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Paradise Postponed Paperback – Jun 1989
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From Publishers Weekly
Why does Simeon Simcox, "left-wing cleric" of an English village, leave the Simcox brewery millions to the morally loathsome Leslie "The Toad" Titmuss, city developer and Conservative cabinet minister? Simeon's sonsFred, the jazz-drumming doctor, and writer Henry, once "Britain's brightest and angriest"conduct separate sleuthing inquiries into Simeon's life and will. Was the low-born Titmuss, who has bought and sold his upper-crust associates and climbed to power on their crippled backs, really Simeon's offspring? Barrister, playwright, scriptwriter, novelist Mortimer (Rumpole of the Bailey brings his legal expertise and somber humor to this competently cobbled, though dogged, plot that takes in the upheavals of British society from the '40s to the '70s. Where the gentry once rode to hounds, the constabulary now rides against women camping on the heath to protest the Cruise missile. Despite some funny scenes of sitcom buffoonery, readers are apt to feel indifferent to the squads of characters that Mortimer parades forth, who are largely representatives of social forces, with little human blood in them. 25,000 first printing; BOMC alternate.
Copyright 1986 Reed Business Information, Inc. --This text refers to an out of print or unavailable edition of this title.
From Library Journal
Mortimer, known for his Rumpole series, here offers the life of Rector Simeon Simcos in the small English village of Rapstone Fanner. LJ's reviewer found Mortimer's writing "witty and the wordplay entertaining" but thought the plot a little "flimsy" (LJ 4/1/86).
Copyright 1997 Reed Business Information, Inc. --This text refers to an out of print or unavailable edition of this title.
Customer Reviews
Top Customer Reviews
What surprises me is that the TV adaptation of Paradise Postponed has never been released on video, at least in the U.S. There'd be a large market for it.
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What surprises me is that the TV adaptation of Paradise Postponed has never been released on video, at least in the U.S. There'd be a large market for it.
I found the plot-line in this novel very good indeed. The main mystery is cleared up in a very unexpected way, all hints and suggestions really lead somewhere, and while I suppose I would have to call it contrived, it is clever enough to be convincing in its own way. It is clever in the sense of being complex, but also in the way that Mortimer keeps switching the time-focus between different eras. He takes us from the start of Attlee's Labour government in 1945 all the way to the reign of Margaret in the 80's. The story of the will would not by itself have required a 40-year elapse. What requires that is the introduction of Leslie Titmuss, depicted starting with his modest boyhood and ending, in this book, with his fictional presence in Thatcher's cabinet. It needs no great legal genius to perceive that he is going to be good for a few more books, and so, of course, it has turned out.
So there is a political angle too, and if you know your author you will have expected that. He was one kind of leftist, and a kind that I greatly like. He had a privileged background, and he was `anti' just by nature. He was a rationalist and he was a libertarian. He found the toffs with origins similar to his own to be absurd and repulsive, but he was no Orwell, no wholesale convert to some other side. The colonel's lady and Judy O'Grady are sisters under the skin, after all. It's a human skin, and it's humanity in general that is prone to being absurd.
The characterisation is largely drawn from a political slant, therefore. Mortimer is not pushing any party-political programme all the same. Just describe some Young Conservatives, I suppose, and further comment would be superfluous. However the reverend himself, whose strange-seeming will forms the core of the narrative, is depicted as a self-caricaturing lefty, while Mortimer is conspicuously restrained in anything that might be construed as hostility to Titmuss, whose views must have been in many respects antithetical to his own. Malcolm Muggeridge, in his latter days as a born-again Christian and reactionary, had an excellent description for a whole tranche of C of E clergymen of this period, with their `feeble-minded confusion of the Christian faith with better housing, shorter hours of work, the United Nations and opposition to apartheid.' These are the polar examples. The others - I found them brilliantly drawn and developed altogether.
However in Mortimer there is always a good deal of social commentary, with minor characters put there for the overall picture and not for themselves. In many ways this is the best thing in the book, and it comes mainly at the beginning. You can't tell me that the schoolmates of Fred and Henry at their fictitious public school in East Anglia are not drawn from life. Mortimer attended Harrow School (as did Churchill), and they used to tell them there that the wind from the Urals hit Harrow-on-the-Hill without encountering any intermediate obstruction. Mortimer borrows this piece of lore for his school here in the book, so I infer that the incidental personae who come and go in the first chapter or two are real, with only the names changed to protect the questionably innocent. In particular there was apparently one boy who had a premature 5-o'clock shadow and was a great masturbator. He features in just a sentence or two, is never heard of again, and one is left wondering whether his onanistic eminence was a matter of a record level of activity, or whether he needed both hands simultaneously for the job, or exactly what it was. Somebody still alive might still remember.
The style of writing is of course delightful, but I caught Mortimer recycling a sentence that I had heard him use on television at least once, to the effect that there is no pleasure worth denying oneself for the sake of a few years in a sunset home in Weston-super-Mare. Poor old Weston-super-Mare. It is 60 years since I was there last, but having been warned off in this way I am electing to manage my later years by attending a gymnasium and eating and drinking less. Advancing age makes the latter pleasures less attractive anyway, to me at least. The book also features an elderly doctor who is largely there for the purpose of saying witty things, rather like Lord whatsisname in A Picture of Dorian Gray. This is entirely welcome. The doctor belongs properly in the narrative, and I would only utter a mild remonstrance for the pageful of his bons mots that is only there because Mortimer could not fit them into the story.
Behind the upper-middle-class English flippancy there is also a darker side to all this, and mentioning the doctor above reminds me of that. To me, it is all a potent brew, and I recommend the book thoroughly. Sir John Mortimer left our society only recently, but not before he had used at least one of his books to sound a coded but powerful warning of the threats to liberty that were being enacted by the over-plausible and endlessly self-justifying Tony Blair. The libertarian mentality runs through Mortimer's output, the threats to liberty depend on the eternal vigilance that is trumpeted so often by some of the people who threaten liberty most and are trying to hijack the vocabulary to their own political cause. Mortimer is good for our mental health.
Oh yes, there's also the mystery of the will of Simeon Simcox, late pacifist, socialist vicar which bequeaths all to weaselly Conservative Cabinet MP Leslie Titmuss. The narrative is a bit rum on this point in that the said Simeon Simcox is actually alive throughout most of the novel as the story backtracks through time or rather hopscotches around it - more often than not from paragraph to paragraph, with no clear demarcation given - which takes a bit of getting used to, whilst also keeping the reader on his/her toes.
A very lively, satisfactory read indeed, except that one is still left pondering why exactly the Bertrand Russell reading, seemingly atheistical Simcox became a vicar in the first place. Oh well, it's just as well to have something on which to chew after one turns the last pages.
Mortimer is particularly deft in employing literary quotations to summarise entire sections of the book. The Kierkegaard quote summarising Part Three might well be employed to give the prospective reader an idea of the entire book's underlying theme and motif:
"Life must be lived forwards, but it can only be understood backwards."
The cast of characters is terrific (my favorite is the snobbish Lady Fanner, who cannot stand her clumsy and unhappy daughter Charlotte), and in the best of the English tradition of the comic novel of manners (exemplified by Austen, Oliphant, Trollope, Meredith, Forster, Waugh, and Angus Wilson), the characters are allowed multiple sides to them--even the odious Titmuss himself. There are great setpieces, several of which involve the gentle attempts of Simeon Simcox to please a child that go disastrously awry and which made me laugh out loud. I worried near the end of the novel that Mortimer's attempts to make this novel too much of an allegory for the inheritance of England would make it too programmatic by the end, but though perhaps his points about the Thatcher era are hammered home a little too insistently at times the whole thing comes off as a huge success.
Although there's no murder to be solved the story presents a mystery which troubles the minds of the rector's two sons--almost to the point of paranoia. They both want the truth at any cost: one to discredit their father's reputation; the other to restore it. Simeon's secret must be known to Someone, but no one will take the frustrated and feuding sons out of their misery--least of all their mother! So why did Simeon leave a large inheritance (in the form of shares in Simcox Ales) to an unpopular cabinet minister named Leslie Titmuss? Elder son, Henry the playwright, is outraged that their father did not provide for his wife and children; thus he's desperate to prove that the rector was mentally unbalanced. He will stop at nothing to reclaim the inheritance which he feels is due his family. Meanwhile the younger son, Fred the doctor, seeks an alternative reason for his father's irrational generosity; he will do anything--invade any sanctum--to prove to the world that his father was Not insane.
Mortimer employs a huge cast of characters--some of whom pop up in different eras--to the surprise of the Simcox family. Taking readers on a circuitous journey through various, non-sequential decades the author presents both an absurd, yet amusing tapestry of social and political change/progress. He also aims the spotlight on British prolonged class consciousness and the hardship of people In Service--an institution only found in Britain. Family dynamics are depicted objectively, with all their human foibles and psychological cruelty
In this literary patchwork quilt of the latter half of the 20th century Mortimer discusses the following topics/institutions: strikes and demonstrations, theft and blackmail, poaching, private school hazing, and even the evolution of popular music. Readers are also reminded of the dangers of false pride and of young people's engaging in unprotected sex, as well as the comically bizarre world of senility, moral guilt and intergenerational errors. Quite a list--which should provide something of interest to every reader--in between the gradual revelation of past crimes and unspoken guilt. Simeon Simcox: Saint or Sinner?
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CHICAGO — Living in a "food desert" — such as a neighborhood on this city's South Side — can have a negative impact on one's health, according to a study of five local areas with no full-service grocery stores that was conducted by researcher Mari Gallagher. As reported by the Chicago Sun-Times, adding a supermarket to a neighborhood could, collectively, mean a gain of up to 15 years of life for those suffering from diabetes; 13 years for those with liver disease; 58 years for people with ...
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Mark Burris obit. - 16 September 1899 - 20 July 1919 - Tragic accident, 19 year old Mark was killed when his horse jumped off the Roaring River Bridge with Mark while he was on the way to a party at the childhood home of my mother, nearby farm of his 1st cousins. The horse stood over his body in the shallow river all night, causing some boys to find the body (next morning) when they recognized his horse and went to see about it.


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Destiny's Child member Kelly Rowland and Michelle Williams(the other Michelle Williams)| have been doting of Beyonce & Jay-Z's little wondergirl. The former bandmates of Beyonce have gone to see their friend and say that the couple have taken very well to their new roles of … [Read more...]
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Partial closure on Alton expected
A stretch of Alton Parkway is expected to close for about two months this summer, according to Lake Forest public works officials.
The road will be closed temporarily from Commercentre Drive to Rancho Parkway South as part of ongoing construction at the Baker Ranch residential development.
Construction workers will be moving graded dirt from the south side of the road to the north side.
While the dates the road will be closed are not yet set, city staffers said electronic message signs will be posted.
For information, call the Public Works Department at 949-461-3480.
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The Sussex is a conveniently located, traditional British pub in Brighton city centre, ideally placed for a great night out. Plus we have negotiated a special 10% discount on drinks all night - enjoy!
Was great meeting you all yesterday :) Super soirée !
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It was great to see everyone, had a great time . Thanks to Susan and Glenn
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Hi all! I may only be able to come for an hour but would be great to meet you all!
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Hi all. Sorry but I won't be able to make it tonight. Hope you all have a great time. Kennedy.
0 · April 26, 2014
Hi looking forward to another fantastic time :)
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text:
anti-tachycardia pacing
congenital heart defect
computed tomography
cardioversion threshold
defibrillation threshold
implantable cardioverter-defibrillator
long axis
magnetic resonance imaging/image
right ventricle
subcutaneous implantable cardioverter-defibrillator
short axis
virtual electrode polarization
ventricular fibrillation
- V m
transmembrane potential
ventricular tachycardia
- Φe
extracellular potential
Placement of implantable cardioverter-defibrillators in paediatric and congenital heart defect patients: a pipeline for model generation and simulation prediction of optimal configurations
N. A. Trayanova: Johns Hopkins University, 3400 N Charles St., 216 Hackerman Hall, Baltimore, MD 21218, USA. Email: email@example.com
Key points
- • Implantable cardioverter-defibrillators (ICDs) with transvenous leads often cannot be implanted in a standard manner in paediatric and congenital heart defect (CHD) patients. Currently, there is no reliable approach to predict the optimal ICD placement in these patients.
- • A pipeline for constructing personalized, electrophysiological heart–torso models from clinical magnetic resonance imaging scans was developed and applied to a paediatric CHD patient.
- • Optimal ICD placement was determined using patient-specific simulations of the defibrillation process. In a patient with tricuspid valve atresia, two configurations with epicardial leads were found to have the lowest defibrillation threshold.
- • We demonstrated that determining extracellular potential (Φe) gradients during the shock – without actually simulating defibrillation – was not sufficient to predict defibrillation success or failure.
- • Using the proposed methodology, the optimal ICD placement in paediatric/CHD patients can be predicted computationally, which could reduce defibrillation energy if the pipeline is used as part of ICD implantation planning.
Abstract There is currently no reliable way of predicting the optimal implantable cardioverter-defibrillator (ICD) placement in paediatric and congenital heart defect (CHD) patients. This study aimed to: (1) develop a new image processing pipeline for constructing patient-specific heart–torso models from clinical magnetic resonance images (MRIs); (2) use the pipeline to determine the optimal ICD configuration in a paediatric tricuspid valve atresia patient; (3) establish whether the widely used criterion of shock-induced extracellular potential (Φe) gradients ≥5 V cm−1 in ≥95% of ventricular volume predicts defibrillation success. A biophysically detailed heart–torso model was generated from patient MRIs. Because transvenous access was impossible, three subcutaneous and three epicardial lead placement sites were identified along with five ICD scan locations. Ventricular fibrillation was induced, and defibrillation shocks were applied from 11 ICD configurations to determine defibrillation thresholds (DFTs). Two configurations with epicardial leads resulted in the lowest DFTs overall and were thus considered optimal. Three configurations shared the lowest DFT among subcutaneous lead ICDs. The Φe gradient criterion was an inadequate predictor of defibrillation success, as defibrillation failed in numerous instances even when 100% of the myocardium experienced such gradients. In conclusion, we have developed a new image processing pipeline and applied it to a CHD patient to construct the first active heart–torso model from clinical MRIs.
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Defibrillation by strong electric shock is the only known procedure that reliably terminates ventricular fibrillation (VF). Implantable cardioverter-defibrillators (ICDs) have recently been implanted with increasing frequency in the paediatric population and in patients with congenital heart defects (CHDs) (Berul et al. 2008). In these patients, it is often not indicated or even impossible to implant a transvenous lead ICD because of the patient's small heart size and congenitally altered anatomy, so non-standard ICD configurations have to be used (Silka et al. 1993; Stephenson et al. 2006). Such ICD configurations commonly involve individualized epicardial or subcutaneous lead placement (Berul et al. 2001; Gradaus et al. 2001; Thogersen et al. 2001; Stephenson et al. 2006). However, there is currently no reliable, personalized way of predicting which ICD configuration would have the lowest defibrillation and cardioverstion thresholds (DFT and CVT) in a patient. In this study, we consider the configuration that exhibited the lowest DFT and CVT among tested ICD placement options as the optimal configuration. A low DFT is desirable because strong electric shocks damage cardiac myocytes (Walcott et al. 2003), increase mortality (Larsen et al. 2011), and can cause pain and psychological trauma (Maisel, 2006). Thus, it is important to be able to predict the optimal ICD configuration for a specific patient, especially in the case of a paediatric and/or CHD patient if a transvenous lead ICD configuration cannot be used.
A previous study has endeavoured to determine computationally the DFTs associated with different ICD configurations in an attempt to predict the optimal ICD configurations in paediatric and CHD patients (Jolley et al. 2008). While patient-specific torso models have been developed for this purpose from high-resolution computed tomography (CT) scans (the latter being a concern for radiation overexposure; Brenner & Hall, 2007), the models did not simulate the process of defibrillation, but rather used the criterion of static extracellular potential (Φe) gradient values above 5 V cm−1 in more than 95% of the volume of the passive ventricles during the shock as a surrogate for the DFT (Jolley et al. 2008). This criterion is based on the critical mass hypothesis, which postulates that a defibrillation shock is successful if it produces a strong Φe gradient over a large amount of ventricular tissue mass (Zipes et al. 1975; Zhou et al. 1993). This surrogate DFT criterion has been used in a number of computational defibrillation studies (Eason et al. 1998; de Jongh et al. 1999; Hunt & de Jongh Curry, 2004, 2006; Russomanno et al. 2008; Jolley et al. 2010). While Φe gradients are a determinant of post-shock activity in the heart, other mechanisms are at play as well (Knisley et al. 1999; Trayanova, 2001): not only Φe gradients but also cardiac tissue structure is responsible for virtual electrode polarizations (VEPs; depolarizing and hyperpolarizing changes in membrane potential in response to an electric field) that can generate or abolish wavefronts (Sobie et al. 1997; Efimov et al. 1998; Trayanova et al. 1998; Efimov & Ripplinger, 2006). In addition, not only what happens during the shock but events after the shock determine defibrillation outcome, as in the case of graded responses (Trayanova et al. 2003; Bourn et al. 2006) or tunnel propagation (Ashihara et al. 2008; Constantino et al. 2010). Thus, it remains questionable if any measure that accounts only for static Φe gradients could be a valid surrogate measure of defibrillation outcome, and whether such a criterion could be applied in determining the optimal ICD configurations in paediatric and CHD patients.
The aims of this study were: (1) to develop a new image processing pipeline for the construction of patient-specific heart–torso models from low-resolution clinical magnetic resonance imaging (MRI) data; (2) using this pipeline, to develop the first electrophysiological active heart–torso defibrillation model of a paediatric CHD patient, and to determine the optimal ICD configuration in that patient based on simulations of defibrillation outcome and DFT; and (3) to investigate if a measure of Φe gradients during the shock in a given volume of the ventricles can be used to predict defibrillation outcome and the DFT.
A brief presentation of the methods is given here; additional detail is provided in the Supplemental methods section.
Ethical approval
This study analysed de-identified, existing human MRI scans and was thus not considered human subject research according to Johns Hopkins Medicine Institutional Review Board guidelines.
Data acquisition
A clinical MRI (1.5 T) dataset had previously been acquired from a 14-year-old male paediatric patient with tricuspid valve atresia. The patient had a previous modified Blalock–Taussig shunt followed by bilateral bidirectional Glenn shunts. Finally, the patient had a Fontan procedure using a 12 mm extracardiac conduit. This patient was chosen for the anatomical complexity of his congenital condition and for MRI data quality; the patient did not receive an implanted defibrillator. The dataset had been de-identified before the study. Because of the tricuspid valve atresia, the right ventricle (RV) was hypoplastic and could not be delineated from the clinical low-resolution MRIs. This dataset included axial torso scans, and short-axis (SA) and long-axis (LA) cardiac cine scans. The axial image (27 slices, 384 × 300 pixels each) had a resolution of 1 × 1 × 6 mm3, and the SA cine scans (11 slices, 144 × 192 pixels each) had a resolution of 2 × 2 × 10 mm3 (Fig. 1A).
Image processing pipeline for heart–torso model construction from clinical MRI data
A novel pipeline was developed for constructing smooth and locally refined active heart–torso models with ventricular fibre architecture from low-resolution clinical MRI scans, using advanced image processing techniques. The heart–torso model of the paediatric patient with tricuspid valve atresia was used as the proof-of-principle example. The methodology described here can be applied to any clinical MRI dataset of similar (or higher) resolution.
In each slice in the axial torso image (27 slices in this dataset), tissue regions (six regions here: lungs, fat, bones, blood, muscles, torso outline) were manually labelled, creating several sets of binary image slices, each set corresponding to one tissue type. Each set was then interpolated into 1 mm isotropic resolution using the variational implicit functions method (Turk & O'Brien, 1999), and the interpolated data merged to form one image. The outer three pixels of the torso outline were then labelled as skin, and the remainder of the torso outline tissue type was labelled as conductive medium. By labelling the above tissue types, a segmented three-dimensional (3D) image of the torso labelled with tissue types (seven tissue types here, not yet including the heart) was generated. This labelled 3D image had a significantly smaller voxel size than the acquired clinical MRI, as interpolation estimated a large amount of missing data.
From the low-resolution SA cine image of the patient heart, a binary image of the ventricular geometry in diastole was built at a 1 mm isotropic voxel size (only the left ventricle in this patient as the RV could not be delineated). In this process, the breathing motion errors in the SA data were first eliminated based on horizontal and vertical LA scans, as described elsewhere (Elen et al. 2010). Epi- and endocardial contours were manually drawn on the motion-corrected SA slices, with papillary muscles included as part of the ventricular wall. The contours were interpolated to create a 1 mm isotropic 3D image of the ventricular geometry with separate labels for ventricular tissue and blood, as reported previously (Vadakkumpadan et al. 2012). This image was then merged with the segmented image of the torso by means of coordinate transformations calculated from acquired image header data, to create the final image of the torso and heart, labelled with different tissue types (eight tissue types here).
An unstructured mesh was automatically generated from the final image using the methodology developed by Prassl et al. (2009). This methodology employs an efficient octree-based algorithm to produce boundary-fitted, locally refined, smooth conformal meshes directly from segmented images. The ventricular region of the mesh was locally refined, and the rest of the torso coarsened, to reduce the mesh size without compromising important geometric detail. Mean edge length, number of nodes and number of elements of the tricuspid valve atresia heart–torso mesh in this study are given in Fig. 1B. Fibre and sheet orientations were assigned to the ventricular elements using a recently developed and validated rule-based technique (Bayer et al. 2012). Figure 1C presents a streamlined visualization of the fibre orientations. Additional details about the model construction pipeline can be found in the Supplemental methods section.
Model formulation and parameters
The finite element mesh constructed with the above pipeline was parameterized as described below to construct the first human heart–torso defibrillation model with an active, multi-scale model of the heart. The mathematical description of current flow in cardiac tissue was based on the bidomain and monodomain representations. The bidomain formulation was used when shocks were applied, and for computation of the electrocardiogram (ECG), whereas the computationally less demanding monodomain formulation was used to simulate propagation in the absence of externally applied electric fields. The bidomain and monodomain equations were solved with the Cardiac Arrhythmia Research Package (CARP) (Vigmond et al. 2002, 2003).
Ionic properties of cardiac myocytes were modelled with the ten Tusscher model of the human ventricular myocyte (ten Tusscher & Panfilov, 2006). Realistic apico-basal (Szentadrassy et al. 2005; Okada et al. 2011) and transmural (Glukhov et al. 2010; Moreno et al. 2011) electrophysiological heterogeneities were incorporated into the model, and longitudinal, transverse and sheet-normal conductivities (Poelzing et al. 2004; Caldwell et al. 2009) were chosen to achieve realistic propagation patterns as described in the Supplemental methods section. The conductivities of the non-ventricular tissue types (bones, lungs, skin, blood, muscles, fat, remaining conductive medium) were the same as in Jolley et al. (2008), with conductivity values of the skin assumed equal to that of the torso conductive medium (Jolley et al. 2008).
ICD placement
Due to the tricuspid valve atresia, there was no transvenous access to the RV and thus placement of a transvenous lead ICD was not possible. Hence, a non-standard ICD configuration had to be used. Several ICD configurations were tested using various locations of the ICD can and of the ICD lead (or leads in the case of configurations with multiple leads). Five realistic placement options for the ICD can were identified. Two of these ICD can locations were on the upper chest, two on the lower chest, and one was a sub-axillary location (Fig. 2). The dimensions of the ICD can were 6 × 5 × 1.5 cm3, roughly the size of most ICD cans used today. Next, six locations for the placement of the ICD lead were identified, three on the epicardium and three subcutaneous (Fig. 2). The choice of lead placement options was based on Stephenson et al. (2006), and enabled the exploration of both epicardial and subcutaneous lead locations and multiple electric field vectors. ICD lead dimensions were 5 × 0.2 × 0.2 cm3, roughly the size of the RV coil of a typical transvenous ICD lead, as this type of lead is commonly used 'off-label' for non-transvenous lead placement in the paediatric and CHD populations (Stephenson et al. 2006; Radbill et al. 2012). From the chosen ICD can and lead locations, 11 ICD configurations were assembled so that the shock vector would be across the ventricles for each configuration, and so that configurations with epicardial leads and with single and multiple subcutaneous leads could be tested. Thus, each ICD configuration consisted of one ICD can and between one and three ICD leads. Three of the 11 ICD configurations had epicardial leads, five had single subcutaneous leads and three had multiple subcutaneous leads (Fig. 2).
Study protocol
The ECGs were computed as described in the Supplemental methods section. As the heart model lacked a representation of the atria, the P wave was absent from the simulated ECGs. Sinus rhythm was simulated using a cable-based representation of the Purkinje system, where Purkinje activation in response to His bundle stimulation was simulated and junctional activation times were used as pacing timing offsets for sinus rhythm simulation (see Supplemental Fig. S2). Additional detail on the Purkinje cable formulation is given in the Supplemental methods section.
Defibrillation shocks were delivered to the constructed human heart–torso model, which incorporated the ionic processes in ventricular myocytes. VT and VF were induced as described in the Supplemental methods. To ensure shock delivery during different 'phases' of VF and VT, three different instants (or phases) during VF and three different instants during VT – i.e. different pre-shock transmembrane potential (Vm) distributions in the ventricles during VT and VF – were chosen to apply electric shocks to. Exponentially truncated, biphasic defibrillation or cardioversion shocks of 7 ms duration (3.5 ms duration and 50% tilt in each phase, positive polarity in first phase) as used in our previous study (Rantner et al. 2012), and based on experimental findings about effective defibrillation waveforms (Efimov et al. 1998), were applied from the ICD leads of the 11 ICD configurations, with the ICD can used as ground. A DFT grid – a 2D grid representing defibrillation outcomes for the 11 ICD configurations – for the three VF instants, and for a range of shock strengths, was assembled for shocks applied to the fibrillating heart, and a CVT grid – an analogue to the DFT grid, but representing the outcomes of VT cardioversion shocks – was constructed for shocks applied during VT. The DFT and CVT were defined as the lowest energy shocks that terminated the arrhythmia for all VF and VT phases, respectively. Arrhythmia was considered terminated if no propagation was present 1 s after shock onset. Further details on how the DFT and CVT grids were constructed are provided in the Supplemental methods.
The rationale for constructing both a DFT and a CVT grid to be used in choosing the optimal ICD configuration in the paediatric CHD patient was as follows. To prevent sudden cardiac death, an ICD must be capable of terminating VF. An ICD also needs to be able to terminate VT, as cardioversion by electric shock might have to be applied if anti-tachycardia pacing (ATP) fails (Kalra et al. 2012) or if ATP is not possible due to the absence of a pace–sense lead in certain ICD configurations. The occurrence of VT in CHD patients, specifically in patients with repaired tetralogy of Fallot, is well documented (Walsh, 2002; Nakazawa et al. 2004). ICD configurations that led to both low DFT and low CVT were considered favourable here.
Heart–torso model and ECG
The tricuspid valve atresia heart–torso model is presented in Fig. 2; different tissue regions throughout the torso are clearly visible (shown are ventricle, bones, lungs and skin; not shown are blood, muscles, fat and remaining conductive medium). Select clinically recorded ECG traces from the tricuspid valve atresia patient as well as simulated ECGs are shown in Fig. 3. The simulated ECG traces match the clinical recordings very well, especially for the limb leads and augmented limb leads, showing that the heart–torso model is an appropriate representation of the patient's overall electrophysiology. Additional simulation results regarding the ECGs are provided in the Supplemental results section.
Defibrillation and cardioversion thresholds
Figure 4 shows Vm maps of the three VF and three VT pre-shock phases, along with 2 s excerpts of limb lead ECG recordings during VF and VT. Figure 5 presents the DFT grid for the 11 ICD configurations. DFTs were lowest for ICD configurations with an epicardial lead. Even the lowest DFT among ICD configurations with subcutaneous leads was four times the highest DFT for configurations with an epicardial lead. There was a four-fold difference between the highest and lowest DFTs among ICD configurations with a single subcutaneous lead. There was an eight-fold difference between the highest and lowest DFTs among ICD configurations with multiple subcutaneous. The highest DFT among all 11 ICD configurations was 64 times the lowest DFT.
Figure 6 shows the CVT grid. Not only DFTs, but also CVTs were lowest for ICD configurations with epicardial leads. The lowest CVT for ICD configurations with subcutaneous leads was twice the highest CVT among any configuration with an epicardial lead. There was a four-fold difference between the highest and lowest CVTs among single subcutaneous lead ICD configurations. Likewise, the highest CVT of an ICD configuration with multiple subcutaneous leads was four times the lowest CVT among multiple subcutaneous lead configurations. Of all 11 ICD configurations, there was a 16-fold difference between the highest and lowest CVTs.
The ICD configuration with a left epicardial lead and a right chest can (LEpiL2RCC in Figs 5 and 6) as well as the configuration with a posterior epicardial lead and a left chest can (PEpiL2LCC in Figs 5 and 6) had both the lowest DFT and CVT overall. Among the configurations with a single subcutaneous lead, a left para-sternal lead and sub-axillary can (LPSL2SAC in Figs 5 and 6) resulted in the lowest DFT and CVT. The same DFT and CVT was shared by two configurations with multiple subcutaneous leads: the ICD configuration with a left subcutaneous lead, a posterior subcutaneous lead, a left para-sternal lead and a sub-clavicular can (LSqLPSqLLPSL2SCC in Figs 5 and 6); and the configuration with a posterior subcutaneous lead, a left para-sternal lead and a sub-clavicular can (PSqLLPSL2SCC in Figs 5 and 6).
Extracellular potentials and the criterion for successful defibrillation
To determine whether a criterion using only Φe gradients can be used to predict defibrillation outcome and the DFT, as stated in the Introduction, we calculated Φe gradients during all defibrillation and cardioversion shocks. Figure 7 presents maps of Φe gradient distributions 1 ms after the onset of 80 J shocks. Data on the Φe gradients from Fig. 7 are also presented in Supplemental Table S3. Supplemental Figure S7 presents a plot of the Φe gradients from Fig. 7 against the corresponding DFTs and CVTs. The Φe gradients were largest during shocks from ICD configurations with epicardial leads, having a mean Φe gradient of 25.82 ± 6.21 V cm−1 in the ventricular volume. ICD configurations with multiple subcutaneous leads had a mean ventricular Φe gradient of 7.96 ± 0.26 V cm−1. Single subcutaneous lead ICD configurations had a mean Φe gradient of 7.80 ± 2.50 V cm−1 in the ventricle.
While the Φe gradient distributions of two configurations with multiple subcutaneous leads (LSqLPSqLLPSL2SCC and PSqLLPSL2SCC in Fig. 7) looked virtually identical, one configuration had an eight times higher DFT (Fig. 5) and a four times higher CVT (Fig. 6) than the other. This indicated that Φe gradients alone were not determinants of defibrillation outcome.
To determine if a criterion used in many simulation studies – namely declaring defibrillation success if ≥95 % of ventricular tissue experienced Φe gradients ≥5 V cm−1 during the shock – is a valid surrogate measure for defibrillation success and the DFT, the amount of ventricular tissue experiencing Φe gradients ≥5 V cm−1 was determined for all defibrillation and cardioversion shocks. The blue numbers in Figs 5 and 6 show the percentage of ventricular volume that experienced Φe gradients ≥5 V cm−1 during the shocks (for reference, the threshold value of 5 V cm−1 is also marked in the colour bar of Fig. 7 with the magenta line). For a given shock energy, this percentage was generally higher for ICD configurations with epicardial leads than for subcutaneous leads. All DFT shocks resulted in Φe gradients ≥5 V cm−1 in 100% of ventricular tissue, and CVT shocks caused Φe gradients ≥5 V cm−1 in at least 99.5% of the ventricle. On the other hand, even a large number of shocks below the DFT and CVT resulted in Φe gradients ≥5 V cm−1 in 100% of ventricular tissue. For certain ICD configurations, shocks of only 6.25% of DFT strength experienced such Φe gradients in the entire ventricle, demonstrating that Φe gradients ≥5 V cm−1 in a certain fraction of the heart – or even in the entire heart – were not sufficient to predict defibrillation success or failure.
In accordance with our aims, as stated in the Introduction, we developed a new image processing pipeline for building patient-specific heart–torso models from low-resolution, clinical MRIs. Using this pipeline, we constructed the first electrophysiological, active, multi-scale heart–torso model of a paediatric patient with CHD. We then conducted simulations to determine the optimal ICD configuration for this patient. Two configurations with epicardial leads exhibited the lowest DFTs and CVTs here and were thus the optimal choices. Finally, we endeavoured to establish whether the widely used criterion of shock-induced Φe gradients ≥5 V cm−1 in ≥95 % of ventricular volume predicts defibrillation success. Our study demonstrated that this criterion could not reliably predict defibrillation outcome; the predictions based on that criterion were very different from the predictions made with the detailed multiscale simulations used here.
While previous studies have also attempted to predict DFTs in computational torso models, most recently by Jolley et al. (2008) in CT-based models of paediatric and CHD patients, the current study provides three major advancements over these efforts: (1) our model was developed from readily available, clinical MRI scans instead of high-resolution CT scans; (2) we incorporated fibre architecture instead of using an isotropic ventricular model; and (3) our study used an electrophysiological, active ventricular model to simulate actual VF and defibrillation, as opposed to modelling only the applied electric field without the myocardial response to the field. To translate any computer model-based prediction of optimal ICD placement to the clinic, it would be desirable to use MRI instead of CT scans for model construction, circumventing concerns about radiation exposure; our model presents a major step in this direction. While the model presented here is, to the best of our knowledge, the first MRI-derived heart–torso model of a CHD patient reconstructed from MRI scans, attempts to construct heart–torso models from MRI datasets have been made in the past, but only for patients with structurally normal hearts. Such models have been employed in the study of defibrillation (Eason et al. 1998; de Jongh et al. 1999; Russomanno et al. 2008) as well as for other uses (Tilg et al. 2002; Berger et al. 2006; Vanheusden et al. 2012). None of these models, however, included an active ventricular model, and they were of much coarser resolution than our model – especially in the ventricular. The resolution of the finite element mesh of our model was fine enough to simulate electric propagation in detail, yet the overall number of nodes and elements was small enough for the model to be computationally tractable; in addition to ventricular tissue, the model also included representations of bones, lungs, blood, muscles, fat, skin and conductive medium with realistic conductivities in order to be able to accurately model the shock-induced electric fields in the torso. Our model overcomes the limitations of previous heart–torso models such as the use of a canine heart model instead of human (Eason et al. 1998), not accounting for fibre architecture and tissue anisotropy (de Jongh et al. 1999; Tilg et al. 2002; Berger et al. 2006; Russomanno et al. 2008; Vanheusden et al. 2012), or only estimating the myocardial surfaces based on a certain distance from ventricular blood masses, but not detecting and modelling the myocardial volume itself (Tilg et al. 2002; Berger et al. 2006). The model construction pipeline proposed here uses advanced image processing and meshing techniques to combine axial MRI and cine MRI scans to build a detailed heart–torso model with a high resolution and with smooth surfaces in the ventricles, and assigns fibre orientation based on chamber geometry. The pipeline can specifically be applied to construct models of paediatric and CHD patients.
Previous numerical defibrillation studies using torso models did not determine the actual DFT, but due to the lack of an active ventricular model, relied on a 'pseudo-DFT' criterion (lowest shock strength to result in Φe gradients ≥5 V cm−1 in ≥95 % of the passive ventricles) instead (Eason et al. 1998; de Jongh et al. 1999; Jolley et al. 2008, 2010; Russomanno et al. 2008). The current study used an active ventricular model, and enabled us not only to calculate Φe gradients but also to simulate the defibrillation process and determine the actual DFT for the tested ICD configurations. Simulating defibrillation is computationally much more demanding than only applying an electric field and computing Φe gradients in the passive heart model, so it would be beneficial if a pseudo-DFT criterion could be used instead of the actual DFT in attempts to optimize ICD placement. Our study demonstrated, however, that the pseudo-DFT criterion used in previous studies was not an appropriate predictor of the success or failure of defibrillation, as determined here: while all shocks at and above DFT fulfilled the pseudo-DFT criterion, many shocks below the DFT fulfilled that criterion as well. For some of the ICD configurations tested, there were Φe gradients ≥5 V cm−1 in the entire ventricles for shock strengths as low as 6.25% of DFT. Furthermore, we observed Φe gradient distributions that were virtually identical, where one configuration had an eight times higher DFT than the other. Thus, a criterion using the Φe gradient in a critical mass of tissue was not found to be reliable in predicting the optimal placement of ICDs. Mechanistically, Φe gradients cannot be used to predict the DFT because they do not relate to the specific processes responsible for defibrillation failure, such as propagated graded responses (Trayanova et al. 2003; Bourn et al. 2006) and tunnel propagation (Ashihara et al. 2008; Constantino et al. 2010). Following the shock, a VEP distribution is established in the tissue, from which the post-shock activations emanate (Trayanova, 2001; Trayanova et al. 2011). It is now well understood that not only Φe gradients but also ventricular tissue structures and tissue anisotropy shape the VEP distribution in the ventricles (Arevalo et al. 2007; Trayanova et al. 2011), which in turn can create or abolish propagating re-entrant waves (Trayanova et al. 1998; Efimov & Ripplinger, 2006). A possible compromise to decrease the computational load would be a two-stage approach in which the epicardial potentials are calculated from a passive torso model and then used as boundary conditions for the active simulation of defibrillation in the ventricles.
Our simulations demonstrated that ICD configurations incorporating epicardial leads had lower DFTs and CVTs than configurations with subcutaneous leads in the tricuspid valve atresia patient in this study. Specifically, two configurations with epicardial leads – one with a left epicardial lead and a right chest can, and the other a posterior epicardial lead and a left chest can – exhibited the lowest DFT and CVT and were thus the optimal ICD configurations tested. Three configurations with subcutaneous leads (one with a single lead and two with multiple leads) were electrically most favourable among subcutaneous lead ICD configurations. The single subcutaneous lead option among these three configurations had a left para-sternal lead and sub-axillary can and corresponded to the commercially available subcutaneous ICD (S-ICD®; Cameron Health Inc., San Clemente, CA, USA; Bardy et al. 2010). Our findings regarding the optimal ICD configuration are clearly specific to this patient, and may not be generalizable to the entire paediatric or CHD population. The depth of the ICD can placement may also play a role in determining how electrically favourable an ICD configuration is. As an example of such placement, we also calculated the DFT for a deeper sub-axillary ICD can location; the results are shown in Supplemental Fig. S8.
In addition to choosing an electrically favourable ICD configuration, the physician may also take additional considerations into account when deciding on which placement option to use. First, the invasiveness of the implant procedure could play a role in decision making, especially when taking into consideration the possibility of multiple ICD and lead exchanges over the CHD or paediatric patient's lifetime (Alexander et al. 2004; Cecchin et al. 2010). Second, complications associated with a particular placement option is an important consideration (Griksaitis et al. 2013). Non-transvenous shock coil failure has been shown to be of particular concern in the paediatric and CHD populations (Radbill et al. 2010). It has been reported that epicardial defibrillation leads are more vulnerable to lead break and physical damage than the thinner pace–sense leads commonly associated with subcutaneous lead placement (with the exception of the S-ICD®, which does not include a pace–sense lead and does not have pacing capacity; Griksaitis et al. 2013). Third, the patient might require pacing, which would rule out ICD configurations that lack pacing capacity. These three issues could be taken together with the predictions of our pipeline to make a decision regarding the best treatment option for the specific patient.
Large DFT and CVT differences were observed between ICD configurations, underlining the importance of choosing the optimal ICD configuration. Furthermore, clinical data evaluating the DFTs of different ICD configurations in paediatric and CHD patients are scarce (Radbill et al. 2012), so physicians cannot currently rely on published reports when deciding which ICD configuration to use in a patient of this cohort. The pipeline and methodology developed in this study presents a novel approach to predicting the optimal ICD configurations before device implantation, a tool particularly important for paediatric and CHD patients who often have contraindications for transvenous lead ICD implantation.
There are several limitations in the modelling methodology presented here. (1) Fibre orientations in skeletal muscles were not represented, and thus the skeletal muscles were modelled as isotropic tissue. Seitz et al. (2008) showed that skeletal tissue anisotropy had a much smaller effect on the electric fields of transthoracic defibrillation shocks than myocardial tissue anisotropy. As ICD shocks have to traverse less muscle tissue than transthoracic shocks, the influence of skeletal muscle anisotropy would be even smaller here than in the case of transthoracic shocks, so we do not expect our findings to be affected by this limitation. (2) Abdominal MRI scans of this patient were not available, so no abdominal ICD locations could be modelled. However, the modelling pipeline enables the modelling of abdominal configurations if abdominal scans are available. (3) Our model lacked a patient-specific representation of the Purkinje system, but featured a generic, cable-based Purkinje representation to simulate sinus rhythm. Since Dosdall et al. (2010) demonstrated that the Purkinje system was not involved in defibrillation mechanisms after short-duration VT or VF, the lack of a patient-specific Purkinje representation does not affect the validity of our findings. (4) It is unknown whether fibre orientations have the same relationship to chamber geometry in the CHD ventricles as in the normal ventricles. In the absence of such knowledge, the methodology used previously in structurally normal hearts was employed in the modelling pipeline to assign the fibre orientations based on the ventricular geometry of paediatric and/or CHD hearts. (5) If paediatric or CHD patients have previous devices implanted, they might not be able to undergo MRI scans, unless the prior devices are MRI compatible. In this case, CT scans could be used instead of MRI scans in our modelling pipeline. (6) The prediction of optimal ICD configurations using the modelling pipeline could not be validated against patient outcomes in this study.
Translational perspective
ICDs with transvenous leads often cannot be deployed in a standard manner in paediatric and CHD patients. Currently, there is no reliable approach to predict the optimal ICD placement in these patients. A pipeline for constructing personalized, biophysically detailed active heart–torso models from clinical MRI scans was developed and applied to a paediatric CHD patient. Optimal ICD placement was determined by conducting patient-specific simulations of shock delivery from different ICD configurations and determining the corresponding defibrillation thresholds. In a patient with tricuspid valve atresia, two ICD configurations with epicardial leads were found to have the lowest defibrillation threshold. We demonstrated that determining extracellular potential (Φe) gradients during the shock – without actually simulating defibrillation – was not sufficient to predict defibrillation success or failure. Using the proposed methodology, the optimal ICD placement in paediatric/CHD patients can be predicted computationally, which could reduce defibrillation energy if the pipeline is used as part of ICD implantation planning.
Additional information
Competing interest
N.A.T. has partial ownership of CardioSolv, LLC. CardioSolv, LLC was not involved in this research.
Author contributions
Conception and design of the experiments: L.J.R. and N.A.T. conceptualized and designed the study, with significant contributions from J.E.C. F.V., L.J.R. and N.A.T. conceptualized and designed the model creation pipeline, with significant contributions from P.J.S. (at Johns Hopkins University, Baltimore). Collection, analysis and interpretation of data: P.J.S. collected and provided the MRI scans. F.V. and L.J.R. constructed the model, with critical input from P.J.S. L.J.R. performed the computer simulations. L.J.R. and N.A.T. analysed the data, with important contributions from J.E.C. (at Johns Hopkins University, Baltimore). Drafting the article or revising it critically for important intellectual content: L.J.R. drafted the overall manuscript, F.V. drafted the model creation sections in Methods, and N.A.T. critically revised the manuscript (at Johns Hopkins University, Baltimore).
This study was supported by National Institutes of Health (NIH) grant R01-HL103428 to N.A.T., and by National Science Foundation (NSF) grant CDI-1124804 to N.A.T.
We are very grateful for the help of Dr Patrick M. Boyle, who created the cable-based representation of the Purkinje system for this model (see Supplemental methods).


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Hotel Guest Rating: 9.2/10
61 Exeter Street
Boston, MA 02116
Hotel Freebies Available*
• Free Internet in Public Areas show dates
Welcome to the The Lenox Hotel
Free Wi-Fi, 24-hour room service and all the extravagances savvy guests search for are offered in a Back Bay location at the star-studded Lenox Hotel.
Hotel Features
Built in 1900, the 11-story Lenox Hotel was once home to Judy Garland and today provides red-carpet amenities in its 214 rooms — expect crystal lamps, high ceilings, luxury bedding and marble baths with luxury toiletries. Guests also enjoy tech-savvy features including iPod docks and free Wi-Fi. Convenience is the name of the game with 24-hour room service, fitness and business facilities and valet parking (for an additional fee). Specialty drinks and organic American cuisine feed guests' palates. The hotel also offers concierge services. Pets are permitted.
Hotel Location
Located two blocks west of Trinity Church, the Lenox Hotel places guests off I-90 and one block from the cafes, restaurants and superb shopping along Newbury Street. Guests appreciate the hotel's walk-friendly perch that's one street from Copley Place and a five-minute stroll from the Hynes Convention Center. Flights land four miles away at Logan Airport.
Guest Favorites
Priceline guests say they find an "old-world" vibe, "outstanding" service and an "excellent" location that's "walking distance to almost everything" at the "immaculate and beautiful" Lenox.
The Lenox Hotel Amenities
- 24-hour front desk
- 24-hour room service
- 24-hour security
- Accessible facilities
- Accessible parking
- Air conditioning
- ATM/Cash machine
- Bell staff/porter
- Buffet breakfast
- Business center
- Business services
- Car rental desk
- Catering services
- Children welcome
- Complimentary coffee in lobby
- Concierge desk
- Conference facilities
- Connecting rooms
- Continental breakfast
- Elevators
- Express check-out
- Family plan
- Full american breakfast
- Full service housekeeping
- Housekeeping - daily
- Interior corridors
- Late check-out available
- Laundry/Valet service
- Lounges/bars
- Meeting rooms
- Non-smoking
- Non-smoking rooms (generic)
- On-site business center
- Parking fee managed by hotel
- Pets allowed
- Photocopy center
- Public address system
- Restaurant
- Room service
- Safe deposit box
- Security
- Storage space
- Turndown service
- Valet parking
- Valet same day dry cleaning
- Wakeup service
- Wireless internet connection in public areas
Hotel Guest Reviews of the The Lenox HotelOur hotel ratings and reviews are from real hotel guests. Priceline.com ensures that its reviews are guests-only by proactively sending hotel surveys to customers after they've completed their hotel stays. In the post-stay surveys, priceline.com hotel customers are asked a number of questions about their stay and the hotel. On a scale of 1-10 with 10 being the best, the survey asks guests to rate their overall experience and specifically rate the hotel's cleanliness, staff and location. Priceline.com does not allow site visitors to post unsolicited hotel reviews.
Sort by: All Travelers | Business Traveler(14) | Solo Traveler(13) | Traveling as Couple(48) | Family with Young Children(12) | Family with Teens(6) | Senior Traveler(2) | Group Traveler(5)
Verified Hotel Guest from New York, NY
July 19, 2016
July 19, 2016
Beautiful historic hotel. They kept the elegance of a past era but updated. I loved that it was in a perfect neighborhood with access to everything, tons of restaurants and shopping, subway a short block away. I Could not have chosen a better hotel.
Timothy from Clemmons, NC
July 16, 2016
Family Traveling with Young Children
July 16, 2016
Family Traveling with Young Children
The hotel was superb in every way! Exquisite rooms and lobby area and the staff were incredible!
Robert from St Petersburg, FL
July 10, 2016
Solo Traveler
July 10, 2016
Solo Traveler
This guest did not leave comments about this hotel.
Verified Hotel Guest from Burleson, TX
June 23, 2016
June 23, 2016
Location and staff were excellent.
Verified Hotel Guest from Wrightsville Beach, NC
June 14, 2016
Senior Travelers
June 14, 2016
Senior Travelers
This guest did not leave comments about this hotel.
Verified Hotel Guest from Atlanta, GA
June 10, 2016
Solo Traveler
June 10, 2016
Solo Traveler
The staff was very friendly and attentive. Beautiful public spaces and ideal location.
Bathroom was very cramped for this level of hotel and the door was on an automatic closer which closed it halfway and was constantly in the way. Very nice finishes but too crowded with no place to put a dopp kit.
Nicole from Tampa, FL
June 9, 2016
Family Traveling with Young Children
June 9, 2016
Family Traveling with Young Children
Staff were amazing from the moment we arrived with our luggage to the moment we left.
In room dining. Food was cold. Coffee not as fresh as I would have liked.
Verified Hotel Guest from New York, NY
June 1, 2016
June 1, 2016
Great location. Charming character.
Rooms on the small side -- was fine.
Verified Hotel Guest from Green Brook, NJ
May 31, 2016
May 31, 2016
This guest did not leave comments about this hotel.
Verified Hotel Guest from Birmingham, AL
May 30, 2016
May 30, 2016
Location and staff are great
Size and quality of the room were extremely disappointing for 4.5 stars
Reviews of The Lenox Hotel
(1 - 10 of 105 reviews)
(1 - 10 of 105 reviews)
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Young - Georgie Martin
Fri, Jan 23rd, 2004
Posted in Obituaries
Posted in Obituaries
Georgie Martin Young, 87, of Canton, a retired farmer, died January 15, 2004 at Green Lea Manor Nursing Home in Mabel following a short illness.
Born Nov. 17, 1916, to Elbert and Stella Young on the family farm. He graduated from Canton High School and attended the University of Minnesota. On June 4, 1941, he married Irene Jones. They farmed on the home farm where he raised Belgian horses, and after moving into Canton, he kept close ties to the farm. His wife died Feb. 4, 1992. Mr. Young was a longtime member and past elder of Canton-Scotland First Presbyterian Church. He served on the Elliota School Board and was a member of the Harmony-Canton Saddle Club for many years. Survivors include a daughter, Joanne (Calvin) Henry of Marion, Iowa; a son, William of Canton; nine grandchildren; and seven great-grandchildren. He was preceded in death by a son and a sister. The funeral for Georgie Martin Young was January 19, 2004 at First Presbyterian Church in Canton, with the Rev. Jim Saife officiating. Burial was in Elliota Cemetery in rural Canton. Lindstrom Funeral Home in Harmony was in charge of arrangements.