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text:
Events View all Events
Propaganda Cheltenham - Shipwreck Party!
Moo Moo Cheltenham, Cheltenham
Thu 28th Jul, 10:00pm Moo Moo Cheltenham, Cheltenham
Propaganda Cambridge - Shipwreck Party!
Fez Club Cambridge, Cambridge
Fri 29th Jul, 10:00pm Fez Club Cambridge, Cambridge
PEACE (DJ Set) at Propaganda Birmingham
O2 Academy Birmingham, Birmingham
Fri 29th Jul, 10:30pm O2 Academy Birmingham, Birmingham

subset: commoncrawl


text:
MTV: Stay tuned, 4
Advertising Agency: Loducca, São Paulo, Brazil
Creative Director: Guga Ketzer
Art Directors: Daniel Poletto, Kika Botto, Carlos Thunm
Copywriters: Rodrigo Senra, Andre Godoi
Photographer: Raul Krebs
7 comments
it requiers a better photography for such client as MTV.
Idea is just "workable". But poorly executed. Should be colourful, smart... wtf* is this sky? scopes should be shinning too. Dont like the scenaries neither the models.
i miss brazil's old creatives... hope some new stuff rise from now on.
dude, brand communication for mtv in brazil is made this way. looks natural, without photoshop, like real people, like real footage, real pictures. that´s the way they work over here to this client. you have other ways and other mtvs around the world. so, i guess, different ways of brand communication.
nice concept...
but there is something called BRAND PERSONALITY which is missing in this ad
have to agree with the guest commenters..............the models look like zombies!


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Hi all,
I am constructing a Java program which acts as shop managing system. Staff run the software and it collects the information from a file which is named data.txt. The information contained in this file is layed out as so:
Item name, Item price
I need to use the split method to seperate the name and the price and probably store them in an ArrayList, however I am not confident with the split method.
***This is the split method from the java.lang.String class***
Here is the code below. I have written in red where the problem is.
Any help is appreciated!Code:import java.util.HashMap; import java.util.ArrayList; public class CoffeeShop { private HashMap<String, SalesPerson> employees; private ArrayList<Category> categories; private Reader menu; public CoffeeShop() { employees = new HashMap<String, SalesPerson>(); categories = new ArrayList<Category>(); menu = new Reader("data.txt"); String[] items = menu.split(","); Error here...and don't know what to do. } }


text: AdChoices Terms of Use Privacy Policy Hide TOP 10 Top 10 Entertainment Buying A Next-Gen Console © Warner Bros. Interactive Entertainment Buying A Next-Gen Console 10 Reasons E3 Gave You To Finally Go Next-Gen Toby McCasker June 27, 2014 Share Tweet 0 Shares So Microsoft's Xbone and Sony's Playstation 4 have been out for months now, and Nintendo's struggling WiiU has been out even longer. We should be psyched, but we are instead bummed. Many of us haven't even bothered to go next-gen yet, because uh, someone forgot to tell these people that new consoles also need new games to play, not just slightly better-looking rehashes of stuff put together for yestergen's tech. Earlier this month, E3 set about changing our minds in ten big ways, though. Here are 10 reasons you should think about buying a next-gen console. Start With #10 TOP 10 9 8 7 6 5 4 3 2 1 PlayStation Video Games Xbox e3 Comments Share your opinion Your name More Like This Entertainment and Celebrities If You Have A Playstation These Are Not The Games You Are Looking For Read More Entertainment and Celebrities These Games Are E3's Bread And Butter And For Good Reason Read More Entertainment and Celebrities If You Have An Xbox These Are Not The Games You Are Looking For Read More Entertainment News Trending News: The Fallout 4 Trailer Is So Good They Couldn't Wait Until E3 Read More Trending Stealth Killing, England In The 1800s, Gangs - What's Not To Love?! Read More Entertainment and Celebrities Fatalities Have Never Been This Hardcore With New-School Kano In Mortal Kombat X Read More Around the Web Special Features Special Feature The Ultimate Guide To Hooking Up Online Read More Guy Gear The Best Watches Under $500 Read More


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Bayers named Colonels athletic trainer
Published: Wednesday, August 31, 2011 at 11:29 a.m.
Last Modified: Wednesday, August 31, 2011 at 11:30 a.m.
The Nicholls State University Athletic Department announced the hiring of Krista Bayers to the position of head athletic trainer.
Bayers, a native of San Andreas, Calif., arrives in Thibodaux by way of Livingstone College in Salisbury, N.C., where she served as assistant athletic trainer since September of 2010. Bayers worked with a wide array of sports during her time at Livingstone.
Prior to her stint with the Blue Bears, Bayers was the primary graduate assistant for the UNLV football team, where she worked with current Colonels coaches Keith Uperesa and Mario Jeberaeel.
During her time with the Rebels, Bayers earned her master's degree in kinesiology.
"I'm very excited to be joining Nicholls Athletics," Bayers said. "I have connections here and know I'll be working with some great people."
Bayers, a NATABOC certified athletic trainer and member of the National Athletic Trainers' Association, received her bachelor's degree in kinesiology at Fresno State University. At Nicholls, Bayers will have oversight over all aspects the athletic training program. She will be primarily responsible for covering football, men's basketball and baseball.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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TeamVic Softball SSA 12 Years and Under Boys and Girls National ChampionshipsSunday, November 13, 2016
Trial Information:
1st Trial Date: Sunday 24th July 2016,
Time: 10:00am – 1:00pm
Venue: Northern Districts Softball Club, Mill Park Reserve, Morang Drive, Mill Park (Melway Map 9 J-1)
2nd Trial Date: Sunday 31st July 2016,
Venue: Waverley Softball Club, Jells Park, Waverley Road, Glen Waverley (Melway Map 71, K6)
Selection Guidelines: Please click here to view the selection guidelines for this team.
12 Years and Under - Born 2004, 2005 or 2006. Please note, students turning 9 or 13 years in 2016 are ineligible.
Registrations Close: Tuesday, 19 July 2016
CHAMPIONSHIP VENUE AND DATES : Melbourne (Werribee Softball Association), VIC
13 - 18 November, 2016
CHAMPIONSHIP VENUE AND DATES Melbourne (Werribee Softball Ass), VIC
1st Trial Date: Sunday, 21 February, 2016
Time: 11:00am – 2pm
Venue: Werribee Softball Club, Presidents Park, McGrath Road, Wyndham Vale, (Melway Map 205, C4)
Time: 11:00am - 2:00pm
Venue: Frankston Softball Club, Robinson's Park, Robinson's Rd., Frankston VIC 3199
AGE ELIGIBILITY 17 Years and Under as at 30 June 2016
Registrations have now closed. No student will be allowed to trial if they did not register online.
CHAMPIONSHIP VENUE AND DATES Melbourne (Waverley Softball Ass), VIC,
April 30 - 7 May 2016
2nd Trial Date: Sunday, 28 February, 2016
Results of the previous Softball Championships can be found on the School Sport Australia website.
2016 Team Vic Girls 17 Years and Under Softball Team
2016 Team Vic Boys 17 Years and Under Softball Team
2015 SSV Team Vic 12 years and under Girls Softball State Team Captain's Report
2016 SSV Team Vic State 17 years and under Boys Softball Team Captain's report
2016 SSV Team Vic State 17 years and under Girls Softball Team Captains' report
2015 SSV Team Vic 12 years and under Boys Softball State Team Captains' Report
School Sport Australia Codes of BehaviourCodes of Behaviour to be adhered to by all SSV Team Vic state team members, their parents/guardians and team officials
School Sport Australia Sport InformationSchool Sport Australia Dates, Information, Rules, Policies, Guidelines and Results
Created on: May 31, 2011
Last modified: July 22, 2016
© Copyright 2011 School Sport Victoria Site Map | Privacy | Disclaimer| Contact Us


text:
All Seven of Them? 'Bad Words' Trailer
By Steven Lloyd Wilson | Trailers | January 9, 2014 | Comments ()
The trajectory of my interest in a film has never so steeply gone from zero to forty-two. Allow me to explain. I mistakenly read the actor as Jason Schwartzman and clicked play with the complete lack of enthusiasm for yet another Wes Anderson movie. Then Jason Bateman started viciously swearing at children and I rediscovered a joy I never knew I had missed.
Here's the green band trailer:
And just for completeness sake, here's the red band trailer, it's not much different but dialogue is a bit saucier:
Oh beautiful trailer, you had me at Jason Bateman combines Bad Santa with children's spelling bees. Bateman always plays the straight guy who the oddball throws jokes off of. But the sheer deadpan he cultivated for those roles is also perfectly suited for coldly and calmly annihilating people with words. I love that trailer so much, I don't even care if all the good parts are in it. Those two minutes could make ninety minutes of gorillas taking LSD entertaining enough to pay for the ticket.
Here's the obligatory plot summary:
Jason Bateman (Identity Thief) makes his feature directorial debut with the subversive comedy Bad Words. Mr. Bateman stars as Guy Trilby, a 40-year-old who finds a loophole in the rules of The Golden Quill national spelling bee and decides to cause trouble by hijacking the competition. Contest officials, outraged parents, and overly ambitious 8th graders are no match for Guy, as he ruthlessly crushes their dreams of victory and fame. As a reporter (Kathryn Hahn of We're the Millers) attempts to discover his true motivation, Guy finds himself forging an unlikely alliance with a competitor: awkward 10-year-old Chaitanya (Rohan Chand of Homeland), who is completely unfazed by Guy's take-no-prisoners approach to life.
Really? You need to drop titles for Jason Bateman and Kathryn Hahn and you pick Identity Thief and We're the Millers?
Pajiba Love Express
Here's some Daveed Diggs for you. On Daveed Diggs' digs, actually. That man does things with clothes that should not make sense, but are absolutely perfect. (Go Fug Yourself)
Woody Allen has "so moved on" from his daughter's accusations and says he never even thinks about it. He equates her words about him to a bad review he won't read and comments on how wacky it is that Mia Farrow is his mother-in-law. He is the worst. (Celebitchy)
Not The Worst but still very gross: Leonardo DiCaprio and his
Here are 5 under-the-radar shows. I had never even heard of the first two. (Uproxx)


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Originally posted on Fox Sports Arizona | By STEVE RIVERA | Last updated 11/4/13
TUCSON, Ariz. -- Arizona coach Rich Rodriguez has gone on the record saying he has no problem going "for it" on fourth down with the Wildcats in opponents territory. He's done it more than a few times over the last couple of seasons. Actually, more often than not. On Saturday at California, he didn't, believing his senior place-kicker Jake Smith might have enough leg to hit it a field goal from 50-plus yards. Smith was 50-50 from 50-plus -- hitting a 53-yarder and missing from 55. "Hopefully they will let me try more," Smith said. "It's about coach having confidence in me." On his personal-best 53-yarder, Smith's kick cleared the crossbar with about three yards to spare. On his 55-yard miss, he came up about two yards short. "I knew as soon as I hit it I got under it," Smith said of the miss. "As soon as you hit it ... you know how it feels. "Missing from 55 (yards) is not OK with me, but it's OK with me (more) than missing a shorter one." Rodriguez said he liked what he saw from Smith, who has been good on his kickoffs all season. But he's only 9 for 13 on field goals, missing some seemingly easy ones. His role could be magnified Saturday when the Wildcats host No. 16 UCLA in a pivotal Pac-12 South game. Both teams are 3-2 in the conference and 6-2 overall. "I don't want to say he's been uneven, but he's gotten better," Rodriguez said. With John Bonano handling kicking chores last year, Smith sat out the season while recuperating from a knee injury. "I still don't think I'm there," he said of being fully healed. "There's another level I can get to, where I'm trying to get to." But he does feel he can hit from beyond 50 more often. Of course, it will be up to Rodriguez, who likes to gamble on fourth down rather than take a chance at the three points. "I don't think I have that pull just yet," he said when asked about lobbying for longer kicks. "I just go out there when I'm kind of told to go out there. Would I like to go out there and try a longer one? I wish I would; I have confidence I can make them and help the team out." Smith said in practice and warm-ups he's hit from 60 yards at Arizona Stadium. He said he has enough leg for a 55-yarder. "I just want to win. I don't care how we do it," Smith said. Arizona also got a strong effort Saturday from sophomore punter Drew Riggleman. He punted eight times for a 41.4 yards per kick average, had four kicks downed inside the 20 and had a career-long 56 yarder. "He's been pretty solid (all year)," Rodriguez said. Quarterbacking clinic Rodriguez said he didn't have a chance to see former UA quarterback Nick Foles throw for seven touchdowns against Oakland, but he did see the highlights. Rodriguez came a year after Foles finished his senior year. "Nick put on a clinic," he said. "I got to see some of his highlights when he was here. I said he'd be great in anyone's offense. Just like Matt Scott (who replaced Foles at Arizona)." Scott is on the practice squad of the Jacksonville Jaguars. Extra points Special teams player Trevor Ermisch suffered a season-ending knee injury on Saturday in a non-contact situation, Rodriguez said. It occurred on the opening kickoff and apparently happened when he was trying to make a cut. He's expected to have surgery to repair his ACL. Rodriguez called Ermisch, a junior, the team's most productive special teams player. Senior linebacker Jake Fischer did not practice on Sunday after missing the Cal game with a knee injury, but he is expected back against UCLA. The UCLA game will kick off at 8 p.m. and be televised by ESPN. Arizona announced that its Nov. 16 game vs. Washington State will kick off at noon and be televised by the Pac-12 Networks. Rodriguez said his preference is to play early games, in part so he can have the rest of the day to watch other teams play later in the day.
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michael07 replied to michael07's topic in Ford Fiesta ClubThanks guys. I will ask my friend to do the translation as soon! It works in all engine.
michael07 posted a topic in Ford Fiesta ClubHello everyone. If anyone is interested in mounting the button to switch off the ESP Please note that is possible because the Fiesta is set up. This Guide My site is in Italian, but if you're interested, will translate into English for you. regards ESP Switch
Your italian is poor like my english!! :P
Thanks to all. In Italy we have a few versions of the Fiesta, those sports do not exist. There are no wheels of 17 inches. I mounted the wheels of the MSW model 11 of 16 inches. The cost for 4 wheels is € 396. If someone want a photogallery on the Italian community we are happy to accept him! :-) We like your Fiesta! This is our logo:
michael07 posted a topic in Ford Fiesta ClubHi, this is my Ford Fiesta mk7 1.2 nero panther titanium. I'm italian and you can see other pic here... Fiesta Vs Oper Corsa!
michael07 posted a topic in New Member IntroductionsHello guys, my name is Nazario and I am Italian. I bought the new Fiesta two months ago: here are the photos. I also created a community in Italy. Look at the link. Greetings to all! Ford Fiesta Italia Community


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From CBS News Director of Political Coverage Steve Chaggaris:
Sen. John Kerry, D-Mass., is set to endorse Barack Obama at an 11am rally in Charleston, S.C. today, according to Democratic sources.
Kerry, the 2004 Democratic presidential nominee, lost to George W. Bush but remains a high-profile figure in the party and also maintains a large mailing list through his political organization that will be used to help Obama.
The question remains how much of a boost this endorsment will be to Obama in South Carolina, where the announcement is happening, or in other states throughout the primaries.
In 2004, former Vice President and 2000 Democratic presidential nominee Al Gore endorsed Howard Dean before the Iowa caucuses, only to watch Dean lose there.
Also of note, today's endorsement is happening in South Carolina, a state Kerry lost both during the primaries and the general election in 2004.
Kerry to Endorse Obama
© 2008 CBS Interactive Inc. All Rights Reserved.


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Founded in 2001, The Prem Rawat Foundation is a U.S.-based nonprofit organization that strives to address the fundamental human needs of food, water and peace so that people can live with dignity, peace and prosperity. more
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New Jersey Golfers Defy Weather to Raise Funds for PEP
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After dinner, avid golfer and ardent ...
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After dinner, avid golfer and ardent spokesman for TPRF, Charan Anand gave an inspiring presentation to the attendees.The golf tournament itself was rescheduled for Sunday, May 22, at the Chapel Hill Golf Course, a private country club set in pleasant landscaped grounds. The day dawned clear with temperatures into the high 80's. Ten teams competed to dethrone last year's champions. As evening fell, a new team emerged to claim the 2011 trophy. The hungry golfers and guests enjoyed a deli buffet, and the evening ended with a brief presentation on TPRF by Angelina Stevens and Charan Anand.
Crystal Springs Golf Tournament
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noel fielding is an english comedian, actor, artist and musician. He is co-creator of the mighty boosh, luxury comedy and appears on never mind the buzzcocks. he is also the foundER of loose tapestries formed with kasabian's sergio pizzorno.
Noel on Room 101
Noel will be joining actress Joanna Scanlan and all round legend Ian Wright on tomorrow's episode of Room 101 with Frank Skinner. Watch it live at 8:30pm on BBC One.
Noel on Conan
Noel will be Conan O'Brien's guest tomorrow at 11PM EST on TBS
Travelman with Richard Ayoade
Noel and Richard Ayoade will be together again in the new series of #Travelman where they spend 48hours in Copenhagen, Denmark
You can catch this on Tuesday 18th at 8:30pm on Channel 4
Noel's on Tonight Show with Jimmy Fallon
You can catch Noel on The Tonight Show with Jimmy Fallon, tomorrow at 11:35ET


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To review the existing human controlled intervention studies of vitamin D as adjunctive therapy in settings of infection and provide recommendations for design and implementation of future studies in this field on the basis of the evidence reviewed.
We conducted a systematic review of randomized controlled clinical trials that studied vitamin D for treatment or prevention of infectious diseases in humans. Studies from 1948 through 2009 were identified through search terms in PubMed and Ovid MEDLINE.
Thirteen published controlled trials were identified by our search criteria. Ten trials were placebo controlled, and 9 of the 10 were conducted in a rigorous double-blind design. The selected clinical trials demonstrated substantial heterogeneity in baseline patient demographics, sample size, and vitamin D intervention strategies. Serious adverse events attributable to vitamin D supplementation were rare across all studies. On the basis of studies reviewed to date, the strongest evidence supports further research into adjunctive vitamin D therapy for tuberculosis, influenza, and viral upper respiratory tract illnesses. In the selected studies, certain aspects of study design are highlighted to help guide future clinical research in the field.
More rigorously designed clinical trials are needed for further evaluation of the relationship between vitamin D status and the immune response to infection as well as for delineation of necessary changes in clinical practice and medical care of patients with vitamin D deficiency in infectious disease settings.
The link between vitamin D deficiency and susceptibility to infection has been suggested for longer than a century, with the early observation that children with nutritional rickets were more likely to experience infections of the respiratory system, leading to the coining of the phrase "rachitic lung" (1). The isolation of vitamin D3 from cod liver oil, which was used to treat tuberculosis (TB) in the 1930s, led to its widespread use in TB treatment and prevention, until the introduction of antiinfective chemotherapy in the 1950s (2). More recently, epidemiologic studies have demonstrated strong associations between seasonal variations in vitamin D levels and the incidence of various infectious diseases, including septic shock (3), respiratory infection (4), and influenza (4,5).
Our understanding of vitamin D metabolism and its extraskeletal functions has improved considerably during the past 3 decades. The discovery that vitamin D receptor (VDR) and 1α-hydroxylase, the enzyme necessary for conversion of vitamin D into its active form, are present in cells of the immune system, including circulating mononuclear cells (6,7), has revolutionized the field of vitamin D immunology. Moreover, the discovery of nonskeletal functions of vitamin D has reinvigorated interest in vitamin D as a potential modulator in a variety of disease states (8–10). Recent studies have demonstrated that vitamin D regulates the expression of specific endogenous antimicrobial peptides in immune cells (11); this action leads to a potential role for vitamin D in modulating the immune response to various infectious diseases.
These findings highlight the need to refine our understanding of the nonskeletal functions of vitamin D through future controlled studies of vitamin D supplementation and clinical outcomes in specific disease states. In this report, we focus on reviewing the existing human controlled intervention studies of vitamin D as adjunctive therapy in settings of infection and provide recommendations for design and implementation of future studies in this field.
The pioneering work by Rook et al (12) and Crowle et al (13) in the 1980s demonstrated that vitamin D enhanced bactericidal activity of human macrophages against Mycobacterium tuberculosis, the causative agent of TB. This discovery led to a new era of interest regarding the role of vitamin D in determining pathogenesis and the immune response to bacterial pathogens. Liu et al (11) provided a key mechanism to how vitamin D may enhance innate immunity. This group demonstrated that stimulation of macrophage-bound Toll-like receptor 2/1 complex by M tuberculosis-derived antigens upregulates the expression of both VDR and CYP27b1, an enzyme that converts 25-hydroxyvitamin D (25-OHD) to its active 1,25-dihydroxyvitamin D [1,25-(OH)2D] form. Intracellular 1,25-(OH)2D generated though action of CYP27b1 then interacts with the VDR and leads to induction of the antimicrobial peptide cathelicidin and killing of intracellular M tuberculosis (11). In the state of vitamin D deficiency, the infected macrophage is unable to produce sufficient 1,25-(OH)2D to upregulate production of cathelicidin.
Although this antimicrobial mechanism of vitamin D has been demonstrated only in macrophages infected with M tuberculosis, it is also well known that cathelicidin has broad-spectrum activity against a wide variety of other pathogens, including gram-negative and gram-positive bacteria, viruses, and fungi (14). Vitamin D is also known to regulate the expression of β-defensin (15), another antimicrobial peptide with multiple effector functions within the immune system. Endoscopic studies in humans have demonstrated that β-defensin is secreted in the gastric mucosa after infection by Helicobacter pylori (16) and may therefore constitute a major aspect of immune defense against this bacterial pathogen at the mucosal surface. Additional studies also suggest that vitamin D may cause upregulation of the oxidative burst in activated macrophages (17), thus augmenting another multipurpose mechanism of bacterial killing. Studies of VDR polymorphisms in humans support the hypothesis that variability in vitamin D status and host genes encoding vitamin D-responsive elements affect the immune response to bacterial pathogens other than M tuberculosis (18,19). Therefore, much of what we learn from the interaction between host vitamin D status and TB infection can enhance our understanding about the immunomodulatory properties of vitamin D in other bacterial diseases, although more research is needed to help generalize this information to other clinical settings.
The seasonality of viral respiratory tract infections such as those caused by influenza virus ("the flu") and rhinovirus ("the common cold") has been observed in both popular (20) and scientific literature (21) and is understood to be a major contributor to seasonal variations in human mortality (21). On the basis of these observations, Cannell et al (5) have argued that vitamin D status may be a contributor in determining the population susceptibility to seasonal epidemic outbreaks as well as the degree of associated morbidity and mortality, thus likely augmenting the effects of increased indoor confinement and circulating reservoirs of respiratory viruses in wintertime. It is well known that often the exuberance of the host immune response, rather than the viral pathogen itself, determines the clinical severity and mortality risk associated with viral diseases such as influenza (22,23). Vitamin D modulates cytokine profiles in animal models of autoimmune disease through limiting excessive production of proinflammatory cytokines, such as tumor necrosis factor α and interleukin-12, and thus leading to suppression of inflammation (24). In addition, the antimicrobial peptides cathelicidin and β-defensin, regulated in part by vitamin D (11,15), also have a major role in the immune defense of the respiratory system through direct inactivation of viral pathogens (25) and increased recruitment of phagocytes (26). Collectively, these studies support the hypothesis that optimal vitamin D status of the host may contribute key immunoregulatory functions in settings of viral respiratory infection by downregulating overly exuberant (and thus toxic) cytokine responses, while allowing for improved clearance of various microbial species (5).
The relationship between vitamin D status and human immunodeficiency virus (HIV) infection is also capturing more attention in recent literature. At this point, it is uncertain whether vitamin D status is associated with particular outcomes of HIV-related disease and potential for immunologic recovery with antiretroviral therapy. Recent studies, however, do suggest that there may be an increased prevalence of vitamin D deficiency in HIV-infected patients in comparison with uninfected hosts, although these data remain conflicting (27,28). Laboratory models of HIV infection have demonstrated that pretreatment of human monocytes and macrophages with 1,25-(OH)2D prevents HIV infection in certain cell lines (29), while increasing HIV replication in others (30). Another recent study demonstrated that cathelicidin, the antimicrobial peptide regulated in part by vitamin D, may directly inhibit replication of HIV (31). Therefore, the relationship among vitamin D metabolism, HIV disease, and HIV therapy appears complex, and additional studies are needed to help interpret the clinical significance of thus-far conflicting data on this topic.
Information regarding potential immunomodulatory roles of vitamin D in settings of other infections, such as diseases caused by fungal, protozoal, or parasitic organisms, is limited. There is a growing understanding, however, that the vitamin D status of the host may affect the overall bias of the host immune response, in which vitamin D repletion appears to favor a Th2-based cytokine profile that is responsible for the observed positive effects of vitamin D therapy in animal models of autoimmunity (24). This background of circulating cytokines is also important for maintaining effective protection and control of various extracellular pathogens—specifically, parasitic, protozoal, and some fungal infections (32,33). These findings, however, appear counterintuitive to what is known about vitamin D-mediated effects on immune responses to intracellular pathogens such as M tuberculosis, in which effective Th1-driven granuloma formation favors containment of latent TB infection and prevention of progression to active TB disease (34). Therefore, more information is needed to help understand the balance among cytokine responses, host vitamin D status, and subsequent host-pathogen interactions with regard to other classes of infectious agents.
We conducted a systematic review of randomized controlled clinical trials that investigated the relationship between vitamin D therapy and clinical outcomes related to infectious diseases in humans. We reviewed the medical literature in PubMed and Ovid MEDLINE from 1948 through 2009, using combinations of search terms including the following: "vitamin D2, ergocalciferol, vitamin D3, cholecalciferol, vitamin D analogue, vitamin D, rickets, infection, immunity, treatment, tuberculosis, upper respiratory infection, influenza, bacteria, virus, protozoa, helminth, fungi, trial, placebo, randomized." No database restrictions were used. Resulting abstracts were screened, and cross-references were used to identify additional publications. Studies focusing on vitamin D supplementation as adjunctive therapy in cancer or autoimmune disease, studies conducted in vitro only or in animal models, studies with non-English manuscripts, studies lacking an adequate control arm, and studies of vitamin D given as part of combination micronutrient supplementation protocols were excluded.
We found 13 controlled trials that met our search criteria (35–47) (Table 1). Ten trials were placebo controlled (35–37,40,42–47), and 9 of the 10 were conducted in a double-blind design. Five of the 13 trials (35–39) addressed vitamin D supplementation in patients with bacterial infection, with 4 of the 5 trials evaluating vitamin D as adjunctive therapy in patients with various forms of TB infection. Seven trials (40–45,47) were predominantly focused on vitamin D in subjects with viral infections, and 1 trial (46) was conducted in subjects with schistosomiasis, a helminth infection.
The selected clinical trials demonstrated considerable heterogeneity in baseline patient demographics, sample size, and vitamin D intervention strategies. Four of the 13 trials were conducted in pediatric populations (38,41,45,46), whereas 3 other trials were in either postmenopausal (42) or elderly patients (39,43). Sample size ranged from 24 subjects in a pediatric TB trial (38) to 3,444 subjects participating in a study of vitamin D and infection in elderly persons (43). Comorbid conditions also varied among the study populations, with inclusion of some HIV-infected patients in a large TB treatment trial (35) and 1 study being conducted exclusively in patients receiving hemodialysis (40).
Seven of the 13 trials specified whether ergocalciferol (vitamin D2) or cholecalciferol (vitamin D3) was used (35,36,39,42,43,45,47); cholecalciferol was favored over ergocalciferol in all but 1 study (36). Vitamin D replacement strategies varied in frequency and dose of therapy, ranging from 40 IU of vitamin D3 given daily for 20 years to 100,000 IU of vitamin D3 given bimonthly for 12 months (Table 2, Table 3, and Table 4). Three studies used high-dose vitamin D repletion regimens, such as 3 doses of 100,000 IU given during an interval of 8 months (35), 60,000 IU administered weekly for 6 weeks (41), or 600,000 IU given during a 12-month period (45). Two (35,45) of the 3 trials favoring rapid high-dose repletion of vitamin D stores are also the most recently published studies in the group, both appearing in print in 2009. The total dose of vitamin D given to the intervention group of each of the studies differed notably, and our analysis of study outcomes (Table 1) revealed no clear trend toward positive study results favoring either long-term daily repletion or bolus replacement.
Six of the 13 clinical trials (35,36,38,42,45,47) provided information regarding the effectiveness of their selected repletion strategy by reporting baseline and follow-up 25-OHD or 1,25-(OH)2D levels in the intervention group in comparison with control or placebo groups (Table 2, Table 3, and Table 4). Eleven of the 13 studies enrolled patients irrespective of baseline vitamin D status. In contrast, 1 study included only patients with a baseline 1,25-(OH)2D level below the reference range (40), and another study excluded patients with evidence of severe vitamin D deficiency, defined as a baseline serum 25-OHD level <12 ng/mL (45). Of note, serious adverse events, such as clinically relevant hypercalcemia as a result of vitamin D supplementation, were rare across all studies. Two of the 13 trials (40,42) reported instances of hypercalcemia in a total of 3 study subjects, necessitating a decrease or discontinuation of study medication.
Five human trials of vitamin D replacement as treatment or prevention of bacterial disease have attempted to translate the mechanism of vitamin D-mediated macrophage activation to the human host (Table 2). Four of the 5 studies were conducted in TB-infected patients and yielded mixed results. Although the outcome of a translational study done by Martineau et al (36) was encouraging, inasmuch as administration of a single dose of 100,000 IU of ergocalciferol to purified protein derivative-positive contacts of active TB cases improved their immunologic control of bacille Calmette-Guérin (an M tuberculosis surrogate) in the peripheral blood, other trials focusing on clinical end points related to TB treatment have generated conflicting results (35,37,38). Two of the 3 clinical TB studies, by Morcos et al (38) and Nursyam et al (37) (Table 2), demonstrated a positive outcome. Morcos et al (38) reported a benefit of increased weight gain and faster resolution of TB symptoms in children treated with 1,000 IU of vitamin D daily as an adjunct to standard TB therapy. Nursyam et al (37) demonstrated significantly higher rates of sputum conversion to culture negativity in the group treated with 10,000 IU of vitamin D daily for 6 weeks in comparison with placebo. Both studies, however, failed to report baseline or follow-up serum 25-OHD levels for either the intervention or the control group, leaving uncertainty about the adequacy of repletion in each case. Although Morcos et al (38) did report 1,25-(OH)2D levels before and after vitamin D treatment (Table 2), these may not provide an adequate refection of overall vitamin D status of the study subjects (48).
In contrast, a 2009 trial of vitamin D therapy in patients with TB reported by Wejse (35) found a significant increase in serum 25-OHD levels in the intervention group receiving 100,000 IU of vitamin D at baseline, 5 months, and 8 months of TB therapy. The author reported that levels of 25-OHD increased from 31 ng/mL at baseline to 41 ng/ mL and 39 ng/mL at 2 and 8 months of follow-up, respectively. Perhaps surprisingly, however, similar 25-OHD levels were reported at baseline, 2 months, and 8 months in the placebo group (35) (Table 2); this observation suggests that the vitamin D dose given to the intervention group was not sufficient to increase 25-OHD levels beyond what would be noted with TB treatment alone. Hence, interpretation of the data is difficult. Additional variables, such as increased exogenous intake of vitamin D irrespective of group assignment or an independent effect of improving nutritional status with TB therapy, may also be confounding the results of the study, which found no difference in TB-related clinical outcomes between the 2 study groups (35). Recruitment and follow-up for the study took place during the course of 24 months, and it is unclear whether seasonal alterations in vitamin D status affected any study outcomes (35).
In the last trial included in Table 2, Kawaura (39) reported a lower incidence of infection with H pylori, the bacterial agent of peptic ulcer disease, in elderly women receiving vitamin D supplementation of 40 IU per day for 2 decades versus control subjects receiving no supplement. Although the study is hypothesis-generating for future investigations in this field, it is hampered by its primarily retrospective design, limited sample size (N = 34), poor repletion potential of the very low vitamin D dose selected for the study, and failure to document baseline and follow-up vitamin D status in either the control or the intervention group.
Therefore, the currently available data from studies in humans regarding the potential value of vitamin D as adjunctive therapy in bacterial infection remain conflicting. Three of the 4 TB trials, and the 1 trial of vitamin D therapy to prevent H pylori-related gastrointestinal disease, demonstrated positive outcomes, although these studies were hampered by major limitations, such as poor sample size and limited information regarding the effectiveness of the repletion strategy. The most recent and the most rigorously designed trial of the series, reported by Wejse (35), demonstrated no clear benefit of adjunctive vitamin D therapy in TB treatment. As discussed in the foregoing material, vitamin D administered at doses higher than the total of 300,000 IU given to the intervention group in this study, along with careful attention to potential confounding factors affecting vitamin D levels in the placebo group, may be necessary to improve the statistical power of future studies. More prospectively designed, intervention-based trials are needed for further evaluation of the relationship between adequate vitamin D repletion and treatment or prevention (or both) of bacterial infections such as TB.
Although information from laboratory and animal models of viral infection in settings of vitamin D deficiency is becoming more available, few trials in humans have been performed to help translate these data into potential clinical applications. Our search identified 7 controlled trials concerning outcomes related to human viral infections (Table 3).
Four of the 7 aforementioned studies evaluated the frequency of respiratory tract infection or influenza in vitamin D-treated patients in comparison with control subjects (41–43,47). An early trial by Rehman (41) most closely resembles a case-control study; 27 children were selected on the basis of a clinical history of recurrent respiratory or antibiotic-requiring illness and paired with age-matched control subjects documented to be free of recurrent infection. Subsequent analysis revealed the recurrent illness group to have a much higher prevalence of subclinical rickets (that is, pediatric vitamin D deficiency) and decreased recurrence of respiratory infection after a course of aggressive vitamin D repletion, given as 60,000 IU weekly for 6 weeks (41). Despite its promising results, however, the study is subject to several pitfalls, including absence of a placebo control arm, limited sample size, and limited documentation regarding effectiveness of the chosen vitamin D repletion regimen (Table 3), which may affect the generalizability and overall interpretation of the results.
The remaining 3 studies designed to evaluate the effect of vitamin D therapy in viral upper respiratory tract infection (URI) were performed in follow-up to larger trials of vitamin D supplementation for bone loss and fracture prevention in older adults. The study by Avenell et al (43) included a large sample size of 3,444 community-dwelling elderly subjects who were given 800 IU of vitamin D or placebo for longer than 2 years, as part of the Randomised Evaluation of Calcium or Vitamin D (RECORD) trial (49). This study failed to show a significant difference between the vitamin D and placebo groups in either the primary end point of fracture prevention or the secondary end point of self-reported infection rate in the week before assessment (43) (Table 3). The results of the RECORD study, however, are complicated by poor observed compliance with supplements in the study population, with only 54.5% of study subjects remaining compliant with study medication at 24 months of follow-up (43). Another trial, by Aloia and Li-Ng (42), included 208 healthy postmenopausal African American women who were given 800 IU of vitamin D daily or placebo for 2 years, followed by 2,000 IU of vitamin D daily or placebo for 12 months. Although the primary outcome of bone mineral density in the original study (50) demonstrated no significant difference between the 2 groups, a lower rate of self-reported URI or influenza was observed in the intervention arm in comparison with the placebo group, and this effect was further magnified with an increase in the vitamin D dosage from 800 IU daily to 2,000 IU daily (42). Of note, in contrast to the study by Avenell et al (43), which demonstrated relatively meager increases in serum 25-OHD levels of the intervention group after vitamin D therapy (Table 3), the trial by Aloia and Li-Ng (42) reported follow-up mean serum 25-OHD levels commensurate with the current definition of vitamin D sufficiency at levels of 25-OHD ≥32 ng/mL (48). This difference in study design highlights the putative importance of ensuring adequate vitamin D repletion (at least >30 to 32 ng/mL) to maximize its extraskeletal and immunomodulatory effects in future intervention trials.
A recently published dedicated follow-up study by Li-Ng et al (47), however, in which 162 healthy adults were given 2,000 IU of cholecalciferol or placebo daily for 12 weeks during the winter and spring months of 2007, showed no benefit in its 2 primary outcomes—the incidence and the severity of URI symptoms—for the vitamin D group versus the placebo group. This lack of significant difference in outcome was noted despite appropriate increases in serum 25-OHD levels in the intervention group, with a mean level of 25.72 ng/mL at baseline and 35.4 ng/mL at 12 weeks (Table 3). The authors emphasized that although no major benefit of prevention of URI was observed in this study, the statistical trend appeared to favor the vitamin D-receiving group. This finding suggests that a larger sample size and more robust vitamin D repletion, perhaps for a longer period, may be beneficial in the design of future studies.
Two additional studies evaluated the role of vitamin D as adjuvant therapy to boost hepatitis B (40) and influenza vaccine responses (44) as a novel approach to using vitamin D as preventive therapy for viral infection. Moe et al (40) treated 31 hemodialysis patients with the vitamin D analogue paricalcitol for 12 weeks (Table 3) in an effort to improve the blunted immunogenicity profile of hepatitis B vaccine seen in patients with end-stage renal disease and hemodialysis (51). Similarly, Kriesel and Spruance (44) administered single intramuscular doses of 40 IU of vitamin D or saline placebo to attempt to boost immune responses after influenza vaccination in 175 healthy volunteers. Neither study demonstrated a significant increase in hepatitis B or hemagglutination titers in the intervention group in comparison with the placebo group (Table 3). Future studies in the field of vitamin D and vaccine immunology should include a more rigorous focus on clinical and immunologic effectiveness of dose-finding repletion strategies and more detailed documentation of baseline and follow-up vitamin D levels after therapy.
Although a small Norwegian study demonstrated an association between low 1,25-(OH)2D levels and the rate of CD4 count decline and HIV-related mortality (52), few prospectively designed clinical studies have been done to determine any causal relationship among host vitamin D status, immunologic decline, and clinical outcomes in HIV-seropositive patients. Some large studies of multivitamin and micronutrient formulations containing modest doses of vitamin D have demonstrated decreases in morbidity and mortality when given to HIV-positive patients in developing countries, especially those concurrently infected with M tuberculosis (53,54), but it is difficult to extrapolate any vitamin D-specific effects from these data.
Our search criteria identified 1 recent randomized placebo-controlled trial of isolated vitamin D therapy in a pediatric HIV-positive population. Arpadi et al (45) reported administering 100,000 IU of cholecalciferol or placebo bimonthly during a period of 12 months to 56 HIV-positive children and adolescents, with or without antiretroviral therapy, to evaluate the effect of vitamin D treatment on immunologic and clinical outcomes such as weight gain, mean CD4 count, and adequacy of viral load control. Although 44.4% of study subjects in the vitamin D group were documented to have 25-OHD levels of 30 ng/mL or higher at the end of the study follow-up, the study did not demonstrate a statistically significant difference between the 2 groups in gains in CD4 count or improvements in virologic control (45). Because of the potential antagonistic relationship between antiretroviral therapy and vitamin D metabolism, particularly its effect on 1,25-(OH)2D, rather than 25-OHD levels, as suggested by the literature, future trials in this area may benefit from a study design that includes a larger study population, more aggressive vitamin D dosing to achieve levels of 25-OHD considered optimal, and stratification on the basis of the subjects' antiretroviral regimen. These steps may help to delineate nuances of the complex immunologic phenomena associated with this disease process.
In summary, the role of vitamin D status in modulating host immune responses to viral infection, ranging from HIV to the common cold, appears complex, and few controlled clinical intervention studies have been performed to help illustrate the full therapeutic potential of vitamin D as an adjunctive or preventive strategy in these settings. Initial promising results from studies evaluating the prevalence of viral URI and influenza in vitamin D-treated subjects can be informative for future trials in this field. Additional information from both clinical and laboratory-driven studies is clearly needed to help elucidate the complex interplay among vitamin D status, vitamin D metabolism, and HIV infection in the human host.
Intervention trials of vitamin D in other infections, such as diseases caused by fungi, protozoa, or other parasites, are very limited. Our search identified only 1 such trial (Table 4), by Snyman et al (46), in which 59 adolescents received 40 IU of vitamin D or placebo daily for 5 days in a 2-by-2 factorial design with or without antiparasitic therapy for Schistosoma haematobium infection, a common parasitic illness in the developing world. The results of the study by Snyman et al (46) contribute to the limited body of knowledge on this topic by demonstrating some positive effects on levels of activated eosinophils and Schistosoma-specific antibodies in the vitamin D group, although no overt clinical benefit was noted.
Recent studies have described a high prevalence of vitamin D insufficiency and overt vitamin D deficiency in human populations worldwide (48). As our knowledge of the extraskeletal functions of vitamin D continues to grow, the clinical significance of maintaining vitamin D sufficiency becomes more apparent. Several of the studies reviewed in this report build on existing preclinical research in vitamin D immunology, which demonstrates a likely connection among vitamin D repletion, susceptibility to infection, and clinical outcomes in a variety of infectious processes. On the basis of studies reviewed to date, the strongest evidence (in the form of rigorous clinical trials) supports further research into adjunctive vitamin D therapy for tuberculosis, influenza, and viral upper respiratory tract illnesses. Some of the studies we discussed also included nonspecific outcomes, demonstrating that adequate vitamin D status may decrease all-cause infection rates in the populations analyzed (40,41,43). Although these investigations yielded mixed results (40,43), future population-based studies to evaluate broad effects of vitamin D supplementation on infection rates and total mortality may be warranted.
Collectively, the results of the studies discussed in this report highlight the need for more research for further characterization of the complex interplay among vitamin D deficiency, vitamin D repletion, and host response to infectious diseases, as well as for extraction of specific, clinically relevant effects of vitamin D repletion in these settings. As a result of this review, several themes emerge that should be considered in the design of future studies to evaluate the role of vitamin D therapy for infectious diseases. First, the therapeutic potential of vitamin D-based interventions can be assessed only if there is adequate documentation of the effectiveness of the selected repletion regimen in terms of improving the vitamin D status of the host—that is, an increase in serum 25-OHD levels. Therefore, measurement and reporting of prerepletion and postrepletion serum 25-OHD levels must be an essential component of future studies in this field. Second, recent strides toward defining "vitamin D sufficiency" as a serum 25-OHD level >30 to 32 ng/mL (48) create a good target to frame future studies of vitamin D supplementation and to standardize vitamin D repletion protocols. The immunomodulatory and antimicrobial effects of vitamin D, however, may require higher serum 25-OHD levels, thus necessitating more aggressive dosing schemes, as suggested by the results of the TB treatment study conducted by Wejse (35) in Guinea-Bissau and the recent URI study conducted by Li-Ng et al (47). Therefore, dose-ranging studies may be necessary to establish repletion thresholds to guide further studies evaluating the extraskeletal effects of vitamin D. Finally, other limitations similar to those identified in this review, such as limited sample size and poorly defined disease-specific treatment end points, may confound future prospective studies in the field of vitamin D immunology. Rigorous study design will be key in achieving clinical confirmation of hypotheses derived at the bench, in preclinical studies, or in animal models of vitamin D deficiency and will help delineate necessary changes in clinical practice and medical care of patients with vitamin D deficiency.
This work was supported by National Institutes of Health grants T32DK007298 (to A.V.Y.), K24 RR023356 (to T.R.Z.), and K23 AR054334 (to V.T.).
We thank Dr. Roberto Pacifici, principal investigator of National Institutes of Health grant T32DK007298, for his generous support of work related to this publication.
The authors have no conflicts of interest to disclose.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Texas, FPL, GE, Xcel Winners In Latest AWEA Rankings
Wind energy leaders in most categories held onto their #1 positions in the American Wind Energy Association's annual rankings of U.S. wind power leadership (PDF).
The new listings, based on numbers compiled at the end of 2007, closely resemble those from the previous year, with Texas tops among states in both total and new wind power, FPL Energy operating the nation's largest wind farms, GE Energy capturing the largest U.S. market share for wind turbines, and Xcel Energy boasting more wind on its system than any other investor-owned utility.
A broadening of categories this year did reveal some new front-runners, though: Iowa leads the nation in wind generation on a percentage basis, obtaining 5.5 percent of its electricity from the source, while Great River Energy and CPS Energy led the pack among rural electric cooperatives and municipal utilities, respectively. Turbines built by manufacturer Vestas, meanwhile, are the largest installed in the U.S.
With total installed U.S. wind power capacity now over 16,800 MW, or enough to serve the equivalent of 4.5 million average households, wind was the second largest source of new electrical capacity in the nation, behind only natural gas, for the past three years.
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Killzone port heading to PSN on January 24
Sony will release a port of 2004's Killzone for PS2 via PlayStation Network on January 24. The news was confirmed to GameInformer after a listing for the game was found on the ESRB website. Upon release it will run you $9.99. Thanks, Eurogamer.
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If you check out http://www.lacrosse-lounge.com youll notice the subscribe form but its not where i need it i need it aligned to the right in the navigation bar just like how the search bar used to be.
Home Location about us .. .. [sign up for newsletter] [Subscribe]
the above is how it should kind of look . Its been a stuggle to do this ive been at it for hours. Any help is greatly appreciated thank you


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Why one should never trust a spelling checker...
I admit it. I make errors. Public ones. Like writing this:
For those of us who were once English teachers, to funny not to share... Doug
And of course, the misspelling was brought to my attention:
I am a devout reader of your blog (not that I always agree with you), but I felt, as an English teacher, the need to point out the irony of the mistake in your first sentence...
"For those of us who were once English teachers, to funny not to share"
"too funny"
No offense intended!
So, OK. That was embarrassing. I replied:
Here are the possible reasons I made such an error:
- I deliberately left out the second "o" because my computer is running low on them and I need to conserve.
- I've always been confused about to, too, and 2 (as well as tutu – both the costume and the politician).
- This was actually a contest to see who could find the error – AND YOU WON!
- Like the Navajo blanket weavers, I purposely make an error in each thing I write, honoring the notion that only God is perfect.
- I suck at proofing my own writing and need to take the time to do a better job of it.
Anywho, I will leave the error in situ as a lesson in humility. Thanks for the catch.
All the best,
While making such a dumb mistake and being called on it never exactly makes my day, it doesn't really slow me down much either. Nor should concern about your own writing being perfect prior to publication keep you from writing and publishing. Fear of errors keeps too (or to) many people from contributing to the common good.
After writing I don't know how many words in books, articles, columns and this dumb blog, you'd think I would get better at crafting a decent sentence and avoiding typos. But I still can't re-read a single thing I've written without the urge to re-write - even if just a little. And deliberate or not, I bet almost everything I've written still has grammar or spelling errors still in it.
On a completely un-related note, my buddy Ian Jukes is still suffering from a foot infection. In my last email to him, I suggested that he simply lose the foot and attach a wheel or inline skate or even a little skateboard. I listed several advantages:
- easier to make close connections at airports with new speed
- add a few LED lights and do a big "Starlight Express" number as a finale to his keynotes
- big down hills = no need for taxis
- twice the life from one pair of socks
- add a generator to recharge the laptop and cell phone
I am sure there are other benefits as well. But I also realize that he is probably more attached to his foot than I am. This is my Heely-envy coming out. When will they make these things for my size weight person?
Could this be Ian's big finish to his future keynotes?


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Results 271 — 280
MTS Fashion Internship Assistant
Freckled LLC/Morgan Taylor Scrubs — Virtual
January 14 2016
Welcome to Morgan Taylor Scrubs, new scrubs with a twist. Launching Spring 2016, we are excited to bring to you new scrubs with a twist. Morgan Taylor Scrubs is a transformational and stylishly fitted…
Application Deadline: Available Year-round
Fashion Editor interns - NY only
FV MAGAZINE — Virtual
May 08 2016
FV magazine endeavors to showcase the work of some of the world's best artisans and emerging photographers , stylists , writers to create a forum that inspires the passionate, about the beauty of pop …
Application Deadline: Available Year-round
Fashion Jewelry Showroom Intern
Shashi — New York, NY
January 08 2016
Shashi Inc is a costume jewelry brand known for its eclectic, colorful jewelry. We are sold in many boutiques and stores worldwide, including Shopbop, Scoop, and Bloomingdales. Responsibilities includ…
Application Deadline: Available Year-round
Fashion PR Intern
Refine — Washington, DC
January 07 2016
This is a unique opportunity for a bright individual seeking hands-on experience in the fashion retail world and PR.
Application Deadline: Available Year-round
Showroom Internship
Scarlett Showroom — New York, NY
July 11 2016
Scarlett Showroom is looking for a creative and organized individual to intern fall 2016! Scarlett is located in New York City right in the heart of Soho and represents several contemporary designers …
Application Deadline: 8/26/2016
Fashion Public Relations Internship
CARO Marketing — Los Angeles, CA
January 05 2016
We are seeking star interns who are creative, resourceful, self-starters, doers, and problem solvers with an upbeat personality! Must be eager to learn the real behind the scenes work done by the fash…
Application Deadline: Available Year-round
Fashion Showroom Intern
Starworks Group — New York, NY
January 05 2016
SWG is a global brand development agency, specializing in creative strategies that en-gage audiences and catalyze business performance. Our partners are forward-thinking businesses who embrace new and…
Application Deadline: Available Year-round
Fashion Interns Wanted
L.I.A.R. Boutique, LLC — Atlanta, GA
January 04 2016
Life Is A Runway brand is currently seeking fashionable interns! Our brand includes www.liarboutique.com, an online women's fashion website and Life Is A Runway Showroom (@lifeisarunwaysr), a boutique…
Application Deadline: Available Year-round
Soho New York City Fashion Design Internship
Miss Circle LLC — New York, NY
May 06 2016
We are an online fashion boutique that is offering an in-house fashion Production / Design Internship. Location: Soho, New York City Position: Fashion Design Internship Hours/Week: 10-20 hours/week Co…
Application Deadline: Available Year-round
Fashion Blogger/Writer for Option Fashion
Option Fashion — Virtual
March 15 2016
I am the creator of Option Fashion and in need of 3 fashion bloggers to help me with blog posts and social media. PLEASE apply if you meet the requirements and love to write! For people who don't have…
Application Deadline: Available Year-round


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I have a Hammer slider with a metric system installed on the fence. It's actually a much easier way to cut things and even build. Why haven't we simply adopted the metric system in the USA? It would prove much easier to figure fractions for those folks who are fraction challenged.Last Post By: Jim Koepke Today, 12:32 PM
Maybe I got lucky. My flattening of the White stone took about an hour,using a used diamond stone. It was slightly out of flat,and had a fuzzy spot of ceramic that had to go. I have seen pictures of "sawn" looking ceramic stones by Spyderco(my brand),but haven't encountered one personally. I got...Last Post By: Tom M King Today, 3:47 PM
Hello all just want to tell you about a problem I am having with Access Used Lasers. They sold my laser per an agreement we had. Received $6000.00 deposit. After they sold the laser they did not pay me the last $6000.00. Now they are not answering my phone calls. I trusted Robert now it looks like...Last Post By: Nancy Laird Today, 3:30 PM
Hello all, Someone noted that everybody loves a thread on building a bench (just like you can't have too many clamps?). I'm planning to migrate this thread to SMC: http:// forums.finewoodworking.com/fi...and-bench-dead (Remove the space after // when copying into your browser.) I'll...Last Post By: Brian Holcombe Today, 2:58 PM
:D With all of the sharpening threads at current I feel a bit left out, so I thought I'd blog away and post it up. https://brianholcombewoodworker.com/2016/06/26/japanese-natural-stones-a-users-perspective/ Those asking to be pushed over the edge into natural stones territory may find this...Last Post By: Luke Dupont Today, 1:58 PM
http://www.thisoldhouse.com/toh/video/0,,20924478,00.html Tom Silva's using the table saw to freehand cut @ 57 seconds into the video. I'd think this is a good way to be force fed a piece of material - - but - - this is TOH & Tom Silva.....:confused::confused:Last Post By: Jerome Stanek Today, 2:07 PM
Front to Back / Back to Front (Votes: 4)
Side to Side (Votes: 2)
Circular / Figure eight (Votes: 0)
None of the above (please explain) (Votes: 0)
I voted for what I do the majority of the time, which is primarily straight forward, and backward with the emphasis on forward. I depend on what it feelsTom M King Today, 3:57 PM
I recognize some folks don't like to be put in a box or labeled "so and so", but for the greater good, please select your favorite method.Pat Barry Today, 3:50 PM
That picture really shows the figure and grain of the wood, really spectacular piece Doug, well doneLeo Van Der Loo Today, 3:49 PM
I had missed this thread, or at least don't remember posting in it. I don't use ceramic stones because I don't like the lack of feel. My sharpeningTom M King Today, 3:47 PM
Took a day off vacation time to give myself an extra day to get my bunk bed project over the hump of indecision I've been stuck in lately. Found the rightMike Ontko Today, 3:47 PM


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SAN DIEGO (AP) - A San Diego police officer who shot and killed a transient within seconds of exiting his car initially told investigators that he didn't see a weapon but said days later that he recalled thinking the man might be carrying a knife, according to a report released Wednesday.
CLAREMONT . (AP) - For the last eight years, a Southern California church has hosted an artist's socially provocative Nativity scenes addressing issues such as homelessness and immigration.
LOS ANGELES (AP) - It's not just a junkyard - or even a really big junkyard - but a living, breathing monument to Los Angeles pop culture. And now it's headed for the dustbin of history itself.
SAN FRANCISCO (AP) - The University of California has decided to unload at least $25 million worth of stock in three private prison companies following a campaign by black student activists from the system's 10 campuses, a spokeswoman confirmed Tuesday.
SAN DIEGO (AP) - The San Diego County district attorney released a video Tuesday that shows a police officer fatally shooting a transient seconds after the officer left his patrol car as the man walked toward him.
SAN JOSE (AP) - Security researcher Brian Wallace was on the trail of hackers who had snatched a California university's housing files when he stumbled into a larger nightmare: Cyberattackers had opened a pathway into the networks running the United States' power grid.
FRESNO - California regulators on Monday proposed relaxing water conservation targets that have required communities statewide to cut use by 25 percent during historic drought.
SAN DIEGO (AP) - The owners of a janitorial company serving luxury hotels in Southern California and Nevada are charged with running a $7 million workers' compensation insurance and tax evasion scam, prosecutors announced Monday.
LOS ANGELES (AP) - To say that the force is strong with this one is an understatement.
BAKERSFIELD (AP) - Rescuers pulled five bodies from the wreckage of a small plane that crashed into an orchard in central California after vanishing from radar, local and federal authorities said Sunday.
SAN FRANCISCO (AP) - One of the nation's most prominent medical centers has voluntarily suspended its living donor program for kidney transplants after a living donor died last month.
TORRANCE (AP) - A man brought to a hospital after attacking police was shot to death by a Los Angeles officer in the emergency room after he swung a metal stool and grabbed for an officer's gun, authorities said.
LOS ANGELES (AP) - The San Bernardino attack that left 14 people dead represented a type of extremist plot law enforcement authorities consider exceedingly difficult to detect: a conspiracy between close family members.
Manteca Fire Department Debbie Williams administrative assistant Debbie Williams is retiring.
A special Christmas program is planned for this Sunday, Dec. 20, at 11 a.m. at The Church of Jesus Christ of Latter Day Saints, 6060 Northland Road in Manteca.
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COALINGA (AP) - An animal welfare organization says the state's last known gas chamber used to euthanize cats and dogs has been dismantled.
SAN FRANCISCO (AP) - The body of a girl found last month inside a small metal casket still holding a rose was laid to rest 145 ...
LOS ANGELES (AP) - Nearing the end of the primary season, a defiant Bernie Sanders predicted Saturday that the Democratic presidential process would lead to a ...
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1) Former Atlantan Josh Kilmer-Purcell reads and discusses his book, Candy Everybody Wants, at Outwrite Bookstore & Coffeehouse.
2) R&B songstress Alicia Keys performs at Philips Arena.
3) Jordan Eagle uses his own blood in New Blood, his exhibit opening at Krause Gallery.
4) Augustana performs at Variety Playhouse.
5) Author James Rollins discusses his book, Indiana Jones and the Kingdom of the Crystal Skull, at Wordsmiths Books.
(Image courtesy Amazon.com)


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I'm sure you have strong thoughts and powerful feelings about the current events in the world right now. I do. I have the thoughts, the feelings, but the words to express them, those I've been struggling with. I'm grateful for those who have managed to sort out their own house enough to help me work on mine: how is this world is so ... [Continue Reading]
Authenticity. Really, Why Does It Matter? Why Now?
You can't buy authenticity. You don't learn it from a book. You don't pick it up at a workshop. Billions are spent every year on products, courses, consultants, training, coaching, facilitation on big questions such as who am I/we, what do I/we stand for, how can I/we show up as the most genuine, real, congruent, honest version of ... [Continue Reading]
You Aren't Hiking Up the 'Be True to Yourself' Path Alone. Really.
The path to remaining true to yourself is like a life-long trek up the side of a treacherous mountain. If the exposure doesn't get to you first there are always the tough scrambles, steep ledges, crumbling rocks, plenty of opportunities to get sidetracked and lost, wrong signposts, misinformation, and almost certainly no shortcuts or hacks. Once ... [Continue Reading]
So Fear, What Outfit Are You Wearing Today?
Fear stops us. It's the only thing that holds us back. I'm sure, like me, you've felt fear in its physical form: anxiety, stress, sweat palms, dry mouth, butterflies in your stomach, heart pounding, anger. That fear is obvious in it's sensational attire. But it has other costumes. It owns a wardrobe of many outfits. The physical response to ... [Continue Reading]
The Diet of It's Not Quite Right (Or Stop Stalling)
Imagine for a moment you're a Neurosurgeon. You're scrubbed up and ready to perform an emergency life-saving operation. Everything is in place. In the theatre with you are a second surgeon, your surgical assistant, a couple of technicians, the Anesthesiologist, and their nursing assistant, the scrub nurse, and the Circulating nurse, the Holding ... [Continue Reading]
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