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"Trouble Town," a classic rock group from Macon, performed during last week's Kirksville Arts Association Summer on the Square concert series event. This Friday at 7 p.m., "Redwing" will take the square with a set of country, bluegrass and Civil War music.
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Library JournalPeople love small indoor fountains for their pleasant, calming gurgle and the effect of bringing the outdoors inside. All that is required is a waterproof container, plastic tubing, and a submersible circulating pump. Add some decorative objects to hide the waterworks, and you have a fountain that is as self-contained as a lamp. This book outlines the basics of fountain materials and assembly and provides step-by-step projects by 12 designers. The materials are as ordinary as beach pebbles or as unusual as a recycled computer monitor. A delightful addition to craft or garden collections. Copyright 2000 Cahners Business Information.\
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Larry Turner and Kwame Brown - Larry Turner and Kwame Brown Hollywood, California - Derek Fisher celebrates his return to the Los Angeles Lakers basketball team at eat. on sunset Wednesday 17th October 2007
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Rachel Weisz is extremely moving. --The New Yorker
Rachel Weisz is incandescent. --Rolling Stone
Rachel Weisz is extremely moving. --The New Yorker
Rachel Weisz is incandescent. --Rolling Stone
Special Features
- Audio commentary
- Interviews with Rachel Weisz and Tom Hiddleston
- Terence Davies' Master Class
- Realizing the Director's Vision
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Customer Reviews
Top Customer Reviews
The film is simple in concept and quite cliched because it's been done 10 million times in films and theater and books. It's the classic love triangle. Sir William (Simon Russell Beale) loves Hester (Rachel Weisz) who doesn't love him but instead loves dashing Freddie (Tom Huddleston), who enjoys her body but doesn't love her. William is an intelligent, accomplished lawyer and mama's boy who married the well bred and very hot Hester but obviously is not a stud.
Hester, who hates the overbearing mama and lacks any spark at all in her personal relationship with Sir William, falls in love with a flirtatious hot stud fighter pilot Freddie (this is the 1950s in Britain when they were the equivalent of almost forgotten rock stars today). And falls into bed and there are a few nude scenes showing them coiling around each other in bed that explain the immediate physical attraction of both. You can't quite get your head around a mental vision of the older, rotund Sir William doing the nasty with the gorgeous Hester. Which explains why Hester is willing to walk away from a marriage to a man that brought her wealth and security and intellectual companionship for the heady hot love of a younger man.Read more ›
The film has an unusual structure that works well for the themes explored. It opens with Hester about to commit suicide, and recalling via flashback what transpired to get her to this point. Like true memories, they don't necessarily come in clearly, or in order, and it can be challenging for a viewer to follow at first. The movie is ostensibly about the affair between Hester and Freddie, but also subtly addresses the mystery of depression to those who have never experienced it, and cannot understand it. Hester's husband loves her; they have money and privilege, yet she is painfully unhappy because they are no more than friends. Along comes Freddie who, after surviving the Battle of Britain, is living life to the fullest with little thought for tomorrow - and she falls in love for the first time in her life. But, Freddie is unable to give her everything she needs either. It would have been easy to make Freddie the "villain" here, and I am glad the director did not. Freddie is insensitive and occasionally cruel to Hester. Yet, he never misled her on who he is, or what he could be for her. He is as trapped in his life as she in hers. One scene in the museum shows that she can be cruel to him in turn.Read more ›
This film is beautifully shot and staged, and the acting is well done. There, those are my only two positive comments. Now, to my criticisms.
As many others have mentioned, the shrieking, beyond melodramatic violin score through the initial scenes made me feel like I wanted to claw my skin off. Someone needs to instruct director Terence Davies that a film score is supposed to draw the audience IN to the story line, not make them wish to run for the nearest exit. We are introduced to the main character, Hester, as she is attempting suicide with every means at her disposal in her squalid post-war flat. In a mixture of flashbacks and real-time, we are shown the situations that supposedly brought her to this point.
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Most Recent Customer Reviews
Depressing. Horribly, stupidly depressing. Amazing description is the worst ever.Published 19 days ago by Rachel Benton
Not enough happens in this film. In addition to being painfully slow, we don't get much information. Read morePublished 1 month ago by librich
Tom Hiddleston as the lead's lover and supporting actor does a fine job in his portrayal although this is not often mentioned in reviews.Published 1 month ago by Hurrell
Too slow for my taste! I watched this because I like Tom Hiddleston(?) but even he couldn't save this.Published 1 month ago by Linda A
This movie started off a bit slow, but quickly builds intensity. Well worth the watch.Published 1 month ago by andyg


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Betty Pullen, 862-4844
Hello readers as always I hope everyone is well. Just a note to say thank you to all who supported the Sunflower Festival at Lakewood and Howevalley Days. I am sure both events went well.
BIRTHDAY WISHES. Happy birthday wishes to Brenda Hilton and Whitney Peters. My mother's birthday would have been Sept. 10 and she would have been 93 if she was still here. I guess you never forget the ones you love, no matter how long they're gone.
Debbie Owens and retired lieutenant colonel and Mrs. Donald Owens of Elizabethtown announce the engagement and forthcoming marriage of their daughter, Rebecca Owens of Elizabethtown, to Christopher Waggoner of Clarksville, Tenn., son of Jeanette Waggoner and retired Col. Chuck Waggoner of Magnolia.
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Steven and Elsa Gonzalez Sharlow of Radcliff will celebrate their 34th wedding anniversary Sept. 19, 2012.
They were married Sept. 19, 1978, in Canal Zone, Republic of Panama by a U.S. judge.
Mr. Sharlow is employed with Army civil service at Fort Knox and is a member of Church of God of Prophecy.
Mrs. Sharlow is employed at North Hardin High School and also is a member of Church of God of Prophecy.
They have two children, Jeremy Sharlow of Campbellsille and Aaron Sharlow of Columbia; and one granddaughter.
The Optimist Club of Radcliff welcomes new member Andrei Tunsil, center, who was sponsored by Maria Batistoni, right, club board director. Tunsil has been inducted by Lt. Governor of Zone 2 of the Kentucky and West Virginia District Willie Lee and presented a new member packet by president Mae Knight, left.
The City of Elizabethtown and E-town Tourism and Convention Burea recently thanked sponsors of Heartland Festival in the Park 2012 of the $5,000 level and higher, including First Federal Savings Bank, WAKY 103.5 & Big Cat WLVK, not pictured.
BAKER. Air Force Airman Matthew R. Baker graduated from basic military training at Lackland Air Force Base in San Antonio. A 2008 graduate of Central Hardin High School, he is the son of Dennis and Elizabeth Baker of Hodgenville.
AUMACK. Air Force Airman Steven M. Aumack graduated from basic military training at Lackland Air Force Base in San Antonio. A 2009 graduate of Eagle River High School in Eagle River, Ak., he is the son of Renee Pack of Rineyville.
During the Aug. 11 Second Saturday Downtown Elizabethtown event, JoAnn Winkenhofer, left, and Regina Lancaster, wear Woman's Club of Elizabethtown T-shirts and hand out maps and brochures for recycling and for special historical interests of the city. A Civil War drama also was being held at the Brown-Pusey House cosponsored with the Hardin County History Museum. Club members hared a tent with Winkenhofer's husband, Alan, who was grilling hot dots and bratwurst for guests at the event.
The Fort Knox Potted Few places a flower design or plant in a community public place each month to encourage the appreciation of the beauty of nature. Pictured are Potted Few Garden Club member Lahoma Baymor with Fort Knox Barr Library Director Michael Steinmacher. The next meeting is at 10 a.m. Sept. 19 at the home of Jean Janes in Elizabethtown with co-host Jane Tabacchi. Janes will provide a workshop about how to arrange flowers in a common container or vase. To attend, call Anneliese Knoll at 352-0484.
Mae Knight, center, president of the Optimist Club of Radcliff, presents Lonnie Dennis, along with his wife, Kim, a certificate of appreciation for being the guest speaker at the club meeting Aug. 28. Dennis is the new principal at North Hardin High School.
Copyright © 2016
The News-Enterprise is your source for local news, sports, events and information in Elizabethtown, KY, Hardin County and the surrounding area.


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|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|Peter Donald <dona...@apache.org>
|Re: Cannot delete jar files
|Wed, 08 Nov 2000 07:56:43 GMT
At 08:51 8/11/00 +0100, you wrote: >>>>>> "WS" == William Settle <email@example.com> writes: > > WS> I jar two sets of packages and for discussion sake, I'll call > WS> them a.jar and b.jar. Both files are included in my classpath > >[...] > > WS> After a successful build everything's fine unless I re-run the > WS> build. My "clean" target attempts to delete existing jars but > WS> fails with a message that says: > > WS> BUILD FAILED C:\autoBuild\build.xml:23: Unable to delete file > WS> D:\develop\jar\a.jar > >I think you will never be able to delete a file that is in the JVM's >CLASSPATH on Windows because the JVM locks it (and I vaguely remember >it won't release that lock even if you don't need the file). It will release it when all classes loaded from it are disposed of which means shutting down the classloader. But not all JVMs actually do proper garbage disposal ;( Cheers, Pete *------------------------------------------------------* | "Nearly all men can stand adversity, but if you want | | to test a man's character, give him power." | | -Abraham Lincoln | *------------------------------------------------------*
|View raw message


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God is Here!
By Joel Raney
To play the media you will need to update yourFlash plugin.
SATB choir and piano with optional unison choir, brass, percussion and 3-5 octave handbells
Composed by Joel Raney. General, Adults & Children, Stewardship, Worshiping, Hymntune. Octavo. 12 pages. Published by Hope Publishing Company (HP.C5791).
Item Number: HP.C5791
Text by Fred Pratt Green. Scriptural Reference: Matthew 18:20, Philippians 2:2; Words by Fred Pratt Green.
Fred Pratt Green's established hymn text is given a majestic, new musical treatment by arranger Joel Raney. Featuring parts for Children's Choir, Brass, Percussion and 3-5 oct. Handbells, this is a stirring exaltation of praise, bringing all of the musical forces together in worship to exclaim "God is here!".


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A Meta-Analysis of High Resolution Audio Perceptual Evaluation - June 2016
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Synthetic Reverberator - January 1960
3 comments
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AES E-Library
Measuring Equipment for the Estimation of "Pop" Sensitivity of Microphones
The generation of pops by human speech is not adequately reproducible for measurement purposes. Therefore standard test equipment and measuring methods had to be developed. The test equipment (a dynamic loudspeaker with a well-defined jet hole mounted in a plate) generates an air flow similar to human plosives in a reproducible manner. The reponse of the microphone under test is digitized and stored on a PC disk for further evaluation.
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Most Cited Multiple Sclerosis and Related Disorders Articles
The most cited articles published since 2011, extracted from Scopus.
Treatment of neuromyelitis optica: Review and recommendationsDorlan J. Kimbrough | Kazuo Fujihara | Anu Jacob | Marco A. Lana-Peixoto | Maria Isabel Leite | Michael Levy | Romain Marignier | Ichiro Nakashima | Jacqueline Palace | Jrme De Seze | Olaf Stuve | Silvia N. Tenembaum | Anthony Traboulsee | Emmanuelle Waubant | Brian G. Weinshenker | Dean M. Wingerchuk
Volume 1, Issue 4, October 2012, Pages 180-187
Neuromyelitis optica (NMO) is an autoimmune demyelinating disease preferentially targeting the optic nerves and spinal cord. Once regarded as a variant of multiple sclerosis (MS), NMO is now recognized to be a different disease with unique pathology and immunopathogenesis that does not respond to traditional MS immunomodulators such as interferons. Preventive therapy in NMO has focused on a range of immunosuppressive medications, none of which have been validated in a rigorous randomized trial. However, multiple retrospective and a few recent prospective studies have provided evidence for the use of six medications for the prevention of NMO exacerbations: azathioprine, rituximab, mycophenolate mofetil, prednisone, methotrexate and mitoxantrone. This review provides a comprehensive analysis of each of these medications in NMO and concludes with a set of recommended consensus practices. © 2012 Elsevier B.V.
Fingolimod in relapsing multiple sclerosis: An integrated analysis of safety findingsLudwig Kappos | Jeffrey Cohen | William Collins | Ana De Vera | Lixin Zhang-Auberson | Shannon Ritter | Philipp Von Rosenstiel | Gordon Francis
Volume 3, Issue 4, January 2014, Pages 494-504
Background Fingolimod 0.5 mg once daily is the first approved oral therapy for relapsing multiple sclerosis (MS). Objective To report integrated long-term safety data from phase 2/3 fingolimod studies. Methods Descriptive safety data are reported from the FTY720 Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis (FREEDOMS) study, a 24-month, randomized, double-blind study comparing fingolimod 0.5 mg and 1.25 mg with placebo, and an All Studies group (patients who received fingolimod 0.5 mg (n=1640) or 1.25-0.5 mg (n=1776) in phase 2/3 studies and associated extensions). Relevant post-marketing experience, up to December 2011, is included. Results The incidence of adverse events (AEs) and serious AEs (SAEs) was similar with fingolimod and placebo in FREEDOMS. In the All Studies group, fingolimod 0.5 mg was associated with transient, rarely symptomatic (0.5%), bradycardia and second-degree atrioventricular block on treatment initiation, minor blood pressure increases, frequent (9%) but generally asymptomatic liver enzyme elevations, and macular oedema (0.4%). The incidences of infections (including serious and herpes infections), malignancies, SAEs and treatment discontinuations due to AEs were similar with fingolimod 0.5 mg and placebo. Conclusion The safety profile of fingolimod has been well characterized in this large combined trial population. Although infrequent SAEs can occur, there is no increased risk of infections, malignancies or serious cardiovascular events versus placebo. © 2014 PublishedbyElsevierB.V.
Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouseSarah Al-Izki | Gareth Pryce | Janet K. O'Neill | Colin Butter | Gavin Giovannoni | Sandra Amor | David Baker
Volume 1, Issue 1, January 2012, Pages 29-38
Biozzi ABH mice develop a reproducible, relapsing-remitting form of experimental autoimmune encephalomyelitis (EAE) that becomes secondary progressive with disease duration. The relapses observed are T-cell dependent and can be inhibited by immune tolerance induction. In contrast the progressive neurodegeneration is T cell-independent and continues despite the re-induction of immune tolerance. Here we present a practical guide to EAE induction in the ABH mouse and approaches used to control relapses such that both autoimmune-independent and autoimmune-dependent mechanisms of neurodegeneration can be explored. Disease-related weight changes are associated with blood-brain barrier dysfunction and clinical disease. A new method for detecting neurodegeneration is described along with new experimental details that will aid in the undertaking of studies in EAE in mice, with particularly emphasis on ABH mice. © 2011 Elsevier B.V. All rights reserved.
First-dose effects of fingolimod: Pooled safety data from three phase 3 studiesJohn P. Dimarco | Paul O'Connor | Jeffrey A. Cohen | Anthony T. Reder | Lixin Zhang-Auberson | Dejun Tang | William Collins | Ludwig Kappos
Volume 3, Issue 5, January 2014, Pages 629-638
Fingolimod treatment initiation is associated with a transient slowing of heart rate and atrioventricular conduction. This report presents first-dose fingolimod effects (0.5 mg or 1.25 mg) on cardiac parameters using phase 3 FREEDOMS, FREEDOMS II and TRANSFORMS pooled study data (n=3635 patients). Vital signs were recorded hourly for ≥6 h; 12-lead electrocardiogram (ECG) was obtained at baseline and at 6 h post-dose. Clinical events were graded at the first-dose administrators discretion. At screening, on day 1 and at month 3, 1073 patients underwent 24-h ambulatory electrocardiogram monitoring. A transient decrease in mean measured heart rate occurred 4-5 h after the first dose, with a maximum reduction of 8 (fingolimod 0.5 mg) and 11 beats per minute (fingolimod 1.25 mg) below baseline. Symptomatic bradycardia at treatment initiation was reported in 0.6% (fingolimod 0.5 mg) and 2.1% (fingolimod 1.25 mg) of patients; events were typically mild or moderate in severity, and most resolved spontaneously. Atrioventricular (AV) conduction delays were observed in a few patients (Wenckebach (Mobitz type I) second-degree AV block, fingolimod 0.5 mg, 0.2%; 1.25 mg, 1%: 2:1 AV block fingolimod, 0.5 mg, 0%; 1.25 mg, 0.2% on ECG 6-h post-dose). These were usually well tolerated and first occurred within 6 h of dosing. Consistent with its effects on atrial myocytes, fingolimod treatment initiation induced a transient slowing of heart rate and AV conduction. However, symptomatic bradycardia and second-degree AV block were uncommon and did not require intervention. © 2014 Elsevier B.V.
Experimental in vivo and in vitro models of multiple sclerosis: EAE and beyondMarkus Kipp | Baukje Van Der Star | Daphne Y S Vogel | Fabiola Puentes | Paul Van Der Valk | David Baker | Sandra Amor
Volume 1, Issue 1, January 2012, Pages 15-28
Although the primary cause of multiple sclerosis (MS) is unknown, the widely accepted view is that aberrant (auto)immune responses possibly arising following infection(s) are responsible for the destructive inflammatory demyelination and neurodegeneration in the central nervous system (CNS). This notion, and the limited access of human brain tissue early in the course of MS, has led to the development of autoimmune, viral and toxin-induced demyelination animal models as well as the development of human CNS cell and organotypic brain slice cultures in an attempt to understand events in MS. The autoimmune models, collectively known as experimental autoimmune encephalomyelitis (EAE), and viral models have shaped ideas of how environmental factors may trigger inflammation, demyelination and neurodegeneration in the CNS. Understandably, these models have also heavily influenced the development of therapies targeting the inflammatory aspect of MS. Demyelination and remyelination in the absence of overt inflammation are better studied in toxin-induced demyelination models using cuprizone and lysolecithin. The paradigm shift of MS as an autoimmune disease of myelin to a neurodegenerative disease has required more appropriate models reflecting the axonal and neuronal damage. Thus, secondary progressive EAE and spastic models have been crucial to develop neuroprotective approaches. In this review the current in vivo and in vitro experimental models to examine pathological mechanisms involved in inflammation, demyelination and neuronal degeneration, as well as remyelination and repair in MS are discussed. Since this knowledge is the basis for the development of new therapeutic approaches for MS, we particularly address whether the currently available models truly reflect the human disease, and discuss perspectives to further optimise and develop more suitable experimental models to study MS. © 2011 Elsevier B.V. All rights reserved.
The CombiRx trial of combined therapy with interferon and glatiramer acetate in relapsing remitting MS: Design and baseline characteristicsJ. W. Lindsey | T. F. Scott | S. G. Lynch | S. S. Cofield | F. Nelson | R. Conwit | T. Gustafson | G. R. Cutter | J. S. Wolinsky | F. D. Lublin
Volume 1, Issue 2, April 2012, Pages 81-86
Background: Interferon-β1a (IFNB) and glatiramer acetate (GA) are distinct therapies which are both partially effective for relapsing MS. It is not known if combining the two treatments would be more effective. Objective: To review the rationale, design, and baseline characteristics of the CombiRx study of combined treatment with IFNB and GA. Methods: The key inclusion criteria included a diagnosis of relapsing MS, at least 2 episodes of MS activity in the previous 3 years, expanded disability status scale of 05.5, and no prior treatment with either IFNB or GA. Subjects were randomized to IFNBGA, IFNB monotherapy, or GA monotherapy in a 2:1:1 ratio. Results: From 2005 to 2009, we enrolled 1008 subjects. The participants were 72.4% female and 87.6% Caucasian with a mean age of 37.7 years. The median duration of symptoms was 2 years at entry into the study, and the mean EDSS was 2.1. On the baseline MRI, the mean total lesion load was 12.2 ml, and 40% of the participants had enhancing lesions. Conclusion: We have recruited a population of patients with clinical and MRI characteristics typical for early MS. The study results will aid in deciding on the optimum early treatment. This trial should serve as a model for future studies of combination therapy. © 2012 Elsevier B.V.
Moving toward earlier treatment of multiple sclerosis: Findings from a decade of clinical trials and implications for clinical practiceMark S. Freedman | Giancarlo Comi | Nicola De Stefano | Frederik Barkhof | Chris H. Polman | Bernard M J Uitdehaag | Lorenz Lehr | Bettina Stubinski | Ludwig Kappos
Volume 3, Issue 2, March 2014, Pages 147-155
The first clinical presentation of multiple sclerosis (MS) is usually a single episode of typical symptoms and signs and is designated a "first clinical demyelinating event" (FCDE) or a "clinically isolated syndrome". Patients with an FCDE who show 'silent' magnetic resonance imaging lesions are at high risk of further clinical events and therefore of meeting the criteria for the diagnosis of clinically definite MS (CDMS). Here we review five Phase III trials, in which treatment with the following disease-modifying drugs (DMDs) was initiated at this early stage: interferon beta (ETOMS, CHAMPS, BENEFIT, and REFLEX) and glatiramer acetate (PreCISe). Differences in the design of the trials and their patient inclusion criteria limit comparisons. However, the proportion of placebo-treated patients who developed CDMS within 2 years was 38-45% across studies, and this rate was significantly reduced by DMD treatment. Conversion to McDonald MS was reported by only two of the trials: BENEFIT (2001 criteria) and REFLEX (2005 criteria). Around 85% of placebo-treated patients developed McDonald MS by 2 years in each, and again a beneficial effect of DMD treatment was seen. Overall, these studies support early use of DMDs to treat patients with an FCDE who are at high risk of conversion to CDMS. © 2013 The Authors.
Prevalence and incidence of ischemic heart disease in multiple sclerosis: A population-based validation studyRuth Ann Marrie | Bo N. Yu | Stella Leung | Lawrence Elliott | Patricia Caetano | Sharon Warren | Christina Wolfson | Scott B. Patten | Lawrence W. Svenson | Helen Tremlett | John Fisk | James F. Blanchard
Volume 2, Issue 4, October 2013, Pages 355-361
Background Studies suggest an altered risk of ischemic heart disease (IHD) in multiple sclerosis (MS), but data are limited. We aimed to validate and apply administrative case definitions to estimate the incidence and prevalence of IHD in MS. Methods Using administrative data we identified persons with incident MS (MSPOP) and a matched general population (GPOP) cohort. We developed case definitions for IHD using ICD-9/10 codes and prescription claims, compared them to medical records, then applied them to evaluate the incidence and prevalence of IHD. Results Agreement between medical records and the administrative definition using ≥1 hospital or ≥2 physician claims over 5 years was moderate (kappa=0.66; 95% CI: 0.42-0.90). In 2005, the age-standardized prevalence of IHD was 6.77% (95% CI: 5.48-8.07%) in the MSPOP and 6.11% (95% CI: 5.56-6.66%) in the GPOP. The prevalence of IHD was higher in the MSPOP than the GPOP among persons aged 20-44 years (prevalence ratio 1.87; 95% CI: 1.65-2.12) and aged 45-59 years (prevalence ratio 1.21; 95% CI: 1.08-1.35). The incidence of IHD was also higher in the MSPOP (incidence rate ratio 1.24; 95% CI: 0.97-1.59). Conclusions More than 5% of the MSPOP has IHD. The incidence of IHD was higher than expected in persons aged <60 years. Further evaluation of this issue is warranted. © 2013 Elsevier B.V.
Is it time to target no evident disease activity (NEDA) in multiple sclerosis?Gavin Giovannoni | Benjamin Turner | Sharmilee Gnanapavan | Curtis Offiah | Klaus Schmierer | Monica Marta
Volume 4, Issue 4, January 2015, Pages 329-333
© 2015 The Authors.The management of multiple sclerosis is becoming increasingly complex with the emergence of new and more effective disease-modifying therapies (DMT). We propose a new treatment paradigm that individualises treatment based on a choice between two interchangeable therapeutic strategies of maintenance-escalation or induction therapy. We propose treating- to-target of no evident disease activity (NEDA) as defined using clinical and MRI criteria. This algorithm requires active monitoring with a rebaselining MRI, at a point in time after the specific DMT concerned has had sufficient time to work, and at least annual MRI studies to monitor for subclinical relapses. Disease activity on the maintenance-escalation therapy arm of the algorithm indicates a sub-optimal treatment response and should trigger a discussion about switching, or escalating, therapy or the consideration of switching to the induction therapy arm of the algorithm. In comparison, disease activity on an induction therapy arm would be an indication for retreatment or a switch to the maintenance-escalation therapy arm. We envisage the definition of NEDA evolving with time as new technological innovations are adopted into clinical practice, for example the normalisation of whole, or regional, brain atrophy rates and cerebrospinal fluid neurofilament levels
Persistence of the effects of attention and executive functions intensive rehabilitation in relapsing remitting multiple sclerosisF. Mattioli | C. Stampatori | C. Scarpazza | G. Parrinello | R. Capra
Volume 1, Issue 4, October 2012, Pages 168-173
Background: Neuropsychological rehabilitation efficacy in multiple sclerosis (MS) is a currently investigated issue. We reported, in a single blind controlled study, that an intensive short duration cognitive training of attention and executive functions significantly improves the treated functions and reduces depression in MS. The persistence of these effects over time are unknown. Objective: To evaluate the persistence over time of neuropsychological improvement due to cognitive training nine months after rehabilitation onset. Methods: This is a single blind randomized controlled study. 24 MS patients were randomly assigned to experimental group (n=13) and received PC assisted neuropsychological treatment for three months, or to control group (n=11), receiving no treatment. Patients were submitted to neuropsychological evaluation, depression and quality of life questionnaires at baseline, three months and nine months later. Results: Nine months follow up compared to baseline evaluation shows a statistically significant improvement (p<0.05) in attention, information processing and executive functions tests (PASAT 3″, COWA/S, WCSTpe), in depression and quality of life questionnaires in rehabilitated patients only. reliable change index (RCI) and modified RCI confirmed the clinical significance of this improvement in rehabilitated patients. Conclusions: Three months intensive neuropsychological rehabilitation of attention, information processing and executive functions induces a long lasting and clinically relevant neuropsychological improvement over time and a persistent depression and quality of life amelioration in patients with RR MS. © 2012 Elsevier B.V.
Cognitive and neuropsychiatric disease manifestations in MSA. Feinstein | J. Deluca | B. T. Baune | M. Filippi | H. Lassman
Volume 2, Issue 1, January 2013, Pages 4-12
Multiple sclerosis is associated with a wide array of behavioral problems. This brief overview begins with a summary of the pathophysiology and treatment of MS. Thereafter, sections are devoted to psychiatric syndromes and cognitive decline linked to MS. The immune basis and brain imaging data associated with these changes are subsequently reviewed. The frequency and severity of these changes in mentation highlight the point that MS patients should, as part of their routine care, have access to psychiatrists, neuropsychologists and allied mental health specialists. © 2012 Elsevier B.V.
A pilot MRI study of white and grey matter involvement by multiple sclerosis spinal cord lesionsH. Kearney | K. A. Miszkiel | M. C. Yiannakas | O. Ciccarelli | D. H. Miller
Volume 2, Issue 2, April 2013, Pages 103-108
Objectives: Spinal cord pathology is a major cause of disability in multiple sclerosis (MS) and pathology studies show multifocal demyelinating lesions in white matter (WM) tracts and central grey matter (GM). Better localisation of cord lesions by in vivo MRI may help to understand the structural-functional effects of spinal cord pathology in MS. Methods: Three-Tesla MRI was performed on upper cervical cord in 15 MS patients and one clinically isolated syndrome. Axial 3D gradient-echo fast field echo (3D-FFE) and phase sensitive inversion recovery sequences (3D-PSIR) were acquired. Two readers reviewed images to detect and classify lesions: WM-only, mixed WM-GM or GM-only. Location of the WM component was classified: anterior (AC), lateral (LC) or posterior (PC) column. Results: Fifty one lesions were identified: 32 (63%) mixed WM-GM, 19 (37%) WM-only, no GM-only. Most were in LC (n=30, 59%), followed by PC (n=18, 35%) and AC (n=3, 6%). Mean lesion areas: AC 4.3 mm 2, LC 8.5 mm2, PC 11.3 mm2, corresponding to 6.1%, 12% and 16.1% of mean cord area, respectively. Mean lesion lengths: 18.3 mm in AC, LC 17.6 mm and PC 24.8 mm. Conclusions: While there was good depiction of WM tract involvement by cord lesions, involvement of central grey matter was not as clear. Noting the important effects of spinal cord pathology in MS, further work to better depict cord lesions by in vivo imaging is warranted. © 2012 Elsevier B.V. All rights reserved.
The biology that underpins the therapeutic potential of cannabis-based medicines for the control of spasticity in multiple sclerosisDavid Baker | Gareth Pryce | Samuel J. Jackson | Chris Bolton | Gavin Giovannoni
Volume 1, Issue 2, April 2012, Pages 64-75
Cannabis-based medicines have recently been approved for the treatment of pain and spasticity in multiple sclerosis (MS). This supports the original perceptions of people with MS, who were using illegal street cannabis for symptom control and pre-clinical testing in animal models of MS. This activity is supported both by the biology of the disease and the biology of the cannabis plant and the endocannabinoid system. MS results from disease that impairs neurotransmission and this is controlled by cannabinoid receptors and endogenous cannabinoid ligands. This can limit spasticity and may also influence the processes that drive the accumulation of progressive disability. © 2011 Elsevier B.V.
Outcomes of switching directly to oral fingolimod from injectable therapies: Results of the randomized, open-label, multicenter, Evaluate Patient OutComes (EPOC) study in relapsing multiple sclerosisEdward Fox | Keith Edwards | Gordon Burch | Daniel R. Wynn | Chris Laganke | Heidi Crayton | Samuel F. Hunter | Cynthia Huffman | Edward Kim | Linda Pestreich | Kevin McCague | Luigi Barbato
Volume 3, Issue 5, January 2014, Pages 607-619
Background The Evaluate Patient OutComes (ClinicalTrials.gov Identifier: NCT01216072) study was conducted in North America to assess patient- and physician-reported treatment satisfaction in patients with relapsing multiple sclerosis (MS) who received oral fingolimod for 6 months after switching from an injectable disease-modifying therapy (iDMT), without an intervening washout. Methods In this open-label, multicenter study, patients were randomized 3:1 to once-daily fingolimod 0.5 mg or iDMT. The primary study objective was to evaluate differences in satisfaction measured using the Treatment Satisfaction Questionnaire for Medication v1.4. Results Of 1053 patients randomized, 790 patients received fingolimod and 263 patients received iDMT. Treatment satisfaction improved significantly in patients who switched to fingolimod compared with those who continued iDMT. Patients also reported significant improvements in health-related quality of life, reduced depression, and reduced fatigue severity after a switch to fingolimod. No difference between the treatment groups was detected on the Patient Reported Indices for MS Activities scale. The safety profile of fingolimod was consistent with that reported in the pivotal phase 3 studies. The most commonly reported adverse events were more prevalent in patients who switched to fingolimod than in those who continued iDMT (headache: 12% vs 3%; fatigue: 12% vs 6%). No significant relationship between lymphocyte counts and infection rates was observed and there was no evidence of additive immune-system effects, which might be expected when switching to a different class of immunomodulatory therapy with no intervening washout. Conclusion Patients who switched from iDMT to fingolimod had significant improvements in most self-reported outcomes compared with those who continued iDMT. © 2014 Elsevier B.V.
The effect of daclizumab on brain atrophy in relapsing-remitting multiple sclerosisIsabela T. Borges | Colin D. Shea | Joan Ohayon | Blake C. Jones | Roger D. Stone | John Ostuni | Navid Shiee | Henry McFarland | Bibiana Bielekova | Daniel S. Reich
Volume 2, Issue 2, April 2013, Pages 133-140
Daclizumab is a monoclonal antibody that reduces inflammation in multiple sclerosis (MS). Through a retrospective analysis, our objective was to determine whether daclizumab treatment reduces the rate of brain structure atrophy in comparison to a mixture of other disease-modifying therapies (mainly different interferon β preparations). We analyzed MRI examinations (1332 scans from 70 MS cases) obtained between 2000 and 2011 in a single center and processed with an automated brain segmentation method. We used mixed-effects multivariable linear regression models to determine whether a median of 4.3 years of daclizumab therapy in 26 patients altered rates of brain-volume change, controlling for variations in MRI protocol. The control group consisted of 44 patients not treated with daclizumab. We found that supratentorial brain volume declined by 5.17 ml per year (95% confidence limits: 3.58-6.77) off daclizumab therapy. On daclizumab, the annual rate of volume loss decreased to 3.72 ml (p=0.01). The rate of ventricular enlargement decreased from 1.26 to 0.42 ml per year (p<0.001). Focused analysis suggests that reduction in gray matter atrophy rate most likely underlies these results. In summary, in this retrospective analysis, daclizumab therapy substantially decreased the rate of brain atrophy in relapsing-remitting MS in comparison to other disease-modifying therapies, predominantly interferon β. © 2012 Elsevier B.V. All rights reserved.
Burden of multiple sclerosis on direct, indirect costs and quality of life: National US estimatesJonathan D. Campbell | Vahram Ghushchyan | R. Brett McQueen | Sharon Cahoon-Metzger | Terrie Livingston | Timothy Vollmer | John Corboy | Augusto Miravalle | Teri Schreiner | Victoria Porter | Kavita Nair
Volume 3, Issue 2, March 2014, Pages 227-236
Background MS imposes a significant burden on patients, caregivers, employers, and the healthcare system. Objective To comprehensively evaluate the US MS burden using nationally representative data from the Medical Expenditure Panel Survey. Methods We identified non-institutionalized patients aged ≥18 with MS (ICD-9 code 340) from 1998 to 2009 and compared them to individuals without an MS diagnosis (non-MS) during the interview year. The cohorts were compared using multivariate regression on direct costs, indirect costs (measured in terms of employment status, annual wages, and workdays missed), and health-related quality of life (HRQoL; measured using Short Form 12, SF-6 Dimensions, and quality-adjusted life years [QALYs]). Results MS prevalence was 572,312 (95% CI: 397,004, 747,619). Annual direct costs were $24,327 higher for the MS population (n=526) vs. the non-MS population (n=270,345) (95% CI: $22,320, $26,333). MS patients had an adjusted 3.3-fold (95% CI: 2.4, 4.5) increase in the odds of not being employed vs. non-MS individuals and a 4.4-fold higher adjusted number of days in bed (95% CI 2.97, 6.45). On average, MS patients lost 10.04 QALYs vs. non-MS cohort. Conclusions MS was associated with higher healthcare costs across all components, reduced productivity due to unemployment and days spent in bed, and lower HRQoL. © 2013 The Authors. Published by Elsevier B.V. All rights reserved.
Survival in commercially insured multiple sclerosis patients and comparator subjects in the U.S.D. W. Kaufman | S. Reshef | H. L. Golub | M. Peucker | M. J. Corwin | D. S. Goodin | V. Knappertz | D. Pleimes | G. Cutter
Volume 3, Issue 3, January 2014, Pages 364-371
Objective: Compare survival in patients with multiple sclerosis (MS) from a U.S. commercial health insurance database with a matched cohort of non-MS subjects. Methods: 30,402 MS patients and 89,818 non-MS subjects (comparators) in the OptumInsight Research (OIR) database from 1996 to 2009 were included. An MS diagnosis required at least 3 consecutive months of database reporting, with two or more ICD-9 codes of 340 at least 30 days apart, or the combination of 1 ICD-9-340 code and at least 1 MS disease-modifying treatment (DMT) code. Comparators required the absence of ICD-9-340 and DMT codes throughout database reporting. Up to three comparators were matched to each patient for: age in the year of the first relevant code (index year - at least 3 months of reporting in that year were required); sex; region of residence in the index year. Deaths were ascertained from the National Death Index and the Social Security Administration Death Master File. Subjects not identified as deceased were assumed to be alive through the end of 2009. Results: Annual mortality rates were 899/100,000 among MS patients and 446/100,000 among comparators. Standardized mortality ratios compared to the U.S. population were 1.70 and 0.80, respectively. Kaplan-Meier analysis yielded a median survival from birth that was 6 years lower among MS patients than among comparators. Conclusions: The results show, for the first time in a U.S. population, a survival disadvantage for contemporary MS patients compared to non-MS subjects from the same healthcare system. The 6-year decrement in lifespan parallels a recent report from British Columbia. © 2013 Elsevier B.V. All rights reserved.
Web search behavior for multiple sclerosis: An infodemiological studyFrancesco Brigo | Piergiorgio Lochner | Frediano Tezzon | Raffaele Nardone
Volume 3, Issue 4, January 2014, Pages 440-443
Objective Millions of people worldwide use the Internet daily as a source of health information. Google is the most popular search engine and is used by patients and physicians to search for online health-related information. This study aimed to evaluate changes in Web search behavior occurring in English-speaking countries over time for the term "multiple sclerosis" (MS). Methods Using Google Trends, data on global search queries for the term "multiple sclerosis" between January 2004 and December 2013 were analyzed. Results Over time there was a reduction in tendency to search for the term "multiple sclerosis". Most terms associated with the search queries for MS were related to causes and symptoms (including pain) of the disease, and most peaks in search volume over the period studied corresponded to news of celebrities having MS. Conclusions Most people appear to use search engines to look for MS to obtain information on symptoms, possibly to aid initial self-diagnosis. News on celebrities with MS seem to be a major factor that influences online search behavior. © 2014 Elsevier B.V.
High doses of biotin in chronic progressive multiple sclerosis: A pilot studyFrédéric Sedel | Caroline Papeix | Agnès Bellanger | Valérie Touitou | Christine Lebrun-Frenay | Damien Galanaud | Olivier Gout | Olivier Lyon-Caen | Ayman Tourbah
Volume 4, Issue 2, January 2015, Pages 159-169
© 2015 The Authors. Published by Elsevier B.V.Background No drug has been found to have any impact on progressive multiple sclerosis (MS). Biotin is a vitamin acting as a coenzyme for carboxylases involved in key steps of energy metabolism and fatty acids synthesis. Among others, biotin activates acetylCoA carboxylase, a potentially rate-limiting enzyme in myelin synthesis. Objectives The aim of this pilot study is to assess the clinical efficacy and safety of high doses of biotin in patients suffering from progressive MS. Study design Uncontrolled, non-blinded proof of concept study Methods 23 consecutive patients with primary and secondary progressive MS originated from three different French MS reference centers were treated with high doses of biotin (100-300 mg/day) from 2 to 36 months (mean=9.2 months). Judgement criteria varied according to clinical presentations and included quantitative and qualitative measures. Results In four patients with prominent visual impairment related to optic nerve injury, visual acuity improved significantly. Visual evoked potentials in two patients exhibited progressive reappearance of P100 waves, with normalization of latencies in one case. Proton magnetic resonance spectroscopy (H-MRS) in one case showed a progressive normalization of the Choline/Creatine ratio. One patient with left homonymous hemianopia kept on improving from 2 to 16 months following treatment's onset. Sixteen patients out of 18 (89%) with prominent spinal cord involvement were considered as improved as confirmed by blinded review of videotaped clinical examination in 9 cases. In all cases improvement was delayed from 2 to 8 months following treatment's onset. Conclusions These preliminary data suggest that high doses of biotin might have an impact on disability and progression in progressive MS. Two double-blind placebo-controlled trials are on going.
Managing flushing and gastrointestinal events associated with delayed-release dimethyl fumarate: Experiences of an international panelJ. Theodore Phillips | Michael Hutchinson | Robert Fox | Ralf Gold | Eva Havrdova
Volume 3, Issue 4, January 2014, Pages 513-519
Strategies for monitoring and managing the known adverse event (AE) profile of therapies for relapsing-remitting multiple sclerosis have become key to the optimization of patient outcomes. Delayed-release dimethyl fumarate (DMF) was associated with an increased risk of flushing and gastrointestinal (GI) AEs in clinical trials. A survey of clinicians with significant research experience using delayed-release DMF was conducted to provide guidance to clinicians using delayed-release DMF in clinical practice on the management of flushing and GI tolerability AEs. Recommendations for prophylaxis included educating the patient about flushing and GI AEs associated with delayed-release DMF and recommending administration with food. A variety of symptomatic treatments were utilized during the delayed-release DMF clinical trials in patients presenting with delayed-release DMF-related flushing or GI AEs that were severe or bothersome enough to warrant pharmacological intervention. © 2014 The Authors.
The effect of dimethyl fumarate (Tecfidera™) on lymphocyte counts: A potential contributor to progressive multifocal leukoencephalopathy riskBhupendra O. Khatri | Jeffery Garland | Joseph Berger | John Kramer | Lisa Sershon | Tayo Olapo | Jean Sesing | Mary Dukic | Eileen Rehn
Volume 4, Issue 4, July 2015, Pages 377-379
© 2015 Published by Elsevier B.V.Dimethyl fumarate (Tecfidera™) is an effective therapy for relapsing forms of multiple sclerosis (MS). Our study suggests that this drug may have immunosuppressive properties evidenced by significant sustained reduction in CD8 lymphocyte counts and, to a lesser extent, CD4 lymphocyte counts. This observation is relevant in light of the recent case of progressive multifocal leukoencephalopathy in a patient receiving this drug.
Case report of anti-glomerular basement membrane disease following alemtuzumab treatment of relapsing-remitting multiple sclerosisDavid Meyer | Alasdair Coles | Pedro Oyuela | Annie Purvis | David H. Margolin
Volume 2, Issue 1, January 2013, Pages 60-63
Objective: To report a case of anti-glomerular basement membrane disease (anti-GBM disease) during alemtuzumab treatment of a relapsing-remitting multiple sclerosis (RRMS) patient. Design: Case report. Setting: Outpatient neurology research protocol. Patient: A 35-year-old white female receiving alemtuzumab for RRMS in a clinical research protocol developed symptoms leading to diagnosis of anti-GBM disease. Main outcome measure: Patient response to the treatment of anti-GBM disease and RRMS. Results: Early identification and treatment of anti-GBM disease resolved clinical symptoms and preserved renal function. Alemtuzumab treatment of RRMS resolved initial MS symptoms and appears to have controlled active disease to date. Conclusion: Close monitoring for potential side effects of alemtuzumab treatment in RRMS resulted in a positive outcome when anti-GBM disease was recognized and treated early. © 2012 Elsevier B.V.
Human placenta-derived cells(pda-001) for the treatment of adults with multiple sclerosis: Arandomized,placebo-controlled, multiple-dose studyFred D. Lublin | James D. Bowen | John Huddlestone | Marcelo Kremenchutzky | Adam Carpenter | John R. Corboy | Mark S. Freedman | Lauren Krupp | Corri Paulo | Robert J. Hariri | Steven A. Fischkoff
Volume 3, Issue 6, January 2014, Pages 696-704
© 2014 Elsevier B.V. All rights reserved.Background: Infusion of PDA-001, a preparation of mesenchymal-like cells derived from full- Term human placenta, is a new approach in the treatment of patients with multiple sclerosis. Objective: This safety study aimed to rule out the possibility of paradoxical exacerbation of disease activity by PDA-001 in patients with multiple sclerosis. Methods: This was a phase 1b, multicenter, randomized, double-blind, placebo-controlled, 2- dose ranging study including patients with relapsing-remitting multiple sclerosis or secondary progressive multiple sclerosis. The study was conducted at 6 sites in the United States and 2 sites in Canada. Patients were randomized 3:1 to receive 2 low-dose infusions of PDA-001 (150 x 106 cells) or placebo, given 1 week apart. After completing this cohort, subsequent patients received high-dose PDA-001 (600 x 106 cells) or placebo. Monthly brain magnetic resonance imaging scans were performed. The primary end point was ruling out the possibility of paradoxical worsening of MS disease activity. This was monitored using Cutter's rule (> 5 new gadolinium lesions on 2 consecutive scans) by brain magnetic resonance imaging on a monthly basis for six months and also the frequency of multiple sclerosis relapse. Results: Ten patients with relapsing-remitting multiple sclerosis and 6 with secondary progressive multiple sclerosis were randomly assigned to treatment: 6 to low-dose PDA-001, 6 to high-dose PDA-001, and A to placebo. No patient met Cutter s rule. One patient receiving high-dose PDA-001 had an increase in T2 and gadolinium lesions and in Expanded Disability Status Scale score during a multiple sclerosis flare 5 months after receiving PDA-001. No other patient had an increase in Expanded Disability Status Scale score >0.5, and most had stable or decreasing Expanded Disability Status Scale scores. With high-dose PDA-001, 1 patient experienced a grade 1 anaphylactoid reaction and 1 had grade 2 superficial thrombophlebitis. Other adverse events were mild to moderate and included headache, fatigue, infusion site reactions, and urinary tract infection. Conclusion: PDA-001 infusions were safe and well tolerated in relapsing-remitting multiple sclerosis and secondary progressive multiple sclerosis patients. No paradoxical worsening of lesion counts was noted with either dose.
Disease activity free status in MSFred D. Lublin
Volume 1, Issue 1, January 2012, Pages 6-7
Neurological comorbidity and survival in multiple sclerosisOlga Krökki | Risto Bloigu | Hanna Ansakorpi | Mauri Reunanen | Anne M. Remes
Volume 3, Issue 1, January 2014, Pages 72-77
Objective There is increasing interest in the survival of multiple sclerosis (MS). MS itself may decrease life expectancy; however, several other comorbid diseases may also influence survival. We aimed to evaluate frequency of other neurological conditions and survival in the population-based Finnish Northern Ostrobothnia MS cohort. Methods The frequencies of neurological comorbid diseases and their associations with gender, clinical course, disability level (EDSS) and duration of MS were evaluated in population based cohort of 491 patients with clinically definite MS that was diagnosed between 1990 and 2010. The survival rate of the patients was also analysed. Results One or more neurological comorbid disease was present in 17.1% of patients (n=84). The prevalence of epilepsy in MS patients was 4.7%, which is greater than that in the general population. Migraine was significantly more common in women with a benign MS course when compared to other types of MS (p=0.046). A significant association between peripheral nervous system disorders and primary progressive MS was found (p=0.027). The 21-year survival rate from time of diagnosis was 90.5%. Stroke decreased the 21-year survival rate of the patients (p=0.003). An association between stroke prevalence and the duration of MS disease was also detected (p=0.023). Conclusions This is the first report of multifaceted neurological comorbidities in MS patients. Neurological comorbidity is rather common in MS. However, only the prevalence of epilepsy was increased in MS patients compared to the general population. An association between peripheral nervous system disorders and primary progressive MS was also found. The 21-year survival rate was greater in the present population based cohort compared in other studies, but stroke seems to decrease the survival rate in MS patients. © 2013 Elsevier B.V.


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About hurricaneben
Will devote this hurricane season to provide up-to-the-minute, basic information when a tropical system is threatening land. Both basins included.
By: hurricaneben , 1:55 AM GMT on August 13, 2011
We now have Tropical Depression Six from 94L to the north of Bermuda. This might slightly intensity further possibly into a minimal tropical storm before being absorbed by a front sometime tomorrow morning as it races out to sea. No land masses should feel any decent effects from this weak system so there is no need for anyone to be concerned about this one.
Invest 92L
Invest 92L has suffered from a slight decrease in organization today but conditions are still favorable for gradual development as it drifts well east of the Northern Lesser Antilles and turn away from the Caribbean and Lower 48 in the general direction of Bermuda. It has a 40% chance of TC formation by Sunday evening and I think we might see this become a TD at the very least sometime this weekend and a few models even made this a decent hurricane which I don't think is such an unlikely possibility. There is no threat to land in the near term but Bermuda may have to monitor this system just in case next week. However it doesn't appear like a major threat to at least the Lower 48 in the foreseeable future.
Invest 93L
Invest 93L is struggling right now as it is supposed to remain under unfavorable upper-level winds for the next day or two but after that it might really get its act together as it drifts into warmer waters on its track toward the Northern Lesser Antilles. This is the greatest threat to land and this might even enter the Caribbean next week as a tropical storm or hurricane. The NHC gives this a 30% chance of TC formation by Sunday evening. The threat to the CONUS is highly unclear at this time and there remains a chance that some part of the United States Mainland Coast may be greatly affected by this system whether it's the Gulf Coast, Florida or East Coast. Where remains to be seen.
Invest 94L
This one located well NE of Puerto Rico is steadily organizing and we might see something try to form from this in the next couple of days as it tugs westward than sharply recurve generally towards Bermuda. A few models make this certainly a healthy named system and perhaps close to hurricane strength at peak. This might be a concern for Bermuda and then maybe not, models generally take it either over the island or well east of the island. The NHC gives this a 30% chance of TC formation by Sunday evening.
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text: 5g19 Play via YouTube OPEN IN APP NSFW Safe Is this playlist safe for work? Leaking Face November 26, 2011 | 12 tracks | 58 2 | Stats Bulbous CreationArthur RussellDorothy Love Coates psychedelic rockalternative rockfunk/soul/rnb Liked Collect Share Edit Liked! Share this mix with friends: Leaking Face Wrong video Collect Share Liked! Share this mix with friends:


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eugene carl kotelman is a scam artest and a nark read this greene ounty
Posted in the Greeneville Forum
#1 Oct 26, 2010
mr eugene kotelman is living right here in greeneville tennessee actually right on 2410 joansbridge rd and drives 2 orange and black f150/250 harly edition trucks with white trash m.c. on the winshield hes been robbing everyone blind and most dont even know it alot of you reading this its proablly happened to you as well this peice of shit takes peoples information and files tax returns and has all the money direct deposited into private accounts and then closes them he puts up a front with a fake name gene dewitt he says he has a moving company and moves people off air bases lie lie lie he has people fill out job apps and then youll never see him again thatsall he needs your name social sec number date of birth and your address fer the last two years if this has happened to you comment on this and if you think this has happened to someone you know or someone who has recently filled out a app for a moving company to move people off military bases gene your going down and im allowing everyone around you that youve fucked over your name you deserve everything you got comming to you now your wanted in five states everyone go google him...lets get this asshole outta our city or else you might be next
#2 Oct 27, 2010
I Googled Eugene Kotelman, and this is all true. He has a long criminal record in several states, mostly for larceny and identity theft. In one instance, he sent a letter to his brother which contained names and SS numbers of fellow inmates for use when he got out. Authorities confiscated the letter and charged him for identity theft. If this guy is in Greeneville, everybody needs to know about him. He's bad news!
#3 Oct 27, 2010
Yeah I've seen that tool around town.
United States
#5 Oct 27, 2010
Wow! Like we don't have enough scum in greeneville that we need another one! We need to take back our town people from the drugs, thieves, and just all around POS! We used to have such a wonderful place to live and now look at it! Greeneville is going down hill fast! We need to put together some kind of system to where we could take back our town LEGALLY! I know the law had there hands full with this trash. So lets come up with something!
#6 Dec 12, 2010
Don't forget to catch his girlfriend Jamie Marie Lowery, cause if you don't she will continue on the tax scam legacy. It's really too bad that our government doesn't even know these hags are stealing from good people without their knowledge!!!
Gene was picked up in Carol County Kentucky 11/6/2010 but has been released already. Just remember all those trucks, harleys & RV's are paid for by stealing money!!!!
Since: Nov 10
#7 Dec 15, 2010
I just saw a Jamie Lowery in Tri-Cities busted last Thursday. I bet it is the same one.
#8 Dec 15, 2010
I have seen that truck down Shiloh Rd. a couple of times.
Fort Campbell, TN
#9 Dec 23, 2010
yea i whip the hell out them trucks bitches!!!! white trash
#10 Dec 23, 2010
Huh???? that makes absolutely no sense.
United States
#11 Mar 11, 2011
Well he's made it back to his birthplace in michigan. Had scammed about 30 people out of their 2010 returns.... Can't believe this guy is still out there and has not been stopped yet.... He must be one slick rick or he's related to some good ol boy who keeps his ass covered or is allowed to continue this criminal behavior by informing on others...either way its bullshit that he's living it up out there while michigan families have suffered so devastatingly with our economy.
#12 Apr 19, 2011
he has done this to many people and i am one of them ...he got over 8,000 from me i am going through irs right now just to get my stuff straighten out ...he was just here in florida flaunting his riches around and then got arrested but the rele already...what is that shi and it even say he is an out of state fugitive ...what is this world comming to?are we gonna let the hard criminals out on the streets and just lock up small time criminals????
#13 Jan 14, 2012
Warning to everyone that reads this, he's not only scamming everyone, and YES his "girlfriend" Jamie is in on it, but so is his other "Girlfriend" AMY THOMPSON! They've went through and scammed her entire family and all her friends. Amys such a treat she even left him after he beat her and broke 14 of her ribs, she stole all his shit, ie. Trucks, bike with the ? on it(shovelhead), his 5th Wheel, and TONS of other shit, came back to Michigan, gave everything to her friends and family as "sorry gifts" and was staying with a woman who she claimed was her best friend, slept with her fiance and when the fiance kicked her to the curb, she went back to Gene and is now blaming the entire family for stealing all his stuff and he's posting it all over his facebook and craigslist! EVERYONE AND ANYONE THAT SEES THEM STAY AWAY! To top matters, now rumored they both have HIV! So, as my poor friends have to do, go get tested if you've been in contact with these whores, not even sure if Jamie knows about the HIV! Most the last few years, Gene dumps Amy, goes to Jamie (Jamie and Amy are cousins and also both have children by the same man from before all this, seriously WHORES!) Gene drugs her up, gets her to steal a bunch of money, then he goes back to Amy with it. Almost feel bad for Jamie, but she knows exactly what she's doing too! Amy Thompson also goes by Amy Peters too, and I've heard has other alias's is as scantless! She's given her kids away countless times, not gotten then taken, GIVEN THEM AWAY! Whether it be her mother or other family, now they're both with their biological fathers, she signed over custody of her son when he was like 3, and I'm pretty sure he daughter is so lost in the system she doesn't have a legal guardian. Once she even stole her back from her biological father, only to go take her back to him again! She's scum, Gene is scum and they're BOTH wanted in at least 14 states, don't know how many counties. They're gypsies and have no address or at least didn't, they may have one know, they're so drugged up they steal, buy all the dope and toys they can, then when they're out of drugs, pawn the toys/vehicles/clothes etc. use it for more drugs while they go do MORE IRS scams. They go online and get EIN numbers when they can't find some poor innocent person to scam!! STAY AWAY FROM EUGENE CARL KOTELMAN AND AMY THOMPSON(PETERS)!!!
#15 Feb 23, 2012
Genes been in hickory,nc with jake mckelvey and lorie teniente living at 2525 highland ave ne. Theyre still robbing and taking advantage of ppl here in the same ways as. well as filing fraudulant taxes. Tey buy drugs,motorcycles n vehicles. Theyve got stolen property n kids living there while they lay up getting high.
#16 Sep 30, 2012
Gene Kotelman is now staying in port richey florida. with hope hall
#17 Nov 23, 2012
u know he's in pinellas county jail in florida looking at a long list of charges but he's getting $ out of hope hall right? she is helping support him in jail and loves him so much she send him out all drunk driving after he was bonded to drive?! just another trashy, low class woman to add to the list he will never marry or divorce his wife for. the man doesn't pay support on his children for goodness sakes the man has serious issues with truth or taking care of anything why do u think his wife left him because getting messed up means more to him then anything & if she did that then this only means every chick there after is just the one stupid enough to get messed u with him and willing to risk everything even her kids for his lifestyle and thinks nothing of herself because he's not going to divorce the mother of his kids because she's a great woman that showed him what no other scumbag trick can that she loves her kids more with him more than anything and in his eyes a mother's love means everything. those chicks are willing to loose their dignity with him and tell him they love him without commitment of real trash and are addicts like him that will do anything for their fix!
#18 Nov 23, 2012
well i cant feel sorry for no one with drug problems or stealing problems or mooch problems or criminal problems my ex stole all my savings, wrote bad checks on my account, stole my gold and diamond rings and diamond necklace, never paid a bill, made empty promises to try and get better with money if I would just give him time, stole from his job and i never snitched him out but when it came down to it i was too nice and believed him and that was from 6 yrs to 3 yrs ago and i wS still cordial to him cause im a nice person i didnt even do a police report just wanted to get along with the mooch loser and my advise to the woman above is to get out of relationship with user mooch loser because they do not change and ALOT more than the money stealing scamming could be going on people like the one i was with will go to extremes to hurt you when they are figured out for what they really are. you dont know how crazy people all drugged up act or what all theyre capable of if you have a loser thief in your life hide ya kids cause drugs fry ya brain and these type of guys dont have a pot to piss in so hold your head high and make a recovery for ur self. i cant stand a worthless man theres a lot more this is just a summary of how low life people do and use and abuse and hurt there own kids when they get all F' up on drugs they cant afford like meth so on this Thanksgiving im thankful to not have a rotten mouthed sexual predator thieving lying stealing drug addict that i have to look at Oh and the leftovers are in the microwave - the fifth one i ve had in five years who knew they cooked that stuff in their
#19 Nov 23, 2012
do anybody know what drugs blow up a microwave thats what i asking
#20 Nov 23, 2012
#21 Mar 14, 2013
Looking up someone's name on Google and came across this.... I don't think anyone should write anything negative about Hope Halllll considering know one knows anything about her, and if they do know her by some chance then they would know she is not anything other than her own person, not one that needs to follow what everyone else is doing, or the one that let's someone buy her a drink she buys her own because she don't care to be impressed with what the wallet provides.... She doesn't do cracked,pills, or even smoke weed so catching a fix is not her case... Her kids are her world and considering she has taken custody of a child that has know blood relation to her and has every kid on the block at her house everyday all week would tell you she would never give someone the time or day that tries to take her away from her children... She also believes she can still change the world so why slander her name let her change the world on her own or until she figures it out her self that people don't change and people shouldn't be trusted that have a bad rap....
#22 Dec 26, 2013
Gene kotelman is back out in florida got release again after serving less than 2 years he probably narked on some poor innocent person or family. he myst be stopped one way or another. lets get him and end it ourselves bc obviously the athorities aint doin shit
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LAKELAND, Fla. — Publix Super Markets here and Wal-Mart Stores, Bentonville, Ark., were among the first major food retailers to unveil aid programs Wednesday in the wake of the massive earthquake that hit Haiti this week. Publix said customers may donate by adding to their grocery totals when checking out. Collected money will be channeled through the American Red Cross and designated specifically for the Haiti Relief & Development Fund. "This devastating disaster to Haiti hits close ...
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