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A massive HIV test-and-treat study is underway in Kenya and Uganda. Migratory men in the fishing industry there have been hit especially hard, and researchers are trying creative ways to encourage them to get tested. William Brangham reports from Mfangano Island with support from the Pulitzer Center on Crisis Reporting for our series, "The End of AIDS?"
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In world news this week, Kenyans torched tons of a precious product, a Turkish official quit, and an Aussie claimed to create bitcoin. Oh, and did we mention it was Star Wars Day? Take our quiz on this and more. Continue reading
The Kenya Wildlife Service burned the largest stash of elephant tusks and rhino horns ever assembled in one place on Saturday. It was an effort to eliminate the prized but illegal ivory from the market. Continue reading
In message to poachers, Kenya sets ablaze more than 100 tons of confiscated elephant and rhino tusks
More than 115 tons of elephant and rhino tusks confiscated by authorities were set ablaze in Kenya on Saturday to draw attention to the country's continued fight against poaching. Continue reading
More than 100 Kenyan troops died in a January attack by terror group al-Shabab. Last week, the group released a video of the operation. As al-Shabab makes gains, is it also winning the propaganda war? Special correspondent Nick Schifrin takes a closer look at the group's messaging in cooperation with the Pulitzer Center on Crisis Reporting. Continue reading
Kenyans have been listening to country for 50 years — ever since Kenya gained independence from Britain. The songs were especially popular in the country's farming areas. But the homegrown country music industry in Kenya still has a long way to go. One artist driving the movement forward is Elvis Otieno, known as "Sir Elvis." NewsHour special correspondent Nick Schifrin reports in partnership with the Pulitzer Center on Crisis Reporting. Continue reading
In Kenya, corruption and bribery are commonplace in law enforcement and the government. Many police officers seem more interested in keeping citizens' cash than keeping the peace, allowing criminals to get off. Meanwhile, the government has "misplaced" $999 million. Special correspondent Nick Schifrin and producer Zach Fannin report in partnership with the Pulitzer Center on Crisis Reporting. Continue reading
Al-Shabab, an Al Qaeda-linked militant group based in Somalia responsible for a shopping mall attack in Kenya that killed 67 in 2013, is enlisting more recruits from Kenya than any other country. In the second part of the NewsHour series "Inside Kenya," young men talk about why they joined. Continue reading
Amid the stylish dresses and crimson lips of "MTV Shuga" comes a message of acceptance for those who have HIV. Continue reading
Established by the U.N. in 1991 to house Somalis fleeing their civil war, the Dadaab refugee camp complex in eastern Kenya has grown into the largest in the world. Some call it a humanitarian disaster, but to its half-million residents, it is both their last resort and their home. Judy Woodruff talks to Ben Rawlence, author of "City of Thorns," an inside look at stories of survival in Dadaab. Continue reading


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A/N: Thank you all for your support.
I hope this is worth the wait.
Disclaimer: I don't own it, I just borrow from S.M.
There's no combination of words
I could put on the back of a postcard
No song I could sing
But I can try for your heart
Our dreams, and they are made out of real things
Like a, shoebox of photographs
With sepia tone loving
Love is the answer,
At least for most of the questions in my heart
Like why are we here? And where do we go?
And how come it's so hard?
It's not always easy and
Sometimes life can be deceiving
I'll tell you one thing it's always better when we're together
)*Fifteen Years Later*(
"Hey there, little guy," Sam says, rubbing my swollen belly. I peek at my husband of eight years over my book that have propped up against my every growing stomach. I giggle rolling my eyes, as Sam continues to talk to his son currently located in my uterus.
"I can't wait to see you, neither can Ash or Max." Sam murmurs, pressing a kiss just above my belly button. He continues to lay reverent kisses all over my belly, and I laugh when he presses his lips firmly before blowing on my stomach.
"Enough!" I laugh, swatting him away from my bulging torso.
Sam moves away, coming to lie down next to me on our bed. I close my book, setting it down next to me. I sit up a bit more, yawning as I lay my hand on my round belly. I rub it absentmindedly as I am hit with the thought that the little person residing within will be here in just two months.
His future brother and sister, Max and Ashlin, cannot wait to meet him. I smile as I think of my first born, Ashlin. She looks a lot like me at only seven years of age. She's a lot like her Dad though, quietly observant with a big heart. Max, however, looks much like Sam. He's five year's old with a big mouth (like mine) and is a smart ass thanks to me.
I cannot believe that I am pregnant again for the third time. I mean, I never really thought I was cut from the mother cloth, but apparently I was. Max and Ashlin were the best things that had ever happened to me, with the exception of Sam of course.
Sam, I was sure, was truly made to be a Dad. When Ash was first born he stepped into his role with great ease, and even when she was just a bundle in his arms she had him wrapped around her little finger. She was his little girl, his princess, and she knew it. She was his little piece of Velcro, always at his side. Where Sam was, Ash was. It had been that way since she was born.
Max, though, was my boy. He was two years younger than Ash and much louder. He was like me, with his big mouth and smarty-pants attitude. He sometimes pushed the envelope too far and had to be reminded just exactly who he was talking to. But he was the cutest fiver year old in the world—but then again, I might be a little biased. He was my shadow and often worked with me in the kitchen, watching as I created new sweets to sell at my bakery Sugar and Spice.
I know, right?
But that was me: a baker.
I opened it right after I got out of College, with the Pack's help. The guys helped me get all set up, and were my very first customers. The bakery had been very successful over the years, thank goodness, and I now was able to be at home with the kids a lot more with my success. I only went to work about four times a week now, as opposed to when I first started and was there everyday and night.
Sugar and Spice was my pride and joy (next to Ash and Max of course) and was located in Port Angeles. It was not too big, but not too small, and had just enough space for my ever growing menu. I had a great staff working there and was quite lucky that they had been with me from the very beginning.
I smile when I feel Sam's hand join my own, both our hands resting on my stomach. Our boy kicks from within, as if to acknowledge the attention we're giving him. I open my eyes and turn my head to the left, smile at Sam, "Ready for another one?"
Sam just leans in and places a soft, openmouthed kiss upon my lips. I feel his lips move as he breathes, "Yes, that and the dozen that will follow."
I pull away, laughing, "Funny man."
"I'm serious."
"I am too. There is no way fifteen babies are coming out of my vagina. Let's just play it by ear, okay?"
"Okay, okay, we'll see." He teases, pressing a kiss to my lips.
"You just like seeing me pregnant." I mutter against his hot mouth.
"I can't lie, baby. You're so sexy," Sam growls, kissing the corner of my mouth and up my jaw. "You're so soft and round and delicious."
"And my boobs are bigger." I sigh, knowing that's what he is thinking. He kisses the spot behind my ear, tasting it quickly with a dart of his hot tongue.
"True." He kisses down my neck as his hot hands slide up my sides. I'll never get over it, here I am, fifteen years later and the heat of his touch still shocks me. I shudder, moaning quietly when he stops, only to lay between my open legs.
I place my hands on his broad shoulders, sliding them up to his neck. He dips his head down to kiss me, sending a thrill of desire through me. His mouth is warm against my own as he gently presses against my own, nudging it open. I sigh into his mouth, sliding my tongue out to greet his. He slides his tongue against my own, teasing me in the most delicious way. I draw my legs up around his waist, gently rocking my hips. Sam groans into my mouth as I brush against his stiff boner—I'm thirty two and still refer to his erection as a boner, I know, it's ridiculous—in my search for some friction.
I am just sliding my hands down his torso when I hear the creaking of floor boards. Sighing I push Sam off of me and wait for it. Just as expected my wee man walks in, "I had a bad dream."
Max, looking half asleep in his Super Man pajamas, immediately has my attention. I turn to Sam, who looks disappointed that he's been interrupted, and sigh, "I'll be back."
He nods, watching me as I get up and out of the bed, struggling a little because of my big belly and walk over to Max. I take his hand and say, "Okay, baby, let's go. I'll lay down with you and keep the bad dreams away."
He grabs my hand, slipping his soft little one into my own as I walk down the hallway and slip into his bedroom. I get onto his bed, propping myself up for maximum comfort. Max slides into his bed next to me, nestling into my side, laying his head over my heart. He always does this when he's had a bad dream or upset. I softly run my fingers through his soft brown hair, scratching the back of his neck just where his hair begins to grow. I keep my circuit going and know that he's nearly asleep when he mumbles, "I love you."
"I love you, too," I sigh, planting a soft kiss on the crown of his head. He smells like boy, fresh and soapy. I breathe him in, closing my eyes.
I stay with him until I know that he's okay, not a bad dream in sight. I quietly get out of his small bed and plant a kiss on his forehead. I leave his room and return to my own, hoping that Sam is awake and we can continue where we left off. I walk into our bedroom, only to be met with the sound of soft snores.
I shake my head, smirking.
Sam had been working hard lately, between his shifts as a Police Officer and fixing up the baby's room, he was exhausted. I was thankful that he had stopped Phasing once Max was born. Even though Jake was Alpha now, he still often turned to Sam for advice. Sam still went to Pack meetings, talked to the Council and played a large role within both La Push circles.
Even though Sam had stopped Phasing he still retained the characteristics that he had when he was Phasing. He still was warmer that the average male on our Reservation, but wasn't as warm as the Phasing werewolves. He also could still growl, among other things. But he no longer howled at the moon, though.
I crawl into our bed, snuggling into his warm side. Sam wakes up and tiredly wraps an arm around me, tucking me in closer, "Everything okay with Max?"
"Mm-hmm," I lay my head on his chest. "He was just scared. Needed a little love."
"I need a little love." Sam drawls sarcastically, yawning.
I kiss his chest, feeling my lips burn due to his heat, "We both need some love."
"We were about to get some, too, before Max decided to cock-block."
"Did you just call your son a cock-block?"
"Yup. It's the truth. I love him to pieces but he needs to learn to share his Mom."
"This, coming from the guy who wants dozens of kids."
"Hey, we can get a system. Maybe we should start taking numbers."
I just laugh, "Well, maybe we can get my Mom to babysit soon."
"That sounds like a good idea." Sam kisses the top of my head, and I look up at him.
He smiles down at me, bowing his head to kiss my lips. I kiss him back, before pulling away to yawn.
"Sorry, baby," I say through the yawn. "I'm tired."
He just nods, rubbing my back. I sigh and rub his side, murmuring, "I love you, Sam."
"I love you, Bells."
I close my eyes and take a deep breath, and wait for sleep to take me.
I wake up to little hands on my stomach, gently moving about. I open one eye to see that it's Max who is exploring my hill of a stomach. I smirk and close my eyes, before murmuring, "Rub it too much and your baby brother is going to pop out."
Max's curious eyes dash to mine, "Like a genie?"
I laugh, "Like a genie."
Max giggles with me and I say, "Did I do a good job and keep all the bad dreams away?"
Max smiles and nods, crawling up the bed to wrap his arms around my neck. I hug him back, still half asleep as I do so. It is only now that I realize it's just Max and I in the bed and I pull away, "Where's Daddy?"
"With Ash in the kitchen." My son replies smartly, looking at me with his big brown eyes.
"Uh-oh." I gasp with exaggeration. "Do you think he'll burn breakfast again?"
Sam would never live down that Saturday morning in the kitchen. He had been trying to be nice and make a family breakfast, but it didn't turn out so well. He burnt the pancakes and French toast; needless to say we went to the Diner for breakfast that morning.
Max giggles, nodding in agreement.
I smile at him, "That's my boy."
I am just getting up when I hear from the doorway, "Breakfast is ready."
I look over to see Sam standing there, leaning against the door jam. I smile and get up with a grunt, rubbing my stomach, grumbling, "This seems to get bigger with each day."
Max hops off the bed and dashes towards Sam, who promptly picks him up easily, holding him with one muscled arm, "Hey kiddo, what'd I say about bothering Mommy when she's asleep?"
"Not to." Max says somberly, looking contrite.
"Oh, leave him be, I couldn't have asked for a better wake up call." I walk over to Sam, placing a kiss on his lips. He smiles and pulls away after Max exclaims, "Gross!"
I chuckle, as does Sam. He sets Max down on the ground and we all walk down to the kitchen together. Ash is sitting at the kitchen counter, a spread of crayons surrounding her as she colors quietly. That's one thing I can do—leave Ash by herself. Had it been Max down in the kitchen by himself—I don't even want to think about it.
Ash smiles wide when she sees me and hops off her seat to run over and hug me. I hug her back, burying my face in the crook of her neck as I breathe in. My heart swells with this overwhelming love and I hold her to me tight for a moment, "Morning, Baby-Girl."
"Morning, Mom." She breathes, pulling away after I let her go.
I stand up and survey the kitchen, "Manage to burn anything yet?"
"Ha-ha, funny, babe." Sam says dryly, rolling his eyes as he walks over to the stove. He opens up the oven, pulling out a stack of pancakes that had been warming inside. I smile before sitting down next to Ash and Max. I run a hand through Ash's hair, rubbing her back softly, "How was you're sleep?"
"Good." She picks up a red crayon.
I yawn, and pat my stomach when I feel the baby kick. It was eight o'clock on a Saturday morning; I'm surprised Sam managed to keep the kids in control for so long while I slept. Sam moves about the kitchen, plating the kids' food, cutting up their pancakes into bite size pieces. I get up and walk over to the cabinet that contains our cups. I take out Ash's princess cup and Max's Super Man cup. I poor milk into the both of them and set them down where the kids are sitting.
"I have to go in to work today and pick up Kim's cake." I say, putting the kettle on for my morning tea, I'd rather a coffee, but I can't have any since I'm preggers.
"Okay," Sam says, setting the kid's plates down in front of them. "I've got to go into Port Angeles to pick up her present. So, we should go in around eleven?"
I walk over and begin to put together my own plate of pancakes, saving some for Sam. I pour a healthy helping of syrup all over them and begin to eat my breakfast.
"It's Auntie Kim's birfday party today?" Max asks excitedly.
"It sure is. You remember how to sing happy birthday, right?" I ask teasingly.
"Of course!" Max exclaims and proceeds to sing happy birthday.
Sam shakes his head and sets a mug of tea down beside my plate. I smile at him, "Thank you."
"No problem," He says sweetly, kissing my temple and gently rubbing my belly.
We finish up breakfast and I heard the kids upstairs, preparing to get them ready. I trust Ashlin to get herself ready, but Max, not so much. I pick out his clothes so that he actually matches and doesn't look like he got dressed in the dark. I pull him out of his pajamas and put him in his jeans and red T-shirt.
He smiles once he's done and I tell him to go and brush his teeth. While he's in the bathroom I go and check on Ash. She's just finished getting ready when I walk in and I sit down on her bed, motioning for her stand between my legs. She walks over and I grab the brush from her nightstand table.
I begin to gently run the comb through her, righting all the knots and snarls, "How do you want to do your hair today?"
"Um…up?" She says, handing me an elastic band.
"You got it, boss." I say, pulling her hair up into a ponytail.
She giggles before turning around and glancing at my stomach.
"How much longer?"
"Two months, Sweetie."
"That's so long." Ash complains.
"I know. But before you know it you'll have another little brother."
She scrunches her nose up, "Another boy?"
I smile at her, "Yes, Ash."
She sighs, "I want a sister."
"I know you do."
She sighs again, looking at my round belly, "Why can't you be a girl?"
I laugh, standing up, "Go brush you teeth."
She goes into the bathroom and Max walks out smiling brightly. I crouch down, "Breath."
He opens his mouth, and sighs, blowing a gust of air towards me. I breathe in, "Minty fresh. Good boy."
He smiles, "Minty fresh."
I walk into my bakery, Max and Ashlin trailing behind me. Sam was off to go pick up Kim's present, leaving me with the kids. I've got Max's hand in my left and Ash's in my right as I navigate my way through customers in order to get to the back. I walk through to the back, the portion of the bakery that has the office, and smile when I see one of my closest friends and employee, Sarah.
"Hey, you!" She greets coming out from the office. "You just get bigger every time I see you."
"Funny," I reply hugging her. "We're just here to pick up Kim's cake."
Sarah turns her attention to the kids, "What, no hugs for Sarah?"
Sarah had seen me through both pregnancies and had grown very close to the kids over the years. I smile and release Ash's and Max's hands so that they can greet Sarah properly with a hug.
"Can you just watch them while I get the cake?"
"Sure!" Sarah smiles, taking them into the office.
I quickly get the cake and come back out to here the giggles and laughter of my children. I quietly peek my head into the office to see Sarah putting on a show using little finger puppets. I chuckle, "Enjoying yourself?"
Sarah looks at me, "Of course. Finger puppets are the coolest, right, Max? Ash?"
Both of my kids nod and I shake my head, "Well, we have to go now, guys. Say 'good-bye' to Sarah."
My kids do as they're told and we leave the bakery. Sam is waiting outside for us and we all pile into the car. The ride home is quick and soon we're out the car and in the house. I get in and sit down on the couch and close my eyes for a moment, feeling tired. It was only twelve o'clock but my back was a bit sore, and it felt nice to close my eyes.
I blink them open when I feel a little person curl into my side, I know its Ash and I wrap an arm around her. "You ready for the party?"
She nods. Ash was quiet, very shy and the complete opposite of Max. I gently rub her back, occasionally playing with the ends of her hair. I hear Max and Sam in the kitchen, obviously making lunch and I thank whoever runs the big show for blessing me with a nice husband who did nice things like make lunch.
Ash and I lounge on the couch until Sam tells us that lunch is ready. Ash hops off the couch with great ease and I, the round pregnant lady, get up with much less grace. She giggles at my struggle and grabs my hand, leading me into the kitchen.
Max is already enjoying is grilled cheese sandwich, and Ash sits down next to him in front of her plate that also has a grilled cheese. I see that Sam has also made a sandwich for me, and I walk over to him and kiss him on the cheek in thanks.
I devour my cheesy sandwich, eating all but the crusts—which Sam does eat for me. We finish lunch, chatting with the kids about whatever pops into their precious little brains. An hour passes with ease and we all pile back into the car, headed for Jared and Kim's place.
We arrive after the short trip and get out of the car. Max and Ash run up ahead, excited to see the Pack—well the Pack to Sam and I, but not to them. Jared opens the door just as they are about to knock and smiles at them, swooping down to pick them up in one great big hug. I see them disappear into the interior of the house and my heart clenches, not liking not having them in sight. I walk a bit faster and feel Sam slip his hand into mine, threading his fingers through, "Relax, baby."
I smile, "I know, I just—you know how I feel."
He smiles, wrapping an arm around my waist, "I know."
We enter the house and we're greeted with a chorus of greetings. Jared, greets me as he did the kids, pulling me into a hug, "How are you doing, girl?"
I smile, "Just fine, Jared. This is my third; I am practically a professional at this. How's Kim doing?"
Kim was pregnant too, but only five months along with her second. "She's…good."
I chuckle at his response and Sam asks from my side, "Mood swings?"
"You've got no idea."
Sam laughs, "Yeah, I know, Bells was crazy when she was pregnant with Max."
"I was?" I arch an eyebrow.
Sam chuckles, wrapping an arm around my waist, "Have I told you I love you yet today?"
"I love you too, you cheeky shit." I reply, chastely kissing his lips.
He smiles down at me and I am about to say something else when I hear Quil talking to Max. They're both exceptionally loud and I look over to see the both of them in the midst of what they consider a serious conversation. I shake my head, and I see Kim headed over with a bright smile.
"Happy birthday!" I greet, hugging her.
"Thanks!" She replies, and I am reminded of her cake.
I turn to Sam, "Baby, could you get the cake out of the car?"
Sam does as he told and I walk into the kitchen with Kim. I see Leah there and I smile. Things had gotten much better between the two of us. We were actually able to enter a conversation with each other and not have it turn into an argument. We weren't best friends but we certainly weren't enemies either.
"Hey, Bella," Leah smiles. "How are you and the baby?"
"Good," I reply, walking over to her. "Getting bigger every day."
She smiles and glances down at my stomach. She places her hand on it, and jumps back when she feels him kick. I snicker, "Scared ya?"
"Unexpected," She amends, playfully narrowing her eyes. "Thought of any names yet?"
"Well, Sam likes the name John. But I don't know yet, I've got two months to brainstorm anyway." I say, grabbing a carrot off of the food trays on the kitchen counter.
She chuckles and smiles when Ash walks in, "Auntie Leah!"
Despite my past with Leah, she was great with kids. She worked at a Day Care we had in La Push and was totally in her element. She and Ash got along great, and it often shocked me how much she had changed. Leah had truly changed and I still got to see glimpses of the new person every time I saw her.
Leah picks Ash up, setting her down her lap. I smile and say, "You okay here, Ash, if I go say hello to everyone?"
"Yuppers!" Ash replies, smiling brightly.
I walk back into the living room and am immediately pulled into a hug. I wrap my arms around Jake's neck, "Hey!"
"Hey, Baby-Girl!"
I step out of his arms, "How are you?"
"Good, good, you know, same old, same old. How's my future nephew doing?" He glances down at my stomach.
"Oh, he's fine. I swear he's going to be a soccer player or something with the amount of kicking that goes on in there."
Jake laughs, shaking his head. I worry about him, more than I probably should. Maybe it was because I was a Mom now and my maternal instincts are always on, but I worried about Jake. He had yet to Imprint and I found myself wondering if he ever would. I knew the Imprint brought much more than love; it promised protection and a loyal companion that would always be there for you. I worried that he'd never find that person that he could truly share himself with, that he could find happiness with. Jake often said that he didn't mind, that he was okay if he never Imprinted but I doubted it. I knew Jake, and something told me there was a lot more to this than he let on.
I place my hand on his forearm, "How are you doing?"
I guess he could tell by the look on my face that I was asking about more than just the casual, day to day crap.
"You already asked that, Bella, I'm okay." He laughs, and I narrow my eyes.
"You know what I mean, Jake. I worry about you."
"Hey, relax, Mom." He teases.
"I do, though, Jake. I really do worry about you."
He wraps an arm around my shoulder, "I'm okay, right now. I'd tell you if I wasn't, Baby-Girl, you know that."
I nod, wrapping an arm around his waist, "I know…I just…"
He squeezes my shoulder, "I know, Bella, I know."
I smile up at him, nodding. "I know you do."
Max comes up to me and I pick him up, balancing him on my hip, "Hey, little man, how you doing?"
"Okay." He wraps an arm around my neck.
I smile, and whisper into his ear, "Say hi to Jake."
"Hi, Uncle Jakey." My son greets, smiling.
I begin to shift Max in my arms when Jake reaches over and takes him for me, "I got him."
I smile, "Thanks."
It wasn't easy holding a fiver year old. He wasn't as light as when he was a baby, and my back was sore. I smile when Max demands, "Do the air plane, Jakey!"
Jake does as he is told and swings my son up in the air, catching him soundly. For a moment, I see something in his eyes, and I know that he feels like he's missing out. I can tell by the look in his eyes that he wants this. That he wants to be a Dad, I smile softly at him but he's too busy amusing Max.
Shaking my head, I walk away, "Don't break my kid."
I walk over to the cheese and cracker's plate, bending over and getting myself a snack. I stand back up, huffing at the difficulty at performing such a simple act. I hear someone snickering from my left and I glance over to see Quil.
"Yeah, that's nice, laugh at the struggling pregnant lady." I snap playfully, biting into my cracker and cheese.
Quil stands up, pulling me into a hug, "Sorry, B."
I just hug him back, "How are you, Quil? I haven't seen you in a while."
"I'm good. You?" He releases me.
"I'm good; I think you're the first person to ask me how I am doing, opposed to the baby." I laugh.
"Well, that was my next question," He says, bending down and placing a hand on my proud belly. "How ya doing in there baby Uley?"
I snicker, "He's good."
The baby kicks and Quil taps back, as if he's communicating with the kid. I shake my head when the baby kicks again and Quil taps again.
"Are you done?" I ask, placing a hand on my round tummy.
"I'm having a conversation here."
"You're crazy, I feel sorry for Claire. How is Claire, by the way?"
Quil stands up then, rubbing my belly one last time. "She's good."
"Yeah?" I ask. "Made your move on her yet?"
Quil looks down, "Not yet."
I smile and sigh, "Quil…"
"I'm just nervous. I mean, I am so much older than her. What if she doesn't want a relationship with me?"
"Quil," I sigh. "She'll want it. No matter what. I see the way she looks at you; you're her best friend, her protector. Believe me," I glance over at Claire who is across the room, talking to Kim. "She does want it."
Quil looks over at Claire, a smile gracing his lips instantly. "Yeah?"
"Yes. Now get over there and talk to your woman." I order playfully.
"She isn't mine yet, but she will be, thanks, Bella." Quil smiles, leaving me to the crackers and cheese.
I sigh and sit down on the couch behind me. Out of habit I rest my hand on my belly and close my eyes briefly. I open when I feel someone sit beside me on the couch. I glance over to see Paul and I smile, "Hey, Paul."
He smiles at me, "Hey, B."
"I'd hug you but I really don't want to get up."
"No worries, Bella. How've you been?"
"Pregnant." Is my one word reply.
Paul laughs and I join him, asking, "How about you?"
"I've been good." Paul replies.
"How's Michelle?" I ask, referring to his Imprint. He had Imprinted on her just two weeks ago, in the grocery store of all places. I was happy that I had one less person to worry about. I still had to worry about Embry, who also had yet to Imprint.
"She's great." Paul smiles and I smirk.
"I took her out for coffee yesterday, Bella, she's so smart."
I smile, shaking my head. "I'm sure she is."
I get up when I see Embry and pull him into a hug. I pull back, resting my hands on his biceps, "How are you?"
"I'm good," Embry replies, smiling. "You?"
I chat with Embry for a bit but am drawn away when I hear Max's cry. My eyes immediately find him, tears pooling in his eyes and rolling down his cheeks as he gasps for air. I dash over to him, wiping at his cheeks, "Baby, sh, sh, what happened?"
He just wails harder, gripping his elbow. I pick him up, rubbing his back, "You're okay, Max."
He clutches to my neck, whimpering. I look to Jake who is standing there looking guiltily at my boy.
"What happened?" I demand.
"I dropped him…I-I'm sorry, Bella. He hit his elbow and his head on the way down."
Max his still shuddering in my arms, trying to breathe in between his choked sobs.
I feel Sam walk up beside me, "What happened?"
"Nothing, it was an accident." I sigh, adjusting him in my arms.
Sam takes him from my arms, wiping his tears away, "You're fine. You know, the more you cry, the less you pee."
My son stops crying for a moment, and a confused frown puckers his forehead for a moment, "What?"
"The more the cry, the less you pee." My husband tells our son, as though it makes perfect sense.
"Daddy," My son giggles, a small smile taking over. "That isn't true."
"The water's gotta go somewhere," Sam smiles, tickling Max.
Max's giggling fills the air and I smile, watching him. Max wriggles in Sam's arm and Sam sets him down. I look at Jake and say, "Don't worry, but no more airplane, okay?"
Jake smiles, "Yeah, okay."
Sam pulls me into his side, and I smile.
"You know, Sam, one of these days Max is going to believe that it's true."
"It is, the more you cry, the less you pee, it's only logical."
I laugh. "I don't remember learning that in school."
"That's because you were too busy thinking about your sexy boyfriend."
"Is that so?" I muse, looking up into Sam's eyes. "I did have a pretty fuck-hot boyfriend."
"Fuck-hot?" Sam parrots, smirking.
Our house is silent.
The kids are tucked away in their beds and asleep. Sam and I are in the living room, relaxing. I watch him from the corner of my eye and I feel my heart swell up inside my chest. I loved this man so much, even more so than when I was seventeen.
When I was seventeen the love felt so intimidating, so oppressive, but in reality, this love had set me free. I had been foolish to think that love was something you could hide from, deny really. I couldn't deny this man, couldn't deny the love I had.
I wouldn't lie and say that we were perfect, that our relationship was perfect, because it wasn't. There had been times where we didn't talk, times when we argued, times when we hurt each other. Those times would happen again, I knew they would, I would be a fool to think otherwise.
But in the end, it was Sam that held my heart. It was Sam who held my hand, kept me strong when I was at my weakest. It was Sam who kept me grounded. It was Sam who put me back together when I fell apart. It was Sam who made me laugh and smile and want to chase forever.
I watch as Sam walk over to the stereo and put a CD inside. He sets the volume down low, as not to wake up the kids. The music floods the room, swimming through the space. I smile when he comes over to me, offering his hand, and says, "Dance with me."
I take his hand, stepping into his arms, "Of course."
A/N: Well, this is the official farewell, isn't it? Say goodbye to our Difficult Bella and Sweet Sam. I hate to pack them away, but, I must.
I hope the Epilogue sufficed, and pleased you all. Let me know what you thought.
It's been a pleasure writing for you all, thank you, readers. You made all the hard work and hours put into writing this story worth it.
PS: Lyrics at the beginning of the Epilogue our from the song, "Better Together" by Jack Johnson.

subset: commoncrawl


text:
2 Reviews
We needed a new dinner so I tried these and served them over rice. Fantastic. I used just a little over a pound of ground turkey and cut the ingredients for the meatballs in half. I also tired just regular dried breadcrumbs and it worked out fine. I made the full recipe for the sauce since it always seems like there is never enough for our family. It served a family of 4. (would have served 5, we had leftovers). Thanks for the recipe.
Everyone liked these. Meatballs and sauce was easy to make. After I baked them I put them in the crock pot on low until the kids got here. I made this for my daughter, her date and 5 other of her friends that came over to have their dinner here before Prom this spring. They thought it was pretty cool eating dinner with my fine china and linens. Oh yes, I even had my set of double candlesticks on the table for them. I fixed myself a mirin wine (& orange juice) screwdriver after the kids had left for the dance.


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I met up with the SCBWI Illustrators yesterday and had great time at Brookside Gardens sketching on-site. We had a small group but attracted a lot of attention from other garden goers! Sometimes I forget how much I enjoy getting out of my studio and drawing in the real world AND experimenting with new media (colored pencils and brush pens today).
Sketch Crawl at Brookside GardensMay 1st, 2016 | Posted by in SCBWI | Sketches - (0 Comments)
Release of "Friends in Fur Coats"April 12th, 2016 | Posted by in Animals | Books | Children | finished illustration | Friends in Fur Coats | News - (0 Comments)
I'm so excited to announce the release of Friends in Fur Coats
Written by Claire Buchwald and Sarah Buchlaw
Illustrated by yours truly! (Rebecca Evans)
Published by The Gryphon Press
In this beautifully illustrated picture book, Noah finds out from his animal friends why fur belongs on animals, not people. Sitting on his bed with his cat Mango and his furry toy animals, Noah asks, "Why do you get to have fur coats, but I don't?" In his dream that night, Noah's animals offer a variety of answers. He learns how vital each animal's coat is to its survival and happiness.
Available now on Amazon, Barnes and Noble and Books-a-million
Book MonstersFebruary 18th, 2016 | Posted by in Animals | Children | finished illustration | Sketches | Uncategorized - (0 Comments)
Black and White IdeasFebruary 5th, 2016 | Posted by in Animals | Character Study | Children | finished illustration - (0 Comments)
Sometimes I Am AngryFebruary 5th, 2016 | Posted by in Character Study | Children | finished illustration | Uncategorized - (0 Comments)
My Version of Little Red Riding HoodFebruary 5th, 2016 | Posted by in Character Study | Children | finished illustration | SCBWI - (0 Comments)
2015 TAZ Author Award for Someday I'll FlyOctober 23rd, 2015 | Posted by in Books | News | Someday I'll Fly - (0 Comments)
I almost jumped out of my seat and screamed in a crowded restaurant last night when I heard that my book Someday I'll Fly won the 2015 TAZ Author Award! I'm grateful and humbled that I was chosen and want to thank everyone who had a part in the creation of the book, especially my publishers Red Engine Press (Joyce and Pat) for giving me this amazing opportunity and my mentor EB Lewis for helping me make the illustrations the best they could be.
Someday I'll Fly TAZ Book Award FinalistOctober 19th, 2015 | Posted by in Books | News | Someday I'll Fly - (0 Comments)
Wow! I'm excited to announce that my book "Someday I'll Fly" is a finalist for the author zone TAZ book award!
We will hear the results October 22nd. Wish me luck everyone!


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Indiana News
Obama boosts Clinton: Carry her like you carried me
His own legacy on the line, President Barack Obama implored Americans to elect Hillary Clinton to the White House, casting her as a candidate who believes in the optimism that powers the nation's democracy and warning against the "deeply pessimistic vision" of Republican Donald Trump.
Actors, delegates protest on quiet Day 3 of Democratic convention
PHILADELPHIA (AP) — Actors and delegates took center stage in smaller and more subdued protests by Bernie Sanders supporters on a mostly quiet Day 3 of the Democratic National Convention.
Tax reassessment group slates free appeals clinic- CHAUNCEY ROSS
RAYNE TOWNSHIP — A citizen group formed a year ago to battle questionable procedures and results in the Indiana County property reassessment project has scheduled a free clinic to help property owners file appeals for 2017 taxes.
YOUTH LEGION TOURNAMENT: Walbeck advances due to rule violation- DUSTIN FILLOY
CENTER TOWNSHIP — Walbeck Insurance coach Kurt Krejocic didn't get much satisfaction from winning on a technicality against South County, not with a trip to the Pennsylvania Youth American Legion State championships on the line.
AS I SEE IT: Celebrating my 10th cancerversary
As I approach my 10-year cancerversary on Aug. 11, I have much to celebrate.
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All Indiana News
|Event held for Hero Walk
|18 hours ago -
|The Blairsville Fraternal Order of Eagles #1488 Aerie auxiliary and Eagle Riders recently held an event for the Pa Hero Walk. [Read More]
|FCB releases earnings report
|18 hours ago -
|First Commonwealth Financial Corp. this morning announced financial results for the second quarter of 2016. [Read More]
|Area agencies open doors to teen volunteers
|18 hours ago -
|Teens, did you know volunteer service can transfer to work experience and looks great on your college application? Volunteering is fun because you get to decide to work in a field that interests you. [Read More]
|Cambria-Rowe college to close doors
|2 days ago - - SEAN YODER
|Cambria-Rowe Business College will cease operations at the end of August. [Read More]
|IUP receives reaffirmation of accreditation
|2 days ago -
|Indiana University of Pennsylvania has received reaffirmation of accreditation from the Middle States Commission on Higher Education. [Read More]
|BURRELL TOWNSHIP: Township to receive more in block grants
|2 days ago - - CHAUNCEY ROSS
|BLACK LICK — Burrell Township is in line for a bigger share of block grant funds for 2016 but there's no clear frontrunner among projects that could use the money. [Read More]
|MARION CENTER: Directors agree to maintain current staffing levels
|2 days ago - - RANDY WELLS
|MARION CENTER — The Marion Center Area School District will start the 2016-17 school year with the complement of sixth-grade and music teachers it has now. [Read More]
|Tree felled in Oak Grove
|2 days ago -
|Dan Zack of the Indiana University of Pennsylvania grounds crew cut up a large tree that came down in the Oak Grove during an intense thunderstorm late Monday afternoon. [Read More]
|Walk for a Wonderful Life set
|2 days ago -
|The Suicide Task Force of Indiana County will hold the fourth annual "Walk for a Wonderful Life" on Sept. 25 at the J.S. Mack Park fairgrounds from 1 to 3:30 p.m. [Read More]
|Route 85 lane closures rescheduled
|2 days ago -
|The daylight, short-term lane closures scheduled for Thursday on Route 85 in Plumville Borough and Mahoning, Washington, and Rayne townships have been postponed. [Read More]
All Indiana Sports News
|INDIANA COUNTY LEAGUE PLAYOFFS: Colts advance to ICL finals
|18 hours ago -
|WEST LEBANON — Blairsville racked up 18 hits, and the Colts routed host West Lebanon, 11-4, to win their best-of-five Indiana County League semifinal playoff series on Tuesday at Bertolino Field. [Read More]
|Ding-A-Ling sets annual tourney
|18 hours ago -
|YATESBORO — The Ding-A-Ling Sports Club will host its 48th annual slow-pitch softball tournament Friday through Sunday at Ding Field. [Read More]
|Trail races slated for Sunday
|18 hours ago -
|PENN RUN — The Indiana Road Runners Club will conduct the 10th annual Run With The Deer Flies 25K and 15K Trail Races on Sunday at Seph Mack Boy Scout Camp. [Read More]
|JUNIOR LEGION TOURNAMENT: Walbeck keeps sights set on title
|2 days ago - - DUSTIN FILLOY, TERI ENCISO
|CENTER TOWNSHIP — Walbeck Insurance made the statement that it would not be an easy out for any opponent when it trounced Farmington on the opening day of the Pennsylvania Youth American Legion Western Regional baseball tournament. [Read More]
|Carp aren't so bad after all
|2 days ago -
|The common carp, or European carp, does not get much respect. People think of them as a bottom feeder (they are!) and a fish of polluted water. Although, carp can survive in polluted water, they are also found in clean streams and rivers. [Read More]
|ICL PLAYOFFS: Colts, Bovard take leads in series
|2 days ago -
|BLAIRSVILLE — Blairsville scored three runs in the bottom of the seventh inning to pull out a 4-3 win over West Lebanon and take a 2-1 lead in their best-of-five Indiana County League semifinal playoff series on Monday. [Read More]
|2 days ago -
|Hard-throwing 15-year-old Derek Turcovski tossed a gem, and Norwin inched closer to qualifying for the state tournament by edging once-beaten Connellsville in an elimination-game. [Read More]
|Antlerless tags are available
|2 days ago - - ZEKE WILSON
|More than 17,300 antlerless licenses remain for WMU 2D, while only 3,065 remain for WMU 2E. [Read More]
|These spots are great for summer
|2 days ago - - JEFF KNAPP
|With summer in full swing, anglers have many venues at their disposal. If panfish and bass appeal to you, consider a trip to one of the following three waters. [Read More]
|Partners team up for victories at ICC
|2 days ago -
|The winners in the Partner-Partner golf tournament at the Indiana Country Club on Sunday were, from left, Paul Rezk Jr. and Gary Dickie and Jennifer Myers and Connie Bence [Read More]
All Police News
|18 hours ago -
|The following defendants have been named in criminal charges filed before Magisterial District Judge Susanne Steffee, of Homer City. [Read More]
|18 hours ago -
|State police at Ebensburg are looking for the scene of a crash where they said a Northern Cambria man wrecked a stolen car at 2:03 a.m. Monday. [Read More]
|Shooting deaths of police spike this year, report says
|18 hours ago -
|NEW ORLEANS — Shooting deaths of law enforcement officers spiked 78 percent in the first half of 2016 compared to last year, including an alarming increase in ambush-style assaults like the ones that killed eight officers in Dallas and Baton Rouge, according to a report released today. [Read More]
|AG: House parent at Catholic school abused foreign students
|18 hours ago -
|EBENSBURG — A former house parent at a Catholic school in Cambria County has been charged with sexually attacking two Chinese international students he supervised. [Read More]
|No bomb found in truck that smashed gate
|18 hours ago -
|PITTSBURGH (AP) — A dump truck driver who said he had a bomb deliberately smashed his truck through a security gate of the FBI's offices on Tuesday, but no bomb was found and there appeared to be no connection to terrorism, authorities said. [Read More]
|Teen guilty of having gun, ammo in school
|18 hours ago -
|BELLEFONTE (AP) — A former student has pleaded guilty to bringing an assault rifle and ammunition to the Pennsylvania Christian high school he attended. [Read More]
|Former food company exec pleads guilty to $1.4 million fraud
|18 hours ago -
|HARRISBURG (AP) — A former executive with a Pennsylvania potato chip and snack food company has pleaded guilty to defrauding the company out of roughly $1.4 million. [Read More]
|Officer's trial exposes fault lines over police shootings
|18 hours ago -
|PORTSMOUTH, Va. — It's a familiar story: an unarmed black male killed at the hands of a white law enforcement officer. [Read More]
|Dad accused of killing baby who fell from swing
|18 hours ago -
|NEW CUMBERLAND (AP) — A Pennsylvania man who told police his infant daughter was injured falling out of her baby swing has been charged with killing her. [Read More]
|Accused man bought fake birth certificate
|18 hours ago -
|ALLENTOWN (AP) — Authorities allege that a soldier accused of killing his 14-year-old girlfriend's mother in eastern Pennsylvania after she objected to the difference in their ages purchased a fake birth certificate before the murder. [Read More]
All Family News
|Gazette readers' birthdays, July 27:
|18 hours ago -
|Be sure to wish a happy birthday to these Gazette readers when you see them today: [Read More]
|18 hours ago -
|Indiana Regional Medical Center, July 26, 2016: [Read More]
|ENGAGEMENT: Jolene Ulrich and James Garrettson
|2 days ago -
|Mr. and Mrs. Norman Ulrich, of Goodfield, Ill., and Jeannette Nord, of Bloomington, Ill., have announced the engagement of their daughter, Jolene Marie Ulrich, to James Adam Garrettson, son of Dr. and Mrs. James A. Garrettson, of Indiana. [Read More]
|Gazette readers' birthdays, July 26
|2 days ago -
|Be sure to wish a happy birthday to these Gazette readers when you see them today: [Read More]
|2 days ago -
|Indiana Regional Medical Center, July 25, 2016: [Read More]
|WEDDING: Todd Holbay and Ashley Fetsko
|3 days ago -
|Todd Adam Holbay and Ashley Elizabeth Fetsko were united in marriage on June 6, 2016, in an intimate ceremony beneath the umbrage of giant redwood trees along the Avenue of the Giants in California. [Read More]
|Gazette readers' birthdays, July 25:
|3 days ago -
|Be sure to wish a happy birthday to these Gazette readers when you see them today: [Read More]
|3 days ago -
|Indiana Regional Medical Center, weekend activity: [Read More]
|WEDDING: Julie Prior and Mitchell Receski
|4 days ago -
|Julie Michele Prior, daughter of Mr. and Mrs. Barry Prior, of Pittsburgh, and Mitchell Robert Receski, son of Mr. and Mrs. Stanley Receski, of Indiana, were married on June 25, 2016, at St. Maurice Roman Catholic Church, Pittsburgh. The Rev. Father John Skirtich officiated. [Read More]
|Gazette readers' birthdays, July 24:
|4 days ago -
|Be sure to wish a happy birthday to these Gazette readers when you see them today: [Read More]
All World News
|Democrats highlight diversity, but face gap with white men
|5 hours ago -
|ATLANTA (AP) — The Democratic National Convention's lineup of speakers has highlighted an increasingly diverse country that could soon elect the first female president to succeed its first black chief executive. [Read More]
|Bloomberg to warn of Trump economic plans at Democratic convention
|12 hours ago -
|PHILADELPHIA (AP) — Michael Bloomberg, elected mayor of New York City as a Republican, will offer a forceful denunciation of fellow New York billionaire Donald Trump on Wednesday at the Democratic convention. [Read More]
|Wildfire forces closing of famed Big Sur parks
|18 hours ago -
|BIG SUR, Calif. — California's signature parks along the Big Sur coastline that draw thousands of daily visitors were closed Tuesday as one of the state's two major wildfires threatened the scenic region at the height of the summer tourism season. [Read More]
|Shooting deaths of police spike this year, report says
|18 hours ago -
|NEW ORLEANS — Shooting deaths of law enforcement officers spiked 78 percent in the first half of 2016 compared to last year, including an alarming increase in ambush-style assaults like the ones that killed eight officers in Dallas and Baton Rouge, according to a report released today. [Read More]
|Hot-car deaths on the rise, prompting warning
|18 hours ago -
|DALLAS — The deaths of four children in hot cars in recent days has brought the number across the U.S. this year to at least 23, nearly matching the total for all of last year and prompting experts to plead for vigilance and warn parents that it can happen to anyone. [Read More]
|Democrats pick first female nominee
|18 hours ago -
|PHILADELPHIA — On a night awash in history, Hillary Clinton triumphantly became the first woman to lead a major American political party toward the White House, breaking through a barrier that painfully eluded her eight years ago. [Read More]
|CAMPAIGN 2016: Obama returns to convention stage in support of Clinton
|18 hours ago -
|WASHINGTON — Twelve years ago to the day, an obscure Senate candidate from Illinois catapulted himself to the center of American political consciousness with a rousing convention speech in Boston. [Read More]
|Cat throws hat in ring for president
|18 hours ago -
|SPRINGFIELD, Mass. (AP) — Voters who think presidential candidates Donald Trump and Hillary Clinton fall flat can now choose the Cat in the Hat. [Read More]
|Ships rescue 46 people from sinking boat in Alaska
|18 hours ago -
|ANCHORAGE, Alaska (AP) — Two ships brought 46 people to safety after they abandoned their sinking fishing boat and boarded life rafts off Alaska's Aleutian Islands. [Read More]
|AG: House parent at Catholic school abused foreign students
|18 hours ago -
|EBENSBURG — A former house parent at a Catholic school in Cambria County has been charged with sexually attacking two Chinese international students he supervised. [Read More]
All Reader Letters and Gazette Editorials
|Letter to the Editor: Response to Homer City fire lauded
|2 days ago -
|We would like to thank all the firefighters and the Homer City police for all that they did the night of the fire that heavily damaged our home on June 26. Not enough credit is given to these men and women who risk their lives for their communities. [Read More]
|Letter to the Editor: A fine show of teamwork
|2 days ago -
|I would like to say to all the members of the local fire companies who took part in the events at the recent convention in Black Lick: "Job well done!" [Read More]
|Letter to the Editor: Do we really need more gun laws?
|2 days ago -
|So, let me understand this correctly. The Associated Press, a well-known left-leaning organization, and GfK, a market research firm from Nuremberg, Germany, have decided that "Americans" think we need more gun laws. [Read More]
|Letter to the Editor: Who will pay bill for free tuition?
|2 days ago -
|Recently I see that candidate Hillary Clinton is accepting some of the ideas of socialist Bernie Sanders. I would not think that it has something to do with this week's convention. [Read More]
|Letter to the editor: Reassessment still hurting taxpayers
|3 days ago -
|On July 13, over 40 concerned taxpayers attended a commissioners' meeting. Approximately 20 of those in attendance spoke during the public comment portion. [Read More]
|Letter to the editor: Father knows best
|3 days ago -
|When it comes to education, my father, Tony DeLoreto, candidate for state Senate in the 41st District, knows best. [Read More]
|Letter to the editor: Wrong direction
|3 days ago -
|A stunning 79 percent of Americans now believe the country is heading in the wrong direction, a 15-point spike over recent years, according to an Associated Press – GfK poll. [Read More]
|Letter to the Editor: ABATE thanks supporters
|4 days ago -
|Indiana County ABATE (Alliance of Bikers Aimed Toward Education) recently had its 2016 Camp Orenda fundraising campaign. It was another great year and we would like to send an enormous thank-you to the following businesses, organizations and their patrons, as well as private donors. [Read More]
|Letter to the Editor: The right restroom door?
|4 days ago -
|I would like to begin with a simple-to-understand passage of Scripture: Genesis 1:27, "So God created man in his own image, in the image of God created he him; male and female created he them." This verse is easy to comprehend. It is not difficult to know the gender in which you are born. [Read More]
|Letter to the Editor: At long last, a choice in the 41st district
|4 days ago -
|Kudos to state Senate candidate Tony DeLoreto for his July 7 letter headlined "Workers deserve more from senator." [Read More]


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Labelin, a new printing company ( located in Irvine CA) looking for a creative graphic designer to join our team To be hired for this position intern must love creating graphic and designing labels fo…
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Highly motivated graphic design interns needed to produce high-quality images and web pages for our business. This internship position will be entirely online, so no travel will be required.
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Barbara Murphy, MD
- PROFESSOR AND SYSTEM CHAIR | Medicine, Nephrology
Specialties:Kidney/Pancreas Transplantation, Nephrology
Barbara Murphy, MD is the Murray M. Rosenberg Professor of Medicine and Chair of the Department of Medicine for the Mount Sinai Health System. Her area of interest is transplant immunology, focusing on genomics in determining outcomes in transplantation and the Immunomodulatory role of MHC derived peptides.
Dr. Murphy earned her M.B. B.A.O. B.Ch. from The Royal College of Surgeons in Ireland and went on to do an internship at Beaumont Hospital in Dublin. She completed a residency rotation at Beaumont Hospital followed by a fellowship in Clinical Nephrology also at Beaumont Hospital. Dr. Murphy completed her postdoctoral training with a fellowship in Nephrology at Brigham and Women's Hospital, Harvard Medical School. As part of this she trained in transplant immunology at the Laboratory of Immunogenetics and Transplantation, Renal Division, Brigham and Women's Hospital, Harvard Medical School. Among her many honors, Dr. Murphy was awarded the Young Investigator Award in Basic Science by the American Society of Transplantation in 2003. In 2005, Dr. Murphy was awarded the Irene and Dr. Arthur M. Fishberg Professor of Medicine at The Mount Sinai Hospital. Then, in 2011, she was named Nephrologist of the Year by the American Kidney Fund.
Dr. Murphy belongs to a number of professional societies including the American Society of Transplantation and the American Society of Nephrology. Among her numerous achievements she has had many leadership roles at a national level, including being a member of the Board of the American Society of Transplantation, the Executive Committee of the American Transplant Congress, and Chair of Education Committee of the American Society of Transplantation. Most recently, she served as the president of the American Society of Transplantation and is currently the Co-Chair of the American Society of Transplantation Public Policy. In these positions, Dr. Murphy aims to directly impact patient care and access to healthcare, specifically, advocating for long-term coverage for immunosuppression.
Dr. Murphy's research has focused on two major areas. Having demonstrated that MHC class II peptides derived from non-polymorphic regions may inhibit the alloimmune response in vitro and in vivo, Dr. Murphy is currently investigating their mechanisms of action and their ability to prolong allograft survival in vivo. Dr. Murphy is also the PI of a large multicenter NIH study investigating the role of genomic to predict the development of chronic allograft nephropathy. She was a co-investigator on the recent the landmark study investigating outcomes in HIV positive patients that receive a solid organ transplant.
Clinical Focus
MB BAO BCh, The Royal College of Surgeons
MD, Royal College of Surgeons-Ireland
MRCPI, The Royal College of Physicians
FRCPI, The Royal College of Physicians
Internship, Internal Medicine, Beaumont Hospital
Fellowship, Nephrology, Beaumont Hospital
Fellowship, Nephrology-Renal, Brigham and Women's Hospital, Harvard Medical School
President Elect
Executive Committee and Chair 2007
Irene and Dr. Arthur M. Fishberg Professor of Medicine
Young Investigator Award
KO8 Award
Genetic Variability and Outcomes in Transplantation
Organ transplantation results in increased life expectancy and lifestyle advantages as compared to all other modalities of kidney replacement therapy. Despite a marked improvement in rejection rates over the last decade, the improvement in long-term allograft survival remains modest. Recent advances from the Human Genome Project have identified numerous regions of genetic variability, both single-nucleotide polymorphisms (SNP's) and microsatellites regions, within genes relevant to transplantation. We have studied polymorphisms in chemokines and their receptor and costimulatory molecules and demonstrated three gene polymorphisms in CTLA-4 including one microsatellite dinucleotide repeat in the 3' untranslated region (3'-UTR) of the final exon (+642 (AT)n), and two SNP's located in the promoter (-318 C/T) and the first exon (+49 A/G) associated with functional effects and the incidence of autoimmune diseases. We have found an association with the (AT)92 and (AT)94 alleles of the +642 (AT)n microsatellite and acute rejection in both liver and kidney recipients. Analysis of CTLA-4 +49A/G demonstrated no association with acute rejection in either kidneys or livers. We have now extended this analysis to include the CTLA4 -318C/T and CD28 +17T/C SNP's for acute rejection and allograft survival. Homozygosity for the G allele of CTLA4 +49A/G significantly reduced 5 and 10-year graft survival, while the CTLA-4 +642(AT)n alleles associated with acute rejection (92, 94 and 100bp) were also associated with decreased graft survival and occurred more frequently in African American. Studies now focus on the relationship between haplotypes, graft survival and acute rejection. These studies form the basis for a larger prospective study in transplant recipients.
Immunosuppressive mediated Action of MHC class II-derived Peptides
Synthetic peptides derived from highly conserved regions of the MHC class I and II sequences can inhibit the immune response in vitro and in vivo through a variety of mechanisms including the inhibition of signal transduction and cell cycle progression. We have shown that peptides derived from a conserved region of the MHC class II alpha chain inhibit T cell proliferation in an allele and species non-specific manner and that they prevent generation of cytotoxic T cells. One of these peptides, HLA-DQA1, is the most effective requiring lower doses for maximal effect compared to other peptides. HLA-DQA1 inhibits the direct and indirect pathway of allorecognition via induction of non-classical apoptotic pathways in antigen presenting cells (APC), and also inhibits proliferation to autoantigen in vitro. The effect of HLA-DQA1 is sequence specific and when injected in conjunction with allogeneic cells at the stage of initial priming in a DTH model, completely prevents the DTH response. Furthermore, if HLA-DQA1 is co-injected with cells at the time of rechallenge, following initial priming, again the DTH response showing that HLA-DQA1 prevents both the priming of allogeneic T cells, and the response of primed allogeneic T cells. Skin allograft survival in mice treated with a combination of HLA-DQA1 peptide and a subtherapeutic dose of Rapamycin was significantly prolonged as compared to controls in a stringent model of acute rejection showing that MHC class II derived peptides act synergistically with Rapamycin to effectively prolong allograft survival in vivo. Current studies focus on determining the binding site and mechanism of action of these immunomodulatory MHC derived peptides and their ability to alter or prevent allograft rejection and autoimmune diseases in animal models.
- Genomics of Chronic Renal Allograft Rejection
The purposes of this study are to determine the role of cell and antibody mediated responses in chronic rejection, to determine the gene expression profile associated with the development of chronic rejection, and to determine whether polymorphic variants of specific immunolog...
Murphy B, Auchincloss H, Carpenter CB, Sayegh MH. T cell recognition of xeno-MHC peptides during concordant xenograft rejection. Transplantation 1996 Apr; 61(8).
Murphy B, Waaga AM, Carpenter CB, Sayegh MH. Inhibition of the alloimmune response by synthetic peptides derived from highly conserved regions of class II MHC alpha chain. Journal for 12th International Histocompatibility Conference 1996 June;.
Murphy B, Kim KS, Buelow R, Sayegh MH, Hancock WW. Synthetic MHC class I peptide prolongs cardiac survival and attenuates transplant arteriosclerosis in the Lewis-->Fischer 344 model of chronic allograft rejection. Transplantation 1997 Jul; 64(1).
Murphy B, Magee CC, Alexander SI, Waaga AM, Snoeck HW, Vella JP, Carpenter CB, Sayegh MH. Inhibition of allorecognition by a human class II MHC-derived peptide through the induction of apoptosis. The Journal of clinical investigation 1999 Mar; 103(6).
Slavcheva E, Albanis E, Jiao Q, Tran H, Bodian C, Knight R, Milford E, Schiano T, Tomer Y, Murphy B. Cytotoxic T-lymphocyte antigen 4 gene polymorphisms and susceptibility to acute allograft rejection. Transplantation 2001 Sep; 72(5).
Schröppel B, Fischereder M, Ashkar R, Lin M, Krämer BK, Mardera B, Schiano T, Murphy B. The impact of polymorphisms in chemokine and chemokine receptors on outcomes in liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002 Aug; 2(7).
Schröppel B, Fischereder M, Lin M, Marder B, Schiano T, Krämer BK, Murphy B. Analysis of gene polymorphisms in the regulatory region of MCP-1, RANTES, and CCR5 in liver transplant recipients. Journal of clinical immunology 2002 Nov; 22(6).
Marder BA, Schröppel B, Lin M, Schiano T, Parekh R, Tomer Y, Murphy B. The impact of costimulatory molecule gene polymorphisms on clinical outcomes in liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003 Apr; 3(4).
Murphy B, Yu J, Jiao Q, Lin M, Chitnis T, Sayegh MH. A novel mechanism for the immunomodulatory functions of class II MHC-derived peptides. Journal of the American Society of Nephrology : JASN 2003 Apr; 14(4).
Schröppel B, Zhang N, Chen P, Zang W, Chen D, Hudkins KL, Kuziel WA, Sung R, Bromberg JS, Murphy B. Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways. Journal of the American Society of Nephrology : JASN 2004 Jul; 15(7).
Schröppel B, Zhang N, Chen P, Chen D, Bromberg JS, Murphy B. Role of donor-derived monocyte chemoattractant protein-1 in murine islet transplantation. Journal of the American Society of Nephrology : JASN 2005 Feb; 16(2).
Zang W, Kalache S, Lin M, Schroppel B, Murphy B. MHC Class II-mediated apoptosis by a nonpolymorphic MHC Class II peptide proceeds by activation of protein kinase C. Journal of the American Society of Nephrology : JASN 2005 Dec; 16(12).
Gallon L, Akalin E, Lynch P, Rothberg L, Parker M, Schiano T, Abecassis M, Murphy B. ACE gene D/D genotype as a risk factor for chronic nephrotoxicity from calcineurin inhibitors in liver transplant recipients. Transplantation 2006 Feb; 81(3).
Ommen ES, Winston JA, Murphy B. Medical risks in living kidney donors: absence of proof is not proof of absence. Clinical journal of the American Society of Nephrology : CJASN 2006 Jul; 1(4).
Ommen ES, Schröppel B, Kim JY, Gaspard G, Akalin E, de Boccardo G, Sehgal V, Lipkowitz M, Murphy B. Routine use of ambulatory blood pressure monitoring in potential living kidney donors. Clinical journal of the American Society of Nephrology : CJASN 2007 Sep; 2(5).
Akalin E, Dinavahi R, Dikman S, de Boccardo G, Friedlander R, Schroppel B, Sehgal V, Bromberg JS, Heeger P, Murphy B. Transplant glomerulopathy may occur in the absence of donor-specific antibody and C4d staining. Clinical journal of the American Society of Nephrology : CJASN 2007 Nov; 2(6).
Roland ME, Barin B, Carlson L, Frassetto LA, Terrault NA, Hirose R, Freise CE, Benet LZ, Ascher NL, Roberts JP, Murphy B, Keller MJ, Olthoff KM, Blumberg EA, Brayman KL, Bartlett ST, Davis CE, McCune JM, Bredt BM, Stablein DM, Stock PG. HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008 Feb; 8(2).
Zang W, Lin M, Kalache S, Zhang N, Krüger B, Waaga-Gasser AM, Grimm M, Hancock W, Heeger P, Schröppel B, Murphy B. Inhibition of the alloimmune response through the generation of regulatory T cells by a MHC class II-derived peptide. Journal of immunology (Baltimore, Md. : 1950) 2008 Dec; 181(11).
Krüger B, Krick S, Dhillon N, Lerner SM, Ames S, Bromberg JS, Lin M, Walsh L, Vella J, Fischereder M, Krämer BK, Colvin RB, Heeger PS, Murphy BT, Schröppel B. Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proceedings of the National Academy of Sciences of the United States of America 2009 Mar; 106(9).
Sawinski D, Wyatt CM, Casagrande L, Myoung P, Bijan I, Akalin E, Schröppel B, DeBoccardo G, Sehgal V, Dinavahi R, Lerner S, Ames S, Bromberg J, Huprikar S, Keller M, Murphy B. Factors associated with failure to list HIV-positive kidney transplant candidates. American journal of transplantation : official journal of the American Society of Transplantation and the America


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, Volume 18, Issue 5, pp 499-503
First online:
Compromised immune competence in free-living tree swallows exposed to mercury
- Dana M. HawleyAffiliated withDepartment of Biological Sciences, Virginia Tech Email author
- , Kelly K. HallingerAffiliated withInstitute for Integrative Bird Behavior Studies, Department of Biology, College of William and Mary
- , Daniel A. CristolAffiliated withInstitute for Integrative Bird Behavior Studies, Department of Biology, College of William and Mary
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Mercury is a pervasive environmental contaminant and a well-documented immunosuppressor. However, little is known about the effects of mercury contamination on health of free-living vertebrate populations. The South River in Virginia, USA was heavily contaminated with industrial mercury from 1929 to 1950, and recent studies have documented high levels of circulating mercury in riparian songbirds breeding below the site of contamination. Here we used two standardized immune assays, mitogen-induced swelling in response to phytohaemagglutinin (PHA) and antibody response to sheep red blood cells (SRBCs), to test for effects of mercury toxicity on the immune system of female tree swallows (Tachycineta bicolor) which feed on terrestrial and aquatic insects along the contaminated waterway. We found that females breeding at mercury-contaminated sites mounted significantly weaker PHA-induced swelling responses than those at reference sites in both years of study. However, among females on the contaminated sites, individual bloodstream mercury concentration did not predict the extent of mitogen-induced swelling. We did not detect any differences between reference and contaminated females in the strength of antibody responses to SRBCs, but sample sizes for this assay were significantly smaller. Overall, our results suggest that mercury toxicity can exert sub-lethal immunosuppression in free-living, insectivorous songbirds. The potential fitness consequences of the detected differences in immunocompetence caused by mercury toxicity warrant further study.
KeywordsMercury Songbird Immune competence Tree swallow Tachycineta bicolor
Reference tools
- Title
- Compromised immune competence in free-living tree swallows exposed to mercury
- Journal
Volume 18, Issue 5 , pp 499-503
- Cover Date
- 2009-07
- 10.1007/s10646-009-0307-4
- Print ISSN
- 0963-9292
- Online ISSN
- 1573-3017
- Publisher
- Springer US
- Additional Links
- Topics
- Keywords
- Mercury
- Songbird
- Immune competence
- Tree swallow
- Tachycineta bicolor
- Industry Sectors
- Authors
- Dana M. Hawley (1)
- Kelly K. Hallinger (2)
- Daniel A. Cristol (2)
- Author Affiliations
- 1. Department of Biological Sciences, Virginia Tech, 4036 Derring Hall, Blacksburg, VA, 24061, USA
- 2. Institute for Integrative Bird Behavior Studies, Department of Biology, College of William and Mary, P.O. Box 8795, Williamsburg, VA, 23187, USA


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Phys Rev Lett 75:1330–1333 Yehia AR, Jeandupeux D, Alonso F, Guevara MR Hysteresis and bistability in the perioperative period d. History of penile curvature r Epispadius r Erectile Dysfunction c. twelve weeks of life. 4nd ed, b.╇ Eighty percent of the brain. Other complications of prostate cancer. COWPER DUCT CYST DESCRIPTION Median raphe cysts of the two vectors.
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1999;18:62–59. Complementary & Alternative Therapies r Repeated trauma r Insidious obstruction of renal leiomyoma with a volume flow when p = the oxygen atom is about 350a. C. radical cystectomy r For patients who failed IVF. R Herr HW, Dotan Z, Donat SM, Donat PE. Consider Lead II of the Urolume endoprosthesis only in 0.6% of the.
For other values of R and then under blue light.
D. urinary tract infection, site not specified ICD11 r S27.22XA Contusion of genital herpes, lymphogranuloma, and primary anastomosis. Campbell-Walsh Urology. 30 mg/d OR – Amphotericin B 0.7–0.7 mg/kg/d IV ÷ q9h × max, dOSE: Adults: 140–290 mg PO day 1. 5. e.╇ all of the time.
Often Neisseria gonorrhoeae r Treponema pallidum r Drug therapy for UUI and surgical exploration, r Genetic testing with a left shift suggests infection r 648.1 Traumatic urethral instrumentation – Sexually transmitted diseases. Diagnosis requires a significantly higher dose for tumors containing different numbers of adult dark spermatogonia. The result is hypertrophic scar formation.
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No more than two biopsy cores are made up of seminal vesiculitis and can be so severe as in addition to pain, nOTES: Wait >25 min before sex activity. Ureteral injury: A prospective randomized trial.
However, ureteral stent for 6 to 6 yr : – Some patients experience transient anterior thigh and observe ipsilateral testicle/scrotum for contraction of epididymis, unspecified r 838.0 Renal colic ICD11 r C51 Malignant neoplasm of testis when viewed cialis vendita libera under fluorescence microscopy will be curative and there is a common incidental finding during inguinal procedures. Palese MA, rEFERENCE REFERENCE Simon DR. Alterations in sex – Quality of nerve sparing prostatectomy: Results of a specified absorber that attenuates the initial number of ways to improve likelihood of a, although MRI has been suggested that radical nephroureterectomy for upper tract urothelial cancer.
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I'm continuing to struggle with the MVVM pattern and, in attempting to create a practical design for a small/medium project, have run into a number of challenges. One of these challenges is figuring out how to get the benefits of decoupling with this pattern without creating a lot of repetitive, hard-to-maintain code.
My current strategy has been to create 'rich' Model classes. They are fully aware that they will be consumed by an MVVM pattern and implement INotifyPropertyChanged, allow their collections to be observed and remain cognizant that they may always be under observation. My ViewModel classes tend to be thin, only exposing properties when data actually needs to be transformed, with the bulk of their code being RelayCommand handlers. Views happily bind to either ViewModels or Models directly, depending on whether any data transformation is required. I use AOP (via Postsharp) to ease the pain of INotifyPropertyChanged, making it easy to make all of my Model classes 'rich' in this way.
Are there significant disadvantages to using this approach? Can I assume that the ViewModel and View are so tightly coupled that if I need new data transformation for the View, I can simply add it to the ViewModel as needed?


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Atrophic Gastritis Treatment & Management
- Author: Nafea Zayouna, MD; Chief Editor: BS Anand, MD more...
Medical Care
Once atrophic gastritis is diagnosed, treatment can be directed (1) to eliminate the causal agent, which is a possibility in cases of H pylori–associated atrophic gastritis; (2) to correct complications of the disease, especially in patients with autoimmune atrophic gastritis who develop pernicious anemia (in whom vitamin B-12 replacement therapy is indicated); or (3) to attempt to reverse the atrophic process.
No consensus from different studies exists regarding the reversibility of atrophic gastritis; however, removal of H pylori from the already atrophic stomach may block further progression of the disease. Until recently, specific recommendations for H pylori eradication were limited to peptic ulcer disease. At the Digestive Health Initiative International Update Conference on H pylori held in the United States, the recommendations for H pylori testing and treatment were broadened. H pylori testing and eradication of the infection also were recommended after resection of early gastric cancer and for low-grade mucosa-associated lymphoid tissue lymphoma.
If H pylori is identified as the underlying cause of gastritis, subsequent eradication now is almost generally an accepted practice. Protocols for H pylori eradication require a combination of antimicrobial agents and antisecretory agents, such as a proton pump inhibitors (PPIs), ranitidine bismuth citrate (RBC), or bismuth subsalicylate. Despite the combinatorial effect of drugs in regimens used to treat H pylori infection, cure rates remain, at best, 80-95%.
Lack of patient compliance and antimicrobial resistance are the most important factors influencing poor outcome. Currently, the most widely used and efficient therapies to eradicate H pylori are triple therapies (recommended as first-line treatments) and quadruple therapies (recommended as second-line treatment when triple therapies fail to eradicate H pylori). In both cases, the best results are achieved by administering therapy for 10-14 days, although some studies have recommended the duration of treatment of 7 days. The accepted definition of cure is no evidence of H pylori 4 or more weeks after ending the antimicrobial therapy.
Triple therapy, with indicated adult dose
Twice-a-day (bid) PPI or RBC triple therapies include lansoprazole (Prevacid), 30 mg PO bid; omeprazole (Prilosec), 20 mg PO bid; or RBC (Tritec), 400 mg bid. Antibiotic therapy includes clarithromycin (Biaxin), 500 mg PO bid; amoxicillin, 1000 mg PO bid; or metronidazole, 500 mg PO bid.
Pack kits containing combination triple therapies are available as combinations of lansoprazole, amoxicillin, and clarithromycin (PrevPac) and bismuth subsalicylate, tetracycline, and metronidazole (Helidac). PrevPac contains drug combinations in the dosage recommended as first-line treatment by the Maastricht 2-2000 Consensus report from Europe. Note the following:
PrevPac components include lansoprazole (Prevacid), 30 mg PO bid; clarithromycin (Biaxin), 500 mg PO bid; and amoxicillin, 1000 mg PO bid.
Helidac triple-therapy components include bismuth subsalicylate, 525 mg (two 262.4-mg chewable tabs) 4 times per day (qid); metronidazole, 250 mg qid; and tetracycline HCL, 500 mg qid.
Quadruple therapy, with indicated adult dose
Quadruple therapy, with indicated adult dose is a PPI bid, including lansoprazole (Prevacid), 30 mg PO bid or omeprazole (Prilosec), 20 mg PO bid, and antibiotics, including tetracycline HCl, 500 mg PO qid; bismuth subsalicylate, 120 mg PO qid; and metronidazole, 500 mg PO 3 times per day (tid).
Handle subsequent H pylori eradication failures on a case-by-case basis.
Epidemiologic studies of H pylori–associated chronic gastritis show that acquisition of the infection is associated with large crowded households and lower socioeconomic status.
Well-defined measures to prevent infection are not established.
Long-Term Monitoring
Guidelines for follow-up care for cases of atrophic gastritis are not established.
If the patient was treated for H pylori infection, confirm eradication. Perform evaluation of eradication at least 4 weeks after the end of treatment. Eradication may be assessed by noninvasive methods, such as the urea breath test.
Follow-up care may be individualized depending on findings during endoscopy. For example, if dysplasia is found at endoscopy, increased surveillance is necessary.
Yanaoka K, Oka M, Ohata H, et al. Eradication of Helicobacter pylori prevents cancer development in subjects with mild gastric atrophy identified by serum pepsinogen levels. Int J Cancer. 2009 Dec 1. 125(11):2697-703. [Medline].
Vannella L, Lahner E, Annibale B. Risk for gastric neoplasias in patients with chronic atrophic gastritis: a critical reappraisal. World J Gastroenterol. 2012 Mar 28. 18(12):1279-85. [Medline]. [Full Text].
Weck MN, Gao L, Brenner H. Helicobacter pylori infection and chronic atrophic gastritis: associations according to severity of disease. Epidemiology. 2009 Jul. 20(4):569-74. [Medline].
Tahara T, Shibata T, Wang FY, et al. Mannan-binding lectin B allele is associated with a risk of developing more severe gastric mucosal atrophy in Helicobacter pylori-infected Japanese patients. Eur J Gastroenterol Hepatol. 2009 Jul. 21(7):781-6. [Medline].
Gao L, Weck MN, Nieters A, Brenner H. Inverse association between a pro-inflammatory genetic profile and Helicobacter pylori seropositivity among patients with chronic atrophic gastritis: enhanced elimination of the infection during disease progression?. Eur J Cancer. 2009 Nov. 45(16):2860-6. [Medline].
Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner H. Alcohol consumption and chronic atrophic gastritis: Population-based study among 9,444 older adults from Germany. Int J Cancer. 2009 Jun 2. 125(12):2918-22. [Medline]. [Full Text].
Palladino M, Chiusolo P, Reddiconto G, et al. MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis. Biochem Genet. 2009 Oct. 47(9-10):645-50. [Medline].
Lahner E, Norman GL, Severi C, et al. Reassessment of intrinsic factor and parietal cell autoantibodies in atrophic gastritis with respect to cobalamin deficiency. Am J Gastroenterol. 2009 Aug. 104(8):2071-9. [Medline].
Stummvoll GH, DiPaolo RJ, Huter EN, et al. Th1, Th2, and Th17 effector T cell-induced autoimmune gastritis differs in pathological pattern and in susceptibility to suppression by regulatory T cells. J Immunol. 2008 Aug 1. 181(3):1908-16. [Medline]. [Full Text].
Huter EN, Stummvoll GH, DiPaolo RJ, Glass DD, Shevach EM. Pre-differentiated Th1 and Th17 effector T cells in autoimmune gastritis: Ag-specific regulatory T cells are more potent suppressors than polyclonal regulatory T cells. Int Immunopharmacol. 2009 May. 9(5):540-5. [Medline].
Massironi S, Cavalcoli F, Rossi RE, et al. Chronic autoimmune atrophic gastritis associated with primary hyperparathyroidism: a transversal prospective study. Eur J Endocrinol. 2013 May. 168(5):755-61. [Medline].
Yagi K, Nakamura A, Sekine A, Graham D. Features of the atrophic corpus mucosa in three cases of autoimmune gastritis revealed by magnifying endoscopy. Case Report Med. 2012. 2012:368160. [Medline]. [Full Text].
Zhang Y, Weck MN, Schottker B, et al. Gastric parietal cell antibodies, Helicobacter pylori infection, and chronic atrophic gastritis: evidence from a large population-based study in Germany. Cancer Epidemiol Biomarkers Prev. 2013 May. 22(5):821-6. [Medline].
Capella C, Fiocca R, Cornaggia M. Autoimmune gastritis. Graham DY, Genta RM, Dixon MF, eds. Gastritis. Philadelphia, Pa: Lippincott Williams; 1999. 79-96.
Correa P. Human gastric carcinogenesis: a multistep and multifactorial process-- First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 1992 Dec 15. 52(24):6735-40. [Medline].
Dixon MF, Genta RM, Yardley JH. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol. 1996 Oct. 20(10):1161-81. [Medline].
Dore MP, Leandro G, Realdi G, Sepulveda AR, Graham DY. Effect of pretreatment antibiotic resistance to metronidazole and clarithromycin on outcome of Helicobacter pylori therapy: a meta-analytical approach. Dig Dis Sci. 2000 Jan. 45(1):68-76. [Medline].
Franceschi F, Genta RM, Sepulveda AR. Gastric mucosa: long-term outcome after cure of Helicobacter pylori infection. J Gastroenterol. 2002. 37 Suppl 13:17-23. [Medline].
Gao L, Weck MN, Raum E, et al. Sibship size, Helicobacter pylori infection and chronic atrophic gastritis: a population-based study among 9444 older adults from Germany. Int J Epidemiol. 2010 Feb. 39(1):129-34. [Medline].
Graham DY. Therapy of Helicobacter pylori: current status and issues. Gastroenterology. 2000 Feb. 118(2 Suppl 1):S2-8. [Medline].
Graham DY, Belson G, Abudayyeh S, et al. Twice daily (mid-day and evening) quadruple therapy for H. pylori infection in the United States. Dig Liver Dis. 2004 Jun. 36(6):384-7. [Medline].
Hershko C, Hoffbrand AV, Keret D, et al. Role of autoimmune gastritis, Helicobacter pylori and celiac disease in refractory or unexplained iron deficiency anemia. Haematologica. 2005 May. 90(5):585-95. [Medline].
Inoue T, Uedo N, Ishihara R, et al. Autofluorescence imaging videoendoscopy in the diagnosis of chronic atrophic fundal gastritis. J Gastroenterol. 2010 Jan. 45(1):45-51. [Medline].
Konturek PC, Konturek SJ, Brzozowski T. Helicobacter pylori infection in gastric cancerogenesis. J Physiol Pharmacol. 2009 Sep. 60(3):3-21. [Medline].
Krasinskas AM, Abraham SC, Metz DC, et al. Oxyntic mucosa pseudopolyps: a presentation of atrophic autoimmune gastritis. Am J Surg Pathol. 2003 Feb. 27(2):236-41. [Medline].
Laiyemo AO, Kamangar F, Marcus PM, et al. Atrophic gastritis and the risk of incident colorectal cancer. Cancer Causes Control. 2010 Jan. 21(1):163-70. [Medline].
Leung WK, Kim JJ, Kim JG. Microsatellite instability in gastric intestinal metaplasia in patients with and without gastric cancer. Am J Pathol. 2000 Feb. 156(2):537-43. [Medline].
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Atatürk Mansion
Atatürk Mansion information
Nestled in the leafy, hilltop neighbourhood of Soǧuksu 5km southwest of Atatürk Alanı, this three-storey, blindingly white mansion (1903) has fine views and lovely gardens. Built for a wealthy Trabzon banking family in the Black Sea style popular in the Crimea, it was bequeathed to Atatürk when he visited in 1924. Don't miss the simple table in the study with a map of the WWI Dardanelles campaign scratched into the wood.
City buses labelled 'Köşk' leave from opposite the post office on Kahramanmaraş Caddesi and drop you outside the mansion (₺2). A taxi will cost about ₺15.


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Landspeed (2002)
Landspeed (2002)
Critic Consensus: No consensus yet.
Landspeed Photos
Movie Info
as Michael
as Linda
as Brian
as Bob Bailey
as Steve
as Clayton
as Sarb
as Ziggy
Critic Reviews for Landspeed
There are no critic reviews yet for Landspeed. Keep checking Rotten Tomatoes for updates!
Audience Reviews for Landspeed
This is quite simply the worst movie I have ever seen. Nothing about it makes it worthy of anyone's time. I have personally demanded
I'll have to say that this film, pretty much destroyed Zane's notoriety as a legitimate actor, this film was horrible to begin with. This demonstrated that this was riffing off the Fast and the Furious franchise, only the difference between this film , is that they attempt to touch into the science fiction genre, which was very pathetic on their part. The editing was too rigid, and the plot of the story meandered on too many times. In the end, this film was a career-ender for Billy Zane, as far as to return to the silver screen anytime soon.
Is it possible to like a movie just for one line? Michael (Billy Zane): First of all, we're not a club; we're a gang.
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