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Get rid of ants & other insects with the Insecticides at home or work. These can be used in several locations simultaneously, no monitoring needed.
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There are a lot of harmful ailments in existence that lots of men and women merely don't know about. Despite the fact that you can find a lot of health conditions that might be fatal, most of them are usually treated if they may be resolved in time. The Legionnaires disease is undoubtedly amongst the few illnesses which is having an effect on tens of thousands of folks annually. The following will certainly examine even more about the history of Legionniares' disease, how it's typically caused along with just what someone ought to do if and when they end up attacked by it.
This type of disease was first discovered just about 40 years ago inside some type of hotel in the town of Philadelphia. Seemingly several people whom were participating in some kind of convention grew to be incredibly ill soon after. Doctors along with experts would continue on to figure out the folks were getting extremely ill due to an individual microbe that they ended up being subjected to. Sad to say, those individuals who ended up confronted with the bacterium for the duration of that time perished before an explanation could possibly be determined. You can visit www.healthnewsdigest.com if you're enthusiastic about finding out much more about the historical past of this horrendous ailment.
Once this illness was first identified, many people wondered exactly how it was introduced. Investigators discovered that the actual microbe leading to the exact sickness at the convention originated in the hotel's water system. Considering that the system wasn't thoroughly treated the bacteria were able to thrive and grow. After the air evaporated the bacteria were able to spread through the air. People can check out HealthNewsDigest.com so as to discover a little more about this also.
Immediately after hearing this specific report, a number of folks start to truly freak out and care about their own individual security and physical health. The fact is that, you have a fantastic reason to be concerned. There are many of firms of which don't properly sanitize their particular systems and this very same bacteria is allowed to cross cooling towers and AC units. When someone gets infected, they ought to seek out medical care as quickly as possible. Fortunately, this is often a sickness which will be able to now be handled.
If perhaps you'd want to find out far more information and facts with regards to this specific illness, take into account checking out Legionellosis: The Infectious Story of Pontiac Fever and Leg. Once more, this is really a condition that's over forty years old. Despite the fact that it can cause your demise you will find ways it may be dealt with.


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Contain preparedness information for different types of disasters, an interactive checklist for emergency kits, a section to plan emergency meeting locations, information on how to stay safe and recover after a disaster
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U.S. FEMA investigating voice mail hole that allowed hacker to make hundreds of calls overseas.
Sonia Arrison of the Pacific Research Institute frets about the prospect of a government-controlled Internet.
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FEMA needs reality check, Mississippi congressmen say: How can storm victims file for aid online when some still don't have electricity?
Computer Sciences, a computer services company specializing in outsourcing, consulting and systems integration, has been awarded a contract by the Federal Emergency Management Agency (FEMA) to continue supporting the federal government's National Flood Insurance Program (NFIP). The three-year contract has a base-period value of $35 million and could be valued at $61 million if all options are exercised over an additional two-year period. As the NFIP's Bureau and Statistical Agent, CSC will serve as the liaison between the government and more than 90 independent property and casualty insurance companies that issue federally guaranteed NFIP policies.


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Danfords Hotel and Marina, Long Island
- Free WiFi
Main amenities
- 86 smoke-free guestrooms
- Marina
- Near the beach
- Restaurant and bar/lounge
- 24-hour fitness center
- Self parking
- Massage/treatment rooms
- 24-hour business center
- 24-hour front desk
- Coffee/tea in a common area
- Air conditioning
- Daily housekeeping
What's around
- Heart of Port Jefferson
- Harborfront Park (0.1 mi / 0.1 km)
- Maritime Explorium (0.1 mi / 0.1 km)
- Port Jefferson (0.1 mi / 0.2 km)
- Theatre Three (0.3 mi / 0.5 km)
- Mather House Museum (0.3 mi / 0.5 km)
Danfords Hotel and Marina, Long Island
Hotel Info: 866-539-8117from $229
- Standard Room, 1 King Bed
- Standard Double Room, 2 Double Beds
- Standard Village View
Also popular with travelers from the USA
At a glance
Key facts
Hotel size
- This hotel has 86 rooms
- This hotel is arranged over 3 floors
- Check-in time starts at 4 PM
- Check-out time is 11 AM
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Pets not allowed
Extra people
- Roll-away beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- Self parking *
Other information
- Smoke-free property
Nearby Three Star Long Island hotels
In the hotel
- Restaurant
- Bar/lounge
- Coffee/tea in a common area
- 24-hour fitness facilities
- Spa treatment room(s)
- Marina on site
- 24-hour business center
- Number of meeting rooms - 8
- Conference space
- Meeting rooms 8
- Conference space size (feet) - 12000
- Conference space size (meters) - 1115
- 24-hour front desk
- Dry cleaning/laundry service
- Wedding services
- Number of buildings/towers - 8
- Safe-deposit box at front desk
- Television in common areas
- In-room accessibility
In the room
- In-room climate control (air conditioning)
- Air conditioning
- Coffee/tea maker
- Iron/ironing board
- Blackout drapes/curtains
- Premium bedding
- Private bathroom
- Shower only
- Free toiletries
- Hair dryer
- 32-inch flat-screen TV
- Premium TV channels
- Desk
- Free WiFi
- Daily housekeeping
- Connecting/adjoining rooms available
Top Long Island hotels
Recently reviewed hotels in Long Island
- Courtyard by Marriott NorwalkFrom
"Great place friendly staff we were there for only one night but would definitely stay there again"Jul 25, 2016
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"It's ok. Room was pretty good. Staff is really nice "Jul 23, 2016
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"I enjoyed having a kitchen since I was there a week but could also go right down to breakfast buffet for my morning coffee or food. The grounds were very attractive with nice…"Jul 23, 2016
- Best Western Plus Fairfield HotelFrom
"Comfortable hotel that would take us with our dog. Small rooms but comfortable and fully equipped. "Jul 22, 2016
Nearby hotels
Special features
DiningWave Seafood Kitchen - This restaurant serves breakfast, lunch, and dinner.
On Site
- Marina on site
- Personal motorized watercraft on site
- Ecotours nearby
- Golf lessons available nearby
- Golfing nearby
- Hiking/biking trails nearby
- Kayaking nearby
- Mountain biking nearby
- Sailing nearby
- Skydiving nearby
- Water skiing nearby
- Windsurfing nearby
Danfords Hotel and Marina, Long Island's small print
Also known as
- Danfords
- Danfords Hotel
- Danfords Hotel Port Jefferson
- Danfords Port Jefferson
- Danfords Hotel And Marina
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Optional extras
Self parking costs USD 8.00 per night
Microwaves are available for USD 10 per night
Refrigerators are available for USD 10 per night
Rollaway beds are available for an additional charge
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.
Recent reviews
Good 3.9 /5 from 147 reviews
Very nice hotel for overnight stay - busy hotel for group celebrations
Very hard to get to room with luggage. No elevators. Small low ceiling room. Terrible lighting in room. Uncomfortable beds. Hotel is outdated and needs updating.
This is one of the best stays for the money. I will check here first to see what the availability is next time I work in the area. I look forward to another stay.
We were there overnight attending stonybrook graduation
Me and my friends don't have a car so a lot of the amenities we couldn't do because it wasn't walking distance. Also, the town has peak seasons and we came off peak. Overall because I was with fun people and the room was very nice I had fun! But to truly enjoy the amenities you NEED a car. Overall it was a good stay.
Is the description of this hotel not correct? Tell us


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Andy Smith
Seasoned UNIX, Security and Network engineer. I'm here to answer questions I can help with, and to learn new things in the process.
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9 Parks near Gypsum, Colorado
Wolcott, Colorado 15.3 miles NE
Basalt, Colorado 17.92 miles S
Carbondale, Colorado 19.53 miles SW
Basalt, Colorado (map) | (970) 927-3405
Sites: 81 | Latest Rate: $43.00 | 13 Reviews
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Aug 2015 - $43.00
I'll preface this by saying I usually don't reserve a site in a park that doesn't have current reviews, but we wanted to be near Aspen/Snowmass Village and this CG in Basalt is the closest park with full hook-ups that can accommodate a motorhome. It is a small, older CG with narrow, tight, close gravel sites. We were in a pull-thru next to a few other motorhomes that were so close there was barely room to park the toad between. Water, electricity and cable worked fine. For us, this was just a place to park our RV while we spent time in a really beautiful area of CO. This park served our purpose. - jacksup1212
Sep 2013 - $45.00
If you go by first impressions you might just turn around and head to the nearest Walmart parking lot when you see this place. But in this case, first impressions do deceive. When you approach this park it looks like a decommissioned KOA with a bunch of old trailers and motor homes parked in it. There are a fair number of seasonal/permanent campers here, but the ones we met seem nice. The sites are level gravel, there are many pull-throughs, and all services work fine. Some of the sites are a bit narrow, but not so narrow they hamper awnings and slides. The cable TV is all digital with many channels to choose from. The WiFi is decent. The restrooms and showers are modern, spacious and spotless. The pool, which was closed for the season, looked nice. There's a short walk to the Eagle River which runs behind the park, and the park is situated about 12 miles from Aspen. The rate I quoted does not include the available AAA, AARP and Good Sam discounts. Yes, the grounds could use a bit of modernization, but all-in-all this is a very nice RV park. - DrLewie
Aug 2013 - $42.00
Not sure how to write this review. This place is the only game in town so if you're visiting Aspen it's pretty much where you stay. The folks running the place are very friendly and over all if you just need a place to sleep it's fine. We were here several nights. The grounds are right on the road and so there is road noise but it's white noise for the most part. The sites are very close together and by in large look to be either seasonal or year round homes. While generally quiet we did have a yippy dog next door but he only bothered us one night while his owner was out. It works, but it's not what we'd call pleasant. - ed & marti
1308 County Road 129 Glenwood Springs, Colorado 81601 (map) | (970) 945-6737
Sites: 113 | Latest Rate: $70.00 | 79 Reviews
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Jul 2016 - $70.00
"RESORT" it is not!! RV sites are extremely close together including slides close to cabin doors. Sites are gravel with very little maintenance. Office manager and staff were rude! We arrived earlier than the 2:00 check in time and were told we had to leave and come back on or after 2:00 pm so their maintenance people could prepare the site for us. During our 3 day stay, there was no maintenance preformed on any rv sites! We were also charged $5 per day for each dog although no dog area was provided! We booked online and were told that sites were not assigned until arrival, which was not the truth. Extremely expensive for what the so called "Resort" provided. - NvRver
Jun 2016 - $63.00
I can concur with most of the reviews about the poor location of the hookups, so be sure to plan accordingly. The location and outdoor offerings are fantastic so perhaps that's the reason for the high price. There was no cable at our site - 108 - but I didn't really mind. The temperature was ideal at 72 degrees and we didn't use our air conditioner. The laundry only has two apartment style stacked washer and dryer units which needs to increase due to all of the outdoor activities. Bring loads of quarters as these appliances are expensive. This location was a treat because of the canyon and river scenery but I am not convinced it was worth the admission fee. Also, we were travelling in a 25 ft. rig. - KC8RXQ
Apr 2016 - $63.00
The good and the bad...This park could be a rated as excellent, but because of some design flaws is just average. We pulled in with our MH and were surprised to be told immediately that our money was nonrefundable as soon as we signed the reservation paperwork. I thought that was strange, but when we drove to our site, it became all too apparent. The sites are somewhat narrow, not at all level, and not well laid out. Every site I looked at had the electric at the very back of the site, the water in the middle, and the sewer was in the front of the site. If you don't have 30 foot of sewer hose, you can wait until you leave, like we did, and dump by pulling forward out of the site, until your hose can reach. You will also need some boards to get your coach somewhat level. Not wanting my front wheels off the ground kept us walking uphill to the rear of our coach while we were here. Other than those things, the campground is in a great location, is quiet, and the scenery is spectacular. The staff was very helpful and courteous, and even changed their minds about not letting us stay here with our German Shepherd, although they charged us and additional $5 for the Shepherd and $5 for a 5 lb. Papillion. I definitely thought the price was out of line with the facilities available. Hopefully, the owners will reconsider the layout of the sites and improve upon their usability. We will probably drive right past this place on our return trip. - WhiskeyMan
Carbondale, Colorado (map) | (970) 963-2341
Sites: 36 | Latest Rate: $47.00 | 21 Reviews
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|Clean Showers:
Jul 2016 - $47.00
We had a beautiful back-in patio site next to the river. This is a campsite you can actually "hang out" at. We spent hours sitting by the river while the kids played. Sites are gravel and may require some leveling. Laundry machines are new. The store has ice cream and toys like bubble wands. There are no sewer hookups (park is right on the river); there is "honey wagon" service for stays of more than 3 days only. - Rpodder2
Sep 2015 - $45.00
The setting is drop-dead gorgeous. The location is close to day trips to Glenwood Springs, Marble and Aspen. It used to be the BRB and has been completely remodeled to KOA standards. There are nice cabins for couples and families and tent sites in addition to sites with hookups. The owner takes pride in the place and made us feel like we were part of her family. Her two boys even got into the act by delivering wood for our fire. We hope to plan a family reunion next year at this campground. - Bart1979
Sep 2015 - $45.00
Wonderful park we plan to put on our list as a "must stay" when we travel through the area. - Chris C
Gypsum, Colorado (map) | (720) 933-9212
Sites: 42 | Latest Rate: $40.00 | 36 Reviews
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Jun 2016 - $40.00
This is a good stop on I-70. It's a well kept rustic park along a rushing stream. I gave the service a 2 because there was no management on site although he was accessible by phone. Wifi was good. No reservations were accepted, just first come first served. I'd stay here again. - RVerMJ
Apr 2016 - $40.00
This place has potential. It is in a beautiful setting. There is a wonderful deck off the back of the office. The grounds are nicely laid out. Trees have been planted. Restrooms & showers are nice & individual rooms. No sewer hookup at sites but the dump station is easy access. The sites are far from level. I'm not sure why they are adamant about using pads under levelers since this asphalt is not worth saving. The grounds map shows a river front lounge area but we did not check this out. There are not many RV park options in this area. This is an option with easy access from I-70. - 2togoNebraska
Sep 2015 - $38.00
Rather rundown campground sandwiched between I-70 with its attendant truck noise and the Eagle river. Reasonable asphalt access roads. Sites are badly worn with uneven asphalt and minimal landscaping. Oddly jack pads are required. Sites were mostly level with picnic table and fire ring. Power OK (but no A/C loading), did not use water (but we were warned about fluctuating water pressure), no sewer. WiFi is rather pitiful - poor signal strength and long page loads (sometimes several minutes). Verizon is no real alternative - one or 2 bars mostly 3G with occasional LTE connection and very slow speed. No issue with satellite access. We would consider staying here again for an overnight, but no more. - SeaLandSkyPhoto
Glenwood Springs, Colorado (map) | (970) 945-5340
Sites: 44 | Latest Rate: $35.00 | 42 Reviews
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Apr 2016 - $35.00
The friendly and conscientious host (owner?) is very welcoming and provides area information as well as escort to your site. Interior roads are steep, rough and pot-holed. Sites are narrow, gravel, level terraced areas cut into the hillside. Mature trees provide shade at many sites. Many units appear to be old and permanent. Electric worked well, water pressure was low but okay, wi-fi was good, AT&T phone and data signals were fairly good in the area. Though we managed to enter and exit without mishap in our 39' fifth wheel the park is iffy for big rigs. - never settled
Apr 2016 - $35.00
Park is in a beautifully setting. the tiered sites provide everyone with great views.
However it definitely needs some work. The roads with in the campground are rutted & full of potholes, sites need to be leveled & could be wider.
Site services were easily reached and in good working order. Did not use any on the facilities such as laundry, showers, etc. - Our-Wandering-Casa
Jul 2015 - $35.00
The park could certain use some sprucing up. No place hardly at all to walk pets and the park is VERY steep throughout. Many sites are at very steep angles and obviously an older park, but will accommodate larger rigs. The driveway in is also very steep. That said, probably best bang for the buck in the area, especially for short term. - 7 on the road
Wolcott, Colorado (map) | (970) 947-2800
Sites: 6 | Latest Rate: $5.00 | 2 Reviews
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|Clean Showers:
May 2012 - $5.00
This is your basic, six-site campground. Not too clean, but serviceable. Sites are a tight go, even for a 32 foot Class A. Virtually no maintenance, but the pit toilet area was clean. Lots of boaters and fisherman frequent the area. Near the Interstate and Highway 6, so expect lots of traffic noise. Location is beautiful, near the Eagle River. - Red Wolf Deux
Sep 2009 - $10.00
Easy access from I-70. No facilities, three spaces will fit a 40' RV. Right on a trout stream. Fire rings, picnic tables and grills. Some highway noise, but not much at night. 50% off for senior access pass. Near Edwards, Colorado that has a dump station and fresh water right near the exit. Site #6 is the most level for a big rig and at the end of the campground. If there is someone occupying the end spot a big rig could not turn around, and would have to back out. There is an unattended money drop at the campground. - steved44
Eagle, Colorado (map) | (970) 328-2021
Sites: 56 | Latest Rate: $18.00 | 2 Reviews
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Sep 2015 - $18.00
Sylvan Lake State Park is real gem. The campground is very spacious, with several large pull-through sites and many sites that have a bit of a view of the lake. There are two sections, 34 sites well-spaced in a typical campground layout and 12 sites (Fisherman's Paradise) on a gravel parking lot which backs up onto a large grass area and the lake. Fisherman's Paradise is quite nice but when it fills up on weekends the spacing is pretty tight. This park is a wonderful place to spend a few days or a week. There are some nice hikes right from the campground and several outstanding hikes in the surrounding national forest. The lake is beautiful with good fishing and the fall color here is spectacular. The last five miles of the road to the lake are very well-maintained gravel--not a problem for RVs, just a bit bumpy in spots. We would not hesitate to come back here again. - MrSunshine
Jun 2013 - $18.00
Great getaway! This park is well-run and although we did not have any hookups, we thoroughly enjoyed the peaceful surroundings of a mountain camping experience. The sites are well-spaced and the restroom / shower facilities were very nice. Note that the campground is another five-mile drive in on a gravel road after the visitor center at the entrance to the park (a total of 15 miles from the nearest town of Eagle). We would definitely stay here again. Be sure to make your reservations early. - charms51
Carbondale, Colorado (map) | (970) 704-4190
Sites: 23 | Latest Rate: $31.00 | 2 Reviews
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Aug 2015 - $31.00
This is a lovely little park that is extremely well run by 2 sets of camp hosts. They are very attentive and will help in any way they can. The sites allow for a private outdoor setting with your own picnic area. The park would be a 9 if it did not have the road noise. The highway proximity does make for a good bit of that. Being on the bike path and so close to the river make up for the traffic. - rickimcm
Sep 2011 - $35.00
The City of Carbondale has recently taken over what used to be called the Mount Sopris RV Park. Sewer connections are difficult to reach. Lots of traffic noise from Highway 133 and Highway 82. Access to park is difficult and not marked on Highway 133. There is only a green RV sign with an arrow. I'm sure this park will improve with time. Good cell coverage. Convenient location. - silverfox9
Basalt, Colorado (map) | (970) 945-2521
Sites: 25 | Latest Rate: $20.00 | 3 Reviews
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Sep 2014 - $20.00
Dump station additional $7 and must get a key from the Maud Campground host. Peaceful and quiet with only the sound of rustling aspen trees or an occasional jet airplane. Change - now can be reserved online, which we did not do. So we could only pay for one night at a time, which was not a problem when we stayed after Labor Day weekend. Made private by small trees and bushes, the large gravel sites - some are more open to the sun, with beautiful views to the lake. Others sites further up the hill are shaded in the trees. Most sites are not level front to back due to the hillside location of the campground. Nearby fishing access to the Gold Medal Waters of the Frying Pan River (special regulations). No Verizon phone and MiFi connections. We will return. - AluminumCloud
Sep 2013 - $18.00
One of my favorite places. Although the maturing trees have been closing in my view to the lake, I enjoy sitting out in this campsite. The pines are deeply blue green, the aspens rustle in the smallest cool breeze, and the babbling brook meanders down the campsites tucked into the bubbly vista. The road into the White River National Forest is gravel and continues into the campgrounds and campsites. Little Maud campground is close to the Reudi Reservoir and many boaters camp there. Mollie B campground is the next campground and has access to the lake. Just down from the campgrounds gold medal trout waters flow and are fed from the bottom of the lake. We will return. - AluminumCloud
Jun 2013 - $18.00
Little Mattie is one of 3 campgrounds on the western end of the Reudi Reservoir along the Frying Pan River. There are no hookups at these campsites.Water is available at Mollie B campsite. This is dry camping at its best; sites are nestled in the aspen groves at the base of rock outcroppings and well worth the drive around the bend beyond the other two campgrounds. Vault toilets are the only amenity and well kept and cleaned. Space between each site provides privacy and our favorite was site 16. Big rigs could not fit in here. You can run your generator for power. Drawback to this campground is that it is run by a company in California, not the Forest Service. There is an extra $7 fee to use the dump station and the camp host has to be there to unlock it. Overall, a wonderful place to camp while enjoying the fantastic fishing on the Pan River and the charming town of Basalt. - The Grizz


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Bradley family reunion
Daniel Bradley is a big reason why the NIACC Baseball Team is 34-12 this season.
Sponsored by:
Daniel Bradley is a big reason why the NIACC Baseball Team is 34-12 this season.
Highlights include SWCC/NIACC (BB) and B-K/Osage (Golf).
NIACC won its 11th straight game, but then Southwestern would snap the Trojans winning streak in game two.
The Warriors weren't able to end the season with a win Saturday.
Highlights include: Drake Relays, Minot/Austin, Iowa Challenge 115 and Doebel signs with NIACC.
It was a fantastic Friday for local athletes in Des Moines.
Highlights include: JM/AL (Baseball), CBC Golf (B+G) and an update from the Drake Relays.
Bo Hjelle leads a strong group of area athletes to Des Moines this week.
Highlights from Austin at Albert Lea (SB).
Waldron (69) has the third best round in the state so far this season.


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News about reggae music, artists, culture and more...
These last years, the roots and dub sound system scene is riding high in France. Parties increase in many towns of the country as well as new productions. Here is a new release entitled "French Town HiFi - Vol.1" that will give you a good overview of this French roots and dub stepper movement. This new 35 tracks compilation - including vocals and dub - comes on a double CD and features tracks previously out on vinyl as many unreleased cuts. French Town Records gathered singers such as Mo'Kalamity, Fu Steps, Marina P, Ras Mykha… and dub producers such as Barbes D, Jacin and Ackboo.
As the title of the release suggest, a second volume should follow... Time will tell. Play it loud and stay tuned!
Mr Money Man Riddim
By Angus Taylor
New Albums from Etana and Protoje
By Erik Magni
Paint Jamaica
By Erik Magni
Stephen Marley - Revelation Part II: The Fruit Of Life
By Erik Magni
Positive Vibration Festival 2016
By Erik Magni
Ernest Ranglin Retires from Live Performance
By Angus Taylor
Reggae, Dubs and Dabs
By Erik Magni
Tonight by Isha Blender
By Erik Magni
© 2007-2016 United Reggae. All Rights Reserved. Reproduction in whole or in part is prohibited. Read about copyright
Terms of use | About us | Contact us | Authors | Newsletter | A-Z


text:
Vitter to return to Senate next week, colleague says
Published: Thursday, July 12, 2007 at 6:01 a.m.
Last Modified: Friday, July 13, 2007 at 3:36 p.m.
WASHINGTON -- Louisiana Sen. David Vitter, who has been in seclusion since acknowledging dealings with a Washington escort service, "will be back next week," said a Senate colleague who has exchanged messages with him.
Sen. Jim DeMint, R-S.C., who has traded e-mails with his fellow Republican, told reporters that he expects Vitter to return to the Capitol by Tuesday, when the Senate will have roll call votes.
Vitter, 46, missed votes on Iraq policy matters on Tuesday, Wednesday, Thursday and Friday. DeMint said his understanding is that Vitter has spent the week in Louisiana with his wife and their four children.
"That's the sense I got from trading e-mails," DeMint said.
Vitter's staff has declined to disclose his whereabouts or plans.
In a statement issued Monday night, Vitter apologized for committing a "very serious sin," acknowledging that his Washington phone number was among those called several years ago by an escort service that prosecutors say was a prostitution operation. Telephone records show that the service called Vitter's number five times from 1999 to 2001, while he was a U.S. House member.
DeMint, who generally shares Vitter's conservative philosophies and who joined him in derailing a major immigration bill backed by President Bush, predicted that senators will welcome their colleague back despite his admission.
"It's a huge moral failure that reflects on the whole body," DeMint said. "And for that he's very sorry."
"Obviously he has a lot of remorse," DeMint said. "He seems to want to address it head on and not try to hide it."
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Quilt has been bound and 31 patches have now been hand sewn to the quilt. I am currently in the process of hand quilting each one.... then I will be finished!
yahaira, cauchy09, Mel Sews, and 26 other people added this photo to their favorites.
you are so awesome!
I love the greens with that pop of red
Amazing work - love the colors and your hand-quilting is fabulous!!
This is really amazing! Isn't it very difficult to hand quilt through the patches?
Thanks to each of you!
Ann, not nearly as hard as I thought it would be... except for when the patch covers two joined sections of the first layer... like the left side of the red patch above... then it gets tough!
It's glorious- I love the colors and texture!
The texture is delicious :)
Victoria, I am helpless before your quilts. I stare at them with a contented smile on my face... I love hand quilting and this is just a phenomenal example of it.
I just love this quilt! I thought it was wonderful before the addition of the patches..they make it over the top fantastic! I want to pet it. :)
faboulously gorgeous!!!
crazy cool. I'm loving the texture!
Thanks again to each of you... your lovely comments put a real smile on my face!
Love the combination of hand and machine stitching - the texture is wonderful!
Love this!!! Are you just doing the hand quilting with regular thread?? It looks thicker than that. I love the effect it gives, though!
Thanks to both of you!
iwishmynamewasmarsha.... I am using Sulky's "Premium Egyptian Cotton" thread, in both the 12 and the 30 wt. (whatever I happen to have on hand, and I don't mind using both in the same quilt, in fact I like the variation). Also, I double the thread over so that I am sewing with two threads.
wow. cool!
Thanks for answering! I'll have to look for some of that thread, or something similar- this is inspiring me so much!! I just saw the finished quilt on your blog, and it looks amazing!


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Connect any celebrity with Tracy Seylaz to see how closely they are linked... romantically!
Who`s Tracy Seylaz??
How come you don`t have pictures of her yet?
she did date richie sambora. he should be listed.
i read that tracy seylaz was a model. any pictures of that.
do you have any pictures of her.
any picture of her. i think she used to be a model.


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Join the 'Lipitor' group to help and get support from people like you.
Lipitor Questions
We found 262 questions associated with the 'Lipitor' topic.
Which drug is better - Simvastatin or Lipitor? Which does less damage to the body?
I was prescribed Lipitor by my physician. But I heard that Simvastatin (Zocor) has less of a negative effect on the body than Lipitor. Is it true?
Posted 13 Aug 2009 • 7 answers
Side effects if you stop taking lipitor and you have been on it for 3years?
what will happen if you stop taking lipitor cold turkey
Posted 30 Dec 2011 • 3 answers
Can Lipitor cause Type II Diabetes?
Popular Statin Drug Lipitor causes Type II Diabetes in Women ◦digg ◦ ◦ 5775EmailShare Some women taking Lipitor (atorvastatin) for high cholesterol problems developed type II diabetes, an unexp ...
Posted 26 Jul 2013 • 1 answer
Are leg cramps the same as "muscle pain" described in Lipitor symptoms?
I get a lot of cramps, mostly legs but also in rib cage, hands, etc. Seems like they started a couple years ago, I'm now 60 yrs old. Sometimes I relate these to physical exertions during the ...
Posted 25 Oct 2012 • 4 answers
Does lipitor work better if you take it at night?
Posted 9 Jun 2011 • 3 answers
How long does muscle pain as a side effect last after discontinuing lipitor (statins)? I have 2 mnth
Had the same problem with the other statins, muscle aches stopped after about a week after discontinuing. Lipitor worked for me for over a year before problem started. I developed the side effect in ...
Posted 6 Oct 2011 • 2 answers
Can I use nail polish and Jublia?
simple question
Posted 25 Jun 2016 • 0 answers
Atorvastatin - Have taken lipitor for only six months...increase sweating and shoulder pain even?
... with cortisone
Posted 2 Jun 2016 • 0 answers
Lipitor - if cholesterol is low is a high dose helpful after a stient?
114-41-31 ben on 10 dose now on 80
Posted 20 May 2016 • 0 answers
Interaction with lipitor and alcohol?
My son is an alcoholic he took lipitor and his triglycerides went from 2900 to 8000 he needed dialysis if he continues to drink can he even take cholesterol meds?
Posted 8 Jan 2016 • 1 answer
Should a person with Type-2 Diabetes be taking all the following medicine at once?
Actors- 30mg Lotrel- 20/40mg Hrdrochlorothiazide- 25mg Zetia- 10mg Lipitor-80mg Januvia-100mg Invokona-300mg Metformin-1000mg
Posted 17 Mar 2016 • 1 answer
Can Lipitor cause anger and anxiety?
I just started about now week ago and have noticed I am depressed, irritable and feel like jumping out of my skin. My heart is pounding.
Posted 12 Mar 2016 • 2 answers
93 year old 100 lb lady taking 80 mg of Lipitor?
Could this have anything to do with tongue thrusting? And isn't that a lot of Lipitor? She did have a heart attack 15 years ago and had a stint put in
Posted 9 Apr 2016 • 0 answers
All statins can cause severe muscle/joint pain. I stopped taking Lipitor because of this. Some?
... 'bright' Rheumatologist diagnosed me w/RA and said it was not the Lipitor. After the Methotrexate she gave me almost killed me I threw it and the Lipitor away, and a few months later ...
Posted 6 Jul 2013 • 1 answer
Can I abruptly quit lipltor?
My Dr put me on Lipitor recently, after taking for a while, I feel very fatigue and body and muscle pain.
Posted 27 Feb 2016 • 1 answer
Ask a Question
Further Information
Related Condition Support Groups
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Lipitor Patient Information at Drugs.com
- Lipitor Information for Consumers
- Lipitor Information for Healthcare Professionals (includes dosage details)
- Side Effects of Lipitor (detailed)


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PhD/Graduate Teaching Assistant at the University of Reading
Posted on July 14th, 2016 in Fellowship, PhD, Scholarships • Respond to this post »
Deadline: 1 August 2016 Open to: candidates with strong research interest and ability in Archaeology, Geography or Environmental Science Remuneration: fully funded for four years as a research student studying for a PhD (75% of time) and a teaching assistant (25% of time)Description
Applications are invited for the post of Graduate Teaching Assistant. The appointed person will be registered for a Part-Time PhD, while holding a contract of employment from the University of Reading which encompasses both doctoral studies and teaching responsibilities with an associated salary.
This innovative participatory action research (PAR) project will explore how family relations and an ethics of care are sustained across space in the context of forced migration and seeking asylum in the UK.(adsbygoogle =... Read More »


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July 26, 2010 2:20:00 PM
Mississippi University for Women English professor, Dr. Nora Corrigan, will appear on the game show, "Jeopardy," set to air locally at 11 a.m. Tuesday on WLOV-TV.
Originally from Reston, Va., Corrigan holds multiple degrees in English from The College of William & Mary and University of North Carolina at Chapel Hill. She spent a year as a visiting assistant professor at McKendree University in Illinois before starting at MUW in August 2008. She currently teaches Shakespeare, English Literature I and II and composition.
Corrigan has always liked playing trivia. "Back in grad school, my friends and I used to have epic all-night games of Trivial Pursuit, and I''ve really missed that since I moved here, so I decided to take the online `Jeopardy'' test just for fun. I was very surprised that I actually ended up on the show," she said.
The screening process to be on the show had two stages. The first part was an online quiz of 50 questions with a strict time limit. After Corrigan passed the quiz, a "Jeopardy" staff member contacted her to travel to one of the cities where they conducted an in-person audition. The audition consisted of a written test, a practice game with buzzers and some practice interviews.
Corrigan was called by "Jeopardy" producers in February and flew to Los Angeles for the taping of the show in March.
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Book your room at Homewood Suites by Hilton Columbia
Located within a leisurely stroll of Riverbanks Zoo and Garden, Homewood Suites by Hilton Columbia is within a few miles (5 km) of Earlewood Park. This 3-star hotel has 81 rooms and welcomes guests with free breakfast, an indoor pool, and free in-room WiFi. Located centrally in Columbia, it's also near South Carolina State House and Palmetto Health Heart Hospital.
Free hot/cold buffet breakfast is included with your stay and awaits you each morning. For a nice break, mingle with other guests at the free manager's reception.
All 81 air-conditioned accommodations feature kitchens and space to spread out with dining areas. 32-inch LCD TVs come with cable channels and DVD players, and guests can stay connected with free WiFi and wired Internet. Pillowtop beds sport down comforters and bathrooms offer hair dryers and free toiletries. MP3 docks, sofa beds, and coffee makers are other standard amenities.
Property features
Guests of Homewood Suites by Hilton Columbia have access to an indoor pool, a fitness center, and a spa tub. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry and concierge services. Additional amenities include free WiFi in public areas, a business center, and coffee/tea in a common area.
- Free hot/cold buffet breakfast
- Free WiFi and wired Internet in rooms and public areas
- Free parking
- Indoor pool
Homewood Suites by Hilton Columbia230 Greystone Blvd Columbia SC 29210-8005
Hotel Amenities
Hotel Amenities
In addition to an indoor pool, Homewood Suites by Hilton Columbia provides a spa tub and a fitness center. High-speed wired and wireless Internet access is complimentary. This 3-star property offers access to a business center. Guests are offered a complimentary breakfast each morning and a complimentary manager's reception is offered on select days. Event facilities measure 1400 square feet (126 square meters). This business-friendly hotel also offers a library, barbecue grills, and multilingual staff. Concierge services and a complimentary grocery shopping service can be provided. Onsite self parking is complimentary. The property may provide extended parking privileges to guests after check-out (surcharge).
Homewood Suites by Hilton Columbia has designated areas for smoking.
- Fitness facilities
- Business center
- Number of floors - 5
- 24-hour front desk
- Express check-out
- Total number of rooms - 81
- Library
- Free self parking
- Free grocery shopping service
- Conference space size (meters) - 126
- Spa tub
- Barbecue grill(s)
- Coffee/tea in common areas
- Free newspapers in lobby
- Free breakfast
- Concierge services
- Dry cleaning/laundry service
- Elevator/lift
- Express check-in
- Fireplace in lobby
- Designated smoking areas
- Grocery/convenience store
- Free WiFi
- Free wired high-speed Internet
- Laundry facilities
- Multilingual staff
- Number of meeting rooms - 3
- Free reception
- RV, bus, truck parking
- Year Built 2004
- Conference space size (feet) - 1400
- Number of buildings/towers - 1
- Indoor pool
- Television in common areas
Family Friendly Amenities
- Family Hotel
- Indoor pool
- Free Wi-Fi
- Kitchen
- Grocery/convenience store
- Laundry facilities
- Separate dining area
- Sofa bed
- Full-sized refrigerator/freezer
- Microwave
- Cribs/infant beds (complimentary)
- DVD player
Available in all rooms: Free WiFi , Free wired high-speed Internet
Available in some public areas: Free WiFi , Free wired high-speed Internet
Free self parking, RV, bus, truck parking
Room Amenities
- Free cribs/infant beds
- Premium TV channels
- DVD player
- Air conditioning
- Phone
- Kitchen
- Microwave
- Private bathroom
- Shower/tub combination
- Iron/ironing board
- In-room safe
- Hypo-allergenic bedding available
- Ceiling fan
- In-room climate control (air conditioning)
- Free weekday newspaper
- Free local calls
- Coffee/tea maker
- Daily housekeeping
- Free toiletries
- Hair dryer
- Sofa bed size
- Connecting/adjoining rooms available
- Desk
- Sofa bed
- Cookware, dishware, and utensils
- Blackout drapes/curtains
- MP3 docking station
- Separate dining area
- Dishwasher
- Full-sized refrigerator/freezer
- Stovetop
- Cable TV service
- Free WiFi
- Free wired high-speed Internet
- Down comforter
- Pillowtop mattress
Where to Eat
Guests are offered a complimentary hot/cold buffet breakfast each morning. A complimentary manager's reception is offered on select days.
Nearby Things to Do
An indoor pool and a spa tub are on site. Other recreational amenities include a fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Rafting nearby
- Kayaking nearby
- Sailing nearby
- Water skiing nearby
- Hiking/biking trails nearby
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- Accessible bathroom
- In-room accessibility
- Roll-in shower
Hotel Policies
Check-in time starts at 4 PM
Minimum check-in age is 21
Check-out time is noon
Payment types
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
No rollaway/extra beds available
Hotel Name
- Columbia Homewood Suites
- Homewood Suites Columbia
- Homewood Suites Hilton Columbia
- Homewood Suites Hilton Hotel Columbia
- Homewood Suites Hilton Columbia Hotel
- Homewood Suites Columbia Hotel Columbia
- Homewood Columbia
We should mention
This property's policy is to refuse certain bookings for the purpose of group events or parties, including pre-wedding stag/bachelor and hen/bachelorette parties. Children 18 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


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Piggy Nutella Sandwich: Yummy!
Oink oink ~~~ Check out this piggy Nutella sandwich. Who won't want to have a bite?
Here is how to make it:
If you like the ideas on this blog, please give me a "like" on Facebook or follow me on Twitter to get instant notifications of new fun food ideas! Thank you. Tweet Pin It
29 comments:
pero que bonito asi no hay niño que se resistaReplyDelete
Cute piggy sandwich..:)ReplyDelete
Siew Hwei, thank you so much ^^ReplyDelete
Lola, gracias alegra gue te quste!
Cute piggie sandwich. Wish i could take a bite on it..xixixi..ReplyDelete
awww soo cute piggy sandwich...my daughter loves Nutella, i will definitely try to make this for her, Thanks for sharing Tifanny:-)ReplyDelete
I would eat one or two. Nice idea !!ReplyDelete
very very funny "merenda".ReplyDelete
We well try this afternoon....
so cute...thanks for the great ideaReplyDelete
awesome - i love it! oink oink.ReplyDelete
wow congratulations. And this is exactly why! Your blog, and especially your tutorials! are awesome!ReplyDelete
I guess not only kids, we all love Nutella sandwich too! Oink Oink thank you everyone ^^ReplyDelete
This is adorable! Who wouldn't love to have this for lunch?!ReplyDelete
Adorable step-by-step, piggies are such cheerful lunch buddies...!ReplyDelete
it's so nice! Ill'do it for my daughters! Thank for the idea. KissesReplyDelete
Thank you Erin, Bentobird and daniela. Happy Sunday ^^ReplyDelete
yum yummy :)ReplyDelete
Thank you thank you ^^ReplyDelete
- AnonymousApril 29, 2011 at 5:41 AM
umm...looks yummy, definitely going to try it! thankyou, tiffanyReplyDelete
You are so welcome. Glad you like it ^^ReplyDelete
I love this blog!ReplyDelete
I am a fan!!!!
Thank you so much Equipo.ReplyDelete
Have a nice weekend. Hopefully I will see you back here again!
I featured these on my blog today...thanks for the fabulous idea!!ReplyDelete
Lola, gracias alegra gue te quste!ReplyDelete
Reteta asta arata incredibil.MultumecReplyDelete
This is easy.. simple and creative.. ur a great mom ♥♥ God blessReplyDelete
So cute, but I think it will be a little difficult for me to finish!ReplyDelete
Excellent article. Keep posting such kind of information on your site.ReplyDelete
my site: Susu Yang Baik Untuk Memutihkan Kulit


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{"startRecording":} object
Allows Tropo applications to begin recording the current session. The resulting recording may then be sent via FTP, an HTTP POST/Multipart Form, or to your Amazon S3 bucket.
Tips and Tricks
- Recording files are 16 bit, 8KHz files, regardless of the audio type
- If you record a conference or a transfer, you'll get a stereo recording. One channel contains the caller, the other contains the conference or transferred party.
- Transcription results will be better if you use WAV as your audio type. The higher-quality audio gives more for the transcription engine to work with.
Setting to true will instruct Tropo to upload the recording file in the background as soon as the recording is completed.
If this is set to false (the default behavior), Tropo will wait until the file is uploaded before returning or running the onRecord callback.
This specifies the format for the audio recording; it can be 'audio/wav', 'audio/mp3' or 'audio/au'.
For HTTP or S3 recording upload, this parameter determines the method used. To upload to an Amazon S3 bucket, use "s3". For HTTP, this can be 'POST' (which is the default) or 'PUT'. When sending via POST, the file is sent as if you uploaded in a web form with a form field name of "filename".
The S3 Bucket, FTP, or HTTP URL to send the recorded audio file. When sending via POST, the name of the form field is "filename". Accepts SSL (FTPS and HTTPS) and SFTP URLs as well.
The file will take a few moments to upload to your server. The exact amount of time depends on many factors, including the network connection of your server. If your application needs to play back the audio immediately after recording is completed, the object returned by the record method has a "value" property that contains a url of a temporary local copy of the file. This temporary copy will be deleted as soon as the call ends.
Please note this needs to be a fully realized URL, i.e. "http://website.com/folder/subfolder" vs "/folder/subfolder". If you don't have a complete URL, the file won't send at all or at the very least won't send correctly (0 byte file and similar unusable content).
For FTP or S3 destinations, include the full URl including the file name, i.e. "ftp://example.com/folder/my-recording.wav" or "https://s3.amazonaws.com/your_bucket_name/myrecordng.mp3".
Defines the username for uploading your recording. For HTTP, this is a Basic Auth user.
For FTP, this is your FTP server's user name.
For S3, this is your AWS Access Key ID.
Note: If user name contains @ or /, the character must be URL encoded.
Defines the password for uploading a file. When using HTTP, this will be used as a password for Basic Auth to your server.
For FTP, this is your FTP user name.
For S3, this is your AWS access key secret.
Note: If password contains @ or /, the character must be URL encoded.
Specifies the encoding used when delivering transcriptions via e-mail. Values can be "plain" or "encoded".
User definable ID that can be included when the transcription is posted to transcriptionOutURI.
Setting this to anything enables transcription on this recording. The e-mail address or HTTP URL to send the transcription results to; the transcription arrives as the content of the HTTP POST, as opposed to a header, named field or variable, and is not sent as form data.
Note: Email addresses must be prefaced with mailto: if used (mailto:firstname.lastname@example.com)
Transcription is a paid feature and is not included in the per-minute rate for phone calls. Transcription is billed for each minute of transcribed recording. See Tropo Pricing for current rates.
Example with stopRecording
{ "tropo":[ { "startRecording":{ "name":"myrecording", "url":"http://example.com/getrecord.php" } }, { "say":[ { "value":"I am now recording!" } ] }, { "stopRecording":null } ] }


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Older Adult and Caregiver Services
Free Teleconference Series
Have a question about an aging related issue for you or a loved one?
The Older Adult and Caregiver Services program has answers!
The second Wednesday of every month, from 12:00pm-1:00pm, we will host a FREE, phone-based discussion.
Click on the links below to register for the topic(s) that interest you.
You can also register by calling 303.217.5864 or 970.232.1180
August 10th - Aging in Place: Part 2
Part 2 will address questions on health and wellness, such as whether or not you have access to the health care you need. We will also discuss issues often not considered in the Aging in Place process, including community and social interactions, as well as access to the entertainment and education you prefer.
Call today for more information or to make a referral!
303.217.5864 or 970.232.1180


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search results - Road Bike Shop
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Price: $149.95
|Giro New Road CA Ride Crew Pockets Jersey - Short Sleeve - Men's
Made to be a versatile T-Shirt-inspired riding layer, Giro's Ride Crew Short-Sleeve Jersey was designed and sewn in California, and it was given sharp details that combine the best of jersey and T-Shirt designs into one. To start, Giro used its Nycore merino blend, which adds the durability of...
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Price: $159.95


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Private Tour: Great Wall of China at Juyongguan and Ming Tombs from Beijing
Review score
Private Tour: Great Wall of China at Juyongguan and Ming Tombs from Beijing information and booking
Tour description provided by Viator
See the best of China's ancient civilization on this private full-day trip from Beijing to the Great Wall of China and the Ming Tombs. At the Great Wall, you'll climb the Juyongguan section, one of the most strategically important sections of the wall. You'll also explore the Ming Tombs, the burial ground of 13 Ming Dynasty emperors.
Begin your private day trip from Beijing at the Great Wall of China, the greatest symbol of Chinese engineering and one of the New Seven Wonders of the World. Spend the morning climbing the wall at Juyongguan, a famous pass through the mountains located in an 11-mile-long (18-kilometer-long) valley.Surrounded by mountains, Juyongguan Pass served as a strategic military stronghold and was the site of many battles. The ancient pass was originally built in the Han Dynasty (220-206 BC) as a fortification, and later rebuilt to link it to the Great Wall of China. The circular pass is complete with supporting facilities, including a city tower, watch tower and a meeting place for the emperor. Juyongguan is surrounded by lush forests and magnificent mountains.Enjoy lunch at a Chinese restaurant before heading to the Ming Tombs for a glimpse of ancient Chinese history and imperial culture. Enter the tombs through the Great Red Gate, covered with imperial yellow roof tiles. As you make your way down the main road called the Spirit Way, see the 36 impressive stone statutes of guardian officials and animals carved in the 15th century. Continue your walk down the path to explore the Chang Ling Tomb. The Chang Ling Tomb is the largest and best-preserved of the Ming Tombs and is divided into three stunning courtyards.
What's included
- Private vehicle for hotel pickup, drop-off and sightseeing
- Transportation to and from juyongguan section of great wall and ming tombs
- English-speaking private guide
- Lunch
What isn't included
- Gratuities (optional)


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Goffstown High School Alumni
Goffstown Alumni Photos
What is this site?
- Send messages to alumni
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Click on the Yearbooks below to view a copy Online at Classmates.com®. If you don't see your class's yearbook, check out our yearbook page.
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- Class of 1998 Anne Hill
- Sterling Chambers
- Drew Consell
- Class of 1996 Jeff Coplan
- Class of 1984 Steve Lockwood
- Class of 1995 April Iverson
- Joseph Slack
- Class of 1976 Joanne Swindlehurst Malia
- Doug Moss
- Drew Counsell
- Class of 2010 Steven Beard
- Josh Williams
- Class of 1984 Nancy Hamel
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This site has been created for the former students of Goffstown located in Goffstown, New Hampshire. We also encourage you to keep up to date on news and reconnect with Goffstown High School alumni. You can also find out what other graduates are doing now, share memories with other alumn, upload pictures from GHS and find other alumni.


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U.S. Policy
Iran's Airbridge to Syria
Iran is muscling up. We should push back
Reports are swirling that Russia is finally delivering an advanced S-300 air defense system to Iran, although they may be premature again. The implications of that and the other items on Iran's military shopping list need our attention fast.
An Iranian military hardware spree can quickly fuel a Middle East arms race, drive U.S. allies to seek more advanced weapons, and, in the case of Israel, spur development of their own.
Iran Tracker Blog: Iran has no qualms about exploiting the nuclear deal's weaknesses
If there is one thing the Iranian leadership wants you to know, it is that the recently signedJoint Comprehensive Plan of Action (JCPOA) will not in any way compromise Iran's ability to defend itself from military coercion or attack. The language in the United Nations Security Council Resolution (UNSCR) 2231 endorses the nuclear deal, but also continues the ballistic missile and conventional arms embargoes for e
Iran Tracker Blog: Khamenei has his own tough sell on the nuke deal
Supreme Leader Ayatollah Ali Khamenei is still holding back from fully endorsing last week's announced Iran deal: the Joint Comprehensive Plan of Action (JCPOA). His reticence is smart and to be expected. Khamenei must appear above the fray of Iran's internal politics while in reality he is intimately involved in their orchestration.
Why They're Cheering in Tehran
Iranians celebrate on the streets following a nuclear deal with major powers, in Tehran July 14, 2015. (Reuters).
The Day After A Deal: What To Expect From Iran
A nuclear agreement will inject a large cash windfall into Iran's ailing economy.
Iran Tracker Blog: Near to a nuclear deal, Iran grapples with bigger headaches
As the world is focusing on the yet-again extended nuclear talks, Iranian leaders are expressing ever greater concerns about the perceived threats from ISIS and Saudi Arabia. How Tehran may respond, including deploying ground forces in Iraq, should give everyone pause.
Iran Tracker Blog: Why Phased Sanction Relief is So Hard For Iran to Swallow
Last week there was widespread optimism that a deal on Iran's nuclear program was close. Now a less enthusiastic tone has emerged, especially from Western negotiators, and a key problem appears to be how much and how fast sanctions relief will come.


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Provost's Office
We stand with OrlandoJune 17, 2016 Day of mourning on Thursday capped by campus discussion with Staten Island Pride Center, Islamic Civic Association READ MORE
Wagner student panelist at National Press Club briefingJanuary 26, 2016 Anthropology major Daniela Gutierrez de la Garza was one of three student panelists at a Jan. 20 NAC&U National Press Club briefing. Watch the video of her presentation and Q&A responses. READ MORE
Pulitzer Prize-winning journalist is 2016 Black History Month ScholarJanuary 14, 2016 NYU journalism professor Pamela Newkirk will speak on Feb. 2 READ MORE
2015 Faculty Awards DinnerNovember 20, 2015 Congratulations to the dedicated Wagner College faculty members who were recognized at Tuesday night's annual Faculty Awards Dinner READ MORE
Ken Bain, 'Fostering Deep Learning'November 10, 2015 Author of 'What the Best College Teachers Do' to lead interactive program, Nov. 18 READ MORE
Postponed: Lecture by historian Bruce ChadwickOctober 5, 2015 Due to a death in the lecturer's family, Wednesday evening's Kaufman Repage Lecture by historian Bruce Chadwick will be rescheduled sometime next year READ MORE
Wagner welcomes 4 new faculty membersAugust 26, 2015 Wagner College welcomes four new members to its faculty at the start of the new academic year READ MORE


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Through a series of recent inter-league email exchanges, Sharon has accused me of being unsympathetic and of exploiting her breakup last week. True, I blamed her bad coaching decisions on her recent drama and set our Moral Enforcer, Malia, on her trail for starting a player with a bye. But in all fairness to myself, I never actually considered her drama to be a valid excuse for disregarding her fantasy team. I view breakups as all the more reason to completely immerse oneself in fantasy football, not to ignore it. Regardless, the update on the situation is that Sharon has promised not to let men affect her lineup anymore, and Malia has instituted a new rule called the "Break-up Exemption" on Sharon's behalf:
"Since I've let a lot of other people slide this season who have done the same thing (um, um -- Steph), I'll let this one slide as well. But, from now on, I will be watching lineups and other infractions very closely. Now that I may have a chance to make the playoffs (despite last week's performance), I want that pot to be bigger than ever!"
From the sound of it, I believe this is a one-time exemption, not necessarily applying to any future breakups. But, seeing as I've been called out in the above statement, I will refrain from further comment.
Last week Sharon failed her Dientes Locos at tight end once again, but this time it was because she started Jason Witten instead of Jeremy Shockey, and it cost her 25 points and the game. I know Sharon wants to stick with Witten since she just recently traded for him, and that might not be a bad choice against a Washington secondary that gave up four touchdowns and tons of fantasy points to Philadelphia last week. But it's a tough decision as Shockey faces the weaker Detroit defense that's been making players like Greg Olsen, Tony Scheffler and Leonard Pope look like top fantasy tight ends the past few weeks. My concern with Shockey is that he seems to have big games only every other week, while Witten is more consistent.
Tight ends have also been the issue for the Red Dogs this year. In Week 10 Sarah finally ended her flirtations with Donald Lee and decided to stay loyal to the man she entered the season with, Vernon Davis. It turned out to be a horrible decision last week, as Davis and the 49ers had a forgettable outing against Seattle. And now she's lost Lee for good, as Christina scooped him up and made him the new starter for the Black Widows. Smart move by Christina considering that Lee just signed a nice contract extension, ranks in the top 10 in our league at his position and has Brett Favre throwing to him.
I'm not sure that's any consolation for Christina, though, as I'm certain she is still mourning the defeat her Black Widows suffered at the hands of my Blonde Devils. And I know I was lucky because Tom Brady had a bye, but she really can't complain with the performance her backup Marc Bulger gave her.
It looks like Christina may consider using D.J. Hackett now that he's back in the lineup for Seattle. He's had touchdown catches in each of the past two games, and this week his matchup is against a very average Chicago defense. Not only do they give up a fair amount of yards this year through the air, but the Bears went from having the second most interceptions in the league in 2006 to the second least currently. If Deion Branch is still out this week, Hackett deserves a spot in her lineup. She can put him in either at flex instead of Edgerrin James or replace Santonio Holmes with him. James has a good matchup against the Bengals, and Cardinals head coach Ken Whisenhunt is familiar with this defense from his days as offensive coordinator for the Steelers. So I think the better option is to bench Santonio Holmes. While Ohio State could have used him back in their lineup against Illinois, Holmes was just average against the weak Cleveland secondary. And as much as Hines Ward and Holmes complement each other on the field, they don't put up huge fantasy numbers in the same week.
Another top-ranked team that went down was Courtney's Georgia Peaches, who fell to the last-place Dawg Pound. Courtney's ever-lingering quarterback situation is a little easier this week, as Eli Manning and Jon Kitna's teams square off against each other. While Eli faces the much easier secondary, Kitna looks like he may have found his rhythm again. Plus, I fear this could be the beginning of the end for Eli and the Giants. They entered Week 10 at 6-2 and suffered a devastating loss to the Cowboys, which sounds all too familiar. Let's not forget 2006 when the Giants entered Week 10 at 6-2, lost to the Bears and woke up four weeks later at 6-6. That's not good for Eli's confidence or his stats.
Kate was fortunate that Kurt Warner gave her 26 fantasy points last week, and she really couldn't ask for much more than for him to be facing the Bengals' secondary this week. The strange thing about Warner is that he has yet to hit 20-plus fantasy points two weeks in a row this year. so Kate might want to consider Vince Young at Denver as an alternative. The Broncos secondary has given up some unexpected big games lately, and it might just be Young's chance to finally have one of those big games.
Another Titans player being overlooked in our league this week is LenDale White, who Allison has already benched for Week 11. She might want to reconsider, though, in light of the fact that he's returning to his hometown in Denver for Monday Night Football against one of the worst rush defenses in the league. I can already envision White being interviewed by Michelle Tafoya after the game discussing how meaningful it was for him to return home and have such an impressive performance in front of his friends and family. But this is a tough decision because her other option, Willie Parker, actually faces the league's worst rushing defense in the New York Jets. Despite Parker's matchup, I've never considered him a first-round fantasy back such that he deserves a starting spot each week, and I would actually bench him this week in favor of Jesse Chatman. Chatman has been playing well and scored 17 fantasy points against a Bills defense in Week 11 that statistically isn't that different from the Eagles he'll face this week. He has the added incentive of needing to prove himself before Ricky Williams somehow makes it back into the lineup after being reinstated by the NFL. Plus, Miami is trying out rookie quarterback John Beck this week, so Chatman will need to help carry this team.
Speaking of Beck, I think Leila should pick him up off of waivers. Leila's Cats suffered defeat at the hands of the Dogs in Week 10, (team names are purely coincidental) and it may have had something to do with the fact that she's alternating between Brian Griese and Jeff Garcia at quarterback. No one has seen Beck play yet, so he may get lucky this week. Plus, he threw for 11,021 yards and 79 touchdowns while at BYU. Although we really don't know what he is capable of as in the NFL, the Dolphins saw enough potential in him to pick him up in the second round of last April's NFL Draft.
As for Melanie and I, we both seemed to have found running backs in unexpected places. She has Warrick Dunn, and I have Ryan Grant. Dunn won't replace the injured Adrian Peterson on her Golden Rules roster in terms of points, but he's decided to break out at a rather convenient time for Mel. As for me, I'm just excited to take DeAngelo Williams out of my starting lineup for good.
While we can't quite take advantage of the breakup exemption for technical reasons, Mel and I will be out this weekend toasting our running backs and perhaps discovering a new exemption rule of our own. Sharon, want to join us?


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Capitol Hill Critics Second-Guess Agencies Using...
Co-Sourcing Improves Pharmaceutical Laboratory Productivity
Clinical-Style Validation, Regulation, and Quality Control...
Keep the Opportunities, Lose the Opportunists
Tag-lite is a cellular screening platform from Cisbio Bioassays that enables the investigation of natural ligand, small molecule, or antibody binding to cell-surface proteins such as GPCRs and RTKs. This technology, which combines HTRF and SNAP-tag technologies, can be applied to the discovery and development of therapeutic antibodies against cell-surface proteins.
Tag-lite's high-throughput format is ideal for primary and secondary screening of antibodies and can be applied to a variety of assay formats for pharmacological characterization.
Tag-lite was investigated to screen therapeutic antibodies for their binding to cell-surface protein targets and characterize their affinities. Different assay formats were applied to determine the binding of antibodies to two different receptors: CXCR4, a GPCR belonging to the chemokine family, and EGFR, a tyrosine kinase receptor.
Binding of the antibodies to their targets was detected using Tag-lite. Specific cell lines were designed for each receptor, allowing either binding experiments, functional assays (cAMP, Phospho-Erk) or internalization assays.
Tag-lite starts with the cloning of the gene encoding the receptor of interest in a plasmid containing the SNAP-tag sequence. This SNAP-receptor plasmid is then transfected into HEK cells to produce Tag-lite cells. These cells can be used to investigate the activity of the receptor via functional tests or can be specifically labeled on the SNAP-tag using SNAP-Lumi4 Tb substrate. The labeled cells are then used for different applications, like ligand-binding assays, dimerization, and internalization (Figure 1).
To detect the binding of antibodies on cell-surface receptor targets, different assay formats were designed. Antibodies were screened by displacing different types of ligands—a labeled natural ligand or a labeled antibody—away from the receptor of interest. In this case, antibodies were detected by their binding to the ligand site. Antimouse Fc-d2 labeled antibody was also used to detect the binding in an indirect assay format (Figure 2).
Reagents: SNAP-Lumi4-Tb, antimouse Fc-d2, SNAP-CXCR4, and SNAP-EGFR plasmids and the labeling medium were from Cisbio Bioassays. Lipofectamin 2000 was purchased from Invitrogen, and the cell-dissociation buffer was from Sigma Aldrich. Anti-CXCR4 antibodies (12G5 and 44717) and anti-CXCR7 antibody (11G8) were from R&D Systems.
Covalent labeling of SNAP-receptor cells: A solution of Tag-lite SNAP-Lumi4-Tb substrate at 100 nM was prepared in Tag-lite labeling medium. After aspiration of the cell culture medium, 3 mL of this solution was added to the cells expressing the SNAP-receptor in the T175 flask, followed by a one hour incubation at 37ºC. The cells were then washed four times to remove the excess of SNAP-Lumi4-Tb and detached using the cell dissociation buffer. The cells were frozen under 1 million cells/vial in culture medium and 10% DMSO.
Ligand binding assay: The SNAP-Lumi4-Tb labeled cells were thawed and washed with PBS, then resuspended in labeling buffer. Binding assays were performed in a total volume of 20 µL in 384-small volume white plates. 10,000 cells/well were incubated for one hour at room temperature with different concentrations (0–200 nM) of labeled ligand (SDF1-red, mAb anti-CXCR4-red) or unlabeled ligand (mAbs anti-CXCR4). 100 nM of antimouse Fc-d2 was added for the detection of unlabeled mAbs.
Competition binding assay: Competition binding assays were carried out in a final volume of 20 µL in 384-small volume white plates. 10,000 labeled cells were incubated with red-labeled SDF1 or red-labeled EGF (final concentration of 12.5 nM or 10 nM respectively) in the presence of different concentrations of antibodies (0–100 nM). Following incubation, the plates were measured on a TR-FRET reader.
cAMP functional assay with cAMP dynamic 2 kit: The functional tests were performed in 20 µL final volume in a 384-small volume plate. 10,000 cells were incubated with Forskolin (2 µM final concentration) and different concentrations of SDF1 or 12G5 antibody (0–1 µM final concentration). The plates were incubated 30 minutes at room temperature before being read on a TR-FRET reader.
Internalization Assay: Internalization assays were carried out in a final volume of 20 µL in 384-small volume white plates. 10,000 labeled cells were incubated at room temperature with a high concentration of internalization reagent in the presence or not of different concentrations of SDF1. The plate was measured after a two-hour incubation.
Jean-Luc Tardieu, Ph.D. ([email protected]), is product manager at Cisbio Bioassays. SNAP-tag is a trademark of New England Biolabs.
Jean-Luc Tardieu, Ph.D. ([email protected]), is product manager at Cisbio Bioassays. SNAP-tag is a trademark of New England Biolabs.
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MDMA (commonly known as the empathogen "ecstasy") is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.Do you agree that ecstasy should be studied for its potential therapeutic benefits?
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