text:
Hydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma
This study is ongoing, but not recruiting participants.
OHSU Knight Cancer Institute
National Cancer Institute (NCI)
Information provided by (Responsible Party):
OHSU Knight Cancer Institute
ClinicalTrials.gov Identifier:
First received: September 17, 2012
Last updated: December 2, 2015
Last verified: December 2015
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study is ongoing, but not recruiting participants.
|Estimated Study Completion Date:
|No date given
|Estimated Primary Completion Date:
|April 2016 (Final data collection date for primary outcome measure)


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Chitty Chitty Bang Bang Soundtrack, Original recording reissued
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The score by the brothers Sherman is wonderful. This is the only score they wrote for a non-Disney film. The score for MARY POPPINS was written by the same duo. This film was actually meant to star Julie Andrews as Truly Scrumptious, but Andrews already felt too typecast from previous films and declined the role. But Sally Ann Howes is perfectly cast here and gives a remarkable performance. Dick van Dyke, as always, is charming. Also loved the casting of the two children. They can really carry a tune.
Ironic trivia: Howes was a replacement for Julie Andrews in the stage version of My Fair Lady.
The ONLY reason I must hold back from giving 5 stars is that the sound quality on this disc, while not terrible, does not allow the music to shine as glorious as it should. There is quite a bit of tape hiss evident throughout, which is distracting, and it does bring down the sonic quality of the performances. Hopefully future releases of this soundtrack will have that problem rectified. But that doesn't mean you should pass this disc up and wait for the next release. It is still wonderful and the score will always remain a favorite of children and adults alike.
I took one star off, however, for the simple reason that these 16 tracks don't even add up to 40 minutes of audio, which is why the exclusion of the demos that are included on the 2-Disc DVD baffles me. I made myself a copy of the CD with both the songs from the CD and the demos from the DVD, and it came to just under 70 minutes. It'd be nice if in the future, a new soundtrack was released with the demos, or even just the full songs, including the instrumental breaks. It's about time these record companies started taking advantage of a CD's ability to hold up to 80 minutes of audio.
Despite any flaws, I wholeheartedly recommend this soundtrack to ANY fan of the film. It presents all of the classic songs in a satisfactory presentation, and is wonderfully nostalgic. The songs aren't as good as the songs you'll find in any great Disney classic, but they're still fantastic fun.
There are two prime numbers for Miss Howes to show her mettle ("Lovely Lonely Man" and "Doll on a Music Box"). Under-rated British musical star Anna Quayle, as the fearsome Baroness, has the cute "Chu-Chi Face" with Gert Frobe. Not just a children's musical!
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The Sherman Brothers at their best again. Thankfully they didn't force Dick van Dycke to try and use an English accent as in Mary Poppins.Published on July 7, 2014 by James Lyon
I love this movie and I was very happy to find the original movie music because I'm not too crazy about the broadway version. Read morePublished on December 11, 2013 by Gerisa Y. Thompson
My daughter loves it. One of her favorite movies. And with her favorite actor Dick Van Dyke, her older man crush at age 21.Published on October 5, 2013 by MAT-wdw2014
I enjoyed the movie, and could only find the Broadway CD version. So, I searched Amazon, and there it was it! I'm so very happy to have this in my collection.Published on December 4, 2012 by Antonette
I bought it for my grand daughter and she loves it. Shipment arrived within 5 days and in good condition.Published on May 27, 2010 by Joey
I must admit to being particularly uncritical about Chitty Chitty Bang Bang, as I imprinted on the film as a very, very young child. The same holds true for the soundtrack. Read morePublished on December 20, 2009 by David I. Salter
Because its a classic, I guess I'm old. But I know what I like in music.Published on February 12, 2008 by Christine Andersen
My 2 year old daughter loves the movie Chitty Chitty Bang Bang and asks to watch it all day long. I will often offer the soundtrack instead, and she will dance and sing along to... Read morePublished on March 20, 2007 by Mine
The music from the movie is great but the sound quality on the cd is no where near as good as it could be. Read morePublished on March 8, 2007 by Andrea Turner


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OF Darren Ford (Vineland) went 1-for-3 with a sacrifice fly and a stolen base for the Indianapolis Indians (Pirates) in a 10-3 loss to Gwinnett in the triple-A International League on Thursday. Ford is hitting .205 with 19 runs scored, 12 RBIs and 9 stolen bases in 53 games.
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In Reply: These correspondents share 2 concerns.
The first is disagreement with our selection criteria for articles1—that the criteria were excessively stringent
in restriction to human samples, peer review, masked assessment, and prospective
recruitment, and simultaneously inadequately selective with respect to attrition
and sample size. Animal studies are, as the thalidomide tragedy showed, unreliable
indicators of a teratogenicity of a substance or its safety in humans. Methodologic
issues also influence interpretation of animal data—whether cocaine
effects are found varies by species, sex, timing of exposure, mode of administration,
age at assessment, and whether control animals were pair fed with exposed
animals.2 Except for the article by Leech
et al,3 which was presented in detail in
our review, the other articles with human subjects cited by Drs Stanwood and
Levitt were in a non-peer–reviewed publication.4
Without the exposition of the methods demanded by a peer-reviewed journal,
these works-in-progress cannot be interpreted with confidence. We make no
apologies for excluding, in spite of large sample sizes, articles that lack
prospective recruitment or masked assessment; these criteria were justified
in detail in our review.1
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Now showing items 1-10 of 67
Correction to "Elastic wave speeds and moduli in polycrystalline ice Ih, sI methane hydrate, and sII methane-ethane hydrate"
(American Geophysical Union, 2009-04-10)
Duration and severity of Medieval drought in the Lake Tahoe Basin
(Elsevier B.V., 2001-09-16)
Droughts in the western U.S. in the past 200 years are small compared to several megadroughts that occurred during Medieval times. We reconstruct duration and magnitude of extreme droughts in the northern Sierra Nevada ...
NOAA/West Coast and Alaska Tsunami Warning Center response criteria
(Tsunami Society, 2009)
West Coast/Alaska Tsunami Warning Center (WCATWC) response criteria for earthquakes occurring in the Atlantic and Caribbean basins are presented. Initial warning center decisions are based on an earthquake's location, ...
Size distribution of submarine landslides and its implication to tsunami hazard in Puerto Rico
(American Geophysical Union, 2006-06-13)
We have established for the first time a size frequency distribution for carbonate submarine slope failures. Using detailed bathymetry along the northern edge of the carbonate platform north of Puerto Rico, we show that ...
Geomorphic and stratigraphic evidence for an unusual tsunami or storm a few centuries ago at Anegada, British Virgin Islands
(Springer, 2010-10-26)
Waters from the Atlantic Ocean washed southward across parts of Anegada, east-northeast of Puerto Rico, during a singular event a few centuries ago. The overwash, after crossing a fringing coral reef and 1.5 km of shallow ...
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To improve our understanding of the interaction of methane gas hydrate with host sediment, we studied: (1) the effects of gas hydrate and ice on acoustic velocity in different sediment types, (2) effect of different ...
Diversity and biogeochemical structuring of bacterial communities across the Porangahau ridge accretionary prism, New Zealand
Sediments from the Porangahau ridge, located off the northeastern coast of New Zealand, were studied to describe bacterial community structure in conjunction with differing biogeochemical regimes across the ridge. Low ...
More than a century of bathymetric observations and present-day shallow sediment characterization in Belfast Bay, Maine, USA: implications for pockmark field longevity
(Springer, 2011-02-07)
Mechanisms and timescales responsible for pockmark formation and maintenance remain uncertain, especially in areas lacking extensive thermogenic fluid deposits (e.g., previously glaciated estuaries). This study characterizes ...
Seismic imaging of deep low-velocity zone beneath the Dead Sea basin and transform fault : implications for strain localization and crustal rigidity
(American Geophysical Union, 2006-12-23)
New seismic observations from the Dead Sea basin (DSB), a large pull-apart basin along the Dead Sea transform (DST) plate boundary, show a low velocity zone extending to a depth of 18 km under the basin. The lower crust ...
Submarine landslide as the source for the October 11, 1918 Mona Passage tsunami : observations and modeling
(Elsevier B.V., 2008-05-17)
The October 11, 1918 ML 7.5 earthquake in the Mona Passage between Hispaniola and Puerto Rico generated a local tsunami that claimed approximately 100 lives along the western coast of Puerto Rico. The area affected by this ...


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- What other names is Coolwort known by?
- What is Coolwort?
- How does Coolwort work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Coolwort.
What other names is Coolwort known by?Foam Flower, Mitrewort, Tiarella cordifolia, Tiarelle Cordifoliée, Tiarelle Feuille-en-Cœur, Tiarelle à Feuilles Cordées.
What is Coolwort?Coolwort is an herb. It is used to make medicine.
People take coolwort tea for urinary tract problems including bladder stones and other bladder diseases; and for digestive disorders including indigestion and heartburn. Coolwort is also used for fluid retention and as a tonic.
Insufficient Evidence to Rate Effectiveness for...
- Urinary tract problems.
- Bladder diseases.
- Bladder stones.
- Digestive disorders.
- Indigestion.
- Heartburn.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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Engine Performance problem
2001 Hyundai Accent 4 cyl Two Wheel Drive Automatic 75000 miles
My radiator and head gasket have kicked the bucket. My mechanic has offered to repair them for $1700, which is a price a little to high for me. The mechanic has offered me $400 to buy the car and he would repair it for his daughter. This leads me to believe that I am about to be ripped off. Luckily My brother-in-law is a mechanic and might be able to do the repairs himself, the question though is it best to sell it or repair it?
Justin Schwab
Monday, December 1st, 2008 AT 12:23 PM


text:
Kevin DrumJan. 9, 2009 12:15 PM
LIGHTING A FIRE....Felix Salmon finds a silver lining to today's very, very grim employment report:
Maybe the only real upside to this report is that it should light a fire under Congress to pass a stimulus package sooner rather than later including the release of the second tranche of TARP funds. Let's start getting money out the door now: that's more important than haggling over what goes where.
Well, it worked for FDR. Maybe it will work for BHO too.
Jonathan SteinJan. 9, 2009 12:00 PM
Despite the fact that President-elect Obama described his stimulus package on Thursday with only broad generalities, the proposal is already coming under criticism from economists on the left. Anxiety that the package is too small is combined with a fear that the rumored $300 billion in tax cuts for individuals and corporations will do little to jump-start the economy. They argue that Obama, in seeking a solution that Republicans on the Hill will support, has sacrificed key components that would make the package work most effectively.
Paul Krugman, Nobel Laureate and in-house economic lefty for the New York Times, wrote on his blog this week:
[Read more]
David CornJan. 9, 2009 11:51 AM
With one hand, he giveth, with the other....
By tapping Leon Panetta to be CIA chief, President-elect Barack Obama sent a clear signal: no to torture. A year ago, Panetta wrote an article declaring, "We cannot and we must not use torture under any circumstances." And he included waterboarding--which the CIA has used---as torture. When Obama on Friday morning publicly announced his appointment of Panetta, he declared, "under my administration, the United States does not torture." He noted that he was handing this "clear charge" to Panetta and that this policy "will ultimately make us safer."
In fact, Obama's reported first choice for the CIA job, John Brennan, a career CIA official, had had his chances scuttled after bloggers and others griped that he had been soft, if not supportive, when it came to torture and CIA renditions. A New Yorker piece by Jane Mayer identified him as a "supporter" of so-called enhanced interrogation methods. And in a 2006 PBS interview, Brennan said, "we do have to take off the gloves in some areas" but without going so far as to "forever tarnish the image of the United States abroad." He added that the "dark side has its limits."
Well, Brennan didn't get the top post at Langley. But Obama has selected him to be his chief counterterrorism adviser in the White House. The job requires no Senate confirmation. So Brennan will not be inconvenienced by questions regarding any past involvement with CIA renditions and waterboarding. (Brennan has reportedly told Obama he had no direct role in CIA's abusive interrogation policies and even internally expressed reservations.) In announcing Brennan's appointment, Obama noted, "John has the experience, vision and integrity to advance America's security."
Kevin DrumJan. 9, 2009 1:56 AM
PAY NO ATTENTION TO THE PARTY BEHIND THE CURTAIN....Citigroup has agreed to drop its opposition to "cramdown" legislation:
Key congressional Democrats on Thursday reached an agreement with financial giant Citigroup Inc. on a proposal to make it easier for bankruptcy judges to adjust the terms of home loans and possibly forestall many foreclosures.
....The breakthrough agreement boosts the chances that Democrats can push new laws through Congress that direct bankruptcy judges to rework mortgage terms by writing down the principal on the millions of homes that now are worth less than the mortgages they carry.
Key congressional Democrats on Thursday reached an agreement with financial giant Citigroup Inc. on a proposal to make it easier for bankruptcy judges to adjust the terms of home loans and possibly forestall many foreclosures.
....The breakthrough agreement boosts the chances that Democrats can push new laws through Congress that direct bankruptcy judges to rework mortgage terms by writing down the principal on the millions of homes that now are worth less than the mortgages they carry.
Most of the reaction to this announcement has been dismay that Congress had to "negotiate" with Citigroup in order to pass this legislation, but it's important to get clear what's actually going on here. The negotiation wasn't really with Citigroup, it was with Senate Republicans, who have almost unanimously opposed this legislation in the past. With Citigroup on board, Durbin and Dodd and Schumer hope that other banks will hop on board too, and once the banks are on board then maybe a few of those legendary "moderate" Republicans will also see the light and do the right thing.
Maybe it will work, maybe it won't. But it's Republicans that are the problem. Banks are just fronting for them.
Bruce FalconerJan. 8, 2009 5:45 PM
Desperate times call for desperate measures. Nowhere is this more the case than with today's commercial aviation business, whose slow death has been accelerated of late by the twin nightmares of soaring fuel costs and global recession. The price of oil is way down from last year, but the financial breather will inevitably be short-lived as scarcity of fossil fuels grows in years to come.
What's a desperate airline to do? Charging for alcoholic beverages and checked bags won't cut it. (Don't expect these costs to vanish any time soon.) Nope, the only solution lies in experimentation with new fuel sources. Take Virgin Atlantic. Last year, Richard Branson's airline made news by powering a Boeing-747 with fuel partially derived from oils extracted from babassu nuts and coconuts.
In a piece I wrote for Mother Jones prior to the Virgin flight, I reported on widespread speculation that Branson might also choose to test algae as a biofuel. He never did so, of course, and now Continental Airlines has beaten him to the punch.
From the BBC:
The 90-minute flight by a Continental Boeing 737-800 went better than expected, a spokesperson said.
One of its engines was powered by a 50-50 blend of biofuel and normal aircraft fuel.
Wednesday's test is the latest in a series of demonstration flights by the aviation industry, which hopes to be using biofuels within five years.
The flight was the first by a US carrier to use an alternative fuel source, and the first in the world to use a twin-engine commercial aircraft (rather than a four-engine plane) to test a biofuel blend.
Party BenJan. 8, 2009 5:23 PM
We've been rather dry around the Riff lately (D.R.M.! TV News!) so I think it's time to get back to basics: New Tunes That Are Good. This week, a Swedish stomper, Texas tempos, a Slumdog standout, Bogota boogie, and, er, Scottish self-hatred.
1. Peter Bjorn & John - "Nothing to Worry About" (from Living Thing, out March 31)
Kanye could barely contain his enthusiasm, and neither can I. If you thought PB&J were only about shuffly, twee little ditties, get ready to have your mind blown by this stompy, shouty number. A bunch of kids scream the chorus while a wobbly guitar noodles over the beat from "Lip Gloss." What's not to like? (mp3)
2. Aether - "Orfeu Negro" (from Artifacts, out now on Exponential)
Aether is San Antonio producer (and graphic designer) Diego Chavez, and if you go look at some of his pretty pictures on his MySpace page whilst listening to this groovy number from his new album, you may notice some similarities: both his music and art are experimental but warm, detailed but instantly catchy, undeniably new but with a delicate retro patina.
Kevin DrumJan. 8, 2009 3:01 PM
CONYERS vs. GUPTA....Sam Stein reports that Rep. John Conyers has decided to publicly oppose the nomination of Sanjay Gupta as Surgeon General. That's.....weird. I don't really care much one way or the other about Gupta (though having a telegenic personality lead our public health service seems like a pretty inspired idea, frankly), and it's hard to believe that Gupta's smackdown with Michael Moore three years ago is anything more than a minor blip in the grand scheme of things. I wonder why Conyers is bothering to expend political capital on this?
Kevin DrumJan. 8, 2009 2:26 PM
QUOTE OF THE DAY....From Ezra Klein, explaining why Cass Sunstein's appointment as head of OIRA matters:
The key event here, and this gets a bit dull, was Executive Order 12291.
That does sound dull, doesn't it? But it's not, really, and Ezra provides a nickel summary of how the Office of Management and Budget has gotten so powerful over the past few decades and why its regulation watchdog is important. Go read.
Kevin DrumJan. 8, 2009 2:12 PM
GREEN REGULATIONS....Josh Marshall wonders what kind of coalition is likely to arise to support green infrastructure spending:
In the avalanche of writing about a massive Stimulus Bill, the one proposition (though grandly general) that's been of most interest to me is one that is heavy on infrastructure spending and spending and R&D geared toward developing a sustainable Green economy....But is there a constituency in Congress for that?....The key is that I don't think it really lines up in traditional left-right terms. For instance, it's not clear to me that the Progressive Caucus in the House is that constituency necessarily. I suspect it likely cuts across established factions among the Democrats, and likely brings in elements of the business community not surprisingly, the ones who'd get the contracts.
I don't know enough about this to say anything substantive, but I have the strong impression that a huge part of the answer to this is related to regulation. Right now, the energy industry is hemmed in by a vast web of state, local, regional, and federal regulation, and to get anything serious done you have to somehow either get all these various actors moving in the same direction or else cut completely through the mess via federal fiat. Which is much harder than it sounds. Even something relatively simple, like a carbon tax (simple from a policy perspective, anyway), has wildly varying consequences on different power generation plants depending on what kind of regulatory regime they operate under. Getting projects built and economic incentives right when they intersect with byzantine networks of regulation will turn you old and gray before your time.
This is something I should learn more about, but I haven't done it yet. In the meantime, I just wanted to mention it. In the real world, a lot of the solutions we'd like to see happen are going to be harder on a micro scale than a macro scale, and the coalitions that support them could end up looking pretty peculiar depending on what local regulatory changes are needed. On the upside, it's also a chance to bring in more supporters for green projects, since well-conceived regulatory changes could turn an erstwhile enemy into a newfound friend. More on this later.
Jonathan SteinJan. 8, 2009 2:12 PM
I'm joking, of course. The esteemed science mag runs an article in its January 2009 issue slamming John McCain and Sarah Palin, but with a serious purpose: pointing out that many of those oh-so-hilarious earmarks that the GOP ticket brought up as illustrations of congressional waste — "We spent $3 million to study the DNA of bears in Montana. I don't know if that was a criminal issue or a paternal issue," said John McCain, repeatedly — were actually examples of valuable scientific projects.
The DNA work on grizzlies that McCain mentioned was actually fairly standard stuff mandated by the Endangered Species Act. Scientists have to do DNA studies to track population fluctuations, which are important when an animal is, you know, endangered. The "overhead projector at a planetarium in Chicago, Illinois" that McCain mocked in a debate with Obama was, in reality, a replacement for the Adler Planetarium's star-projection system in its historic Sky Theater, the first planetarium theater in the Western Hemisphere. A statement from the planetarium after the debate said pointedly that the earmark request, which was not funded, was "not an overhead projector." And finally, the "fruit-fly research in Paris, France" that Sarah Palin dumped on during the campaign was actually $211,000 in funds that helped French researchers figure out ways to protect American crops from dangerous pests.
This is just the latest phase in the Republican war on science. We have some recommendations on how Obama can bring this long, stupid saga to a close.
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text:
3 Killed as Bus Catches Fire in Karnataka
At least 3 passengers were burnt alive after a private bus carrying 17 people caught fire in Karnataka's Hubballi city.July 27, 2016, 4:48 pm explore: India
"He Should Be Shot on Sight," Says Qandeel Baloch's Father About His Son
''She was my daughter and my best friend. She was like my son.''July 22, 2016, 2:31 pm explore: Buzz
26 Killed as Taiwan Tour Bus Bursts Into Flames
At least 26 people were killed after a tour bus burst into flames in Taiwan.July 19, 2016, 12:45 pm explore: World
Nitish Expresses Shock Over UP Hooch Tragedy, Pitches for Prohibition
Support of women is widely believed to have helped him win a third term in office despite having suffered a huge setback in the 2014 Lok Sabha polls.July 17, 2016, 9:58 pm explore: India
UP Spurious Liquor Tragedy Main Accused Arrested
Additional Superintendent of Police Visarjan Sigh Yadav said the number of persons taken ill was being investigated.Pranshu Mishra, July 17, 2016, 5:35 pm explore: India
Nice Truck Attack Undeniably of Terrorist Nature, Says Hollande
There's no denying the terrorist nature of this attack of yet again the most extreme form of violence: HollandeJuly 15, 2016, 1:07 pm explore: World
Islamic State Supporters Celebrate Deadly Attack in France on Social Media
The number of those killed had reached 62 french crusaders and sinful infidels in Nice: ISISJuly 15, 2016, 1:09 pm explore: World
Guns, Grenades Found Inside Nice Truck, No Hostages Taken: Officials
Anti-terrorism investigators have taken over the probe, prosecutors said.July 15, 2016, 1:16 pm explore: World
41 Accused in Kerala Temple Fire Tragedy Get Bail
The explosions had ripped chunks of concrete and plaster from the temple and nearby buildings which fell on people killing some on the spot and wounding many others.July 11, 2016, 4:11 pm explore: India
8 Dead in Fire at a Medical Store in Mumbai
Seven people have died after a medical store caught fire in Andheri West in Mumbai on Thursday.Radhika Ramaswamy, June 30, 2016, 9:46 am explore: India
A Rap Battle That Demands Justice For The Victims of the Bhopal Gas Tragedy
The rap battle breaks down the whole issue and pin-points every time the US Department of Justice has let this atrocity slideJune 2, 2016, 7:43 pm explore: Buzz
The Komagata Maru Tragedy of 1914 and a Hindi Film Based on It
'Jeevan Sangram' remains one of those forgotten but visionary films made in the '70s on India's independence movement.Bobby Sing, May 21, 2016, 10:42 am explore: Movies
Remember The Intro Theme of 'On Air With AIB'? Here's The Full SongMay 18, 2016, 2:17 pm explore: Buzz
Week After Kollam Tragedy, 2 Temples in Kerala Gets nod For Fireworks Show
The fireworks display at Thrissur Pooram got a go ahead from court on Thursday but with certain restrictions. The fireworks at Puttur's Mahalingeshwar Temple also got a no objection certificate with its fair share of riders.April 17, 2016, 10:44 pm explore: India
Thrissur Pooram Festival: Muted Show After Kollam Blast
After the Kollam temple tragedy all eyes are now on the Thrisurpooram festival which is expected to feature a more elaborate fireworks display. Authorities seem to be taking no chances and have deployed 2500 security personnel to avoid a repeat of last week's tragedy.Shylaja Varma, April 16, 2016, 9:49 am explore: India


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Houses to let in Teawell Close, The Rock, Telford TF3 - 5 bedrooms
Keywords and filters like garden and parking live here
Your search area is too large to further filter your results. Please edit your search location if you would like to filter your results.
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Property type
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£1,100 pcm (£254 pw)
Ralphs Close, Lawley Village TF4Property to rent - 5 bedrooms
Available from 1st Sep 2016
This outstanding five bedroomed house which is elegantly arranged over two floors offers spacious rooms, private wraparound garden, off-street parking with garage and features a superb location moments from Ironbridge (World Heritage Site) Junction 6 ...
Note: Distances are straight line measurements
- Telford Central (2.2 miles)
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Contact Us
Browse by:
Marliere; Philippe
Etiolles, FR
No. of patents:
Patent Number
Title Of Patent
Date Issued
Method for obtaining new life forms
June 14, 2011
The present invention relates to a method for generating a novel form of life comprising the steps consisting of: a) irreversible alteration of the genome of a microbial clone; b) cultivation of a vast population of microbial cells originating from the altered clone obtained in step a)
Cells and method for producing proteins comprising an unconventional amino acid
June 15, 2010
The present invention relates to a method for providing bacterial or yeast cells with the capacity to produce a protein, the amino acid sequence of which comprises at least one unconventional amino acid. The method involves (a) introducing at least one missense mutation in a target codon
Method for diversifying the chemical composition of proteins produced in vivo by genetically dis
April 28, 2009
The present invention is directed to a method to diversify the chemical composition of proteins produced in vivo comprising the step of disabling, particularly by mutagenesis, the editing function of one of its aminoacyl tRNA synthetases. The present invention is also directed to nuc
Stereoselective preparation of cyclic L-amino acids
September 16, 2008
The invention concerns a method for producing a cyclic L-amino acid of formula (I), characterised in that it consists in reacting a L-diamino acid of formula (II) or an enantiomeric mixture comprising such a L-diamino acid and a corresponding D-diamino acid in variable proportions, i
Lactobacillus N-deoxyribosyl transferases, corresponding nucleotide sequences and their uses
June 3, 2008
The invention concerns novel polypeptides and their fragments, isolated from Lactobacillus, having at least a N-deoxyribosyl transferase activity, the polynucleotides encoding said polypeptides, cloning and/or expression vectors including said polynucleotides, cells transformed by sa
Combinatorial production of nucleotide and nucleoside (XiTP) analogues
January 15, 2008
The invention concerns novel nucleotide analogues comprising a reactive hydrazide function used as initial synthons for preparing compounds (formula I) capable of inducing mutations or capable of inhibiting a DNA polymerase or a kinase. The invention also concerns nucleic acids compr
Enzymatic synthesis of deoxyribonucleosides
June 12, 2007
The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method.
Method and device for selecting accelerated proliferation of living cells in suspension
February 3, 2004
The present invention relates to a method and a device for selecting accelerated proliferation of living cells in suspension. The culture apparatus (2) of the present invention enables cells to proliferate in suspension over unlimited periods of time. Natural selection results in the
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Hey. Thanks for putting this plugin together. I'm really looking forward to using it on my website.
I'm wondering though, if you have any plans to implement a counter so people can see how many emails have been sent (e.g., "23 people" have participated in this action). That wold be awesome.
It might be a good idea to have a captcha of some kind as well, no? To stop the form(s) from being using for spam.
Thanks again for your work on this.


text:
Scarygirl (PC)
From GameWinners
Add to this page!
Steam achievements
Follow the indicated steps to earn the corresponding Steam achievement. To view your achievement progress and stats, open the Steam client, select "Community", then search for the game hub for "Scarygirl (PC)". Click the "View Stats" option in the drop down list, then select the option that displays the achievements for your account.
- Avalanche!: Survive Momma Yeti's cave-in.
- Chihoohoo's Test: Prove your worth to Chihoohoo in a rumble with his guards.
- City Enforcer: Force your way through Warmachine to get into Bad City.
- Dr. Maybee's Ultimatum: Make the tough choice when confronted by Dr. Maybee.
- Dreamer: Complete a Dojo training session.
- Heart of Gold: Collect a full heart container.
- Hoarder: Purchase all the shop items.
- Luminescent Danger: Triumph over the dangers deep beneath the sea.
- Novice Collector: Purchase a store item.
- Unleash the Guru: Start a Co-op game.
- Up Up and Away: Catch an Umbrella Seed to the Old Man Mountains.
- Winning: Achieve a perfect status on every level.


text:
|Publication number
|Publication type
|Application number
|Publication date
|Feb 24, 1987
|Filing date
|Jan 31, 1986
|Priority date
|Jan 31, 1986
|Fee status
|Also published as
|Publication number
|Arvid L. Erickson, Scott G. Erickson
|Original Assignee
|Erickson Arvid L, Erickson Scott G
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (21), Non-Patent Citations (1), Referenced by (9), Classifications (11), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
The invention relates to structural joints for connecting adjacent panels together. The structure joints have dowels, connectors and locking elements to secure meeting ends of adjacent edges of panels together.
Numerous joint structures and connectors have been used to join adjacent panels together. These structures include dowels, pins, clips, wood strips, and metal extrusions. Examples of structural joints for panels are disclosed by Williamson in U.S. Pat. No. 1,888,523; Barker in U.S. Pat. No. 3,323,819; and Logan in U.S. Pat. No. 4,438,578. Williamson discloses a structural joint comprising a generally L-shaped locking strip having bent longitudinal ends. The locking strip fits into linear grooves of adjacent panels to hold adjacent mitered edges of the panels together. Barker discloses a joinder 10 described as a symetrical L-bar located between bent end flanges of normally disposed panels. A pair of cylindrical wedges cooperate with the joinder to hold the panels in assembled relation with each other. Logan discloses right angle bracket adapted to fit into channels in adjacent beveled ends of a frame structure. The outer ends of the bracket have bent over portions that fit into cavities in the channels.
The invention is directed to an apparatus for securing adjacent edges of panels together in a manner which provides a sturdy and structural stable connection. The panels are provided with beveled edges with each panel having at least one normally extended groove. Connectors locked onto the adjacent edges of the panels holds the ends of the panels in a tight sealed relationship. The connectors are mounted on panels with a minimum of labor and time and without the use of special tools. The connectors form corners of a structure, such as a fixture, made up of a number of connected panels. The connectors have convex curved outer apexes and flanges that protect the corners of the structure and eliminate any sharp or abrupt edges.
The preferred form of the panel and connector assembly has a first panel with inner and outer surfaces extended into an end having a first beveled face. A groove is located normally to the beveled face adjacent the inner surface. A second panel having inner and outer surfaces and a second beveled face complimentary to the first beveled face of the first panel. The second panel has a groove extended normal to the second beveled face adjacent the inner surface thereof. A connector is used to join the first panel to the second panel. A connector has a generally flat web located between and in surface engagement with the first and second beveled faces. A lip joined to the web extends into the grooves. Flange means joined to the the outer edge of the web is engageable with the panels so that the lip and flange means hold the first and second faces in tight surface engagement with the web and fix the angular relationship between the first and second panels. Flange means extends at an angle relative to the lip to provide a hooked grip and tight sealed joint between adjacent ends of the panels.
In one form of the invention, the connector has a generally flat web provided with an inner edge and an outer edge. A flat lip is joined to the inner edge and extends normally in opposite outward directions from the web. A pair of flanges are joined to the outer edge of the web with a nose portion having a convex curved outer surface. The flanges are normally disposed relative to each other and have a length greater than the length of the lip. When the connector is in assembled relation with the panel, the flanges are in tight surface engagement with the outer surfaces of the panels and the beveled faces of the panels are located in tight surface engagement with the opposite flat sides of the web.
The panel and connector assembly of the invention is shown and described with use with a fixture for supporting merchandise. Other uses and advantages of the panel and connector are not precluded by this disclosure.
FIG. 1 is a perspective view of a fixture having the panels and connectors of the invention;
FIG. 2 is an enlarged sectional view taken along line 2--2 of FIG. 1;
FIG. 3 is an enlarged sectional view taken along line 3--3 of FIG. 1;
FIG. 4 is a sectional view of an end of a panel tapered and grooved to accommodate a connector;
FIG. 5 is a foreshortened perspective view of the connector of FIG. 3;
FIG. 6 is an enlarged sectional view taken along line 6--6 of FIG. 1; and
FIG. 7 is an enlarged sectional view taken along line 7--7 of FIG. 1; and
FIG. 8 is an enlarged sectional view taken along line 8--8 of FIG. 1.
Referring to FIG. 1, there is shown a fixture indicated generally at 10 for displaying and supporting merchanidise, cash registers, and the like in a retail or commercial environment. Fixture 10 supported on floor 11 has a plurality of horizontally grooved panels comprising a front panel 12, side panels 13 and 14 and a rear panel 20. Top section 16, 17, and 18 located at separate elevations are attached to the front side, and rear panels 12, 13, 14 and 20.
Referring to FIG. 2, front panel 12 has a inner continuous surface 19 and an outer surface 21. The outer surface 21 is interrupted with a plurality of vertically spaced horizontal T grooves 22. The cross portions or heads of the T grooves 22 are located along the center line 23 of panel 12. All of panels 12-14 have generally horizontal T grooves. The T grooves are preferably spaced three inches from center to center. The T grooves run the length of the panels. Alternate T groove spacing can be made on 2, 4, 6, and 8 inch centers. Panels 12-14 and top 16-18 may be made of wood, plastic, plastic and wood laminates and metal. The outer surfaces of the panels may be painted, unfinished, mirrored and/or wood veneered. The panels may have a fiberboard core and a veneer outer face. The panels can be used for wall displays, free standing fixtures, as shown in FIG. 1. A variety of brackets, hangers, and shelving (not shown) made of wood, metal or plastic are used with the panels to display merchandise. The supports have generally hook-shaped heads that fit into the T grooves to attach the supports to the panels.
As shown in FIGS. 1 and 3, a generally vertical connector indicated generally at 24 couple the adjacent ends of the panels 12 and 13. A connector indicated generally at 26 joins the opposite edge of panel 12 to side panel 14. A connector 27 joins side panel 14 to back panel 20.
Referring to FIG. 4, there is shown a cross section of an end of panel 12 shaped to accommodate connector 24. Panel 12 has a beveled or tapered end face 28 and a transverse outer corner 29. End face 28 has a 45 degree angle to form a right angle corner of fixture 10. The inner end of surface 28 is interrupted with a groove 31. Groove 31 projects normal to the plane of face 28 and is at an angle of 45 degrees with respect to the outer surface 21. Groove 31 forms with inner surface 19 and edge 32. The groove 31 has a generally rectangular cross section that extends the length of the end of panel 12. Groove 31 is formed with a circular saw or router bit. Other cutting tools and combination of tools can be used to cut groove 31 and face 28. The end face 28 and groove 31 can be simultaneously made with a combined plane and saw tool. The beveled face 41 and groove 42 is made in panel 13 in the same manner.
Referring to FIG. 5, there is shown connector 24 comprising a flat linear web 33 joined to a convex curved nose or apex 34. Web 33 has opposite flat surfaces that extend the length of connector 24. Outwardly directed flat flange 36 and 37 are joined to opposite sides of nose 34. The flanges 36 and 37 are normally disposed relative to each other. Web 33 bisects the angle between flanges 36 and 37. The inner end of web 33 is joined to lips 38 and 39. The lips 38, 39 extend in opposite directions from web 33 and are noramlly disposed relative to web 33. Lips 38 and 39 are shorter than the flanges 36 and 37 and are disposed at an angle of 45 degrees relative to the longitudinal planes of flanges 36 and 37. Connector 24 can be a metal extrusion, plastic, wood and like structural material. An example of connector 24 is a metal extrusion having a flat web with a transverse dimension of the faces on the ends of the panels. The lip 39 has a transverse dimension of 1.27 cm and projects normally from opposite sides of web 33. The flanges 36 and 37 each have a length of 1.90 cm and are located at right angles relative to each other.
Referring to FIG. 3, connector 24 is located in assembled relation with the adjacent ends of panels 12 and 13 to retain the panels in fixed relation relative to each other. Panel 13 has a flat angularly inclined end surface 41 and a groove 42 at the inner end thereof. The groove 42 forms a transverse edge 43 on the inside of panel 13. Edge 32 of panel 12 and edge 43 of panel 13 face each other to form the inside corner of the fixture. Web 33 is located in tight surface engagement with end surfaces 28 and 41. Flange 36 is located in surface engagement with the outside of the panel 13. Flange 37 is located in surface engagement with the outside of panel 12. The outer corners 29 and 40 of panels 12 and 13 are transversely cut off to prevent jaming of material in the inside corners of connector 24. This ensures tight surface engagement of faces 28 and 41 against web 33. Lips 38 and 39 are located in grooves 42 and 31 respectively. Lips 48 and 39 being located at an angle relative to the length of panels 12 and 13 hold or locks the panels in assembled relation with connector 24. Lip 38 holds surface 41 and outside surface of panel 13 in tight surface engagement with web 33 and flange 36. Lip 39 holds the end surface 28 of panel 12 and outer surface of panel 12 in tight surface engagement with web 33 and flange 37. Lip 38 extending across the inside corner of panels 12 and 13, the flat tight surface engagement of the ends of the panels with web 33, and the surface engagement of flanges 36 and 37 with the outside of panels 13 and 12 provide a hooked grip and tight sealed joint between adjacent ends of panels 12 and 13. Flanges 36 and 37 with convex nose 34 protects the outer surfaces of panels 12 and 13 located adjacent the joint. Special tools are not required to assembly connector 24 on adjacent panels 12 and 13. Additional parts and adhesives are not used to provide a tight structurally stable joint securing adjacent ends of panels together.
Referring to FIG. 6, there is shown connector 27 joining panel 12 to panel 14. Panel 12 has a flat beveled end face 44 and a groove 46 in the inner end thereof. Groove 46 is normal to end face 44. Groove 46 forms with the inner surface of panel 12 an inner edge 47. Panel 14 has a beveled or angled flat end face 48 having a groove 49 at the inner end thereof. Groove 49 is aligned with groove 46. Groove 49 forms with the inner surface of panel 14 and edge 51. Edges 47 and 51 are adjacent each other to form the inside corner of joined panels 12 and 14. Connector 26 has a flat web 52 located in surface engagement with the flat end faces 44 and 48. A web 52 extends the full length and width or transverse dimension of faces 44 and 48 and is joined to an outer convex curved flanges or head 53. The head 53 extends over the outside surfaces of panels 12 and 13 and has outer edges 57 and 58 that engage panels 12 and 14. The inner end of web 52 is joined to lips 54 and 56 extended into grooves 46 and 49. Lips 54 and 56 in conjunction with head 53 provide a hooked grip on panels 12 and 14 which holds web 52 in tight surface engagement with end faces 44 and 48 of panels 12 and 14.
Referring to FIG. 7, there is shown connector 27 holding panel 14 in assembled relation with back panel 20. Panels 14 and 20 are at an acute angle relative to each other. Panel 14 has a beveled or angled end face 59 and a groove 61 at the inner end thereof. Groove 61 is normal relative to end face 59. The inner surface of panel 14 has an edge 62 adjacent groove 61. Panel 20 has a beveled angled end face 63 and a groove 64 aligned with groove 61. The inside surface of panel 20 has an edge 66 at the outer end of groove 64. Edges 62 and 66 face each other when panels 14 and 20 are assembled together with connector 27.
Connector 27 has a flat web 67 that extends the length and width or transverse dimension end faces 59 and 63. The outer end of web 67 is joined to a convex curved nose 68. A pair of flat flanges 69 and 71 are joined to opposite sides of nose 61. Flanges 69 and 71 are located in surface engagement with the outside faces of the panels 14 and 20. Flanges 69 and 71 are angularly disposed relative to each other at the acute angle of the corner formed by panels 14 and 20.
Referring to FIG. 8, there is shown the connector indicated generally at 84 for joining top 16 to side panel 13. Side panel 13 has top edge faces 74 and 76 and a pair of grooves 77 and 78. Groove 78 extends in a transverse direction relative to the length of panel 13. Groove 77 is normal to the edge face 76.
Top 16 has end faces 79 and 81 and a pair of grooves 82 and 83. Groove 83 is normal to the length of top 16. Groove 82 is normal to the end face 81. Grooves 77 and 82 are located adjacent the inside surfaces of panel 13 and top 16.
Connector 84 has a generally flat web 86 that extends linearly along the length of top 16. The web 86 has opposite flat faces located in surface engagement with end face 76, panel 13 and the edge face 81 of top 16. End faces 74 and 79 are retained in firm surface engagement with each other by connector 84. Web 86 is joined to a pair of flanges 87 and 88 that extend into grooves 78 and 83. Flanges 78 and 88 are normal relative to each other and have obtuse angles relative to the plane of web 86. The inner end of web 86 has a pair of lips 89 and 91 extended into grooves 77 and 82. Lips 89 and 91 are normally disposed relative to the plane of web 86.
The top edge of side panel 13 is formed with the planar which steps faces 74 and 76. Cutting tools, such as a saw or router bits are used to form grooves 77 and 78. The end faces 79 and 81 in top 16 as well as the grooves 82 and 83 are formed in a similar manner. The top 16 is held in normal relation relative to side panel 13 with end faces 74 and 79 in engagement with each other. Connector 84 is linearly moved into the grooves 78, 83, 82, and 77. The entire length of top 16, 17 and 18 can be connected to their adjacent panels with a connector similar to connector 84.
While there has been shown and described preferred embodiments of the connectors for fabricating the fixture 10, it is understood that changes in materials, and modifications of the panels and connector structures can be made by those skilled in the art without departing from the invention. The invention is defined in the following claims.
|Cited Patent
|Filing date
|Publication date
|Nov 18, 1879
|Apr 13, 1880
|Dec 18, 1880
|Feb 22, 1881
|William h
|Feb 6, 1900
|Jan 14, 1902
|Espine Achard Et Cie Soc D
|System of jointing for joining up boxes, &c.
|Jul 16, 1907
|Oct 22, 1907
|Buel S Burroughs
|Splice and joint.
|Mar 24, 1914
|Jan 26, 1915
|Somerset Door And Column Company
|Wooden column.
|Jun 18, 1923
|May 12, 1925
|Jensen Carl C
|Fastening device
|Jun 8, 1929
|Nov 22, 1932
|Edward B Williamson
|Structural joint
|May 1, 1939
|Oct 29, 1940
|Mastic Asphalt Corp
|Building corner
|Mar 4, 1940
|Jul 15, 1941
|Mastic Asphalt Corp
|Building corner and method of making the same
|Apr 18, 1945
|Apr 16, 1946
|Gustave J Soderberg
|Jun 14, 1962
|Aug 17, 1965
|Preway Inc
|Frame corner fastener assembly
|Dec 12, 1961
|May 31, 1966
|Reynolds Metals Co
|Frame constructions and parts and methods for making the same or the like
|Dec 17, 1964
|Jun 6, 1967
|Clarence Barker Leslie
|Structural joints
|Aug 31, 1965
|Oct 10, 1967
|Lambert Frame And Picture Comp
|Clamps for picture frames
|Jun 7, 1967
|Sep 16, 1969
|Schlegel Mfg Co
|Garnishing bead miter joint and method of making same
|Jul 1, 1975
|Jun 28, 1977
|Derek Thomas Martin
|Constructional elements
|Feb 17, 1976
|Sep 27, 1977
|Renato Lucchetti
|Frame particularly for stretching a piece of painting canvas
|May 14, 1979
|Apr 14, 1981
|Scott Steve M
|Apparatus for holding boards in the making of furniture
|Sep 5, 1979
|Sep 22, 1981
|Indiana Wood Specialty, Inc.
|Table and method of assembly
|Apr 21, 1983
|Mar 27, 1984
|Logan Graphic Products, Inc.
|Picture frame and corner bracket assembly
|Title not available
|Citing Patent
|Filing date
|Publication date
|Sep 14, 1990
|Sep 1, 1992
|Bill Branham Designs, Ltd.
|Wall mounting system
|Feb 12, 1993
|Mar 21, 1995
|Erickson; Arvid L.
|Panel and connector assembly
|Nov 22, 1995
|Oct 14, 1997
|Apa-The Engineered Wood Association
|Corner angle connector
|Dec 28, 2001
|May 18, 2004
|Dalles C. Notermann
|Connected frame structure and method of connecting frame members
|Aug 1, 2006
|May 11, 2010
|Overmyer Jr Douglas
|Special cement-like coated mobile building and process to manufacture
|Apr 29, 2010
|Feb 24, 2015
|Rockwool International A/S
|Building assembly with a corner profile for an insulating building system
|Aug 1, 2006
|Nov 22, 2007
|Douglas Overmyer
|Special cement-like coated mobile building and process to manufacture
|Apr 29, 2010
|May 3, 2012
|Rockwool International A/S
|Building assembly with a corner profile for an insulating building system
|Oct 28, 1993
|May 11, 1994
|Chene Vert
|Assembly device for making recess fittings, and recess fittings thereby obtained
|U.S. Classification
|403/402, 403/403, 52/282.3
|International Classification
|Cooperative Classification
|European Classification
|Jun 4, 1990
|Fee payment
Year of fee payment: 4
|Mar 4, 1994
|Fee payment
Year of fee payment: 8
|Sep 15, 1998
|Maintenance fee reminder mailed
|Feb 22, 1999
|Surcharge for late payment
|Feb 22, 1999
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