text:
40 CFR 35.929-3 - Implementation of the user charge system.
(a) When a grantee's user charge system is approved, implementation of the approved system shall become a condition of the grant.
(b) The grantee shall maintain such records as are necessary to document compliance with these regulations.
(c) Appendix B to this subpart contains guidelines with illustrative examples of acceptable user charge systems.
(d) The Regional Administrator may review, no more often than annually, a grantee's user charge system to assure that it continues to meet the requirements of §§ 35.929-1 through 35.929-3.
Beta! The text on the eCFR tab represents the unofficial eCFR text at ecfr.gov.
This section's status may have changed. It may have been renumbered, reserved, or removed.
Title 40 published on 2015-07-01
The following are ALL rules, proposed rules, and notices (chronologically) published in the Federal Register relating to 40 CFR Part 35 after this date.


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In my past couple of blog entries, I wrote about some protection mechanisms for keeping the local administrator account safe on Windows systems. There are many reasons for wanting to keep the admin account safe. Some IT shops may say their primary reason is prevention against an attacker spreading further throughout the network, while others are more concerned about users elevating their privileges and modifying their systems, which introduces so many additional problems.
From a security perspective, I lean toward the former explanation, but the latter is also valid. I've seen all too often during penetration tests that we've performed that as soon as we get a local administrator on one system, all other systems fall, and we're minutes from domain admin. From there, we can pillage all we want in order to find the necessary information to take control of the network infrastructure, Unix environment, virtualization environment, etc.
While having unique passwords for the local administrator accounts on the Windows (and Unix) systems won't stop an experienced attacker, it will slow them down. That slowdown will hopefully be enough to cause the attacker to make a mistake, trigger antivirus, or generate a log event that allows you to detect him.
The following is a sampling of products that can assist in creating unique passwords for the local administrator accounts in a Microsoft Windows environment. Some of the commercial offerings are cross-platform and can also handle Unix-based systems, network devices, and more. For now, I'm more focused on the Windows side of things.
This is a list of some of the many commercial solutions I've come across as I've researched the topic for clients. Many "privileged identity management" solutions are available on the market that can manage local admin accounts.
This is a list of free and/or open-source applications and scripts that do everything from remotely change passwords on a list of systems to create random passwords via group policies. My "roots" are in a large university environment, so I like free and open-source tools, but you get what you pay for, so be careful with some of these.
Initially, I wasn't a fan of randomizing local passwords to something you don't know, but the more I thought about it over time, I realized that it doesn't matter. Obviously, if the system is part of a domain, then you should be able to do anything you need to remotely connect over the network. If, for some reason, there is a problem and the system cannot connect to the network, then there are plenty of tools out there that will let you boot the system and modify or bypass the local admin password so that you can get in.
If you have any practical experience with any of the tools above, please leave a comment or send me an e-mail. I've had clients implement several of the commercial solutions, but none of the free options. I'd be interested to hear how they've worked out.
John Sawyer is a Senior Security Analyst with InGuardians, Inc. The views and opinions expressed in this blog are his own and do not represent those of his employer. He can be reached at [email protected] and found on Twitter @johnhsawyer.
The cybersecurity profession struggles to retain women (figures range from 10 to 20 percent). It's particularly worrisome for an industry with a rapidly growing number of vacant positions.
So why does the shortage of women continue to be worse in security than in other IT sectors? How can men in infosec be better allies for women; and how can women be better allies for one another? What is the industry doing to fix the problem -- what's working, and what isn't?
Is this really a problem at all? Are the low numbers simply an indication that women do not want to be in cybersecurity, and is it possible that more women will never want to be in cybersecurity? How many women would we need to see in the industry to declare success?
Join Dark Reading senior editor Sara Peters and guests Angela Knox of Cloudmark, Barrett Sellers of Arbor Networks, Regina Wallace-Jones of Facebook, Steve Christey Coley of MITRE, and Chris Roosenraad of M3AAWG on Wednesday, July 13 at 1 p.m. Eastern Time to discuss all this and more.

subset: commoncrawl


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Braunschweig's collection of historical musical instruments is internationally renowned.
Originally opened back in 1962, shortly after the Berlin Wall was built, the museum at the legendary Checkpoint Charlie traces the history of the divided Germany and is one of the city's most popular visitor attractions.
The Gutenberg Museum, an exhibition devoted to the history of printing, offers an insight into the world of the printing press invented by Johannes Gutenberg in Mainz.
The Chocolate Museum has approximately 2,000 exhibits, making it a memorable experience for anyone with a sweet tooth.
VW's 'transparent factory', designed by Munich architectural firm Gunther Henn, represents a new era in automotive manufacturing, a pioneering production plant – smooth, clean and transparent.
See, hear, feel and experience mobility. A car collection point and themed attraction unlike any other in the world, BMW Welt brings this prestigious brand to life.
Stuttgart is home to two of the leading names in the automotive world, Daimler-Benz and Porsche – both of which have erected spectacular museums in the city.
The German Emigration Center, which received the European Museum of the Year Award in 2007, traces the history of the more than seven million people who emigrated overseas from Bremerhaven.
Discover Destination Germany with our interactive map
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"Mistakes? Writing a wrong number or name on a tax form is a mistake. Sending agents with the power to violate a person's or group's privacy is harassment at best, out-and-out criminal use of intimidation at worst," said political strategist Mike Bakker on Friday.
Share the post "IRS Inspector General's Report Small Comfort for Tea Party Groups"


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Circus classes, camps, performances, parties, and more for kids and adults in Ithaca, NY!
We're talking aerial fabric, trapeze, juggling, tight wire, acrobatics, hooping, props, and more!
Summer Session runs June 19 - Sept 2nd
We know that the summer is full of adventure... so all classes for the next few months are "drop-in" which means you do not have to commit to a 6 or 12 week session.
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A Re-Purposed Circus is coming to town!
July 20th and 21st 2016
The show One Man's Trash, a repurposed circus will be making a stop in Ithaca! Their show This circus show turns trash into treasure with an explosion of juggling and tumbling; dive into the dumpsters to see how the artists recycle, reuse, and reinvent rubbish into a circus extravaganza. Cirque Us, a new circus company, and will present this new and innovative circus show here at Circus Culture on July 20th and 21st! This new performance company is made up of some of the most promising young circus artists in the US - many of whom are graduates of the Circus Smirkus Big Top Tour- a professional touring circus made up of kids and teens.
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Entries in 'curve digital' (21)
Is the indie games scene doomed?
There have never been more indie games on the market.
Curve's new business development manager will be signing indie games at Interface next week
Rising games publisher Curve has recruited John Vega as its new business development manager.
Are we charging enough for indie games?
Since 2012 we have been spoilt with a near-constant stream of indie titles coming to digital store fronts.
'We should be charging more for indie games'
The games industry is undervaluing indie games, say leading publishers.
Could Curve become Britain's next Eidos?
Dominic Wheatley has a point to prove.
Curve Digital: We could make a cracking James Bond tie-in game
Curve Digital Entertainment boss Dominic Wheatley says movie licences could be a huge opportunity for smaller publishers.
New-look Curve eyes more acquisitions in bid to rejuvenate UK publishing scene
The new owner of UK publisher Curve says it is 'absolutely' open to further mergers and acquisitions.
Curve Digital joins Interface line-up, seeks developer partners
Curve Digital has joined the line-up of games publishers looking to meet with indie developers at this week's Interface event.
Sega, Curve and Ripstone back Digital Counts campaign
The first publishers have added their support to MCV's call for more digital download data.
Funktronic Labs on getting the Funk out of triple-A
Funktronic Labs started life in 2013.
Former Q-Games devs releasing new title Nova-111 this August
Curve Digital is publishing a new game from former Q-Games devs Eddie Lee and Kalin entitled Nova-111.
Do indie developers still need publishers?
Finally, thanks to digital distribution, developers can ditch those creatively restrictive publishers and go it alone. MCV speaks to those companies who insist the right publisher can be a force ...
Curve Digital unveils game bundling initiative
Independent game publisher Curve Digital has revealed its new game bundling service: The Indie Mixtape.
Stealth Inc 2 is exclusive to Humble Bundle on PC
Curve Digital is releasing its next PC game exclusively on the Humble Store for a limited time.
Curve Digital co-owner forms new studio Onebitbeyond
Curve Digital's co-owner and design director Jonathan Biddle has left the indie publisher to open up his own development studio.
Nintendo's new cross-buy appears to be freely dishing out copies of OlliOlli on 3DS
The new cross-buy offer that accompanied the launch of OlliOlli on Wii U and 3DS last week appears to be far more generous than anyone would have expected.
OlliOlli 2: Welcome to Olliwood lands on PS4 and Vita next week
OlliOlli 2 will launch on PS4 and PS Vita next week in North America and Europe.
Simon Byron joins Curve Digital as publishing director
Premier PR's Simon Byron is leaving the company to make the jump into publishing.
OlliOlli heading to Xbox One, Wii U and 3DS next year
Hit skateboarding game OlliOlli will make its way to a trio of new platforms sometime early next year, developer Roll 7 has announced.
VIDEO: Thomas Was Alone also jumping to Xbox One and Wii U
Mike Bithell's Thomas Was Alone is to add two additional formats to its stable of platforms.
Wii U gets a new third party exclusive title
Well, this isn't something that happens every day – Nintendo has signed an exclusive third party title for Wii U.


text: Listener Comment Line - Week of July 29, 2013 ShareTwitter Facebook Google+ Email Listen Listening... / 2:09 Fracking, national security and other issues are discussed in highlights from this week's Listener Comment Line. The comment line is a toll free call, 24 hours a day. 1-800-695-9170. Related Program: Midday MagazineTags: WAMC Listener Comment LineView the discussion thread.


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Fostering sustainable mobility is regarded as a major goal for the future development of cities. The advanced traveller information systems (ATISs), such as multi-modal route planners are envisioned as tools for enhancing more environment-friendly mobility behaviour. The authors' recent study that comprises methods of action research and Delphi forecasting, not only evaluates the actual effectiveness, but also the future expectations with regards to ATIS. Therefore the trans-disciplinary research project 'ITSworks' examined users' and experts' perspectives by working within the example of a multi-modal route planner called 'AnachB' set-up for the city area of Vienna (Austria). Within a 'Test-setting' 38 users tested the systems for several weeks, whereas 31 international experts discussed the potential of ATISs for promoting sustainable mobility in general.
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1. March from Camp Buckner - Approximately 12 miles
2. March from the Ski Slope - Approximately 2 miles
Poop Sheet FAQ and Schedule of Events 2016 as of 27 June
Registration closes 22 July: There are no slots avaialble for the march from Camp Buckner.
Grad March Back Survival Guide 2016
POC is Vince McDermott
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The AuthorsChris Rowan
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IT'S all-change at the top of the Oxford Summer League Group A table with Masons moving to the summit after beating Didcot Conservative Club 4-2, writes PETE EWINS.
Martyn Wood (4,550) and Alan Lowe, who narrowly edged past Sue Atkins 3,690-3,500, put hosts Masons 2-0 in front.
Didcot fought back to level at 2-2 thanks to wins from Dave Tooke, over Mick Murphy, and Jenny Florey, who beat Wood.
However, Lowe and Murphy won their final matches to give Masons victory.
Berinsfield beat West Oxford Democrats Club 51/2-1/2, with wins from Geoff Mace (7,240 & 4,470), Craig Mace (9,400 & 4,260) and Phil McFarland (4,920).
Eddie Tebby won half a point for Democrats after drawing with McFarland in the last game.
Marlborough Club B are the new leaders of Group B after defeating Gladiators A 5-1 at home.
Marlborough's A side climbed into second after a 5-1 win at Gladiators B.
Tonight's Matches
Didcot Con Club v Berinsfield, Democrats v Vikings, Marlborough A v Marlborough B, Gladiators A v Bletchington.
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- CRICKET: Ian Caunce's century inspires Oxfordshire Over 60s to victory
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- CRICKET: Oxfordshire Under 14s edged out in thriller
- SWIMMING: City of Oxford clean up at three-day gala
- ICE SKATING: Oxford skaters waltz off with medals at national championships


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Disposableby The Deviants
Plenty of psychedelic groups of the late '60s embraced a sunny outlook of peace, flowers, and consciousness expansion, but some took a harder line on upending the straight society they sought to replace, and like their spiritual brethren the MC5, the Deviants (under the first-among-equals leadership of writer Mick Farren) saw their music as a vehicle for a Total Assault On The Culture. The only trouble with this was the Deviants' ideas were often a lot more exciting than their music, and while they created a sonic approximation of the rage and defiance behind the Freak Culture on their debut album, Ptooff!, their second LP, Disposable, lacks focus or direction and sounds like the work of addled would-be revolutionaries who aren't sure jut what they're fighting against this morning. Farren has claimed that he and his bandmates were flying on speed during most of the recording of Disposable, but there isn't much energy (artificial or otherwise) in these performances, and many of the tunes collapse into meandering jams performed by musicians who lack the chops or focus to make them into anything more. There are a few exceptions -- a wacky mutation of "Surfing Bird" and "Wipe Out" called "Pappa-Oo-Mao-Mao," the defiant "Slum Lord," and "Somewhere to Go," the only extended jam on the LP that manages to actually find a groove and move. But "Normality Jam" feels at least twice as long as its 4:24 running time, "Let's Loot the Supermarket" appears to have been recorded by people who lack the ambition to put on their shoes, let alone liberate needed supplies, and short tracks like "Sparrows and Wires" and "Sidney B. Goode" play like comic sketches without punch lines. Disposable is fascinating as a document of the U.K.'s anarchist hippie scene and where it went both right and wrong, but as entertainment, you're a lot better off listening to Ptooff!. Or looting a supermarket.
Product Details
- Release Date:
- 05/26/2009
- Label:
- Esoteric
- 5013929721920
- catalogNumber:
- 2119
- Rank:
- 119994
Album Credits
Performance CreditsDeviants Primary Artist
Mick Farren Vocals,12-string Guitar
Sid Bishop Guitar,Electric Guitar,Sitar,12-string Guitar
Karl Dallas Background Vocals
Tony Ferguson Organ
Dick Heckstall-Smith Saxophone,Tenor Saxophone
Dennis Hughes Organ,Piano
Russell Hunter Drums,Vocals,Hi Hat
Cord Rees Bass,Guitar,Vocals
Paul Rudolph Guitar
Duncan Sanderson Vocals
Stephen Sparkes Vocals,Narrator
Pete Brown Brooklyn Blues Blowers Trumpet
Jenny Ashworth Background Vocals
David Goodman Vocals
Technical CreditsMick Farren Original Album Producer
George Contributor
Jimmy Ashworth Contributor
Pete Brown Contributor
Andy Johns Contributor
M.J. McDonnell Contributor
Stephen Sparkes Original Album Producer
Mark Powell Liner Notes
James Mandelkau Composer
Tony "The Roadie" Wiggens Contributor
Félix Dennis Original Liner Notes
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Chapter Count
One Shots
Seventeen, that's what Kim Jaera's age is. A lone underage girl that overworks herself to de
A CEO of a prestigious company was living the life. He had it all as some people would say. He is rich
A Romantic Comedy starring You and LuHan!~
Three years after Lu Han left, Jaera
This story is currently being edited in case some of you have not yet realised. I ask you all to wait for me to finish fixing the chapters. Once I have edited a chapter I will be re-uploading it. The plot is not changing and there will be no major changes made - I am simply improving the quaity and writing to make it better to read. I h
"Be my mate. Now."
Everything was fine in Soojung's life; her life was just like a beautiful painting, painted by the most famous painter until she found out that she has to get married with a heartless gangster, a gangster that can kill her without feeling any guilt. Will she survive this marriage or fall into the darkness? "When you marry a gangster there is no turning back, you will forever be his slave."
Tao gets pushed onto his father for the summer. Then he meets a tall, blonde, idiot surfer who tests his boundaries and alters his perception on life.
Tao needed a job to help his older siblings back in China. His best friend Baekhyun told him about a job opening that his boyfriend told him about, but the thing is, it is a nanny job. ~~~ "I'll take it." Tao said with confidence. "But Tao…it's a nanny job…I know you need the money, but…you know…the job is typically for women --" "I don't care! I have to help Luhan and Yixing…I need this." Tao pleaded.
"Is she my child? Answer me Chaeyoung....." - Sehun. Before you begin reading, this is a sequel to Mission Impossible: Find Mate.http://www.asianfanfics.com/story/view/560708/mission-impossible-find-mate-fantasy-romance-supernatural-w
Kris, always in the center of abuse. His family, dead. His hope, lost. Until he stumbles upon a black haired beauty passed out, soaked from the rain. Poster Credits : ||Walker's Grahic|| &
One video camera. Two boys happily married. Wild bedroom activites. And a weird history of how they got together.
"Scars remind us where we've been.They don't have to dictate where we're going.
Behold, the peculiar story of a wealthy boy who is completely obsessed with the unknown, the core, the pure definition of living. His spoiled behavior takes place for something that is even worse. Throughout the years, Tao learns what he truly is good at.
Say you love me. Come home at night. Eat breakfast with me. Don't ignore me. Don't look at me with those cold eyes. Only if I can say it all. (2015-12-07) DONE EDITING!!
"You can't stay with me. You belong up there where you can shine bright like the star that you are… and I must stay right here where I can look up at you." Nothing interesting ever happens in the boring, sleepy town of Chugbog. When
Kris sighed. He was wondering if he should sign up for this depression blog site or not. He could use a proper way to express his depression, but... Telling complete strangers would be hard to do... He sighed once more before clicking the sign up button. They asked for a username, he put icanfly. They asked for his name, he put Wu YiFan. They asked for a nickname, he put Kris. They asked for a picture of himself,
Agit Night, a five star upscale brothel, could be described as prominence in one single location. Pomp and circumstance, with unbounding amounts of pleasure. For the customer, Agit Night was a dream. In the midst of the business aiming for higher promotions, certain employees were to be assigned for the advertisments. This will take you on an individual journey of their lives, their hardships, and them as people.
Just some random text messages between the EXO-M members.
Kris discovers that love sometimes isn't simple. But that doesn't mean it's not worth it.
You a.k.a Rei, a member of a behemoth rookie girl group, that has made a very good job breaking the world wide market under YG entertainment, named ROYAL and EXO's kungfu panda Tao were stared into a reality show named We got Married and ventured the world of a married couple for a year and half.
Hello. My name is Huang ZiTao. I'm in high school. I have depression. I selfharm. And these are my blogs about my life.


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Click on a thumbnail to go to Google Books.
Diamonds are Forever (James Bond) (original 1956; edition 2012)
by Ian Fleming
Work details
Diamonds are Forever by Ian Fleming (1956)
No current Talk conversations about this book.
Diamonds are Forever by Ian Fleming is the fourth novel featuring British Secret Service agent James Bond, 007. The book was first published in 1956.
James Bond is assigned an undercover investigation of a diamond smuggling operation from Sierra Leone to the United States. The operation is headed by the Spang brothers, two mobsters.
Aided by Tiffany Case, Bond's contact to the smuggling ring, and Felix Leiter, Bond's CIA contact, the agent discover the many corrupt activities of the mobsters
Diamonds are Forever by Ian Fleming was not as memorable as the novels before it. I enjoyed the storyline and that the character of James Bond grows, but the rest seemed to be a bit slow and less interesting.
Mr. Fleming could not write Las Vegas, the city seems to be lackluster in his writing and the Vegas mob is no match for Bond. M, Bond's boss, seems to think that the mobsters are worse than the Russians, I half expected him to either be joking (unlikely) or get fired for being unable to read the enemy (he didn't).
The one thing that does go for this book is that Mr. Fleming actually develops the female lead, really, the effort shows. Tiffany Case is a well-rounded character, with a personality and a wonderful sense of humor. One can see why Bond is smitten by her and enjoys her company.
The first half of the book is not very exciting, and second half of the book gets much better, but not enough the save the whole. A mediocre book which was, appropriately, made into a very mediocre movie, the two have very little in common, but it is a sweet coincidence.
For more reviews and bookish posts please visit: http://www.ManOfLaBook.com
One of two Bond books I read on the beach in Cancun over the holidays this year. Always a great time. The movies are fun of course, but the novels are more enjoyable for me. The usual Fleming issues are here—sometimes sub-par dialogue, period racism, ridiculous American characters—but he was a tremendous describer of things and places and people. Not as great as others, but still much fun.
Diamonds, a fixed horse race,Las Vegas, the mob, a steam locomotive, and of course, Bond.
Diamonds, a fixed horse race,Las Vegas, the mob, a steam locomotive, and of course, Bond.
Diamonds, a fixed horse race,Las Vegas, the mob, a steam locomotive, and of course, Bond.
Is contained in
Casino Royale / Live and Let Die / Diamonds Are Forever / From Russia with Love / Dr. No / Goldfinger by Ian Fleming
The Ian Fleming classic Bond collection: part one by Ian Fleming
Casino Royale / Live and Let Die / Diamonds Are Forever / From Russia with Love / Goldfinger by Ian Fleming
Casino Royale / Live and Let Die / Moonraker / Diamonds Are Forever / From Russia with Love / Dr. No / Goldfinger / For Your Eyes Only / Thunderball / The Spy Who Loved Me / On Her Majesty's Secret Service / You Only Live Twice / The Man with the Golden Gun / Octopussy and 007 in New York by Ian Fleming
Has the adaptation
References to this work on external resources.
Wikipedia in English (2)
Amazon.com Product Description (ISBN 0142002054, Paperback)
"Listen, Bond," said Tiffany Case. "It'd take more than Crabmeat Ravigotte to get me into bed with a man. In any event, since it's your check, I'm going to have caviar, and what the English call "cutlets", and some pink champagne. I don't often date a good-looking Englishman and the dinner's going to live up to the occasion."
Meet Tiffany Case, a cold, gorgeous, devil-may-care blonde; the kind of girl you could get into a lot of trouble with—if you wanted. She stands between James Bond and the leaders of a diamond-smuggling ring that stretches from Africa via London to the States. Bond uses her to infiltrate this gang, but once in America the hunter becomes the hunted. Bond is in real danger until help comes from an unlikely quarter, the ice-maiden herself …
(retrieved from Amazon Thu, 12 Mar 2015 18:21:18 -0400)
British secret agent James Bond assumes the identity of a captured courier and solicits the help of gorgeous Tiffany Case, the diamond smugglers' American go-between.
(summary from another edition)
Amazon Kindle (11 editions)
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E3 BUZZ: Women triumph, Kinect vanishes at E3
Seen and heard as the annual Electronic Entertainment Expo gears up for its three-day run at the Los Angeles Convention Center:
Seen and heard as the annual Electronic Entertainment Expo gears up for its three-day run at the Los Angeles Convention Center:
Microsoft played to the hearts of gamers on Monday with word that they will be able to switch on beloved old video games on new-generation Xbox One consoles.
8:30 p.m. PDT
Kunal Bahl's American dream was coming together in late 2007. He had Ivy League degrees in business and engineering, a debut job at Microsoft and a roadmap to the career he'd always wanted in Silicon Valley.
Microsoft on Wednesday set out to boost workplace collaboration with a giant Surface Hub touch screen tailored for brainstorming.
Microsoft on Tuesday unveiled an Xbox One console with double the memory space that will hit the market as the Electronic Entertainment Expo (E3) video game extravaganza gets under way next week.
Did the cross-country drive that you planned using an online mapping service take twice as long as expected?
Looking for a new app for making "to-do" lists on your Apple or Android phone? You could use Apple's Reminders or Google's Keep. But Microsoft is hoping you'll try Wunderlist, created by a German tech startup that Microsoft ...
Not too long ago, Microsoft mailed loyal Xbox customers an e-card encoded with twenty-five cents' worth of Microsoft points. The software behemoth might have thought it was showing appreciation. But recipients of the company's ...
Microsoft has agreed to acquire 6Wunderkinder GmbH, a Berlin-based startup behind the Wunderlist to-do list app, for between $100-200 million (91-182 million euros), the Wall Street Journal reported on Tuesday.


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Showing 61 - 80 of 753
Schmidt a finalist for National Book Award
Okay for Now, the latest young adult novel by Gary Schmidt, could win top honors from the National Book Association.
November 03, 2011 | Myrna Anderson
Yonker is Professor of the Year
This year, Julie Yonker received the senior class' highest honor—and the traditional donuts.
April 30, 2013 | Myrna Anderson
Biographies from another era
Part of the homework in psychology 209 is creating the life histories of older adults.
May 09, 2012 | Myrna Anderson
The psychology of forgiveness
Psychology professor Blake Riek studies the motivators behind asking for forgiveness.
March 14, 2012 | Myrna Anderson
Stehouwer wins Professor of the Year
Scott Stehouwer, a 34-year veteran of the psychology department, is the students' choice.
April 30, 2012 | Myrna Anderson
More prodigal
Betty Sanderson discovered 18th-century prints on a Prodigal Son theme in Calvin's permanent collection.
March 21, 2012 | Myrna Anderson
Prayer Summit reflections
Calvin staff and faculty share their experiences of the CRC Prayer Summit held in April at All Nations Church.
May 08, 2012 | Myrna Anderson
Nursing students offer care at Supper House
A northwest emergency food center is one place Calvin nurses are learning about healthcare.
March 27, 2013 | Myrna Anderson
Tigchelaar: Professor of the Year
Biology professor Peter Tigchelaar wins Professor of the Year.
May 10, 2010 | Myrna Anderson
An online education report card
Students and faculty appraise the online classes offered through Calvin's 2012 pilot program.
June 28, 2012 | Myrna Anderson
A $25,000 grant helps stroke survivors reclaim their voice in the church
Peggy Goetz is studying how people with communications disorders re-integrate into their churches.
May 06, 2013 | Myrna Anderson
Q&A: Randy Wolthuis
After 10 years as director of the Broene Counseling Center, Randy Wolthuis is leaving Calvin to re-enter private practice as a specialist in marital issues.
May 10, 2010 | Myrna Anderson
Senior Design Open House
Senior engineers are doing a lot of fine-tuning (and snacking) as they get ready for their annual design showcase.
May 04, 2012 | Myrna Anderson
Calvin hosts Laughfest
Upright Citizens Brigade is coming to Calvin, and Calvin Improv is the opening act.
February 24, 2012 | Myrna Anderson
Calvin Gives Back
Students will have an opportunity to thank donors during Thanksgiving Week.
November 16, 2012 | Myrna Anderson
Telling Yemen's story in the West
James Robin King '04 helps scholars from turbulent countries find refuge.
October 19, 2011 | Gayle Boss
Michigan's student teacher of the year
Christine Orlando was recently chosen as the Michigan Student Teacher/Intern of the Year.
May 26, 2011 | Myrna Anderson
Managing the mowers
They had 28 applicants, and Paul Campbell and Tyler Smies knew what they were looking for: kids who could make eye contact; kids who could make conversation; kids who could show up on time.
July 09, 2010 | Myrna Anderson
Senior wins regional BizPlan
Calvin senior business major Kelly LeCoy bested the field at the 2011 Regional BizPlan.
April 13, 2011 | Myrna Anderson
Spring Break Service Trips Set to Depart
From March 17 through 25, while students nationwide join the annual spring break exodus to the beach, 75 Calvin students with less leisurely agendas will be trekking to seven locales on the college's spring break service-learning trips.
March 10, 2006 | Myrna Anderson


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iHerb Customer Reviews
Savings of: $0.50 (13% off)
Sorry, this product is no longer in stock.
Note: Korean Customs will quarantine and inspect this item before final shipment to the customer. Please be advised that ordering this item could cause delivery delays
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Was never a coconut fan. But since discovering this product....luv it...put it in a lot of things. Everything from veggies to raw desserts. Yum!! And it's nutritious. Definitely recommend.
Organic Coconut
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finely shredded
Posted by Reviewer1965588 on Dec 05, 2011
this is very finely shredded coconut, it's good but I prefer a less fine grade of coconut next time. thanks
Tasty, good for baking
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Best taste and freshness I've encountered
just coconut
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organic coconut...nothing more, nothing less. Finely shredded and a bit on the dry side. If you prefer a flaked, more moist coconut, this isn't it.
Good stuff
Posted by Reviewer2998344 on Jul 03, 2012
This is good. Tastes nice.
Posted by Reviewer2120882 on Oct 10, 2011
This is my favorite coconut. It's very fine the way I like it. I mostly use it in plain yogurt with added chopped walnuts, some frozen fruit and a little stevia.
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David Bradshaw
Research Manager, European Public Cloud Services, IDC EMEA
David Bradshaw is research manager for software and services in Europe, and his focus of research is on the relationship between software (especially but not exclusively business applications) and IT services. His research streams include software/service ecosystems, software as a service and software delivery models.
Western Europe Public Cloud Services Market Shares, 2014
David Bradshaw, Marianne Kolding, Jesper Markmann
Dec 2015 - Doc # EMEA40735715 Market Share
This IDC study focuses on the 10 largest public cloud services vendors in Western Europe and shows how they performed against market trends. It provides a view of the top 10 vendors' market shares and growth for 2014.: "Among the th ...purchase document
Oracle in Front of the Platform-as-a-Service Mountain: An EMEA Point of View
David Bradshaw, Philip Carnelley, Giorgio Nebuloni
Nov 2015 - Doc # EMEA40614515 Flash
This IDC Flash summarizes some of the key learnings from Oracle OpenWorld 2015, with a specific focus on Oracle's platform-as-a-service (PaaS) strategy and its significance in the EMEA marketplace. purchase document


text:
Hayti News
Local news for Hayti, SD continually updated from thousands of sources on the web.
Minor Injuries In 2 Separate Semi Accidents In Hamlin County
Sep 17, 2015 | KDLT-TV Sioux Falls | Comment?
Two semi rollover accidents in two days in Hamlin Co.
Sep 17, 2015 | KSFY | Comment?
Hayti news is powered by NewsRank™
Updated: Thu Sep 17, 2015 10:07 am
Copyright © 2016 Topix LLC


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LG Lucid 2 benchmarks
- Performance BenchmarksIf there's one thing smartphone consumers value extremely highly, that's lightning-fast system performance. But how do you tell if a device has the necessary power to carry you through the seas of demanding apps and beyond? The answer is simple - through synthetic benchmarking! Thankfully, there are now tools that are professional enough to give us a good idea about the punch our devices really pack.
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The first two authors contributed equally to this work.
Obesity Attenuates the Contribution of African Admixture to the Insulin Secretory Profile in Peripubertal Children: A Longitudinal Analysis
Version of Record online: 6 SEP 2012
DOI: 10.1038/oby.2008.648
2009 North American Association for the Study of Obesity (NAASO)
Volume 17, Issue 7, pages 1318–1325, July 2009
Additional Information
How to Cite
Casazza, K., Phadke, R. P., Fernandez, J. R., Watanabe, R. M., Goran, M. I. and Gower, B. A. (2009), Obesity Attenuates the Contribution of African Admixture to the Insulin Secretory Profile in Peripubertal Children: A Longitudinal Analysis. Obesity, 17: 1318–1325. doi: 10.1038/oby.2008.648
Publication History
- Issue online: 6 SEP 2012
- Version of Record online: 6 SEP 2012
- Received 25 August 2008; accepted 18 December 2008
- Abstract
- Article
- References
- Cited By
The pubertal transition has been identified as a time of risk for development of type 2 diabetes, particularly among vulnerable groups, such as African Americans (AAs). Documented ethnic differences in insulin secretory dynamics may predispose overweight AA adolescents to risk for type 2 diabetes. The objectives of this longitudinal study were to quantify insulin secretion and clearance in a cohort of 90 AA and European American (EA) children over the pubertal transition and to explore the association of genetic factors and adiposity with repeated measures of insulin secretion and clearance during this critical period. Insulin sensitivity was determined by intravenous glucose tolerance test (IVGTT) and minimal modeling; insulin secretion and clearance by C-peptide modeling; genetic ancestry by admixture analysis. Mixed-model longitudinal analysis indicated that African genetic admixture (AfADM) was independently and positively associated with first-phase insulin secretion within the entire group (P < 0.001), and among lean children (P < 0.01). When examined within pubertal stage, this relationship became significant at Tanner stage 3. Total body fat was a significant determinant of first-phase insulin secretion overall and among obese children (P < 0.001). Total body fat, but not AfADM, was associated with insulin clearance (P < 0.001). In conclusion, genetic factors, as reflected in AfADM, may explain greater first-phase insulin secretion among peripubertal AA vs. EA; however, the influence of genetic factors is superseded by adiposity. The pubertal transition may affect the development of the β-cell response to glucose in a manner that differs with ethnic/genetic background.


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Pre-Order Your Copy of Harry Potter and the Cursed Child Parts I & II from Red Rock Books and Get an Exclusive Invitation to Our Midnight Release Party on July 30th!
May 2016 Sale
April 2016 Sale!
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January 2016 Sale!
For the month of January, all of our USED general fiction, mystery and romance hardcovers are only $3.00 each! Come search the thousands of hardcovers in our stacks and stock up on your favorites for only $3.00 each!!
BOOK SIGNING for Thomas J.J. Starr DECEMBER 19th 1:00PM-3:00PM
Join us for a book signing for Thomas Starr, the author of Virtual Vengeance. Thomas will be here signing copies of his exciting new novel "Virtual Vengeance" on Saturday December 19th from 1:00PM to 3:00PM.
Petroglyph Festival 2015
Visit our booth at the 2015 Petroglyph Festival, which takes place November 7th and 8th. Our booth will be set up at the street fair on the corner of Ridgecrest Blvd and Balsam St. Death Valley Jim will be chatting and signing books at our from 12-2 on both Saturday and Sunday.
November 2015 Sale!
Our November sale is 25% off all cook books and craft books! That includes new, used, paperback, hardcover and even some special orders.


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Free Summer Movies are Back!
Movies show Monday through Friday at 9:30 AM.
Doors open at 9:00 AM.
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Norm of the North
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August 15-19
How to Train Your Dragon 2
August 22-26
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They make great gifts!


text:
First Take
Archived Podcasts
Gordon's Reinstatement: 7/26/16
Stephen A. Smith and Max Kellerman debate Josh Gordon's four-game suspension, Tony Kornheiser's recent comments, the Aroldis Chapman deal and more.
The New Era Begins: 7/25/16
The new era of First Take begins as Max Kellerman joins the show to debate Stephen A. on Kevin Durant to the Warriors, if athletes should be activists and much more!
NBA Moves ASG: 7/22/16
Marly Rivera, Claudia Trejos and Anita Marks in for the crew debate a variety of issues such as the NBA moving the All-Star Game from Charlotte, Le'Veon Bell getting suspended by the NFL again for failing a drug test and much more!
Kobe's Letter : 7/21/16
Anita Marks, Marly Rivera and Claudia Trejos debate about the impact of the Rooney Rule, Kobe Bryant's letter, the state of boxing and more.
The Big 12 Preview: 7/20/16
Jonathon Coachman and Max Bretos debate Kevin Durant's latest comments and If Tiger Woods will ever win a tournament again. Plus, Big-12 college football coaches join the debate desk.
Hurt Feelings? : 7/19/16
Max Bretos and Jonathan Coachman debate if Russell Westbrook is right to be upset at Kevin Durant and are joined by Nick Saban and Kevin Sumlin to discuss the upcoming CFB season.
Patriots Expectations : 7/18/16
Jonathan Coachman and Max Bretos take over First Take to discuss Jimmy Garoppolo's immediate impact for the Patriots, the ripple effect of Brock Lesnar's violation and more. Plus, Georgia coach Kirby Smart is in studio.
Give The Thunder Credit : 7/15/16
Jalen and Jacoby host ESPN Radio's takeover of First Take and debate if the Thunder were the best team in the playoffs, if Von Miller will sign the deal offered to him by the Broncos, where Russell Westbrook is likely to go and more.
Brady's Newest Request: 7/14/16
Freddie Coleman and Bomani Jones discuss Tom Brady's Deflategate fight, athletes taking a stance on social issues, where Russell Westbrook is most likely to end up and more.
Appeal Rejected: 7/13/16
Rick Dipietro, Don La Greca and Peter Rosenberg debate Tom Brady's appeal being rejected, the Fitzpatrick-Jets situation and if the MLB All-Star Game should change it's format.
Tim Duncan Legacy: 7/12/16
Tom Waddle and Mark Silverman debate if Tim Duncan is a top 10 player of all time, if the Lakers should trade for Russell Westbrook, who was the best player drafted in the 90's and much more.
NBA Free Agency Analysis: 7/11/16
John Ireland and Steve Mason in for Stephen A. Smith debate if Kevin Durant made a good move by joining the Warriors and if Dwyane Wade can thrive with the Bulls. Plus, First Take unveils it's newest debater!
Midnight Marauders: 7/1/16
Freddie Coleman, Anita Marks and Ohm Youngmisuk cover Johnny Manziel's future, LeBron James' value, the start of free agency in the NBA and more.
Trying Your Luck?: 6/30/16
Kate Fagan, Jane McManus and Sarah Spain debate about Andrew Luck's new contract, Kevin Durant's future, the Knicks' pursuit of Joakim Noah, the state of U.S. soccer and more.
Will LeBron & Wade Ever Team Up Again?: 6/29/16
Kate Fagan, Jane McManus and Sarah Spain debate if LeBron James and Dwyane Wade will ever team up again and the importance of Johnny Manziel's instagram. Plus, they delve into Pat Summitt's legacy after her passing yesterday.
Remembering Pat Summitt & Buddy Ryan: 6/28/16
Jorge Sedano, Ohm Youngmisuk and Freddie Coleman remember Pat Summitt and Buddy Ryan on the day that the two all time great coaches passed away.
NBA Draft Recap: 6/24/16
Will Cain, Jorge Sedano and Anita Marks debate if Ben Simmons is a franchise player, if one-and-done players are a good thing and discuss their biggest takeaways from the 2016 NBA draft.
Coach Cal: 6/23/16
Stephen A. Smith and Will Cain debate where Kevin Durant will end up in free agency if he does not stick with the Thunder and Derrick Rose's trade to the Knicks. Plus, Kentucky coach John Calipari discusses a variety of NBA and NCAA topics.
Durant Landing Spot?: 6/22/16
Jorge Sedano, Kate Fagan and Will Cain discuss where Kevin Durant will end up if not with the Thunder and who will history look at more favorably Patriots or Warriors. Plus, they react to Charles Barkley's comments on LeBron James.
Skip's Final show: 6/21/16
Skip Bayless and Stephen A. Smith debate, If Lebron will be better then Jordan, who was right about Tim Tebow and if Skip would still pick RG3 over Luck.
Winners And Losers: 6/20/16
Stephen A. Smith and Skip Bayless debate if the Cavs won or Warriors lost the title, if LeBron deserved the MVP and the legacies of Stephen Curry and LeBron James.
Reax To Game 6: 6/17/16
Skip Bayless and Stephen A. Smith share their takes on the Cavaliers' victory over the Warriors in Game 6 of the NBA Finals, Stephen Curry's ejection and Ayesha Curry's tweets.
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Skip Bayless and Stephen A. Smith debate who wins Game 6 of the NBA Finals and If Draymond Green or Stephen Curry is more important to the Warriors. Plus, reaction to part 3 of the 30 for 30 series "O.J.: Made in America".
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Skip Bayless and Stephen A Smith debate what is needed to win Game 6 of the NBA Finals, if Tom Brady can win against the NFL and are joined by NBA prospect Brandon Ingram and Patriots TE Martellus Bennett.
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Skip Bayless and Stephen A. Smith debate how much of a difference does Draymond Green make for the Warriors, if Kyrie Irving or LeBron James was more important in Game 5 and grade Stephen Curry's finals performance.
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Skip Bayless and Stephen A. Smith debate about the NBA's suspension of Draymond Green for Game 5 and the pressure that LeBron James is under. Plus, more on the first part of O.J.: Made in America.
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Skip Bayless and Stephen A. Smith debate who will win Game 4 The Finals and if we will ever see another Muhammad Ali. Plus, Joseph Sikora joins the debate desk.
Grading LeBron's Performance: 6/9/16
Skip Bayless and Stephen A. Smith debate the Cavs getting back into the NBA Finals after beating the Warriors in Game 3. What grade do they give LeBron? Can they keep it up?
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Skip Bayless and Stephen A. Smith debate how important Game 3 is for Lebron James' legacy with the Cavaliers and Heat. Plus, Phil Jackson's comments comparing him to Michael Jordan and if the 2001 Lakers would be the 2016 Warriors.
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Twin studies comparing identical and fraternal twins consistently show substantial genetic influence on individual differences in learning abilities such as reading and mathematics, as well as in other cognitive abilities such as spatial ability and memory. Multivariate genetic research has shown that the same set of genes is largely responsible for genetic influence on these diverse cognitive areas. We call these "generalist genes." What differentiates these abilities is largely the environment, especially nonshared environments that make children growing up in the same family different from one another. These multivariate genetic findings of generalist genes and specialist environments have far-reaching implications for diagnosis and treatment of learning disabilities and for understanding the brain mechanisms that mediate these effects.
Why do children differ in their ability to read, to use language, or to understand mathematics? One way to answer this question is to use genetic research methods to investigate genetic and environmental causes of such differences among children. Two decades of research make it clear that genetics is a surprisingly large part of the answer for both learning abilities and learning disabilities.
A review of twin studies of language disability reported concordance (the likelihood that one twin will be affected if the other twin is affected) of 75% for monozygotic (MZ, identical) twins and 43% for dizygotic (DZ, fraternal) twins (Stromswold, 2001). For reading disability, the concordances for MZ and DZ twins are 84% and 48%, respectively. For mathematics disability, the concordances are about 70% for MZ twins and 50% for DZ twins (Oliver et al., 2004). Such studies consistently indicate substantial heritability for learning abilities as well as for disabilities.
Genetic research has moved beyond merely demonstrating the importance of genetic influence to ask more interesting questions. Multivariate genetic analysis makes it possible to ask questions about the genetic and environmental links between and within learning abilities and disabilities. The analysis focuses on the covariance (correlation) between two traits (bivariate) or multiple traits (multivariate) and uses the twin method to estimate genetic and environmental contributions to their covariance as well as the variance of each trait. In other words, multivariate genetic analysis estimates the extent to which genetic and environmental factors that affect one trait also affect another trait. Although space does not permit a detailed explanation, Figure 1 illustrates the model used in multivariate genetic analyses. Such analyses yield the genetic correlation, a statistic central to this article. The genetic correlation (which may range from 0, no correlation, to 1.0) indexes the extent to which genetic effects on one trait correlate with genetic effects on another trait independently of the heritability of the two traits. As shown in Figure 1, multivariate genetic analyses also yield analogous shared and nonshared environmental parameters. Multivariate genetic research has produced surprising findings with far-reaching implications. The purpose of this article is to review the results and to consider those implications.
Multivariate genetic research on learning abilities and disabilities consistently yields high genetic correlations. In a recent review, genetic correlations varied from .67 to 1.0 for reading versus language (five studies), .47 to .98 for reading versus mathematics (three studies) and .59 to .98 for language versus mathematics (two studies; Plomin & Kovas, 2005).
These studies examined the entire distribution of individual differences in learning abilities. What about disabilities? Few multivariate genetic studies of disabilities have been reported because they require large samples of twins for both types of disabilities in order to investigate their co-occurrence. In general, genetic research comparing abilities and disabilities suggests that what we call learning disability is merely the low end of the normal distribution of learning ability and caused by the same genetic and environmental factors responsible for learning ability (Plomin & Kovas, 2005). The implication is that when large multivariate genetic studies of disabilities are conducted, they will yield similarly high genetic correlations.
These high genetic correlations indicate that the genes affecting one ability (e.g., reading) are to a surprising extent the same genes that affect other abilities (e.g., mathematics). In order to highlight this general effect of genes, we refer to them as generalist genes. When DNA research identifies genes responsible for genetic influence on reading ability and disability, for example, we predict that most of these genes will also be associated with mathematics ability and disability because the genetic correlation between reading and mathematics is .70.
If genetic correlations are so high between learning abilities, it makes sense to expect that components within each learning domain are also highly correlated genetically, and that is the case. Genetic correlations range between .60 and .90 within each of the domains of language, reading, and mathematics (Plomin & Kovas, 2005). The most recent study used Web-based testing to assess five components of mathematics, including computation, interpretation, and non-numerical processes, in a study of more than 1,000 10-year-old twin pairs (Kovas, Petrill, & Plomin, 2007). The average genetic correlation between the five components of mathematics was .91.
It is important to emphasise that conclusions regarding generalist genes apply to common abilities and disabilities whose origins involve multiple genes and multiple environmental influences, not to rare single-gene disorders such as Phenylketonuria or chromosomal disorders such as Down syndrome. Furthermore, the generalist-genes hypothesis does not extend to rare or family-specific mutations, such as the FOXP mutation in the KE family, a family with an unusual type of speech-language impairment that includes deficits in oro-facial motor control. (Lai, Fisher, Hurst, Vargha-Khadem, & Monaco, 2001). The FOXP mutation appears to be both necessary and sufficient to cause this impairment in the 15 affected KE family members but does not contribute to genetic variation in common language disabilities (Meaburn, Dale, Craig, & Plomin, 2002).
Instead of thinking about rare genetic disorders caused by a single-gene mutation of the sort that Mendel investigated in the pea plant, it is now generally accepted that common disorders are caused by many genes, which implies that each of these genes will have only a small effect. These multiple genetic variants of small effect are called quantitative trait loci (QTLs), referring to the loci in the DNA that contribute to the variation in continuously (quantitatively) distributed traits. If, as is now generally accepted, disorders represent the quantitative extremes of the normal variation in complex traits, QTLs contribute to disorders interchangeably and additively as probabilistic risk factors.
Much multivariate genetic research has focused on cognitive abilities, such as verbal, spatial, and memory abilities, rather than on learning abilities. This research consistently finds genetic correlations greater than .50 and often near 1.0 across diverse cognitive abilities (Deary, Spinath, & Bates, 2006). Similar results suggesting substantial genetic overlap have been found for more basic information-processing measures, such as speed of processing, as well as measures of brain volume (Deary et al., 2006).
Phenotypic (observed) correlations among diverse tests of cognitive abilities led Charles Spearman in 1904 to call this general factor g in order to avoid the many connotations of the word intelligence. To what extent do generalist genes for g overlap with generalist genes for learning abilities? A review of about a dozen such studies concludes that genetic correlations between g and learning abilities are substantial but somewhat lower than the genetic correlations among learning abilities (Plomin & Kovas, 2005). This result suggests that most (but not all) generalist genes that affect learning abilities are even more general in that they also affect other sorts of cognitive abilities included in the g factor.
As we have shown, genetic correlations among learning abilities and disabilities are substantial—about .70 on average—which suggests that what they have in common is largely genetic in origin. However, genetic correlations are less than 1.0, which means that genes also contribute to making children better at some abilities than others. In other words, some relatively specialist genes (influencing some abilities but not others) also exist. As mentioned earlier, when DNA research identifies QTLs responsible for genetic influence on reading ability, we predict that most of the QTLs will also be associated with mathematics ability. However, we also predict that some of these QTLs will not be associated with mathematics. Because genetic influence on learning abilities is substantial, such specialist genes contribute importantly to dissociations among learning abilities and disabilities even though most genes are generalists.
Multivariate genetic research also has an interesting story to tell about environmental influences on learning abilities and disabilities. Genetic research distinguishes two types of environmental influences. Those that make family members similar are called shared environment. The rest, those that do not contribute to resemblance among family members, are called nonshared environment, and this category also includes error of measurement. Multivariate genetic analyses indicate that shared environmental influences are generalists: Shared environmental correlations among learning and cognitive abilities are as high as genetic correlations. For example, in the two recent studies, the shared-environmental correlation was .74 between reading and mathematics at 7 years (Kovas, Harlaar, Petrill, & Plomin, 2005), and the average shared-environmental correlation was .86 between five components of mathematics at 10 years (Kovas et al., 2007). An obvious hypothesis that has not yet been rigorously tested is that some monolithic factors such as the family's socioeconomic status or school quality might be responsible for these generalist shared-environmental effects.
In contrast to these generalist effects of shared environment, nonshared environmental effects are specialists: Nonshared environmental correlations are low. For example, in the same two studies, the nonshared environmental correlation was .39 between reading and mathematics at 7 years (Kovas et al., 2005), and the average nonshared environmental correlation was .24 between five components of mathematics at 10 years (Kovas et al., 2007).
Nearly all research attempting to identify specific sources of nonshared environment has focused on family environments rather than school environments and on personality and behavior problems rather than learning abilities. Nonetheless, such research should be informative for future research that will attempt to identify nonshared environments that affect learning abilities. A meta-analysis of 43 papers relating differential family experience of siblings to differential outcomes concluded that "measured nonshared environmental variables do not account for a substantial portion of nonshared variability" (Turkheimer & Waldron, 2000, p. 78).
The search for nonshared environments might best begin outside the family. For example, initial research supports the hypothesis that peer influence may be an important candidate for a nonshared environment as siblings make their own individual ways in the world outside their family (Iervolino et al., 2002). However, peers would not seem to be a likely explanation for why nonshared environmental factors change so much from year to year, nor why nonshared environmental factors differ from one academic subject to another (Kovas, Haworth, Dale, & Plomin, in press). Perceptions of the environment may be an important direction for research because they are specific to the child. A recent study of 3,000 pairs of 9-year-old twin pairs found that children's perceptions of school experiences were significantly but modestly influenced by genetic factors (20% of the variance), but that most of the variance (65%) was due to nonshared environment (Walker & Plomin, 2006). However, the problem is that these nonshared environmental experiences hardly relate to nonshared environmental variance in academic achievement.
We also need to consider the possibility that chance contributes to nonshared environment in terms of random noise, idiosyncratic experiences, or the subtle interplay of a concatenation of events. However, chance might only be a label for our current ignorance about the environmental processes by which children—even pairs of MZ twins—in the same family and same classroom come to be so different.
Even though we have a long way to go to understand the nonshared environmental influences that are the source of specialist environments, there are important implications now of thinking about specialist environments in relation to education. Almost all work on school environments focuses on shared environmental factors such as family background and school and teacher quality. However, such shared environmental influences have modest effects and, at least for cognitive abilities, decline sharply in importance from childhood to adolescence (Deary et al., 2006). Moreover, shared environmental influences act as generalists. More important, and of increasing importance during development, are nonshared environmental influences. As we have described, multivariate genetic research shows that these environmental factors primarily work as specialists contributing to differences in children's performances in different areas. One implication is that educational influences might have their greatest impact on remediating discrepant performances among learning abilities (such as differences in reading and mathematics) and discrepancies between learning abilities and cognitive abilities, which is one way to view the topic of over- and under-achievement.
Definitive proof of the importance of generalist genes will come from molecular-genetic research that identifies DNA associated with learning and cognitive abilities and disabilities. The multivariate genetic research reviewed here leads to a clear prediction: Most (but not all) genes found to be associated with a particular learning ability or disability will also be associated with other learning abilities and disabilities. In addition, most (but not all) of these generalist genes for learning abilities (such as reading and mathematics) will also be associated with other cognitive abilities (such as memory and spatial ability).
A major reason why identification of genes has been slower than anticipated is that there are likely to be many more genes (QTLs) with much smaller effect sizes than had been anticipated, which means that larger studies with greater power to detect small effects are needed (Zondervan & Cardon, 2004). Optimism is warranted with the advent of completely new approaches such as whole-genome association studies involving thousands of DNA markers genotyped on microarrays (slides the size of a postage stamp that contain millions of DNA sequences to which single stranded DNA or RNA can hybridise; Carlson, Eberle, Kruglyak, & Nickerson, 2004), including microarray genotyping of DNA pooled across large samples of learning-disabled individuals and controls (Butcher, Kennedy, & Plomin, 2006). The good news from the generalist-genes theory is the prediction that the same set of genes is associated with most learning disabilities. Studies that collect data on multiple phenotypes can empirically test the generalist-genes hypothesis by testing whether genes found to be associated with one phenotype (e.g., reading) also relate to other phenotypes in the same sample.
Although no genes have as yet been reliably identified as associated with learning disabilities, several linkages to chromosomal regions have been found for learning disabilities. These QTL linkage results provide some support for the theory of generalist genes. For example, for reading disability the linkages are general. That is, the same linkages appear across measures of diverse reading processes, including orthographic coding, phonological decoding, word recognition, and rapid naming (e.g., Fisher & DeFries, 2002).
When the generalist genes are identified, they will greatly accelerate research on general mechanisms at all levels of analysis from genes to brain to behavior. We have recently discussed implications of generalist genes for cognitive and brain sciences (Kovas & Plomin, 2006). Implications of generalist genes for translational research are also far-reaching. Multivariate genetic research reviewed in this article suggests that genetic "diagnoses" of learning disabilities differ from traditional diagnoses: From a genetic perspective, learning disabilities are not distinct diagnostic entities. The same set of generalist genes affects learning abilities and disabilities. Discrepancies in children's profiles of performance are largely due to specialist environments.
The writing of this article and some of the research it describes was supported in part by grants from the U.K. Medical Research Council (G0500079), the U.K. Wellcome Trust (GR75492), and the U.S. National Institutes of Health (HD46167, HD44454, HD49861).
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Explain this! (Adapted lenses)
tjdean01 wrote:
Here's the thread that left me thinking it wouldn't work
The adapter is only about a half inch long with no glass. Lens is Minolta MD. User mainly shoots full manual on film so the fact that this combo doesn't focus or meter is not a problem for her.
As eddyshoots suggested above, I'm thinking something has to give, and I'm thinking that thing might just be infinity focus.
But still, what's weird is that this 50mm lens is WIDER than expected, similar to 35mm. Now is she talking 35 in FF terms, or APS terms? On full frame terms, I see absolutely no way it is possible except if that lens she got a hold of has been modified. If the lens is perfectly adapted her FOV would be equivalent to the 50 written on her zoom lens, or 75mm in full frame terms.
So, I'm really confused here. All I can think of is that the lens has some sort of speed booster/FL reducer modified inside of it. I'll see it in a few days to solve this mystery!
It's good to see someone simply trying something rather than accepting it can't be done! I'd be a bit wary of breaking something in my camera, but if there's an adapter between the body and lens I'd expect the risk to be zilch. Hard to see what's happening in this shot.
FL - I'd take a shot, then match it with a kit zoom on the same camera then read that value to see what the effective FL is. Note that there will be a change in effective aperture if the lens to sensor distance isn't equal to the design spec of the lens, though I doubt the change will be anything significant in this case. A fast prime will still be a fast prime, just not quite as fast the number on the lens indicates.
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Summer is an exciting time at ArtWorks Academy. We have camps and classes available for students from 18 months-18 years old. The
short term commitment provides an opportunity to see your child's passions grow and their talents develop, before enrolling them for the school year.
At ArtWorks Academy, we believe performing provides opportunities for growth and development. Collaborating with peers teaches
students the importance of teamwork, while building self-confidence. Find out more about our THREE performances companies!
"My daughter has gained so much from her classes at ArtWorks. She has strengthened her dance
skills, gained confidence in her performance abilities and increased her self-esteem and self-confidence. The staff is nurturing and supportive, while teaching students skills that they
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Rush Adds Another Offer, Talks Future Plans2017 Northeast Mississippi DT Anthony Rush (6-4, 295) added an offer from a Sun Belt program recently and he updated JCFootball.com on where things stand as far as visits are…
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Illini InquirerWednesday at 7:46 PM
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Scout FantasyYesterday at 7:54 AM
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7v7 Clips Of 3-Star 2018 QB Brennan ArmstrongShelby's Brennan Armstrong is the highest rated 2018 quarterback in the state of Ohio. Here are clips of Armstrong in action last week in 7on7 action.
Scout FootballTuesday at 10:19 AM
WR Jornell Manns Enjoys Third Penn State TripPenn State was one of the first schools to offer 2018 wide receiver Jornell Manns and they have remained one of his favorites. Manns visited Happy Valley once again this past…
Scout FootballMonday at 7:51 AM
Scout300 '18 OL enjoys Louisville tripTyrone Sampson, one of the top 300 prospects nationally in the Class of 2018, made an unofficial visit and attended camp at the University of Louisville on Friday night. Sampson…
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Travell Harris Nears Top Ten Announcement2017 athlete, Travell Harris has been favoring Toledo throughout his recruitment. Now, as he nears a top ten announcement, where do the Rockets sit?
Rocket Digest07/16/2016
2018 3-Star QB Brennan Armstrong Holds 6Brennan Armstrong is the highest rated quarterback in Ohio for 2018, and the three-star recruit holds six offers to date.
Scout Football07/15/2016
2018 ATH Tye Evans Looking For First OfferOne of the more impressive all around athletes in Ohio for the class of 2018 is Nordonia's Tye Evans, and he has been a starter since his freshman season.
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Andre Harris sets mark for classy recruitsAndre Harris is a quality recruit who put together a fun list of polls for the OKPreps 2016 season.
Sooners Illustrated07/14/2016
Illini Football Recruiting Lounge: July 13Illini Inquirer publisher Jeremy Werner breaks down what could be a big Illini football recruiting month, a list of possible July visitors, the impact of Mizzou's turmoil, early…
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2018 WR Jornell Manns Holds 5 OffersMANSFIELD, Ohio -- 2018 wide receiver Jornell Manns impressed Tuesday evening in 7on7 action. The three-star recruit will visit Penn State this weekend.
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Welcome Message
The seventh International Symposium on "Geotechnical Aspects of Underground Construction in Soft Ground" will be held on 16-18 May 2011, in Roma, Italy.
Technical Committee TC 28: "Underground Construction in Soft Ground" of the International Society for Soil Mechanics and Geotechnical Engineering (ISSMGE), has a major commitment towards collecting information concerning tunnel design and construction in the urban environment, with regard to both bored and braced excavations. TC28 has already organised six International Symposia in New Delhi (1994), London (1996), Tokyo (1999), Toulouse (2002), Amsterdam (2005), and Shanghai (2008).
As the host organiser, the Italian Geotechnical Association (AGI) feel honoured to be offered the chance to hold this premier event and, together with TC 28, are delighted to welcome you as our guests to Roma, Italy.
Thanks to its unique position as the centre of the Roman Empire, its significance as a religious and cultural centre, its turbulent centuries of aristocratic and papal rivalries and upheaval, Roma has a splendid and full history, resulting in some of the finest art and architecture to survive from the last two thousand years. 2011 will also be the right time to view several ongoing and exciting projects related to underground constructions, such as the works of the new Line C of Roma Underground and of Lines 1 and 6 of nearby Napoli Underground.
Finally, Roma is a colourful and vibrant living city: we hope you shall enjoy the Italian food, the culture, the ambience and the surrounding scenery.
We are looking forward to seeing you in Roma in 2011!
|Prof. Richard Kastner
Chairman TC28
|Prof. Stefano Aversa
President AGI


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The 2016 All-Western New York girls lacrosse team
Wednesday, July 20, 2016Pos. Name School Grade Fast Fact A Claire Herrmann Hamburg 12 All-American who added 86 goals to her career total. She will play at LeMoyne. A Rebecca Izzo Hamburg 12 Finished second in scoring for the Bulldogs, who won another Section VI title. A Lexi Rockey Frontier 12 Scored more than 70 goals for the Falcons, the Section VI Class…
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About the reporters
Miguel Rodriguez, a Buffalo native and University of Rochester graduate, began his career at The News in 2003 as a sports copy editor and joined the high school beat in 2014. One of the most versatile members of the team, he has covered all manner of high school, college and professional events. The former college hockey goalie has contributed to the Sabres beat, written about youth hockey and covered the IIHF World Junior Championship and the men's and women's NCAA Frozen Four.
Budd Bailey has served in a variety of roles in Buffalo sports in the past 35 years, including reporter, talk-show host, baseball announcer, public relations staffer and author. The Syracuse graduate joined the high school coverage team in 2015. He also covers running and the National Lacrosse League's Bandits for The News.
Keith McShea, named deputy sports editor in 2014, covered high school sports at The News since his hiring in 1999. The 1995 University at Buffalo graduate and Long Island native (North Babylon Bulldogs) has been #PrepTalkLive from everything from scrimmages to state championships & helps coordinate The News' All-Western New York selections.
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How many first-team All-Western New York picks has your school had? Who made the team this year, last year, or 20 years ago, or 40?
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