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text:
Dear Brothers,
Due to circumstances beyond the Board's control, we've rescheduled
this month's County Board meeting. It will be held on Wednesday,
June 29th, at 8:00 pm, in Division 7's Hall. Your understanding and
cooperation in this matter is greatly appreciated. And we apologize
for any inconvenience.
Always in our Motto,
Jack Ryan - President
Suffolk County Board
© Copyright 1998-2016 Ancient Order of Hibernians, Suffolk County New York
Last updated March 21, 2016

subset: commoncrawl


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Donald Trump took the freak show of American politics and made it the main event. But now he says he wants to be the candidate of calm.
Molly Ball
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The social network risks losing the goodwill it built up during the Arab Spring.
Robinson Meyer
Where does Turkey go from here?
Uri Friedman
If there's one thing everyone can agree on at the Republican Convention, it's how they feel about Hillary Clinton.
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Why didn't the most talented, most influential Republican politicians—men like Chris Christie, Tom Cotton, and Paul Ryan—do more to stop Donald Trump?
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A technique that claims to help people with the condition express themselves with the help of a "facilitator" was scientifically disproven in the '90s—so why hasn't it disappeared?
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Many animals regenerate the tiny hair cells that enable hearing—and there are promising signs that people can be made to do the same.
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Some focus on the largest figures, like total student debt ($1.3 trillion) and average debt ($30,000.) So why is the most dangerous student loan number less than $5,000?
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The disease has left a terrible legacy—and another outbreak is likely.
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Why lime juice and sunlight don't mix
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Photographs of controlled explosions, blasts, kabooms, and crashes.
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An ongoing chronicle from James Fallows on Donald Trump's unprecedented and unpresidential actions, saved for posterity.
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Justin Lin's rollicking action-adventure sequel is a paean to unity, teamwork, and the best qualities of humanity.
David Sims
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10 Parks near Boonville, Missouri
New Franklin, Missouri 3.46 miles N
Fayette, Missouri 12.9 miles NE
Arrow Rock, Missouri 16.5 miles NW
Glasgow, Missouri 18.95 miles NW
Boonville, MO, USA Boonville, Missouri (map) | (660) 882-5152
Sites: 42 | Latest Rate: $30.00 | 4 Reviews
|Clean Restrooms:
|Clean Showers:
May 2009 - $30.00
Folks, I would pass on this campground. Very neglected. Had to pay at gas station. People were living in filth (looked like full time) in their trailers. Pool was a swamp cess-pool that hadn't been touched in years. - pahasapa
Aug 2007 - $25.00
This place is a dump. I notified Woodall's and they have pulled their rating. - Bob & Phyllis
Jun 2007 - $22.00
The roads are washed out. So if you have a sedan you will not be happy going down that road. If you go to "RV resorts", you will find this place to be a dump. If you want to experience lots of weeds, unlevel sites, bugs, rabbits, maybe some rodents, then this is a good place. The sewer line backed up after i dumped about 50-60 gal. fortunately i was dumping my gray water. The owners have not spent a dime on maintaining this CG. I think they are just offering it "as is" and will close it if people stop going. They really don't care. It costs them nothing to run since the owner is the diesel truck stop (and the girls that work there can't answer any questions about which sites have 50amp vs 30amp, etc...) We stayed to get some rest and play at the local casino. Next time, (if there is a next time), we will stay at the truck stop and forget the CG. - basistrdr
Boonville, Missouri (map) | (816) 916-3078
Sites: 14 | Latest Rate: $25.00 | 6 Reviews
|Clean Restrooms:
|Clean Showers:
Apr 2016 - $25.00
RV Express is just a medium-sized, gravel, self-check-in lot with hook-ups, but it was very convenient because it's right off the highway. We expected that highway or other noise might be a problem, but it wasn't--the park is actually pretty quiet. Area felt very safe. Wifi worked. Hook-ups worked. The park was also convenient because it's just behind a 24-hour McDonald's, a gas station, and a Subway--also across the road from another gas station and a Taco Bell--and a 24-hour Wal-Mart is a mile up the road. The park is safe, quiet, and convenient. We'd stay there again. - Good Travelers
Jun 2015 - $25.00
It's been said before, absentee owner and a drop box for your money. Crushed large stone lot, runs a little up hill to a high concrete retaining wall behind a service station. Services are very good, good water, power and sewer. 14 sites here with 7 taken by longtime residents in fairly good shape RVs. We parked in a pull through site, hooked toad up across street in McDonald's truck lot, since sites angle away from entrance. - Teacher's Pet
Aug 2013 - $20.00
This is your basic overnight stop, although we did stay a couple nites. It's self pay with envelopes and a drop slot. There were what looked like a couple permanent rigs there but otherwise not too crowded. Even though we're a 40ft RV, we opted for a back in and found one that fit. We unhooked in the McDonald's truck parking lot across the street & also hooked up there when we left. The park is all gravel, so I walked my dog across the street at McDonalds. Convenient for breakfast too. We had good Verizon cell & air card here. Boonville was a nice surprise downtown & the casino is in town too. We came to see the Clydesdales. We never saw anyone running the place but didn't need to. Know ahead of time that the pull thrus are higher in cost. We'd stay here again for an overnight. Nothing fancy but we had full hookups w/50 amp service and sometimes that's all you need or want in a place. - Danni
New Franklin, Missouri (map) | (660) 848-2232
Sites: 30 | Latest Rate: $33.00 | 9 Reviews
|Clean Restrooms:
|Clean Showers:
Sep 2015 - $33.00
A beautiful location with lots of trees and very few sites occupied even on a Friday night. Long pull-through sites, though only 4 sites had the 50-amp we desired. - Liv2RV
May 2015 - $29.00
The first area that could use some improvement is the signage. ---it is somewhat difficult to find the camp ground and then to find where the RV sites are located in the campground. We arrived on a Monday night and pretty much had the place to ourselves. Some bicyclists showed up at about 9 p.m. and pitched their tents right next to our RV. This is probably not what should happen since there is a separate section for tent camping. The camp location is wonderful for people using the Katy Trail, --a popular hiking and biking trail. Another not so good surprise was the electric and water hookups were only at every other RV site, meaning two sites must share one hook up. Since we had our pick of which site we wanted, this was not a problem for us but could be a problem for those who don't have hoses and electric cables long enough to reach the opposite side. The bath shower house is very much in need of cleaning and fixing up. - stocky
Oct 2014 - $32.00
We were here one night and were the only RV. The park is difficult to find; our GPS could not find it. Finally found a cop who gave good directions. Also, the staff was impossible to find; never saw a live body other than a few tent campers. Called the number on the website and always got voice mail but no callback. Finally sent email and did get response but it may have been automatic. When we left, put cash in an envelope and dropped it in a slot. This campground may be fine in summer when the Katy Trail is busy and it was fine for a one nighter but we probably would not stay here again. - Delbert
Arrow Rock, Missouri (map) | (660) 837-3330
Sites: 47 | Latest Rate: $28.00 | 19 Reviews
|Clean Restrooms:
|Clean Showers:
Apr 2016 - $28.00
Price is because we got the only full hook up site there. All other sites are electric only or just basic sites. Very pretty & well kept campground. Lots of room between sites so you're not right on your neighbors. Camp hosts were very friendly & helpful. Campground is very close to historic & lovely little town of Arrow Rock. Would definitely stay here again. - bgw5350
Apr 2016 - $23.00
We stayed in site #38, it was a little short for our 32' travel trailer and tow vehicle so we had to park sideways in front of the camper. The Verizon signal is slim to none and the park WiFi was not strong in this site. Park is nice with a hiking trail, potable water at the dump station, wood and ice for sale. Park was clean including the restrooms and showers. There is a small playground for kids. - kcjaybird
Oct 2015 - $28.00
Very quiet with good access although you need to follow signs carefully. It is remote with closest services, shopping several miles away. Only 1 fully serviced site but water is close. Dump station convenient. Close to major former railway trail for biking & hiking. Great for quiet relaxing getaway! - Kasey11
Huntsdale, Missouri (map) | (573) 445-0047
Sites: 7 | Latest Rate: $28.00 | 5 Reviews
|Clean Restrooms:
|Clean Showers:
Jul 2012 - $28.00
Still being worked on. Bathrooms but no showers. On river and close to bike trail. Good for dogs. Lots of room during week, supposedly fills up on weekends. - mjtesky
Jun 2012 - $28.00
Quiet and out of the way. Good size slots. Host was not only gracious and accommodating, but beautiful. - Boondockdad
Jun 2012 - $28.00
The positives of this campground were full hookup plus sewer, fairly close to interstate, nice host, quiet, and a boat dock. However the negatives overrode the positives for us. The small park was right on the Katy Trail and had a lot of potential. Sadly, it was overgrown and unkempt, other campers were few and a little questionable, the store was only open on weekends, and it was riverside but not scenic. It was like camping in a farm field that had not been mowed. We meant to stay and ride the trail, but we left after one night. Would not stay here again. - busyteach
Bagnell, Missouri (map) |
Sites: 106 | 0 Reviews
Columbia, Missouri (map) | (573) 657-2544
Sites: 25 | Latest Rate: $23.00 | 4 Reviews
|Clean Restrooms:
|Clean Showers:
May 2012 - $23.00
This definitely was not a family friendly atmosphere. It is a place to go and party, if that is what you're looking for. There is not easy access for full size motorhomes because of narrow roads and low trees. - Harlee79
Jun 2009 - $20.00
This is a good place to drink and party, I wouldn't take kids. It's hard to park in most sites. Weekends have many tent campers very close and walking through your area, there's very little privacy. There's one very small restroom in the store with one pay shower available during store hours and a few really nasty portable potties. I won't stop there again. - David's path
Jul 2007 - $20.00
Call in advance, the campground is pretty far out in the country and small. I'm not sure too many big rigs could be accommodated. Amenities are way down on the 1-10 scale but the location and atmosphere more than compensate. A great view of the historic Missouri River, live entertainment and friendly locals added to the ambiance. It truly feels that you've stepped way back in time. The Thai food concession added to the wonder. If your thing is bicycle riding, you're situated on 30 miles of improved RR bed - fantastic riding. Coopers Landings is out of the way but unique and we would return in a heart beat. - richb
Columbia, Missouri (map) | (573) 474-2747
Sites: 97 | Latest Rate: $40.00 | 154 Reviews
|Clean Restrooms:
|Clean Showers:
Jul 2016 - $40.00
Very nice, well tended park. Big field at the back where dogs could play off-leash. - Lots Labs
Jul 2016 - $36.00
I've reviewed this park before. We stay here yearly to visit grandkids. I've never been as impressed with it as I am today. The new owners have taken it from an acceptable place that had some maintenance problems to a showplace. Pool is very good, playground is excellent, electricity during a very hot A/C kind of stay, was flawless and the newly opened
Rec room is a good addition. I'm pleasantly recommending this park to all. - exceltraveler
Jul 2016 - $46.00
Good directional signage to get here. Lots of shade trees, clean, well landscaped sites, friendly staff. Nice pool & store. - Hulda


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Rio Tinto, BHP and their peers have spent years improving their safety records. The finance industry can learn a thing or two from the way that miners have tried to clean up their act. Not least is the ambition to attain higher standards than absolutely required by the law.
Noble CEO exit signals reduced ambitions
Yusuf Alireza is leaving the embattled commodity trader after four years in charge. Though Noble has avoided an immediate liquidity crisis, investors still question its long-term viability. Flogging its U.S. energy arm will raise cash at the expense of further shrinkage.
OPEC freeze failure could hasten oil's recovery
Producers failed to agree a deal to freeze supply at a meeting in Doha. The failure was largely due to Saudi Arabia's refusal to allow Iran to be exempted from an agreement. Prices will drop initially, but if OPEC disintegrates the stalemate could hasten crude's recovery.
BP's $20 mln Dudley payout looks crass but isn't
The oil major faces an uproar over Chief Executive Bob Dudley's bumper remuneration package despite the company slashing jobs and recording losses last year. But the criticism may be unfair. Dudley has hit key targets and drawn a line under the Gulf of Mexico disaster.
BHP admits dividend pledges and mining don't mix
The world's largest miner slashed its interim dividend 74 pct and followed rival Rio in scrapping a "progressive" policy. About time. Promising payouts will only ever go up is daft in such a cyclical sector. Consistency matters less than safeguarding the balance sheet.
Gold's prospects are dull
The precious metal isn't behaving like a safe haven should. The dollar's rise is weighing on its price, Asian demand is dented, investors don't need inflation hedges, and past price gyrations have tarnished its defensive allure. Grimmer news is needed to restore gold's lustre.
Sweeter Cairn bid is Vedanta's least bad option
Anil Agarwal's Vedanta Resources is edging towards loan covenant limits. Bondholders are losing faith in the mining tycoon's ability to tap buried cash and repay $8 bln of debt. The stress may force Agarwal to sweeten a deal to merge subsidiaries and simplify the group structure.
BHP Billiton plays catch-up with $7 bln shale hit
Plunging energy prices forced the miner to write down its U.S. oil and gas assets again. The non-cash charge is large but just brings BHP's balance sheet closer to the outside world's estimation. A bigger step would be to follow the market's lead once more and slash the dividend.
Ivan Glasenberg may be mining's last man standing
The Glencore chief outlasted his peers when the commodity boom turned in 2013. The sector may be due another shakeout in 2016 if prices keep falling. But Glasenberg's big stake in Glencore and his newfound dash of humility mean his copper plating should last another year.
Cash calls leave issuers with unfinished business
Lonmin and Standard Chartered's shares have both slipped further than theory might suggest since issuing a combined $5.5 billion of new stock. That's logical at miner Lonmin, which now has a big stock overhang. For lender StanChart, it looks like a vote of diminished confidence.
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Tempurung Seaside Lodge sits atop a small hill overlooking the South China Seas with stunning sunset and pristine white sandy beach, it is a place where dreams and reality converge. It's 2 hours drive from the city. Come and enjoy the best of borneo
Welcome to Borneo BeacHouse (Backpackers) The only colonial Beach House situated in the South of Kota Kinabalu City that provide relaxing & homely atmosphere. Strategically located only 10 minutes walk from Terminal 2 Airport. Life's a Beach
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The Las Vegas Wildcats girls basketball team won Thursday's away conference game against Sunrise Mountain by a score of 63-19.
(January 26, 2012: Las Vegas, NV 89142) The Las Vegas Wildcats basketball team scored 63 points and held the host Sunrise Mountain to 19 in the Wildcats league triumph on Thursday.
The Wildcats now sport a 11-6 record. They put it on the line next when they travel to Agassi Prep for a non-league contest on Thursday, January 26. Las Vegas will confront a team coming off a 61-28 league loss to Lincoln County (Panaca, NV). The record now stands at 1-12.
The (2-10) will now prepare for their contest against Chaparral (Las Vegas, NV). The Cowboys enter the Sunrise - Northeast contest with a 4-16 record. In their last contest, Chaparral was routed by Valley (Las Vegas, NV), 50-31, in a league contest.


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Reading FC today announced Joey van den Berg as the club's second summer arrival, after he penned a two-year deal to join the Royals. Like... ...http://www.thesportscampus.com/2016062852794/transfer-news/reading-make-second-dutch-signing-of-the-summer
Socceroos defender Trent Sainsbury has claimed September's clash with Iraq in Perth looms as one of Australia's most crucial fixtures on the road... ...https://in.news.yahoo.com/socceroos-must-start-well-road-001746843.html
Reading Football Club confirmed today the appointment of Jaap Stam as first team Manager at Madejski Stadium. The Kampen-born former PSV Eindhoven,... ...http://www.thesportscampus.com/2016061352413/english-premiership/jaap-stam-appointed-manager-of-reading-fc
PSV Eindhoven has successfully defended the Eredivisie title and won it for the second consecutive time after defeating PEC Zwolle 3-1, while... ...http://www.business-standard.com/article/news-ians/psv-eindhoven-win-second-straight-dutch-eredivisie-title-116050900298_1.html
In England, the celebrations went on at Leicester City as they marked their fairytale Premier League success with another win while champions... ...http://www.rediff.com/sports/report/footballers-of-the-weekend-jamie-vardy-shines-in-europe/20160509.htm


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It's time for everybody's favorite Hawaiian pop starlet. Anuhea, sings along with ukulele songs about simple love evoking images of black sand beaches. Think of Israel Kamakawiwo'ole, but more comely.
Fri., July 27, 8 p.m., 2012
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February 24, 2014
Double Coin Tires and CMA now has a second North American distribution center with the opening of a West Coast distribution center in Rancho Cucamonga, Calif.
The new distribution center recently completed its final phase of construction and is located at the intersection of 8th Street and Vineyard Avenue in the city of Rancho Cucamonga. The center will support the dealer and end user supply chain with shipments of the Double Coin brand and other CMA products. This is CMA's second distribution center in North America, joining the Memphis, Tenn. facility.
Built from the ground up for tire distribution optimization, the distribution center uses customized and portable racking systems that provide multiple tire storage combinations at full capacity.
The building includes a wireless mobile security monitoring system as well as dock-high and grade level bay doors with stalls for trailer parking with additional spacious areas available for expedited shipping.
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
The expert, Brian Fletcher from Eaton, will answer your questions
Kenworth Launches Essentials App for Mobile Devices
EZ Drain Valve Made For Vaporizer Drain Systems
VeeBoards Corner Protectors are Stackable
TomTom Partnership Adds Real-Time Accounting


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For our third annual list, we sought to highlight literature that exposes readers to cultures and ways of life that may be different from their own...
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The 100th day of school is approaching, and to mark the occasion, Freddy and his classmates must each collect and bring to school 100 of something. Freddy is overwhelmed by the thought, then he has a great idea to collect 100 shark trading cards. But he only has 21 cards! How will be get another 79 before the 100th day of school? Even if he had the money, his mom would NEVER let him buy that much bubble gum. Join Freddy as he plots the perfcet plan to reach his goal.
The Ready, Freddy! series has content, humor, characters and vocabulary perfect for the early chapter-book reader.
John McKinley has been drawing all his life. He is the celebrated illustrator of the Ready, Freddy! series. He and his family live in Northern California.
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The Cascadia Hotel was clean the beds were clean and the towels white, the breakfast was good and we stayed during Carnival they kept breakfast going till we came back from Jouvert at 11am. The food in the restaurant was good, like everything in Trinidad it operates on trini time things can take time to arrive. They are planning to repair the pool this summer some tiles were missing. Security in the hotel was good. I was dreading going to the this hotel after the reviews. It was a basic hotel and clean that is all I wanted.
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The Mediterranean diet is protective against cardiovascular disease; a proposed mechanism is through a reduction in systemic inflammation. It is unknown to what extent the association between the Mediterranean diet and inflammation is due to genetic or other familial factors.
We administered the Willett food frequency questionnaire to 345 middle-aged male twins and assessed adherence to the Mediterranean diet using a published adherence score. Fasting plasma levels of interleukin-6, C-reactive protein, and known cardiovascular risk factors were measured. Mixed-effect regression analyses were used to examine the relationship between diet score and inflammatory biomarkers after accounting for known cardiovascular risk factors. Adherence to the Mediterranean diet was associated with reduced levels of interleukin-6 (P<0.001) but not C-reactive protein (P=0.10) after adjustment for total energy intake, other nutritional factors, known cardiovascular risk factors, and use of supplements and medications. When the overall association of adherence to the diet with interleukin-6 levels was partitioned into between- and within-pair effects, the between-pair effect was not significant (P=0.9) and the within-pair effect was highly significant (P<0.0001). A 1-unit within-pair absolute difference in the diet score was associated with a 9% (95% CI, 4.5 to 13.6) lower interleukin-6 level.
Shared environmental and genetic factors are unlikely to play a major role in the association between adherence to the Mediterranean diet and systemic inflammation. These results support the hypothesis that reduced inflammation is an important mechanism linking Mediterranean diet to reduced cardiovascular risk.
Adherence to the Mediterranean diet appears to benefit the cardiovascular system,1,2 but the underlying mechanisms are unclear. An inverse relationship between adherence to the Mediterranean diet and biomarkers of systemic inflammation such as interleukin-6 (IL-6) and C-reactive protein (CRP)3,4 has been reported, suggesting that inflammatory processes may be implicated. However, such relations were not consistently found in randomized controlled trials.5–7 A possible reason for the inconsistent findings may be the genetic differences in the response to diet because each of the trials studied a different European population: Italian,5 Spanish,6 and German.7 In addition, because dietary habits are acquired while growing up, they are likely to be associated with other environmental conditions shared by members of the same family such as unmeasured socioeconomic and lifestyle factors, which also can influence inflammation and thus act as confounders. However, no prior study has controlled for the influence of familial factors in the association between the Mediterranean diet and inflammation.
Twins are a powerful resource for dissecting complex associations because they allow us to control for unmeasured and unknown confounding such as genetic factors and socioeconomic, behavioral, and lifestyle characteristics acquired by twins growing up in the same family. Using a sample of monozygotic (MZ) and dizygotic (DZ) middle-aged male twins raised in the same family, we examined the relationship between adherence to the Mediterranean diet and circulating biomarkers of inflammation. We sought to determine whether the association persisted after accounting for common genetic and environmental factors by comparing each twin with his co-twin.
The Twins Heart Study (THS) is an investigation of psychological, behavioral, and biological risk factors for subclinical cardiovascular disease using twins. It included 180 pairs of MZ and DZ male twins from the Vietnam Era Twin Registry8 who were born between 1946 and 1956 and were free of symptomatic cardiovascular diseases on the basis of survey data collected in 1990.9 The Vietnam Era Twin Registry includes 7369 middle-aged male-male twin pairs, both of whom served in the US military during the time of the Vietnam War. Zygosity was determined using similarity questionnaires supplemented with blood group typing data abstracted from military records.10 For the THS, random samples of twins in 2 strata were selected from the registry; 1 stratum included twins discordant for a lifetime history of major depression, and in a second stratum, neither twin had a history of depression. All twins were examined at the Emory University General Clinical Research Center between March 2002 and March 2006; their medical history was updated at the examination. We excluded twins with missing dietary data, implausible energy intake (≥6000 or <500 kcal/d),11 or circulating IL-6 levels >10 pg/mL, defined as a cutoff for low-grade systemic inflammation. The study protocol was approved by the Institutional Review Board at Emory University, and informed consent was obtained from all subjects.
We used the Willett self-administered semiquantitative food frequency questionnaire,12 which collected dietary data over the past 12 months. The questionnaire classifies average food intake according to 9 frequency categories ranging from "almost never or less than once per month" to "≥6 times/d" using standardized portion sizes for each dietary item, including beverages and nutritional supplements. Questionnaires were scored by the Nutrition Questionnaire Service Center, Channing Laboratory, Harvard University, and nutrient intake data were derived following the nutrient database of the US Department of Agriculture. Daily food intake in grams was calculated from food intake frequency and portion sizes.
The term Mediterranean diet refers to a dietary pattern typical of many regions in Greece and southern Italy in the early 1960s, including a high intake of fruits, vegetables, bread, other forms of cereals, potatoes, beans, nuts, and seeds; low to moderate amounts of dairy products, fish, poultry, and wine; low amounts of red meat; eggs consumed no more than 4 times weekly; and olive oil as an important fat source.13 We measured adherence to the Mediterranean diet using the Mediterranean Diet Score (MDS) described by Trichopoulou et al1 based on a priori assumptions about 9 desirable or undesirable dietary components (Table I in the online Data Supplement): (1) 7 desirable dietary components for health, including cereals (excluding potatoes), vegetables, fruits and nuts, legumes, fish, dietary ratio of monounsaturated to saturated fatty acids (mainly a result of the use of olive oil as the main cooking oil in the Mediterranean diet), and moderate alcohol consumption, and (2) 2 undesirable dietary components for health, including meat and dairy food products. The score was constructed using zygosity-specific, rather than gender-specific, median of food intake (adjusted to 2500 kcal)14 to conduct analyses stratified by zygosity in our all-male sample. We assigned a value of 1 to a high intake (greater than or equal to the median) of each desirable component, a value of 1 to a low intake (<median) of each undesirable food, and a value of 0 to all other intakes.14 For alcohol, a value of 1 was assigned to moderate consumption, ie, intake above the zygosity-specific median (2.38 g/d for MZ and 1.72 g/d for DZ) and ≤33 g/d. The latter, the daily upper limit of alcohol intake considered "moderate" among American men,15 equals ≈2 alcoholic drinks per day.15,16 The MDS was the sum of all values from the 9 components, ranging from 0 to 9; the higher the score was, the greater the adherence to the Mediterranean diet was.
We also devised 3 slight variations of the MDS to evaluate the robustness of our findings. First, we followed an earlier method published by Trichopoulou et al14 to calculate a score, MDS1, ranging from 0 to 8 in which fish was included in the meat group17 and potatoes and eggs were included among cereals and meats, respectively.14 A second variant, MDS2, was similar to the MDS1 except fish was excluded from meat.17 Fish intake as a covariate was forced into the models. In a third variation of the score, MDS3, we excluded fish from the meat group and included fish as a desirable component.
We assessed smoking (never smoked and current and past smoker), education, and marital status using standardized questionnaires. Physical activity was evaluated with the Atherosclerosis Risk in Communities study Baecke questionnaire.18 Waist and hip circumference were measured and used to calculate a waist-to-hip ratio. Systolic and diastolic blood pressures were measured with a mercury sphygmomanometer according to a standard protocol.19 Hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg or current use of antihypertensive medicines. Diabetes was defined as a fasting plasma glucose concentration ≥126 mg/dL20 or current treatment with insulin or oral hypoglycemic agents. Depressive symptoms were measured with the Beck Depression Inventory, which yielded a continuous score.21 Current uses of aspirin and statins also were recorded.
Plasma samples were separated from 9-hour overnight fasting blood samples and stored at −80°C until analysis. Concentrations of glucose, triglycerides, and total, low-, and high-density lipoprotein cholesterol were measured with standardized methods. Plasma IL-6 concentrations were determined with commercial enzyme-linked, high-sensitivity immunosorbent kits (R&D Systems, Minneapolis, Minn). High-sensitivity CRP (hsCRP) concentrations were tested with the high-sensitivity Beckman Coulter assay. The interassay and intra-assay variabilities for all assays were <10%; the samples were analyzed blindly; and twin pairs were assessed in the same analytical run.
We ranked twins in each pair on the basis of their MDS scores and calculated the within-pair absolute difference in the MDS as the difference between a twin with a higher MDS score and his twin brother with a lower MDS score. Inflammatory biomarkers were log-transformed because of skewed distributions. Intraclass correlation coefficients were calculated for the MDS and log-transformed inflammatory biomarkers in MZ and DZ twins. The association between the MDS and inflammatory markers was assessed by fitting linear regression models adapted for twin studies.22 We first used the entire sample by treating twins as individuals and accounting for the twin pair clustering. The MDS was analyzed primarily as a continuous variable and secondarily as a 4-level variable categorized as 0 to 3, 4, 5, and 6 to 9. Category midpoints were used for analyses.23 Because the dependent variables were log-transformed and the association was inverse, we expressed the results as percent difference of the nontransformed values by using the following formula: [1−(expβ)]×100 (%), where β is the regression coefficient and expβ returns the exponential value of the parameter. The "base model" adjusted only for total energy intake and nutritional factors that were not part of the MDS, including potato and egg consumption.1 To this model, we subsequently added sociodemographic factors, including age, years of education, and current marital status; lifestyle factors such as smoking, waist-to-hip ratio, and physical activity; comorbidity and cardiovascular risk factors, including previous coronary heart diseases, depressive symptoms (Beck Depression Inventory score), fasting glucose, systolic blood pressure, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol; supplements and medications such as fish oil supplements; and use of aspirin and statins. Potential multicollinearity was investigated using condition indexes and variance decomposition proportions by means of a SAS macro (SAS Institute, Inc, Cary, NC) using criteria including both a condition index of ≥20 and at least 2 nonintercept variables with variance decomposition proportions values of ≥0.5.24
Next, we performed within-pair analyses to examine differences in inflammatory biomarkers between co-twins in each pair. The within-pair effects are inherently controlled for demographic, shared familial, and environmental influences; in addition, environmental factors during the day of testing are controlled because co-twins were examined at the same time and under the same conditions. We fitted mixed-effects models for twins,22 which allow partitioning within- and between-pair differences in the dependent variable as a function of the independent variables. In these models, the within-pair β coefficient describes the individual twin variation from the twin pair average; this formulation has the advantage of being independent of twin ordering. The between-pair regression coefficient is just for the pair average. The within-pair coefficient is identical to the β coefficient from a model that fits the absolute difference between the co-twins.22 Thus, the percent difference calculated from the within-pair coefficient can be interpreted as the difference in inflammatory biomarker concentrations per 1-unit absolute difference in the MDS between co-twins in a pair. Because twin pairs were raised together and MZ pairs share 100% of their genetic material, any association between the MDS and inflammatory markers within MZ pairs cannot be ascribed to genes or family environment. DZ pairs also share familial factors but on average share only 50% of their genetic material and as such are less tightly matched. These models included separated variance components for twin type to accommodate the different residual correlation in MZ and DZ pairs. MZ and DZ twins, however, also were examined separately. Obesity is tightly associated with systemic inflammation25; thus, we further examined whether the diet-inflammation association was different among obese versus nonobese (body mass index ≥30 versus <30 kg/m2) twins. All analyses were conducted with mixed models to control for the pair clustering using SAS software version 9.1 (SAS Institute). Significance levels were set at P=0.05 (2 sided).
The authors had full access to and take responsibility for the integrity of the data. All authors have read and agree to the manuscript as written.
From the initial sample of 360 twins, we excluded 15 subjects (1 with no dietary data, 6 with implausible energy intake, and 8 with plasma IL-6 levels >10 pg/mL). Therefore, our analyses were based on 345 twins (88 MZ and 77 DZ twin pairs, 5 MZ and 10 DZ unpaired twins). The sample was 94% non-Hispanic white, 3% black, and 3% other race/ethnic groups. This distribution reflected the racial distribution of the Vietnam Era Twin Registry from which it was sampled. The median biomarker concentration was 1.7 pg/mL (interquartile range, 1.1 to 2.7 pg/mL) for IL-6 and 1.3 mg/L (interquartile range, 0.5 to 2.7 mg/L) for hsCRP. Twins with higher MDS were older, more educated, less likely to be smokers, and more likely to use fish oil supplements (Table 1). The mean within-pair absolute difference in the MDS was 1.6 (range, 5) in MZ and 1.8 (range, 7) in DZ twins. Intraclass correlation coefficients for the MDS, IL-6, and hsCRP were larger in MZ than DZ twin pairs (Table 2), suggesting that genetic factors contribute to these traits.
Increasing MDS was associated with decreasing levels of IL-6 and hsCRP in a dose-response fashion (Table 3). When the MDS was treated as a continuous variable, for each 1-unit increase in the MDS, IL-6 and hsCRP levels decreased by 6.6% (P=0.001) and 5.6% (P=0.064), respectively, after adjustment for nutritional factors (Table 3). After simultaneous adjustment for known cardiovascular risk factors, the association between the MDS and hsCRP was no longer significant. However, even after full adjustment, the relationship between the MDS and IL-6 remained strong (model 4 in Table 3): A 1-unit increment in the MDS was associated with a 5.1% decrease in IL-6 concentration (P=0.005). Similar results were observed with the MDS as an ordinal variable, confirming the presence of a dose-response association (Table 3). In the fully adjusted model, twins in the highest MDS category had an IL-6 level that was 21.3% (95% CI, 6.9 to 33.8) lower than those in the lowest category, and there seemed to be a threshold effect: Subjects with a score ≥6 had lower IL-6 levels than those with a score <6.
For MZ pairs, a 1-unit within-pair absolute difference in the MDS was associated with an 8.6% (95% CI, 1 to 15) and a 7.7% (95% CI, 1 to 14) lower IL-6 level before and after adjustment for the other risk factors, respectively (Table 4). The IL-6 results for DZ twins were similar. Neither MZ nor DZ twin pairs showed significant within-pair associations for hsCRP. The interaction between within-pair differences in the MDS and zygosity was not significant (Table 4). The between-pair associations of the MDS with inflammatory markers were not significant for either IL-6 or hsCRP (P=0.9 for IL-6, P=0.5 for hsCRP in the fully adjusted model), suggesting that shared familial factors were not important.
Because inflammation is a strong correlate of obesity, we also examined whether the within-pair association between the MDS and inflammatory markers differed by obesity. The interaction between within-pair differences in the MDS and obesity was not significant for either IL-6 or hsCRP in the fully adjusted model for the entire sample and by zygosity status (all P>0.25).
Finally, we repeated the analyses after excluding subjects with a previous history of coronary heart disease and by using published variations of the MDS (MDS1, MDS2, and MDS3). The results were very similar and are not shown.
We found an inverse association between adherence to the Mediterranean diet and inflammation as measured by IL-6 that was independent of a wide range of known cardiovascular risk factors. This finding persisted when co-twins within pairs, either MZ or DZ, were compared, suggesting that shared familial factors do not confound the association between adherence to the Mediterranean diet and systemic inflammation as measured by IL-6. Results were robust and persisted after exclusion of persons with a previous history of coronary heart disease and when slight variations of the MDS were used.
Prior studies on the association between the Mediterranean diet and systemic IL-6 levels are limited. Inverse associations between adherence to the Mediterranean diet and IL-6 were reported in observational studies among healthy subjects3,4 and intermediate-6 or long-term5 randomized controlled trials among subjects at high risk for cardiovascular disease5,6 but not in a short-term trial among healthy individuals,26 perhaps as a result of a lack of sufficient time to observe potential effects.
Although previous studies adjusted for sociodemographic and cardiovascular risk factors, no study has accounted for familial or genetic influences that may be shared between adherence to the Mediterranean diet and inflammatory response. Heritable and familial determinants affect both inflammatory biomarkers27 and dietary behavior, including food preference,28 food consumption frequency,29 and perception of hunger.30 A variety of other unmeasured environmental and behavioral factors that twins share may confound the diet-inflammation association and provide spurious associations. However, by comparing twins within pairs, we found that the MDS and IL-6 association was not diminished, which points to the conclusion that genetic influences or other familial factors do not play major roles.
We found an independent association between adherence to the Mediterranean diet and plasma levels of IL-6 but not CRP. In the base model, CRP was marginally associated with the MDS (P=0.06), but after known cardiovascular risk factors were controlled for, this relationship was substantially reduced. Several studies have found that the association between CRP and cardiovascular disease is attenuated after adjustment for confounding factors.31–35 One possible explanation is that IL-6 is a more sensitive indicator of atherosclerosis and cardiovascular risk than CRP.36–39 IL-6 has numerous biological actions40 that may promote atherosclerosis, including regulation of immune cells, recruitment of lymphocytes via stimulation of endothelial synthesis of cellular adhesion molecules, procoagulant effects, and stimulation of the hepatic synthesis of CRP. Thus, IL-6 may have a direct atherogenic role,36,37,39,40 and CRP may serve mostly as a marker of IL-6 or other atherogenic risk factors.41
Although the within-pair effect was robust, the between-pair effect was weak and nonsignificant. This may be related to less confounding in the within-pair analyses. Because our twins were raised together, within-pair analyses naturally controlled for unmeasured confounding factors related to family environment or early development, which may act as negative confounders in this association. In general, a strong within-pair effect with a small or absent between-pair effect is consistent with a causal mechanism.22
There are some limitations to our study. The sample was restricted to middle-aged male Vietnam era veterans, and our results may not be generalizable to women. As in other common food frequency questionnaires used across the United States, combined food items, containing ≥2 components of the MDS, may misclassify individual MDS components. However, we carefully decomposed combined items into individual ingredients using appropriate recipes, therefore minimizing misclassification. Our results reflect only the cumulative effects of various foods in the MDS,42 and our findings should not be extrapolated to a single food component. As in all observational studies, our results may be affected by unmeasured confounding. However, we controlled for many known lifestyle factors and compared twins raised in the same family; thus, it is unlikely that other behavioral factors substantially confound the association between the MDS and inflammation.
Using a twin sample, we were able to demonstrate that shared environmental and genetic factors do not confound the association between adherence to the Mediterranean diet and systemic inflammation. Our findings add weight to the biological plausibility of the cardioprotective effect of the Mediterranean diet and substantiate the protective effect of the Mediterranean diet on cardiovascular risk. Furthermore, our data support the importance of behavioral interventions that encourage consumption of a healthier diet to prevent cardiovascular disease.
The Mediterranean diet is protective against cardiovascular disease; a proposed mechanism is through reducing systemic inflammation. Dietary habits are acquired while growing up and may be confounded by other behavioral, environmental, or genetic factors shared by family members. It is unknown to what extent the association between the Mediterranean diet and inflammation is due to other familial factors. We used data on identical and fraternal twins raised together to answer this question because twins are naturally matched for measured and unmeasured common environmental factors while growing up. Monozygotic twin pairs are also 100% matched for genetic factors, whereas fraternal pairs share on average 50% of their genes. We constructed a 10-unit diet score to measure adherence to the Mediterranean diet; a higher score indicates greater adherence to the Mediterranean diet. We found that a 1-unit increase in the Mediterranean diet score was associated with a 5% decrease in systemic inflammation measured by means of plasma interleukin-6 concentration. After further controlling for shared familial and genetic factors by examining differences between twins in a pair, we found that a twin with a 1-unit-higher Mediterranean diet score than his twin brother had a 9% lower interleukin-6 concentration. In contrast, shared familial and genetic factors did not significantly contribute to the association between MDS and inflammation. Our findings substantiate the protective role of the Mediterranean diet on cardiovascular risk and support the importance of consuming a healthier diet to prevent cardiovascular disease.
We gratefully acknowledge the continued cooperation and participation of the members of the Vietnam Era Twin Registry. Without their contribution, this research would not have been possible.
Sources of Funding
This work was supported by the National Institutes of Health (R01 HL68630, R01 AG026255, and K24HL077506 to Dr Vaccarino), the American Heart Association (0245115N to Dr Vaccarino and 0615123B to Dr Dai), and Emory University General Clinical Research Center (MO1-RR00039). The US Department of Veterans Affairs has provided financial support for the development and maintenance of the Vietnam Era Twin Registry. Numerous organizations have provided invaluable assistance, including the Veterans Affairs Cooperative Studies Program; Department of Defense; National Personnel Records Center, National Archives and Records Administration; Internal Revenue Service; National Institutes of Health; National Opinion Research Center; National Research Council, National Academy of Sciences; and Institute for Survey Research, Temple University.
The online Data Supplement can be found with this article at http://circ.ahajournals.org/cgi/content/full/CIRCULATIONAHA.107.710699/DC1.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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South Ogden Police investigating spray paint incident at home of two deputies
, South Ogden Police Department
SOUTH OGDEN — Police are investigating separate incidents of criminal mischief at the homes of two law enforcement officers.
Saturday morning, both a Weber County Sheriff's deputy and Davis County Sheriff's deputy found spray paint marring their homes and one officer's DARE vehicle, according to South Ogden police spokeswoman Marci Edwards. Both officers live in the same South Ogden neighborhood near 1200 East and 5800 South.
"The Davis County deputy had his DARE car parked outside on his driveway and … the entire exterior of the vehicle was spray-painted in black paint," Edwards said.
The vandal also left a message reading "(expletive) cops" in the driveway in front of the vehicle. The same message was discovered, also written in black spray paint, on the garage doors of a Weber County Sheriff's deputy who lived nearby.
That officer did not have any vehicles in his driveway. It doesn't appear any other homes or vehicles were targeted.
"We do believe that they left a mesage specific for law enforcement officers at the law enforcement officers' residences," Edwards said. "We do believe they know exactly who lives there."
In the DARE program, officers insturct students in kindergarten through 12th grade in the classroom on how to resist peer pressure and live productive drug and violence-free lives.
Edwards said the department is anxious to find those responsible. Anyone with information about the incident has been asked to call dispatch at 801-629-8221.
— Emiley Morgan Twitter: DNewsCrimeTeam
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Imperial Hotel Osaka
Imperial Hotel Osaka offers the atmosphere of flowers, foliage, and water highlighting its landscape. It is designed by Frank Lloyd Wright, located in the Osaka Amenity Park overlooking Kema Sakuranomiya Park.In spring the highlight of this riverside park is the blooming of cherryblossoms which draws throngs of admirers. In summer one of Japan's trio of festivals- Tenjin Matsuri- is held near the hotel affording guests the chance to experience a colorful uniquely Japanese celebration. Fine dining available at the famous French restaurant Les Saisons.
Hotel Address:Location Summary
- Imperial Hotel Osaka
- 8-50 Temmabashi 1-chome
- Kita-ku
- Osaka, 530
- Japan
Located Silent River Side Walking Distance To Oap Osaka Amenity Park.
Directions to Hotel
Directions From Airport To Hotel - * From Kansai International Airport Take Highway Wangan Lane To Ohgimachi. Exit Through Highway 12 Moriguchihi Lane. Go Straight. Turn Right At First Corner. Turn Right At The Crossing Of Gempachibashi Nishizume. Hotel Is 1 Block South On The Left. * From Osaka International Airport Take Highway 11 Ikeda Lane To South. Take Highway 12 Moriguchi Lane To Ohgimachi Exit. Go Straight. Turn Right At First Corner. Turn Right At The Crossing Of Gempachibashi Nishizume. Hotel Is 1 Block South On The Left.
Banquets & Meetings
The fifteen function rooms accommodate up to 2,000 people.
Business Center
One conference room.
Disabled Access
One room.
Fine Dining on Site
French, Chinese, and Japanese cuisines.
Child Programs
Hotel has Kid's Room with games and food.
Tennis Courts on Site
Three courts.
Riverboat located in front of hotel.
Golf Driving Range
Driving range is on the property.
Indoor golf green and driving range are on the property.
Recommended Rooms
The Imperial Suite is very nice and has two bedrooms. All suites overlook the river and a park known for its cherry blossoms. Additionally, some of the suites have rounded windows which offer a 180 degree view of the city.
Guest Review Highlights
58% (1231)
29% (615)
8% (170)
5% (106)
Hotel Amenities
- - Banquets & Meetings
- - Business Center
- - Disabled Access
- - Fine Dining on Site
- - Fitness Center
- - High Speed Internet
- - Child Programs
- - Pool, Indoor
- - Tennis Courts on Site
Available Activities
- - Boating
- - Golfing
- - Tennis Courts Nearby
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|Thematically Organized Assessment Tasks
Consortium for
A New Jersey FLAP Grant Project
What are the content/theme areas of the TOAs?
All of the Thematically Organized Assessments have been developed around a certain pre-identified theme. Many-if not all-of these themes are familiar to language teachers and language learners, although the particular title ascribed to the theme may use different wording that what is more commonly seen. The following themes have been used for development of the TOAs:
The TOAs are listed by level (novice, intermediate,
pre-advanced) and then identified by theme – title.
While each task has been developed in a specific
language, it is our belief that these tasks can easily
be adapted for other languages. Therefore, the language
of the TOA has not been identified in the listing in the
hopes that teachers will investigate all the TOAs,
regardless of the specific language they teach
What does a TOA actually look like?
Each TOA is anchored to a proficiency target
(Novice-Mid, Intermediate-Low or Pre-Advanced
[Intermediate-High]), a theme and the three modes of
communication (interpersonal, interpretive and
presentation). A list of TOA themes is provided in a
previous section of this introduction.
TOAs are intended to measure the full range of
student language ability across the three modes of
communication: interpretive, interpersonal, and
presentational. Therefore, each TOA, in addition to
targeting a proficiency level and a theme will assess
student communicative ability across the three modes.
Thus, each task contains a page with standard
template information that provides the using teacher
with the elements of the assessment task.


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An extremly fat pussy that no one wants to hit because it is so beefy and un-atractive
yo that chick over there most have the worst beef cunt ive ever seen.
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