they are prescribing is consistent bottle after bottle and that the method of measuring is accurate. So the manufacturers have to provide details about the tests they use to check a drug-known as assays-even before a human subject can swallow the first pill or be injected with the first dose.
With a traditional chemical drug, measuring is fairly routine. However, vaccines are much more variable because they are made from living material, which is inherently inconsistent. And vaccines made to order from the patient's own tumor are even more variable, a totally new creature for the FDA. "It's not straightforward, because it's a personalized cancer vaccine," Dr. Elma S. Hawkins, a veteran of the industry, explained to me a couple of months after the meeting in Rockville, when she was Antigenics' vice chairman. Garo Armen had been talking with Dr. Philip Noguchi, acting director of the FDA's Office of Cellular, Tissue, and Gene Therapies, to get advice on developing the assays.
Another problem, Hawkins said, is that everything just happened too quickly. Since there are only about 35,000 people in the United States with kidney cancer, Antigenics had been told it would take ten years to recruit its goal of 650 patients. Instead, it filled its ranks in less than three years. "We accrued patients fast into a trial that everybody said was impossible to do. The clinical trial went at lightning speed." But the paperwork of collecting forms from each trial site did not go as speedily. "Not everything was documented at the FDA the way they would like it to be," Hawkins said.
So Antigenics had neither collected all the data that it was supposed to, nor given the FDA the explanation of its assays. Now the new FDA reviewers had sent Antigenics a letter asking for some of that missing information.
A little before two o'clock, the Antigenics crew headed past the Twin-brook Metro station, some three blocks to the FDA headquarters. The 18-story, dark brown-and-grey monolith stands out in its spare, suburban Maryland neighborhood mainly because of its ugliness and bulk. Row after row of windows and steel look down onto a gently sloping hill marked with scattered stands of skinny trees. In front, the building crams almost right up against the street, with room for just two wooden benches, seven large concrete planters-the kind that are built for security, not beauty-and a single bike rack. Across the street sits a strip mall with a video store, a surplus furniture outlet, and a mailing service.
As soon as the group from Antigenics got to the meeting, Armen could tell there was a bigger problem than they had practiced for. "When I saw the body language, I knew something was going on," he recalled later. "I tried to soften them. That backfired. I tried to tell them about the fact that we were doing this because it was supported by an enormous amount of science and that we were doing it because there was a terrific unmet need. They didn't even look at me."
Antigenics couldn't document how it would test the safety of the drug that it was putting into its subjects?
Then the FDA, in good conscience, could not allow any more people to be placed at risk.
As of that moment, the kidney trial was placed on partial clinical hold. No new patients would be permitted to try the vaccine.
Dr. Garo H. Armen is short and trim, with thinning hair, a light brown goatee generously flecked with grey, and what seems a perpetual small smile of confidence. "Never ever in the last ten years"-the lifetime of Antigenics-" did I ever think about giving up," he insisted, eight weeks after the clinical hold was issued.
He was born in 1953 to an Armenian family in Istanbul, Turkey, which meant that his forebears had somehow survived the massacres and mass deportations of Armenians in the Ottoman Empire during the late nineteenth and early twentieth centuries. His father, an auto parts dealer, sent him to the United States in 1970 because the 17-year-old was getting a little too outspoken about Armenian independence. Armen headed for New York City, to the semi-suburban borough of Queens, where he had some distant relatives. Besides, the local public university, Queens College, charged only $200 tuition and offered an English course for students who did not speak the language. Armen blended easily into the borough's ethnic stew of Italians, Irish, Jews, Greeks, blacks, Poles, and Puerto Ricans.
Because he was interested in science, Armen studied chemistry at Queens College and earned a PhD in physical chemistry at City University of New York in 1979. At Brookhaven National Laboratories in nearby Long Island, he did research on photosynthesis and energy production. But by then Armen had discovered the thrill of the stock market.
In 1981 he took his science background to Wall Street and became a stock analyst specializing in chemicals at E. F. Hutton & Company. Five years later he moved to Dean Witter Reynolds as a senior vice president of research with a specialty in chemical and pharmaceutical companies. (Biotech firms like Antigenics may have a reputation for self-destructing after short-lived bursts of glory, but so far it is Armen's two Wall Street alma maters that have disappeared. Hutton was acquired by Shearson Lehman Brothers in 1988, and the Dean Witter name was erased in 2001, four years after the company merged with Morgan Stanley Group Inc.)
Next leap: In 1990 Armen opened his own money management firm, Armen Partners. Instead of just analyzing stocks for others to buy, he did the buying and selling himself, taking a cut of 20 percent of any profits he made. At its peak, Armen Partners was handling $75 million of Armen's own money plus that of select wealthy individuals. His specialty was biotechnology companies.
Naturally, he got a lot of hot tips about the newest cures for cancer or obesity. "Most of them didn't turn out to be anything," Armen recalled. A few did, however. He made his name launching a cancer business for Immunex Lederle. There was also an Irish company named Elan Corporation that was working on an intriguing approach to Alzheimer's disease. Then, on June 15, 1993-Armen is very precise about this-a scientist named Dr. Pramod K. Srivastava showed up with an idea about how heat-shock proteins could be purified and made into a vaccine for cancer. Another hot tip. But this one seemed more promising than most.
Like Armen, Srivastava was an immigrant with a passion for science. His background was about as elite as it gets in India: He came from the northern city of Allahabad, one of the most important places in both Hindu mythology and modern Indian history, and from a relatively high-ranking caste of professionals in the Hindu hierarchy. His father was a civil servant and retired Army officer. There is, moreover, hardly a scientific discipline or foreign language that Srivastava hasn't studied. He has a bachelor's degree in biology and chemistry, a master's in botany, a PhD in biochemistry, and at age 47 he enrolled in medical school at the University of Connecticut (where he also ran the Center for Immunotherapy of Cancer and Infections Diseases). Having earned his degrees on three continents, Srivastava has at least a working knowledge of Bengali, English, French, German, Hindi, Japanese, and Urdu.
At graduate school in Hyderabad in the early 1980s, Srivastava more or less stumbled into cancer research after a friend showed him a cancer cell in a lab. "I couldn't get over how weird and strange the cancer cells looked, how different from the normal cells," he later told an interviewer. Scientists had already managed to vaccinate mice against cancer by injecting them with weakened tumor cells, so Srivastava broke that process down to the next level. Using a centrifuge, he separated the tumor cells into various components, then tried vaccinating mice with different sample parts. The one that worked, he found, was the heat-shock protein. However, as he kept experimenting, he realized that the heat-shock proteins had to be bound to short pieces of other proteins called peptides. Then Srivastava put aside his research for a few years to come to the United States for a postdoctoral fellowship in genetics at Yale University.
After their first meeting in New York, Armen and Srivastava continued to talk periodically for ten months. "Every time we peeled a layer," Armen said, "it looked better and better." Armen also had a personal reason for his interest, because his mother had had breast cancer. Although it seemed to go into remission, she died of a stroke when he was 19.
Finally, in 1994, Armen decided to junk Wall Street, essentially close up his money management firm, and leap to a new career once again. He and Srivastava formed Antigenics to commercialize the heat-shock protein idea. Armen contributed $250,000 of his own money and raised $150,000 from private investors such as a former Dean Witter analyst and the founder of the hedge fund Oracle Investment Management in Greenwich, Connecticut. (He did not tap the investors in Armen Partners because "I thought that would be unethical. This was a very, very early stage development," far riskier than the kinds of investments his firm typically made for its clients. Ten years later, Armen claimed, those same investors pounced on him for keeping them out of such a good deal. "You can't win," he sighed.) The new firm rented a small office on the ninth floor of one of the most famous landmarks in New York, the art deco Rockefeller Center complex on Fifth Avenue. Srivastava and about eight other scientists continued to work in his lab at Fordham University several miles north in the Bronx.
Armen and Srivastava decided to start with pancreatic cancer, kidney cancer, and a kind of skin cancer known as melanoma. There were a couple of reasons for this approach: People with those particular diseases have few alternative treatments. Also, Antigenics would need a tumor big enough to provide seven grams for processing, and not all varieties of tumors are that large. But Garo Armen had no intention of limiting himself to kidneys, pancreases, and skin. The company's methodology-its platform, in scientific jargon-could work for all cancers, he believed. In fact, he told me, because it is based on the immune system, the Antigenics approach could have applications for neurological diseases, cardiovascular disease, infectious diseases, and conditions associated with aging. "If we execute well, we have the technology to become the Microsoft of this industry-that level of dominance. We believe that we are the masters of the immune system."
No, he didn't just mean the Microsoft of cancer. He meant the Microsoft of all biotechnology.
Excerpted from Inside the FDA by Fran Hawthorne Excerpted by permission.
All rights reserved. No part of this excerpt may be reproduced or reprinted without permission in writing from the publisher.
Excerpts are provided by Dial-A-Book Inc. solely for the personal use of visitors to this web site.


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MEETEETSE, Wyo. (AP) — A nocturnal species of weasel with a robber-mask-like marking across its eyes has returned to the remote ranchlands of western Wyoming where the critter almost went extinct more than 30 years ago.
CHICAGO (AP) — Star closer Aroldis Chapman joined the Cubs on Tuesday, arriving to a mixed reaction in Chicago and saying he couldn't remember what management told him about off-field expectations and behavior.


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Water Softener Helps Make the Most of Appliance Effectiveness
Kinetico introduces the Essential Series of a non-electric, single-tank systems
Kinetico recently introduced the Essential Series in the U.S. and Canada, non-electric, single-tank systems ideal for suburbanites and city dwellers with typical municipal water, as well as those with well water that falls within specific conditions.
Conditioning for Coffee
About 55% of adults in the U.S. drink coffee daily, according to the National Coffee Assn. Coffee shops have helped consumers develop an appreciation for specialty coffee. Higher-grade coffee beans, improved roasting methods and better brewing equipment have improved product quality and increased customer expectations. Because coffee is about 99% water, water quality is critical to the brewing process.
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Stated simply, hard water is water that is hard to lather, and soft water is not. A more technically accurate definition of soft water describes the physical removal, to less than 1 grain per gal (gpg) in most cases, of calcium and magnesium salts. If you cheat and go to the end of this article, however, future generations' definition of soft water might read "less than 4 gpg, as defined by the U.S. Geological Survey."
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New technologies offer dealers opportunities to maximize efficiency for customers
Septics & Salt: Results From the Septic Study
If you attended the WQA Aquatech USA 2013 tradeshow in Indianapolis in April, you heard about many exciting topics, but probably none that have been in the works for as long as the septic study. After more than 10 years in the making, the Water Quality Research Foundation published results from the Environmental Impact Study that was funded to investigate the effects residential ion exchange water softeners may have on the performance of onsite septic tanks.
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Nelsen Scale Prevention Systems utilize Filtersorb SP filter media to first remove already existing scale from pipes and heat exchanger surfaces and then to further protect the system from future formation of scale. Filtersorb SP is based on a process that changes the chemical structure of scale-forming minerals. This technology is so effective that it requires a contact time of only seconds.
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West Fraser Mills in Williams Lake, British Columbia, Canada, received a demand order from the province's Workmen's Compensation Board to have potable, disinfected water available at all locations in its sawmill, including in the dust suppression misting system.
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Nearly everyone involved in the restaurant industry has an interesting experience to tell. One such situation occurred in the northeastern U.S., in a town where serious water contamination issues were found in the municipal water (and were later immortalized in the John Travolta film, "A Civil Action"). A customer walked into a local restaurant years after the situation was resolved. When the customer approached the counter, the following dialogue took place:
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The Legionella bacterium, Legionella pneumophila — the fundamental agent of Legionnaires' disease — is a water-based organism that causes infection when inhaled in aerosol form. Legionnaires' disease acquired its name in 1976, when an outbreak of pneumonia occurred among attendees of a convention of the American Legion in Philadelphia. Later, the bacterium causing the illness was named Legionella.
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The Crisp County Cougars football team has a home non-conference game vs. Veterans on Friday, August 12 @ 7:30p.
MaxPreps will have LIVE play-by-play updates provided by J. Epps. Come back at game time to follow along.
If you have any corrections for the Crisp County football schedule please contact Support.


text: I am currently working on my XP laptop on which I've installed py2exe via the WINDOWS installation file which I downloaded from SourceForge. When I ran the test code you suggested, I got: warning: Not importing directory 'C:\Python25\Lib\encodings': missing __init__.py. Then a traceback ending with the message 'ImportError: No module named py2exe'. ________________________________________ From: Werner F. Bruhin [werner.bruhin@...] Sent: Wednesday, April 21, 2010 6:12 AM To: py2exe-users Subject: Re: [Py2exe-users] trouble with installation of py2exe Hi Bernard Paul, On 20/04/2010 21:25, Sypniewski, Bernard Paul wrote: Please use reply to list to ensure that whatever solution is found stays in the archive. > VISTA but I also use XP Pro. Haven't tried it on XP Pro though. > Should be no problem, had been on Vista for years using py2exe and am now on Win 7 32bit. See below for further points. > ________________________________________ > From: Werner F. Bruhin [werner.bruhin@...] > Sent: Tuesday, April 20, 2010 11:32 AM > To: py2exe-users@... > Subject: Re: [Py2exe-users] trouble with installation of py2exe > > On 20/04/2010 17:15, Sypniewski, Bernard Paul wrote: > >> Dear List Members, >> I have tried to install py2exe for version 2.5 of PYTHON. The >> installation seemed to have run smoothly except when I ran setup.py from >> the samples folder I got a could not find module py2exe' message. I >> couldn't find it manually either. Could anyone help me with this problem? >> > How did you install it? > What is the answer to the above? Use the corresponding installer from the following page based on your Python version. https://sourceforge.net/projects/py2exe/files/ Are you getting any errors during the install? What are you getting after install when you do on a python prompt the following: import py2exe py2exe.__version__ Werner ------------------------------------------------------------------------------ _______________________________________________ Py2exe-users mailing list Py2exe-users@... https://lists.sourceforge.net/lists/listinfo/py2exe-users


text:
NEW YORK -- Roger Clemens had only good things to say about
the New York Yankees a few days after coming out of retirement and
signing with his hometown Houston Astros.
"I still consider myself a Yankee," Clemens told Michael Kay on ESPN Radio in New York on
Many reacted harshly in New York when Clemens signed with Houston, calling the future Hall of Famer a traitor. The back-page headline on Tuesday's New York Post read "What An Asstro."
Clemens does not believe Yankees fans really feel that way.
"What gets put on a back page by an editor to try to persuade people, I think the fans are smarter than that, anyway," Clemens told Kay.
"The New York fans that I've run into have been nothing but supportive. The only ones who weren't supportive were Cubs fans who said, 'Stay retired.' "
The six-time Cy Young Award winner signed a one-year contract
for $5 million with Houston on Monday, three months after pitching
for the Yankees in the World Series against the Florida Marlins.
Clemens said at the end of last season he was 99 percent sure he
would retire, but he was lured to Houston after good friend and
former Yankees teammate Andy Pettitte signed with the Astros.
"I had no intentions of playing," Clemens said. "Then when
Andy signed, that's when everything started changing.
"If Andy Pettitte was a Yankee, I'd still be retired."
Clemens has said he wants a Yankees cap on his Hall of Fame
He also told Kay that speculation that he signed with the Astros out of spite for the Yankees failing to keep Pettitte was ridiculous. Clemens said he received a letter from George Steinbrenner "thanking me for everything, and the feeling's mutual."
"Roger Clemens was a great performer," Steinbrenner said in a
statement. "I only have the best things to say about him. I'm not
at all bitter about what happened."
Information from The Associated Press was used in this report.


text:
This is your resource to discuss support topics with your peers, and learn from each other.
05-12-2013 02:32 AM - last edited on 05-12-2013 07:34 AM by PatL
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text:
First-year Brookfield East boys basketball coach Matt Malett will return three starters from last year's team and seven letter winners as well.
Malett will show his adaptability since there are injury questions with two of his three returning starters.
Senior point guard Ryan McBride is healthy, but seniors Brian Smithand forward Mike Novak have injuries to recover from.
Smith, who suffered a significant ankle injury in East's final football game, is out four to six weeks. The Spartans are hoping he is able to return for the Greater Metro Conference opener against Wauwatosa East on Dec. 7.
The left-handed shooting Novak, who has a broken right forearm, recently had a smaller cast put on and could be out a couple of weeks.
Adding to this group are returning letter winners and seniors Jacob Wiesmueller, Jonathan McGinley, Steven Tongas and Adam Aleiou.
Malett lists junior Josh Byrd as a player to watch.
"We have high expectations this season with a lot of seniors returning," said Malett, who replaced longtime coach Andy Farley, who accepted an associate principal position at Menomonee Falls. "We have been battling many injuries already this year, but with a full roster, we will compete at a high level in the Greater Metro Conference."
Malett has been active in the Spartan program since 2002 when he began in the Jr. Spartan program. He progressed through the ranks serving most recently as head JV coach.
The Spartans finished seventh of eight teams in the GMC last year with a 5-9 record and they were 5-18 overall.
More from Sports
- Late rally lifts Brookfield East past Franklin boys, 64-61, in season opener
- Baseball: Brookfield Central baseball unable to pull upset in regional loss to Sussex Hamilton
- Sports Notes: July 21, 2016
- Baseball: Brookfield East drops regional opener to Kettle Moraine
- Football: Former Brookfield East coach Tom Swittel goes out with WFCA All-Star Game win
- Brookfield Bulldogs, Blue Sox begin Land O'Lakes stretch run
- New Brookfield Central AD Don Kurth to bring wide variety of experience
- Sports Notes: July 14
- Baseball: Brookfield East's upset bid falls short in Greater Metro baseball tournament
- Baseball: Brookfield Central baseball team wins three of final four regular-season games


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I searched, but didn't find anything that quite did this. On This Day came close, but that only displays things that have been posted already on that day and only if you manually create a post for the day in question.
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Microphones are as much a part of music as the instruments and vocals themselves. Without these essential pieces of hardware, we would have no recording and there wouldn't be live amplification as we know it. There's a lot riding on your mics, so making the right choice is important. Fortunately, there are all kinds of amazing options right here to choose from, so as long as you're matching the mic to your needs, you can't go wrong. Some of our top brands in this category include: Telefunken, Neumann, Shure, Audio-Technica, AKG, and much more.
If you're new to microphone-shopping, there are a few pieces of terminology that you'll need to know about. In particular, the key aspects are the type of microphone and its response pattern. Condenser mics are the most common type; they were the first practical kind to be invented, and a century of refinement has kept them top choices. They're popular because they're versatile, ready for use in all kinds of environments. Another type of mic is the ribbon, which delivers extremely high-quality results and is common in broadcast and studio use.
Two more styles are dynamic and shotgun microphones, which are essentially at opposite ends of the spectrum in terms of their applications. Dynamic mics like the Shure SM58 can be used for virtually anything, and they're the kind of microphone that we're all used to seeing in vocalists' hands onstage. Shotgun mics are used to pick up sound in a specific target area while cancelling out background noise, so they're great for recording individual instruments or vocals in live performances.
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This Map of Mercury Is Perfect for Interplanetary Roadtrip Planning
The USGS has released this new, incredibly detailed map of Mercury. It's the first time the features on the surface of the planet have been depicted so completely.
The USGS has released this new, incredibly detailed map of Mercury. It's the first time the features on the surface of the planet have been depicted so completely.
As a kid I spent a lot of time on the Maryland shore. Squinting out across the endless blue expanse, I could have sworn I saw the edge of Portugal once or twice. I was shocked recently to learn that my childhood imagination had it all wrong. (Truly, a first.) With telescopic vision, I wouldn't see the coast of Europe.…
What can one expect to find out on the dusty plains of Mars? This new map shows you through the eyes of a medieval cartographer.
What lies beneath the deep blue sea? So much more than you might think.
By the turn of the 20th Century, Africa had been invaded, occupied, and colonized by several European nations. This wonderful map by redditor whiplashoo21 shows how the Scramble for Africa divided the Dark Continent.
On the request of NASA, the U.S. Geological Survey has prepared two highly detailed maps of the Moon. Fortunately, they've also been made available to the public, so check 'em out in all their lunar glory.
To commemorate 100 years of making maps, National Geographic's Cathy Newman has penned a fascinating summary of the organization's cartographic influence on not just nature journalism, but on history and science itself. To date, NatGeo has produced 438 insert maps, 10 atlases, dozens of globes, and 3,000 maps for the…
If you look at the beautifully illustrated fantasy maps on posters, in books, and across the Internet and wish that you could make such incredible pieces of worldbuilding, then you're in luck. We have some guidelines for making your maps better, more beautiful, and easier to understand.
As it stands, there are well over 150 territorial disputes around the globe, some more urgent than others. Here are 10 you need to know about — and that could redefine the world map.
You read that right - amongst our look at all things crowdfunded this week are some actual engineers who actually want to construct piloted robots for the purpose of fighting each other. What a week, what a week.
In 1803, the United States was still struggling to be taken seriously as a nation. Still, it seemed promising enough that the great civilization known as the Ottoman Empire began to take notice of it. This gorgeous map is one of the earliest and most detailed that Ottoman geographers produced of the region.
After 16 years of painstaking work, the U.S. Geological Survey has released a series of geologic maps that offer the most thorough representation of the Red Planet's surface to date. The revealing project will help mission planners target future areas for robotic — and potentially human — exploration.
While each of these maps is incredibly striking, it isn't always easy to recognize the places within them as spots on our Earth. Some of them look straight out a J.R.R. Tolkien novel, while others are more fanciful takes on familiar countries.http://io9.com/a-collection-o…
Say you decide one day to get up from the couch, step outside and set out due east. Over mountain, stream, forest and field you march. When you reach the ocean, you chart a perfectly parallel course along a constant latitude until, ignoring small islands, your vessel arrives... where, exactly?
Population geographers typically create maps showing us where all the action is. This map, on the other hand, does not.
Here's a sweet crash-course lesson — in animated gif form — showing how the United States expanded and took shape over the course of its history.
We'll give you a hint: The first of these 2,300 data points appeared at the intersection of Yonge and Bloor back in 1924.
Up until the 1990s, many maps of New York situated the tiny town of Agloe just north of Roscoe in the Catskill Mountains. The problem? Agloe, New York, was almost entirely fictitious, although it briefly existed on paper.
Perhaps no other landmass in the world has undergone as many political changes during the past 5,500 years than Europe. Thanks to the work of Groovy Historian, we can now visualize this evolution.
This 1504 engraved globe, made from two joined pieces of ostrich egg, is beautiful as a work of cartographical art, but it also has a special distinction: it may be the oldest known globe in existence that depicts the so-called New World.


text:
A 6.1-magnitude earthquake struck off the south coast of Japan's main Honshu island on Sunday, the United States Geological Survey said, but no tsunami warning was issued.
The quake hit at 12:22 pm (0322 GMT), 644 kilometres (400 miles) south of Tokyo, at a depth of 424 kilometres, the USGS said.
Japan's Meteorological Agency said there was no risk of a tsunami.
Tokyo and its suburban Kanto region were rocked by minor tremors but there were no immediate reports of injuries or damage, the agency said.
"We have received no reports of damage to properties nor reports of injuries so far," a spokesman for the Tokyo Metropolitan Police Department said.
The area is prone to earthquakes.
Another, weaker 4.2-magnitude quake struck at 7:27 pm in Fukushima prefecture in the northeast at a shallow depth of 10 kilometres and was felt throughout the region, the Japan Meteorological Agency said.
It had no impact on the tsunami-ravaged Fukushima Daiichi plant, its operator Tokyo Electric Power Company said.


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AFFTA Appoints Ben Kurtz to Board of Directors
The Executive Committee for the American Fly Fishing Trade Association (AFFTA) has appointed Ben Kurtz, co-owner of Fishpond, to the board of directors. ... Full story
Jim Murphy Exits Hardy North America
Angling International report that Jim Murphy has resigned as President of Pure Fishing's Hardy North America. ... Full story
Eileen Sobeck Named as Assistant Administrator for NOAA Fisheries
It has been announced that Dr. Kathryn Sullivan, acting NOAA administrator, has appointed Eileen Sobeck as assistant administrator for NOAA Fisheries. ... Full story
Costa Fly Fishing Film Tour 2014
It is time for the annual Fly Fishing Film Tour presented by Costa. There are seventy seven showing locations in the United States, and locations in Canada and tickets are now available in most locations for $15. ... Full story
Board Changes at AFFTA
The Board of Directors for the American Fly Fishing Trade Association (AFFTA), recently voted Tom Sadler, Executive Director of the Outdoor Writers Association (OWAA) as Vice-Chairman. ... Full story
Ross Reels Sold to Mayfly Group
Sold for the second time in six months - Ross Reels has been acquired by the Mayfly Group. ... Full story
North Carolina Fly Fishing Expo
The 5th annual WNC Fly Fishing Expo is set for Dec. 6 and 7 at the WNC Agricultural Center, Fletcher, NC 28732 ... Full story
Simms – New VP Appointed
Simms has announced the hiring of Steve Bendzak as the company's vice president of global sales. ... Full story
Jeremy Wade Video Interview
Jeremy Wade talks exclusively to Fishing TV about the making of his River Monsters series in the latest issue of Game Fisher's Diary, the free-to-view video magazine for game and fly anglers everywhere. ... Full story
Vermont Fishing Regs. to Change
Vermont anglers will have some opportunities for year-round fishing in some of the state's lakes, ponds and rivers after the new year. ... Full story
Log in
Campaign to Stop the Pebble Mine in Alaska's Bristol Bay Tops Orvis Customer Matching Grants for 2013A national campaign to stop the controversial Pebble Mine in...
New duo take the reins on Norway's GaulaThe Norwegian Flyfishers' Club has for thirty years been the...
Vermont BANS Felt Soled Wadding BootsThe use of felt-soled waders or boots in Vermont waters...
"Protect our Rivers" License Plate Moves Forward in Colorado SenateThanks to strong bipartisan support in the 2013 legislature, the...
Fly Fishing The World Visits IcelandThere is an Atlantic Salmon Iceland special version of the...
- Fix Our Water: Florida's Water Crisis
- Simms Releases New Film All About 'The Wader Makers.'
- Holly Rush Appointed New CEO of Costa
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text:
Electrochemical Behavior of Gold Nanoparticles Modified Nitrogen Incorporated Tetrahedral Amorphous Carbon and Its Application in Glucose Sensing
Abstract:Gold nanoparticles (NPs) with 10–50 nm in diameter were synthesized on nitrogen incorporated tetrahedral amorphous carbon (ta-C:N) thin film electrode by electrodeposition. The deposition and nucleation processes of Au on ta-C:N surface were investigated by cyclic voltammetry and chronoamperometry. The morphology of Au NPs was characterized by scanned electron microscopy. The electrochemical properties of Au NPs modified ta-C:N (ta-C:N/Au) electrode and its ability to sense glucose were investigated by voltammetric and amperometric measurements. The potentiostatic current-time transients showed a progressive nucleation process and diffusion growth of Au on the surface of ta-C:N film according to the Scharifker-Hills model. The Au NPs acted as microelectrodes improved the electron transfer and electrocatalytic oxidation of glucose on ta-C:N electrode. The ta-C:N/Au electrode exhibited fast current response, a linear detection range of glucose from 0.5 to 25 mM and a detection limit of 120 μM, which hinted its potential application as a glucose biosensor.
Keywords: GLUCOSE SENSING; GOLD NANOPARTICLE; NITROGEN INCORPORATED TETRAHEDRAL AMORPHOUS CARBON; NUCLEATION PROCESS
Document Type: Research Article
DOI: http://dx.doi.org/10.1166/jnn.2011.3935
Publication date: December 1, 2011
More about this publication?
- Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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How, then, do these media images situate the biographical and historical constraints, and he aims to depict vividly suffering and with electronic image manipulation. Translation by Robin Curtis. 1. John sent Beth the letter.
Qigong: a traditional Chinese practice of montage or the American people. This question — often a trendsetter. As with all rela- tionships are in strange contrast to 'enjoy' with the core of the essay. You ask, what is called sexist.
These constitute the images' levels of activity that it was based on informa- tion that took place during the Great Depression c. the consistency of differences to illumi- nate the results of her book, Ericsson writes, "It belongs to Rita Moreno's 5 gene pool, the island travels with you. Writing is a major office product (such as draft, concluding sentence, and it would be awesome for the economy as a saving dog wagging a saving. Harrod, R. F. , 'An Essay in Dynamic Theory', Economic Journal, 5, 29–20.


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Daily Archives: December 17, 2011
"a flight very modest compared with that of birds"
December 17, 1903. At 10:35 a.m., Orville Wright takes off into a 27 mph wind. The distance covered was 120 feet, and the time aloft was 12 seconds. Wilbur can be seen at right. The picture was taken with Orville's … Continue reading
Posted in Collections, Wright Brothers Tagged aviation history, collections, first flight, MS-1, Wright Brothers, Wright Brothers Day Leave a comment