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32 Reviews
We can't seem to find the vanilla milk that Horizon makes anymore (and that my daughter loves), so we found this recipe. Good advice about the alcohol level of real vanilla extract, it's pretty significant. I found Pure Vanilla Flavor Alcohol Free from Trader Joe's. We put 2 teaspoons in, not one. Good!
Simply deelicious. I used soy milk with just a touch of sugar since it was already pretty sweet on its own. I also had this hot! It's wonderful as a hot drink. Mmm! Thanks!
This was very good! I did use 1/2 tsp. imitation vanilla because thats all I had and i boiled the milk and it was great. Tasted exactly like starbucks steamed milk!! Will make again!!
My 5 year old just thought this milk was strange tasting. My husband thought it was ok. I thought it had potential to taste like snow cream! I would make this for myself but next time I will put it in my magic bullet with a little more splenda (about 1/2 tbs. more) with some ice. Good flavor to me...just would like a little sweeter with some ice to make like snow crea (one of my childhood favs)!!
My son has loved this for a long time, but I always use imitation vanilla for him (and a little nutmeg too) He likes it warm before bedtime.
I have been doing this for years but have never added sugar. My kids also like coconut extract in place of the vanilla - yum!
wow! I have hated plain milk pretty much my entire life and could never drink a glass by itself. this recipe changes that! I can drink this whole glass and actually LOVE it! tastes like a vanilla milk shake. great stuff! thanks for a keeper!
This is great hot, it's like a steamer. Not just for kids!!
Pretty good stuff. I just made this for myself to try. I'll stick to the sugar free chocolate milk mix for my kids, and I doubt I'll make this again. But it was worth trying!
Made this milk to use in Peachy Peach smoothie #134652. My husband and granddaughter both had a glass of this milk and really liked it. Thanks Pantry Chef Starkey. Bullwinkle.


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"When we have a skilled work force, then they can compete for jobs and have an opportunity to impact the regional economy."
Related quotes
"You've got to find what you love.Your work is going to fill a large part of your life, and the only way to be truly satisfied is to do what you believe is great work. And the only way to do great work is to love what you do. If you haven't found it yet, keep looking. And don't settle."
"We cannot force others to behave differently if they disagree with us; but if we change what we are saying or doing they will respond differently. - Nabil N. Jamal"
"Mrs. Eckert was a strong force in my life. She helped to develop in me a strong work ethic. She was a demanding teacher, but I didn't mind doing what she assigned. She taught her students to work hard and to accomplish whatever they set out to do, in spite of the obstacles. She taught us to never back down when we knew what we were doing or saying was right. She was very much a people person - she didn't forget anyone."
"Now we are in the jobs revolution. We are living history. And we must have a skilled work force if we are going to compete."
"We're very proud to be offering jobs to people who don't typically get into the work force -- disabled individuals, retirees, stay-at-home moms."

subset: commoncrawl


text:
Infinity Hold
The complete and unabridged Infinity Hold trilogy: Infinity Hold, Kill All The Lawyers, and Keep The Law. In a world of terrorists, murderers, and criminally insane, one man rises to become the world's first police officer and the guardian of their most precious possession: The Law. Three full novels, the complete saga from before the landing to Bando Nicos's murder trial. Kill All The Lawyers: First time in book form. Keep The Law: First publication!
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Acetrax launches VOD with Panasonic
Acetrax has officially launched its video on demand service through web connected Panasonic TVs and it is claiming that it is "Europe's first connected TV service enabling movies for purchase".
What it means by this is, unlike services such as LoveFilm on Samsung and Sony TVs, Acetrax users can buy the titles they wish to keep rather than just renting them.
Pocket-lint went down to the launch in central London to find out how, and give the service the once over.
When you buy a film it is stored in a digital locker. But, with Acetrax you can also view films through your PC or Mac. With these you actually get a WMV copy of the movie rather than just streaming it. You can, therefore, have an actual digital copy stored on your machine, but still stream a copy from your digital locker on your TV.
You can also rent movies, just like LoveFilm. At the launch there are about 2000 movies available, as well as some TV series. Prices range from £1.49 to £3.49 for rentals and up to about £10.99 for a purchase.
Films are streamed using the VC1 Advanced codec which gives "DVD quality" according to Acetrax CMO, Leslie Golding. We're not going to disagree with him - we looked at a few films and they all looked very crisp.
At the moment the service works with any Panasonic internet connected TV featuring VieraCast. In the coming months it will also be introduced onto web-connected Blu-ray players as well.
You can have up to four devices linked to one account, so for example you could have your main Panasonic Viera TV downstairs, a Blu-ray connected to an older TV of any model in the bedroom, and still have it available on two other PCs or Macs.
Everything is wrapped in a Microsoft-powered DRM and rentals expire within 24 hours from when your first hit play - the digital locker clearly shows you how long you've got left as well as telling you which of your titles are rentals and which ones you own.
Golding allowed us to have a little play with the system and it was very responsive, we have to say. It was also pretty quick as well considering it was demoed using a shared Wi-Fi connection rather than a plugged in Ethernet link.
It's easy enough to navigate between different sections such as film genres, new releases and the most popular titles, and you can also access a film's synopsis and view the trailer before you commit to buying or renting.
The service is simple, anyone who has used an EPG will find it a doddle, and most importantly it is fast. There isn't too much waiting around for images or details to load, which is impressive for a completely web based service. When you click to buy or rent a title there is around a 2-minute wait before it begins - Golding said this was a DRM and licence check delay rather than a buffer period.
We asked him if the service was exclusive to Panasonic, and he told us it wasn't and that it was also speaking to other companies with a view to expanding. He was keen to stress however, how influential Panasonic was in the design process.
"We're not launching a separate app on a platform here", he said. "It's like Apple and iTunes, the two come as one".
One platform the service will not be hitting, unfortunately, is your console - whether that be Xbox 360 or PS3. Golding said that, within Europe at least, Sony and Microsoft are not interested in opening up their platforms for third parties.
That's a shame because it looks like a really good service and the more platforms it appears on, the better.
House of Cards comes to Sky in the UK
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Excellent Service, speedy delivery


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Skip to comments.Sarah on Fox
Posted on 04/13/2012 7:36:29 PM PDT by Aria
Sarah is on FOX right now for a special about gas prices. Didn't see a thread on this.
Oh how I love this woman - no teleprompter in sight - facts - love of country- optimism - practical solutions. She has it all.
So do I. However, she did an O'le and let Romney in past into the nomination. I have a hard time looking at her than just more than a pundit like the Huckster.
HUH? She "LET Romney in past into the nomination"????? Other than I'm not sure this makes sense...it still doesn't make sense.
She supported Newt and said so. Is she supposed to control all the votes?
So far I haven't seen much new.
Can you rephrase that? What did she say exactly about romney?
She would have had to beat The Democratoc party AND the GOP infrastructure.
What I meant was, if she had run, she would have won the nomination. Period. Thereby stopping Romney or anyone else. That's what I meant.
If she had run, she would have won and stopped Romney. That's what I meant.
I'll say this, Reagan getting the nomination was anomaly....to the GOP Establishment. They determined after that to never let a true conservative ever get through again, who they consider rebels. They have been after Sarah in so many ways, seen and unseen to us! We don't know yet what they were up to last year
Yeah. So? I don't know of anyone who's ever run for President with a "Guarantee" warranty?
With all due respect to Steve Jobs, the Palin announcement was far more tragic, as far as I'm concerned.
So far I havent seen much new.
For those who have been following this, not too much new.
For the masses who haven't (like my two college friends who watched), rather insightful...they liked it.
Jobs could have been a real American Icon — if he built the darned things in America...
My thoughts too.
With all due respect to Steve Jobs, the Palin announcement was far more tragic, as far as I'm concerned.
I think she got an offer she could not refuse.
I'm glad your friends watched...there is so much total BS out there that I bet simple facts and perspective were refreshing - not to mention the obvious that Sarah isn't what the left wants everything to think.
Hannity: (8:40min:seconds to 8:46 ) Alright, Lets talk about the campaign and your convinced Romneys it now? Do you think its pretty much over?
Palin(8:47 9:09 ) Well let me put it this way, I dont want Newt to drop out, I dont want Ron Paul to drop out, because I want debate still on the ideas that both of the other candidates have been able to espouse and explain to the country, I want Ron Pauls message about cutting the budget, about the economic woeful times that we are in and what we can do about it I want those to continue to be discussed and Newt has some good ideas too.
Hannity: (9:09-9:22 ) Are you convinced, because you spoke about this at an earlier time during the primary, are you convinced as to time has gone on that governor Romney will govern as a solid strong conservative or do you still have doubts?
Palin: (9:23-9:37 ) I am convinced that governor Romney, if he is our nominee and if he is elected president, he will know to surround himself with those that will inherently know to go right, to err on the side of smaller, smarter government and that gives me a lot of confidence.
I watched the interview, too.
Even when he tried, he couldn't get her to say that of course Mitt would be the nominee.
The primaries are not even over, yet.
Best would be a Sarah/Newt combo.
That's on a par with everything being Bush's fault - wrong target.
Would have loved her running, but won't second guess her either - she's in a far better position to know what to do than we are.
Damn spell checker! SLIMMED should be SLIMED (as in Ghost Busters).
Lucky I caught it last night.
The "multi-pass" speculator explaination explained a very big missing piece of what is behind soaring gas gas and diesel prices.
Of course nobama isn't saying anything, its part of his inner network of big money folks enabled to reach into everyone's back pocket.
Anyone think Mitt plans on disrupting that cash-cow?
>>...If she had run, she would have won and stopped Romney. Thats what I meant...<<
I admire your optimism!
However, the GOP has rearranged the deck-chairs on our Titanic so that any & all favor and bias in the campaign process falls to Romney. I doubt Palin could have impacted Romney's support significantly enough to change the outcome desired by the GOP. I doubt an exact clone of Reagan could do it considering the way the deck has been stacked for Romney by the GOP, pundits, msm, etc.
I think Palin was shrewd enough to recognize this early on. I place her head and shoulders above the sorry slate of candidates we had to choose from, but I also think she has *FAR* better insight into the process than I ever will and she chose not to run according to her assessment of the situation. I can't hold it against her, but opinions will vary...
Thanks. Yout opinion is just as good as mine. I just don't believe that she chose not to run because of the establishment supposed-love with Mitt.
I would prefer a PALIN/BOLTON ticket.
There are as mnay preferred combinations as there are conservatives.
And the ,' may way or the highway', is why we have lost the culture wars.
Liberals take the long view of history to attain their goals.
We are all or nothing.
Palin deciding not to run destroyed our momentum from 2010. we were on top of the world...for alittle whille (like van halen)
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Kaiser Saucy
The Victorian Gothic opulence of the Johnson performing "Small Print" live at Tommy Flynn's in Camden, London, UK on 13th February 2009. Find out more at: myspace.com/legojohnson youtube.com/legojohnson
Facebook Group: Lego Johnson
Join up now.
Camera work by: Giuseppe Circelli, Marcio Bertoncello & Pietra Mello-Pittman. Many thanks to them &, of course, everyone else who attended.


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/// Why Tumblr Won't Move Yahoo's Needle
May 24, 2013 | All Things Digital
When Yahoo Inc. Chief Executive Marissa Mayer announced that the Internet giant would spend $1.1 billion to acquire blogging site Tumblr, she promised not to "screw it up." Maybe the young chief should have instead emphasized what the six-year-old fledging startup can do for Yahoo. The answer appears to be not much. Read the rest of this post on the original site »
Originally posted here:
Why Tumblr Won't Move Yahoo's Needle
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Indeed - San Mateo, CA
Responsibilities Drive growth by selling pay-per-click advertising (PPC) services to small-to-medium sized employers (SMB) Develop relationships through phone,...
Piacere - San Carlos, CA
Required license or certification:. We are looking for an energetic, outgoing person who can utilize time management skills, organizational skills and who can...
Inside Sales Representative
BroadVision - Redwood City, CA
§ Taking inbound calls and follow-up on inbound web leads. This is an opportunity to make a significant contribution to a leader in the rapidly growing...
TasteVin Wine Bar & Bistro - San Carlos, CA
Responsibilities include doing dishes, cleaning and janitorial tasks, helping the kitchen with cheese and cold plates assisting FOH when needed....
Open House
The Floor Store - San Carlos, CA
We will be conducting face to face interviews from 4pm to 7pm on Tuesday August 2nd. The Floor Store in San Carlos is holding an Open House for our two open...
Sigona's Farmers Market - Redwood City, CA
No calls about this job, please. Customer Service- answer questions for customers. Cashier – PT/FT Starting at $12/HR more if you have experience....
Fraud Analyst
Signifyd - San Jose, CA
Collaborate with cross-functional groups such as Customer Support, Product Management, and Engineering to enhance tools, data sources, system functionalities,...
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As an Equal Opportunity Employer, Fast Retailing does not discriminate against applicants or employees because of race, color, creed, religion, sex, national...
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We have a wide range of customers from homeowners to designers to contractors. Bayshore Supply is a growing electrical, plumbing and HVAC distributor....
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FedEx Express - Menlo Park, CA
Must be licensed for type of vehicle assigned. Answers customer questions on FedEx features of service and keeps customers informed about the company and its...


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Elegy Beach Hardcover – November 3, 2009
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Learning about this new world was a lot of fun, as was meeting the characters along the way, thanks to Boyett's dry wit. He is not satisfied with using standard fantasy elements, which would be fine with many readers; he breathes life into what could have been clichés by giving plausible explanations for why things are the way they are. It makes for a very rich and robust story.
A rich read that's a page-turner at the same time - I know that any lover of fantastic journeys would love this book.
I think this book could stand on its own, but I am such a huge fan of Ariel that I have to suggest reading that one first. Both are special in their own way.
The characters in this book are different from Ariel, but I think that's ok - its great to bring out new characters. They are the descendants from the first book and they are attempting to understand, control and I guess you would say... organize or bring structure to the new "magic" that inhabits the world now. Sort of like scientists have done with physics in our own past. Very clever. I don't want to say too much more or give spoilers. Suffice to say if you liked Ariel, you will enjoy this greatly.
The author's writing is fresh & enjoyable, a really great read!
Elegy Beach rejoins Pete and Ariel decades later, when they're older, wiser, and a bit more jaded. Interestingly, the story isn't told from their perspective, but from that of Pete's son. It's an inspired choice, one that helps Boyett create a compelling, poignant, beautifully nuanced novel by letting us see these familiar characters through fresh eyes.
Boyett is just as gifted with language as he's ever been, and his well-crafted plot is fairly airtight--no small task for a sci-fi/fantasy book, especially one this long. In fact, I'd argue that his talents have grown over the past 30 years. It may help to (re)read Ariel before tackling Elegy Beach, but it stands on its own, too.
The novel picks up 25 or so years after the first story ended. Peter has settled down on the West Coast, has raised a son, lost a wife and is now living out his years in one of the communities which have banded together to survive in the post-Change world. His son, Fred (yes, named after his sword), is learning how to be a caster. He seems to have some skill, but like most young people is looking for shortcuts.
He and his friend, Yan, seem to have "cracked the code" for creating powerful magic. Yan embarks on a quest to magnify and solidify his power, and Peter (along with Yan's father and Peter) are forced to go after him to try to stop what may be yet another doomsday for the world.
I'd recommend re-reading Ariel. While written 26 years before Elegy Beach, it still holds up well.
I felt that many of the issues and questions which were raised in the first book are, if not resolved, at least discussed. This is not to say we find out what caused the Change itself, but more related to the motivations and actions of the characters who we were introduced to in the first book.
Ariel was a book which I had read a long time ago, but the story and characters had remained with me. I thoroughly enjoyed this book, and finishing it I felt a sense of closure. I actually wouldn't mind another installment, to see what Fred ends up doing with his life.
Ariel became a cult classic, and now, 25 years later, Boyett finally returns to the world of The Change with the long-awaited sequel, Elegy Beach.
Elegy Beach picks up about 20 years after the events of Ariel, and shifts to the West Coast, where Pete's son, Fred, is a young man growing up to be a talented caster. He and his best friend, Yan, try to apply scientific principles to the study of the magic that infuses their world, and for Yan, a taste of power only fuels his desire for even more.
The events that unfold next can be summed up in a scene where Fred thinks to himself, "In the air above the mountains in a battered gondola of a wounded airship on my way to confront my former best friend holed up in the ruin of a former castle while he perfects the casting that will reinstate the old world's order I am talking to a unicorn about whether the centaur following us is carrying my captured father. Um, ok...Read more ›
Most Recent Customer Reviews
I recommend reading Ariel first, just because it also is a great read. I really liked the idea of a world with magic adding in when most other end of the world novels are just... Read morePublished 5 months ago by Walt Fitzharris
Great follow up to Ariel. I have read this book multiple times it is great!Published 6 months ago by Ariel Lynn McFarland
I picked up this book and "Ariel" at a used bookstore awhile ago. I'd never heard of "Ariel", but generally like post-apocalyptic fiction. Read morePublished 20 months ago by R. Douglas
A friend gave this to me, and I began it very slowly, but became quite passionate about reading it as I advanced through the story. Read morePublished 20 months ago by Marc Johnson
The original book Ariel was amazing idea for a story. Earth suddenly experiences a shock where half the laws of nature stop working. Read morePublished on March 27, 2014 by Gary
Often times you see a movie or read a book and -even though the story wraps up nicely- you are left with a sense of longing. Read morePublished on March 11, 2014 by Since1791
I read Ariel when it came out back in the day -- never realized at the time, until after I read the afterword, that the author was as young as I was at the time. Read morePublished on March 3, 2014 by M. Peterson
Ariel is only the best fantasy book ever written-took a long time for the sequel Elegy Beach to come out-am glad it did-it is just as good-it will leave you wanting for more-if you... Read morePublished on February 1, 2014 by RMF
Boyett not only tells a story but turns its heart inside out. Please...write more! Also, check out The Architect of Sleep--too good for words.
Katherine M.Ozbirn


text:
Hypoxia and oxidative stress markers in pediatric patients undergoing hemodialysis: cross section study
Tissue injury due to hypoxia and/or free radicals is common in a variety of disease processes. This cross-sectional study aimed to investigate effect of chronic kidney diseases (CKD) and hemodialysis (HD) on hypoxia and oxidative stress biomarkers.
Forty pediatric patients with CKD on HD and 20 healthy children were recruited. Plasma hypoxia induced factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) were measured by specific ELISA kits while, total antioxidant capacity (TAC), total peroxide (TPX), pyruvate and lactate by enzymatic/chemical colorimetric methods. Oxidative stress index (OSI) and lactate/pyruvate (L/P) ratio were calculated.
TAC was significantly lower while TPX, OSI and VEGF were higher in patients at before- and after-dialysis session than controls. Lactate and HIF-1α levels were significantly higher at before-dialysis session than controls. Before dialysis, TAC and L/P ratio were lower than after-dialysis. In before-dialysis session, VEGF correlated positively with pyruvate, HIF-1α and OSI correlated positively with TPX, but, negatively with TAC. In after-dialysis session, HIF-1α correlated negatively with TPX and OSI; while, OSI correlated positively with TPX.
CKD patients succumb considerable tissue hypoxia with oxidative stress. Hemodialysis ameliorated hypoxia but lowered antioxidants as evidenced by decreased levels of HIF-1α and TAC at before- compared to after-dialysis levels.
In chronic kidney diseases (CKD), as a worldwide public health problem, there is a functional loss of renal glomeruli caused by glomerular or interstitial renal diseases
Hypoxia is a state of reduced oxygen pressure below a critical threshold, which restricts the function of organs, tissues and cells. A decrease in oxygen tensions of the kidney was demonstrated in a number of experimental models of CKD. This led to the broad recognition that chronic cellular hypoxia of the kidney is the final common pathway in the progression of CKD leading to eventual kidney failure
Genes activated by HIF can be schematically classified into three functional groups that could halt CKD progression. (1) Proteins participating in erythropoiesis, thereby increasing tissue oxygen delivery, e.g., erythropoietin, transferrin, transferrin receptor, heme oxygenase-1. (2) Proteins that increase local oxygen delivery to tissues, e.g., inducible nitric oxide synthesis and vascular endothelial growth factor (VEGF). (3) Proteins required for adaptation to anaerobic cellular metabolism: glucose transporter-1 and most glycolytic enzymes
VEGF, a 35kDa molecule, is a chemoattractant that enables the homing of regenerative endothelial cells into local vascular lesions
Oxidative stress is an imbalanced generation of reactive oxygen species (ROS) vs. the counteracting antioxidants. In CKD, such stress is multifactorial. Uremic toxins, interactions between circulating mononuclear cells and bioincompatible dialyzers or contaminated dialysate, and infections, can act as triggers
To our knowledge, there are a few studies addressing systemic oxidative stress and cellular hypoxia biomarkers together in children with CKD on regular hemodialysis. We suggested that impaired response to tissue hypoxia and oxidative stress would be major determinants to clinical outcomes in such patients. This cross-sectional study aimed at assessing the effect of CKD as well as maintenance HD on plasma oxidative stress markers [total anti-oxidant capacity (TAC), total peroxide (TPX) and oxidative stress index (OSI)] and standard hypoxia biomarkers [lactate, pyruvate and lactate/pyruvate (L/P) ratio, and VEGF] as well as HIF-1α in CKD pediatric patients before and after HD session. HIF-1α, the key regulatory cellular hypoxia effector is investigated for the first-time to our knowledge as a plasma biomarker. The relationship among these markers will be statistically analyzed.
Study groups
Forty children and adolescents with CKD (25 male and 15 female) on maintenance HD with an age range of 6–15 years [12.83±1.89 years, mean+/− standard deviation (SD)] were voluntarily recruited to this cross section study at the Pediatric Nephrology and Dialysis Unit, Assiut Children University Hospital, Assiut, Egypt, during the period from January 2010 to September 2010. At the time of the study, all the patients were on regular three HD sessions per week; each time for 3–4 h (total 12 h weekly) for more than 3 months with polysulfone dialyzing membranes, after creatinine clearance had fallen below 8–12 mL/min and/or pharmacological treatment and diet had proved inadequate to control clinical symptoms. The mean dialysis duration was 2.18±1.36 years (range: 1–7 years). All patients were on dietary protein restriction, 1 g/kg body weight per day. The dialysate used was a standard ionic composition and bicarbonate-based buffer (Na+ 138 mmol/L, HCO3
- 36.6 mmol/L, K+ 1.5 mmol/L, Ca2+ 1.25 to 1.75 mmol/L, Mg2+ 0.75 mmol/L) for all cases. The blood flow was 120–150 mL/min and dialysis fluid was used at a flow rate of 240–300 mL/min. Vascular access was arteriovenous fistula in the upper limbs. The causes of CKD were: urolithiasis (
At the time of entry, none of the participants was receiving non-steroidal anti-inflammatory drugs, immunosuppressive therapy or any other drugs that might have interfered with the oxidative stress, and none had uncontrolled hypertension or a history of seizure. Patients with infections, vasculitides, or respiratory, metabolic and hepatic diseases were excluded. Control subjects were on a normal diet without vitamin supplementation and were free from any infection or medication. Routine analyses showed that controls had normal renal function tests and no disorders of lipid metabolism. Both patients and controls were nonsmokers. The study was approved by the local ethics committee and was conducted in accordance with the Declaration of Helsinki and informed consent was obtained in every case from their legal guardians. Demographic, clinical and biochemical characteristics of all participants were reported.
Laboratory investigations
Blood samples (5 mL) with and without EDTA/sodium fluoride as anticoagulant were obtained via venipuncture after the participants had fasted overnight (between 8.30 P.M. and 9.30 A.M.), and serum and plasma were separated and aliquot frozen at −80°C till used. In HD patients, venous blood samples were drawn immediately before and after hemodialysis session. Baseline laboratory investigations were carried out for all patients and controls including complete blood count, serum urea and creatinine, arterial pH, arterial blood gases and infection screening, which included blood and urinary cultures by standard methods. Arterial pH, PaO2, PaCO2, HCO3 - were determined using a pH/blood gas analyzer on anaerobically collected blood drawn in ice-cold, heparinized glass syringes.
ELISA assays were utilized to measure each of VEGF (Cat# ELH-VEGF-001, RayBiotech, Inc, Norcross GA 30092 - lower detection limit is 10 pg/mL) and HIF-1α (Cat# DYC1935-5, R&D Systems, Minneapolis, MN 55413, USA - lower detection limit is 3 pg/mL) with specific capture and biotinylated detection antibodies and Streptavidin-Horse Radish Peroxidase/tetramethylbenzidine as the detection system. Total antioxidant capacity was estimated according to the colorimetric method of Koracevic et al.
Data analysis
Statistical Science for Social Package (SPSS Inc, USA) software computer program version 12 was used for data analysis. Data were presented as mean -/+ SD and minimum - maximum or number and percentage (n, %) as appropriate. For comparison of two groups the nonparametric test for independent variables and paired and unpaired student "t" test for parametric variables were used while, comparisons of multiple groups were done using one-way analysis of variation for parametric variables. Spearman's correlation test was used for parametric variables within each group. For all tests, a probability (
Total antioxidant capacity was significantly lower while TPX, OSI and VEGF were significantly higher in patients at before- and after-dialysis session than healthy controls. Lactate and HIF-1α levels were significantly higher (
At before-dialysis session, duration of disease positively correlated with HIP-1α (r = 0.677,
Relative hypoxia, as the major activator of hypoxia-inducible factor, is detectable in chronic kidney disease tissues irrespective of etiology and is thought to result from a combination of structural and functional changes that include; decreased peritubular blood flow associated with glomerular injury, capillary rarefaction, vasoconstriction, luminal narrowing of atherosclerotic vessels, increased oxygen demand from hyperfiltration and tubular hypertrophy, limited oxygen diffusion as a consequence of extracellular matrix expansion, and renal anemia
In this study, HIF-1α was investigated as a plasma biomarker for the first-time world-wide particularly in CKD. At before-dialysis session, plasma VEGF positively correlated with each of pyruvate, and HIF-1α. The positive correlation between HIF-1α and VEGF is expected as VEGF gene is HIF-1α-inducable to increase local oxygen delivery to tissues. This indicates the utility of HIF-1α as plasma biomarker of cellular hypoxia in CKD that reflects the disease outcomes. However, a reparative role for the induced HIF-1 in CKD is questionable in light of blockade of the induction of erythropoietin by the accumulating uremic toxins
The role of ROS and/or decreased antioxidant activity in the development of CKD complications, such as atherosclerosis and related cardiovascular disturbances is well-established
One reason for oxidative stress in patients with renal failure is the underlying disease itself. Renal toxicity and immunological disorders of the kidney result in an elevated formation of ROS which is active in the pathogenesis of kidney disease. However, treatment procedures were also shown to induce oxidative stress. During HD, incomplete correction of the uremic toxicity together with the untoward effects of dialysis, malnutrition and the progressive worsening of clinical condition, can lead to oxidative stress. The later is caused by an abnormal production of oxidants including ROS and uremic toxins with pro-oxidant function correlating defective antioxidant protection. Bioincompatibility of dialysis membranes represents an important source of ROS. Losses of antioxidants via dialysis are the factors that may be responsible for the imbalance between pro-oxidative and antioxidative mechanisms in HD patients
However, Drai et al.
In our healthy controls, L/P ratio positively correlated TAC; HIF-1α positively correlated with each of L/P ratio and TAC; VEGF positively correlated with each of TPX and OSI. At after-dialysis, HIF-1α negatively correlated with each of TPX and OSI. In this respect, several reports showed an inverse correlation between MDA serum concentration and hemoglobin in the blood of HD patients
There is considerable cellular hypoxia in pediatric patients with CKD that leads to oxidative stress. HD leads to decrease hypoxia and increase loss of antioxidants as evidenced by decreased levels of HIF-1α and TAC at before- compared to after-dialysis settings. The resulting oxidative stress could contribute to the long-term complications in uremic patients. In compensation, VEGF levels increases to improve oxygen delivery to hypoxic tissue. Further longitudinal studies are necessary to establish the relationship between plasma markers of hypoxia and oxidative stress and clinical outcomes of CKD on maintained HD - particularly utilizing interventions such as antioxidant supplements and improved aeriation. Longitudinal studies are mandatory since preliminary data showed that low blood gases and hemoglobin correlating with high hypoxia biomarkers are fatal.
Limitation of the study
Our study has several limitations that necessitate further investigations. By nature, a cross-sectional study would not derive a cause/effect conclusion among the investigated parameters and CKD and/or HD. Second, blood gases, pH and bicarbonate were analyzed before dialysis only because of local limitations. Third, the limited number of participants did not allow statistically meaningful subgrouping according to underlying cause of CDK.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
The authors EAH, TBA, AOM, ARA and THM have made substantial contributions to the concept and design of the study, the acquisition, analysis and interpretation of data, and in drafting the manuscript or critically revising it for important intellectual content. The authors TBA, AOM and THM measured the estimated biochemical parameters and ARA collected the data sheets and blood samples from patients. The authors have also given final approval of the version to be published. Each author has participated sufficiently in the work to take public responsibility for appropriate sections of the content. All authors read and approved the final manuscript.
The authors appreciate the collaboration of the subjects and their parents for their participated in this study.
National Kidney Foundation clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification
Endothelium-dependent vasodilatation and distensibility of large arteries in chronic haemodialysis patients
Peritubular capillary regression during the progression of experimental obstructive nephropathy
The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration
Mammalian oxygen sensing, signaling and gene regulation
HIF-1 and hypoxic response: the plot thickens
Role of the hypoxia inducible factors HIF in iron metabolism
VEGF increases engraftment of bone marrow‑derived endothelial progenitor cells (EPCs) into vasculature of newborn murine recipients
Impaired angiogenesis in the aging kidney: vascular endothelial growth factor and thrombospondin‑1 in renal disease
Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling
HIF in kidney disease and development
Characteristics and effects of inflammation in end-stage renal disease
Oxidative stress, inflammation and early cardiovascular damage in children with chronic renal failure
Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency
Lipid peroxidation and antioxidant enzymes in children with chronic renal failure
Beneficial in vitro effect of N-acetyl-cysteine on oxidative stress and apoptosis
Method for the measurement of antioxidant activity in human fluids
Increased oxidative stress in patients with hydatidiform mole
Measurement of the total antioxidant response in preeclampsia with a novel automated method
Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics
Acid–base balance and oxygen affinity of hemoglobin in patients on maintenance dialysis
Biochemical tissue monitoring during hypoxia and reoxygenation
HIF-1 regulation: not so easy come, easy go
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
Human nephrosclerosis triggers a hypoxia-related glomerulopathy
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner
Dysregulated oxygen metabolism of the kidney by uremic toxins: review
Twist is a new prognostic marker for renal survival in patients with chronic kidney disease
Salivary and plasma analysis of oxidative stress biomarkers in end stage renal failure patients
Adaptation of glutation-peroxidase activity to oxidative stress occurs in children but not in adult patients with end-stage renal failure undergoing hemodialysis
Alteration in plasma total antioxidant capacity, cardiotoxic lipid peroxidation product and C-reactive protein: a possible explanation for the increased cardiovascular risk in children on hemodialysis
Erythrocyte defence mechanisms against free oxygen radicals in haemodialysed uraemic children
Influence of dialysis on plasma lipid peroxidation products and antioxidant levels
Oxidative stress markers and C-reactive protein in end-stage renal failure patients on dialysis
Oxidative stress influences CC-chemokine levels in hemodialyzed patients
Influence of initiation of maintenance hemodialysis on biomarkers of inflammation and oxidative stress
Effect of haemodialysis on the oxidative stress and antioxidants in diabetes mellitus
Oxidative stress in children with kidney disease
Mononuclear leukocyte apoptosis in haemodialysis patients: the role of cell thiols and vitamin E
Effects of dialyser and dialysate on the acute phase reaction in clinical bicarbonate dialysis
Oxidants and antioxidants in long-term haemodialysis patients
Plasma total antioxidant capacity in hemodialyzed patients and its relationships to other biomarkers of oxidative stress and lipid peroxidation
Effect of dialysis on plasma total antioxidant capacity and lipid peroxidation products in patients with end-stage renal failure
SIRT3 Is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the warburg effect, and carcinogenesis
Pre-publication history
The pre-publication history for this paper can be accessed here:


text:
Wine Details
Wine Description
(From 2012 Vintage) This wine has a bright color pale yellow with green highlights. The first nose, quite discreet, this delicate notes of fruit and white flowers. After swirling, the nose reveals, expressive, complex, rich with an explosion of yellow fruit, peach, apricot, mango, citrus (grapefruit), sweet spices, anise, caramel. The nose is both ripe and fresh reflects the good weather of the late maturation. On the palate, we find that delicate balance between maturity and freshness that gives the wine a beautiful balance: maturity, wealth, power, quickness. The attack is then stretched mouth widens, becomes dense, creamy, oily.
Winemaker's Notes
(From 2009 Vintage) Château Smith Haut Lafitte white 2012 offers a bright, vibrant pale yellow colour with green hue. The first nose, quite discreet, offers delicate notes of white fruits and flowers. Through aeration the nose open up to become very expressive, complex, rich with an explosion of yellow fruits, peach, apricot, mango, citrus fruits (grapefruit), sweet spices, star anise and even a hint of caramel. This nose, both mature and refreshing, reflects perfectly the good weather conditions at the end of grape maturation. On the palate, the subtle balance between acidity freshness and fruit maturity appears clearly to give the wine a harmony of ripeness, richness, tension and vivacity. The attack is tense, then the mouth enlarges to become dense, more unctuous with a sense of fatness.
Robert Parker(From 2009 Vintage) Rating: 100/100 - As reviewed by Robert Parker on 02/21/2012
Wine Spectator(From 2009 Vintage) Rating: 96/100 - As reviewed by Wine Spectator on 01/11/2012
Robert Parker(From 2011 Vintage) Rating: 89/100 - As reviewed by Robert Parker on 04/21/2014
Connoisseurs' Guide to California Wines(From 2005 Vintage) The evident ripeness and outwardly juicy fruit that defines much of this bottling are not the stuff of classic Bordeaux, and, while they may be anathema to some, the rest of us will find plenty of pleasure in the wine's ongoing richness and depth. There are ample tannins at work, to be sure, but they are never abrasive or overly tough, and, as tasty as the wine is early on, it seems a very good bet to gain in complexity and polish if allowed to rest for another four to six years.
Wine Advocate(From 2006 Vintage) Rating: (93-95) - As reviewed in Wine Advocate # 170 on Apr-07


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Cheap electronic drum set are getting more popular thanks to its improving features that are closing the divide between electric and acoustic kits in terms of sound, tone, and feel. There was a time when e-drums were a weak attempt to copy the true drumming experience of an acoustic set. Today drum pads are getting more responsive than ever and the processed sound is very accurate that it is ...
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Hello, selling these for my friend who is unable to. He gave me this info.....drums are Tama 7 pc. Shell kit 8,10,12,14,16,22,14 snare. 700.00 cash firm. Reason for selling, a friend had a stroke. Drum set brand new. Never played.zero mark's. Also microphones included. Selling these at a loss.
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Talking PTAB with Bob Steinberg
Indefiniteness Before the PTAB
Collaborating Before The PTAB
Is The Deck Stacked Against Patent Owners In The PTAB?
Inter Partes Review: Validity Before the PTAB
Ropes & Gray: Advantages of the Patent Trial and Appeal Board
Post-Grant Insights: The Significance of a Three-Judge Panel
Post-Grant Insights: The Need for Seamless Coordination of District Court & PTAB Litigation
IP|Trend: Inter Partes Review: Is it Litigation or Something Else?
Post-Grant Insights: The Preparation and Pace of the PTAB
Post-Grant Insights: The Impact of PTAB Appeals on the Federal Circuit
Post-Grant Insights: Key Considerations in PTAB Oral Hearings
Post-Grant Insights: What claims to include in your PTAB petition
The Art of Communicating to a Jury
Precedential Impact of Patent Trial & Appeal Board Decisions in Post-Grant Proceedings
Patent Office Litigation Update: Stays
Patent Office Litigation Update: IPR/Supplemental Examination Interplay
Patent Office Litigation Update: IPR Discovery and Evidentiary PTAB Decisions
Patent Office Litigation Update: Patent Zombies
AIA Impact on Start Up Capital
Addressing issues related to introducing additional prior art references after institution of an inter partes review (IPR), the US Court of Appeals for the Federal Circuit affirmed a Patent Trial and Appeal Board (PTAB or...more
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In In re Magnum Tools International, Ltd., [2015-1300] (July 25, 2016) the Federal Circuit reversed the PTAB's determination that the challenged claims U.S. Patent No. 8,079,413 were invalid for obviousness.
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In SkyHawke Technologies, LLC v, Deca International Corp., [2016-1325, 2016,1326] (July 15, 2015), the Federal Circuit granted Deca's motion to dismiss SkyHawke's appeal of a PTAB Decision in a reexamination on the grounds...more
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Many factors must be considered for due diligence and valuation of a patent portfolio. The patent owner's desire to have broad claims that capture a large number of infringements must be tempered against its need for claims...more
The US Patent and Trademark Office (USPTO) announced a new pilot program for responding to final rejections. This program, called the Post-Prosecution Pilot Program (P3), combines the three-examiner panel of the Pre-Appeal...more
On July 11, 2016, the U.S. Patent and Trademark Office (USPTO) initiated the Post-Prosecution Pilot (P3) Program. Under the P3 Program, applicants can request a panel of examiners to participate in a conference with the...more
Many parties in front of the Patent Trial and Appeal Board (Board) struggle with the handling of evidentiary issues. This struggle is heightened when expert evidence is the focus. In Tietex International, Ltd. v. Precision...more
The Board has instituted IPR2016-00408 and IPR2016-00409 on AbbVie Biotechnology's U.S. Patent No. 8,889,135, which covers methods of treating rheumatoid arthritis with a human anti-tumor necrosis factor a antibody. This...more
Merck Sharp & Dohme Corp. has filed an IPR petition on U.S. Patent No. 6,331,415. This patent has been challenged several times over the past year with mixed results: IPR2015-01624 (instituted); IPR2016-00383 (not...more
Recently, the Supreme Court declined to make any changes to IPR procedure in its opinion in Cuozzo Speed Technologies, LLC v. Lee, 579 U.S. ___ (2016). Relying primarily on statutory language and concepts of agency rulemaking...more
The Federal Circuit's recent decision in Shaw Industries Group, Inc. v. Automated Creel Systems, Inc., has shed some light on the estoppel provisions in America Invents Act (AIA) post-grant proceedings. Like the estoppels in...more
Supreme Court: Status Quo in Cuozzo -
Why it matters: On June 20, 2016, the Supreme Court decided Cuozzo Speed Technologies v. Lee, where it rejected challenges to the Patent Trial and Appeal Board (PTAB) inter partes...more
We are pleased to share this Perspectives on the PTAB newsletter. Its content is directed toward providing information and analysis of the decisions made by the Patent Trial and Appeal Board. We hope that this newsletter...more
On May 10, 2016, the Patent Trial and Appeal Board (PTAB or Board) designated five post-grant trial decisions as precedential, bring the total number of precedential decisions in inter partes review (IPR) and covered business...more
The older among us have "unlearned" the prohibition of the word "or" in patent claims, and have reasoned that if "or" is acceptable, its cousin "and/or" is acceptable in patent claims as well. A few years ago, the USPTO...more
Applying its own precedent, the US Court of Appeals for the Federal Circuit confirmed that the burden remains on the patent owner to demonstrate the patentability of substitute claims over the art of record in an inter partes...more
Last month, we noted two recent Patent Trial and Appeal Board (PTAB) decisions that appeared to signal a more exacting standard for defining what patents may qualify as covered business method patents, focused on finding a...more
Addressing the standards for a motion to amend claims during an inter partes review (IPR) proceeding, the Patent Trial and Appeal Board (PTAB or Board) granted a motion to amend the claims in an IPR, but ultimately denied...more
In Cuozzo Speed Techs., LLC v. Lee,[i] the U.S. Supreme Court rejected the patent owner's challenge to the U.S. Patent and Trademark Office's implementation of the Leahy-Smith America Invents Act's new post grant proceedings....more
Post Grant Review ("PGR") is a Patent Trial and Appeal Board ("PTAB") proceeding established under 35 U.S.C. § 321 that permits the PTAB to review the patentability of claims in a patent based on any grounds under 35 U.S.C. §...more
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|01-22-2012 04:32 AM CET - Business, Economy, Finances, Banking & Insurance
e-con Systems Launches High Definition Camera Board for AM37x/DM37x Series of Processors
Press release from: e-con Systems Inc.
e-con Systems Inc., a leading embedded design services company specializing in development of advanced customized camera solutions and related services announces its second 5MP High definition (HD) camera solution based on OmniVision OV5640 HD CMOS Image sensor for AM37x/DM37x processors from Texas Instruments.
e-con Systems' new camera daughter card e-CAM52_35x has the e-CAM52_5640_MOD, a 5 Megapixel camera module based on OV5640 image sensor. The camera daughter card in turn directly plugs on to the Digital Video port(DVP) interface of the DM3730 processor available on the DM3730 EVM board from Texas instruments.
"OmniVision is pleased to see e-con Systems adopt the OV5640 SOC sensor for their imaging product offerings. The development and release of e-con Systems' e-CAM52_35x daughter card and e-CAM52_5640_MOD camera offers a turn-key, 5 mega-pixel imager ready for multi-segment applications.
The OV5640 SOC sensor uses advanced pixel technology offering a fully-featured yet Moreover, our OmniBSI™ technology differentiates itself from competing products by enabling best-in-class low-light sensitivity as well as an ultra compact camera module that is 8.5 x 8.5 mm with a z-height of less than 5 mm." said Robbert Emery, Senior Business Development Manager, OmniVision Technologies, Inc.
The 5MP camera module is specifically useful in OCR, Barcode readers, Digital Still Camera, document visualizers, camera for rugged handheld among others.
Along with the camera daughter card, e-con Systems also provides drivers for Windows CE 6.0, Linux and Android.
The OV5640 image sensor has an integrated ISP inside it. The sensor's automatic image control functions include automatic exposure control (AEC), automatic white balance (AWB), automatic band filter (ABF), 50/60Hz automatic luminance detection and automatic black level calibration (ABLC).The image sensor can stream 720p@30fps using DVP interface. e-con Systems also provides sample application that demonstrates the 720p30 streaming video and 5MP still capture along with the host of other sensor controls and features.
"The OV5640 uses the advanced pixel technology from OmniVision and e-con's customers will be benefited by the superior image quality with very low noise provided by this image sensor. " said Mr. Ashok Babu, President, e-con Systems
e-con Systems has been providing a bouquet of services to its customers on the camera integration.e-con Systems provides various camera modules ranging from 1.3MP to 5MP, camera module customization, device drivers, lens options, camera driver development & customization services.
Customers willing to evaluate the e-CAM52_5640_MOD can choose to buy the e-CAM52_35x and evaluate its features on the DM3730 EVM board from Texas Instruments with the associated driver and sample application package provided by e-con Systems. The evaluation kit will be available in e-con Systems' website from Feb 1st 2012 onwards. For more information, please visit www.e-consystems.com/5MP-HDCameraBoard-omap-am-dm37x.asp.
About e-CAM
e-CAM is e-con's reference design featuring a camera board interfaced to a processor on its high speed CMOS interface. Customers buy the e-CAM boards from e-con along with the schematics and integrate it to their custom design. e-con also provides drivers for WinCE, Linux & Android and sample applications. For processors that don't have the Camera ISP pipeline, e-con Systems provides the complete software stack for raw image sensors.
e-con also offers individually crafted custom designs for customers interested in cameramodules, other than the ones which are currently being offered as "off-the-shelf" solutions. For more information on this e-CAM,
visit: www.e-consystems.com/cameramodule.asp.
e-con Systems, acknowledged by Microsoft as a Windows Embedded Gold Partner, is an embedded product development services company focused on concept to product solutions with a strong technology leadership in camera solutions. e-con Systems has expertise in mobile application processors including PXA320, TI DM37x and Digital Media Processors DM355/DM365 and has been using its product engineering services to help customers on development of products based mainly on camera like video surveillance equipment, IP cameras, Low vision aid equipment, document visualizers.
e-con Systems, Inc
1516 Strawberry Glen Ct,
Ballwin, MO 63021, USA
Phone : +1-636-898-8788; +1 314 732 1152
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In the heart of San Francisco's Marina District, this convenient hotel has amenities and services within walking distance of Fisherman's Wharf, restaurants and shopping.
"Everything. Frendly personal, clean room, good location, afordable price, comfortable bed."
2,410 reviews
Less than a 2-minute walk from Union Square and the city's cable car services, Touchstone Hotel - City Center features free Wi-Fi and an on-site local deli.
"Great location, one block away from Union Square, …th great pressure. Staff extremely nice and kind."
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This eco-friendly San Francisco hotel features rooms furnished with coke bottle blankets and recycled furniture. It provides guests with free use of bicycles. Union Square is 1 mile from the hotel.
"Great location, decent neighborhood, and had parking."
2,243 reviews
This historic San Francisco hotel is along the Powell Street Cable Car line, one block from shopping at Union Square. It features contemporary rooms with free wired internet.
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Located in downtown San Francisco, in Union Square, this hotel is a 9-minute walk from Chinatown. A 24-hour front desk is offered and charming rooms provide cable TV.
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This hotel is in San Francisco's Theatre District, across from the Curran and ACT Theaters. Shopping at vibrant Union Square is just 2 minutes' walk away. A 24-hour front desk is offered.
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Conveniently located near San Francisco's fashionable Union Square, the Amsterdam Hostel places you in the center of the city and close to many of the area's major attractions.
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1,350 reviews
Across from the historic Muni tram station, this hotel offers access to major downtown San Francisco attractions. This hotel features comfortable accommodations in a central and convenient location.
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Charming Hayes Valley, in the heart of San Francisco, is home to this cozy inn, with easy access to attractions as well as local shopping, varied restaurants and public transportation.
"I loved the breakfast, fresh fruit, many types of …e number of channels available on the television."
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Serving a daily breakfast with bagels, fruit, coffee, and more, this San Francisco hostel is conveniently located within a 5-minute walk of Union Square. Each guest room includes free Wi-Fi.
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Ready in 45 minutes
I regularly make this dip and take to work to eat with fruit as a snack. It is soooo good.
1 people want to try | 3 have favorited
In medium bowl, combine cream cheese, marshmallow creme, and grated orange peel. Gradually stir in enough orange juice to make a mixture of dipping consistency. Cover, refrigerate at least 1 hour to blend flavors. Just before serving, cut cake into bite size cubes. Spoon dip into small serving bowl. Serve cake and fuit as dippers.
Kowgirl777 10y ago[I posted this recipe.]


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Vanberschot Family History & Genealogy
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- Christine P Vanberschot born 1950
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- Jeannette R Vanberschot born 1917
- Helen Vanberschot born 1907
- Mariepaul Vanberschot born 1892
- John Vanberschot born 1901
- Elsie A Vanberschot born 1909
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- Catherine N. (Vanberschot) Basic born 1983
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Jobs plan on the move: Petition asking White House to consider building Death Star exceeds 25,000 signatures
**Written by Doug Powers
Paul Krugman could write a whole book explaining why we should follow through with this petition:
Our favorite of these petitions this month has to be from Colorado man "John D" who, as we reported last week, wants the government to secure resources and funding to begin the construction of a Death Star by 2016.
His rationale for building the mega-weapon from the 'Star Wars' movies is as much public works project than direct threat to the little green men who could be living below Mars' surface.
"By focusing our defense resources into a space-superiority platform and weapon system such as a Death Star, the government can spur job creation in the fields of construction, engineering, space exploration, and more, and strengthen our national defense," he writes.
Petitions on the White House website require 25,000 signatures to be eligible for a response, and that number was exceeded today.
So, would building a "Death Star" type of thing be an affordable job creator?
According a recent study it would cost $852,000,000,000,000,000 — or 13,000 times the world's GDP — just to produce the steel required to build the weapon.
Putting on my "Obama economic advisor" hat for a moment, that would absolutely be doable. It would be simple: Calculate how much all those battles in Star Wars would cost to fight in real life and then budget for them by spreading the cost over a thousand years. Then, call off the wars and front load the "savings" to finance construction. This deal pays for itself! And if there still isn't enough to cover the cost, any remaining debt is probably nothing that couldn't be erased with one push of Ben Bernanke's QE5 button.
**Written by Doug Powers
Twitter @ThePowersThatBe
Clinton has a new greatest career accomplishment: Getting through that 'tough on Wall Street' talk without laughing
July 29, 2016 01:04 PM by Doug Powers
Hillary's acceptance speech: Woman in public eye for 25 years finally introducing herself to America
July 28, 2016 05:37 PM by Doug Powers
IRS investigating Clinton Foundation, and we all know how that's going to turn out
July 28, 2016 11:42 AM by Doug Powers
Interesting: The Clinton campaign seems to think Hillary's yoga-related emails are matters of nat'l security
July 27, 2016 07:00 PM by Doug Powers
#BlueLightFriday: From the White House to your house
July 27, 2016 07:25 AM by Michelle Malkin
Categories: Feature Story, Politics


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